ORF_ID e_value Gene_name EC_number CAZy COGs Description
FHHGHNIK_00001 2.5e-91 clcA P chloride
FHHGHNIK_00002 3e-60 GM NmrA-like family
FHHGHNIK_00003 1.6e-31 S RelB antitoxin
FHHGHNIK_00004 2.8e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FHHGHNIK_00005 4.4e-121 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
FHHGHNIK_00006 4.2e-164 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
FHHGHNIK_00007 4.6e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FHHGHNIK_00008 2.6e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
FHHGHNIK_00009 8.9e-237 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
FHHGHNIK_00010 1.6e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FHHGHNIK_00011 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
FHHGHNIK_00016 6.9e-39
FHHGHNIK_00017 2.7e-34 glcU U sugar transport
FHHGHNIK_00018 2.8e-27 glcU U sugar transport
FHHGHNIK_00019 1.5e-47 glcU U sugar transport
FHHGHNIK_00020 1.1e-46
FHHGHNIK_00021 6.4e-75 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
FHHGHNIK_00022 1.9e-147 2.7.1.89 M Phosphotransferase enzyme family
FHHGHNIK_00023 1.8e-144 2.4.2.3 F Phosphorylase superfamily
FHHGHNIK_00024 6e-140 2.4.2.3 F Phosphorylase superfamily
FHHGHNIK_00025 8.1e-119 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
FHHGHNIK_00026 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
FHHGHNIK_00027 4.7e-11 S Bacterial PH domain
FHHGHNIK_00028 5.7e-18 S Bacterial PH domain
FHHGHNIK_00029 4e-27
FHHGHNIK_00030 1.1e-64 arsC 1.20.4.1 P Belongs to the ArsC family
FHHGHNIK_00031 2.3e-175 I Carboxylesterase family
FHHGHNIK_00033 1.6e-174 M Glycosyl hydrolases family 25
FHHGHNIK_00034 0.0 S Predicted membrane protein (DUF2207)
FHHGHNIK_00035 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
FHHGHNIK_00036 6.1e-128 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
FHHGHNIK_00037 5.3e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
FHHGHNIK_00038 7.2e-253 S Uncharacterized protein conserved in bacteria (DUF2325)
FHHGHNIK_00039 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
FHHGHNIK_00040 1e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
FHHGHNIK_00041 1.7e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
FHHGHNIK_00042 1.2e-100 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FHHGHNIK_00043 3.1e-69 yqhY S Asp23 family, cell envelope-related function
FHHGHNIK_00044 4e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FHHGHNIK_00045 1.3e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FHHGHNIK_00046 1.5e-194 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FHHGHNIK_00047 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FHHGHNIK_00048 1.2e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
FHHGHNIK_00049 5.8e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
FHHGHNIK_00050 1.8e-306 recN L May be involved in recombinational repair of damaged DNA
FHHGHNIK_00051 3.8e-78 6.3.3.2 S ASCH
FHHGHNIK_00052 8.9e-110 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
FHHGHNIK_00053 9.4e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
FHHGHNIK_00054 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FHHGHNIK_00055 2.8e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FHHGHNIK_00056 2.3e-243 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FHHGHNIK_00057 8.6e-145 stp 3.1.3.16 T phosphatase
FHHGHNIK_00058 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
FHHGHNIK_00059 1.8e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
FHHGHNIK_00060 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
FHHGHNIK_00061 5.3e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
FHHGHNIK_00062 8.8e-50
FHHGHNIK_00063 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
FHHGHNIK_00064 6.8e-57 asp S Asp23 family, cell envelope-related function
FHHGHNIK_00065 1.4e-303 yloV S DAK2 domain fusion protein YloV
FHHGHNIK_00066 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FHHGHNIK_00067 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
FHHGHNIK_00068 4.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
FHHGHNIK_00069 6.8e-195 oppD P Belongs to the ABC transporter superfamily
FHHGHNIK_00070 3.5e-180 oppF P Belongs to the ABC transporter superfamily
FHHGHNIK_00071 5.2e-173 oppB P ABC transporter permease
FHHGHNIK_00072 4.4e-145 oppC P Binding-protein-dependent transport system inner membrane component
FHHGHNIK_00073 0.0 oppA E ABC transporter substrate-binding protein
FHHGHNIK_00074 0.0 oppA E ABC transporter substrate-binding protein
FHHGHNIK_00075 3.2e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
FHHGHNIK_00076 0.0 smc D Required for chromosome condensation and partitioning
FHHGHNIK_00077 2.4e-165 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FHHGHNIK_00078 4.7e-287 pipD E Dipeptidase
FHHGHNIK_00079 1.2e-18
FHHGHNIK_00080 1.2e-255 yfnA E amino acid
FHHGHNIK_00081 3.2e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FHHGHNIK_00082 1.4e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FHHGHNIK_00083 4.5e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
FHHGHNIK_00084 4.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FHHGHNIK_00085 8.5e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
FHHGHNIK_00086 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
FHHGHNIK_00087 2.8e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
FHHGHNIK_00088 1.3e-145 E GDSL-like Lipase/Acylhydrolase family
FHHGHNIK_00089 9.7e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FHHGHNIK_00090 2.5e-37 ynzC S UPF0291 protein
FHHGHNIK_00091 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
FHHGHNIK_00092 7e-293 mdlA V ABC transporter
FHHGHNIK_00093 1.2e-295 mdlB V ABC transporter
FHHGHNIK_00094 0.0 pepO 3.4.24.71 O Peptidase family M13
FHHGHNIK_00095 3.8e-226 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
FHHGHNIK_00096 1.9e-112 plsC 2.3.1.51 I Acyltransferase
FHHGHNIK_00097 2.9e-198 yabB 2.1.1.223 L Methyltransferase small domain
FHHGHNIK_00098 8.8e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
FHHGHNIK_00099 2.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FHHGHNIK_00100 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
FHHGHNIK_00101 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
FHHGHNIK_00102 1e-136 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FHHGHNIK_00103 1.6e-146 cdsA 2.7.7.41 I Belongs to the CDS family
FHHGHNIK_00104 8.8e-197 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
FHHGHNIK_00105 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
FHHGHNIK_00106 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FHHGHNIK_00107 3.2e-83 rimP J Required for maturation of 30S ribosomal subunits
FHHGHNIK_00108 1.5e-193 nusA K Participates in both transcription termination and antitermination
FHHGHNIK_00109 3.8e-44 ylxR K Protein of unknown function (DUF448)
FHHGHNIK_00110 1.2e-46 rplGA J ribosomal protein
FHHGHNIK_00111 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FHHGHNIK_00112 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FHHGHNIK_00113 3.7e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FHHGHNIK_00114 1e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
FHHGHNIK_00115 1.4e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
FHHGHNIK_00116 6.7e-83 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FHHGHNIK_00117 0.0 dnaK O Heat shock 70 kDa protein
FHHGHNIK_00118 3.9e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
FHHGHNIK_00119 1e-31 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
FHHGHNIK_00120 1.1e-192 pbpX1 V Beta-lactamase
FHHGHNIK_00121 0.0 L Helicase C-terminal domain protein
FHHGHNIK_00122 3.4e-121 E amino acid
FHHGHNIK_00123 6.7e-119 E amino acid
FHHGHNIK_00124 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
FHHGHNIK_00125 2e-168 yniA G Phosphotransferase enzyme family
FHHGHNIK_00126 3.4e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHHGHNIK_00127 8.6e-133 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
FHHGHNIK_00128 9.5e-178 ABC-SBP S ABC transporter
FHHGHNIK_00129 1.1e-124 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
FHHGHNIK_00130 1.1e-136 XK27_08845 S ABC transporter, ATP-binding protein
FHHGHNIK_00131 1.6e-50
FHHGHNIK_00132 1.3e-11
FHHGHNIK_00133 3.4e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
FHHGHNIK_00134 2.4e-168 K AI-2E family transporter
FHHGHNIK_00135 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
FHHGHNIK_00136 2.5e-84 S ECF transporter, substrate-specific component
FHHGHNIK_00137 6e-97 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
FHHGHNIK_00138 3.6e-148 S Putative ABC-transporter type IV
FHHGHNIK_00139 1.1e-229 S LPXTG cell wall anchor motif
FHHGHNIK_00140 4.1e-251 pipD E Dipeptidase
FHHGHNIK_00141 1.7e-176 V Restriction endonuclease
FHHGHNIK_00142 5.3e-18 V Restriction endonuclease
FHHGHNIK_00143 3.2e-89 K Bacterial regulatory proteins, tetR family
FHHGHNIK_00144 1.7e-57 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FHHGHNIK_00145 4.3e-130 ybbM S Uncharacterised protein family (UPF0014)
FHHGHNIK_00146 2.9e-111 ybbL S ABC transporter, ATP-binding protein
FHHGHNIK_00147 1.3e-27 WQ51_00220 K Helix-turn-helix XRE-family like proteins
FHHGHNIK_00149 7.5e-244 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FHHGHNIK_00151 1.7e-120 yhiD S MgtC family
FHHGHNIK_00152 8.2e-240 I Protein of unknown function (DUF2974)
FHHGHNIK_00153 2.3e-35
FHHGHNIK_00155 1.1e-126 pgm3 G Phosphoglycerate mutase family
FHHGHNIK_00156 1.7e-125 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
FHHGHNIK_00157 0.0 helD 3.6.4.12 L DNA helicase
FHHGHNIK_00158 1.2e-78
FHHGHNIK_00161 0.0 pepO 3.4.24.71 O Peptidase family M13
FHHGHNIK_00162 4.8e-55 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FHHGHNIK_00163 5.5e-113 XK27_11280 S Psort location CytoplasmicMembrane, score
FHHGHNIK_00165 2.1e-09
FHHGHNIK_00166 1.3e-32
FHHGHNIK_00167 4e-14
FHHGHNIK_00168 1.5e-26
FHHGHNIK_00169 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
FHHGHNIK_00170 1.2e-38 K LysR substrate binding domain
FHHGHNIK_00171 5.6e-50 K LysR substrate binding domain
FHHGHNIK_00172 1.2e-106 K Transcriptional regulator, LysR family
FHHGHNIK_00173 4.7e-165 arbZ I Phosphate acyltransferases
FHHGHNIK_00174 1.3e-81 arbY M Glycosyl transferase family 8
FHHGHNIK_00175 1.5e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
FHHGHNIK_00176 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
FHHGHNIK_00177 2.3e-29 secG U Preprotein translocase
FHHGHNIK_00178 1.8e-54 3.1.21.3 V Type I restriction modification DNA specificity domain
FHHGHNIK_00179 5.1e-63 S GIY-YIG catalytic domain
FHHGHNIK_00180 6.3e-45 S Domain of unknown function (DUF4298)
FHHGHNIK_00183 6.1e-71 yeaL S Protein of unknown function (DUF441)
FHHGHNIK_00184 1.3e-09
FHHGHNIK_00185 4e-145 cbiQ P cobalt transport
FHHGHNIK_00186 4e-270 ykoD P ABC transporter, ATP-binding protein
FHHGHNIK_00187 1.1e-120
FHHGHNIK_00188 2.4e-142 K Helix-turn-helix XRE-family like proteins
FHHGHNIK_00189 1.5e-26 KLT serine threonine protein kinase
FHHGHNIK_00190 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FHHGHNIK_00191 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FHHGHNIK_00192 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
FHHGHNIK_00193 2.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
FHHGHNIK_00195 1.6e-08
FHHGHNIK_00196 6.6e-26
FHHGHNIK_00197 1.7e-27
FHHGHNIK_00199 3.5e-296 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
FHHGHNIK_00200 8e-196 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FHHGHNIK_00201 5.5e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FHHGHNIK_00202 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FHHGHNIK_00203 3.8e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
FHHGHNIK_00204 2.9e-60 yabR J S1 RNA binding domain
FHHGHNIK_00205 2.6e-59 divIC D Septum formation initiator
FHHGHNIK_00206 1.8e-34 yabO J S4 domain protein
FHHGHNIK_00207 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FHHGHNIK_00208 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
FHHGHNIK_00209 2.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
FHHGHNIK_00210 7.1e-127 S (CBS) domain
FHHGHNIK_00211 3.6e-89 K transcriptional regulator
FHHGHNIK_00212 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FHHGHNIK_00213 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
FHHGHNIK_00214 9.4e-246 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
FHHGHNIK_00215 5.3e-264 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
FHHGHNIK_00216 1.9e-39 rpmE2 J Ribosomal protein L31
FHHGHNIK_00217 1.9e-27 sagB C Nitroreductase family
FHHGHNIK_00219 2.8e-171 yfdH GT2 M Glycosyltransferase like family 2
FHHGHNIK_00220 1.6e-65 2.4.1.83 GT2 S GtrA-like protein
FHHGHNIK_00221 4.2e-89 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
FHHGHNIK_00222 1.5e-55 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
FHHGHNIK_00223 7.4e-22
FHHGHNIK_00224 3.7e-88
FHHGHNIK_00225 1.1e-95
FHHGHNIK_00226 8.8e-09 S ACT domain
FHHGHNIK_00227 6.1e-182 S Domain of unknown function (DUF389)
FHHGHNIK_00228 3.9e-14 S CRISPR-associated protein (Cas_Csn2)
FHHGHNIK_00229 9.3e-89 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FHHGHNIK_00230 5.2e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
FHHGHNIK_00231 2.8e-216 yceI EGP Major facilitator Superfamily
FHHGHNIK_00232 4.2e-275 E Amino acid permease
FHHGHNIK_00234 1.9e-175 V ABC transporter transmembrane region
FHHGHNIK_00235 1.7e-42 KLT serine threonine protein kinase
FHHGHNIK_00236 9.4e-161 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FHHGHNIK_00237 6.1e-152 glcU U sugar transport
FHHGHNIK_00238 4.9e-95 pbpX2 V Beta-lactamase
FHHGHNIK_00239 4.2e-42 pbpX2 V Beta-lactamase
FHHGHNIK_00240 2.5e-39 3.2.2.20 K acetyltransferase
FHHGHNIK_00241 2.2e-96
FHHGHNIK_00242 2.9e-37
FHHGHNIK_00243 3.3e-16
FHHGHNIK_00244 7.1e-99 soj D CobQ CobB MinD ParA nucleotide binding domain protein
FHHGHNIK_00245 7.2e-176 S SLAP domain
FHHGHNIK_00246 1.9e-138 S Bacteriocin helveticin-J
FHHGHNIK_00248 1.2e-52 3.6.4.12 S PD-(D/E)XK nuclease family transposase
FHHGHNIK_00249 1.5e-138 S Uncharacterized protein conserved in bacteria (DUF2263)
FHHGHNIK_00250 1.5e-59
FHHGHNIK_00251 0.0 lhr L DEAD DEAH box helicase
FHHGHNIK_00252 6.1e-249 P P-loop Domain of unknown function (DUF2791)
FHHGHNIK_00253 3.2e-256 S TerB-C domain
FHHGHNIK_00254 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
FHHGHNIK_00256 6.4e-37
FHHGHNIK_00257 3.8e-34 4.1.1.44 S Carboxymuconolactone decarboxylase family
FHHGHNIK_00258 1.2e-52 4.1.1.44 S Carboxymuconolactone decarboxylase family
FHHGHNIK_00259 4.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FHHGHNIK_00260 3.7e-92 S LPXTG cell wall anchor motif
FHHGHNIK_00261 3e-26
FHHGHNIK_00262 1.4e-91 yagE E amino acid
FHHGHNIK_00263 8.8e-47
FHHGHNIK_00264 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
FHHGHNIK_00265 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
FHHGHNIK_00266 3.7e-233 cycA E Amino acid permease
FHHGHNIK_00267 2.3e-69 maa S transferase hexapeptide repeat
FHHGHNIK_00268 1.2e-79 K Transcriptional regulator
FHHGHNIK_00269 7.6e-64 manO S Domain of unknown function (DUF956)
FHHGHNIK_00270 1.2e-171 manN G system, mannose fructose sorbose family IID component
FHHGHNIK_00271 6.9e-134 manY G PTS system
FHHGHNIK_00272 1.8e-187 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
FHHGHNIK_00273 3.1e-47 rafA 3.2.1.22 G alpha-galactosidase
FHHGHNIK_00274 1.5e-170 rafA 3.2.1.22 G alpha-galactosidase
FHHGHNIK_00275 1.4e-33 rafA 3.2.1.22 G alpha-galactosidase
FHHGHNIK_00276 1.5e-90 scrA 2.7.1.208, 2.7.1.211 G phosphotransferase system
FHHGHNIK_00277 1e-45 scrA 2.7.1.208, 2.7.1.211 G phosphotransferase system
FHHGHNIK_00278 1e-146 scrA 2.7.1.208, 2.7.1.211 G phosphotransferase system
FHHGHNIK_00279 3.2e-130 scrB 3.2.1.26 GH32 G invertase
FHHGHNIK_00280 9.7e-155 msmR7 K helix_turn_helix, arabinose operon control protein
FHHGHNIK_00281 2.5e-118 guaB2 L Resolvase, N terminal domain
FHHGHNIK_00282 5.6e-192 L Putative transposase DNA-binding domain
FHHGHNIK_00283 2.1e-93 L Putative transposase DNA-binding domain
FHHGHNIK_00284 8.6e-143 cylB V ABC-2 type transporter
FHHGHNIK_00285 1.3e-151 cylA V ATPases associated with a variety of cellular activities
FHHGHNIK_00286 9.7e-49 tnpR L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
FHHGHNIK_00287 9e-58 psiE S Phosphate-starvation-inducible E
FHHGHNIK_00288 2e-214 Q Imidazolonepropionase and related amidohydrolases
FHHGHNIK_00289 1.1e-43 oppA E ABC transporter
FHHGHNIK_00291 1.6e-163 S SLAP domain
FHHGHNIK_00292 0.0 uvrA2 L ABC transporter
FHHGHNIK_00295 7.7e-25 E Preprotein translocase subunit SecB
FHHGHNIK_00296 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
FHHGHNIK_00297 4e-161 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
FHHGHNIK_00298 5e-15 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
FHHGHNIK_00299 2.4e-70 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
FHHGHNIK_00300 7.2e-189 lysC 2.7.2.4 E Belongs to the aspartokinase family
FHHGHNIK_00301 2.3e-221 oxlT P Major Facilitator Superfamily
FHHGHNIK_00302 2.6e-52 L Helix-turn-helix domain
FHHGHNIK_00303 2.3e-14 M Lysin motif
FHHGHNIK_00304 3.6e-68 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
FHHGHNIK_00305 3.6e-178 tcsA S ABC transporter substrate-binding protein PnrA-like
FHHGHNIK_00306 3e-247 xylG 3.6.3.17 S ABC transporter
FHHGHNIK_00307 1.5e-166 yufP S Belongs to the binding-protein-dependent transport system permease family
FHHGHNIK_00308 1.6e-158 yufQ S Belongs to the binding-protein-dependent transport system permease family
FHHGHNIK_00309 0.0 3.6.3.8 P P-type ATPase
FHHGHNIK_00310 7.8e-206 G Major Facilitator Superfamily
FHHGHNIK_00311 3.2e-21
FHHGHNIK_00312 5.1e-47
FHHGHNIK_00313 4.2e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
FHHGHNIK_00314 6.3e-141 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
FHHGHNIK_00315 1.3e-51 S Iron-sulfur cluster assembly protein
FHHGHNIK_00317 4.5e-39
FHHGHNIK_00319 2.8e-28 M NlpC/P60 family
FHHGHNIK_00320 2.8e-23 M NlpC/P60 family
FHHGHNIK_00321 2.1e-29 M NlpC/P60 family
FHHGHNIK_00322 1.3e-66 M NlpC/P60 family
FHHGHNIK_00324 4e-116 G Peptidase_C39 like family
FHHGHNIK_00325 4e-26
FHHGHNIK_00327 2e-29
FHHGHNIK_00328 2.8e-09 S Oxidoreductase family, NAD-binding Rossmann fold
FHHGHNIK_00329 1.5e-33 S Oxidoreductase family, NAD-binding Rossmann fold
FHHGHNIK_00331 6.1e-61 oppA E ABC transporter substrate-binding protein
FHHGHNIK_00332 1.2e-147 cjaA ET ABC transporter substrate-binding protein
FHHGHNIK_00333 6.3e-118 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FHHGHNIK_00334 2.6e-86 P ABC transporter permease
FHHGHNIK_00335 3.2e-105 papP P ABC transporter, permease protein
FHHGHNIK_00336 1.2e-96 S PFAM Archaeal ATPase
FHHGHNIK_00337 4.2e-217 S SLAP domain
FHHGHNIK_00339 1.3e-142 mrr L restriction endonuclease
FHHGHNIK_00340 1.2e-10
FHHGHNIK_00341 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
FHHGHNIK_00342 6.8e-225 S response to antibiotic
FHHGHNIK_00343 6.4e-129
FHHGHNIK_00344 1.3e-12 S SLAP domain
FHHGHNIK_00345 1.2e-63 S SLAP domain
FHHGHNIK_00346 8.5e-21 S Plasmid replication protein
FHHGHNIK_00347 2.4e-65 L Phage integrase family
FHHGHNIK_00349 1.2e-249 L TIGRFAM transposase, IS605 OrfB family
FHHGHNIK_00350 8.3e-79 L Resolvase, N terminal domain
FHHGHNIK_00351 1.4e-83 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
FHHGHNIK_00352 1.4e-79 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
FHHGHNIK_00354 2.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FHHGHNIK_00355 7.2e-242 amtB P ammonium transporter
FHHGHNIK_00356 6e-20
FHHGHNIK_00358 2e-26
FHHGHNIK_00359 1.1e-20
FHHGHNIK_00360 8.7e-16
FHHGHNIK_00361 2.6e-209 V ABC transporter transmembrane region
FHHGHNIK_00362 3.8e-08 L Initiator Replication protein
FHHGHNIK_00363 1.3e-52
FHHGHNIK_00364 6.6e-131
FHHGHNIK_00365 1.9e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FHHGHNIK_00366 2.2e-108 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FHHGHNIK_00367 5.3e-101 G Aldose 1-epimerase
FHHGHNIK_00368 3.9e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
FHHGHNIK_00369 2.1e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
FHHGHNIK_00370 0.0 XK27_08315 M Sulfatase
FHHGHNIK_00371 3e-262 S Fibronectin type III domain
FHHGHNIK_00372 2.8e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FHHGHNIK_00373 4.9e-52
FHHGHNIK_00375 3.9e-256 pepC 3.4.22.40 E aminopeptidase
FHHGHNIK_00376 2.3e-111 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
FHHGHNIK_00377 1e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
FHHGHNIK_00378 4.1e-253 pepC 3.4.22.40 E aminopeptidase
FHHGHNIK_00379 5.1e-64 hsp O Belongs to the small heat shock protein (HSP20) family
FHHGHNIK_00380 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FHHGHNIK_00381 4.9e-114
FHHGHNIK_00383 3.4e-114 E Belongs to the SOS response-associated peptidase family
FHHGHNIK_00384 1.2e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
FHHGHNIK_00385 4.7e-90 comEB 3.5.4.12 F MafB19-like deaminase
FHHGHNIK_00386 1e-108 S TPM domain
FHHGHNIK_00387 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
FHHGHNIK_00388 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHHGHNIK_00389 5.1e-147 tatD L hydrolase, TatD family
FHHGHNIK_00390 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FHHGHNIK_00391 7.9e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
FHHGHNIK_00392 2.9e-38 veg S Biofilm formation stimulator VEG
FHHGHNIK_00393 2.2e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
FHHGHNIK_00394 1.5e-202 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FHHGHNIK_00395 1.2e-30 S SLAP domain
FHHGHNIK_00397 3e-153 S Sucrose-6F-phosphate phosphohydrolase
FHHGHNIK_00398 1.5e-32 S Domain of unknown function (DUF4393)
FHHGHNIK_00399 1.5e-52 L An automated process has identified a potential problem with this gene model
FHHGHNIK_00400 3.5e-99 S SLAP domain
FHHGHNIK_00402 6.1e-150 M Glycosyl hydrolases family 25
FHHGHNIK_00403 3e-114 S Membrane protein involved in the export of O-antigen and teichoic acid
FHHGHNIK_00404 6.3e-85 XK27_08435 K UTRA
FHHGHNIK_00406 3e-20
FHHGHNIK_00407 1.6e-85 C nitroreductase
FHHGHNIK_00408 9.4e-58 S Domain of unknown function (DUF4767)
FHHGHNIK_00409 7.9e-60
FHHGHNIK_00410 1.6e-46 K Helix-turn-helix XRE-family like proteins
FHHGHNIK_00411 1.6e-42 K Helix-turn-helix XRE-family like proteins
FHHGHNIK_00412 1e-131
FHHGHNIK_00413 1.2e-64
FHHGHNIK_00414 2e-14 K Helix-turn-helix XRE-family like proteins
FHHGHNIK_00415 1.6e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FHHGHNIK_00416 7.4e-142 K Helix-turn-helix domain
FHHGHNIK_00417 3.8e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FHHGHNIK_00418 4.6e-216 iscS2 2.8.1.7 E Aminotransferase class V
FHHGHNIK_00419 3.9e-280 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FHHGHNIK_00420 8.9e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FHHGHNIK_00421 6.6e-81 yueI S Protein of unknown function (DUF1694)
FHHGHNIK_00422 1.4e-240 rarA L recombination factor protein RarA
FHHGHNIK_00423 2.5e-35
FHHGHNIK_00424 3.1e-78 usp6 T universal stress protein
FHHGHNIK_00425 1.9e-217 rodA D Belongs to the SEDS family
FHHGHNIK_00426 7.3e-33 S Protein of unknown function (DUF2969)
FHHGHNIK_00427 3.8e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
FHHGHNIK_00428 1.9e-178 mbl D Cell shape determining protein MreB Mrl
FHHGHNIK_00429 5.8e-30 ywzB S Protein of unknown function (DUF1146)
FHHGHNIK_00430 7.7e-55 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
FHHGHNIK_00431 7.6e-237 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FHHGHNIK_00432 7e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FHHGHNIK_00433 4.8e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FHHGHNIK_00434 2.2e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHHGHNIK_00435 3.2e-44 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FHHGHNIK_00436 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHHGHNIK_00437 2.1e-126 atpB C it plays a direct role in the translocation of protons across the membrane
FHHGHNIK_00438 8.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FHHGHNIK_00439 1.9e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
FHHGHNIK_00440 1.9e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
FHHGHNIK_00441 6.9e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FHHGHNIK_00442 2.2e-113 tdk 2.7.1.21 F thymidine kinase
FHHGHNIK_00443 3.8e-246 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
FHHGHNIK_00444 3.8e-54
FHHGHNIK_00445 1.5e-200 V ABC transporter transmembrane region
FHHGHNIK_00446 5.6e-115
FHHGHNIK_00448 2.7e-87 S ABC-2 family transporter protein
FHHGHNIK_00454 8.7e-44 relB L Addiction module antitoxin, RelB DinJ family
FHHGHNIK_00455 1.2e-83
FHHGHNIK_00456 4.6e-76 2.3.1.128 K Acetyltransferase (GNAT) domain
FHHGHNIK_00457 3.5e-97 4.2.1.53 S Myosin-crossreactive antigen
FHHGHNIK_00458 9e-104 4.2.1.53 S Myosin-crossreactive antigen
FHHGHNIK_00459 3.6e-41 4.2.1.53 S Myosin-crossreactive antigen
FHHGHNIK_00460 2e-91 yxdD K Bacterial regulatory proteins, tetR family
FHHGHNIK_00461 8.3e-239 emrY EGP Major facilitator Superfamily
FHHGHNIK_00466 2.1e-96 MA20_25245 K Acetyltransferase (GNAT) domain
FHHGHNIK_00467 9.6e-29 cspA K Cold shock protein
FHHGHNIK_00468 6.5e-142 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
FHHGHNIK_00470 8.4e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FHHGHNIK_00471 7.3e-245 nhaC C Na H antiporter NhaC
FHHGHNIK_00472 1.2e-52
FHHGHNIK_00473 7.1e-119 ybhL S Belongs to the BI1 family
FHHGHNIK_00474 3e-114 S Protein of unknown function (DUF1211)
FHHGHNIK_00475 6.7e-170 yegS 2.7.1.107 G Lipid kinase
FHHGHNIK_00476 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FHHGHNIK_00477 4.2e-259 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
FHHGHNIK_00478 5.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FHHGHNIK_00479 1.5e-206 camS S sex pheromone
FHHGHNIK_00480 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FHHGHNIK_00481 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
FHHGHNIK_00482 7.6e-104 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
FHHGHNIK_00484 3.1e-86 ydcK S Belongs to the SprT family
FHHGHNIK_00485 1.7e-136 M Glycosyltransferase sugar-binding region containing DXD motif
FHHGHNIK_00486 7.8e-258 epsU S Polysaccharide biosynthesis protein
FHHGHNIK_00487 5.6e-222 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
FHHGHNIK_00488 0.0 pacL 3.6.3.8 P P-type ATPase
FHHGHNIK_00489 1.7e-60 pacL 3.6.3.8 P P-type ATPase
FHHGHNIK_00490 3.5e-50 L PFAM transposase, IS4 family protein
FHHGHNIK_00491 5.8e-50 L PFAM transposase, IS4 family protein
FHHGHNIK_00492 1.6e-78 V ABC transporter transmembrane region
FHHGHNIK_00493 4.3e-60 L Transposase
FHHGHNIK_00494 1.7e-156 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
FHHGHNIK_00505 1.8e-63 KLT serine threonine protein kinase
FHHGHNIK_00506 1.1e-76 arbY M Glycosyl transferase family 8
FHHGHNIK_00507 1.2e-15 S SLAP domain
FHHGHNIK_00508 1.2e-16
FHHGHNIK_00509 1.3e-143 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FHHGHNIK_00510 2.5e-98 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FHHGHNIK_00511 5.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
FHHGHNIK_00513 1.9e-132 cobQ S glutamine amidotransferase
FHHGHNIK_00514 9.5e-83 M NlpC/P60 family
FHHGHNIK_00515 5.3e-165 EG EamA-like transporter family
FHHGHNIK_00516 1.1e-107
FHHGHNIK_00517 2.2e-76
FHHGHNIK_00518 7e-31 XK27_05540 S DUF218 domain
FHHGHNIK_00519 9.5e-94 XK27_05540 S DUF218 domain
FHHGHNIK_00520 1.2e-57 yheS_2 S ATPases associated with a variety of cellular activities
FHHGHNIK_00521 1.7e-31 yheS_2 S ATPases associated with a variety of cellular activities
FHHGHNIK_00522 6.6e-84
FHHGHNIK_00523 2e-56
FHHGHNIK_00524 1.7e-243 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FHHGHNIK_00525 5.2e-245 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FHHGHNIK_00526 2.8e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
FHHGHNIK_00529 1e-201 4.2.1.126 S Bacterial protein of unknown function (DUF871)
FHHGHNIK_00530 3.8e-190 asnA 6.3.1.1 F aspartate--ammonia ligase
FHHGHNIK_00531 1.9e-218 steT_1 E amino acid
FHHGHNIK_00532 2.7e-21 puuD S peptidase C26
FHHGHNIK_00533 2.8e-244 yifK E Amino acid permease
FHHGHNIK_00534 3.2e-211 cycA E Amino acid permease
FHHGHNIK_00535 1.2e-127
FHHGHNIK_00536 3.9e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
FHHGHNIK_00537 0.0 clpE O AAA domain (Cdc48 subfamily)
FHHGHNIK_00538 1.7e-156 S Alpha/beta hydrolase of unknown function (DUF915)
FHHGHNIK_00539 9.9e-209 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FHHGHNIK_00540 7e-21 XK27_06785 V ABC transporter, ATP-binding protein
FHHGHNIK_00541 3.5e-94 XK27_06785 V ABC transporter, ATP-binding protein
FHHGHNIK_00542 2.5e-112 XK27_06780 V ABC transporter permease
FHHGHNIK_00543 3.6e-99 L PFAM Integrase catalytic region
FHHGHNIK_00544 1.4e-65
FHHGHNIK_00545 1.8e-23
FHHGHNIK_00546 1.6e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
FHHGHNIK_00547 5.2e-41 S RelB antitoxin
FHHGHNIK_00548 4.6e-12
FHHGHNIK_00549 8.3e-26 ybbH_2 K rpiR family
FHHGHNIK_00550 1.1e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
FHHGHNIK_00551 4.8e-159 yeaE S Aldo/keto reductase family
FHHGHNIK_00552 2.2e-97 S ECF transporter, substrate-specific component
FHHGHNIK_00553 0.0 macB_3 V ABC transporter, ATP-binding protein
FHHGHNIK_00554 3.8e-196 S DUF218 domain
FHHGHNIK_00555 1.5e-118 S CAAX protease self-immunity
FHHGHNIK_00556 1.6e-45
FHHGHNIK_00557 5.9e-152 mutR K Helix-turn-helix XRE-family like proteins
FHHGHNIK_00558 1.8e-78 S Putative adhesin
FHHGHNIK_00559 2.1e-280 V ABC transporter transmembrane region
FHHGHNIK_00560 1.6e-47 S YoeB-like toxin of bacterial type II toxin-antitoxin system
FHHGHNIK_00561 4.4e-49 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
FHHGHNIK_00562 1.7e-202 napA P Sodium/hydrogen exchanger family
FHHGHNIK_00563 0.0 cadA P P-type ATPase
FHHGHNIK_00564 3.9e-81 ykuL S (CBS) domain
FHHGHNIK_00565 2e-211 ywhK S Membrane
FHHGHNIK_00566 3.8e-50
FHHGHNIK_00567 4.5e-18 S D-Ala-teichoic acid biosynthesis protein
FHHGHNIK_00568 3.1e-289 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FHHGHNIK_00569 2.9e-240 dltB M MBOAT, membrane-bound O-acyltransferase family
FHHGHNIK_00570 5.7e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FHHGHNIK_00571 9.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FHHGHNIK_00572 4.6e-174 pbpX2 V Beta-lactamase
FHHGHNIK_00574 1.5e-10
FHHGHNIK_00575 2.5e-71 S CAAX protease self-immunity
FHHGHNIK_00576 9.6e-16
FHHGHNIK_00577 6.1e-120 S Protein of unknown function (DUF975)
FHHGHNIK_00578 1.6e-145 lysA2 M Glycosyl hydrolases family 25
FHHGHNIK_00579 1.1e-284 ytgP S Polysaccharide biosynthesis protein
FHHGHNIK_00580 3.3e-36
FHHGHNIK_00581 1.8e-94 XK27_06780 V ABC transporter permease
FHHGHNIK_00582 7.3e-11
FHHGHNIK_00583 1.7e-31
FHHGHNIK_00584 1e-37 S Asp23 family, cell envelope-related function
FHHGHNIK_00587 1.8e-195 ampC V Beta-lactamase
FHHGHNIK_00588 2.8e-22 EGP Major facilitator Superfamily
FHHGHNIK_00589 2.1e-107 EGP Major facilitator Superfamily
FHHGHNIK_00590 1.2e-34 EGP Major facilitator Superfamily
FHHGHNIK_00591 6e-260 pgi 5.3.1.9 G Belongs to the GPI family
FHHGHNIK_00592 2.5e-104 vanZ V VanZ like family
FHHGHNIK_00593 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
FHHGHNIK_00594 5.3e-270 yclK 2.7.13.3 T Histidine kinase
FHHGHNIK_00595 5.9e-129 K Transcriptional regulatory protein, C terminal
FHHGHNIK_00596 5.4e-60 S SdpI/YhfL protein family
FHHGHNIK_00597 1.9e-167 manA 5.3.1.8 G mannose-6-phosphate isomerase
FHHGHNIK_00598 6.6e-72 patB 4.4.1.8 E Aminotransferase, class I
FHHGHNIK_00599 2e-61 patB 4.4.1.8 E Aminotransferase, class I
FHHGHNIK_00600 1.5e-58 patB 4.4.1.8 E Aminotransferase, class I
FHHGHNIK_00601 4e-31 M Protein of unknown function (DUF3737)
FHHGHNIK_00602 1.3e-33 M Protein of unknown function (DUF3737)
FHHGHNIK_00604 9.7e-09 K transcriptional
FHHGHNIK_00606 2.1e-15
FHHGHNIK_00607 1e-18 S Membrane
FHHGHNIK_00609 5e-18
FHHGHNIK_00610 1.1e-31 sip L Belongs to the 'phage' integrase family
FHHGHNIK_00611 3.4e-44 S Phage integrase family
FHHGHNIK_00613 5.7e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FHHGHNIK_00614 1e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
FHHGHNIK_00615 1.9e-81 comGF U Putative Competence protein ComGF
FHHGHNIK_00616 3.9e-41
FHHGHNIK_00617 6.1e-73
FHHGHNIK_00618 1.1e-43 comGC U competence protein ComGC
FHHGHNIK_00619 8.4e-174 comGB NU type II secretion system
FHHGHNIK_00620 2.5e-175 comGA NU Type II IV secretion system protein
FHHGHNIK_00621 2.6e-132 yebC K Transcriptional regulatory protein
FHHGHNIK_00622 3.2e-84 S VanZ like family
FHHGHNIK_00623 1.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FHHGHNIK_00624 1.1e-295 E Amino acid permease
FHHGHNIK_00625 1.7e-39 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
FHHGHNIK_00626 2.4e-118 XK27_07525 3.6.1.55 F NUDIX domain
FHHGHNIK_00627 3.5e-132 2.4.2.3 F Phosphorylase superfamily
FHHGHNIK_00628 4.9e-75 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
FHHGHNIK_00630 6.1e-79 K Acetyltransferase (GNAT) domain
FHHGHNIK_00631 2.2e-54
FHHGHNIK_00632 5.4e-135
FHHGHNIK_00633 5.7e-206 EGP Major facilitator Superfamily
FHHGHNIK_00634 1.7e-102
FHHGHNIK_00635 3.2e-55 S Fic/DOC family
FHHGHNIK_00636 4e-30 S Fic/DOC family
FHHGHNIK_00637 1.7e-56
FHHGHNIK_00638 6.8e-73
FHHGHNIK_00639 1.3e-58 ypaA S Protein of unknown function (DUF1304)
FHHGHNIK_00640 9.2e-69 S Putative adhesin
FHHGHNIK_00641 3.4e-294 V ABC-type multidrug transport system, ATPase and permease components
FHHGHNIK_00642 2.2e-293 P ABC transporter
FHHGHNIK_00643 5.3e-59
FHHGHNIK_00644 5.5e-33
FHHGHNIK_00645 1.9e-255 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
FHHGHNIK_00646 8.7e-235 mepA V MATE efflux family protein
FHHGHNIK_00647 1.5e-230 S Putative peptidoglycan binding domain
FHHGHNIK_00648 6.9e-93 S ECF-type riboflavin transporter, S component
FHHGHNIK_00649 8.2e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
FHHGHNIK_00650 2.9e-204 pbpX1 V Beta-lactamase
FHHGHNIK_00651 1.8e-104 lacA 2.3.1.79 S Transferase hexapeptide repeat
FHHGHNIK_00652 5.2e-113 3.6.1.27 I Acid phosphatase homologues
FHHGHNIK_00653 1.8e-75 C Flavodoxin
FHHGHNIK_00654 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
FHHGHNIK_00655 1e-54 ktrB P Potassium uptake protein
FHHGHNIK_00656 7.9e-246 ynbB 4.4.1.1 P aluminum resistance
FHHGHNIK_00657 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
FHHGHNIK_00658 1.4e-158 L An automated process has identified a potential problem with this gene model
FHHGHNIK_00659 3.6e-271 E Amino acid permease
FHHGHNIK_00660 1.5e-15 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
FHHGHNIK_00661 1.8e-27 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
FHHGHNIK_00662 1.1e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FHHGHNIK_00663 2.8e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FHHGHNIK_00664 1.7e-148 xerD L Phage integrase, N-terminal SAM-like domain
FHHGHNIK_00665 7.1e-36 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
FHHGHNIK_00666 6e-84 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
FHHGHNIK_00667 2.8e-13 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
FHHGHNIK_00668 4.2e-108 accA 2.1.3.15, 6.4.1.2 I alpha subunit
FHHGHNIK_00669 1.1e-69 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FHHGHNIK_00673 1.5e-174 lacX 5.1.3.3 G Aldose 1-epimerase
FHHGHNIK_00674 1.7e-233 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FHHGHNIK_00675 3e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FHHGHNIK_00676 1.6e-168 xerC D Phage integrase, N-terminal SAM-like domain
FHHGHNIK_00677 1.2e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FHHGHNIK_00678 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FHHGHNIK_00679 2.8e-154 dprA LU DNA protecting protein DprA
FHHGHNIK_00680 3.7e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FHHGHNIK_00681 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FHHGHNIK_00682 9.9e-278 yjcE P Sodium proton antiporter
FHHGHNIK_00683 9.3e-36 yozE S Belongs to the UPF0346 family
FHHGHNIK_00684 7.7e-149 DegV S Uncharacterised protein, DegV family COG1307
FHHGHNIK_00685 9.7e-113 hlyIII S protein, hemolysin III
FHHGHNIK_00686 1.1e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FHHGHNIK_00687 1.4e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHHGHNIK_00688 1.9e-228 S Tetratricopeptide repeat protein
FHHGHNIK_00689 8.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FHHGHNIK_00690 2.8e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
FHHGHNIK_00691 5.3e-207 rpsA 1.17.7.4 J Ribosomal protein S1
FHHGHNIK_00692 5e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
FHHGHNIK_00693 9.1e-30 yocH M Lysin motif
FHHGHNIK_00694 4.6e-115 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FHHGHNIK_00695 5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FHHGHNIK_00696 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FHHGHNIK_00697 1.2e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FHHGHNIK_00698 4.9e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FHHGHNIK_00699 4e-167 xerD D recombinase XerD
FHHGHNIK_00700 1.4e-167 cvfB S S1 domain
FHHGHNIK_00701 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
FHHGHNIK_00702 6.6e-184 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
FHHGHNIK_00703 0.0 dnaE 2.7.7.7 L DNA polymerase
FHHGHNIK_00704 1.2e-21 S Protein of unknown function (DUF2929)
FHHGHNIK_00705 1.7e-298 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
FHHGHNIK_00706 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
FHHGHNIK_00707 6.2e-33 yrvD S Lipopolysaccharide assembly protein A domain
FHHGHNIK_00708 1.1e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
FHHGHNIK_00709 3.9e-173 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
FHHGHNIK_00710 0.0 oatA I Acyltransferase
FHHGHNIK_00711 7.2e-242 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FHHGHNIK_00712 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
FHHGHNIK_00713 7.5e-43 dedA 3.1.3.1 S SNARE associated Golgi protein
FHHGHNIK_00714 1.1e-240 yfnA E Amino Acid
FHHGHNIK_00715 1.1e-41 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHHGHNIK_00716 4.8e-74 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHHGHNIK_00717 7.8e-16 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHHGHNIK_00718 3.4e-141 yxeH S hydrolase
FHHGHNIK_00719 2.4e-133 S reductase
FHHGHNIK_00720 4e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FHHGHNIK_00721 1.6e-219 patA 2.6.1.1 E Aminotransferase
FHHGHNIK_00722 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
FHHGHNIK_00723 1.1e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
FHHGHNIK_00724 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
FHHGHNIK_00725 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FHHGHNIK_00726 2.5e-59
FHHGHNIK_00727 2.7e-174 prmA J Ribosomal protein L11 methyltransferase
FHHGHNIK_00728 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FHHGHNIK_00729 9.4e-34 M domain protein
FHHGHNIK_00730 6.6e-41
FHHGHNIK_00731 1.2e-76 yxkA S Phosphatidylethanolamine-binding protein
FHHGHNIK_00732 6.7e-243 yjjP S Putative threonine/serine exporter
FHHGHNIK_00733 6.3e-171 citR K Putative sugar-binding domain
FHHGHNIK_00734 4.7e-16
FHHGHNIK_00735 2.2e-66 S Domain of unknown function DUF1828
FHHGHNIK_00736 3.6e-94 S UPF0397 protein
FHHGHNIK_00737 5.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
FHHGHNIK_00738 9.4e-86 uspA T universal stress protein
FHHGHNIK_00739 5.6e-148 phnD P Phosphonate ABC transporter
FHHGHNIK_00740 1.3e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FHHGHNIK_00741 6.5e-129 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
FHHGHNIK_00742 2.4e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
FHHGHNIK_00743 1.1e-106 tag 3.2.2.20 L glycosylase
FHHGHNIK_00744 1.6e-82
FHHGHNIK_00745 3.5e-271 S Calcineurin-like phosphoesterase
FHHGHNIK_00746 0.0 asnB 6.3.5.4 E Asparagine synthase
FHHGHNIK_00747 3.6e-254 yxbA 6.3.1.12 S ATP-grasp enzyme
FHHGHNIK_00748 2.4e-13 3.6.3.2, 3.6.3.6 P cation transport ATPase
FHHGHNIK_00749 6.2e-186 3.6.3.6 P Cation transporter/ATPase, N-terminus
FHHGHNIK_00750 6.3e-73 3.6.3.6 P Cation transporter/ATPase, N-terminus
FHHGHNIK_00751 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
FHHGHNIK_00752 9.6e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FHHGHNIK_00753 3.3e-98 S Iron-sulfur cluster assembly protein
FHHGHNIK_00754 1.5e-225 XK27_04775 S PAS domain
FHHGHNIK_00755 7.4e-225 yttB EGP Major facilitator Superfamily
FHHGHNIK_00756 0.0 pepO 3.4.24.71 O Peptidase family M13
FHHGHNIK_00757 0.0 kup P Transport of potassium into the cell
FHHGHNIK_00758 4.5e-71
FHHGHNIK_00760 5.2e-19
FHHGHNIK_00761 8.9e-38 S Protein of unknown function (DUF2922)
FHHGHNIK_00762 2.9e-180 S SLAP domain
FHHGHNIK_00764 1.6e-32 L COG2963 Transposase and inactivated derivatives
FHHGHNIK_00765 9.4e-33 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FHHGHNIK_00766 1.2e-80 racA K Domain of unknown function (DUF1836)
FHHGHNIK_00767 1.2e-152 yitS S EDD domain protein, DegV family
FHHGHNIK_00769 2.4e-22 dnaX 2.4.99.16, 2.7.7.7 GH13 M domain protein
FHHGHNIK_00770 2.5e-80 dnaX 2.4.99.16, 2.7.7.7 GH13 M domain protein
FHHGHNIK_00771 9.2e-136 mdcD 4.1.1.87 I Malonate decarboxylase gamma subunit (MdcE)
FHHGHNIK_00772 3.4e-115 mdcG 2.7.7.66 H Phosphoribosyl-dephospho-CoA transferase MdcG
FHHGHNIK_00773 8.5e-137 yisY 1.11.1.10 S Alpha/beta hydrolase family
FHHGHNIK_00774 8.4e-148 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
FHHGHNIK_00775 1.7e-41
FHHGHNIK_00776 4e-136 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
FHHGHNIK_00777 9.7e-124 mgtC S MgtC family
FHHGHNIK_00778 2.5e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FHHGHNIK_00779 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
FHHGHNIK_00780 9.4e-56 yheA S Belongs to the UPF0342 family
FHHGHNIK_00781 5.3e-231 yhaO L Ser Thr phosphatase family protein
FHHGHNIK_00782 0.0 L AAA domain
FHHGHNIK_00783 4.2e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
FHHGHNIK_00784 2.3e-50 S PAS domain
FHHGHNIK_00785 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
FHHGHNIK_00786 8e-28
FHHGHNIK_00787 1.2e-79 hit FG Scavenger mRNA decapping enzyme C-term binding
FHHGHNIK_00788 5.5e-42 S Plasmid maintenance system killer
FHHGHNIK_00789 8.4e-54 higA K Helix-turn-helix XRE-family like proteins
FHHGHNIK_00790 8.8e-136 ecsA V ABC transporter, ATP-binding protein
FHHGHNIK_00791 8.9e-215 ecsB U ABC transporter
FHHGHNIK_00792 2.6e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
FHHGHNIK_00793 1.1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
FHHGHNIK_00794 4.1e-121 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FHHGHNIK_00795 1.7e-259
FHHGHNIK_00796 2.8e-193 L Transposase and inactivated derivatives, IS30 family
FHHGHNIK_00797 1.2e-17 S protein conserved in bacteria
FHHGHNIK_00798 6.2e-78 2.7.7.12 C Domain of unknown function (DUF4931)
FHHGHNIK_00799 1.5e-120
FHHGHNIK_00800 8.4e-142 S Belongs to the UPF0246 family
FHHGHNIK_00801 5.4e-141 aroD S Alpha/beta hydrolase family
FHHGHNIK_00802 3.6e-111 G phosphoglycerate mutase
FHHGHNIK_00803 4.1e-95 ygfC K Bacterial regulatory proteins, tetR family
FHHGHNIK_00804 2e-165 hrtB V ABC transporter permease
FHHGHNIK_00805 8.8e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
FHHGHNIK_00806 1.5e-274 pipD E Dipeptidase
FHHGHNIK_00807 6.8e-37
FHHGHNIK_00808 9.1e-110 K WHG domain
FHHGHNIK_00809 2.1e-94 nqr 1.5.1.36 S NADPH-dependent FMN reductase
FHHGHNIK_00810 5.9e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
FHHGHNIK_00811 3.7e-148 3.1.3.48 T Tyrosine phosphatase family
FHHGHNIK_00812 2e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
FHHGHNIK_00813 1.6e-83 cvpA S Colicin V production protein
FHHGHNIK_00814 2.7e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
FHHGHNIK_00815 1.5e-147 noc K Belongs to the ParB family
FHHGHNIK_00816 9.2e-136 soj D Sporulation initiation inhibitor
FHHGHNIK_00817 7.7e-155 spo0J K Belongs to the ParB family
FHHGHNIK_00818 3.7e-44 yyzM S Bacterial protein of unknown function (DUF951)
FHHGHNIK_00819 8e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
FHHGHNIK_00820 4.6e-135 XK27_01040 S Protein of unknown function (DUF1129)
FHHGHNIK_00821 2.8e-294 V ABC transporter, ATP-binding protein
FHHGHNIK_00822 0.0 V ABC transporter
FHHGHNIK_00823 5.1e-122 K response regulator
FHHGHNIK_00824 2e-208 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
FHHGHNIK_00825 8.8e-303 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FHHGHNIK_00826 1.7e-142 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
FHHGHNIK_00827 1.5e-213 S Archaea bacterial proteins of unknown function
FHHGHNIK_00828 2.9e-10 S Enterocin A Immunity
FHHGHNIK_00829 4.8e-54 S Enterocin A Immunity
FHHGHNIK_00830 8.5e-32 S Uncharacterised protein family (UPF0236)
FHHGHNIK_00831 5e-18 brnQ E Component of the transport system for branched-chain amino acids
FHHGHNIK_00832 8.6e-15 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FHHGHNIK_00833 1.6e-147 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FHHGHNIK_00834 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
FHHGHNIK_00835 2.3e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FHHGHNIK_00836 4.9e-179 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FHHGHNIK_00837 4.4e-24
FHHGHNIK_00838 8.6e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FHHGHNIK_00839 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
FHHGHNIK_00840 1.2e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FHHGHNIK_00841 7.7e-134 comFC S Competence protein
FHHGHNIK_00842 9.5e-247 comFA L Helicase C-terminal domain protein
FHHGHNIK_00843 5.3e-116 yvyE 3.4.13.9 S YigZ family
FHHGHNIK_00844 4.2e-209 tagO 2.7.8.33, 2.7.8.35 M transferase
FHHGHNIK_00845 4e-218 rny S Endoribonuclease that initiates mRNA decay
FHHGHNIK_00846 4.7e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FHHGHNIK_00847 1.9e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FHHGHNIK_00848 4.2e-134 ymfM S Helix-turn-helix domain
FHHGHNIK_00849 6.8e-133 IQ Enoyl-(Acyl carrier protein) reductase
FHHGHNIK_00850 6.9e-234 S Peptidase M16
FHHGHNIK_00851 2.8e-224 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
FHHGHNIK_00852 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
FHHGHNIK_00853 1.6e-67 WQ51_03320 S Protein of unknown function (DUF1149)
FHHGHNIK_00854 2.7e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
FHHGHNIK_00855 1.8e-191 yubA S AI-2E family transporter
FHHGHNIK_00856 3.9e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
FHHGHNIK_00857 3.7e-48 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
FHHGHNIK_00858 1.2e-34 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
FHHGHNIK_00862 2e-43 S membrane transporter protein
FHHGHNIK_00863 5e-13 S membrane transporter protein
FHHGHNIK_00864 6.1e-83 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
FHHGHNIK_00865 2.7e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
FHHGHNIK_00866 2.7e-61 S Protein of unknown function (DUF805)
FHHGHNIK_00867 4.6e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
FHHGHNIK_00868 1.7e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FHHGHNIK_00869 2.8e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
FHHGHNIK_00870 2.6e-138 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FHHGHNIK_00871 4e-150 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FHHGHNIK_00872 1.3e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FHHGHNIK_00873 1.1e-60 rplQ J Ribosomal protein L17
FHHGHNIK_00874 1.5e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FHHGHNIK_00875 5.2e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FHHGHNIK_00876 2.1e-55 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FHHGHNIK_00877 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
FHHGHNIK_00878 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FHHGHNIK_00879 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
FHHGHNIK_00880 2.2e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
FHHGHNIK_00881 5.9e-71 rplO J Binds to the 23S rRNA
FHHGHNIK_00882 2.3e-24 rpmD J Ribosomal protein L30
FHHGHNIK_00883 1.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FHHGHNIK_00884 2.8e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FHHGHNIK_00885 4.7e-91 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FHHGHNIK_00886 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FHHGHNIK_00887 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FHHGHNIK_00888 3.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FHHGHNIK_00889 9.8e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FHHGHNIK_00890 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FHHGHNIK_00891 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FHHGHNIK_00892 3.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
FHHGHNIK_00893 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FHHGHNIK_00894 1.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FHHGHNIK_00895 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FHHGHNIK_00896 1.6e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FHHGHNIK_00897 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FHHGHNIK_00898 1.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
FHHGHNIK_00899 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
FHHGHNIK_00900 9.9e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FHHGHNIK_00901 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
FHHGHNIK_00902 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FHHGHNIK_00903 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
FHHGHNIK_00904 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FHHGHNIK_00905 2.3e-122 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
FHHGHNIK_00906 0.0 ydgH S MMPL family
FHHGHNIK_00907 3.3e-98 yobS K Bacterial regulatory proteins, tetR family
FHHGHNIK_00908 6.8e-157 3.5.2.6 V Beta-lactamase enzyme family
FHHGHNIK_00909 2.9e-157 corA P CorA-like Mg2+ transporter protein
FHHGHNIK_00910 4.3e-231 G Bacterial extracellular solute-binding protein
FHHGHNIK_00911 5.6e-255 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
FHHGHNIK_00912 4.7e-146 gtsC P Binding-protein-dependent transport system inner membrane component
FHHGHNIK_00913 3.6e-157 gtsB P ABC-type sugar transport systems, permease components
FHHGHNIK_00914 5.6e-200 malK P ATPases associated with a variety of cellular activities
FHHGHNIK_00915 1.9e-280 pipD E Dipeptidase
FHHGHNIK_00916 1.6e-157 endA F DNA RNA non-specific endonuclease
FHHGHNIK_00917 7e-162 dnaQ 2.7.7.7 L EXOIII
FHHGHNIK_00918 5.3e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FHHGHNIK_00919 1.4e-105 yviA S Protein of unknown function (DUF421)
FHHGHNIK_00920 2.9e-63 S Protein of unknown function (DUF3290)
FHHGHNIK_00921 8.4e-139 pnuC H nicotinamide mononucleotide transporter
FHHGHNIK_00922 3.1e-93 S PAS domain
FHHGHNIK_00923 1.2e-275 V ABC transporter transmembrane region
FHHGHNIK_00924 2.7e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
FHHGHNIK_00925 1.9e-186 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FHHGHNIK_00926 1.3e-95 F Nucleoside 2-deoxyribosyltransferase
FHHGHNIK_00927 3.3e-67 S Peptidase propeptide and YPEB domain
FHHGHNIK_00928 6.9e-34 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
FHHGHNIK_00929 6.1e-43 M1-431 S Protein of unknown function (DUF1706)
FHHGHNIK_00930 6.7e-21 M1-431 S Protein of unknown function (DUF1706)
FHHGHNIK_00932 2.2e-138
FHHGHNIK_00933 1e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
FHHGHNIK_00934 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
FHHGHNIK_00935 9.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
FHHGHNIK_00936 4.1e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FHHGHNIK_00937 4.2e-152 ydjP I Alpha/beta hydrolase family
FHHGHNIK_00938 6.3e-271 P Sodium:sulfate symporter transmembrane region
FHHGHNIK_00939 8.8e-256 pepC 3.4.22.40 E Peptidase C1-like family
FHHGHNIK_00940 1.4e-45
FHHGHNIK_00941 1.1e-73 fhaB M Rib/alpha-like repeat
FHHGHNIK_00942 2.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
FHHGHNIK_00944 1.6e-109 M domain protein
FHHGHNIK_00945 2e-263 frdC 1.3.5.4 C FAD binding domain
FHHGHNIK_00946 1.3e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
FHHGHNIK_00947 2.5e-26
FHHGHNIK_00948 9.3e-64 S cog cog1373
FHHGHNIK_00949 1.8e-84 S cog cog1373
FHHGHNIK_00950 2.8e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FHHGHNIK_00951 2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
FHHGHNIK_00952 4.2e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
FHHGHNIK_00953 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FHHGHNIK_00954 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FHHGHNIK_00955 2e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FHHGHNIK_00956 1.7e-34 yaaA S S4 domain protein YaaA
FHHGHNIK_00957 3.9e-196 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
FHHGHNIK_00958 3.8e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FHHGHNIK_00959 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
FHHGHNIK_00960 6e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
FHHGHNIK_00961 2.1e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FHHGHNIK_00962 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FHHGHNIK_00963 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
FHHGHNIK_00964 6.3e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FHHGHNIK_00965 6.1e-280 clcA P chloride
FHHGHNIK_00966 5.7e-208
FHHGHNIK_00967 1.3e-17
FHHGHNIK_00968 4.2e-46 S CAAX protease self-immunity
FHHGHNIK_00969 2.4e-184 lacR K Transcriptional regulator
FHHGHNIK_00970 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
FHHGHNIK_00971 4.1e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
FHHGHNIK_00972 1.8e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
FHHGHNIK_00973 5.5e-149
FHHGHNIK_00974 1.5e-161
FHHGHNIK_00975 4.8e-133
FHHGHNIK_00976 7.5e-263 glnA 6.3.1.2 E glutamine synthetase
FHHGHNIK_00977 1.3e-131 ynbB 4.4.1.1 P aluminum resistance
FHHGHNIK_00978 9.7e-25 ynbB 4.4.1.1 P aluminum resistance
FHHGHNIK_00979 1.3e-168 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FHHGHNIK_00980 5e-69 yqhL P Rhodanese-like protein
FHHGHNIK_00981 1.2e-32 yqgQ S Bacterial protein of unknown function (DUF910)
FHHGHNIK_00982 3.5e-115 gluP 3.4.21.105 S Rhomboid family
FHHGHNIK_00983 1.6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FHHGHNIK_00984 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
FHHGHNIK_00985 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
FHHGHNIK_00986 6.3e-168 S membrane
FHHGHNIK_00987 6.5e-293 S membrane
FHHGHNIK_00988 4.4e-169 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
FHHGHNIK_00989 5.3e-69 infB UW LPXTG-motif cell wall anchor domain protein
FHHGHNIK_00990 1.6e-23 infB UW LPXTG-motif cell wall anchor domain protein
FHHGHNIK_00991 2.4e-19 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
FHHGHNIK_00992 4.7e-13 UW LPXTG-motif cell wall anchor domain protein
FHHGHNIK_00993 5.6e-21
FHHGHNIK_00994 1.4e-59 CO Thioredoxin
FHHGHNIK_00995 1.8e-113 M1-798 K Rhodanese Homology Domain
FHHGHNIK_00996 3.5e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
FHHGHNIK_00997 1.1e-36 frnE Q DSBA-like thioredoxin domain
FHHGHNIK_00998 1.2e-33 frnE Q DSBA-like thioredoxin domain
FHHGHNIK_00999 2.7e-30 3.6.4.12 S PD-(D/E)XK nuclease family transposase
FHHGHNIK_01000 1.3e-137 yxeH S hydrolase
FHHGHNIK_01001 4.2e-37 S Enterocin A Immunity
FHHGHNIK_01002 1.3e-39 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
FHHGHNIK_01003 2.9e-48 pspC KT PspC domain
FHHGHNIK_01005 4.2e-242 dacA 3.4.16.4 M Belongs to the peptidase S11 family
FHHGHNIK_01006 1.1e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FHHGHNIK_01007 5.7e-110 M ErfK YbiS YcfS YnhG
FHHGHNIK_01008 3.7e-88 padR K Virulence activator alpha C-term
FHHGHNIK_01009 8.3e-102 padC Q Phenolic acid decarboxylase
FHHGHNIK_01010 2.5e-112 3.6.4.12 S PD-(D/E)XK nuclease family transposase
FHHGHNIK_01011 2.1e-12 3.6.4.12 S PD-(D/E)XK nuclease family transposase
FHHGHNIK_01012 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
FHHGHNIK_01013 1e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
FHHGHNIK_01014 6e-91 3.6.1.55 L NUDIX domain
FHHGHNIK_01015 3.1e-38
FHHGHNIK_01016 3.2e-29
FHHGHNIK_01017 8e-161 S ABC transporter
FHHGHNIK_01018 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
FHHGHNIK_01019 3e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
FHHGHNIK_01020 6.3e-125 S Haloacid dehalogenase-like hydrolase
FHHGHNIK_01021 2.1e-114 radC L DNA repair protein
FHHGHNIK_01022 4.6e-172 mreB D cell shape determining protein MreB
FHHGHNIK_01023 2e-144 mreC M Involved in formation and maintenance of cell shape
FHHGHNIK_01024 3.8e-96 mreD
FHHGHNIK_01025 6.5e-13 S Protein of unknown function (DUF4044)
FHHGHNIK_01026 1.4e-53 S Protein of unknown function (DUF3397)
FHHGHNIK_01027 9.1e-77 mraZ K Belongs to the MraZ family
FHHGHNIK_01028 2e-183 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
FHHGHNIK_01029 5.5e-51 ftsL D Cell division protein FtsL
FHHGHNIK_01030 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
FHHGHNIK_01031 3e-176 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FHHGHNIK_01032 4.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FHHGHNIK_01033 1.4e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FHHGHNIK_01034 1.1e-129 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
FHHGHNIK_01035 8.8e-235 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
FHHGHNIK_01036 1.6e-204 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FHHGHNIK_01037 1.4e-72 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
FHHGHNIK_01038 2.2e-45 yggT S YGGT family
FHHGHNIK_01039 1.4e-147 ylmH S S4 domain protein
FHHGHNIK_01040 9.2e-99 gpsB D DivIVA domain protein
FHHGHNIK_01041 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FHHGHNIK_01042 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
FHHGHNIK_01043 1.3e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
FHHGHNIK_01044 2.5e-36
FHHGHNIK_01045 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FHHGHNIK_01046 1e-215 iscS 2.8.1.7 E Aminotransferase class V
FHHGHNIK_01047 1.4e-56 XK27_04120 S Putative amino acid metabolism
FHHGHNIK_01048 1.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
FHHGHNIK_01049 4.7e-125 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
FHHGHNIK_01050 1.1e-102 S Repeat protein
FHHGHNIK_01051 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
FHHGHNIK_01052 5.6e-18 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
FHHGHNIK_01053 9.4e-78 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
FHHGHNIK_01054 2.3e-29 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
FHHGHNIK_01055 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FHHGHNIK_01056 4.2e-33 ykzG S Belongs to the UPF0356 family
FHHGHNIK_01057 7.6e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FHHGHNIK_01058 0.0 typA T GTP-binding protein TypA
FHHGHNIK_01059 5.4e-204 ftsW D Belongs to the SEDS family
FHHGHNIK_01060 7.3e-53 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
FHHGHNIK_01061 1.1e-95 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
FHHGHNIK_01062 8e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FHHGHNIK_01063 1.9e-192 ylbL T Belongs to the peptidase S16 family
FHHGHNIK_01064 1.1e-82 comEA L Competence protein ComEA
FHHGHNIK_01065 0.0 comEC S Competence protein ComEC
FHHGHNIK_01066 2e-172 holA 2.7.7.7 L DNA polymerase III delta subunit
FHHGHNIK_01067 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
FHHGHNIK_01068 7e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FHHGHNIK_01069 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FHHGHNIK_01070 8.3e-151
FHHGHNIK_01071 2.3e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FHHGHNIK_01072 1.7e-206 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
FHHGHNIK_01073 2.3e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FHHGHNIK_01074 5.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
FHHGHNIK_01075 4.6e-205 yjeM E Amino Acid
FHHGHNIK_01076 5.6e-59 yjeM E Amino Acid
FHHGHNIK_01077 9.2e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FHHGHNIK_01078 5.2e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
FHHGHNIK_01079 2.7e-249 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
FHHGHNIK_01080 6.1e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
FHHGHNIK_01081 5.8e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
FHHGHNIK_01082 8.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FHHGHNIK_01083 1.3e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
FHHGHNIK_01084 6.5e-210 aspC 2.6.1.1 E Aminotransferase
FHHGHNIK_01085 2e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FHHGHNIK_01086 6.5e-204 pbpX1 V Beta-lactamase
FHHGHNIK_01087 9.7e-112 3.6.1.55 F NUDIX domain
FHHGHNIK_01088 1.5e-294 I Protein of unknown function (DUF2974)
FHHGHNIK_01089 1.7e-15 C FMN_bind
FHHGHNIK_01090 1.4e-08
FHHGHNIK_01091 6.1e-55
FHHGHNIK_01092 5e-173 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
FHHGHNIK_01093 2.3e-17 S Aldo keto reductase
FHHGHNIK_01094 4.8e-102 S Aldo keto reductase
FHHGHNIK_01095 5.2e-44 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FHHGHNIK_01096 1.1e-155 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FHHGHNIK_01097 5.3e-199 ydiM G Major Facilitator Superfamily
FHHGHNIK_01098 2.2e-111 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
FHHGHNIK_01099 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
FHHGHNIK_01100 4.8e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FHHGHNIK_01101 3.9e-220 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FHHGHNIK_01102 2.5e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
FHHGHNIK_01103 3.7e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHHGHNIK_01104 2.6e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHHGHNIK_01105 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHHGHNIK_01106 1.2e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FHHGHNIK_01107 3.8e-201 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
FHHGHNIK_01108 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
FHHGHNIK_01109 4.8e-243 purD 6.3.4.13 F Belongs to the GARS family
FHHGHNIK_01110 9.5e-43 S PAS domain
FHHGHNIK_01111 3.7e-107 pncA Q Isochorismatase family
FHHGHNIK_01112 6.4e-268 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FHHGHNIK_01113 3e-125 3.6.1.13, 3.6.1.55 F NUDIX domain
FHHGHNIK_01115 2.1e-72 S Iron-sulphur cluster biosynthesis
FHHGHNIK_01116 1.5e-37 K Helix-turn-helix domain
FHHGHNIK_01117 4e-57 S Phage derived protein Gp49-like (DUF891)
FHHGHNIK_01118 6.3e-168 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
FHHGHNIK_01119 4.1e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FHHGHNIK_01120 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FHHGHNIK_01121 9e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FHHGHNIK_01122 6.7e-62 yodB K Transcriptional regulator, HxlR family
FHHGHNIK_01123 5.7e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHHGHNIK_01124 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
FHHGHNIK_01125 1.1e-154 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FHHGHNIK_01126 2.5e-83 S Aminoacyl-tRNA editing domain
FHHGHNIK_01127 3.7e-277 arlS 2.7.13.3 T Histidine kinase
FHHGHNIK_01128 7.2e-127 K response regulator
FHHGHNIK_01129 1e-96 yceD S Uncharacterized ACR, COG1399
FHHGHNIK_01130 3.3e-214 ylbM S Belongs to the UPF0348 family
FHHGHNIK_01131 4.5e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
FHHGHNIK_01132 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
FHHGHNIK_01133 2.4e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FHHGHNIK_01134 9.5e-211 yqeH S Ribosome biogenesis GTPase YqeH
FHHGHNIK_01135 3.8e-93 yqeG S HAD phosphatase, family IIIA
FHHGHNIK_01136 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FHHGHNIK_01137 2e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
FHHGHNIK_01138 4.8e-55 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FHHGHNIK_01139 1.3e-160 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
FHHGHNIK_01140 8.5e-27 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
FHHGHNIK_01141 6.2e-22 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FHHGHNIK_01142 2.6e-66 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FHHGHNIK_01143 2.2e-41 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FHHGHNIK_01144 1.2e-88 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FHHGHNIK_01145 1.8e-28 licT K CAT RNA binding domain
FHHGHNIK_01146 7.8e-216 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
FHHGHNIK_01147 4.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FHHGHNIK_01148 1.4e-114
FHHGHNIK_01149 6.2e-24 S Sucrose-6F-phosphate phosphohydrolase
FHHGHNIK_01150 1.9e-88 S Sucrose-6F-phosphate phosphohydrolase
FHHGHNIK_01151 4.4e-149 S hydrolase
FHHGHNIK_01152 2.6e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FHHGHNIK_01153 8.3e-171 ybbR S YbbR-like protein
FHHGHNIK_01154 1.2e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FHHGHNIK_01155 1.1e-203 potD P ABC transporter
FHHGHNIK_01156 6.5e-124 potC P ABC transporter permease
FHHGHNIK_01157 5.1e-129 potB P ABC transporter permease
FHHGHNIK_01158 2.9e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
FHHGHNIK_01159 7e-164 murB 1.3.1.98 M Cell wall formation
FHHGHNIK_01160 1.4e-98 dnaQ 2.7.7.7 L DNA polymerase III
FHHGHNIK_01161 1.9e-89 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
FHHGHNIK_01162 5.5e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
FHHGHNIK_01163 2e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FHHGHNIK_01164 9.7e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
FHHGHNIK_01165 1.8e-95
FHHGHNIK_01166 6.7e-218 S SLAP domain
FHHGHNIK_01167 3.9e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FHHGHNIK_01168 2.5e-148 GK ROK family
FHHGHNIK_01169 5.5e-43
FHHGHNIK_01170 3.6e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
FHHGHNIK_01171 1.4e-66 S Domain of unknown function (DUF1934)
FHHGHNIK_01172 3.9e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
FHHGHNIK_01173 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
FHHGHNIK_01174 2.8e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FHHGHNIK_01175 3.7e-33 S Haloacid dehalogenase-like hydrolase
FHHGHNIK_01176 4.4e-49 S Haloacid dehalogenase-like hydrolase
FHHGHNIK_01177 6.3e-284 pipD E Dipeptidase
FHHGHNIK_01178 9e-158 msmR K AraC-like ligand binding domain
FHHGHNIK_01179 9.7e-215 pbuX F xanthine permease
FHHGHNIK_01180 5.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
FHHGHNIK_01181 1.7e-113 K DNA-binding helix-turn-helix protein
FHHGHNIK_01182 1.1e-20 K Helix-turn-helix
FHHGHNIK_01183 2.4e-16 K Helix-turn-helix
FHHGHNIK_01184 1.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
FHHGHNIK_01185 3.6e-35
FHHGHNIK_01187 1.4e-10
FHHGHNIK_01188 1.3e-109 L transposase, IS605 OrfB family
FHHGHNIK_01189 4.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FHHGHNIK_01190 1.3e-151 glnH ET ABC transporter substrate-binding protein
FHHGHNIK_01191 3e-108 gluC P ABC transporter permease
FHHGHNIK_01192 1.7e-106 glnP P ABC transporter permease
FHHGHNIK_01193 5.6e-75 S Protein of unknown function (DUF2974)
FHHGHNIK_01194 3.3e-63 S Protein of unknown function (DUF2974)
FHHGHNIK_01195 8.6e-101 S SLAP domain
FHHGHNIK_01196 1e-235 G Bacterial extracellular solute-binding protein
FHHGHNIK_01197 7.2e-160 2.7.7.12 C Domain of unknown function (DUF4931)
FHHGHNIK_01198 1.9e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FHHGHNIK_01199 1.5e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FHHGHNIK_01200 0.0 kup P Transport of potassium into the cell
FHHGHNIK_01201 2e-174 rihB 3.2.2.1 F Nucleoside
FHHGHNIK_01202 4e-133 gntR K UbiC transcription regulator-associated domain protein
FHHGHNIK_01203 2.8e-135 S hydrolase
FHHGHNIK_01204 2e-103 pflC 1.97.1.4 O Radical SAM superfamily
FHHGHNIK_01206 1.1e-31 tdh 1.1.1.14 C Zinc-binding dehydrogenase
FHHGHNIK_01207 3.3e-95 tdh 1.1.1.14 C Zinc-binding dehydrogenase
FHHGHNIK_01208 1.1e-16
FHHGHNIK_01210 3.5e-43 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
FHHGHNIK_01211 5.2e-108 ubiX 2.5.1.129, 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
FHHGHNIK_01213 2.5e-08 K PFAM Bacterial regulatory helix-turn-helix protein, lysR family
FHHGHNIK_01214 5.8e-72 S Protein of unknown function (DUF554)
FHHGHNIK_01215 4.2e-240 brnQ U Component of the transport system for branched-chain amino acids
FHHGHNIK_01216 5.4e-47
FHHGHNIK_01217 1.2e-155 malY 4.4.1.8 E Aminotransferase, class I
FHHGHNIK_01218 2.5e-36
FHHGHNIK_01219 8e-102 S LexA-binding, inner membrane-associated putative hydrolase
FHHGHNIK_01220 1.1e-15
FHHGHNIK_01222 3.6e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
FHHGHNIK_01223 1.4e-257 S C4-dicarboxylate anaerobic carrier
FHHGHNIK_01224 1.9e-23
FHHGHNIK_01225 4.1e-45
FHHGHNIK_01226 5.3e-64
FHHGHNIK_01227 1.8e-13
FHHGHNIK_01228 1.9e-100 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
FHHGHNIK_01229 6e-22 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
FHHGHNIK_01230 2.4e-13 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
FHHGHNIK_01231 8e-12 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
FHHGHNIK_01232 9.3e-239 N Uncharacterized conserved protein (DUF2075)
FHHGHNIK_01233 5.4e-39 mmuP E amino acid
FHHGHNIK_01234 1.6e-144 mmuP E amino acid
FHHGHNIK_01235 3.4e-61 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
FHHGHNIK_01236 1.3e-12 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
FHHGHNIK_01237 1.9e-30 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
FHHGHNIK_01238 1e-58 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
FHHGHNIK_01239 2.7e-17
FHHGHNIK_01240 3.5e-62
FHHGHNIK_01241 2.1e-14 S Peptidase propeptide and YPEB domain
FHHGHNIK_01243 5.9e-120 yfbR S HD containing hydrolase-like enzyme
FHHGHNIK_01244 1.2e-157 L HNH nucleases
FHHGHNIK_01245 3.6e-137 glnQ E ABC transporter, ATP-binding protein
FHHGHNIK_01246 3.5e-291 glnP P ABC transporter permease
FHHGHNIK_01247 3e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
FHHGHNIK_01248 4.1e-62 yeaO S Protein of unknown function, DUF488
FHHGHNIK_01249 9e-123 terC P Integral membrane protein TerC family
FHHGHNIK_01250 1.3e-90 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
FHHGHNIK_01251 1.5e-129 cobB K SIR2 family
FHHGHNIK_01252 6.6e-84
FHHGHNIK_01253 1.4e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHHGHNIK_01254 9.8e-177 S Alpha/beta hydrolase of unknown function (DUF915)
FHHGHNIK_01255 2.1e-145 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FHHGHNIK_01256 1.6e-137 ypuA S Protein of unknown function (DUF1002)
FHHGHNIK_01257 4e-158 epsV 2.7.8.12 S glycosyl transferase family 2
FHHGHNIK_01258 1.8e-124 S Alpha/beta hydrolase family
FHHGHNIK_01259 3.3e-115 GM NmrA-like family
FHHGHNIK_01260 0.0 clpE O Belongs to the ClpA ClpB family
FHHGHNIK_01261 3.3e-26
FHHGHNIK_01262 8.5e-41 ptsH G phosphocarrier protein HPR
FHHGHNIK_01263 4.2e-306 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FHHGHNIK_01264 2.3e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
FHHGHNIK_01265 1.8e-133 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
FHHGHNIK_01266 1.2e-157 coiA 3.6.4.12 S Competence protein
FHHGHNIK_01267 7.3e-112 yjbH Q Thioredoxin
FHHGHNIK_01268 4.3e-112 yjbK S CYTH
FHHGHNIK_01269 2.1e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
FHHGHNIK_01270 3.9e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FHHGHNIK_01271 5.2e-167 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FHHGHNIK_01272 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
FHHGHNIK_01273 4.1e-41 S SNARE associated Golgi protein
FHHGHNIK_01274 1.4e-55 S SNARE associated Golgi protein
FHHGHNIK_01275 1.2e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
FHHGHNIK_01276 4.7e-40 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
FHHGHNIK_01277 1e-48 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
FHHGHNIK_01278 2.5e-44 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
FHHGHNIK_01279 1.7e-232 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
FHHGHNIK_01280 5.8e-32 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
FHHGHNIK_01281 3.9e-69 S Iron-sulphur cluster biosynthesis
FHHGHNIK_01282 1.4e-190 ybiR P Citrate transporter
FHHGHNIK_01283 2.3e-96 lemA S LemA family
FHHGHNIK_01284 1.5e-161 htpX O Belongs to the peptidase M48B family
FHHGHNIK_01285 5.6e-111 L Helix-turn-helix domain
FHHGHNIK_01286 1.9e-164 L hmm pf00665
FHHGHNIK_01287 3.3e-172 K helix_turn_helix, arabinose operon control protein
FHHGHNIK_01288 9.8e-236 cbiO1 S ABC transporter, ATP-binding protein
FHHGHNIK_01289 9.9e-91 P Cobalt transport protein
FHHGHNIK_01290 5.7e-174 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
FHHGHNIK_01291 1.6e-76 S SLAP domain
FHHGHNIK_01292 1e-96 S Bacteriocin helveticin-J
FHHGHNIK_01293 3.5e-60 apt 2.4.2.7 F Phosphoribosyl transferase domain
FHHGHNIK_01294 3.7e-151 P secondary active sulfate transmembrane transporter activity
FHHGHNIK_01295 8.2e-65 L Transposase DDE domain
FHHGHNIK_01296 1.4e-30 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
FHHGHNIK_01297 1.6e-76 S Domain of unknown function (DUF4430)
FHHGHNIK_01298 7.9e-183 U FFAT motif binding
FHHGHNIK_01299 0.0 S Domain of unknown function (DUF4430)
FHHGHNIK_01301 1.9e-153 P ABC-type cobalt transport system permease component CbiQ and related transporters
FHHGHNIK_01302 0.0 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
FHHGHNIK_01303 8.7e-125 S ECF-type riboflavin transporter, S component
FHHGHNIK_01304 3.9e-44 scrK 2.7.1.2, 2.7.1.4 GK ROK family
FHHGHNIK_01305 7.8e-174 degV S DegV family
FHHGHNIK_01306 2.8e-163 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
FHHGHNIK_01307 2.5e-253 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
FHHGHNIK_01308 1.1e-67 rplI J Binds to the 23S rRNA
FHHGHNIK_01309 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
FHHGHNIK_01310 8.1e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FHHGHNIK_01311 1.1e-131 yitS S Uncharacterised protein, DegV family COG1307
FHHGHNIK_01312 2.3e-99 3.6.1.27 I Acid phosphatase homologues
FHHGHNIK_01313 1.9e-54 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
FHHGHNIK_01314 6.1e-56 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
FHHGHNIK_01316 1.2e-61 S PFAM Uncharacterised protein family UPF0150
FHHGHNIK_01317 1.4e-16 yifK E Amino acid permease
FHHGHNIK_01318 1.4e-157 yifK E Amino acid permease
FHHGHNIK_01319 5.5e-37 yifK E Amino acid permease
FHHGHNIK_01320 4.5e-185 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FHHGHNIK_01321 6.8e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FHHGHNIK_01322 7.2e-16 ps301 K sequence-specific DNA binding
FHHGHNIK_01323 0.0 aha1 P E1-E2 ATPase
FHHGHNIK_01324 2.8e-162 metQ1 P Belongs to the nlpA lipoprotein family
FHHGHNIK_01325 1.6e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FHHGHNIK_01326 1.2e-86 metI P ABC transporter permease
FHHGHNIK_01327 1.3e-273 pepV 3.5.1.18 E dipeptidase PepV
FHHGHNIK_01328 7e-189 V Beta-lactamase
FHHGHNIK_01329 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FHHGHNIK_01330 8.4e-54 K HxlR-like helix-turn-helix
FHHGHNIK_01331 3.5e-115
FHHGHNIK_01332 7.6e-73
FHHGHNIK_01333 1.4e-28
FHHGHNIK_01334 8.9e-12
FHHGHNIK_01335 1.2e-103
FHHGHNIK_01336 5e-86
FHHGHNIK_01337 4.9e-111 L COG3547 Transposase and inactivated derivatives
FHHGHNIK_01338 6.6e-72
FHHGHNIK_01339 2.7e-88 XK27_09675 K Acetyltransferase (GNAT) domain
FHHGHNIK_01340 4e-53 S Protein of unknown function (DUF3021)
FHHGHNIK_01341 1e-75 K LytTr DNA-binding domain
FHHGHNIK_01342 7.2e-43
FHHGHNIK_01343 4.4e-123 magIII L Base excision DNA repair protein, HhH-GPD family
FHHGHNIK_01344 5.8e-26 folT S ECF transporter, substrate-specific component
FHHGHNIK_01345 6.5e-57 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FHHGHNIK_01346 8.6e-201 folE 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 F GTP cyclohydrolase 1
FHHGHNIK_01347 4.2e-245 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
FHHGHNIK_01348 1.4e-198 folP 2.5.1.15 H dihydropteroate synthase
FHHGHNIK_01349 1.7e-96 3.6.1.55, 3.6.1.67 F NUDIX domain
FHHGHNIK_01350 2.7e-73 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
FHHGHNIK_01351 8.6e-57 adhR K helix_turn_helix, mercury resistance
FHHGHNIK_01352 6e-112 papP P ABC transporter, permease protein
FHHGHNIK_01353 2.6e-86 P ABC transporter permease
FHHGHNIK_01354 1.6e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FHHGHNIK_01355 9.1e-161 cjaA ET ABC transporter substrate-binding protein
FHHGHNIK_01356 6.6e-16
FHHGHNIK_01357 2e-39 S SpoVT / AbrB like domain
FHHGHNIK_01358 1.8e-50 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
FHHGHNIK_01359 1.2e-16 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
FHHGHNIK_01360 1.7e-204 malE G Bacterial extracellular solute-binding protein
FHHGHNIK_01361 4.6e-252 gor 1.8.1.7 C Glutathione reductase
FHHGHNIK_01362 2.8e-88 K Acetyltransferase (GNAT) family
FHHGHNIK_01363 1.3e-69 S Alpha beta hydrolase
FHHGHNIK_01364 1.6e-67 S Hydrolases of the alpha beta superfamily
FHHGHNIK_01365 2.5e-59 S Hydrolases of the alpha beta superfamily
FHHGHNIK_01366 6.4e-142 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
FHHGHNIK_01367 2e-28 1.1.1.3 T phosphoserine phosphatase activity
FHHGHNIK_01368 8.2e-66 XK27_08635 S UPF0210 protein
FHHGHNIK_01369 1e-30 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FHHGHNIK_01370 4.2e-131 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
FHHGHNIK_01371 1.4e-14 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
FHHGHNIK_01372 4.4e-94 K acetyltransferase
FHHGHNIK_01373 5.8e-85 dps P Belongs to the Dps family
FHHGHNIK_01374 1.1e-20
FHHGHNIK_01375 6.6e-31
FHHGHNIK_01376 1.6e-17 snf 2.7.11.1 KL domain protein
FHHGHNIK_01377 6.2e-38 snf 2.7.11.1 KL domain protein
FHHGHNIK_01378 8.1e-242 snf 2.7.11.1 KL domain protein
FHHGHNIK_01379 6.7e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
FHHGHNIK_01380 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FHHGHNIK_01381 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FHHGHNIK_01382 1.9e-170 K Transcriptional regulator
FHHGHNIK_01383 1.3e-163 ppaC 3.6.1.1 C inorganic pyrophosphatase
FHHGHNIK_01384 2.2e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FHHGHNIK_01385 6.2e-55 K Helix-turn-helix domain
FHHGHNIK_01386 2.9e-100 yoaK S Protein of unknown function (DUF1275)
FHHGHNIK_01387 2.4e-13 ytgB S Transglycosylase associated protein
FHHGHNIK_01388 4.9e-144 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
FHHGHNIK_01389 4.3e-31 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
FHHGHNIK_01390 3.8e-78 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
FHHGHNIK_01391 2.1e-79 marR K Transcriptional regulator
FHHGHNIK_01392 9.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FHHGHNIK_01393 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
FHHGHNIK_01394 1.7e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
FHHGHNIK_01395 1.9e-127 IQ reductase
FHHGHNIK_01396 2.8e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FHHGHNIK_01397 3.1e-78 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
FHHGHNIK_01398 3.8e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
FHHGHNIK_01399 4.7e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
FHHGHNIK_01400 6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FHHGHNIK_01401 1.2e-143 accA 2.1.3.15, 6.4.1.2 I alpha subunit
FHHGHNIK_01402 4.9e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
FHHGHNIK_01403 2.6e-188 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
FHHGHNIK_01404 1.3e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FHHGHNIK_01405 2.6e-80 S An automated process has identified a potential problem with this gene model
FHHGHNIK_01406 6.5e-140 S Protein of unknown function (DUF3100)
FHHGHNIK_01407 8.8e-245 S amidohydrolase
FHHGHNIK_01409 2.8e-57 3.6.4.12 S PD-(D/E)XK nuclease family transposase
FHHGHNIK_01410 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FHHGHNIK_01411 1.2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
FHHGHNIK_01412 5e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FHHGHNIK_01413 9.2e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FHHGHNIK_01414 2.2e-246 dnaB L Replication initiation and membrane attachment
FHHGHNIK_01415 9.9e-166 dnaI L Primosomal protein DnaI
FHHGHNIK_01416 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FHHGHNIK_01419 1.5e-288 lsa S ABC transporter
FHHGHNIK_01420 1.5e-17
FHHGHNIK_01421 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FHHGHNIK_01422 1.9e-74 S Protein of unknown function (DUF3021)
FHHGHNIK_01423 6.6e-75 K LytTr DNA-binding domain
FHHGHNIK_01424 1.4e-104 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
FHHGHNIK_01427 0.0 uvrA3 L excinuclease ABC, A subunit
FHHGHNIK_01428 1.4e-92 yyaR K Acetyltransferase (GNAT) domain
FHHGHNIK_01429 1.5e-101 mta K helix_turn_helix, mercury resistance
FHHGHNIK_01430 5.3e-07 S ParE toxin of type II toxin-antitoxin system, parDE
FHHGHNIK_01431 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
FHHGHNIK_01432 9.5e-80 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FHHGHNIK_01433 5e-157 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FHHGHNIK_01434 7.4e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FHHGHNIK_01435 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
FHHGHNIK_01436 0.0 FbpA K Fibronectin-binding protein
FHHGHNIK_01437 3.9e-39
FHHGHNIK_01438 3.3e-158 degV S EDD domain protein, DegV family
FHHGHNIK_01439 7.6e-205 xerS L Belongs to the 'phage' integrase family
FHHGHNIK_01440 3.2e-19 S protein conserved in bacteria
FHHGHNIK_01441 3.2e-29 S protein conserved in bacteria
FHHGHNIK_01442 1e-69 S Iron-sulphur cluster biosynthesis
FHHGHNIK_01443 5.6e-12
FHHGHNIK_01444 3e-63
FHHGHNIK_01445 2.9e-170 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
FHHGHNIK_01446 1.6e-260 S Archaea bacterial proteins of unknown function
FHHGHNIK_01447 9.6e-13
FHHGHNIK_01448 1.3e-94 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FHHGHNIK_01449 2.1e-107 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FHHGHNIK_01450 4.7e-160 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHHGHNIK_01451 4.4e-57 M LysM domain protein
FHHGHNIK_01452 2.8e-196 D nuclear chromosome segregation
FHHGHNIK_01453 4.9e-110 G Phosphoglycerate mutase family
FHHGHNIK_01454 3.1e-101 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
FHHGHNIK_01455 6.2e-117 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
FHHGHNIK_01456 3.4e-95 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FHHGHNIK_01457 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
FHHGHNIK_01458 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
FHHGHNIK_01459 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
FHHGHNIK_01460 3.1e-82 S Short repeat of unknown function (DUF308)
FHHGHNIK_01461 6.9e-164 rapZ S Displays ATPase and GTPase activities
FHHGHNIK_01462 1.3e-193 ybhK S Required for morphogenesis under gluconeogenic growth conditions
FHHGHNIK_01463 2.2e-168 whiA K May be required for sporulation
FHHGHNIK_01464 8.8e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
FHHGHNIK_01465 1.7e-19 I alpha/beta hydrolase fold
FHHGHNIK_01466 2.9e-129 yibF S overlaps another CDS with the same product name
FHHGHNIK_01467 8.2e-202 yibE S overlaps another CDS with the same product name
FHHGHNIK_01468 7.2e-90
FHHGHNIK_01469 2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
FHHGHNIK_01470 4.3e-228 S Cysteine-rich secretory protein family
FHHGHNIK_01471 5.8e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FHHGHNIK_01472 1.3e-260 glnPH2 P ABC transporter permease
FHHGHNIK_01473 2.2e-127
FHHGHNIK_01474 8.2e-120 luxT K Bacterial regulatory proteins, tetR family
FHHGHNIK_01475 1.6e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FHHGHNIK_01476 6.8e-30
FHHGHNIK_01477 1.3e-176 1.6.5.5 C Zinc-binding dehydrogenase
FHHGHNIK_01478 5.3e-150 larE S NAD synthase
FHHGHNIK_01479 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
FHHGHNIK_01480 2.5e-74 larC 4.99.1.12 S Protein of unknown function DUF111
FHHGHNIK_01481 1.4e-131 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FHHGHNIK_01482 2e-124 larB S AIR carboxylase
FHHGHNIK_01483 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
FHHGHNIK_01484 4.2e-121 K Crp-like helix-turn-helix domain
FHHGHNIK_01485 2.4e-181 nikMN P PDGLE domain
FHHGHNIK_01486 8.4e-148 P Cobalt transport protein
FHHGHNIK_01487 3.3e-127 cbiO P ABC transporter
FHHGHNIK_01488 1.4e-39
FHHGHNIK_01489 3.7e-96 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
FHHGHNIK_01490 1.9e-125 M NlpC P60 family protein
FHHGHNIK_01491 1.7e-136 M NlpC/P60 family
FHHGHNIK_01492 1.1e-199 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FHHGHNIK_01493 2.7e-178 brpA K Cell envelope-like function transcriptional attenuator common domain protein
FHHGHNIK_01494 1.4e-140 epsB M biosynthesis protein
FHHGHNIK_01495 1.8e-118 ywqD 2.7.10.1 D Capsular exopolysaccharide family
FHHGHNIK_01496 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
FHHGHNIK_01497 2.2e-122 rfbP M Bacterial sugar transferase
FHHGHNIK_01498 5.2e-83 cpsF M Oligosaccharide biosynthesis protein Alg14 like
FHHGHNIK_01499 8.6e-79 pssE S Glycosyltransferase family 28 C-terminal domain
FHHGHNIK_01500 8e-102 M Glycosyltransferase sugar-binding region containing DXD motif
FHHGHNIK_01501 1.4e-295 ytgP S Polysaccharide biosynthesis protein
FHHGHNIK_01502 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
FHHGHNIK_01503 3.9e-119 3.6.1.27 I Acid phosphatase homologues
FHHGHNIK_01504 7e-149 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
FHHGHNIK_01505 1.2e-258 qacA EGP Major facilitator Superfamily
FHHGHNIK_01506 1.6e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FHHGHNIK_01509 1.4e-167 psaA P Belongs to the bacterial solute-binding protein 9 family
FHHGHNIK_01511 2.5e-107 S Peptidase family M23
FHHGHNIK_01512 3.7e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
FHHGHNIK_01513 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
FHHGHNIK_01514 9.4e-69 yqeY S YqeY-like protein
FHHGHNIK_01515 8e-174 phoH T phosphate starvation-inducible protein PhoH
FHHGHNIK_01516 8.5e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FHHGHNIK_01517 2.8e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FHHGHNIK_01518 5.2e-136 recO L Involved in DNA repair and RecF pathway recombination
FHHGHNIK_01519 6.1e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
FHHGHNIK_01520 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
FHHGHNIK_01521 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
FHHGHNIK_01522 1e-196 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
FHHGHNIK_01523 2.2e-122 S Peptidase family M23
FHHGHNIK_01524 3.6e-68 mutT 3.6.1.55 F NUDIX domain
FHHGHNIK_01525 3.2e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
FHHGHNIK_01526 2.6e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FHHGHNIK_01527 3.4e-241 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
FHHGHNIK_01528 3.9e-60 yvoA_1 K Transcriptional regulator, GntR family
FHHGHNIK_01529 1.1e-122 skfE V ATPases associated with a variety of cellular activities
FHHGHNIK_01530 4e-145
FHHGHNIK_01531 1.7e-143
FHHGHNIK_01532 5.6e-130
FHHGHNIK_01533 2.3e-33 rarA L recombination factor protein RarA
FHHGHNIK_01534 1.4e-104 rarA L recombination factor protein RarA
FHHGHNIK_01535 2.9e-27
FHHGHNIK_01536 1.2e-103 lepB 3.4.21.89 U Belongs to the peptidase S26 family
FHHGHNIK_01537 1.5e-138
FHHGHNIK_01538 8.2e-174
FHHGHNIK_01539 1.2e-258 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
FHHGHNIK_01540 4.1e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
FHHGHNIK_01541 1.2e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
FHHGHNIK_01542 7.5e-180 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
FHHGHNIK_01543 2.6e-166 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
FHHGHNIK_01544 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
FHHGHNIK_01545 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
FHHGHNIK_01546 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
FHHGHNIK_01547 2.4e-89 ypmB S Protein conserved in bacteria
FHHGHNIK_01548 1.2e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
FHHGHNIK_01549 7.4e-115 dnaD L DnaD domain protein
FHHGHNIK_01550 3.9e-113 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FHHGHNIK_01551 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
FHHGHNIK_01552 2.3e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
FHHGHNIK_01553 7.2e-106 ypsA S Belongs to the UPF0398 family
FHHGHNIK_01554 3e-69 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
FHHGHNIK_01555 6.2e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
FHHGHNIK_01556 1.3e-69 cpdA S Calcineurin-like phosphoesterase
FHHGHNIK_01557 5e-88 cpdA S Calcineurin-like phosphoesterase
FHHGHNIK_01558 2.8e-32
FHHGHNIK_01559 3.5e-106 K LysR substrate binding domain
FHHGHNIK_01560 2.5e-19
FHHGHNIK_01561 5.8e-211 S Sterol carrier protein domain
FHHGHNIK_01562 3.4e-97 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
FHHGHNIK_01563 5.2e-77 arcC 2.7.2.2 E Belongs to the carbamate kinase family
FHHGHNIK_01564 6.9e-69 arcC 2.7.2.2 E Belongs to the carbamate kinase family
FHHGHNIK_01565 5.7e-141 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FHHGHNIK_01566 1.9e-90 arcA 3.5.3.6 E Arginine
FHHGHNIK_01567 1.5e-47 arcA 3.5.3.6 E Arginine
FHHGHNIK_01568 3.2e-26 arcA 3.5.3.6 E Arginine
FHHGHNIK_01569 1.8e-156 lysR5 K LysR substrate binding domain
FHHGHNIK_01570 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
FHHGHNIK_01571 2.4e-84 3.4.21.96 S SLAP domain
FHHGHNIK_01572 1.1e-40 S Enterocin A Immunity
FHHGHNIK_01573 2.8e-70 lctP C L-lactate permease
FHHGHNIK_01574 3.2e-232 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FHHGHNIK_01575 1.6e-127 znuB U ABC 3 transport family
FHHGHNIK_01576 1.9e-115 fhuC P ABC transporter
FHHGHNIK_01577 4.2e-156 psaA P Belongs to the bacterial solute-binding protein 9 family
FHHGHNIK_01578 1.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
FHHGHNIK_01579 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
FHHGHNIK_01580 3.1e-167 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
FHHGHNIK_01581 1.3e-140 fruR K DeoR C terminal sensor domain
FHHGHNIK_01582 3.8e-254 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
FHHGHNIK_01584 3.3e-62 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
FHHGHNIK_01585 2.2e-160 P CorA-like Mg2+ transporter protein
FHHGHNIK_01588 5.3e-167 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FHHGHNIK_01589 1.2e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
FHHGHNIK_01590 4.2e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
FHHGHNIK_01591 1.5e-56 S SLAP domain
FHHGHNIK_01592 5.7e-105 EGP Major facilitator Superfamily
FHHGHNIK_01594 4e-22 EGP Major facilitator Superfamily
FHHGHNIK_01595 3.7e-96 ropB K Transcriptional regulator
FHHGHNIK_01597 5.5e-21
FHHGHNIK_01598 6.9e-16 metQ_4 P Belongs to the nlpA lipoprotein family
FHHGHNIK_01599 2.7e-28 IQ reductase
FHHGHNIK_01600 1.4e-43 IQ reductase
FHHGHNIK_01601 1.6e-193 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FHHGHNIK_01602 2.7e-73 nrdI F Probably involved in ribonucleotide reductase function
FHHGHNIK_01603 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FHHGHNIK_01605 3.3e-222 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FHHGHNIK_01606 6.5e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
FHHGHNIK_01607 7.7e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
FHHGHNIK_01608 1e-79 K response regulator
FHHGHNIK_01609 6.1e-63 sptS 2.7.13.3 T Histidine kinase
FHHGHNIK_01610 1.3e-115 sptS 2.7.13.3 T Histidine kinase
FHHGHNIK_01611 2.3e-207 EGP Major facilitator Superfamily
FHHGHNIK_01612 1.6e-70 O OsmC-like protein
FHHGHNIK_01613 6.6e-125 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
FHHGHNIK_01614 3.9e-78
FHHGHNIK_01615 1.3e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
FHHGHNIK_01616 1.1e-96 rpiR1 K Helix-turn-helix domain, rpiR family
FHHGHNIK_01617 1.4e-47 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FHHGHNIK_01618 1.6e-43 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FHHGHNIK_01619 3.6e-141 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
FHHGHNIK_01620 6.5e-18 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
FHHGHNIK_01621 7.7e-32 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
FHHGHNIK_01622 1.1e-41 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
FHHGHNIK_01623 2.4e-215 naiP EGP Major facilitator Superfamily
FHHGHNIK_01624 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
FHHGHNIK_01625 8.8e-09 oppA E ABC transporter
FHHGHNIK_01626 1e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
FHHGHNIK_01627 9.9e-247 XK27_08635 S UPF0210 protein
FHHGHNIK_01628 8.6e-41 gcvR T Belongs to the UPF0237 family
FHHGHNIK_01629 5.9e-124 lacZ 3.2.1.23 G -beta-galactosidase
FHHGHNIK_01630 3.3e-34 lacZ 3.2.1.23 G -beta-galactosidase
FHHGHNIK_01631 0.0 lacS G Transporter
FHHGHNIK_01632 1.2e-141 lacS G Transporter
FHHGHNIK_01633 4.9e-46 lacS G Transporter
FHHGHNIK_01634 2.1e-24 lacS G Transporter
FHHGHNIK_01635 9.8e-51 K DNA-templated transcription, initiation
FHHGHNIK_01636 2.3e-100
FHHGHNIK_01637 2.6e-217 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FHHGHNIK_01638 3.7e-207 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
FHHGHNIK_01639 0.0 yjbQ P TrkA C-terminal domain protein
FHHGHNIK_01640 4.7e-131 gepA K Protein of unknown function (DUF4065)
FHHGHNIK_01641 6.4e-179 S Oxidoreductase family, NAD-binding Rossmann fold
FHHGHNIK_01642 3.7e-45
FHHGHNIK_01643 8.8e-22 ropB K Transcriptional regulator
FHHGHNIK_01645 2.4e-100
FHHGHNIK_01646 4.3e-20 K Helix-turn-helix XRE-family like proteins
FHHGHNIK_01648 3.9e-59 speG J Acetyltransferase (GNAT) domain
FHHGHNIK_01650 4.6e-61 L Transposase DDE domain
FHHGHNIK_01651 2.2e-67 L Transposase DDE domain
FHHGHNIK_01656 6.6e-41 repA S Replication initiator protein A
FHHGHNIK_01657 1.2e-19 2.7.7.12 C Domain of unknown function (DUF4931)
FHHGHNIK_01658 6.1e-179 S Putative peptidoglycan binding domain
FHHGHNIK_01659 1.5e-23
FHHGHNIK_01660 5.5e-188 dtpT U amino acid peptide transporter
FHHGHNIK_01661 1.3e-32 dtpT U amino acid peptide transporter
FHHGHNIK_01662 0.0 pepN 3.4.11.2 E aminopeptidase
FHHGHNIK_01664 2.5e-59 lysM M LysM domain
FHHGHNIK_01665 9.4e-170
FHHGHNIK_01666 5.2e-213 mdtG EGP Major facilitator Superfamily
FHHGHNIK_01667 0.0 uup S ABC transporter, ATP-binding protein
FHHGHNIK_01668 1.7e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FHHGHNIK_01669 4.3e-77 XK27_02470 K LytTr DNA-binding domain
FHHGHNIK_01670 2.5e-122 liaI S membrane
FHHGHNIK_01671 2.5e-178 scrR K Transcriptional regulator, LacI family
FHHGHNIK_01672 9.8e-141 scrB 3.2.1.26 GH32 G invertase
FHHGHNIK_01673 2.3e-87 scrB 3.2.1.26 GH32 G invertase
FHHGHNIK_01674 9.8e-46 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
FHHGHNIK_01675 1.1e-145 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
FHHGHNIK_01676 5.6e-130 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
FHHGHNIK_01677 1.4e-45
FHHGHNIK_01678 4.7e-91
FHHGHNIK_01679 3e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FHHGHNIK_01680 9.7e-289 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
FHHGHNIK_01681 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FHHGHNIK_01682 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FHHGHNIK_01683 3.5e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
FHHGHNIK_01684 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
FHHGHNIK_01685 1.1e-37 yajC U Preprotein translocase
FHHGHNIK_01686 4.9e-284 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FHHGHNIK_01687 7.1e-214 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FHHGHNIK_01688 6.7e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
FHHGHNIK_01689 5.2e-235 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
FHHGHNIK_01690 1.4e-64
FHHGHNIK_01691 4.9e-87
FHHGHNIK_01692 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FHHGHNIK_01693 2e-42 yrzL S Belongs to the UPF0297 family
FHHGHNIK_01694 1e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FHHGHNIK_01695 2.4e-50 yrzB S Belongs to the UPF0473 family
FHHGHNIK_01696 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FHHGHNIK_01697 4.6e-54 trxA O Belongs to the thioredoxin family
FHHGHNIK_01698 2.2e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
FHHGHNIK_01699 8.5e-69 yslB S Protein of unknown function (DUF2507)
FHHGHNIK_01700 7e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
FHHGHNIK_01701 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FHHGHNIK_01702 4.1e-153 ykuT M mechanosensitive ion channel
FHHGHNIK_01703 3.3e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FHHGHNIK_01704 3e-44
FHHGHNIK_01705 5.4e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
FHHGHNIK_01706 1.2e-180 ccpA K catabolite control protein A
FHHGHNIK_01707 6.3e-265 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FHHGHNIK_01708 1.1e-55
FHHGHNIK_01709 1.1e-275 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
FHHGHNIK_01710 8.4e-84 yutD S Protein of unknown function (DUF1027)
FHHGHNIK_01711 1.2e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
FHHGHNIK_01712 2.2e-84 S Protein of unknown function (DUF1461)
FHHGHNIK_01713 2e-115 dedA S SNARE-like domain protein
FHHGHNIK_01714 2.9e-148 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
FHHGHNIK_01715 0.0 V FtsX-like permease family
FHHGHNIK_01716 1.4e-133 cysA V ABC transporter, ATP-binding protein
FHHGHNIK_01717 7.5e-236 S response to antibiotic
FHHGHNIK_01718 7e-124
FHHGHNIK_01719 3.2e-15
FHHGHNIK_01720 4.7e-185 ansA 3.5.1.1 EJ L-asparaginase, type I
FHHGHNIK_01721 5.7e-130 glvR K Helix-turn-helix domain, rpiR family
FHHGHNIK_01722 1.9e-266 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
FHHGHNIK_01723 8.5e-86 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
FHHGHNIK_01725 3.6e-18 M domain protein
FHHGHNIK_01726 8e-34 M domain protein
FHHGHNIK_01727 5e-212 M domain protein
FHHGHNIK_01728 7.9e-105 L Transposase
FHHGHNIK_01729 4.3e-118 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
FHHGHNIK_01730 1.7e-229 amd 3.5.1.47 E Peptidase family M20/M25/M40
FHHGHNIK_01731 7.1e-229 steT E amino acid
FHHGHNIK_01732 3.3e-59 pdxH S Pyridoxamine 5'-phosphate oxidase
FHHGHNIK_01733 2.6e-149 cbiO2 P ABC transporter
FHHGHNIK_01734 4.3e-155 P ABC transporter
FHHGHNIK_01735 8.2e-132 cbiQ P Cobalt transport protein
FHHGHNIK_01736 7.2e-88 2.7.7.65 T phosphorelay sensor kinase activity
FHHGHNIK_01737 8.7e-171 wbbI M transferase activity, transferring glycosyl groups
FHHGHNIK_01738 4e-193 glf 5.4.99.9 M UDP-galactopyranose mutase
FHHGHNIK_01739 3.3e-92 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHHGHNIK_01740 1.9e-150 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
FHHGHNIK_01741 0.0 traA L MobA MobL family protein
FHHGHNIK_01742 1.3e-69 doc S Fic/DOC family
FHHGHNIK_01743 2.6e-34
FHHGHNIK_01744 1.8e-150 S Fic/DOC family
FHHGHNIK_01745 1.9e-104 L Resolvase, N terminal domain
FHHGHNIK_01746 8.7e-210 V ABC transporter transmembrane region
FHHGHNIK_01748 7.8e-69 K Helix-turn-helix XRE-family like proteins
FHHGHNIK_01749 3.7e-91 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FHHGHNIK_01750 2.8e-179 htrA 3.4.21.107 O serine protease
FHHGHNIK_01751 7.4e-149 vicX 3.1.26.11 S domain protein
FHHGHNIK_01752 7.7e-149 yycI S YycH protein
FHHGHNIK_01753 1.2e-239 yycH S YycH protein
FHHGHNIK_01754 1.7e-292 vicK 2.7.13.3 T Histidine kinase
FHHGHNIK_01755 2.2e-131 K response regulator
FHHGHNIK_01756 9.1e-229 pbuG S permease
FHHGHNIK_01757 4.8e-48 K helix_turn_helix, mercury resistance
FHHGHNIK_01758 7e-59 K helix_turn_helix, mercury resistance
FHHGHNIK_01759 1.9e-201 S cog cog1373
FHHGHNIK_01760 1.7e-230 pbuG S permease
FHHGHNIK_01761 2.5e-144 cof S haloacid dehalogenase-like hydrolase
FHHGHNIK_01762 4.5e-126 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
FHHGHNIK_01763 3.9e-116 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
FHHGHNIK_01764 2.8e-20 ybbH_2 K rpiR family
FHHGHNIK_01765 1.8e-21 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
FHHGHNIK_01766 1.2e-25 sprD D Domain of Unknown Function (DUF1542)
FHHGHNIK_01767 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
FHHGHNIK_01768 3.6e-160 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
FHHGHNIK_01769 3.8e-309 ybiT S ABC transporter, ATP-binding protein
FHHGHNIK_01770 1.7e-209 pepA E M42 glutamyl aminopeptidase
FHHGHNIK_01771 2.6e-175 mdtG EGP Major facilitator Superfamily
FHHGHNIK_01772 1.2e-258 emrY EGP Major facilitator Superfamily
FHHGHNIK_01773 2.3e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FHHGHNIK_01774 5.2e-240 pyrP F Permease
FHHGHNIK_01777 4e-45
FHHGHNIK_01778 2.1e-30 U Preprotein translocase subunit SecB
FHHGHNIK_01779 2e-11 S Protein of unknown function (DUF3892)
FHHGHNIK_01780 1.1e-36
FHHGHNIK_01781 4e-91 L Integrase
FHHGHNIK_01782 5.8e-43 relB L RelB antitoxin
FHHGHNIK_01783 1.2e-49 S Bacterial toxin of type II toxin-antitoxin system, YafQ
FHHGHNIK_01784 3.6e-13 J tRNA cytidylyltransferase activity
FHHGHNIK_01785 6.6e-21
FHHGHNIK_01786 7e-49 S MTH538 TIR-like domain (DUF1863)
FHHGHNIK_01787 3.3e-35
FHHGHNIK_01788 4.7e-39 L Resolvase, N terminal domain
FHHGHNIK_01789 8.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
FHHGHNIK_01790 1.1e-302 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FHHGHNIK_01791 2.5e-158 hlyX S Transporter associated domain
FHHGHNIK_01792 1.3e-73
FHHGHNIK_01793 5.4e-86
FHHGHNIK_01794 1.9e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
FHHGHNIK_01795 4.7e-260 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FHHGHNIK_01796 5.3e-80 D Alpha beta
FHHGHNIK_01797 1.9e-33 L An automated process has identified a potential problem with this gene model
FHHGHNIK_01798 2.2e-24 L An automated process has identified a potential problem with this gene model
FHHGHNIK_01799 3.6e-59 L An automated process has identified a potential problem with this gene model
FHHGHNIK_01800 6.4e-65 L An automated process has identified a potential problem with this gene model
FHHGHNIK_01801 3.8e-15
FHHGHNIK_01802 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
FHHGHNIK_01803 3.8e-117 srtA 3.4.22.70 M sortase family
FHHGHNIK_01804 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
FHHGHNIK_01805 4.1e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FHHGHNIK_01806 1.5e-112 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FHHGHNIK_01807 1.4e-10 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FHHGHNIK_01808 4.3e-149 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
FHHGHNIK_01809 6.3e-88 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHHGHNIK_01810 5.5e-145 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHHGHNIK_01812 3.2e-20 D Alpha beta
FHHGHNIK_01813 1.4e-46
FHHGHNIK_01814 5.1e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
FHHGHNIK_01815 4.3e-217 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
FHHGHNIK_01816 1.6e-213 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
FHHGHNIK_01817 6.2e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
FHHGHNIK_01818 1.2e-150 yihY S Belongs to the UPF0761 family
FHHGHNIK_01819 1.7e-164 map 3.4.11.18 E Methionine Aminopeptidase
FHHGHNIK_01820 1.6e-79 fld C Flavodoxin
FHHGHNIK_01821 4e-90 gtcA S Teichoic acid glycosylation protein
FHHGHNIK_01822 5.5e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
FHHGHNIK_01823 1.3e-25
FHHGHNIK_01825 9.2e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FHHGHNIK_01826 2.7e-206 yfmL 3.6.4.13 L DEAD DEAH box helicase
FHHGHNIK_01827 2e-129 M Glycosyl hydrolases family 25
FHHGHNIK_01828 1e-227 potE E amino acid
FHHGHNIK_01829 7e-101 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
FHHGHNIK_01830 1.3e-238 yhdP S Transporter associated domain
FHHGHNIK_01831 5e-23 C nitroreductase
FHHGHNIK_01832 2.5e-18 C nitroreductase
FHHGHNIK_01834 1.1e-83 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
FHHGHNIK_01835 1.4e-73
FHHGHNIK_01836 4.2e-22 glvR K Helix-turn-helix domain, rpiR family
FHHGHNIK_01837 8e-71 glvR K Helix-turn-helix domain, rpiR family
FHHGHNIK_01838 7.7e-308 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
FHHGHNIK_01839 2.4e-85 S hydrolase
FHHGHNIK_01840 3.3e-11 2.7.13.3 T GHKL domain
FHHGHNIK_01841 8.4e-159 rssA S Phospholipase, patatin family
FHHGHNIK_01842 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
FHHGHNIK_01843 6.8e-30
FHHGHNIK_01844 1.6e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FHHGHNIK_01845 8.2e-120 luxT K Bacterial regulatory proteins, tetR family
FHHGHNIK_01846 2.2e-127
FHHGHNIK_01847 1.3e-260 glnPH2 P ABC transporter permease
FHHGHNIK_01848 5.8e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
FHHGHNIK_01849 4.3e-228 S Cysteine-rich secretory protein family
FHHGHNIK_01850 1.9e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FHHGHNIK_01851 6.6e-96 J Acetyltransferase (GNAT) domain
FHHGHNIK_01852 5.4e-107 yjbF S SNARE associated Golgi protein
FHHGHNIK_01853 1.4e-152 I alpha/beta hydrolase fold
FHHGHNIK_01854 1e-08 hipB K Helix-turn-helix
FHHGHNIK_01855 2.9e-125 hipB K Helix-turn-helix
FHHGHNIK_01856 1.6e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
FHHGHNIK_01857 4.2e-155
FHHGHNIK_01858 8.3e-125 pgm3 G Belongs to the phosphoglycerate mutase family
FHHGHNIK_01859 2.5e-161 czcD P cation diffusion facilitator family transporter
FHHGHNIK_01860 5.5e-23
FHHGHNIK_01861 1.1e-124 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FHHGHNIK_01862 2.5e-180 S AAA domain
FHHGHNIK_01863 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
FHHGHNIK_01864 1.5e-23
FHHGHNIK_01866 8.9e-25 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
FHHGHNIK_01867 2e-18 spaB S Lantibiotic biosynthesis dehydratase C-term
FHHGHNIK_01868 6.6e-21 L Transposase
FHHGHNIK_01869 1.8e-27 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
FHHGHNIK_01870 2.7e-08
FHHGHNIK_01871 3.3e-86 D CobQ CobB MinD ParA nucleotide binding domain protein
FHHGHNIK_01873 2.3e-142 sufC O FeS assembly ATPase SufC
FHHGHNIK_01874 1.3e-200 sufD O FeS assembly protein SufD
FHHGHNIK_01875 2.1e-206 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FHHGHNIK_01876 2.7e-66 nifU C SUF system FeS assembly protein, NifU family
FHHGHNIK_01877 2.8e-268 sufB O assembly protein SufB
FHHGHNIK_01878 7.6e-44 yitW S Iron-sulfur cluster assembly protein
FHHGHNIK_01879 6.6e-231 mntH P H( )-stimulated, divalent metal cation uptake system
FHHGHNIK_01880 5.3e-42 S Archaea bacterial proteins of unknown function
FHHGHNIK_01881 4.1e-36 S Archaea bacterial proteins of unknown function
FHHGHNIK_01882 4.3e-95 M NlpC/P60 family
FHHGHNIK_01883 2.7e-94 gmk2 2.7.4.8 F Guanylate kinase homologues.
FHHGHNIK_01884 1.5e-25
FHHGHNIK_01885 2.1e-277 S O-antigen ligase like membrane protein
FHHGHNIK_01886 3.5e-93
FHHGHNIK_01887 1.2e-74 nrdI F Belongs to the NrdI family
FHHGHNIK_01888 4.9e-09 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FHHGHNIK_01889 6.9e-46
FHHGHNIK_01890 4.8e-67
FHHGHNIK_01891 1.1e-09
FHHGHNIK_01892 9.8e-149 D CobQ CobB MinD ParA nucleotide binding domain protein
FHHGHNIK_01893 2.9e-35
FHHGHNIK_01894 6.2e-18
FHHGHNIK_01895 9.2e-92 S Metallo-beta-lactamase superfamily
FHHGHNIK_01896 4.1e-67 hydD I carboxylic ester hydrolase activity
FHHGHNIK_01900 6.5e-131 pfoS S Phosphotransferase system, EIIC
FHHGHNIK_01901 2.3e-255 slpX S SLAP domain
FHHGHNIK_01902 5.2e-93
FHHGHNIK_01905 1.1e-211
FHHGHNIK_01906 4.7e-123 gntR1 K UTRA
FHHGHNIK_01907 1.8e-55 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
FHHGHNIK_01909 4.5e-131 qmcA O prohibitin homologues
FHHGHNIK_01910 5e-40 L RelB antitoxin
FHHGHNIK_01911 6e-177 S Bacteriocin helveticin-J
FHHGHNIK_01912 2.2e-48 M Peptidase family M1 domain
FHHGHNIK_01913 1.1e-30 M Peptidase family M1 domain
FHHGHNIK_01914 6.5e-117 M Peptidase family M1 domain
FHHGHNIK_01915 4.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
FHHGHNIK_01916 9.5e-65 S Psort location Cytoplasmic, score
FHHGHNIK_01918 1.3e-40 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FHHGHNIK_01919 9.1e-135 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FHHGHNIK_01920 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FHHGHNIK_01921 4.6e-245 thrC 4.2.3.1 E Threonine synthase
FHHGHNIK_01922 7.5e-120 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
FHHGHNIK_01923 2.4e-40 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
FHHGHNIK_01924 2.3e-110 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
FHHGHNIK_01925 3.5e-104
FHHGHNIK_01926 9.6e-158 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHHGHNIK_01927 1.7e-207 L Belongs to the 'phage' integrase family
FHHGHNIK_01928 1.1e-47 S Bacterial PH domain
FHHGHNIK_01929 9.6e-20 S Pfam:Peptidase_M78
FHHGHNIK_01930 2.2e-20 ps115 K Helix-turn-helix XRE-family like proteins
FHHGHNIK_01931 8.5e-12
FHHGHNIK_01932 1.1e-49
FHHGHNIK_01935 1.4e-78 S Siphovirus Gp157
FHHGHNIK_01936 1.2e-08
FHHGHNIK_01937 3.3e-31
FHHGHNIK_01938 3.7e-219 res L Helicase C-terminal domain protein
FHHGHNIK_01940 6.4e-11
FHHGHNIK_01941 2.2e-20 K Cro/C1-type HTH DNA-binding domain
FHHGHNIK_01942 2.8e-129 L AAA domain
FHHGHNIK_01943 1.2e-90
FHHGHNIK_01944 1e-29
FHHGHNIK_01945 5.7e-125 S Bifunctional DNA primase/polymerase, N-terminal
FHHGHNIK_01946 2.1e-126 S Virulence-associated protein E
FHHGHNIK_01947 2.3e-28 S Virulence-associated protein E
FHHGHNIK_01948 3.6e-52 S VRR-NUC domain
FHHGHNIK_01950 2.5e-07
FHHGHNIK_01951 5.3e-72 arpU S Phage transcriptional regulator, ArpU family
FHHGHNIK_01953 3.6e-29
FHHGHNIK_01954 2.1e-211 ps334 S Terminase-like family
FHHGHNIK_01955 5.7e-264 S Phage portal protein, SPP1 Gp6-like
FHHGHNIK_01956 9.1e-174 S Phage Mu protein F like protein
FHHGHNIK_01958 1.9e-84 S Phage minor structural protein GP20
FHHGHNIK_01959 4.7e-191
FHHGHNIK_01960 4.1e-57
FHHGHNIK_01961 5.7e-56
FHHGHNIK_01962 9.4e-68 S Bacteriophage HK97-gp10, putative tail-component
FHHGHNIK_01963 2.2e-27
FHHGHNIK_01965 8e-242 xkdK S Phage tail sheath C-terminal domain
FHHGHNIK_01966 1.1e-80 xkdM S Phage tail tube protein
FHHGHNIK_01967 3.1e-66 xkdN S Phage XkdN-like tail assembly chaperone protein, TAC
FHHGHNIK_01968 5.8e-279 S phage tail tape measure protein
FHHGHNIK_01969 5.2e-114 ygaU GH23 S protein containing LysM domain
FHHGHNIK_01970 1.3e-188 yqbQ G domain, Protein
FHHGHNIK_01971 3e-54 S Protein of unknown function (DUF2577)
FHHGHNIK_01972 3.6e-68 S lytic transglycosylase activity
FHHGHNIK_01973 4.4e-171 xkdT S Baseplate J-like protein
FHHGHNIK_01974 3.9e-34 S Uncharacterised protein conserved in bacteria (DUF2313)
FHHGHNIK_01975 4.6e-08
FHHGHNIK_01976 1.3e-29
FHHGHNIK_01977 1e-14
FHHGHNIK_01978 1.8e-97 L Reverse transcriptase (RNA-dependent DNA polymerase)
FHHGHNIK_01981 8.1e-27
FHHGHNIK_01983 2.5e-16
FHHGHNIK_01984 5.7e-25
FHHGHNIK_01986 1.7e-60 I alpha/beta hydrolase fold
FHHGHNIK_01987 1.7e-30 I alpha/beta hydrolase fold
FHHGHNIK_01988 1.3e-31
FHHGHNIK_01989 0.0 G Belongs to the glycosyl hydrolase 31 family
FHHGHNIK_01990 5.7e-80 ntd 2.4.2.6 F Nucleoside
FHHGHNIK_01991 1.4e-89 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
FHHGHNIK_01992 8.5e-37 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FHHGHNIK_01993 3.8e-292 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FHHGHNIK_01994 7.2e-135 gmuR K UTRA
FHHGHNIK_01995 8.2e-93 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FHHGHNIK_01996 2.2e-76 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FHHGHNIK_01997 1.5e-185 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FHHGHNIK_01998 1.8e-74 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FHHGHNIK_01999 8.8e-148 ypbG 2.7.1.2 GK ROK family
FHHGHNIK_02000 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
FHHGHNIK_02001 3.3e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FHHGHNIK_02002 8.4e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
FHHGHNIK_02003 1.8e-220 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
FHHGHNIK_02011 9.1e-179
FHHGHNIK_02012 7.1e-44
FHHGHNIK_02013 4.1e-270 ycaM E amino acid
FHHGHNIK_02014 2e-71 S haloacid dehalogenase-like hydrolase
FHHGHNIK_02015 1.4e-18 S haloacid dehalogenase-like hydrolase
FHHGHNIK_02016 2.3e-311 S SH3-like domain
FHHGHNIK_02017 5.8e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FHHGHNIK_02018 7.9e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
FHHGHNIK_02019 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FHHGHNIK_02020 2.9e-185 cggR K Putative sugar-binding domain
FHHGHNIK_02021 4.2e-101
FHHGHNIK_02022 2.8e-282 lsa S ABC transporter
FHHGHNIK_02023 4.6e-304
FHHGHNIK_02024 5.2e-80
FHHGHNIK_02025 4.6e-105 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHHGHNIK_02026 4.7e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
FHHGHNIK_02027 2.9e-204 csaB M Glycosyl transferases group 1
FHHGHNIK_02028 1.8e-281 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FHHGHNIK_02029 1.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
FHHGHNIK_02030 2.6e-223 pbuG S permease
FHHGHNIK_02031 2.3e-35
FHHGHNIK_02032 9.3e-77 atkY K Penicillinase repressor
FHHGHNIK_02033 1.7e-63 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
FHHGHNIK_02034 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
FHHGHNIK_02035 0.0 copA 3.6.3.54 P P-type ATPase
FHHGHNIK_02036 3.9e-100 M Glycosyltransferase, group 1 family protein
FHHGHNIK_02037 2.7e-40 GT2 M transferase activity, transferring glycosyl groups
FHHGHNIK_02038 1.2e-20 epsB M biosynthesis protein
FHHGHNIK_02040 3.4e-07 wbbI M transferase activity, transferring glycosyl groups
FHHGHNIK_02041 2.9e-99 rimL J Acetyltransferase (GNAT) domain
FHHGHNIK_02042 1.6e-53
FHHGHNIK_02043 2.1e-288 S ABC transporter
FHHGHNIK_02044 1.3e-137 thrE S Putative threonine/serine exporter
FHHGHNIK_02045 1.7e-79 S Threonine/Serine exporter, ThrE
FHHGHNIK_02046 2.7e-137 yvpB S Peptidase_C39 like family
FHHGHNIK_02047 5.3e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FHHGHNIK_02048 2.6e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
FHHGHNIK_02049 1.3e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
FHHGHNIK_02050 1.1e-84 S ECF transporter, substrate-specific component
FHHGHNIK_02051 7.3e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
FHHGHNIK_02052 3.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FHHGHNIK_02053 5.3e-59 yabA L Involved in initiation control of chromosome replication
FHHGHNIK_02054 6.3e-154 holB 2.7.7.7 L DNA polymerase III
FHHGHNIK_02055 1.1e-50 yaaQ S Cyclic-di-AMP receptor
FHHGHNIK_02056 8.7e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FHHGHNIK_02057 2.6e-33 S Protein of unknown function (DUF2508)
FHHGHNIK_02058 2.1e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FHHGHNIK_02059 7.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FHHGHNIK_02060 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FHHGHNIK_02061 2e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
FHHGHNIK_02062 2.5e-115 rsmC 2.1.1.172 J Methyltransferase
FHHGHNIK_02063 1.4e-27 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
FHHGHNIK_02064 1.3e-36 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
FHHGHNIK_02065 7e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
FHHGHNIK_02066 6.6e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FHHGHNIK_02067 1.5e-90 yfdV S Membrane transport protein
FHHGHNIK_02068 8.4e-35 yfdV S Membrane transport protein
FHHGHNIK_02069 4.3e-27 yfdV S Membrane transport protein
FHHGHNIK_02070 1.1e-116 phoU P Plays a role in the regulation of phosphate uptake
FHHGHNIK_02071 1.9e-138 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FHHGHNIK_02072 9.3e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FHHGHNIK_02073 2.6e-155 pstA P Phosphate transport system permease protein PstA
FHHGHNIK_02074 1.1e-173 pstC P probably responsible for the translocation of the substrate across the membrane
FHHGHNIK_02075 1.2e-157 pstS P Phosphate
FHHGHNIK_02076 9.4e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
FHHGHNIK_02077 1e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FHHGHNIK_02078 3.1e-101 nusG K Participates in transcription elongation, termination and antitermination
FHHGHNIK_02079 5.9e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
FHHGHNIK_02080 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FHHGHNIK_02081 1.3e-282 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
FHHGHNIK_02082 2.2e-34
FHHGHNIK_02083 8e-94 sigH K Belongs to the sigma-70 factor family
FHHGHNIK_02084 2.3e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHHGHNIK_02085 7.9e-76 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FHHGHNIK_02086 7.3e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
FHHGHNIK_02087 3.3e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FHHGHNIK_02088 4.3e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FHHGHNIK_02089 9.5e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
FHHGHNIK_02090 4.5e-54
FHHGHNIK_02091 3.8e-262 pepC 3.4.22.40 E Peptidase C1-like family
FHHGHNIK_02092 1.1e-142 glcU U sugar transport
FHHGHNIK_02093 5.7e-119
FHHGHNIK_02094 8.1e-169 S Bacteriocin helveticin-J
FHHGHNIK_02095 6.3e-43
FHHGHNIK_02096 1.4e-38 ps115 K Helix-turn-helix XRE-family like proteins
FHHGHNIK_02097 2.4e-48 E Zn peptidase
FHHGHNIK_02098 8.1e-123
FHHGHNIK_02099 7.6e-85 M LysM domain
FHHGHNIK_02101 3.6e-106 K Helix-turn-helix domain
FHHGHNIK_02102 3.2e-115 L Integrase
FHHGHNIK_02103 4e-106
FHHGHNIK_02104 5.6e-212 brpA K Cell envelope-like function transcriptional attenuator common domain protein
FHHGHNIK_02105 0.0 pepF E oligoendopeptidase F
FHHGHNIK_02106 8.6e-10 Z012_06740 S Fic/DOC family
FHHGHNIK_02107 2.6e-49 Z012_06740 S Fic/DOC family
FHHGHNIK_02108 7.1e-18 S Transglycosylase associated protein
FHHGHNIK_02109 1.4e-81 M Glycosyl hydrolases family 25
FHHGHNIK_02110 1.5e-16 M Glycosyl hydrolases family 25
FHHGHNIK_02111 5.1e-25 M Glycosyl hydrolases family 25
FHHGHNIK_02112 2.6e-53
FHHGHNIK_02113 1.5e-109 XK27_00160 S Domain of unknown function (DUF5052)
FHHGHNIK_02114 7.8e-85 adk 2.7.4.3 F topology modulation protein
FHHGHNIK_02115 5.3e-67
FHHGHNIK_02116 3.1e-78 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
FHHGHNIK_02117 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
FHHGHNIK_02118 1.9e-113 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
FHHGHNIK_02119 4.7e-103 S haloacid dehalogenase-like hydrolase
FHHGHNIK_02120 8.6e-44
FHHGHNIK_02122 1.1e-28 S HicB family
FHHGHNIK_02123 8.3e-32 S Biotin synthase
FHHGHNIK_02124 7.5e-76 I Alpha/beta hydrolase family
FHHGHNIK_02125 2.4e-59 S Membrane
FHHGHNIK_02126 6.9e-22 proW P ABC transporter, permease protein
FHHGHNIK_02127 5.3e-245 G Bacterial extracellular solute-binding protein
FHHGHNIK_02128 3.8e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FHHGHNIK_02129 3.9e-170 coaA 2.7.1.33 F Pantothenic acid kinase
FHHGHNIK_02130 1.1e-103 E GDSL-like Lipase/Acylhydrolase
FHHGHNIK_02133 3.2e-55
FHHGHNIK_02134 4.7e-07
FHHGHNIK_02136 1.8e-29 S Bacteriophage abortive infection AbiH
FHHGHNIK_02137 1e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
FHHGHNIK_02138 9.8e-43 yvdE K helix_turn _helix lactose operon repressor
FHHGHNIK_02139 1.8e-104 yvdE K helix_turn _helix lactose operon repressor
FHHGHNIK_02140 3.1e-24 ackA 2.7.2.1 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FHHGHNIK_02141 1.2e-110 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FHHGHNIK_02142 6.5e-90
FHHGHNIK_02144 2.6e-08 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
FHHGHNIK_02145 8.4e-33 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
FHHGHNIK_02146 5.2e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
FHHGHNIK_02147 2.7e-208 yjeM E Amino Acid

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)