ORF_ID e_value Gene_name EC_number CAZy COGs Description
AFONHELG_00001 1.8e-144 2.4.2.3 F Phosphorylase superfamily
AFONHELG_00002 6e-140 2.4.2.3 F Phosphorylase superfamily
AFONHELG_00003 8.1e-119 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
AFONHELG_00004 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AFONHELG_00005 4.7e-11 S Bacterial PH domain
AFONHELG_00006 5.7e-18 S Bacterial PH domain
AFONHELG_00007 4e-27
AFONHELG_00008 1.1e-64 arsC 1.20.4.1 P Belongs to the ArsC family
AFONHELG_00009 2.3e-175 I Carboxylesterase family
AFONHELG_00011 2.3e-170 M Glycosyl hydrolases family 25
AFONHELG_00012 0.0 S Predicted membrane protein (DUF2207)
AFONHELG_00013 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
AFONHELG_00014 6.1e-128 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
AFONHELG_00015 5.3e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
AFONHELG_00016 7.2e-253 S Uncharacterized protein conserved in bacteria (DUF2325)
AFONHELG_00017 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
AFONHELG_00018 1e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AFONHELG_00019 1.7e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
AFONHELG_00020 1.2e-100 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AFONHELG_00021 3.1e-69 yqhY S Asp23 family, cell envelope-related function
AFONHELG_00022 4e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AFONHELG_00023 1.3e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AFONHELG_00024 1.5e-194 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFONHELG_00025 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFONHELG_00026 1.2e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AFONHELG_00027 5.8e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
AFONHELG_00028 1.8e-306 recN L May be involved in recombinational repair of damaged DNA
AFONHELG_00029 3.8e-78 6.3.3.2 S ASCH
AFONHELG_00030 8.9e-110 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
AFONHELG_00031 9.4e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AFONHELG_00032 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AFONHELG_00033 2.8e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AFONHELG_00034 2.3e-243 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AFONHELG_00035 8.6e-145 stp 3.1.3.16 T phosphatase
AFONHELG_00036 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
AFONHELG_00037 1.8e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AFONHELG_00038 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AFONHELG_00039 1.4e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
AFONHELG_00040 8.8e-50
AFONHELG_00041 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AFONHELG_00042 6.8e-57 asp S Asp23 family, cell envelope-related function
AFONHELG_00043 1.4e-303 yloV S DAK2 domain fusion protein YloV
AFONHELG_00044 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AFONHELG_00045 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AFONHELG_00046 4.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AFONHELG_00047 6.8e-195 oppD P Belongs to the ABC transporter superfamily
AFONHELG_00048 3.5e-180 oppF P Belongs to the ABC transporter superfamily
AFONHELG_00049 5.2e-173 oppB P ABC transporter permease
AFONHELG_00050 4.4e-145 oppC P Binding-protein-dependent transport system inner membrane component
AFONHELG_00051 0.0 oppA E ABC transporter substrate-binding protein
AFONHELG_00052 0.0 oppA E ABC transporter substrate-binding protein
AFONHELG_00053 2.2e-96 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AFONHELG_00054 0.0 smc D Required for chromosome condensation and partitioning
AFONHELG_00055 2.4e-165 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AFONHELG_00056 4.7e-287 pipD E Dipeptidase
AFONHELG_00057 1.2e-18
AFONHELG_00058 5.7e-253 yfnA E amino acid
AFONHELG_00059 3.2e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AFONHELG_00060 1.4e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AFONHELG_00061 4.5e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AFONHELG_00062 4.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AFONHELG_00063 8.5e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AFONHELG_00064 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AFONHELG_00065 2.8e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
AFONHELG_00066 1.3e-145 E GDSL-like Lipase/Acylhydrolase family
AFONHELG_00067 9.7e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AFONHELG_00068 2.5e-37 ynzC S UPF0291 protein
AFONHELG_00069 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
AFONHELG_00070 7e-293 mdlA V ABC transporter
AFONHELG_00071 1.2e-295 mdlB V ABC transporter
AFONHELG_00072 0.0 pepO 3.4.24.71 O Peptidase family M13
AFONHELG_00073 3.8e-226 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
AFONHELG_00074 1.9e-112 plsC 2.3.1.51 I Acyltransferase
AFONHELG_00075 2.9e-198 yabB 2.1.1.223 L Methyltransferase small domain
AFONHELG_00076 8.8e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
AFONHELG_00077 2.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AFONHELG_00078 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AFONHELG_00079 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AFONHELG_00080 1e-136 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AFONHELG_00081 1.6e-146 cdsA 2.7.7.41 I Belongs to the CDS family
AFONHELG_00082 8.8e-197 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
AFONHELG_00083 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AFONHELG_00084 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFONHELG_00085 3.2e-83 rimP J Required for maturation of 30S ribosomal subunits
AFONHELG_00086 1.5e-193 nusA K Participates in both transcription termination and antitermination
AFONHELG_00087 3.8e-44 ylxR K Protein of unknown function (DUF448)
AFONHELG_00088 1.2e-46 rplGA J ribosomal protein
AFONHELG_00089 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AFONHELG_00090 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AFONHELG_00091 3.7e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AFONHELG_00092 1e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AFONHELG_00093 1.4e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AFONHELG_00094 6.7e-83 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AFONHELG_00095 0.0 dnaK O Heat shock 70 kDa protein
AFONHELG_00096 3.9e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AFONHELG_00097 8.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
AFONHELG_00098 1.1e-302 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AFONHELG_00099 2.5e-158 hlyX S Transporter associated domain
AFONHELG_00100 1.3e-73
AFONHELG_00101 5.4e-86
AFONHELG_00102 1.9e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
AFONHELG_00103 4.7e-260 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFONHELG_00104 5.3e-80 D Alpha beta
AFONHELG_00105 3.3e-95 L An automated process has identified a potential problem with this gene model
AFONHELG_00106 4.1e-20 D Alpha beta
AFONHELG_00107 1.4e-46
AFONHELG_00108 5.1e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
AFONHELG_00109 4.3e-217 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
AFONHELG_00110 1.6e-213 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
AFONHELG_00111 6.2e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AFONHELG_00112 1.2e-150 yihY S Belongs to the UPF0761 family
AFONHELG_00113 1.7e-164 map 3.4.11.18 E Methionine Aminopeptidase
AFONHELG_00114 1.6e-79 fld C Flavodoxin
AFONHELG_00115 5.2e-57 gtcA S Teichoic acid glycosylation protein
AFONHELG_00116 5.5e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
AFONHELG_00117 1.3e-25
AFONHELG_00119 9.2e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFONHELG_00120 2.7e-206 yfmL 3.6.4.13 L DEAD DEAH box helicase
AFONHELG_00121 2e-129 M Glycosyl hydrolases family 25
AFONHELG_00122 1e-227 potE E amino acid
AFONHELG_00123 7e-101 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AFONHELG_00124 1.3e-238 yhdP S Transporter associated domain
AFONHELG_00125 5e-23 C nitroreductase
AFONHELG_00126 2.5e-18 C nitroreductase
AFONHELG_00128 1.1e-83 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
AFONHELG_00129 1.4e-73
AFONHELG_00130 4.2e-22 glvR K Helix-turn-helix domain, rpiR family
AFONHELG_00131 8e-71 glvR K Helix-turn-helix domain, rpiR family
AFONHELG_00132 7.7e-308 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
AFONHELG_00133 1e-78
AFONHELG_00134 2.3e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AFONHELG_00135 1.7e-206 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AFONHELG_00136 2.3e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AFONHELG_00137 3.1e-50 Z012_06740 S Fic/DOC family
AFONHELG_00138 8.6e-10 Z012_06740 S Fic/DOC family
AFONHELG_00139 1.4e-26 pepF E oligoendopeptidase F
AFONHELG_00140 1.9e-212 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AFONHELG_00141 2.9e-99 rimL J Acetyltransferase (GNAT) domain
AFONHELG_00142 1.6e-53
AFONHELG_00143 2.1e-288 S ABC transporter
AFONHELG_00144 1.3e-137 thrE S Putative threonine/serine exporter
AFONHELG_00145 1.7e-79 S Threonine/Serine exporter, ThrE
AFONHELG_00146 2.7e-137 yvpB S Peptidase_C39 like family
AFONHELG_00147 3.5e-115
AFONHELG_00148 8.4e-54 K HxlR-like helix-turn-helix
AFONHELG_00149 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AFONHELG_00150 0.0 pepO 3.4.24.71 O Peptidase family M13
AFONHELG_00151 1.2e-59 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AFONHELG_00152 4.2e-303 XK27_11280 S Psort location CytoplasmicMembrane, score
AFONHELG_00153 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
AFONHELG_00154 1.5e-141 S response to antibiotic
AFONHELG_00155 3.3e-19
AFONHELG_00156 1.7e-160 arbY M Glycosyl transferase family 8
AFONHELG_00157 4.7e-165 arbZ I Phosphate acyltransferases
AFONHELG_00158 1.2e-106 K Transcriptional regulator, LysR family
AFONHELG_00159 1.3e-51 K LysR substrate binding domain
AFONHELG_00160 1.8e-37 K LysR substrate binding domain
AFONHELG_00161 5e-18 brnQ E Component of the transport system for branched-chain amino acids
AFONHELG_00163 1e-26 K Psort location Cytoplasmic, score
AFONHELG_00165 2.8e-18
AFONHELG_00168 1.3e-69 cpdA S Calcineurin-like phosphoesterase
AFONHELG_00169 6.2e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AFONHELG_00170 3e-69 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AFONHELG_00171 7.2e-106 ypsA S Belongs to the UPF0398 family
AFONHELG_00172 8.3e-26 ybbH_2 K rpiR family
AFONHELG_00173 1.1e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AFONHELG_00174 4.8e-159 yeaE S Aldo/keto reductase family
AFONHELG_00175 2.2e-97 S ECF transporter, substrate-specific component
AFONHELG_00176 0.0 macB_3 V ABC transporter, ATP-binding protein
AFONHELG_00177 1.5e-195 S DUF218 domain
AFONHELG_00178 1.5e-118 S CAAX protease self-immunity
AFONHELG_00179 1.6e-45
AFONHELG_00180 1.7e-154 mutR K Helix-turn-helix XRE-family like proteins
AFONHELG_00181 1.8e-78 S Putative adhesin
AFONHELG_00182 4.2e-281 V ABC transporter transmembrane region
AFONHELG_00183 1.6e-47 S YoeB-like toxin of bacterial type II toxin-antitoxin system
AFONHELG_00184 4.4e-49 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
AFONHELG_00185 1.4e-201 napA P Sodium/hydrogen exchanger family
AFONHELG_00186 0.0 cadA P P-type ATPase
AFONHELG_00187 3e-81 ykuL S (CBS) domain
AFONHELG_00188 2.3e-212 ywhK S Membrane
AFONHELG_00189 3.8e-50
AFONHELG_00190 4.5e-18 S D-Ala-teichoic acid biosynthesis protein
AFONHELG_00191 3.1e-289 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFONHELG_00192 2.9e-240 dltB M MBOAT, membrane-bound O-acyltransferase family
AFONHELG_00193 5.7e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFONHELG_00194 1.1e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AFONHELG_00195 3.9e-173 pbpX2 V Beta-lactamase
AFONHELG_00197 1.2e-10
AFONHELG_00198 7e-69 S CAAX protease self-immunity
AFONHELG_00199 9.6e-16
AFONHELG_00200 6.1e-120 S Protein of unknown function (DUF975)
AFONHELG_00201 3.7e-147 lysA2 M Glycosyl hydrolases family 25
AFONHELG_00202 8.5e-285 ytgP S Polysaccharide biosynthesis protein
AFONHELG_00203 3.3e-36
AFONHELG_00204 1.8e-94 XK27_06780 V ABC transporter permease
AFONHELG_00206 1.3e-69
AFONHELG_00207 2.5e-21 hicB S protein encoded in hypervariable junctions of pilus gene clusters
AFONHELG_00208 2.4e-80 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AFONHELG_00210 1.6e-160 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AFONHELG_00211 5.8e-141 fruR K DeoR C terminal sensor domain
AFONHELG_00212 9e-167 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AFONHELG_00213 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
AFONHELG_00214 2e-172 yjeM E Amino Acid
AFONHELG_00215 5.2e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AFONHELG_00216 8.4e-33 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
AFONHELG_00217 2.6e-08 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
AFONHELG_00219 6.5e-90
AFONHELG_00220 1.6e-134 purD 6.3.4.13 F Belongs to the GARS family
AFONHELG_00221 2.6e-39
AFONHELG_00225 2.9e-48
AFONHELG_00226 2.5e-55 XK27_08635 S UPF0210 protein
AFONHELG_00227 1e-30 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AFONHELG_00228 4.2e-131 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
AFONHELG_00229 1.4e-14 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
AFONHELG_00230 4.4e-94 K acetyltransferase
AFONHELG_00231 5.8e-85 dps P Belongs to the Dps family
AFONHELG_00232 1.8e-215 S SLAP domain
AFONHELG_00234 1.3e-142 mrr L restriction endonuclease
AFONHELG_00235 1.4e-57 L Transposase
AFONHELG_00236 2.4e-72 L Transposase
AFONHELG_00237 2.6e-143 2.4.2.3 F Phosphorylase superfamily
AFONHELG_00238 1.5e-48
AFONHELG_00239 4.8e-63
AFONHELG_00240 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
AFONHELG_00241 1.5e-26
AFONHELG_00242 4e-14
AFONHELG_00243 1.4e-32
AFONHELG_00244 8.3e-27
AFONHELG_00245 5.8e-70
AFONHELG_00246 8e-168 fpaP 3.4.11.5 I Releases the N-terminal proline from various substrates
AFONHELG_00247 5.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
AFONHELG_00248 9.4e-86 uspA T universal stress protein
AFONHELG_00249 5.6e-148 phnD P Phosphonate ABC transporter
AFONHELG_00250 1.3e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AFONHELG_00251 6.5e-129 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
AFONHELG_00252 2.4e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
AFONHELG_00253 1.1e-106 tag 3.2.2.20 L glycosylase
AFONHELG_00254 1.6e-82
AFONHELG_00255 3.5e-271 S Calcineurin-like phosphoesterase
AFONHELG_00256 0.0 asnB 6.3.5.4 E Asparagine synthase
AFONHELG_00257 3.6e-254 yxbA 6.3.1.12 S ATP-grasp enzyme
AFONHELG_00258 2.4e-13 3.6.3.2, 3.6.3.6 P cation transport ATPase
AFONHELG_00259 1.1e-185 3.6.3.6 P Cation transporter/ATPase, N-terminus
AFONHELG_00260 6.3e-73 3.6.3.6 P Cation transporter/ATPase, N-terminus
AFONHELG_00261 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
AFONHELG_00262 9.6e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AFONHELG_00263 3.3e-98 S Iron-sulfur cluster assembly protein
AFONHELG_00264 1.5e-225 XK27_04775 S PAS domain
AFONHELG_00265 7.4e-225 yttB EGP Major facilitator Superfamily
AFONHELG_00266 0.0 pepO 3.4.24.71 O Peptidase family M13
AFONHELG_00267 0.0 kup P Transport of potassium into the cell
AFONHELG_00268 4.5e-71
AFONHELG_00270 5.2e-19
AFONHELG_00271 8.9e-38 S Protein of unknown function (DUF2922)
AFONHELG_00272 2.9e-180 S SLAP domain
AFONHELG_00274 1.8e-30 IQ Enoyl-(Acyl carrier protein) reductase
AFONHELG_00275 6.5e-16
AFONHELG_00276 1.3e-11 S Transglycosylase associated protein
AFONHELG_00277 3e-77 S Asp23 family, cell envelope-related function
AFONHELG_00278 1.2e-22 S Small integral membrane protein (DUF2273)
AFONHELG_00279 1.8e-93
AFONHELG_00280 6.6e-23
AFONHELG_00281 7.1e-36 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AFONHELG_00282 6e-84 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
AFONHELG_00283 2.8e-13 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
AFONHELG_00284 1.4e-108 accA 2.1.3.15, 6.4.1.2 I alpha subunit
AFONHELG_00285 1.3e-86 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AFONHELG_00287 1.1e-31 tdh 1.1.1.14 C Zinc-binding dehydrogenase
AFONHELG_00288 3.3e-95 tdh 1.1.1.14 C Zinc-binding dehydrogenase
AFONHELG_00289 1.1e-16
AFONHELG_00291 3.5e-43 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
AFONHELG_00292 5.2e-108 ubiX 2.5.1.129, 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AFONHELG_00293 1.6e-71 ydeE K AraC family transcriptional regulator
AFONHELG_00294 1.2e-12
AFONHELG_00295 6.1e-71 yeaL S Protein of unknown function (DUF441)
AFONHELG_00296 1.3e-09
AFONHELG_00297 4e-145 cbiQ P cobalt transport
AFONHELG_00298 4e-270 ykoD P ABC transporter, ATP-binding protein
AFONHELG_00299 1.4e-94 L Transposase
AFONHELG_00300 5.7e-64 M Glycosyl transferase family 2
AFONHELG_00301 3.1e-09 cps3F
AFONHELG_00303 8.6e-41 gcvR T Belongs to the UPF0237 family
AFONHELG_00304 9.9e-247 XK27_08635 S UPF0210 protein
AFONHELG_00305 1e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
AFONHELG_00306 7.4e-22
AFONHELG_00307 1.5e-55 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
AFONHELG_00308 4.2e-89 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
AFONHELG_00309 1.6e-65 2.4.1.83 GT2 S GtrA-like protein
AFONHELG_00310 2.8e-171 yfdH GT2 M Glycosyltransferase like family 2
AFONHELG_00311 6.3e-45 S Domain of unknown function (DUF4298)
AFONHELG_00312 5.1e-63 S GIY-YIG catalytic domain
AFONHELG_00313 1.8e-54 3.1.21.3 V Type I restriction modification DNA specificity domain
AFONHELG_00314 2.2e-97 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
AFONHELG_00315 6.2e-78 2.7.7.12 C Domain of unknown function (DUF4931)
AFONHELG_00316 1.5e-120
AFONHELG_00317 8.4e-142 S Belongs to the UPF0246 family
AFONHELG_00318 5.4e-141 aroD S Alpha/beta hydrolase family
AFONHELG_00319 3.6e-111 G phosphoglycerate mutase
AFONHELG_00320 1.6e-94 ygfC K Bacterial regulatory proteins, tetR family
AFONHELG_00321 2e-165 hrtB V ABC transporter permease
AFONHELG_00322 8.8e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
AFONHELG_00323 7.7e-274 pipD E Dipeptidase
AFONHELG_00324 6.8e-37
AFONHELG_00325 9.1e-110 K WHG domain
AFONHELG_00326 2.1e-94 nqr 1.5.1.36 S NADPH-dependent FMN reductase
AFONHELG_00327 5.9e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
AFONHELG_00328 1.6e-148 3.1.3.48 T Tyrosine phosphatase family
AFONHELG_00329 2e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AFONHELG_00330 1.6e-83 cvpA S Colicin V production protein
AFONHELG_00331 8.5e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
AFONHELG_00332 1.5e-147 noc K Belongs to the ParB family
AFONHELG_00333 9.2e-136 soj D Sporulation initiation inhibitor
AFONHELG_00334 1.1e-27 spo0J K Belongs to the ParB family
AFONHELG_00335 3.7e-44 yyzM S Bacterial protein of unknown function (DUF951)
AFONHELG_00336 8e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AFONHELG_00337 4.6e-135 XK27_01040 S Protein of unknown function (DUF1129)
AFONHELG_00338 1.3e-294 V ABC transporter, ATP-binding protein
AFONHELG_00339 0.0 V ABC transporter
AFONHELG_00340 5.1e-122 K response regulator
AFONHELG_00341 2e-208 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
AFONHELG_00342 2e-302 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AFONHELG_00343 1.7e-142 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
AFONHELG_00344 5.7e-213 S Archaea bacterial proteins of unknown function
AFONHELG_00345 2.2e-13 S Enterocin A Immunity
AFONHELG_00346 4.8e-54 S Enterocin A Immunity
AFONHELG_00347 3.3e-62 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
AFONHELG_00348 1.3e-254 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
AFONHELG_00350 1.9e-175 V ABC transporter transmembrane region
AFONHELG_00351 1.7e-42 KLT serine threonine protein kinase
AFONHELG_00352 5.2e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
AFONHELG_00353 2.1e-216 yceI EGP Major facilitator Superfamily
AFONHELG_00354 7.3e-138 S Bacteriocin helveticin-J
AFONHELG_00355 7.2e-176 S SLAP domain
AFONHELG_00356 6e-230 L Transposase
AFONHELG_00357 4.2e-153 glcU U sugar transport
AFONHELG_00358 3.8e-238 K Probable Zinc-ribbon domain
AFONHELG_00359 6.1e-79
AFONHELG_00360 3.5e-11
AFONHELG_00361 2e-26
AFONHELG_00362 1.2e-25 L Transposase
AFONHELG_00363 2.4e-56
AFONHELG_00364 3.6e-45 yvoA_1 K Transcriptional regulator, GntR family
AFONHELG_00365 1.3e-103 skfE V ATPases associated with a variety of cellular activities
AFONHELG_00366 4e-145
AFONHELG_00367 2.5e-118 guaB2 L Resolvase, N terminal domain
AFONHELG_00368 9.6e-302 L Putative transposase DNA-binding domain
AFONHELG_00369 1.3e-45 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
AFONHELG_00370 3.9e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
AFONHELG_00371 1.8e-191 yubA S AI-2E family transporter
AFONHELG_00372 2.7e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AFONHELG_00373 1.6e-67 WQ51_03320 S Protein of unknown function (DUF1149)
AFONHELG_00374 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
AFONHELG_00375 2.8e-224 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
AFONHELG_00376 6.9e-234 S Peptidase M16
AFONHELG_00377 6.8e-133 IQ Enoyl-(Acyl carrier protein) reductase
AFONHELG_00378 1.1e-134 ymfM S Helix-turn-helix domain
AFONHELG_00379 1.9e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFONHELG_00380 4.7e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AFONHELG_00381 4e-218 rny S Endoribonuclease that initiates mRNA decay
AFONHELG_00382 4.2e-209 tagO 2.7.8.33, 2.7.8.35 M transferase
AFONHELG_00383 5.3e-116 yvyE 3.4.13.9 S YigZ family
AFONHELG_00384 9.5e-247 comFA L Helicase C-terminal domain protein
AFONHELG_00385 7.7e-134 comFC S Competence protein
AFONHELG_00386 1.2e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AFONHELG_00387 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AFONHELG_00388 8.6e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AFONHELG_00389 4.4e-24
AFONHELG_00390 4.9e-179 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AFONHELG_00391 2.3e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AFONHELG_00392 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AFONHELG_00393 1.6e-147 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AFONHELG_00394 8.6e-15 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AFONHELG_00395 3.5e-99 S SLAP domain
AFONHELG_00396 1.5e-20 M domain protein
AFONHELG_00397 1.1e-142 glcU U sugar transport
AFONHELG_00398 3.8e-262 pepC 3.4.22.40 E Peptidase C1-like family
AFONHELG_00400 9.7e-09 K transcriptional
AFONHELG_00402 0.0 uvrA2 L ABC transporter
AFONHELG_00403 7.1e-18 S Transglycosylase associated protein
AFONHELG_00404 1.4e-81 M Glycosyl hydrolases family 25
AFONHELG_00405 1.5e-16 M Glycosyl hydrolases family 25
AFONHELG_00406 5.1e-25 M Glycosyl hydrolases family 25
AFONHELG_00407 1.8e-29 M Lysin motif
AFONHELG_00408 7.5e-123 darA C Flavodoxin
AFONHELG_00409 4.8e-141 qmcA O prohibitin homologues
AFONHELG_00410 4.3e-52 L RelB antitoxin
AFONHELG_00411 1.3e-163 ppaC 3.6.1.1 C inorganic pyrophosphatase
AFONHELG_00412 2.2e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AFONHELG_00413 0.0 yeeB L DEAD-like helicases superfamily
AFONHELG_00414 1.2e-80 racA K Domain of unknown function (DUF1836)
AFONHELG_00415 1.2e-152 yitS S EDD domain protein, DegV family
AFONHELG_00417 2.4e-22 dnaX 2.4.99.16, 2.7.7.7 GH13 M domain protein
AFONHELG_00418 2.5e-80 dnaX 2.4.99.16, 2.7.7.7 GH13 M domain protein
AFONHELG_00419 9.2e-136 mdcD 4.1.1.87 I Malonate decarboxylase gamma subunit (MdcE)
AFONHELG_00420 3.4e-115 mdcG 2.7.7.66 H Phosphoribosyl-dephospho-CoA transferase MdcG
AFONHELG_00421 8.5e-137 yisY 1.11.1.10 S Alpha/beta hydrolase family
AFONHELG_00422 8.4e-148 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
AFONHELG_00423 1.7e-41
AFONHELG_00424 4e-136 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AFONHELG_00425 9.7e-124 mgtC S MgtC family
AFONHELG_00426 2.5e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFONHELG_00427 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AFONHELG_00428 9.4e-56 yheA S Belongs to the UPF0342 family
AFONHELG_00429 5.3e-231 yhaO L Ser Thr phosphatase family protein
AFONHELG_00430 0.0 L AAA domain
AFONHELG_00431 4.2e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
AFONHELG_00432 2.3e-50 S PAS domain
AFONHELG_00433 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AFONHELG_00434 8e-28
AFONHELG_00435 1.2e-79 hit FG Scavenger mRNA decapping enzyme C-term binding
AFONHELG_00436 5.5e-42 S Plasmid maintenance system killer
AFONHELG_00437 8.4e-54 higA K Helix-turn-helix XRE-family like proteins
AFONHELG_00438 8.8e-136 ecsA V ABC transporter, ATP-binding protein
AFONHELG_00439 8.9e-215 ecsB U ABC transporter
AFONHELG_00440 2.6e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AFONHELG_00441 1.1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AFONHELG_00442 4.1e-121 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFONHELG_00443 1.7e-259
AFONHELG_00446 6.3e-74 S AAA domain, putative AbiEii toxin, Type IV TA system
AFONHELG_00447 5.5e-30
AFONHELG_00448 1.6e-94
AFONHELG_00449 1.3e-12 S SLAP domain
AFONHELG_00450 1.2e-63 S SLAP domain
AFONHELG_00451 2.3e-221 oxlT P Major Facilitator Superfamily
AFONHELG_00452 2.6e-52 L Helix-turn-helix domain
AFONHELG_00453 1.6e-67 S Hydrolases of the alpha beta superfamily
AFONHELG_00454 2.5e-59 S Hydrolases of the alpha beta superfamily
AFONHELG_00455 6.4e-142 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
AFONHELG_00456 5.6e-115
AFONHELG_00457 2.4e-142 K Helix-turn-helix XRE-family like proteins
AFONHELG_00458 2.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AFONHELG_00460 3e-153 S Sucrose-6F-phosphate phosphohydrolase
AFONHELG_00461 6.6e-72
AFONHELG_00462 2.8e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AFONHELG_00463 2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AFONHELG_00464 4.2e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
AFONHELG_00465 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFONHELG_00466 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFONHELG_00467 2e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AFONHELG_00468 1.7e-34 yaaA S S4 domain protein YaaA
AFONHELG_00469 3.9e-196 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AFONHELG_00470 3.8e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AFONHELG_00471 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
AFONHELG_00472 6e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AFONHELG_00473 2.1e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFONHELG_00474 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AFONHELG_00475 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AFONHELG_00476 6.3e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AFONHELG_00477 6.1e-280 clcA P chloride
AFONHELG_00478 5.7e-208
AFONHELG_00479 1.3e-17
AFONHELG_00480 1.2e-27 mutT F NUDIX domain
AFONHELG_00481 0.0 copA 3.6.3.54 P P-type ATPase
AFONHELG_00482 2.7e-48 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
AFONHELG_00483 1.7e-63 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
AFONHELG_00484 9.3e-77 atkY K Penicillinase repressor
AFONHELG_00485 2.3e-35
AFONHELG_00486 1.3e-222 pbuG S permease
AFONHELG_00487 1.3e-273 pepV 3.5.1.18 E dipeptidase PepV
AFONHELG_00488 1.4e-104 rarA L recombination factor protein RarA
AFONHELG_00489 2.3e-33 rarA L recombination factor protein RarA
AFONHELG_00491 1.2e-58 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
AFONHELG_00492 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
AFONHELG_00493 3.4e-241 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AFONHELG_00495 7.2e-242 amtB P ammonium transporter
AFONHELG_00496 1.2e-20
AFONHELG_00497 7.8e-85 adk 2.7.4.3 F topology modulation protein
AFONHELG_00498 1.5e-109 XK27_00160 S Domain of unknown function (DUF5052)
AFONHELG_00499 3.8e-84 L Integrase
AFONHELG_00500 1e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
AFONHELG_00501 5.4e-41 yvdE K helix_turn _helix lactose operon repressor
AFONHELG_00502 1.5e-29 S MazG-like family
AFONHELG_00503 2.4e-11 L transposase activity
AFONHELG_00504 1.5e-60 S membrane transporter protein
AFONHELG_00505 5e-13 S membrane transporter protein
AFONHELG_00506 6.1e-83 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
AFONHELG_00507 2.7e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
AFONHELG_00508 2.7e-61 S Protein of unknown function (DUF805)
AFONHELG_00509 4.6e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
AFONHELG_00510 1.7e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AFONHELG_00511 2.8e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AFONHELG_00512 2.6e-138 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFONHELG_00513 4e-150 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFONHELG_00514 1.3e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFONHELG_00515 1.1e-60 rplQ J Ribosomal protein L17
AFONHELG_00516 1.5e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFONHELG_00517 5.2e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AFONHELG_00518 2.1e-55 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AFONHELG_00519 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
AFONHELG_00520 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AFONHELG_00521 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AFONHELG_00522 2.2e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AFONHELG_00523 5.9e-71 rplO J Binds to the 23S rRNA
AFONHELG_00524 2.3e-24 rpmD J Ribosomal protein L30
AFONHELG_00525 1.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AFONHELG_00526 2.8e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AFONHELG_00527 4.7e-91 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AFONHELG_00528 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AFONHELG_00529 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFONHELG_00530 3.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AFONHELG_00531 9.8e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AFONHELG_00532 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AFONHELG_00533 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AFONHELG_00534 3.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
AFONHELG_00535 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AFONHELG_00536 1.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AFONHELG_00537 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AFONHELG_00538 1.6e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AFONHELG_00539 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AFONHELG_00540 1.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AFONHELG_00541 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
AFONHELG_00542 9.9e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AFONHELG_00543 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
AFONHELG_00544 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AFONHELG_00545 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AFONHELG_00546 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AFONHELG_00547 2.3e-122 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
AFONHELG_00548 2.7e-91 FbpA K Fibronectin-binding protein
AFONHELG_00549 9.6e-89 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
AFONHELG_00550 4.9e-31 cylA V ATPases associated with a variety of cellular activities
AFONHELG_00551 9.3e-59 tnpR L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
AFONHELG_00552 2.4e-07 M COG0463 Glycosyltransferases involved in cell wall biogenesis
AFONHELG_00553 5.1e-14 S Glycosyltransferase like family 2
AFONHELG_00554 2.2e-160 P CorA-like Mg2+ transporter protein
AFONHELG_00555 4.2e-121 K Crp-like helix-turn-helix domain
AFONHELG_00556 1.3e-176 1.6.5.5 C Zinc-binding dehydrogenase
AFONHELG_00557 3.3e-158 P ABC transporter
AFONHELG_00558 2.1e-188 lysC 2.7.2.4 E Belongs to the aspartokinase family
AFONHELG_00559 0.0 ydgH S MMPL family
AFONHELG_00560 3.3e-98 yobS K Bacterial regulatory proteins, tetR family
AFONHELG_00561 6.8e-157 3.5.2.6 V Beta-lactamase enzyme family
AFONHELG_00562 2.9e-157 corA P CorA-like Mg2+ transporter protein
AFONHELG_00563 4.3e-231 G Bacterial extracellular solute-binding protein
AFONHELG_00564 5.6e-255 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
AFONHELG_00565 4.7e-146 gtsC P Binding-protein-dependent transport system inner membrane component
AFONHELG_00566 3.6e-157 gtsB P ABC-type sugar transport systems, permease components
AFONHELG_00567 5.6e-200 malK P ATPases associated with a variety of cellular activities
AFONHELG_00568 1.9e-280 pipD E Dipeptidase
AFONHELG_00569 1.6e-157 endA F DNA RNA non-specific endonuclease
AFONHELG_00570 7e-162 dnaQ 2.7.7.7 L EXOIII
AFONHELG_00571 5.3e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AFONHELG_00572 1.4e-105 yviA S Protein of unknown function (DUF421)
AFONHELG_00573 2.9e-63 S Protein of unknown function (DUF3290)
AFONHELG_00574 8.4e-139 pnuC H nicotinamide mononucleotide transporter
AFONHELG_00575 7.7e-12
AFONHELG_00576 2.8e-94 S PAS domain
AFONHELG_00577 1.6e-275 V ABC transporter transmembrane region
AFONHELG_00578 2.7e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
AFONHELG_00579 5.1e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AFONHELG_00580 1.3e-95 F Nucleoside 2-deoxyribosyltransferase
AFONHELG_00581 3.3e-67 S Peptidase propeptide and YPEB domain
AFONHELG_00582 1.5e-10 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
AFONHELG_00583 2.2e-109 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AFONHELG_00584 2.5e-74 larC 4.99.1.12 S Protein of unknown function DUF111
AFONHELG_00585 2.6e-34
AFONHELG_00586 3.8e-69 doc S Fic/DOC family
AFONHELG_00587 3.8e-107 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AFONHELG_00588 1.8e-84 S cog cog1373
AFONHELG_00589 9.3e-64 S cog cog1373
AFONHELG_00590 2.8e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AFONHELG_00591 6.8e-95
AFONHELG_00592 4.4e-181 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AFONHELG_00593 1.8e-69 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AFONHELG_00594 5.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
AFONHELG_00596 1.9e-132 cobQ S glutamine amidotransferase
AFONHELG_00597 9.5e-83 M NlpC/P60 family
AFONHELG_00598 4e-154 EG EamA-like transporter family
AFONHELG_00599 2.7e-109
AFONHELG_00600 3.4e-42
AFONHELG_00601 1.1e-31 XK27_05540 S DUF218 domain
AFONHELG_00602 7.5e-85 XK27_05540 S DUF218 domain
AFONHELG_00603 1e-182 yheS_2 S ATPases associated with a variety of cellular activities
AFONHELG_00604 8.6e-84
AFONHELG_00605 6.1e-58
AFONHELG_00606 1.7e-243 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AFONHELG_00607 5.2e-245 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AFONHELG_00608 2.2e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AFONHELG_00611 1e-201 4.2.1.126 S Bacterial protein of unknown function (DUF871)
AFONHELG_00612 3.4e-191 asnA 6.3.1.1 F aspartate--ammonia ligase
AFONHELG_00613 2.6e-153 steT_1 E amino acid
AFONHELG_00614 8.6e-70 steT_1 E amino acid
AFONHELG_00615 2.7e-21 puuD S peptidase C26
AFONHELG_00616 1.2e-244 yifK E Amino acid permease
AFONHELG_00617 3.2e-211 cycA E Amino acid permease
AFONHELG_00618 1.2e-127
AFONHELG_00619 3.9e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AFONHELG_00620 5.8e-158 traA L MobA MobL family protein
AFONHELG_00621 1.6e-63 K Helix-turn-helix XRE-family like proteins
AFONHELG_00622 4.9e-31 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
AFONHELG_00624 2.4e-36
AFONHELG_00625 1.3e-74 S ABC transporter
AFONHELG_00626 1.1e-146 V Beta-lactamase
AFONHELG_00627 2.9e-148 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
AFONHELG_00628 2e-115 dedA S SNARE-like domain protein
AFONHELG_00629 2.2e-84 S Protein of unknown function (DUF1461)
AFONHELG_00630 1.2e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AFONHELG_00631 8.4e-84 yutD S Protein of unknown function (DUF1027)
AFONHELG_00632 1.1e-275 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
AFONHELG_00633 1.1e-55
AFONHELG_00634 6.3e-265 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AFONHELG_00635 1.2e-180 ccpA K catabolite control protein A
AFONHELG_00636 5.4e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
AFONHELG_00637 3e-44
AFONHELG_00638 3.3e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AFONHELG_00639 4.1e-153 ykuT M mechanosensitive ion channel
AFONHELG_00640 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AFONHELG_00641 7e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AFONHELG_00642 8.5e-69 yslB S Protein of unknown function (DUF2507)
AFONHELG_00643 2.2e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AFONHELG_00644 4.6e-54 trxA O Belongs to the thioredoxin family
AFONHELG_00645 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AFONHELG_00646 2.4e-50 yrzB S Belongs to the UPF0473 family
AFONHELG_00647 1e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AFONHELG_00648 2e-42 yrzL S Belongs to the UPF0297 family
AFONHELG_00649 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AFONHELG_00650 4.9e-87
AFONHELG_00651 1.4e-64
AFONHELG_00652 5.2e-235 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AFONHELG_00653 6.7e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
AFONHELG_00654 7.1e-214 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFONHELG_00655 4.9e-284 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AFONHELG_00656 1.1e-37 yajC U Preprotein translocase
AFONHELG_00657 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AFONHELG_00658 3.5e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AFONHELG_00659 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AFONHELG_00660 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AFONHELG_00661 9.7e-289 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AFONHELG_00662 3e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AFONHELG_00663 4.7e-91
AFONHELG_00664 1.4e-45
AFONHELG_00665 5.6e-130 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
AFONHELG_00666 1.1e-145 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
AFONHELG_00667 9.8e-46 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
AFONHELG_00668 2.3e-87 scrB 3.2.1.26 GH32 G invertase
AFONHELG_00669 9.8e-141 scrB 3.2.1.26 GH32 G invertase
AFONHELG_00670 2.5e-178 scrR K Transcriptional regulator, LacI family
AFONHELG_00671 2.5e-122 liaI S membrane
AFONHELG_00672 4.3e-77 XK27_02470 K LytTr DNA-binding domain
AFONHELG_00673 1.7e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AFONHELG_00674 0.0 uup S ABC transporter, ATP-binding protein
AFONHELG_00675 5.3e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AFONHELG_00676 2.6e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
AFONHELG_00677 1.3e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
AFONHELG_00678 1.1e-84 S ECF transporter, substrate-specific component
AFONHELG_00679 7.3e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
AFONHELG_00680 3.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AFONHELG_00681 5.3e-59 yabA L Involved in initiation control of chromosome replication
AFONHELG_00682 6.3e-154 holB 2.7.7.7 L DNA polymerase III
AFONHELG_00683 1.1e-50 yaaQ S Cyclic-di-AMP receptor
AFONHELG_00684 8.7e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AFONHELG_00685 2.6e-33 S Protein of unknown function (DUF2508)
AFONHELG_00686 2.1e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AFONHELG_00687 7.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AFONHELG_00688 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFONHELG_00689 2e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AFONHELG_00690 2.5e-115 rsmC 2.1.1.172 J Methyltransferase
AFONHELG_00691 1.4e-27 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
AFONHELG_00692 1.3e-36 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
AFONHELG_00693 7e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AFONHELG_00694 6.6e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AFONHELG_00695 1.5e-90 yfdV S Membrane transport protein
AFONHELG_00696 8.4e-35 yfdV S Membrane transport protein
AFONHELG_00697 4.3e-27 yfdV S Membrane transport protein
AFONHELG_00698 1.1e-116 phoU P Plays a role in the regulation of phosphate uptake
AFONHELG_00699 1.9e-138 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFONHELG_00700 9.3e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFONHELG_00701 7e-156 pstA P Phosphate transport system permease protein PstA
AFONHELG_00702 1.1e-173 pstC P probably responsible for the translocation of the substrate across the membrane
AFONHELG_00703 1.2e-157 pstS P Phosphate
AFONHELG_00704 9.4e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AFONHELG_00705 1e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AFONHELG_00706 3.1e-101 nusG K Participates in transcription elongation, termination and antitermination
AFONHELG_00707 5.9e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AFONHELG_00708 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AFONHELG_00709 1.3e-282 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
AFONHELG_00710 2.2e-34
AFONHELG_00711 8e-94 sigH K Belongs to the sigma-70 factor family
AFONHELG_00712 2.3e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFONHELG_00713 7.9e-76 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AFONHELG_00714 7.3e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AFONHELG_00715 3.3e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AFONHELG_00716 4.3e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AFONHELG_00717 9.5e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
AFONHELG_00718 4.5e-54
AFONHELG_00719 6.6e-26
AFONHELG_00720 1.7e-27
AFONHELG_00722 3.5e-296 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AFONHELG_00723 8e-196 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AFONHELG_00724 5.5e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AFONHELG_00725 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFONHELG_00726 5.5e-239 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AFONHELG_00727 2.9e-60 yabR J S1 RNA binding domain
AFONHELG_00728 2.6e-59 divIC D Septum formation initiator
AFONHELG_00729 1.8e-34 yabO J S4 domain protein
AFONHELG_00730 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AFONHELG_00731 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AFONHELG_00732 2.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AFONHELG_00733 7.1e-127 S (CBS) domain
AFONHELG_00734 3.6e-89 K transcriptional regulator
AFONHELG_00735 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AFONHELG_00736 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AFONHELG_00737 9.4e-246 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AFONHELG_00738 5.3e-264 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AFONHELG_00739 1.9e-39 rpmE2 J Ribosomal protein L31
AFONHELG_00740 1.3e-33 C coenzyme F420-1:gamma-L-glutamate ligase activity
AFONHELG_00742 1.1e-153 V ABC transporter transmembrane region
AFONHELG_00743 2.7e-85 L HTH-like domain
AFONHELG_00744 2e-106 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AFONHELG_00745 2.8e-34 M Glycosyltransferase like family 2
AFONHELG_00746 1.5e-82 L Reverse transcriptase (RNA-dependent DNA polymerase)
AFONHELG_00747 9.7e-49 S Bacterial toxin of type II toxin-antitoxin system, YafQ
AFONHELG_00750 1.2e-86 metI P ABC transporter permease
AFONHELG_00751 1.6e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AFONHELG_00752 2.8e-162 metQ1 P Belongs to the nlpA lipoprotein family
AFONHELG_00753 0.0 aha1 P E1-E2 ATPase
AFONHELG_00754 7.2e-16 ps301 K sequence-specific DNA binding
AFONHELG_00755 6.8e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AFONHELG_00756 4.5e-185 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AFONHELG_00757 5.5e-37 yifK E Amino acid permease
AFONHELG_00758 1.4e-157 yifK E Amino acid permease
AFONHELG_00759 1.4e-16 yifK E Amino acid permease
AFONHELG_00760 1.2e-61 S PFAM Uncharacterised protein family UPF0150
AFONHELG_00762 6.1e-56 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
AFONHELG_00763 1.9e-54 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
AFONHELG_00764 2.3e-99 3.6.1.27 I Acid phosphatase homologues
AFONHELG_00765 1.9e-131 yitS S Uncharacterised protein, DegV family COG1307
AFONHELG_00766 8.1e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AFONHELG_00767 4.5e-66 S Domain of unknown function (DUF4767)
AFONHELG_00768 1.6e-85 C nitroreductase
AFONHELG_00769 8.8e-148 ypbG 2.7.1.2 GK ROK family
AFONHELG_00770 1.8e-74 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFONHELG_00771 5.9e-100 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFONHELG_00772 6e-63 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFONHELG_00773 2.2e-76 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFONHELG_00774 8.2e-93 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFONHELG_00775 7.2e-135 gmuR K UTRA
AFONHELG_00776 3.8e-292 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFONHELG_00777 3.5e-08 3.6.4.12 L DNA helicase
AFONHELG_00778 1.8e-113 xerS L Belongs to the 'phage' integrase family
AFONHELG_00779 3e-87
AFONHELG_00780 1.6e-21 XK27_04120 S Putative amino acid metabolism
AFONHELG_00781 1.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AFONHELG_00782 4.7e-125 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
AFONHELG_00783 1.1e-102 S Repeat protein
AFONHELG_00784 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AFONHELG_00785 5.6e-18 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
AFONHELG_00786 9.4e-78 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
AFONHELG_00787 2.3e-29 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
AFONHELG_00788 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFONHELG_00789 4.2e-33 ykzG S Belongs to the UPF0356 family
AFONHELG_00790 7.6e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AFONHELG_00791 0.0 typA T GTP-binding protein TypA
AFONHELG_00792 5.4e-204 ftsW D Belongs to the SEDS family
AFONHELG_00793 1.1e-95 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
AFONHELG_00794 8e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AFONHELG_00795 1.9e-192 ylbL T Belongs to the peptidase S16 family
AFONHELG_00796 1.1e-82 comEA L Competence protein ComEA
AFONHELG_00797 0.0 comEC S Competence protein ComEC
AFONHELG_00798 2e-172 holA 2.7.7.7 L DNA polymerase III delta subunit
AFONHELG_00799 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
AFONHELG_00800 7e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AFONHELG_00801 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFONHELG_00802 6e-31 repA S Replication initiator protein A
AFONHELG_00803 2.4e-84 3.4.21.96 S SLAP domain
AFONHELG_00804 2.8e-24 S ABC-2 family transporter protein
AFONHELG_00805 1.2e-103 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AFONHELG_00806 2.9e-72 L COG3547 Transposase and inactivated derivatives
AFONHELG_00807 2.2e-131 K response regulator
AFONHELG_00808 1.7e-292 vicK 2.7.13.3 T Histidine kinase
AFONHELG_00809 1.2e-239 yycH S YycH protein
AFONHELG_00810 7.7e-149 yycI S YycH protein
AFONHELG_00811 7.4e-149 vicX 3.1.26.11 S domain protein
AFONHELG_00812 1.8e-178 htrA 3.4.21.107 O serine protease
AFONHELG_00813 6.1e-91 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AFONHELG_00814 7.4e-102 K Helix-turn-helix XRE-family like proteins
AFONHELG_00815 2.8e-46 S Bacteriocin helveticin-J
AFONHELG_00816 3.7e-76 S SLAP domain
AFONHELG_00817 5.7e-174 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
AFONHELG_00818 9.9e-91 P Cobalt transport protein
AFONHELG_00819 9.8e-236 cbiO1 S ABC transporter, ATP-binding protein
AFONHELG_00820 3.3e-172 K helix_turn_helix, arabinose operon control protein
AFONHELG_00821 1.9e-164 L hmm pf00665
AFONHELG_00822 5.6e-111 L Helix-turn-helix domain
AFONHELG_00823 1.5e-161 htpX O Belongs to the peptidase M48B family
AFONHELG_00824 2.3e-96 lemA S LemA family
AFONHELG_00825 1.4e-190 ybiR P Citrate transporter
AFONHELG_00826 3.9e-69 S Iron-sulphur cluster biosynthesis
AFONHELG_00827 5.8e-32 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
AFONHELG_00828 1.8e-50 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
AFONHELG_00829 3.1e-64 L Transposase DDE domain
AFONHELG_00830 2.4e-22 pstS P T5orf172
AFONHELG_00832 6.9e-19 larA 5.1.2.1 S Domain of unknown function (DUF2088)
AFONHELG_00833 4.9e-72 L Transposase
AFONHELG_00834 1.1e-29 M the current gene model (or a revised gene model) may contain a
AFONHELG_00835 1.4e-28
AFONHELG_00836 8.9e-12
AFONHELG_00837 1.2e-17 S protein conserved in bacteria
AFONHELG_00838 1.3e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
AFONHELG_00839 2e-263 frdC 1.3.5.4 C FAD binding domain
AFONHELG_00840 1.6e-109 M domain protein
AFONHELG_00842 2.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AFONHELG_00843 1.1e-73 fhaB M Rib/alpha-like repeat
AFONHELG_00844 1.4e-45
AFONHELG_00845 5.7e-255 pepC 3.4.22.40 E Peptidase C1-like family
AFONHELG_00846 6.3e-271 P Sodium:sulfate symporter transmembrane region
AFONHELG_00847 4.2e-152 ydjP I Alpha/beta hydrolase family
AFONHELG_00848 4.1e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AFONHELG_00849 9.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
AFONHELG_00850 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
AFONHELG_00851 1e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
AFONHELG_00852 2.2e-138
AFONHELG_00854 6.7e-21 M1-431 S Protein of unknown function (DUF1706)
AFONHELG_00855 6.1e-43 M1-431 S Protein of unknown function (DUF1706)
AFONHELG_00856 5.5e-34 L Resolvase, N terminal domain
AFONHELG_00857 2.7e-32
AFONHELG_00858 1.3e-44
AFONHELG_00864 5.3e-59
AFONHELG_00865 5.5e-33
AFONHELG_00866 1.9e-255 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AFONHELG_00867 8.7e-235 mepA V MATE efflux family protein
AFONHELG_00868 1.5e-230 S Putative peptidoglycan binding domain
AFONHELG_00869 6.9e-93 S ECF-type riboflavin transporter, S component
AFONHELG_00870 8.2e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
AFONHELG_00871 2.9e-204 pbpX1 V Beta-lactamase
AFONHELG_00872 1.8e-104 lacA 2.3.1.79 S Transferase hexapeptide repeat
AFONHELG_00873 5.2e-113 3.6.1.27 I Acid phosphatase homologues
AFONHELG_00874 1.8e-75 C Flavodoxin
AFONHELG_00875 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
AFONHELG_00876 1e-54 ktrB P Potassium uptake protein
AFONHELG_00877 7.9e-246 ynbB 4.4.1.1 P aluminum resistance
AFONHELG_00878 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
AFONHELG_00879 3.6e-271 E Amino acid permease
AFONHELG_00880 1.5e-15 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
AFONHELG_00881 1.8e-27 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
AFONHELG_00882 6.4e-14 V ABC transporter transmembrane region
AFONHELG_00885 1.5e-37 K Helix-turn-helix domain
AFONHELG_00886 4e-57 S Phage derived protein Gp49-like (DUF891)
AFONHELG_00887 6.3e-168 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
AFONHELG_00888 9.2e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AFONHELG_00889 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFONHELG_00890 9e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AFONHELG_00891 6.7e-62 yodB K Transcriptional regulator, HxlR family
AFONHELG_00892 5.7e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFONHELG_00893 6.8e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AFONHELG_00894 3.8e-155 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFONHELG_00895 2.5e-83 S Aminoacyl-tRNA editing domain
AFONHELG_00896 4.3e-278 arlS 2.7.13.3 T Histidine kinase
AFONHELG_00897 7.2e-127 K response regulator
AFONHELG_00898 7.8e-97 yceD S Uncharacterized ACR, COG1399
AFONHELG_00899 3.3e-214 ylbM S Belongs to the UPF0348 family
AFONHELG_00900 4.5e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AFONHELG_00901 2.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
AFONHELG_00902 2.4e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AFONHELG_00903 1.1e-211 yqeH S Ribosome biogenesis GTPase YqeH
AFONHELG_00904 1.1e-92 yqeG S HAD phosphatase, family IIIA
AFONHELG_00905 5.1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AFONHELG_00906 2e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AFONHELG_00907 4.8e-55 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AFONHELG_00908 6.3e-160 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
AFONHELG_00909 8.5e-27 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
AFONHELG_00910 5.4e-25 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AFONHELG_00911 1.9e-27
AFONHELG_00912 4.1e-14 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
AFONHELG_00913 1.8e-95
AFONHELG_00914 9.7e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
AFONHELG_00915 2e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AFONHELG_00916 5.5e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
AFONHELG_00917 1.9e-89 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
AFONHELG_00918 1.4e-98 dnaQ 2.7.7.7 L DNA polymerase III
AFONHELG_00919 7e-164 murB 1.3.1.98 M Cell wall formation
AFONHELG_00920 2.9e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AFONHELG_00921 5.1e-129 potB P ABC transporter permease
AFONHELG_00922 6.5e-124 potC P ABC transporter permease
AFONHELG_00923 1.1e-203 potD P ABC transporter
AFONHELG_00924 1.2e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AFONHELG_00925 8.3e-171 ybbR S YbbR-like protein
AFONHELG_00926 1.5e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AFONHELG_00927 4.4e-149 S hydrolase
AFONHELG_00928 1.9e-88 S Sucrose-6F-phosphate phosphohydrolase
AFONHELG_00929 6.2e-24 S Sucrose-6F-phosphate phosphohydrolase
AFONHELG_00930 1.4e-114
AFONHELG_00931 4.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AFONHELG_00932 7.8e-216 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AFONHELG_00933 1.8e-28 licT K CAT RNA binding domain
AFONHELG_00934 1.2e-88 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFONHELG_00935 2.2e-41 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFONHELG_00936 2.6e-66 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFONHELG_00937 6.2e-22 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFONHELG_00938 1e-184 D Alpha beta
AFONHELG_00939 1.7e-42 larB S AIR carboxylase
AFONHELG_00940 1.6e-32 L COG2963 Transposase and inactivated derivatives
AFONHELG_00941 1.5e-26 KLT serine threonine protein kinase
AFONHELG_00942 6.7e-218 S SLAP domain
AFONHELG_00943 3.9e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFONHELG_00944 2.5e-148 GK ROK family
AFONHELG_00945 5.5e-43
AFONHELG_00946 1.8e-267 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
AFONHELG_00947 1.4e-66 S Domain of unknown function (DUF1934)
AFONHELG_00948 3.9e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AFONHELG_00949 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AFONHELG_00950 2.8e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFONHELG_00951 3.7e-33 S Haloacid dehalogenase-like hydrolase
AFONHELG_00952 4.4e-49 S Haloacid dehalogenase-like hydrolase
AFONHELG_00953 6.3e-284 pipD E Dipeptidase
AFONHELG_00954 9e-158 msmR K AraC-like ligand binding domain
AFONHELG_00955 9.7e-215 pbuX F xanthine permease
AFONHELG_00956 5.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AFONHELG_00957 1.7e-113 K DNA-binding helix-turn-helix protein
AFONHELG_00958 1.1e-20 K Helix-turn-helix
AFONHELG_00959 2.4e-16 K Helix-turn-helix
AFONHELG_00960 1.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AFONHELG_00961 3.2e-29
AFONHELG_00962 3.1e-38
AFONHELG_00963 6e-91 3.6.1.55 L NUDIX domain
AFONHELG_00964 1e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
AFONHELG_00965 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
AFONHELG_00966 2.1e-12 3.6.4.12 S PD-(D/E)XK nuclease family transposase
AFONHELG_00967 2.5e-112 3.6.4.12 S PD-(D/E)XK nuclease family transposase
AFONHELG_00968 8.3e-102 padC Q Phenolic acid decarboxylase
AFONHELG_00969 3.7e-88 padR K Virulence activator alpha C-term
AFONHELG_00970 5.7e-110 M ErfK YbiS YcfS YnhG
AFONHELG_00971 1.1e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AFONHELG_00972 4.2e-242 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AFONHELG_00974 5.5e-39 pspC KT PspC domain
AFONHELG_00975 1.3e-39 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
AFONHELG_00976 4.2e-37 S Enterocin A Immunity
AFONHELG_00977 1.3e-137 yxeH S hydrolase
AFONHELG_00978 2.7e-30 3.6.4.12 S PD-(D/E)XK nuclease family transposase
AFONHELG_00979 1.2e-33 frnE Q DSBA-like thioredoxin domain
AFONHELG_00980 1.1e-36 frnE Q DSBA-like thioredoxin domain
AFONHELG_00981 3.5e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AFONHELG_00982 1.8e-113 M1-798 K Rhodanese Homology Domain
AFONHELG_00983 1.4e-59 CO Thioredoxin
AFONHELG_00984 5.6e-21
AFONHELG_00985 4.7e-13 UW LPXTG-motif cell wall anchor domain protein
AFONHELG_00986 2.4e-19 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
AFONHELG_00987 1.6e-23 infB UW LPXTG-motif cell wall anchor domain protein
AFONHELG_00988 5.3e-69 infB UW LPXTG-motif cell wall anchor domain protein
AFONHELG_00991 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AFONHELG_00992 2.7e-174 prmA J Ribosomal protein L11 methyltransferase
AFONHELG_00993 2.5e-59
AFONHELG_00994 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AFONHELG_00995 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AFONHELG_00996 1.1e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
AFONHELG_00997 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AFONHELG_00998 1e-218 patA 2.6.1.1 E Aminotransferase
AFONHELG_00999 4e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AFONHELG_01000 2.4e-133 S reductase
AFONHELG_01001 3.4e-141 yxeH S hydrolase
AFONHELG_01002 7.8e-16 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFONHELG_01003 4.8e-74 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFONHELG_01004 1.1e-41 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFONHELG_01005 1.1e-240 yfnA E Amino Acid
AFONHELG_01006 7.5e-43 dedA 3.1.3.1 S SNARE associated Golgi protein
AFONHELG_01007 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AFONHELG_01008 7.2e-242 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFONHELG_01009 0.0 oatA I Acyltransferase
AFONHELG_01010 3.9e-173 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AFONHELG_01011 1.1e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AFONHELG_01012 6.2e-33 yrvD S Lipopolysaccharide assembly protein A domain
AFONHELG_01013 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AFONHELG_01014 1.7e-298 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
AFONHELG_01015 1.2e-21 S Protein of unknown function (DUF2929)
AFONHELG_01016 0.0 dnaE 2.7.7.7 L DNA polymerase
AFONHELG_01017 6.6e-184 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AFONHELG_01018 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
AFONHELG_01019 1.4e-167 cvfB S S1 domain
AFONHELG_01020 4e-167 xerD D recombinase XerD
AFONHELG_01021 4.9e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFONHELG_01022 2.5e-101 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AFONHELG_01023 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AFONHELG_01024 5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AFONHELG_01025 4.6e-115 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AFONHELG_01026 9.1e-30 yocH M Lysin motif
AFONHELG_01027 5e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AFONHELG_01028 5.3e-207 rpsA 1.17.7.4 J Ribosomal protein S1
AFONHELG_01029 2.8e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
AFONHELG_01030 8.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AFONHELG_01031 1.9e-228 S Tetratricopeptide repeat protein
AFONHELG_01032 1.4e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFONHELG_01033 8.1e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AFONHELG_01034 9.7e-113 hlyIII S protein, hemolysin III
AFONHELG_01035 7.7e-149 DegV S Uncharacterised protein, DegV family COG1307
AFONHELG_01036 9.3e-36 yozE S Belongs to the UPF0346 family
AFONHELG_01037 9.9e-278 yjcE P Sodium proton antiporter
AFONHELG_01038 7.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AFONHELG_01039 3.7e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFONHELG_01040 2.8e-154 dprA LU DNA protecting protein DprA
AFONHELG_01041 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AFONHELG_01042 1.2e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AFONHELG_01043 1.6e-168 xerC D Phage integrase, N-terminal SAM-like domain
AFONHELG_01044 3e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AFONHELG_01045 5.6e-47 lacX 5.1.3.3 G Aldose 1-epimerase
AFONHELG_01046 3.6e-35
AFONHELG_01048 1.4e-10
AFONHELG_01049 1.3e-109 L transposase, IS605 OrfB family
AFONHELG_01050 4.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AFONHELG_01051 1.3e-151 glnH ET ABC transporter substrate-binding protein
AFONHELG_01052 3e-108 gluC P ABC transporter permease
AFONHELG_01053 1.7e-106 glnP P ABC transporter permease
AFONHELG_01054 5.6e-75 S Protein of unknown function (DUF2974)
AFONHELG_01055 3.3e-63 S Protein of unknown function (DUF2974)
AFONHELG_01056 8.6e-101 S SLAP domain
AFONHELG_01057 1e-235 G Bacterial extracellular solute-binding protein
AFONHELG_01058 7.2e-160 2.7.7.12 C Domain of unknown function (DUF4931)
AFONHELG_01059 1.9e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AFONHELG_01060 1.5e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AFONHELG_01061 0.0 kup P Transport of potassium into the cell
AFONHELG_01062 2e-174 rihB 3.2.2.1 F Nucleoside
AFONHELG_01063 4e-133 gntR K UbiC transcription regulator-associated domain protein
AFONHELG_01064 2.8e-135 S hydrolase
AFONHELG_01065 2e-103 pflC 1.97.1.4 O Radical SAM superfamily
AFONHELG_01066 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
AFONHELG_01067 4.8e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AFONHELG_01068 3.9e-220 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AFONHELG_01069 2.5e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AFONHELG_01070 3.7e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFONHELG_01071 2.6e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFONHELG_01072 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFONHELG_01073 1.2e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AFONHELG_01074 3.8e-201 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
AFONHELG_01075 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
AFONHELG_01076 4.8e-243 purD 6.3.4.13 F Belongs to the GARS family
AFONHELG_01077 9.5e-43 S PAS domain
AFONHELG_01078 3.7e-107 pncA Q Isochorismatase family
AFONHELG_01079 3.2e-267 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AFONHELG_01080 3e-125 3.6.1.13, 3.6.1.55 F NUDIX domain
AFONHELG_01082 2.1e-72 S Iron-sulphur cluster biosynthesis
AFONHELG_01083 8.9e-33 yggT S YGGT family
AFONHELG_01084 1.4e-72 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
AFONHELG_01085 1.6e-204 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AFONHELG_01086 8.8e-235 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AFONHELG_01087 1.1e-129 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AFONHELG_01088 1.4e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AFONHELG_01089 4.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AFONHELG_01090 3e-176 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AFONHELG_01091 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
AFONHELG_01092 5.5e-51 ftsL D Cell division protein FtsL
AFONHELG_01093 1.5e-183 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AFONHELG_01094 9.1e-77 mraZ K Belongs to the MraZ family
AFONHELG_01095 1.4e-53 S Protein of unknown function (DUF3397)
AFONHELG_01096 6.5e-13 S Protein of unknown function (DUF4044)
AFONHELG_01097 3.8e-96 mreD
AFONHELG_01098 2e-144 mreC M Involved in formation and maintenance of cell shape
AFONHELG_01099 4.6e-172 mreB D cell shape determining protein MreB
AFONHELG_01100 2.1e-114 radC L DNA repair protein
AFONHELG_01101 6.3e-125 S Haloacid dehalogenase-like hydrolase
AFONHELG_01102 5.3e-181 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AFONHELG_01104 4e-26
AFONHELG_01105 4e-116 G Peptidase_C39 like family
AFONHELG_01107 1.3e-66 M NlpC/P60 family
AFONHELG_01108 2.1e-29 M NlpC/P60 family
AFONHELG_01109 2.8e-23 M NlpC/P60 family
AFONHELG_01110 2.8e-28 M NlpC/P60 family
AFONHELG_01112 4.5e-39
AFONHELG_01114 8.6e-29 L Belongs to the 'phage' integrase family
AFONHELG_01115 9.1e-53 S Iron-sulfur cluster assembly protein
AFONHELG_01116 6.3e-141 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
AFONHELG_01117 4.2e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
AFONHELG_01118 5.1e-47
AFONHELG_01119 3.2e-21
AFONHELG_01120 7.8e-206 G Major Facilitator Superfamily
AFONHELG_01121 0.0 3.6.3.8 P P-type ATPase
AFONHELG_01122 1.6e-158 yufQ S Belongs to the binding-protein-dependent transport system permease family
AFONHELG_01123 1.5e-166 yufP S Belongs to the binding-protein-dependent transport system permease family
AFONHELG_01124 3e-247 xylG 3.6.3.17 S ABC transporter
AFONHELG_01125 3.6e-178 tcsA S ABC transporter substrate-binding protein PnrA-like
AFONHELG_01126 3.6e-68 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
AFONHELG_01127 1.7e-232 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
AFONHELG_01128 2.5e-44 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
AFONHELG_01129 1e-48 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
AFONHELG_01130 4.7e-40 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
AFONHELG_01131 1.2e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
AFONHELG_01132 1.4e-55 S SNARE associated Golgi protein
AFONHELG_01133 4.1e-41 S SNARE associated Golgi protein
AFONHELG_01134 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
AFONHELG_01135 5.2e-167 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFONHELG_01136 3.9e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AFONHELG_01137 2.1e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
AFONHELG_01138 4.3e-112 yjbK S CYTH
AFONHELG_01139 7.3e-112 yjbH Q Thioredoxin
AFONHELG_01140 1.2e-157 coiA 3.6.4.12 S Competence protein
AFONHELG_01141 1.8e-133 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AFONHELG_01142 2.3e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AFONHELG_01143 4.2e-306 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AFONHELG_01144 8.5e-41 ptsH G phosphocarrier protein HPR
AFONHELG_01145 3.3e-26
AFONHELG_01146 0.0 clpE O Belongs to the ClpA ClpB family
AFONHELG_01147 6.4e-75 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
AFONHELG_01148 1.1e-46
AFONHELG_01149 1.5e-47 glcU U sugar transport
AFONHELG_01150 2.8e-27 glcU U sugar transport
AFONHELG_01151 2.7e-34 glcU U sugar transport
AFONHELG_01152 6.9e-39
AFONHELG_01157 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
AFONHELG_01158 1.6e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AFONHELG_01159 8.9e-237 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AFONHELG_01160 2.6e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AFONHELG_01161 4.6e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AFONHELG_01162 4.2e-164 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AFONHELG_01163 4.4e-121 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AFONHELG_01164 2.8e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AFONHELG_01165 1.6e-31 S RelB antitoxin
AFONHELG_01166 3e-60 GM NmrA-like family
AFONHELG_01167 2.5e-91 clcA P chloride
AFONHELG_01168 1.3e-12 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
AFONHELG_01169 1.9e-30 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
AFONHELG_01170 1e-58 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
AFONHELG_01171 2.7e-17
AFONHELG_01172 3.5e-62
AFONHELG_01173 2.1e-14 S Peptidase propeptide and YPEB domain
AFONHELG_01175 5.9e-120 yfbR S HD containing hydrolase-like enzyme
AFONHELG_01176 1.2e-157 L HNH nucleases
AFONHELG_01177 3.6e-137 glnQ E ABC transporter, ATP-binding protein
AFONHELG_01178 3.5e-291 glnP P ABC transporter permease
AFONHELG_01179 3e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
AFONHELG_01180 4.1e-62 yeaO S Protein of unknown function, DUF488
AFONHELG_01181 9e-123 terC P Integral membrane protein TerC family
AFONHELG_01182 1.3e-90 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
AFONHELG_01183 1.5e-129 cobB K SIR2 family
AFONHELG_01184 6.6e-84
AFONHELG_01185 1.4e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFONHELG_01186 9.8e-177 S Alpha/beta hydrolase of unknown function (DUF915)
AFONHELG_01187 2.1e-145 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFONHELG_01188 1.6e-137 ypuA S Protein of unknown function (DUF1002)
AFONHELG_01189 4e-158 epsV 2.7.8.12 S glycosyl transferase family 2
AFONHELG_01190 1.8e-124 S Alpha/beta hydrolase family
AFONHELG_01191 3.3e-115 GM NmrA-like family
AFONHELG_01192 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AFONHELG_01193 1.1e-67 rplI J Binds to the 23S rRNA
AFONHELG_01194 2.5e-253 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AFONHELG_01195 2.8e-163 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
AFONHELG_01196 7.8e-174 degV S DegV family
AFONHELG_01197 3.9e-44 scrK 2.7.1.2, 2.7.1.4 GK ROK family
AFONHELG_01198 8.7e-125 S ECF-type riboflavin transporter, S component
AFONHELG_01199 0.0 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
AFONHELG_01200 1.9e-153 P ABC-type cobalt transport system permease component CbiQ and related transporters
AFONHELG_01202 2.4e-310 S Domain of unknown function (DUF4430)
AFONHELG_01203 7.9e-183 U FFAT motif binding
AFONHELG_01204 1.2e-79 S Domain of unknown function (DUF4430)
AFONHELG_01205 1.4e-30 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
AFONHELG_01206 2.4e-48 E Zn peptidase
AFONHELG_01207 1.4e-38 ps115 K Helix-turn-helix XRE-family like proteins
AFONHELG_01208 6.3e-43
AFONHELG_01209 2.8e-169 S Bacteriocin helveticin-J
AFONHELG_01210 1.3e-79
AFONHELG_01212 1.2e-16
AFONHELG_01213 4.7e-40 ropB K Transcriptional regulator
AFONHELG_01215 2.4e-100
AFONHELG_01216 4.3e-20 K Helix-turn-helix XRE-family like proteins
AFONHELG_01218 3.9e-59 speG J Acetyltransferase (GNAT) domain
AFONHELG_01220 4.6e-61 L Transposase DDE domain
AFONHELG_01221 2.2e-67 L Transposase DDE domain
AFONHELG_01227 6.6e-41 repA S Replication initiator protein A
AFONHELG_01228 4.6e-205 yjeM E Amino Acid
AFONHELG_01229 5.6e-59 yjeM E Amino Acid
AFONHELG_01230 9.2e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AFONHELG_01231 5.2e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
AFONHELG_01232 2.7e-249 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AFONHELG_01233 6.1e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AFONHELG_01234 5.8e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AFONHELG_01235 7.3e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AFONHELG_01236 1.3e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AFONHELG_01237 6.5e-210 aspC 2.6.1.1 E Aminotransferase
AFONHELG_01238 2e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AFONHELG_01239 6.5e-204 pbpX1 V Beta-lactamase
AFONHELG_01240 9.7e-112 3.6.1.55 F NUDIX domain
AFONHELG_01241 2.9e-293 I Protein of unknown function (DUF2974)
AFONHELG_01242 4.6e-245 thrC 4.2.3.1 E Threonine synthase
AFONHELG_01243 7.5e-120 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
AFONHELG_01244 2.4e-40 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
AFONHELG_01245 2.3e-110 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AFONHELG_01246 3.5e-104
AFONHELG_01247 9.6e-158 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFONHELG_01248 1.9e-206 L Belongs to the 'phage' integrase family
AFONHELG_01249 1.1e-47 S Bacterial PH domain
AFONHELG_01250 9.6e-20 S Pfam:Peptidase_M78
AFONHELG_01251 2.2e-20 ps115 K Helix-turn-helix XRE-family like proteins
AFONHELG_01252 8.5e-12
AFONHELG_01253 1.1e-49
AFONHELG_01256 5.3e-78 S Siphovirus Gp157
AFONHELG_01257 1.2e-08
AFONHELG_01258 3.3e-31
AFONHELG_01259 1.6e-222 res L Helicase C-terminal domain protein
AFONHELG_01261 6.4e-11
AFONHELG_01262 2.2e-20 K Cro/C1-type HTH DNA-binding domain
AFONHELG_01263 1.2e-90
AFONHELG_01264 1e-29
AFONHELG_01265 5.7e-125 S Bifunctional DNA primase/polymerase, N-terminal
AFONHELG_01266 2.2e-182 S Virulence-associated protein E
AFONHELG_01267 7.2e-53 S VRR-NUC domain
AFONHELG_01269 3e-08
AFONHELG_01271 1.6e-71 arpU S Phage transcriptional regulator, ArpU family
AFONHELG_01272 8.6e-47
AFONHELG_01273 1.4e-234 ps334 S Terminase-like family
AFONHELG_01274 7.2e-259 S Phage portal protein, SPP1 Gp6-like
AFONHELG_01275 1.6e-178 S Phage Mu protein F like protein
AFONHELG_01277 8.7e-85 S Phage minor structural protein GP20
AFONHELG_01278 1.6e-191
AFONHELG_01279 2e-56
AFONHELG_01280 2e-56
AFONHELG_01281 4.7e-67 S Bacteriophage HK97-gp10, putative tail-component
AFONHELG_01282 1.5e-26
AFONHELG_01284 1.4e-241 xkdK S Phage tail sheath C-terminal domain
AFONHELG_01285 1.1e-80 xkdM S Phage tail tube protein
AFONHELG_01286 3.1e-66 xkdN S Phage XkdN-like tail assembly chaperone protein, TAC
AFONHELG_01287 1.5e-271 S phage tail tape measure protein
AFONHELG_01288 1.8e-114 ygaU GH23 S protein containing LysM domain
AFONHELG_01289 3.3e-184 yqbQ G domain, Protein
AFONHELG_01290 2.8e-52 S Protein of unknown function (DUF2577)
AFONHELG_01291 1.5e-66 S Protein of unknown function (DUF2634)
AFONHELG_01292 4.4e-171 xkdT S Baseplate J-like protein
AFONHELG_01293 1e-34 S Uncharacterised protein conserved in bacteria (DUF2313)
AFONHELG_01294 4.6e-08
AFONHELG_01295 2e-30
AFONHELG_01298 8.1e-27
AFONHELG_01300 2.5e-16
AFONHELG_01301 5.7e-25
AFONHELG_01302 6.9e-177 M Glycosyl hydrolases family 25
AFONHELG_01304 6.3e-85 XK27_08435 K UTRA
AFONHELG_01305 8.1e-64 L Resolvase, N terminal domain
AFONHELG_01306 1.2e-249 L TIGRFAM transposase, IS605 OrfB family
AFONHELG_01307 1.3e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AFONHELG_01308 1.1e-96 rpiR1 K Helix-turn-helix domain, rpiR family
AFONHELG_01309 1.4e-47 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AFONHELG_01310 1.6e-43 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AFONHELG_01311 3.6e-141 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
AFONHELG_01312 6.5e-18 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
AFONHELG_01313 7.7e-32 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
AFONHELG_01314 1.1e-41 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
AFONHELG_01315 2.4e-215 naiP EGP Major facilitator Superfamily
AFONHELG_01316 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
AFONHELG_01317 8.8e-09 oppA E ABC transporter
AFONHELG_01318 1.1e-43 oppA E ABC transporter
AFONHELG_01319 2e-214 Q Imidazolonepropionase and related amidohydrolases
AFONHELG_01320 9e-58 psiE S Phosphate-starvation-inducible E
AFONHELG_01321 2.2e-32 S Biotin synthase
AFONHELG_01322 2.9e-62 4.2.99.20 S Alpha/beta hydrolase family
AFONHELG_01323 9.3e-25 I carboxylic ester hydrolase activity
AFONHELG_01324 1.2e-87 S Membrane
AFONHELG_01325 5.2e-49 S Membrane
AFONHELG_01326 1.9e-123 C Zinc-binding dehydrogenase
AFONHELG_01327 4.1e-143 proX M ABC transporter, substrate-binding protein, QAT family
AFONHELG_01328 7e-89 proWZ P ABC transporter permease
AFONHELG_01329 3.8e-110 proV E ABC transporter, ATP-binding protein
AFONHELG_01330 8.5e-87 proW P ABC transporter, permease protein
AFONHELG_01331 6.9e-07 S ParE toxin of type II toxin-antitoxin system, parDE
AFONHELG_01332 2.2e-63 mta K helix_turn_helix, mercury resistance
AFONHELG_01333 8.6e-38 mta K helix_turn_helix, mercury resistance
AFONHELG_01334 6.8e-95 yyaR K Acetyltransferase (GNAT) domain
AFONHELG_01335 0.0 uvrA3 L excinuclease ABC, A subunit
AFONHELG_01338 4.9e-51 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
AFONHELG_01339 1.2e-18 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
AFONHELG_01340 6.6e-75 K LytTr DNA-binding domain
AFONHELG_01341 1.9e-74 S Protein of unknown function (DUF3021)
AFONHELG_01342 2.9e-60 L COG2963 Transposase and inactivated derivatives
AFONHELG_01343 2.5e-155 L COG2963 Transposase and inactivated derivatives
AFONHELG_01344 5.9e-188 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AFONHELG_01345 4.9e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
AFONHELG_01346 4.1e-144 accA 2.1.3.15, 6.4.1.2 I alpha subunit
AFONHELG_01347 6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AFONHELG_01348 4.7e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
AFONHELG_01349 3.8e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
AFONHELG_01350 1.4e-78 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AFONHELG_01351 1.5e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AFONHELG_01352 1.9e-127 IQ reductase
AFONHELG_01353 1.7e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
AFONHELG_01354 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AFONHELG_01355 9.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFONHELG_01356 2.1e-79 marR K Transcriptional regulator
AFONHELG_01357 3.8e-78 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AFONHELG_01358 4.3e-31 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
AFONHELG_01359 2.2e-144 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
AFONHELG_01360 1.8e-13 ytgB S Transglycosylase associated protein
AFONHELG_01361 8.8e-54 L COG2963 Transposase and inactivated derivatives
AFONHELG_01362 5.5e-149
AFONHELG_01363 1.5e-161
AFONHELG_01364 4.8e-133
AFONHELG_01365 7.5e-263 glnA 6.3.1.2 E glutamine synthetase
AFONHELG_01366 1.3e-131 ynbB 4.4.1.1 P aluminum resistance
AFONHELG_01367 9.7e-25 ynbB 4.4.1.1 P aluminum resistance
AFONHELG_01368 1.3e-168 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AFONHELG_01369 5e-69 yqhL P Rhodanese-like protein
AFONHELG_01370 1.2e-32 yqgQ S Bacterial protein of unknown function (DUF910)
AFONHELG_01371 3.5e-115 gluP 3.4.21.105 S Rhomboid family
AFONHELG_01372 1.6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AFONHELG_01373 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AFONHELG_01374 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
AFONHELG_01375 0.0 S membrane
AFONHELG_01376 4.4e-169 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
AFONHELG_01377 2.5e-107 S Peptidase family M23
AFONHELG_01378 3.7e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
AFONHELG_01379 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AFONHELG_01380 9.4e-69 yqeY S YqeY-like protein
AFONHELG_01381 8e-174 phoH T phosphate starvation-inducible protein PhoH
AFONHELG_01382 8.5e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AFONHELG_01383 2.8e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AFONHELG_01384 1e-131 recO L Involved in DNA repair and RecF pathway recombination
AFONHELG_01385 6.1e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AFONHELG_01386 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AFONHELG_01387 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AFONHELG_01388 1e-196 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AFONHELG_01389 2.2e-122 S Peptidase family M23
AFONHELG_01390 3.6e-68 mutT 3.6.1.55 F NUDIX domain
AFONHELG_01391 3.2e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
AFONHELG_01392 1e-18 S Membrane
AFONHELG_01394 5e-18
AFONHELG_01395 1.1e-31 sip L Belongs to the 'phage' integrase family
AFONHELG_01396 3.4e-44 S Phage integrase family
AFONHELG_01398 5.7e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AFONHELG_01399 1e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
AFONHELG_01400 1.9e-81 comGF U Putative Competence protein ComGF
AFONHELG_01401 3.9e-41
AFONHELG_01402 6.1e-73
AFONHELG_01403 1.1e-43 comGC U competence protein ComGC
AFONHELG_01404 8.4e-174 comGB NU type II secretion system
AFONHELG_01405 2.5e-175 comGA NU Type II IV secretion system protein
AFONHELG_01406 2.6e-132 yebC K Transcriptional regulatory protein
AFONHELG_01407 3.2e-84 S VanZ like family
AFONHELG_01408 1.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFONHELG_01409 1.1e-295 E Amino acid permease
AFONHELG_01410 8.5e-60 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
AFONHELG_01411 1.2e-144 mmuP E amino acid
AFONHELG_01412 3.6e-75 mmuP E amino acid
AFONHELG_01413 3e-237 N Uncharacterized conserved protein (DUF2075)
AFONHELG_01414 8e-12 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
AFONHELG_01415 2.4e-13 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
AFONHELG_01416 6e-22 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
AFONHELG_01417 3.2e-100 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
AFONHELG_01418 1.8e-13
AFONHELG_01419 5.3e-64
AFONHELG_01420 1.9e-24
AFONHELG_01421 1.9e-23
AFONHELG_01422 1.4e-257 S C4-dicarboxylate anaerobic carrier
AFONHELG_01423 3.6e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AFONHELG_01425 1.1e-15
AFONHELG_01426 8e-102 S LexA-binding, inner membrane-associated putative hydrolase
AFONHELG_01427 2.5e-36
AFONHELG_01428 1.2e-155 malY 4.4.1.8 E Aminotransferase, class I
AFONHELG_01429 5.4e-47
AFONHELG_01430 4.2e-240 brnQ U Component of the transport system for branched-chain amino acids
AFONHELG_01431 2.7e-56 S Protein of unknown function (DUF554)
AFONHELG_01432 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AFONHELG_01433 1.2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AFONHELG_01434 5e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AFONHELG_01435 9.2e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AFONHELG_01436 2.2e-246 dnaB L Replication initiation and membrane attachment
AFONHELG_01437 9.9e-166 dnaI L Primosomal protein DnaI
AFONHELG_01438 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AFONHELG_01439 3.7e-88
AFONHELG_01440 1.1e-95
AFONHELG_01441 8.8e-09 S ACT domain
AFONHELG_01442 1.2e-182 S Domain of unknown function (DUF389)
AFONHELG_01443 1.6e-128 M Glycosyl transferase family 2
AFONHELG_01444 2.3e-117 M Glycosyltransferase sugar-binding region containing DXD motif
AFONHELG_01445 1.5e-78 pssE S Glycosyltransferase family 28 C-terminal domain
AFONHELG_01446 5.2e-83 cpsF M Oligosaccharide biosynthesis protein Alg14 like
AFONHELG_01447 1.4e-121 rfbP M Bacterial sugar transferase
AFONHELG_01448 2.8e-145 ywqE 3.1.3.48 GM PHP domain protein
AFONHELG_01449 6.9e-115 ywqD 2.7.10.1 D Capsular exopolysaccharide family
AFONHELG_01450 9.2e-124 epsB M biosynthesis protein
AFONHELG_01451 1.9e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AFONHELG_01452 2.5e-199 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AFONHELG_01453 3.5e-137 M NlpC/P60 family
AFONHELG_01454 1.9e-125 M NlpC P60 family protein
AFONHELG_01455 3.4e-95 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AFONHELG_01456 6.2e-117 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
AFONHELG_01457 3.1e-101 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
AFONHELG_01458 4.9e-110 G Phosphoglycerate mutase family
AFONHELG_01459 4.1e-195 D nuclear chromosome segregation
AFONHELG_01460 4.4e-57 M LysM domain protein
AFONHELG_01461 4.7e-160 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AFONHELG_01462 2.1e-107 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFONHELG_01463 1.3e-94 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFONHELG_01464 9.6e-13
AFONHELG_01465 1.6e-260 S Archaea bacterial proteins of unknown function
AFONHELG_01466 2.9e-170 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
AFONHELG_01467 3e-63
AFONHELG_01468 5.6e-12
AFONHELG_01469 1e-69 S Iron-sulphur cluster biosynthesis
AFONHELG_01470 3.2e-29 S protein conserved in bacteria
AFONHELG_01471 3.2e-19 S protein conserved in bacteria
AFONHELG_01472 1e-31 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
AFONHELG_01473 5.3e-192 pbpX1 V Beta-lactamase
AFONHELG_01474 0.0 L Helicase C-terminal domain protein
AFONHELG_01475 9e-262 E amino acid
AFONHELG_01476 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
AFONHELG_01477 2e-168 yniA G Phosphotransferase enzyme family
AFONHELG_01478 1.3e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFONHELG_01479 8.6e-133 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
AFONHELG_01480 2.5e-178 ABC-SBP S ABC transporter
AFONHELG_01481 1.1e-124 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
AFONHELG_01482 1.1e-136 XK27_08845 S ABC transporter, ATP-binding protein
AFONHELG_01483 5.9e-40
AFONHELG_01484 1.3e-11
AFONHELG_01485 6.8e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
AFONHELG_01486 1.6e-175 K AI-2E family transporter
AFONHELG_01487 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
AFONHELG_01488 1.1e-07 S Domain of unknown function (DUF4430)
AFONHELG_01489 1.4e-84 S ECF transporter, substrate-specific component
AFONHELG_01490 6e-97 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
AFONHELG_01491 8e-148 S Putative ABC-transporter type IV
AFONHELG_01492 1.1e-229 S LPXTG cell wall anchor motif
AFONHELG_01493 4.1e-251 pipD E Dipeptidase
AFONHELG_01494 1.5e-247 V Restriction endonuclease
AFONHELG_01495 9.4e-89 K Bacterial regulatory proteins, tetR family
AFONHELG_01496 1.1e-57 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AFONHELG_01497 4.3e-130 ybbM S Uncharacterised protein family (UPF0014)
AFONHELG_01498 2.9e-111 ybbL S ABC transporter, ATP-binding protein
AFONHELG_01499 1.3e-27 WQ51_00220 K Helix-turn-helix XRE-family like proteins
AFONHELG_01502 1.7e-109 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
AFONHELG_01503 5.5e-15
AFONHELG_01504 0.0 L Type III restriction enzyme, res subunit
AFONHELG_01506 1.7e-120 yhiD S MgtC family
AFONHELG_01507 8.2e-240 I Protein of unknown function (DUF2974)
AFONHELG_01508 8.1e-36
AFONHELG_01510 8.8e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AFONHELG_01511 2.2e-168 whiA K May be required for sporulation
AFONHELG_01512 1.3e-193 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AFONHELG_01513 6.9e-164 rapZ S Displays ATPase and GTPase activities
AFONHELG_01514 3.1e-82 S Short repeat of unknown function (DUF308)
AFONHELG_01515 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AFONHELG_01516 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AFONHELG_01517 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
AFONHELG_01518 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
AFONHELG_01519 2.6e-166 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
AFONHELG_01520 7.5e-180 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
AFONHELG_01521 1.2e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
AFONHELG_01522 4.1e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AFONHELG_01523 1.1e-259 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
AFONHELG_01524 8.2e-174
AFONHELG_01525 6.7e-130
AFONHELG_01526 6.8e-30
AFONHELG_01527 1.6e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFONHELG_01528 8.2e-120 luxT K Bacterial regulatory proteins, tetR family
AFONHELG_01529 2.2e-127
AFONHELG_01530 1.3e-260 glnPH2 P ABC transporter permease
AFONHELG_01531 5.8e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AFONHELG_01532 4.3e-228 S Cysteine-rich secretory protein family
AFONHELG_01533 2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AFONHELG_01534 7.2e-90
AFONHELG_01535 7e-201 yibE S overlaps another CDS with the same product name
AFONHELG_01536 2.9e-129 yibF S overlaps another CDS with the same product name
AFONHELG_01546 4.8e-221 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
AFONHELG_01547 8.4e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
AFONHELG_01548 3.3e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AFONHELG_01549 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AFONHELG_01550 2.3e-29 secG U Preprotein translocase
AFONHELG_01551 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AFONHELG_01552 1.5e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AFONHELG_01554 1.4e-167 psaA P Belongs to the bacterial solute-binding protein 9 family
AFONHELG_01557 1.6e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AFONHELG_01558 1.2e-258 qacA EGP Major facilitator Superfamily
AFONHELG_01559 7e-149 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AFONHELG_01560 3.9e-119 3.6.1.27 I Acid phosphatase homologues
AFONHELG_01561 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AFONHELG_01562 1.4e-295 ytgP S Polysaccharide biosynthesis protein
AFONHELG_01563 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFONHELG_01564 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AFONHELG_01565 2.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
AFONHELG_01567 7.2e-43
AFONHELG_01568 4.4e-123 magIII L Base excision DNA repair protein, HhH-GPD family
AFONHELG_01569 5.8e-26 folT S ECF transporter, substrate-specific component
AFONHELG_01570 6.5e-57 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AFONHELG_01571 8.6e-201 folE 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 F GTP cyclohydrolase 1
AFONHELG_01572 2.1e-79 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AFONHELG_01573 1.4e-198 folP 2.5.1.15 H dihydropteroate synthase
AFONHELG_01574 1.7e-96 3.6.1.55, 3.6.1.67 F NUDIX domain
AFONHELG_01575 2.7e-73 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
AFONHELG_01576 8.6e-57 adhR K helix_turn_helix, mercury resistance
AFONHELG_01577 6e-112 papP P ABC transporter, permease protein
AFONHELG_01578 2.6e-86 P ABC transporter permease
AFONHELG_01579 1.6e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AFONHELG_01580 9.1e-161 cjaA ET ABC transporter substrate-binding protein
AFONHELG_01581 6.9e-245 G Bacterial extracellular solute-binding protein
AFONHELG_01582 3.8e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AFONHELG_01583 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
AFONHELG_01584 1.5e-103 E GDSL-like Lipase/Acylhydrolase
AFONHELG_01585 3.6e-76 yjcF S Acetyltransferase (GNAT) domain
AFONHELG_01586 1.4e-144 aatB ET ABC transporter substrate-binding protein
AFONHELG_01587 1.3e-54 glnQ 3.6.3.21 E ABC transporter
AFONHELG_01588 0.0 helD 3.6.4.12 L DNA helicase
AFONHELG_01589 1.7e-125 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
AFONHELG_01590 2.7e-125 pgm3 G Phosphoglycerate mutase family
AFONHELG_01591 1.2e-19 2.7.7.12 C Domain of unknown function (DUF4931)
AFONHELG_01592 2.1e-179 S Putative peptidoglycan binding domain
AFONHELG_01593 1.5e-23
AFONHELG_01594 2.7e-187 dtpT U amino acid peptide transporter
AFONHELG_01595 1.3e-32 dtpT U amino acid peptide transporter
AFONHELG_01596 0.0 pepN 3.4.11.2 E aminopeptidase
AFONHELG_01598 2.5e-59 lysM M LysM domain
AFONHELG_01599 5.5e-170
AFONHELG_01600 2.5e-212 mdtG EGP Major facilitator Superfamily
AFONHELG_01601 3.5e-106 K LysR substrate binding domain
AFONHELG_01602 2.5e-19
AFONHELG_01603 5.8e-211 S Sterol carrier protein domain
AFONHELG_01604 3.4e-97 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
AFONHELG_01605 5.2e-77 arcC 2.7.2.2 E Belongs to the carbamate kinase family
AFONHELG_01606 6.9e-69 arcC 2.7.2.2 E Belongs to the carbamate kinase family
AFONHELG_01607 5.7e-141 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AFONHELG_01608 1.9e-90 arcA 3.5.3.6 E Arginine
AFONHELG_01609 1.1e-50 arcA 3.5.3.6 E Arginine
AFONHELG_01610 3.2e-26 arcA 3.5.3.6 E Arginine
AFONHELG_01611 1.8e-156 lysR5 K LysR substrate binding domain
AFONHELG_01612 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
AFONHELG_01613 3.8e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AFONHELG_01614 4.6e-216 iscS2 2.8.1.7 E Aminotransferase class V
AFONHELG_01615 3.9e-280 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AFONHELG_01616 8.9e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AFONHELG_01617 6.6e-81 yueI S Protein of unknown function (DUF1694)
AFONHELG_01618 1.4e-240 rarA L recombination factor protein RarA
AFONHELG_01619 2.5e-35
AFONHELG_01620 3.1e-78 usp6 T universal stress protein
AFONHELG_01621 1.9e-217 rodA D Belongs to the SEDS family
AFONHELG_01622 7.3e-33 S Protein of unknown function (DUF2969)
AFONHELG_01623 3.8e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
AFONHELG_01624 1.9e-178 mbl D Cell shape determining protein MreB Mrl
AFONHELG_01625 5.8e-30 ywzB S Protein of unknown function (DUF1146)
AFONHELG_01626 7.7e-55 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AFONHELG_01627 7.6e-237 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AFONHELG_01628 7e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AFONHELG_01629 4.8e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AFONHELG_01630 2.2e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFONHELG_01631 3.2e-44 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AFONHELG_01632 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFONHELG_01633 2.1e-126 atpB C it plays a direct role in the translocation of protons across the membrane
AFONHELG_01634 8.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AFONHELG_01635 1.9e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AFONHELG_01636 1.9e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AFONHELG_01637 6.9e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AFONHELG_01638 2.2e-113 tdk 2.7.1.21 F thymidine kinase
AFONHELG_01639 3.8e-246 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
AFONHELG_01642 1.8e-195 ampC V Beta-lactamase
AFONHELG_01643 2.8e-22 EGP Major facilitator Superfamily
AFONHELG_01644 2.1e-107 EGP Major facilitator Superfamily
AFONHELG_01645 1.2e-34 EGP Major facilitator Superfamily
AFONHELG_01646 6e-260 pgi 5.3.1.9 G Belongs to the GPI family
AFONHELG_01647 1.8e-63 vanZ V VanZ like family
AFONHELG_01648 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AFONHELG_01649 5.3e-270 yclK 2.7.13.3 T Histidine kinase
AFONHELG_01650 5.9e-129 K Transcriptional regulatory protein, C terminal
AFONHELG_01651 5.4e-60 S SdpI/YhfL protein family
AFONHELG_01652 1.9e-167 manA 5.3.1.8 G mannose-6-phosphate isomerase
AFONHELG_01653 6.6e-72 patB 4.4.1.8 E Aminotransferase, class I
AFONHELG_01654 2e-61 patB 4.4.1.8 E Aminotransferase, class I
AFONHELG_01655 1.5e-58 patB 4.4.1.8 E Aminotransferase, class I
AFONHELG_01656 4e-31 M Protein of unknown function (DUF3737)
AFONHELG_01657 1.6e-139 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFONHELG_01658 6.3e-88 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFONHELG_01659 1e-90 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
AFONHELG_01660 1.4e-10 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AFONHELG_01661 1.9e-09 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AFONHELG_01662 9.9e-112 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AFONHELG_01663 4.1e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AFONHELG_01664 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
AFONHELG_01665 3.8e-117 srtA 3.4.22.70 M sortase family
AFONHELG_01666 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AFONHELG_01667 9.8e-51 K DNA-templated transcription, initiation
AFONHELG_01668 2.3e-100
AFONHELG_01669 2e-222 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AFONHELG_01670 3.7e-207 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
AFONHELG_01671 0.0 yjbQ P TrkA C-terminal domain protein
AFONHELG_01672 1.7e-118 gepA K Protein of unknown function (DUF4065)
AFONHELG_01673 3.3e-09 ps301 K Protein of unknown function (DUF4065)
AFONHELG_01674 1.2e-177 S Oxidoreductase family, NAD-binding Rossmann fold
AFONHELG_01675 3.7e-45
AFONHELG_01676 1.5e-253 L Transposase IS66 family
AFONHELG_01677 6e-29 S Transposase C of IS166 homeodomain
AFONHELG_01678 2e-16 XK27_01125 L IS66 Orf2 like protein
AFONHELG_01679 8.8e-18 XK27_01125 L IS66 Orf2 like protein
AFONHELG_01680 2.6e-17
AFONHELG_01681 1.6e-46 K Helix-turn-helix XRE-family like proteins
AFONHELG_01682 1.6e-42 K Helix-turn-helix XRE-family like proteins
AFONHELG_01683 1e-131
AFONHELG_01684 1.2e-64
AFONHELG_01685 2e-14 K Helix-turn-helix XRE-family like proteins
AFONHELG_01686 1.6e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AFONHELG_01688 1e-96 arbZ I Acyltransferase
AFONHELG_01689 0.0 treB G phosphotransferase system
AFONHELG_01690 1.2e-129 treR K UTRA
AFONHELG_01691 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
AFONHELG_01692 1.5e-272
AFONHELG_01693 6.2e-81
AFONHELG_01694 9.2e-180 S Bacteriocin helveticin-J
AFONHELG_01695 2.8e-290 M Peptidase family M1 domain
AFONHELG_01696 2.3e-176 S SLAP domain
AFONHELG_01697 2.2e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AFONHELG_01698 2.6e-54 S Psort location Cytoplasmic, score
AFONHELG_01700 3.3e-222 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AFONHELG_01701 6.5e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
AFONHELG_01702 7.7e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
AFONHELG_01703 1e-79 K response regulator
AFONHELG_01704 6.1e-63 sptS 2.7.13.3 T Histidine kinase
AFONHELG_01705 1.3e-115 sptS 2.7.13.3 T Histidine kinase
AFONHELG_01706 2.3e-207 EGP Major facilitator Superfamily
AFONHELG_01707 1.6e-70 O OsmC-like protein
AFONHELG_01708 7.2e-88 2.7.7.65 T phosphorelay sensor kinase activity
AFONHELG_01709 8.2e-132 cbiQ P Cobalt transport protein
AFONHELG_01710 4.3e-155 P ABC transporter
AFONHELG_01711 2.6e-149 cbiO2 P ABC transporter
AFONHELG_01712 3.3e-59 pdxH S Pyridoxamine 5'-phosphate oxidase
AFONHELG_01713 7.1e-229 steT E amino acid
AFONHELG_01714 1.7e-229 amd 3.5.1.47 E Peptidase family M20/M25/M40
AFONHELG_01715 1.4e-27 3.2.2.20 K acetyltransferase
AFONHELG_01716 2.4e-95
AFONHELG_01717 1.6e-12
AFONHELG_01718 8.9e-102 glvR K Helix-turn-helix domain, rpiR family
AFONHELG_01719 1.1e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
AFONHELG_01720 3.2e-15
AFONHELG_01721 2.4e-124
AFONHELG_01722 9.8e-236 S response to antibiotic
AFONHELG_01723 1.6e-132 cysA V ABC transporter, ATP-binding protein
AFONHELG_01724 0.0 V FtsX-like permease family
AFONHELG_01726 2.6e-166 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AFONHELG_01727 1.2e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AFONHELG_01728 3.2e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
AFONHELG_01729 2.7e-85 L PFAM transposase, IS4 family protein
AFONHELG_01730 1.1e-41 L PFAM transposase, IS4 family protein
AFONHELG_01731 3.3e-16 L Transposase
AFONHELG_01732 9.8e-71 L Transposase
AFONHELG_01733 9e-42 3.2.1.4 GH5,GH9 M domain protein
AFONHELG_01734 9.1e-229 pbuG S permease
AFONHELG_01735 4.8e-48 K helix_turn_helix, mercury resistance
AFONHELG_01736 1.1e-59 K helix_turn_helix, mercury resistance
AFONHELG_01737 5.6e-41 S cog cog1373
AFONHELG_01738 1.3e-140 S cog cog1373
AFONHELG_01739 2.8e-230 pbuG S permease
AFONHELG_01740 2.5e-144 cof S haloacid dehalogenase-like hydrolase
AFONHELG_01741 4.5e-126 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
AFONHELG_01742 3.9e-116 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
AFONHELG_01743 2.8e-20 ybbH_2 K rpiR family
AFONHELG_01745 1.2e-52 3.6.4.12 S PD-(D/E)XK nuclease family transposase
AFONHELG_01746 1.5e-138 S Uncharacterized protein conserved in bacteria (DUF2263)
AFONHELG_01747 1.5e-59
AFONHELG_01748 0.0 lhr L DEAD DEAH box helicase
AFONHELG_01749 6.1e-249 P P-loop Domain of unknown function (DUF2791)
AFONHELG_01750 3.2e-256 S TerB-C domain
AFONHELG_01751 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
AFONHELG_01753 6.4e-37
AFONHELG_01754 3.8e-34 4.1.1.44 S Carboxymuconolactone decarboxylase family
AFONHELG_01755 1.7e-57 4.1.1.44 S Carboxymuconolactone decarboxylase family
AFONHELG_01756 7.7e-26 4.1.1.44 S Carboxymuconolactone decarboxylase family
AFONHELG_01757 4.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AFONHELG_01758 3.7e-92 S LPXTG cell wall anchor motif
AFONHELG_01759 3e-26
AFONHELG_01760 1.4e-91 yagE E amino acid
AFONHELG_01761 8.8e-47
AFONHELG_01762 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AFONHELG_01763 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AFONHELG_01764 3.7e-233 cycA E Amino acid permease
AFONHELG_01765 2.3e-69 maa S transferase hexapeptide repeat
AFONHELG_01766 1.2e-79 K Transcriptional regulator
AFONHELG_01767 7.6e-64 manO S Domain of unknown function (DUF956)
AFONHELG_01768 1.2e-171 manN G system, mannose fructose sorbose family IID component
AFONHELG_01769 1.2e-133 manY G PTS system
AFONHELG_01770 1.8e-187 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
AFONHELG_01771 3.1e-47 rafA 3.2.1.22 G alpha-galactosidase
AFONHELG_01772 1.5e-170 rafA 3.2.1.22 G alpha-galactosidase
AFONHELG_01773 1.4e-33 rafA 3.2.1.22 G alpha-galactosidase
AFONHELG_01774 1.5e-90 scrA 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFONHELG_01775 1e-45 scrA 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFONHELG_01776 1e-146 scrA 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFONHELG_01777 3.2e-130 scrB 3.2.1.26 GH32 G invertase
AFONHELG_01778 9.7e-155 msmR7 K helix_turn_helix, arabinose operon control protein
AFONHELG_01779 5.2e-13
AFONHELG_01780 1.2e-10 pvuIIC K Cro/C1-type HTH DNA-binding domain
AFONHELG_01781 1.5e-38 L Type II restriction enzyme MunI
AFONHELG_01783 3.1e-25
AFONHELG_01784 5.2e-240 pyrP F Permease
AFONHELG_01785 2.3e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AFONHELG_01787 1.2e-258 emrY EGP Major facilitator Superfamily
AFONHELG_01788 2.6e-175 mdtG EGP Major facilitator Superfamily
AFONHELG_01789 1.7e-209 pepA E M42 glutamyl aminopeptidase
AFONHELG_01790 3.8e-309 ybiT S ABC transporter, ATP-binding protein
AFONHELG_01791 0.0 clpE O AAA domain (Cdc48 subfamily)
AFONHELG_01792 1.7e-156 S Alpha/beta hydrolase of unknown function (DUF915)
AFONHELG_01793 9.9e-209 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFONHELG_01794 7e-21 XK27_06785 V ABC transporter, ATP-binding protein
AFONHELG_01795 3.5e-94 XK27_06785 V ABC transporter, ATP-binding protein
AFONHELG_01796 2.5e-112 XK27_06780 V ABC transporter permease
AFONHELG_01797 3.5e-46 L PFAM Integrase, catalytic core
AFONHELG_01798 4.2e-156 psaA P Belongs to the bacterial solute-binding protein 9 family
AFONHELG_01799 1.9e-115 fhuC P ABC transporter
AFONHELG_01800 1.6e-127 znuB U ABC 3 transport family
AFONHELG_01801 2.7e-231 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFONHELG_01802 2.4e-42 lctP C L-lactate permease
AFONHELG_01803 3.7e-39 S Enterocin A Immunity
AFONHELG_01804 1.5e-23
AFONHELG_01805 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
AFONHELG_01806 2.5e-180 S AAA domain
AFONHELG_01807 1.1e-124 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AFONHELG_01808 5.5e-23
AFONHELG_01809 2.5e-161 czcD P cation diffusion facilitator family transporter
AFONHELG_01810 8.3e-125 pgm3 G Belongs to the phosphoglycerate mutase family
AFONHELG_01811 3.8e-153
AFONHELG_01812 2.5e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
AFONHELG_01813 1e-125 hipB K Helix-turn-helix
AFONHELG_01814 1.4e-152 I alpha/beta hydrolase fold
AFONHELG_01815 2.4e-107 yjbF S SNARE associated Golgi protein
AFONHELG_01816 6e-97 J Acetyltransferase (GNAT) domain
AFONHELG_01817 1.7e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AFONHELG_01819 3.3e-86 D CobQ CobB MinD ParA nucleotide binding domain protein
AFONHELG_01820 2.7e-08
AFONHELG_01821 1.8e-27 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
AFONHELG_01822 6.6e-21 L Transposase
AFONHELG_01823 2e-18 spaB S Lantibiotic biosynthesis dehydratase C-term
AFONHELG_01824 8.9e-25 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
AFONHELG_01826 1e-215 iscS 2.8.1.7 E Aminotransferase class V
AFONHELG_01827 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AFONHELG_01828 2.5e-36
AFONHELG_01829 1.3e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
AFONHELG_01830 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
AFONHELG_01831 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AFONHELG_01832 9.2e-99 gpsB D DivIVA domain protein
AFONHELG_01833 2.8e-45 ylmH S S4 domain protein
AFONHELG_01834 2.4e-212 V ABC-type multidrug transport system, ATPase and permease components
AFONHELG_01835 9.2e-69 S Putative adhesin
AFONHELG_01836 1.3e-58 ypaA S Protein of unknown function (DUF1304)
AFONHELG_01837 2.1e-86
AFONHELG_01838 2.4e-56
AFONHELG_01839 2.9e-116 S Fic/DOC family
AFONHELG_01840 1.7e-102
AFONHELG_01841 6.1e-208 EGP Major facilitator Superfamily
AFONHELG_01842 5.4e-135
AFONHELG_01843 2.3e-142 sufC O FeS assembly ATPase SufC
AFONHELG_01844 1.3e-200 sufD O FeS assembly protein SufD
AFONHELG_01845 2.1e-206 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AFONHELG_01846 2.7e-66 nifU C SUF system FeS assembly protein, NifU family
AFONHELG_01847 2.8e-268 sufB O assembly protein SufB
AFONHELG_01848 7.6e-44 yitW S Iron-sulfur cluster assembly protein
AFONHELG_01849 1.3e-52
AFONHELG_01850 6.6e-131
AFONHELG_01851 1.9e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AFONHELG_01852 2.2e-108 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AFONHELG_01853 5.3e-101 G Aldose 1-epimerase
AFONHELG_01854 3.9e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AFONHELG_01855 2.1e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AFONHELG_01856 0.0 XK27_08315 M Sulfatase
AFONHELG_01857 3e-262 S Fibronectin type III domain
AFONHELG_01858 2.8e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AFONHELG_01859 4.9e-52
AFONHELG_01861 3.9e-256 pepC 3.4.22.40 E aminopeptidase
AFONHELG_01862 2.3e-111 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
AFONHELG_01863 1e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AFONHELG_01864 4.1e-253 pepC 3.4.22.40 E aminopeptidase
AFONHELG_01865 5.1e-64 hsp O Belongs to the small heat shock protein (HSP20) family
AFONHELG_01866 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AFONHELG_01867 4.9e-114
AFONHELG_01869 3.4e-114 E Belongs to the SOS response-associated peptidase family
AFONHELG_01870 1.2e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
AFONHELG_01871 4.7e-90 comEB 3.5.4.12 F MafB19-like deaminase
AFONHELG_01872 1e-108 S TPM domain
AFONHELG_01873 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
AFONHELG_01874 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AFONHELG_01875 1.5e-146 tatD L hydrolase, TatD family
AFONHELG_01876 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AFONHELG_01877 1.4e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AFONHELG_01878 2.9e-38 veg S Biofilm formation stimulator VEG
AFONHELG_01879 5.5e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
AFONHELG_01880 9.7e-205 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AFONHELG_01881 5.8e-30 S SLAP domain
AFONHELG_01882 4.8e-67
AFONHELG_01883 6.9e-46
AFONHELG_01884 4.9e-09 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFONHELG_01885 1.2e-74 nrdI F Belongs to the NrdI family
AFONHELG_01886 4.5e-92
AFONHELG_01887 3.8e-279 S O-antigen ligase like membrane protein
AFONHELG_01888 1.5e-25
AFONHELG_01889 1.2e-94 gmk2 2.7.4.8 F Guanylate kinase homologues.
AFONHELG_01890 1.9e-95 M NlpC/P60 family
AFONHELG_01891 1.1e-58 S Archaea bacterial proteins of unknown function
AFONHELG_01892 1.2e-41 S Archaea bacterial proteins of unknown function
AFONHELG_01893 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFONHELG_01894 6.7e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AFONHELG_01895 8.1e-242 snf 2.7.11.1 KL domain protein
AFONHELG_01896 6.2e-38 snf 2.7.11.1 KL domain protein
AFONHELG_01897 1.6e-17 snf 2.7.11.1 KL domain protein
AFONHELG_01899 1.2e-76 yxkA S Phosphatidylethanolamine-binding protein
AFONHELG_01900 6.7e-243 yjjP S Putative threonine/serine exporter
AFONHELG_01901 6.3e-171 citR K Putative sugar-binding domain
AFONHELG_01902 4.7e-16
AFONHELG_01903 2.2e-66 S Domain of unknown function DUF1828
AFONHELG_01904 3.6e-94 S UPF0397 protein
AFONHELG_01905 2.2e-111 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AFONHELG_01906 5.3e-199 ydiM G Major Facilitator Superfamily
AFONHELG_01907 1.5e-155 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AFONHELG_01908 5.2e-44 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFONHELG_01909 4.8e-102 S Aldo keto reductase
AFONHELG_01910 2.3e-17 S Aldo keto reductase
AFONHELG_01911 5e-173 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
AFONHELG_01912 6.1e-55
AFONHELG_01913 1.4e-08
AFONHELG_01914 1.9e-09 C FMN_bind
AFONHELG_01917 6.5e-131 pfoS S Phosphotransferase system, EIIC
AFONHELG_01918 2.3e-255 slpX S SLAP domain
AFONHELG_01919 5.2e-93
AFONHELG_01922 1.1e-211
AFONHELG_01923 4.7e-123 gntR1 K UTRA
AFONHELG_01924 1.8e-55 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
AFONHELG_01925 7.4e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AFONHELG_01926 5e-157 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFONHELG_01927 7.2e-264 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
AFONHELG_01928 2.6e-13 malE G Bacterial extracellular solute-binding protein
AFONHELG_01929 1.1e-247 ade 3.5.4.2 F Adenine deaminase C-terminal domain
AFONHELG_01930 1.3e-140 potD2 P ABC transporter
AFONHELG_01931 7.4e-133 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AFONHELG_01932 5.4e-107 potC3 E Binding-protein-dependent transport system inner membrane component
AFONHELG_01933 1.2e-101 potB E Binding-protein-dependent transport system inner membrane component
AFONHELG_01935 1.1e-209 V ABC transporter transmembrane region
AFONHELG_01936 1e-105 L Resolvase, N terminal domain
AFONHELG_01937 1.1e-150 S Fic/DOC family
AFONHELG_01939 9.1e-179
AFONHELG_01940 7.1e-44
AFONHELG_01941 4.1e-270 ycaM E amino acid
AFONHELG_01942 2e-71 S haloacid dehalogenase-like hydrolase
AFONHELG_01943 1.4e-18 S haloacid dehalogenase-like hydrolase
AFONHELG_01944 2.3e-311 S SH3-like domain
AFONHELG_01945 1.4e-89 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AFONHELG_01946 5.7e-80 ntd 2.4.2.6 F Nucleoside
AFONHELG_01947 0.0 G Belongs to the glycosyl hydrolase 31 family
AFONHELG_01948 1.3e-31
AFONHELG_01949 1.7e-30 I alpha/beta hydrolase fold
AFONHELG_01950 1.7e-60 I alpha/beta hydrolase fold
AFONHELG_01951 4.6e-76 2.3.1.128 K Acetyltransferase (GNAT) domain
AFONHELG_01952 3.5e-97 4.2.1.53 S Myosin-crossreactive antigen
AFONHELG_01953 9e-104 4.2.1.53 S Myosin-crossreactive antigen
AFONHELG_01954 6.6e-50 4.2.1.53 S Myosin-crossreactive antigen
AFONHELG_01955 2e-91 yxdD K Bacterial regulatory proteins, tetR family
AFONHELG_01956 8.3e-239 emrY EGP Major facilitator Superfamily
AFONHELG_01959 2.1e-96 MA20_25245 K Acetyltransferase (GNAT) domain
AFONHELG_01960 9.6e-29 cspA K Cold shock protein
AFONHELG_01961 6.5e-142 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
AFONHELG_01963 8.4e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFONHELG_01964 7.3e-245 nhaC C Na H antiporter NhaC
AFONHELG_01965 1.2e-52
AFONHELG_01966 7.1e-119 ybhL S Belongs to the BI1 family
AFONHELG_01967 3e-114 S Protein of unknown function (DUF1211)
AFONHELG_01968 6.7e-170 yegS 2.7.1.107 G Lipid kinase
AFONHELG_01969 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFONHELG_01970 4.2e-259 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AFONHELG_01971 5.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFONHELG_01972 1.5e-206 camS S sex pheromone
AFONHELG_01973 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AFONHELG_01974 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
AFONHELG_01975 7.6e-104 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
AFONHELG_01977 3.1e-86 ydcK S Belongs to the SprT family
AFONHELG_01978 1.7e-136 M Glycosyltransferase sugar-binding region containing DXD motif
AFONHELG_01979 7.8e-258 epsU S Polysaccharide biosynthesis protein
AFONHELG_01980 5.6e-222 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
AFONHELG_01981 0.0 pacL 3.6.3.8 P P-type ATPase
AFONHELG_01982 1.7e-60 pacL 3.6.3.8 P P-type ATPase
AFONHELG_01983 2.9e-185 cggR K Putative sugar-binding domain
AFONHELG_01984 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AFONHELG_01985 7.9e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AFONHELG_01986 5.8e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AFONHELG_01987 2.4e-184 lacR K Transcriptional regulator
AFONHELG_01988 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
AFONHELG_01989 4.1e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
AFONHELG_01990 1.8e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AFONHELG_01991 2e-29
AFONHELG_01992 2.8e-09 S Oxidoreductase family, NAD-binding Rossmann fold
AFONHELG_01993 1.5e-33 S Oxidoreductase family, NAD-binding Rossmann fold
AFONHELG_01995 6.1e-61 oppA E ABC transporter substrate-binding protein
AFONHELG_01996 1.2e-147 cjaA ET ABC transporter substrate-binding protein
AFONHELG_01997 6.3e-118 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AFONHELG_01998 2.6e-86 P ABC transporter permease
AFONHELG_01999 3.2e-105 papP P ABC transporter, permease protein
AFONHELG_02000 9.3e-64 5.4.2.11 G Phosphoglycerate mutase family
AFONHELG_02001 7.9e-81 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
AFONHELG_02002 2.1e-119 XK27_07525 3.6.1.55 F NUDIX domain
AFONHELG_02003 8.7e-131 2.4.2.3 F Phosphorylase superfamily
AFONHELG_02004 1.6e-51 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
AFONHELG_02006 8e-79 K Acetyltransferase (GNAT) domain
AFONHELG_02007 7.9e-52
AFONHELG_02008 2.1e-24 lacS G Transporter
AFONHELG_02009 4.9e-46 lacS G Transporter
AFONHELG_02010 1.2e-141 lacS G Transporter
AFONHELG_02011 0.0 lacS G Transporter
AFONHELG_02012 3.3e-34 lacZ 3.2.1.23 G -beta-galactosidase
AFONHELG_02013 5.9e-124 lacZ 3.2.1.23 G -beta-galactosidase
AFONHELG_02014 1.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AFONHELG_02015 1.8e-281 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AFONHELG_02016 2.9e-204 csaB M Glycosyl transferases group 1
AFONHELG_02017 4.7e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
AFONHELG_02018 1.3e-69 S Alpha beta hydrolase
AFONHELG_02019 2.8e-88 K Acetyltransferase (GNAT) family
AFONHELG_02020 4.6e-252 gor 1.8.1.7 C Glutathione reductase
AFONHELG_02021 1.7e-204 malE G Bacterial extracellular solute-binding protein
AFONHELG_02022 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
AFONHELG_02023 1.2e-58
AFONHELG_02024 2.4e-85 S hydrolase
AFONHELG_02025 3.3e-11 2.7.13.3 T GHKL domain
AFONHELG_02026 8.4e-159 rssA S Phospholipase, patatin family
AFONHELG_02027 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
AFONHELG_02028 1.4e-250 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
AFONHELG_02029 1.6e-102 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AFONHELG_02030 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)