ORF_ID e_value Gene_name EC_number CAZy COGs Description
HDFOJLED_00001 1.2e-76 mraZ K Belongs to the MraZ family
HDFOJLED_00002 3.1e-181 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDFOJLED_00003 1.4e-54 ftsL D Cell division protein FtsL
HDFOJLED_00004 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HDFOJLED_00005 2.3e-176 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDFOJLED_00006 2.8e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDFOJLED_00007 2.3e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDFOJLED_00008 4.4e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDFOJLED_00009 2e-234 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDFOJLED_00010 1.6e-204 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDFOJLED_00011 4.8e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDFOJLED_00012 9e-47 yggT S YGGT family
HDFOJLED_00013 1.8e-147 ylmH S S4 domain protein
HDFOJLED_00014 5.8e-77 gpsB D DivIVA domain protein
HDFOJLED_00015 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDFOJLED_00016 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
HDFOJLED_00017 4.4e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HDFOJLED_00018 1e-37
HDFOJLED_00019 3.8e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDFOJLED_00020 7.8e-216 iscS 2.8.1.7 E Aminotransferase class V
HDFOJLED_00021 4.1e-56 XK27_04120 S Putative amino acid metabolism
HDFOJLED_00022 6.7e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDFOJLED_00023 7.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HDFOJLED_00024 1.4e-100 S Repeat protein
HDFOJLED_00025 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDFOJLED_00026 9.1e-107 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HDFOJLED_00027 1.7e-27 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HDFOJLED_00028 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDFOJLED_00029 4.2e-33 ykzG S Belongs to the UPF0356 family
HDFOJLED_00030 1.7e-99 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDFOJLED_00031 0.0 typA T GTP-binding protein TypA
HDFOJLED_00032 1.5e-206 ftsW D Belongs to the SEDS family
HDFOJLED_00033 8.7e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HDFOJLED_00034 8.5e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HDFOJLED_00035 2.7e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDFOJLED_00036 4.1e-192 ylbL T Belongs to the peptidase S16 family
HDFOJLED_00037 3.1e-82 comEA L Competence protein ComEA
HDFOJLED_00038 0.0 comEC S Competence protein ComEC
HDFOJLED_00039 4.8e-174 holA 2.7.7.7 L DNA polymerase III delta subunit
HDFOJLED_00040 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HDFOJLED_00041 7e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDFOJLED_00042 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDFOJLED_00043 2.4e-150
HDFOJLED_00044 4.7e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDFOJLED_00045 1.5e-207 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDFOJLED_00046 4.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDFOJLED_00047 5.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
HDFOJLED_00048 2.4e-273 yjeM E Amino Acid
HDFOJLED_00049 9.2e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDFOJLED_00050 7.2e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
HDFOJLED_00051 1.4e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDFOJLED_00052 3.6e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HDFOJLED_00053 4e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HDFOJLED_00054 2.7e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDFOJLED_00055 8.6e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDFOJLED_00056 1.8e-212 aspC 2.6.1.1 E Aminotransferase
HDFOJLED_00057 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDFOJLED_00058 4.5e-205 pbpX1 V Beta-lactamase
HDFOJLED_00059 5.3e-110 3.6.1.55 F NUDIX domain
HDFOJLED_00060 3.2e-300 I Protein of unknown function (DUF2974)
HDFOJLED_00061 8.3e-36 C FMN_bind
HDFOJLED_00062 4.3e-10
HDFOJLED_00063 6.1e-55
HDFOJLED_00064 1e-173 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HDFOJLED_00065 3.9e-170 S Aldo keto reductase
HDFOJLED_00066 4.5e-242 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDFOJLED_00067 2.8e-123 gmuR K UTRA
HDFOJLED_00068 4.9e-162 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HDFOJLED_00069 1.8e-192 add 3.5.4.2, 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HDFOJLED_00070 1.9e-234 pbuG S permease
HDFOJLED_00071 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HDFOJLED_00072 6.6e-42 S PAS domain
HDFOJLED_00073 1.3e-134 nirC P Formate/nitrite transporter
HDFOJLED_00074 4.4e-143 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HDFOJLED_00075 1.2e-54 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HDFOJLED_00076 7.5e-108 pncA Q Isochorismatase family
HDFOJLED_00077 1.1e-267 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDFOJLED_00078 5.4e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
HDFOJLED_00080 2.1e-72 S Iron-sulphur cluster biosynthesis
HDFOJLED_00081 1.2e-124 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDFOJLED_00082 7.2e-135 gmuR K UTRA
HDFOJLED_00083 5e-83 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDFOJLED_00084 1.1e-106 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDFOJLED_00085 2.7e-279 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDFOJLED_00086 2e-80 ypbG 2.7.1.2 GK ROK family
HDFOJLED_00087 7.7e-11 ypbG 2.7.1.2 GK ROK family
HDFOJLED_00088 1.6e-85 C nitroreductase
HDFOJLED_00089 1.7e-65 S Domain of unknown function (DUF4767)
HDFOJLED_00090 1.7e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDFOJLED_00091 6.6e-132 yitS S Uncharacterised protein, DegV family COG1307
HDFOJLED_00092 1.1e-98 3.6.1.27 I Acid phosphatase homologues
HDFOJLED_00093 2.5e-31 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDFOJLED_00094 5.2e-123 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDFOJLED_00096 1e-57 S PFAM Uncharacterised protein family UPF0150
HDFOJLED_00097 6.5e-249 yifK E Amino acid permease
HDFOJLED_00098 5.7e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDFOJLED_00099 2.4e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDFOJLED_00100 7.2e-16 ps301 K sequence-specific DNA binding
HDFOJLED_00101 0.0 aha1 P E1-E2 ATPase
HDFOJLED_00102 2.2e-162 metQ1 P Belongs to the nlpA lipoprotein family
HDFOJLED_00103 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDFOJLED_00104 8.4e-88 metI P ABC transporter permease
HDFOJLED_00105 1.9e-188 S cog cog1373
HDFOJLED_00106 1.7e-34
HDFOJLED_00107 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDFOJLED_00108 1.6e-263 frdC 1.3.5.4 C FAD binding domain
HDFOJLED_00109 3.6e-39 UW LPXTG-motif cell wall anchor domain protein
HDFOJLED_00111 1.1e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HDFOJLED_00112 6.4e-74 fhaB M Rib/alpha-like repeat
HDFOJLED_00113 2.1e-43
HDFOJLED_00114 1.3e-47
HDFOJLED_00115 1.9e-258 pepC 3.4.22.40 E Peptidase C1-like family
HDFOJLED_00116 4.4e-272 P Sodium:sulfate symporter transmembrane region
HDFOJLED_00117 1.3e-153 ydjP I Alpha/beta hydrolase family
HDFOJLED_00118 5.3e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HDFOJLED_00119 9.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
HDFOJLED_00120 8.2e-168 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HDFOJLED_00121 2.2e-290 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HDFOJLED_00122 4.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDFOJLED_00123 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HDFOJLED_00124 0.0 2.7.7.73, 2.7.7.80 H ThiF family
HDFOJLED_00125 1.8e-287 V ABC transporter transmembrane region
HDFOJLED_00126 2e-71 L Transposase and inactivated derivatives, IS30 family
HDFOJLED_00127 3.3e-217 yceI EGP Major facilitator Superfamily
HDFOJLED_00128 1.1e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
HDFOJLED_00129 6.4e-27 K Helix-turn-helix XRE-family like proteins
HDFOJLED_00130 1.4e-203 S Bacteriocin helveticin-J
HDFOJLED_00131 8e-244 slpX S SLAP domain
HDFOJLED_00132 3e-55 L Integrase
HDFOJLED_00133 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDFOJLED_00134 2.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDFOJLED_00135 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDFOJLED_00136 2.3e-122 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HDFOJLED_00137 7.9e-76 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDFOJLED_00138 8.3e-38 L Transposase and inactivated derivatives
HDFOJLED_00139 1.3e-156 L Integrase core domain
HDFOJLED_00140 3.2e-69 S Membrane transport protein
HDFOJLED_00141 9.3e-149 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDFOJLED_00142 0.0 helD 3.6.4.12 L DNA helicase
HDFOJLED_00143 1.7e-125 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HDFOJLED_00144 1.1e-126 pgm3 G Phosphoglycerate mutase family
HDFOJLED_00145 2.5e-11 S Archaea bacterial proteins of unknown function
HDFOJLED_00146 1.8e-93 M NlpC/P60 family
HDFOJLED_00147 9.4e-95 gmk2 2.7.4.8 F Guanylate kinase homologues.
HDFOJLED_00148 4.3e-25
HDFOJLED_00149 2.9e-279 S O-antigen ligase like membrane protein
HDFOJLED_00150 6.1e-217 G Major Facilitator Superfamily
HDFOJLED_00152 2.5e-144 cof S haloacid dehalogenase-like hydrolase
HDFOJLED_00153 1.1e-229 pbuG S permease
HDFOJLED_00154 2.2e-174 S cog cog1373
HDFOJLED_00155 4.8e-151 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HDFOJLED_00156 1.8e-116 dedA S SNARE-like domain protein
HDFOJLED_00157 2.2e-84 S Protein of unknown function (DUF1461)
HDFOJLED_00158 1.2e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDFOJLED_00159 3.3e-88 yutD S Protein of unknown function (DUF1027)
HDFOJLED_00160 1.4e-275 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HDFOJLED_00161 3.3e-55
HDFOJLED_00162 5.9e-255 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HDFOJLED_00163 1.1e-178 ccpA K catabolite control protein A
HDFOJLED_00164 2.2e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HDFOJLED_00165 2.6e-43
HDFOJLED_00166 3.3e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HDFOJLED_00167 8.2e-154 ykuT M mechanosensitive ion channel
HDFOJLED_00168 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDFOJLED_00169 4.5e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HDFOJLED_00170 8.5e-69 yslB S Protein of unknown function (DUF2507)
HDFOJLED_00171 8.4e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDFOJLED_00172 4.6e-54 trxA O Belongs to the thioredoxin family
HDFOJLED_00173 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDFOJLED_00174 1.4e-50 yrzB S Belongs to the UPF0473 family
HDFOJLED_00175 1e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDFOJLED_00176 9.7e-42 yrzL S Belongs to the UPF0297 family
HDFOJLED_00177 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDFOJLED_00178 1.2e-85
HDFOJLED_00179 7.1e-64
HDFOJLED_00180 8.9e-227 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDFOJLED_00181 4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HDFOJLED_00182 7.1e-214 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDFOJLED_00183 5.8e-285 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HDFOJLED_00184 3.8e-35 yajC U Preprotein translocase
HDFOJLED_00185 1.1e-184 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDFOJLED_00186 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDFOJLED_00187 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDFOJLED_00188 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDFOJLED_00189 9.4e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDFOJLED_00190 1.5e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDFOJLED_00191 7.4e-89
HDFOJLED_00192 3.9e-47
HDFOJLED_00193 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HDFOJLED_00194 9.1e-206 scrB 3.2.1.26 GH32 G invertase
HDFOJLED_00195 6.1e-72 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HDFOJLED_00197 3.2e-148 ydiM G Major facilitator superfamily
HDFOJLED_00198 1.4e-11 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDFOJLED_00199 7.2e-36 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
HDFOJLED_00200 6.8e-195 L Transposase and inactivated derivatives, IS30 family
HDFOJLED_00201 2.8e-183 P secondary active sulfate transmembrane transporter activity
HDFOJLED_00202 1.5e-95 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HDFOJLED_00203 2.4e-223 oxlT P Major Facilitator Superfamily
HDFOJLED_00204 9.5e-92 L Helix-turn-helix domain
HDFOJLED_00205 1.2e-103 L HTH-like domain
HDFOJLED_00206 4.4e-112
HDFOJLED_00207 2.1e-07 ohr O redox protein regulator of disulfide bond formation
HDFOJLED_00208 8.3e-165 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDFOJLED_00209 1.2e-46
HDFOJLED_00210 1.3e-159
HDFOJLED_00211 7.3e-68 L Transposase
HDFOJLED_00212 1.2e-25 L Transposase
HDFOJLED_00213 0.0 uvrA2 L ABC transporter
HDFOJLED_00214 1.2e-16 S Bacteriocin helveticin-J
HDFOJLED_00215 5.7e-135 S Bacteriocin helveticin-J
HDFOJLED_00216 3.8e-185 S SLAP domain
HDFOJLED_00217 6.2e-15
HDFOJLED_00218 5.4e-14
HDFOJLED_00219 1.1e-57
HDFOJLED_00222 8.2e-230 pbuG S permease
HDFOJLED_00223 7.5e-25 K helix_turn_helix, mercury resistance
HDFOJLED_00224 1.8e-84 K helix_turn_helix, mercury resistance
HDFOJLED_00225 3.9e-65 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDFOJLED_00228 2.9e-198 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDFOJLED_00229 2.8e-125 cas4 3.1.12.1 L Domain of unknown function DUF83
HDFOJLED_00230 9.3e-158 csd2 L CRISPR-associated protein Cas7
HDFOJLED_00231 0.0 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
HDFOJLED_00232 1.1e-143 cas5d S CRISPR-associated protein (Cas_Cas5)
HDFOJLED_00233 0.0 cas3 L Type III restriction enzyme, res subunit
HDFOJLED_00234 4.6e-238 purD 6.3.4.13 F Belongs to the GARS family
HDFOJLED_00235 4.1e-289 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HDFOJLED_00236 3.2e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDFOJLED_00237 1.2e-194 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HDFOJLED_00238 1.5e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDFOJLED_00239 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDFOJLED_00240 2.3e-119 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDFOJLED_00241 1.9e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDFOJLED_00242 3.9e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HDFOJLED_00243 1.1e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDFOJLED_00244 4.2e-78 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDFOJLED_00245 1.3e-309 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HDFOJLED_00246 1.3e-122 darA C Flavodoxin
HDFOJLED_00247 4.8e-141 qmcA O prohibitin homologues
HDFOJLED_00248 4.3e-52 L RelB antitoxin
HDFOJLED_00249 3.8e-20
HDFOJLED_00250 8.4e-195 S Bacteriocin helveticin-J
HDFOJLED_00251 7.9e-39 M Peptidase family M1 domain
HDFOJLED_00252 3.6e-142 M Peptidase family M1 domain
HDFOJLED_00253 7e-62 M Peptidase family M1 domain
HDFOJLED_00254 8.7e-176 S SLAP domain
HDFOJLED_00255 9.7e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HDFOJLED_00256 0.0 S SLAP domain
HDFOJLED_00257 3.3e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDFOJLED_00258 7.3e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HDFOJLED_00259 1e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDFOJLED_00260 8.3e-213 ecsB U ABC transporter
HDFOJLED_00261 3.9e-136 ecsA V ABC transporter, ATP-binding protein
HDFOJLED_00262 3.8e-54 higA K Helix-turn-helix XRE-family like proteins
HDFOJLED_00263 3.4e-79 hit FG Scavenger mRNA decapping enzyme C-term binding
HDFOJLED_00264 8e-28
HDFOJLED_00265 1.3e-154 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDFOJLED_00266 6.9e-43 KLT Protein kinase domain
HDFOJLED_00268 1.5e-29 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HDFOJLED_00269 3.4e-112 ybbL S ABC transporter, ATP-binding protein
HDFOJLED_00270 1.6e-129 ybbM S Uncharacterised protein family (UPF0014)
HDFOJLED_00271 1.8e-46 S Domain of unknown function (DUF4160)
HDFOJLED_00272 3.3e-39 XK27_08875 O Matrixin
HDFOJLED_00273 5.1e-177 clcA P chloride
HDFOJLED_00276 4.9e-136 M NlpC/P60 family
HDFOJLED_00277 9.8e-21 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HDFOJLED_00278 1.3e-96 E Amino acid permease
HDFOJLED_00279 4.7e-160 E Amino acid permease
HDFOJLED_00280 3.6e-151 xerD L Phage integrase, N-terminal SAM-like domain
HDFOJLED_00281 1.2e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDFOJLED_00282 1.2e-241 amtB P ammonium transporter
HDFOJLED_00283 1.7e-85 L Resolvase, N terminal domain
HDFOJLED_00284 2.1e-48
HDFOJLED_00285 5.1e-47
HDFOJLED_00286 6.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HDFOJLED_00287 6.7e-114 hlyIII S protein, hemolysin III
HDFOJLED_00288 2.9e-148 DegV S Uncharacterised protein, DegV family COG1307
HDFOJLED_00289 9.3e-36 yozE S Belongs to the UPF0346 family
HDFOJLED_00290 6.8e-279 yjcE P Sodium proton antiporter
HDFOJLED_00291 1.2e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDFOJLED_00292 3.7e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDFOJLED_00293 3.7e-141 dprA LU DNA protecting protein DprA
HDFOJLED_00294 3e-87 L Belongs to the 'phage' integrase family
HDFOJLED_00295 9.5e-43 S Psort location CytoplasmicMembrane, score
HDFOJLED_00297 3.7e-19 S Pfam:Peptidase_M78
HDFOJLED_00298 3.4e-21 ps115 K sequence-specific DNA binding
HDFOJLED_00299 6.3e-14
HDFOJLED_00300 1.5e-71 ps308 K AntA/AntB antirepressor
HDFOJLED_00307 2.2e-69 S AAA domain
HDFOJLED_00308 5.1e-142 res L Helicase C-terminal domain protein
HDFOJLED_00309 2.2e-09
HDFOJLED_00310 3.8e-22 S HNH endonuclease
HDFOJLED_00311 3.2e-29 S Protein of unknown function (DUF669)
HDFOJLED_00312 2.3e-259 S Phage plasmid primase, P4
HDFOJLED_00313 6.5e-07
HDFOJLED_00314 1.9e-40 S VRR-NUC domain
HDFOJLED_00316 2e-07
HDFOJLED_00317 2.4e-27
HDFOJLED_00319 5.3e-21 S HNH endonuclease
HDFOJLED_00320 2.2e-41 L Phage terminase, small subunit
HDFOJLED_00322 1.2e-18 V HNH endonuclease
HDFOJLED_00323 2e-216 S Phage Terminase
HDFOJLED_00325 1.6e-112 S Phage portal protein
HDFOJLED_00326 1.7e-75 S Clp protease
HDFOJLED_00327 2.1e-121 S peptidase activity
HDFOJLED_00328 2.6e-18 S Phage gp6-like head-tail connector protein
HDFOJLED_00330 3.9e-09 S exonuclease activity
HDFOJLED_00332 7e-15 S Pfam:Phage_TTP_1
HDFOJLED_00335 4.2e-170 xkdO D NLP P60 protein
HDFOJLED_00336 6.5e-33 S phage tail
HDFOJLED_00339 2.8e-257 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HDFOJLED_00340 3.9e-208 EGP Major facilitator Superfamily
HDFOJLED_00341 4.4e-08 ropB K Transcriptional regulator
HDFOJLED_00342 2.8e-40 EGP Major facilitator Superfamily
HDFOJLED_00343 3.9e-155 EGP Major facilitator Superfamily
HDFOJLED_00344 9.6e-269 L COG2963 Transposase and inactivated derivatives
HDFOJLED_00345 1.7e-154 glcU U sugar transport
HDFOJLED_00346 2.1e-64 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDFOJLED_00347 2.9e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDFOJLED_00348 5.5e-29 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HDFOJLED_00349 4e-11 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDFOJLED_00350 1.2e-74 nrdI F Belongs to the NrdI family
HDFOJLED_00351 1.1e-94
HDFOJLED_00357 4.2e-101
HDFOJLED_00358 2.8e-282 lsa S ABC transporter
HDFOJLED_00359 3e-303
HDFOJLED_00360 1.4e-80
HDFOJLED_00361 5.4e-109 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDFOJLED_00362 4.7e-66 S ASCH domain
HDFOJLED_00363 1.9e-37 4.4.1.5 E lactoylglutathione lyase activity
HDFOJLED_00364 9.6e-55
HDFOJLED_00365 1.1e-28
HDFOJLED_00366 2.5e-49 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
HDFOJLED_00367 1.4e-170 yobV1 K WYL domain
HDFOJLED_00368 5.3e-68 S pyridoxamine 5-phosphate
HDFOJLED_00369 2.2e-262 npr 1.11.1.1 C NADH oxidase
HDFOJLED_00370 1.7e-20 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HDFOJLED_00371 1.7e-49 mepA V MATE efflux family protein
HDFOJLED_00372 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HDFOJLED_00373 3.6e-32 copZ C Heavy-metal-associated domain
HDFOJLED_00374 1e-88 dps P Belongs to the Dps family
HDFOJLED_00375 2e-109 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HDFOJLED_00376 4.7e-53 K Acetyltransferase (GNAT) family
HDFOJLED_00377 5.3e-71
HDFOJLED_00378 8e-237 S Protein of unknown function DUF262
HDFOJLED_00379 2.2e-105 S Putative inner membrane protein (DUF1819)
HDFOJLED_00380 6e-111 S Domain of unknown function (DUF1788)
HDFOJLED_00381 2.3e-216 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
HDFOJLED_00382 0.0 2.1.1.72 LV Eco57I restriction-modification methylase
HDFOJLED_00383 8.4e-102 LO the current gene model (or a revised gene model) may contain a frame shift
HDFOJLED_00384 0.0 S PglZ domain
HDFOJLED_00385 0.0
HDFOJLED_00386 7.9e-24 L PFAM transposase, IS4 family protein
HDFOJLED_00387 1.2e-32 L Transposase and inactivated derivatives, IS30 family
HDFOJLED_00388 1.6e-45
HDFOJLED_00389 1.9e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDFOJLED_00390 8.8e-22
HDFOJLED_00391 6.2e-18
HDFOJLED_00392 1.1e-32 traI 5.99.1.2 L C-terminal repeat of topoisomerase
HDFOJLED_00393 1e-116 G phosphoglycerate mutase
HDFOJLED_00394 5e-142 L COG3547 Transposase and inactivated derivatives
HDFOJLED_00395 4.2e-10
HDFOJLED_00407 4.9e-116 L COG2963 Transposase and inactivated derivatives
HDFOJLED_00408 7.7e-19 D Alpha beta
HDFOJLED_00409 4.2e-46
HDFOJLED_00410 1.8e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HDFOJLED_00411 3.3e-217 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HDFOJLED_00412 4.6e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HDFOJLED_00413 2.7e-74 L transposase, IS605 OrfB family
HDFOJLED_00414 5.8e-99 L transposase, IS605 OrfB family
HDFOJLED_00415 5.2e-15 L transposase, IS605 OrfB family
HDFOJLED_00416 1.2e-166 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDFOJLED_00417 8.3e-152 yihY S Belongs to the UPF0761 family
HDFOJLED_00418 1.9e-163 map 3.4.11.18 E Methionine Aminopeptidase
HDFOJLED_00419 1.6e-79 fld C Flavodoxin
HDFOJLED_00420 1.8e-87 gtcA S Teichoic acid glycosylation protein
HDFOJLED_00421 3.8e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HDFOJLED_00422 2.7e-25
HDFOJLED_00424 3.9e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDFOJLED_00425 3.7e-208 yfmL 3.6.4.13 L DEAD DEAH box helicase
HDFOJLED_00426 7.5e-129 M Glycosyl hydrolases family 25
HDFOJLED_00427 1.3e-227 potE E amino acid
HDFOJLED_00428 4.9e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HDFOJLED_00429 5e-238 yhdP S Transporter associated domain
HDFOJLED_00430 1.5e-30 C nitroreductase
HDFOJLED_00431 1.5e-14 C nitroreductase
HDFOJLED_00432 1.6e-39
HDFOJLED_00433 4.2e-86 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDFOJLED_00434 1.9e-73
HDFOJLED_00435 1.8e-136 glvR K Helix-turn-helix domain, rpiR family
HDFOJLED_00436 0.0 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HDFOJLED_00437 2.2e-86 S hydrolase
HDFOJLED_00438 3.3e-11 2.7.13.3 T GHKL domain
HDFOJLED_00439 2.6e-160 rssA S Phospholipase, patatin family
HDFOJLED_00440 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HDFOJLED_00441 7.1e-133 glcR K DeoR C terminal sensor domain
HDFOJLED_00442 5.4e-62 S Enterocin A Immunity
HDFOJLED_00443 6.2e-54 yitW S Iron-sulfur cluster assembly protein
HDFOJLED_00444 1.9e-272 sufB O assembly protein SufB
HDFOJLED_00445 4.2e-80 nifU C SUF system FeS assembly protein, NifU family
HDFOJLED_00446 1.5e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDFOJLED_00447 3.2e-226 sufD O FeS assembly protein SufD
HDFOJLED_00448 1e-145 sufC O FeS assembly ATPase SufC
HDFOJLED_00449 1.6e-67
HDFOJLED_00450 5.1e-84 repA S Replication initiator protein A
HDFOJLED_00451 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDFOJLED_00452 2.9e-54 S Protein of unknown function (DUF3397)
HDFOJLED_00453 6.5e-13 S Protein of unknown function (DUF4044)
HDFOJLED_00454 6.6e-107 S Uncharacterised protein family (UPF0236)
HDFOJLED_00455 4.4e-28
HDFOJLED_00456 0.0 S SH3-like domain
HDFOJLED_00457 7.5e-133 S haloacid dehalogenase-like hydrolase
HDFOJLED_00458 2.3e-270 ycaM E amino acid
HDFOJLED_00459 8.2e-161
HDFOJLED_00460 9e-77
HDFOJLED_00462 3.6e-188 cggR K Putative sugar-binding domain
HDFOJLED_00463 8.4e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDFOJLED_00464 9.3e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HDFOJLED_00465 1.2e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDFOJLED_00466 1.8e-95
HDFOJLED_00467 4.8e-157 ycsE S Sucrose-6F-phosphate phosphohydrolase
HDFOJLED_00468 3.3e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDFOJLED_00469 1.8e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HDFOJLED_00470 6.4e-90 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HDFOJLED_00471 1.4e-98 dnaQ 2.7.7.7 L DNA polymerase III
HDFOJLED_00472 1.1e-164 murB 1.3.1.98 M Cell wall formation
HDFOJLED_00473 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDFOJLED_00474 5.1e-129 potB P ABC transporter permease
HDFOJLED_00475 1.7e-132 potC P ABC transporter permease
HDFOJLED_00476 5.6e-208 potD P ABC transporter
HDFOJLED_00477 4.2e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDFOJLED_00478 2.4e-170 ybbR S YbbR-like protein
HDFOJLED_00479 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDFOJLED_00480 2.6e-149 S hydrolase
HDFOJLED_00481 3.8e-148 S Sucrose-6F-phosphate phosphohydrolase
HDFOJLED_00482 1.8e-117
HDFOJLED_00483 9.9e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDFOJLED_00484 7.8e-216 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HDFOJLED_00485 7e-142 licT K CAT RNA binding domain
HDFOJLED_00486 0.0 bglP G phosphotransferase system
HDFOJLED_00487 1.3e-22 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDFOJLED_00488 9.6e-263 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDFOJLED_00489 4.2e-183 D Alpha beta
HDFOJLED_00490 2.1e-288 E Amino acid permease
HDFOJLED_00492 2.2e-63 L COG3547 Transposase and inactivated derivatives
HDFOJLED_00493 6.3e-84 L COG2826 Transposase and inactivated derivatives, IS30 family
HDFOJLED_00494 3.1e-77 L Probable transposase
HDFOJLED_00495 1.4e-56 repA S Replication initiator protein A (RepA) N-terminus
HDFOJLED_00497 1.4e-68 L An automated process has identified a potential problem with this gene model
HDFOJLED_00498 1.8e-167 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HDFOJLED_00499 1.8e-136 fruR K DeoR C terminal sensor domain
HDFOJLED_00502 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HDFOJLED_00503 1.5e-26
HDFOJLED_00504 2.1e-32
HDFOJLED_00505 1.5e-33 yozG K Transcriptional regulator
HDFOJLED_00506 7.9e-29 S Enterocin A Immunity
HDFOJLED_00507 1.4e-211 S Archaea bacterial proteins of unknown function
HDFOJLED_00508 7.2e-146 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HDFOJLED_00509 3.2e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDFOJLED_00510 9.2e-209 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HDFOJLED_00511 5.1e-122 K response regulator
HDFOJLED_00512 0.0 V ABC transporter
HDFOJLED_00513 4.2e-298 V ABC transporter, ATP-binding protein
HDFOJLED_00514 2e-138 XK27_01040 S Protein of unknown function (DUF1129)
HDFOJLED_00515 6.1e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDFOJLED_00516 3.7e-44 yyzM S Bacterial protein of unknown function (DUF951)
HDFOJLED_00517 8.5e-154 spo0J K Belongs to the ParB family
HDFOJLED_00518 1.9e-136 soj D Sporulation initiation inhibitor
HDFOJLED_00519 3.9e-148 noc K Belongs to the ParB family
HDFOJLED_00520 1.8e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HDFOJLED_00521 7.3e-84 cvpA S Colicin V production protein
HDFOJLED_00522 1.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDFOJLED_00523 2.8e-148 3.1.3.48 T Tyrosine phosphatase family
HDFOJLED_00524 3.5e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
HDFOJLED_00525 1.9e-95 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HDFOJLED_00526 3.1e-110 K WHG domain
HDFOJLED_00527 8e-38
HDFOJLED_00528 1.8e-275 pipD E Dipeptidase
HDFOJLED_00529 1.2e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HDFOJLED_00530 2.6e-165 hrtB V ABC transporter permease
HDFOJLED_00531 2.2e-93 ygfC K Bacterial regulatory proteins, tetR family
HDFOJLED_00532 1.2e-111 G phosphoglycerate mutase
HDFOJLED_00533 6.6e-139 aroD S Alpha/beta hydrolase family
HDFOJLED_00534 6.4e-142 S Belongs to the UPF0246 family
HDFOJLED_00535 1.2e-120
HDFOJLED_00536 3.1e-49 2.7.7.12 C Domain of unknown function (DUF4931)
HDFOJLED_00537 8.8e-29 L PFAM transposase, IS4 family protein
HDFOJLED_00538 1.5e-64 L An automated process has identified a potential problem with this gene model
HDFOJLED_00539 1.6e-20
HDFOJLED_00540 6e-54 L An automated process has identified a potential problem with this gene model
HDFOJLED_00541 6.6e-31 L COG2963 Transposase and inactivated derivatives
HDFOJLED_00542 3.6e-231 V ABC-type multidrug transport system, ATPase and permease components
HDFOJLED_00543 1.7e-19 V ABC-type multidrug transport system, ATPase and permease components
HDFOJLED_00545 1.4e-33
HDFOJLED_00547 2.2e-131 K response regulator
HDFOJLED_00548 2e-306 vicK 2.7.13.3 T Histidine kinase
HDFOJLED_00549 6.7e-243 yycH S YycH protein
HDFOJLED_00550 2.7e-146 yycI S YycH protein
HDFOJLED_00551 5.7e-149 vicX 3.1.26.11 S domain protein
HDFOJLED_00552 3.3e-180 htrA 3.4.21.107 O serine protease
HDFOJLED_00553 4.3e-91 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDFOJLED_00554 5.6e-38 K Helix-turn-helix XRE-family like proteins
HDFOJLED_00555 8.8e-25 K Helix-turn-helix XRE-family like proteins
HDFOJLED_00557 8.5e-20 V ATPases associated with a variety of cellular activities
HDFOJLED_00558 1.7e-53 V ATPases associated with a variety of cellular activities
HDFOJLED_00559 9.2e-40
HDFOJLED_00560 5.6e-30 higA K Helix-turn-helix XRE-family like proteins
HDFOJLED_00561 7.6e-168 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HDFOJLED_00562 1.3e-90 P Cobalt transport protein
HDFOJLED_00563 1.4e-245 cbiO1 S ABC transporter, ATP-binding protein
HDFOJLED_00564 1.9e-172 K helix_turn_helix, arabinose operon control protein
HDFOJLED_00565 2.6e-169 L hmm pf00665
HDFOJLED_00566 2.1e-104 L Helix-turn-helix domain
HDFOJLED_00567 3.9e-162 htpX O Belongs to the peptidase M48B family
HDFOJLED_00568 2.3e-96 lemA S LemA family
HDFOJLED_00569 7.4e-167 ybiR P Citrate transporter
HDFOJLED_00570 7.7e-70 S Iron-sulphur cluster biosynthesis
HDFOJLED_00571 1.1e-232 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HDFOJLED_00572 3.3e-61 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HDFOJLED_00573 1.2e-17
HDFOJLED_00574 2.4e-121 yfbR S HD containing hydrolase-like enzyme
HDFOJLED_00575 1.2e-160 L HNH nucleases
HDFOJLED_00576 1.4e-136 glnQ E ABC transporter, ATP-binding protein
HDFOJLED_00577 1.1e-287 glnP P ABC transporter permease
HDFOJLED_00578 1.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HDFOJLED_00579 1.8e-62 yeaO S Protein of unknown function, DUF488
HDFOJLED_00580 2.5e-120 terC P Integral membrane protein TerC family
HDFOJLED_00581 3.5e-91 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HDFOJLED_00582 5e-23 repA S Replication initiator protein A
HDFOJLED_00583 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDFOJLED_00584 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDFOJLED_00585 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDFOJLED_00586 2.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
HDFOJLED_00588 1.6e-08
HDFOJLED_00589 5.7e-28
HDFOJLED_00591 1.3e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HDFOJLED_00592 1.1e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDFOJLED_00593 5e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDFOJLED_00594 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDFOJLED_00595 1.2e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDFOJLED_00596 2.2e-60 yabR J S1 RNA binding domain
HDFOJLED_00597 5.8e-59 divIC D Septum formation initiator
HDFOJLED_00598 1.8e-34 yabO J S4 domain protein
HDFOJLED_00599 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDFOJLED_00600 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDFOJLED_00601 7.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HDFOJLED_00602 2.4e-127 S (CBS) domain
HDFOJLED_00603 2.9e-92 K transcriptional regulator
HDFOJLED_00604 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDFOJLED_00605 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDFOJLED_00606 5.5e-246 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDFOJLED_00607 1e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDFOJLED_00608 1.3e-38 rpmE2 J Ribosomal protein L31
HDFOJLED_00609 1.6e-157 S Sucrose-6F-phosphate phosphohydrolase
HDFOJLED_00610 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HDFOJLED_00611 0.0 pepO 3.4.24.71 O Peptidase family M13
HDFOJLED_00612 3.3e-59 pdxH S Pyridoxamine 5'-phosphate oxidase
HDFOJLED_00613 4.4e-231 steT E amino acid
HDFOJLED_00614 6.8e-231 amd 3.5.1.47 E Peptidase family M20/M25/M40
HDFOJLED_00615 5.6e-158 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HDFOJLED_00616 8.2e-228 mmuP E amino acid
HDFOJLED_00617 3.4e-241 N Uncharacterized conserved protein (DUF2075)
HDFOJLED_00618 1.4e-27 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HDFOJLED_00619 1.3e-53 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HDFOJLED_00620 2.2e-68 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HDFOJLED_00621 2.2e-207
HDFOJLED_00622 7.1e-257 S C4-dicarboxylate anaerobic carrier
HDFOJLED_00623 7.4e-92 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HDFOJLED_00624 4.7e-102 S LexA-binding, inner membrane-associated putative hydrolase
HDFOJLED_00625 3e-37
HDFOJLED_00626 2.1e-121 malY 4.4.1.8 E Aminotransferase, class I
HDFOJLED_00627 1.2e-37 malY 4.4.1.8 E Aminotransferase, class I
HDFOJLED_00628 2.6e-55
HDFOJLED_00629 2.2e-45 brnQ U Component of the transport system for branched-chain amino acids
HDFOJLED_00630 5.4e-176 brnQ U Component of the transport system for branched-chain amino acids
HDFOJLED_00631 2e-68 S Protein of unknown function (DUF554)
HDFOJLED_00632 1.2e-13 S Protein of unknown function (DUF554)
HDFOJLED_00633 4.5e-45 K LysR substrate binding domain
HDFOJLED_00634 1.9e-243 ubiX 2.5.1.129, 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HDFOJLED_00635 5.3e-28 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HDFOJLED_00636 6.5e-22
HDFOJLED_00637 3.7e-82 tdh 1.1.1.14 C Zinc-binding dehydrogenase
HDFOJLED_00638 2.2e-85 tdh 1.1.1.14 C Zinc-binding dehydrogenase
HDFOJLED_00640 1.9e-67 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HDFOJLED_00641 3e-68 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HDFOJLED_00642 1.4e-43 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HDFOJLED_00643 6.5e-273 pepV 3.5.1.18 E dipeptidase PepV
HDFOJLED_00644 5.3e-189 V Beta-lactamase
HDFOJLED_00645 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HDFOJLED_00646 9.6e-47
HDFOJLED_00647 5e-90
HDFOJLED_00648 4.6e-88 XK27_09675 K Acetyltransferase (GNAT) domain
HDFOJLED_00649 3e-53 S Protein of unknown function (DUF3021)
HDFOJLED_00650 1.6e-76 K LytTr DNA-binding domain
HDFOJLED_00651 3.1e-38
HDFOJLED_00652 8e-125 magIII L Base excision DNA repair protein, HhH-GPD family
HDFOJLED_00653 2e-22 K Helix-turn-helix XRE-family like proteins
HDFOJLED_00654 2.5e-22
HDFOJLED_00655 8.9e-140 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HDFOJLED_00656 6.7e-229 yrvN L AAA C-terminal domain
HDFOJLED_00657 2.1e-32
HDFOJLED_00658 9.1e-71 fabK 1.3.1.9 S Nitronate monooxygenase
HDFOJLED_00659 1.5e-84 kptA H Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HDFOJLED_00660 8.5e-66 S Abi-like protein
HDFOJLED_00662 1e-125 4.1.1.45 S Amidohydrolase
HDFOJLED_00663 3e-94 lacA 2.3.1.79 S Maltose acetyltransferase
HDFOJLED_00664 7.8e-100 G Antibiotic biosynthesis monooxygenase
HDFOJLED_00665 1.4e-26 S Uncharacterized protein conserved in bacteria (DUF2255)
HDFOJLED_00666 1e-69 adhR K helix_turn_helix, mercury resistance
HDFOJLED_00667 6e-112 papP P ABC transporter, permease protein
HDFOJLED_00668 3.1e-87 P ABC transporter permease
HDFOJLED_00669 5.3e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDFOJLED_00670 1.7e-159 cjaA ET ABC transporter substrate-binding protein
HDFOJLED_00671 9.5e-124 L Helix-turn-helix domain
HDFOJLED_00672 2.2e-123 L hmm pf00665
HDFOJLED_00674 9.9e-117 L Integrase
HDFOJLED_00676 2.2e-254 gor 1.8.1.7 C Glutathione reductase
HDFOJLED_00677 7.4e-31 K Acetyltransferase (GNAT) family
HDFOJLED_00678 1e-57 S Alpha beta hydrolase
HDFOJLED_00679 6.1e-18 S Hydrolases of the alpha beta superfamily
HDFOJLED_00680 2.1e-39 S Hydrolases of the alpha beta superfamily
HDFOJLED_00681 2.9e-142 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HDFOJLED_00682 4.5e-46 1.1.1.3 T phosphoserine phosphatase activity
HDFOJLED_00683 1.9e-83 K Bacterial regulatory proteins, tetR family
HDFOJLED_00684 1.4e-107 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HDFOJLED_00685 1.5e-39 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HDFOJLED_00686 2.4e-45 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HDFOJLED_00687 9.4e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HDFOJLED_00688 7.6e-94 K acetyltransferase
HDFOJLED_00689 1.2e-85 dps P Belongs to the Dps family
HDFOJLED_00690 3e-255 snf 2.7.11.1 KL domain protein
HDFOJLED_00691 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDFOJLED_00692 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDFOJLED_00693 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDFOJLED_00694 3.8e-171 K Transcriptional regulator
HDFOJLED_00695 3.3e-164 ppaC 3.6.1.1 C inorganic pyrophosphatase
HDFOJLED_00696 5.9e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDFOJLED_00697 6.2e-55 K Helix-turn-helix domain
HDFOJLED_00698 8.9e-88 yoaK S Protein of unknown function (DUF1275)
HDFOJLED_00699 3.6e-265 pepC 3.4.22.40 E Peptidase C1-like family
HDFOJLED_00700 1.1e-145 glcU U sugar transport
HDFOJLED_00701 2.3e-09
HDFOJLED_00702 0.0 mgtA 3.6.3.2, 3.6.3.6 P COG0474 Cation transport ATPase
HDFOJLED_00703 2.1e-114 L transposase, IS605 OrfB family
HDFOJLED_00704 6.2e-105 L transposase, IS605 OrfB family
HDFOJLED_00705 1.6e-182 S AAA domain
HDFOJLED_00706 8.3e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDFOJLED_00707 5.5e-23
HDFOJLED_00708 6e-163 czcD P cation diffusion facilitator family transporter
HDFOJLED_00709 2e-126 pgm3 G Belongs to the phosphoglycerate mutase family
HDFOJLED_00710 1.9e-133 S membrane transporter protein
HDFOJLED_00711 2.7e-112 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HDFOJLED_00712 3e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HDFOJLED_00713 5.5e-47 S Protein of unknown function (DUF805)
HDFOJLED_00714 1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
HDFOJLED_00715 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDFOJLED_00716 6e-143 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDFOJLED_00717 1.8e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDFOJLED_00718 3.4e-149 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDFOJLED_00719 1.7e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDFOJLED_00720 4e-60 rplQ J Ribosomal protein L17
HDFOJLED_00721 1.8e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDFOJLED_00722 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDFOJLED_00723 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDFOJLED_00724 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HDFOJLED_00725 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDFOJLED_00726 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDFOJLED_00727 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDFOJLED_00728 1.5e-71 rplO J Binds to the 23S rRNA
HDFOJLED_00729 2.3e-24 rpmD J Ribosomal protein L30
HDFOJLED_00730 1.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDFOJLED_00731 2.8e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDFOJLED_00732 9.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDFOJLED_00733 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDFOJLED_00734 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDFOJLED_00735 3.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDFOJLED_00736 6.3e-32 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDFOJLED_00737 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDFOJLED_00738 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDFOJLED_00739 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HDFOJLED_00740 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDFOJLED_00741 5.4e-108 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDFOJLED_00742 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDFOJLED_00743 9.3e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDFOJLED_00744 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDFOJLED_00745 4.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDFOJLED_00746 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
HDFOJLED_00747 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDFOJLED_00748 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HDFOJLED_00749 1.9e-109 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HDFOJLED_00750 3.4e-100 G Aldose 1-epimerase
HDFOJLED_00751 1.2e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDFOJLED_00752 2.5e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDFOJLED_00753 0.0 XK27_08315 M Sulfatase
HDFOJLED_00754 9.9e-266 S Fibronectin type III domain
HDFOJLED_00755 9.7e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDFOJLED_00756 5.4e-21
HDFOJLED_00758 6.1e-257 pepC 3.4.22.40 E aminopeptidase
HDFOJLED_00759 2.1e-117 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDFOJLED_00760 2.2e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDFOJLED_00761 8.8e-256 pepC 3.4.22.40 E aminopeptidase
HDFOJLED_00762 2.6e-68 hsp O Belongs to the small heat shock protein (HSP20) family
HDFOJLED_00763 1.8e-75 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDFOJLED_00764 4.9e-114
HDFOJLED_00766 4.5e-114 E Belongs to the SOS response-associated peptidase family
HDFOJLED_00767 1.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDFOJLED_00768 5.5e-91 comEB 3.5.4.12 F MafB19-like deaminase
HDFOJLED_00769 4.6e-109 S TPM domain
HDFOJLED_00770 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HDFOJLED_00771 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDFOJLED_00772 1e-147 tatD L hydrolase, TatD family
HDFOJLED_00773 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDFOJLED_00774 7.9e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDFOJLED_00775 5e-38 veg S Biofilm formation stimulator VEG
HDFOJLED_00776 2.2e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HDFOJLED_00777 2.1e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDFOJLED_00781 2e-13 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HDFOJLED_00782 8.9e-75 tnpR L Resolvase, N terminal domain
HDFOJLED_00783 1.8e-130 S Phage Mu protein F like protein
HDFOJLED_00784 1.2e-12 ytgB S Transglycosylase associated protein
HDFOJLED_00785 7.5e-123 tnp L DDE domain
HDFOJLED_00786 3.4e-56 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HDFOJLED_00787 4.9e-90 L Transposase DDE domain
HDFOJLED_00788 1.6e-25 L Transposase DDE domain
HDFOJLED_00791 7.6e-157 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HDFOJLED_00792 7e-162 dnaQ 2.7.7.7 L EXOIII
HDFOJLED_00793 8.5e-159 endA F DNA RNA non-specific endonuclease
HDFOJLED_00794 5e-281 pipD E Dipeptidase
HDFOJLED_00795 3.9e-201 malK P ATPases associated with a variety of cellular activities
HDFOJLED_00796 2.1e-157 gtsB P ABC-type sugar transport systems, permease components
HDFOJLED_00797 4.7e-146 gtsC P Binding-protein-dependent transport system inner membrane component
HDFOJLED_00798 3.5e-257 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HDFOJLED_00799 1.8e-240 G Bacterial extracellular solute-binding protein
HDFOJLED_00800 2e-158 corA P CorA-like Mg2+ transporter protein
HDFOJLED_00801 1e-157 3.5.2.6 V Beta-lactamase enzyme family
HDFOJLED_00802 3.3e-98 yobS K Bacterial regulatory proteins, tetR family
HDFOJLED_00803 0.0 ydgH S MMPL family
HDFOJLED_00804 3.3e-149
HDFOJLED_00805 2.5e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HDFOJLED_00806 1.7e-125 hipB K Helix-turn-helix
HDFOJLED_00807 1.3e-153 I alpha/beta hydrolase fold
HDFOJLED_00808 5.4e-107 yjbF S SNARE associated Golgi protein
HDFOJLED_00809 2.3e-96 J Acetyltransferase (GNAT) domain
HDFOJLED_00810 2.9e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDFOJLED_00811 6.5e-178 I Carboxylesterase family
HDFOJLED_00812 1.1e-64 arsC 1.20.4.1 P Belongs to the ArsC family
HDFOJLED_00813 4e-27
HDFOJLED_00814 6.9e-62 S Bacterial PH domain
HDFOJLED_00815 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HDFOJLED_00816 2.5e-120 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HDFOJLED_00817 4.4e-143 2.4.2.3 F Phosphorylase superfamily
HDFOJLED_00818 1.8e-144 2.4.2.3 F Phosphorylase superfamily
HDFOJLED_00819 2e-149 2.7.1.89 M Phosphotransferase enzyme family
HDFOJLED_00820 6.1e-57 S AAA domain
HDFOJLED_00821 1.2e-22 S AAA domain
HDFOJLED_00822 4.2e-32 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
HDFOJLED_00823 4.3e-21 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
HDFOJLED_00824 3e-45
HDFOJLED_00825 4.7e-91 yxaM EGP Major facilitator Superfamily
HDFOJLED_00826 8e-51 3.6.1.55 F NUDIX domain
HDFOJLED_00827 2.9e-31 S Protein of unknown function (DUF3923)
HDFOJLED_00828 3.3e-43
HDFOJLED_00829 5.3e-57
HDFOJLED_00830 4.7e-26 S MazG-like family
HDFOJLED_00831 4.9e-148 S Protein of unknown function (DUF2785)
HDFOJLED_00832 7.1e-80 K Acetyltransferase (GNAT) domain
HDFOJLED_00833 7.6e-47
HDFOJLED_00834 2.3e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HDFOJLED_00835 8.4e-47
HDFOJLED_00836 6.6e-43 glcU U sugar transport
HDFOJLED_00837 1.9e-84 glcU U sugar transport
HDFOJLED_00838 1.5e-108 S Domain of unknown function (DUF4411)
HDFOJLED_00839 8.2e-221 E IrrE N-terminal-like domain
HDFOJLED_00840 2.8e-07 yfdK S phosphatase homologous to the C-terminal domain of histone macroH2A1
HDFOJLED_00841 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HDFOJLED_00842 4.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HDFOJLED_00843 1.4e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDFOJLED_00844 1.8e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HDFOJLED_00845 1.1e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDFOJLED_00846 1.3e-165 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDFOJLED_00847 2.9e-120 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDFOJLED_00848 3.3e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDFOJLED_00849 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDFOJLED_00850 1.4e-242 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDFOJLED_00851 0.0 oatA I Acyltransferase
HDFOJLED_00852 6.8e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDFOJLED_00853 6.1e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDFOJLED_00854 6.2e-33 yrvD S Lipopolysaccharide assembly protein A domain
HDFOJLED_00855 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HDFOJLED_00856 1.5e-307 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HDFOJLED_00857 2.5e-22 S Protein of unknown function (DUF2929)
HDFOJLED_00858 0.0 dnaE 2.7.7.7 L DNA polymerase
HDFOJLED_00859 6.6e-184 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDFOJLED_00860 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HDFOJLED_00861 5.5e-169 cvfB S S1 domain
HDFOJLED_00862 4e-167 xerD D recombinase XerD
HDFOJLED_00863 4.9e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDFOJLED_00864 7.2e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDFOJLED_00865 9.2e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDFOJLED_00866 8.5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDFOJLED_00867 1.2e-115 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDFOJLED_00868 3.4e-29 yocH M Lysin motif
HDFOJLED_00869 4.5e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HDFOJLED_00870 9.1e-207 rpsA 1.17.7.4 J Ribosomal protein S1
HDFOJLED_00871 3.7e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HDFOJLED_00872 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDFOJLED_00873 1.7e-229 S Tetratricopeptide repeat protein
HDFOJLED_00874 5.2e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDFOJLED_00875 7.8e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDFOJLED_00876 5.3e-41
HDFOJLED_00877 2e-14 K Helix-turn-helix XRE-family like proteins
HDFOJLED_00878 4.2e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDFOJLED_00879 2.5e-142 K Helix-turn-helix domain
HDFOJLED_00880 1.7e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDFOJLED_00881 8.4e-218 iscS2 2.8.1.7 E Aminotransferase class V
HDFOJLED_00882 3.2e-282 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDFOJLED_00883 6.8e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDFOJLED_00884 2.7e-82 yueI S Protein of unknown function (DUF1694)
HDFOJLED_00885 8e-241 rarA L recombination factor protein RarA
HDFOJLED_00886 2.5e-35
HDFOJLED_00887 2e-77 usp6 T universal stress protein
HDFOJLED_00888 6.8e-215 rodA D Belongs to the SEDS family
HDFOJLED_00889 2.5e-33 S Protein of unknown function (DUF2969)
HDFOJLED_00890 3.8e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HDFOJLED_00891 1.9e-178 mbl D Cell shape determining protein MreB Mrl
HDFOJLED_00892 5.8e-30 ywzB S Protein of unknown function (DUF1146)
HDFOJLED_00893 2.2e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HDFOJLED_00894 1.3e-233 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDFOJLED_00895 1.2e-169 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDFOJLED_00896 2.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDFOJLED_00897 6.8e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDFOJLED_00898 2.7e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDFOJLED_00899 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDFOJLED_00900 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HDFOJLED_00901 2e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDFOJLED_00902 7e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDFOJLED_00903 1.5e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDFOJLED_00904 6.9e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDFOJLED_00905 2.2e-113 tdk 2.7.1.21 F thymidine kinase
HDFOJLED_00906 1.8e-248 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HDFOJLED_00909 4.6e-196 ampC V Beta-lactamase
HDFOJLED_00910 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HDFOJLED_00911 2.5e-247 ynbB 4.4.1.1 P aluminum resistance
HDFOJLED_00912 3.4e-89 ktrA P domain protein
HDFOJLED_00913 2.7e-178 ktrB P Potassium uptake protein
HDFOJLED_00914 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HDFOJLED_00915 1.7e-78 C Flavodoxin
HDFOJLED_00916 2e-112 3.6.1.27 I Acid phosphatase homologues
HDFOJLED_00917 2.7e-106 lacA 2.3.1.79 S Transferase hexapeptide repeat
HDFOJLED_00918 2.2e-207 pbpX1 V Beta-lactamase
HDFOJLED_00919 1.2e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HDFOJLED_00920 6.9e-93 S ECF-type riboflavin transporter, S component
HDFOJLED_00921 8.1e-232 S Putative peptidoglycan binding domain
HDFOJLED_00922 9.3e-237 mepA V MATE efflux family protein
HDFOJLED_00923 1e-256 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HDFOJLED_00924 1.9e-33
HDFOJLED_00925 3.9e-29 fic D Fic/DOC family
HDFOJLED_00926 2.2e-60
HDFOJLED_00927 3.8e-293 P ABC transporter
HDFOJLED_00928 1.7e-293 V ABC-type multidrug transport system, ATPase and permease components
HDFOJLED_00929 2.1e-68 S Putative adhesin
HDFOJLED_00930 1.3e-58 ypaA S Protein of unknown function (DUF1304)
HDFOJLED_00932 3.3e-78
HDFOJLED_00933 2.4e-56
HDFOJLED_00934 2.9e-116 S Fic/DOC family
HDFOJLED_00935 1.7e-102
HDFOJLED_00936 6.1e-208 EGP Major facilitator Superfamily
HDFOJLED_00937 5.4e-135
HDFOJLED_00938 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDFOJLED_00939 9e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDFOJLED_00940 4.2e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HDFOJLED_00941 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDFOJLED_00942 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDFOJLED_00943 9e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDFOJLED_00944 1.7e-34 yaaA S S4 domain protein YaaA
HDFOJLED_00945 3.9e-196 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDFOJLED_00946 7e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDFOJLED_00947 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HDFOJLED_00948 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDFOJLED_00949 3e-143 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDFOJLED_00950 6.2e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDFOJLED_00951 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDFOJLED_00952 4.3e-269 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDFOJLED_00953 3.2e-281 clcA P chloride
HDFOJLED_00954 7.2e-211
HDFOJLED_00955 1.2e-18
HDFOJLED_00956 8.5e-81 EGP Sugar (and other) transporter
HDFOJLED_00957 2.2e-38 EGP Sugar (and other) transporter
HDFOJLED_00958 1.6e-16 EGP Sugar (and other) transporter
HDFOJLED_00959 0.0 copA 3.6.3.54 P P-type ATPase
HDFOJLED_00960 1.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HDFOJLED_00961 1.2e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HDFOJLED_00962 2.7e-76 atkY K Penicillinase repressor
HDFOJLED_00963 2.3e-35
HDFOJLED_00964 6.7e-224 pbuG S permease
HDFOJLED_00965 4.2e-79 yheS_2 S ATPases associated with a variety of cellular activities
HDFOJLED_00966 3.4e-32 yheS_2 S ATPases associated with a variety of cellular activities
HDFOJLED_00967 2.9e-84
HDFOJLED_00968 6.1e-58
HDFOJLED_00969 5.8e-244 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDFOJLED_00970 1.6e-246 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDFOJLED_00971 7e-181 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDFOJLED_00974 9e-203 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HDFOJLED_00975 2e-191 asnA 6.3.1.1 F aspartate--ammonia ligase
HDFOJLED_00976 3.8e-106 steT_1 E amino acid
HDFOJLED_00977 1.5e-14 puuD S peptidase C26
HDFOJLED_00978 1.9e-245 yifK E Amino acid permease
HDFOJLED_00979 3.3e-216 cycA E Amino acid permease
HDFOJLED_00980 4.1e-128
HDFOJLED_00981 4.9e-119 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HDFOJLED_00982 0.0 clpE O AAA domain (Cdc48 subfamily)
HDFOJLED_00983 6e-157 S Alpha/beta hydrolase of unknown function (DUF915)
HDFOJLED_00984 6.2e-211 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDFOJLED_00985 5e-125 XK27_06785 V ABC transporter, ATP-binding protein
HDFOJLED_00986 1.7e-113 XK27_06780 V ABC transporter permease
HDFOJLED_00987 6.1e-193 XK27_06780 V ABC transporter permease
HDFOJLED_00988 1.2e-35
HDFOJLED_00989 1e-285 ytgP S Polysaccharide biosynthesis protein
HDFOJLED_00990 3.4e-148 lysA2 M Glycosyl hydrolases family 25
HDFOJLED_00991 2.1e-141 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HDFOJLED_00992 2.3e-23 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HDFOJLED_00993 2.2e-105 K Bacterial regulatory proteins, tetR family
HDFOJLED_00994 5.8e-252 V Restriction endonuclease
HDFOJLED_00995 6.9e-251 pipD E Dipeptidase
HDFOJLED_00996 2.1e-231 S LPXTG cell wall anchor motif
HDFOJLED_00997 6.1e-148 S Putative ABC-transporter type IV
HDFOJLED_00998 2.5e-98 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HDFOJLED_00999 1.7e-85 S ECF transporter, substrate-specific component
HDFOJLED_01000 2.1e-59 S Domain of unknown function (DUF4430)
HDFOJLED_01001 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HDFOJLED_01002 3.2e-176 K AI-2E family transporter
HDFOJLED_01003 6.8e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HDFOJLED_01004 1.3e-11
HDFOJLED_01005 3.2e-51
HDFOJLED_01006 9.6e-138 XK27_08845 S ABC transporter, ATP-binding protein
HDFOJLED_01007 6.4e-125 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HDFOJLED_01008 5.5e-178 ABC-SBP S ABC transporter
HDFOJLED_01009 9.2e-135 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HDFOJLED_01010 1.7e-15 S Bacteriocin helveticin-J
HDFOJLED_01011 2.5e-211 S SLAP domain
HDFOJLED_01012 1.4e-164 yvgN C Aldo keto reductase
HDFOJLED_01013 0.0 tetP J elongation factor G
HDFOJLED_01014 7.9e-154 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HDFOJLED_01015 4.3e-121 nisT V ABC transporter
HDFOJLED_01016 4.8e-57 pacL 3.6.3.8 P P-type ATPase
HDFOJLED_01017 0.0 pacL 3.6.3.8 P P-type ATPase
HDFOJLED_01018 2.1e-224 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDFOJLED_01019 2.4e-259 epsU S Polysaccharide biosynthesis protein
HDFOJLED_01020 1.7e-136 M Glycosyltransferase sugar-binding region containing DXD motif
HDFOJLED_01021 5.3e-86 ydcK S Belongs to the SprT family
HDFOJLED_01023 2e-104 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HDFOJLED_01024 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HDFOJLED_01025 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDFOJLED_01026 3e-207 camS S sex pheromone
HDFOJLED_01027 5.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDFOJLED_01028 8.4e-260 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDFOJLED_01029 2.9e-276 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDFOJLED_01030 3e-170 yegS 2.7.1.107 G Lipid kinase
HDFOJLED_01031 4.7e-115 S Protein of unknown function (DUF1211)
HDFOJLED_01032 1.1e-119 ybhL S Belongs to the BI1 family
HDFOJLED_01033 3.5e-55
HDFOJLED_01034 9.2e-248 nhaC C Na H antiporter NhaC
HDFOJLED_01035 9.8e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDFOJLED_01036 1.4e-170 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HDFOJLED_01037 1.2e-257 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HDFOJLED_01038 1.6e-28 cspA K Cold shock protein
HDFOJLED_01041 8.7e-116 L helicase activity
HDFOJLED_01042 2.8e-61
HDFOJLED_01043 2.1e-96 MA20_25245 K Acetyltransferase (GNAT) domain
HDFOJLED_01047 1.6e-242 emrY EGP Major facilitator Superfamily
HDFOJLED_01048 9.1e-92 yxdD K Bacterial regulatory proteins, tetR family
HDFOJLED_01049 2.3e-165 4.2.1.53 S Myosin-crossreactive antigen
HDFOJLED_01050 9.4e-152 4.2.1.53 S MCRA family
HDFOJLED_01051 9.9e-85 2.3.1.128 K acetyltransferase
HDFOJLED_01052 3.3e-144 G PTS system mannose/fructose/sorbose family IID component
HDFOJLED_01053 3.4e-41 G PTS system sorbose-specific iic component
HDFOJLED_01054 4e-73 G PTS system sorbose-specific iic component
HDFOJLED_01055 9.5e-78 2.7.1.191 G PTS system sorbose subfamily IIB component
HDFOJLED_01056 1.7e-29 2.7.1.191 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HDFOJLED_01057 7.3e-155 S reductase
HDFOJLED_01058 1.7e-238 pyrP F Permease
HDFOJLED_01059 7.5e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDFOJLED_01060 2.1e-258 emrY EGP Major facilitator Superfamily
HDFOJLED_01061 2.3e-168 mdtG EGP Major facilitator Superfamily
HDFOJLED_01062 5.4e-33 mdtG EGP Major facilitator Superfamily
HDFOJLED_01063 7.8e-210 pepA E M42 glutamyl aminopeptidase
HDFOJLED_01064 5.8e-310 ybiT S ABC transporter, ATP-binding protein
HDFOJLED_01065 9.9e-146
HDFOJLED_01066 4.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
HDFOJLED_01067 5.5e-147 glnH ET ABC transporter
HDFOJLED_01068 2.2e-79 K Transcriptional regulator, MarR family
HDFOJLED_01069 5e-291 XK27_09600 V ABC transporter, ATP-binding protein
HDFOJLED_01070 0.0 V ABC transporter transmembrane region
HDFOJLED_01071 2.4e-101 S ABC-type cobalt transport system, permease component
HDFOJLED_01072 3.7e-94 EGP Major facilitator superfamily
HDFOJLED_01073 4.2e-63 EGP Major facilitator superfamily
HDFOJLED_01074 2.1e-81 udk 2.7.1.48 F Zeta toxin
HDFOJLED_01075 1.9e-18 udk 2.7.1.48 F Zeta toxin
HDFOJLED_01076 2e-85 tlpA2 L Transposase IS200 like
HDFOJLED_01077 1.4e-224 L transposase, IS605 OrfB family
HDFOJLED_01078 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDFOJLED_01079 4e-150 glnH ET ABC transporter substrate-binding protein
HDFOJLED_01080 1.5e-107 gluC P ABC transporter permease
HDFOJLED_01081 2.2e-106 glnP P ABC transporter permease
HDFOJLED_01082 9.3e-113 S Protein of unknown function (DUF2974)
HDFOJLED_01083 2.8e-20 S Protein of unknown function (DUF2974)
HDFOJLED_01084 5.3e-131 K sequence-specific DNA binding
HDFOJLED_01085 4.3e-165 S SLAP domain
HDFOJLED_01086 2.7e-60 S Bacteriocin helveticin-J
HDFOJLED_01087 9.3e-234 G Bacterial extracellular solute-binding protein
HDFOJLED_01088 2.9e-161 2.7.7.12 C Domain of unknown function (DUF4931)
HDFOJLED_01089 5.9e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDFOJLED_01090 2.6e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HDFOJLED_01091 0.0 kup P Transport of potassium into the cell
HDFOJLED_01092 4.8e-176 rihB 3.2.2.1 F Nucleoside
HDFOJLED_01093 5.7e-132 gntR K UbiC transcription regulator-associated domain protein
HDFOJLED_01094 3.7e-17 ropB K Helix-turn-helix domain
HDFOJLED_01095 3.3e-62 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HDFOJLED_01096 4.5e-55 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HDFOJLED_01097 3e-153 S hydrolase
HDFOJLED_01098 9e-14
HDFOJLED_01099 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDFOJLED_01100 1.2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDFOJLED_01101 2.1e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDFOJLED_01102 4.1e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDFOJLED_01103 2.6e-247 dnaB L Replication initiation and membrane attachment
HDFOJLED_01104 4.5e-166 dnaI L Primosomal protein DnaI
HDFOJLED_01105 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDFOJLED_01106 1.5e-89
HDFOJLED_01107 4.1e-95
HDFOJLED_01108 2.9e-184 S Domain of unknown function (DUF389)
HDFOJLED_01109 9.3e-30 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HDFOJLED_01110 8.6e-156 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HDFOJLED_01111 8.9e-37 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HDFOJLED_01112 1.8e-54 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDFOJLED_01113 1.8e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HDFOJLED_01114 5.1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDFOJLED_01115 3.8e-93 yqeG S HAD phosphatase, family IIIA
HDFOJLED_01116 4.3e-211 yqeH S Ribosome biogenesis GTPase YqeH
HDFOJLED_01117 2.4e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDFOJLED_01118 2.3e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HDFOJLED_01119 6.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDFOJLED_01120 6.6e-215 ylbM S Belongs to the UPF0348 family
HDFOJLED_01121 5.1e-96 yceD S Uncharacterized ACR, COG1399
HDFOJLED_01122 1.2e-126 K response regulator
HDFOJLED_01123 4.6e-280 arlS 2.7.13.3 T Histidine kinase
HDFOJLED_01124 2.3e-290 V ABC-type multidrug transport system, ATPase and permease components
HDFOJLED_01125 2.6e-286 V ABC-type multidrug transport system, ATPase and permease components
HDFOJLED_01127 3.7e-15 L PFAM IS66 Orf2 family protein
HDFOJLED_01128 1.2e-08
HDFOJLED_01129 3.3e-14 S Phage derived protein Gp49-like (DUF891)
HDFOJLED_01130 1.5e-40 K Helix-turn-helix XRE-family like proteins
HDFOJLED_01131 5.3e-43
HDFOJLED_01132 2.8e-21 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HDFOJLED_01133 6.8e-66 L Probable transposase
HDFOJLED_01134 1e-162 L Probable transposase
HDFOJLED_01135 2.5e-14 S Fic/DOC family
HDFOJLED_01136 3.3e-83 racA K Domain of unknown function (DUF1836)
HDFOJLED_01137 2.3e-153 yitS S EDD domain protein, DegV family
HDFOJLED_01139 5.5e-20 UW LPXTG-motif cell wall anchor domain protein
HDFOJLED_01140 9e-150 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HDFOJLED_01141 4.9e-54
HDFOJLED_01142 2.5e-138 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HDFOJLED_01143 4.9e-134 mgtC S MgtC family
HDFOJLED_01144 1.9e-09 5.3.3.2 C FMN-dependent dehydrogenase
HDFOJLED_01145 1.4e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDFOJLED_01146 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDFOJLED_01147 3.6e-55 yheA S Belongs to the UPF0342 family
HDFOJLED_01148 7.7e-230 yhaO L Ser Thr phosphatase family protein
HDFOJLED_01149 0.0 L AAA domain
HDFOJLED_01150 4.5e-188 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDFOJLED_01151 1.3e-51 S PAS domain
HDFOJLED_01152 1.1e-170 whiA K May be required for sporulation
HDFOJLED_01153 2.9e-193 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HDFOJLED_01154 9e-164 rapZ S Displays ATPase and GTPase activities
HDFOJLED_01155 9.1e-82 S Short repeat of unknown function (DUF308)
HDFOJLED_01156 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDFOJLED_01157 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDFOJLED_01158 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HDFOJLED_01159 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HDFOJLED_01160 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDFOJLED_01161 4e-286 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HDFOJLED_01162 3.5e-216 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HDFOJLED_01163 6.4e-202 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HDFOJLED_01164 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HDFOJLED_01165 3.8e-15
HDFOJLED_01166 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDFOJLED_01167 4.5e-118 srtA 3.4.22.70 M sortase family
HDFOJLED_01168 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HDFOJLED_01169 1.8e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDFOJLED_01170 6.8e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HDFOJLED_01171 1.6e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HDFOJLED_01172 2.7e-253 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDFOJLED_01173 2.4e-84 3.4.21.96 S SLAP domain
HDFOJLED_01174 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HDFOJLED_01175 1.8e-156 lysR5 K LysR substrate binding domain
HDFOJLED_01176 3.2e-26 arcA 3.5.3.6 E Arginine
HDFOJLED_01177 1.6e-56 arcA 3.5.3.6 E Arginine
HDFOJLED_01178 7.1e-90 arcA 3.5.3.6 E Arginine
HDFOJLED_01179 1.1e-12 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDFOJLED_01180 1.2e-120 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDFOJLED_01181 1.4e-69 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HDFOJLED_01182 2.8e-52 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HDFOJLED_01183 8.4e-96 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HDFOJLED_01184 3.1e-212 S Sterol carrier protein domain
HDFOJLED_01185 2.5e-19
HDFOJLED_01186 5.9e-106 K LysR substrate binding domain
HDFOJLED_01187 1.3e-53
HDFOJLED_01188 4.6e-91 S VanZ like family
HDFOJLED_01189 8.9e-133 yebC K Transcriptional regulatory protein
HDFOJLED_01190 2.7e-177 comGA NU Type II IV secretion system protein
HDFOJLED_01191 7.6e-175 comGB NU type II secretion system
HDFOJLED_01192 3.7e-44 comGC U competence protein ComGC
HDFOJLED_01193 2.1e-73
HDFOJLED_01194 1e-41
HDFOJLED_01195 8.4e-82 comGF U Putative Competence protein ComGF
HDFOJLED_01196 3.9e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
HDFOJLED_01197 2e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDFOJLED_01199 2.4e-34 M Protein of unknown function (DUF3737)
HDFOJLED_01200 2.1e-32 M Protein of unknown function (DUF3737)
HDFOJLED_01201 8.9e-14 patB 4.4.1.8 E Aminotransferase, class I
HDFOJLED_01202 1.2e-154 patB 4.4.1.8 E Aminotransferase, class I
HDFOJLED_01203 1.4e-30 patB 4.4.1.8 E Aminotransferase, class I
HDFOJLED_01204 8.6e-168 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDFOJLED_01205 2.4e-60 S SdpI/YhfL protein family
HDFOJLED_01206 1.7e-128 K Transcriptional regulatory protein, C terminal
HDFOJLED_01207 5.7e-272 yclK 2.7.13.3 T Histidine kinase
HDFOJLED_01208 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDFOJLED_01209 8.3e-108 vanZ V VanZ like family
HDFOJLED_01210 2.1e-260 pgi 5.3.1.9 G Belongs to the GPI family
HDFOJLED_01211 1.2e-131 cobQ S glutamine amidotransferase
HDFOJLED_01213 5.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HDFOJLED_01214 5.2e-229 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDFOJLED_01215 3e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
HDFOJLED_01216 1.9e-175 yvdE K helix_turn _helix lactose operon repressor
HDFOJLED_01217 3e-125 ackA 2.7.2.1 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDFOJLED_01218 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HDFOJLED_01219 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HDFOJLED_01220 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HDFOJLED_01221 9.7e-118 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HDFOJLED_01222 1.4e-209 msmX P Belongs to the ABC transporter superfamily
HDFOJLED_01223 2.1e-211 malE G Bacterial extracellular solute-binding protein
HDFOJLED_01224 8.8e-251 malF P Binding-protein-dependent transport system inner membrane component
HDFOJLED_01225 4.1e-153 malG P ABC transporter permease
HDFOJLED_01226 5.2e-35 ymdB S Macro domain protein
HDFOJLED_01227 2.1e-37 L Psort location Cytoplasmic, score
HDFOJLED_01228 3.3e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDFOJLED_01229 4.2e-175 prmA J Ribosomal protein L11 methyltransferase
HDFOJLED_01230 8.5e-60
HDFOJLED_01231 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDFOJLED_01232 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDFOJLED_01233 3.1e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HDFOJLED_01234 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HDFOJLED_01235 3.4e-222 patA 2.6.1.1 E Aminotransferase
HDFOJLED_01236 3e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDFOJLED_01237 1.2e-35 S reductase
HDFOJLED_01238 1.9e-74 S reductase
HDFOJLED_01239 3.4e-86 yxeH S hydrolase
HDFOJLED_01240 7e-27 yxeH S hydrolase
HDFOJLED_01241 2.3e-10 yxeH S hydrolase
HDFOJLED_01242 3.5e-14 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDFOJLED_01243 3.4e-78 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDFOJLED_01244 3.3e-43 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDFOJLED_01245 2.2e-249 yfnA E Amino Acid
HDFOJLED_01246 4.1e-56 dedA 3.1.3.1 S SNARE associated Golgi protein
HDFOJLED_01247 3.2e-10 dedA 3.1.3.1 S SNARE associated Golgi protein
HDFOJLED_01249 8.8e-142 S ABC-2 family transporter protein
HDFOJLED_01250 8.8e-110 S ABC-2 family transporter protein
HDFOJLED_01251 5.9e-180 S ABC transporter
HDFOJLED_01252 3e-09 C WbqC-like protein family
HDFOJLED_01253 1.7e-31
HDFOJLED_01254 2.1e-39
HDFOJLED_01255 2.3e-90 3.6.1.55 L NUDIX domain
HDFOJLED_01256 1.8e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HDFOJLED_01257 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HDFOJLED_01258 2.2e-12 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDFOJLED_01259 6.1e-111 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDFOJLED_01260 2e-102 padC Q Phenolic acid decarboxylase
HDFOJLED_01261 6.1e-91 padR K Virulence activator alpha C-term
HDFOJLED_01262 1.5e-110 M ErfK YbiS YcfS YnhG
HDFOJLED_01263 6.2e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDFOJLED_01264 6.4e-243 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDFOJLED_01266 4.4e-49 pspC KT PspC domain
HDFOJLED_01267 1.6e-171 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
HDFOJLED_01268 2.4e-37 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
HDFOJLED_01269 4.2e-37 S Enterocin A Immunity
HDFOJLED_01270 1.5e-136 yxeH S hydrolase
HDFOJLED_01271 6.3e-97 S Uncharacterised protein family (UPF0236)
HDFOJLED_01272 6.2e-26 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDFOJLED_01273 9.4e-133 S Membrane protein involved in the export of O-antigen and teichoic acid
HDFOJLED_01274 3.3e-66 M Glycosyltransferase like family 2
HDFOJLED_01275 4e-151 S Core-2/I-Branching enzyme
HDFOJLED_01276 4.3e-211 glf 5.4.99.9 M UDP-galactopyranose mutase
HDFOJLED_01277 2.8e-105 lgtD S glycosyl transferase family 2
HDFOJLED_01278 1.9e-185
HDFOJLED_01279 7.7e-146 M Domain of unknown function (DUF4422)
HDFOJLED_01280 4.5e-155 GT4 M Glycosyl transferases group 1
HDFOJLED_01281 1.1e-28 GT2,GT4 S Hydrolase
HDFOJLED_01282 1.6e-65 GT2,GT4
HDFOJLED_01283 2.4e-125 cps1D M Domain of unknown function (DUF4422)
HDFOJLED_01284 2.7e-96 rfbP 2.7.8.6 M Bacterial sugar transferase
HDFOJLED_01285 5.7e-146 ywqE 3.1.3.48 GM PHP domain protein
HDFOJLED_01286 1.1e-118 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HDFOJLED_01287 2.1e-144 epsB M biosynthesis protein
HDFOJLED_01288 1.6e-178 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDFOJLED_01289 1.1e-199 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDFOJLED_01290 1.4e-87 S SLAP domain
HDFOJLED_01291 5.1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDFOJLED_01292 5.5e-148 GK ROK family
HDFOJLED_01293 5.5e-43
HDFOJLED_01294 4.7e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDFOJLED_01295 3.6e-67 S Domain of unknown function (DUF1934)
HDFOJLED_01296 1.5e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDFOJLED_01297 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDFOJLED_01298 8.1e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDFOJLED_01299 3.7e-33 S Haloacid dehalogenase-like hydrolase
HDFOJLED_01300 4.4e-49 S Haloacid dehalogenase-like hydrolase
HDFOJLED_01301 1.4e-283 pipD E Dipeptidase
HDFOJLED_01302 1.4e-158 msmR K AraC-like ligand binding domain
HDFOJLED_01303 2.2e-219 pbuX F xanthine permease
HDFOJLED_01304 1.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDFOJLED_01305 3e-53 K DNA-binding helix-turn-helix protein
HDFOJLED_01306 3.7e-17 K Helix-turn-helix
HDFOJLED_01307 1e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HDFOJLED_01308 5.6e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDFOJLED_01309 0.0 dnaK O Heat shock 70 kDa protein
HDFOJLED_01310 8.2e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDFOJLED_01311 4.5e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDFOJLED_01312 2.3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HDFOJLED_01313 2.8e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDFOJLED_01314 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDFOJLED_01315 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDFOJLED_01316 1e-45 rplGA J ribosomal protein
HDFOJLED_01317 3e-47 ylxR K Protein of unknown function (DUF448)
HDFOJLED_01318 4.6e-195 nusA K Participates in both transcription termination and antitermination
HDFOJLED_01319 5.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HDFOJLED_01320 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDFOJLED_01321 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDFOJLED_01322 4.4e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HDFOJLED_01323 1.6e-146 cdsA 2.7.7.41 I Belongs to the CDS family
HDFOJLED_01324 7.8e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDFOJLED_01325 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDFOJLED_01326 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HDFOJLED_01327 7e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDFOJLED_01328 1.2e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
HDFOJLED_01329 1.7e-198 yabB 2.1.1.223 L Methyltransferase small domain
HDFOJLED_01330 5.1e-113 plsC 2.3.1.51 I Acyltransferase
HDFOJLED_01331 3.2e-225 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HDFOJLED_01332 0.0 pepO 3.4.24.71 O Peptidase family M13
HDFOJLED_01333 1.9e-19 mdlB V ABC transporter
HDFOJLED_01334 1.2e-270 mdlB V ABC transporter
HDFOJLED_01335 1e-296 mdlA V ABC transporter
HDFOJLED_01336 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
HDFOJLED_01337 4.3e-37 ynzC S UPF0291 protein
HDFOJLED_01338 1.5e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDFOJLED_01339 2.1e-148 E GDSL-like Lipase/Acylhydrolase family
HDFOJLED_01340 9.2e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HDFOJLED_01341 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDFOJLED_01342 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HDFOJLED_01343 4.1e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDFOJLED_01344 4.5e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HDFOJLED_01345 1.9e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDFOJLED_01346 3.2e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDFOJLED_01347 1.7e-193 L Transposase and inactivated derivatives, IS30 family
HDFOJLED_01348 3.5e-258 yfnA E amino acid
HDFOJLED_01349 1.8e-44
HDFOJLED_01350 1.7e-289 pipD E Dipeptidase
HDFOJLED_01351 4.9e-166 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDFOJLED_01352 0.0 smc D Required for chromosome condensation and partitioning
HDFOJLED_01353 1.3e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDFOJLED_01354 0.0 oppA E ABC transporter substrate-binding protein
HDFOJLED_01355 0.0 oppA E ABC transporter substrate-binding protein
HDFOJLED_01356 8.4e-144 oppC P Binding-protein-dependent transport system inner membrane component
HDFOJLED_01357 6.6e-176 oppB P ABC transporter permease
HDFOJLED_01358 1.2e-180 oppF P Belongs to the ABC transporter superfamily
HDFOJLED_01359 1.7e-193 oppD P Belongs to the ABC transporter superfamily
HDFOJLED_01360 9.8e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDFOJLED_01361 2.9e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDFOJLED_01362 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDFOJLED_01363 2.2e-304 yloV S DAK2 domain fusion protein YloV
HDFOJLED_01364 6.8e-57 asp S Asp23 family, cell envelope-related function
HDFOJLED_01365 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HDFOJLED_01366 5.7e-49
HDFOJLED_01367 9.2e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDFOJLED_01368 1.6e-168 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HDFOJLED_01369 2.8e-26 S Phage derived protein Gp49-like (DUF891)
HDFOJLED_01370 9e-38 K Helix-turn-helix domain
HDFOJLED_01371 1.5e-169 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HDFOJLED_01372 0.0 S membrane
HDFOJLED_01373 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HDFOJLED_01374 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDFOJLED_01375 1.7e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDFOJLED_01376 5.4e-116 gluP 3.4.21.105 S Rhomboid family
HDFOJLED_01377 5.6e-33 yqgQ S Bacterial protein of unknown function (DUF910)
HDFOJLED_01378 4.5e-70 yqhL P Rhodanese-like protein
HDFOJLED_01379 3.6e-171 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDFOJLED_01380 2.6e-30 ynbB 4.4.1.1 P aluminum resistance
HDFOJLED_01381 1.9e-169 ynbB 4.4.1.1 P aluminum resistance
HDFOJLED_01382 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
HDFOJLED_01383 1.8e-135
HDFOJLED_01384 1.4e-164
HDFOJLED_01385 2.7e-148
HDFOJLED_01387 8.2e-200 M Glycosyl hydrolases family 25
HDFOJLED_01388 0.0 S Predicted membrane protein (DUF2207)
HDFOJLED_01389 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HDFOJLED_01390 1e-127 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HDFOJLED_01391 1.5e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HDFOJLED_01392 4.1e-256 S Uncharacterized protein conserved in bacteria (DUF2325)
HDFOJLED_01393 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HDFOJLED_01394 1e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HDFOJLED_01395 7.5e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HDFOJLED_01396 9.2e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDFOJLED_01397 5.3e-69 yqhY S Asp23 family, cell envelope-related function
HDFOJLED_01398 1.4e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDFOJLED_01399 2e-152 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDFOJLED_01400 3.4e-194 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDFOJLED_01401 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDFOJLED_01402 2.1e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDFOJLED_01403 6.8e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HDFOJLED_01404 1.8e-306 recN L May be involved in recombinational repair of damaged DNA
HDFOJLED_01405 3.8e-78 6.3.3.2 S ASCH
HDFOJLED_01406 1.3e-51
HDFOJLED_01407 1.1e-275 E Amino acid permease
HDFOJLED_01408 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HDFOJLED_01409 9.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDFOJLED_01410 1.7e-94 pbpX2 V Beta-lactamase
HDFOJLED_01411 4.8e-84 3.2.2.20 K acetyltransferase
HDFOJLED_01412 8e-96
HDFOJLED_01413 1.9e-46
HDFOJLED_01414 6.9e-41
HDFOJLED_01415 6.9e-44 glvR K Helix-turn-helix domain, rpiR family
HDFOJLED_01416 6e-188 ansA 3.5.1.1 EJ L-asparaginase, type I
HDFOJLED_01417 3.2e-15
HDFOJLED_01418 3.1e-124
HDFOJLED_01419 2.7e-238 S response to antibiotic
HDFOJLED_01420 2.7e-132 cysA V ABC transporter, ATP-binding protein
HDFOJLED_01421 0.0 V FtsX-like permease family
HDFOJLED_01422 3.4e-50 asdA 4.1.1.12 E Aminotransferase class I and II
HDFOJLED_01423 3e-10
HDFOJLED_01424 2e-161 L Belongs to the 'phage' integrase family
HDFOJLED_01425 4.8e-17
HDFOJLED_01426 3.5e-138 repB EP Plasmid replication protein
HDFOJLED_01427 7.3e-31
HDFOJLED_01428 8.2e-167 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HDFOJLED_01429 3.4e-33
HDFOJLED_01430 3.7e-18
HDFOJLED_01431 7.2e-81
HDFOJLED_01432 8.1e-196 L COG2826 Transposase and inactivated derivatives, IS30 family
HDFOJLED_01433 4.2e-300 3.1.21.5 L Type III restriction enzyme, res subunit
HDFOJLED_01434 6.4e-208 2.1.1.72 L PFAM DNA methylase N-4 N-6 domain protein
HDFOJLED_01436 5.4e-119 yhiD S MgtC family
HDFOJLED_01437 2.8e-240 I Protein of unknown function (DUF2974)
HDFOJLED_01438 8.1e-36
HDFOJLED_01440 2.1e-117 S CAAX protease self-immunity
HDFOJLED_01441 1.9e-195 S DUF218 domain
HDFOJLED_01442 0.0 macB_3 V ABC transporter, ATP-binding protein
HDFOJLED_01443 2.1e-95 S ECF transporter, substrate-specific component
HDFOJLED_01444 2.2e-159 yeaE S Aldo/keto reductase family
HDFOJLED_01445 1.5e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDFOJLED_01446 6.1e-101 ybbH_2 K rpiR family
HDFOJLED_01447 8.5e-145 S Bacterial protein of unknown function (DUF871)
HDFOJLED_01448 4.3e-190 yfeW 3.4.16.4 V Beta-lactamase
HDFOJLED_01449 4.3e-121 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HDFOJLED_01450 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDFOJLED_01452 2.7e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HDFOJLED_01453 1.8e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HDFOJLED_01454 8.2e-166
HDFOJLED_01457 1.5e-288 lsa S ABC transporter
HDFOJLED_01458 1.5e-17
HDFOJLED_01459 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDFOJLED_01460 1.9e-74 S Protein of unknown function (DUF3021)
HDFOJLED_01461 6.6e-75 K LytTr DNA-binding domain
HDFOJLED_01462 2.1e-103 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
HDFOJLED_01465 0.0 uvrA3 L excinuclease ABC, A subunit
HDFOJLED_01466 8.2e-66 yyaR K Acetyltransferase (GNAT) domain
HDFOJLED_01467 2.3e-11 mta K helix_turn_helix, mercury resistance
HDFOJLED_01468 1.4e-37 mta K helix_turn_helix, mercury resistance
HDFOJLED_01469 3.6e-15 mta K helix_turn_helix, mercury resistance
HDFOJLED_01470 5.3e-07 S ParE toxin of type II toxin-antitoxin system, parDE
HDFOJLED_01472 1.6e-60 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HDFOJLED_01473 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HDFOJLED_01474 1.5e-51
HDFOJLED_01475 4.6e-206 G Major Facilitator Superfamily
HDFOJLED_01476 4.3e-49
HDFOJLED_01477 4.2e-97 S Cysteine-rich secretory protein family
HDFOJLED_01478 9.7e-46
HDFOJLED_01479 3.3e-14 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HDFOJLED_01480 4.2e-75 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HDFOJLED_01481 1.7e-149 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HDFOJLED_01482 7.4e-52 S Iron-sulfur cluster assembly protein
HDFOJLED_01483 1.7e-162 cjaA ET ABC transporter substrate-binding protein
HDFOJLED_01484 8.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDFOJLED_01485 4.8e-117 P ABC transporter permease
HDFOJLED_01486 1.7e-114 papP P ABC transporter, permease protein
HDFOJLED_01487 8.3e-32
HDFOJLED_01488 2.1e-21
HDFOJLED_01489 0.0 oppA E ABC transporter substrate-binding protein
HDFOJLED_01491 5.2e-98 S SLAP domain
HDFOJLED_01492 2.5e-48 S SLAP domain
HDFOJLED_01493 3.4e-21 XK27_01125 L IS66 Orf2 like protein
HDFOJLED_01494 1.6e-10
HDFOJLED_01495 2.3e-205 G Major Facilitator Superfamily
HDFOJLED_01497 2.6e-146 D CobQ CobB MinD ParA nucleotide binding domain protein
HDFOJLED_01498 5.3e-232 cps4J S Polysaccharide biosynthesis protein
HDFOJLED_01499 3.1e-184 2.1.1.21, 6.3.5.4 E Asparagine synthase
HDFOJLED_01500 1.8e-74 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase-like
HDFOJLED_01501 1.1e-231 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDFOJLED_01502 3.5e-134 M Glycosyltransferase sugar-binding region containing DXD motif
HDFOJLED_01503 4.7e-189 S EpsG family
HDFOJLED_01504 1.4e-152 epsE GT2 M Glycosyltransferase like family 2
HDFOJLED_01505 4.3e-206 M Glycosyl transferases group 1
HDFOJLED_01506 3.9e-119 rfbP M Bacterial sugar transferase
HDFOJLED_01507 1.1e-20 ywqE 3.1.3.48 GM PHP domain protein
HDFOJLED_01508 6.3e-92 epsB M biosynthesis protein
HDFOJLED_01510 1.6e-33 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDFOJLED_01511 1.3e-39 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDFOJLED_01512 4.4e-158 psaA P Belongs to the bacterial solute-binding protein 9 family
HDFOJLED_01513 1.6e-117 fhuC P ABC transporter
HDFOJLED_01514 2.6e-130 znuB U ABC 3 transport family
HDFOJLED_01515 9.9e-234 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDFOJLED_01516 3e-248 ade 3.5.4.2 F Adenine deaminase C-terminal domain
HDFOJLED_01517 2.6e-141 potD2 P ABC transporter
HDFOJLED_01518 5.7e-133 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDFOJLED_01519 2.3e-105 potC3 E Binding-protein-dependent transport system inner membrane component
HDFOJLED_01520 1.6e-101 potB E Binding-protein-dependent transport system inner membrane component
HDFOJLED_01521 5.3e-35 lctP C L-lactate permease
HDFOJLED_01522 2.1e-90 lctP C L-lactate permease
HDFOJLED_01523 3.6e-52 lctP C L-lactate permease
HDFOJLED_01524 2.1e-42 S Enterocin A Immunity
HDFOJLED_01525 2.1e-28 bioY S BioY family
HDFOJLED_01526 1.1e-189 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDFOJLED_01527 1.9e-133 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HDFOJLED_01528 4.1e-144 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HDFOJLED_01529 6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDFOJLED_01530 1.5e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HDFOJLED_01531 1.7e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HDFOJLED_01532 3.7e-79 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDFOJLED_01533 1.3e-229 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDFOJLED_01534 1.2e-126 IQ reductase
HDFOJLED_01535 3.7e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HDFOJLED_01536 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDFOJLED_01537 1e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDFOJLED_01538 1.1e-78 marR K Transcriptional regulator
HDFOJLED_01539 3.8e-78 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDFOJLED_01540 5.1e-147 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HDFOJLED_01541 7e-13 ytgB S Transglycosylase associated protein
HDFOJLED_01542 2.1e-177 lysC 2.7.2.4 E Belongs to the aspartokinase family
HDFOJLED_01543 7.1e-246 thrC 4.2.3.1 E Threonine synthase
HDFOJLED_01544 1.3e-122 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HDFOJLED_01545 8.6e-110 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDFOJLED_01546 1.5e-107
HDFOJLED_01547 1.4e-161 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDFOJLED_01548 1.3e-39 S Peptidase family M23
HDFOJLED_01549 6.8e-153 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HDFOJLED_01550 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HDFOJLED_01551 3.2e-69 yqeY S YqeY-like protein
HDFOJLED_01552 8.9e-173 phoH T phosphate starvation-inducible protein PhoH
HDFOJLED_01553 3.2e-92 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDFOJLED_01554 1.8e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDFOJLED_01555 1e-136 recO L Involved in DNA repair and RecF pathway recombination
HDFOJLED_01556 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HDFOJLED_01557 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HDFOJLED_01558 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDFOJLED_01559 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDFOJLED_01560 6.8e-124 S Peptidase family M23
HDFOJLED_01561 3.6e-68 mutT 3.6.1.55 F NUDIX domain
HDFOJLED_01562 2.4e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
HDFOJLED_01563 1e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDFOJLED_01564 1.4e-242 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HDFOJLED_01565 3.9e-60 yvoA_1 K Transcriptional regulator, GntR family
HDFOJLED_01566 2.8e-123 skfE V ATPases associated with a variety of cellular activities
HDFOJLED_01567 1.6e-146
HDFOJLED_01568 1.1e-147
HDFOJLED_01569 4.8e-129
HDFOJLED_01570 4.9e-10 rarA L recombination factor protein RarA
HDFOJLED_01571 9.8e-115 rarA L recombination factor protein RarA
HDFOJLED_01572 7.8e-28
HDFOJLED_01573 3e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HDFOJLED_01574 2.7e-140
HDFOJLED_01575 1.8e-176
HDFOJLED_01576 2.8e-260 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HDFOJLED_01577 4.8e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDFOJLED_01578 4.2e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HDFOJLED_01579 2.2e-179 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HDFOJLED_01580 1.8e-167 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HDFOJLED_01581 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HDFOJLED_01582 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HDFOJLED_01583 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HDFOJLED_01584 1.1e-89 ypmB S Protein conserved in bacteria
HDFOJLED_01585 1.2e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HDFOJLED_01586 7.4e-115 dnaD L DnaD domain protein
HDFOJLED_01587 5.1e-113 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDFOJLED_01588 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HDFOJLED_01589 3.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDFOJLED_01590 8.6e-107 ypsA S Belongs to the UPF0398 family
HDFOJLED_01591 8e-70 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDFOJLED_01592 2.9e-215 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HDFOJLED_01593 4.5e-200 cpdA S Calcineurin-like phosphoesterase
HDFOJLED_01594 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HDFOJLED_01595 9.5e-80 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDFOJLED_01596 3.2e-156 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDFOJLED_01597 2.3e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HDFOJLED_01598 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HDFOJLED_01599 3.8e-96 mreD
HDFOJLED_01600 1.5e-147 mreC M Involved in formation and maintenance of cell shape
HDFOJLED_01601 4.2e-173 mreB D cell shape determining protein MreB
HDFOJLED_01602 2.1e-114 radC L DNA repair protein
HDFOJLED_01603 5.7e-126 S Haloacid dehalogenase-like hydrolase
HDFOJLED_01604 3e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDFOJLED_01605 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDFOJLED_01606 1.4e-96
HDFOJLED_01607 9.5e-92 S Bacterial membrane protein, YfhO
HDFOJLED_01608 8.7e-120 S Bacterial membrane protein, YfhO
HDFOJLED_01609 1.1e-12 S Bacterial membrane protein, YfhO
HDFOJLED_01610 8.9e-170 yfdH GT2 M Glycosyltransferase like family 2
HDFOJLED_01611 2.4e-66 2.4.1.83 GT2 S GtrA-like protein
HDFOJLED_01612 9.4e-211 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HDFOJLED_01613 6.7e-23
HDFOJLED_01614 4.4e-30 L Transposase
HDFOJLED_01615 2.3e-10 L Transposase
HDFOJLED_01616 3.9e-139 L Transposase
HDFOJLED_01617 7.7e-98 L Integrase
HDFOJLED_01618 4.3e-127 L Transposase and inactivated derivatives, IS30 family
HDFOJLED_01619 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
HDFOJLED_01620 3.6e-160 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDFOJLED_01621 1.1e-25 higB-2 S RelE toxin of RelE / RelB toxin-antitoxin system
HDFOJLED_01622 5.8e-22 K Helix-turn-helix XRE-family like proteins
HDFOJLED_01623 6.9e-16
HDFOJLED_01624 6.1e-226 S response to antibiotic
HDFOJLED_01625 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
HDFOJLED_01626 1.1e-275 hsdM 2.1.1.72 V type I restriction-modification system
HDFOJLED_01627 6e-149 3.1.21.3 V Type I restriction modification DNA specificity domain
HDFOJLED_01628 5.6e-72 S Psort location Cytoplasmic, score
HDFOJLED_01629 2.5e-135 mrr L restriction endonuclease
HDFOJLED_01631 1.4e-215 S SLAP domain
HDFOJLED_01633 3.6e-168 psaA P Belongs to the bacterial solute-binding protein 9 family
HDFOJLED_01636 2.5e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDFOJLED_01637 1.4e-262 qacA EGP Major facilitator Superfamily
HDFOJLED_01638 5.5e-146 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDFOJLED_01639 7.3e-118 3.6.1.27 I Acid phosphatase homologues
HDFOJLED_01640 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDFOJLED_01641 5.4e-295 ytgP S Polysaccharide biosynthesis protein
HDFOJLED_01642 2.2e-182 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HDFOJLED_01643 3e-91 dhaL 2.7.1.121 S Dak2
HDFOJLED_01644 1.3e-55 dhaM 2.7.1.121 S PTS system fructose IIA component
HDFOJLED_01646 9.2e-175 V ABC transporter transmembrane region
HDFOJLED_01647 1e-31 KLT serine threonine protein kinase
HDFOJLED_01648 3.7e-48 L An automated process has identified a potential problem with this gene model
HDFOJLED_01651 9.4e-112 S SLAP domain
HDFOJLED_01652 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HDFOJLED_01653 1.1e-67 rplI J Binds to the 23S rRNA
HDFOJLED_01654 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HDFOJLED_01655 6e-166 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HDFOJLED_01656 1.4e-175 degV S DegV family
HDFOJLED_01657 1.4e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HDFOJLED_01658 2.8e-25 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDFOJLED_01659 1.7e-29 frnE Q DSBA-like thioredoxin domain
HDFOJLED_01660 2.3e-37 frnE Q DSBA-like thioredoxin domain
HDFOJLED_01661 7.7e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDFOJLED_01662 7.2e-118 M1-798 K Rhodanese Homology Domain
HDFOJLED_01663 5.2e-36 CO Thioredoxin
HDFOJLED_01664 2.1e-20
HDFOJLED_01665 1.7e-22 UW LPXTG-motif cell wall anchor domain protein
HDFOJLED_01666 1.7e-15 infB UW LPXTG-motif cell wall anchor domain protein
HDFOJLED_01667 5.8e-72 infB UW LPXTG-motif cell wall anchor domain protein
HDFOJLED_01668 3.2e-64 O Belongs to the peptidase S8 family
HDFOJLED_01669 6.7e-93 O Belongs to the peptidase S8 family
HDFOJLED_01670 2.4e-187 O Belongs to the peptidase S8 family
HDFOJLED_01671 1.1e-10
HDFOJLED_01673 6.2e-138
HDFOJLED_01674 8.4e-77 M1-431 S Protein of unknown function (DUF1706)
HDFOJLED_01675 2.1e-71 yeaL S Protein of unknown function (DUF441)
HDFOJLED_01676 1e-09
HDFOJLED_01677 8e-146 cbiQ P cobalt transport
HDFOJLED_01678 0.0 ykoD P ABC transporter, ATP-binding protein
HDFOJLED_01679 1.4e-93 S UPF0397 protein
HDFOJLED_01680 2.2e-66 S Domain of unknown function DUF1828
HDFOJLED_01681 9.3e-16
HDFOJLED_01682 2.7e-51
HDFOJLED_01683 1.4e-173 citR K Putative sugar-binding domain
HDFOJLED_01684 3.1e-248 yjjP S Putative threonine/serine exporter
HDFOJLED_01685 2.6e-19 yxkA S Phosphatidylethanolamine-binding protein
HDFOJLED_01686 1.1e-70 yxkA S Phosphatidylethanolamine-binding protein
HDFOJLED_01687 6.4e-46
HDFOJLED_01688 3.3e-56
HDFOJLED_01689 3.4e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDFOJLED_01690 2.6e-67 yniA G Phosphotransferase enzyme family
HDFOJLED_01691 4.1e-92 yniA G Phosphotransferase enzyme family
HDFOJLED_01692 9.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
HDFOJLED_01693 2.6e-261 E amino acid
HDFOJLED_01694 0.0 L Helicase C-terminal domain protein
HDFOJLED_01695 4.3e-194 pbpX1 V Beta-lactamase
HDFOJLED_01696 3e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HDFOJLED_01697 1.3e-90
HDFOJLED_01700 9.4e-195 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HDFOJLED_01701 1.8e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDFOJLED_01702 1.5e-272 yjeM E Amino Acid
HDFOJLED_01703 3.9e-39
HDFOJLED_01704 1.4e-59
HDFOJLED_01705 7.1e-88
HDFOJLED_01706 9.6e-15
HDFOJLED_01707 5.1e-81
HDFOJLED_01708 2.3e-125 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
HDFOJLED_01709 3.5e-70 O OsmC-like protein
HDFOJLED_01710 2.1e-208 EGP Major facilitator Superfamily
HDFOJLED_01711 2.8e-198 sptS 2.7.13.3 T Histidine kinase
HDFOJLED_01712 5.5e-81 K response regulator
HDFOJLED_01713 2.5e-121 S Protein of unknown function (DUF975)
HDFOJLED_01714 9.6e-16
HDFOJLED_01715 1.8e-32
HDFOJLED_01716 1.7e-29
HDFOJLED_01717 7.1e-119 S CAAX protease self-immunity
HDFOJLED_01718 2e-10
HDFOJLED_01720 1.6e-174 pbpX2 V Beta-lactamase
HDFOJLED_01721 1.3e-240 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDFOJLED_01722 2.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFOJLED_01723 3e-237 dltB M MBOAT, membrane-bound O-acyltransferase family
HDFOJLED_01724 5.1e-292 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDFOJLED_01725 5.2e-19 S D-Ala-teichoic acid biosynthesis protein
HDFOJLED_01726 3.8e-50
HDFOJLED_01727 2.7e-213 ywhK S Membrane
HDFOJLED_01728 2.4e-23 ykuL S IMP dehydrogenase activity
HDFOJLED_01729 3e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HDFOJLED_01730 9.8e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDFOJLED_01731 2.2e-179 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDFOJLED_01732 8.4e-23
HDFOJLED_01733 3.3e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDFOJLED_01734 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDFOJLED_01735 9.4e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDFOJLED_01736 5.9e-134 comFC S Competence protein
HDFOJLED_01737 2.3e-245 comFA L Helicase C-terminal domain protein
HDFOJLED_01738 6.2e-117 yvyE 3.4.13.9 S YigZ family
HDFOJLED_01739 2.4e-209 tagO 2.7.8.33, 2.7.8.35 M transferase
HDFOJLED_01740 4.7e-219 rny S Endoribonuclease that initiates mRNA decay
HDFOJLED_01741 3.6e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDFOJLED_01742 1.9e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDFOJLED_01743 3.6e-133 ymfM S Helix-turn-helix domain
HDFOJLED_01744 5.2e-133 IQ Enoyl-(Acyl carrier protein) reductase
HDFOJLED_01745 1.3e-235 S Peptidase M16
HDFOJLED_01746 8.7e-226 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HDFOJLED_01747 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HDFOJLED_01748 1.4e-68 WQ51_03320 S Protein of unknown function (DUF1149)
HDFOJLED_01749 1.6e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDFOJLED_01750 2.4e-212 yubA S AI-2E family transporter
HDFOJLED_01751 2.4e-65 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HDFOJLED_01752 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HDFOJLED_01753 5.7e-202 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HDFOJLED_01754 3.7e-37 S SNARE associated Golgi protein
HDFOJLED_01755 1.3e-29 S SNARE associated Golgi protein
HDFOJLED_01756 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HDFOJLED_01757 5e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDFOJLED_01758 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDFOJLED_01759 2.3e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
HDFOJLED_01760 1.1e-112 yjbK S CYTH
HDFOJLED_01761 2.8e-111 yjbH Q Thioredoxin
HDFOJLED_01762 1.5e-158 coiA 3.6.4.12 S Competence protein
HDFOJLED_01763 7.6e-132 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HDFOJLED_01764 3e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDFOJLED_01765 9.3e-306 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDFOJLED_01766 8.5e-41 ptsH G phosphocarrier protein HPR
HDFOJLED_01767 2.4e-26
HDFOJLED_01768 0.0 clpE O Belongs to the ClpA ClpB family
HDFOJLED_01769 3.9e-44 XK27_09445 S Domain of unknown function (DUF1827)
HDFOJLED_01770 3.2e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDFOJLED_01771 1.3e-159 hlyX S Transporter associated domain
HDFOJLED_01772 1.3e-73
HDFOJLED_01773 1.9e-86
HDFOJLED_01774 9.6e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
HDFOJLED_01775 3.3e-261 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDFOJLED_01776 2.8e-98 D Alpha beta
HDFOJLED_01780 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDFOJLED_01781 6.3e-32 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HDFOJLED_01782 5.4e-248 treB G phosphotransferase system
HDFOJLED_01783 1.4e-48 treB G phosphotransferase system
HDFOJLED_01784 1.2e-22 treB G phosphotransferase system
HDFOJLED_01785 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HDFOJLED_01786 5e-128 treR K UTRA
HDFOJLED_01787 1.8e-07
HDFOJLED_01788 7.5e-58 S Putative transposase
HDFOJLED_01789 2.6e-85 S Putative transposase
HDFOJLED_01791 5e-19 L Transposase
HDFOJLED_01792 2.9e-08
HDFOJLED_01793 3.6e-299 S SLAP domain
HDFOJLED_01795 2.4e-30
HDFOJLED_01797 3e-26
HDFOJLED_01798 1.9e-115 G Peptidase_C39 like family
HDFOJLED_01799 4.6e-54 M NlpC/P60 family
HDFOJLED_01800 8.3e-27 M NlpC/P60 family
HDFOJLED_01801 9.1e-22 M NlpC/P60 family
HDFOJLED_01802 3.2e-22 M NlpC/P60 family
HDFOJLED_01803 1.7e-21 2.1.1.113, 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HDFOJLED_01804 2.6e-58 2.1.1.113, 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HDFOJLED_01805 6.2e-22
HDFOJLED_01806 2.3e-42 lacZ 3.2.1.23 G -beta-galactosidase
HDFOJLED_01807 1.3e-160 lacZ 3.2.1.23 G -beta-galactosidase
HDFOJLED_01808 0.0 lacS G Transporter
HDFOJLED_01809 1.5e-142 lacS G Transporter
HDFOJLED_01810 1.2e-47 lacS G Transporter
HDFOJLED_01811 4.6e-24 lacS G Transporter
HDFOJLED_01812 1.3e-187 lacR K Transcriptional regulator
HDFOJLED_01813 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HDFOJLED_01814 1.7e-187 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HDFOJLED_01815 1.2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDFOJLED_01816 1.9e-276 V ABC transporter transmembrane region
HDFOJLED_01817 9.3e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HDFOJLED_01818 2.5e-186 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HDFOJLED_01819 3e-95 F Nucleoside 2-deoxyribosyltransferase
HDFOJLED_01820 2.7e-69 S Peptidase propeptide and YPEB domain
HDFOJLED_01821 1.7e-85 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HDFOJLED_01822 1.4e-67 yybA 2.3.1.57 K Transcriptional regulator
HDFOJLED_01823 7.8e-14 S Peptidase propeptide and YPEB domain
HDFOJLED_01824 1.4e-66 S Peptidase propeptide and YPEB domain
HDFOJLED_01825 3.1e-245 G Bacterial extracellular solute-binding protein
HDFOJLED_01826 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDFOJLED_01827 3.9e-170 coaA 2.7.1.33 F Pantothenic acid kinase
HDFOJLED_01828 1.1e-103 E GDSL-like Lipase/Acylhydrolase
HDFOJLED_01829 7.6e-126 thiN 2.7.6.2 H thiamine pyrophosphokinase
HDFOJLED_01830 9.4e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HDFOJLED_01831 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDFOJLED_01832 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HDFOJLED_01833 9.2e-147 stp 3.1.3.16 T phosphatase
HDFOJLED_01834 4.1e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDFOJLED_01835 3e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDFOJLED_01836 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDFOJLED_01837 9.4e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HDFOJLED_01838 1.2e-109 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HDFOJLED_01840 6.5e-81 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDFOJLED_01841 2.9e-21
HDFOJLED_01842 1.5e-47
HDFOJLED_01843 3.4e-59
HDFOJLED_01844 4.4e-221 dnaI L DNA-dependent DNA replication
HDFOJLED_01845 3.1e-14 dnaI L DNA-dependent DNA replication
HDFOJLED_01849 3.2e-50 S Bacteriophage abortive infection AbiH
HDFOJLED_01850 9.3e-201 S Phage minor structural protein
HDFOJLED_01852 1.8e-10 S Domain of unknown function (DUF2479)
HDFOJLED_01854 3.2e-28
HDFOJLED_01857 1.1e-15
HDFOJLED_01859 1.2e-36 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HDFOJLED_01860 1e-114 M hydrolase, family 25
HDFOJLED_01862 1.1e-13
HDFOJLED_01863 0.0 FbpA K Fibronectin-binding protein
HDFOJLED_01864 2.8e-11
HDFOJLED_01865 3e-39
HDFOJLED_01866 1.8e-159 degV S EDD domain protein, DegV family
HDFOJLED_01867 7.6e-205 xerS L Belongs to the 'phage' integrase family
HDFOJLED_01868 5.3e-67
HDFOJLED_01869 5.9e-88 adk 2.7.4.3 F topology modulation protein
HDFOJLED_01870 1.2e-109 XK27_00160 S Domain of unknown function (DUF5052)
HDFOJLED_01871 1.3e-52
HDFOJLED_01872 8.2e-28 M Glycosyl hydrolases family 25
HDFOJLED_01873 3.4e-92 M Glycosyl hydrolases family 25
HDFOJLED_01874 3.3e-24 lysA2 M Glycosyl hydrolases family 25
HDFOJLED_01875 3.5e-36 S Transglycosylase associated protein
HDFOJLED_01876 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HDFOJLED_01877 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDFOJLED_01878 2.3e-29 secG U Preprotein translocase
HDFOJLED_01879 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDFOJLED_01880 3.3e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDFOJLED_01881 4.2e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
HDFOJLED_01882 8.1e-221 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HDFOJLED_01889 3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HDFOJLED_01890 7e-220 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HDFOJLED_01891 3.3e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HDFOJLED_01892 4.3e-22 IQ reductase
HDFOJLED_01893 4.7e-193 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDFOJLED_01894 1.2e-73 nrdI F Probably involved in ribonucleotide reductase function
HDFOJLED_01895 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDFOJLED_01896 7.3e-40 S Enterocin A Immunity
HDFOJLED_01897 4.6e-118 ropB K Transcriptional regulator
HDFOJLED_01898 1.9e-118 scrR K Transcriptional regulator, LacI family
HDFOJLED_01899 2.5e-122 liaI S membrane
HDFOJLED_01900 9.6e-77 XK27_02470 K LytTr DNA-binding domain
HDFOJLED_01901 5.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDFOJLED_01902 0.0 uup S ABC transporter, ATP-binding protein
HDFOJLED_01903 1.4e-12 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HDFOJLED_01904 1e-146 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HDFOJLED_01905 1.9e-56 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HDFOJLED_01906 8.2e-114 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HDFOJLED_01907 9.9e-80 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HDFOJLED_01908 3.7e-111 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HDFOJLED_01909 4.1e-28 S Toxin ToxN, type III toxin-antitoxin system
HDFOJLED_01910 2e-129 K UTRA
HDFOJLED_01911 5.2e-181 S Oxidoreductase family, NAD-binding Rossmann fold
HDFOJLED_01912 3.3e-124 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HDFOJLED_01913 6.2e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDFOJLED_01914 3.8e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HDFOJLED_01915 5e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HDFOJLED_01916 9.9e-86 S ECF transporter, substrate-specific component
HDFOJLED_01917 7.3e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
HDFOJLED_01918 5.7e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDFOJLED_01919 4.5e-58 yabA L Involved in initiation control of chromosome replication
HDFOJLED_01920 1.7e-154 holB 2.7.7.7 L DNA polymerase III
HDFOJLED_01921 4.9e-51 yaaQ S Cyclic-di-AMP receptor
HDFOJLED_01922 8.7e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDFOJLED_01923 2.6e-33 S Protein of unknown function (DUF2508)
HDFOJLED_01924 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDFOJLED_01925 5e-38 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDFOJLED_01926 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDFOJLED_01927 6.9e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDFOJLED_01928 7.7e-117 rsmC 2.1.1.172 J Methyltransferase
HDFOJLED_01929 9e-83 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HDFOJLED_01930 4.9e-36 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HDFOJLED_01931 1.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDFOJLED_01932 3.5e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDFOJLED_01933 1.1e-154 yfdV S Membrane transport protein
HDFOJLED_01934 4.1e-10 yfdV S Membrane transport protein
HDFOJLED_01935 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
HDFOJLED_01936 7.8e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDFOJLED_01937 9.3e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDFOJLED_01938 7e-156 pstA P Phosphate transport system permease protein PstA
HDFOJLED_01939 1.9e-173 pstC P probably responsible for the translocation of the substrate across the membrane
HDFOJLED_01940 1.4e-156 pstS P Phosphate
HDFOJLED_01941 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDFOJLED_01942 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDFOJLED_01943 6.9e-101 nusG K Participates in transcription elongation, termination and antitermination
HDFOJLED_01944 5.9e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HDFOJLED_01945 4.4e-179 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDFOJLED_01946 9.6e-101 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDFOJLED_01947 1.3e-282 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HDFOJLED_01948 2.2e-34
HDFOJLED_01949 2.7e-94 sigH K Belongs to the sigma-70 factor family
HDFOJLED_01950 7.8e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDFOJLED_01951 6.7e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDFOJLED_01952 3.5e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDFOJLED_01953 7.3e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDFOJLED_01954 3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDFOJLED_01955 6.1e-102 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HDFOJLED_01956 4.5e-54
HDFOJLED_01957 1.6e-182 S Putative peptidoglycan binding domain
HDFOJLED_01958 1.8e-24
HDFOJLED_01959 1e-247 dtpT U amino acid peptide transporter
HDFOJLED_01960 0.0 pepN 3.4.11.2 E aminopeptidase
HDFOJLED_01962 1.2e-58 lysM M LysM domain
HDFOJLED_01963 5.7e-167
HDFOJLED_01964 6.3e-214 mdtG EGP Major facilitator Superfamily
HDFOJLED_01965 1.1e-81 S Threonine/Serine exporter, ThrE
HDFOJLED_01966 4.4e-138 thrE S Putative threonine/serine exporter
HDFOJLED_01967 5.4e-289 S ABC transporter
HDFOJLED_01968 5e-55
HDFOJLED_01969 7.8e-76 rimL J Acetyltransferase (GNAT) domain
HDFOJLED_01970 1.8e-114 S Protein of unknown function (DUF554)
HDFOJLED_01971 7.8e-214 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDFOJLED_01972 0.0 pepF E oligoendopeptidase F
HDFOJLED_01973 1.1e-22 Z012_06740 S Fic/DOC family
HDFOJLED_01974 7.3e-98 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HDFOJLED_01975 1.4e-239 aspT P Predicted Permease Membrane Region
HDFOJLED_01976 3.5e-152 asdA 4.1.1.12 E Aminotransferase
HDFOJLED_01978 2.6e-45 IQ Enoyl-(Acyl carrier protein) reductase
HDFOJLED_01979 1.3e-16
HDFOJLED_01980 1.3e-11 S Transglycosylase associated protein
HDFOJLED_01981 1.5e-84 S Asp23 family, cell envelope-related function
HDFOJLED_01982 8.1e-22 S Small integral membrane protein (DUF2273)
HDFOJLED_01983 1.8e-93
HDFOJLED_01984 8.4e-21
HDFOJLED_01985 9.5e-25 cspC K Probable zinc-ribbon domain
HDFOJLED_01988 6.9e-18
HDFOJLED_01989 1.6e-69 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HDFOJLED_01990 3.5e-11
HDFOJLED_01991 5.1e-164 repB EP Plasmid replication protein
HDFOJLED_01992 1e-27
HDFOJLED_01993 2.1e-211 L Belongs to the 'phage' integrase family
HDFOJLED_01994 2.6e-244 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDFOJLED_01995 2.2e-17 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HDFOJLED_01996 9.4e-179 tcsA S ABC transporter substrate-binding protein PnrA-like
HDFOJLED_01997 3.6e-248 xylG 3.6.3.17 S ABC transporter
HDFOJLED_01998 1.7e-167 yufP S Belongs to the binding-protein-dependent transport system permease family
HDFOJLED_01999 2e-161 yufQ S Belongs to the binding-protein-dependent transport system permease family
HDFOJLED_02000 0.0 3.6.3.8 P P-type ATPase
HDFOJLED_02001 1.8e-26 clcA P chloride
HDFOJLED_02002 1.6e-45
HDFOJLED_02003 1.5e-155 mutR K Helix-turn-helix XRE-family like proteins
HDFOJLED_02004 5.1e-76 S Putative adhesin
HDFOJLED_02005 4.4e-262 V ABC transporter transmembrane region
HDFOJLED_02006 3.6e-47 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HDFOJLED_02007 1.5e-49 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HDFOJLED_02008 1.2e-203 napA P Sodium/hydrogen exchanger family
HDFOJLED_02009 0.0 cadA P P-type ATPase
HDFOJLED_02010 9.5e-19 K DNA-templated transcription, initiation
HDFOJLED_02011 2.8e-21 K DNA-templated transcription, initiation
HDFOJLED_02012 2.3e-100
HDFOJLED_02013 4.1e-223 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HDFOJLED_02014 3.9e-209 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HDFOJLED_02015 0.0 yjbQ P TrkA C-terminal domain protein
HDFOJLED_02016 1e-129 gepA K Protein of unknown function (DUF4065)
HDFOJLED_02017 2.2e-82 S Oxidoreductase family, NAD-binding Rossmann fold
HDFOJLED_02021 7.9e-188 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
HDFOJLED_02023 1.1e-271 V ABC-type multidrug transport system, ATPase and permease components
HDFOJLED_02024 2.6e-286 V ABC-type multidrug transport system, ATPase and permease components
HDFOJLED_02025 1.4e-229 oppA E ABC transporter
HDFOJLED_02026 4.6e-24 Q Imidazolonepropionase and related amidohydrolases
HDFOJLED_02027 4.9e-185 Q Imidazolonepropionase and related amidohydrolases
HDFOJLED_02028 3e-61 psiE S Phosphate-starvation-inducible E
HDFOJLED_02030 3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDFOJLED_02031 1.3e-287 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HDFOJLED_02032 5.9e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HDFOJLED_02033 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HDFOJLED_02034 9.1e-135 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDFOJLED_02035 1.3e-40 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDFOJLED_02036 7.3e-73 S CRISPR-associated protein (Cas_Csn2)
HDFOJLED_02037 1.4e-130 cobB K SIR2 family
HDFOJLED_02038 3.5e-85
HDFOJLED_02039 1.7e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDFOJLED_02040 6.8e-178 S Alpha/beta hydrolase of unknown function (DUF915)
HDFOJLED_02041 3.6e-145 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDFOJLED_02042 2.4e-138 ypuA S Protein of unknown function (DUF1002)
HDFOJLED_02043 1.2e-159 epsV 2.7.8.12 S glycosyl transferase family 2
HDFOJLED_02044 5.6e-126 S Alpha/beta hydrolase family
HDFOJLED_02045 1.5e-115 GM NmrA-like family
HDFOJLED_02046 2.5e-55
HDFOJLED_02047 1.4e-181 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDFOJLED_02048 6e-123 luxT K Bacterial regulatory proteins, tetR family
HDFOJLED_02049 1e-129
HDFOJLED_02050 3.5e-261 glnPH2 P ABC transporter permease
HDFOJLED_02051 1.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDFOJLED_02052 3.2e-231 S Cysteine-rich secretory protein family
HDFOJLED_02053 2.4e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HDFOJLED_02054 2.2e-94
HDFOJLED_02055 1.7e-199 yibE S overlaps another CDS with the same product name
HDFOJLED_02056 2.2e-129 yibF S overlaps another CDS with the same product name
HDFOJLED_02057 3.8e-156 I alpha/beta hydrolase fold
HDFOJLED_02058 0.0 G Belongs to the glycosyl hydrolase 31 family
HDFOJLED_02059 5.7e-80 ntd 2.4.2.6 F Nucleoside
HDFOJLED_02060 5.6e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDFOJLED_02061 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HDFOJLED_02062 5.5e-86 uspA T universal stress protein
HDFOJLED_02064 1.8e-149 phnD P Phosphonate ABC transporter
HDFOJLED_02065 5.7e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HDFOJLED_02066 1.6e-127 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HDFOJLED_02067 4.6e-146 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HDFOJLED_02068 7.8e-108 tag 3.2.2.20 L glycosylase
HDFOJLED_02069 1.1e-81
HDFOJLED_02070 1.1e-272 S Calcineurin-like phosphoesterase
HDFOJLED_02071 0.0 asnB 6.3.5.4 E Asparagine synthase
HDFOJLED_02072 2.3e-253 yxbA 6.3.1.12 S ATP-grasp enzyme
HDFOJLED_02075 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HDFOJLED_02076 9.6e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDFOJLED_02077 7.8e-100 S Iron-sulfur cluster assembly protein
HDFOJLED_02078 7.5e-230 XK27_04775 S PAS domain
HDFOJLED_02079 5.7e-225 yttB EGP Major facilitator Superfamily
HDFOJLED_02080 0.0 pepO 3.4.24.71 O Peptidase family M13
HDFOJLED_02081 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDFOJLED_02082 2.6e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDFOJLED_02083 4.3e-169 xerC D Phage integrase, N-terminal SAM-like domain
HDFOJLED_02084 3e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDFOJLED_02085 1.9e-232 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDFOJLED_02086 1.6e-176 lacX 5.1.3.3 G Aldose 1-epimerase
HDFOJLED_02087 3.6e-129 arbV 2.3.1.51 I Acyl-transferase
HDFOJLED_02088 1.7e-143 arbx M Glycosyl transferase family 8
HDFOJLED_02089 2.5e-183 arbY M Glycosyl transferase family 8
HDFOJLED_02090 5.3e-162 arbY M Glycosyl transferase family 8
HDFOJLED_02091 7.3e-166 arbZ I Phosphate acyltransferases
HDFOJLED_02092 1.3e-34 S Cytochrome b5
HDFOJLED_02093 3.8e-108 K Transcriptional regulator, LysR family
HDFOJLED_02094 1.4e-100 K LysR substrate binding domain
HDFOJLED_02095 2e-41 K LysR substrate binding domain
HDFOJLED_02096 1.5e-94 ywnH 2.3.1.183 M acetyltransferase (GNAT) family
HDFOJLED_02097 4.1e-14 K Copper transport repressor CopY TcrY
HDFOJLED_02098 0.0 copB 3.6.3.4 P P-type ATPase
HDFOJLED_02099 4.5e-152 mdt(A) EGP Major facilitator Superfamily
HDFOJLED_02100 1e-36 mdt(A) EGP Major facilitator Superfamily
HDFOJLED_02101 6.8e-21
HDFOJLED_02102 1.8e-41
HDFOJLED_02103 5.7e-26
HDFOJLED_02104 3.5e-20 repA S Replication initiator protein A
HDFOJLED_02105 3.6e-164 S SLAP domain
HDFOJLED_02106 3.1e-38 S Protein of unknown function (DUF2922)
HDFOJLED_02107 1e-15
HDFOJLED_02109 2.5e-74
HDFOJLED_02110 0.0 kup P Transport of potassium into the cell
HDFOJLED_02111 1e-84 S Aminoacyl-tRNA editing domain
HDFOJLED_02112 4.9e-155 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDFOJLED_02113 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HDFOJLED_02114 3.1e-136 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDFOJLED_02115 1.5e-61 yodB K Transcriptional regulator, HxlR family
HDFOJLED_02116 2e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDFOJLED_02117 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDFOJLED_02119 1.5e-19 pfoS S Phosphotransferase system, EIIC
HDFOJLED_02120 1.3e-114 pfoS S Phosphotransferase system, EIIC
HDFOJLED_02121 3.8e-258 slpX S SLAP domain
HDFOJLED_02122 1.1e-35
HDFOJLED_02123 1.6e-45
HDFOJLED_02126 7.8e-213
HDFOJLED_02127 1.6e-123 gntR1 K UTRA
HDFOJLED_02128 1.8e-55 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HDFOJLED_02129 9.7e-86
HDFOJLED_02130 3.9e-44 relB L Addiction module antitoxin, RelB DinJ family
HDFOJLED_02131 8.9e-50 repA S Replication initiator protein A
HDFOJLED_02132 3.2e-71 repA S Replication initiator protein A
HDFOJLED_02133 5.3e-75 sdrF M domain protein
HDFOJLED_02134 4e-99 infB M YSIRK type signal peptide
HDFOJLED_02135 1.2e-16 sdrF M domain protein
HDFOJLED_02136 8.4e-139 pnuC H nicotinamide mononucleotide transporter
HDFOJLED_02137 4.1e-11
HDFOJLED_02138 1.3e-13 ropB K Transcriptional regulator
HDFOJLED_02139 1.9e-117 EGP Major facilitator Superfamily
HDFOJLED_02140 4.4e-29 S SLAP domain
HDFOJLED_02141 2.6e-23 3.2.1.4 GH5,GH9 M domain protein
HDFOJLED_02142 2.1e-26
HDFOJLED_02146 6.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDFOJLED_02147 5.2e-281 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDFOJLED_02148 3.8e-204 csaB M Glycosyl transferases group 1
HDFOJLED_02149 5.6e-135 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HDFOJLED_02150 3.8e-45 msmR7 K helix_turn_helix, arabinose operon control protein
HDFOJLED_02151 9.1e-98 msmR7 K helix_turn_helix, arabinose operon control protein
HDFOJLED_02152 1.1e-130 scrB 3.2.1.26 GH32 G invertase
HDFOJLED_02153 3e-216 scrA 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDFOJLED_02154 2.6e-14 scrA 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDFOJLED_02155 4.7e-97 rafA 3.2.1.22 G alpha-galactosidase
HDFOJLED_02156 3.7e-64 rafA 3.2.1.22 G alpha-galactosidase
HDFOJLED_02157 3e-187 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HDFOJLED_02158 3.1e-134 manY G PTS system
HDFOJLED_02159 2.2e-173 manN G system, mannose fructose sorbose family IID component
HDFOJLED_02160 7.6e-64 manO S Domain of unknown function (DUF956)
HDFOJLED_02161 2.4e-104 K Transcriptional regulator
HDFOJLED_02162 1.2e-22 K Transcriptional regulator
HDFOJLED_02163 1.4e-82 maa S transferase hexapeptide repeat
HDFOJLED_02164 8.6e-238 cycA E Amino acid permease
HDFOJLED_02165 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HDFOJLED_02166 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDFOJLED_02167 8.8e-47
HDFOJLED_02168 1e-102 yagE E amino acid
HDFOJLED_02169 1e-72
HDFOJLED_02170 2.5e-97 S LPXTG cell wall anchor motif
HDFOJLED_02171 1.4e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDFOJLED_02172 1.3e-136 4.1.1.44 S Carboxymuconolactone decarboxylase family
HDFOJLED_02173 6.4e-37
HDFOJLED_02174 7.7e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HDFOJLED_02175 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HDFOJLED_02176 2e-258 S TerB-C domain
HDFOJLED_02177 2.3e-251 P P-loop Domain of unknown function (DUF2791)
HDFOJLED_02178 0.0 lhr L DEAD DEAH box helicase
HDFOJLED_02179 1.5e-59
HDFOJLED_02180 2.9e-139 S Uncharacterized protein conserved in bacteria (DUF2263)
HDFOJLED_02181 1.1e-14 K Bacterial regulatory helix-turn-helix protein, lysR family
HDFOJLED_02182 3e-49 C FAD binding domain
HDFOJLED_02183 3.1e-26 C FAD binding domain
HDFOJLED_02184 2.1e-29 C FAD binding domain
HDFOJLED_02185 4.4e-28 C FAD binding domain
HDFOJLED_02187 1.9e-127 XK27_08435 K UTRA
HDFOJLED_02188 3.1e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDFOJLED_02189 9.9e-61 rpiR1 K Helix-turn-helix domain, rpiR family
HDFOJLED_02190 4.1e-71 S Iron-sulphur cluster biosynthesis
HDFOJLED_02191 7.1e-32
HDFOJLED_02192 2.1e-67
HDFOJLED_02193 1.5e-95 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HDFOJLED_02194 1.1e-25 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HDFOJLED_02195 5.6e-13
HDFOJLED_02196 3e-45 M LysM domain protein
HDFOJLED_02197 1.7e-196 D nuclear chromosome segregation
HDFOJLED_02198 3.4e-111 G Phosphoglycerate mutase family
HDFOJLED_02199 8.5e-229 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HDFOJLED_02200 3.2e-132 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HDFOJLED_02201 8.1e-123
HDFOJLED_02202 7.6e-85 M LysM domain
HDFOJLED_02204 3.6e-106 K Helix-turn-helix domain
HDFOJLED_02205 3.2e-115 L Integrase
HDFOJLED_02206 6.7e-63
HDFOJLED_02207 4.2e-76
HDFOJLED_02210 2.1e-82 S COG NOG38524 non supervised orthologous group
HDFOJLED_02211 5.1e-87 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDFOJLED_02214 2.7e-114 3.6.3.44 V ABC transporter transmembrane region
HDFOJLED_02215 9.4e-25 S amino acid activation for nonribosomal peptide biosynthetic process
HDFOJLED_02216 4.8e-82 S Domain of unknown function (DUF5067)
HDFOJLED_02217 4.8e-63
HDFOJLED_02218 4.3e-120 XK27_07525 3.6.1.55 F NUDIX domain
HDFOJLED_02219 6.2e-145 2.4.2.3 F Phosphorylase superfamily
HDFOJLED_02220 1.2e-73 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
HDFOJLED_02222 2.1e-79 K Acetyltransferase (GNAT) domain
HDFOJLED_02223 4.2e-53
HDFOJLED_02224 5.4e-42 oppA E ABC transporter
HDFOJLED_02225 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HDFOJLED_02226 4e-218 naiP EGP Major facilitator Superfamily
HDFOJLED_02227 5.1e-68 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HDFOJLED_02228 5.6e-22 pre D Plasmid recombination enzyme
HDFOJLED_02229 4.8e-70 pre D plasmid recombination enzyme
HDFOJLED_02230 1.1e-69 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDFOJLED_02231 3.3e-70 ropB K Transcriptional regulator
HDFOJLED_02232 3.3e-08
HDFOJLED_02233 2.7e-95 S Fic/DOC family
HDFOJLED_02234 1.8e-99 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HDFOJLED_02235 2.1e-256 mntH P H( )-stimulated, divalent metal cation uptake system
HDFOJLED_02236 1.3e-57 T Universal stress protein family
HDFOJLED_02237 7.3e-45 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HDFOJLED_02238 5.5e-110 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDFOJLED_02239 2.7e-183 XK27_05540 S DUF218 domain
HDFOJLED_02240 6.9e-78
HDFOJLED_02241 5.5e-110
HDFOJLED_02242 7.8e-150 EG EamA-like transporter family
HDFOJLED_02243 9.5e-83 M NlpC/P60 family
HDFOJLED_02244 0.0 traA L MobA MobL family protein
HDFOJLED_02245 5.2e-25
HDFOJLED_02246 4.4e-40
HDFOJLED_02247 1.5e-125 S Fic/DOC family
HDFOJLED_02248 4.3e-27

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)