ORF_ID e_value Gene_name EC_number CAZy COGs Description
HACLHNLC_00001 1.1e-56 yisS 1.1.1.370 S Oxidoreductase family, NAD-binding Rossmann fold
HACLHNLC_00002 6.6e-159 yisR K Transcriptional regulator
HACLHNLC_00003 2.5e-245 yisQ V Mate efflux family protein
HACLHNLC_00004 1.2e-132 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HACLHNLC_00005 0.0 asnO 6.3.5.4 E Asparagine synthase
HACLHNLC_00006 7.6e-97 yisN S Protein of unknown function (DUF2777)
HACLHNLC_00007 1.1e-59 yisL S UPF0344 protein
HACLHNLC_00008 1.2e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HACLHNLC_00009 5e-07 yisI S Spo0E like sporulation regulatory protein
HACLHNLC_00010 8.4e-34 gerPA S Spore germination protein
HACLHNLC_00011 6.2e-35 gerPB S cell differentiation
HACLHNLC_00012 1.4e-62 gerPC S Spore germination protein
HACLHNLC_00013 3.1e-23 gerPD S Spore germination protein
HACLHNLC_00014 3.1e-63 gerPE S Spore germination protein GerPE
HACLHNLC_00015 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
HACLHNLC_00016 2.9e-50 yisB V COG1403 Restriction endonuclease
HACLHNLC_00017 0.0 sbcC L COG0419 ATPase involved in DNA repair
HACLHNLC_00018 3.3e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HACLHNLC_00019 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HACLHNLC_00020 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HACLHNLC_00021 1.1e-124 ydfS S Protein of unknown function (DUF421)
HACLHNLC_00022 9.7e-94 yhjR S Rubrerythrin
HACLHNLC_00023 4.6e-106 K QacR-like protein, C-terminal region
HACLHNLC_00024 2.3e-202 blt EGP Major facilitator Superfamily
HACLHNLC_00025 4.8e-181 abrB S membrane
HACLHNLC_00026 1.1e-92 yhjH K helix_turn_helix multiple antibiotic resistance protein
HACLHNLC_00027 5.9e-277 yhjG CH FAD binding domain
HACLHNLC_00029 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HACLHNLC_00030 4.5e-109 yhjE S SNARE associated Golgi protein
HACLHNLC_00031 2.2e-60 yhjD
HACLHNLC_00032 1.4e-27 yhjC S Protein of unknown function (DUF3311)
HACLHNLC_00033 3.2e-267 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HACLHNLC_00034 3.3e-47 S Belongs to the UPF0145 family
HACLHNLC_00035 1.6e-42 yhjA S Excalibur calcium-binding domain
HACLHNLC_00036 5.1e-125 yrpD S Domain of unknown function, YrpD
HACLHNLC_00037 1.3e-168 els S Acetyltransferase, GNAT family
HACLHNLC_00038 2.4e-92 mepB S MepB protein
HACLHNLC_00039 1.4e-65 frataxin S Domain of unknown function (DU1801)
HACLHNLC_00040 3.9e-68 frataxin S Domain of unknown function (DU1801)
HACLHNLC_00041 1.9e-109 comK K Competence transcription factor
HACLHNLC_00042 1.8e-31 yhzC S IDEAL
HACLHNLC_00043 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACLHNLC_00044 3.1e-297 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HACLHNLC_00045 4.5e-196 hemAT NT chemotaxis protein
HACLHNLC_00046 5.1e-88 bioY S BioY family
HACLHNLC_00047 5.6e-280 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HACLHNLC_00048 1.5e-200 vraB 2.3.1.9 I Belongs to the thiolase family
HACLHNLC_00049 1.7e-102 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HACLHNLC_00050 9.3e-153 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HACLHNLC_00051 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HACLHNLC_00052 1.7e-237 yhfN 3.4.24.84 O Peptidase M48
HACLHNLC_00053 1.9e-65 yhfM
HACLHNLC_00054 6.4e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HACLHNLC_00055 7.7e-112 yhfK GM NmrA-like family
HACLHNLC_00056 1e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
HACLHNLC_00057 1.1e-138 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HACLHNLC_00058 3.4e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HACLHNLC_00059 4.3e-197 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HACLHNLC_00061 9.6e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HACLHNLC_00062 5e-270 yhgE S YhgE Pip N-terminal domain protein
HACLHNLC_00063 1.2e-100 yhgD K Transcriptional regulator
HACLHNLC_00064 1e-273 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HACLHNLC_00065 2.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HACLHNLC_00066 4.3e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HACLHNLC_00067 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HACLHNLC_00068 7.8e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HACLHNLC_00069 1.1e-243 yhfA C membrane
HACLHNLC_00070 1.6e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HACLHNLC_00071 6.2e-123 ecsC S EcsC protein family
HACLHNLC_00072 5e-221 ecsB U ABC transporter
HACLHNLC_00073 1.7e-134 ecsA V transporter (ATP-binding protein)
HACLHNLC_00074 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HACLHNLC_00075 1e-201 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HACLHNLC_00076 2.9e-77 trpP S Tryptophan transporter TrpP
HACLHNLC_00077 2e-17
HACLHNLC_00078 1.4e-38 yhaH S YtxH-like protein
HACLHNLC_00079 3.3e-112 hpr K Negative regulator of protease production and sporulation
HACLHNLC_00080 9.9e-55 yhaI S Protein of unknown function (DUF1878)
HACLHNLC_00081 7e-95 yhaK S Putative zincin peptidase
HACLHNLC_00082 2.6e-115 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HACLHNLC_00083 1.6e-32 yhaL S Sporulation protein YhaL
HACLHNLC_00084 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HACLHNLC_00085 0.0 yhaN L AAA domain
HACLHNLC_00086 5e-237 yhaO L DNA repair exonuclease
HACLHNLC_00087 8e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HACLHNLC_00088 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HACLHNLC_00089 7.3e-15 S YhzD-like protein
HACLHNLC_00090 2e-135 yhaR 5.3.3.18 I enoyl-CoA hydratase
HACLHNLC_00092 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HACLHNLC_00093 4.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
HACLHNLC_00094 5.8e-252 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
HACLHNLC_00095 9.3e-294 hemZ H coproporphyrinogen III oxidase
HACLHNLC_00096 3.3e-158 yhaX S haloacid dehalogenase-like hydrolase
HACLHNLC_00097 2.6e-203 yhaZ L DNA alkylation repair enzyme
HACLHNLC_00098 4.4e-53 yheA S Belongs to the UPF0342 family
HACLHNLC_00099 3.6e-205 yheB S Belongs to the UPF0754 family
HACLHNLC_00100 6.9e-214 yheC HJ YheC/D like ATP-grasp
HACLHNLC_00101 2.5e-261 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HACLHNLC_00102 1.7e-36 yheE S Family of unknown function (DUF5342)
HACLHNLC_00103 5.8e-29 sspB S spore protein
HACLHNLC_00105 4.8e-111 yheG GM NAD(P)H-binding
HACLHNLC_00106 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HACLHNLC_00107 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HACLHNLC_00109 4e-84 T universal stress protein
HACLHNLC_00110 1.8e-93 ymcC S Membrane
HACLHNLC_00111 4.6e-88 pksA K Transcriptional regulator
HACLHNLC_00112 5.3e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HACLHNLC_00113 1e-156 yheN G deacetylase
HACLHNLC_00114 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HACLHNLC_00115 1.6e-205 yhdY M Mechanosensitive ion channel
HACLHNLC_00117 1e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HACLHNLC_00118 2.1e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HACLHNLC_00119 6.1e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HACLHNLC_00120 3.5e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HACLHNLC_00121 5.6e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HACLHNLC_00122 5.5e-225 yhdR 2.6.1.1 E Aminotransferase
HACLHNLC_00123 4.3e-71 cueR K transcriptional
HACLHNLC_00124 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HACLHNLC_00125 1.9e-109 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HACLHNLC_00126 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HACLHNLC_00127 1.3e-201 yhdL S Sigma factor regulator N-terminal
HACLHNLC_00128 8.1e-45 yhdK S Sigma-M inhibitor protein
HACLHNLC_00129 4.4e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HACLHNLC_00130 1.7e-249 yhdG E amino acid
HACLHNLC_00131 1.3e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACLHNLC_00132 2.7e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
HACLHNLC_00133 9e-164 citR K Transcriptional regulator
HACLHNLC_00134 6.3e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HACLHNLC_00135 7.5e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HACLHNLC_00136 3.6e-271 ycgB S Stage V sporulation protein R
HACLHNLC_00137 2.7e-256 ygxB M Conserved TM helix
HACLHNLC_00138 1.6e-73 nsrR K Transcriptional regulator
HACLHNLC_00139 6.8e-217 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HACLHNLC_00140 1.1e-53 yhdC S Protein of unknown function (DUF3889)
HACLHNLC_00141 2.5e-39 yhdB S YhdB-like protein
HACLHNLC_00142 7.4e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
HACLHNLC_00143 2.5e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACLHNLC_00144 1.3e-207 yhcY 2.7.13.3 T Histidine kinase
HACLHNLC_00145 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HACLHNLC_00146 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HACLHNLC_00147 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HACLHNLC_00148 1.2e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HACLHNLC_00149 3.4e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HACLHNLC_00150 3.2e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HACLHNLC_00151 3.9e-210 tcaB EGP Major facilitator Superfamily
HACLHNLC_00152 3e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HACLHNLC_00153 3.2e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
HACLHNLC_00154 4.2e-100 ynaD J Acetyltransferase (GNAT) domain
HACLHNLC_00155 2.7e-299 expZ S ABC transporter
HACLHNLC_00156 4.7e-134 puuD S Peptidase C26
HACLHNLC_00157 0.0 ydfJ S drug exporters of the RND superfamily
HACLHNLC_00158 8.3e-111 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACLHNLC_00159 1.8e-213 ydfH 2.7.13.3 T Histidine kinase
HACLHNLC_00160 1.2e-36 yraG
HACLHNLC_00161 6.4e-63 yraF M Spore coat protein
HACLHNLC_00162 4.2e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HACLHNLC_00163 7.5e-26 yraE
HACLHNLC_00164 9.5e-49 yraD M Spore coat protein
HACLHNLC_00165 3.1e-267 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HACLHNLC_00166 1.5e-155 ydeK EG -transporter
HACLHNLC_00167 8.4e-102 ydeS K Transcriptional regulator
HACLHNLC_00168 1.9e-180 ydeR EGP Major facilitator Superfamily
HACLHNLC_00170 7.1e-115 paiB K Transcriptional regulator
HACLHNLC_00171 9.2e-264 K helix_turn_helix gluconate operon transcriptional repressor
HACLHNLC_00172 6.2e-222 mleN_2 C antiporter
HACLHNLC_00173 3.6e-67 yraB K helix_turn_helix, mercury resistance
HACLHNLC_00174 2.2e-201 adhA 1.1.1.1 C alcohol dehydrogenase
HACLHNLC_00175 1.6e-166 S Sodium Bile acid symporter family
HACLHNLC_00176 2.6e-51 ydeH
HACLHNLC_00177 4.6e-199 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HACLHNLC_00179 2e-148 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
HACLHNLC_00180 5.2e-66 ykkA S Protein of unknown function (DUF664)
HACLHNLC_00181 9e-98 yrkC G Cupin domain
HACLHNLC_00183 6.4e-201 trkA P Oxidoreductase
HACLHNLC_00184 3.8e-168 czcD P COG1230 Co Zn Cd efflux system component
HACLHNLC_00185 2e-76 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HACLHNLC_00186 6e-268 ygaK C COG0277 FAD FMN-containing dehydrogenases
HACLHNLC_00189 1e-47 G Cupin domain
HACLHNLC_00190 1.7e-84 S DinB superfamily
HACLHNLC_00191 1.6e-182 S Patatin-like phospholipase
HACLHNLC_00192 1.1e-234 ybfB G COG0477 Permeases of the major facilitator superfamily
HACLHNLC_00193 1.1e-86 ybfA 3.4.15.5 K FR47-like protein
HACLHNLC_00194 1.3e-51 K Transcriptional regulator PadR-like family
HACLHNLC_00195 2.8e-102 S Protein of unknown function (DUF2812)
HACLHNLC_00196 6.6e-122 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HACLHNLC_00197 4.7e-79 carD K Transcription factor
HACLHNLC_00198 5.2e-30 cspL K Cold shock
HACLHNLC_00199 1.8e-195 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HACLHNLC_00200 2.2e-54 K Transcriptional regulator
HACLHNLC_00201 3.5e-177 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HACLHNLC_00202 8.7e-75 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HACLHNLC_00203 0.0 M Domain of unknown function DUF11
HACLHNLC_00204 1.4e-108 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HACLHNLC_00205 7.7e-50 S SMI1-KNR4 cell-wall
HACLHNLC_00207 3.8e-111 ywnB S NAD(P)H-binding
HACLHNLC_00208 4.8e-73 ywnA K Transcriptional regulator
HACLHNLC_00209 3.2e-64 yyaQ S YjbR
HACLHNLC_00210 1e-72 maoC I N-terminal half of MaoC dehydratase
HACLHNLC_00211 8.5e-57 S Domain of unknown function with cystatin-like fold (DUF4467)
HACLHNLC_00212 4.5e-49 ohrR K Transcriptional regulator
HACLHNLC_00213 5.2e-230 proP EGP Transporter
HACLHNLC_00214 1.6e-25 G Cupin domain
HACLHNLC_00215 1.4e-150 S Serine aminopeptidase, S33
HACLHNLC_00216 3.5e-70 lrpA K transcriptional
HACLHNLC_00217 1.4e-141 yddR S Zn-dependent hydrolases of the beta-lactamase fold
HACLHNLC_00218 6.5e-72 S SnoaL-like polyketide cyclase
HACLHNLC_00219 2.8e-96 ywrO S Flavodoxin-like fold
HACLHNLC_00220 5.5e-08
HACLHNLC_00228 2.8e-57 ydcK S Belongs to the SprT family
HACLHNLC_00229 1.7e-14
HACLHNLC_00230 0.0 yhgF K COG2183 Transcriptional accessory protein
HACLHNLC_00231 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HACLHNLC_00232 6.9e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACLHNLC_00233 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HACLHNLC_00234 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HACLHNLC_00235 2.3e-187 rsbU 3.1.3.3 KT phosphatase
HACLHNLC_00236 1.9e-68 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HACLHNLC_00237 6.8e-57 rsbS T antagonist
HACLHNLC_00238 6.1e-146 rsbR T Positive regulator of sigma-B
HACLHNLC_00239 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HACLHNLC_00240 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HACLHNLC_00241 5.3e-220 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HACLHNLC_00242 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HACLHNLC_00243 4.7e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HACLHNLC_00244 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HACLHNLC_00245 3.7e-263 ydbT S Membrane
HACLHNLC_00246 8.1e-82 ydbS S Bacterial PH domain
HACLHNLC_00247 3.4e-248 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HACLHNLC_00248 3.1e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HACLHNLC_00249 3.5e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HACLHNLC_00250 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HACLHNLC_00251 6.9e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HACLHNLC_00252 1.5e-10 S Fur-regulated basic protein B
HACLHNLC_00253 3.8e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HACLHNLC_00254 6.1e-52 ydbL
HACLHNLC_00255 3.7e-113 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HACLHNLC_00256 1.5e-172 ydbJ V ABC transporter, ATP-binding protein
HACLHNLC_00257 1.3e-156 ydbI S AI-2E family transporter
HACLHNLC_00258 5e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HACLHNLC_00259 7.4e-118 dctR T COG4565 Response regulator of citrate malate metabolism
HACLHNLC_00260 1.2e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HACLHNLC_00261 1.6e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HACLHNLC_00262 6.5e-156 ydbD P Catalase
HACLHNLC_00263 5.3e-62 ydbC S Domain of unknown function (DUF4937
HACLHNLC_00264 7.5e-58 ydbB G Cupin domain
HACLHNLC_00266 1.5e-141 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HACLHNLC_00267 7e-54 yvaE P Small Multidrug Resistance protein
HACLHNLC_00268 1.7e-69 yvaD S Family of unknown function (DUF5360)
HACLHNLC_00269 1.4e-33 ydaT
HACLHNLC_00271 3.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
HACLHNLC_00272 2.1e-39
HACLHNLC_00273 4.3e-98
HACLHNLC_00274 5.3e-77
HACLHNLC_00276 1.1e-20 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HACLHNLC_00277 4.2e-35 xkdS S Protein of unknown function (DUF2634)
HACLHNLC_00278 1.1e-108 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HACLHNLC_00279 2.9e-33 xkdR S Protein of unknown function (DUF2577)
HACLHNLC_00280 7.3e-87 yqbQ 3.2.1.96 G NLP P60 protein
HACLHNLC_00282 4.3e-15
HACLHNLC_00283 6.7e-67 K acetyltransferase
HACLHNLC_00284 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HACLHNLC_00285 9.4e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HACLHNLC_00286 0.0 ydaO E amino acid
HACLHNLC_00287 0.0 ydaN S Bacterial cellulose synthase subunit
HACLHNLC_00288 2.7e-230 ydaM M Glycosyl transferase family group 2
HACLHNLC_00289 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HACLHNLC_00290 3e-148 ydaK T Diguanylate cyclase, GGDEF domain
HACLHNLC_00291 2.8e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HACLHNLC_00292 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HACLHNLC_00293 1.5e-74 lrpC K Transcriptional regulator
HACLHNLC_00294 1.3e-47 ydzA EGP Major facilitator Superfamily
HACLHNLC_00295 6.8e-69 yrrS S Protein of unknown function (DUF1510)
HACLHNLC_00296 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HACLHNLC_00297 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HACLHNLC_00298 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HACLHNLC_00299 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HACLHNLC_00300 6.6e-173 yegQ O Peptidase U32
HACLHNLC_00301 3.6e-117 yrrM 2.1.1.104 S O-methyltransferase
HACLHNLC_00302 5.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HACLHNLC_00303 7.1e-46 yrzB S Belongs to the UPF0473 family
HACLHNLC_00304 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HACLHNLC_00305 1.7e-41 yrzL S Belongs to the UPF0297 family
HACLHNLC_00306 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HACLHNLC_00307 6.4e-164 yrrI S AI-2E family transporter
HACLHNLC_00308 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HACLHNLC_00309 3.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
HACLHNLC_00310 1.2e-109 gluC P ABC transporter
HACLHNLC_00311 4.4e-107 glnP P ABC transporter
HACLHNLC_00312 2.1e-08 S Protein of unknown function (DUF3918)
HACLHNLC_00313 2.9e-30 yrzR
HACLHNLC_00314 1.8e-83 yrrD S protein conserved in bacteria
HACLHNLC_00315 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HACLHNLC_00316 1.7e-18 S COG0457 FOG TPR repeat
HACLHNLC_00317 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HACLHNLC_00318 5.2e-212 iscS 2.8.1.7 E Cysteine desulfurase
HACLHNLC_00319 7.8e-64 cymR K Transcriptional regulator
HACLHNLC_00320 1.7e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HACLHNLC_00321 7.4e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HACLHNLC_00322 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HACLHNLC_00323 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HACLHNLC_00326 6.3e-261 lytH 3.5.1.28 M COG3103 SH3 domain protein
HACLHNLC_00327 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HACLHNLC_00328 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HACLHNLC_00329 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HACLHNLC_00330 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HACLHNLC_00331 5.7e-47 yrvD S Lipopolysaccharide assembly protein A domain
HACLHNLC_00332 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HACLHNLC_00333 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HACLHNLC_00334 4.2e-49 yrzD S Post-transcriptional regulator
HACLHNLC_00335 9.4e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HACLHNLC_00336 9.5e-110 yrbG S membrane
HACLHNLC_00337 2.4e-60 yrzE S Protein of unknown function (DUF3792)
HACLHNLC_00338 5.6e-37 yajC U Preprotein translocase subunit YajC
HACLHNLC_00339 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HACLHNLC_00340 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HACLHNLC_00341 1.6e-20 yrzS S Protein of unknown function (DUF2905)
HACLHNLC_00342 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HACLHNLC_00343 1.3e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HACLHNLC_00344 3.7e-93 bofC S BofC C-terminal domain
HACLHNLC_00346 6.7e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HACLHNLC_00347 1.2e-147 safA M spore coat assembly protein SafA
HACLHNLC_00348 9.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HACLHNLC_00349 4.9e-151 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HACLHNLC_00350 6.5e-298 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HACLHNLC_00351 2.9e-223 nifS 2.8.1.7 E Cysteine desulfurase
HACLHNLC_00352 1.5e-92 niaR S small molecule binding protein (contains 3H domain)
HACLHNLC_00353 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
HACLHNLC_00354 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HACLHNLC_00355 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HACLHNLC_00356 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HACLHNLC_00357 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HACLHNLC_00358 3.2e-56 ysxB J ribosomal protein
HACLHNLC_00359 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HACLHNLC_00360 7.8e-160 spoIVFB S Stage IV sporulation protein
HACLHNLC_00361 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HACLHNLC_00362 8e-143 minD D Belongs to the ParA family
HACLHNLC_00363 8.7e-90 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HACLHNLC_00364 1.4e-84 mreD M shape-determining protein
HACLHNLC_00365 1.2e-157 mreC M Involved in formation and maintenance of cell shape
HACLHNLC_00366 4e-184 mreB D Rod shape-determining protein MreB
HACLHNLC_00367 1.8e-127 radC E Belongs to the UPF0758 family
HACLHNLC_00368 3.5e-100 maf D septum formation protein Maf
HACLHNLC_00369 3.3e-138 spoIIB S Sporulation related domain
HACLHNLC_00370 3.3e-104 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HACLHNLC_00371 6.2e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HACLHNLC_00372 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HACLHNLC_00373 2.1e-25
HACLHNLC_00374 2.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HACLHNLC_00375 2.3e-228 spoVID M stage VI sporulation protein D
HACLHNLC_00376 1.8e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HACLHNLC_00377 1.7e-184 hemB 4.2.1.24 H Belongs to the ALAD family
HACLHNLC_00378 1e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HACLHNLC_00379 6.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HACLHNLC_00380 3.6e-146 hemX O cytochrome C
HACLHNLC_00381 7.7e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HACLHNLC_00382 1.4e-86 ysxD
HACLHNLC_00383 3.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HACLHNLC_00384 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HACLHNLC_00385 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HACLHNLC_00386 2.2e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HACLHNLC_00387 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HACLHNLC_00388 4.1e-189 ysoA H Tetratricopeptide repeat
HACLHNLC_00389 2.4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HACLHNLC_00390 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HACLHNLC_00391 9.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HACLHNLC_00392 1.4e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HACLHNLC_00393 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HACLHNLC_00394 2.3e-82 ilvN 2.2.1.6 E Acetolactate synthase
HACLHNLC_00395 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HACLHNLC_00400 4.5e-91 ysnB S Phosphoesterase
HACLHNLC_00401 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HACLHNLC_00402 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HACLHNLC_00403 8.1e-199 gerM S COG5401 Spore germination protein
HACLHNLC_00404 7.8e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HACLHNLC_00405 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HACLHNLC_00406 2e-30 gerE K Transcriptional regulator
HACLHNLC_00407 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HACLHNLC_00408 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HACLHNLC_00409 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HACLHNLC_00410 4.8e-108 sdhC C succinate dehydrogenase
HACLHNLC_00411 1.2e-79 yslB S Protein of unknown function (DUF2507)
HACLHNLC_00412 1.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HACLHNLC_00413 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HACLHNLC_00414 2.5e-52 trxA O Belongs to the thioredoxin family
HACLHNLC_00415 6.2e-298 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HACLHNLC_00416 5.5e-178 etfA C Electron transfer flavoprotein
HACLHNLC_00417 2e-138 etfB C Electron transfer flavoprotein
HACLHNLC_00418 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HACLHNLC_00419 9.2e-104 fadR K Transcriptional regulator
HACLHNLC_00420 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HACLHNLC_00421 2.2e-117 ywbB S Protein of unknown function (DUF2711)
HACLHNLC_00422 4.1e-89 yisT S DinB family
HACLHNLC_00423 1.2e-74 argO S Lysine exporter protein LysE YggA
HACLHNLC_00424 2.6e-192 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HACLHNLC_00425 1.3e-71 mcbG S Pentapeptide repeats (9 copies)
HACLHNLC_00426 1.3e-78 yjcF S Acetyltransferase (GNAT) domain
HACLHNLC_00427 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HACLHNLC_00428 6.6e-55 yajQ S Belongs to the UPF0234 family
HACLHNLC_00429 1.2e-160 cvfB S protein conserved in bacteria
HACLHNLC_00430 2.6e-172 yufN S ABC transporter substrate-binding protein PnrA-like
HACLHNLC_00431 1.1e-231 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HACLHNLC_00432 1.4e-242 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HACLHNLC_00434 4.9e-159 yitS S protein conserved in bacteria
HACLHNLC_00435 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HACLHNLC_00436 2.7e-79 ipi S Intracellular proteinase inhibitor
HACLHNLC_00437 4.4e-26 S Protein of unknown function (DUF3813)
HACLHNLC_00438 3.5e-07
HACLHNLC_00439 1.7e-153 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HACLHNLC_00440 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HACLHNLC_00441 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HACLHNLC_00442 1.5e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HACLHNLC_00443 2.6e-269 yitY C D-arabinono-1,4-lactone oxidase
HACLHNLC_00444 1.2e-89 norB G Major Facilitator Superfamily
HACLHNLC_00445 5.2e-195 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HACLHNLC_00446 1.8e-226 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HACLHNLC_00447 5.4e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HACLHNLC_00448 5.8e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HACLHNLC_00449 6.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HACLHNLC_00450 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HACLHNLC_00451 2.3e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HACLHNLC_00452 1.2e-27 yjzC S YjzC-like protein
HACLHNLC_00453 1.5e-23 yjzD S Protein of unknown function (DUF2929)
HACLHNLC_00454 4.2e-138 yjaU I carboxylic ester hydrolase activity
HACLHNLC_00455 8.8e-104 yjaV
HACLHNLC_00456 7.2e-166 med S Transcriptional activator protein med
HACLHNLC_00457 1.1e-26 comZ S ComZ
HACLHNLC_00458 5.9e-32 yjzB
HACLHNLC_00459 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HACLHNLC_00460 7.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HACLHNLC_00461 1.6e-148 yjaZ O Zn-dependent protease
HACLHNLC_00462 1.4e-181 appD P Belongs to the ABC transporter superfamily
HACLHNLC_00463 2.2e-187 appF E Belongs to the ABC transporter superfamily
HACLHNLC_00464 4e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HACLHNLC_00465 7e-170 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACLHNLC_00466 3.6e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACLHNLC_00467 5.5e-146 yjbA S Belongs to the UPF0736 family
HACLHNLC_00468 8e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HACLHNLC_00469 0.0 oppA E ABC transporter substrate-binding protein
HACLHNLC_00470 1.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACLHNLC_00471 2.4e-159 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACLHNLC_00472 2.7e-202 oppD P Belongs to the ABC transporter superfamily
HACLHNLC_00473 2.7e-171 oppF E Belongs to the ABC transporter superfamily
HACLHNLC_00474 1.1e-231 S Putative glycosyl hydrolase domain
HACLHNLC_00475 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HACLHNLC_00476 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HACLHNLC_00477 9.5e-110 yjbE P Integral membrane protein TerC family
HACLHNLC_00478 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HACLHNLC_00479 3.3e-222 yjbF S Competence protein
HACLHNLC_00480 0.0 pepF E oligoendopeptidase F
HACLHNLC_00481 5.8e-19
HACLHNLC_00482 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HACLHNLC_00483 4.8e-72 yjbI S Bacterial-like globin
HACLHNLC_00484 1.9e-116 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HACLHNLC_00485 2.3e-99 yjbK S protein conserved in bacteria
HACLHNLC_00486 8.6e-60 yjbL S Belongs to the UPF0738 family
HACLHNLC_00487 2.3e-108 yjbM 2.7.6.5 S GTP pyrophosphokinase
HACLHNLC_00488 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HACLHNLC_00489 6.3e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HACLHNLC_00490 8.8e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HACLHNLC_00491 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HACLHNLC_00492 1.9e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HACLHNLC_00493 1.2e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HACLHNLC_00494 2.7e-213 thiO 1.4.3.19 E Glycine oxidase
HACLHNLC_00495 6.7e-30 thiS H Thiamine biosynthesis
HACLHNLC_00496 5.8e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HACLHNLC_00497 8.4e-190 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HACLHNLC_00498 3.7e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HACLHNLC_00499 8.8e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HACLHNLC_00500 5e-89 yjbX S Spore coat protein
HACLHNLC_00501 6.7e-83 cotZ S Spore coat protein
HACLHNLC_00502 9.2e-94 cotY S Spore coat protein Z
HACLHNLC_00503 4.4e-75 cotX S Spore Coat Protein X and V domain
HACLHNLC_00504 1.1e-23 cotW
HACLHNLC_00505 4.2e-57 cotV S Spore Coat Protein X and V domain
HACLHNLC_00506 7.3e-56 yjcA S Protein of unknown function (DUF1360)
HACLHNLC_00510 3.8e-38 spoVIF S Stage VI sporulation protein F
HACLHNLC_00511 0.0 yjcD 3.6.4.12 L DNA helicase
HACLHNLC_00512 1.8e-35
HACLHNLC_00513 5.2e-144 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HACLHNLC_00514 9.8e-124 S ABC-2 type transporter
HACLHNLC_00515 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
HACLHNLC_00516 9.4e-36 K SpoVT / AbrB like domain
HACLHNLC_00517 3.2e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HACLHNLC_00518 2.4e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HACLHNLC_00519 7.2e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
HACLHNLC_00520 1.4e-209 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HACLHNLC_00521 3e-215 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HACLHNLC_00524 1.3e-195 yerI S homoserine kinase type II (protein kinase fold)
HACLHNLC_00525 3.1e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
HACLHNLC_00526 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HACLHNLC_00527 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HACLHNLC_00528 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HACLHNLC_00529 1.7e-301 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HACLHNLC_00530 6.9e-50 yerC S protein conserved in bacteria
HACLHNLC_00531 2e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
HACLHNLC_00532 0.0 yerA 3.5.4.2 F adenine deaminase
HACLHNLC_00533 1.2e-25 S Protein of unknown function (DUF2892)
HACLHNLC_00534 5.3e-234 purD 6.3.4.13 F Belongs to the GARS family
HACLHNLC_00535 1.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HACLHNLC_00536 1.8e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HACLHNLC_00537 8.7e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HACLHNLC_00538 2.1e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HACLHNLC_00539 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HACLHNLC_00540 9.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HACLHNLC_00541 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HACLHNLC_00542 4.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HACLHNLC_00543 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HACLHNLC_00544 3.6e-224 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HACLHNLC_00545 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HACLHNLC_00546 6.1e-28 yebG S NETI protein
HACLHNLC_00547 3.1e-93 yebE S UPF0316 protein
HACLHNLC_00549 1.6e-124 yebC M Membrane
HACLHNLC_00550 1.4e-208 pbuG S permease
HACLHNLC_00551 2.1e-247 S Domain of unknown function (DUF4179)
HACLHNLC_00552 1.3e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HACLHNLC_00553 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HACLHNLC_00554 0.0 yebA E COG1305 Transglutaminase-like enzymes
HACLHNLC_00555 3e-215 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HACLHNLC_00556 1.3e-176 yeaC S COG0714 MoxR-like ATPases
HACLHNLC_00557 9.3e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HACLHNLC_00558 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HACLHNLC_00559 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HACLHNLC_00560 7.2e-35 ydjO S Cold-inducible protein YdjO
HACLHNLC_00562 3.4e-133 ydjN U Involved in the tonB-independent uptake of proteins
HACLHNLC_00563 1.4e-62 ydjM M Lytic transglycolase
HACLHNLC_00564 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HACLHNLC_00565 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HACLHNLC_00566 4.5e-144 rsiV S Protein of unknown function (DUF3298)
HACLHNLC_00567 0.0 yrhL I Acyltransferase family
HACLHNLC_00568 3.9e-155 ydjI S virion core protein (lumpy skin disease virus)
HACLHNLC_00569 1.3e-121 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HACLHNLC_00570 2.6e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HACLHNLC_00571 1.8e-114 pspA KT Phage shock protein A
HACLHNLC_00572 2.3e-29 yjdJ S Domain of unknown function (DUF4306)
HACLHNLC_00573 8.9e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HACLHNLC_00574 2e-250 gutA G MFS/sugar transport protein
HACLHNLC_00575 2.1e-199 gutB 1.1.1.14 E Dehydrogenase
HACLHNLC_00576 0.0 K NB-ARC domain
HACLHNLC_00577 7.6e-151 ydjC S Abhydrolase domain containing 18
HACLHNLC_00578 1.2e-145 3.1.21.5 KL Type III restriction enzyme res subunit
HACLHNLC_00579 7.2e-167 2.1.1.72 L DNA methylase
HACLHNLC_00580 9.1e-14
HACLHNLC_00581 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HACLHNLC_00582 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HACLHNLC_00583 5.6e-127 ydiL S CAAX protease self-immunity
HACLHNLC_00584 1.7e-27 ydiK S Domain of unknown function (DUF4305)
HACLHNLC_00585 1.8e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HACLHNLC_00586 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HACLHNLC_00587 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HACLHNLC_00588 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HACLHNLC_00589 0.0 ydiF S ABC transporter
HACLHNLC_00590 1.5e-189 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HACLHNLC_00591 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HACLHNLC_00592 3.8e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HACLHNLC_00593 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HACLHNLC_00594 3.7e-182 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HACLHNLC_00596 1.3e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HACLHNLC_00597 4e-77 ydaG 1.4.3.5 S general stress protein
HACLHNLC_00598 1e-105 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HACLHNLC_00599 1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HACLHNLC_00600 4.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACLHNLC_00601 4.8e-290 ydaB IQ acyl-CoA ligase
HACLHNLC_00602 0.0 mtlR K transcriptional regulator, MtlR
HACLHNLC_00603 7.5e-174 ydhF S Oxidoreductase
HACLHNLC_00604 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HACLHNLC_00605 1.1e-55 yczJ S biosynthesis
HACLHNLC_00607 1.2e-117 ycsK E anatomical structure formation involved in morphogenesis
HACLHNLC_00608 1.3e-129 kipR K Transcriptional regulator
HACLHNLC_00609 4.2e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HACLHNLC_00610 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HACLHNLC_00611 3.5e-151 ycsI S Belongs to the D-glutamate cyclase family
HACLHNLC_00612 1.4e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HACLHNLC_00613 6e-140 ycsF S Belongs to the UPF0271 (lamB) family
HACLHNLC_00614 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HACLHNLC_00616 5.1e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HACLHNLC_00617 4.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HACLHNLC_00618 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HACLHNLC_00619 2.3e-225 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HACLHNLC_00620 6e-55
HACLHNLC_00621 1.6e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HACLHNLC_00622 1e-298 ycnJ P protein, homolog of Cu resistance protein CopC
HACLHNLC_00623 7.8e-98 ycnI S protein conserved in bacteria
HACLHNLC_00624 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACLHNLC_00625 3.6e-149 glcU U Glucose uptake
HACLHNLC_00626 5.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HACLHNLC_00627 1.6e-220 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HACLHNLC_00628 6.1e-263 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HACLHNLC_00629 3.3e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HACLHNLC_00630 6.1e-45 ycnE S Monooxygenase
HACLHNLC_00631 5.2e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
HACLHNLC_00632 1.6e-152 ycnC K Transcriptional regulator
HACLHNLC_00633 3.6e-247 ycnB EGP Major facilitator Superfamily
HACLHNLC_00634 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HACLHNLC_00635 8.1e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HACLHNLC_00636 1.1e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACLHNLC_00637 6.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACLHNLC_00638 1.9e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
HACLHNLC_00640 1.5e-81 S aspartate phosphatase
HACLHNLC_00641 1.5e-261 T PhoQ Sensor
HACLHNLC_00642 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACLHNLC_00643 3.8e-236 yclI V ABC transporter (permease) YclI
HACLHNLC_00644 4.3e-121 yclH P ABC transporter
HACLHNLC_00645 1.5e-250 yxeQ S MmgE/PrpD family
HACLHNLC_00646 6.4e-218 yxeP 3.5.1.47 E hydrolase activity
HACLHNLC_00647 1e-131 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HACLHNLC_00648 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
HACLHNLC_00649 1.8e-142 yxeM M Belongs to the bacterial solute-binding protein 3 family
HACLHNLC_00650 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HACLHNLC_00651 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACLHNLC_00652 1.1e-195 gerKB F Spore germination protein
HACLHNLC_00653 2.1e-235 gerKC S spore germination
HACLHNLC_00654 5e-285 gerKA EG Spore germination protein
HACLHNLC_00656 9.8e-279 yclG M Pectate lyase superfamily protein
HACLHNLC_00657 5.4e-270 dtpT E amino acid peptide transporter
HACLHNLC_00658 7.5e-77 ctsR K Belongs to the CtsR family
HACLHNLC_00659 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HACLHNLC_00660 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HACLHNLC_00661 0.0 clpC O Belongs to the ClpA ClpB family
HACLHNLC_00662 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HACLHNLC_00663 6.4e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HACLHNLC_00664 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HACLHNLC_00665 9.4e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HACLHNLC_00666 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HACLHNLC_00667 1.1e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HACLHNLC_00668 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
HACLHNLC_00669 4e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HACLHNLC_00670 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HACLHNLC_00671 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HACLHNLC_00672 4.2e-89 yacP S RNA-binding protein containing a PIN domain
HACLHNLC_00673 8.9e-116 sigH K Belongs to the sigma-70 factor family
HACLHNLC_00674 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HACLHNLC_00675 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HACLHNLC_00676 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HACLHNLC_00677 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HACLHNLC_00678 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HACLHNLC_00679 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HACLHNLC_00680 5.3e-107 rsmC 2.1.1.172 J Methyltransferase
HACLHNLC_00681 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HACLHNLC_00682 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HACLHNLC_00683 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HACLHNLC_00684 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HACLHNLC_00685 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HACLHNLC_00686 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HACLHNLC_00687 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HACLHNLC_00688 2.2e-187 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HACLHNLC_00689 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HACLHNLC_00690 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HACLHNLC_00691 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
HACLHNLC_00692 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HACLHNLC_00693 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HACLHNLC_00694 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HACLHNLC_00695 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HACLHNLC_00696 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HACLHNLC_00697 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HACLHNLC_00698 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HACLHNLC_00699 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HACLHNLC_00700 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HACLHNLC_00701 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HACLHNLC_00702 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HACLHNLC_00703 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HACLHNLC_00704 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HACLHNLC_00705 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HACLHNLC_00706 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HACLHNLC_00707 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HACLHNLC_00708 1.9e-23 rpmD J Ribosomal protein L30
HACLHNLC_00709 4.1e-72 rplO J binds to the 23S rRNA
HACLHNLC_00710 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HACLHNLC_00711 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HACLHNLC_00712 6.3e-142 map 3.4.11.18 E Methionine aminopeptidase
HACLHNLC_00713 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HACLHNLC_00714 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HACLHNLC_00715 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HACLHNLC_00716 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HACLHNLC_00717 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HACLHNLC_00718 4.7e-58 rplQ J Ribosomal protein L17
HACLHNLC_00719 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HACLHNLC_00720 5.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HACLHNLC_00721 2.2e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HACLHNLC_00722 1.1e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HACLHNLC_00723 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HACLHNLC_00724 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HACLHNLC_00725 8.2e-145 ybaJ Q Methyltransferase domain
HACLHNLC_00726 2.7e-82 yizA S Damage-inducible protein DinB
HACLHNLC_00727 4.5e-79 ybaK S Protein of unknown function (DUF2521)
HACLHNLC_00728 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HACLHNLC_00729 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HACLHNLC_00730 1.7e-75 gerD
HACLHNLC_00731 1e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HACLHNLC_00732 1.9e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
HACLHNLC_00733 1.9e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HACLHNLC_00734 1.2e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HACLHNLC_00735 5.9e-29 yazB K transcriptional
HACLHNLC_00736 8.4e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HACLHNLC_00737 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HACLHNLC_00738 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HACLHNLC_00739 3.8e-162 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HACLHNLC_00740 2.3e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HACLHNLC_00741 8.9e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HACLHNLC_00742 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HACLHNLC_00743 3.5e-155 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HACLHNLC_00744 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HACLHNLC_00745 3.1e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HACLHNLC_00746 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HACLHNLC_00747 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HACLHNLC_00748 4.4e-269 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HACLHNLC_00749 6.2e-185 KLT serine threonine protein kinase
HACLHNLC_00750 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
HACLHNLC_00751 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HACLHNLC_00754 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HACLHNLC_00755 2.3e-52 divIC D Septum formation initiator
HACLHNLC_00756 3.8e-103 yabQ S spore cortex biosynthesis protein
HACLHNLC_00757 1.9e-49 yabP S Sporulation protein YabP
HACLHNLC_00758 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HACLHNLC_00759 4.5e-277 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HACLHNLC_00760 5.4e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HACLHNLC_00761 6.2e-91 spoVT K stage V sporulation protein
HACLHNLC_00762 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HACLHNLC_00763 3.7e-40 yabK S Peptide ABC transporter permease
HACLHNLC_00764 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HACLHNLC_00765 1.7e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HACLHNLC_00766 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HACLHNLC_00767 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HACLHNLC_00768 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HACLHNLC_00769 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HACLHNLC_00770 5.5e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HACLHNLC_00771 4.6e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HACLHNLC_00772 2.9e-27 sspF S DNA topological change
HACLHNLC_00773 2.3e-38 veg S protein conserved in bacteria
HACLHNLC_00774 1.9e-145 yabG S peptidase
HACLHNLC_00775 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HACLHNLC_00776 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HACLHNLC_00777 9.1e-232 rpfB GH23 T protein conserved in bacteria
HACLHNLC_00778 6.9e-144 tatD L hydrolase, TatD
HACLHNLC_00779 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HACLHNLC_00780 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HACLHNLC_00781 1.8e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HACLHNLC_00782 1.4e-47 yazA L endonuclease containing a URI domain
HACLHNLC_00783 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HACLHNLC_00784 7.7e-37 yabA L Involved in initiation control of chromosome replication
HACLHNLC_00785 8.8e-145 yaaT S stage 0 sporulation protein
HACLHNLC_00786 8.2e-182 holB 2.7.7.7 L DNA polymerase III
HACLHNLC_00787 1.2e-71 yaaR S protein conserved in bacteria
HACLHNLC_00788 7.5e-55 yaaQ S protein conserved in bacteria
HACLHNLC_00789 1.5e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HACLHNLC_00790 4e-270 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HACLHNLC_00791 5.5e-190 yaaN P Belongs to the TelA family
HACLHNLC_00792 6.6e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HACLHNLC_00793 2.2e-30 csfB S Inhibitor of sigma-G Gin
HACLHNLC_00794 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HACLHNLC_00795 4.9e-125 yhcW 5.4.2.6 S hydrolase
HACLHNLC_00796 2.6e-68 yhcV S COG0517 FOG CBS domain
HACLHNLC_00797 1.3e-69 yhcU S Family of unknown function (DUF5365)
HACLHNLC_00798 1.8e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HACLHNLC_00799 4.4e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HACLHNLC_00800 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
HACLHNLC_00801 3.4e-115 yhcQ M Spore coat protein
HACLHNLC_00802 2.1e-160 yhcP
HACLHNLC_00803 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HACLHNLC_00804 1.2e-48 yhcM
HACLHNLC_00805 1.6e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HACLHNLC_00806 3e-185 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HACLHNLC_00807 2.3e-145 metQ M Belongs to the nlpA lipoprotein family
HACLHNLC_00808 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
HACLHNLC_00809 1.1e-162 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HACLHNLC_00810 3.4e-166 yhcH V ABC transporter, ATP-binding protein
HACLHNLC_00811 6.1e-126 yhcG V ABC transporter, ATP-binding protein
HACLHNLC_00812 2.5e-62 yhcF K Transcriptional regulator
HACLHNLC_00813 1.3e-52
HACLHNLC_00814 3.8e-55 yhcC
HACLHNLC_00815 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
HACLHNLC_00816 6.4e-285 yhcA EGP Major facilitator Superfamily
HACLHNLC_00817 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
HACLHNLC_00818 4.6e-74 yhbI K DNA-binding transcription factor activity
HACLHNLC_00819 2.7e-216 yhbH S Belongs to the UPF0229 family
HACLHNLC_00820 0.0 prkA T Ser protein kinase
HACLHNLC_00822 6.5e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HACLHNLC_00823 8.6e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HACLHNLC_00824 3.9e-108 yhbD K Protein of unknown function (DUF4004)
HACLHNLC_00825 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HACLHNLC_00826 4.8e-176 yhbB S Putative amidase domain
HACLHNLC_00827 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HACLHNLC_00828 1.5e-112 yhzB S B3/4 domain
HACLHNLC_00830 4.8e-23 K Transcriptional regulator
HACLHNLC_00831 1.1e-80 ygaO
HACLHNLC_00832 1.6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HACLHNLC_00833 4.2e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HACLHNLC_00834 8.3e-143 ssuC P ABC transporter (permease)
HACLHNLC_00835 2e-180 ssuA M Sulfonate ABC transporter
HACLHNLC_00836 4.6e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HACLHNLC_00837 1e-185 S Amidohydrolase
HACLHNLC_00838 3.9e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HACLHNLC_00839 4.8e-134 oppF3 E Belongs to the ABC transporter superfamily
HACLHNLC_00840 5.8e-135 oppD3 P Belongs to the ABC transporter superfamily
HACLHNLC_00841 1.7e-125 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACLHNLC_00842 3.1e-141 appB P Binding-protein-dependent transport system inner membrane component
HACLHNLC_00843 4.9e-230 oppA5 E PFAM extracellular solute-binding protein family 5
HACLHNLC_00845 2e-263 ygaK C Berberine and berberine like
HACLHNLC_00846 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HACLHNLC_00847 8.5e-50 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HACLHNLC_00848 1.1e-68 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HACLHNLC_00849 7e-284 C Na+/H+ antiporter family
HACLHNLC_00853 1.6e-08
HACLHNLC_00856 4.5e-28 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_00857 3.1e-189 C Nitroreductase
HACLHNLC_00858 1.9e-132 nrsA Q Thioesterase domain
HACLHNLC_00859 1.1e-284 norB EGP COG0477 Permeases of the major facilitator superfamily
HACLHNLC_00860 2.1e-190 yhcC S Fe-S oxidoreductase
HACLHNLC_00861 1.9e-106 ytqB J Putative rRNA methylase
HACLHNLC_00863 1.1e-144 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
HACLHNLC_00864 2.9e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HACLHNLC_00865 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
HACLHNLC_00866 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HACLHNLC_00867 3.7e-260 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HACLHNLC_00868 0.0 asnB 6.3.5.4 E Asparagine synthase
HACLHNLC_00869 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HACLHNLC_00870 3.7e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HACLHNLC_00871 1.6e-38 ytmB S Protein of unknown function (DUF2584)
HACLHNLC_00872 1.5e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HACLHNLC_00873 9.6e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HACLHNLC_00874 8.3e-145 ytlC P ABC transporter
HACLHNLC_00875 5.8e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HACLHNLC_00876 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HACLHNLC_00877 1.7e-61 ytkC S Bacteriophage holin family
HACLHNLC_00878 1.6e-76 dps P Belongs to the Dps family
HACLHNLC_00880 3.6e-76 ytkA S YtkA-like
HACLHNLC_00881 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HACLHNLC_00882 8.9e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HACLHNLC_00883 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HACLHNLC_00884 1.6e-41 rpmE2 J Ribosomal protein L31
HACLHNLC_00885 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
HACLHNLC_00886 2e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HACLHNLC_00887 2.3e-24 S Domain of Unknown Function (DUF1540)
HACLHNLC_00888 9.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HACLHNLC_00889 1.1e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HACLHNLC_00890 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HACLHNLC_00891 6.5e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HACLHNLC_00892 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HACLHNLC_00893 2.7e-271 menF 5.4.4.2 HQ Isochorismate synthase
HACLHNLC_00894 1.7e-131 dksA T COG1734 DnaK suppressor protein
HACLHNLC_00895 1.1e-75 tspO T membrane
HACLHNLC_00904 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HACLHNLC_00905 3.4e-110 ywbG M effector of murein hydrolase
HACLHNLC_00906 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HACLHNLC_00907 8.2e-152 ywbI K Transcriptional regulator
HACLHNLC_00908 4.8e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HACLHNLC_00909 5.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HACLHNLC_00910 3.7e-243 ywbN P Dyp-type peroxidase family protein
HACLHNLC_00911 1.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HACLHNLC_00912 7.7e-131 S Streptomycin biosynthesis protein StrF
HACLHNLC_00913 3.6e-128 H Methionine biosynthesis protein MetW
HACLHNLC_00915 1.9e-112 ywcC K Bacterial regulatory proteins, tetR family
HACLHNLC_00916 1.7e-61 gtcA S GtrA-like protein
HACLHNLC_00917 1.6e-157 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HACLHNLC_00918 3.5e-296 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HACLHNLC_00919 8.4e-27 ywzA S membrane
HACLHNLC_00920 1.4e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HACLHNLC_00921 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HACLHNLC_00922 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HACLHNLC_00923 9.9e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HACLHNLC_00924 1.1e-37 ywcE S Required for proper spore morphogenesis. Important for spore germination
HACLHNLC_00925 5.3e-79 ysnE K acetyltransferase
HACLHNLC_00926 2.9e-213 rodA D Belongs to the SEDS family
HACLHNLC_00927 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HACLHNLC_00928 2.3e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACLHNLC_00929 0.0 vpr O Belongs to the peptidase S8 family
HACLHNLC_00931 8.3e-151 sacT K transcriptional antiterminator
HACLHNLC_00932 2e-07 sacT K transcriptional antiterminator
HACLHNLC_00933 3.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACLHNLC_00934 3e-281 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
HACLHNLC_00935 9.7e-20 ywdA
HACLHNLC_00936 2.3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HACLHNLC_00937 6.3e-57 pex K Transcriptional regulator PadR-like family
HACLHNLC_00938 3.4e-88 ywdD
HACLHNLC_00940 5e-153 ywdF GT2,GT4 S Glycosyltransferase like family 2
HACLHNLC_00941 1.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HACLHNLC_00942 4.7e-41 ywdI S Family of unknown function (DUF5327)
HACLHNLC_00943 1.7e-230 ywdJ F Xanthine uracil
HACLHNLC_00944 4.2e-46 ywdK S small membrane protein
HACLHNLC_00945 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HACLHNLC_00946 1.7e-142 spsA M Spore Coat
HACLHNLC_00947 1.3e-273 spsB M Capsule polysaccharide biosynthesis protein
HACLHNLC_00948 1.6e-221 spsC E Belongs to the DegT DnrJ EryC1 family
HACLHNLC_00949 1.9e-158 spsD 2.3.1.210 K Spore Coat
HACLHNLC_00950 1.3e-215 spsE 2.5.1.56 M acid synthase
HACLHNLC_00951 1.4e-133 spsF M Spore Coat
HACLHNLC_00952 2.4e-184 spsG M Spore Coat
HACLHNLC_00953 1.2e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HACLHNLC_00954 6e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HACLHNLC_00955 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HACLHNLC_00956 3.5e-87 spsL 5.1.3.13 M Spore Coat
HACLHNLC_00957 6.7e-173 bcrA5 V ABC transporter, ATP-binding protein
HACLHNLC_00958 5.1e-117 S ABC-2 family transporter protein
HACLHNLC_00959 1e-74
HACLHNLC_00960 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACLHNLC_00961 6.6e-157 T PhoQ Sensor
HACLHNLC_00962 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HACLHNLC_00963 1.2e-293 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HACLHNLC_00964 0.0 rocB E arginine degradation protein
HACLHNLC_00965 2.2e-260 lysP E amino acid
HACLHNLC_00966 4.5e-206 tcaB EGP Major facilitator Superfamily
HACLHNLC_00967 4.1e-223 ywfA EGP Major facilitator Superfamily
HACLHNLC_00968 3.3e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HACLHNLC_00969 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HACLHNLC_00970 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACLHNLC_00971 1.1e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HACLHNLC_00972 4.7e-208 bacE EGP Major facilitator Superfamily
HACLHNLC_00973 3.5e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
HACLHNLC_00974 8.2e-140 IQ Enoyl-(Acyl carrier protein) reductase
HACLHNLC_00975 1.1e-146 ywfI C May function as heme-dependent peroxidase
HACLHNLC_00976 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HACLHNLC_00977 1.1e-157 MA20_14895 S Conserved hypothetical protein 698
HACLHNLC_00978 2.3e-162 cysL K Transcriptional regulator
HACLHNLC_00979 2.3e-159 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HACLHNLC_00981 4.5e-174
HACLHNLC_00984 1.3e-168 yhcI S ABC transporter (permease)
HACLHNLC_00985 8.5e-165 V ABC transporter, ATP-binding protein
HACLHNLC_00986 2e-92 S membrane
HACLHNLC_00987 7.4e-52 padR K PadR family transcriptional regulator
HACLHNLC_00988 3e-110 rsfA_1
HACLHNLC_00989 6.9e-36 ywzC S Belongs to the UPF0741 family
HACLHNLC_00990 3.9e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HACLHNLC_00991 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
HACLHNLC_00992 3e-246 yhdG_1 E C-terminus of AA_permease
HACLHNLC_00993 8e-70 ywhA K Transcriptional regulator
HACLHNLC_00994 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HACLHNLC_00995 1.2e-117 ywhC S Peptidase family M50
HACLHNLC_00996 1.4e-95 ywhD S YwhD family
HACLHNLC_00997 5.7e-79
HACLHNLC_00998 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HACLHNLC_00999 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HACLHNLC_01000 3.5e-168 speB 3.5.3.11 E Belongs to the arginase family
HACLHNLC_01003 5.8e-75 CP Membrane
HACLHNLC_01005 7.5e-28 S Domain of unknown function (DUF4177)
HACLHNLC_01006 5e-33
HACLHNLC_01007 9.7e-29 ydcG K sequence-specific DNA binding
HACLHNLC_01009 1.4e-76 S aspartate phosphatase
HACLHNLC_01010 1.3e-209 ywhK CO amine dehydrogenase activity
HACLHNLC_01011 1.8e-227 ywhL CO amine dehydrogenase activity
HACLHNLC_01013 8.8e-72 ywiB S protein conserved in bacteria
HACLHNLC_01014 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HACLHNLC_01015 2.2e-213 narK P COG2223 Nitrate nitrite transporter
HACLHNLC_01016 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
HACLHNLC_01017 1.3e-139 ywiC S YwiC-like protein
HACLHNLC_01018 2e-85 arfM T cyclic nucleotide binding
HACLHNLC_01019 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HACLHNLC_01020 3.4e-293 narH 1.7.5.1 C Nitrate reductase, beta
HACLHNLC_01021 1.3e-96 narJ 1.7.5.1 C nitrate reductase
HACLHNLC_01022 1.2e-123 narI 1.7.5.1 C nitrate reductase, gamma
HACLHNLC_01023 8.9e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HACLHNLC_01024 9.9e-288 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HACLHNLC_01025 0.0 ywjA V ABC transporter
HACLHNLC_01026 4.2e-43 ywjC
HACLHNLC_01027 9.2e-178 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HACLHNLC_01028 9.2e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HACLHNLC_01029 0.0 fadF C COG0247 Fe-S oxidoreductase
HACLHNLC_01030 8.3e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HACLHNLC_01031 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HACLHNLC_01032 4.2e-92 ywjG S Domain of unknown function (DUF2529)
HACLHNLC_01033 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
HACLHNLC_01034 2.1e-157 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HACLHNLC_01035 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HACLHNLC_01036 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HACLHNLC_01037 2.1e-174 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HACLHNLC_01038 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HACLHNLC_01039 1.1e-32 rpmE J Binds the 23S rRNA
HACLHNLC_01040 1.4e-104 tdk 2.7.1.21 F thymidine kinase
HACLHNLC_01041 0.0 sfcA 1.1.1.38 C malic enzyme
HACLHNLC_01042 3.6e-158 ywkB S Membrane transport protein
HACLHNLC_01043 4.4e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HACLHNLC_01044 5.8e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HACLHNLC_01045 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HACLHNLC_01046 1.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HACLHNLC_01047 1.2e-08 ywlA S Uncharacterised protein family (UPF0715)
HACLHNLC_01048 6.7e-60 ywlA S Uncharacterised protein family (UPF0715)
HACLHNLC_01049 8.9e-119 spoIIR S stage II sporulation protein R
HACLHNLC_01050 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HACLHNLC_01051 1.1e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HACLHNLC_01052 4.5e-84 mntP P Probably functions as a manganese efflux pump
HACLHNLC_01053 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HACLHNLC_01054 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HACLHNLC_01055 6.5e-96 ywlG S Belongs to the UPF0340 family
HACLHNLC_01056 2.5e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HACLHNLC_01057 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HACLHNLC_01058 2.1e-61 atpI S ATP synthase
HACLHNLC_01059 2.1e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HACLHNLC_01060 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HACLHNLC_01061 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HACLHNLC_01062 1e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HACLHNLC_01063 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HACLHNLC_01064 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HACLHNLC_01065 7e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HACLHNLC_01066 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HACLHNLC_01067 2.3e-89 ywmA
HACLHNLC_01068 1.3e-32 ywzB S membrane
HACLHNLC_01069 2.2e-134 ywmB S TATA-box binding
HACLHNLC_01070 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HACLHNLC_01071 3.3e-189 spoIID D Stage II sporulation protein D
HACLHNLC_01072 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HACLHNLC_01073 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HACLHNLC_01075 2.2e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HACLHNLC_01076 5.9e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HACLHNLC_01077 1.9e-94 S response regulator aspartate phosphatase
HACLHNLC_01078 3.6e-82 ywmF S Peptidase M50
HACLHNLC_01079 7.4e-10 csbD K CsbD-like
HACLHNLC_01080 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HACLHNLC_01081 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HACLHNLC_01082 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HACLHNLC_01083 2.1e-67 ywnA K Transcriptional regulator
HACLHNLC_01084 1.7e-119 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HACLHNLC_01085 2.8e-53 ywnC S Family of unknown function (DUF5362)
HACLHNLC_01086 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HACLHNLC_01087 2.7e-68 ywnF S Family of unknown function (DUF5392)
HACLHNLC_01088 1.2e-10 ywnC S Family of unknown function (DUF5362)
HACLHNLC_01089 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HACLHNLC_01090 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HACLHNLC_01091 1.1e-71 ywnJ S VanZ like family
HACLHNLC_01092 3.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HACLHNLC_01093 4.9e-210 ftsW D Belongs to the SEDS family
HACLHNLC_01094 2e-58 nrgB K Belongs to the P(II) protein family
HACLHNLC_01095 7.1e-228 amt P Ammonium transporter
HACLHNLC_01096 2.4e-101 phzA Q Isochorismatase family
HACLHNLC_01097 3.6e-244 ywoD EGP Major facilitator superfamily
HACLHNLC_01098 2.1e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HACLHNLC_01099 1.1e-212 ywoG EGP Major facilitator Superfamily
HACLHNLC_01100 8.5e-72 ywoH K transcriptional
HACLHNLC_01101 1.8e-44 spoIIID K Stage III sporulation protein D
HACLHNLC_01102 2.7e-180 mbl D Rod shape-determining protein
HACLHNLC_01103 3.2e-128 flhO N flagellar basal body
HACLHNLC_01104 5.3e-142 flhP N flagellar basal body
HACLHNLC_01105 4.7e-199 S aspartate phosphatase
HACLHNLC_01106 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HACLHNLC_01107 9e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HACLHNLC_01108 3.9e-69 ywpF S YwpF-like protein
HACLHNLC_01109 4e-62 ywpG
HACLHNLC_01110 7.5e-58 ssbB L Single-stranded DNA-binding protein
HACLHNLC_01111 8.9e-137 glcR K DeoR C terminal sensor domain
HACLHNLC_01112 2.3e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HACLHNLC_01113 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HACLHNLC_01114 6e-307 ywqB S SWIM zinc finger
HACLHNLC_01115 1.3e-14
HACLHNLC_01116 1.7e-110 ywqC M biosynthesis protein
HACLHNLC_01117 4.8e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HACLHNLC_01118 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HACLHNLC_01119 3.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HACLHNLC_01120 1e-150 ywqG S Domain of unknown function (DUF1963)
HACLHNLC_01122 1.1e-21 S Domain of unknown function (DUF5082)
HACLHNLC_01123 3.6e-36 ywqI S Family of unknown function (DUF5344)
HACLHNLC_01124 1.4e-257 ywqJ S Pre-toxin TG
HACLHNLC_01125 1e-63
HACLHNLC_01126 1.1e-94
HACLHNLC_01127 6.5e-136 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HACLHNLC_01128 3.8e-88 ywrA P COG2059 Chromate transport protein ChrA
HACLHNLC_01129 2.3e-102 ywrB P Chromate transporter
HACLHNLC_01130 1.1e-83 ywrC K Transcriptional regulator
HACLHNLC_01131 1.4e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HACLHNLC_01132 8e-07 S Domain of unknown function (DUF4181)
HACLHNLC_01133 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HACLHNLC_01134 2e-09
HACLHNLC_01135 1e-212 cotH M Spore Coat
HACLHNLC_01136 7e-132 cotB
HACLHNLC_01137 4.4e-126 ywrJ
HACLHNLC_01138 2.1e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HACLHNLC_01139 9e-167 alsR K LysR substrate binding domain
HACLHNLC_01140 1.2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HACLHNLC_01141 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HACLHNLC_01142 2.9e-96 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HACLHNLC_01143 1.5e-89 batE T Sh3 type 3 domain protein
HACLHNLC_01144 5.7e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HACLHNLC_01145 1.9e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HACLHNLC_01146 4.2e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HACLHNLC_01147 4.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HACLHNLC_01148 3e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HACLHNLC_01149 4.2e-178 rbsR K transcriptional
HACLHNLC_01150 4.8e-202 gerKC S Spore germination B3/ GerAC like, C-terminal
HACLHNLC_01151 1.5e-192 gerKB E Spore germination protein
HACLHNLC_01152 1.2e-197 gerKA EG Spore germination protein
HACLHNLC_01153 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HACLHNLC_01154 2.3e-70 pgsC S biosynthesis protein
HACLHNLC_01155 1.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HACLHNLC_01156 1.1e-19 ywtC
HACLHNLC_01157 8.3e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HACLHNLC_01158 2.6e-36 yttA 2.7.13.3 S Pfam Transposase IS66
HACLHNLC_01159 1e-156 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HACLHNLC_01160 1.9e-178 ywtF K Transcriptional regulator
HACLHNLC_01161 3.2e-248 ywtG EGP Major facilitator Superfamily
HACLHNLC_01162 1.6e-263 GT2,GT4 J Glycosyl transferase family 2
HACLHNLC_01163 7.9e-213 gerAC S Spore germination protein
HACLHNLC_01164 6.4e-199 gerBB E Spore germination protein
HACLHNLC_01165 4.6e-266 gerBA EG Spore germination protein
HACLHNLC_01166 6.7e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HACLHNLC_01167 8.3e-229 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HACLHNLC_01168 1.2e-219 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HACLHNLC_01169 2.6e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HACLHNLC_01170 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HACLHNLC_01171 1.2e-288 M Glycosyltransferase like family 2
HACLHNLC_01172 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HACLHNLC_01173 2.8e-151 tagG GM Transport permease protein
HACLHNLC_01174 6.4e-282 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HACLHNLC_01175 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HACLHNLC_01176 2e-211 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HACLHNLC_01177 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HACLHNLC_01178 1.7e-48
HACLHNLC_01179 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HACLHNLC_01180 1e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HACLHNLC_01181 4e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HACLHNLC_01182 1.1e-256 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HACLHNLC_01183 1.4e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HACLHNLC_01184 1.5e-250 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HACLHNLC_01185 5e-257 tuaE M Teichuronic acid biosynthesis protein
HACLHNLC_01186 4.6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
HACLHNLC_01187 5.8e-143 tuaG GT2 M Glycosyltransferase like family 2
HACLHNLC_01188 2.6e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HACLHNLC_01189 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HACLHNLC_01190 1.5e-172 yvhJ K Transcriptional regulator
HACLHNLC_01191 2.2e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HACLHNLC_01192 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HACLHNLC_01193 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACLHNLC_01194 1.4e-158 degV S protein conserved in bacteria
HACLHNLC_01195 2.7e-255 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HACLHNLC_01196 1.7e-42 comFB S Late competence development protein ComFB
HACLHNLC_01197 4.1e-78 comFC S Phosphoribosyl transferase domain
HACLHNLC_01198 1.4e-74 yvyF S flagellar protein
HACLHNLC_01199 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
HACLHNLC_01200 7.6e-80 flgN NOU FlgN protein
HACLHNLC_01201 1.1e-273 flgK N flagellar hook-associated protein
HACLHNLC_01202 2.3e-162 flgL N Belongs to the bacterial flagellin family
HACLHNLC_01203 1.4e-80 yviE
HACLHNLC_01204 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HACLHNLC_01205 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HACLHNLC_01206 2.1e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HACLHNLC_01207 4.8e-261 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HACLHNLC_01208 8.8e-66 fliS N flagellar protein FliS
HACLHNLC_01209 4.1e-11 fliT S bacterial-type flagellum organization
HACLHNLC_01210 6.8e-68
HACLHNLC_01211 4.8e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HACLHNLC_01212 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HACLHNLC_01213 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HACLHNLC_01214 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HACLHNLC_01215 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
HACLHNLC_01216 1e-122 ftsE D cell division ATP-binding protein FtsE
HACLHNLC_01217 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HACLHNLC_01218 2.6e-46 L Molecular Function DNA binding, Biological Process DNA recombination
HACLHNLC_01219 2.8e-41 L transposase activity
HACLHNLC_01220 2.9e-225 ywoF P Right handed beta helix region
HACLHNLC_01221 3.2e-256 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HACLHNLC_01222 1.5e-55 swrA S Swarming motility protein
HACLHNLC_01223 9.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HACLHNLC_01224 1e-183 S Psort location CytoplasmicMembrane, score
HACLHNLC_01226 1.7e-26 bacT Q Thioesterase domain
HACLHNLC_01227 3e-227 yvkA EGP Major facilitator Superfamily
HACLHNLC_01228 2.4e-110 yvkB K Transcriptional regulator
HACLHNLC_01229 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HACLHNLC_01230 7.6e-33 csbA S protein conserved in bacteria
HACLHNLC_01231 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HACLHNLC_01232 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HACLHNLC_01233 1.5e-37 yvkN
HACLHNLC_01234 4e-48 yvlA
HACLHNLC_01235 3.2e-166 yvlB S Putative adhesin
HACLHNLC_01236 9.6e-26 pspB KT PspC domain
HACLHNLC_01237 3.9e-41 yvlD S Membrane
HACLHNLC_01238 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HACLHNLC_01239 8.1e-105 yxaF K Transcriptional regulator
HACLHNLC_01240 1.5e-132 yvoA K transcriptional
HACLHNLC_01241 6.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HACLHNLC_01242 6.1e-224 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HACLHNLC_01243 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HACLHNLC_01244 1.4e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HACLHNLC_01245 1.1e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HACLHNLC_01246 4.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HACLHNLC_01247 1.8e-138 yvpB NU protein conserved in bacteria
HACLHNLC_01248 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HACLHNLC_01249 1.3e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HACLHNLC_01250 2.1e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HACLHNLC_01251 2e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HACLHNLC_01252 9.6e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HACLHNLC_01253 2.2e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HACLHNLC_01254 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HACLHNLC_01255 2.1e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HACLHNLC_01256 0.0 msbA2 3.6.3.44 V ABC transporter
HACLHNLC_01257 1.2e-120 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACLHNLC_01258 1.4e-190 sasA T Histidine kinase
HACLHNLC_01259 4.2e-275 S COG0457 FOG TPR repeat
HACLHNLC_01260 1.3e-124 usp CBM50 M protein conserved in bacteria
HACLHNLC_01261 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HACLHNLC_01262 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HACLHNLC_01263 1.1e-166 rapZ S Displays ATPase and GTPase activities
HACLHNLC_01264 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HACLHNLC_01265 3.1e-170 whiA K May be required for sporulation
HACLHNLC_01266 4.7e-36 crh G Phosphocarrier protein Chr
HACLHNLC_01267 1.3e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HACLHNLC_01268 4.6e-79 M Ribonuclease
HACLHNLC_01269 5e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HACLHNLC_01270 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HACLHNLC_01271 9.5e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HACLHNLC_01272 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HACLHNLC_01273 2.1e-105 yvdD 3.2.2.10 S Belongs to the LOG family
HACLHNLC_01274 3.4e-250 EGP Sugar (and other) transporter
HACLHNLC_01275 5.5e-214 yraM S PrpF protein
HACLHNLC_01276 6.7e-164 yraN K Transcriptional regulator
HACLHNLC_01277 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HACLHNLC_01278 1.3e-184 scrR K transcriptional
HACLHNLC_01279 8e-219 rafB P LacY proton/sugar symporter
HACLHNLC_01280 8.2e-295 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
HACLHNLC_01282 3.1e-34
HACLHNLC_01283 1.2e-236 I Pfam Lipase (class 3)
HACLHNLC_01284 1.3e-15 S Protein of unknown function (DUF1433)
HACLHNLC_01285 3.2e-25 S Protein of unknown function (DUF1433)
HACLHNLC_01286 1.2e-39 I Pfam Lipase (class 3)
HACLHNLC_01287 6.5e-38 S Protein of unknown function (DUF1433)
HACLHNLC_01288 7e-17 S Protein of unknown function (DUF1433)
HACLHNLC_01289 5.5e-94 padC Q Phenolic acid decarboxylase
HACLHNLC_01290 1.2e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HACLHNLC_01291 1.3e-111 yyaS S Membrane
HACLHNLC_01292 5.2e-98 ywjB H RibD C-terminal domain
HACLHNLC_01294 4.2e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HACLHNLC_01295 5.1e-78 slr K transcriptional
HACLHNLC_01296 8.4e-120 ywqC M biosynthesis protein
HACLHNLC_01297 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HACLHNLC_01298 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HACLHNLC_01299 1.3e-218 epsD GT4 M Glycosyl transferase 4-like
HACLHNLC_01300 3.1e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HACLHNLC_01301 5.5e-214 epsF GT4 M Glycosyl transferases group 1
HACLHNLC_01302 3.5e-205 epsG S EpsG family
HACLHNLC_01303 3.4e-194 epsH GT2 S Glycosyltransferase like family 2
HACLHNLC_01304 5.4e-203 epsI GM pyruvyl transferase
HACLHNLC_01305 1.8e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HACLHNLC_01306 7e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HACLHNLC_01307 1.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HACLHNLC_01308 1.6e-53 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HACLHNLC_01309 9e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HACLHNLC_01310 6e-185 yvfF GM Exopolysaccharide biosynthesis protein
HACLHNLC_01311 2.7e-32 yvfG S YvfG protein
HACLHNLC_01312 9.1e-245 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HACLHNLC_01313 1.9e-303 yvfH C L-lactate permease
HACLHNLC_01314 6.6e-120 yvfI K COG2186 Transcriptional regulators
HACLHNLC_01315 2.9e-221 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HACLHNLC_01316 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HACLHNLC_01317 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HACLHNLC_01318 1.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HACLHNLC_01319 2.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
HACLHNLC_01320 2.1e-296 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
HACLHNLC_01321 5e-151 ybbH_1 K RpiR family transcriptional regulator
HACLHNLC_01322 5.1e-167 3.1.3.104 S hydrolases of the HAD superfamily
HACLHNLC_01323 1.3e-114 yyaS S Membrane
HACLHNLC_01324 4e-181 purR7 5.1.1.1 K Transcriptional regulator
HACLHNLC_01325 1.9e-258
HACLHNLC_01326 5e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HACLHNLC_01327 1.7e-157 yvbV EG EamA-like transporter family
HACLHNLC_01328 1.5e-155 yvbU K Transcriptional regulator
HACLHNLC_01330 3.2e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACLHNLC_01331 3.2e-203 araR K transcriptional
HACLHNLC_01332 1.3e-252 araE EGP Major facilitator Superfamily
HACLHNLC_01334 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HACLHNLC_01335 4.8e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HACLHNLC_01336 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HACLHNLC_01337 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HACLHNLC_01338 2.8e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HACLHNLC_01339 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HACLHNLC_01340 9.8e-236 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HACLHNLC_01341 1.8e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HACLHNLC_01342 1.8e-217 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HACLHNLC_01343 1.4e-170 5.1.3.2 M GDP-mannose 4,6 dehydratase
HACLHNLC_01344 1.4e-231 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HACLHNLC_01345 3.5e-147 M Protein involved in cellulose biosynthesis
HACLHNLC_01346 9.6e-143 C WbqC-like protein family
HACLHNLC_01347 3.7e-125 S GlcNAc-PI de-N-acetylase
HACLHNLC_01348 7.9e-179
HACLHNLC_01349 6e-214 EGP Major facilitator Superfamily
HACLHNLC_01350 2.5e-80 yvbK 3.1.3.25 K acetyltransferase
HACLHNLC_01351 0.0 tcaA S response to antibiotic
HACLHNLC_01352 3.2e-119 exoY M Membrane
HACLHNLC_01353 5.2e-105 yvbG U UPF0056 membrane protein
HACLHNLC_01354 7.1e-98 yvbF K Belongs to the GbsR family
HACLHNLC_01355 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HACLHNLC_01356 1e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HACLHNLC_01357 4.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HACLHNLC_01358 6.3e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HACLHNLC_01359 4.3e-76 yvbF K Belongs to the GbsR family
HACLHNLC_01360 6.3e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HACLHNLC_01361 5.4e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HACLHNLC_01362 1.7e-173 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HACLHNLC_01363 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HACLHNLC_01364 4.6e-126 mutF V ABC transporter, ATP-binding protein
HACLHNLC_01365 1e-120 spaE S ABC-2 family transporter protein
HACLHNLC_01366 7.5e-138 mutG S ABC-2 family transporter protein
HACLHNLC_01367 2e-123 K Transcriptional regulatory protein, C terminal
HACLHNLC_01368 9.7e-253 T His Kinase A (phosphoacceptor) domain
HACLHNLC_01369 8.8e-53 yodB K transcriptional
HACLHNLC_01370 1.1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
HACLHNLC_01371 1e-69 K transcriptional
HACLHNLC_01372 6e-35 yvzC K Transcriptional
HACLHNLC_01373 4.8e-24 secG U Preprotein translocase subunit SecG
HACLHNLC_01374 7.4e-143 est 3.1.1.1 S Carboxylesterase
HACLHNLC_01375 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HACLHNLC_01376 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HACLHNLC_01378 2.3e-39 yrdF K ribonuclease inhibitor
HACLHNLC_01379 6.7e-50 yrdF K ribonuclease inhibitor
HACLHNLC_01380 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HACLHNLC_01381 2.6e-158 ytlI K LysR substrate binding domain
HACLHNLC_01382 3e-101 ytmI K Acetyltransferase (GNAT) domain
HACLHNLC_01383 2.7e-130 ytmJ ET Bacterial periplasmic substrate-binding proteins
HACLHNLC_01384 1e-145 tcyK M Bacterial periplasmic substrate-binding proteins
HACLHNLC_01385 7.7e-121 tcyL P Binding-protein-dependent transport system inner membrane component
HACLHNLC_01386 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
HACLHNLC_01387 3.6e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HACLHNLC_01388 6e-180 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACLHNLC_01389 1.5e-46 ytnI O COG0695 Glutaredoxin and related proteins
HACLHNLC_01390 1.2e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACLHNLC_01391 5.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HACLHNLC_01392 1.4e-192 yvaA 1.1.1.371 S Oxidoreductase
HACLHNLC_01393 3.7e-48 csoR S transcriptional
HACLHNLC_01394 9.9e-29 copZ P Heavy-metal-associated domain
HACLHNLC_01395 0.0 copA 3.6.3.54 P P-type ATPase
HACLHNLC_01396 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HACLHNLC_01397 1.2e-102 bdbD O Thioredoxin
HACLHNLC_01398 1e-72 bdbC O Required for disulfide bond formation in some proteins
HACLHNLC_01399 5.2e-142 S Metallo-peptidase family M12
HACLHNLC_01400 3.5e-106 yvgT S membrane
HACLHNLC_01401 0.0 helD 3.6.4.12 L DNA helicase
HACLHNLC_01402 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HACLHNLC_01403 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HACLHNLC_01404 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HACLHNLC_01405 5.4e-86 yvgO
HACLHNLC_01406 5e-156 yvgN S reductase
HACLHNLC_01407 4.7e-197 yfiN V COG0842 ABC-type multidrug transport system, permease component
HACLHNLC_01408 6.1e-194 yfiM V ABC-2 type transporter
HACLHNLC_01409 2.1e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
HACLHNLC_01410 1.3e-63 T Histidine kinase
HACLHNLC_01411 1.7e-85 T Histidine kinase
HACLHNLC_01412 2.8e-114 yfiK K Regulator
HACLHNLC_01413 1e-98 modB P COG4149 ABC-type molybdate transport system, permease component
HACLHNLC_01414 3.7e-140 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HACLHNLC_01415 1.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HACLHNLC_01416 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HACLHNLC_01417 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HACLHNLC_01418 3.6e-14 S Small spore protein J (Spore_SspJ)
HACLHNLC_01419 1.3e-236 yvsH E Arginine ornithine antiporter
HACLHNLC_01420 2e-177 fhuD P ABC transporter
HACLHNLC_01421 2.5e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACLHNLC_01422 4e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACLHNLC_01423 3.1e-147 fhuC 3.6.3.34 HP ABC transporter
HACLHNLC_01424 1.9e-42 L COG2963 Transposase and inactivated derivatives
HACLHNLC_01425 1.2e-124 L Molecular Function DNA binding, Biological Process DNA recombination
HACLHNLC_01426 1.1e-66 yvrL S Regulatory protein YrvL
HACLHNLC_01427 3.5e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
HACLHNLC_01428 1.6e-15 S YvrJ protein family
HACLHNLC_01429 9.9e-103 yvrI K RNA polymerase
HACLHNLC_01430 1.1e-36
HACLHNLC_01431 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACLHNLC_01432 0.0 T PhoQ Sensor
HACLHNLC_01433 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HACLHNLC_01434 5.3e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HACLHNLC_01435 1.1e-167 yvrC P ABC transporter substrate-binding protein
HACLHNLC_01436 8.2e-180 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACLHNLC_01437 1.1e-223 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HACLHNLC_01438 5.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
HACLHNLC_01439 4.8e-227 yvqJ EGP Major facilitator Superfamily
HACLHNLC_01440 3.3e-46 liaI S membrane
HACLHNLC_01441 1.1e-92 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HACLHNLC_01442 4.8e-117 liaG S Putative adhesin
HACLHNLC_01443 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HACLHNLC_01444 2.3e-193 vraS 2.7.13.3 T Histidine kinase
HACLHNLC_01445 9.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACLHNLC_01446 3.1e-201 gerAC S Spore germination B3/ GerAC like, C-terminal
HACLHNLC_01447 1.1e-187 gerAB E Spore germination protein
HACLHNLC_01448 1.3e-257 gerAA EG Spore germination protein
HACLHNLC_01449 6.6e-24 S Protein of unknown function (DUF3970)
HACLHNLC_01450 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HACLHNLC_01451 1e-157 yuxN K Transcriptional regulator
HACLHNLC_01452 1.3e-23
HACLHNLC_01453 6.7e-251 cssS 2.7.13.3 T PhoQ Sensor
HACLHNLC_01454 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACLHNLC_01455 8.5e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HACLHNLC_01456 3.6e-79 dps P Belongs to the Dps family
HACLHNLC_01457 4.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HACLHNLC_01458 0.0 pepF2 E COG1164 Oligoendopeptidase F
HACLHNLC_01459 2.5e-45 S YusW-like protein
HACLHNLC_01460 2.4e-150 yusV 3.6.3.34 HP ABC transporter
HACLHNLC_01461 3.3e-39 yusU S Protein of unknown function (DUF2573)
HACLHNLC_01462 3.9e-190 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HACLHNLC_01463 9.4e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HACLHNLC_01464 8.8e-159 ywbI2 K Transcriptional regulator
HACLHNLC_01465 8.1e-288 yusP P Major facilitator superfamily
HACLHNLC_01466 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
HACLHNLC_01467 1.1e-53 yusN M Coat F domain
HACLHNLC_01468 1.4e-43
HACLHNLC_01469 9e-167 fadM E Proline dehydrogenase
HACLHNLC_01470 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HACLHNLC_01471 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HACLHNLC_01472 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HACLHNLC_01473 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HACLHNLC_01474 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HACLHNLC_01475 3.7e-40 yusG S Protein of unknown function (DUF2553)
HACLHNLC_01476 1.4e-62 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HACLHNLC_01477 1.6e-54 yusE CO Thioredoxin
HACLHNLC_01478 5e-57 yusD S SCP-2 sterol transfer family
HACLHNLC_01479 6.3e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HACLHNLC_01480 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HACLHNLC_01481 2.3e-145 metQ P Belongs to the NlpA lipoprotein family
HACLHNLC_01482 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HACLHNLC_01483 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HACLHNLC_01484 7e-245 sufD O assembly protein SufD
HACLHNLC_01485 1.4e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HACLHNLC_01486 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HACLHNLC_01487 3e-270 sufB O FeS cluster assembly
HACLHNLC_01488 8.6e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HACLHNLC_01489 8.5e-81 yncE S Protein of unknown function (DUF2691)
HACLHNLC_01490 6.3e-128 Q ubiE/COQ5 methyltransferase family
HACLHNLC_01491 1.9e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HACLHNLC_01492 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HACLHNLC_01494 2.3e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HACLHNLC_01495 5.5e-225 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HACLHNLC_01496 1.1e-156 yurN G Binding-protein-dependent transport system inner membrane component
HACLHNLC_01497 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
HACLHNLC_01498 2.4e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HACLHNLC_01499 3.6e-134 yurK K UTRA
HACLHNLC_01500 3.1e-206 msmX P Belongs to the ABC transporter superfamily
HACLHNLC_01501 2.7e-168 bsn L Ribonuclease
HACLHNLC_01502 1.8e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HACLHNLC_01503 1.1e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HACLHNLC_01504 1.7e-213 blt EGP Major facilitator Superfamily
HACLHNLC_01505 2.8e-69
HACLHNLC_01506 5.7e-179 S Aspartate phosphatase response regulator
HACLHNLC_01508 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
HACLHNLC_01509 5e-262 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HACLHNLC_01510 9.8e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
HACLHNLC_01511 8.1e-170 yunF S Protein of unknown function DUF72
HACLHNLC_01512 3.9e-145 yunE S membrane transporter protein
HACLHNLC_01513 4.2e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HACLHNLC_01514 3.6e-129 yunB S Sporulation protein YunB (Spo_YunB)
HACLHNLC_01515 7.1e-194 lytH M Peptidase, M23
HACLHNLC_01516 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HACLHNLC_01517 8.2e-47 yutD S protein conserved in bacteria
HACLHNLC_01518 2.8e-73 yutE S Protein of unknown function DUF86
HACLHNLC_01519 1.4e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HACLHNLC_01520 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HACLHNLC_01521 3.2e-197 yutH S Spore coat protein
HACLHNLC_01522 5.1e-240 hom 1.1.1.3 E homoserine dehydrogenase
HACLHNLC_01523 1.1e-195 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HACLHNLC_01524 7.5e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HACLHNLC_01525 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HACLHNLC_01526 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HACLHNLC_01527 6.7e-56 yuzD S protein conserved in bacteria
HACLHNLC_01528 4.2e-208 yutJ 1.6.99.3 C NADH dehydrogenase
HACLHNLC_01529 2.4e-39 yuzB S Belongs to the UPF0349 family
HACLHNLC_01530 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HACLHNLC_01531 5.7e-163 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HACLHNLC_01532 1.1e-62 erpA S Belongs to the HesB IscA family
HACLHNLC_01533 1.6e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HACLHNLC_01534 3.9e-93 rimJ 2.3.1.128 J Alanine acetyltransferase
HACLHNLC_01536 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
HACLHNLC_01538 3.1e-122 V ABC transporter
HACLHNLC_01539 1.6e-70 CP Membrane
HACLHNLC_01540 4.8e-29
HACLHNLC_01541 1.6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HACLHNLC_01543 1.5e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
HACLHNLC_01544 7.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
HACLHNLC_01545 3.8e-27 yuiB S Putative membrane protein
HACLHNLC_01546 3.5e-117 yuiC S protein conserved in bacteria
HACLHNLC_01547 1.3e-76 yuiD S protein conserved in bacteria
HACLHNLC_01548 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HACLHNLC_01549 1.1e-208 yuiF S antiporter
HACLHNLC_01550 1.1e-101 bioY S Biotin biosynthesis protein
HACLHNLC_01551 7.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
HACLHNLC_01552 4.7e-165 besA S Putative esterase
HACLHNLC_01553 6.6e-134 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HACLHNLC_01554 5.2e-223 entC 5.4.4.2 HQ Isochorismate synthase
HACLHNLC_01555 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HACLHNLC_01556 8.6e-173 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HACLHNLC_01557 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_01558 1.3e-34 mbtH S MbtH-like protein
HACLHNLC_01559 2.4e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HACLHNLC_01560 6.7e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HACLHNLC_01561 1.2e-227 yukF QT Transcriptional regulator
HACLHNLC_01562 3.3e-46 esxA S Belongs to the WXG100 family
HACLHNLC_01563 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
HACLHNLC_01564 2.4e-205 essB S WXG100 protein secretion system (Wss), protein YukC
HACLHNLC_01565 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HACLHNLC_01566 0.0 esaA S type VII secretion protein EsaA
HACLHNLC_01567 6.5e-76 yueC S Family of unknown function (DUF5383)
HACLHNLC_01568 4.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACLHNLC_01569 1.8e-95 yueE S phosphohydrolase
HACLHNLC_01570 2.1e-22 S Protein of unknown function (DUF2642)
HACLHNLC_01571 8.9e-185 yueF S transporter activity
HACLHNLC_01572 3.2e-33 yueG S Spore germination protein gerPA/gerPF
HACLHNLC_01573 2.8e-38 yueH S YueH-like protein
HACLHNLC_01574 7.2e-68 yueI S Protein of unknown function (DUF1694)
HACLHNLC_01575 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
HACLHNLC_01576 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HACLHNLC_01577 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HACLHNLC_01578 2.2e-49 yuzC
HACLHNLC_01580 1.5e-147 comQ H Polyprenyl synthetase
HACLHNLC_01582 0.0 comP 2.7.13.3 T Histidine kinase
HACLHNLC_01583 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACLHNLC_01584 3.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
HACLHNLC_01585 1.1e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HACLHNLC_01586 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HACLHNLC_01587 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HACLHNLC_01588 9.9e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HACLHNLC_01589 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HACLHNLC_01590 9.2e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HACLHNLC_01591 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HACLHNLC_01592 1.8e-12
HACLHNLC_01593 2.7e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HACLHNLC_01594 5.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HACLHNLC_01595 2.8e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HACLHNLC_01596 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HACLHNLC_01597 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
HACLHNLC_01598 1.3e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HACLHNLC_01599 9.3e-74 yufK S Family of unknown function (DUF5366)
HACLHNLC_01600 8.5e-72 yuxK S protein conserved in bacteria
HACLHNLC_01601 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HACLHNLC_01602 7.7e-185 yuxJ EGP Major facilitator Superfamily
HACLHNLC_01603 4.5e-118 kapD L the KinA pathway to sporulation
HACLHNLC_01604 3.1e-68 kapB G Kinase associated protein B
HACLHNLC_01605 5.8e-228 T PhoQ Sensor
HACLHNLC_01606 2.7e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HACLHNLC_01607 1.7e-38 yugE S Domain of unknown function (DUF1871)
HACLHNLC_01608 1.6e-154 yugF I Hydrolase
HACLHNLC_01609 2e-83 alaR K Transcriptional regulator
HACLHNLC_01610 5.5e-209 yugH 2.6.1.1 E Aminotransferase
HACLHNLC_01611 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HACLHNLC_01612 1.8e-34 yuzA S Domain of unknown function (DUF378)
HACLHNLC_01613 3.2e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HACLHNLC_01614 2.8e-229 yugK C Dehydrogenase
HACLHNLC_01615 4.2e-118 ycaC Q Isochorismatase family
HACLHNLC_01616 4.7e-97 S NADPH-dependent FMN reductase
HACLHNLC_01617 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
HACLHNLC_01619 2.2e-72 yugN S YugN-like family
HACLHNLC_01620 1.8e-181 yugO P COG1226 Kef-type K transport systems
HACLHNLC_01621 1.1e-26 mstX S Membrane-integrating protein Mistic
HACLHNLC_01622 4.5e-18
HACLHNLC_01623 8.3e-117 yugP S Zn-dependent protease
HACLHNLC_01624 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HACLHNLC_01625 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HACLHNLC_01626 9.7e-76 yugU S Uncharacterised protein family UPF0047
HACLHNLC_01627 2.5e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HACLHNLC_01628 4.8e-41
HACLHNLC_01629 1.3e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HACLHNLC_01630 1.7e-218 mcpA NT chemotaxis protein
HACLHNLC_01631 1.2e-235 mcpA NT chemotaxis protein
HACLHNLC_01632 9.3e-225 mcpA NT chemotaxis protein
HACLHNLC_01633 2.3e-231 mcpA NT chemotaxis protein
HACLHNLC_01634 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HACLHNLC_01635 1.4e-184 ygjR S Oxidoreductase
HACLHNLC_01636 7.6e-195 yubA S transporter activity
HACLHNLC_01637 4e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HACLHNLC_01639 4.6e-33 L Belongs to the 'phage' integrase family
HACLHNLC_01640 1.4e-36 V Restriction endonuclease
HACLHNLC_01643 6e-11 K Helix-turn-helix domain
HACLHNLC_01644 5e-18
HACLHNLC_01646 6.5e-183 S Aspartate phosphatase response regulator
HACLHNLC_01647 5.7e-15
HACLHNLC_01649 8.8e-10 yjcN
HACLHNLC_01650 3.6e-122 G Cupin
HACLHNLC_01651 4.5e-219 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HACLHNLC_01652 4.3e-147 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HACLHNLC_01653 9.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
HACLHNLC_01654 2.1e-94 yuaB
HACLHNLC_01655 6e-97 yuaC K Belongs to the GbsR family
HACLHNLC_01656 9.4e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HACLHNLC_01657 2.1e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
HACLHNLC_01658 2.5e-109 yuaD S MOSC domain
HACLHNLC_01659 4.3e-83 yuaE S DinB superfamily
HACLHNLC_01660 1.5e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HACLHNLC_01661 2.1e-176 yuaG 3.4.21.72 S protein conserved in bacteria
HACLHNLC_01662 1.3e-97 thiT S Thiamine transporter protein (Thia_YuaJ)
HACLHNLC_01663 5.5e-130 IQ reductase
HACLHNLC_01664 2e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HACLHNLC_01667 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HACLHNLC_01668 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
HACLHNLC_01669 4.1e-30 S GlpM protein
HACLHNLC_01670 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HACLHNLC_01671 1.3e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HACLHNLC_01672 6.5e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HACLHNLC_01673 2.5e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HACLHNLC_01674 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HACLHNLC_01675 9.5e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HACLHNLC_01676 3.1e-25 yqzJ
HACLHNLC_01677 7.8e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HACLHNLC_01678 1.4e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HACLHNLC_01679 4.5e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HACLHNLC_01680 1.9e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HACLHNLC_01682 4.8e-96 yqjB S protein conserved in bacteria
HACLHNLC_01683 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
HACLHNLC_01684 1.7e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HACLHNLC_01685 1.3e-88 artQ E COG0765 ABC-type amino acid transport system, permease component
HACLHNLC_01686 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
HACLHNLC_01687 8.1e-82 yfiV K transcriptional
HACLHNLC_01688 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HACLHNLC_01689 9.7e-166 yfhB 5.3.3.17 S PhzF family
HACLHNLC_01690 2.2e-105 yfhC C nitroreductase
HACLHNLC_01691 2.1e-25 yfhD S YfhD-like protein
HACLHNLC_01693 6.2e-12 yfhF S nucleoside-diphosphate sugar epimerase
HACLHNLC_01694 3e-134 yfhF S nucleoside-diphosphate sugar epimerase
HACLHNLC_01695 1.8e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
HACLHNLC_01696 8.8e-53 yfhH S Protein of unknown function (DUF1811)
HACLHNLC_01697 1.5e-206 yfhI EGP Major facilitator Superfamily
HACLHNLC_01699 1.7e-165 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HACLHNLC_01700 2.2e-44 yfhJ S WVELL protein
HACLHNLC_01701 1.6e-94 batE T Bacterial SH3 domain homologues
HACLHNLC_01702 5.7e-34 yfhL S SdpI/YhfL protein family
HACLHNLC_01703 4.1e-169 yfhM S Alpha/beta hydrolase family
HACLHNLC_01704 3e-184 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HACLHNLC_01705 0.0 yfhO S Bacterial membrane protein YfhO
HACLHNLC_01706 1e-184 yfhP S membrane-bound metal-dependent
HACLHNLC_01707 1.4e-209 mutY L A G-specific
HACLHNLC_01708 8.2e-37 yfhS
HACLHNLC_01709 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACLHNLC_01711 1.5e-37 ygaB S YgaB-like protein
HACLHNLC_01712 2.2e-104 ygaC J Belongs to the UPF0374 family
HACLHNLC_01713 2.6e-300 ygaD V ABC transporter
HACLHNLC_01714 1.6e-178 ygaE S Membrane
HACLHNLC_01715 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HACLHNLC_01716 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
HACLHNLC_01717 1.8e-80 perR P Belongs to the Fur family
HACLHNLC_01718 1.5e-56 ygzB S UPF0295 protein
HACLHNLC_01719 5.3e-164 ygxA S Nucleotidyltransferase-like
HACLHNLC_01720 5.8e-225 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HACLHNLC_01721 3.9e-156 K Helix-turn-helix XRE-family like proteins
HACLHNLC_01722 2.2e-123 ydhB S membrane transporter protein
HACLHNLC_01723 5.9e-82 bltD 2.3.1.57 K FR47-like protein
HACLHNLC_01724 2.9e-148 bltR K helix_turn_helix, mercury resistance
HACLHNLC_01725 2.8e-149 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HACLHNLC_01726 1.9e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HACLHNLC_01727 2e-146 ycgJ_1 Q ubiE/COQ5 methyltransferase family
HACLHNLC_01728 1e-70 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HACLHNLC_01731 4.7e-22 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HACLHNLC_01732 8.1e-120 ydhC K FCD
HACLHNLC_01733 1.4e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HACLHNLC_01736 4.8e-265 pbpE V Beta-lactamase
HACLHNLC_01738 2.5e-98 ydhK M Protein of unknown function (DUF1541)
HACLHNLC_01739 1.5e-195 pbuE EGP Major facilitator Superfamily
HACLHNLC_01740 1.9e-132 ydhQ K UTRA
HACLHNLC_01741 2.6e-118 K FCD
HACLHNLC_01742 6.9e-215 yeaN P COG2807 Cyanate permease
HACLHNLC_01743 2.6e-49 sugE P Small Multidrug Resistance protein
HACLHNLC_01744 2.3e-51 ykkC P Small Multidrug Resistance protein
HACLHNLC_01745 5.3e-104 yvdT K Transcriptional regulator
HACLHNLC_01746 3.5e-296 yveA E amino acid
HACLHNLC_01747 3.2e-166 ydhU P Catalase
HACLHNLC_01748 1e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HACLHNLC_01749 8.1e-185 yhfP 1.1.1.1 C Quinone oxidoreductase
HACLHNLC_01750 7e-251 iolT EGP Major facilitator Superfamily
HACLHNLC_01753 0.0 Q Polyketide synthase of type I
HACLHNLC_01754 0.0 1.1.1.320 Q Polyketide synthase of type I
HACLHNLC_01755 0.0 pksJ Q Polyketide synthase of type I
HACLHNLC_01756 1.7e-75 yqiW S Belongs to the UPF0403 family
HACLHNLC_01757 1.3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HACLHNLC_01758 3.6e-190 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HACLHNLC_01759 2.3e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HACLHNLC_01760 8.6e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HACLHNLC_01761 1e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HACLHNLC_01762 7.5e-208 buk 2.7.2.7 C Belongs to the acetokinase family
HACLHNLC_01763 2e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HACLHNLC_01764 9.5e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HACLHNLC_01765 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HACLHNLC_01766 3.2e-34 yqzF S Protein of unknown function (DUF2627)
HACLHNLC_01767 4.8e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HACLHNLC_01768 4.4e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HACLHNLC_01769 2.4e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HACLHNLC_01770 8.5e-207 mmgC I acyl-CoA dehydrogenase
HACLHNLC_01771 1.4e-153 hbdA 1.1.1.157 I Dehydrogenase
HACLHNLC_01772 1.8e-212 mmgA 2.3.1.9 I Belongs to the thiolase family
HACLHNLC_01773 2.5e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HACLHNLC_01774 1.4e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HACLHNLC_01775 2.5e-17
HACLHNLC_01776 1.5e-101 ytaF P Probably functions as a manganese efflux pump
HACLHNLC_01777 1.2e-112 K Protein of unknown function (DUF1232)
HACLHNLC_01778 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
HACLHNLC_01779 3.6e-32 yaaL S Protein of unknown function (DUF2508)
HACLHNLC_01780 8.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HACLHNLC_01781 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HACLHNLC_01782 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HACLHNLC_01783 7.8e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HACLHNLC_01784 9.8e-100 yaaI Q COG1335 Amidases related to nicotinamidase
HACLHNLC_01785 2e-212 yaaH M Glycoside Hydrolase Family
HACLHNLC_01786 1.2e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HACLHNLC_01787 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HACLHNLC_01788 1.3e-09
HACLHNLC_01789 1.8e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HACLHNLC_01790 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HACLHNLC_01791 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HACLHNLC_01792 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HACLHNLC_01793 1.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HACLHNLC_01794 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HACLHNLC_01795 1.5e-183 yaaC S YaaC-like Protein
HACLHNLC_01796 1.1e-197 L COG3666 Transposase and inactivated derivatives
HACLHNLC_01797 3.4e-39 S COG NOG14552 non supervised orthologous group
HACLHNLC_01798 8.4e-54 L COG2963 Transposase and inactivated derivatives
HACLHNLC_01799 7.6e-109 ymaB S MutT family
HACLHNLC_01800 1.3e-187 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HACLHNLC_01801 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HACLHNLC_01802 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HACLHNLC_01803 1.8e-20 ymzA
HACLHNLC_01804 2.2e-44
HACLHNLC_01805 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HACLHNLC_01806 3.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HACLHNLC_01807 1.4e-47 ymaF S YmaF family
HACLHNLC_01809 3.1e-48 ebrA P Small Multidrug Resistance protein
HACLHNLC_01810 5.2e-54 ebrB P Small Multidrug Resistance protein
HACLHNLC_01811 3.9e-78 ymaD O redox protein, regulator of disulfide bond formation
HACLHNLC_01812 6e-126 ymaC S Replication protein
HACLHNLC_01814 1.1e-253 aprX O Belongs to the peptidase S8 family
HACLHNLC_01815 1.4e-62 ymzB
HACLHNLC_01816 9.4e-119 yoaK S Membrane
HACLHNLC_01817 4.1e-77 nucB M Deoxyribonuclease NucA/NucB
HACLHNLC_01818 8.1e-232 cypA C Cytochrome P450
HACLHNLC_01819 0.0 pks13 HQ Beta-ketoacyl synthase
HACLHNLC_01820 0.0 dhbF IQ polyketide synthase
HACLHNLC_01821 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
HACLHNLC_01822 0.0 Q Polyketide synthase of type I
HACLHNLC_01823 0.0 rhiB IQ polyketide synthase
HACLHNLC_01824 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HACLHNLC_01825 4.1e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
HACLHNLC_01826 6.7e-245 pksG 2.3.3.10 I synthase
HACLHNLC_01827 6.5e-35 acpK IQ Phosphopantetheine attachment site
HACLHNLC_01828 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HACLHNLC_01829 3.9e-184 pksD Q Acyl transferase domain
HACLHNLC_01830 7e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HACLHNLC_01831 1.3e-128 pksB 3.1.2.6 S Polyketide biosynthesis
HACLHNLC_01833 9.1e-31
HACLHNLC_01834 3.4e-41 L Belongs to the 'phage' integrase family
HACLHNLC_01835 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HACLHNLC_01836 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HACLHNLC_01837 1.7e-88 cotE S Spore coat protein
HACLHNLC_01838 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HACLHNLC_01839 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HACLHNLC_01840 3.9e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HACLHNLC_01841 1.9e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HACLHNLC_01842 1.2e-36 spoVS S Stage V sporulation protein S
HACLHNLC_01843 4.9e-153 ymdB S protein conserved in bacteria
HACLHNLC_01844 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
HACLHNLC_01845 8.9e-183 pbpX V Beta-lactamase
HACLHNLC_01846 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HACLHNLC_01847 1.7e-232 cinA 3.5.1.42 S Belongs to the CinA family
HACLHNLC_01848 1.1e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HACLHNLC_01849 4.2e-124 ymfM S protein conserved in bacteria
HACLHNLC_01850 3.5e-143 ymfK S Protein of unknown function (DUF3388)
HACLHNLC_01851 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
HACLHNLC_01852 1.3e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HACLHNLC_01853 7.1e-242 ymfH S zinc protease
HACLHNLC_01854 2.6e-236 ymfF S Peptidase M16
HACLHNLC_01855 0.0 ydgH S drug exporters of the RND superfamily
HACLHNLC_01856 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
HACLHNLC_01857 1.1e-229 ymfD EGP Major facilitator Superfamily
HACLHNLC_01858 1.8e-133 ymfC K Transcriptional regulator
HACLHNLC_01859 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HACLHNLC_01860 6.3e-31 S YlzJ-like protein
HACLHNLC_01861 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HACLHNLC_01862 5.7e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HACLHNLC_01863 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HACLHNLC_01864 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HACLHNLC_01865 1.9e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HACLHNLC_01866 9.8e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HACLHNLC_01867 6.1e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HACLHNLC_01868 2.6e-42 ymxH S YlmC YmxH family
HACLHNLC_01869 3e-234 pepR S Belongs to the peptidase M16 family
HACLHNLC_01870 4e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HACLHNLC_01871 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HACLHNLC_01872 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HACLHNLC_01873 3.5e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HACLHNLC_01874 5.2e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HACLHNLC_01875 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HACLHNLC_01876 3.9e-44 ylxP S protein conserved in bacteria
HACLHNLC_01877 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HACLHNLC_01878 4e-47 ylxQ J ribosomal protein
HACLHNLC_01879 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
HACLHNLC_01880 5.4e-206 nusA K Participates in both transcription termination and antitermination
HACLHNLC_01881 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
HACLHNLC_01882 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HACLHNLC_01883 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HACLHNLC_01884 1.5e-233 rasP M zinc metalloprotease
HACLHNLC_01885 7.3e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HACLHNLC_01886 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
HACLHNLC_01887 2.2e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HACLHNLC_01888 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HACLHNLC_01889 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HACLHNLC_01890 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HACLHNLC_01891 1.4e-130 rpsB J Belongs to the universal ribosomal protein uS2 family
HACLHNLC_01892 2.5e-51 ylxL
HACLHNLC_01893 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACLHNLC_01894 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HACLHNLC_01895 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HACLHNLC_01896 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
HACLHNLC_01897 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HACLHNLC_01898 8.6e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HACLHNLC_01899 2.7e-155 flhG D Belongs to the ParA family
HACLHNLC_01900 2.7e-194 flhF N Flagellar biosynthesis regulator FlhF
HACLHNLC_01901 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HACLHNLC_01902 3.1e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HACLHNLC_01903 2e-130 fliR N Flagellar biosynthetic protein FliR
HACLHNLC_01904 2e-37 fliQ N Role in flagellar biosynthesis
HACLHNLC_01905 4.3e-110 fliP N Plays a role in the flagellum-specific transport system
HACLHNLC_01906 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
HACLHNLC_01907 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HACLHNLC_01908 5.4e-185 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HACLHNLC_01909 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HACLHNLC_01910 7.8e-57 fliL N Controls the rotational direction of flagella during chemotaxis
HACLHNLC_01911 4e-139 flgG N Flagellar basal body rod
HACLHNLC_01912 4.8e-73 flgD N Flagellar basal body rod modification protein
HACLHNLC_01913 2.7e-204 fliK N Flagellar hook-length control protein
HACLHNLC_01914 1.3e-47 ylxF S MgtE intracellular N domain
HACLHNLC_01915 1.7e-70 fliJ N Flagellar biosynthesis chaperone
HACLHNLC_01916 5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HACLHNLC_01917 3.7e-89 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HACLHNLC_01918 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HACLHNLC_01919 1.5e-257 fliF N The M ring may be actively involved in energy transduction
HACLHNLC_01920 2.5e-31 fliE N Flagellar hook-basal body
HACLHNLC_01921 1.2e-74 flgC N Belongs to the flagella basal body rod proteins family
HACLHNLC_01922 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HACLHNLC_01923 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HACLHNLC_01924 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HACLHNLC_01925 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HACLHNLC_01926 7.2e-172 xerC L tyrosine recombinase XerC
HACLHNLC_01927 3.7e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HACLHNLC_01928 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HACLHNLC_01929 6.8e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HACLHNLC_01930 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HACLHNLC_01931 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HACLHNLC_01932 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HACLHNLC_01933 2.3e-304 ylqG
HACLHNLC_01934 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HACLHNLC_01935 9.3e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HACLHNLC_01936 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HACLHNLC_01937 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HACLHNLC_01938 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HACLHNLC_01939 1.3e-61 ylqD S YlqD protein
HACLHNLC_01940 1.7e-35 ylqC S Belongs to the UPF0109 family
HACLHNLC_01941 4.2e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HACLHNLC_01942 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HACLHNLC_01943 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HACLHNLC_01944 8.5e-142 S Phosphotransferase enzyme family
HACLHNLC_01945 4.1e-173 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HACLHNLC_01946 0.0 smc D Required for chromosome condensation and partitioning
HACLHNLC_01947 1.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HACLHNLC_01948 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HACLHNLC_01949 4.6e-129 IQ reductase
HACLHNLC_01950 2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HACLHNLC_01951 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HACLHNLC_01952 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HACLHNLC_01953 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HACLHNLC_01954 7.1e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HACLHNLC_01955 4.8e-117 sdaAB 4.3.1.17 E L-serine dehydratase
HACLHNLC_01956 3.8e-304 yloV S kinase related to dihydroxyacetone kinase
HACLHNLC_01957 5.5e-59 asp S protein conserved in bacteria
HACLHNLC_01958 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HACLHNLC_01959 1.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
HACLHNLC_01960 9.4e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HACLHNLC_01961 8.2e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HACLHNLC_01962 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HACLHNLC_01963 1.7e-139 stp 3.1.3.16 T phosphatase
HACLHNLC_01964 3.4e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HACLHNLC_01965 6.6e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HACLHNLC_01966 6.6e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HACLHNLC_01967 3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HACLHNLC_01968 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HACLHNLC_01969 9.7e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HACLHNLC_01970 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HACLHNLC_01971 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HACLHNLC_01972 1.5e-40 ylzA S Belongs to the UPF0296 family
HACLHNLC_01973 6.5e-154 yloC S stress-induced protein
HACLHNLC_01974 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HACLHNLC_01975 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HACLHNLC_01976 4.5e-80 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HACLHNLC_01977 7.6e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HACLHNLC_01978 5.3e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HACLHNLC_01979 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HACLHNLC_01980 1.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HACLHNLC_01981 9.2e-179 cysP P phosphate transporter
HACLHNLC_01982 8.5e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HACLHNLC_01984 3.8e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HACLHNLC_01985 1.1e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HACLHNLC_01986 6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HACLHNLC_01987 5.9e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HACLHNLC_01988 0.0 carB 6.3.5.5 F Belongs to the CarB family
HACLHNLC_01989 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HACLHNLC_01990 2.3e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HACLHNLC_01991 5.3e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HACLHNLC_01992 8e-233 pyrP F Xanthine uracil
HACLHNLC_01993 1.8e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HACLHNLC_01994 1.8e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HACLHNLC_01995 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HACLHNLC_01996 3.8e-63 dksA T COG1734 DnaK suppressor protein
HACLHNLC_01997 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HACLHNLC_01998 8.9e-68 divIVA D Cell division initiation protein
HACLHNLC_01999 3.6e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HACLHNLC_02000 5.2e-41 yggT S membrane
HACLHNLC_02001 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HACLHNLC_02002 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HACLHNLC_02003 4.4e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HACLHNLC_02004 2.2e-38 ylmC S sporulation protein
HACLHNLC_02005 4.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
HACLHNLC_02006 2.9e-145 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HACLHNLC_02007 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACLHNLC_02008 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACLHNLC_02009 5.8e-161 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HACLHNLC_02010 0.0 bpr O COG1404 Subtilisin-like serine proteases
HACLHNLC_02011 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HACLHNLC_02012 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HACLHNLC_02013 8.7e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HACLHNLC_02014 3.7e-168 murB 1.3.1.98 M cell wall formation
HACLHNLC_02015 8.7e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HACLHNLC_02016 2.2e-185 spoVE D Belongs to the SEDS family
HACLHNLC_02017 1.7e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HACLHNLC_02018 2.2e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HACLHNLC_02019 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HACLHNLC_02020 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HACLHNLC_02021 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HACLHNLC_02022 2.9e-52 ftsL D Essential cell division protein
HACLHNLC_02023 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HACLHNLC_02024 8.9e-78 mraZ K Belongs to the MraZ family
HACLHNLC_02025 7e-311 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HACLHNLC_02026 1.1e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HACLHNLC_02027 8.1e-90 ylbP K n-acetyltransferase
HACLHNLC_02028 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HACLHNLC_02029 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HACLHNLC_02030 3.6e-88 yceD S metal-binding, possibly nucleic acid-binding protein
HACLHNLC_02031 1e-229 ylbM S Belongs to the UPF0348 family
HACLHNLC_02032 6.7e-187 ylbL T Belongs to the peptidase S16 family
HACLHNLC_02033 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HACLHNLC_02034 1.1e-215 ylbJ S Sporulation integral membrane protein YlbJ
HACLHNLC_02035 2.8e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HACLHNLC_02036 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
HACLHNLC_02038 7.2e-43 ylbG S UPF0298 protein
HACLHNLC_02039 1.2e-71 ylbF S Belongs to the UPF0342 family
HACLHNLC_02040 8.8e-37 ylbE S YlbE-like protein
HACLHNLC_02041 1.3e-56 ylbD S Putative coat protein
HACLHNLC_02042 1.5e-197 ylbC S protein with SCP PR1 domains
HACLHNLC_02043 3.1e-72 ylbB T COG0517 FOG CBS domain
HACLHNLC_02044 8.5e-60 ylbA S YugN-like family
HACLHNLC_02045 4.8e-165 ctaG S cytochrome c oxidase
HACLHNLC_02046 4.6e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HACLHNLC_02047 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HACLHNLC_02048 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HACLHNLC_02049 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HACLHNLC_02050 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HACLHNLC_02051 2e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HACLHNLC_02052 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HACLHNLC_02053 4.5e-214 ftsW D Belongs to the SEDS family
HACLHNLC_02054 8.7e-44 ylaN S Belongs to the UPF0358 family
HACLHNLC_02055 5.4e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
HACLHNLC_02056 2.2e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HACLHNLC_02057 1.2e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HACLHNLC_02058 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HACLHNLC_02059 1e-33 ylaI S protein conserved in bacteria
HACLHNLC_02060 1.7e-48 ylaH S YlaH-like protein
HACLHNLC_02061 0.0 typA T GTP-binding protein TypA
HACLHNLC_02062 6.7e-24 S Family of unknown function (DUF5325)
HACLHNLC_02063 6.3e-39 ylaE
HACLHNLC_02064 3.7e-13 sigC S Putative zinc-finger
HACLHNLC_02065 3.8e-93 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HACLHNLC_02066 1.7e-44 ylaB
HACLHNLC_02067 3.1e-193 ylaA
HACLHNLC_02068 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HACLHNLC_02069 5.8e-82 ykzC S Acetyltransferase (GNAT) family
HACLHNLC_02070 2.3e-150 suhB 3.1.3.25 G Inositol monophosphatase
HACLHNLC_02071 9.7e-25 ykzI
HACLHNLC_02072 4.9e-119 yktB S Belongs to the UPF0637 family
HACLHNLC_02073 1.6e-42 yktA S Belongs to the UPF0223 family
HACLHNLC_02074 3.1e-278 speA 4.1.1.19 E Arginine
HACLHNLC_02075 7.7e-138 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
HACLHNLC_02076 2.1e-45 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HACLHNLC_02077 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HACLHNLC_02078 1.3e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HACLHNLC_02079 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HACLHNLC_02080 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HACLHNLC_02081 4.3e-208 V Beta-lactamase
HACLHNLC_02082 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
HACLHNLC_02083 0.0 Q Polyketide synthase of type I
HACLHNLC_02084 0.0 Q Polyketide synthase of type I
HACLHNLC_02085 0.0 Q Polyketide synthase of type I
HACLHNLC_02086 0.0 Q Polyketide synthase of type I
HACLHNLC_02087 0.0 Q polyketide synthase
HACLHNLC_02088 0.0 Q Polyketide synthase of type I
HACLHNLC_02089 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HACLHNLC_02090 5e-103 recN L Putative cell-wall binding lipoprotein
HACLHNLC_02092 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HACLHNLC_02093 8e-148 ykrA S hydrolases of the HAD superfamily
HACLHNLC_02094 8.2e-31 ykzG S Belongs to the UPF0356 family
HACLHNLC_02095 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HACLHNLC_02096 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HACLHNLC_02097 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
HACLHNLC_02098 2.9e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HACLHNLC_02099 6.3e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HACLHNLC_02100 2.1e-45 abrB K of stationary sporulation gene expression
HACLHNLC_02101 1e-182 mreB D Rod-share determining protein MreBH
HACLHNLC_02102 5.5e-12 S Uncharacterized protein YkpC
HACLHNLC_02103 5e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HACLHNLC_02104 5.3e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HACLHNLC_02105 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HACLHNLC_02106 9.8e-37 ykoA
HACLHNLC_02107 1.9e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HACLHNLC_02108 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HACLHNLC_02109 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HACLHNLC_02110 1e-131 fruR K Transcriptional regulator
HACLHNLC_02111 3e-210 yknZ V ABC transporter (permease)
HACLHNLC_02112 3e-122 macB V ABC transporter, ATP-binding protein
HACLHNLC_02113 1.4e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HACLHNLC_02114 1.2e-105 yknW S Yip1 domain
HACLHNLC_02115 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HACLHNLC_02116 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HACLHNLC_02117 4.5e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HACLHNLC_02118 1.2e-244 moeA 2.10.1.1 H molybdopterin
HACLHNLC_02119 2.5e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HACLHNLC_02120 1.4e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HACLHNLC_02121 2.5e-162 yknT
HACLHNLC_02122 4.5e-98 rok K Repressor of ComK
HACLHNLC_02123 1.4e-69 ykuV CO thiol-disulfide
HACLHNLC_02124 7e-139 ykuT M Mechanosensitive ion channel
HACLHNLC_02125 4.8e-38 ykuS S Belongs to the UPF0180 family
HACLHNLC_02126 7.6e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HACLHNLC_02127 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HACLHNLC_02128 1.3e-78 fld C Flavodoxin
HACLHNLC_02129 1.1e-169 ykuO
HACLHNLC_02130 6.1e-90 fld C Flavodoxin
HACLHNLC_02131 4.6e-168 ccpC K Transcriptional regulator
HACLHNLC_02132 1e-75 ykuL S CBS domain
HACLHNLC_02133 2.1e-25 ykzF S Antirepressor AbbA
HACLHNLC_02134 4.9e-93 ykuK S Ribonuclease H-like
HACLHNLC_02135 3.9e-37 ykuJ S protein conserved in bacteria
HACLHNLC_02136 1.5e-233 ykuI T Diguanylate phosphodiesterase
HACLHNLC_02138 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACLHNLC_02139 8.9e-156 ykuE S Metallophosphoesterase
HACLHNLC_02140 9.2e-89 ykuD S protein conserved in bacteria
HACLHNLC_02141 3e-240 ykuC EGP Major facilitator Superfamily
HACLHNLC_02142 1.4e-83 ykyB S YkyB-like protein
HACLHNLC_02143 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
HACLHNLC_02144 2.3e-09
HACLHNLC_02145 3.9e-215 patA 2.6.1.1 E Aminotransferase
HACLHNLC_02146 4.4e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
HACLHNLC_02147 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HACLHNLC_02148 4.9e-113 ykwD J protein with SCP PR1 domains
HACLHNLC_02149 3.9e-50
HACLHNLC_02150 2.3e-156 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HACLHNLC_02151 1.2e-264 mcpC NT chemotaxis protein
HACLHNLC_02152 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
HACLHNLC_02153 1.4e-37 splA S Transcriptional regulator
HACLHNLC_02154 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HACLHNLC_02155 2.1e-39 ptsH G phosphocarrier protein HPr
HACLHNLC_02156 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACLHNLC_02157 4.3e-155 glcT K antiterminator
HACLHNLC_02158 1e-176 ykvZ 5.1.1.1 K Transcriptional regulator
HACLHNLC_02160 2.4e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HACLHNLC_02161 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HACLHNLC_02162 5.9e-88 stoA CO thiol-disulfide
HACLHNLC_02163 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HACLHNLC_02164 1.8e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
HACLHNLC_02165 7.9e-28
HACLHNLC_02166 7.8e-25 ykvS S protein conserved in bacteria
HACLHNLC_02167 1.6e-42 ykvR S Protein of unknown function (DUF3219)
HACLHNLC_02168 1e-131 IQ Enoyl-(Acyl carrier protein) reductase
HACLHNLC_02169 3.4e-58 ykvN K Transcriptional regulator
HACLHNLC_02171 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HACLHNLC_02172 6.4e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HACLHNLC_02173 1.8e-80 queD 4.1.2.50, 4.2.3.12 H synthase
HACLHNLC_02174 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HACLHNLC_02175 2.5e-187
HACLHNLC_02176 1.3e-182 ykvI S membrane
HACLHNLC_02177 0.0 clpE O Belongs to the ClpA ClpB family
HACLHNLC_02178 1.1e-136 motA N flagellar motor
HACLHNLC_02179 2.7e-127 motB N Flagellar motor protein
HACLHNLC_02180 5.5e-77 ykvE K transcriptional
HACLHNLC_02181 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HACLHNLC_02182 3.4e-10 S Spo0E like sporulation regulatory protein
HACLHNLC_02183 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HACLHNLC_02184 6.5e-116 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HACLHNLC_02185 1.1e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HACLHNLC_02186 1.3e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HACLHNLC_02187 1.2e-227 mtnE 2.6.1.83 E Aminotransferase
HACLHNLC_02188 8.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HACLHNLC_02189 2.2e-226 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HACLHNLC_02190 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HACLHNLC_02192 1.1e-84 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HACLHNLC_02193 0.0 kinE 2.7.13.3 T Histidine kinase
HACLHNLC_02194 2.5e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HACLHNLC_02195 7.9e-24 ykzE
HACLHNLC_02196 1.6e-112 ydfR S Protein of unknown function (DUF421)
HACLHNLC_02197 4.3e-242 ktrB P COG0168 Trk-type K transport systems, membrane components
HACLHNLC_02198 4.1e-156 htpX O Belongs to the peptidase M48B family
HACLHNLC_02199 2.3e-125 ykrK S Domain of unknown function (DUF1836)
HACLHNLC_02200 2.5e-26 sspD S small acid-soluble spore protein
HACLHNLC_02201 3.1e-119 rsgI S Anti-sigma factor N-terminus
HACLHNLC_02202 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACLHNLC_02203 3e-134 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HACLHNLC_02204 6.6e-99 ykoX S membrane-associated protein
HACLHNLC_02205 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HACLHNLC_02206 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HACLHNLC_02207 2.2e-99 ykoP G polysaccharide deacetylase
HACLHNLC_02208 5e-81 ykoM K transcriptional
HACLHNLC_02209 3.1e-26 ykoL
HACLHNLC_02210 1.9e-16
HACLHNLC_02211 5.4e-53 tnrA K transcriptional
HACLHNLC_02212 4.2e-237 mgtE P Acts as a magnesium transporter
HACLHNLC_02214 1e-245 ydhD M Glycosyl hydrolase
HACLHNLC_02215 2.2e-97 ykoE S ABC-type cobalt transport system, permease component
HACLHNLC_02216 1.2e-307 P ABC transporter, ATP-binding protein
HACLHNLC_02217 1.8e-131 ykoC P Cobalt transport protein
HACLHNLC_02218 1.2e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HACLHNLC_02219 2.5e-175 isp O Belongs to the peptidase S8 family
HACLHNLC_02220 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HACLHNLC_02221 3.3e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HACLHNLC_02222 2.7e-216 hcaT 1.5.1.2 EGP Major facilitator Superfamily
HACLHNLC_02223 7.5e-125 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
HACLHNLC_02224 2.2e-215 M Glycosyl transferase family 2
HACLHNLC_02226 1.3e-57 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HACLHNLC_02227 7.9e-70 ohrB O Organic hydroperoxide resistance protein
HACLHNLC_02228 2.2e-85 ohrR K COG1846 Transcriptional regulators
HACLHNLC_02229 9.6e-71 ohrA O Organic hydroperoxide resistance protein
HACLHNLC_02230 3.6e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HACLHNLC_02231 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HACLHNLC_02232 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HACLHNLC_02233 3.4e-49 ykkD P Multidrug resistance protein
HACLHNLC_02234 9.4e-53 ykkC P Multidrug resistance protein
HACLHNLC_02235 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HACLHNLC_02236 1.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HACLHNLC_02237 2.5e-158 ykgA E Amidinotransferase
HACLHNLC_02238 5.1e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
HACLHNLC_02239 2.1e-182 ykfD E Belongs to the ABC transporter superfamily
HACLHNLC_02240 1.6e-171 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HACLHNLC_02241 3e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HACLHNLC_02242 6.4e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HACLHNLC_02243 0.0 dppE E ABC transporter substrate-binding protein
HACLHNLC_02244 7.7e-191 dppD P Belongs to the ABC transporter superfamily
HACLHNLC_02245 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACLHNLC_02246 1.9e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HACLHNLC_02247 1.6e-154 dppA E D-aminopeptidase
HACLHNLC_02249 1.8e-284 yubD P Major Facilitator Superfamily
HACLHNLC_02250 3.3e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HACLHNLC_02252 2.9e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HACLHNLC_02253 3.8e-309 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HACLHNLC_02254 4.8e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HACLHNLC_02255 3.2e-242 steT E amino acid
HACLHNLC_02256 3.2e-107 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HACLHNLC_02257 5.8e-175 pit P phosphate transporter
HACLHNLC_02258 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HACLHNLC_02259 8.7e-23 spoIISB S Stage II sporulation protein SB
HACLHNLC_02260 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HACLHNLC_02261 1.3e-38 xhlB S SPP1 phage holin
HACLHNLC_02262 8.7e-38 xhlA S Haemolysin XhlA
HACLHNLC_02263 6.6e-139 xepA
HACLHNLC_02264 6.5e-30 xkdX
HACLHNLC_02266 3.8e-91
HACLHNLC_02267 1.2e-26
HACLHNLC_02268 5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HACLHNLC_02269 5.1e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HACLHNLC_02270 1.4e-56 xkdS S Protein of unknown function (DUF2634)
HACLHNLC_02271 7.2e-32 xkdR S Protein of unknown function (DUF2577)
HACLHNLC_02272 2.7e-161 xkdQ 3.2.1.96 G NLP P60 protein
HACLHNLC_02273 6.6e-111 xkdP S Lysin motif
HACLHNLC_02274 1.2e-183 xkdO L Transglycosylase SLT domain
HACLHNLC_02275 3.4e-19
HACLHNLC_02276 4.9e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
HACLHNLC_02277 2e-74 xkdM S Phage tail tube protein
HACLHNLC_02278 1e-225 xkdK S Phage tail sheath C-terminal domain
HACLHNLC_02279 3.1e-14
HACLHNLC_02280 8.3e-57 xkdJ
HACLHNLC_02281 9.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
HACLHNLC_02282 4.2e-43 yqbH S Domain of unknown function (DUF3599)
HACLHNLC_02283 3.3e-46 yqbG S Protein of unknown function (DUF3199)
HACLHNLC_02284 1e-157 xkdG S Phage capsid family
HACLHNLC_02285 7.5e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
HACLHNLC_02286 1.3e-241 yqbA S portal protein
HACLHNLC_02287 7.9e-209 xtmB S phage terminase, large subunit
HACLHNLC_02288 6.8e-110 xtmA L phage terminase small subunit
HACLHNLC_02289 6.3e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HACLHNLC_02290 2e-10 yqaO S Phage-like element PBSX protein XtrA
HACLHNLC_02293 8.5e-153 xkdC L Bacterial dnaA protein
HACLHNLC_02295 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
HACLHNLC_02296 2.3e-110 xkdA E IrrE N-terminal-like domain
HACLHNLC_02298 6.7e-110 yjqB S phage-related replication protein
HACLHNLC_02299 4.7e-61 yjqA S Bacterial PH domain
HACLHNLC_02300 8.5e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HACLHNLC_02302 4.9e-215 S response regulator aspartate phosphatase
HACLHNLC_02303 3.1e-78 yjoA S DinB family
HACLHNLC_02304 3.9e-131 MA20_18170 S membrane transporter protein
HACLHNLC_02305 1.1e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HACLHNLC_02306 1.5e-277 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HACLHNLC_02307 3.4e-183 exuR K transcriptional
HACLHNLC_02308 1.9e-253 yjmB G symporter YjmB
HACLHNLC_02309 1.5e-277 uxaC 5.3.1.12 G glucuronate isomerase
HACLHNLC_02310 1.3e-218 yjlD 1.6.99.3 C NADH dehydrogenase
HACLHNLC_02311 7e-66 yjlC S Protein of unknown function (DUF1641)
HACLHNLC_02312 7.5e-91 yjlB S Cupin domain
HACLHNLC_02313 1.6e-177 yjlA EG Putative multidrug resistance efflux transporter
HACLHNLC_02314 6.4e-131 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
HACLHNLC_02315 1.6e-122 ybbM S transport system, permease component
HACLHNLC_02316 3.3e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HACLHNLC_02317 4.4e-28
HACLHNLC_02318 2.3e-223 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HACLHNLC_02319 9.4e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HACLHNLC_02320 1.6e-91 yjgD S Protein of unknown function (DUF1641)
HACLHNLC_02321 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HACLHNLC_02322 1.7e-102 yjgB S Domain of unknown function (DUF4309)
HACLHNLC_02323 6.7e-66 T PhoQ Sensor
HACLHNLC_02324 7.5e-22 yjfB S Putative motility protein
HACLHNLC_02326 8.1e-106 yhiD S MgtC SapB transporter
HACLHNLC_02329 7.8e-123 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HACLHNLC_02330 2.2e-137 lacR K COG1349 Transcriptional regulators of sugar metabolism
HACLHNLC_02331 6.2e-284 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HACLHNLC_02332 2e-49 lacF 2.7.1.207 G phosphotransferase system
HACLHNLC_02333 1.2e-310 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HACLHNLC_02334 2.5e-214 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HACLHNLC_02335 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HACLHNLC_02336 4.8e-290 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HACLHNLC_02337 2.3e-220 ganA 3.2.1.89 G arabinogalactan
HACLHNLC_02338 1.4e-81 napB K helix_turn_helix multiple antibiotic resistance protein
HACLHNLC_02339 5.9e-250 yfjF EGP Belongs to the major facilitator superfamily
HACLHNLC_02340 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
HACLHNLC_02341 1.6e-163 bla 3.5.2.6 V beta-lactamase
HACLHNLC_02342 3.5e-59 E Glyoxalase-like domain
HACLHNLC_02345 2.1e-204 M nucleic acid phosphodiester bond hydrolysis
HACLHNLC_02346 6.4e-29
HACLHNLC_02347 2.7e-38
HACLHNLC_02348 3.4e-22
HACLHNLC_02350 1.6e-08
HACLHNLC_02353 1.2e-44 L COG2963 Transposase and inactivated derivatives
HACLHNLC_02358 2e-08
HACLHNLC_02361 1.6e-08
HACLHNLC_02367 2.7e-109 hlyIII S protein, Hemolysin III
HACLHNLC_02368 2.6e-175 pspF K Transcriptional regulator
HACLHNLC_02369 3.1e-242 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HACLHNLC_02370 2.6e-39 ypmP S Protein of unknown function (DUF2535)
HACLHNLC_02371 7.4e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HACLHNLC_02372 1.2e-135 ypmR E GDSL-like Lipase/Acylhydrolase
HACLHNLC_02373 1.6e-97 ypmS S protein conserved in bacteria
HACLHNLC_02374 1.4e-66 ypoP K transcriptional
HACLHNLC_02375 7.8e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HACLHNLC_02376 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HACLHNLC_02377 2.6e-103 4.2.1.115 GM Polysaccharide biosynthesis protein
HACLHNLC_02378 4.5e-305 yokA L Recombinase
HACLHNLC_02379 2.7e-76 yokF 3.1.31.1 L RNA catabolic process
HACLHNLC_02380 2.1e-77 yokH G SMI1 / KNR4 family
HACLHNLC_02381 1.8e-288 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HACLHNLC_02382 4.8e-52 S SMI1-KNR4 cell-wall
HACLHNLC_02385 1.4e-62 3.4.24.40 S amine dehydrogenase activity
HACLHNLC_02386 6.8e-36 3.4.24.40 S amine dehydrogenase activity
HACLHNLC_02388 4.8e-194 S aspartate phosphatase
HACLHNLC_02390 2.2e-08
HACLHNLC_02392 1.4e-69 yoaW
HACLHNLC_02397 8.9e-14 S Protein of unknown function (DUF4236)
HACLHNLC_02398 1.7e-39 K Putative DNA-binding domain
HACLHNLC_02400 1.4e-09 L Belongs to the 'phage' integrase family
HACLHNLC_02401 5e-12 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HACLHNLC_02402 6.3e-207 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HACLHNLC_02403 1.4e-62 S SMI1-KNR4 cell-wall
HACLHNLC_02404 4.3e-63
HACLHNLC_02405 1.1e-20 1.2.1.9 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HACLHNLC_02407 9.3e-147 S aspartate phosphatase
HACLHNLC_02408 7.4e-48 S aspartate phosphatase
HACLHNLC_02409 2.9e-73 yoqH M LysM domain
HACLHNLC_02410 3.4e-65 S Acetyltransferase (GNAT) domain
HACLHNLC_02411 9.6e-81
HACLHNLC_02415 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
HACLHNLC_02416 6.1e-221 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HACLHNLC_02417 3.3e-180 cgeB S Spore maturation protein
HACLHNLC_02418 1.6e-52 cgeA
HACLHNLC_02419 4.5e-249 cgeD M maturation of the outermost layer of the spore
HACLHNLC_02420 3.2e-144 yiiD K acetyltransferase
HACLHNLC_02422 2e-63 yosT L Bacterial transcription activator, effector binding domain
HACLHNLC_02423 5.4e-245 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HACLHNLC_02424 5.8e-126 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HACLHNLC_02425 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HACLHNLC_02426 4.8e-254 yodQ 3.5.1.16 E Acetylornithine deacetylase
HACLHNLC_02427 1e-159 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HACLHNLC_02428 6.1e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
HACLHNLC_02429 1.3e-44 yokU S YokU-like protein, putative antitoxin
HACLHNLC_02430 4.1e-36 yozE S Belongs to the UPF0346 family
HACLHNLC_02431 1.7e-125 yodN
HACLHNLC_02433 6.2e-24 yozD S YozD-like protein
HACLHNLC_02434 5.2e-102 yodM 3.6.1.27 I Acid phosphatase homologues
HACLHNLC_02435 3.3e-55 yodL S YodL-like
HACLHNLC_02437 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HACLHNLC_02438 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HACLHNLC_02439 4.3e-34 yodI
HACLHNLC_02440 2.4e-127 yodH Q Methyltransferase
HACLHNLC_02441 2.1e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HACLHNLC_02442 6.3e-131 yydK K Transcriptional regulator
HACLHNLC_02443 6e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HACLHNLC_02444 1.8e-281 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
HACLHNLC_02445 4.6e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HACLHNLC_02446 1.4e-19 S Protein of unknown function (DUF3311)
HACLHNLC_02447 2.2e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
HACLHNLC_02448 3.6e-95 mhqD S Carboxylesterase
HACLHNLC_02449 4.5e-106 yodC C nitroreductase
HACLHNLC_02450 1.4e-56 yodB K transcriptional
HACLHNLC_02451 4.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
HACLHNLC_02452 5.9e-67 yodA S tautomerase
HACLHNLC_02454 8.6e-81 yozR S COG0071 Molecular chaperone (small heat shock protein)
HACLHNLC_02455 2e-163 rarD S -transporter
HACLHNLC_02456 4.9e-23
HACLHNLC_02457 9.7e-61 yojF S Protein of unknown function (DUF1806)
HACLHNLC_02458 2.5e-126 yojG S deacetylase
HACLHNLC_02459 1.9e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HACLHNLC_02460 9.8e-242 norM V Multidrug efflux pump
HACLHNLC_02462 1.8e-110 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HACLHNLC_02463 1.9e-225 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HACLHNLC_02464 3.3e-220 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HACLHNLC_02465 5.9e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HACLHNLC_02466 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
HACLHNLC_02467 0.0 yojO P Von Willebrand factor
HACLHNLC_02468 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HACLHNLC_02469 7.2e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HACLHNLC_02470 3.4e-143 S Metallo-beta-lactamase superfamily
HACLHNLC_02471 2.5e-159 yocS S -transporter
HACLHNLC_02472 3.9e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HACLHNLC_02473 3.2e-166 sodA 1.15.1.1 P Superoxide dismutase
HACLHNLC_02474 4e-33 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HACLHNLC_02475 4.1e-303 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HACLHNLC_02476 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HACLHNLC_02477 3.6e-31 yozC
HACLHNLC_02479 2.4e-56 yozO S Bacterial PH domain
HACLHNLC_02480 8.5e-37 yocN
HACLHNLC_02481 1.4e-43 yozN
HACLHNLC_02482 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
HACLHNLC_02483 1.7e-08
HACLHNLC_02484 5.9e-10 yocL
HACLHNLC_02485 4.7e-53 dksA T general stress protein
HACLHNLC_02487 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HACLHNLC_02488 0.0 recQ 3.6.4.12 L DNA helicase
HACLHNLC_02489 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
HACLHNLC_02491 9.9e-188 yocD 3.4.17.13 V peptidase S66
HACLHNLC_02492 2.5e-94 yocC
HACLHNLC_02493 6.8e-139 yocB J Protein required for attachment to host cells
HACLHNLC_02494 1.8e-90 yozB S membrane
HACLHNLC_02495 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HACLHNLC_02496 3.4e-55 czrA K transcriptional
HACLHNLC_02497 1.9e-92 yobW
HACLHNLC_02498 6.1e-134 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HACLHNLC_02499 2.2e-94 yobS K Transcriptional regulator
HACLHNLC_02500 7.8e-134 yobQ K helix_turn_helix, arabinose operon control protein
HACLHNLC_02501 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HACLHNLC_02502 2.4e-296 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HACLHNLC_02503 2.4e-54 S SMI1-KNR4 cell-wall
HACLHNLC_02504 7.1e-44
HACLHNLC_02505 1e-99 hpr K helix_turn_helix multiple antibiotic resistance protein
HACLHNLC_02507 1.4e-25 yoaF
HACLHNLC_02508 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HACLHNLC_02509 3.8e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HACLHNLC_02510 3.6e-274 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
HACLHNLC_02511 1.4e-202 yoaB EGP Major facilitator Superfamily
HACLHNLC_02512 2.3e-139 yoxB
HACLHNLC_02513 3.1e-39 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HACLHNLC_02514 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HACLHNLC_02515 1.5e-222 K helix_turn_helix, arabinose operon control protein
HACLHNLC_02516 3.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
HACLHNLC_02517 5e-75 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
HACLHNLC_02518 1e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HACLHNLC_02519 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HACLHNLC_02520 8.7e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HACLHNLC_02521 3.3e-153 gltC K Transcriptional regulator
HACLHNLC_02522 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HACLHNLC_02523 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HACLHNLC_02524 1e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HACLHNLC_02525 1.8e-156 gltR1 K Transcriptional regulator
HACLHNLC_02527 1.8e-50 ybzH K Helix-turn-helix domain
HACLHNLC_02528 3e-199 ybcL EGP Major facilitator Superfamily
HACLHNLC_02529 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HACLHNLC_02530 4.3e-33 yoeD G Helix-turn-helix domain
HACLHNLC_02531 3.5e-97 L Integrase
HACLHNLC_02533 1.9e-95 yoeB S IseA DL-endopeptidase inhibitor
HACLHNLC_02534 1.3e-246 yoeA V MATE efflux family protein
HACLHNLC_02535 9.3e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
HACLHNLC_02536 2.4e-270 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HACLHNLC_02537 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_02538 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_02539 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_02540 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_02541 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
HACLHNLC_02542 1.2e-64 yngL S Protein of unknown function (DUF1360)
HACLHNLC_02543 9.2e-305 yngK T Glycosyl hydrolase-like 10
HACLHNLC_02544 8.3e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HACLHNLC_02545 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HACLHNLC_02546 5.5e-253 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HACLHNLC_02547 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HACLHNLC_02548 1.4e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HACLHNLC_02549 7.5e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HACLHNLC_02550 1.8e-289 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HACLHNLC_02551 3.2e-104 yngC S SNARE associated Golgi protein
HACLHNLC_02552 5.5e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HACLHNLC_02553 3.7e-72 yngA S membrane
HACLHNLC_02554 7.6e-143 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HACLHNLC_02555 2.4e-256 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HACLHNLC_02556 1.3e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HACLHNLC_02557 1.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HACLHNLC_02558 8.2e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HACLHNLC_02559 2e-222 bioI 1.14.14.46 C Cytochrome P450
HACLHNLC_02560 6.5e-252 yxjC EG COG2610 H gluconate symporter and related permeases
HACLHNLC_02561 2.4e-124 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HACLHNLC_02562 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HACLHNLC_02563 1.2e-138 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HACLHNLC_02564 1.1e-223 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HACLHNLC_02565 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_02566 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_02567 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_02568 8e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HACLHNLC_02569 5.7e-252 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
HACLHNLC_02570 3.4e-129 T Transcriptional regulatory protein, C terminal
HACLHNLC_02571 1e-233 T PhoQ Sensor
HACLHNLC_02572 1.3e-51 S Domain of unknown function (DUF4870)
HACLHNLC_02573 3.1e-289 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HACLHNLC_02575 5.9e-216 S Platelet-activating factor acetylhydrolase, isoform II
HACLHNLC_02576 3.7e-26 yxlH EGP Major facilitator Superfamily
HACLHNLC_02577 3.2e-300 yndJ S YndJ-like protein
HACLHNLC_02578 3.1e-78 yndH S Domain of unknown function (DUF4166)
HACLHNLC_02579 2.3e-153 yndG S DoxX-like family
HACLHNLC_02580 6.6e-224 exuT G Sugar (and other) transporter
HACLHNLC_02581 1.1e-181 kdgR_1 K transcriptional
HACLHNLC_02582 7e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HACLHNLC_02583 1.1e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HACLHNLC_02584 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HACLHNLC_02585 6.5e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HACLHNLC_02586 2.1e-182 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HACLHNLC_02587 2.7e-250 agcS E Sodium alanine symporter
HACLHNLC_02588 5.1e-41 ynfC
HACLHNLC_02589 4.6e-13
HACLHNLC_02590 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HACLHNLC_02591 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HACLHNLC_02592 1.5e-68 yccU S CoA-binding protein
HACLHNLC_02593 1.9e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HACLHNLC_02594 6.3e-50 yneR S Belongs to the HesB IscA family
HACLHNLC_02595 3.7e-53 yneQ
HACLHNLC_02596 3.1e-74 yneP S Thioesterase-like superfamily
HACLHNLC_02597 2.7e-33 tlp S Belongs to the Tlp family
HACLHNLC_02599 6.3e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HACLHNLC_02600 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HACLHNLC_02601 2.2e-14 sspO S Belongs to the SspO family
HACLHNLC_02602 2.3e-19 sspP S Belongs to the SspP family
HACLHNLC_02603 3.2e-62 hspX O Spore coat protein
HACLHNLC_02604 2.5e-74 yneK S Protein of unknown function (DUF2621)
HACLHNLC_02605 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HACLHNLC_02606 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HACLHNLC_02607 1.7e-125 ccdA O cytochrome c biogenesis protein
HACLHNLC_02608 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
HACLHNLC_02609 2.3e-28 yneF S UPF0154 protein
HACLHNLC_02610 8.3e-81 yneE S Sporulation inhibitor of replication protein sirA
HACLHNLC_02611 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HACLHNLC_02612 9.8e-33 ynzC S UPF0291 protein
HACLHNLC_02613 7.7e-112 yneB L resolvase
HACLHNLC_02614 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HACLHNLC_02615 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HACLHNLC_02616 2.1e-12 yoaW
HACLHNLC_02617 4.6e-71 yndM S Protein of unknown function (DUF2512)
HACLHNLC_02618 3.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
HACLHNLC_02619 1.6e-07
HACLHNLC_02620 2.2e-143 yndL S Replication protein
HACLHNLC_02621 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HACLHNLC_02622 0.0 yobO M Pectate lyase superfamily protein
HACLHNLC_02624 6.1e-82 yvgO
HACLHNLC_02626 2.6e-117 AA10,CBM73 S Pfam:Chitin_bind_3
HACLHNLC_02627 6e-202 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACLHNLC_02628 4.2e-112 ynaE S Domain of unknown function (DUF3885)
HACLHNLC_02630 1.1e-56
HACLHNLC_02631 2e-97 J Acetyltransferase (GNAT) domain
HACLHNLC_02632 3.2e-135 yoaP 3.1.3.18 K YoaP-like
HACLHNLC_02634 1.5e-19 yoaW
HACLHNLC_02635 3.8e-69 ccmM S Bacterial transferase hexapeptide (six repeats)
HACLHNLC_02636 9.7e-186 adhP 1.1.1.1 C alcohol dehydrogenase
HACLHNLC_02637 8.6e-54 dinB S DinB family
HACLHNLC_02638 1.6e-16
HACLHNLC_02642 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HACLHNLC_02643 3.2e-286 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
HACLHNLC_02644 9.2e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HACLHNLC_02645 1.2e-216 xylR GK ROK family
HACLHNLC_02646 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HACLHNLC_02647 8.1e-252 xynT G MFS/sugar transport protein
HACLHNLC_02650 6.5e-13
HACLHNLC_02652 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
HACLHNLC_02653 1.6e-67 glnR K transcriptional
HACLHNLC_02654 6.3e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HACLHNLC_02655 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HACLHNLC_02656 1.3e-176 spoVK O stage V sporulation protein K
HACLHNLC_02657 1.9e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HACLHNLC_02670 2.7e-140 mta K transcriptional
HACLHNLC_02671 2.1e-160 yjfC O Predicted Zn-dependent protease (DUF2268)
HACLHNLC_02672 4.7e-224 ywbD 2.1.1.191 J Methyltransferase
HACLHNLC_02673 7.6e-67 ywbC 4.4.1.5 E glyoxalase
HACLHNLC_02674 3.5e-244 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HACLHNLC_02675 1.2e-265 epr 3.4.21.62 O Belongs to the peptidase S8 family
HACLHNLC_02676 2.8e-162 gspA M General stress
HACLHNLC_02677 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
HACLHNLC_02678 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HACLHNLC_02679 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
HACLHNLC_02680 2.3e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_02681 3.7e-229 dltB M membrane protein involved in D-alanine export
HACLHNLC_02682 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_02683 1.5e-227 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HACLHNLC_02684 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HACLHNLC_02685 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HACLHNLC_02686 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HACLHNLC_02687 2.8e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HACLHNLC_02688 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HACLHNLC_02689 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HACLHNLC_02690 3.8e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HACLHNLC_02691 4.3e-173 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACLHNLC_02692 3.9e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACLHNLC_02693 3e-167 cbrA3 P Periplasmic binding protein
HACLHNLC_02694 2.2e-57 arsR K transcriptional
HACLHNLC_02695 3.8e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HACLHNLC_02696 1.2e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HACLHNLC_02697 3.5e-49 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HACLHNLC_02698 1.2e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HACLHNLC_02699 2.1e-287 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HACLHNLC_02700 2.5e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HACLHNLC_02701 1.6e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
HACLHNLC_02702 9.2e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HACLHNLC_02703 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HACLHNLC_02704 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HACLHNLC_02705 1.2e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HACLHNLC_02706 5e-156 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HACLHNLC_02707 5.3e-293 cydD V ATP-binding protein
HACLHNLC_02708 1.7e-310 cydD V ATP-binding
HACLHNLC_02709 1.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HACLHNLC_02710 2.6e-266 cydA 1.10.3.14 C oxidase, subunit
HACLHNLC_02711 3.8e-214 cimH C COG3493 Na citrate symporter
HACLHNLC_02712 6e-157 yxkH G Polysaccharide deacetylase
HACLHNLC_02713 1.6e-205 msmK P Belongs to the ABC transporter superfamily
HACLHNLC_02714 9.1e-164 lrp QT PucR C-terminal helix-turn-helix domain
HACLHNLC_02715 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HACLHNLC_02716 4.9e-87 yxkC S Domain of unknown function (DUF4352)
HACLHNLC_02717 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HACLHNLC_02718 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HACLHNLC_02721 2.4e-86 yxjI S LURP-one-related
HACLHNLC_02722 5.9e-216 yxjG 2.1.1.14 E Methionine synthase
HACLHNLC_02723 4.8e-157 rlmA 2.1.1.187 Q Methyltransferase domain
HACLHNLC_02724 2.5e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HACLHNLC_02725 2.7e-75 T Domain of unknown function (DUF4163)
HACLHNLC_02726 1.4e-50 yxiS
HACLHNLC_02727 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HACLHNLC_02728 1.1e-221 citH C Citrate transporter
HACLHNLC_02729 1.5e-143 exoK GH16 M licheninase activity
HACLHNLC_02730 7e-150 licT K transcriptional antiterminator
HACLHNLC_02731 6e-222 yxiO S COG2270 Permeases of the major facilitator superfamily
HACLHNLC_02732 4.5e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HACLHNLC_02735 1.2e-08 S SMI1-KNR4 cell-wall
HACLHNLC_02736 2.5e-30 S SMI1-KNR4 cell-wall
HACLHNLC_02737 5e-84 yxiI S Protein of unknown function (DUF2716)
HACLHNLC_02739 1.7e-20
HACLHNLC_02740 1.2e-13 S YxiJ-like protein
HACLHNLC_02743 0.0 wapA M COG3209 Rhs family protein
HACLHNLC_02744 2.2e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
HACLHNLC_02745 1.2e-147 yxxF EG EamA-like transporter family
HACLHNLC_02746 1.3e-73 yxiE T Belongs to the universal stress protein A family
HACLHNLC_02747 6e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HACLHNLC_02748 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACLHNLC_02749 0.0 L HKD family nuclease
HACLHNLC_02751 7.2e-55 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HACLHNLC_02752 1.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HACLHNLC_02753 3.8e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HACLHNLC_02754 2.3e-287 hutH 4.3.1.3 E Histidine ammonia-lyase
HACLHNLC_02755 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HACLHNLC_02756 2.3e-237 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HACLHNLC_02757 5e-176 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HACLHNLC_02758 1.7e-252 lysP E amino acid
HACLHNLC_02759 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HACLHNLC_02760 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HACLHNLC_02761 2.1e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HACLHNLC_02762 3.3e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HACLHNLC_02763 4e-150 yidA S hydrolases of the HAD superfamily
HACLHNLC_02766 6e-11 yxeE
HACLHNLC_02767 8.4e-23 yxeD
HACLHNLC_02768 3e-34
HACLHNLC_02769 1.1e-175 fhuD P Periplasmic binding protein
HACLHNLC_02770 1.3e-57 yxeA S Protein of unknown function (DUF1093)
HACLHNLC_02771 0.0 yxdM V ABC transporter (permease)
HACLHNLC_02772 5.5e-141 yxdL V ABC transporter, ATP-binding protein
HACLHNLC_02773 5.7e-175 T PhoQ Sensor
HACLHNLC_02774 1e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACLHNLC_02775 7.8e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HACLHNLC_02776 1.7e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HACLHNLC_02777 9.5e-166 iolH G Xylose isomerase-like TIM barrel
HACLHNLC_02778 3.6e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HACLHNLC_02779 5.1e-232 iolF EGP Major facilitator Superfamily
HACLHNLC_02780 1.4e-175 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HACLHNLC_02781 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HACLHNLC_02782 8.3e-182 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HACLHNLC_02783 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HACLHNLC_02784 7.9e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HACLHNLC_02785 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
HACLHNLC_02786 4.9e-176 iolS C Aldo keto reductase
HACLHNLC_02787 1.9e-245 csbC EGP Major facilitator Superfamily
HACLHNLC_02788 0.0 htpG O Molecular chaperone. Has ATPase activity
HACLHNLC_02790 4.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
HACLHNLC_02791 6e-103 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HACLHNLC_02792 8.2e-202 desK 2.7.13.3 T Histidine kinase
HACLHNLC_02793 4.5e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HACLHNLC_02794 4.6e-216 yxbF K Bacterial regulatory proteins, tetR family
HACLHNLC_02795 3.9e-251 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HACLHNLC_02796 5.2e-141 S PQQ-like domain
HACLHNLC_02797 9.9e-60 S Family of unknown function (DUF5391)
HACLHNLC_02798 1.5e-49 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
HACLHNLC_02799 2.9e-202 EGP Major facilitator Superfamily
HACLHNLC_02800 8.4e-73 yxaI S membrane protein domain
HACLHNLC_02801 5.4e-124 E Ring-cleavage extradiol dioxygenase
HACLHNLC_02802 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HACLHNLC_02803 2.5e-286 ahpF O Alkyl hydroperoxide reductase
HACLHNLC_02804 1.9e-228 XK27_00240 S Fic/DOC family
HACLHNLC_02805 4.2e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
HACLHNLC_02806 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HACLHNLC_02807 6.4e-84 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HACLHNLC_02808 2.1e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HACLHNLC_02809 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HACLHNLC_02810 1.3e-92 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HACLHNLC_02811 7.2e-189 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HACLHNLC_02812 3.9e-177 S Fusaric acid resistance protein-like
HACLHNLC_02813 1.1e-18
HACLHNLC_02814 0.0 L AAA domain
HACLHNLC_02815 1.1e-80 F 5-carbamoylmethyl uridine residue modification
HACLHNLC_02816 1e-94 K NAD+ binding
HACLHNLC_02817 2.2e-79 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HACLHNLC_02818 7.9e-08 S YyzF-like protein
HACLHNLC_02820 1.4e-217 yycP
HACLHNLC_02821 9.2e-133 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HACLHNLC_02822 4.8e-182 C oxidoreductases (related to aryl-alcohol dehydrogenases)
HACLHNLC_02823 1.9e-83 yycN 2.3.1.128 K Acetyltransferase
HACLHNLC_02825 1.8e-201 S Histidine kinase
HACLHNLC_02826 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HACLHNLC_02827 1.5e-258 rocE E amino acid
HACLHNLC_02828 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HACLHNLC_02829 2.7e-61 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HACLHNLC_02830 2.2e-42 sdpR K transcriptional
HACLHNLC_02831 1.1e-259 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HACLHNLC_02832 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
HACLHNLC_02833 4.8e-304 S ABC transporter
HACLHNLC_02834 4.5e-195 S Major Facilitator Superfamily
HACLHNLC_02835 1.6e-260
HACLHNLC_02836 6.9e-192 2.7.7.73, 2.7.7.80 H ThiF family
HACLHNLC_02837 3.6e-255 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HACLHNLC_02838 4.7e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACLHNLC_02839 1.2e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HACLHNLC_02840 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HACLHNLC_02841 3.2e-150 yycI S protein conserved in bacteria
HACLHNLC_02842 4.2e-261 yycH S protein conserved in bacteria
HACLHNLC_02843 0.0 vicK 2.7.13.3 T Histidine kinase
HACLHNLC_02844 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACLHNLC_02849 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HACLHNLC_02850 2.5e-71 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HACLHNLC_02851 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HACLHNLC_02852 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HACLHNLC_02854 3.5e-17 yycC K YycC-like protein
HACLHNLC_02855 1.1e-237 M Glycosyltransferase Family 4
HACLHNLC_02856 4.3e-205 S Ecdysteroid kinase
HACLHNLC_02857 2.4e-236 S Carbamoyl-phosphate synthase L chain, ATP binding domain
HACLHNLC_02858 7.3e-242 M Glycosyltransferase Family 4
HACLHNLC_02859 4.9e-122 S GlcNAc-PI de-N-acetylase
HACLHNLC_02860 3.4e-123 KLT COG0515 Serine threonine protein kinase
HACLHNLC_02861 1.4e-72 rplI J binds to the 23S rRNA
HACLHNLC_02862 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HACLHNLC_02863 1e-157 yybS S membrane
HACLHNLC_02865 1.1e-83 cotF M Spore coat protein
HACLHNLC_02866 4e-65 ydeP3 K Transcriptional regulator
HACLHNLC_02867 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HACLHNLC_02868 1.5e-155 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HACLHNLC_02869 7.7e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HACLHNLC_02870 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HACLHNLC_02871 4.5e-115 K FCD domain
HACLHNLC_02872 2.4e-76 dinB S PFAM DinB family protein
HACLHNLC_02873 1.7e-160 G Major Facilitator Superfamily
HACLHNLC_02874 2.4e-54 ypaA S Protein of unknown function (DUF1304)
HACLHNLC_02875 5.6e-115 drgA C nitroreductase
HACLHNLC_02876 5.4e-69 ydgJ K Winged helix DNA-binding domain
HACLHNLC_02877 2.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HACLHNLC_02878 5.6e-77 yybA 2.3.1.57 K transcriptional
HACLHNLC_02879 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
HACLHNLC_02880 2.3e-164 eaeH M Domain of Unknown Function (DUF1259)
HACLHNLC_02881 2.3e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
HACLHNLC_02882 1.2e-163 K Transcriptional regulator
HACLHNLC_02883 8.6e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HACLHNLC_02884 9.4e-251 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HACLHNLC_02885 5.5e-132 ydfC EG EamA-like transporter family
HACLHNLC_02886 1.9e-30 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HACLHNLC_02887 4e-81
HACLHNLC_02888 3.9e-69 ynaF
HACLHNLC_02890 4.2e-250 KLT Protein tyrosine kinase
HACLHNLC_02891 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HACLHNLC_02892 1.2e-160 yyaK S CAAX protease self-immunity
HACLHNLC_02893 2.6e-247 ydjK G Sugar (and other) transporter
HACLHNLC_02894 1.3e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HACLHNLC_02895 4.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HACLHNLC_02896 7.6e-143 xth 3.1.11.2 L exodeoxyribonuclease III
HACLHNLC_02897 2.4e-101 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HACLHNLC_02898 3.7e-105 adaA 3.2.2.21 K Transcriptional regulator
HACLHNLC_02899 1.1e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HACLHNLC_02900 4.2e-68 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HACLHNLC_02901 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HACLHNLC_02902 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HACLHNLC_02903 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HACLHNLC_02904 2.3e-33 yyzM S protein conserved in bacteria
HACLHNLC_02905 3.1e-176 yyaD S Membrane
HACLHNLC_02906 8.4e-82 4.2.1.103 K FR47-like protein
HACLHNLC_02907 6.2e-111 yyaC S Sporulation protein YyaC
HACLHNLC_02908 1.8e-148 spo0J K Belongs to the ParB family
HACLHNLC_02909 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
HACLHNLC_02910 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HACLHNLC_02911 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HACLHNLC_02912 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HACLHNLC_02913 1.2e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HACLHNLC_02914 1e-108 jag S single-stranded nucleic acid binding R3H
HACLHNLC_02915 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HACLHNLC_02916 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HACLHNLC_02917 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HACLHNLC_02918 7.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HACLHNLC_02919 2.4e-33 yaaA S S4 domain
HACLHNLC_02920 4.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HACLHNLC_02921 1.1e-37 yaaB S Domain of unknown function (DUF370)
HACLHNLC_02922 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HACLHNLC_02923 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HACLHNLC_02924 1.6e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HACLHNLC_02925 4.8e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HACLHNLC_02926 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HACLHNLC_02927 2.7e-114 ypjP S YpjP-like protein
HACLHNLC_02928 2.6e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HACLHNLC_02929 1e-75 yphP S Belongs to the UPF0403 family
HACLHNLC_02930 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HACLHNLC_02931 1.5e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
HACLHNLC_02932 7e-99 ypgQ S phosphohydrolase
HACLHNLC_02933 1.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HACLHNLC_02934 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HACLHNLC_02935 5.5e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HACLHNLC_02936 7.9e-31 cspD K Cold-shock protein
HACLHNLC_02937 1.3e-11 degR
HACLHNLC_02938 1.2e-36 S Protein of unknown function (DUF2564)
HACLHNLC_02939 1.5e-28 ypeQ S Zinc-finger
HACLHNLC_02940 5.3e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HACLHNLC_02941 1.2e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HACLHNLC_02942 4.2e-68 rnhA 3.1.26.4 L Ribonuclease
HACLHNLC_02944 3.5e-163 polA 2.7.7.7 L 5'3' exonuclease
HACLHNLC_02946 1e-38 ypbS S Protein of unknown function (DUF2533)
HACLHNLC_02947 0.0 ypbR S Dynamin family
HACLHNLC_02948 1.4e-89 ypbQ S protein conserved in bacteria
HACLHNLC_02949 2e-205 bcsA Q Naringenin-chalcone synthase
HACLHNLC_02950 1.5e-104 J Acetyltransferase (GNAT) domain
HACLHNLC_02951 6.2e-51 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HACLHNLC_02953 2.2e-97 ydfR S Protein of unknown function (DUF421)
HACLHNLC_02954 1.3e-99 yrdC 3.5.1.19 Q Isochorismatase family
HACLHNLC_02956 4.2e-234 pbuX F xanthine
HACLHNLC_02957 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HACLHNLC_02958 4.3e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HACLHNLC_02959 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HACLHNLC_02961 6.6e-22 S YpzG-like protein
HACLHNLC_02962 5.1e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HACLHNLC_02963 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HACLHNLC_02964 4.8e-99 ypsA S Belongs to the UPF0398 family
HACLHNLC_02965 9.9e-33 cotD S Inner spore coat protein D
HACLHNLC_02967 1.5e-236 yprB L RNase_H superfamily
HACLHNLC_02968 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HACLHNLC_02969 1.1e-86 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HACLHNLC_02970 3.8e-72 hspX O Belongs to the small heat shock protein (HSP20) family
HACLHNLC_02971 4.5e-45 yppG S YppG-like protein
HACLHNLC_02973 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
HACLHNLC_02976 1.1e-186 yppC S Protein of unknown function (DUF2515)
HACLHNLC_02977 8e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HACLHNLC_02978 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HACLHNLC_02979 4.3e-91 ypoC
HACLHNLC_02980 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HACLHNLC_02981 6.8e-130 dnaD L DNA replication protein DnaD
HACLHNLC_02982 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HACLHNLC_02983 9.7e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HACLHNLC_02984 1.2e-80 ypmB S protein conserved in bacteria
HACLHNLC_02985 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HACLHNLC_02986 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HACLHNLC_02987 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HACLHNLC_02988 6.5e-159 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HACLHNLC_02989 7e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HACLHNLC_02990 9.6e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HACLHNLC_02991 2.8e-216 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HACLHNLC_02992 1.1e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HACLHNLC_02993 1.9e-132 bshB1 S proteins, LmbE homologs
HACLHNLC_02994 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HACLHNLC_02995 5.9e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HACLHNLC_02996 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HACLHNLC_02997 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HACLHNLC_02998 1.9e-225 oxdC 4.1.1.2 G Oxalate decarboxylase
HACLHNLC_02999 5.1e-142 ypjB S sporulation protein
HACLHNLC_03000 4.1e-104 ypjA S membrane
HACLHNLC_03001 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HACLHNLC_03002 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HACLHNLC_03003 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HACLHNLC_03004 3.2e-77 ypiF S Protein of unknown function (DUF2487)
HACLHNLC_03005 2.1e-99 ypiB S Belongs to the UPF0302 family
HACLHNLC_03006 7.7e-233 S COG0457 FOG TPR repeat
HACLHNLC_03007 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HACLHNLC_03008 2e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HACLHNLC_03009 1.5e-200 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HACLHNLC_03010 2.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HACLHNLC_03011 6.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HACLHNLC_03012 4e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HACLHNLC_03013 2.5e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HACLHNLC_03014 3.1e-160 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HACLHNLC_03015 1.2e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HACLHNLC_03016 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HACLHNLC_03017 1.6e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HACLHNLC_03018 1.4e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HACLHNLC_03019 1.4e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HACLHNLC_03020 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HACLHNLC_03021 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HACLHNLC_03022 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HACLHNLC_03023 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HACLHNLC_03024 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HACLHNLC_03025 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
HACLHNLC_03026 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HACLHNLC_03027 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HACLHNLC_03028 1.6e-134 yphF
HACLHNLC_03029 3.3e-16 yphE S Protein of unknown function (DUF2768)
HACLHNLC_03030 1.5e-189 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HACLHNLC_03031 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HACLHNLC_03032 1.1e-104 yphA
HACLHNLC_03033 4.7e-08 S YpzI-like protein
HACLHNLC_03034 1.5e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HACLHNLC_03035 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HACLHNLC_03036 1.6e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HACLHNLC_03037 1.4e-12 S Family of unknown function (DUF5359)
HACLHNLC_03038 1.3e-61 ypfA M Flagellar protein YcgR
HACLHNLC_03039 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HACLHNLC_03040 4.2e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HACLHNLC_03041 9.2e-121 prsW S Involved in the degradation of specific anti-sigma factors
HACLHNLC_03042 4.5e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HACLHNLC_03043 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HACLHNLC_03044 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HACLHNLC_03045 1.6e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
HACLHNLC_03046 5.7e-85 ypbF S Protein of unknown function (DUF2663)
HACLHNLC_03047 3.4e-74 ypbE M Lysin motif
HACLHNLC_03048 2.2e-99 ypbD S metal-dependent membrane protease
HACLHNLC_03049 5.2e-270 recQ 3.6.4.12 L DNA helicase
HACLHNLC_03050 2.4e-195 ypbB 5.1.3.1 S protein conserved in bacteria
HACLHNLC_03051 3.6e-41 fer C Ferredoxin
HACLHNLC_03052 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HACLHNLC_03053 2.8e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HACLHNLC_03054 7e-198 rsiX
HACLHNLC_03055 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HACLHNLC_03056 0.0 resE 2.7.13.3 T Histidine kinase
HACLHNLC_03057 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACLHNLC_03058 1.9e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HACLHNLC_03059 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HACLHNLC_03060 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HACLHNLC_03061 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HACLHNLC_03062 2.2e-88 spmB S Spore maturation protein
HACLHNLC_03063 2e-103 spmA S Spore maturation protein
HACLHNLC_03064 5e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HACLHNLC_03065 3.8e-93 ypuI S Protein of unknown function (DUF3907)
HACLHNLC_03066 5.1e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HACLHNLC_03067 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HACLHNLC_03069 8.4e-93 ypuF S Domain of unknown function (DUF309)
HACLHNLC_03070 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HACLHNLC_03071 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HACLHNLC_03072 2.7e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HACLHNLC_03073 2.2e-111 ribE 2.5.1.9 H Riboflavin synthase
HACLHNLC_03074 2.8e-210 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HACLHNLC_03075 1.7e-49 ypuD
HACLHNLC_03076 1.3e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HACLHNLC_03077 8.2e-82 ccdC1 O Protein of unknown function (DUF1453)
HACLHNLC_03078 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HACLHNLC_03079 6e-155 ypuA S Secreted protein
HACLHNLC_03080 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HACLHNLC_03081 7.1e-270 spoVAF EG Stage V sporulation protein AF
HACLHNLC_03082 1.8e-110 spoVAEA S stage V sporulation protein
HACLHNLC_03083 3.8e-57 spoVAEB S stage V sporulation protein
HACLHNLC_03084 5e-190 spoVAD I Stage V sporulation protein AD
HACLHNLC_03085 6e-79 spoVAC S stage V sporulation protein AC
HACLHNLC_03086 3.9e-60 spoVAB S Stage V sporulation protein AB
HACLHNLC_03087 3.7e-111 spoVAA S Stage V sporulation protein AA
HACLHNLC_03088 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACLHNLC_03089 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HACLHNLC_03090 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HACLHNLC_03091 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HACLHNLC_03092 6.4e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HACLHNLC_03093 6.7e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HACLHNLC_03094 3.7e-165 xerD L recombinase XerD
HACLHNLC_03095 3.7e-37 S Protein of unknown function (DUF4227)
HACLHNLC_03096 1.9e-80 fur P Belongs to the Fur family
HACLHNLC_03097 7.2e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HACLHNLC_03099 1.7e-34 yqkK
HACLHNLC_03100 5.7e-22
HACLHNLC_03101 7.7e-244 mleA 1.1.1.38 C malic enzyme
HACLHNLC_03102 1.2e-239 mleN C Na H antiporter
HACLHNLC_03103 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HACLHNLC_03104 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
HACLHNLC_03105 3.5e-58 ansR K Transcriptional regulator
HACLHNLC_03106 1.4e-217 yqxK 3.6.4.12 L DNA helicase
HACLHNLC_03107 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HACLHNLC_03109 2.2e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HACLHNLC_03111 4.3e-177 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HACLHNLC_03112 3.2e-39 yqkC S Protein of unknown function (DUF2552)
HACLHNLC_03113 7.7e-61 yqkB S Belongs to the HesB IscA family
HACLHNLC_03114 1.1e-175 yqkA K GrpB protein
HACLHNLC_03115 4.7e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HACLHNLC_03116 3.3e-88 yqjY K acetyltransferase
HACLHNLC_03117 2.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HACLHNLC_03118 7.6e-58 S YolD-like protein
HACLHNLC_03120 6e-186 yueF S transporter activity
HACLHNLC_03122 6.6e-74 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HACLHNLC_03123 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HACLHNLC_03124 2.8e-257 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HACLHNLC_03125 1.9e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HACLHNLC_03126 1.3e-176 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HACLHNLC_03127 2.1e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HACLHNLC_03128 9.7e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HACLHNLC_03129 2.1e-238 pksG 2.3.3.10 I synthase
HACLHNLC_03130 8.9e-220 eryK 1.14.13.154 C Cytochrome P450
HACLHNLC_03131 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HACLHNLC_03132 0.0 Q Polyketide synthase of type I
HACLHNLC_03133 0.0 pfaA Q Polyketide synthase of type I
HACLHNLC_03134 0.0 pksJ Q Polyketide synthase of type I
HACLHNLC_03135 9.3e-220 glcP G Major Facilitator Superfamily
HACLHNLC_03136 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HACLHNLC_03137 2.5e-180 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
HACLHNLC_03138 4.2e-200 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
HACLHNLC_03139 1.9e-224 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HACLHNLC_03140 9.7e-175 ybaS 1.1.1.58 S Na -dependent transporter
HACLHNLC_03141 2.8e-102 ybbA S Putative esterase
HACLHNLC_03142 8e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACLHNLC_03143 6.2e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HACLHNLC_03144 1.1e-170 feuA P Iron-uptake system-binding protein
HACLHNLC_03145 2.2e-311 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HACLHNLC_03146 7.8e-238 ybbC 3.2.1.52 S protein conserved in bacteria
HACLHNLC_03147 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HACLHNLC_03148 1.4e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HACLHNLC_03149 1.1e-237 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACLHNLC_03150 2e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HACLHNLC_03151 1.1e-86 ybbJ J acetyltransferase
HACLHNLC_03152 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HACLHNLC_03158 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HACLHNLC_03159 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HACLHNLC_03160 1.3e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HACLHNLC_03161 2.6e-224 ybbR S protein conserved in bacteria
HACLHNLC_03162 4.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HACLHNLC_03163 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HACLHNLC_03164 1.9e-06
HACLHNLC_03165 4.4e-97 ybdN
HACLHNLC_03166 4.9e-133 ybdO S Domain of unknown function (DUF4885)
HACLHNLC_03167 4.3e-163 dkgB S Aldo/keto reductase family
HACLHNLC_03168 1e-93 yxaC M effector of murein hydrolase
HACLHNLC_03169 6.9e-52 S LrgA family
HACLHNLC_03170 8.8e-72 yxaD K helix_turn_helix multiple antibiotic resistance protein
HACLHNLC_03172 8.9e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HACLHNLC_03173 9.4e-95 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HACLHNLC_03174 1.1e-201 T COG4585 Signal transduction histidine kinase
HACLHNLC_03175 2.3e-108 KT LuxR family transcriptional regulator
HACLHNLC_03176 5.4e-167 V COG1131 ABC-type multidrug transport system, ATPase component
HACLHNLC_03177 4.9e-205 V COG0842 ABC-type multidrug transport system, permease component
HACLHNLC_03178 2.9e-199 V ABC-2 family transporter protein
HACLHNLC_03179 5.8e-25
HACLHNLC_03180 4.5e-77 S Domain of unknown function (DUF4879)
HACLHNLC_03181 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HACLHNLC_03182 1.4e-106 yqeB
HACLHNLC_03183 9.2e-40 ybyB
HACLHNLC_03184 1.2e-291 ybeC E amino acid
HACLHNLC_03185 1e-53
HACLHNLC_03186 3.4e-15 S Protein of unknown function (DUF2651)
HACLHNLC_03187 2.4e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HACLHNLC_03188 1.7e-259 glpT G -transporter
HACLHNLC_03189 1.3e-16 S Protein of unknown function (DUF2651)
HACLHNLC_03190 1.5e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HACLHNLC_03192 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HACLHNLC_03193 1.3e-30
HACLHNLC_03194 1.8e-81 K Helix-turn-helix XRE-family like proteins
HACLHNLC_03195 8.6e-201 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HACLHNLC_03196 6.2e-213 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HACLHNLC_03197 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HACLHNLC_03198 1.9e-86 ybfM S SNARE associated Golgi protein
HACLHNLC_03199 1.9e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HACLHNLC_03200 8e-42 ybfN
HACLHNLC_03201 2.3e-192 yceA S Belongs to the UPF0176 family
HACLHNLC_03202 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HACLHNLC_03203 8.6e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HACLHNLC_03204 6.9e-257 mmuP E amino acid
HACLHNLC_03205 2.8e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HACLHNLC_03206 9.3e-259 agcS E Sodium alanine symporter
HACLHNLC_03207 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
HACLHNLC_03208 8.5e-211 phoQ 2.7.13.3 T Histidine kinase
HACLHNLC_03209 9.1e-170 glnL T Regulator
HACLHNLC_03210 2.7e-29 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HACLHNLC_03211 4.5e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HACLHNLC_03212 2.4e-110 ydfN C nitroreductase
HACLHNLC_03213 3.2e-183 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HACLHNLC_03214 1.5e-62 mhqP S DoxX
HACLHNLC_03215 4.1e-56 traF CO Thioredoxin
HACLHNLC_03216 5.6e-62 ycbP S Protein of unknown function (DUF2512)
HACLHNLC_03217 5.1e-80 sleB 3.5.1.28 M Cell wall
HACLHNLC_03218 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HACLHNLC_03219 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HACLHNLC_03220 1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HACLHNLC_03221 1.6e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HACLHNLC_03222 4.2e-206 ycbU E Selenocysteine lyase
HACLHNLC_03223 1e-241 lmrB EGP the major facilitator superfamily
HACLHNLC_03224 1.2e-100 yxaF K Transcriptional regulator
HACLHNLC_03225 1.1e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HACLHNLC_03226 1.3e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HACLHNLC_03227 5.4e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
HACLHNLC_03228 6.2e-171 yccK C Aldo keto reductase
HACLHNLC_03229 1e-176 ycdA S Domain of unknown function (DUF5105)
HACLHNLC_03230 1.2e-258 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HACLHNLC_03231 7.7e-263 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HACLHNLC_03232 4e-92 cwlK M D-alanyl-D-alanine carboxypeptidase
HACLHNLC_03233 6e-189 S response regulator aspartate phosphatase
HACLHNLC_03234 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
HACLHNLC_03235 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HACLHNLC_03236 7.9e-164 adcA P Belongs to the bacterial solute-binding protein 9 family
HACLHNLC_03237 5.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HACLHNLC_03238 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HACLHNLC_03239 3.3e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HACLHNLC_03240 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HACLHNLC_03241 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
HACLHNLC_03242 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
HACLHNLC_03243 9.7e-138 terC P Protein of unknown function (DUF475)
HACLHNLC_03244 0.0 yceG S Putative component of 'biosynthetic module'
HACLHNLC_03245 5.1e-193 yceH P Belongs to the TelA family
HACLHNLC_03246 1.8e-215 naiP P Uncharacterised MFS-type transporter YbfB
HACLHNLC_03247 4.3e-228 proV 3.6.3.32 E glycine betaine
HACLHNLC_03248 1.6e-138 opuAB P glycine betaine
HACLHNLC_03249 3.1e-164 opuAC E glycine betaine
HACLHNLC_03250 3.1e-209 amhX S amidohydrolase
HACLHNLC_03251 4e-230 ycgA S Membrane
HACLHNLC_03252 3.1e-81 ycgB
HACLHNLC_03253 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HACLHNLC_03254 5.7e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HACLHNLC_03255 1.5e-259 mdr EGP Major facilitator Superfamily
HACLHNLC_03256 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
HACLHNLC_03257 4.7e-114 ycgF E Lysine exporter protein LysE YggA
HACLHNLC_03258 2.9e-150 yqcI S YqcI/YcgG family
HACLHNLC_03259 8.3e-246 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HACLHNLC_03260 7.6e-114 ycgI S Domain of unknown function (DUF1989)
HACLHNLC_03261 1.8e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HACLHNLC_03263 1.9e-136 4.2.1.118 G Xylose isomerase-like TIM barrel
HACLHNLC_03264 9.1e-221 G COG0477 Permeases of the major facilitator superfamily
HACLHNLC_03265 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HACLHNLC_03266 4.5e-185 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HACLHNLC_03267 5.9e-143 ycgL S Predicted nucleotidyltransferase
HACLHNLC_03268 2.3e-170 ycgM E Proline dehydrogenase
HACLHNLC_03269 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HACLHNLC_03270 2.9e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HACLHNLC_03271 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HACLHNLC_03272 3.5e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HACLHNLC_03273 9.9e-277 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HACLHNLC_03274 3.9e-56 nirD 1.7.1.15 P Nitrite reductase
HACLHNLC_03275 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HACLHNLC_03276 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HACLHNLC_03277 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HACLHNLC_03278 1.2e-222 nasA P COG2223 Nitrate nitrite transporter
HACLHNLC_03279 1.6e-227 yciC S GTPases (G3E family)
HACLHNLC_03280 4.6e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HACLHNLC_03281 4.7e-73 yckC S membrane
HACLHNLC_03282 2.2e-51 S Protein of unknown function (DUF2680)
HACLHNLC_03283 2.2e-34 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HACLHNLC_03284 2.9e-69 nin S Competence protein J (ComJ)
HACLHNLC_03285 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
HACLHNLC_03286 1.1e-93 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HACLHNLC_03287 2.8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HACLHNLC_03288 6.3e-63 hxlR K transcriptional
HACLHNLC_03289 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_03290 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_03291 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HACLHNLC_03292 3.4e-140 srfAD Q thioesterase
HACLHNLC_03293 2.7e-249 bamJ E Aminotransferase class I and II
HACLHNLC_03294 3.8e-64 S YcxB-like protein
HACLHNLC_03295 1.3e-168 ycxC EG EamA-like transporter family
HACLHNLC_03296 8.2e-246 ycxD K GntR family transcriptional regulator
HACLHNLC_03297 6.5e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HACLHNLC_03298 2.8e-111 yczE S membrane
HACLHNLC_03299 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HACLHNLC_03300 1.4e-119 tcyB P COG0765 ABC-type amino acid transport system, permease component
HACLHNLC_03301 1.4e-142 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HACLHNLC_03302 1.5e-158 bsdA K LysR substrate binding domain
HACLHNLC_03303 7.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HACLHNLC_03304 2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HACLHNLC_03305 2e-38 bsdD 4.1.1.61 S response to toxic substance
HACLHNLC_03306 2.2e-76 yclD
HACLHNLC_03307 4.7e-67 yshE S membrane
HACLHNLC_03308 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HACLHNLC_03309 0.0 polX L COG1796 DNA polymerase IV (family X)
HACLHNLC_03310 1.6e-83 cvpA S membrane protein, required for colicin V production
HACLHNLC_03311 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HACLHNLC_03312 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HACLHNLC_03313 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HACLHNLC_03314 1.2e-194 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HACLHNLC_03315 2e-132 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HACLHNLC_03316 2e-32 sspI S Belongs to the SspI family
HACLHNLC_03317 2.4e-206 ysfB KT regulator
HACLHNLC_03318 8.2e-260 glcD 1.1.3.15 C FAD binding domain
HACLHNLC_03319 3.4e-255 glcF C Glycolate oxidase
HACLHNLC_03320 0.0 cstA T Carbon starvation protein
HACLHNLC_03321 3.9e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HACLHNLC_03322 1.2e-144 araQ G transport system permease
HACLHNLC_03323 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
HACLHNLC_03324 1.8e-253 araN G carbohydrate transport
HACLHNLC_03325 1.3e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HACLHNLC_03326 1.2e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HACLHNLC_03327 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HACLHNLC_03328 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HACLHNLC_03329 3.4e-296 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HACLHNLC_03330 4.4e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HACLHNLC_03331 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
HACLHNLC_03332 1.7e-66 ysdB S Sigma-w pathway protein YsdB
HACLHNLC_03333 7e-43 ysdA S Membrane
HACLHNLC_03334 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HACLHNLC_03335 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HACLHNLC_03336 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HACLHNLC_03337 1.1e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HACLHNLC_03338 9.1e-40 lrgA S effector of murein hydrolase LrgA
HACLHNLC_03339 1.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
HACLHNLC_03340 0.0 lytS 2.7.13.3 T Histidine kinase
HACLHNLC_03341 1e-150 ysaA S HAD-hyrolase-like
HACLHNLC_03342 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HACLHNLC_03343 4.4e-152 ytxC S YtxC-like family
HACLHNLC_03344 3.3e-107 ytxB S SNARE associated Golgi protein
HACLHNLC_03345 9.5e-172 dnaI L Primosomal protein DnaI
HACLHNLC_03346 5.9e-250 dnaB L Membrane attachment protein
HACLHNLC_03347 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HACLHNLC_03348 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HACLHNLC_03349 8.8e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HACLHNLC_03350 2e-67 ytcD K Transcriptional regulator
HACLHNLC_03351 1.7e-205 ytbD EGP Major facilitator Superfamily
HACLHNLC_03352 7.6e-160 ytbE S reductase
HACLHNLC_03353 5.2e-99 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HACLHNLC_03354 9.5e-107 ytaF P Probably functions as a manganese efflux pump
HACLHNLC_03355 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HACLHNLC_03356 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HACLHNLC_03357 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HACLHNLC_03358 3.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACLHNLC_03359 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HACLHNLC_03360 3.1e-242 icd 1.1.1.42 C isocitrate
HACLHNLC_03361 3.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HACLHNLC_03362 2.7e-52
HACLHNLC_03363 1.1e-47 yjdF S Protein of unknown function (DUF2992)
HACLHNLC_03364 2.5e-72 yeaL S membrane
HACLHNLC_03365 2.4e-193 ytvI S sporulation integral membrane protein YtvI
HACLHNLC_03366 2.1e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HACLHNLC_03367 6.4e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HACLHNLC_03368 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HACLHNLC_03369 2.4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HACLHNLC_03370 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HACLHNLC_03371 2.6e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HACLHNLC_03372 0.0 dnaE 2.7.7.7 L DNA polymerase
HACLHNLC_03373 3.2e-56 ytrH S Sporulation protein YtrH
HACLHNLC_03374 5.1e-87 ytrI
HACLHNLC_03375 4.4e-23
HACLHNLC_03376 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HACLHNLC_03377 1.5e-46 ytpI S YtpI-like protein
HACLHNLC_03378 2.8e-238 ytoI K transcriptional regulator containing CBS domains
HACLHNLC_03379 1.1e-129 ytkL S Belongs to the UPF0173 family
HACLHNLC_03380 4.5e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HACLHNLC_03382 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
HACLHNLC_03383 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HACLHNLC_03384 2.3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HACLHNLC_03385 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HACLHNLC_03386 3.7e-182 ytxK 2.1.1.72 L DNA methylase
HACLHNLC_03387 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HACLHNLC_03388 1.6e-60 ytfJ S Sporulation protein YtfJ
HACLHNLC_03389 1.4e-108 ytfI S Protein of unknown function (DUF2953)
HACLHNLC_03390 4.5e-88 yteJ S RDD family
HACLHNLC_03391 1.1e-181 sppA OU signal peptide peptidase SppA
HACLHNLC_03392 5.7e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HACLHNLC_03393 0.0 ytcJ S amidohydrolase
HACLHNLC_03394 1.6e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HACLHNLC_03395 3.9e-31 sspB S spore protein
HACLHNLC_03396 3.9e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HACLHNLC_03397 2.7e-208 iscS2 2.8.1.7 E Cysteine desulfurase
HACLHNLC_03398 3.1e-240 braB E Component of the transport system for branched-chain amino acids
HACLHNLC_03399 1.1e-263 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HACLHNLC_03400 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HACLHNLC_03401 7.7e-109 yttP K Transcriptional regulator
HACLHNLC_03402 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
HACLHNLC_03403 5.6e-282 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HACLHNLC_03404 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HACLHNLC_03405 3.5e-255 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HACLHNLC_03406 6.4e-99 yokH G SMI1 / KNR4 family
HACLHNLC_03407 2.9e-10 V HNH endonuclease
HACLHNLC_03408 8.2e-59 UW Hep Hag repeat protein
HACLHNLC_03409 4.1e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HACLHNLC_03410 2.5e-09
HACLHNLC_03411 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HACLHNLC_03413 3.5e-140 E GDSL-like Lipase/Acylhydrolase family
HACLHNLC_03414 1.9e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HACLHNLC_03415 5.7e-149 K Transcriptional regulator
HACLHNLC_03416 2.6e-124 azlC E AzlC protein
HACLHNLC_03417 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
HACLHNLC_03418 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HACLHNLC_03419 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HACLHNLC_03420 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HACLHNLC_03421 9.3e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
HACLHNLC_03422 1.9e-230 acuC BQ histone deacetylase
HACLHNLC_03423 3.7e-120 motS N Flagellar motor protein
HACLHNLC_03424 2.5e-144 motA N flagellar motor
HACLHNLC_03425 6.4e-182 ccpA K catabolite control protein A
HACLHNLC_03426 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HACLHNLC_03427 4.5e-44 ytxJ O Protein of unknown function (DUF2847)
HACLHNLC_03428 1.7e-16 ytxH S COG4980 Gas vesicle protein
HACLHNLC_03429 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HACLHNLC_03430 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HACLHNLC_03431 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HACLHNLC_03432 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HACLHNLC_03433 1.4e-147 ytpQ S Belongs to the UPF0354 family
HACLHNLC_03434 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HACLHNLC_03435 1.7e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HACLHNLC_03436 1.4e-69 T HPP family
HACLHNLC_03437 3.7e-65 S Putative stress-induced transcription regulator
HACLHNLC_03438 2.2e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HACLHNLC_03439 1.7e-51 ytzB S small secreted protein
HACLHNLC_03440 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HACLHNLC_03441 8.7e-164 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HACLHNLC_03442 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HACLHNLC_03443 1.3e-44 ytzH S YtzH-like protein
HACLHNLC_03444 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
HACLHNLC_03445 2.6e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HACLHNLC_03446 1.8e-170 ytlQ
HACLHNLC_03447 5.2e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HACLHNLC_03448 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HACLHNLC_03449 2.1e-268 pepV 3.5.1.18 E Dipeptidase
HACLHNLC_03450 2.6e-228 pbuO S permease
HACLHNLC_03451 2.3e-215 ythQ U Bacterial ABC transporter protein EcsB
HACLHNLC_03452 7.5e-129 ythP V ABC transporter
HACLHNLC_03453 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HACLHNLC_03454 8.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HACLHNLC_03455 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HACLHNLC_03456 3.3e-236 ytfP S HI0933-like protein
HACLHNLC_03457 6.4e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HACLHNLC_03458 9e-26 yteV S Sporulation protein Cse60
HACLHNLC_03459 1.8e-184 msmR K Transcriptional regulator
HACLHNLC_03460 4.4e-244 msmE G Bacterial extracellular solute-binding protein
HACLHNLC_03461 5.3e-167 amyD G Binding-protein-dependent transport system inner membrane component
HACLHNLC_03462 9e-142 amyC P ABC transporter (permease)
HACLHNLC_03463 2.9e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HACLHNLC_03464 2.2e-47 M Acetyltransferase (GNAT) domain
HACLHNLC_03465 4.3e-26 M Acetyltransferase (GNAT) domain
HACLHNLC_03466 1.8e-50 ytwF P Sulfurtransferase
HACLHNLC_03467 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HACLHNLC_03468 1.2e-52 ytvB S Protein of unknown function (DUF4257)
HACLHNLC_03469 3.4e-138 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HACLHNLC_03470 2.2e-205 yttB EGP Major facilitator Superfamily
HACLHNLC_03471 7.2e-127 ywaF S Integral membrane protein
HACLHNLC_03472 0.0 bceB V ABC transporter (permease)
HACLHNLC_03473 9.8e-135 bceA V ABC transporter, ATP-binding protein
HACLHNLC_03474 1e-171 T PhoQ Sensor
HACLHNLC_03475 2e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HACLHNLC_03476 1.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HACLHNLC_03477 2.2e-125 ytrE V ABC transporter, ATP-binding protein
HACLHNLC_03478 2.9e-147
HACLHNLC_03479 6.3e-166 P ABC-2 family transporter protein
HACLHNLC_03480 6.5e-171 S ABC-2 family transporter protein
HACLHNLC_03481 3.8e-162 ytrB P abc transporter atp-binding protein
HACLHNLC_03482 3.9e-66 ytrA K GntR family transcriptional regulator
HACLHNLC_03484 7.4e-40 ytzC S Protein of unknown function (DUF2524)
HACLHNLC_03485 0.0 IQ AMP-binding enzyme
HACLHNLC_03486 6.1e-202 K helix_turn_helix, Arsenical Resistance Operon Repressor
HACLHNLC_03487 0.0 Q Polyketide synthase of type I
HACLHNLC_03488 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HACLHNLC_03490 3.5e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HACLHNLC_03493 5.7e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HACLHNLC_03494 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HACLHNLC_03495 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
HACLHNLC_03496 1e-304 recN L May be involved in recombinational repair of damaged DNA
HACLHNLC_03497 3.9e-78 argR K Regulates arginine biosynthesis genes
HACLHNLC_03498 7.3e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HACLHNLC_03499 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HACLHNLC_03500 8.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HACLHNLC_03501 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HACLHNLC_03502 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HACLHNLC_03503 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HACLHNLC_03504 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HACLHNLC_03505 8.1e-67 yqhY S protein conserved in bacteria
HACLHNLC_03506 2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HACLHNLC_03507 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HACLHNLC_03508 2.5e-62 spoIIIAH S SpoIIIAH-like protein
HACLHNLC_03509 7.7e-118 spoIIIAG S stage III sporulation protein AG
HACLHNLC_03510 2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HACLHNLC_03511 6.3e-200 spoIIIAE S stage III sporulation protein AE
HACLHNLC_03512 2.5e-41 spoIIIAD S Stage III sporulation protein AD
HACLHNLC_03513 7.6e-29 spoIIIAC S stage III sporulation protein AC
HACLHNLC_03514 1.2e-83 spoIIIAB S Stage III sporulation protein
HACLHNLC_03515 1.1e-172 spoIIIAA S stage III sporulation protein AA
HACLHNLC_03516 1.8e-36 yqhV S Protein of unknown function (DUF2619)
HACLHNLC_03517 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HACLHNLC_03518 7.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HACLHNLC_03519 3.7e-88 yqhR S Conserved membrane protein YqhR
HACLHNLC_03520 2e-172 yqhQ S Protein of unknown function (DUF1385)
HACLHNLC_03521 7.6e-62 yqhP
HACLHNLC_03522 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
HACLHNLC_03523 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HACLHNLC_03524 3.7e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HACLHNLC_03525 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
HACLHNLC_03526 9.8e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HACLHNLC_03527 3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HACLHNLC_03528 1e-209 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HACLHNLC_03529 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HACLHNLC_03530 9.3e-152 yqhG S Bacterial protein YqhG of unknown function
HACLHNLC_03531 3.4e-22 sinI S Anti-repressor SinI
HACLHNLC_03532 7.8e-55 sinR K transcriptional
HACLHNLC_03533 7.3e-141 tasA S Cell division protein FtsN
HACLHNLC_03534 1.7e-70 sipW 3.4.21.89 U Signal peptidase
HACLHNLC_03535 1.6e-120 yqxM
HACLHNLC_03536 2.4e-53 yqzG S Protein of unknown function (DUF3889)
HACLHNLC_03537 2.3e-26 yqzE S YqzE-like protein
HACLHNLC_03538 8e-61 S ComG operon protein 7
HACLHNLC_03539 1.7e-76 comGF U Putative Competence protein ComGF
HACLHNLC_03540 2e-20 comGE
HACLHNLC_03541 1.6e-73 gspH NU Tfp pilus assembly protein FimT
HACLHNLC_03542 8.9e-50 comGC U Required for transformation and DNA binding
HACLHNLC_03543 2.4e-184 comGB NU COG1459 Type II secretory pathway, component PulF
HACLHNLC_03544 1.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HACLHNLC_03545 1.2e-185 corA P Mg2 transporter protein
HACLHNLC_03546 6.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HACLHNLC_03547 1.6e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HACLHNLC_03549 7.8e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HACLHNLC_03550 3.1e-37 yqgY S Protein of unknown function (DUF2626)
HACLHNLC_03551 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HACLHNLC_03552 1.2e-19 yqgW S Protein of unknown function (DUF2759)
HACLHNLC_03553 6.9e-50 yqgV S Thiamine-binding protein
HACLHNLC_03554 1.9e-197 yqgU
HACLHNLC_03555 9.6e-219 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HACLHNLC_03556 2.6e-180 glcK 2.7.1.2 G Glucokinase
HACLHNLC_03557 7e-210 nhaC C Na H antiporter
HACLHNLC_03558 4e-07 yqgO
HACLHNLC_03559 1.6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HACLHNLC_03560 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HACLHNLC_03561 1.2e-50 yqzD
HACLHNLC_03562 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HACLHNLC_03563 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HACLHNLC_03564 1.6e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HACLHNLC_03565 4.1e-156 pstA P Phosphate transport system permease
HACLHNLC_03566 5.2e-154 pstC P probably responsible for the translocation of the substrate across the membrane
HACLHNLC_03567 1.7e-157 pstS P Phosphate
HACLHNLC_03568 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HACLHNLC_03569 2.6e-228 yqgE EGP Major facilitator superfamily
HACLHNLC_03570 1.5e-114 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HACLHNLC_03571 3e-76 yqgC S protein conserved in bacteria
HACLHNLC_03572 5.7e-130 yqgB S Protein of unknown function (DUF1189)
HACLHNLC_03573 1e-45 yqfZ M LysM domain
HACLHNLC_03574 1.5e-200 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HACLHNLC_03575 2.3e-52 yqfX S membrane
HACLHNLC_03576 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HACLHNLC_03577 2.9e-72 zur P Belongs to the Fur family
HACLHNLC_03578 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HACLHNLC_03579 9.3e-37 yqfT S Protein of unknown function (DUF2624)
HACLHNLC_03580 1.7e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HACLHNLC_03581 1.2e-247 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HACLHNLC_03582 6.2e-51 yqfQ S YqfQ-like protein
HACLHNLC_03583 3.8e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HACLHNLC_03584 4.3e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HACLHNLC_03585 2.2e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
HACLHNLC_03586 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
HACLHNLC_03587 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HACLHNLC_03588 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HACLHNLC_03589 1.8e-87 yaiI S Belongs to the UPF0178 family
HACLHNLC_03590 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HACLHNLC_03591 4.5e-112 ccpN K CBS domain
HACLHNLC_03592 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HACLHNLC_03593 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HACLHNLC_03594 4.1e-144 recO L Involved in DNA repair and RecF pathway recombination
HACLHNLC_03595 1.8e-16 S YqzL-like protein
HACLHNLC_03596 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HACLHNLC_03597 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HACLHNLC_03598 1.7e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HACLHNLC_03599 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HACLHNLC_03600 0.0 yqfF S membrane-associated HD superfamily hydrolase
HACLHNLC_03601 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
HACLHNLC_03602 6.1e-216 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HACLHNLC_03603 9.3e-46 yqfC S sporulation protein YqfC
HACLHNLC_03604 9e-40 yqfB
HACLHNLC_03605 5.8e-119 yqfA S UPF0365 protein
HACLHNLC_03606 2e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HACLHNLC_03607 1.2e-68 yqeY S Yqey-like protein
HACLHNLC_03608 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HACLHNLC_03609 6.6e-157 yqeW P COG1283 Na phosphate symporter
HACLHNLC_03610 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HACLHNLC_03611 1.4e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HACLHNLC_03612 2.3e-173 prmA J Methylates ribosomal protein L11
HACLHNLC_03613 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HACLHNLC_03614 0.0 dnaK O Heat shock 70 kDa protein
HACLHNLC_03615 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HACLHNLC_03616 2.3e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HACLHNLC_03617 5.3e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HACLHNLC_03618 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HACLHNLC_03619 3.8e-54 yqxA S Protein of unknown function (DUF3679)
HACLHNLC_03620 4.1e-220 spoIIP M stage II sporulation protein P
HACLHNLC_03621 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HACLHNLC_03622 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
HACLHNLC_03623 1.1e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
HACLHNLC_03624 0.0 comEC S Competence protein ComEC
HACLHNLC_03625 8e-105 comEB 3.5.4.12 F ComE operon protein 2
HACLHNLC_03626 3.6e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HACLHNLC_03627 2.7e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HACLHNLC_03628 9.3e-138 yqeM Q Methyltransferase
HACLHNLC_03629 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HACLHNLC_03630 2.1e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HACLHNLC_03631 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HACLHNLC_03632 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HACLHNLC_03633 2.1e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HACLHNLC_03634 3.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HACLHNLC_03635 2e-94 yqeG S hydrolase of the HAD superfamily
HACLHNLC_03637 5e-139 yqeF E GDSL-like Lipase/Acylhydrolase
HACLHNLC_03638 4e-141 3.5.1.104 G Polysaccharide deacetylase
HACLHNLC_03639 4.2e-107 yqeD S SNARE associated Golgi protein
HACLHNLC_03640 1.3e-26 2.3.1.57 K Acetyltransferase (GNAT) domain
HACLHNLC_03641 8.2e-219 EGP Major facilitator Superfamily
HACLHNLC_03642 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HACLHNLC_03643 2.2e-159 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HACLHNLC_03644 2e-89 K Transcriptional regulator PadR-like family
HACLHNLC_03645 3e-69 psiE S Belongs to the PsiE family
HACLHNLC_03646 4e-237 yrkQ T Histidine kinase
HACLHNLC_03647 4.2e-124 T Transcriptional regulator
HACLHNLC_03648 1.9e-220 yrkO P Protein of unknown function (DUF418)
HACLHNLC_03650 3.8e-104 yrkN K Acetyltransferase (GNAT) family
HACLHNLC_03651 1.5e-97 adk 2.7.4.3 F adenylate kinase activity
HACLHNLC_03652 1e-31 yyaR K acetyltransferase
HACLHNLC_03653 7.2e-71 tetL EGP Major facilitator Superfamily
HACLHNLC_03654 3.7e-80 yyaR K Acetyltransferase (GNAT) domain
HACLHNLC_03655 1.5e-91 yrdA S DinB family
HACLHNLC_03657 2.9e-145 S hydrolase
HACLHNLC_03658 7.8e-146 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HACLHNLC_03659 1.6e-129 glvR K Helix-turn-helix domain, rpiR family
HACLHNLC_03660 7.9e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
HACLHNLC_03661 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HACLHNLC_03662 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HACLHNLC_03663 4.1e-183 romA S Beta-lactamase superfamily domain
HACLHNLC_03664 1.1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HACLHNLC_03665 3.1e-164 yybE K Transcriptional regulator
HACLHNLC_03666 1e-213 ynfM EGP Major facilitator Superfamily
HACLHNLC_03667 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HACLHNLC_03668 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HACLHNLC_03669 3.9e-93 yrhH Q methyltransferase
HACLHNLC_03671 8e-143 focA P Formate nitrite
HACLHNLC_03672 1.7e-60 yrhF S Uncharacterized conserved protein (DUF2294)
HACLHNLC_03673 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HACLHNLC_03674 2.2e-79 yrhD S Protein of unknown function (DUF1641)
HACLHNLC_03675 1.8e-34 yrhC S YrhC-like protein
HACLHNLC_03676 2.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HACLHNLC_03677 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HACLHNLC_03678 8e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HACLHNLC_03679 3.3e-115 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HACLHNLC_03680 4.1e-27 yrzA S Protein of unknown function (DUF2536)
HACLHNLC_03681 4e-287 yfiU EGP Major facilitator Superfamily
HACLHNLC_03682 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
HACLHNLC_03683 1.5e-45 yrdF K ribonuclease inhibitor
HACLHNLC_03684 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
HACLHNLC_03685 1.8e-177 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HACLHNLC_03686 2.5e-112 1.6.5.2 S NADPH-dependent FMN reductase
HACLHNLC_03687 8.6e-96 padR K transcriptional
HACLHNLC_03688 7.2e-167 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HACLHNLC_03689 8.6e-194 S Oxidoreductase
HACLHNLC_03690 2.3e-157 G Xylose isomerase
HACLHNLC_03691 1.2e-192 iolT EGP Major facilitator Superfamily
HACLHNLC_03692 4.1e-98 K AraC-like ligand binding domain
HACLHNLC_03693 2.6e-160 yfiE 1.13.11.2 S glyoxalase
HACLHNLC_03694 7e-63 mhqP S DoxX
HACLHNLC_03695 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HACLHNLC_03696 1.7e-310 yfiB3 V ABC transporter
HACLHNLC_03697 0.0 yobO M COG5434 Endopolygalacturonase
HACLHNLC_03698 3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACLHNLC_03699 1.7e-139 glvR F Helix-turn-helix domain, rpiR family
HACLHNLC_03700 7.6e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HACLHNLC_03701 4.2e-15 sspH S Belongs to the SspH family
HACLHNLC_03702 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HACLHNLC_03703 1.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HACLHNLC_03704 2.9e-213 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HACLHNLC_03705 2.8e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HACLHNLC_03706 1.1e-189 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HACLHNLC_03707 6.8e-89 yfjM S Psort location Cytoplasmic, score
HACLHNLC_03708 1.1e-191 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HACLHNLC_03709 1.2e-48 S YfzA-like protein
HACLHNLC_03710 4.3e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HACLHNLC_03711 8.3e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HACLHNLC_03712 8.5e-184 corA P Mediates influx of magnesium ions
HACLHNLC_03713 1.4e-33
HACLHNLC_03714 4e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HACLHNLC_03715 9e-155 pdaA G deacetylase
HACLHNLC_03716 4.9e-27 yfjT
HACLHNLC_03717 5.6e-219 yfkA S YfkB-like domain
HACLHNLC_03718 2.8e-146 yfkC M Mechanosensitive ion channel
HACLHNLC_03719 1.2e-143 yfkD S YfkD-like protein
HACLHNLC_03720 1.3e-185 cax P COG0387 Ca2 H antiporter
HACLHNLC_03721 6.5e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HACLHNLC_03723 6.8e-145 yihY S Belongs to the UPF0761 family
HACLHNLC_03724 3.5e-52 yfkI S gas vesicle protein
HACLHNLC_03725 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HACLHNLC_03726 2.7e-29 yfkK S Belongs to the UPF0435 family
HACLHNLC_03727 5.6e-193 ydiM EGP Major facilitator Superfamily
HACLHNLC_03728 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HACLHNLC_03729 6.9e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HACLHNLC_03730 3e-187 K helix_turn _helix lactose operon repressor
HACLHNLC_03731 1e-90 yfkM 1.11.1.6, 3.5.1.124 S protease
HACLHNLC_03732 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HACLHNLC_03733 2.7e-200 yibE S YibE/F-like protein
HACLHNLC_03734 3.5e-124 yibF S YibE/F-like protein
HACLHNLC_03735 5.8e-123 yfkO C nitroreductase
HACLHNLC_03736 2.6e-129 treR K transcriptional
HACLHNLC_03737 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HACLHNLC_03738 4.3e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HACLHNLC_03739 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
HACLHNLC_03740 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
HACLHNLC_03741 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
HACLHNLC_03742 3.8e-63 yhdN S Domain of unknown function (DUF1992)
HACLHNLC_03743 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HACLHNLC_03744 3.7e-73 yfmQ S Uncharacterised protein from bacillus cereus group
HACLHNLC_03745 8.7e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HACLHNLC_03746 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
HACLHNLC_03747 3.1e-50 yflH S Protein of unknown function (DUF3243)
HACLHNLC_03748 1.6e-18 yflI
HACLHNLC_03749 1.5e-14 yflJ S Protein of unknown function (DUF2639)
HACLHNLC_03750 2.9e-122 yflK S protein conserved in bacteria
HACLHNLC_03751 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HACLHNLC_03752 9.3e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HACLHNLC_03753 8.7e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HACLHNLC_03754 2.5e-226 citM C Citrate transporter
HACLHNLC_03755 1.6e-177 yflP S Tripartite tricarboxylate transporter family receptor
HACLHNLC_03756 1.8e-119 citT T response regulator
HACLHNLC_03757 1.8e-271 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HACLHNLC_03758 6.8e-24 M1-820 Q Collagen triple helix repeat (20 copies)
HACLHNLC_03759 5.6e-23 M1-820 Q Collagen triple helix repeat (20 copies)
HACLHNLC_03761 1.8e-28 Q PFAM Collagen triple helix
HACLHNLC_03762 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
HACLHNLC_03763 7.7e-241 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HACLHNLC_03764 1.3e-57 yflT S Heat induced stress protein YflT
HACLHNLC_03765 2e-24 S Protein of unknown function (DUF3212)
HACLHNLC_03766 1.6e-188 yfmJ S N-terminal domain of oxidoreductase
HACLHNLC_03767 1.5e-50 yfmK 2.3.1.128 K acetyltransferase
HACLHNLC_03768 5.5e-206 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HACLHNLC_03769 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HACLHNLC_03770 8.9e-207 yfmO EGP Major facilitator Superfamily
HACLHNLC_03771 9e-69 yfmP K transcriptional
HACLHNLC_03772 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HACLHNLC_03773 5.5e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HACLHNLC_03774 1.5e-166 IQ Enoyl-(Acyl carrier protein) reductase
HACLHNLC_03775 9.8e-115 yfmS NT chemotaxis protein
HACLHNLC_03776 4.5e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HACLHNLC_03777 3.3e-245 yfnA E amino acid
HACLHNLC_03778 4.4e-217 fsr P COG0477 Permeases of the major facilitator superfamily
HACLHNLC_03779 4e-186 yfnD M Nucleotide-diphospho-sugar transferase
HACLHNLC_03780 3.9e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HACLHNLC_03781 4.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
HACLHNLC_03782 3.5e-171 yfnG 4.2.1.45 M dehydratase
HACLHNLC_03783 5.1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
HACLHNLC_03784 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HACLHNLC_03785 1.6e-146 2.1.1.163, 2.1.1.201 Q methyltransferase
HACLHNLC_03786 1e-111 S CAAX protease self-immunity
HACLHNLC_03787 9.5e-152 sagB C Nitroreductase family
HACLHNLC_03788 5.8e-263 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
HACLHNLC_03789 1.3e-190 S ATP diphosphatase activity
HACLHNLC_03790 9.2e-127
HACLHNLC_03791 7.1e-74 S protein homooligomerization
HACLHNLC_03792 3.7e-126 V ABC-2 type transporter
HACLHNLC_03793 4.1e-164 V ATPases associated with a variety of cellular activities
HACLHNLC_03794 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
HACLHNLC_03796 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HACLHNLC_03797 8.3e-196 yetN S Protein of unknown function (DUF3900)
HACLHNLC_03798 5.8e-208 yetM CH FAD binding domain
HACLHNLC_03799 2.9e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HACLHNLC_03801 1.8e-105 yetJ S Belongs to the BI1 family
HACLHNLC_03802 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
HACLHNLC_03803 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
HACLHNLC_03804 3.4e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HACLHNLC_03805 5.8e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HACLHNLC_03806 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HACLHNLC_03807 8.7e-122 yetF S membrane
HACLHNLC_03809 9.8e-97 yesJ K Acetyltransferase (GNAT) family
HACLHNLC_03810 8.9e-104 cotJC P Spore Coat
HACLHNLC_03811 3.3e-45 cotJB S CotJB protein
HACLHNLC_03812 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
HACLHNLC_03813 1.4e-108 aadK G Streptomycin adenylyltransferase
HACLHNLC_03815 9.4e-127 yeeN K transcriptional regulatory protein
HACLHNLC_03816 1.1e-248 yobL S Bacterial EndoU nuclease
HACLHNLC_03817 9.9e-21 S Colicin immunity protein / pyocin immunity protein
HACLHNLC_03818 3.8e-138 cylB V ABC-2 type transporter
HACLHNLC_03819 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
HACLHNLC_03820 8.1e-311 L Uncharacterized conserved protein (DUF2075)
HACLHNLC_03821 1.6e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HACLHNLC_03822 1.9e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HACLHNLC_03823 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HACLHNLC_03824 4e-153 yerO K Transcriptional regulator
HACLHNLC_03825 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HACLHNLC_03826 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HACLHNLC_03827 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HACLHNLC_03828 3.7e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HACLHNLC_03829 1.5e-121 sapB S MgtC SapB transporter

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)