ORF_ID e_value Gene_name EC_number CAZy COGs Description
GPPMODKI_00001 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GPPMODKI_00002 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPPMODKI_00003 4.5e-29 yazB K transcriptional
GPPMODKI_00004 9.9e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPPMODKI_00005 7e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPPMODKI_00006 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPPMODKI_00007 3.2e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
GPPMODKI_00008 2.3e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
GPPMODKI_00009 1.2e-269 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPPMODKI_00010 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GPPMODKI_00011 1.3e-154 yacD 5.2.1.8 O peptidyl-prolyl isomerase
GPPMODKI_00012 7.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPPMODKI_00013 1.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GPPMODKI_00014 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPPMODKI_00015 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GPPMODKI_00016 2.5e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GPPMODKI_00017 1.1e-184 KLT serine threonine protein kinase
GPPMODKI_00018 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
GPPMODKI_00019 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
GPPMODKI_00022 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
GPPMODKI_00023 2.3e-52 divIC D Septum formation initiator
GPPMODKI_00024 4.2e-102 yabQ S spore cortex biosynthesis protein
GPPMODKI_00025 1.9e-49 yabP S Sporulation protein YabP
GPPMODKI_00026 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GPPMODKI_00027 1.7e-276 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
GPPMODKI_00028 2.4e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPPMODKI_00029 6.2e-91 spoVT K stage V sporulation protein
GPPMODKI_00030 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPPMODKI_00031 3.7e-40 yabK S Peptide ABC transporter permease
GPPMODKI_00032 1.2e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GPPMODKI_00033 1.7e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPPMODKI_00034 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPPMODKI_00035 3.9e-246 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPPMODKI_00036 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
GPPMODKI_00037 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
GPPMODKI_00038 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
GPPMODKI_00039 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPPMODKI_00040 2.9e-27 sspF S DNA topological change
GPPMODKI_00041 7.8e-39 veg S protein conserved in bacteria
GPPMODKI_00042 1.4e-145 yabG S peptidase
GPPMODKI_00043 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GPPMODKI_00044 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GPPMODKI_00045 1.8e-232 rpfB GH23 T protein conserved in bacteria
GPPMODKI_00046 2.9e-142 tatD L hydrolase, TatD
GPPMODKI_00047 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPPMODKI_00048 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
GPPMODKI_00049 1.4e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPPMODKI_00050 4.7e-48 yazA L endonuclease containing a URI domain
GPPMODKI_00051 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
GPPMODKI_00052 7.7e-37 yabA L Involved in initiation control of chromosome replication
GPPMODKI_00053 8.8e-145 yaaT S stage 0 sporulation protein
GPPMODKI_00054 1.3e-182 holB 2.7.7.7 L DNA polymerase III
GPPMODKI_00055 1.2e-71 yaaR S protein conserved in bacteria
GPPMODKI_00056 7.5e-55 yaaQ S protein conserved in bacteria
GPPMODKI_00057 9.9e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPPMODKI_00058 6.2e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
GPPMODKI_00059 4.6e-189 yaaN P Belongs to the TelA family
GPPMODKI_00060 1.7e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
GPPMODKI_00061 2.2e-30 csfB S Inhibitor of sigma-G Gin
GPPMODKI_00062 6.7e-184 yaaC S YaaC-like Protein
GPPMODKI_00063 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GPPMODKI_00064 1.2e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GPPMODKI_00065 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GPPMODKI_00066 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GPPMODKI_00067 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPPMODKI_00068 2.6e-203 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GPPMODKI_00069 1.3e-09
GPPMODKI_00070 1.1e-121 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
GPPMODKI_00071 1.2e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
GPPMODKI_00072 1.7e-211 yaaH M Glycoside Hydrolase Family
GPPMODKI_00073 9.8e-100 yaaI Q COG1335 Amidases related to nicotinamidase
GPPMODKI_00074 3.5e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GPPMODKI_00075 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPPMODKI_00076 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPPMODKI_00077 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPPMODKI_00078 3.6e-32 yaaL S Protein of unknown function (DUF2508)
GPPMODKI_00079 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
GPPMODKI_00080 1.4e-14
GPPMODKI_00081 9.5e-67 S Domain of unknown function (DUF2479)
GPPMODKI_00082 4.7e-261 M Pectate lyase superfamily protein
GPPMODKI_00083 2.6e-104 mur1 NU Prophage endopeptidase tail
GPPMODKI_00084 1.8e-41 S Phage tail protein
GPPMODKI_00085 3.7e-235 D Phage tail tape measure protein
GPPMODKI_00086 5.2e-54 pi136 S Caudovirus prohead serine protease
GPPMODKI_00087 2.3e-144 S portal protein
GPPMODKI_00089 5.2e-216 terL S Terminase
GPPMODKI_00090 4.7e-45 terS L Terminase, small subunit
GPPMODKI_00093 2.9e-12
GPPMODKI_00094 3.4e-14 S HNH endonuclease
GPPMODKI_00102 5.8e-136 S COG0457 FOG TPR repeat
GPPMODKI_00103 8.8e-179 L Replication protein
GPPMODKI_00105 3.3e-08
GPPMODKI_00106 1.3e-26 traI 2.5.1.15 U relaxase mobilization nuclease domain protein
GPPMODKI_00111 2.8e-16 K Cro/C1-type HTH DNA-binding domain
GPPMODKI_00117 4.4e-124 yuaG 3.4.21.72 S protein conserved in bacteria
GPPMODKI_00118 9.7e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
GPPMODKI_00119 3.8e-260 M Pectate lyase superfamily protein
GPPMODKI_00130 1.7e-76 tspO T membrane
GPPMODKI_00131 1.7e-131 dksA T COG1734 DnaK suppressor protein
GPPMODKI_00132 6.1e-271 menF 5.4.4.2 HQ Isochorismate synthase
GPPMODKI_00133 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPPMODKI_00134 3.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
GPPMODKI_00135 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPPMODKI_00136 1e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GPPMODKI_00137 1e-212 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
GPPMODKI_00138 1.7e-121 troA P Belongs to the bacterial solute-binding protein 9 family
GPPMODKI_00139 4.3e-122 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GPPMODKI_00140 4.4e-159 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GPPMODKI_00141 1.4e-124 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
GPPMODKI_00142 2.3e-24 S Domain of Unknown Function (DUF1540)
GPPMODKI_00143 1.3e-185 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
GPPMODKI_00144 2.6e-239 cydA 1.10.3.14 C oxidase, subunit
GPPMODKI_00145 7.9e-41 rpmE2 J Ribosomal protein L31
GPPMODKI_00146 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
GPPMODKI_00147 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
GPPMODKI_00148 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GPPMODKI_00149 1.6e-76 ytkA S YtkA-like
GPPMODKI_00151 1.6e-76 dps P Belongs to the Dps family
GPPMODKI_00152 1.7e-61 ytkC S Bacteriophage holin family
GPPMODKI_00153 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
GPPMODKI_00154 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GPPMODKI_00155 3.2e-144 ytlC P ABC transporter
GPPMODKI_00156 4e-184 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
GPPMODKI_00157 7.4e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
GPPMODKI_00158 1.6e-38 ytmB S Protein of unknown function (DUF2584)
GPPMODKI_00159 6.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPPMODKI_00160 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPPMODKI_00161 0.0 asnB 6.3.5.4 E Asparagine synthase
GPPMODKI_00162 7.4e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
GPPMODKI_00163 1.9e-57 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPPMODKI_00164 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
GPPMODKI_00165 2.4e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
GPPMODKI_00166 4.7e-143 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
GPPMODKI_00168 1.9e-106 ytqB J Putative rRNA methylase
GPPMODKI_00169 1.4e-189 yhcC S Fe-S oxidoreductase
GPPMODKI_00170 9.7e-284 norB EGP COG0477 Permeases of the major facilitator superfamily
GPPMODKI_00171 1.6e-189 K helix_turn_helix, Arsenical Resistance Operon Repressor
GPPMODKI_00172 7.4e-40 ytzC S Protein of unknown function (DUF2524)
GPPMODKI_00173 8.6e-66 ytrA K GntR family transcriptional regulator
GPPMODKI_00174 1.9e-161 ytrB P abc transporter atp-binding protein
GPPMODKI_00175 1.2e-169 S ABC-2 family transporter protein
GPPMODKI_00176 9.1e-165 P ABC-2 family transporter protein
GPPMODKI_00177 1.8e-157
GPPMODKI_00178 2.9e-125 ytrE V ABC transporter, ATP-binding protein
GPPMODKI_00179 2e-220 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
GPPMODKI_00180 9.7e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPPMODKI_00181 3.9e-168 T PhoQ Sensor
GPPMODKI_00182 9.8e-135 bceA V ABC transporter, ATP-binding protein
GPPMODKI_00183 0.0 bceB V ABC transporter (permease)
GPPMODKI_00184 2.1e-126 ywaF S Integral membrane protein
GPPMODKI_00185 3e-207 yttB EGP Major facilitator Superfamily
GPPMODKI_00186 1.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
GPPMODKI_00187 1.2e-52 ytvB S Protein of unknown function (DUF4257)
GPPMODKI_00188 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPPMODKI_00189 1.3e-51 ytwF P Sulfurtransferase
GPPMODKI_00190 1.7e-84 M Acetyltransferase (GNAT) domain
GPPMODKI_00191 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
GPPMODKI_00192 1.2e-141 amyC P ABC transporter (permease)
GPPMODKI_00193 8.2e-168 amyD G Binding-protein-dependent transport system inner membrane component
GPPMODKI_00194 1.8e-245 msmE G Bacterial extracellular solute-binding protein
GPPMODKI_00195 9.8e-186 msmR K Transcriptional regulator
GPPMODKI_00196 9e-26 yteV S Sporulation protein Cse60
GPPMODKI_00197 5.8e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
GPPMODKI_00198 1.8e-234 ytfP S HI0933-like protein
GPPMODKI_00199 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPPMODKI_00200 8.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GPPMODKI_00201 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
GPPMODKI_00202 1.1e-127 ythP V ABC transporter
GPPMODKI_00203 7.1e-217 ythQ U Bacterial ABC transporter protein EcsB
GPPMODKI_00204 5.3e-229 pbuO S permease
GPPMODKI_00205 1.9e-269 pepV 3.5.1.18 E Dipeptidase
GPPMODKI_00206 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GPPMODKI_00207 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GPPMODKI_00208 2.2e-168 ytlQ
GPPMODKI_00209 1.2e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
GPPMODKI_00210 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
GPPMODKI_00211 3.5e-45 ytzH S YtzH-like protein
GPPMODKI_00212 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GPPMODKI_00213 5.1e-164 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
GPPMODKI_00214 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
GPPMODKI_00215 1.7e-51 ytzB S small secreted protein
GPPMODKI_00216 6.4e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
GPPMODKI_00217 1.7e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
GPPMODKI_00218 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GPPMODKI_00219 3.7e-148 ytpQ S Belongs to the UPF0354 family
GPPMODKI_00220 7e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPPMODKI_00221 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
GPPMODKI_00222 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GPPMODKI_00223 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GPPMODKI_00224 1.7e-16 ytxH S COG4980 Gas vesicle protein
GPPMODKI_00225 1.7e-43 ytxJ O Protein of unknown function (DUF2847)
GPPMODKI_00226 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
GPPMODKI_00227 6.4e-182 ccpA K catabolite control protein A
GPPMODKI_00228 5.1e-145 motA N flagellar motor
GPPMODKI_00229 3.7e-120 motS N Flagellar motor protein
GPPMODKI_00230 5.6e-230 acuC BQ histone deacetylase
GPPMODKI_00231 2.7e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
GPPMODKI_00232 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
GPPMODKI_00233 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GPPMODKI_00234 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPPMODKI_00235 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
GPPMODKI_00236 6.8e-125 azlC E AzlC protein
GPPMODKI_00237 4.4e-149 K Transcriptional regulator
GPPMODKI_00238 2.5e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPPMODKI_00239 1.5e-138 E GDSL-like Lipase/Acylhydrolase family
GPPMODKI_00241 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
GPPMODKI_00242 7.3e-09
GPPMODKI_00243 2.6e-222 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPPMODKI_00244 1.1e-32
GPPMODKI_00249 1.7e-07 S aspartate phosphatase
GPPMODKI_00250 5e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
GPPMODKI_00251 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPPMODKI_00252 2e-279 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
GPPMODKI_00253 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
GPPMODKI_00254 7.7e-109 yttP K Transcriptional regulator
GPPMODKI_00255 7.8e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
GPPMODKI_00256 2.3e-261 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GPPMODKI_00257 3.1e-240 braB E Component of the transport system for branched-chain amino acids
GPPMODKI_00258 4.1e-209 iscS2 2.8.1.7 E Cysteine desulfurase
GPPMODKI_00259 3.9e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPPMODKI_00260 3.9e-31 sspB S spore protein
GPPMODKI_00261 1.1e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GPPMODKI_00262 9.7e-310 ytcJ S amidohydrolase
GPPMODKI_00263 5.7e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPPMODKI_00264 6.4e-182 sppA OU signal peptide peptidase SppA
GPPMODKI_00265 4.5e-88 yteJ S RDD family
GPPMODKI_00266 5e-101 ytfI S Protein of unknown function (DUF2953)
GPPMODKI_00267 1.6e-60 ytfJ S Sporulation protein YtfJ
GPPMODKI_00268 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GPPMODKI_00269 9.7e-183 ytxK 2.1.1.72 L DNA methylase
GPPMODKI_00270 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPPMODKI_00271 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
GPPMODKI_00272 9.6e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GPPMODKI_00273 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
GPPMODKI_00275 1e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPPMODKI_00276 2.1e-128 ytkL S Belongs to the UPF0173 family
GPPMODKI_00277 2.8e-238 ytoI K transcriptional regulator containing CBS domains
GPPMODKI_00278 5.3e-47 ytpI S YtpI-like protein
GPPMODKI_00279 2.7e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
GPPMODKI_00280 5.8e-23
GPPMODKI_00281 5.1e-87 ytrI
GPPMODKI_00282 9.2e-56 ytrH S Sporulation protein YtrH
GPPMODKI_00283 0.0 dnaE 2.7.7.7 L DNA polymerase
GPPMODKI_00284 7.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
GPPMODKI_00285 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPPMODKI_00286 4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GPPMODKI_00287 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GPPMODKI_00288 2.2e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GPPMODKI_00289 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
GPPMODKI_00290 4.8e-194 ytvI S sporulation integral membrane protein YtvI
GPPMODKI_00291 1.1e-72 yeaL S membrane
GPPMODKI_00292 2.5e-47 yjdF S Protein of unknown function (DUF2992)
GPPMODKI_00293 3.7e-08 S Immunity protein 50
GPPMODKI_00294 9e-130 A Pre-toxin TG
GPPMODKI_00295 4.9e-106 S aspartate phosphatase
GPPMODKI_00297 2.8e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
GPPMODKI_00298 3.1e-242 icd 1.1.1.42 C isocitrate
GPPMODKI_00299 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
GPPMODKI_00300 3.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPPMODKI_00301 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
GPPMODKI_00302 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPPMODKI_00303 7.7e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GPPMODKI_00304 9.5e-107 ytaF P Probably functions as a manganese efflux pump
GPPMODKI_00305 9.9e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPPMODKI_00306 1.7e-159 ytbE S reductase
GPPMODKI_00307 1.3e-205 ytbD EGP Major facilitator Superfamily
GPPMODKI_00308 2e-67 ytcD K Transcriptional regulator
GPPMODKI_00309 1.5e-194 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GPPMODKI_00310 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GPPMODKI_00311 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPPMODKI_00312 4.5e-258 dnaB L Membrane attachment protein
GPPMODKI_00313 4.3e-172 dnaI L Primosomal protein DnaI
GPPMODKI_00314 9.3e-110 ytxB S SNARE associated Golgi protein
GPPMODKI_00315 1.6e-154 ytxC S YtxC-like family
GPPMODKI_00316 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPPMODKI_00317 7.1e-152 ysaA S HAD-hyrolase-like
GPPMODKI_00318 0.0 lytS 2.7.13.3 T Histidine kinase
GPPMODKI_00319 1.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
GPPMODKI_00320 3.1e-40 lrgA S effector of murein hydrolase LrgA
GPPMODKI_00321 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GPPMODKI_00322 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GPPMODKI_00323 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GPPMODKI_00324 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPPMODKI_00325 7.7e-42 ysdA S Membrane
GPPMODKI_00326 9.2e-68 ysdB S Sigma-w pathway protein YsdB
GPPMODKI_00327 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
GPPMODKI_00328 3.4e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
GPPMODKI_00329 4e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
GPPMODKI_00330 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
GPPMODKI_00331 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
GPPMODKI_00332 7.1e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
GPPMODKI_00333 9.8e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
GPPMODKI_00334 1.4e-250 araN G carbohydrate transport
GPPMODKI_00335 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
GPPMODKI_00336 9.9e-144 araQ G transport system permease
GPPMODKI_00337 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
GPPMODKI_00338 0.0 cstA T Carbon starvation protein
GPPMODKI_00339 3.4e-255 glcF C Glycolate oxidase
GPPMODKI_00340 1.8e-259 glcD 1.1.3.15 C FAD binding domain
GPPMODKI_00341 4.2e-203 ysfB KT regulator
GPPMODKI_00342 2e-32 sspI S Belongs to the SspI family
GPPMODKI_00343 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPPMODKI_00344 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPPMODKI_00345 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPPMODKI_00346 1.9e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPPMODKI_00347 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPPMODKI_00348 1.6e-83 cvpA S membrane protein, required for colicin V production
GPPMODKI_00349 0.0 polX L COG1796 DNA polymerase IV (family X)
GPPMODKI_00350 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GPPMODKI_00351 4.7e-67 yshE S membrane
GPPMODKI_00352 2.7e-123 ywbB S Protein of unknown function (DUF2711)
GPPMODKI_00353 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GPPMODKI_00354 9.2e-104 fadR K Transcriptional regulator
GPPMODKI_00355 2.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
GPPMODKI_00356 5.7e-138 etfB C Electron transfer flavoprotein
GPPMODKI_00357 1e-176 etfA C Electron transfer flavoprotein
GPPMODKI_00358 1.2e-298 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
GPPMODKI_00359 2.5e-52 trxA O Belongs to the thioredoxin family
GPPMODKI_00360 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GPPMODKI_00361 9.2e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
GPPMODKI_00362 1.2e-79 yslB S Protein of unknown function (DUF2507)
GPPMODKI_00363 1.4e-107 sdhC C succinate dehydrogenase
GPPMODKI_00364 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
GPPMODKI_00365 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
GPPMODKI_00366 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
GPPMODKI_00367 2e-30 gerE K Transcriptional regulator
GPPMODKI_00368 4.8e-73 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
GPPMODKI_00369 7.8e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GPPMODKI_00370 8.1e-199 gerM S COG5401 Spore germination protein
GPPMODKI_00371 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPPMODKI_00372 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPPMODKI_00373 4.2e-89 ysnB S Phosphoesterase
GPPMODKI_00376 1.9e-54 L Phage integrase family
GPPMODKI_00378 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
GPPMODKI_00379 3.5e-250 hsdM 2.1.1.72 L type I restriction-modification system
GPPMODKI_00380 3e-92 hsdS 3.1.21.3 V PFAM restriction modification system DNA specificity domain
GPPMODKI_00381 3.8e-12 pinR3 L Resolvase, N terminal domain
GPPMODKI_00382 2.6e-41 pinR3 L Resolvase, N terminal domain
GPPMODKI_00385 0.0 ilvB 2.2.1.6 E Acetolactate synthase
GPPMODKI_00386 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
GPPMODKI_00387 1.2e-191 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPPMODKI_00388 1.8e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPPMODKI_00389 9.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GPPMODKI_00390 3.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPPMODKI_00391 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPPMODKI_00392 2.1e-188 ysoA H Tetratricopeptide repeat
GPPMODKI_00393 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GPPMODKI_00394 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPPMODKI_00395 6e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
GPPMODKI_00396 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPPMODKI_00397 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
GPPMODKI_00398 3.8e-87 ysxD
GPPMODKI_00399 4.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPPMODKI_00400 3.6e-146 hemX O cytochrome C
GPPMODKI_00401 9.3e-175 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
GPPMODKI_00402 1e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
GPPMODKI_00403 1e-184 hemB 4.2.1.24 H Belongs to the ALAD family
GPPMODKI_00404 1.8e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
GPPMODKI_00405 5.2e-222 spoVID M stage VI sporulation protein D
GPPMODKI_00406 3.3e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPPMODKI_00407 2.1e-25
GPPMODKI_00408 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GPPMODKI_00409 2.8e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GPPMODKI_00410 7.8e-132 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
GPPMODKI_00411 4.5e-135 spoIIB S Sporulation related domain
GPPMODKI_00412 2.4e-101 maf D septum formation protein Maf
GPPMODKI_00413 1.8e-127 radC E Belongs to the UPF0758 family
GPPMODKI_00414 4e-184 mreB D Rod shape-determining protein MreB
GPPMODKI_00415 1.2e-157 mreC M Involved in formation and maintenance of cell shape
GPPMODKI_00416 5.4e-84 mreD M shape-determining protein
GPPMODKI_00417 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GPPMODKI_00418 8e-143 minD D Belongs to the ParA family
GPPMODKI_00419 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
GPPMODKI_00420 1.2e-160 spoIVFB S Stage IV sporulation protein
GPPMODKI_00421 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
GPPMODKI_00422 3.2e-56 ysxB J ribosomal protein
GPPMODKI_00423 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GPPMODKI_00424 3.3e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
GPPMODKI_00425 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPPMODKI_00426 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
GPPMODKI_00427 7.7e-160 pheA 4.2.1.51 E Prephenate dehydratase
GPPMODKI_00428 5.7e-92 niaR S small molecule binding protein (contains 3H domain)
GPPMODKI_00429 4.3e-222 nifS 2.8.1.7 E Cysteine desulfurase
GPPMODKI_00430 3.8e-298 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
GPPMODKI_00431 1.5e-152 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
GPPMODKI_00432 5.5e-211 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPPMODKI_00433 5.8e-145 safA M spore coat assembly protein SafA
GPPMODKI_00434 1.4e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GPPMODKI_00436 3.7e-93 bofC S BofC C-terminal domain
GPPMODKI_00437 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GPPMODKI_00438 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GPPMODKI_00439 1.6e-20 yrzS S Protein of unknown function (DUF2905)
GPPMODKI_00440 2e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPPMODKI_00441 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GPPMODKI_00442 5.6e-37 yajC U Preprotein translocase subunit YajC
GPPMODKI_00443 2.4e-60 yrzE S Protein of unknown function (DUF3792)
GPPMODKI_00444 4.7e-109 yrbG S membrane
GPPMODKI_00445 1.2e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPPMODKI_00446 3.8e-50 yrzD S Post-transcriptional regulator
GPPMODKI_00447 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPPMODKI_00448 2.8e-85 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
GPPMODKI_00449 5.7e-47 yrvD S Lipopolysaccharide assembly protein A domain
GPPMODKI_00450 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
GPPMODKI_00451 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPPMODKI_00452 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPPMODKI_00453 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GPPMODKI_00454 1.5e-278 lytH 3.5.1.28 M COG3103 SH3 domain protein
GPPMODKI_00457 9.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
GPPMODKI_00458 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GPPMODKI_00459 1.4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
GPPMODKI_00460 2.8e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
GPPMODKI_00461 7.8e-64 cymR K Transcriptional regulator
GPPMODKI_00462 1.8e-212 iscS 2.8.1.7 E Cysteine desulfurase
GPPMODKI_00463 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GPPMODKI_00464 1.7e-18 S COG0457 FOG TPR repeat
GPPMODKI_00465 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GPPMODKI_00466 1.5e-82 yrrD S protein conserved in bacteria
GPPMODKI_00467 2.9e-30 yrzR
GPPMODKI_00468 2.1e-08 S Protein of unknown function (DUF3918)
GPPMODKI_00469 4.4e-107 glnP P ABC transporter
GPPMODKI_00470 1.2e-109 gluC P ABC transporter
GPPMODKI_00471 7.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
GPPMODKI_00472 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GPPMODKI_00473 2.4e-163 yrrI S AI-2E family transporter
GPPMODKI_00474 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPPMODKI_00475 8.5e-41 yrzL S Belongs to the UPF0297 family
GPPMODKI_00476 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPPMODKI_00477 7.1e-46 yrzB S Belongs to the UPF0473 family
GPPMODKI_00478 1.7e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPPMODKI_00479 6.1e-117 yrrM 2.1.1.104 S O-methyltransferase
GPPMODKI_00480 1.7e-173 yegQ O Peptidase U32
GPPMODKI_00481 6.1e-246 yegQ O COG0826 Collagenase and related proteases
GPPMODKI_00482 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
GPPMODKI_00483 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GPPMODKI_00484 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
GPPMODKI_00485 3.1e-69 yrrS S Protein of unknown function (DUF1510)
GPPMODKI_00486 4.1e-27 yrzA S Protein of unknown function (DUF2536)
GPPMODKI_00487 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
GPPMODKI_00488 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPPMODKI_00489 3.6e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
GPPMODKI_00490 3.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GPPMODKI_00491 4.6e-35 yrhC S YrhC-like protein
GPPMODKI_00492 2.2e-79 yrhD S Protein of unknown function (DUF1641)
GPPMODKI_00493 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
GPPMODKI_00494 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
GPPMODKI_00495 8e-143 focA P Formate nitrite
GPPMODKI_00497 3.9e-93 yrhH Q methyltransferase
GPPMODKI_00498 9.1e-101 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
GPPMODKI_00499 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
GPPMODKI_00500 3.5e-211 ynfM EGP Major facilitator Superfamily
GPPMODKI_00501 2.9e-119 yybE K Transcriptional regulator
GPPMODKI_00502 1.2e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPPMODKI_00503 1e-181 romA S Beta-lactamase superfamily domain
GPPMODKI_00504 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
GPPMODKI_00505 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
GPPMODKI_00506 5.1e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
GPPMODKI_00507 1.6e-129 glvR K Helix-turn-helix domain, rpiR family
GPPMODKI_00508 2.1e-143 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
GPPMODKI_00509 2e-146 S hydrolase
GPPMODKI_00511 1.5e-91 yrdA S DinB family
GPPMODKI_00512 2.2e-80 yyaR K Acetyltransferase (GNAT) domain
GPPMODKI_00513 7.3e-221 tetL EGP Major facilitator Superfamily
GPPMODKI_00514 3.6e-29 yyaR K acetyltransferase
GPPMODKI_00515 2e-97 adk 2.7.4.3 F adenylate kinase activity
GPPMODKI_00516 5.6e-103 yrkN K Acetyltransferase (GNAT) family
GPPMODKI_00517 1.3e-221 yrkO P Protein of unknown function (DUF418)
GPPMODKI_00518 3.2e-124 T Transcriptional regulator
GPPMODKI_00519 2.1e-233 yrkQ T Histidine kinase
GPPMODKI_00520 3e-69 psiE S Belongs to the PsiE family
GPPMODKI_00521 1.2e-124 yecA E amino acid
GPPMODKI_00522 9.7e-105 K Transcriptional regulator
GPPMODKI_00523 8.1e-149 ydeE K AraC family transcriptional regulator
GPPMODKI_00524 2.7e-91 K Transcriptional regulator PadR-like family
GPPMODKI_00525 7.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
GPPMODKI_00526 9.8e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPPMODKI_00527 6.9e-218 EGP Major facilitator Superfamily
GPPMODKI_00528 1.6e-106 yqeD S SNARE associated Golgi protein
GPPMODKI_00529 2e-140 3.5.1.104 G Polysaccharide deacetylase
GPPMODKI_00530 1.1e-138 yqeF E GDSL-like Lipase/Acylhydrolase
GPPMODKI_00532 2e-94 yqeG S hydrolase of the HAD superfamily
GPPMODKI_00533 5.9e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GPPMODKI_00534 2.1e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPPMODKI_00535 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
GPPMODKI_00536 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPPMODKI_00537 4.8e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
GPPMODKI_00538 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GPPMODKI_00539 1.9e-138 yqeM Q Methyltransferase
GPPMODKI_00540 7.1e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPPMODKI_00541 2.8e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
GPPMODKI_00542 8e-105 comEB 3.5.4.12 F ComE operon protein 2
GPPMODKI_00543 0.0 comEC S Competence protein ComEC
GPPMODKI_00544 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
GPPMODKI_00545 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
GPPMODKI_00546 1.5e-203 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GPPMODKI_00547 1.4e-220 spoIIP M stage II sporulation protein P
GPPMODKI_00548 3.8e-54 yqxA S Protein of unknown function (DUF3679)
GPPMODKI_00549 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GPPMODKI_00550 2.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
GPPMODKI_00551 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GPPMODKI_00552 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPPMODKI_00553 0.0 dnaK O Heat shock 70 kDa protein
GPPMODKI_00554 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GPPMODKI_00555 7.8e-174 prmA J Methylates ribosomal protein L11
GPPMODKI_00556 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GPPMODKI_00557 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
GPPMODKI_00558 4.6e-158 yqeW P COG1283 Na phosphate symporter
GPPMODKI_00559 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GPPMODKI_00560 3.6e-68 yqeY S Yqey-like protein
GPPMODKI_00561 2.2e-230 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
GPPMODKI_00562 1.2e-119 yqfA S UPF0365 protein
GPPMODKI_00563 3.8e-54 yqfB
GPPMODKI_00564 9.3e-46 yqfC S sporulation protein YqfC
GPPMODKI_00565 2.6e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
GPPMODKI_00566 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
GPPMODKI_00567 0.0 yqfF S membrane-associated HD superfamily hydrolase
GPPMODKI_00568 1.7e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPPMODKI_00569 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GPPMODKI_00570 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GPPMODKI_00571 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPPMODKI_00572 1.8e-16 S YqzL-like protein
GPPMODKI_00573 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
GPPMODKI_00574 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GPPMODKI_00575 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GPPMODKI_00576 4.5e-112 ccpN K CBS domain
GPPMODKI_00577 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GPPMODKI_00578 6.1e-88 yaiI S Belongs to the UPF0178 family
GPPMODKI_00579 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GPPMODKI_00580 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GPPMODKI_00581 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
GPPMODKI_00582 5.4e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
GPPMODKI_00583 1.3e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPPMODKI_00584 1.9e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPPMODKI_00585 6.2e-51 yqfQ S YqfQ-like protein
GPPMODKI_00586 2.6e-239 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GPPMODKI_00587 1.3e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GPPMODKI_00588 1.6e-36 yqfT S Protein of unknown function (DUF2624)
GPPMODKI_00589 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
GPPMODKI_00590 2.9e-72 zur P Belongs to the Fur family
GPPMODKI_00591 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
GPPMODKI_00592 2.3e-52 yqfX S membrane
GPPMODKI_00593 4.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPPMODKI_00594 3.1e-47 yqfZ M LysM domain
GPPMODKI_00595 8.7e-131 yqgB S Protein of unknown function (DUF1189)
GPPMODKI_00596 4.4e-72 yqgC S protein conserved in bacteria
GPPMODKI_00597 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
GPPMODKI_00598 2e-228 yqgE EGP Major facilitator superfamily
GPPMODKI_00599 0.0 pbpA 3.4.16.4 M penicillin-binding protein
GPPMODKI_00600 1.7e-157 pstS P Phosphate
GPPMODKI_00601 5.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
GPPMODKI_00602 1.8e-156 pstA P Phosphate transport system permease
GPPMODKI_00603 6.6e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GPPMODKI_00604 1.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GPPMODKI_00605 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPPMODKI_00606 1.2e-50 yqzD
GPPMODKI_00607 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GPPMODKI_00608 1.6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPPMODKI_00609 4e-07 yqgO
GPPMODKI_00610 1.8e-213 nhaC C Na H antiporter
GPPMODKI_00611 1e-28 yqgQ S Protein conserved in bacteria
GPPMODKI_00612 4.9e-179 glcK 2.7.1.2 G Glucokinase
GPPMODKI_00613 1.1e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
GPPMODKI_00614 2e-199 yqgU
GPPMODKI_00615 6.9e-50 yqgV S Thiamine-binding protein
GPPMODKI_00616 5.4e-20 yqgW S Protein of unknown function (DUF2759)
GPPMODKI_00617 3.6e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
GPPMODKI_00618 3.1e-37 yqgY S Protein of unknown function (DUF2626)
GPPMODKI_00619 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
GPPMODKI_00621 3.8e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GPPMODKI_00622 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
GPPMODKI_00623 4.1e-186 corA P Mg2 transporter protein
GPPMODKI_00624 2.3e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPPMODKI_00625 5.4e-184 comGB NU COG1459 Type II secretory pathway, component PulF
GPPMODKI_00626 7.5e-49 comGC U Required for transformation and DNA binding
GPPMODKI_00627 2.6e-71 gspH NU Tfp pilus assembly protein FimT
GPPMODKI_00628 3.4e-20 comGE
GPPMODKI_00629 5.1e-66 comGF U Putative Competence protein ComGF
GPPMODKI_00630 2.5e-62 S ComG operon protein 7
GPPMODKI_00631 2.3e-26 yqzE S YqzE-like protein
GPPMODKI_00632 1.3e-54 yqzG S Protein of unknown function (DUF3889)
GPPMODKI_00633 7.2e-121 yqxM
GPPMODKI_00634 3.5e-71 sipW 3.4.21.89 U Signal peptidase
GPPMODKI_00635 3.3e-141 tasA S Cell division protein FtsN
GPPMODKI_00636 7.8e-55 sinR K transcriptional
GPPMODKI_00637 1.3e-21 sinI S Anti-repressor SinI
GPPMODKI_00638 9.3e-152 yqhG S Bacterial protein YqhG of unknown function
GPPMODKI_00639 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
GPPMODKI_00640 2.2e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
GPPMODKI_00641 7.9e-252 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPPMODKI_00642 9.8e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPPMODKI_00643 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
GPPMODKI_00644 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
GPPMODKI_00645 6.1e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
GPPMODKI_00646 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
GPPMODKI_00647 3.4e-62 yqhP
GPPMODKI_00648 1e-173 yqhQ S Protein of unknown function (DUF1385)
GPPMODKI_00649 3.7e-88 yqhR S Conserved membrane protein YqhR
GPPMODKI_00650 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
GPPMODKI_00651 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPPMODKI_00652 1.8e-36 yqhV S Protein of unknown function (DUF2619)
GPPMODKI_00653 4.2e-172 spoIIIAA S stage III sporulation protein AA
GPPMODKI_00654 1.7e-85 spoIIIAB S Stage III sporulation protein
GPPMODKI_00655 7.6e-29 spoIIIAC S stage III sporulation protein AC
GPPMODKI_00656 2.5e-41 spoIIIAD S Stage III sporulation protein AD
GPPMODKI_00657 3.1e-199 spoIIIAE S stage III sporulation protein AE
GPPMODKI_00658 2.6e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
GPPMODKI_00659 7.7e-118 spoIIIAG S stage III sporulation protein AG
GPPMODKI_00660 2.5e-62 spoIIIAH S SpoIIIAH-like protein
GPPMODKI_00661 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GPPMODKI_00662 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GPPMODKI_00663 8.1e-67 yqhY S protein conserved in bacteria
GPPMODKI_00664 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPPMODKI_00665 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPPMODKI_00666 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPPMODKI_00667 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPPMODKI_00668 1.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GPPMODKI_00669 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPPMODKI_00670 2.5e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
GPPMODKI_00671 3.9e-78 argR K Regulates arginine biosynthesis genes
GPPMODKI_00672 2.9e-299 recN L May be involved in recombinational repair of damaged DNA
GPPMODKI_00673 4.7e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
GPPMODKI_00674 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
GPPMODKI_00675 2.4e-187 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPPMODKI_00676 4.2e-13 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPPMODKI_00679 1.4e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
GPPMODKI_00681 1.8e-113 K Protein of unknown function (DUF1232)
GPPMODKI_00682 2e-101 ytaF P Probably functions as a manganese efflux pump
GPPMODKI_00683 2.5e-17
GPPMODKI_00684 1.4e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
GPPMODKI_00685 3.3e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GPPMODKI_00686 4.4e-214 mmgA 2.3.1.9 I Belongs to the thiolase family
GPPMODKI_00687 8.2e-154 hbdA 1.1.1.157 I Dehydrogenase
GPPMODKI_00688 1.8e-204 mmgC I acyl-CoA dehydrogenase
GPPMODKI_00689 1.3e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
GPPMODKI_00690 7.5e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
GPPMODKI_00691 1.6e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPPMODKI_00692 3.2e-34 yqzF S Protein of unknown function (DUF2627)
GPPMODKI_00693 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
GPPMODKI_00694 7.3e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
GPPMODKI_00695 2e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
GPPMODKI_00696 2e-208 buk 2.7.2.7 C Belongs to the acetokinase family
GPPMODKI_00697 1.8e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GPPMODKI_00698 8.6e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GPPMODKI_00699 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GPPMODKI_00700 1.4e-189 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPPMODKI_00701 1.6e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GPPMODKI_00702 1e-75 yqiW S Belongs to the UPF0403 family
GPPMODKI_00703 1.2e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
GPPMODKI_00704 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
GPPMODKI_00705 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GPPMODKI_00706 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
GPPMODKI_00707 3.1e-95 yqjB S protein conserved in bacteria
GPPMODKI_00709 1.2e-73 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
GPPMODKI_00710 4.1e-289 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GPPMODKI_00711 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
GPPMODKI_00712 6e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPPMODKI_00713 2.4e-25 yqzJ
GPPMODKI_00714 3.9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPPMODKI_00715 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPPMODKI_00716 2.5e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPPMODKI_00717 1.2e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GPPMODKI_00718 1.1e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GPPMODKI_00719 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
GPPMODKI_00720 1.4e-50 S GlpM protein
GPPMODKI_00721 2.4e-164 K LysR substrate binding domain
GPPMODKI_00722 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
GPPMODKI_00723 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GPPMODKI_00726 1.2e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GPPMODKI_00727 1.8e-128 IQ reductase
GPPMODKI_00728 0.0 pksJ Q Polyketide synthase of type I
GPPMODKI_00729 0.0 1.1.1.320 Q Polyketide synthase of type I
GPPMODKI_00730 0.0 Q Polyketide synthase of type I
GPPMODKI_00731 0.0 pksJ Q Polyketide synthase of type I
GPPMODKI_00732 0.0 pfaA Q Polyketide synthase of type I
GPPMODKI_00733 0.0 Q Polyketide synthase of type I
GPPMODKI_00734 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
GPPMODKI_00735 3.1e-220 eryK 1.14.13.154 C Cytochrome P450
GPPMODKI_00736 5.4e-239 pksG 2.3.3.10 I synthase
GPPMODKI_00737 4e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
GPPMODKI_00738 6.8e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPPMODKI_00739 1.4e-173 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
GPPMODKI_00740 6.1e-140 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
GPPMODKI_00741 2.9e-254 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
GPPMODKI_00742 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
GPPMODKI_00743 3.3e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPPMODKI_00745 1.3e-185 yueF S transporter activity
GPPMODKI_00747 1.2e-58 S YolD-like protein
GPPMODKI_00748 7.2e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPPMODKI_00749 8.7e-89 yqjY K acetyltransferase
GPPMODKI_00750 4.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
GPPMODKI_00751 3.3e-175 yqkA K GrpB protein
GPPMODKI_00752 3.8e-60 yqkB S Belongs to the HesB IscA family
GPPMODKI_00753 3.2e-39 yqkC S Protein of unknown function (DUF2552)
GPPMODKI_00754 2.8e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
GPPMODKI_00756 2.8e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
GPPMODKI_00758 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
GPPMODKI_00759 1.8e-220 yqxK 3.6.4.12 L DNA helicase
GPPMODKI_00760 3e-57 ansR K Transcriptional regulator
GPPMODKI_00761 8.5e-187 ansA 3.5.1.1 EJ L-asparaginase
GPPMODKI_00762 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
GPPMODKI_00763 2.7e-239 mleN C Na H antiporter
GPPMODKI_00764 7.7e-244 mleA 1.1.1.38 C malic enzyme
GPPMODKI_00765 5.7e-22
GPPMODKI_00766 1.7e-34 yqkK
GPPMODKI_00767 1.6e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
GPPMODKI_00768 1.9e-80 fur P Belongs to the Fur family
GPPMODKI_00769 3.7e-37 S Protein of unknown function (DUF4227)
GPPMODKI_00770 3.7e-165 xerD L recombinase XerD
GPPMODKI_00771 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPPMODKI_00772 4.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GPPMODKI_00773 4.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
GPPMODKI_00774 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
GPPMODKI_00775 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
GPPMODKI_00776 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPPMODKI_00777 4.8e-111 spoVAA S Stage V sporulation protein AA
GPPMODKI_00778 3.9e-60 spoVAB S Stage V sporulation protein AB
GPPMODKI_00779 1.3e-78 spoVAC S stage V sporulation protein AC
GPPMODKI_00780 1.4e-189 spoVAD I Stage V sporulation protein AD
GPPMODKI_00781 3.8e-57 spoVAEB S stage V sporulation protein
GPPMODKI_00782 5.2e-110 spoVAEA S stage V sporulation protein
GPPMODKI_00783 1.2e-269 spoVAF EG Stage V sporulation protein AF
GPPMODKI_00784 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GPPMODKI_00785 1.5e-153 ypuA S Secreted protein
GPPMODKI_00786 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPPMODKI_00787 2.4e-81 ccdC1 O Protein of unknown function (DUF1453)
GPPMODKI_00788 1.3e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
GPPMODKI_00789 6.4e-49 ypuD
GPPMODKI_00790 1.4e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPPMODKI_00791 1e-111 ribE 2.5.1.9 H Riboflavin synthase
GPPMODKI_00792 1.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPPMODKI_00793 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GPPMODKI_00794 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPPMODKI_00795 5.5e-92 ypuF S Domain of unknown function (DUF309)
GPPMODKI_00797 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GPPMODKI_00798 6.6e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GPPMODKI_00799 3.8e-93 ypuI S Protein of unknown function (DUF3907)
GPPMODKI_00800 1.1e-214 dacB 3.4.16.4 M Belongs to the peptidase S11 family
GPPMODKI_00801 2e-103 spmA S Spore maturation protein
GPPMODKI_00802 2.2e-88 spmB S Spore maturation protein
GPPMODKI_00803 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GPPMODKI_00804 1.6e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
GPPMODKI_00805 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
GPPMODKI_00806 2.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
GPPMODKI_00807 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPPMODKI_00808 0.0 resE 2.7.13.3 T Histidine kinase
GPPMODKI_00809 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
GPPMODKI_00810 4.8e-199 rsiX
GPPMODKI_00811 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPPMODKI_00812 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GPPMODKI_00813 3.6e-41 fer C Ferredoxin
GPPMODKI_00814 7e-195 ypbB 5.1.3.1 S protein conserved in bacteria
GPPMODKI_00815 1.5e-272 recQ 3.6.4.12 L DNA helicase
GPPMODKI_00816 9.9e-100 ypbD S metal-dependent membrane protease
GPPMODKI_00817 6.8e-75 ypbE M Lysin motif
GPPMODKI_00818 5.7e-85 ypbF S Protein of unknown function (DUF2663)
GPPMODKI_00819 4e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
GPPMODKI_00820 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GPPMODKI_00821 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
GPPMODKI_00822 4.5e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
GPPMODKI_00823 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
GPPMODKI_00824 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
GPPMODKI_00825 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
GPPMODKI_00826 1.5e-62 ypfA M Flagellar protein YcgR
GPPMODKI_00827 1.4e-12 S Family of unknown function (DUF5359)
GPPMODKI_00828 1e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GPPMODKI_00829 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
GPPMODKI_00830 2.5e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GPPMODKI_00831 4.7e-08 S YpzI-like protein
GPPMODKI_00832 1.1e-104 yphA
GPPMODKI_00833 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GPPMODKI_00834 1.9e-189 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GPPMODKI_00835 3.3e-16 yphE S Protein of unknown function (DUF2768)
GPPMODKI_00836 6.2e-134 yphF
GPPMODKI_00837 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GPPMODKI_00838 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPPMODKI_00839 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
GPPMODKI_00840 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
GPPMODKI_00841 6.9e-136 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
GPPMODKI_00842 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GPPMODKI_00843 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GPPMODKI_00844 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GPPMODKI_00845 1.1e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
GPPMODKI_00846 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPPMODKI_00847 1.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPPMODKI_00848 4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
GPPMODKI_00849 2.8e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPPMODKI_00850 1.2e-159 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPPMODKI_00851 3.9e-131 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
GPPMODKI_00852 6.8e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
GPPMODKI_00853 4.9e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GPPMODKI_00854 7.2e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GPPMODKI_00855 7.8e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPPMODKI_00856 2.9e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
GPPMODKI_00857 8.4e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GPPMODKI_00858 4.5e-233 S COG0457 FOG TPR repeat
GPPMODKI_00859 2.1e-99 ypiB S Belongs to the UPF0302 family
GPPMODKI_00860 4.7e-76 ypiF S Protein of unknown function (DUF2487)
GPPMODKI_00861 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
GPPMODKI_00862 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
GPPMODKI_00863 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
GPPMODKI_00864 2.1e-103 ypjA S membrane
GPPMODKI_00865 7.3e-141 ypjB S sporulation protein
GPPMODKI_00866 5e-226 oxdC 4.1.1.2 G Oxalate decarboxylase
GPPMODKI_00867 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
GPPMODKI_00868 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
GPPMODKI_00869 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GPPMODKI_00870 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
GPPMODKI_00871 5.6e-132 bshB1 S proteins, LmbE homologs
GPPMODKI_00872 1.8e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
GPPMODKI_00873 3.2e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GPPMODKI_00874 1.5e-180 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GPPMODKI_00875 7e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
GPPMODKI_00876 1.9e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPPMODKI_00877 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GPPMODKI_00878 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GPPMODKI_00879 6.7e-23 ypmA S Protein of unknown function (DUF4264)
GPPMODKI_00880 9e-81 ypmB S protein conserved in bacteria
GPPMODKI_00881 2.2e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
GPPMODKI_00882 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
GPPMODKI_00883 3e-130 dnaD L DNA replication protein DnaD
GPPMODKI_00884 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPPMODKI_00885 2.5e-91 ypoC
GPPMODKI_00886 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GPPMODKI_00887 4.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GPPMODKI_00888 2.4e-186 yppC S Protein of unknown function (DUF2515)
GPPMODKI_00891 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
GPPMODKI_00893 4.5e-45 yppG S YppG-like protein
GPPMODKI_00894 1.7e-72 hspX O Belongs to the small heat shock protein (HSP20) family
GPPMODKI_00895 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
GPPMODKI_00896 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
GPPMODKI_00897 2.5e-236 yprB L RNase_H superfamily
GPPMODKI_00898 9.9e-33 cotD S Inner spore coat protein D
GPPMODKI_00899 2.4e-98 ypsA S Belongs to the UPF0398 family
GPPMODKI_00900 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GPPMODKI_00901 1.1e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GPPMODKI_00902 6.6e-22 S YpzG-like protein
GPPMODKI_00904 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
GPPMODKI_00905 1.5e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPPMODKI_00906 2e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GPPMODKI_00907 1.9e-234 pbuX F xanthine
GPPMODKI_00908 1.2e-137 L Belongs to the 'phage' integrase family
GPPMODKI_00909 2.7e-16 K Helix-turn-helix XRE-family like proteins
GPPMODKI_00910 3.8e-32
GPPMODKI_00911 5e-43 S Phage regulatory protein Rha (Phage_pRha)
GPPMODKI_00912 5.8e-87
GPPMODKI_00916 2.1e-99
GPPMODKI_00917 3.9e-61 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
GPPMODKI_00919 1.8e-77 3.1.3.16 L DnaD domain protein
GPPMODKI_00920 1.7e-118 xkdC L IstB-like ATP binding protein
GPPMODKI_00922 8.5e-59 rusA L Endodeoxyribonuclease RusA
GPPMODKI_00924 3.4e-21 yqaO S Phage-like element PBSX protein XtrA
GPPMODKI_00926 1e-91
GPPMODKI_00927 4.2e-161 K Pfam:DUF955
GPPMODKI_00928 5.4e-68 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GPPMODKI_00930 5.1e-12 K Transcriptional regulator
GPPMODKI_00931 3.9e-88
GPPMODKI_00935 8.4e-77 L phage terminase small subunit
GPPMODKI_00936 1.2e-300 S Terminase
GPPMODKI_00937 8.5e-171 S Phage portal protein
GPPMODKI_00938 1.1e-83 S peptidase activity
GPPMODKI_00939 1.4e-152 gp36 S capsid protein
GPPMODKI_00940 2.5e-23
GPPMODKI_00941 1.5e-38 S Phage gp6-like head-tail connector protein
GPPMODKI_00942 2.9e-40 S Phage head-tail joining protein
GPPMODKI_00943 7e-47 S Bacteriophage HK97-gp10, putative tail-component
GPPMODKI_00945 1.7e-81 S Phage tail tube protein
GPPMODKI_00947 0.0 D phage tail tape measure protein
GPPMODKI_00948 6.5e-103 S Phage tail protein
GPPMODKI_00949 2.2e-227 NU Prophage endopeptidase tail
GPPMODKI_00950 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
GPPMODKI_00951 7.2e-99
GPPMODKI_00952 1.4e-09
GPPMODKI_00954 1.2e-57 S Pfam:Phage_holin_4_1
GPPMODKI_00955 1.1e-71 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GPPMODKI_00958 4.9e-85 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
GPPMODKI_00959 1.3e-23
GPPMODKI_00960 2.7e-27 K Helix-turn-helix domain
GPPMODKI_00961 8.5e-99 yrdC 3.5.1.19 Q Isochorismatase family
GPPMODKI_00963 6.4e-48 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
GPPMODKI_00964 5e-105 J Acetyltransferase (GNAT) domain
GPPMODKI_00965 3.5e-205 bcsA Q Naringenin-chalcone synthase
GPPMODKI_00966 1e-87 ypbQ S protein conserved in bacteria
GPPMODKI_00967 0.0 ypbR S Dynamin family
GPPMODKI_00968 3.5e-39 ypbS S Protein of unknown function (DUF2533)
GPPMODKI_00970 2.4e-164 polA 2.7.7.7 L 5'3' exonuclease
GPPMODKI_00972 3.2e-68 rnhA 3.1.26.4 L Ribonuclease
GPPMODKI_00973 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPPMODKI_00974 2.4e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
GPPMODKI_00975 1.5e-28 ypeQ S Zinc-finger
GPPMODKI_00976 6.1e-36 S Protein of unknown function (DUF2564)
GPPMODKI_00977 3.3e-12 degR
GPPMODKI_00978 1e-30 cspD K Cold-shock protein
GPPMODKI_00979 1.5e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
GPPMODKI_00980 2.5e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GPPMODKI_00981 3.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
GPPMODKI_00982 4.5e-98 ypgQ S phosphohydrolase
GPPMODKI_00983 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
GPPMODKI_00984 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GPPMODKI_00985 1e-75 yphP S Belongs to the UPF0403 family
GPPMODKI_00986 5.7e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
GPPMODKI_00987 2.7e-114 ypjP S YpjP-like protein
GPPMODKI_00988 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPPMODKI_00989 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPPMODKI_00990 1.4e-115 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GPPMODKI_00991 9.3e-110 hlyIII S protein, Hemolysin III
GPPMODKI_00992 6.1e-177 pspF K Transcriptional regulator
GPPMODKI_00993 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GPPMODKI_00994 2.6e-39 ypmP S Protein of unknown function (DUF2535)
GPPMODKI_00995 8.7e-107 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
GPPMODKI_00996 4e-136 ypmR E GDSL-like Lipase/Acylhydrolase
GPPMODKI_00997 1.6e-97 ypmS S protein conserved in bacteria
GPPMODKI_00998 4e-66 ypoP K transcriptional
GPPMODKI_00999 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPPMODKI_01000 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GPPMODKI_01001 5.3e-123 4.2.1.115 GM Polysaccharide biosynthesis protein
GPPMODKI_01002 9.8e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
GPPMODKI_01003 9.7e-180 cgeB S Spore maturation protein
GPPMODKI_01004 1.6e-52 cgeA
GPPMODKI_01005 1.1e-41 cgeC
GPPMODKI_01006 1.7e-248 cgeD M maturation of the outermost layer of the spore
GPPMODKI_01007 8.3e-145 yiiD K acetyltransferase
GPPMODKI_01009 5.4e-64 yosT L Bacterial transcription activator, effector binding domain
GPPMODKI_01010 1.1e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPPMODKI_01011 4.9e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GPPMODKI_01012 1.8e-122 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GPPMODKI_01013 6.7e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
GPPMODKI_01014 1.8e-156 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
GPPMODKI_01015 2.3e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
GPPMODKI_01016 8.3e-47 yokU S YokU-like protein, putative antitoxin
GPPMODKI_01017 9.1e-36 yozE S Belongs to the UPF0346 family
GPPMODKI_01018 4.9e-125 yodN
GPPMODKI_01020 6.2e-24 yozD S YozD-like protein
GPPMODKI_01021 2.3e-102 yodM 3.6.1.27 I Acid phosphatase homologues
GPPMODKI_01022 3.3e-55 yodL S YodL-like
GPPMODKI_01024 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
GPPMODKI_01025 6.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
GPPMODKI_01026 1.1e-34 yodI
GPPMODKI_01027 6.3e-128 yodH Q Methyltransferase
GPPMODKI_01028 1.2e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
GPPMODKI_01029 5.2e-133 yydK K Transcriptional regulator
GPPMODKI_01030 3e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GPPMODKI_01031 7.5e-280 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
GPPMODKI_01032 7.8e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPPMODKI_01033 1.4e-19 S Protein of unknown function (DUF3311)
GPPMODKI_01034 6.5e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
GPPMODKI_01035 3.9e-110 mhqD S Carboxylesterase
GPPMODKI_01036 4.5e-106 yodC C nitroreductase
GPPMODKI_01037 3e-56 yodB K transcriptional
GPPMODKI_01038 1.4e-70 yoaQ S Evidence 4 Homologs of previously reported genes of
GPPMODKI_01039 1.6e-67 yodA S tautomerase
GPPMODKI_01041 3.3e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
GPPMODKI_01042 9.2e-164 rarD S -transporter
GPPMODKI_01043 4.9e-23
GPPMODKI_01044 9.7e-61 yojF S Protein of unknown function (DUF1806)
GPPMODKI_01045 2.5e-126 yojG S deacetylase
GPPMODKI_01046 1.2e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GPPMODKI_01047 1.3e-241 norM V Multidrug efflux pump
GPPMODKI_01049 2.4e-110 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPPMODKI_01050 1.4e-223 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
GPPMODKI_01051 5.2e-226 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
GPPMODKI_01052 1.9e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GPPMODKI_01053 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
GPPMODKI_01054 0.0 yojO P Von Willebrand factor
GPPMODKI_01055 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
GPPMODKI_01056 2.4e-178 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
GPPMODKI_01057 5.3e-141 S Metallo-beta-lactamase superfamily
GPPMODKI_01058 4.6e-161 yocS S -transporter
GPPMODKI_01059 5.1e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GPPMODKI_01060 3.2e-166 sodA 1.15.1.1 P Superoxide dismutase
GPPMODKI_01061 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
GPPMODKI_01062 2.9e-287 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
GPPMODKI_01063 1.6e-31 yozC
GPPMODKI_01065 2.4e-56 yozO S Bacterial PH domain
GPPMODKI_01066 8.5e-37 yocN
GPPMODKI_01067 1.4e-43 yozN
GPPMODKI_01068 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
GPPMODKI_01069 1.7e-08
GPPMODKI_01070 7.8e-10 yocL
GPPMODKI_01071 9.5e-54 dksA T general stress protein
GPPMODKI_01073 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPPMODKI_01074 0.0 recQ 3.6.4.12 L DNA helicase
GPPMODKI_01075 1.7e-114 yocH CBM50 M COG1388 FOG LysM repeat
GPPMODKI_01077 4.6e-105 yocD 3.4.17.13 V peptidase S66
GPPMODKI_01078 5.7e-68 yocD 3.4.17.13 V peptidase S66
GPPMODKI_01079 1.9e-94 yocC
GPPMODKI_01080 1.1e-139 yocB J Protein required for attachment to host cells
GPPMODKI_01081 6.9e-90 yozB S membrane
GPPMODKI_01082 3.9e-119 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GPPMODKI_01083 1.7e-54 czrA K transcriptional
GPPMODKI_01084 1.9e-92 yobW
GPPMODKI_01085 6.5e-136 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
GPPMODKI_01086 1.7e-94 yobS K Transcriptional regulator
GPPMODKI_01087 3e-133 yobQ K helix_turn_helix, arabinose operon control protein
GPPMODKI_01088 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
GPPMODKI_01089 3.9e-299 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
GPPMODKI_01090 2.6e-77 S SMI1-KNR4 cell-wall
GPPMODKI_01091 1.3e-44
GPPMODKI_01092 1.9e-98 hpr K helix_turn_helix multiple antibiotic resistance protein
GPPMODKI_01094 6.3e-26 yoaF
GPPMODKI_01095 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GPPMODKI_01096 2.1e-193 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPPMODKI_01097 8.8e-273 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
GPPMODKI_01098 1.9e-204 yoaB EGP Major facilitator Superfamily
GPPMODKI_01099 1.4e-136 yoxB
GPPMODKI_01100 5.2e-42 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GPPMODKI_01101 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GPPMODKI_01102 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
GPPMODKI_01103 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPPMODKI_01104 2.8e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPPMODKI_01105 2.2e-149 gltC K Transcriptional regulator
GPPMODKI_01106 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
GPPMODKI_01107 5e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
GPPMODKI_01108 2.9e-23 1.16.3.1 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GPPMODKI_01109 2.2e-17 1.16.3.1 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GPPMODKI_01110 4.2e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
GPPMODKI_01111 1.5e-155 gltR1 K Transcriptional regulator
GPPMODKI_01112 4.8e-15 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPPMODKI_01113 1.8e-50 ybzH K Helix-turn-helix domain
GPPMODKI_01114 3e-199 ybcL EGP Major facilitator Superfamily
GPPMODKI_01115 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
GPPMODKI_01116 1.8e-34 yoeD G Helix-turn-helix domain
GPPMODKI_01117 3.5e-97 L Integrase
GPPMODKI_01119 3.4e-97 yoeB S IseA DL-endopeptidase inhibitor
GPPMODKI_01120 7.9e-247 yoeA V MATE efflux family protein
GPPMODKI_01121 1.5e-188 yoxA 5.1.3.3 G Aldose 1-epimerase
GPPMODKI_01122 3.7e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
GPPMODKI_01123 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPPMODKI_01124 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPPMODKI_01125 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPPMODKI_01126 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPPMODKI_01127 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
GPPMODKI_01128 7.1e-65 yngL S Protein of unknown function (DUF1360)
GPPMODKI_01129 7.8e-304 yngK T Glycosyl hydrolase-like 10
GPPMODKI_01130 7e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
GPPMODKI_01131 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GPPMODKI_01132 8.7e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
GPPMODKI_01133 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
GPPMODKI_01134 2.8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
GPPMODKI_01135 1.5e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
GPPMODKI_01136 1.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GPPMODKI_01137 3.2e-104 yngC S SNARE associated Golgi protein
GPPMODKI_01138 8.6e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GPPMODKI_01139 1.9e-71 yngA S membrane
GPPMODKI_01140 6.3e-145 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
GPPMODKI_01141 2.1e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
GPPMODKI_01142 1.2e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GPPMODKI_01143 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GPPMODKI_01144 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPPMODKI_01145 1.1e-220 bioI 1.14.14.46 C Cytochrome P450
GPPMODKI_01146 5e-252 yxjC EG COG2610 H gluconate symporter and related permeases
GPPMODKI_01147 2.9e-125 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GPPMODKI_01148 7.8e-120 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GPPMODKI_01149 6.9e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
GPPMODKI_01150 1.3e-218 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GPPMODKI_01151 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPPMODKI_01152 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPPMODKI_01153 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPPMODKI_01154 3.6e-285 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
GPPMODKI_01155 1.4e-250 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
GPPMODKI_01156 4.9e-128 T Transcriptional regulatory protein, C terminal
GPPMODKI_01157 3.1e-235 T PhoQ Sensor
GPPMODKI_01158 1.3e-51 S Domain of unknown function (DUF4870)
GPPMODKI_01159 1.3e-287 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
GPPMODKI_01160 3e-212 S Platelet-activating factor acetylhydrolase, isoform II
GPPMODKI_01162 9.1e-303 yndJ S YndJ-like protein
GPPMODKI_01163 4.9e-76 yndH S Domain of unknown function (DUF4166)
GPPMODKI_01164 7.1e-155 yndG S DoxX-like family
GPPMODKI_01165 5e-224 exuT G Sugar (and other) transporter
GPPMODKI_01166 4.1e-181 kdgR_1 K transcriptional
GPPMODKI_01167 7.8e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPPMODKI_01168 9.8e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
GPPMODKI_01169 2.6e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
GPPMODKI_01170 5.1e-78 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
GPPMODKI_01171 1.6e-97 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
GPPMODKI_01172 2.3e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
GPPMODKI_01173 1.6e-250 agcS E Sodium alanine symporter
GPPMODKI_01174 5.1e-41 ynfC
GPPMODKI_01175 6e-13
GPPMODKI_01176 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPPMODKI_01177 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPPMODKI_01178 1.5e-68 yccU S CoA-binding protein
GPPMODKI_01179 1.4e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GPPMODKI_01180 1.3e-50 yneR S Belongs to the HesB IscA family
GPPMODKI_01181 4.4e-54 yneQ
GPPMODKI_01182 8.3e-75 yneP S Thioesterase-like superfamily
GPPMODKI_01183 4.6e-33 tlp S Belongs to the Tlp family
GPPMODKI_01185 1.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPPMODKI_01186 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GPPMODKI_01187 7.5e-15 sspO S Belongs to the SspO family
GPPMODKI_01188 2.3e-19 sspP S Belongs to the SspP family
GPPMODKI_01189 3.2e-62 hspX O Spore coat protein
GPPMODKI_01190 1.9e-74 yneK S Protein of unknown function (DUF2621)
GPPMODKI_01191 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
GPPMODKI_01192 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
GPPMODKI_01193 1.7e-125 ccdA O cytochrome c biogenesis protein
GPPMODKI_01194 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
GPPMODKI_01195 2.3e-28 yneF S UPF0154 protein
GPPMODKI_01196 3.7e-81 yneE S Sporulation inhibitor of replication protein sirA
GPPMODKI_01197 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPPMODKI_01198 9.8e-33 ynzC S UPF0291 protein
GPPMODKI_01199 3.5e-112 yneB L resolvase
GPPMODKI_01200 1.4e-50 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
GPPMODKI_01201 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPPMODKI_01202 7.8e-12 yoaW
GPPMODKI_01203 3.2e-72 yndM S Protein of unknown function (DUF2512)
GPPMODKI_01204 8e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
GPPMODKI_01206 2.2e-143 yndL S Replication protein
GPPMODKI_01207 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
GPPMODKI_01208 0.0 yobO M Pectate lyase superfamily protein
GPPMODKI_01210 3.5e-94 yvgO
GPPMODKI_01211 5e-23 yvgO
GPPMODKI_01212 1.5e-65 2.3.1.128 J Acetyltransferase (GNAT) domain
GPPMODKI_01214 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
GPPMODKI_01215 8.6e-201 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPPMODKI_01216 1.1e-118 ynaE S Domain of unknown function (DUF3885)
GPPMODKI_01219 1.4e-33
GPPMODKI_01220 3.2e-24
GPPMODKI_01221 1.1e-43 S Acetyltransferase (GNAT) domain
GPPMODKI_01222 1.1e-93 yokK S SMI1 / KNR4 family
GPPMODKI_01223 2.4e-51 S SMI1-KNR4 cell-wall
GPPMODKI_01224 5.5e-293 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
GPPMODKI_01225 9.8e-143 yoaP 3.1.3.18 K YoaP-like
GPPMODKI_01227 1.9e-16
GPPMODKI_01228 1.2e-12 ccmM S Bacterial transferase hexapeptide (six repeats)
GPPMODKI_01229 1.6e-185 adhP 1.1.1.1 C alcohol dehydrogenase
GPPMODKI_01230 1.3e-66 S DinB family
GPPMODKI_01231 7.7e-68 K WYL domain
GPPMODKI_01232 9.6e-33 K WYL domain
GPPMODKI_01233 7e-17
GPPMODKI_01237 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
GPPMODKI_01238 1.6e-285 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
GPPMODKI_01239 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
GPPMODKI_01240 6.2e-213 xylR GK ROK family
GPPMODKI_01241 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
GPPMODKI_01242 2.8e-252 xynT G MFS/sugar transport protein
GPPMODKI_01243 6.7e-209 mrjp G Major royal jelly protein
GPPMODKI_01245 3.2e-21
GPPMODKI_01246 5.8e-22
GPPMODKI_01249 3.1e-31 S nuclease activity
GPPMODKI_01250 1.7e-30
GPPMODKI_01251 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
GPPMODKI_01252 1.6e-67 glnR K transcriptional
GPPMODKI_01253 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
GPPMODKI_01254 1.9e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPPMODKI_01255 1.3e-69 spoVK O stage V sporulation protein K
GPPMODKI_01256 4.3e-247 cisA2 L Recombinase
GPPMODKI_01258 2.6e-90 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GPPMODKI_01264 1.2e-28 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPPMODKI_01265 1.6e-149 S Thymidylate synthase
GPPMODKI_01266 1.6e-50 S Protein of unknown function (DUF1643)
GPPMODKI_01269 1.1e-71 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
GPPMODKI_01270 1.4e-31 O Glutaredoxin
GPPMODKI_01271 3.1e-13
GPPMODKI_01272 1.3e-59 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPPMODKI_01274 9.4e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPPMODKI_01276 2.9e-168 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPPMODKI_01277 1.4e-40 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPPMODKI_01278 4e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPPMODKI_01279 5.3e-55 S NrdI Flavodoxin like
GPPMODKI_01286 2.6e-12 larC 4.99.1.12 FJ Protein conserved in bacteria
GPPMODKI_01291 9.3e-19
GPPMODKI_01294 6.4e-09
GPPMODKI_01298 3.7e-79 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
GPPMODKI_01299 5.8e-16 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
GPPMODKI_01300 9.9e-86 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
GPPMODKI_01301 9.2e-71 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
GPPMODKI_01304 6.8e-24 S protein conserved in bacteria
GPPMODKI_01305 3.4e-292 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
GPPMODKI_01306 3.4e-173 S PD-(D/E)XK nuclease superfamily
GPPMODKI_01307 1.5e-146 3.6.4.12 L DNA primase activity
GPPMODKI_01308 9.9e-240 3.6.4.12 L DnaB-like helicase C terminal domain
GPPMODKI_01310 1.4e-158 S AAA domain
GPPMODKI_01311 1.4e-170
GPPMODKI_01312 1.2e-70 nrnB S phosphohydrolase (DHH superfamily)
GPPMODKI_01317 2.1e-220 M Parallel beta-helix repeats
GPPMODKI_01318 7.8e-93 S Pfam:DUF867
GPPMODKI_01320 7.4e-25 S YopX protein
GPPMODKI_01323 3.3e-126 yoqW S Belongs to the SOS response-associated peptidase family
GPPMODKI_01324 6.6e-137 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
GPPMODKI_01325 1.7e-08 xtmA L phage terminase small subunit
GPPMODKI_01326 4.6e-42
GPPMODKI_01330 4.1e-74
GPPMODKI_01334 2.2e-85 S Protein of unknown function (DUF1273)
GPPMODKI_01342 4.8e-09 S YopX protein
GPPMODKI_01343 8.1e-42
GPPMODKI_01347 2.8e-13 K Transcriptional regulator
GPPMODKI_01348 2.2e-33
GPPMODKI_01349 4.3e-189
GPPMODKI_01350 2e-37 L Belongs to the 'phage' integrase family
GPPMODKI_01356 2.1e-80
GPPMODKI_01357 4.1e-18
GPPMODKI_01363 7.7e-25
GPPMODKI_01370 4.6e-68 yoaW
GPPMODKI_01371 1.4e-20 I Acyltransferase family
GPPMODKI_01378 2.4e-199 3.1.21.3 L Domain of unknown function (DUF4942)
GPPMODKI_01380 1.7e-155
GPPMODKI_01383 1.3e-58 ftsZ D Tubulin/FtsZ family, GTPase domain
GPPMODKI_01387 0.0
GPPMODKI_01388 3.6e-34 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPPMODKI_01391 6.5e-221
GPPMODKI_01392 9.7e-39
GPPMODKI_01393 4.5e-18
GPPMODKI_01394 8.7e-110
GPPMODKI_01395 1.8e-18
GPPMODKI_01396 5.3e-39
GPPMODKI_01398 6.2e-69
GPPMODKI_01401 4.7e-56
GPPMODKI_01402 9.7e-86
GPPMODKI_01403 1.2e-97
GPPMODKI_01404 2.3e-57
GPPMODKI_01406 3.9e-49
GPPMODKI_01407 7.7e-74
GPPMODKI_01409 1.1e-57
GPPMODKI_01410 1.6e-49
GPPMODKI_01411 1.2e-172 xerH A Belongs to the 'phage' integrase family
GPPMODKI_01413 8.5e-40
GPPMODKI_01415 2.1e-53
GPPMODKI_01416 3.4e-39 S COG NOG14552 non supervised orthologous group
GPPMODKI_01417 5.6e-44 S Bacteriophage holin family
GPPMODKI_01420 1.6e-08
GPPMODKI_01423 9e-27 S Phage tail tube protein
GPPMODKI_01428 3.4e-22 S Phage gp6-like head-tail connector protein
GPPMODKI_01433 1.2e-37 K BRO family, N-terminal domain
GPPMODKI_01435 5.4e-55
GPPMODKI_01437 1.4e-53 L Recombinase
GPPMODKI_01438 3.8e-45 yuaG 3.4.21.72 S protein conserved in bacteria
GPPMODKI_01439 1.7e-80 yuaF OU Membrane protein implicated in regulation of membrane protease activity
GPPMODKI_01440 7.6e-80 yuaE S DinB superfamily
GPPMODKI_01441 6e-108 yuaD S MOSC domain
GPPMODKI_01442 1.6e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
GPPMODKI_01443 5.5e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
GPPMODKI_01444 1.5e-95 yuaC K Belongs to the GbsR family
GPPMODKI_01445 3.3e-92 yuaB
GPPMODKI_01446 5.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
GPPMODKI_01447 4.8e-146 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPPMODKI_01448 7.7e-219 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPPMODKI_01449 6.2e-122 G Cupin
GPPMODKI_01450 3.7e-51 yjcN
GPPMODKI_01452 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GPPMODKI_01453 4.9e-194 yubA S transporter activity
GPPMODKI_01454 6.1e-185 ygjR S Oxidoreductase
GPPMODKI_01455 2.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
GPPMODKI_01456 1.8e-236 mcpA NT chemotaxis protein
GPPMODKI_01457 1.3e-223 mcpA NT chemotaxis protein
GPPMODKI_01458 1.8e-236 mcpA NT chemotaxis protein
GPPMODKI_01459 8.1e-221 mcpA NT chemotaxis protein
GPPMODKI_01460 4.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
GPPMODKI_01461 1.8e-40
GPPMODKI_01462 1e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
GPPMODKI_01463 1.5e-76 yugU S Uncharacterised protein family UPF0047
GPPMODKI_01464 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
GPPMODKI_01465 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
GPPMODKI_01466 8.3e-117 yugP S Zn-dependent protease
GPPMODKI_01467 1e-17
GPPMODKI_01468 6.7e-27 mstX S Membrane-integrating protein Mistic
GPPMODKI_01469 1.6e-180 yugO P COG1226 Kef-type K transport systems
GPPMODKI_01470 2.4e-71 yugN S YugN-like family
GPPMODKI_01472 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
GPPMODKI_01473 5.7e-95 S NADPH-dependent FMN reductase
GPPMODKI_01474 1.4e-118 ycaC Q Isochorismatase family
GPPMODKI_01475 7.4e-230 yugK C Dehydrogenase
GPPMODKI_01476 1.6e-224 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
GPPMODKI_01477 1.8e-34 yuzA S Domain of unknown function (DUF378)
GPPMODKI_01478 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
GPPMODKI_01479 2.1e-208 yugH 2.6.1.1 E Aminotransferase
GPPMODKI_01480 2e-83 alaR K Transcriptional regulator
GPPMODKI_01481 1.4e-155 yugF I Hydrolase
GPPMODKI_01482 2.7e-39 yugE S Domain of unknown function (DUF1871)
GPPMODKI_01483 3.5e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GPPMODKI_01484 3.1e-229 T PhoQ Sensor
GPPMODKI_01485 6.9e-68 kapB G Kinase associated protein B
GPPMODKI_01486 4.5e-118 kapD L the KinA pathway to sporulation
GPPMODKI_01487 1.5e-185 yuxJ EGP Major facilitator Superfamily
GPPMODKI_01488 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
GPPMODKI_01489 3.8e-72 yuxK S protein conserved in bacteria
GPPMODKI_01490 9.3e-74 yufK S Family of unknown function (DUF5366)
GPPMODKI_01491 1.7e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
GPPMODKI_01492 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
GPPMODKI_01493 5.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
GPPMODKI_01494 5e-287 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
GPPMODKI_01495 1.1e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
GPPMODKI_01496 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
GPPMODKI_01497 1.8e-12
GPPMODKI_01498 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GPPMODKI_01499 9.2e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPPMODKI_01500 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPPMODKI_01501 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPPMODKI_01502 5e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPPMODKI_01503 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPPMODKI_01504 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
GPPMODKI_01505 6e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
GPPMODKI_01506 3.4e-112 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPPMODKI_01507 6.2e-257 comP 2.7.13.3 T Histidine kinase
GPPMODKI_01509 4.4e-62 comQ H Polyprenyl synthetase
GPPMODKI_01511 3.6e-52 yuzC
GPPMODKI_01512 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
GPPMODKI_01513 2.5e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPPMODKI_01514 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
GPPMODKI_01515 7.2e-68 yueI S Protein of unknown function (DUF1694)
GPPMODKI_01516 2.8e-38 yueH S YueH-like protein
GPPMODKI_01517 6.4e-34 yueG S Spore germination protein gerPA/gerPF
GPPMODKI_01518 5.6e-187 yueF S transporter activity
GPPMODKI_01519 2.1e-22 S Protein of unknown function (DUF2642)
GPPMODKI_01520 3.7e-96 yueE S phosphohydrolase
GPPMODKI_01521 1.9e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPPMODKI_01522 6.5e-76 yueC S Family of unknown function (DUF5383)
GPPMODKI_01523 0.0 esaA S type VII secretion protein EsaA
GPPMODKI_01524 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GPPMODKI_01525 3.7e-206 essB S WXG100 protein secretion system (Wss), protein YukC
GPPMODKI_01526 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
GPPMODKI_01527 3.3e-46 esxA S Belongs to the WXG100 family
GPPMODKI_01528 3.2e-228 yukF QT Transcriptional regulator
GPPMODKI_01529 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
GPPMODKI_01530 7.5e-134 yukJ S Uncharacterized conserved protein (DUF2278)
GPPMODKI_01531 1.3e-34 mbtH S MbtH-like protein
GPPMODKI_01532 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPPMODKI_01533 3.5e-174 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
GPPMODKI_01534 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
GPPMODKI_01535 3.6e-224 entC 5.4.4.2 HQ Isochorismate synthase
GPPMODKI_01536 7.1e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPPMODKI_01537 1.5e-166 besA S Putative esterase
GPPMODKI_01538 1.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
GPPMODKI_01539 1.1e-101 bioY S Biotin biosynthesis protein
GPPMODKI_01540 2e-207 yuiF S antiporter
GPPMODKI_01541 4.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPPMODKI_01542 1.6e-77 yuiD S protein conserved in bacteria
GPPMODKI_01543 1.4e-118 yuiC S protein conserved in bacteria
GPPMODKI_01544 9.9e-28 yuiB S Putative membrane protein
GPPMODKI_01545 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
GPPMODKI_01546 2.1e-185 yumC 1.18.1.2, 1.19.1.1 C reductase
GPPMODKI_01548 5.1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GPPMODKI_01549 4.8e-29
GPPMODKI_01550 2.6e-70 CP Membrane
GPPMODKI_01551 8.1e-123 V ABC transporter
GPPMODKI_01553 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
GPPMODKI_01555 1.6e-18 rimJ 2.3.1.128 J Alanine acetyltransferase
GPPMODKI_01556 3.6e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
GPPMODKI_01557 1.1e-62 erpA S Belongs to the HesB IscA family
GPPMODKI_01558 1.1e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPPMODKI_01559 5e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPPMODKI_01560 2.4e-39 yuzB S Belongs to the UPF0349 family
GPPMODKI_01561 3.2e-208 yutJ 1.6.99.3 C NADH dehydrogenase
GPPMODKI_01562 9.7e-55 yuzD S protein conserved in bacteria
GPPMODKI_01563 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
GPPMODKI_01564 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
GPPMODKI_01565 6.4e-168 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GPPMODKI_01566 1.1e-195 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPPMODKI_01567 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
GPPMODKI_01568 4.6e-196 yutH S Spore coat protein
GPPMODKI_01569 2.3e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
GPPMODKI_01570 1.4e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GPPMODKI_01571 7.3e-74 yutE S Protein of unknown function DUF86
GPPMODKI_01572 8.2e-47 yutD S protein conserved in bacteria
GPPMODKI_01573 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GPPMODKI_01574 1.1e-194 lytH M Peptidase, M23
GPPMODKI_01575 5.1e-131 yunB S Sporulation protein YunB (Spo_YunB)
GPPMODKI_01576 9e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
GPPMODKI_01577 1.8e-145 yunE S membrane transporter protein
GPPMODKI_01578 8.1e-170 yunF S Protein of unknown function DUF72
GPPMODKI_01579 5.2e-62 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
GPPMODKI_01580 2.4e-264 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
GPPMODKI_01581 8e-304 pucR QT COG2508 Regulator of polyketide synthase expression
GPPMODKI_01583 5.7e-179 S Aspartate phosphatase response regulator
GPPMODKI_01584 2.8e-69
GPPMODKI_01585 3.8e-213 blt EGP Major facilitator Superfamily
GPPMODKI_01586 2.3e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
GPPMODKI_01587 8.1e-235 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
GPPMODKI_01588 4.1e-169 bsn L Ribonuclease
GPPMODKI_01589 1.6e-205 msmX P Belongs to the ABC transporter superfamily
GPPMODKI_01590 1.4e-133 yurK K UTRA
GPPMODKI_01591 1.8e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
GPPMODKI_01592 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
GPPMODKI_01593 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
GPPMODKI_01594 8.9e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
GPPMODKI_01595 9.4e-186 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
GPPMODKI_01596 2.9e-165 K helix_turn_helix, mercury resistance
GPPMODKI_01597 4e-14
GPPMODKI_01598 3.4e-76
GPPMODKI_01599 2.1e-22 S Sporulation delaying protein SdpA
GPPMODKI_01601 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
GPPMODKI_01602 3.3e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
GPPMODKI_01603 1.1e-124 Q ubiE/COQ5 methyltransferase family
GPPMODKI_01604 1.1e-78 yncE S Protein of unknown function (DUF2691)
GPPMODKI_01605 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
GPPMODKI_01606 3e-270 sufB O FeS cluster assembly
GPPMODKI_01607 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
GPPMODKI_01608 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPPMODKI_01609 7e-245 sufD O assembly protein SufD
GPPMODKI_01610 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GPPMODKI_01611 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPPMODKI_01612 1.1e-144 metQ P Belongs to the NlpA lipoprotein family
GPPMODKI_01613 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
GPPMODKI_01614 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPPMODKI_01615 5e-57 yusD S SCP-2 sterol transfer family
GPPMODKI_01616 1.6e-54 yusE CO Thioredoxin
GPPMODKI_01617 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
GPPMODKI_01618 3.7e-40 yusG S Protein of unknown function (DUF2553)
GPPMODKI_01619 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
GPPMODKI_01620 8.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
GPPMODKI_01621 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
GPPMODKI_01622 4.7e-216 fadA 2.3.1.16 I Belongs to the thiolase family
GPPMODKI_01623 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
GPPMODKI_01624 4e-167 fadM E Proline dehydrogenase
GPPMODKI_01625 3.9e-43
GPPMODKI_01626 4.2e-53 yusN M Coat F domain
GPPMODKI_01627 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
GPPMODKI_01628 8.1e-288 yusP P Major facilitator superfamily
GPPMODKI_01629 3.7e-157 ywbI2 K Transcriptional regulator
GPPMODKI_01630 6.1e-137 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
GPPMODKI_01631 2.8e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPPMODKI_01632 3.3e-39 yusU S Protein of unknown function (DUF2573)
GPPMODKI_01633 3.1e-150 yusV 3.6.3.34 HP ABC transporter
GPPMODKI_01634 3.9e-43 S YusW-like protein
GPPMODKI_01635 0.0 pepF2 E COG1164 Oligoendopeptidase F
GPPMODKI_01636 1.5e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPPMODKI_01637 1.6e-79 dps P Belongs to the Dps family
GPPMODKI_01638 4.8e-241 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPPMODKI_01639 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPPMODKI_01640 1e-251 cssS 2.7.13.3 T PhoQ Sensor
GPPMODKI_01641 3.4e-24
GPPMODKI_01642 1e-157 yuxN K Transcriptional regulator
GPPMODKI_01643 3.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GPPMODKI_01644 6.6e-24 S Protein of unknown function (DUF3970)
GPPMODKI_01645 2.3e-257 gerAA EG Spore germination protein
GPPMODKI_01646 6.6e-188 gerAB E Spore germination protein
GPPMODKI_01647 6.4e-207 gerAC S Spore germination B3/ GerAC like, C-terminal
GPPMODKI_01648 9.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPPMODKI_01649 2.3e-193 vraS 2.7.13.3 T Histidine kinase
GPPMODKI_01650 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
GPPMODKI_01651 6.2e-141 liaG S Putative adhesin
GPPMODKI_01652 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
GPPMODKI_01653 3.3e-46 liaI S membrane
GPPMODKI_01654 2.8e-227 yvqJ EGP Major facilitator Superfamily
GPPMODKI_01655 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
GPPMODKI_01656 1.8e-223 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
GPPMODKI_01657 8.2e-180 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPPMODKI_01658 1.1e-167 yvrC P ABC transporter substrate-binding protein
GPPMODKI_01659 3.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPPMODKI_01660 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
GPPMODKI_01661 0.0 T PhoQ Sensor
GPPMODKI_01662 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPPMODKI_01663 1.9e-36
GPPMODKI_01664 7.1e-101 yvrI K RNA polymerase
GPPMODKI_01665 1.2e-15 S YvrJ protein family
GPPMODKI_01666 9.2e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
GPPMODKI_01667 1.4e-66 yvrL S Regulatory protein YrvL
GPPMODKI_01668 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
GPPMODKI_01669 1.2e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPPMODKI_01670 6.6e-185 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPPMODKI_01671 3.4e-177 fhuD P ABC transporter
GPPMODKI_01672 4.5e-126 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GPPMODKI_01673 2.9e-236 yvsH E Arginine ornithine antiporter
GPPMODKI_01674 3.6e-14 S Small spore protein J (Spore_SspJ)
GPPMODKI_01675 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
GPPMODKI_01676 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GPPMODKI_01677 1.7e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
GPPMODKI_01678 4.1e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
GPPMODKI_01679 2.3e-94 modB P COG4149 ABC-type molybdate transport system, permease component
GPPMODKI_01680 9.1e-113 yfiK K Regulator
GPPMODKI_01681 1.5e-179 T Histidine kinase
GPPMODKI_01682 3.6e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
GPPMODKI_01683 9.7e-192 yfiM V ABC-2 type transporter
GPPMODKI_01684 4e-196 yfiN V COG0842 ABC-type multidrug transport system, permease component
GPPMODKI_01685 5e-156 yvgN S reductase
GPPMODKI_01686 1.1e-86 yvgO
GPPMODKI_01687 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
GPPMODKI_01688 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
GPPMODKI_01689 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPPMODKI_01690 0.0 helD 3.6.4.12 L DNA helicase
GPPMODKI_01691 3.1e-99 yvgT S membrane
GPPMODKI_01692 2.6e-141 S Metallo-peptidase family M12
GPPMODKI_01693 5.6e-71 bdbC O Required for disulfide bond formation in some proteins
GPPMODKI_01694 1.2e-102 bdbD O Thioredoxin
GPPMODKI_01695 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
GPPMODKI_01696 0.0 copA 3.6.3.54 P P-type ATPase
GPPMODKI_01697 2.6e-29 copZ P Heavy-metal-associated domain
GPPMODKI_01698 3.7e-48 csoR S transcriptional
GPPMODKI_01699 3.4e-194 yvaA 1.1.1.371 S Oxidoreductase
GPPMODKI_01700 1.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPPMODKI_01701 1.2e-252 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPPMODKI_01702 5.6e-46 ytnI O COG0695 Glutaredoxin and related proteins
GPPMODKI_01703 3.2e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPPMODKI_01704 3.6e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GPPMODKI_01705 4.9e-120 tcyM U Binding-protein-dependent transport system inner membrane component
GPPMODKI_01706 1.5e-119 tcyL P Binding-protein-dependent transport system inner membrane component
GPPMODKI_01707 6e-146 tcyK M Bacterial periplasmic substrate-binding proteins
GPPMODKI_01708 6e-130 ytmJ ET Bacterial periplasmic substrate-binding proteins
GPPMODKI_01709 3e-101 ytmI K Acetyltransferase (GNAT) domain
GPPMODKI_01710 2.1e-160 ytlI K LysR substrate binding domain
GPPMODKI_01711 2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPPMODKI_01712 8.2e-48 yrdF K ribonuclease inhibitor
GPPMODKI_01713 3.2e-44 yrdF K ribonuclease inhibitor
GPPMODKI_01715 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GPPMODKI_01716 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GPPMODKI_01717 7.4e-143 est 3.1.1.1 S Carboxylesterase
GPPMODKI_01718 1.1e-23 secG U Preprotein translocase subunit SecG
GPPMODKI_01719 6e-35 yvzC K Transcriptional
GPPMODKI_01720 1e-69 K transcriptional
GPPMODKI_01721 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
GPPMODKI_01722 4.4e-52 yodB K transcriptional
GPPMODKI_01723 1.7e-257 T His Kinase A (phosphoacceptor) domain
GPPMODKI_01724 1.4e-121 K Transcriptional regulatory protein, C terminal
GPPMODKI_01725 1.1e-133 mutG S ABC-2 family transporter protein
GPPMODKI_01726 5.1e-120 spaE S ABC-2 family transporter protein
GPPMODKI_01727 1.8e-125 mutF V ABC transporter, ATP-binding protein
GPPMODKI_01728 4.7e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
GPPMODKI_01729 1.9e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GPPMODKI_01730 1.6e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
GPPMODKI_01731 3.7e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GPPMODKI_01732 9.6e-76 yvbF K Belongs to the GbsR family
GPPMODKI_01733 3.7e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
GPPMODKI_01734 2.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GPPMODKI_01735 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
GPPMODKI_01736 3.3e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GPPMODKI_01737 7.1e-98 yvbF K Belongs to the GbsR family
GPPMODKI_01738 3.4e-104 yvbG U UPF0056 membrane protein
GPPMODKI_01739 3.8e-120 exoY M Membrane
GPPMODKI_01740 0.0 tcaA S response to antibiotic
GPPMODKI_01741 8.9e-70 yvbK 3.1.3.25 K acetyltransferase
GPPMODKI_01742 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GPPMODKI_01743 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
GPPMODKI_01744 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPPMODKI_01745 2.1e-216 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GPPMODKI_01746 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GPPMODKI_01747 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GPPMODKI_01749 7.4e-253 araE EGP Major facilitator Superfamily
GPPMODKI_01750 1.2e-202 araR K transcriptional
GPPMODKI_01751 3.2e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPPMODKI_01752 5.4e-124 yvbU K Transcriptional regulator
GPPMODKI_01753 8.5e-157 yvbV EG EamA-like transporter family
GPPMODKI_01754 3.8e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
GPPMODKI_01756 5.5e-150 ybbH_1 K RpiR family transcriptional regulator
GPPMODKI_01757 9.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
GPPMODKI_01758 3.1e-224 gntP EG COG2610 H gluconate symporter and related permeases
GPPMODKI_01760 1.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GPPMODKI_01761 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
GPPMODKI_01762 9.3e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GPPMODKI_01763 9.8e-222 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPPMODKI_01764 3e-120 yvfI K COG2186 Transcriptional regulators
GPPMODKI_01765 5e-304 yvfH C L-lactate permease
GPPMODKI_01766 3.2e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
GPPMODKI_01767 2.7e-32 yvfG S YvfG protein
GPPMODKI_01768 1e-184 yvfF GM Exopolysaccharide biosynthesis protein
GPPMODKI_01769 1.6e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
GPPMODKI_01770 3.5e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
GPPMODKI_01771 9.8e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GPPMODKI_01772 1.3e-271 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPPMODKI_01773 6.8e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
GPPMODKI_01774 3.7e-204 epsI GM pyruvyl transferase
GPPMODKI_01775 3.2e-192 epsH GT2 S Glycosyltransferase like family 2
GPPMODKI_01776 7.7e-205 epsG S EpsG family
GPPMODKI_01777 1e-212 epsF GT4 M Glycosyl transferases group 1
GPPMODKI_01778 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GPPMODKI_01779 2.6e-219 epsD GT4 M Glycosyl transferase 4-like
GPPMODKI_01780 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
GPPMODKI_01781 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
GPPMODKI_01782 1.2e-118 ywqC M biosynthesis protein
GPPMODKI_01783 5.1e-78 slr K transcriptional
GPPMODKI_01784 5.1e-281 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
GPPMODKI_01786 9.8e-97 ywjB H RibD C-terminal domain
GPPMODKI_01787 1.5e-112 yyaS S Membrane
GPPMODKI_01788 2.4e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPPMODKI_01789 1.6e-93 padC Q Phenolic acid decarboxylase
GPPMODKI_01790 6.1e-55 MA20_18690 S Protein of unknown function (DUF3237)
GPPMODKI_01791 6e-14 S Protein of unknown function (DUF1433)
GPPMODKI_01792 7e-40 S Protein of unknown function (DUF1433)
GPPMODKI_01793 6e-234 I Pfam Lipase (class 3)
GPPMODKI_01794 3.1e-34
GPPMODKI_01796 6.3e-295 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
GPPMODKI_01797 1.5e-217 rafB P LacY proton/sugar symporter
GPPMODKI_01798 1.9e-183 scrR K transcriptional
GPPMODKI_01799 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GPPMODKI_01800 1.1e-97 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
GPPMODKI_01801 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
GPPMODKI_01802 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
GPPMODKI_01803 1.5e-102 malA S Protein of unknown function (DUF1189)
GPPMODKI_01804 2.3e-140 malD P transport
GPPMODKI_01805 3.1e-221 malC P COG1175 ABC-type sugar transport systems, permease components
GPPMODKI_01806 1.2e-206 mdxE G COG2182 Maltose-binding periplasmic proteins domains
GPPMODKI_01807 4.9e-311 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
GPPMODKI_01808 1.6e-161 yvdE K Transcriptional regulator
GPPMODKI_01809 3.4e-103 yvdD 3.2.2.10 S Belongs to the LOG family
GPPMODKI_01810 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
GPPMODKI_01811 1.9e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
GPPMODKI_01812 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
GPPMODKI_01813 4.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPPMODKI_01814 3.5e-79 M Ribonuclease
GPPMODKI_01815 7.4e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
GPPMODKI_01816 2.3e-35 crh G Phosphocarrier protein Chr
GPPMODKI_01817 3.1e-170 whiA K May be required for sporulation
GPPMODKI_01818 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GPPMODKI_01819 1.1e-166 rapZ S Displays ATPase and GTPase activities
GPPMODKI_01820 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GPPMODKI_01821 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GPPMODKI_01822 3.7e-111 usp CBM50 M protein conserved in bacteria
GPPMODKI_01823 1.4e-19 S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GPPMODKI_01824 1.6e-245 S COG0457 FOG TPR repeat
GPPMODKI_01825 8e-191 sasA T Histidine kinase
GPPMODKI_01826 1.9e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPPMODKI_01827 1e-57
GPPMODKI_01828 0.0 msbA2 3.6.3.44 V ABC transporter
GPPMODKI_01829 3.1e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
GPPMODKI_01830 1.8e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GPPMODKI_01831 3.2e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPPMODKI_01832 8.1e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPPMODKI_01833 9.7e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
GPPMODKI_01834 3.2e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPPMODKI_01835 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GPPMODKI_01836 1e-207 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GPPMODKI_01837 1.2e-137 yvpB NU protein conserved in bacteria
GPPMODKI_01838 1.2e-83 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
GPPMODKI_01839 2.4e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
GPPMODKI_01840 1.2e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPPMODKI_01841 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GPPMODKI_01842 1.4e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPPMODKI_01843 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GPPMODKI_01844 1.1e-133 yvoA K transcriptional
GPPMODKI_01845 4.7e-105 yxaF K Transcriptional regulator
GPPMODKI_01846 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
GPPMODKI_01847 3.9e-41 yvlD S Membrane
GPPMODKI_01848 9.6e-26 pspB KT PspC domain
GPPMODKI_01849 1.6e-165 yvlB S Putative adhesin
GPPMODKI_01850 6.1e-49 yvlA
GPPMODKI_01851 3e-38 yvkN
GPPMODKI_01852 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GPPMODKI_01853 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GPPMODKI_01854 7.6e-33 csbA S protein conserved in bacteria
GPPMODKI_01855 0.0 yvkC 2.7.9.2 GT Phosphotransferase
GPPMODKI_01856 7e-110 yvkB K Transcriptional regulator
GPPMODKI_01857 5.1e-227 yvkA EGP Major facilitator Superfamily
GPPMODKI_01858 5.5e-27 bacT Q Thioesterase domain
GPPMODKI_01860 9.5e-176 S Psort location CytoplasmicMembrane, score
GPPMODKI_01861 4.3e-51 E Saccharopine dehydrogenase
GPPMODKI_01862 1.4e-99 V ABC transporter transmembrane region
GPPMODKI_01863 0.0 Q TIGRFAM amino acid adenylation domain
GPPMODKI_01864 0.0 fusAA Q Non-ribosomal peptide synthetase modules and related proteins
GPPMODKI_01865 4.4e-65 IQ KR domain
GPPMODKI_01867 8.6e-20 L Transposase and inactivated derivatives
GPPMODKI_01869 5.9e-219 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPPMODKI_01870 1.5e-55 swrA S Swarming motility protein
GPPMODKI_01871 3.3e-253 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
GPPMODKI_01872 1.8e-227 ywoF P Right handed beta helix region
GPPMODKI_01873 9.2e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GPPMODKI_01874 1e-122 ftsE D cell division ATP-binding protein FtsE
GPPMODKI_01875 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
GPPMODKI_01876 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
GPPMODKI_01877 5.1e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GPPMODKI_01878 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GPPMODKI_01879 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPPMODKI_01880 6.8e-68
GPPMODKI_01881 5.9e-10 fliT S bacterial-type flagellum organization
GPPMODKI_01882 3e-66 fliS N flagellar protein FliS
GPPMODKI_01883 6.2e-245 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPPMODKI_01884 2.1e-100 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPPMODKI_01885 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GPPMODKI_01886 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GPPMODKI_01887 3.4e-79 yviE
GPPMODKI_01888 6.1e-163 flgL N Belongs to the bacterial flagellin family
GPPMODKI_01889 2.8e-274 flgK N flagellar hook-associated protein
GPPMODKI_01890 8.9e-81 flgN NOU FlgN protein
GPPMODKI_01891 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
GPPMODKI_01892 2.4e-74 yvyF S flagellar protein
GPPMODKI_01893 4.5e-77 comFC S Phosphoribosyl transferase domain
GPPMODKI_01894 1.7e-42 comFB S Late competence development protein ComFB
GPPMODKI_01895 4e-259 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GPPMODKI_01896 1.4e-158 degV S protein conserved in bacteria
GPPMODKI_01897 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPPMODKI_01898 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
GPPMODKI_01899 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
GPPMODKI_01900 3.9e-170 yvhJ K Transcriptional regulator
GPPMODKI_01901 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
GPPMODKI_01902 6.8e-239 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
GPPMODKI_01903 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
GPPMODKI_01904 1.2e-115 tuaF M protein involved in exopolysaccharide biosynthesis
GPPMODKI_01905 8.6e-257 tuaE M Teichuronic acid biosynthesis protein
GPPMODKI_01906 2.5e-250 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPPMODKI_01907 2.2e-221 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
GPPMODKI_01908 2.7e-258 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPPMODKI_01909 1.4e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GPPMODKI_01910 5.4e-270 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GPPMODKI_01911 0.0 lytB 3.5.1.28 D Stage II sporulation protein
GPPMODKI_01912 1.3e-48
GPPMODKI_01913 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
GPPMODKI_01914 1.2e-208 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GPPMODKI_01915 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GPPMODKI_01916 4.6e-280 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GPPMODKI_01917 1.7e-151 tagG GM Transport permease protein
GPPMODKI_01918 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GPPMODKI_01919 1.8e-292 M Glycosyltransferase like family 2
GPPMODKI_01920 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
GPPMODKI_01921 6.5e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GPPMODKI_01922 2.6e-219 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GPPMODKI_01923 3.8e-242 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPPMODKI_01924 1.1e-183 pmi 5.3.1.8 G mannose-6-phosphate isomerase
GPPMODKI_01925 5.7e-264 gerBA EG Spore germination protein
GPPMODKI_01926 1.5e-195 gerBB E Spore germination protein
GPPMODKI_01927 2.5e-211 gerAC S Spore germination protein
GPPMODKI_01928 4e-267 GT2,GT4 J Glycosyl transferase family 2
GPPMODKI_01929 1.1e-248 ywtG EGP Major facilitator Superfamily
GPPMODKI_01930 7.2e-178 ywtF K Transcriptional regulator
GPPMODKI_01931 1.6e-157 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
GPPMODKI_01932 1.3e-35 yttA 2.7.13.3 S Pfam Transposase IS66
GPPMODKI_01933 2e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GPPMODKI_01934 1.3e-20 ywtC
GPPMODKI_01935 1.2e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
GPPMODKI_01936 2.3e-70 pgsC S biosynthesis protein
GPPMODKI_01937 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
GPPMODKI_01938 5.9e-184 gerKA EG Spore germination protein
GPPMODKI_01939 6.7e-193 gerKB E Spore germination protein
GPPMODKI_01940 1.3e-202 gerKC S Spore germination B3/ GerAC like, C-terminal
GPPMODKI_01941 5e-179 rbsR K transcriptional
GPPMODKI_01942 5.7e-158 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPPMODKI_01943 8.1e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GPPMODKI_01944 1.4e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
GPPMODKI_01945 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
GPPMODKI_01946 1.3e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
GPPMODKI_01947 5.2e-90 batE T Sh3 type 3 domain protein
GPPMODKI_01948 1.8e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
GPPMODKI_01949 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
GPPMODKI_01950 8.9e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GPPMODKI_01951 2e-166 alsR K LysR substrate binding domain
GPPMODKI_01952 9.9e-239 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPPMODKI_01953 4.4e-126 ywrJ
GPPMODKI_01954 9.2e-132 cotB
GPPMODKI_01955 5e-212 cotH M Spore Coat
GPPMODKI_01956 2.2e-09
GPPMODKI_01957 3.3e-112 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GPPMODKI_01958 3.6e-07 S Domain of unknown function (DUF4181)
GPPMODKI_01959 1.4e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
GPPMODKI_01960 1.1e-83 ywrC K Transcriptional regulator
GPPMODKI_01961 3.9e-102 ywrB P Chromate transporter
GPPMODKI_01962 2.2e-88 ywrA P COG2059 Chromate transport protein ChrA
GPPMODKI_01964 3.9e-93 ywqN S NAD(P)H-dependent
GPPMODKI_01965 1.8e-156 K Transcriptional regulator
GPPMODKI_01966 1.4e-130 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
GPPMODKI_01967 1.3e-95
GPPMODKI_01969 3.6e-50
GPPMODKI_01970 1.2e-88
GPPMODKI_01971 7.1e-34 M COG3209 Rhs family protein
GPPMODKI_01972 6.8e-58 T DNase/tRNase domain of colicin-like bacteriocin
GPPMODKI_01973 2e-49
GPPMODKI_01974 0.0 ywqJ S Pre-toxin TG
GPPMODKI_01975 4.3e-37 ywqI S Family of unknown function (DUF5344)
GPPMODKI_01976 1.9e-21 S Domain of unknown function (DUF5082)
GPPMODKI_01978 1.1e-149 ywqG S Domain of unknown function (DUF1963)
GPPMODKI_01979 2e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPPMODKI_01980 1.2e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
GPPMODKI_01981 5.7e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
GPPMODKI_01982 1.5e-111 ywqC M biosynthesis protein
GPPMODKI_01983 1.3e-14
GPPMODKI_01984 6.6e-306 ywqB S SWIM zinc finger
GPPMODKI_01985 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
GPPMODKI_01986 3e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
GPPMODKI_01987 7.5e-138 glcR K DeoR C terminal sensor domain
GPPMODKI_01988 1.3e-57 ssbB L Single-stranded DNA-binding protein
GPPMODKI_01989 4e-62 ywpG
GPPMODKI_01990 2.5e-68 ywpF S YwpF-like protein
GPPMODKI_01991 1.1e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GPPMODKI_01992 8.4e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GPPMODKI_01993 2.5e-200 S aspartate phosphatase
GPPMODKI_01994 1.1e-142 flhP N flagellar basal body
GPPMODKI_01995 3.2e-128 flhO N flagellar basal body
GPPMODKI_01996 2.7e-180 mbl D Rod shape-determining protein
GPPMODKI_01997 1.8e-44 spoIIID K Stage III sporulation protein D
GPPMODKI_01998 8.5e-72 ywoH K transcriptional
GPPMODKI_01999 4.9e-213 ywoG EGP Major facilitator Superfamily
GPPMODKI_02000 1.6e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
GPPMODKI_02001 3.6e-244 ywoD EGP Major facilitator superfamily
GPPMODKI_02002 5.7e-103 phzA Q Isochorismatase family
GPPMODKI_02003 2.5e-228 amt P Ammonium transporter
GPPMODKI_02004 1.7e-57 nrgB K Belongs to the P(II) protein family
GPPMODKI_02005 1.1e-209 ftsW D Belongs to the SEDS family
GPPMODKI_02006 9.3e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
GPPMODKI_02007 3.3e-71 ywnJ S VanZ like family
GPPMODKI_02008 8.4e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
GPPMODKI_02009 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
GPPMODKI_02010 1.2e-10 ywnC S Family of unknown function (DUF5362)
GPPMODKI_02011 4.2e-69 ywnF S Family of unknown function (DUF5392)
GPPMODKI_02012 8.4e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPPMODKI_02013 4.8e-53 ywnC S Family of unknown function (DUF5362)
GPPMODKI_02014 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
GPPMODKI_02015 1.8e-66 ywnA K Transcriptional regulator
GPPMODKI_02016 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GPPMODKI_02017 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
GPPMODKI_02018 3.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
GPPMODKI_02019 7.4e-10 csbD K CsbD-like
GPPMODKI_02020 3.6e-82 ywmF S Peptidase M50
GPPMODKI_02021 4.8e-93 S response regulator aspartate phosphatase
GPPMODKI_02022 4.1e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPPMODKI_02023 1.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPPMODKI_02025 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
GPPMODKI_02026 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
GPPMODKI_02027 2.8e-188 spoIID D Stage II sporulation protein D
GPPMODKI_02028 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPPMODKI_02029 5.3e-133 ywmB S TATA-box binding
GPPMODKI_02030 1.3e-32 ywzB S membrane
GPPMODKI_02031 3.5e-90 ywmA
GPPMODKI_02032 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GPPMODKI_02033 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPPMODKI_02034 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPPMODKI_02035 4.1e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPPMODKI_02036 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPPMODKI_02037 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPPMODKI_02038 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPPMODKI_02039 9.3e-130 atpB C it plays a direct role in the translocation of protons across the membrane
GPPMODKI_02040 2.1e-61 atpI S ATP synthase
GPPMODKI_02041 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPPMODKI_02042 7.3e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPPMODKI_02043 5.9e-97 ywlG S Belongs to the UPF0340 family
GPPMODKI_02044 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
GPPMODKI_02045 6.2e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPPMODKI_02046 4.5e-84 mntP P Probably functions as a manganese efflux pump
GPPMODKI_02047 1.1e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GPPMODKI_02048 3.9e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
GPPMODKI_02049 4.4e-110 spoIIR S stage II sporulation protein R
GPPMODKI_02050 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
GPPMODKI_02052 1.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GPPMODKI_02053 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPPMODKI_02054 5.8e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPPMODKI_02055 1.3e-94 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
GPPMODKI_02056 3.6e-158 ywkB S Membrane transport protein
GPPMODKI_02057 0.0 sfcA 1.1.1.38 C malic enzyme
GPPMODKI_02058 1.4e-104 tdk 2.7.1.21 F thymidine kinase
GPPMODKI_02059 1.1e-32 rpmE J Binds the 23S rRNA
GPPMODKI_02060 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPPMODKI_02061 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
GPPMODKI_02062 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPPMODKI_02063 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPPMODKI_02064 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
GPPMODKI_02065 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
GPPMODKI_02066 4.9e-93 ywjG S Domain of unknown function (DUF2529)
GPPMODKI_02067 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GPPMODKI_02068 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GPPMODKI_02069 0.0 fadF C COG0247 Fe-S oxidoreductase
GPPMODKI_02070 3e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
GPPMODKI_02071 6.1e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
GPPMODKI_02072 4.2e-43 ywjC
GPPMODKI_02073 0.0 ywjA V ABC transporter
GPPMODKI_02074 1.3e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPPMODKI_02075 4.9e-103 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPPMODKI_02076 1.5e-123 narI 1.7.5.1 C nitrate reductase, gamma
GPPMODKI_02077 5.6e-95 narJ 1.7.5.1 C nitrate reductase
GPPMODKI_02078 4.8e-295 narH 1.7.5.1 C Nitrate reductase, beta
GPPMODKI_02079 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GPPMODKI_02080 1e-84 arfM T cyclic nucleotide binding
GPPMODKI_02081 1e-136 ywiC S YwiC-like protein
GPPMODKI_02082 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
GPPMODKI_02083 5.8e-214 narK P COG2223 Nitrate nitrite transporter
GPPMODKI_02084 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
GPPMODKI_02085 1.2e-73 ywiB S protein conserved in bacteria
GPPMODKI_02087 7.8e-231 ywhL CO amine dehydrogenase activity
GPPMODKI_02088 8.5e-222 ywhK CO amine dehydrogenase activity
GPPMODKI_02089 2.4e-76 S aspartate phosphatase
GPPMODKI_02091 9.7e-29 ydcG K sequence-specific DNA binding
GPPMODKI_02092 5e-33
GPPMODKI_02093 2e-28 S Domain of unknown function (DUF4177)
GPPMODKI_02095 3.1e-76 CP Membrane
GPPMODKI_02098 5.4e-169 speB 3.5.3.11 E Belongs to the arginase family
GPPMODKI_02099 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GPPMODKI_02100 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GPPMODKI_02101 2.3e-80
GPPMODKI_02102 1.4e-95 ywhD S YwhD family
GPPMODKI_02103 1.2e-117 ywhC S Peptidase family M50
GPPMODKI_02104 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
GPPMODKI_02105 8e-70 ywhA K Transcriptional regulator
GPPMODKI_02106 2e-246 yhdG_1 E C-terminus of AA_permease
GPPMODKI_02107 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
GPPMODKI_02108 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
GPPMODKI_02109 6.9e-36 ywzC S Belongs to the UPF0741 family
GPPMODKI_02110 3e-110 rsfA_1
GPPMODKI_02111 5.3e-50 padR K PadR family transcriptional regulator
GPPMODKI_02112 4.4e-92 S membrane
GPPMODKI_02113 1.9e-164 V ABC transporter, ATP-binding protein
GPPMODKI_02114 2.9e-168 yhcI S ABC transporter (permease)
GPPMODKI_02117 1.9e-183
GPPMODKI_02119 1.6e-157 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
GPPMODKI_02120 5.1e-162 cysL K Transcriptional regulator
GPPMODKI_02121 3.3e-159 MA20_14895 S Conserved hypothetical protein 698
GPPMODKI_02122 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
GPPMODKI_02123 1.1e-146 ywfI C May function as heme-dependent peroxidase
GPPMODKI_02124 8.2e-140 IQ Enoyl-(Acyl carrier protein) reductase
GPPMODKI_02125 7.8e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
GPPMODKI_02126 4.7e-208 bacE EGP Major facilitator Superfamily
GPPMODKI_02127 4.4e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
GPPMODKI_02128 1.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPPMODKI_02129 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
GPPMODKI_02130 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
GPPMODKI_02131 7.1e-223 ywfA EGP Major facilitator Superfamily
GPPMODKI_02132 3.4e-206 tcaB EGP Major facilitator Superfamily
GPPMODKI_02133 7.5e-261 lysP E amino acid
GPPMODKI_02134 0.0 rocB E arginine degradation protein
GPPMODKI_02135 2.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
GPPMODKI_02136 2.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
GPPMODKI_02137 3.5e-158 T PhoQ Sensor
GPPMODKI_02138 8.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPPMODKI_02139 1.6e-75
GPPMODKI_02140 1.1e-119 S ABC-2 family transporter protein
GPPMODKI_02141 4.3e-172 bcrA5 V ABC transporter, ATP-binding protein
GPPMODKI_02142 3.5e-87 spsL 5.1.3.13 M Spore Coat
GPPMODKI_02143 3.6e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GPPMODKI_02144 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GPPMODKI_02145 1.2e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPPMODKI_02146 2.6e-183 spsG M Spore Coat
GPPMODKI_02147 6.9e-133 spsF M Spore Coat
GPPMODKI_02148 9.9e-216 spsE 2.5.1.56 M acid synthase
GPPMODKI_02149 2.1e-157 spsD 2.3.1.210 K Spore Coat
GPPMODKI_02150 1.3e-221 spsC E Belongs to the DegT DnrJ EryC1 family
GPPMODKI_02151 3.1e-275 spsB M Capsule polysaccharide biosynthesis protein
GPPMODKI_02152 2.6e-143 spsA M Spore Coat
GPPMODKI_02153 2.3e-54 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
GPPMODKI_02154 4.2e-46 ywdK S small membrane protein
GPPMODKI_02155 1.7e-230 ywdJ F Xanthine uracil
GPPMODKI_02156 5.8e-38 ywdI S Family of unknown function (DUF5327)
GPPMODKI_02157 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPPMODKI_02158 5e-153 ywdF GT2,GT4 S Glycosyltransferase like family 2
GPPMODKI_02160 9.9e-88 ywdD
GPPMODKI_02161 6.3e-57 pex K Transcriptional regulator PadR-like family
GPPMODKI_02162 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPPMODKI_02163 9.7e-20 ywdA
GPPMODKI_02164 1.6e-282 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
GPPMODKI_02165 3.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPPMODKI_02166 4.4e-07 sacT K transcriptional antiterminator
GPPMODKI_02167 1.8e-150 sacT K transcriptional antiterminator
GPPMODKI_02169 0.0 vpr O Belongs to the peptidase S8 family
GPPMODKI_02170 8.1e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPPMODKI_02171 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
GPPMODKI_02172 2.8e-208 rodA D Belongs to the SEDS family
GPPMODKI_02173 2.8e-80 ysnE K acetyltransferase
GPPMODKI_02174 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
GPPMODKI_02175 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
GPPMODKI_02176 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
GPPMODKI_02177 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPPMODKI_02178 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
GPPMODKI_02179 4.2e-26 ywzA S membrane
GPPMODKI_02180 9.5e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GPPMODKI_02181 1.7e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPPMODKI_02182 2.3e-61 gtcA S GtrA-like protein
GPPMODKI_02183 4.3e-112 ywcC K Bacterial regulatory proteins, tetR family
GPPMODKI_02185 3.6e-128 H Methionine biosynthesis protein MetW
GPPMODKI_02186 5.3e-132 S Streptomycin biosynthesis protein StrF
GPPMODKI_02187 2.7e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
GPPMODKI_02188 1e-240 ywbN P Dyp-type peroxidase family protein
GPPMODKI_02189 9.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GPPMODKI_02190 1.1e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GPPMODKI_02191 8.2e-152 ywbI K Transcriptional regulator
GPPMODKI_02192 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
GPPMODKI_02193 3.4e-110 ywbG M effector of murein hydrolase
GPPMODKI_02194 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
GPPMODKI_02195 9.3e-141 mta K transcriptional
GPPMODKI_02196 1.5e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
GPPMODKI_02197 1.8e-223 ywbD 2.1.1.191 J Methyltransferase
GPPMODKI_02198 7.6e-67 ywbC 4.4.1.5 E glyoxalase
GPPMODKI_02199 3.2e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPPMODKI_02200 1.2e-263 epr 3.4.21.62 O Belongs to the peptidase S8 family
GPPMODKI_02201 1.1e-163 gspA M General stress
GPPMODKI_02202 1.6e-48 ywaE K Transcriptional regulator
GPPMODKI_02203 4.3e-196 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPPMODKI_02204 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
GPPMODKI_02205 1.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
GPPMODKI_02206 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
GPPMODKI_02207 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPPMODKI_02208 1.1e-228 dltB M membrane protein involved in D-alanine export
GPPMODKI_02209 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPPMODKI_02210 4.1e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GPPMODKI_02211 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
GPPMODKI_02212 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GPPMODKI_02213 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
GPPMODKI_02214 1.4e-248 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPPMODKI_02215 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
GPPMODKI_02216 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
GPPMODKI_02218 3.6e-108 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
GPPMODKI_02219 4.3e-173 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPPMODKI_02220 1.3e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPPMODKI_02221 4e-167 cbrA3 P Periplasmic binding protein
GPPMODKI_02222 2e-58 arsR K transcriptional
GPPMODKI_02223 5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPPMODKI_02224 6.9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
GPPMODKI_02225 2.9e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
GPPMODKI_02226 5.4e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPPMODKI_02227 1.3e-286 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GPPMODKI_02228 6.9e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
GPPMODKI_02229 1.5e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
GPPMODKI_02230 1.6e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
GPPMODKI_02231 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
GPPMODKI_02232 6.1e-193 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
GPPMODKI_02233 3.6e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
GPPMODKI_02234 6.5e-156 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPPMODKI_02235 3.8e-291 cydD V ATP-binding protein
GPPMODKI_02236 0.0 cydD V ATP-binding
GPPMODKI_02237 5.5e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
GPPMODKI_02238 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
GPPMODKI_02239 2.6e-215 cimH C COG3493 Na citrate symporter
GPPMODKI_02240 1e-156 yxkH G Polysaccharide deacetylase
GPPMODKI_02241 7e-206 msmK P Belongs to the ABC transporter superfamily
GPPMODKI_02242 3.7e-165 lrp QT PucR C-terminal helix-turn-helix domain
GPPMODKI_02243 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPPMODKI_02244 3.8e-87 yxkC S Domain of unknown function (DUF4352)
GPPMODKI_02245 3.9e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GPPMODKI_02246 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GPPMODKI_02249 9.1e-86 yxjI S LURP-one-related
GPPMODKI_02250 1.1e-217 yxjG 2.1.1.14 E Methionine synthase
GPPMODKI_02251 1.3e-154 rlmA 2.1.1.187 Q Methyltransferase domain
GPPMODKI_02252 3.9e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPPMODKI_02253 6.6e-74 T Domain of unknown function (DUF4163)
GPPMODKI_02254 1.4e-50 yxiS
GPPMODKI_02255 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
GPPMODKI_02256 4.7e-222 citH C Citrate transporter
GPPMODKI_02257 1.2e-142 exoK GH16 M licheninase activity
GPPMODKI_02258 3.1e-150 licT K transcriptional antiterminator
GPPMODKI_02259 3.9e-221 yxiO S COG2270 Permeases of the major facilitator superfamily
GPPMODKI_02260 1.3e-260 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
GPPMODKI_02261 1.3e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
GPPMODKI_02262 1.2e-147 yxxF EG EamA-like transporter family
GPPMODKI_02263 4.1e-72 yxiE T Belongs to the universal stress protein A family
GPPMODKI_02264 0.0 L HKD family nuclease
GPPMODKI_02265 1.2e-64 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GPPMODKI_02266 1.6e-171 3.6.4.12 L AAA domain
GPPMODKI_02267 9.6e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
GPPMODKI_02268 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
GPPMODKI_02269 7.3e-286 hutH 4.3.1.3 E Histidine ammonia-lyase
GPPMODKI_02270 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GPPMODKI_02271 2.3e-237 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
GPPMODKI_02272 6.5e-176 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
GPPMODKI_02273 7.5e-253 lysP E amino acid
GPPMODKI_02274 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
GPPMODKI_02275 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPPMODKI_02276 3.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPPMODKI_02277 5.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GPPMODKI_02278 1.8e-150 yidA S hydrolases of the HAD superfamily
GPPMODKI_02281 2.3e-07 yxeE
GPPMODKI_02282 8.4e-23 yxeD
GPPMODKI_02283 6e-35
GPPMODKI_02284 2.4e-178 fhuD P Periplasmic binding protein
GPPMODKI_02285 1.3e-57 yxeA S Protein of unknown function (DUF1093)
GPPMODKI_02286 0.0 yxdM V ABC transporter (permease)
GPPMODKI_02287 5.5e-141 yxdL V ABC transporter, ATP-binding protein
GPPMODKI_02288 6e-177 T PhoQ Sensor
GPPMODKI_02289 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPPMODKI_02290 2.3e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
GPPMODKI_02291 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
GPPMODKI_02292 5.6e-166 iolH G Xylose isomerase-like TIM barrel
GPPMODKI_02293 2.3e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
GPPMODKI_02294 6.2e-230 iolF EGP Major facilitator Superfamily
GPPMODKI_02295 8e-176 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
GPPMODKI_02296 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
GPPMODKI_02297 4.4e-183 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
GPPMODKI_02298 1.7e-156 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
GPPMODKI_02299 2.1e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPPMODKI_02300 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
GPPMODKI_02301 4.9e-176 iolS C Aldo keto reductase
GPPMODKI_02302 6.7e-246 csbC EGP Major facilitator Superfamily
GPPMODKI_02303 0.0 htpG O Molecular chaperone. Has ATPase activity
GPPMODKI_02305 4.8e-151 IQ Enoyl-(Acyl carrier protein) reductase
GPPMODKI_02306 6.7e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPPMODKI_02307 1.9e-198 desK 2.7.13.3 T Histidine kinase
GPPMODKI_02308 1.8e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
GPPMODKI_02309 1.2e-216 yxbF K Bacterial regulatory proteins, tetR family
GPPMODKI_02310 1e-25 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
GPPMODKI_02311 6.1e-16 ygzD K transcriptional
GPPMODKI_02316 7.8e-233 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GPPMODKI_02317 6.2e-109 M HlyD family secretion protein
GPPMODKI_02318 3.4e-247 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
GPPMODKI_02319 1.8e-141 S PQQ-like domain
GPPMODKI_02320 9.5e-63 S Family of unknown function (DUF5391)
GPPMODKI_02321 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
GPPMODKI_02322 1.2e-203 EGP Major facilitator Superfamily
GPPMODKI_02323 1.5e-74 yxaI S membrane protein domain
GPPMODKI_02324 1.6e-120 E Ring-cleavage extradiol dioxygenase
GPPMODKI_02325 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
GPPMODKI_02326 2.3e-287 ahpF O Alkyl hydroperoxide reductase
GPPMODKI_02327 1.2e-227 XK27_00240 S Fic/DOC family
GPPMODKI_02328 3.2e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
GPPMODKI_02329 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
GPPMODKI_02330 1.1e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
GPPMODKI_02331 1.8e-153 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
GPPMODKI_02332 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
GPPMODKI_02333 3.3e-88 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
GPPMODKI_02334 2.2e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GPPMODKI_02335 1.9e-181 S Fusaric acid resistance protein-like
GPPMODKI_02336 3.2e-18
GPPMODKI_02337 0.0 L AAA domain
GPPMODKI_02338 9.5e-179 S Protein of unknown function DUF262
GPPMODKI_02339 8e-140 S FRG
GPPMODKI_02340 9.8e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPPMODKI_02341 7.9e-08 S YyzF-like protein
GPPMODKI_02343 1.1e-217 yycP
GPPMODKI_02344 1.4e-133 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GPPMODKI_02345 5.1e-184 C oxidoreductases (related to aryl-alcohol dehydrogenases)
GPPMODKI_02346 3.7e-87 yycN 2.3.1.128 K Acetyltransferase
GPPMODKI_02348 4.9e-199 S Histidine kinase
GPPMODKI_02349 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
GPPMODKI_02350 1e-257 rocE E amino acid
GPPMODKI_02351 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
GPPMODKI_02352 2.8e-58 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
GPPMODKI_02353 2.2e-42 sdpR K transcriptional
GPPMODKI_02354 2.4e-259 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
GPPMODKI_02355 2.2e-144 1.14.11.27 P peptidyl-arginine hydroxylation
GPPMODKI_02356 5.1e-306 S ABC transporter
GPPMODKI_02357 9.9e-198 S Major Facilitator Superfamily
GPPMODKI_02358 5e-259
GPPMODKI_02359 2.7e-188 2.7.7.73, 2.7.7.80 H ThiF family
GPPMODKI_02360 6.6e-249 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
GPPMODKI_02361 2.2e-93 K PFAM response regulator receiver
GPPMODKI_02362 1.6e-62 S Peptidase propeptide and YPEB domain
GPPMODKI_02363 3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPPMODKI_02364 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
GPPMODKI_02365 1.9e-150 yycI S protein conserved in bacteria
GPPMODKI_02366 1.6e-260 yycH S protein conserved in bacteria
GPPMODKI_02367 0.0 vicK 2.7.13.3 T Histidine kinase
GPPMODKI_02368 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPPMODKI_02373 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPPMODKI_02374 3.8e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPPMODKI_02375 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GPPMODKI_02376 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
GPPMODKI_02378 4.6e-17 yycC K YycC-like protein
GPPMODKI_02379 1e-258 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPPMODKI_02380 6.2e-238 M Glycosyltransferase Family 4
GPPMODKI_02381 9.7e-205 S Ecdysteroid kinase
GPPMODKI_02382 9.1e-236 S Carbamoyl-phosphate synthase L chain, ATP binding domain
GPPMODKI_02383 1.3e-235 M Glycosyltransferase Family 4
GPPMODKI_02384 2.7e-120 S GlcNAc-PI de-N-acetylase
GPPMODKI_02385 3.6e-89 KLT COG0515 Serine threonine protein kinase
GPPMODKI_02386 4.9e-73 rplI J binds to the 23S rRNA
GPPMODKI_02387 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GPPMODKI_02388 9.3e-159 yybS S membrane
GPPMODKI_02390 3.2e-84 cotF M Spore coat protein
GPPMODKI_02391 2.8e-66 ydeP3 K Transcriptional regulator
GPPMODKI_02392 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
GPPMODKI_02393 8.2e-166 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GPPMODKI_02394 6.5e-273 sacB 2.4.1.10 GH68 M levansucrase activity
GPPMODKI_02395 1.1e-308 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
GPPMODKI_02396 1.8e-116 K FCD domain
GPPMODKI_02397 1.6e-75 dinB S PFAM DinB family protein
GPPMODKI_02398 1.7e-160 G Major Facilitator Superfamily
GPPMODKI_02400 2.4e-54 ypaA S Protein of unknown function (DUF1304)
GPPMODKI_02401 9.6e-115 drgA C nitroreductase
GPPMODKI_02402 4.1e-69 ydgJ K Winged helix DNA-binding domain
GPPMODKI_02403 1.4e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
GPPMODKI_02404 1e-76 yybA 2.3.1.57 K transcriptional
GPPMODKI_02405 6.5e-75 yjcF S Acetyltransferase (GNAT) domain
GPPMODKI_02406 3.7e-162 eaeH M Domain of Unknown Function (DUF1259)
GPPMODKI_02407 1.2e-40 3.1.3.18 S glycolate biosynthetic process
GPPMODKI_02408 1.7e-46 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
GPPMODKI_02409 4.5e-97
GPPMODKI_02410 3.5e-66 S Leucine-rich repeat (LRR) protein
GPPMODKI_02411 4.2e-19
GPPMODKI_02412 8e-68 isp O Belongs to the peptidase S8 family
GPPMODKI_02413 9.4e-251 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPPMODKI_02414 6.5e-130 ydfC EG EamA-like transporter family
GPPMODKI_02415 1.2e-121 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
GPPMODKI_02417 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
GPPMODKI_02418 3.5e-163 yyaK S CAAX protease self-immunity
GPPMODKI_02419 3.4e-247 ydjK G Sugar (and other) transporter
GPPMODKI_02420 2.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPPMODKI_02421 4.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
GPPMODKI_02422 3.1e-144 xth 3.1.11.2 L exodeoxyribonuclease III
GPPMODKI_02423 1.6e-97 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPPMODKI_02424 3.7e-105 adaA 3.2.2.21 K Transcriptional regulator
GPPMODKI_02425 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPPMODKI_02426 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GPPMODKI_02427 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
GPPMODKI_02428 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GPPMODKI_02429 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GPPMODKI_02430 6.6e-33 yyzM S protein conserved in bacteria
GPPMODKI_02431 1.5e-175 yyaD S Membrane
GPPMODKI_02432 1.4e-110 yyaC S Sporulation protein YyaC
GPPMODKI_02433 6.7e-148 spo0J K Belongs to the ParB family
GPPMODKI_02434 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
GPPMODKI_02435 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
GPPMODKI_02436 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
GPPMODKI_02437 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GPPMODKI_02438 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPPMODKI_02439 1.3e-108 jag S single-stranded nucleic acid binding R3H
GPPMODKI_02440 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPPMODKI_02441 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GPPMODKI_02442 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPPMODKI_02443 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GPPMODKI_02444 2.4e-33 yaaA S S4 domain
GPPMODKI_02445 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPPMODKI_02446 8.1e-38 yaaB S Domain of unknown function (DUF370)
GPPMODKI_02447 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPPMODKI_02448 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPPMODKI_02452 3.9e-218 glcP G Major Facilitator Superfamily
GPPMODKI_02453 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPPMODKI_02454 2.8e-179 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
GPPMODKI_02455 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
GPPMODKI_02456 1.3e-225 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
GPPMODKI_02457 2.2e-174 ybaS 1.1.1.58 S Na -dependent transporter
GPPMODKI_02458 1.4e-109 ybbA S Putative esterase
GPPMODKI_02459 5.2e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPPMODKI_02460 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPPMODKI_02461 2e-172 feuA P Iron-uptake system-binding protein
GPPMODKI_02462 4.4e-310 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
GPPMODKI_02463 1.3e-237 ybbC 3.2.1.52 S protein conserved in bacteria
GPPMODKI_02464 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
GPPMODKI_02465 3.1e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
GPPMODKI_02466 2.8e-236 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPPMODKI_02467 3.1e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPPMODKI_02468 9.1e-86 ybbJ J acetyltransferase
GPPMODKI_02469 1.6e-76 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
GPPMODKI_02475 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
GPPMODKI_02476 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
GPPMODKI_02477 2.3e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPPMODKI_02478 4.4e-224 ybbR S protein conserved in bacteria
GPPMODKI_02479 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPPMODKI_02480 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GPPMODKI_02482 1.1e-306 K SIR2-like domain
GPPMODKI_02483 4.2e-153 V ATPases associated with a variety of cellular activities
GPPMODKI_02484 3.8e-106 S ABC-2 family transporter protein
GPPMODKI_02485 4e-98 ybdN
GPPMODKI_02486 1.1e-132 ybdO S Domain of unknown function (DUF4885)
GPPMODKI_02487 2.8e-162 dkgB S Aldo/keto reductase family
GPPMODKI_02488 5e-93 yxaC M effector of murein hydrolase
GPPMODKI_02489 6.9e-52 S LrgA family
GPPMODKI_02490 2.2e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
GPPMODKI_02492 4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
GPPMODKI_02493 9.4e-95 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GPPMODKI_02494 3.7e-202 T COG4585 Signal transduction histidine kinase
GPPMODKI_02495 1.8e-108 KT LuxR family transcriptional regulator
GPPMODKI_02496 9.2e-167 V COG1131 ABC-type multidrug transport system, ATPase component
GPPMODKI_02497 8.3e-205 V COG0842 ABC-type multidrug transport system, permease component
GPPMODKI_02498 4.3e-198 V ABC-2 family transporter protein
GPPMODKI_02499 2.2e-24
GPPMODKI_02500 4.5e-77 S Domain of unknown function (DUF4879)
GPPMODKI_02501 5.4e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
GPPMODKI_02502 8.9e-106 yqeB
GPPMODKI_02503 9.2e-40 ybyB
GPPMODKI_02504 9.5e-292 ybeC E amino acid
GPPMODKI_02507 6e-42 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GPPMODKI_02508 1.1e-55
GPPMODKI_02509 3.4e-15 S Protein of unknown function (DUF2651)
GPPMODKI_02510 9.7e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GPPMODKI_02511 1.7e-259 glpT G -transporter
GPPMODKI_02512 3.9e-16 S Protein of unknown function (DUF2651)
GPPMODKI_02513 5e-212 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
GPPMODKI_02515 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
GPPMODKI_02516 1.3e-30
GPPMODKI_02517 1.2e-82 K Helix-turn-helix XRE-family like proteins
GPPMODKI_02518 4.3e-200 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
GPPMODKI_02519 8.9e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPPMODKI_02520 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPPMODKI_02521 1.9e-86 ybfM S SNARE associated Golgi protein
GPPMODKI_02522 5.6e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
GPPMODKI_02523 2.3e-41 ybfN
GPPMODKI_02524 5e-192 yceA S Belongs to the UPF0176 family
GPPMODKI_02525 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPPMODKI_02526 1.2e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
GPPMODKI_02527 6.8e-257 mmuP E amino acid
GPPMODKI_02528 2.7e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
GPPMODKI_02529 7.1e-259 agcS E Sodium alanine symporter
GPPMODKI_02530 4.1e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
GPPMODKI_02531 3.1e-213 phoQ 2.7.13.3 T Histidine kinase
GPPMODKI_02532 2.8e-171 glnL T Regulator
GPPMODKI_02533 8.2e-26 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
GPPMODKI_02534 9.3e-36 L Transposase
GPPMODKI_02535 1.8e-156 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPPMODKI_02536 1.5e-112 ydfN C nitroreductase
GPPMODKI_02537 2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
GPPMODKI_02538 4.4e-62 mhqP S DoxX
GPPMODKI_02539 7e-56 traF CO Thioredoxin
GPPMODKI_02540 5.6e-62 ycbP S Protein of unknown function (DUF2512)
GPPMODKI_02541 1.4e-77 sleB 3.5.1.28 M Cell wall
GPPMODKI_02542 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
GPPMODKI_02543 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GPPMODKI_02544 3e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPPMODKI_02545 2.9e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GPPMODKI_02546 5.3e-209 ycbU E Selenocysteine lyase
GPPMODKI_02547 3.1e-238 lmrB EGP the major facilitator superfamily
GPPMODKI_02548 2.7e-100 yxaF K Transcriptional regulator
GPPMODKI_02549 1.4e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GPPMODKI_02550 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPPMODKI_02551 4.1e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
GPPMODKI_02552 8.1e-171 yccK C Aldo keto reductase
GPPMODKI_02553 4e-176 ycdA S Domain of unknown function (DUF5105)
GPPMODKI_02554 2.6e-266 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
GPPMODKI_02555 8.7e-267 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
GPPMODKI_02556 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
GPPMODKI_02557 4.6e-189 S response regulator aspartate phosphatase
GPPMODKI_02558 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
GPPMODKI_02559 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
GPPMODKI_02560 1e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
GPPMODKI_02561 7.2e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GPPMODKI_02562 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GPPMODKI_02563 3.6e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPPMODKI_02564 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
GPPMODKI_02565 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
GPPMODKI_02566 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
GPPMODKI_02567 9.7e-138 terC P Protein of unknown function (DUF475)
GPPMODKI_02568 0.0 yceG S Putative component of 'biosynthetic module'
GPPMODKI_02569 2.3e-193 yceH P Belongs to the TelA family
GPPMODKI_02570 1.2e-214 naiP P Uncharacterised MFS-type transporter YbfB
GPPMODKI_02571 3.9e-229 proV 3.6.3.32 E glycine betaine
GPPMODKI_02572 1.6e-138 opuAB P glycine betaine
GPPMODKI_02573 3.1e-164 opuAC E glycine betaine
GPPMODKI_02574 7.8e-213 amhX S amidohydrolase
GPPMODKI_02575 2.4e-230 ycgA S Membrane
GPPMODKI_02576 1.1e-81 ycgB
GPPMODKI_02577 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
GPPMODKI_02578 1.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GPPMODKI_02579 4e-260 mdr EGP Major facilitator Superfamily
GPPMODKI_02580 1.8e-75 emrR K helix_turn_helix multiple antibiotic resistance protein
GPPMODKI_02581 8e-114 ycgF E Lysine exporter protein LysE YggA
GPPMODKI_02582 1.4e-149 yqcI S YqcI/YcgG family
GPPMODKI_02583 1.1e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
GPPMODKI_02584 7.6e-114 ycgI S Domain of unknown function (DUF1989)
GPPMODKI_02585 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GPPMODKI_02586 2.1e-118 L Molecular Function DNA binding, Biological Process DNA recombination
GPPMODKI_02587 1.1e-40 L transposase activity
GPPMODKI_02589 3.4e-106 tmrB S AAA domain
GPPMODKI_02590 2.8e-148 4.2.1.118 G Xylose isomerase-like TIM barrel
GPPMODKI_02591 1.2e-231 G COG0477 Permeases of the major facilitator superfamily
GPPMODKI_02592 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPPMODKI_02593 1.3e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
GPPMODKI_02594 2.3e-80 ycgL S Predicted nucleotidyltransferase
GPPMODKI_02595 3e-37 ycgL S Predicted nucleotidyltransferase
GPPMODKI_02596 2.3e-170 ycgM E Proline dehydrogenase
GPPMODKI_02597 6.8e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
GPPMODKI_02598 5.8e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPPMODKI_02599 6.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
GPPMODKI_02600 1.3e-187 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
GPPMODKI_02601 3.1e-278 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
GPPMODKI_02602 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
GPPMODKI_02603 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPPMODKI_02604 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GPPMODKI_02605 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
GPPMODKI_02606 2.4e-223 nasA P COG2223 Nitrate nitrite transporter
GPPMODKI_02607 1.2e-227 yciC S GTPases (G3E family)
GPPMODKI_02608 3e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GPPMODKI_02609 1.1e-72 yckC S membrane
GPPMODKI_02610 2.2e-51 S Protein of unknown function (DUF2680)
GPPMODKI_02611 1.6e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GPPMODKI_02612 2.9e-69 nin S Competence protein J (ComJ)
GPPMODKI_02613 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
GPPMODKI_02614 1.4e-93 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
GPPMODKI_02615 2.5e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
GPPMODKI_02616 6.3e-63 hxlR K transcriptional
GPPMODKI_02617 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPPMODKI_02618 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPPMODKI_02619 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
GPPMODKI_02620 2.4e-138 srfAD Q thioesterase
GPPMODKI_02621 2.7e-249 bamJ E Aminotransferase class I and II
GPPMODKI_02622 1.5e-129 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
GPPMODKI_02623 2e-109 yczE S membrane
GPPMODKI_02624 1.5e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GPPMODKI_02625 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
GPPMODKI_02626 3.6e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
GPPMODKI_02627 3.9e-159 bsdA K LysR substrate binding domain
GPPMODKI_02628 2.7e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
GPPMODKI_02629 2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
GPPMODKI_02630 2e-38 bsdD 4.1.1.61 S response to toxic substance
GPPMODKI_02631 9.8e-77 yclD
GPPMODKI_02632 3.2e-270 dtpT E amino acid peptide transporter
GPPMODKI_02633 1.5e-279 yclG M Pectate lyase superfamily protein
GPPMODKI_02635 5.4e-295 gerKA EG Spore germination protein
GPPMODKI_02636 1.8e-234 gerKC S spore germination
GPPMODKI_02637 5.1e-196 gerKB F Spore germination protein
GPPMODKI_02638 4.8e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPPMODKI_02639 2.5e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPPMODKI_02640 7.9e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
GPPMODKI_02641 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
GPPMODKI_02642 7.7e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
GPPMODKI_02643 3.7e-218 yxeP 3.5.1.47 E hydrolase activity
GPPMODKI_02644 7.4e-250 yxeQ S MmgE/PrpD family
GPPMODKI_02645 8.7e-122 yclH P ABC transporter
GPPMODKI_02646 3.5e-226 yclI V ABC transporter (permease) YclI
GPPMODKI_02647 2.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPPMODKI_02648 5.4e-259 T PhoQ Sensor
GPPMODKI_02649 1.6e-80 S aspartate phosphatase
GPPMODKI_02651 1.2e-252 lysC 2.7.2.4 E Belongs to the aspartokinase family
GPPMODKI_02652 6.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPPMODKI_02653 1.1e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPPMODKI_02654 3.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
GPPMODKI_02655 1.2e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
GPPMODKI_02656 6.6e-249 ycnB EGP Major facilitator Superfamily
GPPMODKI_02657 1.2e-152 ycnC K Transcriptional regulator
GPPMODKI_02658 5.2e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
GPPMODKI_02659 2.3e-44 ycnE S Monooxygenase
GPPMODKI_02660 8.8e-53 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
GPPMODKI_02661 2.2e-265 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPPMODKI_02662 2.7e-220 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPPMODKI_02663 5.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPPMODKI_02664 6.1e-149 glcU U Glucose uptake
GPPMODKI_02665 1.9e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPPMODKI_02666 7.8e-98 ycnI S protein conserved in bacteria
GPPMODKI_02667 1.4e-298 ycnJ P protein, homolog of Cu resistance protein CopC
GPPMODKI_02668 1.9e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
GPPMODKI_02669 1.6e-55
GPPMODKI_02670 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
GPPMODKI_02671 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
GPPMODKI_02672 6.4e-207 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
GPPMODKI_02673 1.9e-65 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
GPPMODKI_02675 3.6e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
GPPMODKI_02676 6e-140 ycsF S Belongs to the UPF0271 (lamB) family
GPPMODKI_02677 1.8e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
GPPMODKI_02678 5.7e-149 ycsI S Belongs to the D-glutamate cyclase family
GPPMODKI_02679 3.9e-136 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
GPPMODKI_02680 4.9e-190 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
GPPMODKI_02681 1.5e-130 kipR K Transcriptional regulator
GPPMODKI_02682 4.6e-117 ycsK E anatomical structure formation involved in morphogenesis
GPPMODKI_02684 5.1e-56 yczJ S biosynthesis
GPPMODKI_02685 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
GPPMODKI_02686 1.3e-173 ydhF S Oxidoreductase
GPPMODKI_02687 0.0 mtlR K transcriptional regulator, MtlR
GPPMODKI_02688 1.2e-285 ydaB IQ acyl-CoA ligase
GPPMODKI_02689 3.7e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPPMODKI_02690 1.1e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
GPPMODKI_02691 2.3e-113 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GPPMODKI_02692 3.1e-77 ydaG 1.4.3.5 S general stress protein
GPPMODKI_02693 4.6e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
GPPMODKI_02694 8.7e-47 ydzA EGP Major facilitator Superfamily
GPPMODKI_02695 1.5e-74 lrpC K Transcriptional regulator
GPPMODKI_02696 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPPMODKI_02697 8.6e-193 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
GPPMODKI_02698 1.1e-147 ydaK T Diguanylate cyclase, GGDEF domain
GPPMODKI_02699 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
GPPMODKI_02700 3.2e-231 ydaM M Glycosyl transferase family group 2
GPPMODKI_02701 0.0 ydaN S Bacterial cellulose synthase subunit
GPPMODKI_02702 0.0 ydaO E amino acid
GPPMODKI_02703 6.3e-73 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
GPPMODKI_02704 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
GPPMODKI_02705 5.6e-50 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GPPMODKI_02706 2e-50 V HNH endonuclease
GPPMODKI_02707 6e-89 yokH G SMI1 / KNR4 family
GPPMODKI_02708 3.1e-25
GPPMODKI_02709 5.9e-208 S Histidine kinase
GPPMODKI_02711 5.8e-09
GPPMODKI_02713 1.7e-75
GPPMODKI_02714 8.4e-100
GPPMODKI_02715 2.1e-39
GPPMODKI_02716 3.5e-225 mntH P H( )-stimulated, divalent metal cation uptake system
GPPMODKI_02718 6.5e-34 ydaT
GPPMODKI_02719 4.6e-70 yvaD S Family of unknown function (DUF5360)
GPPMODKI_02720 7e-54 yvaE P Small Multidrug Resistance protein
GPPMODKI_02721 1.8e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
GPPMODKI_02723 9.6e-64 ydbB G Cupin domain
GPPMODKI_02724 1.5e-61 ydbC S Domain of unknown function (DUF4937
GPPMODKI_02725 7.1e-155 ydbD P Catalase
GPPMODKI_02726 6.5e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
GPPMODKI_02727 2.1e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
GPPMODKI_02728 1.1e-118 dctR T COG4565 Response regulator of citrate malate metabolism
GPPMODKI_02729 8.5e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPPMODKI_02730 3.2e-160 ydbI S AI-2E family transporter
GPPMODKI_02731 7.2e-172 ydbJ V ABC transporter, ATP-binding protein
GPPMODKI_02732 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GPPMODKI_02733 2.1e-52 ydbL
GPPMODKI_02734 8.9e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
GPPMODKI_02735 1.5e-10 S Fur-regulated basic protein B
GPPMODKI_02736 5.8e-09 S Fur-regulated basic protein A
GPPMODKI_02737 8.1e-120 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPPMODKI_02738 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GPPMODKI_02739 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GPPMODKI_02740 4.8e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GPPMODKI_02741 2.9e-247 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GPPMODKI_02742 3e-60 ydbS S Bacterial PH domain
GPPMODKI_02743 9.7e-264 ydbT S Membrane
GPPMODKI_02744 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
GPPMODKI_02745 6.8e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GPPMODKI_02746 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
GPPMODKI_02747 6.9e-220 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPPMODKI_02748 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
GPPMODKI_02749 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
GPPMODKI_02750 6.1e-146 rsbR T Positive regulator of sigma-B
GPPMODKI_02751 6.8e-57 rsbS T antagonist
GPPMODKI_02752 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
GPPMODKI_02753 1.7e-187 rsbU 3.1.3.3 KT phosphatase
GPPMODKI_02754 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
GPPMODKI_02755 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
GPPMODKI_02756 1.5e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPPMODKI_02757 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
GPPMODKI_02758 0.0 yhgF K COG2183 Transcriptional accessory protein
GPPMODKI_02759 1.7e-14
GPPMODKI_02760 1.9e-58 ydcK S Belongs to the SprT family
GPPMODKI_02768 2.8e-194 L Belongs to the 'phage' integrase family
GPPMODKI_02769 4.1e-55 immA E IrrE N-terminal-like domain
GPPMODKI_02770 9.3e-44 yvaO K Transcriptional
GPPMODKI_02771 4.1e-13
GPPMODKI_02773 1e-39 S Bacterial protein of unknown function (DUF961)
GPPMODKI_02775 3e-241 ydcQ D Ftsk spoiiie family protein
GPPMODKI_02776 2.5e-168 nicK L Replication initiation factor
GPPMODKI_02781 6.8e-39 yddA
GPPMODKI_02783 3.1e-126 yddB S Conjugative transposon protein TcpC
GPPMODKI_02784 6.8e-24 yddC
GPPMODKI_02785 3.6e-75 yddD S TcpE family
GPPMODKI_02786 0.0 yddE S AAA-like domain
GPPMODKI_02787 5.4e-37 S Domain of unknown function (DUF1874)
GPPMODKI_02788 8.5e-209 yddG S maturation of SSU-rRNA
GPPMODKI_02789 5.9e-159 yddH CBM50 M Lysozyme-like
GPPMODKI_02790 6.1e-56 yddI
GPPMODKI_02791 1.4e-36 S Domain of unknown function with cystatin-like fold (DUF4467)
GPPMODKI_02792 7e-136 P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
GPPMODKI_02793 4.2e-117 fecE 3.6.3.34 HP ABC transporter
GPPMODKI_02794 4.2e-123 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPPMODKI_02795 6.4e-36 K MarR family
GPPMODKI_02796 2.1e-78 EG spore germination
GPPMODKI_02797 3.7e-155 fsr P COG0477 Permeases of the major facilitator superfamily
GPPMODKI_02798 3.8e-61 G Cupin 2, conserved barrel domain protein
GPPMODKI_02800 5.2e-74 S response regulator aspartate phosphatase
GPPMODKI_02803 7.8e-10
GPPMODKI_02804 1.1e-227 proP EGP Transporter
GPPMODKI_02805 9.5e-83 S Domain of unknown function with cystatin-like fold (DUF4467)
GPPMODKI_02806 1.2e-73 maoC I N-terminal half of MaoC dehydratase
GPPMODKI_02807 3.2e-64 yyaQ S YjbR
GPPMODKI_02808 1.3e-73 ywnA K Transcriptional regulator
GPPMODKI_02809 9.9e-112 ywnB S NAD(P)H-binding
GPPMODKI_02810 1.4e-30 cspL K Cold shock
GPPMODKI_02811 5.2e-78 carD K Transcription factor
GPPMODKI_02812 4.6e-39 yrkD S protein conserved in bacteria
GPPMODKI_02813 1.6e-82 yrkE O DsrE/DsrF/DrsH-like family
GPPMODKI_02814 2.1e-58 P Rhodanese Homology Domain
GPPMODKI_02815 4.1e-93 yrkF OP Belongs to the sulfur carrier protein TusA family
GPPMODKI_02816 2.1e-197 yrkH P Rhodanese Homology Domain
GPPMODKI_02817 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
GPPMODKI_02818 2.3e-118 yrkJ S membrane transporter protein
GPPMODKI_02819 1.9e-121 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GPPMODKI_02820 3.8e-99 S Protein of unknown function (DUF2812)
GPPMODKI_02821 4.9e-51 K Transcriptional regulator PadR-like family
GPPMODKI_02822 5.2e-181 S Patatin-like phospholipase
GPPMODKI_02823 6.3e-79 S DinB superfamily
GPPMODKI_02824 5e-117 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
GPPMODKI_02825 7.8e-67 K COG1802 Transcriptional regulators
GPPMODKI_02826 6.6e-39 yabJ 3.5.99.10 J Endoribonuclease L-PSP
GPPMODKI_02827 7.6e-143 sdaC E Serine transporter
GPPMODKI_02828 4.5e-163 E Peptidase dimerisation domain
GPPMODKI_02829 1.7e-125 rhaS5 K helix_turn_helix, arabinose operon control protein
GPPMODKI_02830 5.9e-177 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
GPPMODKI_02831 2.5e-232 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPPMODKI_02832 3.3e-191 ydeG EGP Major facilitator superfamily
GPPMODKI_02833 1.8e-11 3.6.1.55 F Belongs to the Nudix hydrolase family
GPPMODKI_02834 1e-33 3.6.1.55 F Belongs to the Nudix hydrolase family
GPPMODKI_02836 4.6e-268 ygaK C COG0277 FAD FMN-containing dehydrogenases
GPPMODKI_02837 2.2e-78 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPPMODKI_02838 6.6e-165 czcD P COG1230 Co Zn Cd efflux system component
GPPMODKI_02839 5.4e-200 trkA P Oxidoreductase
GPPMODKI_02841 1e-98 yrkC G Cupin domain
GPPMODKI_02842 1.5e-84 ykkA S Protein of unknown function (DUF664)
GPPMODKI_02843 3.3e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
GPPMODKI_02845 7.6e-194 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
GPPMODKI_02846 2e-51 ydeH
GPPMODKI_02847 3.2e-162 S Sodium Bile acid symporter family
GPPMODKI_02848 2.9e-201 adhA 1.1.1.1 C alcohol dehydrogenase
GPPMODKI_02849 8e-67 yraB K helix_turn_helix, mercury resistance
GPPMODKI_02850 5.6e-223 mleN_2 C antiporter
GPPMODKI_02851 1.5e-261 K helix_turn_helix gluconate operon transcriptional repressor
GPPMODKI_02852 1.6e-114 paiB K Transcriptional regulator
GPPMODKI_02854 1.7e-181 ydeR EGP Major facilitator Superfamily
GPPMODKI_02855 1.3e-102 ydeS K Transcriptional regulator
GPPMODKI_02856 1.1e-104 ydeK EG -transporter
GPPMODKI_02857 1.2e-266 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPPMODKI_02858 9.5e-49 yraD M Spore coat protein
GPPMODKI_02859 1.9e-24 yraE
GPPMODKI_02860 2.1e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GPPMODKI_02861 2.9e-63 yraF M Spore coat protein
GPPMODKI_02862 1.2e-36 yraG
GPPMODKI_02863 2.5e-108 ybjJ G Major Facilitator Superfamily
GPPMODKI_02864 1.7e-76 2.7.1.2 GK Transcriptional regulator
GPPMODKI_02865 6.2e-22 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
GPPMODKI_02867 3.6e-214 ydfH 2.7.13.3 T Histidine kinase
GPPMODKI_02868 3.2e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPPMODKI_02869 0.0 ydfJ S drug exporters of the RND superfamily
GPPMODKI_02870 8.8e-133 puuD S Peptidase C26
GPPMODKI_02871 4.7e-299 expZ S ABC transporter
GPPMODKI_02872 2.1e-99 ynaD J Acetyltransferase (GNAT) domain
GPPMODKI_02873 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
GPPMODKI_02874 8.8e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
GPPMODKI_02875 3.9e-210 tcaB EGP Major facilitator Superfamily
GPPMODKI_02876 6.8e-226 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GPPMODKI_02877 1.3e-156 K Helix-turn-helix XRE-family like proteins
GPPMODKI_02878 1.9e-122 ydhB S membrane transporter protein
GPPMODKI_02879 6.9e-83 bltD 2.3.1.57 K FR47-like protein
GPPMODKI_02880 6.9e-150 bltR K helix_turn_helix, mercury resistance
GPPMODKI_02881 2.4e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GPPMODKI_02882 3.5e-114 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
GPPMODKI_02883 2.9e-145 ycgJ_1 Q ubiE/COQ5 methyltransferase family
GPPMODKI_02884 1.4e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
GPPMODKI_02885 4e-119 ydhC K FCD
GPPMODKI_02886 1.7e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GPPMODKI_02889 6.5e-262 pbpE V Beta-lactamase
GPPMODKI_02891 7.2e-98 ydhK M Protein of unknown function (DUF1541)
GPPMODKI_02892 3.4e-195 pbuE EGP Major facilitator Superfamily
GPPMODKI_02893 5.1e-133 ydhQ K UTRA
GPPMODKI_02894 1.4e-116 K FCD
GPPMODKI_02895 4.1e-215 yeaN P COG2807 Cyanate permease
GPPMODKI_02896 1.3e-48 sugE P Small Multidrug Resistance protein
GPPMODKI_02897 1.5e-50 ykkC P Small Multidrug Resistance protein
GPPMODKI_02898 5.3e-104 yvdT K Transcriptional regulator
GPPMODKI_02899 9.3e-297 yveA E amino acid
GPPMODKI_02900 8.7e-164 ydhU P Catalase
GPPMODKI_02901 3.5e-82 yndB S Activator of Hsp90 ATPase homolog 1-like protein
GPPMODKI_02902 1.8e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
GPPMODKI_02903 1.5e-248 iolT EGP Major facilitator Superfamily
GPPMODKI_02906 2e-08
GPPMODKI_02915 2e-08
GPPMODKI_02924 0.0 S peptidoglycan catabolic process
GPPMODKI_02925 2.7e-84 S Phage tail protein
GPPMODKI_02926 1.6e-269 S Pfam Transposase IS66
GPPMODKI_02928 1.6e-90
GPPMODKI_02929 2.2e-263 M Pectate lyase superfamily protein
GPPMODKI_02930 4.8e-79 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GPPMODKI_02932 2.3e-32 S Bacteriophage holin
GPPMODKI_02935 7.4e-211 S aspartate phosphatase
GPPMODKI_02936 1.4e-223 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPPMODKI_02937 1.6e-41 S YolD-like protein
GPPMODKI_02938 4.3e-126 yunB S Sporulation protein YunB (Spo_YunB)
GPPMODKI_02940 5e-87 yokJ S SMI1 / KNR4 family (SUKH-1)
GPPMODKI_02941 4.1e-253 UW nuclease activity
GPPMODKI_02942 7.2e-165 V HNH endonuclease
GPPMODKI_02943 1.5e-92 G SMI1-KNR4 cell-wall
GPPMODKI_02944 4.7e-78 yokF 3.1.31.1 L RNA catabolic process
GPPMODKI_02945 9.3e-97 spoVK O stage V sporulation protein K
GPPMODKI_02946 1.6e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GPPMODKI_02947 6.9e-110 ymaB S MutT family
GPPMODKI_02948 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPPMODKI_02949 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPPMODKI_02950 3.9e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
GPPMODKI_02951 1.8e-20 ymzA
GPPMODKI_02952 9.4e-43
GPPMODKI_02953 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
GPPMODKI_02954 7.4e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPPMODKI_02955 1.4e-47 ymaF S YmaF family
GPPMODKI_02957 6.5e-48 ebrA P Small Multidrug Resistance protein
GPPMODKI_02958 5.2e-54 ebrB P Small Multidrug Resistance protein
GPPMODKI_02959 6e-79 ymaD O redox protein, regulator of disulfide bond formation
GPPMODKI_02960 7.8e-126 ymaC S Replication protein
GPPMODKI_02962 6.8e-256 aprX O Belongs to the peptidase S8 family
GPPMODKI_02963 1.4e-62 ymzB
GPPMODKI_02964 5.1e-117 yoaK S Membrane
GPPMODKI_02965 7e-77 nucB M Deoxyribonuclease NucA/NucB
GPPMODKI_02966 3.4e-230 cypA C Cytochrome P450
GPPMODKI_02967 0.0 pks13 HQ Beta-ketoacyl synthase
GPPMODKI_02968 0.0 dhbF IQ polyketide synthase
GPPMODKI_02969 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
GPPMODKI_02970 0.0 Q Polyketide synthase of type I
GPPMODKI_02971 0.0 rhiB IQ polyketide synthase
GPPMODKI_02972 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
GPPMODKI_02973 5.3e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
GPPMODKI_02974 4.1e-242 pksG 2.3.3.10 I synthase
GPPMODKI_02975 1.9e-34 acpK IQ Phosphopantetheine attachment site
GPPMODKI_02976 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GPPMODKI_02977 2.5e-183 pksD Q Acyl transferase domain
GPPMODKI_02978 2.9e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GPPMODKI_02979 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
GPPMODKI_02982 1.5e-32
GPPMODKI_02983 2.2e-22
GPPMODKI_02984 1.7e-38 L Phage integrase family
GPPMODKI_02985 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPPMODKI_02986 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPPMODKI_02987 1.7e-88 cotE S Spore coat protein
GPPMODKI_02988 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
GPPMODKI_02989 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPPMODKI_02990 3.9e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GPPMODKI_02991 3.6e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
GPPMODKI_02992 1.2e-36 spoVS S Stage V sporulation protein S
GPPMODKI_02993 4.9e-153 ymdB S protein conserved in bacteria
GPPMODKI_02994 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
GPPMODKI_02995 9.2e-180 pbpX V Beta-lactamase
GPPMODKI_02996 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPPMODKI_02997 4.2e-231 cinA 3.5.1.42 S Belongs to the CinA family
GPPMODKI_02998 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPPMODKI_02999 4.6e-123 ymfM S protein conserved in bacteria
GPPMODKI_03000 1e-142 ymfK S Protein of unknown function (DUF3388)
GPPMODKI_03001 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
GPPMODKI_03002 1.5e-127 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
GPPMODKI_03003 7.5e-244 ymfH S zinc protease
GPPMODKI_03004 1.2e-238 ymfF S Peptidase M16
GPPMODKI_03005 0.0 ydgH S drug exporters of the RND superfamily
GPPMODKI_03006 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
GPPMODKI_03007 1.1e-229 ymfD EGP Major facilitator Superfamily
GPPMODKI_03008 1.8e-133 ymfC K Transcriptional regulator
GPPMODKI_03009 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
GPPMODKI_03010 6.3e-31 S YlzJ-like protein
GPPMODKI_03011 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
GPPMODKI_03012 4.4e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPPMODKI_03013 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPPMODKI_03014 4.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
GPPMODKI_03015 1.7e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPPMODKI_03016 1.7e-105 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
GPPMODKI_03017 3.6e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
GPPMODKI_03018 2.6e-42 ymxH S YlmC YmxH family
GPPMODKI_03019 1.5e-233 pepR S Belongs to the peptidase M16 family
GPPMODKI_03020 2e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
GPPMODKI_03021 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GPPMODKI_03022 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPPMODKI_03023 1.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GPPMODKI_03024 7.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPPMODKI_03025 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPPMODKI_03026 3.9e-44 ylxP S protein conserved in bacteria
GPPMODKI_03027 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPPMODKI_03028 1.8e-47 ylxQ J ribosomal protein
GPPMODKI_03029 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
GPPMODKI_03030 5.4e-206 nusA K Participates in both transcription termination and antitermination
GPPMODKI_03031 8.7e-81 rimP S Required for maturation of 30S ribosomal subunits
GPPMODKI_03032 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPPMODKI_03033 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GPPMODKI_03034 5.9e-233 rasP M zinc metalloprotease
GPPMODKI_03035 8.6e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
GPPMODKI_03036 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
GPPMODKI_03037 1.1e-144 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPPMODKI_03038 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GPPMODKI_03039 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GPPMODKI_03040 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPPMODKI_03041 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
GPPMODKI_03042 2e-53 ylxL
GPPMODKI_03043 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPPMODKI_03044 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
GPPMODKI_03045 3.7e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
GPPMODKI_03046 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
GPPMODKI_03047 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
GPPMODKI_03048 5e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
GPPMODKI_03049 4.5e-155 flhG D Belongs to the ParA family
GPPMODKI_03050 8.8e-193 flhF N Flagellar biosynthesis regulator FlhF
GPPMODKI_03051 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPPMODKI_03052 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPPMODKI_03053 7.5e-130 fliR N Flagellar biosynthetic protein FliR
GPPMODKI_03054 2e-37 fliQ N Role in flagellar biosynthesis
GPPMODKI_03055 4.8e-109 fliP N Plays a role in the flagellum-specific transport system
GPPMODKI_03056 5e-111 fliZ N Flagellar biosynthesis protein, FliO
GPPMODKI_03057 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
GPPMODKI_03058 3.4e-187 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPPMODKI_03059 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GPPMODKI_03060 7.8e-57 fliL N Controls the rotational direction of flagella during chemotaxis
GPPMODKI_03061 4e-139 flgG N Flagellar basal body rod
GPPMODKI_03062 5.3e-72 flgD N Flagellar basal body rod modification protein
GPPMODKI_03063 9.4e-205 fliK N Flagellar hook-length control protein
GPPMODKI_03064 4.4e-48 ylxF S MgtE intracellular N domain
GPPMODKI_03065 4.5e-71 fliJ N Flagellar biosynthesis chaperone
GPPMODKI_03066 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
GPPMODKI_03067 6.3e-89 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
GPPMODKI_03068 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GPPMODKI_03069 5.2e-258 fliF N The M ring may be actively involved in energy transduction
GPPMODKI_03070 2.5e-31 fliE N Flagellar hook-basal body
GPPMODKI_03071 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
GPPMODKI_03072 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
GPPMODKI_03073 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GPPMODKI_03074 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPPMODKI_03075 3.3e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPPMODKI_03076 7.2e-172 xerC L tyrosine recombinase XerC
GPPMODKI_03077 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GPPMODKI_03078 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPPMODKI_03079 2.1e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
GPPMODKI_03080 2.3e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GPPMODKI_03081 5.8e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
GPPMODKI_03082 6.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
GPPMODKI_03083 3.6e-302 ylqG
GPPMODKI_03084 4.5e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPPMODKI_03085 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPPMODKI_03086 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GPPMODKI_03087 5.4e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GPPMODKI_03088 5.9e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPPMODKI_03089 1.3e-61 ylqD S YlqD protein
GPPMODKI_03090 1.7e-35 ylqC S Belongs to the UPF0109 family
GPPMODKI_03091 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GPPMODKI_03092 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPPMODKI_03093 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GPPMODKI_03094 3.2e-141 S Phosphotransferase enzyme family
GPPMODKI_03095 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GPPMODKI_03096 0.0 smc D Required for chromosome condensation and partitioning
GPPMODKI_03097 4.4e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GPPMODKI_03098 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPPMODKI_03099 4.6e-129 IQ reductase
GPPMODKI_03100 7e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GPPMODKI_03101 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GPPMODKI_03102 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
GPPMODKI_03103 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPPMODKI_03104 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
GPPMODKI_03105 2.8e-117 sdaAB 4.3.1.17 E L-serine dehydratase
GPPMODKI_03106 1.4e-303 yloV S kinase related to dihydroxyacetone kinase
GPPMODKI_03107 5.5e-59 asp S protein conserved in bacteria
GPPMODKI_03108 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GPPMODKI_03109 5.8e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
GPPMODKI_03110 2.3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GPPMODKI_03111 3.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GPPMODKI_03112 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
GPPMODKI_03113 2.5e-138 stp 3.1.3.16 T phosphatase
GPPMODKI_03114 3.4e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GPPMODKI_03115 2.3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPPMODKI_03116 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPPMODKI_03117 2.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GPPMODKI_03118 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPPMODKI_03119 4.8e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPPMODKI_03120 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GPPMODKI_03121 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GPPMODKI_03122 1.5e-40 ylzA S Belongs to the UPF0296 family
GPPMODKI_03123 1e-154 yloC S stress-induced protein
GPPMODKI_03124 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
GPPMODKI_03125 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
GPPMODKI_03126 4.1e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
GPPMODKI_03127 5.8e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
GPPMODKI_03128 5.3e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
GPPMODKI_03129 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
GPPMODKI_03130 3.8e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
GPPMODKI_03131 1.8e-179 cysP P phosphate transporter
GPPMODKI_03132 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
GPPMODKI_03134 7.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPPMODKI_03135 1.4e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GPPMODKI_03136 6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GPPMODKI_03137 1.9e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GPPMODKI_03138 0.0 carB 6.3.5.5 F Belongs to the CarB family
GPPMODKI_03139 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GPPMODKI_03140 6.6e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GPPMODKI_03141 2e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GPPMODKI_03142 8e-233 pyrP F Xanthine uracil
GPPMODKI_03143 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GPPMODKI_03144 2.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPPMODKI_03145 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPPMODKI_03146 3.8e-63 dksA T COG1734 DnaK suppressor protein
GPPMODKI_03147 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPPMODKI_03148 8.9e-68 divIVA D Cell division initiation protein
GPPMODKI_03149 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
GPPMODKI_03150 5.2e-41 yggT S membrane
GPPMODKI_03151 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GPPMODKI_03152 1.5e-121 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPPMODKI_03153 5.7e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
GPPMODKI_03154 2.2e-38 ylmC S sporulation protein
GPPMODKI_03155 7.2e-255 argE 3.5.1.16 E Acetylornithine deacetylase
GPPMODKI_03156 4.5e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
GPPMODKI_03157 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPPMODKI_03158 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPPMODKI_03159 1.7e-160 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
GPPMODKI_03160 0.0 bpr O COG1404 Subtilisin-like serine proteases
GPPMODKI_03161 5.8e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPPMODKI_03162 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GPPMODKI_03163 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GPPMODKI_03164 3.7e-168 murB 1.3.1.98 M cell wall formation
GPPMODKI_03165 3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPPMODKI_03166 2.2e-185 spoVE D Belongs to the SEDS family
GPPMODKI_03167 5.9e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPPMODKI_03168 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPPMODKI_03169 7.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPPMODKI_03170 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
GPPMODKI_03171 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
GPPMODKI_03172 1.1e-51 ftsL D Essential cell division protein
GPPMODKI_03173 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GPPMODKI_03174 1.2e-77 mraZ K Belongs to the MraZ family
GPPMODKI_03175 2.8e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GPPMODKI_03176 6.7e-162 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPPMODKI_03177 3.1e-89 ylbP K n-acetyltransferase
GPPMODKI_03178 7.6e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
GPPMODKI_03179 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GPPMODKI_03180 3.3e-89 yceD S metal-binding, possibly nucleic acid-binding protein
GPPMODKI_03181 2.3e-229 ylbM S Belongs to the UPF0348 family
GPPMODKI_03182 5.5e-189 ylbL T Belongs to the peptidase S16 family
GPPMODKI_03183 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
GPPMODKI_03184 1.7e-216 ylbJ S Sporulation integral membrane protein YlbJ
GPPMODKI_03185 7.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPPMODKI_03186 8.5e-90 rsmD 2.1.1.171 L Methyltransferase
GPPMODKI_03188 7.2e-43 ylbG S UPF0298 protein
GPPMODKI_03189 1.2e-71 ylbF S Belongs to the UPF0342 family
GPPMODKI_03190 8.8e-37 ylbE S YlbE-like protein
GPPMODKI_03191 1.9e-55 ylbD S Putative coat protein
GPPMODKI_03192 1.5e-197 ylbC S protein with SCP PR1 domains
GPPMODKI_03193 6.3e-73 ylbB T COG0517 FOG CBS domain
GPPMODKI_03194 8.5e-60 ylbA S YugN-like family
GPPMODKI_03195 2.8e-165 ctaG S cytochrome c oxidase
GPPMODKI_03196 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
GPPMODKI_03197 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
GPPMODKI_03198 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPPMODKI_03199 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
GPPMODKI_03200 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GPPMODKI_03201 1.9e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
GPPMODKI_03202 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GPPMODKI_03203 1.4e-212 ftsW D Belongs to the SEDS family
GPPMODKI_03204 8.7e-44 ylaN S Belongs to the UPF0358 family
GPPMODKI_03205 4e-119 glsA 3.5.1.2 E Belongs to the glutaminase family
GPPMODKI_03206 1.3e-73 L Recombinase zinc beta ribbon domain
GPPMODKI_03210 9.1e-12 kilA K SOS response
GPPMODKI_03215 1.3e-51
GPPMODKI_03216 2e-131 KL Phage plasmid primase P4 family
GPPMODKI_03217 1.6e-190
GPPMODKI_03220 8.7e-46
GPPMODKI_03221 8.4e-12
GPPMODKI_03223 1.9e-54
GPPMODKI_03224 1.2e-49
GPPMODKI_03230 3.7e-48 L Phage integrase, N-terminal SAM-like domain
GPPMODKI_03231 7.3e-33 L GIY-YIG catalytic domain
GPPMODKI_03234 5.1e-116 S peptidoglycan catabolic process
GPPMODKI_03235 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GPPMODKI_03236 0.0 S Pfam Transposase IS66
GPPMODKI_03237 1.6e-06
GPPMODKI_03238 1.9e-22
GPPMODKI_03239 2.1e-160 S aspartate phosphatase
GPPMODKI_03241 5.1e-28 S Protein of unknown function (DUF1433)
GPPMODKI_03242 2.2e-183 I Pfam Lipase (class 3)
GPPMODKI_03243 1.4e-23
GPPMODKI_03244 9.8e-44
GPPMODKI_03246 2.5e-23 K Helix-turn-helix domain
GPPMODKI_03248 3.4e-09 K Transcriptional regulator
GPPMODKI_03253 4.3e-07
GPPMODKI_03259 5.2e-47 glsA 3.5.1.2 E Belongs to the glutaminase family
GPPMODKI_03260 6.5e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GPPMODKI_03261 1.2e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
GPPMODKI_03262 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GPPMODKI_03263 1e-33 ylaI S protein conserved in bacteria
GPPMODKI_03264 1.3e-48 ylaH S YlaH-like protein
GPPMODKI_03265 0.0 typA T GTP-binding protein TypA
GPPMODKI_03266 6.7e-24 S Family of unknown function (DUF5325)
GPPMODKI_03267 1.4e-38 ylaE
GPPMODKI_03268 6.3e-13 sigC S Putative zinc-finger
GPPMODKI_03269 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
GPPMODKI_03270 5.2e-83 ykzC S Acetyltransferase (GNAT) family
GPPMODKI_03271 4.2e-152 suhB 3.1.3.25 G Inositol monophosphatase
GPPMODKI_03272 9.7e-25 ykzI
GPPMODKI_03273 4.9e-119 yktB S Belongs to the UPF0637 family
GPPMODKI_03274 1.6e-42 yktA S Belongs to the UPF0223 family
GPPMODKI_03275 3.1e-278 speA 4.1.1.19 E Arginine
GPPMODKI_03276 1.4e-139 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
GPPMODKI_03277 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
GPPMODKI_03278 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GPPMODKI_03279 2.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPPMODKI_03280 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GPPMODKI_03281 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GPPMODKI_03282 2.7e-210 V Beta-lactamase
GPPMODKI_03283 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
GPPMODKI_03284 0.0 Q Polyketide synthase of type I
GPPMODKI_03285 0.0 Q Polyketide synthase of type I
GPPMODKI_03286 0.0 Q Polyketide synthase of type I
GPPMODKI_03287 0.0 Q Polyketide synthase of type I
GPPMODKI_03288 0.0 Q polyketide synthase
GPPMODKI_03289 0.0 Q Polyketide synthase of type I
GPPMODKI_03290 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GPPMODKI_03291 2.9e-103 recN L Putative cell-wall binding lipoprotein
GPPMODKI_03293 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GPPMODKI_03294 1.1e-146 ykrA S hydrolases of the HAD superfamily
GPPMODKI_03295 8.2e-31 ykzG S Belongs to the UPF0356 family
GPPMODKI_03296 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPPMODKI_03297 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GPPMODKI_03298 4.5e-115 ktrA P COG0569 K transport systems, NAD-binding component
GPPMODKI_03299 2.6e-149 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
GPPMODKI_03300 6.3e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
GPPMODKI_03301 1.8e-44 abrB K of stationary sporulation gene expression
GPPMODKI_03302 7.7e-183 mreB D Rod-share determining protein MreBH
GPPMODKI_03303 5.5e-12 S Uncharacterized protein YkpC
GPPMODKI_03304 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
GPPMODKI_03305 1.1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPPMODKI_03306 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GPPMODKI_03307 1.3e-36 ykoA
GPPMODKI_03308 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
GPPMODKI_03309 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
GPPMODKI_03310 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
GPPMODKI_03311 4.6e-132 fruR K Transcriptional regulator
GPPMODKI_03312 3.9e-210 yknZ V ABC transporter (permease)
GPPMODKI_03313 6.1e-123 macB V ABC transporter, ATP-binding protein
GPPMODKI_03314 1.4e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPPMODKI_03315 9.5e-108 yknW S Yip1 domain
GPPMODKI_03316 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPPMODKI_03317 3.5e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
GPPMODKI_03318 3.8e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
GPPMODKI_03319 2.9e-243 moeA 2.10.1.1 H molybdopterin
GPPMODKI_03320 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GPPMODKI_03321 8.2e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
GPPMODKI_03322 2.5e-162 yknT
GPPMODKI_03323 1.7e-97 rok K Repressor of ComK
GPPMODKI_03324 2.3e-78 ykuV CO thiol-disulfide
GPPMODKI_03325 1.9e-139 ykuT M Mechanosensitive ion channel
GPPMODKI_03326 4.8e-38 ykuS S Belongs to the UPF0180 family
GPPMODKI_03327 1.5e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GPPMODKI_03328 1.3e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GPPMODKI_03329 3e-78 fld C Flavodoxin
GPPMODKI_03330 1.6e-171 ykuO
GPPMODKI_03331 6.1e-90 fld C Flavodoxin
GPPMODKI_03332 4.6e-168 ccpC K Transcriptional regulator
GPPMODKI_03333 1e-75 ykuL S CBS domain
GPPMODKI_03334 2.1e-25 ykzF S Antirepressor AbbA
GPPMODKI_03335 1.7e-93 ykuK S Ribonuclease H-like
GPPMODKI_03336 3.9e-37 ykuJ S protein conserved in bacteria
GPPMODKI_03337 1.7e-232 ykuI T Diguanylate phosphodiesterase
GPPMODKI_03339 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPPMODKI_03340 9.2e-153 ykuE S Metallophosphoesterase
GPPMODKI_03341 1.2e-88 ykuD S protein conserved in bacteria
GPPMODKI_03342 1.1e-239 ykuC EGP Major facilitator Superfamily
GPPMODKI_03343 1.2e-82 ykyB S YkyB-like protein
GPPMODKI_03344 2.6e-166 cheV 2.7.13.3 T Chemotaxis protein CheV
GPPMODKI_03345 2.3e-09
GPPMODKI_03346 3.9e-215 patA 2.6.1.1 E Aminotransferase
GPPMODKI_03347 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
GPPMODKI_03348 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
GPPMODKI_03349 7.4e-93 ykwD J protein with SCP PR1 domains
GPPMODKI_03350 5.6e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
GPPMODKI_03351 1.8e-265 mcpC NT chemotaxis protein
GPPMODKI_03352 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
GPPMODKI_03353 6.1e-38 splA S Transcriptional regulator
GPPMODKI_03354 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPPMODKI_03355 2.1e-39 ptsH G phosphocarrier protein HPr
GPPMODKI_03356 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPPMODKI_03357 5.1e-156 glcT K antiterminator
GPPMODKI_03358 1.7e-176 ykvZ 5.1.1.1 K Transcriptional regulator
GPPMODKI_03360 1.8e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
GPPMODKI_03361 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
GPPMODKI_03362 2.9e-87 stoA CO thiol-disulfide
GPPMODKI_03363 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPPMODKI_03364 2.4e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
GPPMODKI_03365 1.3e-27
GPPMODKI_03366 7.8e-25 ykvS S protein conserved in bacteria
GPPMODKI_03367 1.3e-44 ykvR S Protein of unknown function (DUF3219)
GPPMODKI_03369 9e-162 G Glycosyl hydrolases family 18
GPPMODKI_03370 3.9e-34 3.5.1.104 M LysM domain
GPPMODKI_03371 7.8e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
GPPMODKI_03372 1.1e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPPMODKI_03373 7.7e-132 IQ Enoyl-(Acyl carrier protein) reductase
GPPMODKI_03374 4.9e-60 ykvN K Transcriptional regulator
GPPMODKI_03375 8.5e-95 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPPMODKI_03376 2.2e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GPPMODKI_03377 1.7e-78 queD 4.1.2.50, 4.2.3.12 H synthase
GPPMODKI_03378 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPPMODKI_03379 4.5e-184
GPPMODKI_03380 2.5e-181 ykvI S membrane
GPPMODKI_03381 0.0 clpE O Belongs to the ClpA ClpB family
GPPMODKI_03382 1.1e-136 motA N flagellar motor
GPPMODKI_03383 4.6e-127 motB N Flagellar motor protein
GPPMODKI_03384 5.5e-77 ykvE K transcriptional
GPPMODKI_03385 2.1e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
GPPMODKI_03386 3.4e-10 S Spo0E like sporulation regulatory protein
GPPMODKI_03387 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GPPMODKI_03388 4.7e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
GPPMODKI_03389 1.9e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GPPMODKI_03390 6.1e-227 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
GPPMODKI_03391 4.9e-229 mtnE 2.6.1.83 E Aminotransferase
GPPMODKI_03392 2.3e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GPPMODKI_03393 1e-226 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GPPMODKI_03394 1.8e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GPPMODKI_03396 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPPMODKI_03397 0.0 kinE 2.7.13.3 T Histidine kinase
GPPMODKI_03398 8e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
GPPMODKI_03399 8.7e-23 ykzE
GPPMODKI_03400 4.7e-112 ydfR S Protein of unknown function (DUF421)
GPPMODKI_03401 1.4e-240 ktrB P COG0168 Trk-type K transport systems, membrane components
GPPMODKI_03402 4.1e-156 htpX O Belongs to the peptidase M48B family
GPPMODKI_03403 2.3e-125 ykrK S Domain of unknown function (DUF1836)
GPPMODKI_03404 2.5e-26 sspD S small acid-soluble spore protein
GPPMODKI_03405 9e-119 rsgI S Anti-sigma factor N-terminus
GPPMODKI_03406 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPPMODKI_03407 2.1e-135 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
GPPMODKI_03408 1.7e-99 ykoX S membrane-associated protein
GPPMODKI_03409 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GPPMODKI_03410 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
GPPMODKI_03411 2.2e-99 ykoP G polysaccharide deacetylase
GPPMODKI_03412 1.1e-80 ykoM K transcriptional
GPPMODKI_03413 3.1e-26 ykoL
GPPMODKI_03414 1.9e-16
GPPMODKI_03415 1.6e-52 tnrA K transcriptional
GPPMODKI_03416 5e-238 mgtE P Acts as a magnesium transporter
GPPMODKI_03418 1e-245 ydhD M Glycosyl hydrolase
GPPMODKI_03419 5.9e-98 ykoE S ABC-type cobalt transport system, permease component
GPPMODKI_03420 4.4e-305 P ABC transporter, ATP-binding protein
GPPMODKI_03421 1.2e-132 ykoC P Cobalt transport protein
GPPMODKI_03422 5.6e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GPPMODKI_03423 3.8e-176 isp O Belongs to the peptidase S8 family
GPPMODKI_03424 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPPMODKI_03425 9.6e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
GPPMODKI_03426 5.5e-217 hcaT 1.5.1.2 EGP Major facilitator Superfamily
GPPMODKI_03427 6.2e-114 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
GPPMODKI_03428 1.9e-214 M Glycosyl transferase family 2
GPPMODKI_03430 1.1e-56 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPPMODKI_03431 4.2e-71 ohrB O Organic hydroperoxide resistance protein
GPPMODKI_03432 1.5e-86 ohrR K COG1846 Transcriptional regulators
GPPMODKI_03433 1.3e-70 ohrA O Organic hydroperoxide resistance protein
GPPMODKI_03434 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPPMODKI_03435 1.6e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPPMODKI_03436 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
GPPMODKI_03437 3.4e-49 ykkD P Multidrug resistance protein
GPPMODKI_03438 1.6e-52 ykkC P Multidrug resistance protein
GPPMODKI_03439 7.4e-100 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GPPMODKI_03440 1.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
GPPMODKI_03441 4.2e-158 ykgA E Amidinotransferase
GPPMODKI_03442 1.5e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
GPPMODKI_03443 9.6e-183 ykfD E Belongs to the ABC transporter superfamily
GPPMODKI_03444 5e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GPPMODKI_03445 2.6e-197 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
GPPMODKI_03446 1.6e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
GPPMODKI_03447 0.0 dppE E ABC transporter substrate-binding protein
GPPMODKI_03448 7.7e-191 dppD P Belongs to the ABC transporter superfamily
GPPMODKI_03449 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPPMODKI_03450 2.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPPMODKI_03451 6.5e-156 dppA E D-aminopeptidase
GPPMODKI_03453 2.7e-280 yubD P Major Facilitator Superfamily
GPPMODKI_03454 1.8e-203 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPPMODKI_03456 1.2e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GPPMODKI_03457 1.5e-308 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPPMODKI_03458 4.1e-178 mhqA E COG0346 Lactoylglutathione lyase and related lyases
GPPMODKI_03459 5.2e-243 steT E amino acid
GPPMODKI_03460 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
GPPMODKI_03461 5.8e-175 pit P phosphate transporter
GPPMODKI_03462 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
GPPMODKI_03463 8.7e-23 spoIISB S Stage II sporulation protein SB
GPPMODKI_03464 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GPPMODKI_03465 3e-38 xhlB S SPP1 phage holin
GPPMODKI_03466 8.7e-38 xhlA S Haemolysin XhlA
GPPMODKI_03467 3.6e-137 xepA
GPPMODKI_03468 6.5e-30 xkdX
GPPMODKI_03470 1e-31
GPPMODKI_03471 2.7e-43 xkdQ 3.2.1.96 G NLP P60 protein
GPPMODKI_03472 4.9e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GPPMODKI_03473 2e-10 yqaO S Phage-like element PBSX protein XtrA
GPPMODKI_03476 8.5e-153 xkdC L Bacterial dnaA protein
GPPMODKI_03478 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
GPPMODKI_03479 2.5e-109 xkdA E IrrE N-terminal-like domain
GPPMODKI_03480 3.6e-111 yjqB S phage-related replication protein
GPPMODKI_03481 4.7e-61 yjqA S Bacterial PH domain
GPPMODKI_03482 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GPPMODKI_03484 4.9e-215 S response regulator aspartate phosphatase
GPPMODKI_03485 3.1e-78 yjoA S DinB family
GPPMODKI_03486 3.9e-131 MA20_18170 S membrane transporter protein
GPPMODKI_03487 1.7e-276 uxaA 4.2.1.7, 4.4.1.24 G Altronate
GPPMODKI_03488 7.3e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
GPPMODKI_03489 3.4e-183 exuR K transcriptional
GPPMODKI_03490 3.9e-254 yjmB G symporter YjmB
GPPMODKI_03491 3.3e-277 uxaC 5.3.1.12 G glucuronate isomerase
GPPMODKI_03492 1.3e-218 yjlD 1.6.99.3 C NADH dehydrogenase
GPPMODKI_03493 7e-66 yjlC S Protein of unknown function (DUF1641)
GPPMODKI_03494 4.9e-90 yjlB S Cupin domain
GPPMODKI_03495 7.9e-177 yjlA EG Putative multidrug resistance efflux transporter
GPPMODKI_03496 2.2e-131 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
GPPMODKI_03497 1.2e-107 ybbM S transport system, permease component
GPPMODKI_03498 2.1e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
GPPMODKI_03499 6.8e-29
GPPMODKI_03500 3.7e-221 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GPPMODKI_03501 2.2e-224 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
GPPMODKI_03502 2.2e-91 yjgD S Protein of unknown function (DUF1641)
GPPMODKI_03503 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
GPPMODKI_03504 5.9e-100 yjgB S Domain of unknown function (DUF4309)
GPPMODKI_03505 1.2e-65 T PhoQ Sensor
GPPMODKI_03506 1.1e-20 yjfB S Putative motility protein
GPPMODKI_03508 8.1e-106 yhiD S MgtC SapB transporter
GPPMODKI_03509 3.8e-51 K helix_turn_helix multiple antibiotic resistance protein
GPPMODKI_03510 2.6e-34
GPPMODKI_03511 1.7e-125 5.4.2.6 S Haloacid dehalogenase-like hydrolase
GPPMODKI_03512 5.7e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
GPPMODKI_03513 3.6e-284 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
GPPMODKI_03514 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
GPPMODKI_03515 1.2e-310 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPPMODKI_03516 1.3e-215 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPPMODKI_03517 1.6e-185 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GPPMODKI_03518 3.4e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GPPMODKI_03519 1.6e-221 ganA 3.2.1.89 G arabinogalactan
GPPMODKI_03520 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
GPPMODKI_03521 1.6e-250 yfjF EGP Belongs to the major facilitator superfamily
GPPMODKI_03522 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
GPPMODKI_03523 1.9e-148 bla 3.5.2.6 V beta-lactamase
GPPMODKI_03524 8.5e-58 E Glyoxalase-like domain
GPPMODKI_03527 8.7e-73 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
GPPMODKI_03528 3.6e-49 FG Scavenger mRNA decapping enzyme C-term binding
GPPMODKI_03529 3.5e-84 yqjL S Alpha beta hydrolase
GPPMODKI_03531 1.7e-252 yobL S Bacterial EndoU nuclease
GPPMODKI_03532 6.7e-31
GPPMODKI_03533 1.2e-281 V COG1002 Type II restriction enzyme, methylase subunits
GPPMODKI_03534 2.2e-07 3.1.3.16 S Protein of unknown function (DUF1643)
GPPMODKI_03539 3.9e-10 K Cro/C1-type HTH DNA-binding domain
GPPMODKI_03541 9.5e-15 K Helix-turn-helix domain
GPPMODKI_03543 8.9e-28 M D-alanyl-D-alanine carboxypeptidase
GPPMODKI_03544 1.1e-09
GPPMODKI_03545 3.6e-32 S Bacteriophage HK97-gp10, putative tail-component
GPPMODKI_03546 1e-19 S Phage head-tail joining protein
GPPMODKI_03547 4.1e-20 S Phage gp6-like head-tail connector protein
GPPMODKI_03548 8.3e-104 S capsid protein
GPPMODKI_03549 6.7e-54 pi136 S Caudovirus prohead serine protease
GPPMODKI_03550 7e-146 S portal protein
GPPMODKI_03552 3.3e-122 terL S Terminase
GPPMODKI_03553 1.1e-51 terS L Terminase, small subunit
GPPMODKI_03555 1.3e-13 S HNH endonuclease
GPPMODKI_03562 2e-55 K BRO family, N-terminal domain
GPPMODKI_03563 6.1e-203
GPPMODKI_03564 3.6e-45
GPPMODKI_03568 3.2e-61
GPPMODKI_03569 7.1e-61 kilA S Phage regulatory protein Rha (Phage_pRha)
GPPMODKI_03572 4.2e-81 L Belongs to the 'phage' integrase family
GPPMODKI_03574 2.6e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GPPMODKI_03575 1.2e-213 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GPPMODKI_03576 7.2e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
GPPMODKI_03577 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
GPPMODKI_03578 4.7e-73 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPPMODKI_03579 9.4e-36 K SpoVT / AbrB like domain
GPPMODKI_03580 2.9e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
GPPMODKI_03581 1.2e-124 S ABC-2 type transporter
GPPMODKI_03582 6.3e-142 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
GPPMODKI_03583 6.7e-35
GPPMODKI_03584 0.0 yjcD 3.6.4.12 L DNA helicase
GPPMODKI_03585 3.8e-38 spoVIF S Stage VI sporulation protein F
GPPMODKI_03589 7.3e-56 yjcA S Protein of unknown function (DUF1360)
GPPMODKI_03590 1.4e-39 cotV S Spore Coat Protein X and V domain
GPPMODKI_03591 1e-21 cotW
GPPMODKI_03592 1.5e-70 cotX S Spore Coat Protein X and V domain
GPPMODKI_03593 8.1e-90 cotY S Spore coat protein Z
GPPMODKI_03594 2.6e-79 cotZ S Spore coat protein
GPPMODKI_03595 3e-89 yjbX S Spore coat protein
GPPMODKI_03596 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
GPPMODKI_03597 7.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPPMODKI_03598 5.4e-189 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GPPMODKI_03599 1.3e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
GPPMODKI_03600 6.7e-30 thiS H Thiamine biosynthesis
GPPMODKI_03601 8.6e-212 thiO 1.4.3.19 E Glycine oxidase
GPPMODKI_03602 1e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
GPPMODKI_03603 7.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GPPMODKI_03604 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GPPMODKI_03605 4.7e-145 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
GPPMODKI_03607 8.8e-29 L COG2963 Transposase and inactivated derivatives
GPPMODKI_03608 6.5e-137 L Molecular Function DNA binding, Biological Process DNA recombination
GPPMODKI_03609 7e-164 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPPMODKI_03610 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPPMODKI_03611 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
GPPMODKI_03612 1.6e-61 yjbL S Belongs to the UPF0738 family
GPPMODKI_03613 3.5e-100 yjbK S protein conserved in bacteria
GPPMODKI_03614 4.9e-117 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GPPMODKI_03615 1.5e-70 yjbI S Bacterial-like globin
GPPMODKI_03616 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
GPPMODKI_03617 5.8e-19
GPPMODKI_03618 0.0 pepF E oligoendopeptidase F
GPPMODKI_03619 1.2e-216 yjbF S Competence protein
GPPMODKI_03620 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GPPMODKI_03621 5.6e-110 yjbE P Integral membrane protein TerC family
GPPMODKI_03622 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GPPMODKI_03623 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPPMODKI_03624 1.3e-229 S Putative glycosyl hydrolase domain
GPPMODKI_03625 1.1e-169 oppF E Belongs to the ABC transporter superfamily
GPPMODKI_03626 2.7e-202 oppD P Belongs to the ABC transporter superfamily
GPPMODKI_03627 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPPMODKI_03628 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPPMODKI_03629 0.0 oppA E ABC transporter substrate-binding protein
GPPMODKI_03630 8.8e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
GPPMODKI_03631 5.5e-146 yjbA S Belongs to the UPF0736 family
GPPMODKI_03632 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPPMODKI_03633 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPPMODKI_03634 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
GPPMODKI_03635 8.5e-187 appF E Belongs to the ABC transporter superfamily
GPPMODKI_03636 1.7e-182 appD P Belongs to the ABC transporter superfamily
GPPMODKI_03637 1.8e-147 yjaZ O Zn-dependent protease
GPPMODKI_03638 2.9e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GPPMODKI_03639 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPPMODKI_03640 5.9e-32 yjzB
GPPMODKI_03641 1.1e-26 comZ S ComZ
GPPMODKI_03642 1.9e-166 med S Transcriptional activator protein med
GPPMODKI_03643 1.4e-104 yjaV
GPPMODKI_03644 9.9e-140 yjaU I carboxylic ester hydrolase activity
GPPMODKI_03645 1.5e-23 yjzD S Protein of unknown function (DUF2929)
GPPMODKI_03646 1.2e-27 yjzC S YjzC-like protein
GPPMODKI_03647 2.1e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPPMODKI_03648 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
GPPMODKI_03649 1.8e-203 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GPPMODKI_03650 1.9e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
GPPMODKI_03651 4.9e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
GPPMODKI_03652 1.6e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GPPMODKI_03653 6.8e-195 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPPMODKI_03654 1.2e-89 norB G Major Facilitator Superfamily
GPPMODKI_03655 3.5e-272 yitY C D-arabinono-1,4-lactone oxidase
GPPMODKI_03656 2.4e-80 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
GPPMODKI_03657 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
GPPMODKI_03658 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
GPPMODKI_03659 3.3e-152 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
GPPMODKI_03660 3.5e-07
GPPMODKI_03661 4.4e-26 S Protein of unknown function (DUF3813)
GPPMODKI_03662 2.9e-81 ipi S Intracellular proteinase inhibitor
GPPMODKI_03663 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
GPPMODKI_03664 3.2e-158 yitS S protein conserved in bacteria
GPPMODKI_03666 5.8e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
GPPMODKI_03667 1.7e-232 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
GPPMODKI_03668 4.1e-173 yufN S ABC transporter substrate-binding protein PnrA-like
GPPMODKI_03669 5.3e-161 cvfB S protein conserved in bacteria
GPPMODKI_03670 5.6e-54 yajQ S Belongs to the UPF0234 family
GPPMODKI_03671 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
GPPMODKI_03672 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
GPPMODKI_03673 3.2e-70 mcbG S Pentapeptide repeats (9 copies)
GPPMODKI_03674 1e-84 yisT S DinB family
GPPMODKI_03675 3.6e-156 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
GPPMODKI_03676 2.4e-144 purR K helix_turn _helix lactose operon repressor
GPPMODKI_03677 5.9e-160 yisR K Transcriptional regulator
GPPMODKI_03678 1.5e-245 yisQ V Mate efflux family protein
GPPMODKI_03679 2.1e-129 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
GPPMODKI_03680 0.0 asnO 6.3.5.4 E Asparagine synthase
GPPMODKI_03681 6.5e-96 yisN S Protein of unknown function (DUF2777)
GPPMODKI_03682 3.2e-59 yisL S UPF0344 protein
GPPMODKI_03683 1.2e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
GPPMODKI_03684 5e-07 yisI S Spo0E like sporulation regulatory protein
GPPMODKI_03685 8.4e-34 gerPA S Spore germination protein
GPPMODKI_03686 6.2e-35 gerPB S cell differentiation
GPPMODKI_03687 9.1e-62 gerPC S Spore germination protein
GPPMODKI_03688 1.2e-22 gerPD S Spore germination protein
GPPMODKI_03689 1.2e-62 gerPE S Spore germination protein GerPE
GPPMODKI_03690 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
GPPMODKI_03691 5.5e-49 yisB V COG1403 Restriction endonuclease
GPPMODKI_03692 0.0 sbcC L COG0419 ATPase involved in DNA repair
GPPMODKI_03693 3.9e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GPPMODKI_03694 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GPPMODKI_03695 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
GPPMODKI_03696 3.3e-124 ydfS S Protein of unknown function (DUF421)
GPPMODKI_03697 9.7e-94 yhjR S Rubrerythrin
GPPMODKI_03698 1.1e-107 K QacR-like protein, C-terminal region
GPPMODKI_03699 2.1e-203 blt EGP Major facilitator Superfamily
GPPMODKI_03700 4e-188 abrB S membrane
GPPMODKI_03701 5.8e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
GPPMODKI_03702 1.7e-276 yhjG CH FAD binding domain
GPPMODKI_03703 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
GPPMODKI_03704 3.5e-109 yhjE S SNARE associated Golgi protein
GPPMODKI_03705 1.7e-60 yhjD
GPPMODKI_03706 1.4e-27 yhjC S Protein of unknown function (DUF3311)
GPPMODKI_03707 2.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPPMODKI_03708 3.3e-47 S Belongs to the UPF0145 family
GPPMODKI_03709 1.6e-42 yhjA S Excalibur calcium-binding domain
GPPMODKI_03710 1.9e-127 yrpD S Domain of unknown function, YrpD
GPPMODKI_03711 5.4e-167 els S Acetyltransferase, GNAT family
GPPMODKI_03712 1.4e-65 frataxin S Domain of unknown function (DU1801)
GPPMODKI_03713 3.9e-68 frataxin S Domain of unknown function (DU1801)
GPPMODKI_03714 1.9e-109 comK K Competence transcription factor
GPPMODKI_03715 1.8e-31 yhzC S IDEAL
GPPMODKI_03716 8.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPPMODKI_03717 4.8e-298 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
GPPMODKI_03718 1.5e-199 hemAT NT chemotaxis protein
GPPMODKI_03719 3.5e-89 bioY S BioY family
GPPMODKI_03720 1.6e-274 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
GPPMODKI_03721 8.7e-201 vraB 2.3.1.9 I Belongs to the thiolase family
GPPMODKI_03722 2.6e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
GPPMODKI_03723 5.1e-151 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
GPPMODKI_03724 3.4e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
GPPMODKI_03725 4.8e-235 yhfN 3.4.24.84 O Peptidase M48
GPPMODKI_03726 1.9e-65 yhfM
GPPMODKI_03727 7e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
GPPMODKI_03728 1.7e-111 yhfK GM NmrA-like family
GPPMODKI_03729 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
GPPMODKI_03730 8.4e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
GPPMODKI_03731 7.9e-11 yhfH S YhfH-like protein
GPPMODKI_03732 3.4e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPPMODKI_03733 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
GPPMODKI_03735 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPPMODKI_03736 2.1e-276 yhgE S YhgE Pip N-terminal domain protein
GPPMODKI_03737 3.2e-101 yhgD K Transcriptional regulator
GPPMODKI_03738 7.8e-274 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GPPMODKI_03739 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
GPPMODKI_03740 3.3e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GPPMODKI_03741 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GPPMODKI_03742 1.9e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
GPPMODKI_03743 5.3e-243 yhfA C membrane
GPPMODKI_03744 6.1e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GPPMODKI_03745 2.1e-123 ecsC S EcsC protein family
GPPMODKI_03746 6.5e-221 ecsB U ABC transporter
GPPMODKI_03747 1.1e-135 ecsA V transporter (ATP-binding protein)
GPPMODKI_03748 6.9e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GPPMODKI_03749 2.7e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPPMODKI_03750 2.4e-76 trpP S Tryptophan transporter TrpP
GPPMODKI_03751 5.2e-18
GPPMODKI_03752 2.4e-38 yhaH S YtxH-like protein
GPPMODKI_03753 3.3e-112 hpr K Negative regulator of protease production and sporulation
GPPMODKI_03754 9.9e-55 yhaI S Protein of unknown function (DUF1878)
GPPMODKI_03755 7e-95 yhaK S Putative zincin peptidase
GPPMODKI_03756 2.2e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GPPMODKI_03757 1.6e-32 yhaL S Sporulation protein YhaL
GPPMODKI_03758 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
GPPMODKI_03759 0.0 yhaN L AAA domain
GPPMODKI_03760 2.6e-238 yhaO L DNA repair exonuclease
GPPMODKI_03761 4e-205 yhaP CP COG1668 ABC-type Na efflux pump, permease component
GPPMODKI_03762 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
GPPMODKI_03763 4.7e-14 S YhzD-like protein
GPPMODKI_03764 2e-135 yhaR 5.3.3.18 I enoyl-CoA hydratase
GPPMODKI_03766 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
GPPMODKI_03767 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
GPPMODKI_03768 1.9e-250 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
GPPMODKI_03769 9.3e-294 hemZ H coproporphyrinogen III oxidase
GPPMODKI_03770 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
GPPMODKI_03771 2.1e-197 yhaZ L DNA alkylation repair enzyme
GPPMODKI_03772 4.4e-53 yheA S Belongs to the UPF0342 family
GPPMODKI_03773 7.9e-205 yheB S Belongs to the UPF0754 family
GPPMODKI_03774 1.8e-214 yheC HJ YheC/D like ATP-grasp
GPPMODKI_03775 3e-259 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
GPPMODKI_03776 1.7e-36 yheE S Family of unknown function (DUF5342)
GPPMODKI_03777 2.9e-28 sspB S spore protein
GPPMODKI_03779 6.2e-111 yheG GM NAD(P)H-binding
GPPMODKI_03780 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPPMODKI_03781 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPPMODKI_03783 2.1e-85 T universal stress protein
GPPMODKI_03784 1.8e-93 ymcC S Membrane
GPPMODKI_03785 3e-87 pksA K Transcriptional regulator
GPPMODKI_03786 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
GPPMODKI_03787 3.5e-157 yheN G deacetylase
GPPMODKI_03788 8.5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
GPPMODKI_03789 4.6e-205 yhdY M Mechanosensitive ion channel
GPPMODKI_03791 6.5e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GPPMODKI_03792 4.9e-61 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPPMODKI_03793 5.1e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPPMODKI_03794 2.9e-257 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
GPPMODKI_03795 4.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GPPMODKI_03796 1.2e-224 yhdR 2.6.1.1 E Aminotransferase
GPPMODKI_03797 4.3e-71 cueR K transcriptional
GPPMODKI_03798 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
GPPMODKI_03799 1.9e-109 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GPPMODKI_03800 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
GPPMODKI_03801 6.6e-201 yhdL S Sigma factor regulator N-terminal
GPPMODKI_03802 8.1e-45 yhdK S Sigma-M inhibitor protein
GPPMODKI_03803 4.4e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GPPMODKI_03804 2e-250 yhdG E amino acid
GPPMODKI_03805 4.6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPPMODKI_03806 4.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
GPPMODKI_03807 9e-164 citR K Transcriptional regulator
GPPMODKI_03808 2.2e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
GPPMODKI_03809 6.8e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
GPPMODKI_03810 8.7e-270 ycgB S Stage V sporulation protein R
GPPMODKI_03811 1.3e-255 ygxB M Conserved TM helix
GPPMODKI_03812 5.6e-74 nsrR K Transcriptional regulator
GPPMODKI_03813 2.3e-217 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
GPPMODKI_03814 9e-53 yhdC S Protein of unknown function (DUF3889)
GPPMODKI_03815 2.5e-39 yhdB S YhdB-like protein
GPPMODKI_03816 9.7e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
GPPMODKI_03817 1.4e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPPMODKI_03818 3.2e-206 yhcY 2.7.13.3 T Histidine kinase
GPPMODKI_03819 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
GPPMODKI_03820 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPPMODKI_03821 1.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPPMODKI_03822 1.9e-147 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
GPPMODKI_03823 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GPPMODKI_03824 6.4e-262 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPPMODKI_03825 1.1e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GPPMODKI_03826 4.9e-125 yhcW 5.4.2.6 S hydrolase
GPPMODKI_03827 2.6e-68 yhcV S COG0517 FOG CBS domain
GPPMODKI_03828 1.3e-69 yhcU S Family of unknown function (DUF5365)
GPPMODKI_03829 1.1e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPPMODKI_03830 2e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
GPPMODKI_03831 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
GPPMODKI_03832 7.6e-115 yhcQ M Spore coat protein
GPPMODKI_03833 3.3e-161 yhcP
GPPMODKI_03834 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GPPMODKI_03835 1.3e-51 yhcM
GPPMODKI_03836 1.9e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPPMODKI_03837 4.6e-186 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
GPPMODKI_03838 9.4e-147 metQ M Belongs to the nlpA lipoprotein family
GPPMODKI_03839 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
GPPMODKI_03840 3.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GPPMODKI_03841 4.1e-167 yhcH V ABC transporter, ATP-binding protein
GPPMODKI_03842 3.6e-126 yhcG V ABC transporter, ATP-binding protein
GPPMODKI_03843 1.6e-61 yhcF K Transcriptional regulator
GPPMODKI_03844 1.6e-52
GPPMODKI_03845 7.2e-54 yhcC
GPPMODKI_03846 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
GPPMODKI_03847 8.4e-285 yhcA EGP Major facilitator Superfamily
GPPMODKI_03848 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
GPPMODKI_03849 4.6e-74 yhbI K DNA-binding transcription factor activity
GPPMODKI_03850 1.1e-212 yhbH S Belongs to the UPF0229 family
GPPMODKI_03851 0.0 prkA T Ser protein kinase
GPPMODKI_03853 3.8e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
GPPMODKI_03854 4.7e-62 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
GPPMODKI_03855 6.6e-108 yhbD K Protein of unknown function (DUF4004)
GPPMODKI_03856 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GPPMODKI_03857 1.5e-174 yhbB S Putative amidase domain
GPPMODKI_03858 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPPMODKI_03859 4.8e-111 yhzB S B3/4 domain
GPPMODKI_03861 4.8e-23 K Transcriptional regulator
GPPMODKI_03862 7.3e-80 ygaO
GPPMODKI_03863 1.2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPPMODKI_03865 9.4e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
GPPMODKI_03866 9.8e-144 ssuC P ABC transporter (permease)
GPPMODKI_03867 1.3e-179 ssuA M Sulfonate ABC transporter
GPPMODKI_03868 9.3e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
GPPMODKI_03869 1.3e-181 S Amidohydrolase
GPPMODKI_03870 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
GPPMODKI_03871 7.4e-135 oppF3 E Belongs to the ABC transporter superfamily
GPPMODKI_03872 5.8e-135 oppD3 P Belongs to the ABC transporter superfamily
GPPMODKI_03873 3.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPPMODKI_03874 9.2e-138 appB P Binding-protein-dependent transport system inner membrane component
GPPMODKI_03875 4.4e-231 oppA5 E PFAM extracellular solute-binding protein family 5
GPPMODKI_03877 5.4e-264 ygaK C Berberine and berberine like
GPPMODKI_03878 5.3e-77 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPPMODKI_03879 3.5e-205 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPPMODKI_03880 1.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
GPPMODKI_03881 1.4e-284 C Na+/H+ antiporter family
GPPMODKI_03885 1.6e-08
GPPMODKI_03889 4.6e-28 Q PFAM Collagen triple helix
GPPMODKI_03890 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
GPPMODKI_03891 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
GPPMODKI_03892 1.3e-57 yflT S Heat induced stress protein YflT
GPPMODKI_03893 1.2e-24 S Protein of unknown function (DUF3212)
GPPMODKI_03894 5.5e-189 yfmJ S N-terminal domain of oxidoreductase
GPPMODKI_03895 2e-40 yfmK 2.3.1.128 K acetyltransferase
GPPMODKI_03896 7.9e-205 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
GPPMODKI_03897 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GPPMODKI_03898 2.1e-208 yfmO EGP Major facilitator Superfamily
GPPMODKI_03899 1.8e-69 yfmP K transcriptional
GPPMODKI_03900 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GPPMODKI_03901 1.6e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GPPMODKI_03902 1.5e-166 IQ Enoyl-(Acyl carrier protein) reductase
GPPMODKI_03903 4.9e-106 yfmS NT chemotaxis protein
GPPMODKI_03904 3.4e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPPMODKI_03905 6.6e-246 yfnA E amino acid
GPPMODKI_03906 1e-218 fsr P COG0477 Permeases of the major facilitator superfamily
GPPMODKI_03907 2.4e-186 yfnD M Nucleotide-diphospho-sugar transferase
GPPMODKI_03908 3.9e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
GPPMODKI_03909 1.8e-178 yfnF M Nucleotide-diphospho-sugar transferase
GPPMODKI_03910 2.4e-172 yfnG 4.2.1.45 M dehydratase
GPPMODKI_03911 7.9e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
GPPMODKI_03912 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GPPMODKI_03913 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
GPPMODKI_03914 7.5e-197 yetN S Protein of unknown function (DUF3900)
GPPMODKI_03915 2.4e-206 yetM CH FAD binding domain
GPPMODKI_03916 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
GPPMODKI_03917 8.2e-106 yetJ S Belongs to the BI1 family
GPPMODKI_03918 1.2e-54 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
GPPMODKI_03919 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
GPPMODKI_03920 5.9e-133 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GPPMODKI_03921 3.5e-104 cysW P COG4208 ABC-type sulfate transport system, permease component
GPPMODKI_03922 4.5e-112 cysT O COG0555 ABC-type sulfate transport system, permease component
GPPMODKI_03923 2.9e-137 sbp P COG1613 ABC-type sulfate transport system, periplasmic component
GPPMODKI_03924 1.7e-154 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GPPMODKI_03925 2.9e-63 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPPMODKI_03926 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
GPPMODKI_03927 1.3e-120 yetF S membrane
GPPMODKI_03929 3e-93 yesJ K Acetyltransferase (GNAT) family
GPPMODKI_03930 8.9e-104 cotJC P Spore Coat
GPPMODKI_03931 3.3e-45 cotJB S CotJB protein
GPPMODKI_03932 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
GPPMODKI_03933 2.4e-108 aadK G Streptomycin adenylyltransferase
GPPMODKI_03935 9.4e-127 yeeN K transcriptional regulatory protein
GPPMODKI_03936 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
GPPMODKI_03937 3e-81 S Protein of unknown function, DUF600
GPPMODKI_03939 1.3e-28 S Colicin immunity protein / pyocin immunity protein
GPPMODKI_03941 4.3e-67
GPPMODKI_03942 9.8e-115 3.6.4.12 L AAA domain
GPPMODKI_03943 2.8e-198 L AAA ATPase domain
GPPMODKI_03944 1.2e-247 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPPMODKI_03945 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GPPMODKI_03946 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPPMODKI_03947 9e-153 yerO K Transcriptional regulator
GPPMODKI_03948 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPPMODKI_03949 7.9e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GPPMODKI_03950 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPPMODKI_03951 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPPMODKI_03952 1.3e-120 sapB S MgtC SapB transporter
GPPMODKI_03953 3.8e-195 yerI S homoserine kinase type II (protein kinase fold)
GPPMODKI_03954 2.6e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
GPPMODKI_03955 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPPMODKI_03956 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GPPMODKI_03957 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GPPMODKI_03958 7.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
GPPMODKI_03959 2.4e-50 yerC S protein conserved in bacteria
GPPMODKI_03960 4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
GPPMODKI_03961 0.0 yerA 3.5.4.2 F adenine deaminase
GPPMODKI_03962 2e-25 S Protein of unknown function (DUF2892)
GPPMODKI_03963 1.8e-234 purD 6.3.4.13 F Belongs to the GARS family
GPPMODKI_03964 1.9e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GPPMODKI_03965 7e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPPMODKI_03966 1.7e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GPPMODKI_03967 8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPPMODKI_03968 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPPMODKI_03969 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPPMODKI_03970 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPPMODKI_03971 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GPPMODKI_03972 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPPMODKI_03973 3e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPPMODKI_03974 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPPMODKI_03975 5.5e-29 yebG S NETI protein
GPPMODKI_03976 3.4e-92 yebE S UPF0316 protein
GPPMODKI_03978 1.9e-125 yebC M Membrane
GPPMODKI_03979 6.2e-209 pbuG S permease
GPPMODKI_03980 4.3e-248 S Domain of unknown function (DUF4179)
GPPMODKI_03981 3e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
GPPMODKI_03982 7.7e-127 K Acetyltransferase (GNAT) domain
GPPMODKI_03983 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GPPMODKI_03984 0.0 yebA E COG1305 Transglutaminase-like enzymes
GPPMODKI_03985 1e-215 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
GPPMODKI_03986 4.6e-177 yeaC S COG0714 MoxR-like ATPases
GPPMODKI_03987 4.9e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPPMODKI_03988 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
GPPMODKI_03989 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
GPPMODKI_03990 7.2e-35 ydjO S Cold-inducible protein YdjO
GPPMODKI_03992 9.4e-136 ydjN U Involved in the tonB-independent uptake of proteins
GPPMODKI_03993 7.1e-62 ydjM M Lytic transglycolase
GPPMODKI_03994 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
GPPMODKI_03995 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
GPPMODKI_03996 2.6e-147 rsiV S Protein of unknown function (DUF3298)
GPPMODKI_03997 0.0 yrhL I Acyltransferase family
GPPMODKI_03998 3.3e-146 ydjI S virion core protein (lumpy skin disease virus)
GPPMODKI_03999 3.1e-120 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
GPPMODKI_04000 6.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPPMODKI_04001 6.7e-114 pspA KT Phage shock protein A
GPPMODKI_04002 4.3e-31 yjdJ S Domain of unknown function (DUF4306)
GPPMODKI_04003 8.3e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
GPPMODKI_04004 5.8e-250 gutA G MFS/sugar transport protein
GPPMODKI_04005 9.4e-200 gutB 1.1.1.14 E Dehydrogenase
GPPMODKI_04006 0.0 K NB-ARC domain
GPPMODKI_04007 1.5e-09 S Protein of unknown function (DUF4238)
GPPMODKI_04008 2.6e-118
GPPMODKI_04009 4e-12 3.6.4.12 KL ATP-dependent helicase activity
GPPMODKI_04010 1.8e-92 3.6.4.12 KL HELICc2
GPPMODKI_04011 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GPPMODKI_04012 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPPMODKI_04013 4.3e-127 ydiL S CAAX protease self-immunity
GPPMODKI_04014 1.7e-27 ydiK S Domain of unknown function (DUF4305)
GPPMODKI_04015 3.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPPMODKI_04016 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GPPMODKI_04017 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GPPMODKI_04018 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
GPPMODKI_04019 0.0 ydiF S ABC transporter
GPPMODKI_04020 3e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPPMODKI_04021 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GPPMODKI_04022 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
GPPMODKI_04023 2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
GPPMODKI_04024 4.3e-183 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPPMODKI_04026 8.2e-165 ygxA S Nucleotidyltransferase-like
GPPMODKI_04027 1.5e-56 ygzB S UPF0295 protein
GPPMODKI_04028 1.8e-80 perR P Belongs to the Fur family
GPPMODKI_04029 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
GPPMODKI_04030 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
GPPMODKI_04031 3.2e-179 ygaE S Membrane
GPPMODKI_04032 4.2e-306 ygaD V ABC transporter
GPPMODKI_04033 2.2e-104 ygaC J Belongs to the UPF0374 family
GPPMODKI_04034 1.5e-37 ygaB S YgaB-like protein
GPPMODKI_04036 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPPMODKI_04037 2.4e-36 yfhS
GPPMODKI_04038 1e-209 mutY L A G-specific
GPPMODKI_04039 1.5e-183 yfhP S membrane-bound metal-dependent
GPPMODKI_04040 0.0 yfhO S Bacterial membrane protein YfhO
GPPMODKI_04041 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GPPMODKI_04042 1.8e-169 yfhM S Alpha/beta hydrolase family
GPPMODKI_04043 4.4e-34 yfhL S SdpI/YhfL protein family
GPPMODKI_04044 1e-93 batE T Bacterial SH3 domain homologues
GPPMODKI_04045 2.2e-44 yfhJ S WVELL protein
GPPMODKI_04046 1.4e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
GPPMODKI_04048 4.5e-206 yfhI EGP Major facilitator Superfamily
GPPMODKI_04049 8.8e-53 yfhH S Protein of unknown function (DUF1811)
GPPMODKI_04050 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
GPPMODKI_04051 1.4e-167 yfhF S nucleoside-diphosphate sugar epimerase
GPPMODKI_04053 2.1e-25 yfhD S YfhD-like protein
GPPMODKI_04054 1.3e-105 yfhC C nitroreductase
GPPMODKI_04055 2.4e-164 yfhB 5.3.3.17 S PhzF family
GPPMODKI_04056 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPPMODKI_04057 5.6e-83 yfiV K transcriptional
GPPMODKI_04058 3.6e-288 yfiU EGP Major facilitator Superfamily
GPPMODKI_04059 1.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
GPPMODKI_04060 1.5e-45 yrdF K ribonuclease inhibitor
GPPMODKI_04061 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
GPPMODKI_04062 7.7e-181 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GPPMODKI_04063 5.5e-112 1.6.5.2 S NADPH-dependent FMN reductase
GPPMODKI_04064 3e-96 padR K transcriptional
GPPMODKI_04065 3.1e-170 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GPPMODKI_04066 8.6e-194 S Oxidoreductase
GPPMODKI_04067 1.6e-77 G Xylose isomerase
GPPMODKI_04068 1.6e-68 G Xylose isomerase
GPPMODKI_04069 1.6e-192 iolT EGP Major facilitator Superfamily
GPPMODKI_04070 8.4e-99 K AraC-like ligand binding domain
GPPMODKI_04071 7e-161 yfiE 1.13.11.2 S glyoxalase
GPPMODKI_04072 7e-63 mhqP S DoxX
GPPMODKI_04073 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPPMODKI_04074 0.0 yfiB3 V ABC transporter
GPPMODKI_04075 8.3e-293 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPPMODKI_04076 5.6e-138 glvR F Helix-turn-helix domain, rpiR family
GPPMODKI_04077 3.4e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GPPMODKI_04078 4.2e-15 sspH S Belongs to the SspH family
GPPMODKI_04079 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
GPPMODKI_04080 6.6e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GPPMODKI_04081 1.4e-215 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPPMODKI_04082 3.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GPPMODKI_04083 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GPPMODKI_04084 1.3e-95 yfjM S Psort location Cytoplasmic, score
GPPMODKI_04085 3e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPPMODKI_04086 3.8e-31 S YfzA-like protein
GPPMODKI_04087 4.8e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPPMODKI_04088 6.3e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPPMODKI_04089 2.1e-182 corA P Mediates influx of magnesium ions
GPPMODKI_04090 2.3e-31
GPPMODKI_04091 6.8e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
GPPMODKI_04092 9e-155 pdaA G deacetylase
GPPMODKI_04093 4.9e-27 yfjT
GPPMODKI_04094 3e-220 yfkA S YfkB-like domain
GPPMODKI_04095 1.6e-146 yfkC M Mechanosensitive ion channel
GPPMODKI_04096 1.6e-143 yfkD S YfkD-like protein
GPPMODKI_04097 1.3e-185 cax P COG0387 Ca2 H antiporter
GPPMODKI_04098 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
GPPMODKI_04100 2.6e-144 yihY S Belongs to the UPF0761 family
GPPMODKI_04101 2.2e-51 yfkI S gas vesicle protein
GPPMODKI_04102 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPPMODKI_04103 2.7e-29 yfkK S Belongs to the UPF0435 family
GPPMODKI_04104 7.3e-193 ydiM EGP Major facilitator Superfamily
GPPMODKI_04105 1.7e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GPPMODKI_04106 1.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPPMODKI_04107 9.8e-186 K helix_turn _helix lactose operon repressor
GPPMODKI_04108 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
GPPMODKI_04109 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
GPPMODKI_04110 2.3e-193 yibE S YibE/F-like protein
GPPMODKI_04111 1.2e-124 yibF S YibE/F-like protein
GPPMODKI_04112 1.2e-123 yfkO C nitroreductase
GPPMODKI_04113 9e-130 treR K transcriptional
GPPMODKI_04114 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
GPPMODKI_04115 4.3e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPPMODKI_04116 1.5e-37 ydgB S Spore germination protein gerPA/gerPF
GPPMODKI_04117 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
GPPMODKI_04118 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
GPPMODKI_04119 7.8e-64 yhdN S Domain of unknown function (DUF1992)
GPPMODKI_04120 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GPPMODKI_04121 4.1e-72 yfmQ S Uncharacterised protein from bacillus cereus group
GPPMODKI_04122 1.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
GPPMODKI_04123 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
GPPMODKI_04124 2e-49 yflH S Protein of unknown function (DUF3243)
GPPMODKI_04125 7e-19 yflI
GPPMODKI_04126 1.5e-14 yflJ S Protein of unknown function (DUF2639)
GPPMODKI_04127 5.8e-123 yflK S protein conserved in bacteria
GPPMODKI_04128 8.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GPPMODKI_04129 7.1e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GPPMODKI_04130 8.7e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
GPPMODKI_04131 8.5e-227 citM C Citrate transporter
GPPMODKI_04132 6.6e-176 yflP S Tripartite tricarboxylate transporter family receptor
GPPMODKI_04133 4e-119 citT T response regulator
GPPMODKI_04134 6e-275 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
GPPMODKI_04135 2.7e-80 srtA 3.4.22.70 M Sortase family
GPPMODKI_04136 0.0 M1-568 M cell wall anchor domain
GPPMODKI_04137 9.5e-156 M1-568 M cell wall anchor domain
GPPMODKI_04138 4.1e-150 M1-574 T Transcriptional regulatory protein, C terminal
GPPMODKI_04139 0.0 ywpD T PhoQ Sensor
GPPMODKI_04140 8.3e-78 M1-820 Q Collagen triple helix repeat (20 copies)
GPPMODKI_04141 7.5e-77 ctsR K Belongs to the CtsR family
GPPMODKI_04142 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
GPPMODKI_04143 5.5e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
GPPMODKI_04144 0.0 clpC O Belongs to the ClpA ClpB family
GPPMODKI_04145 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPPMODKI_04146 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GPPMODKI_04147 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
GPPMODKI_04148 5.2e-122 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
GPPMODKI_04149 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
GPPMODKI_04150 9e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPPMODKI_04151 1e-116 cysE 2.3.1.30 E Serine acetyltransferase
GPPMODKI_04152 9e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPPMODKI_04153 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GPPMODKI_04154 1.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPPMODKI_04155 4.2e-89 yacP S RNA-binding protein containing a PIN domain
GPPMODKI_04156 8.9e-116 sigH K Belongs to the sigma-70 factor family
GPPMODKI_04157 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GPPMODKI_04158 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
GPPMODKI_04159 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPPMODKI_04160 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GPPMODKI_04161 2.5e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPPMODKI_04162 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GPPMODKI_04163 6.3e-108 rsmC 2.1.1.172 J Methyltransferase
GPPMODKI_04164 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPPMODKI_04165 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPPMODKI_04166 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
GPPMODKI_04167 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GPPMODKI_04168 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GPPMODKI_04169 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPPMODKI_04170 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPPMODKI_04171 2.6e-188 ybaC 3.4.11.5 S Alpha/beta hydrolase family
GPPMODKI_04172 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
GPPMODKI_04173 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPPMODKI_04174 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
GPPMODKI_04175 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GPPMODKI_04176 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPPMODKI_04177 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPPMODKI_04178 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPPMODKI_04179 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPPMODKI_04180 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPPMODKI_04181 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
GPPMODKI_04182 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPPMODKI_04183 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPPMODKI_04184 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPPMODKI_04185 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPPMODKI_04186 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPPMODKI_04187 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPPMODKI_04188 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPPMODKI_04189 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPPMODKI_04190 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPPMODKI_04191 1.9e-23 rpmD J Ribosomal protein L30
GPPMODKI_04192 1.1e-72 rplO J binds to the 23S rRNA
GPPMODKI_04193 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GPPMODKI_04194 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GPPMODKI_04195 1.4e-141 map 3.4.11.18 E Methionine aminopeptidase
GPPMODKI_04196 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPPMODKI_04197 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GPPMODKI_04198 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPPMODKI_04199 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPPMODKI_04200 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPPMODKI_04201 4.7e-58 rplQ J Ribosomal protein L17
GPPMODKI_04202 1.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPPMODKI_04203 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPPMODKI_04204 1.3e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPPMODKI_04205 1.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GPPMODKI_04206 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPPMODKI_04207 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
GPPMODKI_04208 1.2e-143 ybaJ Q Methyltransferase domain
GPPMODKI_04209 3.6e-82 yizA S Damage-inducible protein DinB
GPPMODKI_04210 4.5e-79 ybaK S Protein of unknown function (DUF2521)
GPPMODKI_04211 7.9e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GPPMODKI_04212 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
GPPMODKI_04213 1.7e-75 gerD
GPPMODKI_04214 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
GPPMODKI_04215 2.5e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)