ORF_ID e_value Gene_name EC_number CAZy COGs Description
KPFMNBKC_00001 1.1e-56 yisS 1.1.1.370 S Oxidoreductase family, NAD-binding Rossmann fold
KPFMNBKC_00002 6.6e-159 yisR K Transcriptional regulator
KPFMNBKC_00003 2.5e-245 yisQ V Mate efflux family protein
KPFMNBKC_00004 1.2e-132 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
KPFMNBKC_00005 0.0 asnO 6.3.5.4 E Asparagine synthase
KPFMNBKC_00006 7.6e-97 yisN S Protein of unknown function (DUF2777)
KPFMNBKC_00007 1.1e-59 yisL S UPF0344 protein
KPFMNBKC_00008 1.2e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KPFMNBKC_00009 5e-07 yisI S Spo0E like sporulation regulatory protein
KPFMNBKC_00010 8.4e-34 gerPA S Spore germination protein
KPFMNBKC_00011 6.2e-35 gerPB S cell differentiation
KPFMNBKC_00012 1.4e-62 gerPC S Spore germination protein
KPFMNBKC_00013 3.1e-23 gerPD S Spore germination protein
KPFMNBKC_00014 3.1e-63 gerPE S Spore germination protein GerPE
KPFMNBKC_00015 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
KPFMNBKC_00016 2.9e-50 yisB V COG1403 Restriction endonuclease
KPFMNBKC_00017 0.0 sbcC L COG0419 ATPase involved in DNA repair
KPFMNBKC_00018 3.3e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KPFMNBKC_00019 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KPFMNBKC_00020 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KPFMNBKC_00021 1.1e-124 ydfS S Protein of unknown function (DUF421)
KPFMNBKC_00022 9.7e-94 yhjR S Rubrerythrin
KPFMNBKC_00023 4.6e-106 K QacR-like protein, C-terminal region
KPFMNBKC_00024 2.3e-202 blt EGP Major facilitator Superfamily
KPFMNBKC_00025 4.8e-181 abrB S membrane
KPFMNBKC_00026 1.1e-92 yhjH K helix_turn_helix multiple antibiotic resistance protein
KPFMNBKC_00027 5.9e-277 yhjG CH FAD binding domain
KPFMNBKC_00029 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
KPFMNBKC_00030 4.5e-109 yhjE S SNARE associated Golgi protein
KPFMNBKC_00031 2.2e-60 yhjD
KPFMNBKC_00032 1.4e-27 yhjC S Protein of unknown function (DUF3311)
KPFMNBKC_00033 3.2e-267 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KPFMNBKC_00034 3.3e-47 S Belongs to the UPF0145 family
KPFMNBKC_00035 1.6e-42 yhjA S Excalibur calcium-binding domain
KPFMNBKC_00036 1.5e-124 yrpD S Domain of unknown function, YrpD
KPFMNBKC_00037 1.3e-168 els S Acetyltransferase, GNAT family
KPFMNBKC_00038 2.4e-92 mepB S MepB protein
KPFMNBKC_00039 1.4e-65 frataxin S Domain of unknown function (DU1801)
KPFMNBKC_00040 3.9e-68 frataxin S Domain of unknown function (DU1801)
KPFMNBKC_00041 1.9e-109 comK K Competence transcription factor
KPFMNBKC_00042 1.8e-31 yhzC S IDEAL
KPFMNBKC_00043 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KPFMNBKC_00044 3.1e-297 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KPFMNBKC_00045 4.5e-196 hemAT NT chemotaxis protein
KPFMNBKC_00046 5.1e-88 bioY S BioY family
KPFMNBKC_00047 5.6e-280 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KPFMNBKC_00048 1.5e-200 vraB 2.3.1.9 I Belongs to the thiolase family
KPFMNBKC_00049 1.7e-102 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KPFMNBKC_00050 9.3e-153 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KPFMNBKC_00051 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
KPFMNBKC_00052 1.7e-237 yhfN 3.4.24.84 O Peptidase M48
KPFMNBKC_00053 1.9e-65 yhfM
KPFMNBKC_00054 6.4e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KPFMNBKC_00055 7.7e-112 yhfK GM NmrA-like family
KPFMNBKC_00056 1e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
KPFMNBKC_00057 1.1e-138 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KPFMNBKC_00058 3.4e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KPFMNBKC_00059 4.3e-197 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
KPFMNBKC_00061 9.6e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPFMNBKC_00062 5e-270 yhgE S YhgE Pip N-terminal domain protein
KPFMNBKC_00063 1.2e-100 yhgD K Transcriptional regulator
KPFMNBKC_00064 1e-273 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KPFMNBKC_00065 2.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KPFMNBKC_00066 4.3e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KPFMNBKC_00067 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KPFMNBKC_00068 7.8e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KPFMNBKC_00069 1.1e-243 yhfA C membrane
KPFMNBKC_00070 1.6e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KPFMNBKC_00071 6.2e-123 ecsC S EcsC protein family
KPFMNBKC_00072 5e-221 ecsB U ABC transporter
KPFMNBKC_00073 1.7e-134 ecsA V transporter (ATP-binding protein)
KPFMNBKC_00074 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KPFMNBKC_00075 1e-201 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KPFMNBKC_00076 2.9e-77 trpP S Tryptophan transporter TrpP
KPFMNBKC_00077 2e-17
KPFMNBKC_00078 1.4e-38 yhaH S YtxH-like protein
KPFMNBKC_00079 3.3e-112 hpr K Negative regulator of protease production and sporulation
KPFMNBKC_00080 9.9e-55 yhaI S Protein of unknown function (DUF1878)
KPFMNBKC_00081 7e-95 yhaK S Putative zincin peptidase
KPFMNBKC_00082 2.6e-115 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KPFMNBKC_00083 1.6e-32 yhaL S Sporulation protein YhaL
KPFMNBKC_00084 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
KPFMNBKC_00085 0.0 yhaN L AAA domain
KPFMNBKC_00086 5e-237 yhaO L DNA repair exonuclease
KPFMNBKC_00087 8e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KPFMNBKC_00088 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
KPFMNBKC_00089 7.3e-15 S YhzD-like protein
KPFMNBKC_00090 2e-135 yhaR 5.3.3.18 I enoyl-CoA hydratase
KPFMNBKC_00092 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
KPFMNBKC_00093 4.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
KPFMNBKC_00094 5.8e-252 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
KPFMNBKC_00095 9.3e-294 hemZ H coproporphyrinogen III oxidase
KPFMNBKC_00096 3.3e-158 yhaX S haloacid dehalogenase-like hydrolase
KPFMNBKC_00097 2.6e-203 yhaZ L DNA alkylation repair enzyme
KPFMNBKC_00098 4.4e-53 yheA S Belongs to the UPF0342 family
KPFMNBKC_00099 3.6e-205 yheB S Belongs to the UPF0754 family
KPFMNBKC_00100 6.9e-214 yheC HJ YheC/D like ATP-grasp
KPFMNBKC_00101 2.5e-261 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KPFMNBKC_00102 1.7e-36 yheE S Family of unknown function (DUF5342)
KPFMNBKC_00103 5.8e-29 sspB S spore protein
KPFMNBKC_00105 4.8e-111 yheG GM NAD(P)H-binding
KPFMNBKC_00106 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KPFMNBKC_00107 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KPFMNBKC_00109 4e-84 T universal stress protein
KPFMNBKC_00110 1.8e-93 ymcC S Membrane
KPFMNBKC_00111 4.6e-88 pksA K Transcriptional regulator
KPFMNBKC_00112 5.3e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KPFMNBKC_00113 1e-156 yheN G deacetylase
KPFMNBKC_00114 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KPFMNBKC_00115 1.6e-205 yhdY M Mechanosensitive ion channel
KPFMNBKC_00117 1e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KPFMNBKC_00118 2.1e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KPFMNBKC_00119 6.1e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KPFMNBKC_00120 3.5e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
KPFMNBKC_00121 5.6e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KPFMNBKC_00122 5.5e-225 yhdR 2.6.1.1 E Aminotransferase
KPFMNBKC_00123 4.3e-71 cueR K transcriptional
KPFMNBKC_00124 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KPFMNBKC_00125 1.9e-109 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KPFMNBKC_00126 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
KPFMNBKC_00127 1.3e-201 yhdL S Sigma factor regulator N-terminal
KPFMNBKC_00128 8.1e-45 yhdK S Sigma-M inhibitor protein
KPFMNBKC_00129 4.4e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KPFMNBKC_00130 1.7e-249 yhdG E amino acid
KPFMNBKC_00131 1.3e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KPFMNBKC_00132 2.7e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
KPFMNBKC_00133 9e-164 citR K Transcriptional regulator
KPFMNBKC_00134 6.3e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KPFMNBKC_00135 7.5e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KPFMNBKC_00136 3.6e-271 ycgB S Stage V sporulation protein R
KPFMNBKC_00137 2.7e-256 ygxB M Conserved TM helix
KPFMNBKC_00138 1.6e-73 nsrR K Transcriptional regulator
KPFMNBKC_00139 6.8e-217 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KPFMNBKC_00140 1.1e-53 yhdC S Protein of unknown function (DUF3889)
KPFMNBKC_00141 2.5e-39 yhdB S YhdB-like protein
KPFMNBKC_00142 7.4e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
KPFMNBKC_00143 2.5e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KPFMNBKC_00144 1.3e-207 yhcY 2.7.13.3 T Histidine kinase
KPFMNBKC_00145 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KPFMNBKC_00146 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KPFMNBKC_00147 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KPFMNBKC_00148 1.2e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KPFMNBKC_00149 3.4e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KPFMNBKC_00150 3.2e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KPFMNBKC_00151 3.9e-210 tcaB EGP Major facilitator Superfamily
KPFMNBKC_00152 3e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KPFMNBKC_00153 3.2e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
KPFMNBKC_00154 4.2e-100 ynaD J Acetyltransferase (GNAT) domain
KPFMNBKC_00155 2.7e-299 expZ S ABC transporter
KPFMNBKC_00156 4.7e-134 puuD S Peptidase C26
KPFMNBKC_00157 0.0 ydfJ S drug exporters of the RND superfamily
KPFMNBKC_00158 8.3e-111 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KPFMNBKC_00159 1.8e-213 ydfH 2.7.13.3 T Histidine kinase
KPFMNBKC_00160 1.2e-36 yraG
KPFMNBKC_00161 6.4e-63 yraF M Spore coat protein
KPFMNBKC_00162 4.2e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KPFMNBKC_00163 7.5e-26 yraE
KPFMNBKC_00164 9.5e-49 yraD M Spore coat protein
KPFMNBKC_00165 3.1e-267 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KPFMNBKC_00166 1.5e-155 ydeK EG -transporter
KPFMNBKC_00167 8.4e-102 ydeS K Transcriptional regulator
KPFMNBKC_00168 1.9e-180 ydeR EGP Major facilitator Superfamily
KPFMNBKC_00170 7.1e-115 paiB K Transcriptional regulator
KPFMNBKC_00171 9.2e-264 K helix_turn_helix gluconate operon transcriptional repressor
KPFMNBKC_00172 6.2e-222 mleN_2 C antiporter
KPFMNBKC_00173 3.6e-67 yraB K helix_turn_helix, mercury resistance
KPFMNBKC_00174 2.2e-201 adhA 1.1.1.1 C alcohol dehydrogenase
KPFMNBKC_00175 1.6e-166 S Sodium Bile acid symporter family
KPFMNBKC_00176 2.6e-51 ydeH
KPFMNBKC_00177 4.6e-199 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
KPFMNBKC_00179 2e-148 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
KPFMNBKC_00180 5.2e-66 ykkA S Protein of unknown function (DUF664)
KPFMNBKC_00181 9e-98 yrkC G Cupin domain
KPFMNBKC_00183 6.4e-201 trkA P Oxidoreductase
KPFMNBKC_00184 3.8e-168 czcD P COG1230 Co Zn Cd efflux system component
KPFMNBKC_00185 2e-76 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KPFMNBKC_00186 6e-268 ygaK C COG0277 FAD FMN-containing dehydrogenases
KPFMNBKC_00189 1e-47 G Cupin domain
KPFMNBKC_00190 1.7e-84 S DinB superfamily
KPFMNBKC_00191 1.6e-182 S Patatin-like phospholipase
KPFMNBKC_00192 1.1e-234 ybfB G COG0477 Permeases of the major facilitator superfamily
KPFMNBKC_00193 1.1e-86 ybfA 3.4.15.5 K FR47-like protein
KPFMNBKC_00194 1.3e-51 K Transcriptional regulator PadR-like family
KPFMNBKC_00195 2.8e-102 S Protein of unknown function (DUF2812)
KPFMNBKC_00196 6.6e-122 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KPFMNBKC_00197 4.7e-79 carD K Transcription factor
KPFMNBKC_00198 5.2e-30 cspL K Cold shock
KPFMNBKC_00199 1.8e-195 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KPFMNBKC_00200 2.2e-54 K Transcriptional regulator
KPFMNBKC_00201 3.5e-177 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KPFMNBKC_00202 8.7e-75 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KPFMNBKC_00203 0.0 M Domain of unknown function DUF11
KPFMNBKC_00204 1.4e-108 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KPFMNBKC_00205 7.7e-50 S SMI1-KNR4 cell-wall
KPFMNBKC_00207 3.8e-111 ywnB S NAD(P)H-binding
KPFMNBKC_00208 4.8e-73 ywnA K Transcriptional regulator
KPFMNBKC_00209 3.2e-64 yyaQ S YjbR
KPFMNBKC_00210 1e-72 maoC I N-terminal half of MaoC dehydratase
KPFMNBKC_00211 8.5e-57 S Domain of unknown function with cystatin-like fold (DUF4467)
KPFMNBKC_00212 4.5e-49 ohrR K Transcriptional regulator
KPFMNBKC_00213 5.2e-230 proP EGP Transporter
KPFMNBKC_00214 1.6e-25 G Cupin domain
KPFMNBKC_00215 1.4e-150 S Serine aminopeptidase, S33
KPFMNBKC_00216 3.5e-70 lrpA K transcriptional
KPFMNBKC_00217 1.4e-141 yddR S Zn-dependent hydrolases of the beta-lactamase fold
KPFMNBKC_00218 6.5e-72 S SnoaL-like polyketide cyclase
KPFMNBKC_00219 2.8e-96 ywrO S Flavodoxin-like fold
KPFMNBKC_00220 5.5e-08
KPFMNBKC_00228 2.8e-57 ydcK S Belongs to the SprT family
KPFMNBKC_00229 1.7e-14
KPFMNBKC_00230 0.0 yhgF K COG2183 Transcriptional accessory protein
KPFMNBKC_00231 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KPFMNBKC_00232 6.9e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KPFMNBKC_00233 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KPFMNBKC_00234 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
KPFMNBKC_00235 2.3e-187 rsbU 3.1.3.3 KT phosphatase
KPFMNBKC_00236 1.9e-68 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KPFMNBKC_00237 6.8e-57 rsbS T antagonist
KPFMNBKC_00238 6.1e-146 rsbR T Positive regulator of sigma-B
KPFMNBKC_00239 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KPFMNBKC_00240 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KPFMNBKC_00241 5.3e-220 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPFMNBKC_00242 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KPFMNBKC_00243 4.7e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KPFMNBKC_00244 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KPFMNBKC_00245 3.7e-263 ydbT S Membrane
KPFMNBKC_00246 8.1e-82 ydbS S Bacterial PH domain
KPFMNBKC_00247 3.4e-248 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KPFMNBKC_00248 3.1e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KPFMNBKC_00249 3.5e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KPFMNBKC_00250 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KPFMNBKC_00251 6.9e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPFMNBKC_00252 1.5e-10 S Fur-regulated basic protein B
KPFMNBKC_00253 3.8e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KPFMNBKC_00254 6.1e-52 ydbL
KPFMNBKC_00255 3.7e-113 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KPFMNBKC_00256 1.5e-172 ydbJ V ABC transporter, ATP-binding protein
KPFMNBKC_00257 1.3e-156 ydbI S AI-2E family transporter
KPFMNBKC_00258 5e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KPFMNBKC_00259 7.4e-118 dctR T COG4565 Response regulator of citrate malate metabolism
KPFMNBKC_00260 1.2e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KPFMNBKC_00261 1.6e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KPFMNBKC_00262 6.5e-156 ydbD P Catalase
KPFMNBKC_00263 5.3e-62 ydbC S Domain of unknown function (DUF4937
KPFMNBKC_00264 7.5e-58 ydbB G Cupin domain
KPFMNBKC_00266 1.5e-141 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
KPFMNBKC_00267 7e-54 yvaE P Small Multidrug Resistance protein
KPFMNBKC_00268 1.7e-69 yvaD S Family of unknown function (DUF5360)
KPFMNBKC_00269 1.4e-33 ydaT
KPFMNBKC_00271 3.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
KPFMNBKC_00272 2.1e-39
KPFMNBKC_00273 4.3e-98
KPFMNBKC_00274 5.3e-77
KPFMNBKC_00276 1.1e-20 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KPFMNBKC_00277 4.2e-35 xkdS S Protein of unknown function (DUF2634)
KPFMNBKC_00278 1.1e-108 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KPFMNBKC_00279 2.9e-33 xkdR S Protein of unknown function (DUF2577)
KPFMNBKC_00280 7.3e-87 yqbQ 3.2.1.96 G NLP P60 protein
KPFMNBKC_00282 4.3e-15
KPFMNBKC_00283 6.7e-67 K acetyltransferase
KPFMNBKC_00284 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KPFMNBKC_00285 9.4e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KPFMNBKC_00286 0.0 ydaO E amino acid
KPFMNBKC_00287 0.0 ydaN S Bacterial cellulose synthase subunit
KPFMNBKC_00288 2.7e-230 ydaM M Glycosyl transferase family group 2
KPFMNBKC_00289 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
KPFMNBKC_00290 3e-148 ydaK T Diguanylate cyclase, GGDEF domain
KPFMNBKC_00291 2.8e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
KPFMNBKC_00292 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KPFMNBKC_00293 1.5e-74 lrpC K Transcriptional regulator
KPFMNBKC_00294 1.3e-47 ydzA EGP Major facilitator Superfamily
KPFMNBKC_00295 6.8e-69 yrrS S Protein of unknown function (DUF1510)
KPFMNBKC_00296 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
KPFMNBKC_00297 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KPFMNBKC_00298 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
KPFMNBKC_00299 2.7e-246 yegQ O COG0826 Collagenase and related proteases
KPFMNBKC_00300 6.6e-173 yegQ O Peptidase U32
KPFMNBKC_00301 3.6e-117 yrrM 2.1.1.104 S O-methyltransferase
KPFMNBKC_00302 5.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KPFMNBKC_00303 7.1e-46 yrzB S Belongs to the UPF0473 family
KPFMNBKC_00304 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KPFMNBKC_00305 1.7e-41 yrzL S Belongs to the UPF0297 family
KPFMNBKC_00306 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KPFMNBKC_00307 6.4e-164 yrrI S AI-2E family transporter
KPFMNBKC_00308 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KPFMNBKC_00309 3.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
KPFMNBKC_00310 1.2e-109 gluC P ABC transporter
KPFMNBKC_00311 4.4e-107 glnP P ABC transporter
KPFMNBKC_00312 2.1e-08 S Protein of unknown function (DUF3918)
KPFMNBKC_00313 2.9e-30 yrzR
KPFMNBKC_00314 1.8e-83 yrrD S protein conserved in bacteria
KPFMNBKC_00315 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KPFMNBKC_00316 1.7e-18 S COG0457 FOG TPR repeat
KPFMNBKC_00317 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KPFMNBKC_00318 5.2e-212 iscS 2.8.1.7 E Cysteine desulfurase
KPFMNBKC_00319 7.8e-64 cymR K Transcriptional regulator
KPFMNBKC_00320 1.7e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KPFMNBKC_00321 7.4e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KPFMNBKC_00322 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KPFMNBKC_00323 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
KPFMNBKC_00326 6.3e-261 lytH 3.5.1.28 M COG3103 SH3 domain protein
KPFMNBKC_00327 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KPFMNBKC_00328 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KPFMNBKC_00329 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPFMNBKC_00330 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KPFMNBKC_00331 5.7e-47 yrvD S Lipopolysaccharide assembly protein A domain
KPFMNBKC_00332 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
KPFMNBKC_00333 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KPFMNBKC_00334 4.2e-49 yrzD S Post-transcriptional regulator
KPFMNBKC_00335 9.4e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KPFMNBKC_00336 9.5e-110 yrbG S membrane
KPFMNBKC_00337 2.4e-60 yrzE S Protein of unknown function (DUF3792)
KPFMNBKC_00338 5.6e-37 yajC U Preprotein translocase subunit YajC
KPFMNBKC_00339 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KPFMNBKC_00340 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KPFMNBKC_00341 1.6e-20 yrzS S Protein of unknown function (DUF2905)
KPFMNBKC_00342 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KPFMNBKC_00343 1.3e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KPFMNBKC_00344 3.7e-93 bofC S BofC C-terminal domain
KPFMNBKC_00346 6.7e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KPFMNBKC_00347 1.2e-147 safA M spore coat assembly protein SafA
KPFMNBKC_00348 9.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KPFMNBKC_00349 4.9e-151 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KPFMNBKC_00350 6.5e-298 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KPFMNBKC_00351 2.9e-223 nifS 2.8.1.7 E Cysteine desulfurase
KPFMNBKC_00352 1.5e-92 niaR S small molecule binding protein (contains 3H domain)
KPFMNBKC_00353 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
KPFMNBKC_00354 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
KPFMNBKC_00355 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KPFMNBKC_00356 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KPFMNBKC_00357 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KPFMNBKC_00358 3.2e-56 ysxB J ribosomal protein
KPFMNBKC_00359 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
KPFMNBKC_00360 7.8e-160 spoIVFB S Stage IV sporulation protein
KPFMNBKC_00361 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KPFMNBKC_00362 8e-143 minD D Belongs to the ParA family
KPFMNBKC_00363 8.7e-90 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KPFMNBKC_00364 1.4e-84 mreD M shape-determining protein
KPFMNBKC_00365 1.2e-157 mreC M Involved in formation and maintenance of cell shape
KPFMNBKC_00366 4e-184 mreB D Rod shape-determining protein MreB
KPFMNBKC_00367 1.8e-127 radC E Belongs to the UPF0758 family
KPFMNBKC_00368 3.5e-100 maf D septum formation protein Maf
KPFMNBKC_00369 3.3e-138 spoIIB S Sporulation related domain
KPFMNBKC_00370 3.3e-104 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KPFMNBKC_00371 6.2e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KPFMNBKC_00372 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KPFMNBKC_00373 2.1e-25
KPFMNBKC_00374 2.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KPFMNBKC_00375 2.3e-228 spoVID M stage VI sporulation protein D
KPFMNBKC_00376 1.8e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KPFMNBKC_00377 1.7e-184 hemB 4.2.1.24 H Belongs to the ALAD family
KPFMNBKC_00378 1e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KPFMNBKC_00379 6.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KPFMNBKC_00380 3.6e-146 hemX O cytochrome C
KPFMNBKC_00381 7.7e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KPFMNBKC_00382 1.4e-86 ysxD
KPFMNBKC_00383 3.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KPFMNBKC_00384 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KPFMNBKC_00385 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
KPFMNBKC_00386 2.2e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KPFMNBKC_00387 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KPFMNBKC_00388 4.1e-189 ysoA H Tetratricopeptide repeat
KPFMNBKC_00389 2.4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KPFMNBKC_00390 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KPFMNBKC_00391 9.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KPFMNBKC_00392 1.4e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KPFMNBKC_00393 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KPFMNBKC_00394 2.3e-82 ilvN 2.2.1.6 E Acetolactate synthase
KPFMNBKC_00395 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KPFMNBKC_00400 4.5e-91 ysnB S Phosphoesterase
KPFMNBKC_00401 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KPFMNBKC_00402 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KPFMNBKC_00403 8.1e-199 gerM S COG5401 Spore germination protein
KPFMNBKC_00404 7.8e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KPFMNBKC_00405 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
KPFMNBKC_00406 2e-30 gerE K Transcriptional regulator
KPFMNBKC_00407 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
KPFMNBKC_00408 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KPFMNBKC_00409 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KPFMNBKC_00410 4.8e-108 sdhC C succinate dehydrogenase
KPFMNBKC_00411 1.2e-79 yslB S Protein of unknown function (DUF2507)
KPFMNBKC_00412 1.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KPFMNBKC_00413 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KPFMNBKC_00414 2.5e-52 trxA O Belongs to the thioredoxin family
KPFMNBKC_00415 6.2e-298 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
KPFMNBKC_00416 5.5e-178 etfA C Electron transfer flavoprotein
KPFMNBKC_00417 2e-138 etfB C Electron transfer flavoprotein
KPFMNBKC_00418 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KPFMNBKC_00419 9.2e-104 fadR K Transcriptional regulator
KPFMNBKC_00420 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KPFMNBKC_00421 2.2e-117 ywbB S Protein of unknown function (DUF2711)
KPFMNBKC_00422 4.1e-89 yisT S DinB family
KPFMNBKC_00423 1.2e-74 argO S Lysine exporter protein LysE YggA
KPFMNBKC_00424 2.6e-192 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KPFMNBKC_00425 1.3e-71 mcbG S Pentapeptide repeats (9 copies)
KPFMNBKC_00426 1.3e-78 yjcF S Acetyltransferase (GNAT) domain
KPFMNBKC_00427 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KPFMNBKC_00428 6.6e-55 yajQ S Belongs to the UPF0234 family
KPFMNBKC_00429 1.2e-160 cvfB S protein conserved in bacteria
KPFMNBKC_00430 2.6e-172 yufN S ABC transporter substrate-binding protein PnrA-like
KPFMNBKC_00431 1.1e-231 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KPFMNBKC_00432 1.4e-242 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KPFMNBKC_00434 4.9e-159 yitS S protein conserved in bacteria
KPFMNBKC_00435 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
KPFMNBKC_00436 2.7e-79 ipi S Intracellular proteinase inhibitor
KPFMNBKC_00437 4.4e-26 S Protein of unknown function (DUF3813)
KPFMNBKC_00438 3.5e-07
KPFMNBKC_00439 1.7e-153 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KPFMNBKC_00440 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KPFMNBKC_00441 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
KPFMNBKC_00442 1.5e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KPFMNBKC_00443 2.6e-269 yitY C D-arabinono-1,4-lactone oxidase
KPFMNBKC_00444 1.2e-89 norB G Major Facilitator Superfamily
KPFMNBKC_00445 5.2e-195 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KPFMNBKC_00446 1.8e-226 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KPFMNBKC_00447 5.4e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
KPFMNBKC_00448 5.8e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KPFMNBKC_00449 6.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KPFMNBKC_00450 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KPFMNBKC_00451 2.3e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KPFMNBKC_00452 1.2e-27 yjzC S YjzC-like protein
KPFMNBKC_00453 1.5e-23 yjzD S Protein of unknown function (DUF2929)
KPFMNBKC_00454 4.2e-138 yjaU I carboxylic ester hydrolase activity
KPFMNBKC_00455 8.8e-104 yjaV
KPFMNBKC_00456 7.2e-166 med S Transcriptional activator protein med
KPFMNBKC_00457 1.1e-26 comZ S ComZ
KPFMNBKC_00458 5.9e-32 yjzB
KPFMNBKC_00459 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPFMNBKC_00460 7.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KPFMNBKC_00461 1.6e-148 yjaZ O Zn-dependent protease
KPFMNBKC_00462 1.4e-181 appD P Belongs to the ABC transporter superfamily
KPFMNBKC_00463 2.2e-187 appF E Belongs to the ABC transporter superfamily
KPFMNBKC_00464 4e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
KPFMNBKC_00465 7e-170 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPFMNBKC_00466 3.6e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPFMNBKC_00467 5.5e-146 yjbA S Belongs to the UPF0736 family
KPFMNBKC_00468 8e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KPFMNBKC_00469 0.0 oppA E ABC transporter substrate-binding protein
KPFMNBKC_00470 1.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPFMNBKC_00471 2.4e-159 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPFMNBKC_00472 2.7e-202 oppD P Belongs to the ABC transporter superfamily
KPFMNBKC_00473 2.7e-171 oppF E Belongs to the ABC transporter superfamily
KPFMNBKC_00474 1.1e-231 S Putative glycosyl hydrolase domain
KPFMNBKC_00475 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KPFMNBKC_00476 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KPFMNBKC_00477 9.5e-110 yjbE P Integral membrane protein TerC family
KPFMNBKC_00478 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KPFMNBKC_00479 3.3e-222 yjbF S Competence protein
KPFMNBKC_00480 0.0 pepF E oligoendopeptidase F
KPFMNBKC_00481 5.8e-19
KPFMNBKC_00482 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KPFMNBKC_00483 4.8e-72 yjbI S Bacterial-like globin
KPFMNBKC_00484 1.9e-116 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KPFMNBKC_00485 2.3e-99 yjbK S protein conserved in bacteria
KPFMNBKC_00486 8.6e-60 yjbL S Belongs to the UPF0738 family
KPFMNBKC_00487 2.3e-108 yjbM 2.7.6.5 S GTP pyrophosphokinase
KPFMNBKC_00488 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KPFMNBKC_00489 6.3e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KPFMNBKC_00490 8.8e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KPFMNBKC_00491 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KPFMNBKC_00492 1.9e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KPFMNBKC_00493 1.2e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
KPFMNBKC_00494 2.7e-213 thiO 1.4.3.19 E Glycine oxidase
KPFMNBKC_00495 6.7e-30 thiS H Thiamine biosynthesis
KPFMNBKC_00496 5.8e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KPFMNBKC_00497 8.4e-190 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KPFMNBKC_00498 3.7e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KPFMNBKC_00499 8.8e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KPFMNBKC_00500 5e-89 yjbX S Spore coat protein
KPFMNBKC_00501 6.7e-83 cotZ S Spore coat protein
KPFMNBKC_00502 9.2e-94 cotY S Spore coat protein Z
KPFMNBKC_00503 4.4e-75 cotX S Spore Coat Protein X and V domain
KPFMNBKC_00504 1.1e-23 cotW
KPFMNBKC_00505 4.2e-57 cotV S Spore Coat Protein X and V domain
KPFMNBKC_00506 7.3e-56 yjcA S Protein of unknown function (DUF1360)
KPFMNBKC_00510 3.8e-38 spoVIF S Stage VI sporulation protein F
KPFMNBKC_00511 0.0 yjcD 3.6.4.12 L DNA helicase
KPFMNBKC_00512 1.8e-35
KPFMNBKC_00513 5.2e-144 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
KPFMNBKC_00514 9.8e-124 S ABC-2 type transporter
KPFMNBKC_00515 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
KPFMNBKC_00516 9.4e-36 K SpoVT / AbrB like domain
KPFMNBKC_00517 3.2e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KPFMNBKC_00518 2.4e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KPFMNBKC_00519 7.2e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
KPFMNBKC_00520 1.4e-209 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KPFMNBKC_00521 3e-215 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KPFMNBKC_00525 3.7e-182 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KPFMNBKC_00526 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KPFMNBKC_00527 3.8e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KPFMNBKC_00528 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KPFMNBKC_00529 1.5e-189 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KPFMNBKC_00530 0.0 ydiF S ABC transporter
KPFMNBKC_00531 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KPFMNBKC_00532 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KPFMNBKC_00533 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KPFMNBKC_00534 1.8e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KPFMNBKC_00535 1.7e-27 ydiK S Domain of unknown function (DUF4305)
KPFMNBKC_00536 5.6e-127 ydiL S CAAX protease self-immunity
KPFMNBKC_00537 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KPFMNBKC_00538 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KPFMNBKC_00539 9.1e-14
KPFMNBKC_00540 7.2e-167 2.1.1.72 L DNA methylase
KPFMNBKC_00541 1.2e-145 3.1.21.5 KL Type III restriction enzyme res subunit
KPFMNBKC_00542 7.6e-151 ydjC S Abhydrolase domain containing 18
KPFMNBKC_00543 0.0 K NB-ARC domain
KPFMNBKC_00544 2.1e-199 gutB 1.1.1.14 E Dehydrogenase
KPFMNBKC_00545 2e-250 gutA G MFS/sugar transport protein
KPFMNBKC_00546 8.9e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
KPFMNBKC_00547 2.3e-29 yjdJ S Domain of unknown function (DUF4306)
KPFMNBKC_00548 1.8e-114 pspA KT Phage shock protein A
KPFMNBKC_00549 2.6e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KPFMNBKC_00550 1.3e-121 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
KPFMNBKC_00551 3.9e-155 ydjI S virion core protein (lumpy skin disease virus)
KPFMNBKC_00552 0.0 yrhL I Acyltransferase family
KPFMNBKC_00553 4.5e-144 rsiV S Protein of unknown function (DUF3298)
KPFMNBKC_00554 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KPFMNBKC_00555 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KPFMNBKC_00556 1.4e-62 ydjM M Lytic transglycolase
KPFMNBKC_00557 3.4e-133 ydjN U Involved in the tonB-independent uptake of proteins
KPFMNBKC_00559 7.2e-35 ydjO S Cold-inducible protein YdjO
KPFMNBKC_00560 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KPFMNBKC_00561 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KPFMNBKC_00562 9.3e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPFMNBKC_00563 1.3e-176 yeaC S COG0714 MoxR-like ATPases
KPFMNBKC_00564 3e-215 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KPFMNBKC_00565 0.0 yebA E COG1305 Transglutaminase-like enzymes
KPFMNBKC_00566 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KPFMNBKC_00567 1.3e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KPFMNBKC_00568 2.1e-247 S Domain of unknown function (DUF4179)
KPFMNBKC_00569 1.4e-208 pbuG S permease
KPFMNBKC_00570 1.6e-124 yebC M Membrane
KPFMNBKC_00572 3.1e-93 yebE S UPF0316 protein
KPFMNBKC_00573 6.1e-28 yebG S NETI protein
KPFMNBKC_00574 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KPFMNBKC_00575 3.6e-224 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KPFMNBKC_00576 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KPFMNBKC_00577 4.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KPFMNBKC_00578 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPFMNBKC_00579 9.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPFMNBKC_00580 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPFMNBKC_00581 2.1e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KPFMNBKC_00582 8.7e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KPFMNBKC_00583 1.8e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KPFMNBKC_00584 1.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KPFMNBKC_00585 5.3e-234 purD 6.3.4.13 F Belongs to the GARS family
KPFMNBKC_00586 1.2e-25 S Protein of unknown function (DUF2892)
KPFMNBKC_00587 0.0 yerA 3.5.4.2 F adenine deaminase
KPFMNBKC_00588 2e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
KPFMNBKC_00589 6.9e-50 yerC S protein conserved in bacteria
KPFMNBKC_00590 1.7e-301 yerD 1.4.7.1 E Belongs to the glutamate synthase family
KPFMNBKC_00591 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KPFMNBKC_00592 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KPFMNBKC_00593 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KPFMNBKC_00594 3.1e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
KPFMNBKC_00595 1.3e-195 yerI S homoserine kinase type II (protein kinase fold)
KPFMNBKC_00596 1.3e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KPFMNBKC_00597 4e-77 ydaG 1.4.3.5 S general stress protein
KPFMNBKC_00598 1e-105 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KPFMNBKC_00599 1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
KPFMNBKC_00600 4.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KPFMNBKC_00601 4.8e-290 ydaB IQ acyl-CoA ligase
KPFMNBKC_00602 0.0 mtlR K transcriptional regulator, MtlR
KPFMNBKC_00603 7.5e-174 ydhF S Oxidoreductase
KPFMNBKC_00604 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KPFMNBKC_00605 1.1e-55 yczJ S biosynthesis
KPFMNBKC_00607 1.2e-117 ycsK E anatomical structure formation involved in morphogenesis
KPFMNBKC_00608 1.3e-129 kipR K Transcriptional regulator
KPFMNBKC_00609 4.2e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KPFMNBKC_00610 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
KPFMNBKC_00611 3.5e-151 ycsI S Belongs to the D-glutamate cyclase family
KPFMNBKC_00612 1.4e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
KPFMNBKC_00613 6e-140 ycsF S Belongs to the UPF0271 (lamB) family
KPFMNBKC_00614 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KPFMNBKC_00616 5.1e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KPFMNBKC_00617 4.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
KPFMNBKC_00618 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KPFMNBKC_00619 2.3e-225 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
KPFMNBKC_00620 6e-55
KPFMNBKC_00621 1.6e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
KPFMNBKC_00622 1e-298 ycnJ P protein, homolog of Cu resistance protein CopC
KPFMNBKC_00623 7.8e-98 ycnI S protein conserved in bacteria
KPFMNBKC_00624 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KPFMNBKC_00625 3.6e-149 glcU U Glucose uptake
KPFMNBKC_00626 5.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KPFMNBKC_00627 1.6e-220 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KPFMNBKC_00628 6.1e-263 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KPFMNBKC_00629 3.3e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
KPFMNBKC_00630 6.1e-45 ycnE S Monooxygenase
KPFMNBKC_00631 5.2e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
KPFMNBKC_00632 1.6e-152 ycnC K Transcriptional regulator
KPFMNBKC_00633 3.6e-247 ycnB EGP Major facilitator Superfamily
KPFMNBKC_00634 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KPFMNBKC_00635 8.1e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KPFMNBKC_00636 1.1e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPFMNBKC_00637 6.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPFMNBKC_00638 1.9e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
KPFMNBKC_00640 1.5e-81 S aspartate phosphatase
KPFMNBKC_00641 1.5e-261 T PhoQ Sensor
KPFMNBKC_00642 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPFMNBKC_00643 3.8e-236 yclI V ABC transporter (permease) YclI
KPFMNBKC_00644 4.3e-121 yclH P ABC transporter
KPFMNBKC_00645 1.5e-250 yxeQ S MmgE/PrpD family
KPFMNBKC_00646 6.4e-218 yxeP 3.5.1.47 E hydrolase activity
KPFMNBKC_00647 1e-131 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
KPFMNBKC_00648 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
KPFMNBKC_00649 1.8e-142 yxeM M Belongs to the bacterial solute-binding protein 3 family
KPFMNBKC_00650 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KPFMNBKC_00651 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPFMNBKC_00652 1.1e-195 gerKB F Spore germination protein
KPFMNBKC_00653 2.1e-235 gerKC S spore germination
KPFMNBKC_00654 5e-285 gerKA EG Spore germination protein
KPFMNBKC_00656 9.8e-279 yclG M Pectate lyase superfamily protein
KPFMNBKC_00657 5.4e-270 dtpT E amino acid peptide transporter
KPFMNBKC_00658 7.5e-77 ctsR K Belongs to the CtsR family
KPFMNBKC_00659 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KPFMNBKC_00660 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KPFMNBKC_00661 0.0 clpC O Belongs to the ClpA ClpB family
KPFMNBKC_00662 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KPFMNBKC_00663 6.4e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KPFMNBKC_00664 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KPFMNBKC_00665 9.4e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KPFMNBKC_00666 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KPFMNBKC_00667 1.1e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KPFMNBKC_00668 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
KPFMNBKC_00669 4e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPFMNBKC_00670 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KPFMNBKC_00671 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPFMNBKC_00672 4.2e-89 yacP S RNA-binding protein containing a PIN domain
KPFMNBKC_00673 8.9e-116 sigH K Belongs to the sigma-70 factor family
KPFMNBKC_00674 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KPFMNBKC_00675 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
KPFMNBKC_00676 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KPFMNBKC_00677 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KPFMNBKC_00678 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KPFMNBKC_00679 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KPFMNBKC_00680 5.3e-107 rsmC 2.1.1.172 J Methyltransferase
KPFMNBKC_00681 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPFMNBKC_00682 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPFMNBKC_00683 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
KPFMNBKC_00684 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KPFMNBKC_00685 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KPFMNBKC_00686 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KPFMNBKC_00687 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KPFMNBKC_00688 2.2e-187 ybaC 3.4.11.5 S Alpha/beta hydrolase family
KPFMNBKC_00689 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KPFMNBKC_00690 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KPFMNBKC_00691 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
KPFMNBKC_00692 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KPFMNBKC_00693 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KPFMNBKC_00694 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KPFMNBKC_00695 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KPFMNBKC_00696 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KPFMNBKC_00697 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KPFMNBKC_00698 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KPFMNBKC_00699 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KPFMNBKC_00700 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KPFMNBKC_00701 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KPFMNBKC_00702 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KPFMNBKC_00703 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KPFMNBKC_00704 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KPFMNBKC_00705 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KPFMNBKC_00706 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KPFMNBKC_00707 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KPFMNBKC_00708 1.9e-23 rpmD J Ribosomal protein L30
KPFMNBKC_00709 4.1e-72 rplO J binds to the 23S rRNA
KPFMNBKC_00710 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KPFMNBKC_00711 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KPFMNBKC_00712 6.3e-142 map 3.4.11.18 E Methionine aminopeptidase
KPFMNBKC_00713 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KPFMNBKC_00714 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KPFMNBKC_00715 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KPFMNBKC_00716 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KPFMNBKC_00717 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPFMNBKC_00718 4.7e-58 rplQ J Ribosomal protein L17
KPFMNBKC_00719 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPFMNBKC_00720 5.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPFMNBKC_00721 2.2e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPFMNBKC_00722 1.1e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KPFMNBKC_00723 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KPFMNBKC_00724 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KPFMNBKC_00725 8.2e-145 ybaJ Q Methyltransferase domain
KPFMNBKC_00726 2.7e-82 yizA S Damage-inducible protein DinB
KPFMNBKC_00727 4.5e-79 ybaK S Protein of unknown function (DUF2521)
KPFMNBKC_00728 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KPFMNBKC_00729 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KPFMNBKC_00730 1.7e-75 gerD
KPFMNBKC_00731 1e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KPFMNBKC_00732 1.9e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
KPFMNBKC_00733 2.2e-30 csfB S Inhibitor of sigma-G Gin
KPFMNBKC_00734 6.6e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KPFMNBKC_00735 5.5e-190 yaaN P Belongs to the TelA family
KPFMNBKC_00736 4e-270 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KPFMNBKC_00737 1.5e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KPFMNBKC_00738 7.5e-55 yaaQ S protein conserved in bacteria
KPFMNBKC_00739 1.2e-71 yaaR S protein conserved in bacteria
KPFMNBKC_00740 8.2e-182 holB 2.7.7.7 L DNA polymerase III
KPFMNBKC_00741 8.8e-145 yaaT S stage 0 sporulation protein
KPFMNBKC_00742 7.7e-37 yabA L Involved in initiation control of chromosome replication
KPFMNBKC_00743 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
KPFMNBKC_00744 1.4e-47 yazA L endonuclease containing a URI domain
KPFMNBKC_00745 1.8e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KPFMNBKC_00746 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
KPFMNBKC_00747 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPFMNBKC_00748 6.9e-144 tatD L hydrolase, TatD
KPFMNBKC_00749 9.1e-232 rpfB GH23 T protein conserved in bacteria
KPFMNBKC_00750 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KPFMNBKC_00751 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KPFMNBKC_00752 1.9e-145 yabG S peptidase
KPFMNBKC_00753 2.3e-38 veg S protein conserved in bacteria
KPFMNBKC_00754 2.9e-27 sspF S DNA topological change
KPFMNBKC_00755 4.6e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KPFMNBKC_00756 5.5e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KPFMNBKC_00757 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KPFMNBKC_00758 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KPFMNBKC_00759 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KPFMNBKC_00760 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPFMNBKC_00761 1.7e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KPFMNBKC_00762 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KPFMNBKC_00763 3.7e-40 yabK S Peptide ABC transporter permease
KPFMNBKC_00764 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KPFMNBKC_00765 6.2e-91 spoVT K stage V sporulation protein
KPFMNBKC_00766 5.4e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KPFMNBKC_00767 4.5e-277 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KPFMNBKC_00768 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KPFMNBKC_00769 1.9e-49 yabP S Sporulation protein YabP
KPFMNBKC_00770 3.8e-103 yabQ S spore cortex biosynthesis protein
KPFMNBKC_00771 2.3e-52 divIC D Septum formation initiator
KPFMNBKC_00772 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KPFMNBKC_00775 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KPFMNBKC_00776 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
KPFMNBKC_00777 6.2e-185 KLT serine threonine protein kinase
KPFMNBKC_00778 4.4e-269 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KPFMNBKC_00779 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KPFMNBKC_00780 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KPFMNBKC_00781 7.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KPFMNBKC_00782 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KPFMNBKC_00783 3.5e-155 yacD 5.2.1.8 O peptidyl-prolyl isomerase
KPFMNBKC_00784 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KPFMNBKC_00785 8.9e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KPFMNBKC_00786 2.3e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KPFMNBKC_00787 3.8e-162 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
KPFMNBKC_00788 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KPFMNBKC_00789 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KPFMNBKC_00790 8.4e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KPFMNBKC_00791 5.9e-29 yazB K transcriptional
KPFMNBKC_00792 1.2e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPFMNBKC_00793 1.9e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KPFMNBKC_00794 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KPFMNBKC_00795 4.9e-125 yhcW 5.4.2.6 S hydrolase
KPFMNBKC_00796 2.6e-68 yhcV S COG0517 FOG CBS domain
KPFMNBKC_00797 1.3e-69 yhcU S Family of unknown function (DUF5365)
KPFMNBKC_00798 1.8e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KPFMNBKC_00799 4.4e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KPFMNBKC_00800 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
KPFMNBKC_00801 3.4e-115 yhcQ M Spore coat protein
KPFMNBKC_00802 2.1e-160 yhcP
KPFMNBKC_00803 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KPFMNBKC_00804 1.2e-48 yhcM
KPFMNBKC_00805 1.6e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KPFMNBKC_00806 3e-185 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
KPFMNBKC_00807 2.3e-145 metQ M Belongs to the nlpA lipoprotein family
KPFMNBKC_00808 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
KPFMNBKC_00809 1.1e-162 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KPFMNBKC_00810 3.4e-166 yhcH V ABC transporter, ATP-binding protein
KPFMNBKC_00811 6.1e-126 yhcG V ABC transporter, ATP-binding protein
KPFMNBKC_00812 2.5e-62 yhcF K Transcriptional regulator
KPFMNBKC_00813 1.3e-52
KPFMNBKC_00814 3.8e-55 yhcC
KPFMNBKC_00815 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
KPFMNBKC_00816 6.4e-285 yhcA EGP Major facilitator Superfamily
KPFMNBKC_00817 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
KPFMNBKC_00818 4.6e-74 yhbI K DNA-binding transcription factor activity
KPFMNBKC_00819 2.7e-216 yhbH S Belongs to the UPF0229 family
KPFMNBKC_00820 0.0 prkA T Ser protein kinase
KPFMNBKC_00822 6.5e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
KPFMNBKC_00823 8.6e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KPFMNBKC_00824 3.9e-108 yhbD K Protein of unknown function (DUF4004)
KPFMNBKC_00825 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KPFMNBKC_00826 4.8e-176 yhbB S Putative amidase domain
KPFMNBKC_00827 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KPFMNBKC_00828 1.5e-112 yhzB S B3/4 domain
KPFMNBKC_00830 4.8e-23 K Transcriptional regulator
KPFMNBKC_00831 1.1e-80 ygaO
KPFMNBKC_00832 1.6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KPFMNBKC_00833 4.2e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KPFMNBKC_00834 8.3e-143 ssuC P ABC transporter (permease)
KPFMNBKC_00835 2e-180 ssuA M Sulfonate ABC transporter
KPFMNBKC_00836 4.6e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KPFMNBKC_00837 1e-185 S Amidohydrolase
KPFMNBKC_00838 3.9e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KPFMNBKC_00839 4.8e-134 oppF3 E Belongs to the ABC transporter superfamily
KPFMNBKC_00840 5.8e-135 oppD3 P Belongs to the ABC transporter superfamily
KPFMNBKC_00841 1.7e-125 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPFMNBKC_00842 3.1e-141 appB P Binding-protein-dependent transport system inner membrane component
KPFMNBKC_00843 4.9e-230 oppA5 E PFAM extracellular solute-binding protein family 5
KPFMNBKC_00845 2e-263 ygaK C Berberine and berberine like
KPFMNBKC_00846 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KPFMNBKC_00847 8.5e-50 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
KPFMNBKC_00848 1.1e-68 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
KPFMNBKC_00849 7e-284 C Na+/H+ antiporter family
KPFMNBKC_00853 1.6e-08
KPFMNBKC_00863 1.1e-75 tspO T membrane
KPFMNBKC_00864 1.7e-131 dksA T COG1734 DnaK suppressor protein
KPFMNBKC_00865 2.7e-271 menF 5.4.4.2 HQ Isochorismate synthase
KPFMNBKC_00866 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KPFMNBKC_00867 6.5e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KPFMNBKC_00868 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KPFMNBKC_00869 1.1e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KPFMNBKC_00870 9.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KPFMNBKC_00871 2.3e-24 S Domain of Unknown Function (DUF1540)
KPFMNBKC_00872 2e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KPFMNBKC_00873 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
KPFMNBKC_00874 1.6e-41 rpmE2 J Ribosomal protein L31
KPFMNBKC_00875 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KPFMNBKC_00876 8.9e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KPFMNBKC_00877 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KPFMNBKC_00878 3.6e-76 ytkA S YtkA-like
KPFMNBKC_00880 1.6e-76 dps P Belongs to the Dps family
KPFMNBKC_00881 1.7e-61 ytkC S Bacteriophage holin family
KPFMNBKC_00882 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KPFMNBKC_00883 5.8e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KPFMNBKC_00884 8.3e-145 ytlC P ABC transporter
KPFMNBKC_00885 9.6e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KPFMNBKC_00886 1.5e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KPFMNBKC_00887 1.6e-38 ytmB S Protein of unknown function (DUF2584)
KPFMNBKC_00888 3.7e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KPFMNBKC_00889 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KPFMNBKC_00890 0.0 asnB 6.3.5.4 E Asparagine synthase
KPFMNBKC_00891 3.7e-260 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
KPFMNBKC_00892 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KPFMNBKC_00893 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
KPFMNBKC_00894 2.9e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KPFMNBKC_00895 1.1e-144 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
KPFMNBKC_00897 1.9e-106 ytqB J Putative rRNA methylase
KPFMNBKC_00898 2.1e-190 yhcC S Fe-S oxidoreductase
KPFMNBKC_00899 1.1e-284 norB EGP COG0477 Permeases of the major facilitator superfamily
KPFMNBKC_00900 1.9e-132 nrsA Q Thioesterase domain
KPFMNBKC_00901 3.1e-189 C Nitroreductase
KPFMNBKC_00902 4.5e-28 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_00903 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
KPFMNBKC_00904 3.4e-110 ywbG M effector of murein hydrolase
KPFMNBKC_00905 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KPFMNBKC_00906 8.2e-152 ywbI K Transcriptional regulator
KPFMNBKC_00907 4.8e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KPFMNBKC_00908 5.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KPFMNBKC_00909 3.7e-243 ywbN P Dyp-type peroxidase family protein
KPFMNBKC_00910 1.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KPFMNBKC_00911 7.7e-131 S Streptomycin biosynthesis protein StrF
KPFMNBKC_00912 3.6e-128 H Methionine biosynthesis protein MetW
KPFMNBKC_00914 1.9e-112 ywcC K Bacterial regulatory proteins, tetR family
KPFMNBKC_00915 1.7e-61 gtcA S GtrA-like protein
KPFMNBKC_00916 1.6e-157 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KPFMNBKC_00917 3.5e-296 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KPFMNBKC_00918 8.4e-27 ywzA S membrane
KPFMNBKC_00919 1.4e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KPFMNBKC_00920 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KPFMNBKC_00921 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KPFMNBKC_00922 9.9e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KPFMNBKC_00923 1.1e-37 ywcE S Required for proper spore morphogenesis. Important for spore germination
KPFMNBKC_00924 5.3e-79 ysnE K acetyltransferase
KPFMNBKC_00925 2.9e-213 rodA D Belongs to the SEDS family
KPFMNBKC_00926 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KPFMNBKC_00927 2.3e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPFMNBKC_00928 0.0 vpr O Belongs to the peptidase S8 family
KPFMNBKC_00930 8.3e-151 sacT K transcriptional antiterminator
KPFMNBKC_00931 2e-07 sacT K transcriptional antiterminator
KPFMNBKC_00932 3.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KPFMNBKC_00933 3e-281 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
KPFMNBKC_00934 9.7e-20 ywdA
KPFMNBKC_00935 2.3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KPFMNBKC_00936 6.3e-57 pex K Transcriptional regulator PadR-like family
KPFMNBKC_00937 3.4e-88 ywdD
KPFMNBKC_00939 5e-153 ywdF GT2,GT4 S Glycosyltransferase like family 2
KPFMNBKC_00940 1.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KPFMNBKC_00941 4.7e-41 ywdI S Family of unknown function (DUF5327)
KPFMNBKC_00942 1.7e-230 ywdJ F Xanthine uracil
KPFMNBKC_00943 4.2e-46 ywdK S small membrane protein
KPFMNBKC_00944 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KPFMNBKC_00945 1.7e-142 spsA M Spore Coat
KPFMNBKC_00946 1.3e-273 spsB M Capsule polysaccharide biosynthesis protein
KPFMNBKC_00947 1.6e-221 spsC E Belongs to the DegT DnrJ EryC1 family
KPFMNBKC_00948 1.9e-158 spsD 2.3.1.210 K Spore Coat
KPFMNBKC_00949 1.3e-215 spsE 2.5.1.56 M acid synthase
KPFMNBKC_00950 1.4e-133 spsF M Spore Coat
KPFMNBKC_00951 2.4e-184 spsG M Spore Coat
KPFMNBKC_00952 1.2e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KPFMNBKC_00953 6e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KPFMNBKC_00954 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KPFMNBKC_00955 3.5e-87 spsL 5.1.3.13 M Spore Coat
KPFMNBKC_00956 6.7e-173 bcrA5 V ABC transporter, ATP-binding protein
KPFMNBKC_00957 5.1e-117 S ABC-2 family transporter protein
KPFMNBKC_00958 1e-74
KPFMNBKC_00959 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPFMNBKC_00960 6.6e-157 T PhoQ Sensor
KPFMNBKC_00961 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KPFMNBKC_00962 1.2e-293 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KPFMNBKC_00963 0.0 rocB E arginine degradation protein
KPFMNBKC_00964 2.2e-260 lysP E amino acid
KPFMNBKC_00965 4.5e-206 tcaB EGP Major facilitator Superfamily
KPFMNBKC_00966 4.1e-223 ywfA EGP Major facilitator Superfamily
KPFMNBKC_00967 3.3e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KPFMNBKC_00968 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KPFMNBKC_00969 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KPFMNBKC_00970 1.1e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KPFMNBKC_00971 4.7e-208 bacE EGP Major facilitator Superfamily
KPFMNBKC_00972 3.5e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
KPFMNBKC_00973 8.2e-140 IQ Enoyl-(Acyl carrier protein) reductase
KPFMNBKC_00974 1.1e-146 ywfI C May function as heme-dependent peroxidase
KPFMNBKC_00975 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KPFMNBKC_00976 1.1e-157 MA20_14895 S Conserved hypothetical protein 698
KPFMNBKC_00977 2.3e-162 cysL K Transcriptional regulator
KPFMNBKC_00978 2.3e-159 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KPFMNBKC_00980 4.5e-174
KPFMNBKC_00983 1.3e-168 yhcI S ABC transporter (permease)
KPFMNBKC_00984 8.5e-165 V ABC transporter, ATP-binding protein
KPFMNBKC_00985 2e-92 S membrane
KPFMNBKC_00986 7.4e-52 padR K PadR family transcriptional regulator
KPFMNBKC_00987 3e-110 rsfA_1
KPFMNBKC_00988 6.9e-36 ywzC S Belongs to the UPF0741 family
KPFMNBKC_00989 3.9e-256 ywfO S COG1078 HD superfamily phosphohydrolases
KPFMNBKC_00990 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
KPFMNBKC_00991 3e-246 yhdG_1 E C-terminus of AA_permease
KPFMNBKC_00992 8e-70 ywhA K Transcriptional regulator
KPFMNBKC_00993 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KPFMNBKC_00994 1.2e-117 ywhC S Peptidase family M50
KPFMNBKC_00995 1.4e-95 ywhD S YwhD family
KPFMNBKC_00996 5.7e-79
KPFMNBKC_00997 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KPFMNBKC_00998 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KPFMNBKC_00999 3.5e-168 speB 3.5.3.11 E Belongs to the arginase family
KPFMNBKC_01002 5.8e-75 CP Membrane
KPFMNBKC_01004 7.5e-28 S Domain of unknown function (DUF4177)
KPFMNBKC_01005 5e-33
KPFMNBKC_01006 9.7e-29 ydcG K sequence-specific DNA binding
KPFMNBKC_01008 1.4e-76 S aspartate phosphatase
KPFMNBKC_01009 1.3e-209 ywhK CO amine dehydrogenase activity
KPFMNBKC_01010 1.8e-227 ywhL CO amine dehydrogenase activity
KPFMNBKC_01012 8.8e-72 ywiB S protein conserved in bacteria
KPFMNBKC_01013 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KPFMNBKC_01014 2.2e-213 narK P COG2223 Nitrate nitrite transporter
KPFMNBKC_01015 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
KPFMNBKC_01016 1.3e-139 ywiC S YwiC-like protein
KPFMNBKC_01017 2e-85 arfM T cyclic nucleotide binding
KPFMNBKC_01018 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KPFMNBKC_01019 3.4e-293 narH 1.7.5.1 C Nitrate reductase, beta
KPFMNBKC_01020 1.3e-96 narJ 1.7.5.1 C nitrate reductase
KPFMNBKC_01021 1.2e-123 narI 1.7.5.1 C nitrate reductase, gamma
KPFMNBKC_01022 8.9e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPFMNBKC_01023 9.9e-288 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPFMNBKC_01024 0.0 ywjA V ABC transporter
KPFMNBKC_01025 4.2e-43 ywjC
KPFMNBKC_01026 9.2e-178 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KPFMNBKC_01027 9.2e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KPFMNBKC_01028 0.0 fadF C COG0247 Fe-S oxidoreductase
KPFMNBKC_01029 8.3e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KPFMNBKC_01030 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KPFMNBKC_01031 4.2e-92 ywjG S Domain of unknown function (DUF2529)
KPFMNBKC_01032 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
KPFMNBKC_01033 2.1e-157 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KPFMNBKC_01034 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KPFMNBKC_01035 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPFMNBKC_01036 2.1e-174 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KPFMNBKC_01037 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KPFMNBKC_01038 1.1e-32 rpmE J Binds the 23S rRNA
KPFMNBKC_01039 1.4e-104 tdk 2.7.1.21 F thymidine kinase
KPFMNBKC_01040 0.0 sfcA 1.1.1.38 C malic enzyme
KPFMNBKC_01041 3.6e-158 ywkB S Membrane transport protein
KPFMNBKC_01042 4.4e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KPFMNBKC_01043 5.8e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KPFMNBKC_01044 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KPFMNBKC_01045 1.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KPFMNBKC_01046 1.2e-08 ywlA S Uncharacterised protein family (UPF0715)
KPFMNBKC_01047 6.7e-60 ywlA S Uncharacterised protein family (UPF0715)
KPFMNBKC_01048 8.9e-119 spoIIR S stage II sporulation protein R
KPFMNBKC_01049 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
KPFMNBKC_01050 1.1e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KPFMNBKC_01051 4.5e-84 mntP P Probably functions as a manganese efflux pump
KPFMNBKC_01052 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KPFMNBKC_01053 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KPFMNBKC_01054 6.5e-96 ywlG S Belongs to the UPF0340 family
KPFMNBKC_01055 2.5e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KPFMNBKC_01056 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KPFMNBKC_01057 2.1e-61 atpI S ATP synthase
KPFMNBKC_01058 2.1e-129 atpB C it plays a direct role in the translocation of protons across the membrane
KPFMNBKC_01059 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPFMNBKC_01060 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KPFMNBKC_01061 1e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPFMNBKC_01062 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KPFMNBKC_01063 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KPFMNBKC_01064 7e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KPFMNBKC_01065 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KPFMNBKC_01066 2.3e-89 ywmA
KPFMNBKC_01067 1.3e-32 ywzB S membrane
KPFMNBKC_01068 2.2e-134 ywmB S TATA-box binding
KPFMNBKC_01069 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPFMNBKC_01070 3.3e-189 spoIID D Stage II sporulation protein D
KPFMNBKC_01071 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
KPFMNBKC_01072 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
KPFMNBKC_01074 2.2e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KPFMNBKC_01075 5.9e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KPFMNBKC_01076 1.9e-94 S response regulator aspartate phosphatase
KPFMNBKC_01077 3.6e-82 ywmF S Peptidase M50
KPFMNBKC_01078 7.4e-10 csbD K CsbD-like
KPFMNBKC_01079 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KPFMNBKC_01080 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KPFMNBKC_01081 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KPFMNBKC_01082 2.1e-67 ywnA K Transcriptional regulator
KPFMNBKC_01083 1.7e-119 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
KPFMNBKC_01084 2.8e-53 ywnC S Family of unknown function (DUF5362)
KPFMNBKC_01085 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPFMNBKC_01086 2.7e-68 ywnF S Family of unknown function (DUF5392)
KPFMNBKC_01087 1.2e-10 ywnC S Family of unknown function (DUF5362)
KPFMNBKC_01088 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KPFMNBKC_01089 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KPFMNBKC_01090 1.1e-71 ywnJ S VanZ like family
KPFMNBKC_01091 3.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KPFMNBKC_01092 4.9e-210 ftsW D Belongs to the SEDS family
KPFMNBKC_01093 2e-58 nrgB K Belongs to the P(II) protein family
KPFMNBKC_01094 7.1e-228 amt P Ammonium transporter
KPFMNBKC_01095 2.4e-101 phzA Q Isochorismatase family
KPFMNBKC_01096 3.6e-244 ywoD EGP Major facilitator superfamily
KPFMNBKC_01097 2.1e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
KPFMNBKC_01098 1.1e-212 ywoG EGP Major facilitator Superfamily
KPFMNBKC_01099 8.5e-72 ywoH K transcriptional
KPFMNBKC_01100 1.8e-44 spoIIID K Stage III sporulation protein D
KPFMNBKC_01101 2.7e-180 mbl D Rod shape-determining protein
KPFMNBKC_01102 3.2e-128 flhO N flagellar basal body
KPFMNBKC_01103 5.3e-142 flhP N flagellar basal body
KPFMNBKC_01104 4.7e-199 S aspartate phosphatase
KPFMNBKC_01105 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KPFMNBKC_01106 9e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KPFMNBKC_01107 3.9e-69 ywpF S YwpF-like protein
KPFMNBKC_01108 4e-62 ywpG
KPFMNBKC_01109 7.5e-58 ssbB L Single-stranded DNA-binding protein
KPFMNBKC_01110 8.9e-137 glcR K DeoR C terminal sensor domain
KPFMNBKC_01111 2.3e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
KPFMNBKC_01112 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KPFMNBKC_01113 6e-307 ywqB S SWIM zinc finger
KPFMNBKC_01114 1.3e-14
KPFMNBKC_01115 1.7e-110 ywqC M biosynthesis protein
KPFMNBKC_01116 4.8e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KPFMNBKC_01117 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KPFMNBKC_01118 3.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KPFMNBKC_01119 1e-150 ywqG S Domain of unknown function (DUF1963)
KPFMNBKC_01121 1.1e-21 S Domain of unknown function (DUF5082)
KPFMNBKC_01122 3.6e-36 ywqI S Family of unknown function (DUF5344)
KPFMNBKC_01123 1.4e-257 ywqJ S Pre-toxin TG
KPFMNBKC_01124 1e-63
KPFMNBKC_01125 1.1e-94
KPFMNBKC_01126 6.5e-136 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KPFMNBKC_01127 3.8e-88 ywrA P COG2059 Chromate transport protein ChrA
KPFMNBKC_01128 2.3e-102 ywrB P Chromate transporter
KPFMNBKC_01129 1.1e-83 ywrC K Transcriptional regulator
KPFMNBKC_01130 1.4e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KPFMNBKC_01131 8e-07 S Domain of unknown function (DUF4181)
KPFMNBKC_01132 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KPFMNBKC_01133 2e-09
KPFMNBKC_01134 1e-212 cotH M Spore Coat
KPFMNBKC_01135 7e-132 cotB
KPFMNBKC_01136 4.4e-126 ywrJ
KPFMNBKC_01137 2.1e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KPFMNBKC_01138 9e-167 alsR K LysR substrate binding domain
KPFMNBKC_01139 1.2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KPFMNBKC_01140 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KPFMNBKC_01141 2.9e-96 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
KPFMNBKC_01142 1.5e-89 batE T Sh3 type 3 domain protein
KPFMNBKC_01143 5.7e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KPFMNBKC_01144 1.9e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
KPFMNBKC_01145 4.2e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KPFMNBKC_01146 4.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KPFMNBKC_01147 3e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KPFMNBKC_01148 4.2e-178 rbsR K transcriptional
KPFMNBKC_01149 4.8e-202 gerKC S Spore germination B3/ GerAC like, C-terminal
KPFMNBKC_01150 1.5e-192 gerKB E Spore germination protein
KPFMNBKC_01151 1.2e-197 gerKA EG Spore germination protein
KPFMNBKC_01152 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
KPFMNBKC_01153 2.3e-70 pgsC S biosynthesis protein
KPFMNBKC_01154 1.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KPFMNBKC_01155 1.1e-19 ywtC
KPFMNBKC_01156 8.3e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KPFMNBKC_01157 2.6e-36 yttA 2.7.13.3 S Pfam Transposase IS66
KPFMNBKC_01158 1e-156 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
KPFMNBKC_01159 1.9e-178 ywtF K Transcriptional regulator
KPFMNBKC_01160 3.2e-248 ywtG EGP Major facilitator Superfamily
KPFMNBKC_01161 1.6e-263 GT2,GT4 J Glycosyl transferase family 2
KPFMNBKC_01162 7.9e-213 gerAC S Spore germination protein
KPFMNBKC_01163 6.4e-199 gerBB E Spore germination protein
KPFMNBKC_01164 4.6e-266 gerBA EG Spore germination protein
KPFMNBKC_01165 6.7e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
KPFMNBKC_01166 8.3e-229 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KPFMNBKC_01167 1.2e-219 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KPFMNBKC_01168 2.6e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KPFMNBKC_01169 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KPFMNBKC_01170 1.2e-288 M Glycosyltransferase like family 2
KPFMNBKC_01171 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KPFMNBKC_01172 2.8e-151 tagG GM Transport permease protein
KPFMNBKC_01173 6.4e-282 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KPFMNBKC_01174 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KPFMNBKC_01175 2e-211 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KPFMNBKC_01176 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KPFMNBKC_01177 1.7e-48
KPFMNBKC_01178 0.0 lytB 3.5.1.28 D Stage II sporulation protein
KPFMNBKC_01179 1e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KPFMNBKC_01180 4e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KPFMNBKC_01181 1.1e-256 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KPFMNBKC_01182 1.4e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
KPFMNBKC_01183 1.5e-250 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KPFMNBKC_01184 5e-257 tuaE M Teichuronic acid biosynthesis protein
KPFMNBKC_01185 4.6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
KPFMNBKC_01186 5.8e-143 tuaG GT2 M Glycosyltransferase like family 2
KPFMNBKC_01187 2.6e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
KPFMNBKC_01188 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KPFMNBKC_01189 1.5e-172 yvhJ K Transcriptional regulator
KPFMNBKC_01190 2.2e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KPFMNBKC_01191 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KPFMNBKC_01192 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KPFMNBKC_01193 1.4e-158 degV S protein conserved in bacteria
KPFMNBKC_01194 2.7e-255 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KPFMNBKC_01195 1.7e-42 comFB S Late competence development protein ComFB
KPFMNBKC_01196 4.1e-78 comFC S Phosphoribosyl transferase domain
KPFMNBKC_01197 1.4e-74 yvyF S flagellar protein
KPFMNBKC_01198 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
KPFMNBKC_01199 7.6e-80 flgN NOU FlgN protein
KPFMNBKC_01200 1.1e-273 flgK N flagellar hook-associated protein
KPFMNBKC_01201 2.3e-162 flgL N Belongs to the bacterial flagellin family
KPFMNBKC_01202 1.4e-80 yviE
KPFMNBKC_01203 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KPFMNBKC_01204 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KPFMNBKC_01205 2.1e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KPFMNBKC_01206 4.8e-261 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KPFMNBKC_01207 8.8e-66 fliS N flagellar protein FliS
KPFMNBKC_01208 4.1e-11 fliT S bacterial-type flagellum organization
KPFMNBKC_01209 6.8e-68
KPFMNBKC_01210 4.8e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KPFMNBKC_01211 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KPFMNBKC_01212 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KPFMNBKC_01213 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KPFMNBKC_01214 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
KPFMNBKC_01215 1e-122 ftsE D cell division ATP-binding protein FtsE
KPFMNBKC_01216 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KPFMNBKC_01217 2.6e-46 L Molecular Function DNA binding, Biological Process DNA recombination
KPFMNBKC_01218 2.8e-41 L transposase activity
KPFMNBKC_01219 2.9e-225 ywoF P Right handed beta helix region
KPFMNBKC_01220 3.2e-256 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KPFMNBKC_01221 1.5e-55 swrA S Swarming motility protein
KPFMNBKC_01222 9.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KPFMNBKC_01223 1e-183 S Psort location CytoplasmicMembrane, score
KPFMNBKC_01225 1.7e-26 bacT Q Thioesterase domain
KPFMNBKC_01226 3e-227 yvkA EGP Major facilitator Superfamily
KPFMNBKC_01227 2.4e-110 yvkB K Transcriptional regulator
KPFMNBKC_01228 0.0 yvkC 2.7.9.2 GT Phosphotransferase
KPFMNBKC_01229 7.6e-33 csbA S protein conserved in bacteria
KPFMNBKC_01230 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KPFMNBKC_01231 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KPFMNBKC_01232 1.5e-37 yvkN
KPFMNBKC_01233 4e-48 yvlA
KPFMNBKC_01234 3.2e-166 yvlB S Putative adhesin
KPFMNBKC_01235 9.6e-26 pspB KT PspC domain
KPFMNBKC_01236 3.9e-41 yvlD S Membrane
KPFMNBKC_01237 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
KPFMNBKC_01238 8.1e-105 yxaF K Transcriptional regulator
KPFMNBKC_01239 1.5e-132 yvoA K transcriptional
KPFMNBKC_01240 6.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KPFMNBKC_01241 6.1e-224 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KPFMNBKC_01242 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KPFMNBKC_01243 1.4e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KPFMNBKC_01244 1.1e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KPFMNBKC_01245 4.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KPFMNBKC_01246 1.8e-138 yvpB NU protein conserved in bacteria
KPFMNBKC_01247 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KPFMNBKC_01248 1.3e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KPFMNBKC_01249 2.1e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KPFMNBKC_01250 2e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KPFMNBKC_01251 9.6e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KPFMNBKC_01252 2.2e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KPFMNBKC_01253 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KPFMNBKC_01254 2.1e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KPFMNBKC_01255 0.0 msbA2 3.6.3.44 V ABC transporter
KPFMNBKC_01256 1.2e-120 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPFMNBKC_01257 1.4e-190 sasA T Histidine kinase
KPFMNBKC_01258 4.2e-275 S COG0457 FOG TPR repeat
KPFMNBKC_01259 1.3e-124 usp CBM50 M protein conserved in bacteria
KPFMNBKC_01260 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KPFMNBKC_01261 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KPFMNBKC_01262 1.1e-166 rapZ S Displays ATPase and GTPase activities
KPFMNBKC_01263 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KPFMNBKC_01264 3.1e-170 whiA K May be required for sporulation
KPFMNBKC_01265 4.7e-36 crh G Phosphocarrier protein Chr
KPFMNBKC_01266 1.3e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
KPFMNBKC_01267 4.6e-79 M Ribonuclease
KPFMNBKC_01268 5e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPFMNBKC_01269 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KPFMNBKC_01270 9.5e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
KPFMNBKC_01271 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
KPFMNBKC_01272 2.1e-105 yvdD 3.2.2.10 S Belongs to the LOG family
KPFMNBKC_01273 3.4e-250 EGP Sugar (and other) transporter
KPFMNBKC_01274 5.5e-214 yraM S PrpF protein
KPFMNBKC_01275 6.7e-164 yraN K Transcriptional regulator
KPFMNBKC_01276 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KPFMNBKC_01277 1.3e-184 scrR K transcriptional
KPFMNBKC_01278 8e-219 rafB P LacY proton/sugar symporter
KPFMNBKC_01279 8.2e-295 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
KPFMNBKC_01281 3.1e-34
KPFMNBKC_01282 1.2e-236 I Pfam Lipase (class 3)
KPFMNBKC_01283 1.3e-15 S Protein of unknown function (DUF1433)
KPFMNBKC_01284 3.2e-25 S Protein of unknown function (DUF1433)
KPFMNBKC_01285 1.2e-39 I Pfam Lipase (class 3)
KPFMNBKC_01286 6.5e-38 S Protein of unknown function (DUF1433)
KPFMNBKC_01287 7e-17 S Protein of unknown function (DUF1433)
KPFMNBKC_01288 5.5e-94 padC Q Phenolic acid decarboxylase
KPFMNBKC_01289 1.2e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KPFMNBKC_01290 1.3e-111 yyaS S Membrane
KPFMNBKC_01291 5.2e-98 ywjB H RibD C-terminal domain
KPFMNBKC_01293 4.2e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KPFMNBKC_01294 5.1e-78 slr K transcriptional
KPFMNBKC_01295 8.4e-120 ywqC M biosynthesis protein
KPFMNBKC_01296 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
KPFMNBKC_01297 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
KPFMNBKC_01298 1.3e-218 epsD GT4 M Glycosyl transferase 4-like
KPFMNBKC_01299 3.1e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KPFMNBKC_01300 5.5e-214 epsF GT4 M Glycosyl transferases group 1
KPFMNBKC_01301 3.5e-205 epsG S EpsG family
KPFMNBKC_01302 3.4e-194 epsH GT2 S Glycosyltransferase like family 2
KPFMNBKC_01303 5.4e-203 epsI GM pyruvyl transferase
KPFMNBKC_01304 1.8e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KPFMNBKC_01305 7e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KPFMNBKC_01306 1.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KPFMNBKC_01307 1.6e-53 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
KPFMNBKC_01308 9e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KPFMNBKC_01309 6e-185 yvfF GM Exopolysaccharide biosynthesis protein
KPFMNBKC_01310 2.7e-32 yvfG S YvfG protein
KPFMNBKC_01311 9.1e-245 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KPFMNBKC_01312 1.9e-303 yvfH C L-lactate permease
KPFMNBKC_01313 6.6e-120 yvfI K COG2186 Transcriptional regulators
KPFMNBKC_01314 2.9e-221 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KPFMNBKC_01315 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KPFMNBKC_01316 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KPFMNBKC_01317 1.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KPFMNBKC_01318 2.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
KPFMNBKC_01319 2.1e-296 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
KPFMNBKC_01320 5e-151 ybbH_1 K RpiR family transcriptional regulator
KPFMNBKC_01321 5.1e-167 3.1.3.104 S hydrolases of the HAD superfamily
KPFMNBKC_01322 1.3e-114 yyaS S Membrane
KPFMNBKC_01323 4e-181 purR7 5.1.1.1 K Transcriptional regulator
KPFMNBKC_01324 1.9e-258
KPFMNBKC_01325 5e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
KPFMNBKC_01326 1.7e-157 yvbV EG EamA-like transporter family
KPFMNBKC_01327 1.5e-155 yvbU K Transcriptional regulator
KPFMNBKC_01329 3.2e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPFMNBKC_01330 3.2e-203 araR K transcriptional
KPFMNBKC_01331 1.3e-252 araE EGP Major facilitator Superfamily
KPFMNBKC_01333 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KPFMNBKC_01334 4.8e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KPFMNBKC_01335 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KPFMNBKC_01336 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KPFMNBKC_01337 2.8e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KPFMNBKC_01338 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KPFMNBKC_01339 9.8e-236 ywaD 3.4.11.10, 3.4.11.6 S PA domain
KPFMNBKC_01340 1.8e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KPFMNBKC_01341 1.8e-217 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KPFMNBKC_01342 1.4e-170 5.1.3.2 M GDP-mannose 4,6 dehydratase
KPFMNBKC_01343 1.4e-231 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KPFMNBKC_01344 3.5e-147 M Protein involved in cellulose biosynthesis
KPFMNBKC_01345 9.6e-143 C WbqC-like protein family
KPFMNBKC_01346 3.7e-125 S GlcNAc-PI de-N-acetylase
KPFMNBKC_01347 7.9e-179
KPFMNBKC_01348 6e-214 EGP Major facilitator Superfamily
KPFMNBKC_01349 2.5e-80 yvbK 3.1.3.25 K acetyltransferase
KPFMNBKC_01350 0.0 tcaA S response to antibiotic
KPFMNBKC_01351 3.2e-119 exoY M Membrane
KPFMNBKC_01352 5.2e-105 yvbG U UPF0056 membrane protein
KPFMNBKC_01353 7.1e-98 yvbF K Belongs to the GbsR family
KPFMNBKC_01354 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KPFMNBKC_01355 1e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KPFMNBKC_01356 4.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KPFMNBKC_01357 6.3e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KPFMNBKC_01358 4.3e-76 yvbF K Belongs to the GbsR family
KPFMNBKC_01359 6.3e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KPFMNBKC_01360 5.4e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KPFMNBKC_01361 1.7e-173 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KPFMNBKC_01362 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KPFMNBKC_01363 4.6e-126 mutF V ABC transporter, ATP-binding protein
KPFMNBKC_01364 1e-120 spaE S ABC-2 family transporter protein
KPFMNBKC_01365 7.5e-138 mutG S ABC-2 family transporter protein
KPFMNBKC_01366 2e-123 K Transcriptional regulatory protein, C terminal
KPFMNBKC_01367 9.7e-253 T His Kinase A (phosphoacceptor) domain
KPFMNBKC_01368 8.8e-53 yodB K transcriptional
KPFMNBKC_01369 1.1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
KPFMNBKC_01370 1e-69 K transcriptional
KPFMNBKC_01371 6e-35 yvzC K Transcriptional
KPFMNBKC_01372 4.8e-24 secG U Preprotein translocase subunit SecG
KPFMNBKC_01373 7.4e-143 est 3.1.1.1 S Carboxylesterase
KPFMNBKC_01374 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KPFMNBKC_01375 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KPFMNBKC_01377 2.3e-39 yrdF K ribonuclease inhibitor
KPFMNBKC_01378 6.7e-50 yrdF K ribonuclease inhibitor
KPFMNBKC_01379 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KPFMNBKC_01380 2.6e-158 ytlI K LysR substrate binding domain
KPFMNBKC_01381 3e-101 ytmI K Acetyltransferase (GNAT) domain
KPFMNBKC_01382 2.7e-130 ytmJ ET Bacterial periplasmic substrate-binding proteins
KPFMNBKC_01383 1e-145 tcyK M Bacterial periplasmic substrate-binding proteins
KPFMNBKC_01384 7.7e-121 tcyL P Binding-protein-dependent transport system inner membrane component
KPFMNBKC_01385 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
KPFMNBKC_01386 3.6e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KPFMNBKC_01387 6e-180 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPFMNBKC_01388 1.5e-46 ytnI O COG0695 Glutaredoxin and related proteins
KPFMNBKC_01389 1.2e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPFMNBKC_01390 5.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KPFMNBKC_01391 1.4e-192 yvaA 1.1.1.371 S Oxidoreductase
KPFMNBKC_01392 3.7e-48 csoR S transcriptional
KPFMNBKC_01393 9.9e-29 copZ P Heavy-metal-associated domain
KPFMNBKC_01394 0.0 copA 3.6.3.54 P P-type ATPase
KPFMNBKC_01395 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KPFMNBKC_01396 1.2e-102 bdbD O Thioredoxin
KPFMNBKC_01397 1e-72 bdbC O Required for disulfide bond formation in some proteins
KPFMNBKC_01398 5.2e-142 S Metallo-peptidase family M12
KPFMNBKC_01399 3.5e-106 yvgT S membrane
KPFMNBKC_01400 0.0 helD 3.6.4.12 L DNA helicase
KPFMNBKC_01401 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KPFMNBKC_01402 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KPFMNBKC_01403 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KPFMNBKC_01404 5.4e-86 yvgO
KPFMNBKC_01405 5e-156 yvgN S reductase
KPFMNBKC_01406 4.7e-197 yfiN V COG0842 ABC-type multidrug transport system, permease component
KPFMNBKC_01407 6.1e-194 yfiM V ABC-2 type transporter
KPFMNBKC_01408 2.1e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
KPFMNBKC_01409 1.3e-63 T Histidine kinase
KPFMNBKC_01410 1.7e-85 T Histidine kinase
KPFMNBKC_01411 2.8e-114 yfiK K Regulator
KPFMNBKC_01412 1e-98 modB P COG4149 ABC-type molybdate transport system, permease component
KPFMNBKC_01413 3.7e-140 modA P COG0725 ABC-type molybdate transport system, periplasmic component
KPFMNBKC_01414 1.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
KPFMNBKC_01415 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KPFMNBKC_01416 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
KPFMNBKC_01417 3.6e-14 S Small spore protein J (Spore_SspJ)
KPFMNBKC_01418 1.3e-236 yvsH E Arginine ornithine antiporter
KPFMNBKC_01419 2e-177 fhuD P ABC transporter
KPFMNBKC_01420 2.5e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPFMNBKC_01421 4e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPFMNBKC_01422 3.1e-147 fhuC 3.6.3.34 HP ABC transporter
KPFMNBKC_01423 1.9e-42 L COG2963 Transposase and inactivated derivatives
KPFMNBKC_01424 1.2e-124 L Molecular Function DNA binding, Biological Process DNA recombination
KPFMNBKC_01425 1.1e-66 yvrL S Regulatory protein YrvL
KPFMNBKC_01426 3.5e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
KPFMNBKC_01427 1.6e-15 S YvrJ protein family
KPFMNBKC_01428 9.9e-103 yvrI K RNA polymerase
KPFMNBKC_01429 1.1e-36
KPFMNBKC_01430 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPFMNBKC_01431 0.0 T PhoQ Sensor
KPFMNBKC_01432 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
KPFMNBKC_01433 5.3e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KPFMNBKC_01434 1.1e-167 yvrC P ABC transporter substrate-binding protein
KPFMNBKC_01435 8.2e-180 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPFMNBKC_01436 1.1e-223 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KPFMNBKC_01437 5.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
KPFMNBKC_01438 4.8e-227 yvqJ EGP Major facilitator Superfamily
KPFMNBKC_01439 3.3e-46 liaI S membrane
KPFMNBKC_01440 1.1e-92 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KPFMNBKC_01441 4.8e-117 liaG S Putative adhesin
KPFMNBKC_01442 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
KPFMNBKC_01443 2.3e-193 vraS 2.7.13.3 T Histidine kinase
KPFMNBKC_01444 9.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KPFMNBKC_01445 3.1e-201 gerAC S Spore germination B3/ GerAC like, C-terminal
KPFMNBKC_01446 1.1e-187 gerAB E Spore germination protein
KPFMNBKC_01447 1.3e-257 gerAA EG Spore germination protein
KPFMNBKC_01448 6.6e-24 S Protein of unknown function (DUF3970)
KPFMNBKC_01449 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KPFMNBKC_01450 1e-157 yuxN K Transcriptional regulator
KPFMNBKC_01451 1.3e-23
KPFMNBKC_01452 6.7e-251 cssS 2.7.13.3 T PhoQ Sensor
KPFMNBKC_01453 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPFMNBKC_01454 8.5e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KPFMNBKC_01455 3.6e-79 dps P Belongs to the Dps family
KPFMNBKC_01456 4.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KPFMNBKC_01457 0.0 pepF2 E COG1164 Oligoendopeptidase F
KPFMNBKC_01458 2.5e-45 S YusW-like protein
KPFMNBKC_01459 2.4e-150 yusV 3.6.3.34 HP ABC transporter
KPFMNBKC_01460 3.3e-39 yusU S Protein of unknown function (DUF2573)
KPFMNBKC_01461 3.9e-190 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KPFMNBKC_01462 9.4e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
KPFMNBKC_01463 8.8e-159 ywbI2 K Transcriptional regulator
KPFMNBKC_01464 8.1e-288 yusP P Major facilitator superfamily
KPFMNBKC_01465 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
KPFMNBKC_01466 1.1e-53 yusN M Coat F domain
KPFMNBKC_01467 1.4e-43
KPFMNBKC_01468 9e-167 fadM E Proline dehydrogenase
KPFMNBKC_01469 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KPFMNBKC_01470 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
KPFMNBKC_01471 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KPFMNBKC_01472 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KPFMNBKC_01473 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KPFMNBKC_01474 3.7e-40 yusG S Protein of unknown function (DUF2553)
KPFMNBKC_01475 1.4e-62 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
KPFMNBKC_01476 1.6e-54 yusE CO Thioredoxin
KPFMNBKC_01477 5e-57 yusD S SCP-2 sterol transfer family
KPFMNBKC_01478 6.3e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KPFMNBKC_01479 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
KPFMNBKC_01480 2.3e-145 metQ P Belongs to the NlpA lipoprotein family
KPFMNBKC_01481 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KPFMNBKC_01482 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KPFMNBKC_01483 7e-245 sufD O assembly protein SufD
KPFMNBKC_01484 1.4e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KPFMNBKC_01485 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KPFMNBKC_01486 3e-270 sufB O FeS cluster assembly
KPFMNBKC_01487 8.6e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KPFMNBKC_01488 8.5e-81 yncE S Protein of unknown function (DUF2691)
KPFMNBKC_01489 6.3e-128 Q ubiE/COQ5 methyltransferase family
KPFMNBKC_01490 1.9e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KPFMNBKC_01491 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
KPFMNBKC_01493 2.3e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KPFMNBKC_01494 5.5e-225 yurO G COG1653 ABC-type sugar transport system, periplasmic component
KPFMNBKC_01495 1.1e-156 yurN G Binding-protein-dependent transport system inner membrane component
KPFMNBKC_01496 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
KPFMNBKC_01497 2.4e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
KPFMNBKC_01498 3.6e-134 yurK K UTRA
KPFMNBKC_01499 3.1e-206 msmX P Belongs to the ABC transporter superfamily
KPFMNBKC_01500 2.7e-168 bsn L Ribonuclease
KPFMNBKC_01501 1.8e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KPFMNBKC_01502 1.1e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KPFMNBKC_01503 1.7e-213 blt EGP Major facilitator Superfamily
KPFMNBKC_01504 2.8e-69
KPFMNBKC_01505 5.7e-179 S Aspartate phosphatase response regulator
KPFMNBKC_01507 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
KPFMNBKC_01508 5e-262 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KPFMNBKC_01509 9.8e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
KPFMNBKC_01510 8.1e-170 yunF S Protein of unknown function DUF72
KPFMNBKC_01511 3.9e-145 yunE S membrane transporter protein
KPFMNBKC_01512 4.2e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KPFMNBKC_01513 3.6e-129 yunB S Sporulation protein YunB (Spo_YunB)
KPFMNBKC_01514 7.1e-194 lytH M Peptidase, M23
KPFMNBKC_01515 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KPFMNBKC_01516 8.2e-47 yutD S protein conserved in bacteria
KPFMNBKC_01517 2.8e-73 yutE S Protein of unknown function DUF86
KPFMNBKC_01518 1.4e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KPFMNBKC_01519 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KPFMNBKC_01520 3.2e-197 yutH S Spore coat protein
KPFMNBKC_01521 5.1e-240 hom 1.1.1.3 E homoserine dehydrogenase
KPFMNBKC_01522 1.1e-195 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KPFMNBKC_01523 7.5e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KPFMNBKC_01524 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
KPFMNBKC_01525 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
KPFMNBKC_01526 6.7e-56 yuzD S protein conserved in bacteria
KPFMNBKC_01527 4.2e-208 yutJ 1.6.99.3 C NADH dehydrogenase
KPFMNBKC_01528 2.4e-39 yuzB S Belongs to the UPF0349 family
KPFMNBKC_01529 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPFMNBKC_01530 5.7e-163 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KPFMNBKC_01531 1.1e-62 erpA S Belongs to the HesB IscA family
KPFMNBKC_01532 1.6e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
KPFMNBKC_01533 3.9e-93 rimJ 2.3.1.128 J Alanine acetyltransferase
KPFMNBKC_01535 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
KPFMNBKC_01537 3.1e-122 V ABC transporter
KPFMNBKC_01538 1.6e-70 CP Membrane
KPFMNBKC_01539 4.8e-29
KPFMNBKC_01540 1.6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KPFMNBKC_01542 1.5e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
KPFMNBKC_01543 7.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
KPFMNBKC_01544 3.8e-27 yuiB S Putative membrane protein
KPFMNBKC_01545 3.5e-117 yuiC S protein conserved in bacteria
KPFMNBKC_01546 1.3e-76 yuiD S protein conserved in bacteria
KPFMNBKC_01547 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KPFMNBKC_01548 1.1e-208 yuiF S antiporter
KPFMNBKC_01549 1.1e-101 bioY S Biotin biosynthesis protein
KPFMNBKC_01550 7.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
KPFMNBKC_01551 4.7e-165 besA S Putative esterase
KPFMNBKC_01552 6.6e-134 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KPFMNBKC_01553 5.2e-223 entC 5.4.4.2 HQ Isochorismate synthase
KPFMNBKC_01554 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
KPFMNBKC_01555 8.6e-173 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
KPFMNBKC_01556 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_01557 1.3e-34 mbtH S MbtH-like protein
KPFMNBKC_01558 2.4e-132 yukJ S Uncharacterized conserved protein (DUF2278)
KPFMNBKC_01559 6.7e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KPFMNBKC_01560 1.2e-227 yukF QT Transcriptional regulator
KPFMNBKC_01561 3.3e-46 esxA S Belongs to the WXG100 family
KPFMNBKC_01562 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
KPFMNBKC_01563 2.4e-205 essB S WXG100 protein secretion system (Wss), protein YukC
KPFMNBKC_01564 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KPFMNBKC_01565 0.0 esaA S type VII secretion protein EsaA
KPFMNBKC_01566 6.5e-76 yueC S Family of unknown function (DUF5383)
KPFMNBKC_01567 4.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KPFMNBKC_01568 1.8e-95 yueE S phosphohydrolase
KPFMNBKC_01569 2.1e-22 S Protein of unknown function (DUF2642)
KPFMNBKC_01570 8.9e-185 yueF S transporter activity
KPFMNBKC_01571 3.2e-33 yueG S Spore germination protein gerPA/gerPF
KPFMNBKC_01572 2.8e-38 yueH S YueH-like protein
KPFMNBKC_01573 7.2e-68 yueI S Protein of unknown function (DUF1694)
KPFMNBKC_01574 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
KPFMNBKC_01575 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KPFMNBKC_01576 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
KPFMNBKC_01577 2.2e-49 yuzC
KPFMNBKC_01579 1.5e-147 comQ H Polyprenyl synthetase
KPFMNBKC_01581 0.0 comP 2.7.13.3 T Histidine kinase
KPFMNBKC_01582 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KPFMNBKC_01583 3.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
KPFMNBKC_01584 1.1e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
KPFMNBKC_01585 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KPFMNBKC_01586 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KPFMNBKC_01587 9.9e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KPFMNBKC_01588 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KPFMNBKC_01589 9.2e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KPFMNBKC_01590 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KPFMNBKC_01591 1.8e-12
KPFMNBKC_01592 2.7e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
KPFMNBKC_01593 5.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
KPFMNBKC_01594 2.8e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KPFMNBKC_01595 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KPFMNBKC_01596 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
KPFMNBKC_01597 1.3e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KPFMNBKC_01598 9.3e-74 yufK S Family of unknown function (DUF5366)
KPFMNBKC_01599 8.5e-72 yuxK S protein conserved in bacteria
KPFMNBKC_01600 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
KPFMNBKC_01601 7.7e-185 yuxJ EGP Major facilitator Superfamily
KPFMNBKC_01602 4.5e-118 kapD L the KinA pathway to sporulation
KPFMNBKC_01603 3.1e-68 kapB G Kinase associated protein B
KPFMNBKC_01604 5.8e-228 T PhoQ Sensor
KPFMNBKC_01605 2.7e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KPFMNBKC_01606 1.7e-38 yugE S Domain of unknown function (DUF1871)
KPFMNBKC_01607 1.6e-154 yugF I Hydrolase
KPFMNBKC_01608 2e-83 alaR K Transcriptional regulator
KPFMNBKC_01609 5.5e-209 yugH 2.6.1.1 E Aminotransferase
KPFMNBKC_01610 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KPFMNBKC_01611 1.8e-34 yuzA S Domain of unknown function (DUF378)
KPFMNBKC_01612 3.2e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KPFMNBKC_01613 2.8e-229 yugK C Dehydrogenase
KPFMNBKC_01614 4.2e-118 ycaC Q Isochorismatase family
KPFMNBKC_01615 4.7e-97 S NADPH-dependent FMN reductase
KPFMNBKC_01616 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
KPFMNBKC_01618 2.2e-72 yugN S YugN-like family
KPFMNBKC_01619 1.8e-181 yugO P COG1226 Kef-type K transport systems
KPFMNBKC_01620 1.1e-26 mstX S Membrane-integrating protein Mistic
KPFMNBKC_01621 4.5e-18
KPFMNBKC_01622 8.3e-117 yugP S Zn-dependent protease
KPFMNBKC_01623 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
KPFMNBKC_01624 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KPFMNBKC_01625 9.7e-76 yugU S Uncharacterised protein family UPF0047
KPFMNBKC_01626 2.5e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KPFMNBKC_01627 4.8e-41
KPFMNBKC_01628 1.3e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
KPFMNBKC_01629 1.7e-218 mcpA NT chemotaxis protein
KPFMNBKC_01630 1.2e-235 mcpA NT chemotaxis protein
KPFMNBKC_01631 9.3e-225 mcpA NT chemotaxis protein
KPFMNBKC_01632 2.3e-231 mcpA NT chemotaxis protein
KPFMNBKC_01633 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KPFMNBKC_01634 1.4e-184 ygjR S Oxidoreductase
KPFMNBKC_01635 7.6e-195 yubA S transporter activity
KPFMNBKC_01636 4e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KPFMNBKC_01638 4.6e-33 L Belongs to the 'phage' integrase family
KPFMNBKC_01639 1.4e-36 V Restriction endonuclease
KPFMNBKC_01642 6e-11 K Helix-turn-helix domain
KPFMNBKC_01643 5e-18
KPFMNBKC_01645 6.5e-183 S Aspartate phosphatase response regulator
KPFMNBKC_01646 5.7e-15
KPFMNBKC_01648 8.8e-10 yjcN
KPFMNBKC_01649 3.6e-122 G Cupin
KPFMNBKC_01650 4.5e-219 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KPFMNBKC_01651 4.3e-147 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KPFMNBKC_01652 9.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
KPFMNBKC_01653 2.1e-94 yuaB
KPFMNBKC_01654 6e-97 yuaC K Belongs to the GbsR family
KPFMNBKC_01655 9.4e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KPFMNBKC_01656 2.1e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
KPFMNBKC_01657 2.5e-109 yuaD S MOSC domain
KPFMNBKC_01658 4.3e-83 yuaE S DinB superfamily
KPFMNBKC_01659 1.5e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KPFMNBKC_01660 2.1e-176 yuaG 3.4.21.72 S protein conserved in bacteria
KPFMNBKC_01661 1.3e-97 thiT S Thiamine transporter protein (Thia_YuaJ)
KPFMNBKC_01662 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
KPFMNBKC_01663 1.3e-88 artQ E COG0765 ABC-type amino acid transport system, permease component
KPFMNBKC_01664 1.7e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KPFMNBKC_01665 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
KPFMNBKC_01666 4.8e-96 yqjB S protein conserved in bacteria
KPFMNBKC_01668 1.9e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
KPFMNBKC_01669 4.5e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KPFMNBKC_01670 1.4e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KPFMNBKC_01671 7.8e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KPFMNBKC_01672 3.1e-25 yqzJ
KPFMNBKC_01673 9.5e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPFMNBKC_01674 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KPFMNBKC_01675 2.5e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KPFMNBKC_01676 6.5e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KPFMNBKC_01677 1.3e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KPFMNBKC_01678 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KPFMNBKC_01679 4.1e-30 S GlpM protein
KPFMNBKC_01680 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
KPFMNBKC_01681 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KPFMNBKC_01684 2e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KPFMNBKC_01685 5.5e-130 IQ reductase
KPFMNBKC_01686 5.3e-164 ygxA S Nucleotidyltransferase-like
KPFMNBKC_01687 1.5e-56 ygzB S UPF0295 protein
KPFMNBKC_01688 1.8e-80 perR P Belongs to the Fur family
KPFMNBKC_01689 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
KPFMNBKC_01690 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KPFMNBKC_01691 1.6e-178 ygaE S Membrane
KPFMNBKC_01692 2.6e-300 ygaD V ABC transporter
KPFMNBKC_01693 2.2e-104 ygaC J Belongs to the UPF0374 family
KPFMNBKC_01694 1.5e-37 ygaB S YgaB-like protein
KPFMNBKC_01696 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KPFMNBKC_01697 8.2e-37 yfhS
KPFMNBKC_01698 1.4e-209 mutY L A G-specific
KPFMNBKC_01699 1e-184 yfhP S membrane-bound metal-dependent
KPFMNBKC_01700 0.0 yfhO S Bacterial membrane protein YfhO
KPFMNBKC_01701 3e-184 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KPFMNBKC_01702 4.1e-169 yfhM S Alpha/beta hydrolase family
KPFMNBKC_01703 5.7e-34 yfhL S SdpI/YhfL protein family
KPFMNBKC_01704 1.6e-94 batE T Bacterial SH3 domain homologues
KPFMNBKC_01705 2.2e-44 yfhJ S WVELL protein
KPFMNBKC_01706 1.7e-165 mpr 3.4.21.19 M Belongs to the peptidase S1B family
KPFMNBKC_01708 1.5e-206 yfhI EGP Major facilitator Superfamily
KPFMNBKC_01709 8.8e-53 yfhH S Protein of unknown function (DUF1811)
KPFMNBKC_01710 1.8e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
KPFMNBKC_01711 3e-134 yfhF S nucleoside-diphosphate sugar epimerase
KPFMNBKC_01712 6.2e-12 yfhF S nucleoside-diphosphate sugar epimerase
KPFMNBKC_01714 2.1e-25 yfhD S YfhD-like protein
KPFMNBKC_01715 2.2e-105 yfhC C nitroreductase
KPFMNBKC_01716 9.7e-166 yfhB 5.3.3.17 S PhzF family
KPFMNBKC_01717 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KPFMNBKC_01718 8.1e-82 yfiV K transcriptional
KPFMNBKC_01721 7e-251 iolT EGP Major facilitator Superfamily
KPFMNBKC_01722 8.1e-185 yhfP 1.1.1.1 C Quinone oxidoreductase
KPFMNBKC_01723 1e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
KPFMNBKC_01724 3.2e-166 ydhU P Catalase
KPFMNBKC_01725 3.5e-296 yveA E amino acid
KPFMNBKC_01726 5.3e-104 yvdT K Transcriptional regulator
KPFMNBKC_01727 2.3e-51 ykkC P Small Multidrug Resistance protein
KPFMNBKC_01728 2.6e-49 sugE P Small Multidrug Resistance protein
KPFMNBKC_01729 6.9e-215 yeaN P COG2807 Cyanate permease
KPFMNBKC_01730 2.6e-118 K FCD
KPFMNBKC_01731 1.9e-132 ydhQ K UTRA
KPFMNBKC_01732 1.5e-195 pbuE EGP Major facilitator Superfamily
KPFMNBKC_01733 2.5e-98 ydhK M Protein of unknown function (DUF1541)
KPFMNBKC_01735 4.8e-265 pbpE V Beta-lactamase
KPFMNBKC_01738 1.4e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KPFMNBKC_01739 8.1e-120 ydhC K FCD
KPFMNBKC_01740 4.7e-22 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KPFMNBKC_01743 1e-70 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KPFMNBKC_01744 2e-146 ycgJ_1 Q ubiE/COQ5 methyltransferase family
KPFMNBKC_01745 1.9e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
KPFMNBKC_01746 2.8e-149 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KPFMNBKC_01747 2.9e-148 bltR K helix_turn_helix, mercury resistance
KPFMNBKC_01748 5.9e-82 bltD 2.3.1.57 K FR47-like protein
KPFMNBKC_01749 2.2e-123 ydhB S membrane transporter protein
KPFMNBKC_01750 3.9e-156 K Helix-turn-helix XRE-family like proteins
KPFMNBKC_01751 5.8e-225 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KPFMNBKC_01752 0.0 pksJ Q Polyketide synthase of type I
KPFMNBKC_01753 0.0 1.1.1.320 Q Polyketide synthase of type I
KPFMNBKC_01754 0.0 Q Polyketide synthase of type I
KPFMNBKC_01755 1.2e-112 K Protein of unknown function (DUF1232)
KPFMNBKC_01756 1.5e-101 ytaF P Probably functions as a manganese efflux pump
KPFMNBKC_01757 2.5e-17
KPFMNBKC_01758 1.4e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
KPFMNBKC_01759 2.5e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KPFMNBKC_01760 1.8e-212 mmgA 2.3.1.9 I Belongs to the thiolase family
KPFMNBKC_01761 1.4e-153 hbdA 1.1.1.157 I Dehydrogenase
KPFMNBKC_01762 8.5e-207 mmgC I acyl-CoA dehydrogenase
KPFMNBKC_01763 2.4e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KPFMNBKC_01764 4.4e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KPFMNBKC_01765 4.8e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KPFMNBKC_01766 3.2e-34 yqzF S Protein of unknown function (DUF2627)
KPFMNBKC_01767 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
KPFMNBKC_01768 9.5e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
KPFMNBKC_01769 2e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KPFMNBKC_01770 7.5e-208 buk 2.7.2.7 C Belongs to the acetokinase family
KPFMNBKC_01771 1e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KPFMNBKC_01772 8.6e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KPFMNBKC_01773 2.3e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KPFMNBKC_01774 3.6e-190 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KPFMNBKC_01775 1.3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KPFMNBKC_01776 1.7e-75 yqiW S Belongs to the UPF0403 family
KPFMNBKC_01777 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
KPFMNBKC_01778 3.6e-32 yaaL S Protein of unknown function (DUF2508)
KPFMNBKC_01779 8.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KPFMNBKC_01780 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KPFMNBKC_01781 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPFMNBKC_01782 7.8e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KPFMNBKC_01783 9.8e-100 yaaI Q COG1335 Amidases related to nicotinamidase
KPFMNBKC_01784 2e-212 yaaH M Glycoside Hydrolase Family
KPFMNBKC_01785 1.2e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KPFMNBKC_01786 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KPFMNBKC_01787 1.3e-09
KPFMNBKC_01788 1.8e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KPFMNBKC_01789 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KPFMNBKC_01790 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KPFMNBKC_01791 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KPFMNBKC_01792 1.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KPFMNBKC_01793 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KPFMNBKC_01794 1.5e-183 yaaC S YaaC-like Protein
KPFMNBKC_01795 1.1e-197 L COG3666 Transposase and inactivated derivatives
KPFMNBKC_01796 3.4e-39 S COG NOG14552 non supervised orthologous group
KPFMNBKC_01797 7.6e-109 ymaB S MutT family
KPFMNBKC_01798 1.3e-187 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPFMNBKC_01799 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPFMNBKC_01800 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KPFMNBKC_01801 1.8e-20 ymzA
KPFMNBKC_01802 2.2e-44
KPFMNBKC_01803 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KPFMNBKC_01804 3.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KPFMNBKC_01805 1.4e-47 ymaF S YmaF family
KPFMNBKC_01807 3.1e-48 ebrA P Small Multidrug Resistance protein
KPFMNBKC_01808 5.2e-54 ebrB P Small Multidrug Resistance protein
KPFMNBKC_01809 3.9e-78 ymaD O redox protein, regulator of disulfide bond formation
KPFMNBKC_01810 6e-126 ymaC S Replication protein
KPFMNBKC_01812 1.1e-253 aprX O Belongs to the peptidase S8 family
KPFMNBKC_01813 1.4e-62 ymzB
KPFMNBKC_01814 9.4e-119 yoaK S Membrane
KPFMNBKC_01815 4.1e-77 nucB M Deoxyribonuclease NucA/NucB
KPFMNBKC_01816 8.1e-232 cypA C Cytochrome P450
KPFMNBKC_01817 0.0 pks13 HQ Beta-ketoacyl synthase
KPFMNBKC_01818 0.0 dhbF IQ polyketide synthase
KPFMNBKC_01819 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
KPFMNBKC_01820 0.0 Q Polyketide synthase of type I
KPFMNBKC_01821 0.0 rhiB IQ polyketide synthase
KPFMNBKC_01822 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KPFMNBKC_01823 4.1e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
KPFMNBKC_01824 6.7e-245 pksG 2.3.3.10 I synthase
KPFMNBKC_01825 6.5e-35 acpK IQ Phosphopantetheine attachment site
KPFMNBKC_01826 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KPFMNBKC_01827 3.9e-184 pksD Q Acyl transferase domain
KPFMNBKC_01828 7e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KPFMNBKC_01829 1.3e-128 pksB 3.1.2.6 S Polyketide biosynthesis
KPFMNBKC_01831 9.1e-31
KPFMNBKC_01832 3.4e-41 L Belongs to the 'phage' integrase family
KPFMNBKC_01833 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KPFMNBKC_01834 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KPFMNBKC_01835 1.7e-88 cotE S Spore coat protein
KPFMNBKC_01836 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KPFMNBKC_01837 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KPFMNBKC_01838 3.9e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KPFMNBKC_01839 1.9e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KPFMNBKC_01840 1.2e-36 spoVS S Stage V sporulation protein S
KPFMNBKC_01841 4.9e-153 ymdB S protein conserved in bacteria
KPFMNBKC_01842 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
KPFMNBKC_01843 8.9e-183 pbpX V Beta-lactamase
KPFMNBKC_01844 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KPFMNBKC_01845 1.7e-232 cinA 3.5.1.42 S Belongs to the CinA family
KPFMNBKC_01846 1.1e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KPFMNBKC_01847 4.2e-124 ymfM S protein conserved in bacteria
KPFMNBKC_01848 3.5e-143 ymfK S Protein of unknown function (DUF3388)
KPFMNBKC_01849 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
KPFMNBKC_01850 1.3e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KPFMNBKC_01851 7.1e-242 ymfH S zinc protease
KPFMNBKC_01852 2.6e-236 ymfF S Peptidase M16
KPFMNBKC_01853 0.0 ydgH S drug exporters of the RND superfamily
KPFMNBKC_01854 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
KPFMNBKC_01855 1.1e-229 ymfD EGP Major facilitator Superfamily
KPFMNBKC_01856 1.8e-133 ymfC K Transcriptional regulator
KPFMNBKC_01857 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KPFMNBKC_01858 6.3e-31 S YlzJ-like protein
KPFMNBKC_01859 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KPFMNBKC_01860 5.7e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPFMNBKC_01861 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KPFMNBKC_01862 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KPFMNBKC_01863 1.9e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KPFMNBKC_01864 9.8e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KPFMNBKC_01865 6.1e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KPFMNBKC_01866 2.6e-42 ymxH S YlmC YmxH family
KPFMNBKC_01867 3e-234 pepR S Belongs to the peptidase M16 family
KPFMNBKC_01868 4e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KPFMNBKC_01869 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KPFMNBKC_01870 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KPFMNBKC_01871 3.5e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KPFMNBKC_01872 5.2e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KPFMNBKC_01873 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KPFMNBKC_01874 3.9e-44 ylxP S protein conserved in bacteria
KPFMNBKC_01875 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KPFMNBKC_01876 4e-47 ylxQ J ribosomal protein
KPFMNBKC_01877 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
KPFMNBKC_01878 5.4e-206 nusA K Participates in both transcription termination and antitermination
KPFMNBKC_01879 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
KPFMNBKC_01880 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPFMNBKC_01881 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KPFMNBKC_01882 1.5e-233 rasP M zinc metalloprotease
KPFMNBKC_01883 7.3e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KPFMNBKC_01884 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
KPFMNBKC_01885 2.2e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KPFMNBKC_01886 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KPFMNBKC_01887 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KPFMNBKC_01888 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KPFMNBKC_01889 1.4e-130 rpsB J Belongs to the universal ribosomal protein uS2 family
KPFMNBKC_01890 2.5e-51 ylxL
KPFMNBKC_01891 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KPFMNBKC_01892 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KPFMNBKC_01893 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KPFMNBKC_01894 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
KPFMNBKC_01895 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KPFMNBKC_01896 8.6e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KPFMNBKC_01897 2.7e-155 flhG D Belongs to the ParA family
KPFMNBKC_01898 2.7e-194 flhF N Flagellar biosynthesis regulator FlhF
KPFMNBKC_01899 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KPFMNBKC_01900 3.1e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KPFMNBKC_01901 2e-130 fliR N Flagellar biosynthetic protein FliR
KPFMNBKC_01902 2e-37 fliQ N Role in flagellar biosynthesis
KPFMNBKC_01903 4.3e-110 fliP N Plays a role in the flagellum-specific transport system
KPFMNBKC_01904 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
KPFMNBKC_01905 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
KPFMNBKC_01906 5.4e-185 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KPFMNBKC_01907 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KPFMNBKC_01908 7.8e-57 fliL N Controls the rotational direction of flagella during chemotaxis
KPFMNBKC_01909 4e-139 flgG N Flagellar basal body rod
KPFMNBKC_01910 4.8e-73 flgD N Flagellar basal body rod modification protein
KPFMNBKC_01911 2.7e-204 fliK N Flagellar hook-length control protein
KPFMNBKC_01912 1.3e-47 ylxF S MgtE intracellular N domain
KPFMNBKC_01913 1.7e-70 fliJ N Flagellar biosynthesis chaperone
KPFMNBKC_01914 5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KPFMNBKC_01915 3.7e-89 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KPFMNBKC_01916 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KPFMNBKC_01917 1.5e-257 fliF N The M ring may be actively involved in energy transduction
KPFMNBKC_01918 2.5e-31 fliE N Flagellar hook-basal body
KPFMNBKC_01919 1.2e-74 flgC N Belongs to the flagella basal body rod proteins family
KPFMNBKC_01920 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KPFMNBKC_01921 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KPFMNBKC_01922 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KPFMNBKC_01923 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KPFMNBKC_01924 7.2e-172 xerC L tyrosine recombinase XerC
KPFMNBKC_01925 3.7e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KPFMNBKC_01926 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KPFMNBKC_01927 6.8e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KPFMNBKC_01928 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KPFMNBKC_01929 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KPFMNBKC_01930 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KPFMNBKC_01931 2.3e-304 ylqG
KPFMNBKC_01932 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPFMNBKC_01933 9.3e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KPFMNBKC_01934 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KPFMNBKC_01935 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KPFMNBKC_01936 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KPFMNBKC_01937 1.3e-61 ylqD S YlqD protein
KPFMNBKC_01938 1.7e-35 ylqC S Belongs to the UPF0109 family
KPFMNBKC_01939 4.2e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KPFMNBKC_01940 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KPFMNBKC_01941 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KPFMNBKC_01942 8.5e-142 S Phosphotransferase enzyme family
KPFMNBKC_01943 4.1e-173 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KPFMNBKC_01944 0.0 smc D Required for chromosome condensation and partitioning
KPFMNBKC_01945 1.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KPFMNBKC_01946 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPFMNBKC_01947 4.6e-129 IQ reductase
KPFMNBKC_01948 2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KPFMNBKC_01949 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KPFMNBKC_01950 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KPFMNBKC_01951 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KPFMNBKC_01952 7.1e-156 sdaAA 4.3.1.17 E L-serine dehydratase
KPFMNBKC_01953 4.8e-117 sdaAB 4.3.1.17 E L-serine dehydratase
KPFMNBKC_01954 3.8e-304 yloV S kinase related to dihydroxyacetone kinase
KPFMNBKC_01955 5.5e-59 asp S protein conserved in bacteria
KPFMNBKC_01956 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KPFMNBKC_01957 1.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
KPFMNBKC_01958 9.4e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KPFMNBKC_01959 8.2e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KPFMNBKC_01960 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KPFMNBKC_01961 1.7e-139 stp 3.1.3.16 T phosphatase
KPFMNBKC_01962 3.4e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KPFMNBKC_01963 6.6e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KPFMNBKC_01964 6.6e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KPFMNBKC_01965 3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KPFMNBKC_01966 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KPFMNBKC_01967 9.7e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KPFMNBKC_01968 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KPFMNBKC_01969 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KPFMNBKC_01970 1.5e-40 ylzA S Belongs to the UPF0296 family
KPFMNBKC_01971 6.5e-154 yloC S stress-induced protein
KPFMNBKC_01972 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KPFMNBKC_01973 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KPFMNBKC_01974 4.5e-80 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KPFMNBKC_01975 7.6e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KPFMNBKC_01976 5.3e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KPFMNBKC_01977 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
KPFMNBKC_01978 1.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KPFMNBKC_01979 9.2e-179 cysP P phosphate transporter
KPFMNBKC_01980 8.5e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KPFMNBKC_01982 3.8e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KPFMNBKC_01983 1.1e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KPFMNBKC_01984 6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KPFMNBKC_01985 5.9e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KPFMNBKC_01986 0.0 carB 6.3.5.5 F Belongs to the CarB family
KPFMNBKC_01987 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KPFMNBKC_01988 2.3e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KPFMNBKC_01989 5.3e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KPFMNBKC_01990 8e-233 pyrP F Xanthine uracil
KPFMNBKC_01991 1.8e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KPFMNBKC_01992 1.8e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KPFMNBKC_01993 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KPFMNBKC_01994 3.8e-63 dksA T COG1734 DnaK suppressor protein
KPFMNBKC_01995 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KPFMNBKC_01996 8.9e-68 divIVA D Cell division initiation protein
KPFMNBKC_01997 3.6e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KPFMNBKC_01998 5.2e-41 yggT S membrane
KPFMNBKC_01999 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KPFMNBKC_02000 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KPFMNBKC_02001 4.4e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KPFMNBKC_02002 2.2e-38 ylmC S sporulation protein
KPFMNBKC_02003 4.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
KPFMNBKC_02004 2.9e-145 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KPFMNBKC_02005 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KPFMNBKC_02006 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KPFMNBKC_02007 5.8e-161 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KPFMNBKC_02008 0.0 bpr O COG1404 Subtilisin-like serine proteases
KPFMNBKC_02009 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KPFMNBKC_02010 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KPFMNBKC_02011 8.7e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KPFMNBKC_02012 3.7e-168 murB 1.3.1.98 M cell wall formation
KPFMNBKC_02013 8.7e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KPFMNBKC_02014 2.2e-185 spoVE D Belongs to the SEDS family
KPFMNBKC_02015 1.7e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KPFMNBKC_02016 2.2e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KPFMNBKC_02017 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KPFMNBKC_02018 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KPFMNBKC_02019 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KPFMNBKC_02020 2.9e-52 ftsL D Essential cell division protein
KPFMNBKC_02021 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KPFMNBKC_02022 8.9e-78 mraZ K Belongs to the MraZ family
KPFMNBKC_02023 7e-311 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KPFMNBKC_02024 1.1e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KPFMNBKC_02025 8.1e-90 ylbP K n-acetyltransferase
KPFMNBKC_02026 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KPFMNBKC_02027 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KPFMNBKC_02028 3.6e-88 yceD S metal-binding, possibly nucleic acid-binding protein
KPFMNBKC_02029 1e-229 ylbM S Belongs to the UPF0348 family
KPFMNBKC_02030 6.7e-187 ylbL T Belongs to the peptidase S16 family
KPFMNBKC_02031 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
KPFMNBKC_02032 1.1e-215 ylbJ S Sporulation integral membrane protein YlbJ
KPFMNBKC_02033 2.8e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KPFMNBKC_02034 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
KPFMNBKC_02036 7.2e-43 ylbG S UPF0298 protein
KPFMNBKC_02037 1.2e-71 ylbF S Belongs to the UPF0342 family
KPFMNBKC_02038 8.8e-37 ylbE S YlbE-like protein
KPFMNBKC_02039 1.3e-56 ylbD S Putative coat protein
KPFMNBKC_02040 1.5e-197 ylbC S protein with SCP PR1 domains
KPFMNBKC_02041 3.1e-72 ylbB T COG0517 FOG CBS domain
KPFMNBKC_02042 8.5e-60 ylbA S YugN-like family
KPFMNBKC_02043 4.8e-165 ctaG S cytochrome c oxidase
KPFMNBKC_02044 4.6e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KPFMNBKC_02045 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KPFMNBKC_02046 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KPFMNBKC_02047 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KPFMNBKC_02048 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KPFMNBKC_02049 2e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KPFMNBKC_02050 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KPFMNBKC_02051 4.5e-214 ftsW D Belongs to the SEDS family
KPFMNBKC_02052 8.7e-44 ylaN S Belongs to the UPF0358 family
KPFMNBKC_02053 5.4e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
KPFMNBKC_02054 2.2e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KPFMNBKC_02055 1.2e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KPFMNBKC_02056 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KPFMNBKC_02057 1e-33 ylaI S protein conserved in bacteria
KPFMNBKC_02058 1.7e-48 ylaH S YlaH-like protein
KPFMNBKC_02059 0.0 typA T GTP-binding protein TypA
KPFMNBKC_02060 6.7e-24 S Family of unknown function (DUF5325)
KPFMNBKC_02061 6.3e-39 ylaE
KPFMNBKC_02062 3.7e-13 sigC S Putative zinc-finger
KPFMNBKC_02063 3.8e-93 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
KPFMNBKC_02064 1.7e-44 ylaB
KPFMNBKC_02065 3.1e-193 ylaA
KPFMNBKC_02066 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
KPFMNBKC_02067 5.8e-82 ykzC S Acetyltransferase (GNAT) family
KPFMNBKC_02068 2.3e-150 suhB 3.1.3.25 G Inositol monophosphatase
KPFMNBKC_02069 9.7e-25 ykzI
KPFMNBKC_02070 4.9e-119 yktB S Belongs to the UPF0637 family
KPFMNBKC_02071 1.6e-42 yktA S Belongs to the UPF0223 family
KPFMNBKC_02072 3.1e-278 speA 4.1.1.19 E Arginine
KPFMNBKC_02073 7.7e-138 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
KPFMNBKC_02074 2.1e-45 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
KPFMNBKC_02075 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KPFMNBKC_02076 1.3e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KPFMNBKC_02077 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KPFMNBKC_02078 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KPFMNBKC_02079 4.3e-208 V Beta-lactamase
KPFMNBKC_02080 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
KPFMNBKC_02081 0.0 Q Polyketide synthase of type I
KPFMNBKC_02082 0.0 Q Polyketide synthase of type I
KPFMNBKC_02083 0.0 Q Polyketide synthase of type I
KPFMNBKC_02084 0.0 Q Polyketide synthase of type I
KPFMNBKC_02085 0.0 Q polyketide synthase
KPFMNBKC_02086 0.0 Q Polyketide synthase of type I
KPFMNBKC_02087 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KPFMNBKC_02088 5e-103 recN L Putative cell-wall binding lipoprotein
KPFMNBKC_02090 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KPFMNBKC_02091 8e-148 ykrA S hydrolases of the HAD superfamily
KPFMNBKC_02092 8.2e-31 ykzG S Belongs to the UPF0356 family
KPFMNBKC_02093 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPFMNBKC_02094 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KPFMNBKC_02095 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
KPFMNBKC_02096 2.9e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
KPFMNBKC_02097 6.3e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KPFMNBKC_02098 2.1e-45 abrB K of stationary sporulation gene expression
KPFMNBKC_02099 1e-182 mreB D Rod-share determining protein MreBH
KPFMNBKC_02100 5.5e-12 S Uncharacterized protein YkpC
KPFMNBKC_02101 5e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KPFMNBKC_02102 5.3e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KPFMNBKC_02103 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KPFMNBKC_02104 9.8e-37 ykoA
KPFMNBKC_02105 1.9e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KPFMNBKC_02106 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KPFMNBKC_02107 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KPFMNBKC_02108 1e-131 fruR K Transcriptional regulator
KPFMNBKC_02109 3e-210 yknZ V ABC transporter (permease)
KPFMNBKC_02110 3e-122 macB V ABC transporter, ATP-binding protein
KPFMNBKC_02111 1.4e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KPFMNBKC_02112 1.2e-105 yknW S Yip1 domain
KPFMNBKC_02113 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KPFMNBKC_02114 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KPFMNBKC_02115 4.5e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KPFMNBKC_02116 1.2e-244 moeA 2.10.1.1 H molybdopterin
KPFMNBKC_02117 2.5e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KPFMNBKC_02118 1.4e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KPFMNBKC_02119 2.5e-162 yknT
KPFMNBKC_02120 4.5e-98 rok K Repressor of ComK
KPFMNBKC_02121 1.4e-69 ykuV CO thiol-disulfide
KPFMNBKC_02122 7e-139 ykuT M Mechanosensitive ion channel
KPFMNBKC_02123 4.8e-38 ykuS S Belongs to the UPF0180 family
KPFMNBKC_02124 7.6e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KPFMNBKC_02125 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KPFMNBKC_02126 1.3e-78 fld C Flavodoxin
KPFMNBKC_02127 1.1e-169 ykuO
KPFMNBKC_02128 6.1e-90 fld C Flavodoxin
KPFMNBKC_02129 4.6e-168 ccpC K Transcriptional regulator
KPFMNBKC_02130 1e-75 ykuL S CBS domain
KPFMNBKC_02131 2.1e-25 ykzF S Antirepressor AbbA
KPFMNBKC_02132 4.9e-93 ykuK S Ribonuclease H-like
KPFMNBKC_02133 3.9e-37 ykuJ S protein conserved in bacteria
KPFMNBKC_02134 1.5e-233 ykuI T Diguanylate phosphodiesterase
KPFMNBKC_02136 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KPFMNBKC_02137 8.9e-156 ykuE S Metallophosphoesterase
KPFMNBKC_02138 9.2e-89 ykuD S protein conserved in bacteria
KPFMNBKC_02139 3e-240 ykuC EGP Major facilitator Superfamily
KPFMNBKC_02140 1.4e-83 ykyB S YkyB-like protein
KPFMNBKC_02141 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
KPFMNBKC_02142 2.3e-09
KPFMNBKC_02143 3.9e-215 patA 2.6.1.1 E Aminotransferase
KPFMNBKC_02144 4.4e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
KPFMNBKC_02145 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
KPFMNBKC_02146 4.9e-113 ykwD J protein with SCP PR1 domains
KPFMNBKC_02147 3.9e-50
KPFMNBKC_02148 2.3e-156 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KPFMNBKC_02149 1.2e-264 mcpC NT chemotaxis protein
KPFMNBKC_02150 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
KPFMNBKC_02151 1.4e-37 splA S Transcriptional regulator
KPFMNBKC_02152 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KPFMNBKC_02153 2.1e-39 ptsH G phosphocarrier protein HPr
KPFMNBKC_02154 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KPFMNBKC_02155 4.3e-155 glcT K antiterminator
KPFMNBKC_02156 1e-176 ykvZ 5.1.1.1 K Transcriptional regulator
KPFMNBKC_02158 2.4e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KPFMNBKC_02159 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KPFMNBKC_02160 5.9e-88 stoA CO thiol-disulfide
KPFMNBKC_02161 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KPFMNBKC_02162 1.8e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
KPFMNBKC_02163 7.9e-28
KPFMNBKC_02164 7.8e-25 ykvS S protein conserved in bacteria
KPFMNBKC_02165 1.6e-42 ykvR S Protein of unknown function (DUF3219)
KPFMNBKC_02166 1e-131 IQ Enoyl-(Acyl carrier protein) reductase
KPFMNBKC_02167 3.4e-58 ykvN K Transcriptional regulator
KPFMNBKC_02169 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KPFMNBKC_02170 6.4e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KPFMNBKC_02171 1.8e-80 queD 4.1.2.50, 4.2.3.12 H synthase
KPFMNBKC_02172 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KPFMNBKC_02173 2.5e-187
KPFMNBKC_02174 1.3e-182 ykvI S membrane
KPFMNBKC_02175 0.0 clpE O Belongs to the ClpA ClpB family
KPFMNBKC_02176 1.1e-136 motA N flagellar motor
KPFMNBKC_02177 2.7e-127 motB N Flagellar motor protein
KPFMNBKC_02178 5.5e-77 ykvE K transcriptional
KPFMNBKC_02179 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
KPFMNBKC_02180 3.4e-10 S Spo0E like sporulation regulatory protein
KPFMNBKC_02181 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KPFMNBKC_02182 6.5e-116 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KPFMNBKC_02183 1.1e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KPFMNBKC_02184 1.3e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KPFMNBKC_02185 1.2e-227 mtnE 2.6.1.83 E Aminotransferase
KPFMNBKC_02186 8.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KPFMNBKC_02187 2.2e-226 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KPFMNBKC_02188 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KPFMNBKC_02190 1.1e-84 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KPFMNBKC_02191 0.0 kinE 2.7.13.3 T Histidine kinase
KPFMNBKC_02192 2.5e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KPFMNBKC_02193 7.9e-24 ykzE
KPFMNBKC_02194 1.6e-112 ydfR S Protein of unknown function (DUF421)
KPFMNBKC_02195 4.3e-242 ktrB P COG0168 Trk-type K transport systems, membrane components
KPFMNBKC_02196 4.1e-156 htpX O Belongs to the peptidase M48B family
KPFMNBKC_02197 2.3e-125 ykrK S Domain of unknown function (DUF1836)
KPFMNBKC_02198 2.5e-26 sspD S small acid-soluble spore protein
KPFMNBKC_02199 3.1e-119 rsgI S Anti-sigma factor N-terminus
KPFMNBKC_02200 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KPFMNBKC_02201 3e-134 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KPFMNBKC_02202 6.6e-99 ykoX S membrane-associated protein
KPFMNBKC_02203 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KPFMNBKC_02204 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
KPFMNBKC_02205 2.2e-99 ykoP G polysaccharide deacetylase
KPFMNBKC_02206 5e-81 ykoM K transcriptional
KPFMNBKC_02207 3.1e-26 ykoL
KPFMNBKC_02208 1.9e-16
KPFMNBKC_02209 5.4e-53 tnrA K transcriptional
KPFMNBKC_02210 4.2e-237 mgtE P Acts as a magnesium transporter
KPFMNBKC_02212 1e-245 ydhD M Glycosyl hydrolase
KPFMNBKC_02213 2.2e-97 ykoE S ABC-type cobalt transport system, permease component
KPFMNBKC_02214 1.2e-307 P ABC transporter, ATP-binding protein
KPFMNBKC_02215 1.8e-131 ykoC P Cobalt transport protein
KPFMNBKC_02216 1.2e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KPFMNBKC_02217 2.5e-175 isp O Belongs to the peptidase S8 family
KPFMNBKC_02218 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KPFMNBKC_02219 3.3e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KPFMNBKC_02220 2.7e-216 hcaT 1.5.1.2 EGP Major facilitator Superfamily
KPFMNBKC_02221 7.5e-125 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
KPFMNBKC_02222 2.2e-215 M Glycosyl transferase family 2
KPFMNBKC_02224 1.3e-57 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KPFMNBKC_02225 7.9e-70 ohrB O Organic hydroperoxide resistance protein
KPFMNBKC_02226 2.2e-85 ohrR K COG1846 Transcriptional regulators
KPFMNBKC_02227 9.6e-71 ohrA O Organic hydroperoxide resistance protein
KPFMNBKC_02228 3.6e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KPFMNBKC_02229 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KPFMNBKC_02230 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KPFMNBKC_02231 3.4e-49 ykkD P Multidrug resistance protein
KPFMNBKC_02232 9.4e-53 ykkC P Multidrug resistance protein
KPFMNBKC_02233 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KPFMNBKC_02234 1.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KPFMNBKC_02235 2.5e-158 ykgA E Amidinotransferase
KPFMNBKC_02236 5.1e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
KPFMNBKC_02237 2.1e-182 ykfD E Belongs to the ABC transporter superfamily
KPFMNBKC_02238 1.6e-171 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KPFMNBKC_02239 3e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KPFMNBKC_02240 6.4e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KPFMNBKC_02241 0.0 dppE E ABC transporter substrate-binding protein
KPFMNBKC_02242 7.7e-191 dppD P Belongs to the ABC transporter superfamily
KPFMNBKC_02243 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPFMNBKC_02244 1.9e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPFMNBKC_02245 1.6e-154 dppA E D-aminopeptidase
KPFMNBKC_02247 1.8e-284 yubD P Major Facilitator Superfamily
KPFMNBKC_02248 3.3e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KPFMNBKC_02250 2.9e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KPFMNBKC_02251 3.8e-309 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KPFMNBKC_02252 4.8e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
KPFMNBKC_02253 3.2e-242 steT E amino acid
KPFMNBKC_02254 3.2e-107 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
KPFMNBKC_02255 5.8e-175 pit P phosphate transporter
KPFMNBKC_02256 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KPFMNBKC_02257 8.7e-23 spoIISB S Stage II sporulation protein SB
KPFMNBKC_02258 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KPFMNBKC_02259 1.3e-38 xhlB S SPP1 phage holin
KPFMNBKC_02260 8.7e-38 xhlA S Haemolysin XhlA
KPFMNBKC_02261 6.6e-139 xepA
KPFMNBKC_02262 6.5e-30 xkdX
KPFMNBKC_02264 3.8e-91
KPFMNBKC_02265 1.2e-26
KPFMNBKC_02266 5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KPFMNBKC_02267 5.1e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KPFMNBKC_02268 1.4e-56 xkdS S Protein of unknown function (DUF2634)
KPFMNBKC_02269 7.2e-32 xkdR S Protein of unknown function (DUF2577)
KPFMNBKC_02270 2.7e-161 xkdQ 3.2.1.96 G NLP P60 protein
KPFMNBKC_02271 6.6e-111 xkdP S Lysin motif
KPFMNBKC_02272 1.2e-183 xkdO L Transglycosylase SLT domain
KPFMNBKC_02273 3.4e-19
KPFMNBKC_02274 4.9e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
KPFMNBKC_02275 2e-74 xkdM S Phage tail tube protein
KPFMNBKC_02276 1e-225 xkdK S Phage tail sheath C-terminal domain
KPFMNBKC_02277 3.1e-14
KPFMNBKC_02278 8.3e-57 xkdJ
KPFMNBKC_02279 9.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
KPFMNBKC_02280 4.2e-43 yqbH S Domain of unknown function (DUF3599)
KPFMNBKC_02281 3.3e-46 yqbG S Protein of unknown function (DUF3199)
KPFMNBKC_02282 1e-157 xkdG S Phage capsid family
KPFMNBKC_02283 7.5e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
KPFMNBKC_02284 1.3e-241 yqbA S portal protein
KPFMNBKC_02285 7.9e-209 xtmB S phage terminase, large subunit
KPFMNBKC_02286 6.8e-110 xtmA L phage terminase small subunit
KPFMNBKC_02287 6.3e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KPFMNBKC_02288 2e-10 yqaO S Phage-like element PBSX protein XtrA
KPFMNBKC_02291 8.5e-153 xkdC L Bacterial dnaA protein
KPFMNBKC_02293 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
KPFMNBKC_02294 2.3e-110 xkdA E IrrE N-terminal-like domain
KPFMNBKC_02296 6.7e-110 yjqB S phage-related replication protein
KPFMNBKC_02297 4.7e-61 yjqA S Bacterial PH domain
KPFMNBKC_02298 8.5e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KPFMNBKC_02300 4.9e-215 S response regulator aspartate phosphatase
KPFMNBKC_02301 3.1e-78 yjoA S DinB family
KPFMNBKC_02302 3.9e-131 MA20_18170 S membrane transporter protein
KPFMNBKC_02303 1.1e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KPFMNBKC_02304 1.5e-277 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KPFMNBKC_02305 3.4e-183 exuR K transcriptional
KPFMNBKC_02306 1.9e-253 yjmB G symporter YjmB
KPFMNBKC_02307 1.5e-277 uxaC 5.3.1.12 G glucuronate isomerase
KPFMNBKC_02308 1.3e-218 yjlD 1.6.99.3 C NADH dehydrogenase
KPFMNBKC_02309 7e-66 yjlC S Protein of unknown function (DUF1641)
KPFMNBKC_02310 7.5e-91 yjlB S Cupin domain
KPFMNBKC_02311 1.6e-177 yjlA EG Putative multidrug resistance efflux transporter
KPFMNBKC_02312 6.4e-131 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
KPFMNBKC_02313 1.6e-122 ybbM S transport system, permease component
KPFMNBKC_02314 3.3e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KPFMNBKC_02315 4.4e-28
KPFMNBKC_02316 2.3e-223 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KPFMNBKC_02317 9.4e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
KPFMNBKC_02318 1.6e-91 yjgD S Protein of unknown function (DUF1641)
KPFMNBKC_02319 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KPFMNBKC_02320 1.7e-102 yjgB S Domain of unknown function (DUF4309)
KPFMNBKC_02321 6.7e-66 T PhoQ Sensor
KPFMNBKC_02322 7.5e-22 yjfB S Putative motility protein
KPFMNBKC_02324 8.1e-106 yhiD S MgtC SapB transporter
KPFMNBKC_02327 7.8e-123 5.4.2.6 S Haloacid dehalogenase-like hydrolase
KPFMNBKC_02328 2.2e-137 lacR K COG1349 Transcriptional regulators of sugar metabolism
KPFMNBKC_02329 6.2e-284 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
KPFMNBKC_02330 2e-49 lacF 2.7.1.207 G phosphotransferase system
KPFMNBKC_02331 1.2e-310 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPFMNBKC_02332 2.5e-214 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KPFMNBKC_02333 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KPFMNBKC_02334 4.8e-290 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KPFMNBKC_02335 2.3e-220 ganA 3.2.1.89 G arabinogalactan
KPFMNBKC_02336 1.4e-81 napB K helix_turn_helix multiple antibiotic resistance protein
KPFMNBKC_02337 5.9e-250 yfjF EGP Belongs to the major facilitator superfamily
KPFMNBKC_02338 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
KPFMNBKC_02339 1.6e-163 bla 3.5.2.6 V beta-lactamase
KPFMNBKC_02340 3.5e-59 E Glyoxalase-like domain
KPFMNBKC_02343 2.1e-204 M nucleic acid phosphodiester bond hydrolysis
KPFMNBKC_02344 6.4e-29
KPFMNBKC_02345 2.7e-38
KPFMNBKC_02346 3.4e-22
KPFMNBKC_02347 8.4e-54 L COG2963 Transposase and inactivated derivatives
KPFMNBKC_02349 1.6e-08
KPFMNBKC_02352 6e-21
KPFMNBKC_02353 1.2e-44 L COG2963 Transposase and inactivated derivatives
KPFMNBKC_02360 2e-08
KPFMNBKC_02363 1.6e-08
KPFMNBKC_02367 1.9e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KPFMNBKC_02368 1.3e-176 spoVK O stage V sporulation protein K
KPFMNBKC_02369 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KPFMNBKC_02370 6.3e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KPFMNBKC_02371 1.6e-67 glnR K transcriptional
KPFMNBKC_02372 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
KPFMNBKC_02374 6.5e-13
KPFMNBKC_02377 8.1e-252 xynT G MFS/sugar transport protein
KPFMNBKC_02378 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
KPFMNBKC_02379 1.2e-216 xylR GK ROK family
KPFMNBKC_02380 9.2e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KPFMNBKC_02381 3.2e-286 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
KPFMNBKC_02382 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
KPFMNBKC_02386 1.6e-16
KPFMNBKC_02387 8.6e-54 dinB S DinB family
KPFMNBKC_02388 9.7e-186 adhP 1.1.1.1 C alcohol dehydrogenase
KPFMNBKC_02389 3.8e-69 ccmM S Bacterial transferase hexapeptide (six repeats)
KPFMNBKC_02390 1.5e-19 yoaW
KPFMNBKC_02392 3.2e-135 yoaP 3.1.3.18 K YoaP-like
KPFMNBKC_02393 2e-97 J Acetyltransferase (GNAT) domain
KPFMNBKC_02394 1.1e-56
KPFMNBKC_02396 4.2e-112 ynaE S Domain of unknown function (DUF3885)
KPFMNBKC_02397 6e-202 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPFMNBKC_02398 2.6e-117 AA10,CBM73 S Pfam:Chitin_bind_3
KPFMNBKC_02400 6.1e-82 yvgO
KPFMNBKC_02402 0.0 yobO M Pectate lyase superfamily protein
KPFMNBKC_02403 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KPFMNBKC_02404 2.2e-143 yndL S Replication protein
KPFMNBKC_02405 1.6e-07
KPFMNBKC_02406 3.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
KPFMNBKC_02407 4.6e-71 yndM S Protein of unknown function (DUF2512)
KPFMNBKC_02408 2.1e-12 yoaW
KPFMNBKC_02409 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KPFMNBKC_02410 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KPFMNBKC_02411 7.7e-112 yneB L resolvase
KPFMNBKC_02412 9.8e-33 ynzC S UPF0291 protein
KPFMNBKC_02413 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KPFMNBKC_02414 8.3e-81 yneE S Sporulation inhibitor of replication protein sirA
KPFMNBKC_02415 2.3e-28 yneF S UPF0154 protein
KPFMNBKC_02416 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
KPFMNBKC_02417 1.7e-125 ccdA O cytochrome c biogenesis protein
KPFMNBKC_02418 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KPFMNBKC_02419 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KPFMNBKC_02420 2.5e-74 yneK S Protein of unknown function (DUF2621)
KPFMNBKC_02421 3.2e-62 hspX O Spore coat protein
KPFMNBKC_02422 2.3e-19 sspP S Belongs to the SspP family
KPFMNBKC_02423 2.2e-14 sspO S Belongs to the SspO family
KPFMNBKC_02424 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KPFMNBKC_02425 6.3e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KPFMNBKC_02427 2.7e-33 tlp S Belongs to the Tlp family
KPFMNBKC_02428 3.1e-74 yneP S Thioesterase-like superfamily
KPFMNBKC_02429 3.7e-53 yneQ
KPFMNBKC_02430 6.3e-50 yneR S Belongs to the HesB IscA family
KPFMNBKC_02431 1.9e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KPFMNBKC_02432 1.5e-68 yccU S CoA-binding protein
KPFMNBKC_02433 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KPFMNBKC_02434 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KPFMNBKC_02435 4.6e-13
KPFMNBKC_02436 5.1e-41 ynfC
KPFMNBKC_02437 2.7e-250 agcS E Sodium alanine symporter
KPFMNBKC_02438 2.1e-182 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KPFMNBKC_02439 6.5e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
KPFMNBKC_02440 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KPFMNBKC_02441 1.1e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
KPFMNBKC_02442 7e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KPFMNBKC_02443 1.1e-181 kdgR_1 K transcriptional
KPFMNBKC_02444 6.6e-224 exuT G Sugar (and other) transporter
KPFMNBKC_02445 2.3e-153 yndG S DoxX-like family
KPFMNBKC_02446 3.1e-78 yndH S Domain of unknown function (DUF4166)
KPFMNBKC_02447 3.2e-300 yndJ S YndJ-like protein
KPFMNBKC_02448 3.7e-26 yxlH EGP Major facilitator Superfamily
KPFMNBKC_02449 5.9e-216 S Platelet-activating factor acetylhydrolase, isoform II
KPFMNBKC_02451 3.1e-289 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
KPFMNBKC_02452 1.3e-51 S Domain of unknown function (DUF4870)
KPFMNBKC_02453 1e-233 T PhoQ Sensor
KPFMNBKC_02454 3.4e-129 T Transcriptional regulatory protein, C terminal
KPFMNBKC_02455 5.7e-252 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
KPFMNBKC_02456 8e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KPFMNBKC_02457 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_02458 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_02459 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_02460 1.1e-223 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KPFMNBKC_02461 1.2e-138 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KPFMNBKC_02462 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KPFMNBKC_02463 2.4e-124 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KPFMNBKC_02464 6.5e-252 yxjC EG COG2610 H gluconate symporter and related permeases
KPFMNBKC_02465 2e-222 bioI 1.14.14.46 C Cytochrome P450
KPFMNBKC_02466 8.2e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KPFMNBKC_02467 1.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KPFMNBKC_02468 1.3e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KPFMNBKC_02469 2.4e-256 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KPFMNBKC_02470 7.6e-143 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KPFMNBKC_02471 3.7e-72 yngA S membrane
KPFMNBKC_02472 5.5e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KPFMNBKC_02473 3.2e-104 yngC S SNARE associated Golgi protein
KPFMNBKC_02474 1.8e-289 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KPFMNBKC_02475 7.5e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KPFMNBKC_02476 1.4e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KPFMNBKC_02477 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KPFMNBKC_02478 5.5e-253 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KPFMNBKC_02479 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KPFMNBKC_02480 8.3e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KPFMNBKC_02481 9.2e-305 yngK T Glycosyl hydrolase-like 10
KPFMNBKC_02482 1.2e-64 yngL S Protein of unknown function (DUF1360)
KPFMNBKC_02483 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
KPFMNBKC_02484 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_02485 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_02486 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_02487 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_02488 2.4e-270 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KPFMNBKC_02489 9.3e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
KPFMNBKC_02490 1.3e-246 yoeA V MATE efflux family protein
KPFMNBKC_02491 1.9e-95 yoeB S IseA DL-endopeptidase inhibitor
KPFMNBKC_02493 3.5e-97 L Integrase
KPFMNBKC_02494 4.3e-33 yoeD G Helix-turn-helix domain
KPFMNBKC_02495 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KPFMNBKC_02496 3e-199 ybcL EGP Major facilitator Superfamily
KPFMNBKC_02497 1.8e-50 ybzH K Helix-turn-helix domain
KPFMNBKC_02499 1.8e-156 gltR1 K Transcriptional regulator
KPFMNBKC_02500 1e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KPFMNBKC_02501 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KPFMNBKC_02502 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KPFMNBKC_02503 3.3e-153 gltC K Transcriptional regulator
KPFMNBKC_02504 8.7e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KPFMNBKC_02505 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPFMNBKC_02506 1e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KPFMNBKC_02507 5e-75 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
KPFMNBKC_02508 3.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
KPFMNBKC_02509 1.5e-222 K helix_turn_helix, arabinose operon control protein
KPFMNBKC_02510 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KPFMNBKC_02511 3.1e-39 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KPFMNBKC_02512 2.3e-139 yoxB
KPFMNBKC_02513 1.4e-202 yoaB EGP Major facilitator Superfamily
KPFMNBKC_02514 3.6e-274 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
KPFMNBKC_02515 3.8e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPFMNBKC_02516 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KPFMNBKC_02517 1.4e-25 yoaF
KPFMNBKC_02519 1e-99 hpr K helix_turn_helix multiple antibiotic resistance protein
KPFMNBKC_02520 7.1e-44
KPFMNBKC_02521 2.4e-54 S SMI1-KNR4 cell-wall
KPFMNBKC_02522 2.4e-296 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KPFMNBKC_02523 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
KPFMNBKC_02524 7.8e-134 yobQ K helix_turn_helix, arabinose operon control protein
KPFMNBKC_02525 2.2e-94 yobS K Transcriptional regulator
KPFMNBKC_02526 6.1e-134 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
KPFMNBKC_02527 1.9e-92 yobW
KPFMNBKC_02528 3.4e-55 czrA K transcriptional
KPFMNBKC_02529 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KPFMNBKC_02530 1.8e-90 yozB S membrane
KPFMNBKC_02531 6.8e-139 yocB J Protein required for attachment to host cells
KPFMNBKC_02532 2.5e-94 yocC
KPFMNBKC_02533 9.9e-188 yocD 3.4.17.13 V peptidase S66
KPFMNBKC_02535 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
KPFMNBKC_02536 0.0 recQ 3.6.4.12 L DNA helicase
KPFMNBKC_02537 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KPFMNBKC_02539 4.7e-53 dksA T general stress protein
KPFMNBKC_02540 5.9e-10 yocL
KPFMNBKC_02541 1.7e-08
KPFMNBKC_02542 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
KPFMNBKC_02543 1.4e-43 yozN
KPFMNBKC_02544 8.5e-37 yocN
KPFMNBKC_02545 2.4e-56 yozO S Bacterial PH domain
KPFMNBKC_02547 3.6e-31 yozC
KPFMNBKC_02548 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KPFMNBKC_02549 4.1e-303 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KPFMNBKC_02550 4e-33 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KPFMNBKC_02551 3.2e-166 sodA 1.15.1.1 P Superoxide dismutase
KPFMNBKC_02552 3.9e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KPFMNBKC_02553 2.5e-159 yocS S -transporter
KPFMNBKC_02554 3.4e-143 S Metallo-beta-lactamase superfamily
KPFMNBKC_02555 7.2e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KPFMNBKC_02556 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KPFMNBKC_02557 0.0 yojO P Von Willebrand factor
KPFMNBKC_02558 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
KPFMNBKC_02559 5.9e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KPFMNBKC_02560 3.3e-220 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KPFMNBKC_02561 1.9e-225 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
KPFMNBKC_02562 1.8e-110 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KPFMNBKC_02564 9.8e-242 norM V Multidrug efflux pump
KPFMNBKC_02565 1.9e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KPFMNBKC_02566 2.5e-126 yojG S deacetylase
KPFMNBKC_02567 9.7e-61 yojF S Protein of unknown function (DUF1806)
KPFMNBKC_02568 4.9e-23
KPFMNBKC_02569 2e-163 rarD S -transporter
KPFMNBKC_02570 8.6e-81 yozR S COG0071 Molecular chaperone (small heat shock protein)
KPFMNBKC_02572 5.9e-67 yodA S tautomerase
KPFMNBKC_02573 4.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
KPFMNBKC_02574 1.4e-56 yodB K transcriptional
KPFMNBKC_02575 4.5e-106 yodC C nitroreductase
KPFMNBKC_02576 3.6e-95 mhqD S Carboxylesterase
KPFMNBKC_02577 2.2e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
KPFMNBKC_02578 1.4e-19 S Protein of unknown function (DUF3311)
KPFMNBKC_02579 4.6e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KPFMNBKC_02580 1.8e-281 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
KPFMNBKC_02581 6e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KPFMNBKC_02582 6.3e-131 yydK K Transcriptional regulator
KPFMNBKC_02583 2.1e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KPFMNBKC_02584 2.4e-127 yodH Q Methyltransferase
KPFMNBKC_02585 4.3e-34 yodI
KPFMNBKC_02586 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KPFMNBKC_02587 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KPFMNBKC_02589 3.3e-55 yodL S YodL-like
KPFMNBKC_02590 5.2e-102 yodM 3.6.1.27 I Acid phosphatase homologues
KPFMNBKC_02591 6.2e-24 yozD S YozD-like protein
KPFMNBKC_02593 1.7e-125 yodN
KPFMNBKC_02594 4.1e-36 yozE S Belongs to the UPF0346 family
KPFMNBKC_02595 1.3e-44 yokU S YokU-like protein, putative antitoxin
KPFMNBKC_02596 6.1e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
KPFMNBKC_02597 1e-159 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
KPFMNBKC_02598 4.8e-254 yodQ 3.5.1.16 E Acetylornithine deacetylase
KPFMNBKC_02599 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KPFMNBKC_02600 5.8e-126 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KPFMNBKC_02601 5.4e-245 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KPFMNBKC_02602 2e-63 yosT L Bacterial transcription activator, effector binding domain
KPFMNBKC_02604 3.2e-144 yiiD K acetyltransferase
KPFMNBKC_02605 4.5e-249 cgeD M maturation of the outermost layer of the spore
KPFMNBKC_02606 1.6e-52 cgeA
KPFMNBKC_02607 3.3e-180 cgeB S Spore maturation protein
KPFMNBKC_02608 6.1e-221 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
KPFMNBKC_02609 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
KPFMNBKC_02613 9.6e-81
KPFMNBKC_02614 3.4e-65 S Acetyltransferase (GNAT) domain
KPFMNBKC_02615 2.9e-73 yoqH M LysM domain
KPFMNBKC_02616 7.4e-48 S aspartate phosphatase
KPFMNBKC_02617 9.3e-147 S aspartate phosphatase
KPFMNBKC_02619 1.1e-20 1.2.1.9 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KPFMNBKC_02620 4.3e-63
KPFMNBKC_02621 1.4e-62 S SMI1-KNR4 cell-wall
KPFMNBKC_02622 6.3e-207 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KPFMNBKC_02623 5e-12 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KPFMNBKC_02624 1.4e-09 L Belongs to the 'phage' integrase family
KPFMNBKC_02626 1.7e-39 K Putative DNA-binding domain
KPFMNBKC_02627 8.9e-14 S Protein of unknown function (DUF4236)
KPFMNBKC_02632 1.4e-69 yoaW
KPFMNBKC_02634 2.2e-08
KPFMNBKC_02636 4.8e-194 S aspartate phosphatase
KPFMNBKC_02638 6.8e-36 3.4.24.40 S amine dehydrogenase activity
KPFMNBKC_02639 1.1e-74 3.4.24.40 S amine dehydrogenase activity
KPFMNBKC_02642 4.8e-52 S SMI1-KNR4 cell-wall
KPFMNBKC_02643 1.8e-288 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KPFMNBKC_02644 2.1e-77 yokH G SMI1 / KNR4 family
KPFMNBKC_02645 2.7e-76 yokF 3.1.31.1 L RNA catabolic process
KPFMNBKC_02646 4.5e-305 yokA L Recombinase
KPFMNBKC_02647 2.6e-103 4.2.1.115 GM Polysaccharide biosynthesis protein
KPFMNBKC_02648 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KPFMNBKC_02649 7.8e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPFMNBKC_02650 1.4e-66 ypoP K transcriptional
KPFMNBKC_02651 1.6e-97 ypmS S protein conserved in bacteria
KPFMNBKC_02652 1.2e-135 ypmR E GDSL-like Lipase/Acylhydrolase
KPFMNBKC_02653 7.4e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KPFMNBKC_02654 2.6e-39 ypmP S Protein of unknown function (DUF2535)
KPFMNBKC_02655 3.1e-242 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KPFMNBKC_02656 2.6e-175 pspF K Transcriptional regulator
KPFMNBKC_02657 2.7e-109 hlyIII S protein, Hemolysin III
KPFMNBKC_02668 2.7e-140 mta K transcriptional
KPFMNBKC_02669 2.1e-160 yjfC O Predicted Zn-dependent protease (DUF2268)
KPFMNBKC_02670 4.7e-224 ywbD 2.1.1.191 J Methyltransferase
KPFMNBKC_02671 7.6e-67 ywbC 4.4.1.5 E glyoxalase
KPFMNBKC_02672 3.5e-244 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPFMNBKC_02673 1.2e-265 epr 3.4.21.62 O Belongs to the peptidase S8 family
KPFMNBKC_02674 2.8e-162 gspA M General stress
KPFMNBKC_02675 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
KPFMNBKC_02676 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KPFMNBKC_02677 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
KPFMNBKC_02678 2.3e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_02679 3.7e-229 dltB M membrane protein involved in D-alanine export
KPFMNBKC_02680 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_02681 1.5e-227 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KPFMNBKC_02682 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KPFMNBKC_02683 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KPFMNBKC_02684 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KPFMNBKC_02685 2.8e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPFMNBKC_02686 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
KPFMNBKC_02687 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
KPFMNBKC_02688 3.8e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KPFMNBKC_02689 4.3e-173 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPFMNBKC_02690 3.9e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPFMNBKC_02691 3e-167 cbrA3 P Periplasmic binding protein
KPFMNBKC_02692 2.2e-57 arsR K transcriptional
KPFMNBKC_02693 3.8e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KPFMNBKC_02694 1.2e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
KPFMNBKC_02695 3.5e-49 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
KPFMNBKC_02696 1.2e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPFMNBKC_02697 2.1e-287 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KPFMNBKC_02698 2.5e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KPFMNBKC_02699 1.6e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
KPFMNBKC_02700 9.2e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KPFMNBKC_02701 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KPFMNBKC_02702 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KPFMNBKC_02703 1.2e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
KPFMNBKC_02704 5e-156 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KPFMNBKC_02705 5.3e-293 cydD V ATP-binding protein
KPFMNBKC_02706 1.7e-310 cydD V ATP-binding
KPFMNBKC_02707 1.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KPFMNBKC_02708 2.6e-266 cydA 1.10.3.14 C oxidase, subunit
KPFMNBKC_02709 3.8e-214 cimH C COG3493 Na citrate symporter
KPFMNBKC_02710 6e-157 yxkH G Polysaccharide deacetylase
KPFMNBKC_02711 1.6e-205 msmK P Belongs to the ABC transporter superfamily
KPFMNBKC_02712 9.1e-164 lrp QT PucR C-terminal helix-turn-helix domain
KPFMNBKC_02713 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPFMNBKC_02714 4.9e-87 yxkC S Domain of unknown function (DUF4352)
KPFMNBKC_02715 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KPFMNBKC_02716 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KPFMNBKC_02719 2.4e-86 yxjI S LURP-one-related
KPFMNBKC_02720 5.9e-216 yxjG 2.1.1.14 E Methionine synthase
KPFMNBKC_02721 4.8e-157 rlmA 2.1.1.187 Q Methyltransferase domain
KPFMNBKC_02722 2.5e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPFMNBKC_02723 2.7e-75 T Domain of unknown function (DUF4163)
KPFMNBKC_02724 1.4e-50 yxiS
KPFMNBKC_02725 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
KPFMNBKC_02726 1.1e-221 citH C Citrate transporter
KPFMNBKC_02727 1.5e-143 exoK GH16 M licheninase activity
KPFMNBKC_02728 7e-150 licT K transcriptional antiterminator
KPFMNBKC_02729 6e-222 yxiO S COG2270 Permeases of the major facilitator superfamily
KPFMNBKC_02730 4.5e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KPFMNBKC_02733 1.2e-08 S SMI1-KNR4 cell-wall
KPFMNBKC_02734 2.5e-30 S SMI1-KNR4 cell-wall
KPFMNBKC_02735 5e-84 yxiI S Protein of unknown function (DUF2716)
KPFMNBKC_02737 1.7e-20
KPFMNBKC_02738 1.2e-13 S YxiJ-like protein
KPFMNBKC_02741 0.0 wapA M COG3209 Rhs family protein
KPFMNBKC_02742 2.2e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
KPFMNBKC_02743 1.2e-147 yxxF EG EamA-like transporter family
KPFMNBKC_02744 1.3e-73 yxiE T Belongs to the universal stress protein A family
KPFMNBKC_02745 6e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KPFMNBKC_02746 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KPFMNBKC_02747 0.0 L HKD family nuclease
KPFMNBKC_02749 7.2e-55 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KPFMNBKC_02750 1.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KPFMNBKC_02751 3.8e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KPFMNBKC_02752 2.3e-287 hutH 4.3.1.3 E Histidine ammonia-lyase
KPFMNBKC_02753 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KPFMNBKC_02754 2.3e-237 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
KPFMNBKC_02755 5e-176 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KPFMNBKC_02756 1.7e-252 lysP E amino acid
KPFMNBKC_02757 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KPFMNBKC_02758 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPFMNBKC_02759 2.1e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KPFMNBKC_02760 3.3e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KPFMNBKC_02761 4e-150 yidA S hydrolases of the HAD superfamily
KPFMNBKC_02764 6e-11 yxeE
KPFMNBKC_02765 8.4e-23 yxeD
KPFMNBKC_02766 3e-34
KPFMNBKC_02767 1.1e-175 fhuD P Periplasmic binding protein
KPFMNBKC_02768 1.3e-57 yxeA S Protein of unknown function (DUF1093)
KPFMNBKC_02769 0.0 yxdM V ABC transporter (permease)
KPFMNBKC_02770 5.5e-141 yxdL V ABC transporter, ATP-binding protein
KPFMNBKC_02771 5.7e-175 T PhoQ Sensor
KPFMNBKC_02772 1e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPFMNBKC_02773 7.8e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KPFMNBKC_02774 1.7e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KPFMNBKC_02775 9.5e-166 iolH G Xylose isomerase-like TIM barrel
KPFMNBKC_02776 3.6e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KPFMNBKC_02777 5.1e-232 iolF EGP Major facilitator Superfamily
KPFMNBKC_02778 1.4e-175 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KPFMNBKC_02779 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KPFMNBKC_02780 8.3e-182 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KPFMNBKC_02781 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KPFMNBKC_02782 7.9e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KPFMNBKC_02783 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
KPFMNBKC_02784 4.9e-176 iolS C Aldo keto reductase
KPFMNBKC_02785 1.9e-245 csbC EGP Major facilitator Superfamily
KPFMNBKC_02786 0.0 htpG O Molecular chaperone. Has ATPase activity
KPFMNBKC_02788 4.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
KPFMNBKC_02789 6e-103 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KPFMNBKC_02790 8.2e-202 desK 2.7.13.3 T Histidine kinase
KPFMNBKC_02791 4.5e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KPFMNBKC_02792 4.6e-216 yxbF K Bacterial regulatory proteins, tetR family
KPFMNBKC_02793 3.9e-251 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KPFMNBKC_02794 5.2e-141 S PQQ-like domain
KPFMNBKC_02795 9.9e-60 S Family of unknown function (DUF5391)
KPFMNBKC_02796 1.5e-49 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
KPFMNBKC_02797 2.9e-202 EGP Major facilitator Superfamily
KPFMNBKC_02798 8.4e-73 yxaI S membrane protein domain
KPFMNBKC_02799 5.4e-124 E Ring-cleavage extradiol dioxygenase
KPFMNBKC_02800 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KPFMNBKC_02801 2.5e-286 ahpF O Alkyl hydroperoxide reductase
KPFMNBKC_02802 1.9e-228 XK27_00240 S Fic/DOC family
KPFMNBKC_02803 4.2e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
KPFMNBKC_02804 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
KPFMNBKC_02805 6.4e-84 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KPFMNBKC_02806 2.1e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KPFMNBKC_02807 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KPFMNBKC_02808 1.3e-92 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KPFMNBKC_02809 7.2e-189 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KPFMNBKC_02810 3.9e-177 S Fusaric acid resistance protein-like
KPFMNBKC_02811 1.1e-18
KPFMNBKC_02812 0.0 L AAA domain
KPFMNBKC_02813 1.1e-80 F 5-carbamoylmethyl uridine residue modification
KPFMNBKC_02814 1e-94 K NAD+ binding
KPFMNBKC_02815 2.2e-79 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KPFMNBKC_02816 7.9e-08 S YyzF-like protein
KPFMNBKC_02818 1.4e-217 yycP
KPFMNBKC_02819 9.2e-133 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KPFMNBKC_02820 4.8e-182 C oxidoreductases (related to aryl-alcohol dehydrogenases)
KPFMNBKC_02821 1.9e-83 yycN 2.3.1.128 K Acetyltransferase
KPFMNBKC_02823 1.8e-201 S Histidine kinase
KPFMNBKC_02824 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KPFMNBKC_02825 1.5e-258 rocE E amino acid
KPFMNBKC_02826 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KPFMNBKC_02827 2.7e-61 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
KPFMNBKC_02828 2.2e-42 sdpR K transcriptional
KPFMNBKC_02829 1.1e-259 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KPFMNBKC_02830 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
KPFMNBKC_02831 4.8e-304 S ABC transporter
KPFMNBKC_02832 4.5e-195 S Major Facilitator Superfamily
KPFMNBKC_02833 1.6e-260
KPFMNBKC_02834 6.9e-192 2.7.7.73, 2.7.7.80 H ThiF family
KPFMNBKC_02835 3.6e-255 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
KPFMNBKC_02836 4.7e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPFMNBKC_02837 1.2e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KPFMNBKC_02838 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KPFMNBKC_02839 3.2e-150 yycI S protein conserved in bacteria
KPFMNBKC_02840 4.2e-261 yycH S protein conserved in bacteria
KPFMNBKC_02841 0.0 vicK 2.7.13.3 T Histidine kinase
KPFMNBKC_02842 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPFMNBKC_02847 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KPFMNBKC_02848 2.5e-71 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KPFMNBKC_02849 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KPFMNBKC_02850 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
KPFMNBKC_02852 3.5e-17 yycC K YycC-like protein
KPFMNBKC_02853 1.1e-237 M Glycosyltransferase Family 4
KPFMNBKC_02854 4.3e-205 S Ecdysteroid kinase
KPFMNBKC_02855 2.4e-236 S Carbamoyl-phosphate synthase L chain, ATP binding domain
KPFMNBKC_02856 7.3e-242 M Glycosyltransferase Family 4
KPFMNBKC_02857 4.9e-122 S GlcNAc-PI de-N-acetylase
KPFMNBKC_02858 3.4e-123 KLT COG0515 Serine threonine protein kinase
KPFMNBKC_02859 1.4e-72 rplI J binds to the 23S rRNA
KPFMNBKC_02860 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KPFMNBKC_02861 1e-157 yybS S membrane
KPFMNBKC_02863 1.1e-83 cotF M Spore coat protein
KPFMNBKC_02864 4e-65 ydeP3 K Transcriptional regulator
KPFMNBKC_02865 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KPFMNBKC_02866 1.5e-155 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KPFMNBKC_02867 7.7e-274 sacB 2.4.1.10 GH68 M levansucrase activity
KPFMNBKC_02868 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
KPFMNBKC_02869 4.5e-115 K FCD domain
KPFMNBKC_02870 2.4e-76 dinB S PFAM DinB family protein
KPFMNBKC_02871 1.7e-160 G Major Facilitator Superfamily
KPFMNBKC_02872 2.4e-54 ypaA S Protein of unknown function (DUF1304)
KPFMNBKC_02873 5.6e-115 drgA C nitroreductase
KPFMNBKC_02874 5.4e-69 ydgJ K Winged helix DNA-binding domain
KPFMNBKC_02875 2.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KPFMNBKC_02876 5.6e-77 yybA 2.3.1.57 K transcriptional
KPFMNBKC_02877 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
KPFMNBKC_02878 2.3e-164 eaeH M Domain of Unknown Function (DUF1259)
KPFMNBKC_02879 2.3e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
KPFMNBKC_02880 1.2e-163 K Transcriptional regulator
KPFMNBKC_02881 8.6e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KPFMNBKC_02882 9.4e-251 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KPFMNBKC_02883 5.5e-132 ydfC EG EamA-like transporter family
KPFMNBKC_02884 1.9e-30 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KPFMNBKC_02885 4e-81
KPFMNBKC_02886 3.9e-69 ynaF
KPFMNBKC_02888 4.2e-250 KLT Protein tyrosine kinase
KPFMNBKC_02889 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KPFMNBKC_02890 1.2e-160 yyaK S CAAX protease self-immunity
KPFMNBKC_02891 2.6e-247 ydjK G Sugar (and other) transporter
KPFMNBKC_02892 1.3e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KPFMNBKC_02893 4.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
KPFMNBKC_02894 7.6e-143 xth 3.1.11.2 L exodeoxyribonuclease III
KPFMNBKC_02895 2.4e-101 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KPFMNBKC_02896 3.7e-105 adaA 3.2.2.21 K Transcriptional regulator
KPFMNBKC_02897 1.1e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KPFMNBKC_02898 4.2e-68 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KPFMNBKC_02899 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
KPFMNBKC_02900 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KPFMNBKC_02901 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KPFMNBKC_02902 2.3e-33 yyzM S protein conserved in bacteria
KPFMNBKC_02903 3.1e-176 yyaD S Membrane
KPFMNBKC_02904 8.4e-82 4.2.1.103 K FR47-like protein
KPFMNBKC_02905 6.2e-111 yyaC S Sporulation protein YyaC
KPFMNBKC_02906 1.8e-148 spo0J K Belongs to the ParB family
KPFMNBKC_02907 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
KPFMNBKC_02908 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KPFMNBKC_02909 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KPFMNBKC_02910 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KPFMNBKC_02911 1.2e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KPFMNBKC_02912 1e-108 jag S single-stranded nucleic acid binding R3H
KPFMNBKC_02913 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KPFMNBKC_02914 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KPFMNBKC_02915 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KPFMNBKC_02916 7.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KPFMNBKC_02917 2.4e-33 yaaA S S4 domain
KPFMNBKC_02918 4.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KPFMNBKC_02919 1.1e-37 yaaB S Domain of unknown function (DUF370)
KPFMNBKC_02920 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPFMNBKC_02921 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPFMNBKC_02922 1.6e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KPFMNBKC_02923 4.8e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KPFMNBKC_02924 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KPFMNBKC_02925 2.7e-114 ypjP S YpjP-like protein
KPFMNBKC_02926 2.6e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
KPFMNBKC_02927 1e-75 yphP S Belongs to the UPF0403 family
KPFMNBKC_02928 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KPFMNBKC_02929 1.5e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
KPFMNBKC_02930 7e-99 ypgQ S phosphohydrolase
KPFMNBKC_02931 1.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KPFMNBKC_02932 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KPFMNBKC_02933 5.5e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KPFMNBKC_02934 7.9e-31 cspD K Cold-shock protein
KPFMNBKC_02935 1.3e-11 degR
KPFMNBKC_02936 1.2e-36 S Protein of unknown function (DUF2564)
KPFMNBKC_02937 1.5e-28 ypeQ S Zinc-finger
KPFMNBKC_02938 5.3e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
KPFMNBKC_02939 1.2e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KPFMNBKC_02940 4.2e-68 rnhA 3.1.26.4 L Ribonuclease
KPFMNBKC_02942 3.5e-163 polA 2.7.7.7 L 5'3' exonuclease
KPFMNBKC_02944 1e-38 ypbS S Protein of unknown function (DUF2533)
KPFMNBKC_02945 0.0 ypbR S Dynamin family
KPFMNBKC_02946 1.4e-89 ypbQ S protein conserved in bacteria
KPFMNBKC_02947 2e-205 bcsA Q Naringenin-chalcone synthase
KPFMNBKC_02948 1.5e-104 J Acetyltransferase (GNAT) domain
KPFMNBKC_02949 6.2e-51 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
KPFMNBKC_02951 2.2e-97 ydfR S Protein of unknown function (DUF421)
KPFMNBKC_02952 1.3e-99 yrdC 3.5.1.19 Q Isochorismatase family
KPFMNBKC_02954 4.2e-234 pbuX F xanthine
KPFMNBKC_02955 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KPFMNBKC_02956 4.3e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KPFMNBKC_02957 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
KPFMNBKC_02959 6.6e-22 S YpzG-like protein
KPFMNBKC_02960 5.1e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KPFMNBKC_02961 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KPFMNBKC_02962 4.8e-99 ypsA S Belongs to the UPF0398 family
KPFMNBKC_02963 9.9e-33 cotD S Inner spore coat protein D
KPFMNBKC_02965 1.5e-236 yprB L RNase_H superfamily
KPFMNBKC_02966 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KPFMNBKC_02967 1.1e-86 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KPFMNBKC_02968 3.8e-72 hspX O Belongs to the small heat shock protein (HSP20) family
KPFMNBKC_02969 4.5e-45 yppG S YppG-like protein
KPFMNBKC_02971 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
KPFMNBKC_02974 1.1e-186 yppC S Protein of unknown function (DUF2515)
KPFMNBKC_02975 8e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KPFMNBKC_02976 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KPFMNBKC_02977 4.3e-91 ypoC
KPFMNBKC_02978 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KPFMNBKC_02979 6.8e-130 dnaD L DNA replication protein DnaD
KPFMNBKC_02980 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
KPFMNBKC_02981 9.7e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KPFMNBKC_02982 1.2e-80 ypmB S protein conserved in bacteria
KPFMNBKC_02983 6.7e-23 ypmA S Protein of unknown function (DUF4264)
KPFMNBKC_02984 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KPFMNBKC_02985 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KPFMNBKC_02986 6.5e-159 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KPFMNBKC_02987 7e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KPFMNBKC_02988 9.6e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KPFMNBKC_02989 2.8e-216 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KPFMNBKC_02990 1.1e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KPFMNBKC_02991 1.9e-132 bshB1 S proteins, LmbE homologs
KPFMNBKC_02992 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KPFMNBKC_02993 5.9e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KPFMNBKC_02994 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KPFMNBKC_02995 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KPFMNBKC_02996 1.9e-225 oxdC 4.1.1.2 G Oxalate decarboxylase
KPFMNBKC_02997 5.1e-142 ypjB S sporulation protein
KPFMNBKC_02998 4.1e-104 ypjA S membrane
KPFMNBKC_02999 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KPFMNBKC_03000 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
KPFMNBKC_03001 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
KPFMNBKC_03002 3.2e-77 ypiF S Protein of unknown function (DUF2487)
KPFMNBKC_03003 2.1e-99 ypiB S Belongs to the UPF0302 family
KPFMNBKC_03004 7.7e-233 S COG0457 FOG TPR repeat
KPFMNBKC_03005 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KPFMNBKC_03006 2e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KPFMNBKC_03007 1.5e-200 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KPFMNBKC_03008 2.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KPFMNBKC_03009 6.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KPFMNBKC_03010 4e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
KPFMNBKC_03011 2.5e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KPFMNBKC_03012 3.1e-160 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KPFMNBKC_03013 1.2e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KPFMNBKC_03014 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KPFMNBKC_03015 1.6e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KPFMNBKC_03016 1.4e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KPFMNBKC_03017 1.4e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KPFMNBKC_03018 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KPFMNBKC_03019 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KPFMNBKC_03020 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KPFMNBKC_03021 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KPFMNBKC_03022 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KPFMNBKC_03023 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
KPFMNBKC_03024 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KPFMNBKC_03025 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KPFMNBKC_03026 1.6e-134 yphF
KPFMNBKC_03027 3.3e-16 yphE S Protein of unknown function (DUF2768)
KPFMNBKC_03028 1.5e-189 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KPFMNBKC_03029 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KPFMNBKC_03030 1.1e-104 yphA
KPFMNBKC_03031 4.7e-08 S YpzI-like protein
KPFMNBKC_03032 1.5e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KPFMNBKC_03033 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
KPFMNBKC_03034 1.6e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KPFMNBKC_03035 1.4e-12 S Family of unknown function (DUF5359)
KPFMNBKC_03036 1.3e-61 ypfA M Flagellar protein YcgR
KPFMNBKC_03037 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KPFMNBKC_03038 4.2e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KPFMNBKC_03039 9.2e-121 prsW S Involved in the degradation of specific anti-sigma factors
KPFMNBKC_03040 4.5e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KPFMNBKC_03041 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KPFMNBKC_03042 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KPFMNBKC_03043 1.6e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
KPFMNBKC_03044 5.7e-85 ypbF S Protein of unknown function (DUF2663)
KPFMNBKC_03045 3.4e-74 ypbE M Lysin motif
KPFMNBKC_03046 2.2e-99 ypbD S metal-dependent membrane protease
KPFMNBKC_03047 5.2e-270 recQ 3.6.4.12 L DNA helicase
KPFMNBKC_03048 2.4e-195 ypbB 5.1.3.1 S protein conserved in bacteria
KPFMNBKC_03049 3.6e-41 fer C Ferredoxin
KPFMNBKC_03050 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KPFMNBKC_03051 2.8e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPFMNBKC_03052 7e-198 rsiX
KPFMNBKC_03053 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
KPFMNBKC_03054 0.0 resE 2.7.13.3 T Histidine kinase
KPFMNBKC_03055 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPFMNBKC_03056 1.9e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KPFMNBKC_03057 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KPFMNBKC_03058 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KPFMNBKC_03059 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KPFMNBKC_03060 2.2e-88 spmB S Spore maturation protein
KPFMNBKC_03061 2e-103 spmA S Spore maturation protein
KPFMNBKC_03062 5e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KPFMNBKC_03063 3.8e-93 ypuI S Protein of unknown function (DUF3907)
KPFMNBKC_03064 5.1e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KPFMNBKC_03065 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KPFMNBKC_03067 8.4e-93 ypuF S Domain of unknown function (DUF309)
KPFMNBKC_03068 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KPFMNBKC_03069 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KPFMNBKC_03070 2.7e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KPFMNBKC_03071 2.2e-111 ribE 2.5.1.9 H Riboflavin synthase
KPFMNBKC_03072 2.8e-210 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KPFMNBKC_03073 1.7e-49 ypuD
KPFMNBKC_03074 1.3e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KPFMNBKC_03075 8.2e-82 ccdC1 O Protein of unknown function (DUF1453)
KPFMNBKC_03076 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KPFMNBKC_03077 6e-155 ypuA S Secreted protein
KPFMNBKC_03078 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KPFMNBKC_03079 7.1e-270 spoVAF EG Stage V sporulation protein AF
KPFMNBKC_03080 1.8e-110 spoVAEA S stage V sporulation protein
KPFMNBKC_03081 3.8e-57 spoVAEB S stage V sporulation protein
KPFMNBKC_03082 5e-190 spoVAD I Stage V sporulation protein AD
KPFMNBKC_03083 6e-79 spoVAC S stage V sporulation protein AC
KPFMNBKC_03084 3.9e-60 spoVAB S Stage V sporulation protein AB
KPFMNBKC_03085 3.7e-111 spoVAA S Stage V sporulation protein AA
KPFMNBKC_03086 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KPFMNBKC_03087 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KPFMNBKC_03088 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KPFMNBKC_03089 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KPFMNBKC_03090 6.4e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KPFMNBKC_03091 6.7e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KPFMNBKC_03092 3.7e-165 xerD L recombinase XerD
KPFMNBKC_03093 3.7e-37 S Protein of unknown function (DUF4227)
KPFMNBKC_03094 1.9e-80 fur P Belongs to the Fur family
KPFMNBKC_03095 7.2e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KPFMNBKC_03097 1.7e-34 yqkK
KPFMNBKC_03098 5.7e-22
KPFMNBKC_03099 7.7e-244 mleA 1.1.1.38 C malic enzyme
KPFMNBKC_03100 1.2e-239 mleN C Na H antiporter
KPFMNBKC_03101 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
KPFMNBKC_03102 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
KPFMNBKC_03103 3.5e-58 ansR K Transcriptional regulator
KPFMNBKC_03104 1.4e-217 yqxK 3.6.4.12 L DNA helicase
KPFMNBKC_03105 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KPFMNBKC_03107 2.2e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KPFMNBKC_03109 4.3e-177 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KPFMNBKC_03110 3.2e-39 yqkC S Protein of unknown function (DUF2552)
KPFMNBKC_03111 7.7e-61 yqkB S Belongs to the HesB IscA family
KPFMNBKC_03112 1.1e-175 yqkA K GrpB protein
KPFMNBKC_03113 4.7e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
KPFMNBKC_03114 3.3e-88 yqjY K acetyltransferase
KPFMNBKC_03115 2.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPFMNBKC_03116 7.6e-58 S YolD-like protein
KPFMNBKC_03118 6e-186 yueF S transporter activity
KPFMNBKC_03120 6.6e-74 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KPFMNBKC_03121 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
KPFMNBKC_03122 2.8e-257 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
KPFMNBKC_03123 1.9e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KPFMNBKC_03124 1.3e-176 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
KPFMNBKC_03125 2.1e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPFMNBKC_03126 9.7e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KPFMNBKC_03127 2.1e-238 pksG 2.3.3.10 I synthase
KPFMNBKC_03128 8.9e-220 eryK 1.14.13.154 C Cytochrome P450
KPFMNBKC_03129 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KPFMNBKC_03130 0.0 Q Polyketide synthase of type I
KPFMNBKC_03131 0.0 pfaA Q Polyketide synthase of type I
KPFMNBKC_03132 0.0 pksJ Q Polyketide synthase of type I
KPFMNBKC_03133 2.2e-76 yclD
KPFMNBKC_03134 2e-38 bsdD 4.1.1.61 S response to toxic substance
KPFMNBKC_03135 2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KPFMNBKC_03136 7.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KPFMNBKC_03137 1.5e-158 bsdA K LysR substrate binding domain
KPFMNBKC_03138 1.4e-142 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KPFMNBKC_03139 1.4e-119 tcyB P COG0765 ABC-type amino acid transport system, permease component
KPFMNBKC_03140 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KPFMNBKC_03141 2.8e-111 yczE S membrane
KPFMNBKC_03142 6.5e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
KPFMNBKC_03143 8.2e-246 ycxD K GntR family transcriptional regulator
KPFMNBKC_03144 1.3e-168 ycxC EG EamA-like transporter family
KPFMNBKC_03145 3.8e-64 S YcxB-like protein
KPFMNBKC_03146 2.7e-249 bamJ E Aminotransferase class I and II
KPFMNBKC_03147 3.4e-140 srfAD Q thioesterase
KPFMNBKC_03148 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
KPFMNBKC_03149 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_03150 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_03151 6.3e-63 hxlR K transcriptional
KPFMNBKC_03152 2.8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
KPFMNBKC_03153 1.1e-93 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
KPFMNBKC_03154 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
KPFMNBKC_03155 2.9e-69 nin S Competence protein J (ComJ)
KPFMNBKC_03156 2.2e-34 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KPFMNBKC_03157 2.2e-51 S Protein of unknown function (DUF2680)
KPFMNBKC_03158 4.7e-73 yckC S membrane
KPFMNBKC_03159 4.6e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KPFMNBKC_03160 1.6e-227 yciC S GTPases (G3E family)
KPFMNBKC_03161 1.2e-222 nasA P COG2223 Nitrate nitrite transporter
KPFMNBKC_03162 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
KPFMNBKC_03163 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KPFMNBKC_03164 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KPFMNBKC_03165 3.9e-56 nirD 1.7.1.15 P Nitrite reductase
KPFMNBKC_03166 9.9e-277 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KPFMNBKC_03167 3.5e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KPFMNBKC_03168 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
KPFMNBKC_03169 2.9e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KPFMNBKC_03170 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KPFMNBKC_03171 2.3e-170 ycgM E Proline dehydrogenase
KPFMNBKC_03172 5.9e-143 ycgL S Predicted nucleotidyltransferase
KPFMNBKC_03173 4.5e-185 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KPFMNBKC_03174 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KPFMNBKC_03175 9.1e-221 G COG0477 Permeases of the major facilitator superfamily
KPFMNBKC_03176 1.9e-136 4.2.1.118 G Xylose isomerase-like TIM barrel
KPFMNBKC_03178 1.8e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KPFMNBKC_03179 7.6e-114 ycgI S Domain of unknown function (DUF1989)
KPFMNBKC_03180 8.3e-246 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KPFMNBKC_03181 2.9e-150 yqcI S YqcI/YcgG family
KPFMNBKC_03182 4.7e-114 ycgF E Lysine exporter protein LysE YggA
KPFMNBKC_03183 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
KPFMNBKC_03184 1.5e-259 mdr EGP Major facilitator Superfamily
KPFMNBKC_03185 5.7e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KPFMNBKC_03186 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
KPFMNBKC_03187 3.1e-81 ycgB
KPFMNBKC_03188 4e-230 ycgA S Membrane
KPFMNBKC_03189 3.1e-209 amhX S amidohydrolase
KPFMNBKC_03190 3.1e-164 opuAC E glycine betaine
KPFMNBKC_03191 1.6e-138 opuAB P glycine betaine
KPFMNBKC_03192 4.3e-228 proV 3.6.3.32 E glycine betaine
KPFMNBKC_03193 1.8e-215 naiP P Uncharacterised MFS-type transporter YbfB
KPFMNBKC_03194 5.1e-193 yceH P Belongs to the TelA family
KPFMNBKC_03195 0.0 yceG S Putative component of 'biosynthetic module'
KPFMNBKC_03196 9.7e-138 terC P Protein of unknown function (DUF475)
KPFMNBKC_03197 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
KPFMNBKC_03198 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
KPFMNBKC_03199 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
KPFMNBKC_03200 3.3e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPFMNBKC_03201 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KPFMNBKC_03202 5.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KPFMNBKC_03203 7.9e-164 adcA P Belongs to the bacterial solute-binding protein 9 family
KPFMNBKC_03204 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KPFMNBKC_03205 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
KPFMNBKC_03206 6e-189 S response regulator aspartate phosphatase
KPFMNBKC_03207 4e-92 cwlK M D-alanyl-D-alanine carboxypeptidase
KPFMNBKC_03208 7.7e-263 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
KPFMNBKC_03209 1.2e-258 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
KPFMNBKC_03210 1e-176 ycdA S Domain of unknown function (DUF5105)
KPFMNBKC_03211 6.2e-171 yccK C Aldo keto reductase
KPFMNBKC_03212 5.4e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
KPFMNBKC_03213 1.3e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KPFMNBKC_03214 1.1e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KPFMNBKC_03215 1.2e-100 yxaF K Transcriptional regulator
KPFMNBKC_03216 1e-241 lmrB EGP the major facilitator superfamily
KPFMNBKC_03217 4.2e-206 ycbU E Selenocysteine lyase
KPFMNBKC_03218 1.6e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KPFMNBKC_03219 1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KPFMNBKC_03220 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KPFMNBKC_03221 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
KPFMNBKC_03222 5.1e-80 sleB 3.5.1.28 M Cell wall
KPFMNBKC_03223 5.6e-62 ycbP S Protein of unknown function (DUF2512)
KPFMNBKC_03224 4.1e-56 traF CO Thioredoxin
KPFMNBKC_03225 1.5e-62 mhqP S DoxX
KPFMNBKC_03226 3.2e-183 ydfO E COG0346 Lactoylglutathione lyase and related lyases
KPFMNBKC_03227 2.4e-110 ydfN C nitroreductase
KPFMNBKC_03228 4.5e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPFMNBKC_03229 2.7e-29 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
KPFMNBKC_03230 9.1e-170 glnL T Regulator
KPFMNBKC_03231 8.5e-211 phoQ 2.7.13.3 T Histidine kinase
KPFMNBKC_03232 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
KPFMNBKC_03233 9.3e-259 agcS E Sodium alanine symporter
KPFMNBKC_03234 2.8e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
KPFMNBKC_03235 6.8e-257 mmuP E amino acid
KPFMNBKC_03236 8.6e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KPFMNBKC_03237 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KPFMNBKC_03238 2.3e-192 yceA S Belongs to the UPF0176 family
KPFMNBKC_03239 8e-42 ybfN
KPFMNBKC_03240 1.9e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KPFMNBKC_03241 1.9e-86 ybfM S SNARE associated Golgi protein
KPFMNBKC_03242 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KPFMNBKC_03243 6.2e-213 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KPFMNBKC_03244 8.6e-201 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KPFMNBKC_03245 1.8e-81 K Helix-turn-helix XRE-family like proteins
KPFMNBKC_03246 1.3e-30
KPFMNBKC_03247 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
KPFMNBKC_03249 1.5e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
KPFMNBKC_03250 1.3e-16 S Protein of unknown function (DUF2651)
KPFMNBKC_03251 1.7e-259 glpT G -transporter
KPFMNBKC_03252 2.4e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KPFMNBKC_03253 3.4e-15 S Protein of unknown function (DUF2651)
KPFMNBKC_03254 1e-53
KPFMNBKC_03255 1.2e-291 ybeC E amino acid
KPFMNBKC_03256 9.2e-40 ybyB
KPFMNBKC_03257 1.4e-106 yqeB
KPFMNBKC_03258 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
KPFMNBKC_03259 4.5e-77 S Domain of unknown function (DUF4879)
KPFMNBKC_03260 5.8e-25
KPFMNBKC_03261 2.9e-199 V ABC-2 family transporter protein
KPFMNBKC_03262 4.9e-205 V COG0842 ABC-type multidrug transport system, permease component
KPFMNBKC_03263 5.4e-167 V COG1131 ABC-type multidrug transport system, ATPase component
KPFMNBKC_03264 2.3e-108 KT LuxR family transcriptional regulator
KPFMNBKC_03265 1.1e-201 T COG4585 Signal transduction histidine kinase
KPFMNBKC_03266 9.4e-95 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KPFMNBKC_03267 8.9e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KPFMNBKC_03269 8.8e-72 yxaD K helix_turn_helix multiple antibiotic resistance protein
KPFMNBKC_03270 6.9e-52 S LrgA family
KPFMNBKC_03271 1e-93 yxaC M effector of murein hydrolase
KPFMNBKC_03272 4.3e-163 dkgB S Aldo/keto reductase family
KPFMNBKC_03273 4.9e-133 ybdO S Domain of unknown function (DUF4885)
KPFMNBKC_03274 4.4e-97 ybdN
KPFMNBKC_03275 1.9e-06
KPFMNBKC_03276 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KPFMNBKC_03277 4.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KPFMNBKC_03278 2.6e-224 ybbR S protein conserved in bacteria
KPFMNBKC_03279 1.3e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KPFMNBKC_03280 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KPFMNBKC_03281 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KPFMNBKC_03287 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
KPFMNBKC_03288 1.1e-86 ybbJ J acetyltransferase
KPFMNBKC_03289 2e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KPFMNBKC_03290 1.1e-237 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KPFMNBKC_03291 1.4e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
KPFMNBKC_03292 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KPFMNBKC_03293 7.8e-238 ybbC 3.2.1.52 S protein conserved in bacteria
KPFMNBKC_03294 2.2e-311 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
KPFMNBKC_03295 1.1e-170 feuA P Iron-uptake system-binding protein
KPFMNBKC_03296 6.2e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPFMNBKC_03297 8e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPFMNBKC_03298 2.8e-102 ybbA S Putative esterase
KPFMNBKC_03299 9.7e-175 ybaS 1.1.1.58 S Na -dependent transporter
KPFMNBKC_03300 1.9e-224 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
KPFMNBKC_03301 4.2e-200 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
KPFMNBKC_03302 2.5e-180 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
KPFMNBKC_03303 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KPFMNBKC_03304 9.3e-220 glcP G Major Facilitator Superfamily
KPFMNBKC_03305 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPFMNBKC_03306 0.0 Q Polyketide synthase of type I
KPFMNBKC_03307 6.1e-202 K helix_turn_helix, Arsenical Resistance Operon Repressor
KPFMNBKC_03308 0.0 IQ AMP-binding enzyme
KPFMNBKC_03309 7.4e-40 ytzC S Protein of unknown function (DUF2524)
KPFMNBKC_03311 3.9e-66 ytrA K GntR family transcriptional regulator
KPFMNBKC_03312 3.8e-162 ytrB P abc transporter atp-binding protein
KPFMNBKC_03313 6.5e-171 S ABC-2 family transporter protein
KPFMNBKC_03314 6.3e-166 P ABC-2 family transporter protein
KPFMNBKC_03315 2.9e-147
KPFMNBKC_03316 2.2e-125 ytrE V ABC transporter, ATP-binding protein
KPFMNBKC_03317 1.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
KPFMNBKC_03318 2e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPFMNBKC_03319 1e-171 T PhoQ Sensor
KPFMNBKC_03320 9.8e-135 bceA V ABC transporter, ATP-binding protein
KPFMNBKC_03321 0.0 bceB V ABC transporter (permease)
KPFMNBKC_03322 7.2e-127 ywaF S Integral membrane protein
KPFMNBKC_03323 2.2e-205 yttB EGP Major facilitator Superfamily
KPFMNBKC_03324 3.4e-138 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KPFMNBKC_03325 1.2e-52 ytvB S Protein of unknown function (DUF4257)
KPFMNBKC_03326 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPFMNBKC_03327 1.8e-50 ytwF P Sulfurtransferase
KPFMNBKC_03328 4.3e-26 M Acetyltransferase (GNAT) domain
KPFMNBKC_03329 2.2e-47 M Acetyltransferase (GNAT) domain
KPFMNBKC_03330 2.9e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KPFMNBKC_03331 9e-142 amyC P ABC transporter (permease)
KPFMNBKC_03332 5.3e-167 amyD G Binding-protein-dependent transport system inner membrane component
KPFMNBKC_03333 4.4e-244 msmE G Bacterial extracellular solute-binding protein
KPFMNBKC_03334 1.8e-184 msmR K Transcriptional regulator
KPFMNBKC_03335 9e-26 yteV S Sporulation protein Cse60
KPFMNBKC_03336 6.4e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KPFMNBKC_03337 3.3e-236 ytfP S HI0933-like protein
KPFMNBKC_03338 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KPFMNBKC_03339 8.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KPFMNBKC_03340 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KPFMNBKC_03341 7.5e-129 ythP V ABC transporter
KPFMNBKC_03342 2.3e-215 ythQ U Bacterial ABC transporter protein EcsB
KPFMNBKC_03343 2.6e-228 pbuO S permease
KPFMNBKC_03344 2.1e-268 pepV 3.5.1.18 E Dipeptidase
KPFMNBKC_03345 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KPFMNBKC_03346 5.2e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KPFMNBKC_03347 1.8e-170 ytlQ
KPFMNBKC_03348 2.6e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KPFMNBKC_03349 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
KPFMNBKC_03350 1.3e-44 ytzH S YtzH-like protein
KPFMNBKC_03351 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KPFMNBKC_03352 8.7e-164 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KPFMNBKC_03353 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
KPFMNBKC_03354 1.7e-51 ytzB S small secreted protein
KPFMNBKC_03355 2.2e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KPFMNBKC_03356 3.7e-65 S Putative stress-induced transcription regulator
KPFMNBKC_03357 1.4e-69 T HPP family
KPFMNBKC_03358 1.7e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
KPFMNBKC_03359 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KPFMNBKC_03360 1.4e-147 ytpQ S Belongs to the UPF0354 family
KPFMNBKC_03361 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KPFMNBKC_03362 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KPFMNBKC_03363 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KPFMNBKC_03364 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KPFMNBKC_03365 1.7e-16 ytxH S COG4980 Gas vesicle protein
KPFMNBKC_03366 4.5e-44 ytxJ O Protein of unknown function (DUF2847)
KPFMNBKC_03367 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KPFMNBKC_03368 6.4e-182 ccpA K catabolite control protein A
KPFMNBKC_03369 2.5e-144 motA N flagellar motor
KPFMNBKC_03370 3.7e-120 motS N Flagellar motor protein
KPFMNBKC_03371 1.9e-230 acuC BQ histone deacetylase
KPFMNBKC_03372 9.3e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
KPFMNBKC_03373 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KPFMNBKC_03374 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KPFMNBKC_03375 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KPFMNBKC_03376 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
KPFMNBKC_03377 2.6e-124 azlC E AzlC protein
KPFMNBKC_03378 5.7e-149 K Transcriptional regulator
KPFMNBKC_03379 1.9e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPFMNBKC_03380 3.5e-140 E GDSL-like Lipase/Acylhydrolase family
KPFMNBKC_03382 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
KPFMNBKC_03383 2.5e-09
KPFMNBKC_03384 4.1e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KPFMNBKC_03385 8.2e-59 UW Hep Hag repeat protein
KPFMNBKC_03386 2.9e-10 V HNH endonuclease
KPFMNBKC_03387 6.4e-99 yokH G SMI1 / KNR4 family
KPFMNBKC_03388 3.5e-255 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KPFMNBKC_03389 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KPFMNBKC_03390 5.6e-282 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KPFMNBKC_03391 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
KPFMNBKC_03392 7.7e-109 yttP K Transcriptional regulator
KPFMNBKC_03393 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KPFMNBKC_03394 1.1e-263 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KPFMNBKC_03395 3.1e-240 braB E Component of the transport system for branched-chain amino acids
KPFMNBKC_03396 2.7e-208 iscS2 2.8.1.7 E Cysteine desulfurase
KPFMNBKC_03397 3.9e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPFMNBKC_03398 3.9e-31 sspB S spore protein
KPFMNBKC_03399 1.6e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KPFMNBKC_03400 0.0 ytcJ S amidohydrolase
KPFMNBKC_03401 5.7e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KPFMNBKC_03402 1.1e-181 sppA OU signal peptide peptidase SppA
KPFMNBKC_03403 4.5e-88 yteJ S RDD family
KPFMNBKC_03404 1.4e-108 ytfI S Protein of unknown function (DUF2953)
KPFMNBKC_03405 1.6e-60 ytfJ S Sporulation protein YtfJ
KPFMNBKC_03406 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KPFMNBKC_03407 3.7e-182 ytxK 2.1.1.72 L DNA methylase
KPFMNBKC_03408 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KPFMNBKC_03409 2.3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KPFMNBKC_03410 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KPFMNBKC_03411 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
KPFMNBKC_03413 4.5e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KPFMNBKC_03414 1.1e-129 ytkL S Belongs to the UPF0173 family
KPFMNBKC_03415 2.8e-238 ytoI K transcriptional regulator containing CBS domains
KPFMNBKC_03416 1.5e-46 ytpI S YtpI-like protein
KPFMNBKC_03417 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KPFMNBKC_03418 4.4e-23
KPFMNBKC_03419 5.1e-87 ytrI
KPFMNBKC_03420 3.2e-56 ytrH S Sporulation protein YtrH
KPFMNBKC_03421 0.0 dnaE 2.7.7.7 L DNA polymerase
KPFMNBKC_03422 2.6e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
KPFMNBKC_03423 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KPFMNBKC_03424 2.4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KPFMNBKC_03425 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KPFMNBKC_03426 6.4e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KPFMNBKC_03427 2.1e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
KPFMNBKC_03428 2.4e-193 ytvI S sporulation integral membrane protein YtvI
KPFMNBKC_03429 2.5e-72 yeaL S membrane
KPFMNBKC_03430 1.1e-47 yjdF S Protein of unknown function (DUF2992)
KPFMNBKC_03431 2.7e-52
KPFMNBKC_03432 3.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
KPFMNBKC_03433 3.1e-242 icd 1.1.1.42 C isocitrate
KPFMNBKC_03434 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KPFMNBKC_03435 3.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPFMNBKC_03436 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KPFMNBKC_03437 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPFMNBKC_03438 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KPFMNBKC_03439 9.5e-107 ytaF P Probably functions as a manganese efflux pump
KPFMNBKC_03440 5.2e-99 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPFMNBKC_03441 7.6e-160 ytbE S reductase
KPFMNBKC_03442 1.7e-205 ytbD EGP Major facilitator Superfamily
KPFMNBKC_03443 2e-67 ytcD K Transcriptional regulator
KPFMNBKC_03444 8.8e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KPFMNBKC_03445 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KPFMNBKC_03446 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KPFMNBKC_03447 5.9e-250 dnaB L Membrane attachment protein
KPFMNBKC_03448 9.5e-172 dnaI L Primosomal protein DnaI
KPFMNBKC_03449 3.3e-107 ytxB S SNARE associated Golgi protein
KPFMNBKC_03450 4.4e-152 ytxC S YtxC-like family
KPFMNBKC_03451 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KPFMNBKC_03452 1e-150 ysaA S HAD-hyrolase-like
KPFMNBKC_03453 0.0 lytS 2.7.13.3 T Histidine kinase
KPFMNBKC_03454 1.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
KPFMNBKC_03455 9.1e-40 lrgA S effector of murein hydrolase LrgA
KPFMNBKC_03456 1.1e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KPFMNBKC_03457 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KPFMNBKC_03458 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KPFMNBKC_03459 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KPFMNBKC_03460 7e-43 ysdA S Membrane
KPFMNBKC_03461 1.7e-66 ysdB S Sigma-w pathway protein YsdB
KPFMNBKC_03462 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
KPFMNBKC_03463 4.4e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KPFMNBKC_03464 3.4e-296 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KPFMNBKC_03465 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
KPFMNBKC_03466 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KPFMNBKC_03467 1.2e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KPFMNBKC_03468 1.3e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KPFMNBKC_03469 1.8e-253 araN G carbohydrate transport
KPFMNBKC_03470 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
KPFMNBKC_03471 1.2e-144 araQ G transport system permease
KPFMNBKC_03472 3.9e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
KPFMNBKC_03473 0.0 cstA T Carbon starvation protein
KPFMNBKC_03474 3.4e-255 glcF C Glycolate oxidase
KPFMNBKC_03475 8.2e-260 glcD 1.1.3.15 C FAD binding domain
KPFMNBKC_03476 2.4e-206 ysfB KT regulator
KPFMNBKC_03477 2e-32 sspI S Belongs to the SspI family
KPFMNBKC_03478 2e-132 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPFMNBKC_03479 1.2e-194 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KPFMNBKC_03480 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KPFMNBKC_03481 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPFMNBKC_03482 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KPFMNBKC_03483 1.6e-83 cvpA S membrane protein, required for colicin V production
KPFMNBKC_03484 0.0 polX L COG1796 DNA polymerase IV (family X)
KPFMNBKC_03485 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KPFMNBKC_03486 4.7e-67 yshE S membrane
KPFMNBKC_03488 3.5e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KPFMNBKC_03491 5.7e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPFMNBKC_03492 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KPFMNBKC_03493 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
KPFMNBKC_03494 1e-304 recN L May be involved in recombinational repair of damaged DNA
KPFMNBKC_03495 3.9e-78 argR K Regulates arginine biosynthesis genes
KPFMNBKC_03496 7.3e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KPFMNBKC_03497 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KPFMNBKC_03498 8.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KPFMNBKC_03499 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPFMNBKC_03500 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPFMNBKC_03501 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KPFMNBKC_03502 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPFMNBKC_03503 8.1e-67 yqhY S protein conserved in bacteria
KPFMNBKC_03504 2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KPFMNBKC_03505 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KPFMNBKC_03506 2.5e-62 spoIIIAH S SpoIIIAH-like protein
KPFMNBKC_03507 7.7e-118 spoIIIAG S stage III sporulation protein AG
KPFMNBKC_03508 2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
KPFMNBKC_03509 6.3e-200 spoIIIAE S stage III sporulation protein AE
KPFMNBKC_03510 2.5e-41 spoIIIAD S Stage III sporulation protein AD
KPFMNBKC_03511 7.6e-29 spoIIIAC S stage III sporulation protein AC
KPFMNBKC_03512 1.2e-83 spoIIIAB S Stage III sporulation protein
KPFMNBKC_03513 1.1e-172 spoIIIAA S stage III sporulation protein AA
KPFMNBKC_03514 1.8e-36 yqhV S Protein of unknown function (DUF2619)
KPFMNBKC_03515 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KPFMNBKC_03516 7.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KPFMNBKC_03517 3.7e-88 yqhR S Conserved membrane protein YqhR
KPFMNBKC_03518 2e-172 yqhQ S Protein of unknown function (DUF1385)
KPFMNBKC_03519 7.6e-62 yqhP
KPFMNBKC_03520 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
KPFMNBKC_03521 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KPFMNBKC_03522 3.7e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KPFMNBKC_03523 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
KPFMNBKC_03524 9.8e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KPFMNBKC_03525 3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KPFMNBKC_03526 1e-209 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KPFMNBKC_03527 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KPFMNBKC_03528 9.3e-152 yqhG S Bacterial protein YqhG of unknown function
KPFMNBKC_03529 3.4e-22 sinI S Anti-repressor SinI
KPFMNBKC_03530 7.8e-55 sinR K transcriptional
KPFMNBKC_03531 7.3e-141 tasA S Cell division protein FtsN
KPFMNBKC_03532 1.7e-70 sipW 3.4.21.89 U Signal peptidase
KPFMNBKC_03533 1.6e-120 yqxM
KPFMNBKC_03534 2.4e-53 yqzG S Protein of unknown function (DUF3889)
KPFMNBKC_03535 2.3e-26 yqzE S YqzE-like protein
KPFMNBKC_03536 8e-61 S ComG operon protein 7
KPFMNBKC_03537 1.7e-76 comGF U Putative Competence protein ComGF
KPFMNBKC_03538 2e-20 comGE
KPFMNBKC_03539 1.6e-73 gspH NU Tfp pilus assembly protein FimT
KPFMNBKC_03540 8.9e-50 comGC U Required for transformation and DNA binding
KPFMNBKC_03541 2.4e-184 comGB NU COG1459 Type II secretory pathway, component PulF
KPFMNBKC_03542 1.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KPFMNBKC_03543 1.2e-185 corA P Mg2 transporter protein
KPFMNBKC_03544 6.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KPFMNBKC_03545 1.6e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KPFMNBKC_03547 7.8e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
KPFMNBKC_03548 3.1e-37 yqgY S Protein of unknown function (DUF2626)
KPFMNBKC_03549 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KPFMNBKC_03550 1.2e-19 yqgW S Protein of unknown function (DUF2759)
KPFMNBKC_03551 6.9e-50 yqgV S Thiamine-binding protein
KPFMNBKC_03552 1.9e-197 yqgU
KPFMNBKC_03553 9.6e-219 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
KPFMNBKC_03554 2.6e-180 glcK 2.7.1.2 G Glucokinase
KPFMNBKC_03555 7e-210 nhaC C Na H antiporter
KPFMNBKC_03556 4e-07 yqgO
KPFMNBKC_03557 1.6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KPFMNBKC_03558 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KPFMNBKC_03559 1.2e-50 yqzD
KPFMNBKC_03560 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KPFMNBKC_03561 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPFMNBKC_03562 1.6e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPFMNBKC_03563 4.1e-156 pstA P Phosphate transport system permease
KPFMNBKC_03564 5.2e-154 pstC P probably responsible for the translocation of the substrate across the membrane
KPFMNBKC_03565 1.7e-157 pstS P Phosphate
KPFMNBKC_03566 0.0 pbpA 3.4.16.4 M penicillin-binding protein
KPFMNBKC_03567 2.6e-228 yqgE EGP Major facilitator superfamily
KPFMNBKC_03568 1.5e-114 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KPFMNBKC_03569 3e-76 yqgC S protein conserved in bacteria
KPFMNBKC_03570 5.7e-130 yqgB S Protein of unknown function (DUF1189)
KPFMNBKC_03571 1e-45 yqfZ M LysM domain
KPFMNBKC_03572 1.5e-200 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KPFMNBKC_03573 2.3e-52 yqfX S membrane
KPFMNBKC_03574 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KPFMNBKC_03575 2.9e-72 zur P Belongs to the Fur family
KPFMNBKC_03576 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KPFMNBKC_03577 9.3e-37 yqfT S Protein of unknown function (DUF2624)
KPFMNBKC_03578 1.7e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KPFMNBKC_03579 1.2e-247 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KPFMNBKC_03580 6.2e-51 yqfQ S YqfQ-like protein
KPFMNBKC_03581 3.8e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KPFMNBKC_03582 4.3e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KPFMNBKC_03583 2.2e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
KPFMNBKC_03584 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
KPFMNBKC_03585 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KPFMNBKC_03586 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KPFMNBKC_03587 1.8e-87 yaiI S Belongs to the UPF0178 family
KPFMNBKC_03588 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KPFMNBKC_03589 4.5e-112 ccpN K CBS domain
KPFMNBKC_03590 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KPFMNBKC_03591 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KPFMNBKC_03592 4.1e-144 recO L Involved in DNA repair and RecF pathway recombination
KPFMNBKC_03593 1.8e-16 S YqzL-like protein
KPFMNBKC_03594 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KPFMNBKC_03595 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KPFMNBKC_03596 1.7e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KPFMNBKC_03597 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KPFMNBKC_03598 0.0 yqfF S membrane-associated HD superfamily hydrolase
KPFMNBKC_03599 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
KPFMNBKC_03600 6.1e-216 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KPFMNBKC_03601 9.3e-46 yqfC S sporulation protein YqfC
KPFMNBKC_03602 9e-40 yqfB
KPFMNBKC_03603 5.8e-119 yqfA S UPF0365 protein
KPFMNBKC_03604 2e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
KPFMNBKC_03605 1.2e-68 yqeY S Yqey-like protein
KPFMNBKC_03606 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KPFMNBKC_03607 6.6e-157 yqeW P COG1283 Na phosphate symporter
KPFMNBKC_03608 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KPFMNBKC_03609 1.4e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KPFMNBKC_03610 2.3e-173 prmA J Methylates ribosomal protein L11
KPFMNBKC_03611 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KPFMNBKC_03612 0.0 dnaK O Heat shock 70 kDa protein
KPFMNBKC_03613 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KPFMNBKC_03614 2.3e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KPFMNBKC_03615 5.3e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
KPFMNBKC_03616 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KPFMNBKC_03617 3.8e-54 yqxA S Protein of unknown function (DUF3679)
KPFMNBKC_03618 4.1e-220 spoIIP M stage II sporulation protein P
KPFMNBKC_03619 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KPFMNBKC_03620 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
KPFMNBKC_03621 1.1e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
KPFMNBKC_03622 0.0 comEC S Competence protein ComEC
KPFMNBKC_03623 8e-105 comEB 3.5.4.12 F ComE operon protein 2
KPFMNBKC_03624 3.6e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KPFMNBKC_03625 2.7e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPFMNBKC_03626 9.3e-138 yqeM Q Methyltransferase
KPFMNBKC_03627 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KPFMNBKC_03628 2.1e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KPFMNBKC_03629 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KPFMNBKC_03630 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KPFMNBKC_03631 2.1e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KPFMNBKC_03632 3.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KPFMNBKC_03633 2e-94 yqeG S hydrolase of the HAD superfamily
KPFMNBKC_03635 5e-139 yqeF E GDSL-like Lipase/Acylhydrolase
KPFMNBKC_03636 4e-141 3.5.1.104 G Polysaccharide deacetylase
KPFMNBKC_03637 4.2e-107 yqeD S SNARE associated Golgi protein
KPFMNBKC_03638 1.3e-26 2.3.1.57 K Acetyltransferase (GNAT) domain
KPFMNBKC_03639 8.2e-219 EGP Major facilitator Superfamily
KPFMNBKC_03640 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KPFMNBKC_03641 2.2e-159 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
KPFMNBKC_03642 2e-89 K Transcriptional regulator PadR-like family
KPFMNBKC_03643 3e-69 psiE S Belongs to the PsiE family
KPFMNBKC_03644 4e-237 yrkQ T Histidine kinase
KPFMNBKC_03645 4.2e-124 T Transcriptional regulator
KPFMNBKC_03646 1.9e-220 yrkO P Protein of unknown function (DUF418)
KPFMNBKC_03648 3.8e-104 yrkN K Acetyltransferase (GNAT) family
KPFMNBKC_03649 1.5e-97 adk 2.7.4.3 F adenylate kinase activity
KPFMNBKC_03650 1e-31 yyaR K acetyltransferase
KPFMNBKC_03651 7.2e-71 tetL EGP Major facilitator Superfamily
KPFMNBKC_03652 3.7e-80 yyaR K Acetyltransferase (GNAT) domain
KPFMNBKC_03653 1.5e-91 yrdA S DinB family
KPFMNBKC_03655 2.9e-145 S hydrolase
KPFMNBKC_03656 7.8e-146 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
KPFMNBKC_03657 1.6e-129 glvR K Helix-turn-helix domain, rpiR family
KPFMNBKC_03658 7.9e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
KPFMNBKC_03659 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
KPFMNBKC_03660 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
KPFMNBKC_03661 4.1e-183 romA S Beta-lactamase superfamily domain
KPFMNBKC_03662 1.1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KPFMNBKC_03663 3.1e-164 yybE K Transcriptional regulator
KPFMNBKC_03664 1e-213 ynfM EGP Major facilitator Superfamily
KPFMNBKC_03665 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KPFMNBKC_03666 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
KPFMNBKC_03667 3.9e-93 yrhH Q methyltransferase
KPFMNBKC_03669 8e-143 focA P Formate nitrite
KPFMNBKC_03670 1.7e-60 yrhF S Uncharacterized conserved protein (DUF2294)
KPFMNBKC_03671 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KPFMNBKC_03672 2.2e-79 yrhD S Protein of unknown function (DUF1641)
KPFMNBKC_03673 1.8e-34 yrhC S YrhC-like protein
KPFMNBKC_03674 2.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KPFMNBKC_03675 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KPFMNBKC_03676 8e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPFMNBKC_03677 3.3e-115 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KPFMNBKC_03678 4.1e-27 yrzA S Protein of unknown function (DUF2536)
KPFMNBKC_03679 4e-287 yfiU EGP Major facilitator Superfamily
KPFMNBKC_03680 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
KPFMNBKC_03681 1.5e-45 yrdF K ribonuclease inhibitor
KPFMNBKC_03682 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
KPFMNBKC_03683 1.8e-177 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KPFMNBKC_03684 2.5e-112 1.6.5.2 S NADPH-dependent FMN reductase
KPFMNBKC_03685 8.6e-96 padR K transcriptional
KPFMNBKC_03686 7.2e-167 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KPFMNBKC_03687 8.6e-194 S Oxidoreductase
KPFMNBKC_03688 2.3e-157 G Xylose isomerase
KPFMNBKC_03689 1.2e-192 iolT EGP Major facilitator Superfamily
KPFMNBKC_03690 4.1e-98 K AraC-like ligand binding domain
KPFMNBKC_03691 2.6e-160 yfiE 1.13.11.2 S glyoxalase
KPFMNBKC_03692 7e-63 mhqP S DoxX
KPFMNBKC_03693 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KPFMNBKC_03694 1.7e-310 yfiB3 V ABC transporter
KPFMNBKC_03695 0.0 yobO M COG5434 Endopolygalacturonase
KPFMNBKC_03696 3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KPFMNBKC_03697 1.7e-139 glvR F Helix-turn-helix domain, rpiR family
KPFMNBKC_03698 7.6e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KPFMNBKC_03699 4.2e-15 sspH S Belongs to the SspH family
KPFMNBKC_03700 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KPFMNBKC_03701 1.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KPFMNBKC_03702 2.9e-213 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KPFMNBKC_03703 2.8e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KPFMNBKC_03704 1.1e-189 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KPFMNBKC_03705 6.8e-89 yfjM S Psort location Cytoplasmic, score
KPFMNBKC_03706 1.1e-191 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPFMNBKC_03707 1.2e-48 S YfzA-like protein
KPFMNBKC_03708 4.3e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPFMNBKC_03709 8.3e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KPFMNBKC_03710 8.5e-184 corA P Mediates influx of magnesium ions
KPFMNBKC_03711 1.4e-33
KPFMNBKC_03712 4e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KPFMNBKC_03713 9e-155 pdaA G deacetylase
KPFMNBKC_03714 4.9e-27 yfjT
KPFMNBKC_03715 5.6e-219 yfkA S YfkB-like domain
KPFMNBKC_03716 2.8e-146 yfkC M Mechanosensitive ion channel
KPFMNBKC_03717 1.2e-143 yfkD S YfkD-like protein
KPFMNBKC_03718 1.3e-185 cax P COG0387 Ca2 H antiporter
KPFMNBKC_03719 6.5e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
KPFMNBKC_03721 6.8e-145 yihY S Belongs to the UPF0761 family
KPFMNBKC_03722 3.5e-52 yfkI S gas vesicle protein
KPFMNBKC_03723 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KPFMNBKC_03724 2.7e-29 yfkK S Belongs to the UPF0435 family
KPFMNBKC_03725 5.6e-193 ydiM EGP Major facilitator Superfamily
KPFMNBKC_03726 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KPFMNBKC_03727 6.9e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KPFMNBKC_03728 3e-187 K helix_turn _helix lactose operon repressor
KPFMNBKC_03729 1e-90 yfkM 1.11.1.6, 3.5.1.124 S protease
KPFMNBKC_03730 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
KPFMNBKC_03731 2.7e-200 yibE S YibE/F-like protein
KPFMNBKC_03732 3.5e-124 yibF S YibE/F-like protein
KPFMNBKC_03733 5.8e-123 yfkO C nitroreductase
KPFMNBKC_03734 2.6e-129 treR K transcriptional
KPFMNBKC_03735 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KPFMNBKC_03736 4.3e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KPFMNBKC_03737 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
KPFMNBKC_03738 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
KPFMNBKC_03739 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
KPFMNBKC_03740 3.8e-63 yhdN S Domain of unknown function (DUF1992)
KPFMNBKC_03741 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KPFMNBKC_03742 3.7e-73 yfmQ S Uncharacterised protein from bacillus cereus group
KPFMNBKC_03743 8.7e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KPFMNBKC_03744 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
KPFMNBKC_03745 3.1e-50 yflH S Protein of unknown function (DUF3243)
KPFMNBKC_03746 1.6e-18 yflI
KPFMNBKC_03747 1.5e-14 yflJ S Protein of unknown function (DUF2639)
KPFMNBKC_03748 2.9e-122 yflK S protein conserved in bacteria
KPFMNBKC_03749 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KPFMNBKC_03750 9.3e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KPFMNBKC_03751 8.7e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KPFMNBKC_03752 2.5e-226 citM C Citrate transporter
KPFMNBKC_03753 1.6e-177 yflP S Tripartite tricarboxylate transporter family receptor
KPFMNBKC_03754 1.8e-119 citT T response regulator
KPFMNBKC_03755 1.8e-271 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KPFMNBKC_03756 6.8e-24 M1-820 Q Collagen triple helix repeat (20 copies)
KPFMNBKC_03757 5.6e-23 M1-820 Q Collagen triple helix repeat (20 copies)
KPFMNBKC_03759 1.8e-28 Q PFAM Collagen triple helix
KPFMNBKC_03760 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
KPFMNBKC_03761 7.7e-241 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
KPFMNBKC_03762 1.3e-57 yflT S Heat induced stress protein YflT
KPFMNBKC_03763 2e-24 S Protein of unknown function (DUF3212)
KPFMNBKC_03764 1.6e-188 yfmJ S N-terminal domain of oxidoreductase
KPFMNBKC_03765 1.5e-50 yfmK 2.3.1.128 K acetyltransferase
KPFMNBKC_03766 5.5e-206 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KPFMNBKC_03767 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KPFMNBKC_03768 8.9e-207 yfmO EGP Major facilitator Superfamily
KPFMNBKC_03769 9e-69 yfmP K transcriptional
KPFMNBKC_03770 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KPFMNBKC_03771 5.5e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KPFMNBKC_03772 1.5e-166 IQ Enoyl-(Acyl carrier protein) reductase
KPFMNBKC_03773 9.8e-115 yfmS NT chemotaxis protein
KPFMNBKC_03774 4.5e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KPFMNBKC_03775 3.3e-245 yfnA E amino acid
KPFMNBKC_03776 4.4e-217 fsr P COG0477 Permeases of the major facilitator superfamily
KPFMNBKC_03777 4e-186 yfnD M Nucleotide-diphospho-sugar transferase
KPFMNBKC_03778 3.9e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
KPFMNBKC_03779 4.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
KPFMNBKC_03780 3.5e-171 yfnG 4.2.1.45 M dehydratase
KPFMNBKC_03781 5.1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
KPFMNBKC_03782 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KPFMNBKC_03783 1.6e-146 2.1.1.163, 2.1.1.201 Q methyltransferase
KPFMNBKC_03784 1e-111 S CAAX protease self-immunity
KPFMNBKC_03785 9.5e-152 sagB C Nitroreductase family
KPFMNBKC_03786 5.8e-263 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
KPFMNBKC_03787 1.3e-190 S ATP diphosphatase activity
KPFMNBKC_03788 9.2e-127
KPFMNBKC_03789 7.1e-74 S protein homooligomerization
KPFMNBKC_03790 3.7e-126 V ABC-2 type transporter
KPFMNBKC_03791 4.1e-164 V ATPases associated with a variety of cellular activities
KPFMNBKC_03792 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
KPFMNBKC_03794 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KPFMNBKC_03795 8.3e-196 yetN S Protein of unknown function (DUF3900)
KPFMNBKC_03796 5.8e-208 yetM CH FAD binding domain
KPFMNBKC_03797 2.9e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
KPFMNBKC_03799 1.8e-105 yetJ S Belongs to the BI1 family
KPFMNBKC_03800 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
KPFMNBKC_03801 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
KPFMNBKC_03802 3.4e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KPFMNBKC_03803 5.8e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KPFMNBKC_03804 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KPFMNBKC_03805 8.7e-122 yetF S membrane
KPFMNBKC_03807 9.8e-97 yesJ K Acetyltransferase (GNAT) family
KPFMNBKC_03808 8.9e-104 cotJC P Spore Coat
KPFMNBKC_03809 3.3e-45 cotJB S CotJB protein
KPFMNBKC_03810 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
KPFMNBKC_03811 1.4e-108 aadK G Streptomycin adenylyltransferase
KPFMNBKC_03813 9.4e-127 yeeN K transcriptional regulatory protein
KPFMNBKC_03814 1.1e-248 yobL S Bacterial EndoU nuclease
KPFMNBKC_03815 9.9e-21 S Colicin immunity protein / pyocin immunity protein
KPFMNBKC_03816 3.8e-138 cylB V ABC-2 type transporter
KPFMNBKC_03817 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
KPFMNBKC_03818 8.1e-311 L Uncharacterized conserved protein (DUF2075)
KPFMNBKC_03819 1.6e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPFMNBKC_03820 1.9e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KPFMNBKC_03821 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KPFMNBKC_03822 4e-153 yerO K Transcriptional regulator
KPFMNBKC_03823 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPFMNBKC_03824 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KPFMNBKC_03825 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPFMNBKC_03826 3.7e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KPFMNBKC_03827 1.5e-121 sapB S MgtC SapB transporter

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)