ORF_ID e_value Gene_name EC_number CAZy COGs Description
MEPHMAFF_00001 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEPHMAFF_00002 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEPHMAFF_00003 1.6e-81 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
MEPHMAFF_00004 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
MEPHMAFF_00005 1.7e-34 yaaA S S4 domain protein YaaA
MEPHMAFF_00006 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEPHMAFF_00007 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEPHMAFF_00008 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEPHMAFF_00009 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MEPHMAFF_00010 1.4e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MEPHMAFF_00011 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEPHMAFF_00012 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MEPHMAFF_00013 2e-74 rplI J Binds to the 23S rRNA
MEPHMAFF_00014 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MEPHMAFF_00015 9.9e-206 yttB EGP Major facilitator Superfamily
MEPHMAFF_00016 3.7e-54
MEPHMAFF_00017 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
MEPHMAFF_00018 9.8e-09 K DNA-binding helix-turn-helix protein
MEPHMAFF_00019 1.4e-125 O Bacterial dnaA protein
MEPHMAFF_00020 1.6e-214 L Integrase core domain
MEPHMAFF_00022 1.1e-18 K helix_turn_helix multiple antibiotic resistance protein
MEPHMAFF_00023 1.2e-190 L PFAM Integrase catalytic region
MEPHMAFF_00024 1.6e-32 K helix_turn_helix multiple antibiotic resistance protein
MEPHMAFF_00025 1.3e-293 lmrA 3.6.3.44 V ABC transporter
MEPHMAFF_00027 6.8e-130 K response regulator
MEPHMAFF_00028 0.0 vicK 2.7.13.3 T Histidine kinase
MEPHMAFF_00029 2.1e-246 yycH S YycH protein
MEPHMAFF_00030 2.7e-149 yycI S YycH protein
MEPHMAFF_00031 3.8e-153 vicX 3.1.26.11 S domain protein
MEPHMAFF_00032 2.1e-214 htrA 3.4.21.107 O serine protease
MEPHMAFF_00033 1e-87 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
MEPHMAFF_00034 4.7e-177 ABC-SBP S ABC transporter
MEPHMAFF_00035 1e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEPHMAFF_00037 2.9e-96 S reductase
MEPHMAFF_00038 1.9e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
MEPHMAFF_00039 3e-147 E Glyoxalase-like domain
MEPHMAFF_00040 8.6e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEPHMAFF_00041 2.3e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MEPHMAFF_00042 5.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MEPHMAFF_00043 4.4e-129 V ABC transporter
MEPHMAFF_00044 2.5e-212 bacI V MacB-like periplasmic core domain
MEPHMAFF_00045 3.5e-35
MEPHMAFF_00046 6.2e-190 L PFAM Integrase catalytic region
MEPHMAFF_00047 1.3e-260 S Putative peptidoglycan binding domain
MEPHMAFF_00049 2.3e-14 2.7.13.3 T GHKL domain
MEPHMAFF_00050 4.7e-55 2.7.13.3 T GHKL domain
MEPHMAFF_00051 6.3e-187 L PFAM Integrase catalytic region
MEPHMAFF_00052 9.1e-68 osmC O OsmC-like protein
MEPHMAFF_00053 2e-169 L Transposase and inactivated derivatives IS30 family
MEPHMAFF_00054 7.8e-32
MEPHMAFF_00055 0.0 clpL O associated with various cellular activities
MEPHMAFF_00057 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
MEPHMAFF_00058 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEPHMAFF_00059 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MEPHMAFF_00060 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MEPHMAFF_00061 1.5e-172 malR K Transcriptional regulator, LacI family
MEPHMAFF_00062 6.3e-213 phbA 2.3.1.9 I Belongs to the thiolase family
MEPHMAFF_00063 3.6e-260 S Uncharacterised protein family (UPF0236)
MEPHMAFF_00064 1.1e-256 malT G Major Facilitator
MEPHMAFF_00065 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MEPHMAFF_00066 2.1e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MEPHMAFF_00067 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
MEPHMAFF_00068 2.9e-79 K response regulator
MEPHMAFF_00069 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_00070 5.3e-226 sptS 2.7.13.3 T Histidine kinase
MEPHMAFF_00071 2.5e-209 yfeO P Voltage gated chloride channel
MEPHMAFF_00072 1.8e-101 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MEPHMAFF_00073 6.6e-136 puuD S peptidase C26
MEPHMAFF_00074 3.8e-167 yvgN C Aldo keto reductase
MEPHMAFF_00075 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
MEPHMAFF_00076 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
MEPHMAFF_00077 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
MEPHMAFF_00078 4.2e-261 nox C NADH oxidase
MEPHMAFF_00079 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEPHMAFF_00080 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEPHMAFF_00081 3e-86
MEPHMAFF_00082 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MEPHMAFF_00084 4.3e-13 K Transcriptional regulator, TetR family
MEPHMAFF_00085 3.1e-75 K Transcriptional regulator, TetR family
MEPHMAFF_00086 1.4e-71
MEPHMAFF_00087 9e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
MEPHMAFF_00088 1.6e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
MEPHMAFF_00089 4.9e-278 M domain protein
MEPHMAFF_00090 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MEPHMAFF_00091 4.9e-265 G Major Facilitator
MEPHMAFF_00092 1.3e-235 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MEPHMAFF_00093 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MEPHMAFF_00094 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MEPHMAFF_00095 1.6e-260 G Major Facilitator
MEPHMAFF_00096 1.7e-182 K Transcriptional regulator, LacI family
MEPHMAFF_00097 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEPHMAFF_00099 1.2e-100 nqr 1.5.1.36 S reductase
MEPHMAFF_00100 6.1e-198 XK27_09615 S reductase
MEPHMAFF_00101 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEPHMAFF_00102 8.1e-238 L Transposase
MEPHMAFF_00103 8.1e-238 L Transposase
MEPHMAFF_00104 1.2e-190 L PFAM Integrase catalytic region
MEPHMAFF_00105 3.9e-27 mleP3 S Membrane transport protein
MEPHMAFF_00106 7.3e-121 T Transcriptional regulatory protein, C terminal
MEPHMAFF_00107 4.9e-238 T GHKL domain
MEPHMAFF_00108 4.7e-109 S Peptidase propeptide and YPEB domain
MEPHMAFF_00109 6.4e-21 P nitric oxide dioxygenase activity
MEPHMAFF_00110 1.3e-17 P FAD-binding domain
MEPHMAFF_00111 4.3e-55 yphJ 4.1.1.44 S decarboxylase
MEPHMAFF_00112 5.3e-83 K Bacterial regulatory proteins, tetR family
MEPHMAFF_00113 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MEPHMAFF_00114 8.2e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
MEPHMAFF_00115 7.3e-166 S Oxidoreductase, aldo keto reductase family protein
MEPHMAFF_00116 2.7e-85 C Flavodoxin
MEPHMAFF_00117 5.6e-158 K Transcriptional regulator
MEPHMAFF_00118 9.2e-15 lacA S transferase hexapeptide repeat
MEPHMAFF_00119 3.6e-58 lacA S transferase hexapeptide repeat
MEPHMAFF_00120 9.4e-32 S thiolester hydrolase activity
MEPHMAFF_00121 2.2e-151 S Alpha beta hydrolase
MEPHMAFF_00122 2.3e-93 padC Q Phenolic acid decarboxylase
MEPHMAFF_00123 3.3e-92 padR K Virulence activator alpha C-term
MEPHMAFF_00124 1.4e-65 GM NAD(P)H-binding
MEPHMAFF_00125 2.3e-155 ypuA S Protein of unknown function (DUF1002)
MEPHMAFF_00126 1.2e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
MEPHMAFF_00127 4.3e-59 K Transcriptional regulator
MEPHMAFF_00128 4.3e-40 K Transcriptional regulator
MEPHMAFF_00129 7.6e-163 akr5f 1.1.1.346 S reductase
MEPHMAFF_00130 1.8e-104 K Transcriptional regulator C-terminal region
MEPHMAFF_00131 2.1e-74 S membrane
MEPHMAFF_00132 6.1e-88 S membrane
MEPHMAFF_00133 1.2e-112 GM NAD(P)H-binding
MEPHMAFF_00134 1.1e-64 yneR
MEPHMAFF_00135 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
MEPHMAFF_00136 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_00137 2.2e-20 L PFAM Integrase catalytic region
MEPHMAFF_00138 8.1e-238 L Transposase
MEPHMAFF_00139 9.8e-92 L PFAM Integrase catalytic region
MEPHMAFF_00140 1.5e-121 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
MEPHMAFF_00141 6.6e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MEPHMAFF_00142 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
MEPHMAFF_00143 2e-169 L Transposase and inactivated derivatives IS30 family
MEPHMAFF_00144 2e-92 folT S ECF transporter, substrate-specific component
MEPHMAFF_00145 0.0 pepN 3.4.11.2 E aminopeptidase
MEPHMAFF_00146 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
MEPHMAFF_00147 2.8e-254 pepC 3.4.22.40 E aminopeptidase
MEPHMAFF_00148 1.4e-209 EGP Major facilitator Superfamily
MEPHMAFF_00149 2e-169 L Transposase and inactivated derivatives IS30 family
MEPHMAFF_00150 1.8e-229
MEPHMAFF_00151 3.5e-79 K Transcriptional regulator, HxlR family
MEPHMAFF_00152 3.7e-108 XK27_02070 S Nitroreductase family
MEPHMAFF_00153 3.5e-49 hxlR K Transcriptional regulator, HxlR family
MEPHMAFF_00154 3e-119 GM NmrA-like family
MEPHMAFF_00155 6.4e-70 elaA S Gnat family
MEPHMAFF_00156 1.8e-39 S Cytochrome B5
MEPHMAFF_00157 5.4e-09 S Cytochrome B5
MEPHMAFF_00158 7.8e-41 S Cytochrome B5
MEPHMAFF_00159 6.7e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
MEPHMAFF_00161 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEPHMAFF_00162 1.1e-240 E amino acid
MEPHMAFF_00163 2.8e-215 npp S type I phosphodiesterase nucleotide pyrophosphatase
MEPHMAFF_00164 3.1e-226 yxiO S Vacuole effluxer Atg22 like
MEPHMAFF_00166 4.4e-100 L Helix-turn-helix domain
MEPHMAFF_00167 4.5e-160 L hmm pf00665
MEPHMAFF_00168 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEPHMAFF_00169 3e-34
MEPHMAFF_00170 1.1e-264 L PFAM Integrase catalytic region
MEPHMAFF_00171 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
MEPHMAFF_00172 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
MEPHMAFF_00173 2.6e-86 ygfC K transcriptional regulator (TetR family)
MEPHMAFF_00174 1.8e-182 hrtB V ABC transporter permease
MEPHMAFF_00175 1.8e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MEPHMAFF_00176 0.0 yhcA V ABC transporter, ATP-binding protein
MEPHMAFF_00177 4.6e-38
MEPHMAFF_00178 3.5e-49 czrA K Transcriptional regulator, ArsR family
MEPHMAFF_00179 2.2e-211 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEPHMAFF_00180 5.1e-173 scrR K Transcriptional regulator, LacI family
MEPHMAFF_00181 3e-24
MEPHMAFF_00182 8.2e-103
MEPHMAFF_00183 2.6e-214 yttB EGP Major facilitator Superfamily
MEPHMAFF_00184 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MEPHMAFF_00185 2.2e-87
MEPHMAFF_00186 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MEPHMAFF_00187 7.3e-261 S Putative peptidoglycan binding domain
MEPHMAFF_00188 1.2e-260 S Uncharacterised protein family (UPF0236)
MEPHMAFF_00189 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_00190 1.4e-124 yciB M ErfK YbiS YcfS YnhG
MEPHMAFF_00192 7.2e-101
MEPHMAFF_00193 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MEPHMAFF_00194 5.5e-126 S Alpha beta hydrolase
MEPHMAFF_00195 1.7e-207 gldA 1.1.1.6 C dehydrogenase
MEPHMAFF_00196 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEPHMAFF_00197 1.3e-41
MEPHMAFF_00198 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
MEPHMAFF_00199 1.1e-27 S C4-dicarboxylate anaerobic carrier
MEPHMAFF_00200 1.8e-240 S C4-dicarboxylate anaerobic carrier
MEPHMAFF_00201 1.8e-251 nhaC C Na H antiporter NhaC
MEPHMAFF_00202 1.6e-241 pbuX F xanthine permease
MEPHMAFF_00203 1.4e-283 pipD E Dipeptidase
MEPHMAFF_00204 3.9e-304 L Transposase
MEPHMAFF_00205 2.2e-168 corA P CorA-like Mg2+ transporter protein
MEPHMAFF_00206 4.5e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MEPHMAFF_00207 2.3e-131 terC P membrane
MEPHMAFF_00208 2.1e-54 trxA O Belongs to the thioredoxin family
MEPHMAFF_00209 1.6e-236 mepA V MATE efflux family protein
MEPHMAFF_00210 3.2e-55 M Leucine-rich repeat (LRR) protein
MEPHMAFF_00211 6.8e-56 K Transcriptional regulator, ArsR family
MEPHMAFF_00212 5e-91 P Cadmium resistance transporter
MEPHMAFF_00213 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
MEPHMAFF_00214 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MEPHMAFF_00215 2.2e-182 ABC-SBP S ABC transporter
MEPHMAFF_00216 1e-73 M PFAM NLP P60 protein
MEPHMAFF_00218 1.2e-190 L PFAM Integrase catalytic region
MEPHMAFF_00219 8.2e-48
MEPHMAFF_00220 7.8e-272 S ABC transporter, ATP-binding protein
MEPHMAFF_00221 2.3e-142 S Putative ABC-transporter type IV
MEPHMAFF_00222 2e-106 NU mannosyl-glycoprotein
MEPHMAFF_00223 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
MEPHMAFF_00224 1.5e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
MEPHMAFF_00225 7.6e-205 nrnB S DHHA1 domain
MEPHMAFF_00227 6.9e-49
MEPHMAFF_00228 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MEPHMAFF_00229 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MEPHMAFF_00230 2e-15 S Domain of unknown function (DUF4767)
MEPHMAFF_00231 9.5e-55
MEPHMAFF_00232 8.4e-117 yrkL S Flavodoxin-like fold
MEPHMAFF_00234 1.6e-64 yeaO S Protein of unknown function, DUF488
MEPHMAFF_00235 7.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MEPHMAFF_00236 3e-204 3.1.3.1 S associated with various cellular activities
MEPHMAFF_00237 3.5e-241 S Putative metallopeptidase domain
MEPHMAFF_00238 5.1e-47
MEPHMAFF_00239 0.0 pepO 3.4.24.71 O Peptidase family M13
MEPHMAFF_00240 8.4e-111 K Helix-turn-helix domain
MEPHMAFF_00241 3.5e-88 ymdB S Macro domain protein
MEPHMAFF_00242 8.1e-238 L Transposase
MEPHMAFF_00243 1.6e-197 EGP Major facilitator Superfamily
MEPHMAFF_00244 2.7e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEPHMAFF_00245 6.1e-54 K helix_turn_helix, mercury resistance
MEPHMAFF_00246 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MEPHMAFF_00247 4.1e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MEPHMAFF_00248 0.0 ysaB V FtsX-like permease family
MEPHMAFF_00249 2.6e-135 macB2 V ABC transporter, ATP-binding protein
MEPHMAFF_00250 1.3e-179 T PhoQ Sensor
MEPHMAFF_00251 1.2e-123 K response regulator
MEPHMAFF_00252 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
MEPHMAFF_00253 8.9e-136 pnuC H nicotinamide mononucleotide transporter
MEPHMAFF_00254 2.2e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEPHMAFF_00255 2.3e-204
MEPHMAFF_00256 2.6e-52
MEPHMAFF_00257 9.1e-36
MEPHMAFF_00258 4.8e-93 yxkA S Phosphatidylethanolamine-binding protein
MEPHMAFF_00259 4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
MEPHMAFF_00260 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
MEPHMAFF_00261 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MEPHMAFF_00262 2.2e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MEPHMAFF_00263 2e-180 galR K Transcriptional regulator
MEPHMAFF_00264 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_00265 8.4e-100 dedA 3.1.3.1 S SNARE associated Golgi protein
MEPHMAFF_00266 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEPHMAFF_00267 1.5e-80 K AsnC family
MEPHMAFF_00268 1.5e-80 uspA T universal stress protein
MEPHMAFF_00269 1.9e-41 ltrA S Bacterial low temperature requirement A protein (LtrA)
MEPHMAFF_00270 0.0 lacS G Transporter
MEPHMAFF_00271 1.8e-38
MEPHMAFF_00272 5.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEPHMAFF_00273 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MEPHMAFF_00274 3.1e-193 yeaN P Transporter, major facilitator family protein
MEPHMAFF_00275 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
MEPHMAFF_00276 9.9e-85 nrdI F Belongs to the NrdI family
MEPHMAFF_00277 6.2e-241 yhdP S Transporter associated domain
MEPHMAFF_00278 1.7e-154 ypdB V (ABC) transporter
MEPHMAFF_00279 4.8e-88 GM epimerase
MEPHMAFF_00280 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
MEPHMAFF_00281 1.1e-77 yybA 2.3.1.57 K Transcriptional regulator
MEPHMAFF_00282 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
MEPHMAFF_00283 2.8e-170 S AI-2E family transporter
MEPHMAFF_00284 2.9e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
MEPHMAFF_00285 1.9e-161
MEPHMAFF_00286 2.6e-185 L PFAM Integrase catalytic region
MEPHMAFF_00287 6e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MEPHMAFF_00288 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEPHMAFF_00289 2.9e-310 lmrA V ABC transporter, ATP-binding protein
MEPHMAFF_00290 0.0 yfiC V ABC transporter
MEPHMAFF_00291 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_00292 1.1e-283 pipD E Dipeptidase
MEPHMAFF_00293 1.3e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MEPHMAFF_00294 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
MEPHMAFF_00295 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MEPHMAFF_00296 4e-237 L Transposase
MEPHMAFF_00297 1.8e-243 yagE E amino acid
MEPHMAFF_00298 1.7e-139 aroD S Serine hydrolase (FSH1)
MEPHMAFF_00299 5.3e-240 brnQ U Component of the transport system for branched-chain amino acids
MEPHMAFF_00300 5.2e-167 GK ROK family
MEPHMAFF_00301 0.0 tetP J elongation factor G
MEPHMAFF_00302 5.1e-81 uspA T universal stress protein
MEPHMAFF_00303 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
MEPHMAFF_00304 7.1e-63
MEPHMAFF_00305 5.2e-14
MEPHMAFF_00306 4.1e-212 EGP Major facilitator Superfamily
MEPHMAFF_00307 1.3e-257 G PTS system Galactitol-specific IIC component
MEPHMAFF_00308 2.6e-180 1.6.5.5 C Zinc-binding dehydrogenase
MEPHMAFF_00309 3.1e-161
MEPHMAFF_00310 1e-72 K Transcriptional regulator
MEPHMAFF_00311 1.8e-189 D Alpha beta
MEPHMAFF_00312 2.2e-52 ypaA S Protein of unknown function (DUF1304)
MEPHMAFF_00313 0.0 yjcE P Sodium proton antiporter
MEPHMAFF_00314 1.6e-52 yvlA
MEPHMAFF_00315 1.8e-113 P Cobalt transport protein
MEPHMAFF_00316 1e-246 cbiO1 S ABC transporter, ATP-binding protein
MEPHMAFF_00317 3e-96 S ABC-type cobalt transport system, permease component
MEPHMAFF_00318 3.3e-133 S membrane transporter protein
MEPHMAFF_00319 2.5e-138 IQ KR domain
MEPHMAFF_00320 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
MEPHMAFF_00321 1.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
MEPHMAFF_00322 6.7e-150 L hmm pf00665
MEPHMAFF_00323 2.5e-127 L Helix-turn-helix domain
MEPHMAFF_00324 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MEPHMAFF_00325 1.8e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
MEPHMAFF_00326 2.8e-255 yagE E amino acid
MEPHMAFF_00327 3.4e-85 dps P Belongs to the Dps family
MEPHMAFF_00328 0.0 pacL 3.6.3.8 P P-type ATPase
MEPHMAFF_00329 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MEPHMAFF_00330 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MEPHMAFF_00331 1e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MEPHMAFF_00332 4.5e-146 potB P ABC transporter permease
MEPHMAFF_00333 4.9e-140 potC P ABC transporter permease
MEPHMAFF_00334 4.3e-208 potD P ABC transporter
MEPHMAFF_00335 5.3e-229
MEPHMAFF_00336 7.2e-234 EGP Sugar (and other) transporter
MEPHMAFF_00337 3e-254 yfnA E Amino Acid
MEPHMAFF_00338 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MEPHMAFF_00339 1.9e-101 gmk2 2.7.4.8 F Guanylate kinase
MEPHMAFF_00340 1.5e-82 zur P Belongs to the Fur family
MEPHMAFF_00341 4e-17 3.2.1.14 GH18
MEPHMAFF_00342 7.1e-150
MEPHMAFF_00343 5.8e-39 pspC KT PspC domain protein
MEPHMAFF_00344 1.6e-94 K Transcriptional regulator (TetR family)
MEPHMAFF_00345 4.8e-222 V domain protein
MEPHMAFF_00346 2.9e-182 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEPHMAFF_00348 6.6e-35 S Transglycosylase associated protein
MEPHMAFF_00349 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEPHMAFF_00350 2.7e-125 3.1.3.73 G phosphoglycerate mutase
MEPHMAFF_00351 2.6e-115 dedA S SNARE associated Golgi protein
MEPHMAFF_00352 0.0 helD 3.6.4.12 L DNA helicase
MEPHMAFF_00353 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
MEPHMAFF_00354 4.7e-157 EG EamA-like transporter family
MEPHMAFF_00355 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEPHMAFF_00356 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
MEPHMAFF_00357 1.5e-225 S cog cog1373
MEPHMAFF_00359 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MEPHMAFF_00360 2.4e-264 L PFAM Integrase catalytic region
MEPHMAFF_00361 4.9e-224 oxlT P Major Facilitator Superfamily
MEPHMAFF_00362 1.1e-158 spoU 2.1.1.185 J Methyltransferase
MEPHMAFF_00363 2.9e-130 L PFAM Integrase catalytic region
MEPHMAFF_00364 9.5e-112 S Membrane
MEPHMAFF_00365 1.2e-64 O Zinc-dependent metalloprotease
MEPHMAFF_00366 4.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MEPHMAFF_00367 1.6e-157 metQ_4 P Belongs to the nlpA lipoprotein family
MEPHMAFF_00369 1.5e-17 NU Mycoplasma protein of unknown function, DUF285
MEPHMAFF_00370 2.8e-93 L PFAM Integrase catalytic region
MEPHMAFF_00371 1.1e-59 L PFAM Integrase catalytic region
MEPHMAFF_00372 1.7e-183 S Phosphotransferase system, EIIC
MEPHMAFF_00373 2.4e-264 L PFAM Integrase catalytic region
MEPHMAFF_00374 2.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEPHMAFF_00375 1.2e-190 L PFAM Integrase catalytic region
MEPHMAFF_00376 3.9e-133 K Transcriptional regulatory protein, C-terminal domain protein
MEPHMAFF_00377 8.6e-159 pstS P Phosphate
MEPHMAFF_00378 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
MEPHMAFF_00379 2.1e-152 pstA P Phosphate transport system permease protein PstA
MEPHMAFF_00380 8.9e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEPHMAFF_00381 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
MEPHMAFF_00382 3e-09
MEPHMAFF_00383 5.7e-112
MEPHMAFF_00384 1.6e-157 ydaM M Glycosyl transferase family group 2
MEPHMAFF_00385 1.4e-217 G Glycosyl hydrolases family 8
MEPHMAFF_00386 3.9e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MEPHMAFF_00387 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
MEPHMAFF_00388 1.7e-238 ktrB P Potassium uptake protein
MEPHMAFF_00389 1.4e-116 ktrA P domain protein
MEPHMAFF_00390 1.2e-81 Q Methyltransferase
MEPHMAFF_00391 1.1e-231 mntH P H( )-stimulated, divalent metal cation uptake system
MEPHMAFF_00392 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MEPHMAFF_00393 1.6e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MEPHMAFF_00394 9.3e-95 S NADPH-dependent FMN reductase
MEPHMAFF_00395 1e-232 G Belongs to the glycosyl hydrolase family 6
MEPHMAFF_00396 4.7e-180 MA20_14895 S Conserved hypothetical protein 698
MEPHMAFF_00397 7.2e-135 I alpha/beta hydrolase fold
MEPHMAFF_00398 4.1e-169 lsa S ABC transporter
MEPHMAFF_00399 1.2e-260 S Uncharacterised protein family (UPF0236)
MEPHMAFF_00400 2.2e-274 arcD S C4-dicarboxylate anaerobic carrier
MEPHMAFF_00401 2.6e-255 ytjP 3.5.1.18 E Dipeptidase
MEPHMAFF_00402 5.3e-215 uhpT EGP Major facilitator Superfamily
MEPHMAFF_00403 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
MEPHMAFF_00404 4.8e-132 ponA V Beta-lactamase enzyme family
MEPHMAFF_00405 2.2e-116 L PFAM Integrase catalytic region
MEPHMAFF_00406 1.1e-64 L PFAM Integrase catalytic region
MEPHMAFF_00407 7.4e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MEPHMAFF_00408 3e-75
MEPHMAFF_00409 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MEPHMAFF_00410 1.9e-25
MEPHMAFF_00411 7.1e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
MEPHMAFF_00412 7.2e-169 L transposase, IS605 OrfB family
MEPHMAFF_00413 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
MEPHMAFF_00414 1.1e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
MEPHMAFF_00415 1.8e-107 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEPHMAFF_00416 2e-169 L Transposase and inactivated derivatives IS30 family
MEPHMAFF_00417 1.9e-161 mleR K LysR family
MEPHMAFF_00418 1.8e-303 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MEPHMAFF_00419 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MEPHMAFF_00420 1.8e-267 frdC 1.3.5.4 C FAD binding domain
MEPHMAFF_00421 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
MEPHMAFF_00422 1e-159 mleR K LysR family
MEPHMAFF_00423 2e-250 yjjP S Putative threonine/serine exporter
MEPHMAFF_00424 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
MEPHMAFF_00425 2.5e-281 emrY EGP Major facilitator Superfamily
MEPHMAFF_00426 3.4e-188 I Alpha beta
MEPHMAFF_00427 4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MEPHMAFF_00428 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEPHMAFF_00430 4.6e-160 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MEPHMAFF_00431 9.5e-119 S Domain of unknown function (DUF4811)
MEPHMAFF_00432 2.7e-269 lmrB EGP Major facilitator Superfamily
MEPHMAFF_00433 4.9e-73 merR K MerR HTH family regulatory protein
MEPHMAFF_00434 2.5e-53
MEPHMAFF_00435 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEPHMAFF_00436 1.1e-217 S CAAX protease self-immunity
MEPHMAFF_00437 1.4e-108 glnP P ABC transporter permease
MEPHMAFF_00438 4.2e-110 gluC P ABC transporter permease
MEPHMAFF_00439 7.5e-152 glnH ET ABC transporter
MEPHMAFF_00440 6.9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEPHMAFF_00441 5.5e-83 usp1 T Belongs to the universal stress protein A family
MEPHMAFF_00442 1.3e-109 S VIT family
MEPHMAFF_00443 1.4e-116 S membrane
MEPHMAFF_00444 2.6e-166 czcD P cation diffusion facilitator family transporter
MEPHMAFF_00445 1.1e-124 sirR K iron dependent repressor
MEPHMAFF_00446 3.5e-31 cspC K Cold shock protein
MEPHMAFF_00447 3.6e-129 thrE S Putative threonine/serine exporter
MEPHMAFF_00448 6.7e-81 S Threonine/Serine exporter, ThrE
MEPHMAFF_00449 2.7e-120 lssY 3.6.1.27 I phosphatase
MEPHMAFF_00450 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
MEPHMAFF_00451 3.8e-276 lysP E amino acid
MEPHMAFF_00452 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MEPHMAFF_00458 5.3e-130 S Hydrolases of the alpha beta superfamily
MEPHMAFF_00459 1.3e-16 S Hydrolases of the alpha beta superfamily
MEPHMAFF_00460 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
MEPHMAFF_00461 3.4e-77 ctsR K Belongs to the CtsR family
MEPHMAFF_00462 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEPHMAFF_00463 1e-110 K Bacterial regulatory proteins, tetR family
MEPHMAFF_00464 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEPHMAFF_00465 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEPHMAFF_00466 2.2e-202 ykiI
MEPHMAFF_00467 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MEPHMAFF_00468 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEPHMAFF_00469 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEPHMAFF_00470 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEPHMAFF_00471 8.9e-237 L Transposase
MEPHMAFF_00472 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MEPHMAFF_00473 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEPHMAFF_00474 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
MEPHMAFF_00475 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEPHMAFF_00476 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEPHMAFF_00477 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEPHMAFF_00478 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEPHMAFF_00479 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEPHMAFF_00480 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEPHMAFF_00481 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
MEPHMAFF_00482 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEPHMAFF_00483 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEPHMAFF_00484 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEPHMAFF_00485 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEPHMAFF_00486 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEPHMAFF_00487 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEPHMAFF_00488 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEPHMAFF_00489 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEPHMAFF_00490 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEPHMAFF_00491 2.9e-24 rpmD J Ribosomal protein L30
MEPHMAFF_00492 8.9e-64 rplO J Binds to the 23S rRNA
MEPHMAFF_00493 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEPHMAFF_00494 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEPHMAFF_00495 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEPHMAFF_00496 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MEPHMAFF_00497 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEPHMAFF_00498 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEPHMAFF_00499 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEPHMAFF_00500 1.1e-62 rplQ J Ribosomal protein L17
MEPHMAFF_00501 8.8e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEPHMAFF_00502 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEPHMAFF_00503 5.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEPHMAFF_00504 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEPHMAFF_00505 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEPHMAFF_00506 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MEPHMAFF_00507 2.1e-216 L Transposase
MEPHMAFF_00508 1.2e-190 L PFAM Integrase catalytic region
MEPHMAFF_00509 3.6e-140 IQ reductase
MEPHMAFF_00510 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
MEPHMAFF_00511 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MEPHMAFF_00512 3.3e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MEPHMAFF_00513 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MEPHMAFF_00514 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEPHMAFF_00515 2.1e-202 camS S sex pheromone
MEPHMAFF_00516 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEPHMAFF_00517 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MEPHMAFF_00518 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEPHMAFF_00519 5.1e-187 yegS 2.7.1.107 G Lipid kinase
MEPHMAFF_00520 1e-262 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEPHMAFF_00521 9.5e-47 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
MEPHMAFF_00522 0.0 L Helicase C-terminal domain protein
MEPHMAFF_00523 1.4e-20
MEPHMAFF_00524 4.5e-185 L PFAM Integrase catalytic region
MEPHMAFF_00525 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MEPHMAFF_00526 7.9e-35 copZ C Heavy-metal-associated domain
MEPHMAFF_00527 6.7e-93 dps P Belongs to the Dps family
MEPHMAFF_00528 5.8e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MEPHMAFF_00529 1.4e-38 L PFAM Integrase catalytic region
MEPHMAFF_00530 9.8e-53 L PFAM Integrase catalytic region
MEPHMAFF_00531 2.7e-26 K TRANSCRIPTIONal
MEPHMAFF_00533 7.9e-61 pldB 3.1.1.5 I Serine aminopeptidase, S33
MEPHMAFF_00534 5.6e-79 pncA Q Isochorismatase family
MEPHMAFF_00535 4e-230 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEPHMAFF_00536 4.2e-111 3.6.1.13, 3.6.1.55 F NUDIX domain
MEPHMAFF_00537 2.8e-71 L PFAM Integrase catalytic region
MEPHMAFF_00538 9.9e-67 L PFAM Integrase catalytic region
MEPHMAFF_00539 3.2e-96 S PFAM Archaeal ATPase
MEPHMAFF_00540 1.3e-46
MEPHMAFF_00542 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MEPHMAFF_00543 7.9e-158 amtB P ammonium transporter
MEPHMAFF_00544 2.1e-249 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
MEPHMAFF_00545 1.8e-90 S B3 4 domain
MEPHMAFF_00546 2.1e-91
MEPHMAFF_00547 4.8e-122 pnb C nitroreductase
MEPHMAFF_00548 2e-74 ogt 2.1.1.63 L Methyltransferase
MEPHMAFF_00549 5.8e-54 XK27_00915 C Luciferase-like monooxygenase
MEPHMAFF_00550 6.7e-106 XK27_00915 C Luciferase-like monooxygenase
MEPHMAFF_00551 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_00552 2.6e-151 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
MEPHMAFF_00553 7.3e-69 S Protein of unknown function (DUF3021)
MEPHMAFF_00554 9.3e-69 L Helix-turn-helix domain
MEPHMAFF_00555 9e-137 L hmm pf00665
MEPHMAFF_00556 6.9e-50 K LytTr DNA-binding domain
MEPHMAFF_00557 9.1e-92 K Acetyltransferase (GNAT) family
MEPHMAFF_00558 3.1e-21
MEPHMAFF_00559 7.6e-121 ybhL S Belongs to the BI1 family
MEPHMAFF_00560 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
MEPHMAFF_00561 9.3e-197 S Protein of unknown function (DUF3114)
MEPHMAFF_00562 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MEPHMAFF_00563 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MEPHMAFF_00564 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
MEPHMAFF_00565 9.1e-62 S Domain of unknown function (DUF4828)
MEPHMAFF_00566 4.5e-191 mocA S Oxidoreductase
MEPHMAFF_00567 7.7e-228 yfmL L DEAD DEAH box helicase
MEPHMAFF_00569 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MEPHMAFF_00570 9.3e-56
MEPHMAFF_00571 2.3e-67 gtcA S Teichoic acid glycosylation protein
MEPHMAFF_00572 6.1e-79 fld C Flavodoxin
MEPHMAFF_00573 1.1e-166 map 3.4.11.18 E Methionine Aminopeptidase
MEPHMAFF_00574 1.7e-220 arcT 2.6.1.1 E Aminotransferase
MEPHMAFF_00575 1.2e-194 E Arginine ornithine antiporter
MEPHMAFF_00576 1.4e-44 E Arginine ornithine antiporter
MEPHMAFF_00577 4.1e-281 yjeM E Amino Acid
MEPHMAFF_00578 3.2e-153 yihY S Belongs to the UPF0761 family
MEPHMAFF_00579 6.6e-34 S Protein of unknown function (DUF2922)
MEPHMAFF_00580 4.9e-31
MEPHMAFF_00581 5.5e-120 recX 2.4.1.337 GT4 S Regulatory protein RecX
MEPHMAFF_00582 2.1e-145 cps1D M Domain of unknown function (DUF4422)
MEPHMAFF_00583 2.4e-175 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MEPHMAFF_00584 5e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
MEPHMAFF_00585 5.8e-216 glf 5.4.99.9 M UDP-galactopyranose mutase
MEPHMAFF_00586 8.1e-238 L Transposase
MEPHMAFF_00587 2.1e-239 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
MEPHMAFF_00588 8.8e-150 waaB GT4 M Glycosyl transferases group 1
MEPHMAFF_00589 2.8e-132 M transferase activity, transferring glycosyl groups
MEPHMAFF_00590 2.9e-101 acmD M repeat protein
MEPHMAFF_00592 6.9e-102 S enterobacterial common antigen metabolic process
MEPHMAFF_00593 2.5e-185 cps3F
MEPHMAFF_00594 6.6e-84 M biosynthesis protein
MEPHMAFF_00595 2.4e-264 L PFAM Integrase catalytic region
MEPHMAFF_00596 3.6e-10
MEPHMAFF_00597 1.5e-49 M KxYKxGKxW signal domain protein
MEPHMAFF_00599 1.2e-190 L PFAM Integrase catalytic region
MEPHMAFF_00600 6.6e-218 L Transposase
MEPHMAFF_00601 3.3e-62 L Transposase IS66 family
MEPHMAFF_00602 8.3e-111 L Transposase IS66 family
MEPHMAFF_00603 7.6e-230 L Integrase core domain
MEPHMAFF_00604 1.2e-137 L Bacterial dnaA protein
MEPHMAFF_00605 5.6e-81 L Transposase IS66 family
MEPHMAFF_00606 2e-61 XK27_01125 L PFAM IS66 Orf2 family protein
MEPHMAFF_00608 4.3e-250 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEPHMAFF_00609 2.3e-110 M repeat protein
MEPHMAFF_00610 9.7e-26
MEPHMAFF_00611 3.7e-126 M Glycosyltransferase like family 2
MEPHMAFF_00612 1e-105 L PFAM Integrase catalytic region
MEPHMAFF_00613 1.4e-38 L PFAM Integrase catalytic region
MEPHMAFF_00614 4e-44 S dextransucrase activity
MEPHMAFF_00615 1.5e-160 yueF S AI-2E family transporter
MEPHMAFF_00616 1e-162 S Psort location CytoplasmicMembrane, score
MEPHMAFF_00617 1.2e-27 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEPHMAFF_00618 6.4e-190 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEPHMAFF_00619 5.6e-227 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MEPHMAFF_00620 1.3e-309 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MEPHMAFF_00621 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_00622 1.3e-34 L PFAM Integrase catalytic region
MEPHMAFF_00623 2e-146 L PFAM Integrase catalytic region
MEPHMAFF_00624 9.3e-65 gntR1 K Transcriptional regulator, GntR family
MEPHMAFF_00625 3.6e-157 V ABC transporter, ATP-binding protein
MEPHMAFF_00626 6.7e-114
MEPHMAFF_00627 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
MEPHMAFF_00628 2.4e-99 S Pfam:DUF3816
MEPHMAFF_00629 0.0 clpE O Belongs to the ClpA ClpB family
MEPHMAFF_00630 2.9e-27
MEPHMAFF_00631 2.7e-39 ptsH G phosphocarrier protein HPR
MEPHMAFF_00632 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEPHMAFF_00633 1.4e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MEPHMAFF_00634 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
MEPHMAFF_00635 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEPHMAFF_00636 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
MEPHMAFF_00648 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
MEPHMAFF_00649 1.5e-237 lmrB EGP Major facilitator Superfamily
MEPHMAFF_00650 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MEPHMAFF_00651 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEPHMAFF_00652 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
MEPHMAFF_00653 2.6e-80 lytE M LysM domain protein
MEPHMAFF_00654 0.0 oppD EP Psort location Cytoplasmic, score
MEPHMAFF_00655 2.3e-93 lytE M LysM domain protein
MEPHMAFF_00656 6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
MEPHMAFF_00657 6.9e-167 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MEPHMAFF_00658 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
MEPHMAFF_00659 8.1e-154 yeaE S Aldo keto
MEPHMAFF_00660 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
MEPHMAFF_00661 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
MEPHMAFF_00662 2.9e-78 S Psort location Cytoplasmic, score
MEPHMAFF_00663 7.7e-86 S Short repeat of unknown function (DUF308)
MEPHMAFF_00664 1e-23
MEPHMAFF_00665 2.8e-102 V VanZ like family
MEPHMAFF_00666 2.6e-147 cycA E Amino acid permease
MEPHMAFF_00667 5e-77 cycA E Amino acid permease
MEPHMAFF_00668 4.3e-85 perR P Belongs to the Fur family
MEPHMAFF_00669 5e-236 EGP Major facilitator Superfamily
MEPHMAFF_00670 9.6e-92 tag 3.2.2.20 L glycosylase
MEPHMAFF_00671 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEPHMAFF_00672 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEPHMAFF_00673 4.9e-41
MEPHMAFF_00674 4.1e-303 ytgP S Polysaccharide biosynthesis protein
MEPHMAFF_00675 8.9e-237 L Transposase
MEPHMAFF_00676 6.5e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MEPHMAFF_00677 5.6e-277 pepV 3.5.1.18 E dipeptidase PepV
MEPHMAFF_00678 1.2e-85 uspA T Belongs to the universal stress protein A family
MEPHMAFF_00679 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEPHMAFF_00680 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
MEPHMAFF_00681 3.8e-113
MEPHMAFF_00682 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
MEPHMAFF_00683 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEPHMAFF_00684 2.1e-32
MEPHMAFF_00685 4.5e-112 S CAAX protease self-immunity
MEPHMAFF_00686 1.9e-43
MEPHMAFF_00688 1.8e-105 L Belongs to the 'phage' integrase family
MEPHMAFF_00689 2.3e-16
MEPHMAFF_00690 3.8e-34 S Membrane
MEPHMAFF_00691 2.7e-20 E Zn peptidase
MEPHMAFF_00692 4.6e-41 xre K Helix-turn-helix XRE-family like proteins
MEPHMAFF_00694 8.8e-94 K BRO family, N-terminal domain
MEPHMAFF_00695 3.4e-26 S Domain of unknown function (DUF771)
MEPHMAFF_00700 2.7e-51 S ERF superfamily
MEPHMAFF_00701 2.6e-14 L Single-strand binding protein family
MEPHMAFF_00702 2e-26 ybl78 L DnaD domain protein
MEPHMAFF_00703 2.9e-55 dnaC 3.4.21.53 L IstB-like ATP binding protein
MEPHMAFF_00706 3.2e-52 S Protein of unknown function (DUF1064)
MEPHMAFF_00711 2.1e-18
MEPHMAFF_00712 9.2e-21
MEPHMAFF_00716 1.1e-33
MEPHMAFF_00720 1.7e-74 V HNH nucleases
MEPHMAFF_00721 5.6e-92 L Phage terminase, small subunit
MEPHMAFF_00722 0.0 S Phage Terminase
MEPHMAFF_00723 8.6e-218 S Phage portal protein
MEPHMAFF_00724 8.5e-292 S Phage capsid family
MEPHMAFF_00725 6.8e-08
MEPHMAFF_00726 8.7e-60 S Phage head-tail joining protein
MEPHMAFF_00727 2.7e-68 S Bacteriophage HK97-gp10, putative tail-component
MEPHMAFF_00728 4e-63 S Protein of unknown function (DUF806)
MEPHMAFF_00729 2.1e-126 S Phage tail tube protein
MEPHMAFF_00730 3.8e-64 S Phage tail assembly chaperone proteins, TAC
MEPHMAFF_00731 2.1e-27 M Phage tail tape measure protein TP901
MEPHMAFF_00732 1.6e-301 M Phage tail tape measure protein TP901
MEPHMAFF_00733 3.8e-159 S Phage tail protein
MEPHMAFF_00734 7.1e-280 M Prophage endopeptidase tail
MEPHMAFF_00735 4.7e-33
MEPHMAFF_00737 3.3e-27
MEPHMAFF_00740 1.4e-11
MEPHMAFF_00741 2.5e-33
MEPHMAFF_00742 2.9e-52 S Bacteriophage holin of superfamily 6 (Holin_LLH)
MEPHMAFF_00743 8.1e-155 M Glycosyl hydrolases family 25
MEPHMAFF_00744 1.9e-11 T PFAM SpoVT AbrB
MEPHMAFF_00745 2.7e-23 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MEPHMAFF_00746 1.9e-68
MEPHMAFF_00747 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MEPHMAFF_00748 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MEPHMAFF_00749 3.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
MEPHMAFF_00750 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MEPHMAFF_00751 1.1e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
MEPHMAFF_00752 9.3e-217 folP 2.5.1.15 H dihydropteroate synthase
MEPHMAFF_00753 1.8e-43
MEPHMAFF_00754 3.3e-40
MEPHMAFF_00756 7.9e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MEPHMAFF_00757 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MEPHMAFF_00758 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MEPHMAFF_00759 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MEPHMAFF_00760 3.5e-40 yheA S Belongs to the UPF0342 family
MEPHMAFF_00761 1.8e-220 yhaO L Ser Thr phosphatase family protein
MEPHMAFF_00762 0.0 L AAA domain
MEPHMAFF_00763 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MEPHMAFF_00765 2.7e-76 hit FG histidine triad
MEPHMAFF_00766 3.9e-136 ecsA V ABC transporter, ATP-binding protein
MEPHMAFF_00767 1.1e-217 ecsB U ABC transporter
MEPHMAFF_00768 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEPHMAFF_00769 7.7e-27 S YSIRK type signal peptide
MEPHMAFF_00770 3.8e-66 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
MEPHMAFF_00771 3.4e-253 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
MEPHMAFF_00772 2.3e-145 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MEPHMAFF_00773 1.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MEPHMAFF_00774 8.8e-184 iolS C Aldo keto reductase
MEPHMAFF_00775 9.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
MEPHMAFF_00776 7.5e-58 ytzB S Small secreted protein
MEPHMAFF_00777 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MEPHMAFF_00778 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEPHMAFF_00779 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
MEPHMAFF_00780 1.3e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MEPHMAFF_00781 1.9e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MEPHMAFF_00782 1.9e-119 ybhL S Belongs to the BI1 family
MEPHMAFF_00783 4.1e-116 yoaK S Protein of unknown function (DUF1275)
MEPHMAFF_00784 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEPHMAFF_00785 2.2e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MEPHMAFF_00786 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEPHMAFF_00787 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MEPHMAFF_00788 1.4e-203 dnaB L replication initiation and membrane attachment
MEPHMAFF_00789 1.1e-170 dnaI L Primosomal protein DnaI
MEPHMAFF_00790 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MEPHMAFF_00791 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MEPHMAFF_00792 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEPHMAFF_00793 1.8e-95 yqeG S HAD phosphatase, family IIIA
MEPHMAFF_00794 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
MEPHMAFF_00795 1.9e-47 yhbY J RNA-binding protein
MEPHMAFF_00796 6.2e-122 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEPHMAFF_00797 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MEPHMAFF_00798 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEPHMAFF_00799 1.7e-139 yqeM Q Methyltransferase
MEPHMAFF_00800 6.1e-213 ylbM S Belongs to the UPF0348 family
MEPHMAFF_00801 2.9e-99 yceD S Uncharacterized ACR, COG1399
MEPHMAFF_00802 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MEPHMAFF_00803 6.2e-190 L PFAM Integrase catalytic region
MEPHMAFF_00804 1.5e-121 K response regulator
MEPHMAFF_00805 4.1e-278 arlS 2.7.13.3 T Histidine kinase
MEPHMAFF_00806 7.4e-267 yjeM E Amino Acid
MEPHMAFF_00807 1.3e-262 L Transposase
MEPHMAFF_00808 4.4e-231 V MatE
MEPHMAFF_00809 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MEPHMAFF_00810 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEPHMAFF_00811 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MEPHMAFF_00812 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEPHMAFF_00813 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MEPHMAFF_00814 2e-58 yodB K Transcriptional regulator, HxlR family
MEPHMAFF_00815 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEPHMAFF_00816 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEPHMAFF_00817 5.6e-115 rlpA M PFAM NLP P60 protein
MEPHMAFF_00818 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
MEPHMAFF_00819 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEPHMAFF_00820 3.7e-75 L PFAM transposase IS200-family protein
MEPHMAFF_00821 8.8e-71 yneR S Belongs to the HesB IscA family
MEPHMAFF_00822 0.0 S membrane
MEPHMAFF_00823 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MEPHMAFF_00824 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MEPHMAFF_00825 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MEPHMAFF_00826 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
MEPHMAFF_00827 1.1e-45 gluP 3.4.21.105 S Peptidase, S54 family
MEPHMAFF_00828 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
MEPHMAFF_00829 5.6e-183 glk 2.7.1.2 G Glucokinase
MEPHMAFF_00830 3.4e-67 yqhL P Rhodanese-like protein
MEPHMAFF_00831 5.9e-22 S Protein of unknown function (DUF3042)
MEPHMAFF_00832 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEPHMAFF_00833 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
MEPHMAFF_00834 3.4e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEPHMAFF_00835 4.8e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MEPHMAFF_00836 3.9e-12
MEPHMAFF_00837 3.1e-153 P Belongs to the nlpA lipoprotein family
MEPHMAFF_00839 6e-78 L Belongs to the 'phage' integrase family
MEPHMAFF_00840 2.1e-10 E Zn peptidase
MEPHMAFF_00841 1.9e-18 S protein disulfide oxidoreductase activity
MEPHMAFF_00844 2e-18 L Psort location Cytoplasmic, score
MEPHMAFF_00853 9.3e-69 L Helix-turn-helix domain
MEPHMAFF_00854 9e-137 L hmm pf00665
MEPHMAFF_00858 1.7e-12
MEPHMAFF_00864 7.5e-65 ruvB 3.6.4.12 L four-way junction helicase activity
MEPHMAFF_00867 1e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MEPHMAFF_00868 9.4e-11 T PFAM SpoVT AbrB
MEPHMAFF_00871 3.1e-70
MEPHMAFF_00874 1e-170 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEPHMAFF_00875 7.1e-97 papP P ABC transporter, permease protein
MEPHMAFF_00876 2.1e-96 P ABC transporter permease
MEPHMAFF_00877 3.7e-118 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEPHMAFF_00878 5e-135 cjaA ET ABC transporter substrate-binding protein
MEPHMAFF_00879 2.8e-168 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEPHMAFF_00880 8.8e-19 D nuclear chromosome segregation
MEPHMAFF_00881 1.8e-148 V Type I restriction-modification system methyltransferase subunit()
MEPHMAFF_00882 8.7e-36 3.1.21.3 V Type I restriction modification DNA specificity domain
MEPHMAFF_00883 1.5e-92 L Belongs to the 'phage' integrase family
MEPHMAFF_00886 2.7e-32 XK27_00515 D Glucan-binding protein C
MEPHMAFF_00887 1.6e-16 K ORF6N domain
MEPHMAFF_00890 1e-08 nrdH O Glutaredoxin-like protein NrdH
MEPHMAFF_00891 3.5e-51 L Protein of unknown function (DUF3991)
MEPHMAFF_00892 2e-11 K PFAM helix-turn-helix domain protein
MEPHMAFF_00893 7e-143 topA2 5.99.1.2 G Topoisomerase IA
MEPHMAFF_00896 1.8e-145 clpB O Belongs to the ClpA ClpB family
MEPHMAFF_00901 3.6e-233 U TraM recognition site of TraD and TraG
MEPHMAFF_00902 9.8e-68
MEPHMAFF_00904 6.5e-29
MEPHMAFF_00905 9.7e-195 U type IV secretory pathway VirB4
MEPHMAFF_00907 4.3e-44 M Prophage endopeptidase tail
MEPHMAFF_00910 1.1e-07 V CAAX protease self-immunity
MEPHMAFF_00911 1.5e-258 S Uncharacterised protein family (UPF0236)
MEPHMAFF_00912 5.3e-191 P ammonium transporter
MEPHMAFF_00913 1.7e-85 ureI S AmiS/UreI family transporter
MEPHMAFF_00914 2.3e-42 ureA 3.5.1.5 E Urease, gamma subunit
MEPHMAFF_00915 7e-44 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MEPHMAFF_00916 5.3e-293 ureC 3.5.1.5 E Amidohydrolase family
MEPHMAFF_00917 9.4e-56 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MEPHMAFF_00918 2.9e-96 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MEPHMAFF_00919 1.3e-97 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MEPHMAFF_00920 1.4e-92 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MEPHMAFF_00921 2.9e-18 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEPHMAFF_00922 2.2e-24 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEPHMAFF_00923 7.3e-65 yhiD S MgtC family
MEPHMAFF_00924 1e-131 nikMN P PDGLE domain
MEPHMAFF_00925 1.1e-46 P Cobalt transport protein
MEPHMAFF_00926 4.9e-99 cbiO P ABC transporter
MEPHMAFF_00927 3.5e-11 ytgP S Polysaccharide biosynthesis protein
MEPHMAFF_00928 1.2e-76 S Fic/DOC family
MEPHMAFF_00929 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEPHMAFF_00930 1.4e-50 S Iron-sulfur cluster assembly protein
MEPHMAFF_00931 1e-151
MEPHMAFF_00932 6.6e-174
MEPHMAFF_00933 2.5e-89 dut S Protein conserved in bacteria
MEPHMAFF_00937 8.3e-111 K Transcriptional regulator
MEPHMAFF_00938 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
MEPHMAFF_00939 1.6e-54 ysxB J Cysteine protease Prp
MEPHMAFF_00940 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MEPHMAFF_00941 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MEPHMAFF_00942 6.6e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MEPHMAFF_00943 8.6e-114 J 2'-5' RNA ligase superfamily
MEPHMAFF_00944 2.2e-70 yqhY S Asp23 family, cell envelope-related function
MEPHMAFF_00945 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MEPHMAFF_00946 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEPHMAFF_00947 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEPHMAFF_00948 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEPHMAFF_00949 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MEPHMAFF_00950 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MEPHMAFF_00951 3.3e-77 argR K Regulates arginine biosynthesis genes
MEPHMAFF_00952 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
MEPHMAFF_00953 1.7e-54
MEPHMAFF_00954 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MEPHMAFF_00955 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MEPHMAFF_00956 6.9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MEPHMAFF_00957 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEPHMAFF_00958 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEPHMAFF_00959 9.6e-250 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MEPHMAFF_00960 2.9e-131 stp 3.1.3.16 T phosphatase
MEPHMAFF_00961 0.0 KLT serine threonine protein kinase
MEPHMAFF_00962 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEPHMAFF_00963 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MEPHMAFF_00964 1.8e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
MEPHMAFF_00965 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MEPHMAFF_00966 4.7e-58 asp S Asp23 family, cell envelope-related function
MEPHMAFF_00967 0.0 yloV S DAK2 domain fusion protein YloV
MEPHMAFF_00968 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MEPHMAFF_00969 4e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MEPHMAFF_00970 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEPHMAFF_00971 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEPHMAFF_00972 0.0 smc D Required for chromosome condensation and partitioning
MEPHMAFF_00973 4.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEPHMAFF_00974 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MEPHMAFF_00975 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEPHMAFF_00976 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MEPHMAFF_00977 2e-39 ylqC S Belongs to the UPF0109 family
MEPHMAFF_00978 9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MEPHMAFF_00979 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MEPHMAFF_00980 4.9e-260 yfnA E amino acid
MEPHMAFF_00981 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEPHMAFF_00982 9.3e-69 L Helix-turn-helix domain
MEPHMAFF_00983 9e-137 L hmm pf00665
MEPHMAFF_00984 3.6e-190 L PFAM Integrase catalytic region
MEPHMAFF_00985 3.1e-237 L Transposase
MEPHMAFF_00986 2.9e-34
MEPHMAFF_00987 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
MEPHMAFF_00988 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
MEPHMAFF_00989 3.3e-83
MEPHMAFF_00990 2.4e-264 L PFAM Integrase catalytic region
MEPHMAFF_00991 1.5e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MEPHMAFF_00992 7.8e-155 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MEPHMAFF_00993 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MEPHMAFF_00994 2.4e-223 mdtG EGP Major facilitator Superfamily
MEPHMAFF_00995 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
MEPHMAFF_00996 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEPHMAFF_00997 8.1e-238 L Transposase
MEPHMAFF_01000 3e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MEPHMAFF_01001 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MEPHMAFF_01002 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
MEPHMAFF_01003 0.0 trxB2 1.8.1.9 C Thioredoxin domain
MEPHMAFF_01004 2.4e-264 L PFAM Integrase catalytic region
MEPHMAFF_01005 1.3e-180 M LPXTG-motif cell wall anchor domain protein
MEPHMAFF_01006 0.0 M LPXTG-motif cell wall anchor domain protein
MEPHMAFF_01007 1.1e-19 M LPXTG-motif cell wall anchor domain protein
MEPHMAFF_01009 2.6e-191 nss M transferase activity, transferring glycosyl groups
MEPHMAFF_01010 1.1e-143 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
MEPHMAFF_01011 2.6e-195 M transferase activity, transferring glycosyl groups
MEPHMAFF_01012 2.4e-217 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
MEPHMAFF_01013 4.5e-155 asp3 S Accessory Sec secretory system ASP3
MEPHMAFF_01014 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEPHMAFF_01015 4.2e-225 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MEPHMAFF_01016 7.9e-196 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MEPHMAFF_01018 3.6e-17 sraP UW this gene contains a nucleotide ambiguity which may be the result of a sequencing error
MEPHMAFF_01019 6.8e-08 UW Hep Hag repeat protein
MEPHMAFF_01020 1.7e-103 O Bacterial dnaA protein
MEPHMAFF_01021 9.8e-217 L Integrase core domain
MEPHMAFF_01022 5.6e-277 pipD E Dipeptidase
MEPHMAFF_01023 0.0 yjbQ P TrkA C-terminal domain protein
MEPHMAFF_01024 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MEPHMAFF_01025 6.6e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MEPHMAFF_01026 3.4e-83
MEPHMAFF_01027 6.6e-37
MEPHMAFF_01028 1.9e-62 K DNA-templated transcription, initiation
MEPHMAFF_01029 6.7e-41 K Transcriptional regulator, HxlR family
MEPHMAFF_01030 1.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MEPHMAFF_01031 2.6e-139 epsB M biosynthesis protein
MEPHMAFF_01032 3.4e-119 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MEPHMAFF_01033 8.3e-106 rfbP M Bacterial sugar transferase
MEPHMAFF_01034 2.2e-73 cpsF M Oligosaccharide biosynthesis protein Alg14 like
MEPHMAFF_01035 3e-47 pssE S Glycosyltransferase family 28 C-terminal domain
MEPHMAFF_01036 6.3e-16 cps3F
MEPHMAFF_01037 8.4e-60 M Glycosyltransferase group 2 family protein
MEPHMAFF_01038 1.4e-72 M Glycosyltransferase like family 2
MEPHMAFF_01039 1.2e-117 S Polysaccharide biosynthesis protein
MEPHMAFF_01040 1.6e-52 MA20_43635 M Capsular polysaccharide synthesis protein
MEPHMAFF_01041 1.9e-89 tagB 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MEPHMAFF_01042 8.9e-65 S Core-2/I-Branching enzyme
MEPHMAFF_01043 1.9e-90 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MEPHMAFF_01044 6.2e-87 4.2.1.46 GM Male sterility protein
MEPHMAFF_01045 1e-170 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEPHMAFF_01046 2e-216 glf 5.4.99.9 M UDP-galactopyranose mutase
MEPHMAFF_01047 7.5e-217 L Integrase core domain
MEPHMAFF_01048 1.7e-103 O Bacterial dnaA protein
MEPHMAFF_01049 1.7e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEPHMAFF_01051 4.3e-144 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MEPHMAFF_01052 3.8e-249 mmuP E amino acid
MEPHMAFF_01054 2.1e-60 L PFAM transposase IS200-family protein
MEPHMAFF_01055 6.9e-228 L transposase, IS605 OrfB family
MEPHMAFF_01056 1.5e-34 T Toxin-antitoxin system, toxin component, MazF family
MEPHMAFF_01057 1e-37
MEPHMAFF_01058 5.2e-07 D nuclear chromosome segregation
MEPHMAFF_01059 0.0 snf 2.7.11.1 KL domain protein
MEPHMAFF_01060 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
MEPHMAFF_01061 4.4e-177 M Glycosyl hydrolases family 25
MEPHMAFF_01062 2.2e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MEPHMAFF_01063 0.0 sbcC L Putative exonuclease SbcCD, C subunit
MEPHMAFF_01064 2.4e-92 L nuclease
MEPHMAFF_01065 1.9e-105 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_01066 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
MEPHMAFF_01067 3.3e-71
MEPHMAFF_01068 4.5e-100 fic D Fic/DOC family
MEPHMAFF_01069 2.6e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MEPHMAFF_01070 7e-150 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MEPHMAFF_01071 1e-31
MEPHMAFF_01072 5.8e-43
MEPHMAFF_01073 1.8e-99
MEPHMAFF_01074 7.1e-25
MEPHMAFF_01076 7.6e-112 lssY 3.6.1.27 I Acid phosphatase homologues
MEPHMAFF_01077 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MEPHMAFF_01078 2e-228 clcA_2 P Chloride transporter, ClC family
MEPHMAFF_01079 2e-115 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MEPHMAFF_01080 5.7e-115 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MEPHMAFF_01081 3.7e-19 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MEPHMAFF_01082 1e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MEPHMAFF_01083 1.8e-50
MEPHMAFF_01084 0.0 S SEC-C Motif Domain Protein
MEPHMAFF_01085 3.4e-171 L Integrase core domain
MEPHMAFF_01086 1.9e-46 L Transposase
MEPHMAFF_01087 1.4e-72
MEPHMAFF_01088 8.9e-173
MEPHMAFF_01089 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_01090 4.8e-177 fecB P Periplasmic binding protein
MEPHMAFF_01091 1.4e-139 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
MEPHMAFF_01092 4.1e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEPHMAFF_01093 1.5e-77 S Flavodoxin
MEPHMAFF_01094 3.7e-64 moaE 2.8.1.12 H MoaE protein
MEPHMAFF_01095 4.9e-35 moaD 2.8.1.12 H ThiS family
MEPHMAFF_01096 3.9e-218 narK P Transporter, major facilitator family protein
MEPHMAFF_01097 2.9e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
MEPHMAFF_01098 3.6e-182
MEPHMAFF_01099 1.6e-18
MEPHMAFF_01100 2.3e-116 nreC K PFAM regulatory protein LuxR
MEPHMAFF_01101 2.3e-190 comP 2.7.13.3 F Sensor histidine kinase
MEPHMAFF_01102 3e-44
MEPHMAFF_01103 4.7e-105 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MEPHMAFF_01104 5.1e-84 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MEPHMAFF_01105 8.5e-229 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
MEPHMAFF_01106 5.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MEPHMAFF_01107 2.6e-186 moeB 2.7.7.73, 2.7.7.80 H ThiF family
MEPHMAFF_01108 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MEPHMAFF_01109 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
MEPHMAFF_01110 2.7e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
MEPHMAFF_01111 2.5e-129 narI 1.7.5.1 C Nitrate reductase
MEPHMAFF_01112 4.1e-164 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MEPHMAFF_01113 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_01114 1.2e-152 EG EamA-like transporter family
MEPHMAFF_01115 2.5e-118 L Integrase
MEPHMAFF_01116 1.4e-158 rssA S Phospholipase, patatin family
MEPHMAFF_01117 2.5e-240 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
MEPHMAFF_01118 9.6e-200 xerS L Belongs to the 'phage' integrase family
MEPHMAFF_01120 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEPHMAFF_01121 4.2e-77 marR K Transcriptional regulator, MarR family
MEPHMAFF_01122 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEPHMAFF_01123 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEPHMAFF_01124 1.2e-158 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MEPHMAFF_01125 4.2e-130 IQ reductase
MEPHMAFF_01126 1.2e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEPHMAFF_01127 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEPHMAFF_01128 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEPHMAFF_01129 3e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MEPHMAFF_01130 5.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MEPHMAFF_01131 1.1e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MEPHMAFF_01132 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MEPHMAFF_01137 3.1e-237 L Transposase
MEPHMAFF_01138 2e-169 L Transposase and inactivated derivatives IS30 family
MEPHMAFF_01139 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_01144 4e-28 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEPHMAFF_01145 9.3e-189 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEPHMAFF_01146 1.4e-51
MEPHMAFF_01147 1.1e-113 frnE Q DSBA-like thioredoxin domain
MEPHMAFF_01148 1.7e-78 I alpha/beta hydrolase fold
MEPHMAFF_01149 8.5e-20 K Helix-turn-helix XRE-family like proteins
MEPHMAFF_01150 1.1e-35 S Phage derived protein Gp49-like (DUF891)
MEPHMAFF_01152 1.6e-45 yrvD S Pfam:DUF1049
MEPHMAFF_01153 5.6e-155 3.1.3.102, 3.1.3.104 S hydrolase
MEPHMAFF_01154 8.1e-90 ntd 2.4.2.6 F Nucleoside
MEPHMAFF_01155 3.7e-20
MEPHMAFF_01156 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
MEPHMAFF_01157 6.2e-114 yviA S Protein of unknown function (DUF421)
MEPHMAFF_01158 9.1e-72 S Protein of unknown function (DUF3290)
MEPHMAFF_01159 7e-41 ybaN S Protein of unknown function (DUF454)
MEPHMAFF_01160 3.1e-237 L Transposase
MEPHMAFF_01161 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEPHMAFF_01162 5.5e-158 endA V DNA/RNA non-specific endonuclease
MEPHMAFF_01163 1e-254 yifK E Amino acid permease
MEPHMAFF_01165 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEPHMAFF_01166 1.3e-229 N Uncharacterized conserved protein (DUF2075)
MEPHMAFF_01167 4.6e-123 S SNARE associated Golgi protein
MEPHMAFF_01168 0.0 uvrA3 L excinuclease ABC, A subunit
MEPHMAFF_01169 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEPHMAFF_01170 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEPHMAFF_01171 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEPHMAFF_01172 9.6e-144 S DUF218 domain
MEPHMAFF_01173 0.0 ubiB S ABC1 family
MEPHMAFF_01174 2.5e-245 yhdP S Transporter associated domain
MEPHMAFF_01175 8.1e-238 L Transposase
MEPHMAFF_01176 5e-75 copY K Copper transport repressor CopY TcrY
MEPHMAFF_01177 1.3e-244 EGP Major facilitator Superfamily
MEPHMAFF_01178 1e-73 yeaL S UPF0756 membrane protein
MEPHMAFF_01179 5.6e-79 yphH S Cupin domain
MEPHMAFF_01180 3.2e-83 C Flavodoxin
MEPHMAFF_01181 1.1e-158 K LysR substrate binding domain protein
MEPHMAFF_01182 1.9e-169 1.1.1.346 C Aldo keto reductase
MEPHMAFF_01183 2.1e-39 gcvR T Belongs to the UPF0237 family
MEPHMAFF_01184 8.5e-73 XK27_08635 S UPF0210 protein
MEPHMAFF_01185 5.1e-151 XK27_08635 S UPF0210 protein
MEPHMAFF_01186 1.5e-94 K Acetyltransferase (GNAT) domain
MEPHMAFF_01187 1.2e-160 S Alpha beta hydrolase
MEPHMAFF_01188 1.1e-158 gspA M family 8
MEPHMAFF_01189 6.6e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MEPHMAFF_01190 3.8e-93
MEPHMAFF_01191 2.4e-161 degV S EDD domain protein, DegV family
MEPHMAFF_01192 0.0 FbpA K Fibronectin-binding protein
MEPHMAFF_01193 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MEPHMAFF_01194 6.2e-207 carA 6.3.5.5 F Belongs to the CarA family
MEPHMAFF_01195 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MEPHMAFF_01196 1.3e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEPHMAFF_01197 1.5e-65 esbA S Family of unknown function (DUF5322)
MEPHMAFF_01198 4.4e-70 rnhA 3.1.26.4 L Ribonuclease HI
MEPHMAFF_01199 2.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MEPHMAFF_01200 1.4e-259 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEPHMAFF_01201 3.8e-84 F Belongs to the NrdI family
MEPHMAFF_01202 3.1e-237 L Transposase
MEPHMAFF_01203 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MEPHMAFF_01204 2.6e-103 ypsA S Belongs to the UPF0398 family
MEPHMAFF_01205 7.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MEPHMAFF_01206 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MEPHMAFF_01207 3.9e-162 EG EamA-like transporter family
MEPHMAFF_01208 3e-125 dnaD L DnaD domain protein
MEPHMAFF_01209 9e-87 ypmB S Protein conserved in bacteria
MEPHMAFF_01210 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MEPHMAFF_01211 1.5e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MEPHMAFF_01212 1.4e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MEPHMAFF_01213 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MEPHMAFF_01214 3.4e-194 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MEPHMAFF_01215 4.9e-87 S Protein of unknown function (DUF1440)
MEPHMAFF_01216 0.0 rafA 3.2.1.22 G alpha-galactosidase
MEPHMAFF_01217 9.5e-53 K purine nucleotide biosynthetic process
MEPHMAFF_01218 7.4e-230 L transposase, IS605 OrfB family
MEPHMAFF_01219 2.1e-60 L PFAM transposase IS200-family protein
MEPHMAFF_01220 1.2e-131 galR K Periplasmic binding protein-like domain
MEPHMAFF_01221 5.3e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MEPHMAFF_01222 7.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MEPHMAFF_01223 2.6e-124 lrgB M LrgB-like family
MEPHMAFF_01224 1.9e-66 lrgA S LrgA family
MEPHMAFF_01225 2.4e-130 lytT K response regulator receiver
MEPHMAFF_01226 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
MEPHMAFF_01227 4e-148 f42a O Band 7 protein
MEPHMAFF_01228 3e-259 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MEPHMAFF_01229 2.2e-156 yitU 3.1.3.104 S hydrolase
MEPHMAFF_01230 9.2e-39 S Cytochrome B5
MEPHMAFF_01231 9.8e-115 nreC K PFAM regulatory protein LuxR
MEPHMAFF_01232 6.1e-160 hipB K Helix-turn-helix
MEPHMAFF_01233 2.8e-57 yitW S Iron-sulfur cluster assembly protein
MEPHMAFF_01234 1.6e-271 sufB O assembly protein SufB
MEPHMAFF_01235 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
MEPHMAFF_01236 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MEPHMAFF_01237 7.3e-239 sufD O FeS assembly protein SufD
MEPHMAFF_01238 6.5e-145 sufC O FeS assembly ATPase SufC
MEPHMAFF_01239 4.2e-32 feoA P FeoA domain
MEPHMAFF_01240 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MEPHMAFF_01241 8e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MEPHMAFF_01242 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MEPHMAFF_01243 3.5e-64 ydiI Q Thioesterase superfamily
MEPHMAFF_01244 5.4e-109 yvrI K sigma factor activity
MEPHMAFF_01245 5e-202 G Transporter, major facilitator family protein
MEPHMAFF_01246 0.0 S Bacterial membrane protein YfhO
MEPHMAFF_01247 2.1e-102 T Ion transport 2 domain protein
MEPHMAFF_01248 1.7e-76 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MEPHMAFF_01249 2.9e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MEPHMAFF_01250 6.7e-94 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
MEPHMAFF_01251 5.3e-187 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MEPHMAFF_01252 2.4e-264 L PFAM Integrase catalytic region
MEPHMAFF_01253 1.5e-180 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MEPHMAFF_01254 3.3e-230 L transposase, IS605 OrfB family
MEPHMAFF_01255 2.1e-60 L PFAM transposase IS200-family protein
MEPHMAFF_01257 0.0 L PLD-like domain
MEPHMAFF_01258 4.3e-36 higA K addiction module antidote protein HigA
MEPHMAFF_01259 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MEPHMAFF_01260 3.3e-110 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MEPHMAFF_01261 3.9e-120 xerC L Belongs to the 'phage' integrase family
MEPHMAFF_01262 4.6e-45 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MEPHMAFF_01263 5.1e-37 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
MEPHMAFF_01264 2.3e-300 2.1.1.72 V type I restriction-modification system
MEPHMAFF_01265 1.7e-177 yfjM S Protein of unknown function DUF262
MEPHMAFF_01266 3.1e-57 yhaI S Protein of unknown function (DUF805)
MEPHMAFF_01267 8.1e-238 L Transposase
MEPHMAFF_01268 2.2e-44
MEPHMAFF_01269 3.1e-22
MEPHMAFF_01270 5.4e-47
MEPHMAFF_01271 3.7e-96 K Acetyltransferase (GNAT) domain
MEPHMAFF_01272 2.9e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MEPHMAFF_01273 8.7e-227 gntT EG Gluconate
MEPHMAFF_01274 2.2e-182 K Transcriptional regulator, LacI family
MEPHMAFF_01275 1.8e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MEPHMAFF_01276 3.2e-95
MEPHMAFF_01277 2.1e-25
MEPHMAFF_01278 1.3e-61 asp S Asp23 family, cell envelope-related function
MEPHMAFF_01279 4.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
MEPHMAFF_01281 2.7e-49
MEPHMAFF_01282 1.6e-67 yqkB S Belongs to the HesB IscA family
MEPHMAFF_01283 2e-261 L PFAM Integrase catalytic region
MEPHMAFF_01284 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
MEPHMAFF_01285 1.7e-84 F NUDIX domain
MEPHMAFF_01286 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEPHMAFF_01287 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEPHMAFF_01288 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MEPHMAFF_01289 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
MEPHMAFF_01290 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEPHMAFF_01291 2.4e-161 dprA LU DNA protecting protein DprA
MEPHMAFF_01292 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEPHMAFF_01293 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MEPHMAFF_01294 4.4e-35 yozE S Belongs to the UPF0346 family
MEPHMAFF_01295 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MEPHMAFF_01296 9.5e-172 ypmR E lipolytic protein G-D-S-L family
MEPHMAFF_01297 1.7e-151 DegV S EDD domain protein, DegV family
MEPHMAFF_01298 5.3e-113 hlyIII S protein, hemolysin III
MEPHMAFF_01299 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MEPHMAFF_01300 7.7e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEPHMAFF_01301 0.0 yfmR S ABC transporter, ATP-binding protein
MEPHMAFF_01302 4.8e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MEPHMAFF_01303 1.5e-236 S Tetratricopeptide repeat protein
MEPHMAFF_01304 5.6e-261 S Uncharacterised protein family (UPF0236)
MEPHMAFF_01305 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEPHMAFF_01306 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MEPHMAFF_01307 2.5e-204 rpsA 1.17.7.4 J Ribosomal protein S1
MEPHMAFF_01308 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MEPHMAFF_01309 8.5e-14 M Lysin motif
MEPHMAFF_01310 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
MEPHMAFF_01311 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
MEPHMAFF_01312 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MEPHMAFF_01313 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MEPHMAFF_01314 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MEPHMAFF_01315 2.2e-137 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MEPHMAFF_01316 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEPHMAFF_01317 1.2e-163 xerD D recombinase XerD
MEPHMAFF_01318 2.3e-167 cvfB S S1 domain
MEPHMAFF_01319 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MEPHMAFF_01320 0.0 dnaE 2.7.7.7 L DNA polymerase
MEPHMAFF_01321 3e-30 S Protein of unknown function (DUF2929)
MEPHMAFF_01322 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MEPHMAFF_01323 3.1e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MEPHMAFF_01324 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
MEPHMAFF_01325 1.2e-219 patA 2.6.1.1 E Aminotransferase
MEPHMAFF_01326 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MEPHMAFF_01327 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEPHMAFF_01328 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MEPHMAFF_01329 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MEPHMAFF_01330 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
MEPHMAFF_01331 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEPHMAFF_01332 9.9e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MEPHMAFF_01333 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEPHMAFF_01334 1.2e-183 phoH T phosphate starvation-inducible protein PhoH
MEPHMAFF_01335 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MEPHMAFF_01336 9.6e-90 bioY S BioY family
MEPHMAFF_01337 3.9e-262 argH 4.3.2.1 E argininosuccinate lyase
MEPHMAFF_01338 2.5e-155 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MEPHMAFF_01339 2.7e-39 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MEPHMAFF_01340 1.5e-183 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEPHMAFF_01341 1.4e-186 L PFAM Integrase catalytic region
MEPHMAFF_01342 3.8e-70 yqeY S YqeY-like protein
MEPHMAFF_01343 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MEPHMAFF_01344 9.1e-265 glnPH2 P ABC transporter permease
MEPHMAFF_01345 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEPHMAFF_01346 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MEPHMAFF_01347 2.1e-165 yniA G Phosphotransferase enzyme family
MEPHMAFF_01348 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEPHMAFF_01349 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEPHMAFF_01350 1.2e-52
MEPHMAFF_01351 2.7e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEPHMAFF_01352 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
MEPHMAFF_01353 4.1e-56
MEPHMAFF_01355 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MEPHMAFF_01357 4e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MEPHMAFF_01358 4.1e-275 pipD E Dipeptidase
MEPHMAFF_01359 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEPHMAFF_01360 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEPHMAFF_01361 0.0 dnaK O Heat shock 70 kDa protein
MEPHMAFF_01362 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEPHMAFF_01363 5.3e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MEPHMAFF_01364 5.8e-64
MEPHMAFF_01365 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MEPHMAFF_01366 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEPHMAFF_01367 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEPHMAFF_01368 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEPHMAFF_01369 4.5e-49 ylxQ J ribosomal protein
MEPHMAFF_01370 1e-44 ylxR K Protein of unknown function (DUF448)
MEPHMAFF_01371 1e-215 nusA K Participates in both transcription termination and antitermination
MEPHMAFF_01372 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
MEPHMAFF_01373 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEPHMAFF_01374 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MEPHMAFF_01375 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MEPHMAFF_01376 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
MEPHMAFF_01377 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEPHMAFF_01378 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEPHMAFF_01379 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MEPHMAFF_01380 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEPHMAFF_01381 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
MEPHMAFF_01382 4.4e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEPHMAFF_01383 5.4e-49 yazA L GIY-YIG catalytic domain protein
MEPHMAFF_01384 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
MEPHMAFF_01385 4.6e-117 plsC 2.3.1.51 I Acyltransferase
MEPHMAFF_01386 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
MEPHMAFF_01387 1.3e-35 ynzC S UPF0291 protein
MEPHMAFF_01388 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MEPHMAFF_01389 6.2e-190 L PFAM Integrase catalytic region
MEPHMAFF_01390 2.4e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MEPHMAFF_01391 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEPHMAFF_01393 7.3e-88
MEPHMAFF_01394 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MEPHMAFF_01395 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MEPHMAFF_01396 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MEPHMAFF_01397 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MEPHMAFF_01398 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEPHMAFF_01399 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEPHMAFF_01400 1.3e-08
MEPHMAFF_01401 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MEPHMAFF_01402 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
MEPHMAFF_01403 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEPHMAFF_01404 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MEPHMAFF_01405 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEPHMAFF_01406 3.5e-163 S Tetratricopeptide repeat
MEPHMAFF_01407 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEPHMAFF_01408 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEPHMAFF_01409 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
MEPHMAFF_01410 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
MEPHMAFF_01411 0.0 comEC S Competence protein ComEC
MEPHMAFF_01412 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
MEPHMAFF_01413 2.6e-80 comEA L Competence protein ComEA
MEPHMAFF_01414 6.7e-198 ylbL T Belongs to the peptidase S16 family
MEPHMAFF_01415 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEPHMAFF_01416 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MEPHMAFF_01417 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MEPHMAFF_01418 2e-222 ftsW D Belongs to the SEDS family
MEPHMAFF_01419 0.0 typA T GTP-binding protein TypA
MEPHMAFF_01420 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MEPHMAFF_01421 1.4e-47 yktA S Belongs to the UPF0223 family
MEPHMAFF_01422 4.1e-275 lpdA 1.8.1.4 C Dehydrogenase
MEPHMAFF_01423 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEPHMAFF_01424 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MEPHMAFF_01425 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MEPHMAFF_01426 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEPHMAFF_01427 2.4e-78
MEPHMAFF_01428 9.8e-32 ykzG S Belongs to the UPF0356 family
MEPHMAFF_01429 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
MEPHMAFF_01430 5.7e-29
MEPHMAFF_01431 1.2e-133 mltD CBM50 M NlpC P60 family protein
MEPHMAFF_01433 7.7e-58
MEPHMAFF_01434 1.7e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MEPHMAFF_01435 3.8e-219 EG GntP family permease
MEPHMAFF_01436 8.5e-84 KT Putative sugar diacid recognition
MEPHMAFF_01437 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEPHMAFF_01438 4.7e-216 patA 2.6.1.1 E Aminotransferase
MEPHMAFF_01439 5.8e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MEPHMAFF_01440 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEPHMAFF_01441 2.5e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MEPHMAFF_01442 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MEPHMAFF_01443 5.1e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MEPHMAFF_01444 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
MEPHMAFF_01445 1.9e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MEPHMAFF_01446 4.3e-25 UW LPXTG-motif cell wall anchor domain protein
MEPHMAFF_01447 4.5e-160 L hmm pf00665
MEPHMAFF_01448 1.1e-73 L Helix-turn-helix domain
MEPHMAFF_01449 2.3e-08 L Helix-turn-helix domain
MEPHMAFF_01450 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEPHMAFF_01451 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MEPHMAFF_01452 9e-119 S Repeat protein
MEPHMAFF_01453 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
MEPHMAFF_01454 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MEPHMAFF_01455 1.3e-57 XK27_04120 S Putative amino acid metabolism
MEPHMAFF_01456 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
MEPHMAFF_01457 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MEPHMAFF_01459 7e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MEPHMAFF_01460 4.2e-32 cspA K Cold shock protein
MEPHMAFF_01461 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEPHMAFF_01462 1.9e-42 divIVA D DivIVA domain protein
MEPHMAFF_01463 5.1e-142 ylmH S S4 domain protein
MEPHMAFF_01464 3.2e-40 yggT S YGGT family
MEPHMAFF_01465 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MEPHMAFF_01466 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEPHMAFF_01467 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MEPHMAFF_01468 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MEPHMAFF_01469 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEPHMAFF_01470 8.5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEPHMAFF_01471 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEPHMAFF_01472 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MEPHMAFF_01473 2.6e-56 ftsL D Cell division protein FtsL
MEPHMAFF_01474 1.4e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEPHMAFF_01475 3.1e-77 mraZ K Belongs to the MraZ family
MEPHMAFF_01476 7.3e-56
MEPHMAFF_01477 1.2e-10 S Protein of unknown function (DUF4044)
MEPHMAFF_01478 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MEPHMAFF_01479 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MEPHMAFF_01480 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
MEPHMAFF_01481 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MEPHMAFF_01485 7.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MEPHMAFF_01486 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEPHMAFF_01487 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
MEPHMAFF_01488 4e-113 yjbH Q Thioredoxin
MEPHMAFF_01489 4.5e-263 pipD E Dipeptidase
MEPHMAFF_01490 3e-203 coiA 3.6.4.12 S Competence protein
MEPHMAFF_01491 2.3e-262 L Transposase
MEPHMAFF_01492 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MEPHMAFF_01493 6.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MEPHMAFF_01494 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MEPHMAFF_01495 4.5e-255 S Uncharacterised protein family (UPF0236)
MEPHMAFF_01496 4e-99 L Transposase
MEPHMAFF_01497 2.9e-93 L Transposase
MEPHMAFF_01498 3.7e-36 L Transposase
MEPHMAFF_01520 5.5e-110 dedA S SNARE-like domain protein
MEPHMAFF_01521 2.4e-105 S Protein of unknown function (DUF1461)
MEPHMAFF_01522 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MEPHMAFF_01523 1.3e-93 yutD S Protein of unknown function (DUF1027)
MEPHMAFF_01524 2.2e-113 S Calcineurin-like phosphoesterase
MEPHMAFF_01525 2.1e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEPHMAFF_01526 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
MEPHMAFF_01528 6.3e-70
MEPHMAFF_01529 2.7e-40
MEPHMAFF_01530 8.3e-78 NU general secretion pathway protein
MEPHMAFF_01531 7.1e-47 comGC U competence protein ComGC
MEPHMAFF_01532 9.5e-181 comGB NU type II secretion system
MEPHMAFF_01533 2.6e-180 comGA NU Type II IV secretion system protein
MEPHMAFF_01534 3.5e-132 yebC K Transcriptional regulatory protein
MEPHMAFF_01535 1.9e-134
MEPHMAFF_01536 1.9e-181 ccpA K catabolite control protein A
MEPHMAFF_01537 3.6e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MEPHMAFF_01538 3.5e-26
MEPHMAFF_01539 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MEPHMAFF_01540 3.4e-147 ykuT M mechanosensitive ion channel
MEPHMAFF_01541 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
MEPHMAFF_01542 3.6e-76 ykuL S (CBS) domain
MEPHMAFF_01543 1.3e-93 S Phosphoesterase
MEPHMAFF_01544 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEPHMAFF_01545 2.7e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MEPHMAFF_01546 1.3e-96 yslB S Protein of unknown function (DUF2507)
MEPHMAFF_01547 6.1e-54 trxA O Belongs to the thioredoxin family
MEPHMAFF_01548 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MEPHMAFF_01549 1e-85 cvpA S Colicin V production protein
MEPHMAFF_01550 6.1e-48 yrzB S Belongs to the UPF0473 family
MEPHMAFF_01551 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEPHMAFF_01552 4.1e-43 yrzL S Belongs to the UPF0297 family
MEPHMAFF_01553 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEPHMAFF_01554 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MEPHMAFF_01555 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MEPHMAFF_01556 1.2e-29 yajC U Preprotein translocase
MEPHMAFF_01557 2.6e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MEPHMAFF_01558 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEPHMAFF_01559 2.5e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEPHMAFF_01560 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEPHMAFF_01561 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MEPHMAFF_01562 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
MEPHMAFF_01563 1.2e-260 S Uncharacterised protein family (UPF0236)
MEPHMAFF_01564 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEPHMAFF_01565 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
MEPHMAFF_01566 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEPHMAFF_01567 7.4e-141 ymfM S Helix-turn-helix domain
MEPHMAFF_01568 3.2e-250 ymfH S Peptidase M16
MEPHMAFF_01569 1.6e-230 ymfF S Peptidase M16 inactive domain protein
MEPHMAFF_01570 2.6e-160 aatB ET ABC transporter substrate-binding protein
MEPHMAFF_01571 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEPHMAFF_01572 3.2e-102 glnP P ABC transporter permease
MEPHMAFF_01573 1.2e-91 mreD M rod shape-determining protein MreD
MEPHMAFF_01574 2.2e-151 mreC M Involved in formation and maintenance of cell shape
MEPHMAFF_01575 1.7e-179 mreB D cell shape determining protein MreB
MEPHMAFF_01576 6.8e-121 radC L DNA repair protein
MEPHMAFF_01577 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MEPHMAFF_01578 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
MEPHMAFF_01579 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MEPHMAFF_01580 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MEPHMAFF_01581 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MEPHMAFF_01582 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
MEPHMAFF_01583 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEPHMAFF_01584 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MEPHMAFF_01585 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
MEPHMAFF_01586 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MEPHMAFF_01587 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEPHMAFF_01588 1.3e-262 L Transposase
MEPHMAFF_01589 1e-235 pbuG S permease
MEPHMAFF_01590 7.1e-106 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MEPHMAFF_01591 1.1e-135 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MEPHMAFF_01592 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
MEPHMAFF_01593 2.5e-135 S Belongs to the UPF0246 family
MEPHMAFF_01594 2.5e-138 S Membrane
MEPHMAFF_01595 1.4e-74 4.4.1.5 E Glyoxalase
MEPHMAFF_01596 1.5e-21
MEPHMAFF_01597 7.1e-86 yueI S Protein of unknown function (DUF1694)
MEPHMAFF_01598 1.7e-235 rarA L recombination factor protein RarA
MEPHMAFF_01599 4.4e-46
MEPHMAFF_01600 4.3e-83 usp6 T universal stress protein
MEPHMAFF_01601 2.8e-207 araR K Transcriptional regulator
MEPHMAFF_01602 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
MEPHMAFF_01603 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
MEPHMAFF_01604 4.4e-171 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MEPHMAFF_01605 1.3e-129 1.1.1.100 I Enoyl-(Acyl carrier protein) reductase
MEPHMAFF_01606 1.8e-39
MEPHMAFF_01607 4.5e-102 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEPHMAFF_01608 7.2e-96 L Helix-turn-helix domain
MEPHMAFF_01609 9.6e-139 L hmm pf00665
MEPHMAFF_01610 1.9e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MEPHMAFF_01611 4e-189 L PFAM Integrase catalytic region
MEPHMAFF_01612 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MEPHMAFF_01613 3.3e-46 gcvH E glycine cleavage
MEPHMAFF_01614 4.1e-220 rodA D Belongs to the SEDS family
MEPHMAFF_01615 1e-31 S Protein of unknown function (DUF2969)
MEPHMAFF_01616 2.9e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MEPHMAFF_01617 9.5e-178 mbl D Cell shape determining protein MreB Mrl
MEPHMAFF_01618 2.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEPHMAFF_01619 1.3e-33 ywzB S Protein of unknown function (DUF1146)
MEPHMAFF_01620 4.5e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MEPHMAFF_01621 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEPHMAFF_01622 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MEPHMAFF_01623 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MEPHMAFF_01624 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEPHMAFF_01625 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MEPHMAFF_01626 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEPHMAFF_01627 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
MEPHMAFF_01628 5e-232 pyrP F Permease
MEPHMAFF_01629 6.3e-129 yibF S overlaps another CDS with the same product name
MEPHMAFF_01630 9.9e-192 yibE S overlaps another CDS with the same product name
MEPHMAFF_01631 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEPHMAFF_01632 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MEPHMAFF_01633 9.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MEPHMAFF_01634 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MEPHMAFF_01635 5.7e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEPHMAFF_01636 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MEPHMAFF_01637 6e-108 tdk 2.7.1.21 F thymidine kinase
MEPHMAFF_01638 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
MEPHMAFF_01639 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MEPHMAFF_01640 2.7e-223 arcD U Amino acid permease
MEPHMAFF_01641 2e-261 E Arginine ornithine antiporter
MEPHMAFF_01642 4.7e-79 argR K Regulates arginine biosynthesis genes
MEPHMAFF_01643 4.1e-239 arcA 3.5.3.6 E Arginine
MEPHMAFF_01644 3.9e-187 ampC V Beta-lactamase
MEPHMAFF_01645 1.9e-32
MEPHMAFF_01646 0.0 M domain protein
MEPHMAFF_01647 2.4e-92
MEPHMAFF_01649 1.9e-159 yjcE P Sodium proton antiporter
MEPHMAFF_01650 6.7e-73 yjcE P Sodium proton antiporter
MEPHMAFF_01652 5.2e-56
MEPHMAFF_01654 1.7e-84
MEPHMAFF_01655 0.0 copA 3.6.3.54 P P-type ATPase
MEPHMAFF_01656 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MEPHMAFF_01657 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MEPHMAFF_01658 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MEPHMAFF_01659 3.3e-161 EG EamA-like transporter family
MEPHMAFF_01660 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
MEPHMAFF_01661 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MEPHMAFF_01662 8.1e-154 KT YcbB domain
MEPHMAFF_01663 1.8e-300 xylB 2.7.1.17 G Belongs to the FGGY kinase family
MEPHMAFF_01664 5.6e-164 xylR GK ROK family
MEPHMAFF_01665 1.3e-28
MEPHMAFF_01666 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
MEPHMAFF_01667 9e-94 lacA 2.3.1.79 S Transferase hexapeptide repeat
MEPHMAFF_01668 4.4e-155 glcU U sugar transport
MEPHMAFF_01669 6.8e-273 yclK 2.7.13.3 T Histidine kinase
MEPHMAFF_01670 1.5e-132 K response regulator
MEPHMAFF_01672 2.8e-79 lytE M Lysin motif
MEPHMAFF_01673 2e-149 XK27_02985 S Cof-like hydrolase
MEPHMAFF_01674 2.3e-81 K Transcriptional regulator
MEPHMAFF_01675 0.0 oatA I Acyltransferase
MEPHMAFF_01676 8.7e-53
MEPHMAFF_01677 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEPHMAFF_01678 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MEPHMAFF_01679 2e-126 ybbR S YbbR-like protein
MEPHMAFF_01680 1.9e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEPHMAFF_01681 6.1e-244 fucP G Major Facilitator Superfamily
MEPHMAFF_01682 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MEPHMAFF_01683 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEPHMAFF_01684 3.6e-168 murB 1.3.1.98 M Cell wall formation
MEPHMAFF_01685 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
MEPHMAFF_01686 4.4e-76 S PAS domain
MEPHMAFF_01687 2.6e-86 K Acetyltransferase (GNAT) domain
MEPHMAFF_01688 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MEPHMAFF_01689 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MEPHMAFF_01690 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEPHMAFF_01691 6.3e-105 yxjI
MEPHMAFF_01692 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MEPHMAFF_01693 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MEPHMAFF_01694 6.8e-147 est 3.1.1.1 S Serine aminopeptidase, S33
MEPHMAFF_01695 1.8e-34 secG U Preprotein translocase
MEPHMAFF_01696 2.6e-291 clcA P chloride
MEPHMAFF_01697 7.1e-248 yifK E Amino acid permease
MEPHMAFF_01698 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEPHMAFF_01699 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEPHMAFF_01700 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MEPHMAFF_01701 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEPHMAFF_01703 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEPHMAFF_01704 8.8e-15
MEPHMAFF_01706 4e-170 whiA K May be required for sporulation
MEPHMAFF_01707 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MEPHMAFF_01708 3.2e-161 rapZ S Displays ATPase and GTPase activities
MEPHMAFF_01709 5.4e-245 steT E amino acid
MEPHMAFF_01710 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEPHMAFF_01711 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEPHMAFF_01712 1.3e-12
MEPHMAFF_01713 2.3e-116 yfbR S HD containing hydrolase-like enzyme
MEPHMAFF_01714 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MEPHMAFF_01715 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
MEPHMAFF_01716 3.5e-103 aatB ET PFAM extracellular solute-binding protein, family 3
MEPHMAFF_01717 5.9e-32 aatB ET PFAM extracellular solute-binding protein, family 3
MEPHMAFF_01718 3.8e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MEPHMAFF_01719 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEPHMAFF_01720 3.5e-163 lutA C Cysteine-rich domain
MEPHMAFF_01721 9.8e-288 lutB C 4Fe-4S dicluster domain
MEPHMAFF_01722 3.9e-136 yrjD S LUD domain
MEPHMAFF_01723 2.3e-237 L Transposase
MEPHMAFF_01724 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MEPHMAFF_01725 6.9e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MEPHMAFF_01726 1.3e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEPHMAFF_01727 8.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MEPHMAFF_01728 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MEPHMAFF_01729 3.1e-32 KT PspC domain protein
MEPHMAFF_01730 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEPHMAFF_01731 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEPHMAFF_01732 4.2e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MEPHMAFF_01733 1.3e-114 comFC S Competence protein
MEPHMAFF_01734 1.4e-256 comFA L Helicase C-terminal domain protein
MEPHMAFF_01735 2.9e-111 yvyE 3.4.13.9 S YigZ family
MEPHMAFF_01736 4.8e-236 EGP Major facilitator Superfamily
MEPHMAFF_01737 7.4e-68 rmaI K Transcriptional regulator
MEPHMAFF_01738 1.2e-39
MEPHMAFF_01739 0.0 ydaO E amino acid
MEPHMAFF_01740 3.6e-304 ybeC E amino acid
MEPHMAFF_01741 8.2e-82 S YbaK proline--tRNA ligase associated domain protein
MEPHMAFF_01742 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEPHMAFF_01743 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEPHMAFF_01745 1.4e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MEPHMAFF_01746 0.0 uup S ABC transporter, ATP-binding protein
MEPHMAFF_01747 8e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEPHMAFF_01748 2.5e-225 mtnE 2.6.1.83 E Aminotransferase
MEPHMAFF_01749 2.3e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MEPHMAFF_01750 1.4e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEPHMAFF_01751 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MEPHMAFF_01752 3.6e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEPHMAFF_01753 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEPHMAFF_01754 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MEPHMAFF_01755 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MEPHMAFF_01756 4.2e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MEPHMAFF_01757 5.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MEPHMAFF_01758 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MEPHMAFF_01759 3.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MEPHMAFF_01760 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
MEPHMAFF_01761 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEPHMAFF_01762 5.9e-58 yabA L Involved in initiation control of chromosome replication
MEPHMAFF_01763 8.2e-185 holB 2.7.7.7 L DNA polymerase III
MEPHMAFF_01764 7.6e-52 yaaQ S Cyclic-di-AMP receptor
MEPHMAFF_01765 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEPHMAFF_01766 9.7e-39 S Protein of unknown function (DUF2508)
MEPHMAFF_01767 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEPHMAFF_01768 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MEPHMAFF_01769 6.2e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEPHMAFF_01770 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEPHMAFF_01771 3.4e-35 nrdH O Glutaredoxin
MEPHMAFF_01772 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEPHMAFF_01773 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEPHMAFF_01774 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MEPHMAFF_01775 6.4e-126 S Putative adhesin
MEPHMAFF_01776 1.3e-81 XK27_06920 S Protein of unknown function (DUF1700)
MEPHMAFF_01777 4e-56 K transcriptional regulator PadR family
MEPHMAFF_01778 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEPHMAFF_01780 1.5e-48
MEPHMAFF_01781 2e-169 L Transposase and inactivated derivatives IS30 family
MEPHMAFF_01782 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEPHMAFF_01783 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MEPHMAFF_01784 1.5e-172 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MEPHMAFF_01785 1.9e-26 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MEPHMAFF_01786 5.5e-220 M Glycosyl transferase family group 2
MEPHMAFF_01788 1.3e-226 aadAT EK Aminotransferase, class I
MEPHMAFF_01789 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEPHMAFF_01790 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEPHMAFF_01791 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
MEPHMAFF_01792 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MEPHMAFF_01793 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MEPHMAFF_01794 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEPHMAFF_01795 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MEPHMAFF_01796 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEPHMAFF_01797 1.7e-207 yacL S domain protein
MEPHMAFF_01798 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEPHMAFF_01799 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MEPHMAFF_01800 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
MEPHMAFF_01801 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MEPHMAFF_01802 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
MEPHMAFF_01803 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MEPHMAFF_01804 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEPHMAFF_01805 2.4e-119 tcyB E ABC transporter
MEPHMAFF_01806 4.2e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MEPHMAFF_01807 3.1e-169 I alpha/beta hydrolase fold
MEPHMAFF_01808 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEPHMAFF_01809 0.0 S Bacterial membrane protein, YfhO
MEPHMAFF_01810 4.5e-185 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MEPHMAFF_01811 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MEPHMAFF_01813 1.9e-85 ydcK S Belongs to the SprT family
MEPHMAFF_01814 0.0 yhgF K Tex-like protein N-terminal domain protein
MEPHMAFF_01815 5.1e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MEPHMAFF_01816 1.7e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEPHMAFF_01817 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
MEPHMAFF_01818 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MEPHMAFF_01819 9.5e-300 aspT P Predicted Permease Membrane Region
MEPHMAFF_01820 2.4e-251 EGP Major facilitator Superfamily
MEPHMAFF_01821 5.5e-110
MEPHMAFF_01824 1.4e-158 yjjH S Calcineurin-like phosphoesterase
MEPHMAFF_01825 5e-263 dtpT U amino acid peptide transporter
MEPHMAFF_01826 3.7e-19
MEPHMAFF_01828 3.7e-91 yqiG C Oxidoreductase
MEPHMAFF_01829 7.8e-20 yqiG C Oxidoreductase
MEPHMAFF_01830 1.1e-50 yqiG C Oxidoreductase
MEPHMAFF_01831 8.5e-54 S macrophage migration inhibitory factor
MEPHMAFF_01832 2.4e-65 K HxlR-like helix-turn-helix
MEPHMAFF_01833 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MEPHMAFF_01835 7.6e-181 L Transposase IS66 family
MEPHMAFF_01837 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
MEPHMAFF_01838 5.4e-281 L Transposase IS66 family
MEPHMAFF_01840 5.5e-280 O Arylsulfotransferase (ASST)
MEPHMAFF_01841 8.1e-190 L PFAM Integrase catalytic region
MEPHMAFF_01842 2.2e-49 ebh D nuclear chromosome segregation
MEPHMAFF_01844 2.4e-120 UW LPXTG-motif cell wall anchor domain protein
MEPHMAFF_01845 4.4e-140 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MEPHMAFF_01846 3.4e-47
MEPHMAFF_01847 3e-13
MEPHMAFF_01848 6.9e-10
MEPHMAFF_01849 2.6e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MEPHMAFF_01850 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEPHMAFF_01851 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MEPHMAFF_01852 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEPHMAFF_01853 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MEPHMAFF_01854 3.8e-257 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEPHMAFF_01855 9.8e-67 yabR J RNA binding
MEPHMAFF_01856 3.3e-56 divIC D Septum formation initiator
MEPHMAFF_01857 8.1e-39 yabO J S4 domain protein
MEPHMAFF_01858 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEPHMAFF_01859 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEPHMAFF_01860 4e-113 S (CBS) domain
MEPHMAFF_01861 3.1e-147 tesE Q hydratase
MEPHMAFF_01862 4.7e-243 codA 3.5.4.1 F cytosine deaminase
MEPHMAFF_01863 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
MEPHMAFF_01864 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
MEPHMAFF_01865 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEPHMAFF_01866 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MEPHMAFF_01868 4.2e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEPHMAFF_01869 3.7e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
MEPHMAFF_01870 4.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEPHMAFF_01871 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MEPHMAFF_01872 6.5e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
MEPHMAFF_01873 1e-141 sprD D Domain of Unknown Function (DUF1542)
MEPHMAFF_01874 3.1e-126 L PFAM Integrase catalytic region
MEPHMAFF_01875 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MEPHMAFF_01876 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEPHMAFF_01877 9.8e-158 htpX O Belongs to the peptidase M48B family
MEPHMAFF_01878 7e-93 lemA S LemA family
MEPHMAFF_01879 5.7e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MEPHMAFF_01880 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
MEPHMAFF_01881 1.1e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MEPHMAFF_01882 3.1e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEPHMAFF_01883 3.3e-234 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MEPHMAFF_01884 1.1e-124 srtA 3.4.22.70 M sortase family
MEPHMAFF_01885 1.3e-165 S Alpha/beta hydrolase of unknown function (DUF915)
MEPHMAFF_01886 1.2e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEPHMAFF_01887 4.6e-41 rpmE2 J Ribosomal protein L31
MEPHMAFF_01888 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEPHMAFF_01889 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEPHMAFF_01890 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MEPHMAFF_01891 3e-66 ywiB S Domain of unknown function (DUF1934)
MEPHMAFF_01892 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
MEPHMAFF_01893 5e-270 ywfO S HD domain protein
MEPHMAFF_01894 2.5e-147 yxeH S hydrolase
MEPHMAFF_01895 2.1e-49
MEPHMAFF_01896 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEPHMAFF_01897 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MEPHMAFF_01898 2.6e-149 purR 2.4.2.7 F pur operon repressor
MEPHMAFF_01899 1.4e-118 znuB U ABC 3 transport family
MEPHMAFF_01900 1.4e-121 fhuC P ABC transporter
MEPHMAFF_01901 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
MEPHMAFF_01902 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MEPHMAFF_01903 6.8e-37 veg S Biofilm formation stimulator VEG
MEPHMAFF_01904 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEPHMAFF_01905 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MEPHMAFF_01906 1.9e-155 tatD L hydrolase, TatD family
MEPHMAFF_01907 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEPHMAFF_01908 3.6e-162 yunF F Protein of unknown function DUF72
MEPHMAFF_01910 3e-130 cobB K SIR2 family
MEPHMAFF_01911 1.6e-177
MEPHMAFF_01912 2.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MEPHMAFF_01913 1.3e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MEPHMAFF_01914 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEPHMAFF_01915 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MEPHMAFF_01916 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
MEPHMAFF_01917 0.0 helD 3.6.4.12 L DNA helicase
MEPHMAFF_01918 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEPHMAFF_01920 7.7e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MEPHMAFF_01921 1e-265 yfnA E amino acid
MEPHMAFF_01922 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MEPHMAFF_01923 5.8e-40 1.3.5.4 S FMN binding
MEPHMAFF_01924 6e-219 norA EGP Major facilitator Superfamily
MEPHMAFF_01925 5.2e-237 L Transposase
MEPHMAFF_01926 6.2e-190 L PFAM Integrase catalytic region
MEPHMAFF_01927 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MEPHMAFF_01928 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
MEPHMAFF_01929 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEPHMAFF_01930 3.1e-103 metI P ABC transporter permease
MEPHMAFF_01931 7e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MEPHMAFF_01932 1.2e-252 clcA P chloride
MEPHMAFF_01933 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MEPHMAFF_01934 4.5e-104 proW P ABC transporter, permease protein
MEPHMAFF_01935 1e-139 proV E ABC transporter, ATP-binding protein
MEPHMAFF_01936 6.3e-109 proWZ P ABC transporter permease
MEPHMAFF_01937 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
MEPHMAFF_01938 3.6e-260 S Uncharacterised protein family (UPF0236)
MEPHMAFF_01939 9e-75 K Transcriptional regulator
MEPHMAFF_01940 4.8e-154 1.6.5.2 GM NAD(P)H-binding
MEPHMAFF_01942 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
MEPHMAFF_01943 0.0 cadA P P-type ATPase
MEPHMAFF_01944 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MEPHMAFF_01945 2.3e-189 L PFAM Integrase catalytic region
MEPHMAFF_01946 2.1e-126
MEPHMAFF_01947 3.3e-55 S Sugar efflux transporter for intercellular exchange
MEPHMAFF_01948 2.9e-106 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_01949 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MEPHMAFF_01951 0.0 L Helicase C-terminal domain protein
MEPHMAFF_01952 1.2e-75 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
MEPHMAFF_01953 2.6e-177 S Aldo keto reductase
MEPHMAFF_01955 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEPHMAFF_01956 4.5e-62 psiE S Phosphate-starvation-inducible E
MEPHMAFF_01957 1e-101 ydeN S Serine hydrolase
MEPHMAFF_01959 7e-63 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEPHMAFF_01960 6.6e-108 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEPHMAFF_01961 8e-255 nhaC C Na H antiporter NhaC
MEPHMAFF_01962 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
MEPHMAFF_01963 4.8e-114 ywnB S NAD(P)H-binding
MEPHMAFF_01964 2.9e-37
MEPHMAFF_01965 9.3e-130 IQ Dehydrogenase reductase
MEPHMAFF_01966 5.8e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
MEPHMAFF_01967 2.7e-68 L Belongs to the 'phage' integrase family
MEPHMAFF_01968 4.3e-126 L PFAM Integrase catalytic region
MEPHMAFF_01969 1e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MEPHMAFF_01970 5.5e-45 yitW S Pfam:DUF59
MEPHMAFF_01971 1.6e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MEPHMAFF_01972 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_01973 5.6e-119 L Belongs to the 'phage' integrase family
MEPHMAFF_01974 1.9e-10
MEPHMAFF_01979 1.9e-101 M Glycosyl hydrolases family 25
MEPHMAFF_01980 1.6e-27 cotH M CotH kinase protein
MEPHMAFF_01981 7.6e-71
MEPHMAFF_01982 4.2e-190 ganB 3.2.1.89 G arabinogalactan
MEPHMAFF_01983 3.2e-124 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MEPHMAFF_01984 3.4e-126 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
MEPHMAFF_01990 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEPHMAFF_01991 9.7e-173
MEPHMAFF_01992 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEPHMAFF_01993 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
MEPHMAFF_01994 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MEPHMAFF_01995 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MEPHMAFF_01996 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MEPHMAFF_01997 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MEPHMAFF_01998 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEPHMAFF_01999 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEPHMAFF_02000 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEPHMAFF_02001 9.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MEPHMAFF_02002 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MEPHMAFF_02003 4.7e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEPHMAFF_02004 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MEPHMAFF_02005 3.7e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
MEPHMAFF_02006 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MEPHMAFF_02007 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MEPHMAFF_02008 4.9e-177 K AI-2E family transporter
MEPHMAFF_02009 1.1e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MEPHMAFF_02010 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MEPHMAFF_02011 9.6e-115 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
MEPHMAFF_02012 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEPHMAFF_02013 1.7e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MEPHMAFF_02014 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MEPHMAFF_02015 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEPHMAFF_02016 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MEPHMAFF_02017 7.4e-134 K LysR substrate binding domain
MEPHMAFF_02018 5.9e-48 L PFAM transposase IS200-family protein
MEPHMAFF_02019 5.6e-261 S Uncharacterised protein family (UPF0236)
MEPHMAFF_02020 1.6e-52 azlD S branched-chain amino acid
MEPHMAFF_02021 3.7e-136 azlC E AzlC protein
MEPHMAFF_02022 6.5e-199 hpk31 2.7.13.3 T Histidine kinase
MEPHMAFF_02023 1.2e-123 K response regulator
MEPHMAFF_02024 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEPHMAFF_02025 9.5e-172 deoR K sugar-binding domain protein
MEPHMAFF_02026 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MEPHMAFF_02027 2.7e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
MEPHMAFF_02028 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MEPHMAFF_02029 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MEPHMAFF_02030 7.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
MEPHMAFF_02031 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEPHMAFF_02032 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
MEPHMAFF_02033 1.7e-154 spo0J K Belongs to the ParB family
MEPHMAFF_02034 3.9e-139 soj D Sporulation initiation inhibitor
MEPHMAFF_02035 3.7e-150 noc K Belongs to the ParB family
MEPHMAFF_02036 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MEPHMAFF_02037 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
MEPHMAFF_02038 5.6e-169 rihC 3.2.2.1 F Nucleoside
MEPHMAFF_02039 2.3e-218 nupG F Nucleoside transporter
MEPHMAFF_02040 7.2e-221 cycA E Amino acid permease
MEPHMAFF_02042 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEPHMAFF_02043 1.2e-264 glnP P ABC transporter
MEPHMAFF_02044 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEPHMAFF_02045 2.5e-158 L hmm pf00665
MEPHMAFF_02046 4.4e-100 L Helix-turn-helix domain
MEPHMAFF_02048 5.9e-191 V Beta-lactamase
MEPHMAFF_02049 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MEPHMAFF_02050 5e-122 yhiD S MgtC family
MEPHMAFF_02051 6.4e-39 S GyrI-like small molecule binding domain
MEPHMAFF_02052 2.7e-70 S GyrI-like small molecule binding domain
MEPHMAFF_02054 6.1e-117 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MEPHMAFF_02055 7.1e-50 azlD E Branched-chain amino acid transport
MEPHMAFF_02056 3.4e-33 azlC E azaleucine resistance protein AzlC
MEPHMAFF_02057 2.1e-76 azlC E azaleucine resistance protein AzlC
MEPHMAFF_02058 2e-169 L Transposase and inactivated derivatives IS30 family
MEPHMAFF_02059 7.3e-60 K Aminotransferase class I and II
MEPHMAFF_02060 2e-152 K Aminotransferase class I and II
MEPHMAFF_02061 4.5e-275 S amidohydrolase
MEPHMAFF_02063 1.8e-161 S reductase
MEPHMAFF_02064 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
MEPHMAFF_02065 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MEPHMAFF_02066 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
MEPHMAFF_02067 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEPHMAFF_02068 0.0 asnB 6.3.5.4 E Asparagine synthase
MEPHMAFF_02069 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MEPHMAFF_02070 8.7e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MEPHMAFF_02071 9.7e-130 jag S R3H domain protein
MEPHMAFF_02072 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEPHMAFF_02073 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MEPHMAFF_02074 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MEPHMAFF_02076 8.5e-64 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
MEPHMAFF_02077 4.2e-103 mrr L restriction endonuclease
MEPHMAFF_02078 0.0 L Type III restriction enzyme, res subunit
MEPHMAFF_02079 4.6e-79 L Integrase
MEPHMAFF_02080 1.6e-07 S Short C-terminal domain
MEPHMAFF_02081 4.8e-36 lytE M LysM domain protein
MEPHMAFF_02082 6.2e-190 L PFAM Integrase catalytic region
MEPHMAFF_02083 1.3e-89 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MEPHMAFF_02086 2.1e-97 L Belongs to the 'phage' integrase family
MEPHMAFF_02087 4.8e-227 L transposase, IS605 OrfB family
MEPHMAFF_02088 4.2e-80 tlpA2 L Transposase IS200 like
MEPHMAFF_02089 1.2e-21 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MEPHMAFF_02092 3.4e-171 L Integrase core domain
MEPHMAFF_02093 1.9e-46 L Transposase
MEPHMAFF_02095 4.9e-22
MEPHMAFF_02096 7.3e-21 relB L Addiction module antitoxin, RelB DinJ family
MEPHMAFF_02105 1.5e-06 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEPHMAFF_02108 2.2e-22
MEPHMAFF_02115 7.8e-14 ard S Antirestriction protein (ArdA)
MEPHMAFF_02119 2.1e-38
MEPHMAFF_02121 2.7e-89 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MEPHMAFF_02122 4.7e-13 S Replication initiator protein A (RepA) N-terminus
MEPHMAFF_02125 6.6e-09 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEPHMAFF_02126 1.3e-103 tra L Transposase and inactivated derivatives, IS30 family
MEPHMAFF_02127 4.6e-137 L PFAM Integrase catalytic region
MEPHMAFF_02128 6.6e-20 L Integrase
MEPHMAFF_02129 4.8e-59 L Integrase
MEPHMAFF_02131 1.8e-46 S Acetyltransferase (GNAT) domain
MEPHMAFF_02132 1.2e-80 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEPHMAFF_02133 1.4e-34 L Transposase
MEPHMAFF_02134 1.2e-211 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MEPHMAFF_02135 5.3e-136 L PFAM Integrase catalytic region
MEPHMAFF_02136 2.6e-103 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
MEPHMAFF_02137 7.6e-08 S response to antibiotic
MEPHMAFF_02138 1.8e-167 L Transposase and inactivated derivatives IS30 family
MEPHMAFF_02139 2.9e-174 adhP 1.1.1.1 C alcohol dehydrogenase
MEPHMAFF_02140 6.7e-139 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEPHMAFF_02141 4.2e-224 glpT G Major Facilitator Superfamily
MEPHMAFF_02142 9.1e-28 scrR3 K Transcriptional regulator, LacI family
MEPHMAFF_02143 8.4e-70 L Helix-turn-helix domain
MEPHMAFF_02144 3.1e-137 L hmm pf00665
MEPHMAFF_02145 3.1e-59
MEPHMAFF_02146 1.9e-204
MEPHMAFF_02148 3e-44
MEPHMAFF_02149 1.7e-33 S RelB antitoxin
MEPHMAFF_02150 3.1e-104 L Integrase
MEPHMAFF_02151 2.2e-87 D AAA domain
MEPHMAFF_02152 4.6e-42
MEPHMAFF_02155 3.8e-236 EGP Major facilitator Superfamily
MEPHMAFF_02156 5e-17 yrkL S Flavodoxin-like fold
MEPHMAFF_02157 9.2e-178 L PFAM Integrase catalytic region
MEPHMAFF_02158 1.1e-310 uup S ABC transporter, ATP-binding protein
MEPHMAFF_02159 9.3e-69 L Helix-turn-helix domain
MEPHMAFF_02160 9e-137 L hmm pf00665
MEPHMAFF_02161 2.4e-31 S CAAX protease self-immunity
MEPHMAFF_02163 0.0 tetP J Elongation Factor G, domain II
MEPHMAFF_02164 6.6e-51 S Conjugative transposon protein TcpC
MEPHMAFF_02165 2.3e-53 S Bacterial protein of unknown function (DUF961)
MEPHMAFF_02166 8.8e-23
MEPHMAFF_02167 1.7e-08
MEPHMAFF_02169 9.2e-174
MEPHMAFF_02170 3.8e-15

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)