ORF_ID e_value Gene_name EC_number CAZy COGs Description
GDBHMKAN_00001 1.4e-78 S DNA primase
GDBHMKAN_00002 4.6e-45 L Primase C terminal 1 (PriCT-1)
GDBHMKAN_00007 3.2e-117
GDBHMKAN_00008 7.3e-105
GDBHMKAN_00009 5.6e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
GDBHMKAN_00010 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GDBHMKAN_00011 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GDBHMKAN_00012 7.2e-77 infB UW LPXTG-motif cell wall anchor domain protein
GDBHMKAN_00013 1.4e-51
GDBHMKAN_00014 1.8e-82 L Transposase, IS116 IS110 IS902 family
GDBHMKAN_00015 1.1e-18 dprA LU DNA protecting protein DprA
GDBHMKAN_00016 1.3e-158 ccpA K catabolite control protein A
GDBHMKAN_00017 3.1e-27 cspC K Cold shock protein
GDBHMKAN_00018 6.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
GDBHMKAN_00019 4.5e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
GDBHMKAN_00020 1.6e-22
GDBHMKAN_00021 1.2e-58 3.6.1.27 I phosphatase
GDBHMKAN_00022 2.8e-26
GDBHMKAN_00023 3.6e-66 I alpha/beta hydrolase fold
GDBHMKAN_00024 1.3e-38 azlD S branched-chain amino acid
GDBHMKAN_00025 1.9e-104 azlC E AzlC protein
GDBHMKAN_00026 2e-17
GDBHMKAN_00027 8.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
GDBHMKAN_00028 4.3e-149 EGP Sugar (and other) transporter
GDBHMKAN_00029 7.8e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
GDBHMKAN_00030 6.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GDBHMKAN_00031 8.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GDBHMKAN_00032 1.1e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GDBHMKAN_00033 2.7e-56 P Plays a role in the regulation of phosphate uptake
GDBHMKAN_00034 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
GDBHMKAN_00035 1.1e-79 S VIT family
GDBHMKAN_00036 9.4e-84 S membrane
GDBHMKAN_00037 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
GDBHMKAN_00038 5.2e-65 hly S protein, hemolysin III
GDBHMKAN_00039 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
GDBHMKAN_00040 1.7e-74 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GDBHMKAN_00043 3e-14
GDBHMKAN_00044 2.7e-77 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
GDBHMKAN_00045 3e-08 XK27_10540 S ParE toxin of type II toxin-antitoxin system, parDE
GDBHMKAN_00046 4.5e-09 D Antitoxin Phd_YefM, type II toxin-antitoxin system
GDBHMKAN_00047 0.0 clpE O Belongs to the ClpA ClpB family
GDBHMKAN_00048 1e-12 L Transposase
GDBHMKAN_00049 3.4e-225 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GDBHMKAN_00050 9.5e-95 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
GDBHMKAN_00051 1.7e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GDBHMKAN_00052 1.5e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GDBHMKAN_00053 2.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GDBHMKAN_00054 2.5e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
GDBHMKAN_00055 1.2e-117 comEC S Competence protein ComEC
GDBHMKAN_00056 3.9e-169 clcA P chloride
GDBHMKAN_00057 2.8e-19 secG U Preprotein translocase
GDBHMKAN_00058 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GDBHMKAN_00059 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GDBHMKAN_00060 3.1e-42 yxjI
GDBHMKAN_00061 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
GDBHMKAN_00062 6.8e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GDBHMKAN_00063 1.3e-142 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GDBHMKAN_00064 2.5e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
GDBHMKAN_00065 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
GDBHMKAN_00066 1.2e-115 murB 1.3.1.98 M Cell wall formation
GDBHMKAN_00067 9.5e-25
GDBHMKAN_00068 5e-23 ykzG S Belongs to the UPF0356 family
GDBHMKAN_00069 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GDBHMKAN_00070 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GDBHMKAN_00071 7.8e-198 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GDBHMKAN_00072 7.8e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GDBHMKAN_00073 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GDBHMKAN_00074 6.1e-19 S Tetratricopeptide repeat
GDBHMKAN_00075 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GDBHMKAN_00076 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GDBHMKAN_00077 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GDBHMKAN_00078 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
GDBHMKAN_00079 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GDBHMKAN_00080 1.2e-197 yfnA E amino acid
GDBHMKAN_00081 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
GDBHMKAN_00082 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GDBHMKAN_00083 1e-32 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GDBHMKAN_00084 3.5e-35 FbpA K Fibronectin-binding protein
GDBHMKAN_00085 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GDBHMKAN_00086 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GDBHMKAN_00087 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GDBHMKAN_00088 8.7e-144 iunH2 3.2.2.1 F nucleoside hydrolase
GDBHMKAN_00089 6.4e-12
GDBHMKAN_00090 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GDBHMKAN_00091 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
GDBHMKAN_00092 3.9e-127 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GDBHMKAN_00093 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GDBHMKAN_00094 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GDBHMKAN_00095 6.9e-43 yodB K Transcriptional regulator, HxlR family
GDBHMKAN_00096 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
GDBHMKAN_00097 1e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GDBHMKAN_00101 2.8e-279 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GDBHMKAN_00102 2.4e-44 S Repeat protein
GDBHMKAN_00103 8.9e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
GDBHMKAN_00104 9.5e-48 M Exporter of polyketide antibiotics
GDBHMKAN_00105 2e-93 M Exporter of polyketide antibiotics
GDBHMKAN_00106 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GDBHMKAN_00107 3.4e-78 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
GDBHMKAN_00108 1.2e-21 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
GDBHMKAN_00109 1.4e-90 L Probable transposase
GDBHMKAN_00110 2.1e-243 E Amino acid permease
GDBHMKAN_00111 3.8e-08 E Amino acid permease
GDBHMKAN_00112 2.3e-181 pepS E Thermophilic metalloprotease (M29)
GDBHMKAN_00113 4.6e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GDBHMKAN_00114 1.8e-70 K Sugar-specific transcriptional regulator TrmB
GDBHMKAN_00115 3e-38 S Sulfite exporter TauE/SafE
GDBHMKAN_00116 2.1e-153 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GDBHMKAN_00118 1.5e-67 S Polysaccharide pyruvyl transferase
GDBHMKAN_00119 5.5e-115 cps2J S Polysaccharide biosynthesis protein
GDBHMKAN_00121 1.7e-73 epsB M biosynthesis protein
GDBHMKAN_00122 6.5e-81 ywqD 2.7.10.1 D Capsular exopolysaccharide family
GDBHMKAN_00123 2.1e-111 ywqE 3.1.3.48 GM PHP domain protein
GDBHMKAN_00124 2.4e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GDBHMKAN_00125 1e-90 rfbP M Bacterial sugar transferase
GDBHMKAN_00126 5.7e-76 M Core-2/I-Branching enzyme
GDBHMKAN_00127 4.5e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
GDBHMKAN_00128 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GDBHMKAN_00129 1.6e-98 rrmA 2.1.1.187 H Methyltransferase
GDBHMKAN_00130 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GDBHMKAN_00131 8.1e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GDBHMKAN_00132 4.2e-21 cutC P Participates in the control of copper homeostasis
GDBHMKAN_00133 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
GDBHMKAN_00134 8.3e-28 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
GDBHMKAN_00135 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GDBHMKAN_00136 5.3e-68 ybbR S YbbR-like protein
GDBHMKAN_00137 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GDBHMKAN_00138 1.3e-56 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
GDBHMKAN_00139 1.3e-68 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GDBHMKAN_00140 3.2e-108 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
GDBHMKAN_00141 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GDBHMKAN_00142 2.1e-280 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GDBHMKAN_00143 1.2e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GDBHMKAN_00144 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GDBHMKAN_00145 1.8e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GDBHMKAN_00146 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GDBHMKAN_00147 2.4e-33 S CAAX protease self-immunity
GDBHMKAN_00148 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GDBHMKAN_00149 3.5e-253 uup S ABC transporter, ATP-binding protein
GDBHMKAN_00150 1.4e-160 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GDBHMKAN_00151 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
GDBHMKAN_00152 4.1e-69 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
GDBHMKAN_00153 2.3e-139 ansA 3.5.1.1 EJ Asparaginase
GDBHMKAN_00154 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
GDBHMKAN_00155 3.2e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GDBHMKAN_00156 1.4e-40 yabA L Involved in initiation control of chromosome replication
GDBHMKAN_00157 1e-83 holB 2.7.7.7 L DNA polymerase III
GDBHMKAN_00158 4.7e-66 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GDBHMKAN_00159 9.2e-29 yaaL S Protein of unknown function (DUF2508)
GDBHMKAN_00160 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GDBHMKAN_00161 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GDBHMKAN_00162 5.1e-211 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GDBHMKAN_00163 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GDBHMKAN_00164 3.2e-75 rsmC 2.1.1.172 J Methyltransferase
GDBHMKAN_00165 2.7e-27 nrdH O Glutaredoxin
GDBHMKAN_00166 6.3e-45 nrdI F NrdI Flavodoxin like
GDBHMKAN_00167 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GDBHMKAN_00168 2.7e-48 S Domain of unknown function (DUF956)
GDBHMKAN_00169 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GDBHMKAN_00170 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GDBHMKAN_00171 4.9e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GDBHMKAN_00172 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
GDBHMKAN_00173 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
GDBHMKAN_00174 1.7e-259 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GDBHMKAN_00175 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GDBHMKAN_00176 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
GDBHMKAN_00177 4.8e-170 nusA K Participates in both transcription termination and antitermination
GDBHMKAN_00178 1.4e-39 ylxR K Protein of unknown function (DUF448)
GDBHMKAN_00179 6.9e-26 ylxQ J ribosomal protein
GDBHMKAN_00180 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GDBHMKAN_00181 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GDBHMKAN_00182 9.1e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GDBHMKAN_00183 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GDBHMKAN_00184 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GDBHMKAN_00185 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GDBHMKAN_00186 1.5e-274 dnaK O Heat shock 70 kDa protein
GDBHMKAN_00187 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GDBHMKAN_00188 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GDBHMKAN_00189 2.2e-204 G PTS system Galactitol-specific IIC component
GDBHMKAN_00191 1.1e-41 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
GDBHMKAN_00192 1.8e-179 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
GDBHMKAN_00193 6.9e-80
GDBHMKAN_00194 7.6e-82 yjfP S COG1073 Hydrolases of the alpha beta superfamily
GDBHMKAN_00195 5.1e-113 yitU 3.1.3.104 S hydrolase
GDBHMKAN_00196 1.5e-60 speG J Acetyltransferase (GNAT) domain
GDBHMKAN_00197 1.8e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GDBHMKAN_00198 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
GDBHMKAN_00199 6.5e-204 pipD E Dipeptidase
GDBHMKAN_00200 3.6e-43
GDBHMKAN_00201 2.6e-64 K helix_turn_helix, arabinose operon control protein
GDBHMKAN_00202 5.2e-54 S Membrane
GDBHMKAN_00203 0.0 rafA 3.2.1.22 G alpha-galactosidase
GDBHMKAN_00204 1e-58 L Helicase C-terminal domain protein
GDBHMKAN_00205 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
GDBHMKAN_00206 1.1e-148 yedE S Sulphur transport
GDBHMKAN_00207 2.7e-100 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
GDBHMKAN_00208 2.4e-176 rnfC C RnfC Barrel sandwich hybrid domain
GDBHMKAN_00209 9e-29 yitW S Iron-sulfur cluster assembly protein
GDBHMKAN_00210 1.1e-17 selA 2.9.1.1 J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
GDBHMKAN_00211 2.2e-18 thiN 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
GDBHMKAN_00212 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GDBHMKAN_00213 4.5e-53 asp S Asp23 family, cell envelope-related function
GDBHMKAN_00214 1.3e-238 yloV S DAK2 domain fusion protein YloV
GDBHMKAN_00215 4e-247 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GDBHMKAN_00216 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GDBHMKAN_00217 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GDBHMKAN_00218 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GDBHMKAN_00219 1.4e-207 smc D Required for chromosome condensation and partitioning
GDBHMKAN_00220 7.2e-146 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GDBHMKAN_00221 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GDBHMKAN_00222 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GDBHMKAN_00223 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GDBHMKAN_00224 3.8e-27 ylqC S Belongs to the UPF0109 family
GDBHMKAN_00225 2.4e-16
GDBHMKAN_00226 6.1e-103 V domain protein
GDBHMKAN_00227 1.7e-42 XK27_03960 S Protein of unknown function (DUF3013)
GDBHMKAN_00228 2.2e-117 prmA J Ribosomal protein L11 methyltransferase
GDBHMKAN_00229 4.8e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GDBHMKAN_00230 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GDBHMKAN_00231 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GDBHMKAN_00232 5.1e-57 3.1.3.18 J HAD-hyrolase-like
GDBHMKAN_00233 3.4e-42 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GDBHMKAN_00234 1.4e-127 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GDBHMKAN_00235 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GDBHMKAN_00236 3.5e-204 pyrP F Permease
GDBHMKAN_00237 7.4e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GDBHMKAN_00238 3.8e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GDBHMKAN_00239 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GDBHMKAN_00240 2e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GDBHMKAN_00241 3.7e-134 K Transcriptional regulator
GDBHMKAN_00242 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
GDBHMKAN_00243 2.6e-77 S Haloacid dehalogenase-like hydrolase
GDBHMKAN_00244 2.7e-15
GDBHMKAN_00246 4.5e-187 mtnE 2.6.1.83 E Aminotransferase
GDBHMKAN_00247 9.1e-83 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
GDBHMKAN_00248 3.4e-67 S Protein of unknown function (DUF1440)
GDBHMKAN_00249 7.7e-41 S Iron-sulfur cluster assembly protein
GDBHMKAN_00250 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GDBHMKAN_00251 1.3e-74 sdaAB 4.3.1.17 E Serine dehydratase beta chain
GDBHMKAN_00252 3.9e-207 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GDBHMKAN_00253 7.9e-155 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GDBHMKAN_00254 4.7e-65 G Xylose isomerase domain protein TIM barrel
GDBHMKAN_00255 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
GDBHMKAN_00256 6.5e-90 nanK GK ROK family
GDBHMKAN_00257 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
GDBHMKAN_00258 3.3e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GDBHMKAN_00259 1.9e-75 K Helix-turn-helix domain, rpiR family
GDBHMKAN_00260 7.2e-59 yphA GM NAD dependent epimerase/dehydratase family
GDBHMKAN_00261 7e-217 yjeM E Amino Acid
GDBHMKAN_00263 1.2e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GDBHMKAN_00264 2.2e-178 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
GDBHMKAN_00265 3.9e-48 fucU 5.1.3.29 G RbsD / FucU transport protein family
GDBHMKAN_00266 3.5e-180 xylB 2.7.1.17 GH19 EGP Major facilitator Superfamily
GDBHMKAN_00267 8.9e-132 rhaB 2.7.1.5, 2.7.1.51 G FGGY family of carbohydrate kinases, N-terminal domain
GDBHMKAN_00268 2.6e-295 fucI 5.3.1.25, 5.3.1.3 G Converts the aldose L-fucose into the corresponding ketose L-fuculose
GDBHMKAN_00269 6.6e-30 fcsR K DeoR C terminal sensor domain
GDBHMKAN_00270 2.8e-11 K DeoR C terminal sensor domain
GDBHMKAN_00271 2.5e-101 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
GDBHMKAN_00272 1.5e-07 cps2D 5.1.3.2 M RmlD substrate binding domain
GDBHMKAN_00273 2.8e-40 wecD M Acetyltransferase (GNAT) family
GDBHMKAN_00277 4.5e-252 L Transposase DDE domain group 1
GDBHMKAN_00278 8.5e-93 apt 2.4.2.7 F purine ribonucleoside salvage
GDBHMKAN_00279 3.8e-167 aadK G adenylyltransferase
GDBHMKAN_00280 6.8e-141 Q Protein of unknown function (DUF1698)
GDBHMKAN_00281 3.1e-164 L Nucleotidyltransferase domain
GDBHMKAN_00282 1.6e-32 K Cro/C1-type HTH DNA-binding domain
GDBHMKAN_00283 2.3e-295 L Recombinase
GDBHMKAN_00284 1.1e-71 S Recombinase
GDBHMKAN_00285 7.5e-83 L COG1961 Site-specific recombinases, DNA invertase Pin homologs
GDBHMKAN_00286 9.5e-53 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GDBHMKAN_00287 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
GDBHMKAN_00289 2.5e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GDBHMKAN_00290 1.3e-159 iscS 2.8.1.7 E Aminotransferase class V
GDBHMKAN_00291 3.7e-41 XK27_04120 S Putative amino acid metabolism
GDBHMKAN_00292 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GDBHMKAN_00294 4.9e-176 yjcE P Sodium proton antiporter
GDBHMKAN_00295 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GDBHMKAN_00296 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
GDBHMKAN_00297 5.6e-69 dhaL 2.7.1.121 S Dak2
GDBHMKAN_00298 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
GDBHMKAN_00299 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
GDBHMKAN_00300 1.7e-61 K Bacterial regulatory proteins, tetR family
GDBHMKAN_00301 1.9e-208 brnQ U Component of the transport system for branched-chain amino acids
GDBHMKAN_00303 1.7e-111 endA F DNA RNA non-specific endonuclease
GDBHMKAN_00304 4.1e-75 XK27_02070 S Nitroreductase family
GDBHMKAN_00305 1.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
GDBHMKAN_00306 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
GDBHMKAN_00307 4.7e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
GDBHMKAN_00308 1.2e-221 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GDBHMKAN_00309 6.9e-214 G phosphotransferase system
GDBHMKAN_00310 9.7e-91 licT K CAT RNA binding domain
GDBHMKAN_00311 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
GDBHMKAN_00312 2.7e-58 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
GDBHMKAN_00313 5.1e-77 azlC E branched-chain amino acid
GDBHMKAN_00314 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
GDBHMKAN_00315 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
GDBHMKAN_00316 1.6e-55 jag S R3H domain protein
GDBHMKAN_00317 9.1e-54 K Transcriptional regulator C-terminal region
GDBHMKAN_00318 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
GDBHMKAN_00319 1.1e-286 pepO 3.4.24.71 O Peptidase family M13
GDBHMKAN_00320 2.2e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
GDBHMKAN_00321 9.5e-08 S SdpI/YhfL protein family
GDBHMKAN_00322 6.6e-71 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
GDBHMKAN_00323 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
GDBHMKAN_00324 1.2e-41 wecD K Acetyltransferase GNAT Family
GDBHMKAN_00326 1.1e-34 tetR K transcriptional regulator
GDBHMKAN_00329 1e-09 3.1.3.48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GDBHMKAN_00332 3.1e-36 ypmB S Protein conserved in bacteria
GDBHMKAN_00333 3.1e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
GDBHMKAN_00334 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
GDBHMKAN_00335 5.1e-56 dnaD L DnaD domain protein
GDBHMKAN_00336 1.5e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GDBHMKAN_00337 2.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GDBHMKAN_00338 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GDBHMKAN_00339 6.2e-92 M transferase activity, transferring glycosyl groups
GDBHMKAN_00340 2.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
GDBHMKAN_00341 9.6e-109 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GDBHMKAN_00342 2e-66 nss M transferase activity, transferring glycosyl groups
GDBHMKAN_00343 1.4e-07 M Glycosyltransferase like family 2
GDBHMKAN_00344 7.6e-15 arbx M family 8
GDBHMKAN_00346 1.2e-55 nss M transferase activity, transferring glycosyl groups
GDBHMKAN_00347 1.6e-38 M Glycosyl transferase family 8
GDBHMKAN_00350 1.9e-42 ybl78 L DnaD domain protein
GDBHMKAN_00351 4.8e-09
GDBHMKAN_00354 3.3e-192 pepV 3.5.1.18 E dipeptidase PepV
GDBHMKAN_00355 4.1e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GDBHMKAN_00356 1.1e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GDBHMKAN_00357 1.1e-186 ytgP S Polysaccharide biosynthesis protein
GDBHMKAN_00358 2.4e-192 cycA E Amino acid permease
GDBHMKAN_00359 7.5e-225 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GDBHMKAN_00360 7e-152 V Pfam:Methyltransf_26
GDBHMKAN_00363 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GDBHMKAN_00364 1.8e-208 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GDBHMKAN_00367 5.4e-127 corA P CorA-like Mg2+ transporter protein
GDBHMKAN_00368 5.4e-201 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
GDBHMKAN_00369 1.1e-258 U COG3505 Type IV secretory pathway, VirD4 components
GDBHMKAN_00370 7.7e-80
GDBHMKAN_00371 8.3e-25 yqfZ 3.2.1.17 M hydrolase, family 25
GDBHMKAN_00372 6.2e-87 L Replication initiation factor
GDBHMKAN_00373 3.1e-29 L Single-strand binding protein family
GDBHMKAN_00374 2e-53 L Phage integrase, N-terminal SAM-like domain
GDBHMKAN_00375 5.3e-109 ymfF S Peptidase M16 inactive domain protein
GDBHMKAN_00376 2.4e-149 ymfH S Peptidase M16
GDBHMKAN_00377 2.4e-90 IQ Enoyl-(Acyl carrier protein) reductase
GDBHMKAN_00378 1.5e-63 ymfM S Helix-turn-helix domain
GDBHMKAN_00379 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GDBHMKAN_00380 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GDBHMKAN_00381 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
GDBHMKAN_00382 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GDBHMKAN_00383 2.2e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GDBHMKAN_00384 4.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GDBHMKAN_00385 1.1e-152 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GDBHMKAN_00386 1e-182 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GDBHMKAN_00387 2.3e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GDBHMKAN_00388 1.4e-12 yajC U Preprotein translocase
GDBHMKAN_00390 4.3e-61 uspA T universal stress protein
GDBHMKAN_00392 2e-208 yfnA E Amino Acid
GDBHMKAN_00393 5.1e-16
GDBHMKAN_00395 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GDBHMKAN_00396 5.9e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
GDBHMKAN_00397 2.9e-72 ecsB U ABC transporter
GDBHMKAN_00398 9.8e-95 ecsA V ABC transporter, ATP-binding protein
GDBHMKAN_00399 7e-53 hit FG histidine triad
GDBHMKAN_00401 1.5e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GDBHMKAN_00402 2.1e-126 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
GDBHMKAN_00403 2e-21 yheA S Belongs to the UPF0342 family
GDBHMKAN_00404 1.5e-284 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GDBHMKAN_00407 2.4e-47 S Short repeat of unknown function (DUF308)
GDBHMKAN_00408 4.7e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GDBHMKAN_00409 6.2e-163 oxlT P Major Facilitator Superfamily
GDBHMKAN_00410 4.5e-67 ybbL S ABC transporter
GDBHMKAN_00411 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
GDBHMKAN_00412 3e-41 ytcD K HxlR-like helix-turn-helix
GDBHMKAN_00413 8.4e-119 ytbE S reductase
GDBHMKAN_00414 2.3e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GDBHMKAN_00415 3.8e-188 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
GDBHMKAN_00416 2.1e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
GDBHMKAN_00417 0.0 S Bacterial membrane protein YfhO
GDBHMKAN_00418 5.1e-53 gtcA S Teichoic acid glycosylation protein
GDBHMKAN_00419 5.1e-54 fld C Flavodoxin
GDBHMKAN_00420 2.4e-92 yueF S AI-2E family transporter
GDBHMKAN_00421 2.6e-97 ygaC J Belongs to the UPF0374 family
GDBHMKAN_00422 6.5e-193 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GDBHMKAN_00423 3.4e-69 recX 2.4.1.337 GT4 S Regulatory protein RecX
GDBHMKAN_00424 4e-19 sigH K DNA-templated transcription, initiation
GDBHMKAN_00425 3.5e-22 S Cytochrome B5
GDBHMKAN_00426 3.6e-64 recN L May be involved in recombinational repair of damaged DNA
GDBHMKAN_00427 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GDBHMKAN_00428 2.9e-30 ynzC S UPF0291 protein
GDBHMKAN_00429 1.8e-34 ypbB 5.1.3.1 S Helix-turn-helix domain
GDBHMKAN_00430 1.5e-132 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
GDBHMKAN_00431 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GDBHMKAN_00432 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GDBHMKAN_00433 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GDBHMKAN_00434 1.4e-54
GDBHMKAN_00435 7.9e-41 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GDBHMKAN_00437 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GDBHMKAN_00438 1.8e-172 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GDBHMKAN_00439 3.1e-36 rnhA 3.1.26.4 L Ribonuclease HI
GDBHMKAN_00440 1.5e-22 S Family of unknown function (DUF5322)
GDBHMKAN_00441 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GDBHMKAN_00442 1.8e-38
GDBHMKAN_00445 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
GDBHMKAN_00446 6.6e-63 licT K transcriptional antiterminator
GDBHMKAN_00447 1.4e-28 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GDBHMKAN_00448 9.3e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
GDBHMKAN_00449 3.8e-58 pstS P Phosphate
GDBHMKAN_00450 5.4e-119 pstC P probably responsible for the translocation of the substrate across the membrane
GDBHMKAN_00451 3e-122 pstA P Phosphate transport system permease protein PstA
GDBHMKAN_00452 3.6e-39
GDBHMKAN_00458 1.9e-08 2.3.1.19 K Cro/C1-type HTH DNA-binding domain
GDBHMKAN_00461 8.8e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
GDBHMKAN_00462 2.2e-12 tetR K Transcriptional regulator C-terminal region
GDBHMKAN_00463 4.5e-151 yfeX P Peroxidase
GDBHMKAN_00464 7.8e-18 S Protein of unknown function (DUF3021)
GDBHMKAN_00465 1e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GDBHMKAN_00466 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GDBHMKAN_00467 3.7e-46 yqhY S Asp23 family, cell envelope-related function
GDBHMKAN_00468 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GDBHMKAN_00469 1.3e-41 dut S dUTPase
GDBHMKAN_00470 3.7e-90 yunF F Protein of unknown function DUF72
GDBHMKAN_00471 1.7e-156 nrnB S DHHA1 domain
GDBHMKAN_00472 4.8e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GDBHMKAN_00473 1.6e-149 nhaC C Na H antiporter NhaC
GDBHMKAN_00474 4.2e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GDBHMKAN_00475 9.7e-74 draG O ADP-ribosylglycohydrolase
GDBHMKAN_00477 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
GDBHMKAN_00478 6.9e-92 T Calcineurin-like phosphoesterase superfamily domain
GDBHMKAN_00479 4.2e-49 lytE M LysM domain protein
GDBHMKAN_00480 5.2e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
GDBHMKAN_00482 6.2e-64 srtA 3.4.22.70 M sortase family
GDBHMKAN_00483 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GDBHMKAN_00484 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GDBHMKAN_00485 1.1e-33
GDBHMKAN_00486 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GDBHMKAN_00487 1e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GDBHMKAN_00488 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GDBHMKAN_00489 3.6e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
GDBHMKAN_00490 1.1e-39 ybjQ S Belongs to the UPF0145 family
GDBHMKAN_00491 9.7e-08
GDBHMKAN_00492 3e-95 V ABC transporter, ATP-binding protein
GDBHMKAN_00493 1.1e-41 gntR1 K Transcriptional regulator, GntR family
GDBHMKAN_00494 2.4e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
GDBHMKAN_00495 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GDBHMKAN_00496 3.8e-262 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
GDBHMKAN_00497 2.2e-107 terC P Integral membrane protein TerC family
GDBHMKAN_00498 1.6e-38 K Transcriptional regulator
GDBHMKAN_00499 9.8e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
GDBHMKAN_00500 1.6e-100 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GDBHMKAN_00501 4.5e-102 tcyB E ABC transporter
GDBHMKAN_00503 3.7e-13 ponA V the current gene model (or a revised gene model) may contain a frame shift
GDBHMKAN_00504 2.3e-187 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GDBHMKAN_00505 7.8e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GDBHMKAN_00506 3.2e-51 mtlR K Mga helix-turn-helix domain
GDBHMKAN_00507 9.4e-109 L Initiator Replication protein
GDBHMKAN_00508 1.6e-36 S Replication initiator protein A (RepA) N-terminus
GDBHMKAN_00509 6.8e-169 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GDBHMKAN_00510 2e-47 pts33BCA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Pts system
GDBHMKAN_00511 2.6e-86 ykuT M mechanosensitive ion channel
GDBHMKAN_00512 2.4e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GDBHMKAN_00513 3e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GDBHMKAN_00514 1.5e-45 ykuL S CBS domain
GDBHMKAN_00515 1.3e-118 gla U Major intrinsic protein
GDBHMKAN_00517 3.3e-92 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GDBHMKAN_00518 1.7e-44
GDBHMKAN_00519 1.4e-120 ica2 GT2 M Glycosyl transferase family group 2
GDBHMKAN_00520 2.7e-158 dnaE 2.7.7.7 L DNA polymerase
GDBHMKAN_00521 4.6e-191 pepF E oligoendopeptidase F
GDBHMKAN_00523 1.7e-126 S ABC-2 family transporter protein
GDBHMKAN_00524 8.2e-111 bcrA V ABC transporter
GDBHMKAN_00525 2.4e-13
GDBHMKAN_00532 3.7e-96 yicL EG EamA-like transporter family
GDBHMKAN_00533 6e-223 pepF E Oligopeptidase F
GDBHMKAN_00534 8.6e-109 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GDBHMKAN_00535 1.7e-178 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GDBHMKAN_00536 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GDBHMKAN_00537 2.8e-27 2.7.13.3 T GHKL domain
GDBHMKAN_00538 4.3e-56 K LytTr DNA-binding domain
GDBHMKAN_00544 1.7e-71 xerD L Phage integrase, N-terminal SAM-like domain
GDBHMKAN_00545 3.8e-93 yihY S Belongs to the UPF0761 family
GDBHMKAN_00546 4.7e-12 mltD CBM50 M Lysin motif
GDBHMKAN_00547 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GDBHMKAN_00548 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
GDBHMKAN_00549 9.6e-41 wecD M Acetyltransferase (GNAT) family
GDBHMKAN_00550 5.9e-76 cps2D 5.1.3.2 M RmlD substrate binding domain
GDBHMKAN_00551 2.1e-65 H Methyltransferase domain
GDBHMKAN_00554 1e-12 L Transposase
GDBHMKAN_00555 1.3e-24 L recombinase activity
GDBHMKAN_00556 4.1e-73
GDBHMKAN_00557 2.8e-22
GDBHMKAN_00558 5e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GDBHMKAN_00559 5e-104 K response regulator
GDBHMKAN_00560 1.6e-168 T PhoQ Sensor
GDBHMKAN_00561 6.7e-146 lmrP E Major Facilitator Superfamily
GDBHMKAN_00563 5.3e-70 M Domain of unknown function (DUF4422)
GDBHMKAN_00564 1.7e-56 cps3F
GDBHMKAN_00569 1.5e-69 S RRXRR protein
GDBHMKAN_00572 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
GDBHMKAN_00573 1e-27 ysxB J Cysteine protease Prp
GDBHMKAN_00574 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GDBHMKAN_00575 3.7e-12
GDBHMKAN_00577 4.8e-72
GDBHMKAN_00578 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
GDBHMKAN_00579 7.6e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GDBHMKAN_00580 2e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
GDBHMKAN_00581 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GDBHMKAN_00582 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GDBHMKAN_00583 5.9e-111 galR K Transcriptional regulator
GDBHMKAN_00584 8.9e-289 lacS G Transporter
GDBHMKAN_00585 3e-26 1.1.1.27 C L-malate dehydrogenase activity
GDBHMKAN_00586 1.2e-24 yktA S Belongs to the UPF0223 family
GDBHMKAN_00587 6.3e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
GDBHMKAN_00588 2.9e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
GDBHMKAN_00589 9.5e-59 hsdM 2.1.1.72 V HsdM N-terminal domain
GDBHMKAN_00591 1.8e-151 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GDBHMKAN_00592 5e-51 S COG NOG19168 non supervised orthologous group
GDBHMKAN_00593 1.3e-180 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
GDBHMKAN_00594 3.8e-50 S Membrane
GDBHMKAN_00595 1.4e-75 rhaR K helix_turn_helix, arabinose operon control protein
GDBHMKAN_00596 1.5e-188 iolF EGP Major facilitator Superfamily
GDBHMKAN_00597 5.8e-216 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
GDBHMKAN_00598 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
GDBHMKAN_00599 4.8e-219 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
GDBHMKAN_00600 6.9e-110 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
GDBHMKAN_00602 1.2e-187 XK27_11280 S Psort location CytoplasmicMembrane, score
GDBHMKAN_00603 1.5e-199 L Transposase DDE domain group 1
GDBHMKAN_00604 2.7e-66
GDBHMKAN_00605 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GDBHMKAN_00606 5.6e-127
GDBHMKAN_00607 5.1e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
GDBHMKAN_00608 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
GDBHMKAN_00609 4.1e-11
GDBHMKAN_00611 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GDBHMKAN_00612 2.1e-19 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GDBHMKAN_00613 1.3e-15 ald 1.4.1.1 C Belongs to the AlaDH PNT family
GDBHMKAN_00614 1.1e-166 potE2 E amino acid
GDBHMKAN_00615 2.8e-266 fbp 3.1.3.11 G phosphatase activity
GDBHMKAN_00616 9.1e-24 L Lactococcus lactis RepB C-terminus
GDBHMKAN_00618 4e-118 S Uncharacterised protein family (UPF0236)
GDBHMKAN_00619 1.8e-116 degV S EDD domain protein, DegV family
GDBHMKAN_00620 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
GDBHMKAN_00621 5.5e-40 6.3.3.2 S ASCH
GDBHMKAN_00622 8.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GDBHMKAN_00627 1.9e-73
GDBHMKAN_00630 1.1e-202 traI 5.99.1.2 L C-terminal repeat of topoisomerase
GDBHMKAN_00632 1.2e-192 clpB O Belongs to the ClpA ClpB family
GDBHMKAN_00634 2e-69 comEB 3.5.4.12 F ComE operon protein 2
GDBHMKAN_00635 3.1e-50 comEA L Competence protein ComEA
GDBHMKAN_00636 3.4e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
GDBHMKAN_00637 3e-162 ytbD EGP Major facilitator Superfamily
GDBHMKAN_00638 6.1e-99 fabK 1.3.1.9 S Nitronate monooxygenase
GDBHMKAN_00639 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GDBHMKAN_00640 1.6e-183 cycA E Amino acid permease
GDBHMKAN_00641 2.6e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
GDBHMKAN_00642 4.2e-96 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
GDBHMKAN_00643 1.9e-181 L Transposase DDE domain group 1
GDBHMKAN_00644 2.9e-121 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GDBHMKAN_00647 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GDBHMKAN_00648 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GDBHMKAN_00649 1.8e-56 yqeY S YqeY-like protein
GDBHMKAN_00650 2.4e-31 M Glycosyltransferase like family 2
GDBHMKAN_00651 4.8e-82 yitS S EDD domain protein, DegV family
GDBHMKAN_00653 2.4e-78 repE K Primase C terminal 1 (PriCT-1)
GDBHMKAN_00654 8e-61
GDBHMKAN_00655 1.4e-40 rpmE2 J Ribosomal protein L31
GDBHMKAN_00656 4.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GDBHMKAN_00657 1.6e-201 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GDBHMKAN_00660 3.3e-289 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GDBHMKAN_00661 9.9e-42 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GDBHMKAN_00662 1.8e-32 ywiB S Domain of unknown function (DUF1934)
GDBHMKAN_00663 9.8e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
GDBHMKAN_00664 2.5e-205 ywfO S HD domain protein
GDBHMKAN_00665 1.7e-87 S hydrolase
GDBHMKAN_00666 1.2e-70 ydcZ S Putative inner membrane exporter, YdcZ
GDBHMKAN_00667 9.8e-100 D Alpha beta
GDBHMKAN_00668 1.7e-109 aatB ET ABC transporter substrate-binding protein
GDBHMKAN_00669 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GDBHMKAN_00670 1.9e-94 glnP P ABC transporter permease
GDBHMKAN_00671 1.8e-126 minD D Belongs to the ParA family
GDBHMKAN_00672 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GDBHMKAN_00673 1.5e-54 mreD M rod shape-determining protein MreD
GDBHMKAN_00674 2.1e-88 mreC M Involved in formation and maintenance of cell shape
GDBHMKAN_00675 3.6e-156 mreB D cell shape determining protein MreB
GDBHMKAN_00676 4.5e-21 K Cold shock
GDBHMKAN_00677 5.3e-79 radC L DNA repair protein
GDBHMKAN_00678 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GDBHMKAN_00679 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GDBHMKAN_00680 3.2e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GDBHMKAN_00681 2.5e-161 iscS2 2.8.1.7 E Aminotransferase class V
GDBHMKAN_00682 7.6e-120 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GDBHMKAN_00683 9.9e-36 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GDBHMKAN_00684 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
GDBHMKAN_00685 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GDBHMKAN_00686 2e-24 yueI S Protein of unknown function (DUF1694)
GDBHMKAN_00687 2.7e-185 rarA L recombination factor protein RarA
GDBHMKAN_00689 3.2e-73 usp6 T universal stress protein
GDBHMKAN_00690 3.8e-54 tag 3.2.2.20 L glycosylase
GDBHMKAN_00691 2.2e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GDBHMKAN_00692 3.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GDBHMKAN_00694 3.5e-115 sip L Belongs to the 'phage' integrase family
GDBHMKAN_00695 1.2e-09 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GDBHMKAN_00696 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GDBHMKAN_00697 6.1e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GDBHMKAN_00698 4.4e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GDBHMKAN_00699 6.6e-49 argR K Regulates arginine biosynthesis genes
GDBHMKAN_00700 3e-124 yvgN C Aldo keto reductase
GDBHMKAN_00701 2.1e-19 M domain protein
GDBHMKAN_00702 3e-35 agrA KT Response regulator of the LytR AlgR family
GDBHMKAN_00703 1e-43 2.7.13.3 T protein histidine kinase activity
GDBHMKAN_00704 3.2e-181 pbuG S permease
GDBHMKAN_00706 1.5e-72 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GDBHMKAN_00707 1.5e-41 S Phosphoesterase
GDBHMKAN_00709 3.9e-41 yjbH Q Thioredoxin
GDBHMKAN_00710 1e-46 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GDBHMKAN_00711 4.3e-15 S Protein of unknown function (DUF2929)
GDBHMKAN_00712 9e-76 L Lactococcus lactis RepB C-terminus
GDBHMKAN_00713 5.6e-57 racA K Domain of unknown function (DUF1836)
GDBHMKAN_00714 3.6e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GDBHMKAN_00715 5.5e-243 lysP E amino acid
GDBHMKAN_00716 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
GDBHMKAN_00717 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GDBHMKAN_00718 1.2e-13 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GDBHMKAN_00719 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
GDBHMKAN_00720 1.1e-81 lysR5 K LysR substrate binding domain
GDBHMKAN_00721 1.7e-119 yxaA S membrane transporter protein
GDBHMKAN_00722 2.6e-32 ywjH S Protein of unknown function (DUF1634)
GDBHMKAN_00723 7e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GDBHMKAN_00724 5.1e-225 pipD E Dipeptidase
GDBHMKAN_00725 1.8e-21 K helix_turn_helix multiple antibiotic resistance protein
GDBHMKAN_00726 1.5e-165 EGP Major facilitator Superfamily
GDBHMKAN_00727 4.7e-81 S L,D-transpeptidase catalytic domain
GDBHMKAN_00728 1.9e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GDBHMKAN_00729 4.3e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GDBHMKAN_00730 7.2e-27 ydiI Q Thioesterase superfamily
GDBHMKAN_00731 5.6e-57 yfeJ 6.3.5.2 F glutamine amidotransferase
GDBHMKAN_00732 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
GDBHMKAN_00733 6.4e-114 degV S EDD domain protein, DegV family
GDBHMKAN_00734 3.4e-226 cadA P P-type ATPase
GDBHMKAN_00735 1.8e-254 E Amino acid permease
GDBHMKAN_00736 2.1e-83 S Membrane
GDBHMKAN_00737 2e-49 cps3F
GDBHMKAN_00738 3.3e-283 fruA 2.7.1.202 GT Phosphotransferase System
GDBHMKAN_00739 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GDBHMKAN_00740 9e-88 fruR K DeoR C terminal sensor domain
GDBHMKAN_00741 6.7e-219 XK27_08635 S UPF0210 protein
GDBHMKAN_00742 4.1e-27 gcvR T Belongs to the UPF0237 family
GDBHMKAN_00743 2.3e-38
GDBHMKAN_00744 1.3e-56 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
GDBHMKAN_00745 3.4e-134 S Tetratricopeptide repeat protein
GDBHMKAN_00746 1.8e-15
GDBHMKAN_00747 1.6e-112 rssA S Phospholipase, patatin family
GDBHMKAN_00748 1e-12 L Transposase
GDBHMKAN_00749 1.9e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
GDBHMKAN_00750 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GDBHMKAN_00751 3.6e-24 yozE S Belongs to the UPF0346 family
GDBHMKAN_00752 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
GDBHMKAN_00753 2e-51 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GDBHMKAN_00754 2.2e-20
GDBHMKAN_00755 2.5e-61 patA 2.6.1.1 E Aminotransferase
GDBHMKAN_00756 5.5e-29
GDBHMKAN_00757 2.5e-78 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GDBHMKAN_00758 3.5e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GDBHMKAN_00759 1e-79 yvfR V ABC transporter
GDBHMKAN_00760 4.2e-53 yvfS V ABC-2 type transporter
GDBHMKAN_00761 3.2e-57 salK 2.7.13.3 T Histidine kinase
GDBHMKAN_00762 4.4e-77 desR K helix_turn_helix, Lux Regulon
GDBHMKAN_00763 1.6e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
GDBHMKAN_00764 6.8e-104 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
GDBHMKAN_00768 2.4e-142 xerS L Phage integrase family
GDBHMKAN_00769 4.5e-71 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GDBHMKAN_00770 8.4e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GDBHMKAN_00771 3e-216 1.3.5.4 C FAD binding domain
GDBHMKAN_00772 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
GDBHMKAN_00773 1.6e-138 G Xylose isomerase-like TIM barrel
GDBHMKAN_00774 1.7e-72 K Transcriptional regulator, LysR family
GDBHMKAN_00775 6.3e-99 EGP Major Facilitator Superfamily
GDBHMKAN_00776 2.6e-129 EGP Major Facilitator Superfamily
GDBHMKAN_00777 5.4e-45 L PFAM Integrase catalytic region
GDBHMKAN_00779 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
GDBHMKAN_00780 7e-31 P Heavy-metal-associated domain
GDBHMKAN_00781 1.8e-160 L transposase, IS605 OrfB family
GDBHMKAN_00782 4.3e-58 tlpA2 L Transposase IS200 like
GDBHMKAN_00783 3e-125 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
GDBHMKAN_00784 5.4e-85 dps P Ferritin-like domain
GDBHMKAN_00785 1.1e-14 tnp L Transposase IS66 family
GDBHMKAN_00786 5.4e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
GDBHMKAN_00787 9e-102 qmcA O prohibitin homologues
GDBHMKAN_00788 2.1e-26 S protein encoded in hypervariable junctions of pilus gene clusters
GDBHMKAN_00789 0.0 O Belongs to the peptidase S8 family
GDBHMKAN_00790 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GDBHMKAN_00791 2.5e-136 pfoS S Phosphotransferase system, EIIC
GDBHMKAN_00792 3.3e-90
GDBHMKAN_00793 2.2e-27 M family 8
GDBHMKAN_00794 1.5e-38
GDBHMKAN_00795 7.3e-14 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
GDBHMKAN_00796 1.4e-49 I Alpha/beta hydrolase family
GDBHMKAN_00797 1.4e-94 S Bacterial membrane protein, YfhO
GDBHMKAN_00798 1.9e-53 XK27_01040 S Protein of unknown function (DUF1129)
GDBHMKAN_00799 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GDBHMKAN_00800 9e-24 yyzM S Bacterial protein of unknown function (DUF951)
GDBHMKAN_00801 4.1e-108 spo0J K Belongs to the ParB family
GDBHMKAN_00802 6.5e-118 soj D Sporulation initiation inhibitor
GDBHMKAN_00803 2.8e-82 noc K Belongs to the ParB family
GDBHMKAN_00804 4.7e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
GDBHMKAN_00805 4.5e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GDBHMKAN_00806 8.4e-110 3.1.4.46 C phosphodiesterase
GDBHMKAN_00807 0.0 pacL 3.6.3.8 P P-type ATPase
GDBHMKAN_00808 1.7e-184 L Probable transposase
GDBHMKAN_00809 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
GDBHMKAN_00810 3.4e-41 S Protein of unknown function (DUF1211)
GDBHMKAN_00812 3.3e-85 1.1.1.1 C Zinc-binding dehydrogenase
GDBHMKAN_00813 1.4e-31 S CHY zinc finger
GDBHMKAN_00814 8e-40 K Transcriptional regulator
GDBHMKAN_00815 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
GDBHMKAN_00816 3.3e-29 M Glycosyl transferases group 1
GDBHMKAN_00817 7.3e-18
GDBHMKAN_00818 2e-120 L Mrr N-terminal domain
GDBHMKAN_00820 6.4e-36 3.1.21.3 V Type I restriction modification DNA specificity domain
GDBHMKAN_00821 7.6e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GDBHMKAN_00822 9.8e-146 yegS 2.7.1.107 G Lipid kinase
GDBHMKAN_00823 5.6e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GDBHMKAN_00824 1.6e-234 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GDBHMKAN_00825 1.7e-37 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GDBHMKAN_00826 7.1e-161 camS S sex pheromone
GDBHMKAN_00827 2.3e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GDBHMKAN_00828 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GDBHMKAN_00829 3.5e-144 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GDBHMKAN_00830 4.3e-213 malT G Transporter, major facilitator family protein
GDBHMKAN_00831 9.4e-101 malR K Transcriptional regulator, LacI family
GDBHMKAN_00832 1e-279 kup P Transport of potassium into the cell
GDBHMKAN_00834 2e-20 S Domain of unknown function (DUF3284)
GDBHMKAN_00835 2e-159 yfmL L DEAD DEAH box helicase
GDBHMKAN_00836 1.6e-127 mocA S Oxidoreductase
GDBHMKAN_00837 3.4e-24 S Domain of unknown function (DUF4828)
GDBHMKAN_00838 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
GDBHMKAN_00839 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GDBHMKAN_00840 9.4e-195 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
GDBHMKAN_00841 4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
GDBHMKAN_00842 2.6e-163 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GDBHMKAN_00843 8.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GDBHMKAN_00844 4.7e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
GDBHMKAN_00845 7.9e-30 O ADP-ribosylglycohydrolase
GDBHMKAN_00847 2.4e-28 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GDBHMKAN_00849 3.3e-79 L Replication protein
GDBHMKAN_00850 1.1e-76 E GDSL-like Lipase/Acylhydrolase family
GDBHMKAN_00851 9.2e-56 S Protein of unknown function (DUF975)
GDBHMKAN_00852 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
GDBHMKAN_00853 4e-230 lpdA 1.8.1.4 C Dehydrogenase
GDBHMKAN_00854 2.9e-179 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GDBHMKAN_00855 2.8e-166 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
GDBHMKAN_00856 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
GDBHMKAN_00859 2.3e-34 S Protein of unknown function (DUF4256)
GDBHMKAN_00860 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
GDBHMKAN_00861 2.4e-31 metI U ABC transporter permease
GDBHMKAN_00862 6.2e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GDBHMKAN_00864 3.3e-265 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
GDBHMKAN_00865 1.3e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GDBHMKAN_00866 2.3e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
GDBHMKAN_00867 3.9e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
GDBHMKAN_00868 3e-84 drgA C nitroreductase
GDBHMKAN_00869 8.8e-135 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
GDBHMKAN_00870 9.6e-68 metI P ABC transporter permease
GDBHMKAN_00871 1.5e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GDBHMKAN_00872 7.4e-107 metQ1 P Belongs to the nlpA lipoprotein family
GDBHMKAN_00873 1e-143 2.1.1.14 E methionine synthase, vitamin-B12 independent
GDBHMKAN_00874 1.4e-45 yphJ 4.1.1.44 S decarboxylase
GDBHMKAN_00875 1.1e-55 yphH S Cupin domain
GDBHMKAN_00876 2.4e-46 C Flavodoxin
GDBHMKAN_00877 3.6e-56 S CAAX protease self-immunity
GDBHMKAN_00878 1.2e-102 pgm3 G phosphoglycerate mutase
GDBHMKAN_00879 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GDBHMKAN_00880 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GDBHMKAN_00881 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GDBHMKAN_00882 7.4e-67 M ErfK YbiS YcfS YnhG
GDBHMKAN_00883 1e-107 XK27_08845 S ABC transporter, ATP-binding protein
GDBHMKAN_00884 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
GDBHMKAN_00885 7.8e-132 ABC-SBP S ABC transporter
GDBHMKAN_00886 1.1e-158 potD P ABC transporter
GDBHMKAN_00887 1.3e-103 potC U Binding-protein-dependent transport system inner membrane component
GDBHMKAN_00888 9.5e-120 potB P ABC transporter permease
GDBHMKAN_00889 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GDBHMKAN_00890 7.4e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GDBHMKAN_00891 1.6e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
GDBHMKAN_00892 1.5e-235 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GDBHMKAN_00893 3.9e-13 S Enterocin A Immunity
GDBHMKAN_00894 2.2e-16 pspC KT PspC domain
GDBHMKAN_00895 7e-200 L transposition, DNA-mediated
GDBHMKAN_00896 9.4e-94 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
GDBHMKAN_00897 2.4e-16 S Putative adhesin
GDBHMKAN_00898 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
GDBHMKAN_00899 8.1e-38 K transcriptional regulator PadR family
GDBHMKAN_00900 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
GDBHMKAN_00901 4.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
GDBHMKAN_00902 2.4e-164 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GDBHMKAN_00903 1.1e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GDBHMKAN_00904 3.5e-70 mltD CBM50 M NlpC P60 family protein
GDBHMKAN_00905 1.8e-52 manO S Domain of unknown function (DUF956)
GDBHMKAN_00906 2.1e-147 manN G system, mannose fructose sorbose family IID component
GDBHMKAN_00907 8e-119 manY G PTS system sorbose-specific iic component
GDBHMKAN_00908 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
GDBHMKAN_00909 4.1e-80 rbsB G sugar-binding domain protein
GDBHMKAN_00910 5.1e-99 baeS T Histidine kinase
GDBHMKAN_00911 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
GDBHMKAN_00912 1.8e-120 G Bacterial extracellular solute-binding protein
GDBHMKAN_00913 9.1e-71 S Protein of unknown function (DUF554)
GDBHMKAN_00914 1e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GDBHMKAN_00915 1.9e-32 merR K MerR HTH family regulatory protein
GDBHMKAN_00916 2.7e-197 lmrB EGP Major facilitator Superfamily
GDBHMKAN_00917 7e-34 S Domain of unknown function (DUF4811)
GDBHMKAN_00918 4.3e-41 S CAAX protease self-immunity
GDBHMKAN_00919 1.3e-60 yceE S haloacid dehalogenase-like hydrolase
GDBHMKAN_00920 7.6e-74 glcR K DeoR C terminal sensor domain
GDBHMKAN_00921 1.7e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GDBHMKAN_00922 1.3e-183 lmrB EGP Major facilitator Superfamily
GDBHMKAN_00923 2.1e-54 bioY S BioY family
GDBHMKAN_00924 1.4e-94 S Predicted membrane protein (DUF2207)
GDBHMKAN_00925 1.4e-19
GDBHMKAN_00926 4.4e-37 M Glycosyltransferase group 2 family protein
GDBHMKAN_00927 7.4e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
GDBHMKAN_00928 2.8e-58 ktrA P TrkA-N domain
GDBHMKAN_00929 1.2e-114 ntpJ P Potassium uptake protein
GDBHMKAN_00930 1.6e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
GDBHMKAN_00931 1e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
GDBHMKAN_00932 3.5e-216 scrB 3.2.1.26 GH32 G invertase
GDBHMKAN_00933 1.7e-147 scrR K helix_turn _helix lactose operon repressor
GDBHMKAN_00934 9.4e-16 lutA C Cysteine-rich domain
GDBHMKAN_00935 1.1e-244 lutB C 4Fe-4S dicluster domain
GDBHMKAN_00936 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GDBHMKAN_00937 3e-14 S Acyltransferase family
GDBHMKAN_00938 2.2e-66 sip L Belongs to the 'phage' integrase family
GDBHMKAN_00941 2e-08 K transcriptional
GDBHMKAN_00944 2.8e-09 S Protein of unknown function (DUF805)
GDBHMKAN_00946 3e-89 S Acyltransferase family
GDBHMKAN_00947 7.3e-94 C Luciferase-like monooxygenase
GDBHMKAN_00948 1.3e-24 1.5.1.38 S FMN reductase
GDBHMKAN_00949 4.3e-26 1.5.1.38 S NADPH-dependent FMN reductase
GDBHMKAN_00950 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
GDBHMKAN_00951 3.9e-76 L haloacid dehalogenase-like hydrolase
GDBHMKAN_00952 3.1e-61 EG EamA-like transporter family
GDBHMKAN_00953 1.2e-117 K AI-2E family transporter
GDBHMKAN_00954 2.4e-172 malY 4.4.1.8 E Aminotransferase, class I
GDBHMKAN_00955 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GDBHMKAN_00957 2.5e-269 aha1 P COG COG0474 Cation transport ATPase
GDBHMKAN_00958 4.1e-296 ydaO E amino acid
GDBHMKAN_00959 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
GDBHMKAN_00960 5.4e-128 comFA L Helicase C-terminal domain protein
GDBHMKAN_00961 1.2e-46 comFC S Competence protein
GDBHMKAN_00962 1.5e-13
GDBHMKAN_00964 3.2e-135 S D5 N terminal like
GDBHMKAN_00965 3.3e-45 L Bifunctional DNA primase/polymerase, N-terminal
GDBHMKAN_00972 1e-07 K Helix-turn-helix XRE-family like proteins
GDBHMKAN_00973 5e-256 V Type II restriction enzyme, methylase subunits
GDBHMKAN_00974 1.2e-225 E ABC transporter, substratebinding protein
GDBHMKAN_00975 8.1e-116 sufC O FeS assembly ATPase SufC
GDBHMKAN_00976 2.1e-145 sufD O FeS assembly protein SufD
GDBHMKAN_00977 1.1e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GDBHMKAN_00978 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
GDBHMKAN_00979 4.2e-240 sufB O assembly protein SufB
GDBHMKAN_00980 1.1e-55 repB L Initiator Replication protein
GDBHMKAN_00981 2.6e-17 pre D Plasmid recombination enzyme
GDBHMKAN_00982 4.6e-72 catB 2.3.1.28 V This enzyme is an effector of chloramphenicol resistance in bacteria
GDBHMKAN_00983 4.1e-41 L Replication initiation factor
GDBHMKAN_00984 4.1e-240 tetL EGP Major Facilitator Superfamily
GDBHMKAN_00985 0.0 tetP J Elongation factor G, domain IV
GDBHMKAN_00986 1.6e-54 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GDBHMKAN_00987 9.3e-37 yncA 2.3.1.79 S Maltose acetyltransferase
GDBHMKAN_00988 3.4e-205 yflS P Sodium:sulfate symporter transmembrane region
GDBHMKAN_00989 1.4e-198 frdC 1.3.5.4 C FAD binding domain
GDBHMKAN_00990 1.9e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GDBHMKAN_00991 5.7e-14 ybaN S Protein of unknown function (DUF454)
GDBHMKAN_00992 2.1e-21 XK27_09445 S Domain of unknown function (DUF1827)
GDBHMKAN_00993 1.7e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
GDBHMKAN_00994 3e-311 rafA 3.2.1.22 G alpha-galactosidase
GDBHMKAN_00996 1.2e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
GDBHMKAN_00997 1.2e-27 K helix_turn_helix, mercury resistance
GDBHMKAN_00998 1.9e-88 S NADPH-dependent FMN reductase
GDBHMKAN_00999 4.7e-103 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GDBHMKAN_01000 1.5e-55 S ECF transporter, substrate-specific component
GDBHMKAN_01001 2.1e-103 znuB U ABC 3 transport family
GDBHMKAN_01002 1e-98 fhuC P ABC transporter
GDBHMKAN_01003 2.7e-104 psaA P Belongs to the bacterial solute-binding protein 9 family
GDBHMKAN_01004 3.7e-113 lacI3 K helix_turn _helix lactose operon repressor
GDBHMKAN_01005 1.2e-230 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
GDBHMKAN_01006 7.5e-39 2.7.1.191 G PTS system fructose IIA component
GDBHMKAN_01007 3.2e-123 G PTS system mannose/fructose/sorbose family IID component
GDBHMKAN_01008 4.4e-101 G PTS system sorbose-specific iic component
GDBHMKAN_01009 4.5e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
GDBHMKAN_01010 8.7e-81 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
GDBHMKAN_01011 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GDBHMKAN_01012 4.3e-184 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
GDBHMKAN_01014 2.9e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
GDBHMKAN_01015 2.2e-196 1.3.5.4 C FMN_bind
GDBHMKAN_01016 2.2e-56 3.1.3.48 K Transcriptional regulator
GDBHMKAN_01017 1.4e-160 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
GDBHMKAN_01018 7e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
GDBHMKAN_01019 4.4e-75 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
GDBHMKAN_01020 2.4e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
GDBHMKAN_01021 1e-99 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GDBHMKAN_01022 9.5e-82 S Belongs to the UPF0246 family
GDBHMKAN_01023 7.9e-12 S CAAX protease self-immunity
GDBHMKAN_01024 1.2e-59 ykhA 3.1.2.20 I Thioesterase superfamily
GDBHMKAN_01025 3.9e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GDBHMKAN_01027 2.8e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GDBHMKAN_01028 1.2e-63 C FMN binding
GDBHMKAN_01029 6.7e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GDBHMKAN_01030 1.7e-54 rplI J Binds to the 23S rRNA
GDBHMKAN_01031 6.7e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GDBHMKAN_01032 1.4e-06
GDBHMKAN_01038 5.1e-08
GDBHMKAN_01045 3.4e-92 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
GDBHMKAN_01046 3.4e-89 patB 4.4.1.8 E Aminotransferase, class I
GDBHMKAN_01047 2.5e-113 K response regulator
GDBHMKAN_01048 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
GDBHMKAN_01049 5.5e-89 lacX 5.1.3.3 G Aldose 1-epimerase
GDBHMKAN_01050 1e-146 G Transporter, major facilitator family protein
GDBHMKAN_01051 2.6e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GDBHMKAN_01052 9.5e-246 yhcA V ABC transporter, ATP-binding protein
GDBHMKAN_01053 5.8e-35 K Bacterial regulatory proteins, tetR family
GDBHMKAN_01054 9.9e-223 lmrA V ABC transporter, ATP-binding protein
GDBHMKAN_01055 3.9e-254 yfiC V ABC transporter
GDBHMKAN_01057 3.2e-45 yjcF K protein acetylation
GDBHMKAN_01058 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
GDBHMKAN_01059 8.7e-72 lemA S LemA family
GDBHMKAN_01060 1.3e-114 htpX O Belongs to the peptidase M48B family
GDBHMKAN_01062 2.2e-270 helD 3.6.4.12 L DNA helicase
GDBHMKAN_01063 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GDBHMKAN_01064 8.8e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
GDBHMKAN_01065 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
GDBHMKAN_01066 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
GDBHMKAN_01067 2e-104 ybhR V ABC transporter
GDBHMKAN_01068 2.3e-31 K Transcriptional regulator
GDBHMKAN_01069 1.6e-42 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
GDBHMKAN_01070 4.7e-148 mepA V MATE efflux family protein
GDBHMKAN_01071 1.6e-152 lsa S ABC transporter
GDBHMKAN_01072 1.8e-80 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GDBHMKAN_01073 5.7e-108 puuD S peptidase C26
GDBHMKAN_01074 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
GDBHMKAN_01075 2.3e-109 2.1.1.72, 3.1.21.3 V N-6 DNA Methylase
GDBHMKAN_01076 1.5e-43 S zinc-ribbon domain
GDBHMKAN_01077 3.3e-311 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GDBHMKAN_01078 9.5e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GDBHMKAN_01079 8.1e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GDBHMKAN_01080 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
GDBHMKAN_01081 5.4e-157 XK27_09615 S reductase
GDBHMKAN_01082 1.2e-39 2.7.7.65 T phosphorelay sensor kinase activity
GDBHMKAN_01083 1.2e-148 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
GDBHMKAN_01084 1.2e-53 cps3I G Acyltransferase family
GDBHMKAN_01085 3.6e-14
GDBHMKAN_01086 1.4e-127 S Bacterial membrane protein YfhO
GDBHMKAN_01087 3.9e-163 XK27_08315 M Sulfatase
GDBHMKAN_01088 2.8e-125 rapZ S Displays ATPase and GTPase activities
GDBHMKAN_01089 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GDBHMKAN_01090 1.8e-149 whiA K May be required for sporulation
GDBHMKAN_01091 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GDBHMKAN_01093 2.9e-137 cggR K Putative sugar-binding domain
GDBHMKAN_01094 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GDBHMKAN_01095 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GDBHMKAN_01096 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GDBHMKAN_01097 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GDBHMKAN_01098 2.7e-54 sip L Belongs to the 'phage' integrase family
GDBHMKAN_01099 8.9e-73 yjjH S Calcineurin-like phosphoesterase
GDBHMKAN_01100 1.8e-95 EG EamA-like transporter family
GDBHMKAN_01101 6.7e-85 natB CP ABC-type Na efflux pump, permease component
GDBHMKAN_01102 8.1e-112 natA S Domain of unknown function (DUF4162)
GDBHMKAN_01103 3.7e-23 K Acetyltransferase (GNAT) domain
GDBHMKAN_01105 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GDBHMKAN_01106 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GDBHMKAN_01107 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
GDBHMKAN_01108 5.3e-18
GDBHMKAN_01111 2.7e-94 pstS P T5orf172
GDBHMKAN_01112 4.8e-258 yeeB L DEAD-like helicases superfamily
GDBHMKAN_01113 6.9e-249 yeeA V Type II restriction enzyme, methylase subunits
GDBHMKAN_01114 1.5e-59 yeeA V Type II restriction enzyme, methylase subunits
GDBHMKAN_01115 4.3e-113 xerD D recombinase XerD
GDBHMKAN_01116 1.1e-124 cvfB S S1 domain
GDBHMKAN_01117 2.4e-51 yeaL S Protein of unknown function (DUF441)
GDBHMKAN_01118 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GDBHMKAN_01119 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GDBHMKAN_01120 3.2e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GDBHMKAN_01121 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GDBHMKAN_01122 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GDBHMKAN_01123 1.9e-216 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GDBHMKAN_01124 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GDBHMKAN_01125 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
GDBHMKAN_01126 4.5e-179 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
GDBHMKAN_01127 6.9e-37
GDBHMKAN_01128 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
GDBHMKAN_01129 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GDBHMKAN_01130 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GDBHMKAN_01131 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GDBHMKAN_01132 1.7e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GDBHMKAN_01134 3.1e-111 K response regulator
GDBHMKAN_01135 1.7e-167 arlS 2.7.13.3 T Histidine kinase
GDBHMKAN_01136 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
GDBHMKAN_01137 6.7e-301 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GDBHMKAN_01138 7.5e-178 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
GDBHMKAN_01139 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GDBHMKAN_01140 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GDBHMKAN_01141 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GDBHMKAN_01142 6.7e-72 ywlG S Belongs to the UPF0340 family
GDBHMKAN_01143 1.7e-128 C Oxidoreductase
GDBHMKAN_01144 2.4e-178 L transposase, IS605 OrfB family
GDBHMKAN_01145 1.5e-69 tlpA2 L Transposase IS200 like
GDBHMKAN_01146 1.6e-174 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
GDBHMKAN_01147 8.9e-44 S Domain of unknown function (DUF3841)
GDBHMKAN_01148 4.9e-56 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
GDBHMKAN_01149 1.5e-103 S Domain of unknown function (DUF4343)
GDBHMKAN_01150 0.0 L helicase activity
GDBHMKAN_01151 1.1e-210 K DNA binding
GDBHMKAN_01152 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
GDBHMKAN_01153 3.3e-222 mod 2.1.1.72, 3.1.21.5 L DNA methylase
GDBHMKAN_01154 3.5e-76 hisS 6.1.1.21 J histidyl-tRNA synthetase
GDBHMKAN_01155 4.3e-82 thrE S Putative threonine/serine exporter
GDBHMKAN_01156 6.3e-49 S Threonine/Serine exporter, ThrE
GDBHMKAN_01157 1.2e-120 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GDBHMKAN_01158 4.2e-86 S Sucrose-6F-phosphate phosphohydrolase
GDBHMKAN_01159 1.9e-34 trxA O Belongs to the thioredoxin family
GDBHMKAN_01160 9.4e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GDBHMKAN_01161 1.3e-20 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GDBHMKAN_01162 3.3e-65 degV S Uncharacterised protein, DegV family COG1307
GDBHMKAN_01164 4.3e-54 queT S QueT transporter
GDBHMKAN_01165 3.9e-34 XK27_01315 S Protein of unknown function (DUF2829)
GDBHMKAN_01166 1.2e-100 IQ Enoyl-(Acyl carrier protein) reductase
GDBHMKAN_01167 1e-111 argE 3.5.1.18 E Peptidase dimerisation domain
GDBHMKAN_01168 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GDBHMKAN_01169 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GDBHMKAN_01170 5e-87 S Alpha beta hydrolase
GDBHMKAN_01171 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GDBHMKAN_01172 3.6e-140 V MatE
GDBHMKAN_01173 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
GDBHMKAN_01174 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GDBHMKAN_01175 4.3e-97 V ABC transporter
GDBHMKAN_01176 9.6e-132 bacI V MacB-like periplasmic core domain
GDBHMKAN_01177 9e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GDBHMKAN_01178 1.7e-26
GDBHMKAN_01179 2.1e-180 yhdP S Transporter associated domain
GDBHMKAN_01180 6e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
GDBHMKAN_01181 0.0 L Helicase C-terminal domain protein
GDBHMKAN_01182 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GDBHMKAN_01183 4.3e-13 S Thioredoxin
GDBHMKAN_01185 5.7e-07 L Integrase core domain
GDBHMKAN_01186 3.1e-134 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
GDBHMKAN_01187 3.4e-60 hchA S intracellular protease amidase
GDBHMKAN_01188 5e-116 KT Putative sugar diacid recognition
GDBHMKAN_01189 1.8e-181 EG GntP family permease
GDBHMKAN_01190 6.7e-151 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GDBHMKAN_01191 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GDBHMKAN_01192 1.3e-20 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GDBHMKAN_01193 9.5e-251 ctpA 3.6.3.54 P P-type ATPase
GDBHMKAN_01194 2.4e-144 C Aldo/keto reductase family
GDBHMKAN_01195 5e-66 pgm3 G phosphoglycerate mutase family
GDBHMKAN_01196 5.1e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
GDBHMKAN_01197 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GDBHMKAN_01198 1.2e-218 yifK E Amino acid permease
GDBHMKAN_01199 3.1e-202 oppA E ABC transporter, substratebinding protein
GDBHMKAN_01200 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
GDBHMKAN_01201 3.7e-169 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
GDBHMKAN_01202 1.3e-180 oppD P Belongs to the ABC transporter superfamily
GDBHMKAN_01203 1.4e-154 oppF P Belongs to the ABC transporter superfamily
GDBHMKAN_01204 6.9e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
GDBHMKAN_01205 5.4e-208 mmuP E amino acid
GDBHMKAN_01206 1.2e-59 S Conjugative transposon protein TcpC
GDBHMKAN_01207 2.2e-190 yddH M NlpC p60 family protein
GDBHMKAN_01208 1.7e-142 S the current gene model (or a revised gene model) may contain a frame shift
GDBHMKAN_01209 2e-32 K Transcriptional regulator, HxlR family
GDBHMKAN_01210 8.6e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GDBHMKAN_01211 2.9e-102 ydhQ K UbiC transcription regulator-associated domain protein
GDBHMKAN_01212 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GDBHMKAN_01213 2.4e-82 pncA Q isochorismatase
GDBHMKAN_01214 4.6e-63 3.1.3.73 G phosphoglycerate mutase
GDBHMKAN_01215 9.5e-259 treB G phosphotransferase system
GDBHMKAN_01216 5.7e-84 treR K UTRA
GDBHMKAN_01217 8.3e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
GDBHMKAN_01218 1.9e-167 mdtG EGP Major facilitator Superfamily
GDBHMKAN_01221 1.4e-192 XK27_08315 M Sulfatase
GDBHMKAN_01222 6e-58 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GDBHMKAN_01223 4.3e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GDBHMKAN_01224 8.8e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
GDBHMKAN_01225 3.4e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GDBHMKAN_01226 8.3e-178 thrC 4.2.3.1 E Threonine synthase
GDBHMKAN_01227 9.7e-75 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GDBHMKAN_01228 1.4e-61 S Psort location CytoplasmicMembrane, score
GDBHMKAN_01229 3.7e-87 waaB GT4 M Glycosyl transferases group 1
GDBHMKAN_01230 6.4e-48 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GDBHMKAN_01231 7.6e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GDBHMKAN_01232 5e-133 coaA 2.7.1.33 F Pantothenic acid kinase
GDBHMKAN_01233 2.2e-44 E GDSL-like Lipase/Acylhydrolase
GDBHMKAN_01234 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GDBHMKAN_01235 5.6e-190 glnPH2 P ABC transporter permease
GDBHMKAN_01236 3.6e-213 yjeM E Amino Acid
GDBHMKAN_01237 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
GDBHMKAN_01238 2.3e-138 tetA EGP Major facilitator Superfamily
GDBHMKAN_01240 6.8e-69 rny D Peptidase family M23
GDBHMKAN_01241 1.8e-19 D nuclear chromosome segregation
GDBHMKAN_01242 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GDBHMKAN_01243 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GDBHMKAN_01244 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
GDBHMKAN_01245 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
GDBHMKAN_01246 4.7e-158 glk 2.7.1.2 G Glucokinase
GDBHMKAN_01247 1.4e-45 yqhL P Rhodanese-like protein
GDBHMKAN_01248 2.8e-16 WQ51_02665 S Protein of unknown function (DUF3042)
GDBHMKAN_01249 5.4e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GDBHMKAN_01250 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
GDBHMKAN_01251 1.3e-45 glnR K Transcriptional regulator
GDBHMKAN_01252 2e-247 glnA 6.3.1.2 E glutamine synthetase
GDBHMKAN_01253 2.1e-182 glnP P ABC transporter
GDBHMKAN_01254 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GDBHMKAN_01255 1.5e-31
GDBHMKAN_01256 2e-111 ampC V Beta-lactamase
GDBHMKAN_01257 3.5e-110 cobQ S glutamine amidotransferase
GDBHMKAN_01258 1e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
GDBHMKAN_01259 6.8e-86 tdk 2.7.1.21 F thymidine kinase
GDBHMKAN_01260 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GDBHMKAN_01261 3.4e-88 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GDBHMKAN_01262 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GDBHMKAN_01263 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GDBHMKAN_01264 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
GDBHMKAN_01265 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GDBHMKAN_01266 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GDBHMKAN_01267 4.1e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GDBHMKAN_01268 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GDBHMKAN_01269 5.1e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GDBHMKAN_01270 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GDBHMKAN_01271 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GDBHMKAN_01272 6e-161 purD 6.3.4.13 F Belongs to the GARS family
GDBHMKAN_01273 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GDBHMKAN_01274 1.2e-74 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GDBHMKAN_01275 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GDBHMKAN_01276 5.5e-227 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GDBHMKAN_01277 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GDBHMKAN_01278 1.2e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GDBHMKAN_01279 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GDBHMKAN_01280 2.9e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GDBHMKAN_01281 1.8e-131 ylbL T Belongs to the peptidase S16 family
GDBHMKAN_01282 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GDBHMKAN_01283 1e-72 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
GDBHMKAN_01284 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
GDBHMKAN_01285 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GDBHMKAN_01286 3e-101 ftsW D Belongs to the SEDS family
GDBHMKAN_01287 3.3e-148 manN G system, mannose fructose sorbose family IID component
GDBHMKAN_01288 7e-115 manY G PTS system
GDBHMKAN_01289 3.5e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
GDBHMKAN_01290 9.7e-184 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GDBHMKAN_01292 1.2e-103 pfoS S Phosphotransferase system, EIIC
GDBHMKAN_01293 2.9e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GDBHMKAN_01294 2.9e-149 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
GDBHMKAN_01295 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GDBHMKAN_01296 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
GDBHMKAN_01297 3e-155 amtB P ammonium transporter
GDBHMKAN_01298 9e-116 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GDBHMKAN_01299 6.6e-46 argR K Regulates arginine biosynthesis genes
GDBHMKAN_01300 1.7e-138 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
GDBHMKAN_01301 8e-90 S Alpha/beta hydrolase of unknown function (DUF915)
GDBHMKAN_01302 1.2e-22 veg S Biofilm formation stimulator VEG
GDBHMKAN_01303 7e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GDBHMKAN_01304 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GDBHMKAN_01305 9.2e-104 tatD L hydrolase, TatD family
GDBHMKAN_01306 3.2e-74 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GDBHMKAN_01307 6.5e-126 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GDBHMKAN_01308 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GDBHMKAN_01309 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
GDBHMKAN_01310 1.8e-30
GDBHMKAN_01311 1.2e-245 yjbQ P TrkA C-terminal domain protein
GDBHMKAN_01312 0.0 helD 3.6.4.12 L DNA helicase
GDBHMKAN_01313 5.2e-67 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GDBHMKAN_01314 3.4e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
GDBHMKAN_01315 7.7e-101 hrtB V ABC transporter permease
GDBHMKAN_01316 1e-34 ygfC K Bacterial regulatory proteins, tetR family
GDBHMKAN_01317 1.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GDBHMKAN_01318 9.5e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
GDBHMKAN_01319 2.1e-36 M LysM domain protein
GDBHMKAN_01320 3.7e-114 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GDBHMKAN_01321 7e-94 sbcC L Putative exonuclease SbcCD, C subunit
GDBHMKAN_01322 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
GDBHMKAN_01323 7.2e-53 perR P Belongs to the Fur family
GDBHMKAN_01324 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GDBHMKAN_01325 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GDBHMKAN_01326 3.2e-86 S (CBS) domain
GDBHMKAN_01327 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GDBHMKAN_01328 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GDBHMKAN_01329 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GDBHMKAN_01330 4.7e-139 yabM S Polysaccharide biosynthesis protein
GDBHMKAN_01331 3.6e-31 yabO J S4 domain protein
GDBHMKAN_01332 2.3e-18 divIC D Septum formation initiator
GDBHMKAN_01333 1.1e-40 yabR J RNA binding
GDBHMKAN_01334 7.2e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GDBHMKAN_01335 1.9e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GDBHMKAN_01336 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GDBHMKAN_01337 2e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GDBHMKAN_01338 3.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GDBHMKAN_01339 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GDBHMKAN_01340 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GDBHMKAN_01341 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GDBHMKAN_01342 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GDBHMKAN_01343 1.6e-55 ctsR K Belongs to the CtsR family
GDBHMKAN_01345 7.3e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GDBHMKAN_01346 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GDBHMKAN_01347 6.3e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GDBHMKAN_01348 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GDBHMKAN_01349 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GDBHMKAN_01359 2.2e-64 tal 2.2.1.2 G Transaldolase/Fructose-6-phosphate aldolase
GDBHMKAN_01360 3.1e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
GDBHMKAN_01361 2.7e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
GDBHMKAN_01362 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
GDBHMKAN_01363 4.5e-43 gutM K Glucitol operon activator protein (GutM)
GDBHMKAN_01364 1.5e-104 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
GDBHMKAN_01365 1.4e-61 IQ NAD dependent epimerase/dehydratase family
GDBHMKAN_01366 4.8e-115 S N-acetylmuramoyl-L-alanine amidase activity
GDBHMKAN_01367 2.7e-21 S Bacteriophage holin of superfamily 6 (Holin_LLH)
GDBHMKAN_01369 2.1e-15 S by MetaGeneAnnotator
GDBHMKAN_01374 7.1e-12 N Bacterial Ig-like domain 2
GDBHMKAN_01375 2.4e-27 S Calcineurin-like phosphoesterase
GDBHMKAN_01377 3.5e-100 M Prophage endopeptidase tail
GDBHMKAN_01378 7.7e-274 rny D peptidase
GDBHMKAN_01379 2e-141 S Phage tail protein
GDBHMKAN_01380 0.0 M Phage tail tape measure protein TP901
GDBHMKAN_01382 8.2e-54 S Phage tail assembly chaperone proteins, TAC
GDBHMKAN_01383 6.1e-123 S Phage tail tube protein
GDBHMKAN_01384 5.4e-65 S Protein of unknown function (DUF806)
GDBHMKAN_01385 1.9e-65 S Bacteriophage HK97-gp10, putative tail-component
GDBHMKAN_01386 4.2e-59 S Phage head-tail joining protein
GDBHMKAN_01387 4.8e-22 S Phage gp6-like head-tail connector protein
GDBHMKAN_01388 4.4e-222 S Phage capsid family
GDBHMKAN_01389 4.2e-119 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
GDBHMKAN_01390 6.7e-207 S Phage portal protein
GDBHMKAN_01392 0.0 S Phage Terminase
GDBHMKAN_01393 4.3e-83 L Phage terminase, small subunit
GDBHMKAN_01394 8.9e-90 L HNH nucleases
GDBHMKAN_01397 6.3e-17 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
GDBHMKAN_01398 1.4e-08 T SpoVT / AbrB like domain
GDBHMKAN_01399 1.4e-32 arpU S Phage transcriptional regulator, ArpU family
GDBHMKAN_01403 1.2e-49 S VRR_NUC
GDBHMKAN_01404 3e-229 S Virulence-associated protein E
GDBHMKAN_01405 2.8e-140 S Bifunctional DNA primase/polymerase, N-terminal
GDBHMKAN_01406 8.1e-85
GDBHMKAN_01407 5.6e-117 L AAA domain
GDBHMKAN_01408 5.4e-240 res L Helicase C-terminal domain protein
GDBHMKAN_01409 2e-77 S Siphovirus Gp157
GDBHMKAN_01412 1.4e-14 K Cro/C1-type HTH DNA-binding domain
GDBHMKAN_01413 5.8e-30 S Uncharacterized protein conserved in bacteria (DUF2188)
GDBHMKAN_01414 2.3e-18
GDBHMKAN_01417 1.6e-140 K Phage regulatory protein
GDBHMKAN_01418 1.7e-10 K Helix-turn-helix XRE-family like proteins
GDBHMKAN_01419 2.9e-23 3.4.21.88 K Helix-turn-helix domain
GDBHMKAN_01420 1.1e-15 S Pfam:DUF955
GDBHMKAN_01422 9.6e-28 S Short C-terminal domain
GDBHMKAN_01423 8.9e-19 L nuclease
GDBHMKAN_01424 7.3e-13
GDBHMKAN_01427 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
GDBHMKAN_01428 2.2e-07 S Protein of unknown function (DUF3397)
GDBHMKAN_01429 4.4e-63 mraZ K Belongs to the MraZ family
GDBHMKAN_01430 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GDBHMKAN_01431 2.5e-11 ftsL D cell division protein FtsL
GDBHMKAN_01432 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
GDBHMKAN_01433 1.9e-135 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GDBHMKAN_01434 1.5e-186 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GDBHMKAN_01435 1.4e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GDBHMKAN_01436 1.6e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GDBHMKAN_01437 1.6e-191 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GDBHMKAN_01438 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GDBHMKAN_01439 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GDBHMKAN_01440 3e-19 yggT S YGGT family
GDBHMKAN_01441 1.2e-82 ylmH S S4 domain protein
GDBHMKAN_01442 3.9e-62 divIVA D DivIVA domain protein
GDBHMKAN_01443 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GDBHMKAN_01444 3e-69 ybhL S Belongs to the BI1 family
GDBHMKAN_01445 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
GDBHMKAN_01446 3.8e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GDBHMKAN_01447 1.9e-237 sftA D Belongs to the FtsK SpoIIIE SftA family
GDBHMKAN_01448 5.6e-121 sip L Belongs to the 'phage' integrase family
GDBHMKAN_01449 2.3e-11 xre K sequence-specific DNA binding
GDBHMKAN_01450 1.7e-09 S Helix-turn-helix domain
GDBHMKAN_01451 7.5e-43 S Phage regulatory protein Rha (Phage_pRha)
GDBHMKAN_01459 1e-12 L Transposase
GDBHMKAN_01460 5.9e-80 ylbE GM NAD dependent epimerase dehydratase family protein
GDBHMKAN_01461 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GDBHMKAN_01462 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GDBHMKAN_01463 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GDBHMKAN_01464 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GDBHMKAN_01465 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GDBHMKAN_01466 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GDBHMKAN_01467 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
GDBHMKAN_01468 4.1e-08 KT PspC domain protein
GDBHMKAN_01469 1e-84 phoR 2.7.13.3 T Histidine kinase
GDBHMKAN_01470 3.5e-86 K response regulator
GDBHMKAN_01471 4.5e-67 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
GDBHMKAN_01472 1.1e-163 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GDBHMKAN_01473 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GDBHMKAN_01474 9.1e-95 yeaN P Major Facilitator Superfamily
GDBHMKAN_01475 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GDBHMKAN_01476 9.7e-118 sip L Belongs to the 'phage' integrase family
GDBHMKAN_01483 5.8e-79 copY K Penicillinase repressor
GDBHMKAN_01484 0.0 3.6.3.4 P haloacid dehalogenase-like hydrolase
GDBHMKAN_01485 2.4e-40 S membrane protein (DUF2078)
GDBHMKAN_01486 4.8e-16 3.2.1.23 S Domain of unknown function DUF302
GDBHMKAN_01487 1.5e-33 3.2.1.23 S Domain of unknown function DUF302
GDBHMKAN_01488 5e-117 K response regulator
GDBHMKAN_01489 6.2e-164 baeS 2.7.13.3 T Histidine kinase
GDBHMKAN_01490 2.4e-47 baeS 2.7.13.3 T Histidine kinase
GDBHMKAN_01491 5.9e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GDBHMKAN_01492 1.4e-67 spx4 1.20.4.1 P ArsC family
GDBHMKAN_01493 6e-34 L Helix-turn-helix domain
GDBHMKAN_01496 3.5e-98 cadD P Cadmium resistance transporter
GDBHMKAN_01499 3e-271 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GDBHMKAN_01500 4.9e-179 proV E ABC transporter, ATP-binding protein
GDBHMKAN_01501 6.8e-73 gshR 1.8.1.7 C Glutathione reductase
GDBHMKAN_01503 2.4e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
GDBHMKAN_01504 7.6e-210 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
GDBHMKAN_01505 2.8e-34 K GNAT family
GDBHMKAN_01506 1.7e-40
GDBHMKAN_01508 1.6e-159 mgtE P Acts as a magnesium transporter
GDBHMKAN_01509 5.4e-92 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
GDBHMKAN_01510 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GDBHMKAN_01511 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
GDBHMKAN_01512 8.1e-256 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
GDBHMKAN_01513 3.1e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
GDBHMKAN_01514 1.7e-193 pbuX F xanthine permease
GDBHMKAN_01515 3.3e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GDBHMKAN_01516 6.3e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
GDBHMKAN_01517 3.2e-64 S ECF transporter, substrate-specific component
GDBHMKAN_01518 3.9e-128 mleP S Sodium Bile acid symporter family
GDBHMKAN_01519 7e-247 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
GDBHMKAN_01520 6.2e-72 mleR K LysR family
GDBHMKAN_01521 3.1e-56 K transcriptional
GDBHMKAN_01522 2.6e-41 K Bacterial regulatory proteins, tetR family
GDBHMKAN_01523 6.1e-60 T Belongs to the universal stress protein A family
GDBHMKAN_01524 1.2e-44 K Copper transport repressor CopY TcrY
GDBHMKAN_01525 1.6e-66 3.2.1.18 GH33 M Rib/alpha-like repeat
GDBHMKAN_01526 1e-148 3.2.1.18 GH33 M Rib/alpha-like repeat
GDBHMKAN_01527 1.9e-95 ypuA S Protein of unknown function (DUF1002)
GDBHMKAN_01528 1.1e-59 dedA 3.1.3.1 S SNARE associated Golgi protein
GDBHMKAN_01529 5.2e-137 purR 2.4.2.7 F pur operon repressor
GDBHMKAN_01530 5.6e-47 EGP Transmembrane secretion effector
GDBHMKAN_01531 2.5e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GDBHMKAN_01532 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GDBHMKAN_01533 1.5e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GDBHMKAN_01535 5.8e-112 dkg S reductase
GDBHMKAN_01536 1.3e-24
GDBHMKAN_01537 1e-78 2.4.2.3 F Phosphorylase superfamily
GDBHMKAN_01538 1.4e-290 ybiT S ABC transporter, ATP-binding protein
GDBHMKAN_01539 1.5e-62 bCE_4747 S Beta-lactamase superfamily domain
GDBHMKAN_01540 1.3e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GDBHMKAN_01541 3e-124 S overlaps another CDS with the same product name
GDBHMKAN_01542 2.9e-86 S overlaps another CDS with the same product name
GDBHMKAN_01543 4.1e-15 ywzB S Protein of unknown function (DUF1146)
GDBHMKAN_01544 7.1e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GDBHMKAN_01545 3.4e-167 mbl D Cell shape determining protein MreB Mrl
GDBHMKAN_01546 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
GDBHMKAN_01547 1.3e-13 S Protein of unknown function (DUF2969)
GDBHMKAN_01548 6.1e-187 rodA D Belongs to the SEDS family
GDBHMKAN_01549 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
GDBHMKAN_01550 5.9e-10
GDBHMKAN_01551 1.2e-27 yviA S Protein of unknown function (DUF421)
GDBHMKAN_01552 7.5e-29 yviA S Protein of unknown function (DUF421)
GDBHMKAN_01553 1.8e-27 S Protein of unknown function (DUF3290)
GDBHMKAN_01554 2.3e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
GDBHMKAN_01555 4.2e-297 S membrane
GDBHMKAN_01556 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GDBHMKAN_01557 7.6e-218 recJ L Single-stranded-DNA-specific exonuclease RecJ
GDBHMKAN_01558 5.8e-101 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
GDBHMKAN_01559 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GDBHMKAN_01561 1.4e-16
GDBHMKAN_01562 6.9e-198 oatA I Acyltransferase
GDBHMKAN_01563 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GDBHMKAN_01564 1.4e-304 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GDBHMKAN_01565 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GDBHMKAN_01567 3e-105 yraQ S Predicted permease
GDBHMKAN_01568 6.9e-62 yeeE S Sulphur transport
GDBHMKAN_01569 2e-16 yeeD O Belongs to the sulfur carrier protein TusA family
GDBHMKAN_01570 2.2e-116 ynjE 2.8.1.11 P Rhodanese Homology Domain
GDBHMKAN_01572 9.5e-235 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
GDBHMKAN_01573 3.2e-26 S Psort location Cytoplasmic, score
GDBHMKAN_01574 5.8e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
GDBHMKAN_01575 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
GDBHMKAN_01576 4.7e-73 prdD S An automated process has identified a potential problem with this gene model
GDBHMKAN_01577 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
GDBHMKAN_01578 7e-144 5.1.1.4 E Proline racemase
GDBHMKAN_01579 4.4e-94 XK27_00825 S Sulfite exporter TauE/SafE
GDBHMKAN_01580 5.3e-223 ybeC E amino acid
GDBHMKAN_01581 9e-49 yedF O Belongs to the sulfur carrier protein TusA family
GDBHMKAN_01582 4.5e-08 S Protein of unknown function (DUF3343)
GDBHMKAN_01583 1.6e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
GDBHMKAN_01584 3.9e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GDBHMKAN_01585 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GDBHMKAN_01586 2.1e-36 yrzL S Belongs to the UPF0297 family
GDBHMKAN_01587 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GDBHMKAN_01588 1.9e-33 yrzB S Belongs to the UPF0473 family
GDBHMKAN_01589 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GDBHMKAN_01590 2.3e-16 cvpA S Colicin V production protein
GDBHMKAN_01591 6.5e-311 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GDBHMKAN_01592 9.9e-41 trxA O Belongs to the thioredoxin family
GDBHMKAN_01593 4e-216 XK27_09600 V ABC transporter, ATP-binding protein
GDBHMKAN_01594 4.1e-229 V ABC transporter transmembrane region
GDBHMKAN_01596 2.8e-95 S Domain of unknown function DUF87
GDBHMKAN_01598 4.7e-106 yxeH S hydrolase
GDBHMKAN_01600 7.1e-172 dltB M MBOAT, membrane-bound O-acyltransferase family
GDBHMKAN_01601 2.1e-153 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GDBHMKAN_01602 3.3e-09 bta 1.8.1.8 CO transport accessory protein
GDBHMKAN_01603 9e-114 K response regulator
GDBHMKAN_01604 1.5e-272 vicK 2.7.13.3 T Histidine kinase
GDBHMKAN_01605 1.3e-102 yycH S YycH protein
GDBHMKAN_01606 2.1e-79 yycI S YycH protein
GDBHMKAN_01607 6.8e-30 yyaQ S YjbR
GDBHMKAN_01608 1.7e-116 vicX 3.1.26.11 S domain protein
GDBHMKAN_01609 9.6e-146 htrA 3.4.21.107 O serine protease
GDBHMKAN_01610 9.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GDBHMKAN_01611 6.7e-206 G glycerol-3-phosphate transporter
GDBHMKAN_01612 3.3e-134 S interspecies interaction between organisms
GDBHMKAN_01613 1.5e-63 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
GDBHMKAN_01614 9.2e-90 asp1 S Accessory Sec system protein Asp1
GDBHMKAN_01615 7.5e-105 asp2 3.4.11.5 S Accessory Sec system protein Asp2
GDBHMKAN_01616 1e-32 asp3 S Accessory Sec system protein Asp3
GDBHMKAN_01617 2.3e-246 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GDBHMKAN_01620 8.8e-24 3.2.1.18 GH33 M Rib/alpha-like repeat
GDBHMKAN_01622 6.4e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
GDBHMKAN_01623 9e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GDBHMKAN_01624 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GDBHMKAN_01625 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GDBHMKAN_01626 1.5e-144 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GDBHMKAN_01627 5.4e-13
GDBHMKAN_01628 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
GDBHMKAN_01629 2.9e-274 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GDBHMKAN_01630 1.5e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GDBHMKAN_01631 7.8e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GDBHMKAN_01632 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GDBHMKAN_01633 2.8e-79 dnaB L replication initiation and membrane attachment
GDBHMKAN_01634 9.7e-108 dnaI L Primosomal protein DnaI
GDBHMKAN_01635 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GDBHMKAN_01636 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GDBHMKAN_01637 2.9e-25 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GDBHMKAN_01638 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GDBHMKAN_01639 2.5e-71 yqeG S HAD phosphatase, family IIIA
GDBHMKAN_01640 3e-180 yqeH S Ribosome biogenesis GTPase YqeH
GDBHMKAN_01641 1e-29 yhbY J RNA-binding protein
GDBHMKAN_01642 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GDBHMKAN_01643 4.7e-71 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
GDBHMKAN_01644 5.1e-49 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GDBHMKAN_01645 5.5e-82 H Nodulation protein S (NodS)
GDBHMKAN_01646 1.3e-122 ylbM S Belongs to the UPF0348 family
GDBHMKAN_01647 3.5e-57 yceD S Uncharacterized ACR, COG1399
GDBHMKAN_01648 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GDBHMKAN_01649 3.9e-53 EGP Major facilitator Superfamily
GDBHMKAN_01650 3.9e-58 S Haloacid dehalogenase-like hydrolase
GDBHMKAN_01651 1.6e-88 yvyE 3.4.13.9 S YigZ family
GDBHMKAN_01652 9.5e-38 S CAAX protease self-immunity
GDBHMKAN_01653 5.8e-117 cps1D M Domain of unknown function (DUF4422)
GDBHMKAN_01654 8.6e-62 S Glycosyltransferase like family 2
GDBHMKAN_01655 3.6e-141 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GDBHMKAN_01656 9.4e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GDBHMKAN_01657 1.8e-179 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GDBHMKAN_01658 2.1e-130 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GDBHMKAN_01659 4.6e-117 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
GDBHMKAN_01660 4.4e-27 S zinc-ribbon domain
GDBHMKAN_01661 2.5e-83 S response to antibiotic
GDBHMKAN_01662 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GDBHMKAN_01663 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GDBHMKAN_01664 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GDBHMKAN_01665 1.1e-249 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GDBHMKAN_01666 2.3e-213 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GDBHMKAN_01667 3e-44 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GDBHMKAN_01668 6.6e-87 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GDBHMKAN_01669 2.8e-167 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
GDBHMKAN_01670 5.6e-120 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
GDBHMKAN_01671 1.4e-181 gatC G PTS system sugar-specific permease component
GDBHMKAN_01672 9.2e-36 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
GDBHMKAN_01673 1e-38 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GDBHMKAN_01674 5.7e-64 D peptidase
GDBHMKAN_01675 5.6e-117 S Glycosyl transferase family 2
GDBHMKAN_01676 5.6e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
GDBHMKAN_01677 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GDBHMKAN_01678 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GDBHMKAN_01679 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
GDBHMKAN_01680 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GDBHMKAN_01681 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GDBHMKAN_01682 8.4e-154 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GDBHMKAN_01683 9e-20 yaaA S S4 domain protein YaaA
GDBHMKAN_01684 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GDBHMKAN_01685 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GDBHMKAN_01686 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
GDBHMKAN_01687 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GDBHMKAN_01688 4.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GDBHMKAN_01689 1.1e-199 nupG F Nucleoside
GDBHMKAN_01690 1.5e-122 MA20_14895 S Conserved hypothetical protein 698
GDBHMKAN_01691 1.7e-53 K LysR substrate binding domain
GDBHMKAN_01692 1.8e-07
GDBHMKAN_01693 1.8e-65 yxkH G Polysaccharide deacetylase
GDBHMKAN_01694 9e-30 yqkB S Belongs to the HesB IscA family
GDBHMKAN_01695 1.5e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GDBHMKAN_01696 6.1e-101 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GDBHMKAN_01697 1.4e-52 rplQ J Ribosomal protein L17
GDBHMKAN_01698 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GDBHMKAN_01699 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GDBHMKAN_01700 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GDBHMKAN_01701 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GDBHMKAN_01702 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GDBHMKAN_01703 3.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GDBHMKAN_01704 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GDBHMKAN_01705 1e-67 rplO J Binds to the 23S rRNA
GDBHMKAN_01706 2.1e-22 rpmD J Ribosomal protein L30
GDBHMKAN_01707 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GDBHMKAN_01708 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GDBHMKAN_01709 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GDBHMKAN_01710 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GDBHMKAN_01711 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GDBHMKAN_01712 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GDBHMKAN_01713 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GDBHMKAN_01714 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GDBHMKAN_01715 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GDBHMKAN_01716 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
GDBHMKAN_01717 3.1e-72 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GDBHMKAN_01718 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GDBHMKAN_01719 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GDBHMKAN_01720 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GDBHMKAN_01721 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GDBHMKAN_01722 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GDBHMKAN_01723 1e-100 rplD J Forms part of the polypeptide exit tunnel
GDBHMKAN_01724 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GDBHMKAN_01725 3.7e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
GDBHMKAN_01726 6.2e-166 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GDBHMKAN_01727 6.5e-79 K rpiR family
GDBHMKAN_01728 2.2e-53 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
GDBHMKAN_01729 8.5e-147 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
GDBHMKAN_01730 4.9e-21 K Acetyltransferase (GNAT) domain
GDBHMKAN_01731 6.4e-182 steT E amino acid
GDBHMKAN_01732 9.6e-78 glnP P ABC transporter permease
GDBHMKAN_01733 1.2e-85 gluC P ABC transporter permease
GDBHMKAN_01734 1.1e-99 glnH ET ABC transporter
GDBHMKAN_01735 3.3e-103 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GDBHMKAN_01736 1.3e-09
GDBHMKAN_01737 5e-98
GDBHMKAN_01738 3.1e-09 3.2.1.14 GH18
GDBHMKAN_01739 2.4e-53 zur P Belongs to the Fur family
GDBHMKAN_01740 3.7e-212 yfnA E Amino Acid
GDBHMKAN_01741 8.3e-41 S VanZ like family
GDBHMKAN_01742 1.5e-119 yebC K Transcriptional regulatory protein
GDBHMKAN_01743 7.9e-102 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GDBHMKAN_01744 3.1e-120 comGA NU Type II IV secretion system protein
GDBHMKAN_01745 5.7e-98 comGB NU type II secretion system
GDBHMKAN_01746 1.2e-27 comGC U competence protein ComGC
GDBHMKAN_01747 5.6e-13
GDBHMKAN_01748 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
GDBHMKAN_01749 1.5e-27 yazA L GIY-YIG catalytic domain protein
GDBHMKAN_01750 7.2e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
GDBHMKAN_01751 3.6e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GDBHMKAN_01752 3.1e-79 sip L Belongs to the 'phage' integrase family
GDBHMKAN_01753 5.2e-103 dam2 2.1.1.72 L DNA methyltransferase
GDBHMKAN_01754 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GDBHMKAN_01755 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GDBHMKAN_01756 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GDBHMKAN_01757 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GDBHMKAN_01758 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
GDBHMKAN_01759 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GDBHMKAN_01760 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GDBHMKAN_01761 7e-71 yacP S YacP-like NYN domain
GDBHMKAN_01762 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GDBHMKAN_01763 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GDBHMKAN_01764 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GDBHMKAN_01765 4.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GDBHMKAN_01766 8.2e-154 yacL S domain protein
GDBHMKAN_01767 1.6e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GDBHMKAN_01768 6.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
GDBHMKAN_01769 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
GDBHMKAN_01770 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
GDBHMKAN_01771 3.9e-30 S Enterocin A Immunity
GDBHMKAN_01772 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GDBHMKAN_01773 4.5e-129 mleP2 S Sodium Bile acid symporter family
GDBHMKAN_01774 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GDBHMKAN_01776 3.6e-44 ydcK S Belongs to the SprT family
GDBHMKAN_01777 2.8e-251 yhgF K Tex-like protein N-terminal domain protein
GDBHMKAN_01778 1.4e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GDBHMKAN_01779 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GDBHMKAN_01780 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GDBHMKAN_01781 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
GDBHMKAN_01782 4.6e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GDBHMKAN_01784 1.1e-07
GDBHMKAN_01785 1.6e-197 dtpT U amino acid peptide transporter
GDBHMKAN_01788 5.7e-47 S Plasmid replication protein
GDBHMKAN_01789 3.6e-24 L Eco57I restriction-modification methylase
GDBHMKAN_01790 5.8e-57 spoVK O ATPase family associated with various cellular activities (AAA)
GDBHMKAN_01794 5.3e-12 D Antitoxin component of a toxin-antitoxin (TA) module
GDBHMKAN_01795 3.9e-111 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GDBHMKAN_01796 8e-10
GDBHMKAN_01797 9.9e-34
GDBHMKAN_01799 1.1e-40 XK27_10050 K Peptidase S24-like
GDBHMKAN_01803 1.3e-14 cro K Helix-turn-helix XRE-family like proteins
GDBHMKAN_01804 7.8e-73 ps308 K AntA/AntB antirepressor
GDBHMKAN_01810 3.6e-54 S Putative HNHc nuclease
GDBHMKAN_01811 4e-32 L N-terminal phage replisome organiser (Phage_rep_org_N)
GDBHMKAN_01814 1.6e-25
GDBHMKAN_01815 9.7e-71
GDBHMKAN_01828 2.3e-25 arpU S Phage transcriptional regulator, ArpU family
GDBHMKAN_01830 5.4e-22
GDBHMKAN_01831 8.7e-26 V HNH nucleases
GDBHMKAN_01832 3.8e-14
GDBHMKAN_01833 6.2e-182 S Terminase
GDBHMKAN_01834 8.5e-82 S Phage portal protein
GDBHMKAN_01835 7.6e-55 clpP 3.4.21.92 OU Clp protease
GDBHMKAN_01837 1.1e-154 S peptidoglycan catabolic process
GDBHMKAN_01838 8.7e-32 S phage tail
GDBHMKAN_01839 2e-60 S Prophage endopeptidase tail
GDBHMKAN_01841 1.2e-67 S Domain of unknown function (DUF2479)
GDBHMKAN_01847 7e-22 S Bacteriophage holin of superfamily 6 (Holin_LLH)
GDBHMKAN_01848 3e-117 S N-acetylmuramoyl-L-alanine amidase activity
GDBHMKAN_01849 2.9e-160 Z012_01130 S Fic/DOC family
GDBHMKAN_01850 1.1e-58 3.1.21.3 V Type I restriction modification DNA specificity domain
GDBHMKAN_01851 2e-129 L Belongs to the 'phage' integrase family
GDBHMKAN_01852 2.2e-101 3.1.21.3 V Type I restriction modification DNA specificity domain
GDBHMKAN_01853 3e-210 hsdM 2.1.1.72 V type I restriction-modification system
GDBHMKAN_01854 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
GDBHMKAN_01856 5.1e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
GDBHMKAN_01857 3.7e-56 3.6.1.27 I Acid phosphatase homologues
GDBHMKAN_01858 1.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
GDBHMKAN_01859 1.2e-16 J GNAT acetyltransferase
GDBHMKAN_01860 2.4e-34 2.3.1.178 M GNAT acetyltransferase
GDBHMKAN_01862 2.1e-196 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GDBHMKAN_01863 1e-64 ypsA S Belongs to the UPF0398 family
GDBHMKAN_01864 6.3e-188 nhaC C Na H antiporter NhaC
GDBHMKAN_01865 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GDBHMKAN_01866 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
GDBHMKAN_01867 5.3e-174 cas3 L CRISPR-associated helicase cas3
GDBHMKAN_01868 1.2e-151 casA L the current gene model (or a revised gene model) may contain a frame shift
GDBHMKAN_01869 8.1e-22 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
GDBHMKAN_01870 1.5e-112 casC L CT1975-like protein
GDBHMKAN_01871 5.6e-60 casD S CRISPR-associated protein (Cas_Cas5)
GDBHMKAN_01872 6.2e-61 casE S CRISPR_assoc
GDBHMKAN_01873 1.6e-118 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GDBHMKAN_01874 1.7e-82 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
GDBHMKAN_01875 3e-17 L hmm pf00665
GDBHMKAN_01877 3e-36
GDBHMKAN_01878 9.8e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GDBHMKAN_01879 4.2e-61 marR K Transcriptional regulator, MarR family
GDBHMKAN_01880 4.9e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GDBHMKAN_01881 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GDBHMKAN_01882 5e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
GDBHMKAN_01883 1.1e-98 IQ reductase
GDBHMKAN_01884 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GDBHMKAN_01885 1.7e-46 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GDBHMKAN_01886 1e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GDBHMKAN_01887 4.2e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
GDBHMKAN_01888 8e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GDBHMKAN_01889 5.1e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
GDBHMKAN_01890 7.1e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
GDBHMKAN_01891 2.3e-140 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
GDBHMKAN_01892 1.4e-61 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GDBHMKAN_01893 2.1e-24 relB L RelB antitoxin
GDBHMKAN_01894 4.9e-172 S Putative peptidoglycan binding domain
GDBHMKAN_01895 7.5e-191 KLT serine threonine protein kinase
GDBHMKAN_01896 3.3e-90 stp 3.1.3.16 T phosphatase
GDBHMKAN_01897 3.7e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GDBHMKAN_01898 1.3e-139 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GDBHMKAN_01899 7.8e-287 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GDBHMKAN_01900 2.2e-120 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GDBHMKAN_01901 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GDBHMKAN_01902 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GDBHMKAN_01903 1.8e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GDBHMKAN_01904 4e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GDBHMKAN_01905 0.0 lacL 3.2.1.23 G -beta-galactosidase
GDBHMKAN_01906 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
GDBHMKAN_01907 1e-193 cydA 1.10.3.14 C ubiquinol oxidase
GDBHMKAN_01908 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
GDBHMKAN_01909 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GDBHMKAN_01910 1e-219 cydD CO ABC transporter transmembrane region
GDBHMKAN_01911 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GDBHMKAN_01912 3.3e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
GDBHMKAN_01913 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
GDBHMKAN_01914 6.8e-144 pbuO_1 S Permease family
GDBHMKAN_01916 6.2e-42 L Helicase C-terminal domain protein
GDBHMKAN_01917 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GDBHMKAN_01918 1.4e-28 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GDBHMKAN_01919 1e-150 dltB M MBOAT, membrane-bound O-acyltransferase family
GDBHMKAN_01920 1.4e-17 dltB M MBOAT, membrane-bound O-acyltransferase family
GDBHMKAN_01921 2e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GDBHMKAN_01922 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
GDBHMKAN_01923 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
GDBHMKAN_01924 1e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GDBHMKAN_01925 1.1e-29 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GDBHMKAN_01926 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GDBHMKAN_01927 3.5e-153 phoH T phosphate starvation-inducible protein PhoH
GDBHMKAN_01928 2.6e-83 lytH 3.5.1.28 M Ami_3
GDBHMKAN_01929 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GDBHMKAN_01930 7.7e-12 M Lysin motif
GDBHMKAN_01932 3.5e-113 S Aldo keto reductase
GDBHMKAN_01933 4.2e-35 K helix_turn_helix, mercury resistance
GDBHMKAN_01934 1.6e-133 yvgN C Aldo keto reductase
GDBHMKAN_01935 4.7e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GDBHMKAN_01936 7.5e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GDBHMKAN_01937 2.2e-276 yfmR S ABC transporter, ATP-binding protein
GDBHMKAN_01938 1.1e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GDBHMKAN_01939 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GDBHMKAN_01940 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GDBHMKAN_01941 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
GDBHMKAN_01942 3.7e-26 radC L DNA repair protein
GDBHMKAN_01944 4.6e-37
GDBHMKAN_01945 2.6e-16 S RelB antitoxin
GDBHMKAN_01948 1.8e-106 L Belongs to the 'phage' integrase family
GDBHMKAN_01949 1.7e-231 tetP J elongation factor G
GDBHMKAN_01950 0.0 asnB 6.3.5.4 E Asparagine synthase
GDBHMKAN_01951 1.6e-60 yiiE S Protein of unknown function (DUF1211)
GDBHMKAN_01952 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GDBHMKAN_01953 4.3e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
GDBHMKAN_01954 3.6e-17 yneR
GDBHMKAN_01955 8.7e-231 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GDBHMKAN_01956 5.5e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
GDBHMKAN_01957 9.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GDBHMKAN_01958 1.7e-152 mdtG EGP Major facilitator Superfamily
GDBHMKAN_01959 5.9e-15 K regulatory protein TetR
GDBHMKAN_01960 4.8e-109 glcU U sugar transport
GDBHMKAN_01961 1.6e-167 yjjP S Putative threonine/serine exporter
GDBHMKAN_01962 1.5e-68 2.3.1.178 J Acetyltransferase (GNAT) domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)