ORF_ID e_value Gene_name EC_number CAZy COGs Description
KIAEFMKN_00001 3.6e-249 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KIAEFMKN_00002 4.5e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KIAEFMKN_00003 2.4e-33 yaaA S S4 domain
KIAEFMKN_00004 1.6e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KIAEFMKN_00005 1.3e-10 yaaB S Domain of unknown function (DUF370)
KIAEFMKN_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIAEFMKN_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIAEFMKN_00008 8.9e-198 M1-161 T HD domain
KIAEFMKN_00009 4.3e-42 S COG NOG14552 non supervised orthologous group
KIAEFMKN_00012 1.7e-41
KIAEFMKN_00013 3.9e-36 csfB S Inhibitor of sigma-G Gin
KIAEFMKN_00014 3.2e-286 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KIAEFMKN_00015 3.8e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KIAEFMKN_00016 9.8e-55 yaaQ S protein conserved in bacteria
KIAEFMKN_00017 1.8e-72 yaaR S protein conserved in bacteria
KIAEFMKN_00018 4.3e-186 holB 2.7.7.7 L DNA polymerase III
KIAEFMKN_00019 1.7e-148 yaaT S stage 0 sporulation protein
KIAEFMKN_00020 4.5e-67 yabA L Involved in initiation control of chromosome replication
KIAEFMKN_00021 2.2e-139 yabB 2.1.1.223 S Conserved hypothetical protein 95
KIAEFMKN_00022 1.6e-48 yazA L endonuclease containing a URI domain
KIAEFMKN_00023 5.3e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KIAEFMKN_00024 2.1e-53 abrB K COG2002 Regulators of stationary sporulation gene expression
KIAEFMKN_00025 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KIAEFMKN_00026 1.6e-154 tatD L hydrolase, TatD
KIAEFMKN_00027 8.5e-105 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KIAEFMKN_00028 1.8e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KIAEFMKN_00029 8.7e-167 yabG S peptidase
KIAEFMKN_00030 2.4e-37 veg S protein conserved in bacteria
KIAEFMKN_00031 2.2e-34 sspF S DNA topological change
KIAEFMKN_00032 3.2e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KIAEFMKN_00033 2.9e-154 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KIAEFMKN_00034 3.2e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KIAEFMKN_00035 3.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KIAEFMKN_00037 2.9e-224 S Psort location CytoplasmicMembrane, score
KIAEFMKN_00038 5.5e-40 V Abc transporter
KIAEFMKN_00039 1.5e-82
KIAEFMKN_00040 3.5e-247 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KIAEFMKN_00041 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KIAEFMKN_00042 6.3e-111 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KIAEFMKN_00043 9.3e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KIAEFMKN_00044 1.7e-37 yabK S Peptide ABC transporter permease
KIAEFMKN_00045 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KIAEFMKN_00046 6.2e-91 spoVT K stage V sporulation protein
KIAEFMKN_00047 1.1e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KIAEFMKN_00048 4.9e-196 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KIAEFMKN_00049 4e-41 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KIAEFMKN_00050 4.7e-51 yabP S Sporulation protein YabP
KIAEFMKN_00051 3.7e-111 yabQ S spore cortex biosynthesis protein
KIAEFMKN_00052 1.9e-60 divIC D Septum formation initiator
KIAEFMKN_00053 6.9e-53 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KIAEFMKN_00055 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KIAEFMKN_00056 8.7e-120 yabS S protein containing a von Willebrand factor type A (vWA) domain
KIAEFMKN_00057 2e-167 KLT serine threonine protein kinase
KIAEFMKN_00058 1.2e-277 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KIAEFMKN_00059 2.9e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KIAEFMKN_00060 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KIAEFMKN_00061 3.8e-142 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KIAEFMKN_00062 4.7e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KIAEFMKN_00063 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KIAEFMKN_00064 1.3e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KIAEFMKN_00065 4.2e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KIAEFMKN_00066 1.6e-96 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KIAEFMKN_00067 3.5e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KIAEFMKN_00068 4.3e-42 S COG NOG14552 non supervised orthologous group
KIAEFMKN_00069 5.3e-43
KIAEFMKN_00072 1.6e-08
KIAEFMKN_00073 4e-08
KIAEFMKN_00077 4.3e-42 S COG NOG14552 non supervised orthologous group
KIAEFMKN_00078 5.3e-43
KIAEFMKN_00079 2.7e-182 yaaC S YaaC-like Protein
KIAEFMKN_00080 1.5e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KIAEFMKN_00081 3.2e-250 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KIAEFMKN_00082 1.6e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KIAEFMKN_00083 4.4e-103 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KIAEFMKN_00084 9.2e-210 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KIAEFMKN_00085 2.9e-09
KIAEFMKN_00086 3.7e-125 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KIAEFMKN_00087 5.4e-118 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KIAEFMKN_00088 2.6e-252 yaaH M Glycoside Hydrolase Family
KIAEFMKN_00090 1e-87 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KIAEFMKN_00091 7e-311 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KIAEFMKN_00092 1.3e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KIAEFMKN_00093 1.5e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KIAEFMKN_00094 6.9e-09 S Protein of unknown function (DUF2508)
KIAEFMKN_00095 5.7e-37 bofA S Sigma-K factor-processing regulatory protein BofA
KIAEFMKN_00096 1.6e-41 S COG NOG14552 non supervised orthologous group
KIAEFMKN_00099 1.7e-41
KIAEFMKN_00100 5.3e-44 S Protein of unknown function (DUF3969)
KIAEFMKN_00102 5.4e-75 ctsR K Belongs to the CtsR family
KIAEFMKN_00103 1.4e-101 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KIAEFMKN_00104 7.8e-194 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KIAEFMKN_00105 0.0 clpC O Belongs to the ClpA ClpB family
KIAEFMKN_00107 3.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KIAEFMKN_00108 4e-198 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KIAEFMKN_00109 1.5e-121 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KIAEFMKN_00110 1.1e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KIAEFMKN_00111 1.9e-283 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KIAEFMKN_00112 6.3e-109 cysE 2.3.1.30 E Serine acetyltransferase
KIAEFMKN_00113 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KIAEFMKN_00114 7.9e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KIAEFMKN_00115 3.3e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KIAEFMKN_00116 8.7e-90 yacP S RNA-binding protein containing a PIN domain
KIAEFMKN_00117 2.4e-113 sigH K Belongs to the sigma-70 factor family
KIAEFMKN_00119 1e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KIAEFMKN_00120 1.4e-95 nusG K Participates in transcription elongation, termination and antitermination
KIAEFMKN_00121 1.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KIAEFMKN_00122 9.5e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KIAEFMKN_00124 5.4e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KIAEFMKN_00125 1.3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KIAEFMKN_00126 4.2e-112 rsmC 2.1.1.172 J Methyltransferase
KIAEFMKN_00127 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIAEFMKN_00128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIAEFMKN_00129 2.6e-36 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
KIAEFMKN_00130 8.6e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KIAEFMKN_00131 9.3e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KIAEFMKN_00132 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KIAEFMKN_00133 2.7e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KIAEFMKN_00134 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KIAEFMKN_00135 1.7e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KIAEFMKN_00136 5.1e-105 rplD J Forms part of the polypeptide exit tunnel
KIAEFMKN_00137 2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KIAEFMKN_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KIAEFMKN_00139 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KIAEFMKN_00140 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KIAEFMKN_00141 2.3e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KIAEFMKN_00142 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KIAEFMKN_00143 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KIAEFMKN_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KIAEFMKN_00145 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KIAEFMKN_00146 1.7e-57 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KIAEFMKN_00147 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KIAEFMKN_00148 5.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KIAEFMKN_00149 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KIAEFMKN_00150 1.7e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KIAEFMKN_00151 4.7e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KIAEFMKN_00152 6.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KIAEFMKN_00153 7e-23 rpmD J Ribosomal protein L30
KIAEFMKN_00154 1.2e-71 rplO J binds to the 23S rRNA
KIAEFMKN_00155 3.1e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KIAEFMKN_00156 3.7e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KIAEFMKN_00157 2.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KIAEFMKN_00158 1.8e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KIAEFMKN_00159 5.2e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KIAEFMKN_00160 6.9e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIAEFMKN_00161 2.8e-59 rplQ J Ribosomal protein L17
KIAEFMKN_00163 2.7e-157 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIAEFMKN_00164 6.4e-162 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIAEFMKN_00165 6e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIAEFMKN_00166 3.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KIAEFMKN_00167 9.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KIAEFMKN_00168 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KIAEFMKN_00169 0.0 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KIAEFMKN_00170 0.0 S type I phosphodiesterase nucleotide pyrophosphatase
KIAEFMKN_00172 2.9e-226 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KIAEFMKN_00173 1.4e-110 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
KIAEFMKN_00174 1.9e-275 lysP E amino acid
KIAEFMKN_00175 8.8e-83 ybaK S Protein of unknown function (DUF2521)
KIAEFMKN_00176 6.2e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KIAEFMKN_00177 1.9e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KIAEFMKN_00178 4.8e-70 gerD S Spore gernimation protein
KIAEFMKN_00179 4.8e-106 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KIAEFMKN_00180 2.6e-210 S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
KIAEFMKN_00181 1.1e-172 K Transcriptional regulator
KIAEFMKN_00183 2.5e-15 S Ribbon-helix-helix protein, copG family
KIAEFMKN_00184 5.1e-212 L Transposase
KIAEFMKN_00185 5.5e-138 pdaB 3.5.1.104 G xylanase chitin deacetylase
KIAEFMKN_00186 2.6e-30
KIAEFMKN_00187 8.4e-265 cydA 1.10.3.14 C oxidase, subunit
KIAEFMKN_00188 4.9e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KIAEFMKN_00189 0.0 cydD V ATP-binding
KIAEFMKN_00190 0.0 cydD V ATP-binding protein
KIAEFMKN_00191 3.3e-141 IQ Enoyl-(Acyl carrier protein) reductase
KIAEFMKN_00192 4.3e-42 S COG NOG14552 non supervised orthologous group
KIAEFMKN_00193 3.5e-42
KIAEFMKN_00198 1.7e-07
KIAEFMKN_00199 1.5e-07
KIAEFMKN_00203 1.1e-169 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KIAEFMKN_00205 7.2e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KIAEFMKN_00206 5.8e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KIAEFMKN_00207 9.4e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KIAEFMKN_00208 9.3e-223 ybbR S protein conserved in bacteria
KIAEFMKN_00209 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KIAEFMKN_00210 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KIAEFMKN_00212 5.1e-98 M1-431 S Protein of unknown function (DUF1706)
KIAEFMKN_00213 3.3e-217 G Major facilitator Superfamily
KIAEFMKN_00214 9.3e-85 S Pfam:DUF1399
KIAEFMKN_00215 1e-128 EGP Major facilitator Superfamily
KIAEFMKN_00216 2.4e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KIAEFMKN_00217 1.6e-260 NT Chemoreceptor zinc-binding domain
KIAEFMKN_00218 8.3e-114 S Putative adhesin
KIAEFMKN_00219 3.9e-96 S Protein of unknown function (DUF1700)
KIAEFMKN_00220 1.3e-54 K PadR family transcriptional regulator
KIAEFMKN_00221 2e-183 NT chemotaxis protein
KIAEFMKN_00222 5.3e-251 EGP Major facilitator superfamily
KIAEFMKN_00223 1.3e-102 Q Isochorismatase family
KIAEFMKN_00224 1.1e-107 K Transcriptional regulator
KIAEFMKN_00225 6.4e-60
KIAEFMKN_00226 6e-127
KIAEFMKN_00227 5.2e-44 ltaA 4.1.2.48 E L-allo-threonine aldolase activity
KIAEFMKN_00228 1.4e-212 EGP Major Facilitator Superfamily
KIAEFMKN_00229 3.9e-170 F ATP-grasp domain
KIAEFMKN_00230 3.2e-211 K helix_turn_helix, Arsenical Resistance Operon Repressor
KIAEFMKN_00231 1.7e-51 ykvR S Protein of unknown function (DUF3219)
KIAEFMKN_00232 7.2e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIAEFMKN_00234 1.2e-217 yjbB G Major Facilitator Superfamily
KIAEFMKN_00236 3.6e-18 rimJ 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KIAEFMKN_00237 0.0 L Domain of unknown function (DUF4277)
KIAEFMKN_00238 1.1e-65 rimJ 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KIAEFMKN_00240 1.1e-86 2.3.1.128 J Acetyltransferase (GNAT) domain
KIAEFMKN_00241 1.3e-72 3.6.1.55 F GDP-mannose mannosyl hydrolase activity
KIAEFMKN_00242 1.7e-116 E lactoylglutathione lyase activity
KIAEFMKN_00243 1.6e-233 lmrP E Transmembrane secretion effector
KIAEFMKN_00244 1.1e-74 yycN 2.3.1.128, 2.3.1.57 K FR47-like protein
KIAEFMKN_00245 1.4e-73 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KIAEFMKN_00246 3e-248 L PFAM Transposase, IS4-like
KIAEFMKN_00247 1.8e-50 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KIAEFMKN_00248 1.7e-123 V CAAX protease self-immunity
KIAEFMKN_00249 4.4e-09
KIAEFMKN_00250 3.6e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 I Hydroxymethylglutaryl-coenzyme A reductase
KIAEFMKN_00252 1.1e-220 mvaS 2.3.3.10 I synthase
KIAEFMKN_00253 4.8e-213 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
KIAEFMKN_00254 4.2e-53 S DsrE/DsrF-like family
KIAEFMKN_00255 1.5e-77
KIAEFMKN_00256 5.6e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIAEFMKN_00257 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KIAEFMKN_00258 3.5e-177 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KIAEFMKN_00259 5.8e-275 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
KIAEFMKN_00260 2.8e-82 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KIAEFMKN_00261 4.5e-266 treP 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KIAEFMKN_00262 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KIAEFMKN_00263 8.2e-131 treR K transcriptional
KIAEFMKN_00264 2.4e-229 EG COG2610 H gluconate symporter and related permeases
KIAEFMKN_00265 4.4e-307 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KIAEFMKN_00266 2.2e-125 gntR K transcriptional
KIAEFMKN_00267 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KIAEFMKN_00269 1.7e-81 fld C Flavodoxin
KIAEFMKN_00270 1.3e-199 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KIAEFMKN_00271 1.1e-138 4.1.99.16, 4.2.3.22, 4.2.3.75 T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KIAEFMKN_00272 0.0 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KIAEFMKN_00273 5.6e-30 P Heavy-metal-associated domain
KIAEFMKN_00275 0.0 nrdA 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KIAEFMKN_00276 1.6e-87 fld C Flavodoxin
KIAEFMKN_00277 5.2e-195 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KIAEFMKN_00278 8.9e-110 plsY 2.3.1.15 I Belongs to the PlsY family
KIAEFMKN_00279 7.3e-208 crtQ M Glycosyl transferase family 21
KIAEFMKN_00280 8.6e-149 S transposase or invertase
KIAEFMKN_00281 6.1e-93 Q Thioesterase superfamily
KIAEFMKN_00282 2.8e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KIAEFMKN_00283 1e-48 sugE P Multidrug resistance protein
KIAEFMKN_00284 6.6e-54 ykkC P Multidrug resistance protein
KIAEFMKN_00285 2e-138 yfcA S membrane transporter protein
KIAEFMKN_00286 1.8e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIAEFMKN_00287 2.6e-178 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIAEFMKN_00288 3.2e-170 fhuD P Periplasmic binding protein
KIAEFMKN_00289 4.9e-148 fhuC 3.6.3.34 HP ABC transporter
KIAEFMKN_00290 4e-195 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KIAEFMKN_00291 6.2e-114
KIAEFMKN_00293 3e-105
KIAEFMKN_00294 2e-106
KIAEFMKN_00295 3.8e-128 yeeN K transcriptional regulatory protein
KIAEFMKN_00296 3.4e-191 T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
KIAEFMKN_00297 8.9e-242 MA20_26760 1.3.8.7 I COG1960 Acyl-CoA dehydrogenases
KIAEFMKN_00298 2.6e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIAEFMKN_00299 4.9e-175 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KIAEFMKN_00300 1.5e-74 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KIAEFMKN_00301 6.7e-96 K Transcriptional regulator
KIAEFMKN_00303 3.1e-53 S Thioesterase-like superfamily
KIAEFMKN_00304 3.9e-198 S Phosphotransferase enzyme family
KIAEFMKN_00305 1.6e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KIAEFMKN_00306 2.7e-260 yobO M Pectate lyase superfamily protein
KIAEFMKN_00307 3.7e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KIAEFMKN_00308 6e-140 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KIAEFMKN_00309 3.7e-134 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KIAEFMKN_00310 7.7e-109 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KIAEFMKN_00311 7e-95 ywhH S Aminoacyl-tRNA editing domain
KIAEFMKN_00312 1.7e-204 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KIAEFMKN_00313 0.0 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KIAEFMKN_00314 5.1e-190 2.7.7.65 T Diguanylate cyclase, GGDEF domain
KIAEFMKN_00316 1.3e-165 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KIAEFMKN_00317 1.5e-158 S Nuclease-related domain
KIAEFMKN_00318 8.4e-45
KIAEFMKN_00319 2.6e-30
KIAEFMKN_00320 6.7e-165 czcD P COG1230 Co Zn Cd efflux system component
KIAEFMKN_00321 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KIAEFMKN_00322 2.2e-114 M Glycosyltransferase like family 2
KIAEFMKN_00323 1.4e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases C terminal
KIAEFMKN_00324 4.5e-180 mvaD 4.1.1.33 I GHMP kinases N terminal domain
KIAEFMKN_00325 1.2e-192 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases C terminal
KIAEFMKN_00328 5.9e-112 yhfK GM NmrA-like family
KIAEFMKN_00329 6.4e-22
KIAEFMKN_00330 4e-75 S protein conserved in bacteria
KIAEFMKN_00331 5.2e-97 ET Bacterial periplasmic substrate-binding proteins
KIAEFMKN_00332 1.5e-86 arpJ E Binding-protein-dependent transport system inner membrane component
KIAEFMKN_00333 5.6e-111 glnQ 3.6.3.21 E ABC transporter
KIAEFMKN_00334 7.4e-143 glmS2 G Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KIAEFMKN_00335 1.3e-83 frlR K UTRA
KIAEFMKN_00336 2.9e-111 frlD1 G pfkB family carbohydrate kinase
KIAEFMKN_00337 9.5e-101 ET Bacterial periplasmic substrate-binding proteins
KIAEFMKN_00338 2.4e-76 frlR K UTRA
KIAEFMKN_00339 1.5e-104 G Xylose isomerase-like TIM barrel
KIAEFMKN_00340 6.1e-137 glmS2 M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KIAEFMKN_00341 8.7e-231 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KIAEFMKN_00342 3.2e-110 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KIAEFMKN_00343 1.5e-37 gcvR T Belongs to the UPF0237 family
KIAEFMKN_00344 4.1e-248 XK27_08635 S UPF0210 protein
KIAEFMKN_00345 7.5e-194 ptxS K transcriptional
KIAEFMKN_00346 3.4e-135 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
KIAEFMKN_00347 8.8e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KIAEFMKN_00348 7.4e-239 G Major Facilitator Superfamily
KIAEFMKN_00349 2.9e-92 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
KIAEFMKN_00350 3.1e-93 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
KIAEFMKN_00352 6.8e-84 cotF M Spore coat protein
KIAEFMKN_00353 1.4e-175 iolS C Aldo keto reductase
KIAEFMKN_00354 1.9e-98 ydjA C Nitroreductase family
KIAEFMKN_00355 5.2e-262 S PFAM Uncharacterised protein family UPF0236
KIAEFMKN_00356 1.1e-253 E COG1113 Gamma-aminobutyrate permease and related permeases
KIAEFMKN_00357 8.5e-17
KIAEFMKN_00358 7.3e-275 dtpT E amino acid peptide transporter
KIAEFMKN_00359 3.5e-277 lysP E amino acid
KIAEFMKN_00360 4.3e-98 puuR K Cupin domain
KIAEFMKN_00361 1.6e-210 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KIAEFMKN_00362 1.8e-139 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
KIAEFMKN_00363 9.2e-139 potC E COG1177 ABC-type spermidine putrescine transport system, permease component II
KIAEFMKN_00364 6.4e-204 potD E COG0687 Spermidine putrescine-binding periplasmic protein
KIAEFMKN_00365 5.6e-269 H HemY protein
KIAEFMKN_00366 9.1e-251 E amino acid
KIAEFMKN_00367 6.1e-134 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KIAEFMKN_00368 3e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KIAEFMKN_00369 1.7e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KIAEFMKN_00370 1.7e-252 E Amino acid permease
KIAEFMKN_00372 6e-224 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KIAEFMKN_00373 1.7e-232 amt P Ammonium transporter
KIAEFMKN_00374 9.9e-294 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KIAEFMKN_00375 1.6e-120 citT T response regulator
KIAEFMKN_00376 2.3e-238 citH C Citrate transporter
KIAEFMKN_00377 2.6e-183 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KIAEFMKN_00378 0.0 helD 3.6.4.12 L DNA helicase
KIAEFMKN_00381 2.2e-99 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KIAEFMKN_00382 1.4e-147 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KIAEFMKN_00383 1.2e-290 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KIAEFMKN_00384 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KIAEFMKN_00385 6.1e-214 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KIAEFMKN_00386 6.6e-122 K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KIAEFMKN_00388 3.6e-131 ric D Di-iron-containing protein involved in the repair of iron-sulfur clusters
KIAEFMKN_00389 6.4e-96 S Belongs to the UPF0312 family
KIAEFMKN_00390 1.1e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KIAEFMKN_00392 4.5e-191 T HD domain
KIAEFMKN_00393 8.6e-278 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
KIAEFMKN_00395 0.0 ydaO E amino acid
KIAEFMKN_00396 1.6e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KIAEFMKN_00397 3e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KIAEFMKN_00398 1.2e-172 ydbI S AI-2E family transporter
KIAEFMKN_00399 1.5e-132 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KIAEFMKN_00401 1.3e-135 glnH ET Belongs to the bacterial solute-binding protein 3 family
KIAEFMKN_00402 1.2e-109 gluC P ABC transporter
KIAEFMKN_00403 6.6e-117 glnP P ABC transporter
KIAEFMKN_00404 6.5e-69 K helix_turn_helix gluconate operon transcriptional repressor
KIAEFMKN_00405 2.2e-196 S Protein of unknown function (DUF1648)
KIAEFMKN_00406 3.7e-54 yodB K transcriptional
KIAEFMKN_00407 3.1e-234 S SNARE associated Golgi protein
KIAEFMKN_00408 4.2e-96 yngC S membrane-associated protein
KIAEFMKN_00409 6.6e-160 msrR K COG1316 Transcriptional regulator
KIAEFMKN_00410 1.2e-198 L COG3039 Transposase and inactivated derivatives, IS5 family
KIAEFMKN_00411 1.4e-198 L COG3039 Transposase and inactivated derivatives, IS5 family
KIAEFMKN_00412 7.5e-199 L COG3039 Transposase and inactivated derivatives, IS5 family
KIAEFMKN_00413 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KIAEFMKN_00414 0.0 metH 2.1.1.13 E Methionine synthase
KIAEFMKN_00415 3.4e-12 csbD S Belongs to the UPF0337 (CsbD) family
KIAEFMKN_00416 4.8e-87 K ComK protein
KIAEFMKN_00417 1.1e-101 sigS 2.7.7.6 K Belongs to the sigma-70 factor family. ECF subfamily
KIAEFMKN_00418 2.2e-148 E lipolytic protein G-D-S-L family
KIAEFMKN_00419 9.7e-119 ywqC M biosynthesis protein
KIAEFMKN_00420 1.5e-108 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KIAEFMKN_00421 1.8e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KIAEFMKN_00422 6.4e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KIAEFMKN_00423 3.7e-88 cpsE M Bacterial sugar transferase
KIAEFMKN_00424 3.2e-18 GT2 M Glycosyltransferase like family 2
KIAEFMKN_00425 1.2e-89 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KIAEFMKN_00426 1.7e-152 rgpAc GT4 M Domain of unknown function (DUF1972)
KIAEFMKN_00427 5.4e-126 S polysaccharide biosynthetic process
KIAEFMKN_00428 7.4e-104 G Glycosyl transferases group 1
KIAEFMKN_00429 3.2e-61
KIAEFMKN_00430 6.9e-148 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KIAEFMKN_00431 2e-87 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KIAEFMKN_00432 8e-133 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KIAEFMKN_00433 3.5e-183 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KIAEFMKN_00434 1.2e-142 D nuclear chromosome segregation
KIAEFMKN_00435 0.0 L Domain of unknown function (DUF4277)
KIAEFMKN_00436 6.4e-117 xylR GK Transcriptional regulator
KIAEFMKN_00437 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
KIAEFMKN_00438 1.4e-198 xylP G COGs COG2211 Na melibiose symporter and related transporter
KIAEFMKN_00439 1.3e-259 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KIAEFMKN_00440 9.3e-286 xylB 2.7.1.12, 2.7.1.17 G xylulose kinase
KIAEFMKN_00441 0.0 M Non-essential cell division protein that could be required for efficient cell constriction
KIAEFMKN_00442 1.8e-248 L PFAM Transposase, IS4-like
KIAEFMKN_00443 1.7e-134 M Non-essential cell division protein that could be required for efficient cell constriction
KIAEFMKN_00444 3.2e-59 croE S Helix-turn-helix
KIAEFMKN_00445 3.5e-135 E IrrE N-terminal-like domain
KIAEFMKN_00446 1.9e-38
KIAEFMKN_00447 8.4e-246 yicJ G MFS/sugar transport protein
KIAEFMKN_00448 3.3e-302 2.7.1.12, 2.7.1.17 G xylulose kinase
KIAEFMKN_00449 2.5e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIAEFMKN_00450 8.1e-210 2.7.1.2 GK ROK family
KIAEFMKN_00451 1.1e-29 L DDE superfamily endonuclease
KIAEFMKN_00452 1.1e-155 L DDE superfamily endonuclease
KIAEFMKN_00453 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KIAEFMKN_00454 3.3e-72 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KIAEFMKN_00455 2.1e-179 3.1.1.5 I Alpha beta hydrolase
KIAEFMKN_00457 0.0 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KIAEFMKN_00459 1.9e-29 yodI
KIAEFMKN_00460 7e-152 yjaZ O Zn-dependent protease
KIAEFMKN_00461 3.3e-132 yodH Q Methyltransferase
KIAEFMKN_00462 5.3e-122 S PD-(D/E)XK nuclease family transposase
KIAEFMKN_00463 9.3e-74 2.1.1.113 L N-4 methylation of cytosine
KIAEFMKN_00464 2.6e-110 S Protein of unknown function DUF262
KIAEFMKN_00465 3.5e-41
KIAEFMKN_00466 1.6e-54 L Transposase
KIAEFMKN_00467 3.1e-32 gtfC 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KIAEFMKN_00468 4.8e-70 G PTS system fructose IIA component
KIAEFMKN_00469 4.3e-147 G PTS system mannose/fructose/sorbose family IID component
KIAEFMKN_00470 2.8e-140 agaC G PTS system sorbose-specific iic component
KIAEFMKN_00471 3.9e-81 agaB 2.7.1.191 G PTS system sorbose subfamily IIB component
KIAEFMKN_00472 6.6e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KIAEFMKN_00473 1.4e-130 K UTRA
KIAEFMKN_00474 5.9e-97 puuR_2 K Cupin domain
KIAEFMKN_00475 0.0 oplaH 3.5.2.14, 3.5.2.9 EQ COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit
KIAEFMKN_00476 0.0 3.5.2.14 EQ COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit
KIAEFMKN_00477 3.7e-257 F Permease for cytosine/purines, uracil, thiamine, allantoin
KIAEFMKN_00478 0.0 K PTS system fructose IIA component
KIAEFMKN_00479 2e-71 2.7.1.191 G PTS system fructose IIA component
KIAEFMKN_00480 3.4e-80 2.7.1.191 G PTS system mannose fructose sorbose family
KIAEFMKN_00481 1.5e-133 G PTS system sorbose-specific iic component
KIAEFMKN_00482 1.4e-142 G PFAM Phosphotransferase system, mannose fructose sorbose family IID component
KIAEFMKN_00483 2.8e-196 M SIS domain
KIAEFMKN_00484 8.1e-162 S peptidyl-serine autophosphorylation
KIAEFMKN_00485 1.2e-145 S HIRAN
KIAEFMKN_00486 5.4e-55 S YfzA-like protein
KIAEFMKN_00487 2.4e-105 S ABC-2 family transporter protein
KIAEFMKN_00488 1.8e-143 V ABC transporter
KIAEFMKN_00489 1.6e-302 K COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KIAEFMKN_00490 5.8e-200 S Protein of unknown function (DUF917)
KIAEFMKN_00491 1.3e-282 apc3 3.5.2.9 EQ Hydantoinase oxoprolinase
KIAEFMKN_00492 6.6e-211 codB F cytosine purines uracil thiamine allantoin
KIAEFMKN_00493 2.1e-202 S Protein of unknown function (DUF917)
KIAEFMKN_00494 8.5e-290 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase
KIAEFMKN_00495 6.9e-181 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KIAEFMKN_00496 6.4e-68 yjbR S YjbR
KIAEFMKN_00497 7.6e-52 S Protein of unknown function (DUF1648)
KIAEFMKN_00498 3.2e-08 S Protein of unknown function (DUF1648)
KIAEFMKN_00499 2.5e-250 L Metallo-beta-lactamase superfamily
KIAEFMKN_00500 1.4e-30 S Protein of unknown function (DUF3006)
KIAEFMKN_00501 0.0 ganB 3.2.1.89 G arabinogalactan
KIAEFMKN_00502 4e-240 L Transposase DDE domain group 1
KIAEFMKN_00503 0.0 ybeC E amino acid
KIAEFMKN_00504 5.4e-09 3.2.1.78 GH26 O cellulase activity
KIAEFMKN_00505 0.0 L Domain of unknown function (DUF4277)
KIAEFMKN_00506 0.0 3.2.1.78 GH26 O cellulase activity
KIAEFMKN_00507 1.1e-178 K cell envelope-related transcriptional attenuator
KIAEFMKN_00508 9.5e-51
KIAEFMKN_00510 5e-173 ydhF S Oxidoreductase
KIAEFMKN_00511 1.7e-141 S transposase or invertase
KIAEFMKN_00513 1.2e-52 S Domain of unknown function (DUF3870)
KIAEFMKN_00514 3.5e-235 B4168_2380 1.3.99.32 I Acyl-CoA dehydrogenase, N-terminal domain
KIAEFMKN_00515 1e-223 C acyl-CoA transferases carnitine dehydratase
KIAEFMKN_00516 2.9e-190 yfmJ S N-terminal domain of oxidoreductase
KIAEFMKN_00517 3.1e-215 EGP Major facilitator Superfamily
KIAEFMKN_00518 0.0 2.7.1.202 K transcriptional regulator, MtlR
KIAEFMKN_00519 8.7e-51 licB 2.7.1.196, 2.7.1.205 G phosphotransferase system
KIAEFMKN_00520 1.9e-50 chbA 2.7.1.196, 2.7.1.205 G PTS cellobiose transporter subunit IIA
KIAEFMKN_00521 1.9e-208 S Bacterial protein of unknown function (DUF871)
KIAEFMKN_00522 1e-232 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIAEFMKN_00523 3e-254 gph G MFS/sugar transport protein
KIAEFMKN_00525 6.3e-252 E Amino acid permease
KIAEFMKN_00526 0.0 K helix_turn_helix, arabinose operon control protein
KIAEFMKN_00527 1e-223 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KIAEFMKN_00528 4.6e-185 tdh 4.2.1.45 GM GDP-mannose 4,6 dehydratase
KIAEFMKN_00529 8.5e-75 K transcriptional
KIAEFMKN_00530 2.4e-207 EGP Major facilitator Superfamily
KIAEFMKN_00531 1.3e-174 K Transcriptional regulator
KIAEFMKN_00533 0.0 bga2 3.2.1.23 G beta-galactosidase
KIAEFMKN_00534 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KIAEFMKN_00535 1.1e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KIAEFMKN_00536 3.4e-115 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KIAEFMKN_00537 2.2e-210 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KIAEFMKN_00538 4.5e-97 yvbF K Belongs to the GbsR family
KIAEFMKN_00539 1e-96 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
KIAEFMKN_00540 3.6e-191 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KIAEFMKN_00541 3.2e-46
KIAEFMKN_00542 7.5e-111 yjlB S Cupin domain
KIAEFMKN_00543 3.1e-150 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
KIAEFMKN_00544 2e-137 yflN_1 S Metallo-beta-lactamase superfamily
KIAEFMKN_00545 8.8e-297 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KIAEFMKN_00546 1.4e-303 comM O Mg chelatase subunit ChlI
KIAEFMKN_00547 1.2e-148 S transposase or invertase
KIAEFMKN_00548 6.7e-20
KIAEFMKN_00549 2.1e-199 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KIAEFMKN_00550 2.4e-248 csbC EGP Major facilitator Superfamily
KIAEFMKN_00551 1.2e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
KIAEFMKN_00552 1.7e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KIAEFMKN_00553 7.2e-217 xylR GK ROK family
KIAEFMKN_00554 4.8e-207 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KIAEFMKN_00555 5.9e-152 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KIAEFMKN_00556 2.4e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KIAEFMKN_00557 2.1e-205 nifS 2.8.1.7 E Cysteine desulfurase
KIAEFMKN_00558 3.2e-95 S NYN domain
KIAEFMKN_00559 1.2e-143 focA P Formate nitrite
KIAEFMKN_00560 3.7e-264 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KIAEFMKN_00561 2.6e-144 cbiQ P COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
KIAEFMKN_00562 0.0 ykoD P ABC transporter, ATP-binding protein
KIAEFMKN_00563 2e-92 S UPF0397 protein
KIAEFMKN_00564 1.1e-163 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KIAEFMKN_00565 1.5e-122 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KIAEFMKN_00566 6.4e-252 EG COG2610 H gluconate symporter and related permeases
KIAEFMKN_00567 1.4e-283 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KIAEFMKN_00568 7.8e-219 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
KIAEFMKN_00569 0.0 KT Transcriptional regulator
KIAEFMKN_00570 0.0 xylS 3.2.1.20 GH31 G Domain of unknown function (DUF5110)
KIAEFMKN_00571 6.6e-16 xylS 3.2.1.20 GH31 G Domain of unknown function (DUF5110)
KIAEFMKN_00572 6.1e-281 Otg1 S Predicted membrane protein (DUF2339)
KIAEFMKN_00573 2.1e-229 1.3.8.7 I Acyl-CoA dehydrogenase, N-terminal domain
KIAEFMKN_00574 9.6e-283 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KIAEFMKN_00575 3.8e-195 S Metallo-beta-lactamase superfamily
KIAEFMKN_00576 2.2e-26 K Bacterial regulatory proteins, tetR family
KIAEFMKN_00577 3.8e-26 K Bacterial regulatory proteins, tetR family
KIAEFMKN_00578 0.0 fldZ 1.3.1.31 C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KIAEFMKN_00579 5.3e-12 S PFAM Uncharacterised protein family UPF0236
KIAEFMKN_00580 2.1e-207 ysdC G COG1363 Cellulase M and related proteins
KIAEFMKN_00582 1.2e-43
KIAEFMKN_00583 6.2e-52 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KIAEFMKN_00584 1.6e-108
KIAEFMKN_00585 4.2e-43
KIAEFMKN_00587 3.9e-47 S double-stranded DNA endodeoxyribonuclease activity
KIAEFMKN_00588 2.1e-13 S double-stranded DNA endodeoxyribonuclease activity
KIAEFMKN_00589 2.6e-132 VVA0018 T Histidine kinase
KIAEFMKN_00590 2e-129 T helix_turn_helix, arabinose operon control protein
KIAEFMKN_00591 9.7e-08 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KIAEFMKN_00592 5.1e-170 3.5.1.4 C Acetamidase
KIAEFMKN_00593 2.9e-225 puuP_1 E Amino acid permease
KIAEFMKN_00594 2.3e-21 S Zinc-ribbon containing domain
KIAEFMKN_00595 1.4e-298 yvfH C L-lactate permease
KIAEFMKN_00596 1.1e-122 yvfI K COG2186 Transcriptional regulators
KIAEFMKN_00597 1.3e-226 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KIAEFMKN_00598 7.3e-59
KIAEFMKN_00600 1.3e-168 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KIAEFMKN_00601 1.6e-219 EGP Major facilitator Superfamily
KIAEFMKN_00602 3.5e-133 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KIAEFMKN_00603 4.7e-38 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KIAEFMKN_00604 2.2e-16 S YvrJ protein family
KIAEFMKN_00605 9.8e-11 S Protein of unknown function (DUF2922)
KIAEFMKN_00606 5.8e-11 S Protein of unknown function (DUF1659)
KIAEFMKN_00607 0.0 O Belongs to the peptidase S8 family
KIAEFMKN_00608 3.9e-69 S Protein of unknown function (DUF2512)
KIAEFMKN_00609 9.4e-50 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KIAEFMKN_00610 7.6e-52 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
KIAEFMKN_00611 1.9e-81
KIAEFMKN_00612 8.2e-249 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIAEFMKN_00613 4.1e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KIAEFMKN_00614 0.0 2.7.1.202 K transcriptional regulator, MtlR
KIAEFMKN_00615 5.6e-22 L Domain of unknown function (DUF4277)
KIAEFMKN_00616 1e-265 L Domain of unknown function (DUF4277)
KIAEFMKN_00617 1e-156 kdsA 2.5.1.55 M Belongs to the KdsA family
KIAEFMKN_00618 1.8e-176 kdsD 5.3.1.13 M Belongs to the SIS family. GutQ KpsF subfamily
KIAEFMKN_00619 4.6e-163 V ATPases associated with a variety of cellular activities
KIAEFMKN_00620 2.2e-08
KIAEFMKN_00621 1.7e-229 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KIAEFMKN_00622 1.9e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KIAEFMKN_00623 0.0 treP 2.4.1.64 GH65 G Glycoside hydrolase, family 65
KIAEFMKN_00624 5.5e-147 G Binding-protein-dependent transport system inner membrane component
KIAEFMKN_00625 6.5e-221 sugA G Binding-protein-dependent transport system inner membrane component
KIAEFMKN_00626 1.7e-224 G Bacterial extracellular solute-binding protein
KIAEFMKN_00627 2e-132 K helix_turn_helix, arabinose operon control protein
KIAEFMKN_00628 1.7e-62 S Region found in RelA / SpoT proteins
KIAEFMKN_00629 1.8e-08
KIAEFMKN_00630 2e-137 gumM 2.4.1.187, 2.4.1.252 GT26,GT4 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KIAEFMKN_00631 2.7e-23 S Iron-sulphur cluster biosynthesis
KIAEFMKN_00632 1.9e-15 S Ribbon-helix-helix protein, copG family
KIAEFMKN_00633 1.9e-211 L Transposase
KIAEFMKN_00634 5.7e-175 yhfP 1.1.1.1 C Quinone oxidoreductase
KIAEFMKN_00635 3.9e-159 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KIAEFMKN_00636 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KIAEFMKN_00637 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
KIAEFMKN_00638 3e-84
KIAEFMKN_00639 5.4e-147 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KIAEFMKN_00641 2.9e-131 IQ Short-chain dehydrogenase reductase sdr
KIAEFMKN_00642 3e-28 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KIAEFMKN_00643 5.2e-110 cyoC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KIAEFMKN_00644 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KIAEFMKN_00645 1e-157 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KIAEFMKN_00646 1.5e-123 yhcW 5.4.2.6 S hydrolase
KIAEFMKN_00647 3.4e-166 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KIAEFMKN_00648 2.6e-20
KIAEFMKN_00649 0.0 ppc 4.1.1.31 C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KIAEFMKN_00651 2.9e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KIAEFMKN_00652 2e-73 yabE S 3D domain
KIAEFMKN_00653 1.9e-255 L PFAM Transposase, IS4-like
KIAEFMKN_00655 4.2e-162 expZ S ABC transporter
KIAEFMKN_00656 2.7e-94 relA_2 2.7.6.5, 3.1.7.2 KT HD domain
KIAEFMKN_00657 0.0 pip S YhgE Pip N-terminal domain protein
KIAEFMKN_00658 1.4e-47 yqgV S Thiamine-binding protein
KIAEFMKN_00659 4.6e-199 pgl 3.1.1.31 G 6-phosphogluconolactonase
KIAEFMKN_00660 0.0 S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KIAEFMKN_00661 0.0 levR K PTS system fructose IIA component
KIAEFMKN_00662 2.4e-84 manX 2.7.1.191 G PTS system sorbose subfamily IIB component
KIAEFMKN_00663 2.4e-178 manL 2.7.1.191 G PTS system mannose fructose sorbose family
KIAEFMKN_00664 4.8e-119 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KIAEFMKN_00665 1.9e-169 manN G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KIAEFMKN_00666 9.1e-65 manO S Domain of unknown function (DUF956)
KIAEFMKN_00667 1.1e-211 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KIAEFMKN_00668 2.7e-282 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KIAEFMKN_00669 2.5e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KIAEFMKN_00670 1.2e-80 S Heat induced stress protein YflT
KIAEFMKN_00671 5.1e-276 nylA 3.5.1.4 J Belongs to the amidase family
KIAEFMKN_00673 4.5e-120 M1-594 S Thiamine-binding protein
KIAEFMKN_00674 1.3e-140 ssuC_1 P binding-protein-dependent transport systems inner membrane component
KIAEFMKN_00675 2.1e-185 M1-596 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KIAEFMKN_00676 1.6e-140 P ABC transporter, ATP-binding protein
KIAEFMKN_00677 4.2e-164 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KIAEFMKN_00678 6.3e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KIAEFMKN_00679 8.4e-243 hom 1.1.1.3 E homoserine dehydrogenase
KIAEFMKN_00680 9.8e-146 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KIAEFMKN_00681 1.5e-17 S Protein of unknown function (DUF4064)
KIAEFMKN_00682 6.2e-290 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KIAEFMKN_00683 5.7e-166 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KIAEFMKN_00684 3.1e-46 yhdT S Sodium pantothenate symporter
KIAEFMKN_00685 1.2e-234 panF H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KIAEFMKN_00688 4.8e-171 corA P Mg2 transporter protein CorA family protein
KIAEFMKN_00689 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KIAEFMKN_00690 3.7e-268 S PFAM Uncharacterised protein family UPF0236
KIAEFMKN_00691 3.3e-211 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KIAEFMKN_00692 7e-77
KIAEFMKN_00693 1.1e-77 lytE CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KIAEFMKN_00694 1.3e-139 map 3.4.11.18 E Methionine aminopeptidase
KIAEFMKN_00696 1.4e-99 bioY S Biotin biosynthesis protein
KIAEFMKN_00697 2.3e-63 cueR K transcriptional
KIAEFMKN_00698 2.2e-295 6.2.1.3, 6.2.1.34 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KIAEFMKN_00699 0.0 aidB I Acyl-CoA dehydrogenase, middle domain
KIAEFMKN_00700 1.7e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIAEFMKN_00701 2.3e-153 aacC 2.3.1.81 V aminoglycoside
KIAEFMKN_00702 1.3e-214 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KIAEFMKN_00703 2.1e-70 yxiE T Belongs to the universal stress protein A family
KIAEFMKN_00704 8.4e-28
KIAEFMKN_00705 1.5e-69
KIAEFMKN_00706 6.3e-226 yfkA S YfkB-like domain
KIAEFMKN_00708 7e-286 K NB-ARC domain
KIAEFMKN_00709 1.3e-201 gutB 1.1.1.14 E Dehydrogenase
KIAEFMKN_00710 1.4e-190 gutA G MFS/sugar transport protein
KIAEFMKN_00711 1.4e-181 ykvZ 5.1.1.1 K Transcriptional regulator
KIAEFMKN_00712 5.1e-93 hxlB 4.1.2.43, 5.3.1.27 M arabinose-5-phosphate isomerase activity
KIAEFMKN_00713 4e-147 ykrA S hydrolases of the HAD superfamily
KIAEFMKN_00715 1e-147 yvaK 3.1.1.1 S BAAT / Acyl-CoA thioester hydrolase C terminal
KIAEFMKN_00716 0.0 ubiE2 Q Methyltransferase domain
KIAEFMKN_00717 3e-113 M Spore coat protein
KIAEFMKN_00718 5.7e-135 I alpha/beta hydrolase fold
KIAEFMKN_00719 6e-154 S Aldo/keto reductase family
KIAEFMKN_00720 3.6e-97 1.5.1.38 S FMN reductase
KIAEFMKN_00721 1.9e-247 yhaO L Calcineurin-like phosphoesterase superfamily domain
KIAEFMKN_00722 0.0 L AAA domain
KIAEFMKN_00723 2.7e-152 mmgB 1.1.1.157 I Dehydrogenase
KIAEFMKN_00724 7.9e-247 yeeO V Mate efflux family protein
KIAEFMKN_00725 5.5e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
KIAEFMKN_00726 1.8e-53 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KIAEFMKN_00727 1.8e-110 yhbD K Protein of unknown function (DUF4004)
KIAEFMKN_00728 7.9e-224 yhdR 2.6.1.1 E Aminotransferase
KIAEFMKN_00729 4.3e-104 proA_2 H Methyltransferase
KIAEFMKN_00730 0.0 rafA 3.2.1.22 G Alpha-galactosidase
KIAEFMKN_00731 2.3e-51 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIAEFMKN_00732 5.6e-269 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KIAEFMKN_00733 3.4e-146 ubiE Q Methyltransferase type 11
KIAEFMKN_00734 7.8e-39
KIAEFMKN_00735 2.2e-170 S Acetyl xylan esterase (AXE1)
KIAEFMKN_00736 8.8e-147 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KIAEFMKN_00737 2.7e-86 thiW S Thiamine-precursor transporter protein (ThiW)
KIAEFMKN_00738 3.2e-272 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KIAEFMKN_00739 6.4e-260 pucI FH Permease for cytosine/purines, uracil, thiamine, allantoin
KIAEFMKN_00740 2.1e-79 yjhE S Phage tail protein
KIAEFMKN_00741 2e-140 2.7.1.202 GKT transcriptional antiterminator
KIAEFMKN_00742 6e-35 ulaB 2.7.1.194 G COG3414 Phosphotransferase system, galactitol-specific IIB component
KIAEFMKN_00743 3.3e-205 ulaA 2.7.1.194 S PTS system sugar-specific permease component
KIAEFMKN_00745 1e-259 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KIAEFMKN_00746 2.8e-252 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KIAEFMKN_00747 1e-271 EGP Major facilitator Superfamily
KIAEFMKN_00748 5.1e-108 K Bacterial regulatory proteins, tetR family
KIAEFMKN_00749 9.7e-183 ydgH S drug exporters of the RND superfamily
KIAEFMKN_00750 6.4e-145 hel M 5'-nucleotidase, lipoprotein e(P4)
KIAEFMKN_00753 7.2e-214 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KIAEFMKN_00754 2.5e-17 I acyl-CoA dehydrogenase activity
KIAEFMKN_00755 1.1e-12
KIAEFMKN_00756 2.1e-224 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KIAEFMKN_00757 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KIAEFMKN_00758 8e-282 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KIAEFMKN_00759 6.6e-198 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
KIAEFMKN_00760 5.7e-183 K Transcriptional regulator
KIAEFMKN_00761 5.1e-32 S Cold-inducible protein YdjO
KIAEFMKN_00762 1.5e-14
KIAEFMKN_00764 1e-164 cvfB S protein conserved in bacteria
KIAEFMKN_00765 4.4e-70 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KIAEFMKN_00766 4.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
KIAEFMKN_00767 1.6e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KIAEFMKN_00769 9.8e-272 yusP P Major facilitator superfamily
KIAEFMKN_00770 9.8e-211 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KIAEFMKN_00771 5.2e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KIAEFMKN_00772 5.6e-124 gntR1 K transcriptional
KIAEFMKN_00773 1.8e-181 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KIAEFMKN_00774 8.8e-228 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KIAEFMKN_00775 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KIAEFMKN_00776 2.7e-167 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KIAEFMKN_00777 7.3e-115 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KIAEFMKN_00778 5.8e-203 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KIAEFMKN_00779 2.4e-124 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KIAEFMKN_00780 1.4e-259 yfnA E amino acid
KIAEFMKN_00781 3.1e-153 degV S protein conserved in bacteria
KIAEFMKN_00782 7.6e-258 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KIAEFMKN_00783 4.9e-128 comFC S Phosphoribosyl transferase domain
KIAEFMKN_00784 4.4e-70 yvyF S flagellar protein
KIAEFMKN_00785 1.8e-38 flgM KNU Negative regulator of flagellin synthesis
KIAEFMKN_00786 5.5e-75 flgN NOU FlgN protein
KIAEFMKN_00787 5.5e-292 flgK N flagellar hook-associated protein
KIAEFMKN_00788 5.2e-159 flgL N Belongs to the bacterial flagellin family
KIAEFMKN_00789 9.2e-80 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KIAEFMKN_00790 3.5e-15 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KIAEFMKN_00791 8.8e-248 L PFAM Transposase, IS4-like
KIAEFMKN_00792 7.9e-09 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KIAEFMKN_00793 9e-98 secA U SEC-C motif
KIAEFMKN_00794 3e-84 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KIAEFMKN_00795 6.7e-259 L Transposase
KIAEFMKN_00796 1.7e-22
KIAEFMKN_00797 1.4e-12 K Glycerol-3-phosphate responsive antiterminator
KIAEFMKN_00798 2.5e-16 K Glycerol-3-phosphate responsive antiterminator
KIAEFMKN_00800 6.9e-82 sapB S MgtC SapB transporter
KIAEFMKN_00801 3.5e-200 EGP Sugar (and other) transporter
KIAEFMKN_00803 1.5e-176 E COG1113 Gamma-aminobutyrate permease and related permeases
KIAEFMKN_00805 0.0 ycbZ 3.4.21.53 O AAA domain
KIAEFMKN_00807 3.3e-109 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KIAEFMKN_00809 5.1e-60 flaG N flagellar protein FlaG
KIAEFMKN_00810 3.4e-225 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KIAEFMKN_00811 8.6e-69 fliS N flagellar protein FliS
KIAEFMKN_00812 1.1e-56 fliT S bacterial-type flagellum organization
KIAEFMKN_00813 2.7e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KIAEFMKN_00814 2.1e-299 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KIAEFMKN_00815 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KIAEFMKN_00816 2.5e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KIAEFMKN_00817 3.6e-157 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KIAEFMKN_00818 2.9e-51 cccB C COG2010 Cytochrome c, mono- and diheme variants
KIAEFMKN_00820 3e-122 ftsE D cell division ATP-binding protein FtsE
KIAEFMKN_00821 1.4e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KIAEFMKN_00822 4.8e-92 D peptidase
KIAEFMKN_00823 9.3e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KIAEFMKN_00824 1.3e-248 metY 2.5.1.49 E O-acetylhomoserine
KIAEFMKN_00825 3.7e-182 1.1.1.3 E homoserine dehydrogenase
KIAEFMKN_00826 7.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KIAEFMKN_00827 4.4e-222 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KIAEFMKN_00828 3.6e-166 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIAEFMKN_00829 1.8e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIAEFMKN_00830 3.6e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KIAEFMKN_00831 1.1e-178 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KIAEFMKN_00832 2.1e-41 fdxA C 4Fe-4S binding domain
KIAEFMKN_00833 4.5e-46 S Family of unknown function (DUF5316)
KIAEFMKN_00834 1.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIAEFMKN_00835 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KIAEFMKN_00836 1.2e-20 phoR 2.7.13.3 T Signal transduction histidine kinase
KIAEFMKN_00837 1.8e-262 hemY2 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KIAEFMKN_00838 3.2e-161 pstS P Phosphate
KIAEFMKN_00839 8.3e-163 pstC P probably responsible for the translocation of the substrate across the membrane
KIAEFMKN_00840 8.2e-157 pstA P Phosphate transport system permease
KIAEFMKN_00841 4.4e-152 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KIAEFMKN_00842 4.4e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KIAEFMKN_00843 1.4e-118 yfbR S HD containing hydrolase-like enzyme
KIAEFMKN_00844 2.4e-34 csbA S protein conserved in bacteria
KIAEFMKN_00845 5.5e-10 S Uncharacterized conserved protein (DUF2164)
KIAEFMKN_00846 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KIAEFMKN_00847 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KIAEFMKN_00848 2.8e-72 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KIAEFMKN_00849 9.8e-230 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KIAEFMKN_00850 3.6e-145 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KIAEFMKN_00851 1e-168 M Dolichyl-phosphate-mannose-protein mannosyltransferase
KIAEFMKN_00852 3.1e-231 tagF 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KIAEFMKN_00853 0.0 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KIAEFMKN_00854 5e-145 tagG GM Transport permease protein
KIAEFMKN_00855 2.6e-230 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KIAEFMKN_00856 3.9e-159 yvlB S Putative adhesin
KIAEFMKN_00857 1.2e-31 yvlD S Membrane
KIAEFMKN_00858 5.7e-172 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KIAEFMKN_00859 3.9e-153 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KIAEFMKN_00860 4.9e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KIAEFMKN_00861 1.6e-72 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KIAEFMKN_00862 3.8e-255 S COG0457 FOG TPR repeat
KIAEFMKN_00863 3.1e-178 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KIAEFMKN_00864 3e-86 yvcI 3.6.1.55 F Nudix hydrolase
KIAEFMKN_00865 8.8e-167 rapZ S Displays ATPase and GTPase activities
KIAEFMKN_00866 6.9e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KIAEFMKN_00867 1.1e-172 whiA K May be required for sporulation
KIAEFMKN_00868 4.3e-40 crh G Phosphocarrier protein Chr
KIAEFMKN_00869 2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KIAEFMKN_00871 5.5e-148 S transposase or invertase
KIAEFMKN_00872 1.8e-14 S transposase or invertase
KIAEFMKN_00873 1.3e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KIAEFMKN_00874 3.4e-29 sspB S spore protein
KIAEFMKN_00875 6.9e-206 msmK P Belongs to the ABC transporter superfamily
KIAEFMKN_00876 2.3e-159 lrp QT PucR C-terminal helix-turn-helix domain
KIAEFMKN_00877 8.2e-229 HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
KIAEFMKN_00878 3.2e-269 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KIAEFMKN_00879 1.3e-212 yheC HJ YheC/D like ATP-grasp
KIAEFMKN_00880 2.6e-255 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KIAEFMKN_00881 2e-208 yheB S Belongs to the UPF0754 family
KIAEFMKN_00882 5.1e-54 yheA S Belongs to the UPF0342 family
KIAEFMKN_00883 3.2e-161 yhaX S hydrolases of the HAD superfamily
KIAEFMKN_00884 5.2e-139 yhaR 5.3.3.18 I enoyl-CoA hydratase
KIAEFMKN_00885 2.9e-27 S YhzD-like protein
KIAEFMKN_00886 1.8e-123 P Integral membrane protein TerC family
KIAEFMKN_00888 1.6e-158 ycgR S permeases
KIAEFMKN_00889 1e-164 ycgQ S membrane
KIAEFMKN_00890 2.8e-240 yhaO L DNA repair exonuclease
KIAEFMKN_00891 0.0 L AAA domain
KIAEFMKN_00892 3.7e-179 yhaM L Shows a 3'-5' exoribonuclease activity
KIAEFMKN_00893 3e-27 yhaL S Sporulation protein YhaL
KIAEFMKN_00894 6.2e-149 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KIAEFMKN_00896 3.7e-54 yhaI S Protein of unknown function (DUF1878)
KIAEFMKN_00897 2e-103 hpr K Negative regulator of protease production and sporulation
KIAEFMKN_00898 1.6e-18 yhaH S YtxH-like protein
KIAEFMKN_00900 6.5e-85 trpP S Tryptophan transporter TrpP
KIAEFMKN_00901 1.4e-74 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KIAEFMKN_00902 2.5e-138 ecsA V transporter (ATP-binding protein)
KIAEFMKN_00903 1.6e-219 ecsB U ABC transporter
KIAEFMKN_00904 1.8e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KIAEFMKN_00905 1.4e-238 yhfA C membrane
KIAEFMKN_00906 2e-94 traP 1.14.99.57 S enzyme involved in biosynthesis of extracellular polysaccharides
KIAEFMKN_00907 3.6e-199 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KIAEFMKN_00908 1.2e-182 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KIAEFMKN_00909 1.5e-269 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KIAEFMKN_00910 7.1e-101 yhgD K Transcriptional regulator
KIAEFMKN_00911 1.3e-160 yhgE S YhgE Pip N-terminal domain protein
KIAEFMKN_00912 4.3e-183 arbF1 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
KIAEFMKN_00913 1.4e-133 ydjF K DeoR C terminal sensor domain
KIAEFMKN_00914 5.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
KIAEFMKN_00915 4.3e-242 iolF EGP Major facilitator Superfamily
KIAEFMKN_00916 1.2e-164 EG EamA-like transporter family
KIAEFMKN_00917 2.8e-263 aldA 1.2.1.21, 1.2.1.22 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KIAEFMKN_00918 1.1e-101 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KIAEFMKN_00919 8.1e-64 ytkA S YtkA-like
KIAEFMKN_00920 3e-21 yhfH S YhfH-like protein
KIAEFMKN_00921 3.6e-185 lplJ 6.3.1.20 H Lipoate-protein ligase
KIAEFMKN_00922 3.4e-291 fadD 6.2.1.3 IQ Activates fatty acids by binding to coenzyme A
KIAEFMKN_00923 7.6e-121 azlC E AzlC protein
KIAEFMKN_00924 3.9e-42 azlD S branched-chain amino acid
KIAEFMKN_00925 4.7e-219 yhfN 3.4.24.84 O Peptidase M48
KIAEFMKN_00926 3.4e-09 S IDEAL
KIAEFMKN_00927 2.6e-97 comK K Competence transcription factor
KIAEFMKN_00928 1.7e-145 S Mitochondrial biogenesis AIM24
KIAEFMKN_00930 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KIAEFMKN_00931 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KIAEFMKN_00932 4.2e-30 gerPF S Spore germination protein gerPA/gerPF
KIAEFMKN_00933 3.6e-73 gerPE S Spore germination protein GerPE
KIAEFMKN_00934 2e-25 gerPD S Spore germination protein
KIAEFMKN_00935 1.8e-102 gerPC S Spore germination protein
KIAEFMKN_00936 1.6e-32 gerPA S Spore germination protein
KIAEFMKN_00937 5.1e-223 P Protein of unknown function (DUF418)
KIAEFMKN_00938 4e-164 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KIAEFMKN_00939 3.3e-59 yisL S UPF0344 protein
KIAEFMKN_00940 2.3e-104 yisN S Protein of unknown function (DUF2777)
KIAEFMKN_00941 4.1e-08 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIAEFMKN_00942 3.8e-159 yitS S protein conserved in bacteria
KIAEFMKN_00943 2.2e-25 S Protein of unknown function (DUF3813)
KIAEFMKN_00944 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KIAEFMKN_00945 9.5e-52 yitW S metal-sulfur cluster biosynthetic enzyme
KIAEFMKN_00946 6.2e-27 yjzC S YjzC-like protein
KIAEFMKN_00947 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KIAEFMKN_00949 4.6e-148 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
KIAEFMKN_00951 3.3e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KIAEFMKN_00952 7.3e-236 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KIAEFMKN_00953 6.4e-153 yjaZ O Zn-dependent protease
KIAEFMKN_00954 2.2e-193 oppD P Belongs to the ABC transporter superfamily
KIAEFMKN_00955 1.3e-176 oppF P Belongs to the ABC transporter superfamily
KIAEFMKN_00956 3.9e-168 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIAEFMKN_00957 1.3e-133 oppC EP binding-protein-dependent transport systems inner membrane component
KIAEFMKN_00958 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
KIAEFMKN_00959 2.9e-147 yjbA S Belongs to the UPF0736 family
KIAEFMKN_00960 1e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KIAEFMKN_00961 4.5e-47 S Domain of unknown function (DUF3899)
KIAEFMKN_00962 1.5e-308 dppE_1 E ABC transporter substrate-binding protein
KIAEFMKN_00963 1.2e-153 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIAEFMKN_00964 1.1e-184 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIAEFMKN_00965 5.7e-197 oppD P Belongs to the ABC transporter superfamily
KIAEFMKN_00966 2.9e-176 oppF E Belongs to the ABC transporter superfamily
KIAEFMKN_00967 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KIAEFMKN_00968 7.1e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KIAEFMKN_00969 6.1e-235 yjbF S Competence protein
KIAEFMKN_00970 0.0 pepF E oligoendopeptidase F
KIAEFMKN_00972 2.6e-160 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KIAEFMKN_00973 1.4e-74 yjbI S COG2346 Truncated hemoglobins
KIAEFMKN_00974 6.7e-78 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KIAEFMKN_00975 1.3e-102 yjbK S protein conserved in bacteria
KIAEFMKN_00976 1.9e-65 yjbL S Belongs to the UPF0738 family
KIAEFMKN_00977 9.4e-121 yjbM 2.7.6.5 S GTP pyrophosphokinase
KIAEFMKN_00978 4.9e-153 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KIAEFMKN_00979 4.4e-163 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KIAEFMKN_00980 3.6e-142 prpE 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KIAEFMKN_00981 1.9e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KIAEFMKN_00984 1.2e-84 cotY S Spore coat protein
KIAEFMKN_00985 1.7e-57 S Protein of unknown function (DUF1360)
KIAEFMKN_00987 2.5e-80 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KIAEFMKN_00988 7.2e-83 spoVAC S stage V sporulation protein AC
KIAEFMKN_00989 2.2e-190 spoVAD I Stage V sporulation protein AD
KIAEFMKN_00990 8.7e-57 spoVAE S stage V sporulation protein
KIAEFMKN_00992 1e-198 L COG3039 Transposase and inactivated derivatives, IS5 family
KIAEFMKN_00993 1.7e-178 tnp4 L Transposase, Mutator family
KIAEFMKN_00994 4.5e-39 spoVIF S Stage VI sporulation protein F
KIAEFMKN_00996 3.8e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KIAEFMKN_00997 1.5e-94 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KIAEFMKN_00998 1.8e-141 yjcH P COG2382 Enterochelin esterase and related enzymes
KIAEFMKN_01007 4.9e-32 ydhM 2.7.1.196, 2.7.1.205 G Phosphotransferase System
KIAEFMKN_01008 5.3e-205 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIAEFMKN_01009 4.7e-35 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
KIAEFMKN_01010 1.3e-236 ydhP 3.2.1.21, 3.2.1.86 GT1 G Glycosyl hydrolase family 1
KIAEFMKN_01011 2.5e-90 ydhQ K GntR family
KIAEFMKN_01012 7.1e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KIAEFMKN_01013 6.9e-56
KIAEFMKN_01014 1.3e-131 IQ Enoyl-(Acyl carrier protein) reductase
KIAEFMKN_01015 2.1e-168 yhaQ S ABC transporter, ATP-binding protein
KIAEFMKN_01016 3e-213 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KIAEFMKN_01017 2.4e-261 pepC 3.4.22.40 E Papain family cysteine protease
KIAEFMKN_01018 2.3e-221 EGP Major facilitator Superfamily
KIAEFMKN_01019 0.0 pepF2 E COG1164 Oligoendopeptidase F
KIAEFMKN_01020 2.4e-12 sidE D nuclear chromosome segregation
KIAEFMKN_01021 5.7e-36 ykuS S Belongs to the UPF0180 family
KIAEFMKN_01022 2.1e-25
KIAEFMKN_01023 0.0 6.2.1.1, 6.2.1.16 I AMP-dependent synthetase
KIAEFMKN_01024 6.7e-93 ywrA P COG2059 Chromate transport protein ChrA
KIAEFMKN_01025 1.8e-102 chrA P COG2059 Chromate transport protein ChrA
KIAEFMKN_01026 1.5e-83 ywrC K Transcriptional regulator
KIAEFMKN_01027 4.2e-231 EGP Uncharacterised MFS-type transporter YbfB
KIAEFMKN_01028 1.7e-309 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KIAEFMKN_01029 1.6e-227 3.5.1.4, 6.3.5.6, 6.3.5.7 J Belongs to the amidase family
KIAEFMKN_01030 1.3e-21 EGP Major facilitator Superfamily
KIAEFMKN_01031 2.5e-122 EGP Major facilitator Superfamily
KIAEFMKN_01033 3.8e-162 pocR K Sensory domain found in PocR
KIAEFMKN_01034 5.9e-230 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KIAEFMKN_01035 3.6e-210 yxjG 2.1.1.14 E Methionine synthase
KIAEFMKN_01036 8.7e-146 3.2.2.21 L endonuclease III
KIAEFMKN_01037 6.8e-70 L Integrase core domain
KIAEFMKN_01038 2.5e-68 L COG2801 Transposase and inactivated derivatives
KIAEFMKN_01040 3.6e-63 gloA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KIAEFMKN_01041 2.8e-59 L Transposase IS4 family protein
KIAEFMKN_01042 1.4e-37 L PFAM Transposase, IS4-like
KIAEFMKN_01043 4.9e-81 L Transposase IS4 family protein
KIAEFMKN_01044 1.9e-178 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KIAEFMKN_01045 2.2e-265 S PFAM Uncharacterised protein family UPF0236
KIAEFMKN_01046 4.1e-259 proP EGP Transporter
KIAEFMKN_01047 1.2e-62 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KIAEFMKN_01048 1.3e-97 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KIAEFMKN_01049 4.5e-174 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIAEFMKN_01051 1.2e-45
KIAEFMKN_01052 3e-139 tesE Q COG3971 2-keto-4-pentenoate hydratase
KIAEFMKN_01053 1.9e-74 nsrR K Transcriptional regulator
KIAEFMKN_01054 3.7e-216 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KIAEFMKN_01055 3e-123 S membrane transporter protein
KIAEFMKN_01056 2.8e-73 dps P Ferritin-like domain
KIAEFMKN_01057 1.5e-183 mocA S Oxidoreductase
KIAEFMKN_01058 9.8e-205 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KIAEFMKN_01059 3.9e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KIAEFMKN_01060 1.8e-81
KIAEFMKN_01061 4.7e-143 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KIAEFMKN_01062 2.8e-28 sspD S small acid-soluble spore protein
KIAEFMKN_01063 4.3e-19 S Stage 0 Sporulation Regulatory protein
KIAEFMKN_01065 1.3e-287 kinE 2.7.13.3 T Histidine kinase
KIAEFMKN_01066 2.1e-79 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KIAEFMKN_01067 3.3e-71 XK27_09985 S Protein of unknown function (DUF1232)
KIAEFMKN_01069 0.0 clpE O Belongs to the ClpA ClpB family
KIAEFMKN_01070 1.6e-180 ykvI S membrane
KIAEFMKN_01071 2.7e-106 S Abortive infection protein
KIAEFMKN_01072 2.5e-26 ykvS S protein conserved in bacteria
KIAEFMKN_01073 3.5e-27
KIAEFMKN_01074 3.2e-40 ptsH G phosphocarrier protein HPr
KIAEFMKN_01075 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KIAEFMKN_01076 3.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIAEFMKN_01077 1.2e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KIAEFMKN_01078 1.2e-213 patA 2.6.1.1 E Aminotransferase
KIAEFMKN_01079 1.6e-163 cheV 2.7.13.3 T Chemotaxis protein CheV
KIAEFMKN_01080 3.1e-86 ykyB S YkyB-like protein
KIAEFMKN_01081 0.0 ydgH S drug exporters of the RND superfamily
KIAEFMKN_01082 0.0 T Diguanylate cyclase
KIAEFMKN_01083 2e-32
KIAEFMKN_01084 9.3e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIAEFMKN_01085 3.9e-170 3.5.1.4 C Acetamidase
KIAEFMKN_01086 5.8e-39 ykuJ S protein conserved in bacteria
KIAEFMKN_01087 6.5e-78 ykuL S CBS domain
KIAEFMKN_01088 4.1e-158 ccpC K Transcriptional regulator
KIAEFMKN_01089 4.7e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KIAEFMKN_01090 1.9e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KIAEFMKN_01091 1.8e-18 S YhfH-like protein
KIAEFMKN_01092 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KIAEFMKN_01093 6.8e-30 ykzG S Belongs to the UPF0356 family
KIAEFMKN_01094 1e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KIAEFMKN_01095 1.3e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KIAEFMKN_01096 6.8e-232 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KIAEFMKN_01097 9.7e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KIAEFMKN_01098 9.2e-34
KIAEFMKN_01100 2.4e-278 speA 4.1.1.19 E Arginine
KIAEFMKN_01102 7.8e-48 yktA S Belongs to the UPF0223 family
KIAEFMKN_01103 1.4e-118 yktB S Belongs to the UPF0637 family
KIAEFMKN_01104 3.1e-24
KIAEFMKN_01105 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
KIAEFMKN_01106 7.8e-25 S Family of unknown function (DUF5325)
KIAEFMKN_01107 0.0 typA T GTP-binding protein TypA
KIAEFMKN_01108 1.2e-52 ylaH S YlaH-like protein
KIAEFMKN_01109 5.6e-250 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KIAEFMKN_01110 2.6e-88 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KIAEFMKN_01111 1.5e-43 ylaN S Belongs to the UPF0358 family
KIAEFMKN_01112 2e-217 ftsW D Belongs to the SEDS family
KIAEFMKN_01113 3.6e-174 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KIAEFMKN_01114 4.5e-166 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KIAEFMKN_01115 5.8e-205 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KIAEFMKN_01116 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KIAEFMKN_01117 1.2e-114 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KIAEFMKN_01118 1.4e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KIAEFMKN_01119 1.9e-175 ctaG S cytochrome c oxidase
KIAEFMKN_01120 3.7e-63 ylbA S YugN-like family
KIAEFMKN_01121 3.6e-180 ylbC S protein with SCP PR1 domains
KIAEFMKN_01122 4.5e-85 yiiD Q protein, possibly involved in aromatic compounds catabolism
KIAEFMKN_01123 5.8e-70 ylbD S Putative coat protein
KIAEFMKN_01124 1.4e-37 ylbE S YlbE-like protein
KIAEFMKN_01125 2.4e-65
KIAEFMKN_01127 2.5e-15
KIAEFMKN_01128 1.3e-73 ylbF S Belongs to the UPF0342 family
KIAEFMKN_01129 5.3e-46 ylbG S UPF0298 protein
KIAEFMKN_01130 2e-67 S Methylthioribose kinase
KIAEFMKN_01131 2e-106 rsmD 2.1.1.171 L Methyltransferase
KIAEFMKN_01132 1.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KIAEFMKN_01133 1.6e-219 ylbJ S Sporulation integral membrane protein YlbJ
KIAEFMKN_01134 2.4e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
KIAEFMKN_01135 1.3e-188 ylbL T Belongs to the peptidase S16 family
KIAEFMKN_01136 7.7e-244 ylbM S Belongs to the UPF0348 family
KIAEFMKN_01137 7.7e-97 yceD S metal-binding, possibly nucleic acid-binding protein
KIAEFMKN_01138 1e-26 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KIAEFMKN_01139 1.8e-84 rsfA S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KIAEFMKN_01140 8.1e-93 ylbP K n-acetyltransferase
KIAEFMKN_01141 2.4e-161 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KIAEFMKN_01142 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KIAEFMKN_01143 2e-79 mraZ K Belongs to the MraZ family
KIAEFMKN_01144 2.3e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KIAEFMKN_01145 2.5e-51 ftsL D Essential cell division protein
KIAEFMKN_01146 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KIAEFMKN_01147 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KIAEFMKN_01148 3.1e-278 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KIAEFMKN_01149 1.7e-78 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KIAEFMKN_01150 4.9e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KIAEFMKN_01151 2.5e-258 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KIAEFMKN_01152 5.9e-189 spoVE D Belongs to the SEDS family
KIAEFMKN_01153 3.5e-205 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KIAEFMKN_01154 2.4e-120 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KIAEFMKN_01155 1.1e-221 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KIAEFMKN_01156 1.2e-189 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KIAEFMKN_01157 2.3e-170 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KIAEFMKN_01158 7.7e-113 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KIAEFMKN_01159 4.9e-137 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KIAEFMKN_01160 1.9e-43 ylmC S sporulation protein
KIAEFMKN_01161 2.6e-73 yocH CBM50 M 3D domain
KIAEFMKN_01162 2.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KIAEFMKN_01163 7.8e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KIAEFMKN_01164 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KIAEFMKN_01165 2.5e-40 yggT S membrane
KIAEFMKN_01166 1.7e-145 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KIAEFMKN_01167 4.3e-65 divIVA D Cell division initiation protein
KIAEFMKN_01168 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KIAEFMKN_01170 2.2e-82 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KIAEFMKN_01171 9e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KIAEFMKN_01172 3.4e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KIAEFMKN_01173 3.6e-168 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KIAEFMKN_01174 2.7e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KIAEFMKN_01175 2.6e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KIAEFMKN_01176 0.0 carB 6.3.5.5 F Belongs to the CarB family
KIAEFMKN_01177 4.4e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KIAEFMKN_01178 2.5e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KIAEFMKN_01179 4.6e-16 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KIAEFMKN_01180 2.5e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KIAEFMKN_01181 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KIAEFMKN_01182 2.3e-156 S Nuclease-related domain
KIAEFMKN_01183 4.3e-203 L Transposase IS4 family protein
KIAEFMKN_01184 5e-167 araC1 K AraC-like ligand binding domain
KIAEFMKN_01185 4.8e-279 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KIAEFMKN_01186 9.7e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
KIAEFMKN_01187 5.2e-161 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 G Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
KIAEFMKN_01188 3.2e-32 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C hydroxyacid-oxoacid transhydrogenase activity
KIAEFMKN_01189 1.1e-74 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KIAEFMKN_01190 4.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KIAEFMKN_01191 9.6e-226 EGP Major facilitator Superfamily
KIAEFMKN_01192 8e-253 lmrB EGP the major facilitator superfamily
KIAEFMKN_01193 1.9e-98 yxaF_1 K Transcriptional regulator
KIAEFMKN_01194 2.5e-103 yyaR K Acetyltransferase (GNAT) domain
KIAEFMKN_01195 7.6e-195 S AI-2E family transporter
KIAEFMKN_01196 2e-160 S hydrolases of the HAD superfamily
KIAEFMKN_01197 0.0 S FAD binding domain
KIAEFMKN_01198 1.3e-92
KIAEFMKN_01199 5.1e-151
KIAEFMKN_01200 5.5e-86 V AAA domain, putative AbiEii toxin, Type IV TA system
KIAEFMKN_01201 6.4e-90 yihP G MFS/sugar transport protein
KIAEFMKN_01202 8.8e-248 L PFAM Transposase, IS4-like
KIAEFMKN_01203 2.1e-160 yihP G MFS/sugar transport protein
KIAEFMKN_01204 8.7e-158 pocR K Sensory domain found in PocR
KIAEFMKN_01205 6.1e-81 gldA 1.1.1.6 C Dehydrogenase
KIAEFMKN_01206 2.1e-75 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KIAEFMKN_01207 2.9e-150 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
KIAEFMKN_01208 1.3e-81 dhaL 2.7.1.121 S Dak2
KIAEFMKN_01209 1.3e-47 dhaM 2.7.1.121 S PTS system fructose IIA component
KIAEFMKN_01210 2.7e-184 dhaT 1.1.1.1, 1.1.1.202 C Iron-containing alcohol dehydrogenase
KIAEFMKN_01212 2.7e-115 sodA 1.15.1.1 P Iron/manganese superoxide dismutases, alpha-hairpin domain
KIAEFMKN_01213 2.8e-180 C 4Fe-4S single cluster domain
KIAEFMKN_01215 3.4e-42 lrpC K AsnC family transcriptional regulator
KIAEFMKN_01216 1.3e-97 purD 6.3.4.13 F phosphoribosylamine-glycine ligase activity
KIAEFMKN_01217 5.2e-53
KIAEFMKN_01219 1.5e-88 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
KIAEFMKN_01220 2e-137 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KIAEFMKN_01221 3.1e-165 yocS S -transporter
KIAEFMKN_01222 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KIAEFMKN_01223 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KIAEFMKN_01224 2.1e-152 yicC S stress-induced protein
KIAEFMKN_01225 6.5e-45 ylzA S Belongs to the UPF0296 family
KIAEFMKN_01226 1.3e-108 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KIAEFMKN_01227 3.4e-29 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KIAEFMKN_01228 4.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KIAEFMKN_01229 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KIAEFMKN_01230 8.1e-82 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KIAEFMKN_01231 5.3e-178 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KIAEFMKN_01232 4.4e-65 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KIAEFMKN_01233 9.3e-172 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KIAEFMKN_01234 7.8e-140 stp 3.1.3.16 T phosphatase
KIAEFMKN_01235 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KIAEFMKN_01236 8.8e-167 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KIAEFMKN_01237 5.9e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KIAEFMKN_01238 2.8e-125 thiN 2.7.6.2 H thiamine pyrophosphokinase
KIAEFMKN_01239 5e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KIAEFMKN_01240 1.5e-59 asp S protein conserved in bacteria
KIAEFMKN_01241 1.5e-305 yloV S kinase related to dihydroxyacetone kinase
KIAEFMKN_01242 9.6e-118 sdaAB 4.3.1.17 E L-serine dehydratase
KIAEFMKN_01243 1.3e-154 sdaAA 4.3.1.17 E L-serine dehydratase
KIAEFMKN_01244 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KIAEFMKN_01245 7.4e-98 fapR 5.3.1.23 Q Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KIAEFMKN_01246 7.8e-208 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KIAEFMKN_01247 2.8e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KIAEFMKN_01248 1.8e-128 IQ reductase
KIAEFMKN_01249 3.7e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIAEFMKN_01250 4.5e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KIAEFMKN_01251 0.0 smc D Required for chromosome condensation and partitioning
KIAEFMKN_01252 2.5e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KIAEFMKN_01253 2.6e-52 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KIAEFMKN_01254 5.1e-243 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KIAEFMKN_01255 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KIAEFMKN_01256 4.7e-35 ylqC S Belongs to the UPF0109 family
KIAEFMKN_01257 8.3e-61 ylqD S YlqD protein
KIAEFMKN_01258 1.7e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KIAEFMKN_01259 8.9e-141 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KIAEFMKN_01260 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KIAEFMKN_01261 1.6e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KIAEFMKN_01262 2.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KIAEFMKN_01263 8.7e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KIAEFMKN_01264 4.4e-233 CP_1081 D nuclear chromosome segregation
KIAEFMKN_01265 3.6e-45 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KIAEFMKN_01266 2.1e-213 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KIAEFMKN_01267 2.8e-168 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KIAEFMKN_01268 6.2e-165 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KIAEFMKN_01269 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KIAEFMKN_01272 1.9e-169 xerC L tyrosine recombinase XerC
KIAEFMKN_01273 2.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KIAEFMKN_01274 5.1e-225 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KIAEFMKN_01275 8.6e-134 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KIAEFMKN_01276 2.8e-61 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KIAEFMKN_01277 4e-75 flgC N Belongs to the flagella basal body rod proteins family
KIAEFMKN_01278 9.9e-41 fliE N Flagellar hook-basal body complex protein FliE
KIAEFMKN_01279 1.6e-248 fliF N The M ring may be actively involved in energy transduction
KIAEFMKN_01280 2.7e-164 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KIAEFMKN_01281 4e-128 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KIAEFMKN_01282 3.7e-246 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KIAEFMKN_01283 3.1e-72 fliJ N Flagellar biosynthesis chaperone
KIAEFMKN_01284 9.9e-48 ylxF S MgtE intracellular N domain
KIAEFMKN_01285 1.5e-270 fliK N Flagellar hook-length control
KIAEFMKN_01286 2.3e-108 flgD N Flagellar basal body rod modification protein
KIAEFMKN_01287 2.7e-71 flg N Putative flagellar
KIAEFMKN_01288 3.5e-132 flgG N Flagellar basal body rod
KIAEFMKN_01289 2.7e-65 fliL N Controls the rotational direction of flagella during chemotaxis
KIAEFMKN_01290 9.9e-183 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KIAEFMKN_01291 4.3e-195 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KIAEFMKN_01292 3.2e-59 cheB 3.1.1.61, 3.5.1.44 T response regulator
KIAEFMKN_01293 1.1e-116 fliZ N Flagellar biosynthesis protein, FliO
KIAEFMKN_01294 2e-107 fliP N Plays a role in the flagellum-specific transport system
KIAEFMKN_01295 1.5e-37 fliQ N Role in flagellar biosynthesis
KIAEFMKN_01296 2.5e-133 fliR N Flagellar biosynthetic protein FliR
KIAEFMKN_01297 3.4e-189 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KIAEFMKN_01298 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KIAEFMKN_01299 8.4e-207 flhF N Flagellar biosynthesis regulator FlhF
KIAEFMKN_01300 3e-156 flhG D Belongs to the ParA family
KIAEFMKN_01301 9.6e-118 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KIAEFMKN_01302 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KIAEFMKN_01303 1.1e-69 cheW NT COG0835 Chemotaxis signal transduction protein
KIAEFMKN_01304 1.5e-112 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KIAEFMKN_01305 1.6e-85 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KIAEFMKN_01306 1.8e-136 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KIAEFMKN_01307 8e-86 ylxL
KIAEFMKN_01308 6.2e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
KIAEFMKN_01309 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KIAEFMKN_01310 1.5e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KIAEFMKN_01311 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KIAEFMKN_01312 1.6e-148 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KIAEFMKN_01313 3.8e-145 cdsA 2.7.7.41 S Belongs to the CDS family
KIAEFMKN_01314 7.2e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KIAEFMKN_01315 7.4e-236 rasP M zinc metalloprotease
KIAEFMKN_01316 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KIAEFMKN_01317 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KIAEFMKN_01318 9.2e-83 rimP S Required for maturation of 30S ribosomal subunits
KIAEFMKN_01319 2.2e-221 nusA K Participates in both transcription termination and antitermination
KIAEFMKN_01320 8.2e-45 ylxR K nucleic-acid-binding protein implicated in transcription termination
KIAEFMKN_01321 2.9e-48 ylxQ J ribosomal protein
KIAEFMKN_01322 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KIAEFMKN_01323 1.1e-43 ylxP S protein conserved in bacteria
KIAEFMKN_01324 3.2e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KIAEFMKN_01325 5.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KIAEFMKN_01326 3.8e-184 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KIAEFMKN_01327 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KIAEFMKN_01328 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KIAEFMKN_01329 5.2e-209 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KIAEFMKN_01330 5.2e-234 pepR S Belongs to the peptidase M16 family
KIAEFMKN_01331 6.2e-38 ymxH S YlmC YmxH family
KIAEFMKN_01332 4.9e-190 dpaA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KIAEFMKN_01333 7.4e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KIAEFMKN_01334 3.7e-188 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KIAEFMKN_01335 2e-225 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KIAEFMKN_01336 1.5e-158 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIAEFMKN_01337 0.0 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KIAEFMKN_01338 3.8e-59 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KIAEFMKN_01339 7.4e-52 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KIAEFMKN_01340 3.3e-35 S YlzJ-like protein
KIAEFMKN_01341 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KIAEFMKN_01342 1.5e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KIAEFMKN_01343 5.6e-286 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KIAEFMKN_01344 9e-187 yufP S Belongs to the binding-protein-dependent transport system permease family
KIAEFMKN_01345 2.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
KIAEFMKN_01346 4.7e-238 ymfF S Peptidase M16
KIAEFMKN_01347 5.8e-244 ymfH S zinc protease
KIAEFMKN_01348 1e-145 1.1.1.100 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KIAEFMKN_01349 6.4e-41 ymfJ S Protein of unknown function (DUF3243)
KIAEFMKN_01350 9.9e-146 ymfK S Protein of unknown function (DUF3388)
KIAEFMKN_01351 3.7e-158 ymfM S protein conserved in bacteria
KIAEFMKN_01352 1.1e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KIAEFMKN_01353 3.6e-227 cinA 3.5.1.42 S Belongs to the CinA family
KIAEFMKN_01354 2.1e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KIAEFMKN_01355 2.5e-217 rny S Endoribonuclease that initiates mRNA decay
KIAEFMKN_01356 6.5e-153 ymdB S protein conserved in bacteria
KIAEFMKN_01357 3.3e-37 spoVS S Stage V sporulation protein S
KIAEFMKN_01358 6e-171 yegQ O Peptidase U32
KIAEFMKN_01359 3.1e-250 yegQ O COG0826 Collagenase and related proteases
KIAEFMKN_01360 3.3e-250 E Amino acid permease
KIAEFMKN_01361 0.0 KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KIAEFMKN_01362 2.8e-290 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KIAEFMKN_01363 1.4e-264 patA 2.6.1.11, 2.6.1.17, 2.6.1.82 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KIAEFMKN_01364 6.8e-300 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KIAEFMKN_01365 6.8e-48 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KIAEFMKN_01366 3.6e-99 cotE S Outer spore coat protein E (CotE)
KIAEFMKN_01367 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KIAEFMKN_01368 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KIAEFMKN_01369 5.5e-40 yhjA S Excalibur calcium-binding domain
KIAEFMKN_01370 1.6e-31 2.1.1.80, 3.1.1.61 S protein secretion by the type IV secretion system
KIAEFMKN_01373 5.8e-194 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KIAEFMKN_01374 1.2e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KIAEFMKN_01376 1.9e-175 spoVK O stage V sporulation protein K
KIAEFMKN_01377 8.7e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KIAEFMKN_01378 1.8e-245 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KIAEFMKN_01379 1.3e-170 polA 2.7.7.7 L 5'3' exonuclease
KIAEFMKN_01381 3.6e-27 ypeQ S Zinc-finger
KIAEFMKN_01382 1.2e-31 cspD K Cold-shock protein
KIAEFMKN_01383 1.2e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KIAEFMKN_01384 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KIAEFMKN_01385 4.4e-83
KIAEFMKN_01386 1.9e-118 ypgQ S phosphohydrolase
KIAEFMKN_01387 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KIAEFMKN_01388 8.3e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
KIAEFMKN_01389 5.6e-74 yphP S Belongs to the UPF0403 family
KIAEFMKN_01390 8.1e-105 ypjP S YpjP-like protein
KIAEFMKN_01391 3.1e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KIAEFMKN_01392 1.8e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KIAEFMKN_01393 1.9e-110 hlyIII S protein, Hemolysin III
KIAEFMKN_01394 4.7e-140 ypmR E COG2755 Lysophospholipase L1 and related esterases
KIAEFMKN_01395 4.6e-97 ypmS S protein conserved in bacteria
KIAEFMKN_01396 3e-267 rsmF 2.1.1.176, 2.1.1.178 J RNA-binding PUA-like domain of methyltransferase RsmF
KIAEFMKN_01397 1.1e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIAEFMKN_01398 7.3e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KIAEFMKN_01399 9e-16 S Protein of unknown function (Tiny_TM_bacill)
KIAEFMKN_01400 3e-206 NT CHASE3 domain
KIAEFMKN_01401 3e-36 yozE S Belongs to the UPF0346 family
KIAEFMKN_01402 3.9e-116 yodN
KIAEFMKN_01403 1.3e-24 yozD S YozD-like protein
KIAEFMKN_01405 6.9e-147 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KIAEFMKN_01406 5.4e-278 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KIAEFMKN_01407 2.4e-69 ypoP K transcriptional
KIAEFMKN_01408 6.5e-99 ykwD J protein with SCP PR1 domains
KIAEFMKN_01409 2.8e-249 norM V Multidrug efflux pump
KIAEFMKN_01411 2.4e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KIAEFMKN_01412 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
KIAEFMKN_01413 1.7e-132 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KIAEFMKN_01414 2.8e-106 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KIAEFMKN_01416 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KIAEFMKN_01417 2.3e-104 K Transcriptional regulator
KIAEFMKN_01418 5.4e-59 4.4.1.5 E lactoylglutathione lyase activity
KIAEFMKN_01419 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KIAEFMKN_01420 2.2e-227 ymfD EGP Major facilitator Superfamily
KIAEFMKN_01421 4.3e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIAEFMKN_01422 2.8e-255 arlS 2.7.13.3 T Histidine kinase
KIAEFMKN_01423 1.9e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
KIAEFMKN_01424 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KIAEFMKN_01425 7.3e-202 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KIAEFMKN_01426 7.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KIAEFMKN_01427 5.9e-92 rok S Repressor of ComK
KIAEFMKN_01428 6.4e-113 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KIAEFMKN_01430 1.5e-161 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KIAEFMKN_01431 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KIAEFMKN_01432 3.5e-193 yceA S Belongs to the UPF0176 family
KIAEFMKN_01433 1.6e-128 yoqW S Belongs to the SOS response-associated peptidase family
KIAEFMKN_01434 8.3e-105 thiT S Proton-coupled thiamine transporter YuaJ
KIAEFMKN_01435 1.6e-165 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KIAEFMKN_01436 2.1e-79 S Domain in cystathionine beta-synthase and other proteins.
KIAEFMKN_01437 1e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KIAEFMKN_01438 9.1e-107 yocH CBM50 M COG1388 FOG LysM repeat
KIAEFMKN_01439 0.0 topB2 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KIAEFMKN_01440 3.8e-254 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KIAEFMKN_01441 2.6e-112 E Lysine exporter protein LysE YggA
KIAEFMKN_01442 4.5e-177 corA P Mg2 transporter protein
KIAEFMKN_01443 3.3e-69 S CHY zinc finger
KIAEFMKN_01444 9e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KIAEFMKN_01445 8.1e-111 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KIAEFMKN_01446 2.4e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KIAEFMKN_01447 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KIAEFMKN_01448 1.5e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KIAEFMKN_01449 1.1e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KIAEFMKN_01450 6.6e-139 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KIAEFMKN_01451 2.3e-119 hisE 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KIAEFMKN_01452 5.9e-41 yedF O Belongs to the sulfur carrier protein TusA family
KIAEFMKN_01453 1.4e-239 yedE S Sulphur transport
KIAEFMKN_01454 3.2e-175 rarD S -transporter
KIAEFMKN_01455 9.1e-221 ktrB P COG0168 Trk-type K transport systems, membrane components
KIAEFMKN_01456 2.9e-122 P COG0569 K transport systems, NAD-binding component
KIAEFMKN_01457 3e-136 ykrK S Domain of unknown function (DUF1836)
KIAEFMKN_01458 1e-17
KIAEFMKN_01459 3.6e-48 yxcD S Protein of unknown function (DUF2653)
KIAEFMKN_01460 8.6e-218 yeaN P COG2807 Cyanate permease
KIAEFMKN_01461 0.0 ubiB S ABC1 family
KIAEFMKN_01462 4.7e-24 S ATP synthase, subunit b
KIAEFMKN_01463 2.1e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIAEFMKN_01465 2.7e-31 cspB K Cold shock
KIAEFMKN_01466 9.4e-118 folE 3.5.4.16 H GTP cyclohydrolase
KIAEFMKN_01467 6.7e-165 trxB_2 1.8.1.9 C FAD dependent oxidoreductase
KIAEFMKN_01468 5.3e-44 S Protein of unknown function (DUF1292)
KIAEFMKN_01469 8.1e-48 yxiS
KIAEFMKN_01470 0.0 bceB V ABC transporter (permease)
KIAEFMKN_01471 2.6e-135 bceA V ABC transporter, ATP-binding protein
KIAEFMKN_01472 4.7e-185 bceS 2.7.13.3 T Signal transduction histidine kinase
KIAEFMKN_01473 4.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIAEFMKN_01474 9.3e-172 S Protein of unknown function (DUF1672)
KIAEFMKN_01475 1.2e-115 S Protein of unknown function (DUF1672)
KIAEFMKN_01477 1.2e-70 ybzH K Helix-turn-helix domain
KIAEFMKN_01478 6.6e-202 ybcL EGP Major facilitator Superfamily
KIAEFMKN_01479 2.1e-196 yxaB GM Polysaccharide pyruvyl transferase
KIAEFMKN_01480 1.3e-16
KIAEFMKN_01481 6.6e-241 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KIAEFMKN_01482 3.6e-202 yetN S Protein of unknown function (DUF3900)
KIAEFMKN_01483 3.6e-151
KIAEFMKN_01485 2.9e-238 ywoD EGP Major facilitator superfamily
KIAEFMKN_01486 2.5e-52 iscA S Heme biosynthesis protein HemY
KIAEFMKN_01487 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KIAEFMKN_01488 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KIAEFMKN_01489 9.4e-43 S Small, acid-soluble spore proteins, alpha/beta type
KIAEFMKN_01490 7.6e-62 S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KIAEFMKN_01491 4.4e-110 M effector of murein hydrolase
KIAEFMKN_01492 0.0 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KIAEFMKN_01493 9.1e-115 M lytic transglycosylase activity
KIAEFMKN_01494 6.2e-09 S membrane
KIAEFMKN_01495 8.6e-19 sspP S Belongs to the SspP family
KIAEFMKN_01496 2.6e-39
KIAEFMKN_01497 6.4e-240 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KIAEFMKN_01498 2.6e-18 sspO S Belongs to the SspO family
KIAEFMKN_01499 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KIAEFMKN_01501 1e-19 sspN S Small acid-soluble spore protein N family
KIAEFMKN_01502 4.1e-31 tlp S Belongs to the Tlp family
KIAEFMKN_01503 2.2e-75 yneP S thioesterase
KIAEFMKN_01504 2.5e-52 yneQ
KIAEFMKN_01505 3.7e-53 yneR S Belongs to the HesB IscA family
KIAEFMKN_01506 9.6e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KIAEFMKN_01507 1.9e-71 yccU S CoA-binding protein
KIAEFMKN_01508 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KIAEFMKN_01509 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KIAEFMKN_01510 8.3e-145
KIAEFMKN_01511 4.1e-205 yjjL G Major facilitator superfamily
KIAEFMKN_01512 7.6e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KIAEFMKN_01513 0.0 ppdK 2.7.3.13, 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
KIAEFMKN_01514 7.9e-69 E Glyoxalase
KIAEFMKN_01519 1.3e-199 yrpB 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KIAEFMKN_01520 3.6e-102 5.1.3.34 S oxidoreductase activity
KIAEFMKN_01521 9.1e-95 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KIAEFMKN_01523 2.6e-197 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
KIAEFMKN_01524 2.7e-162 2.1.1.144, 2.1.1.197 S Methyltransferase domain
KIAEFMKN_01525 2.1e-08
KIAEFMKN_01528 4.2e-138 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KIAEFMKN_01529 2e-94 yvbK 3.1.3.25 K acetyltransferase
KIAEFMKN_01530 6.1e-93 VPA1573 J acetyltransferase
KIAEFMKN_01531 3.7e-67 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) family
KIAEFMKN_01532 7.1e-77 3.6.1.55 F Belongs to the Nudix hydrolase family
KIAEFMKN_01533 1.4e-245 cytX F Permease for cytosine/purines, uracil, thiamine, allantoin
KIAEFMKN_01534 9e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KIAEFMKN_01535 2.8e-137 IQ Enoyl-(Acyl carrier protein) reductase
KIAEFMKN_01536 5.3e-126 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KIAEFMKN_01537 4.9e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KIAEFMKN_01538 2.8e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KIAEFMKN_01539 2.5e-08 ykyB S YkyB-like protein
KIAEFMKN_01540 4.3e-126 yflK S protein conserved in bacteria
KIAEFMKN_01541 4.3e-42 S COG NOG14552 non supervised orthologous group
KIAEFMKN_01542 5.3e-43
KIAEFMKN_01544 5.3e-83 2.3.1.57 K Acetyltransferase (GNAT) domain
KIAEFMKN_01546 1.8e-215 S Psort location CytoplasmicMembrane, score
KIAEFMKN_01547 1.8e-121 yfiR K Bacterial regulatory proteins, tetR family
KIAEFMKN_01548 1.3e-196 yfiS EGP Major facilitator Superfamily
KIAEFMKN_01549 9.6e-138 thiX 2.7.1.50 P binding-protein-dependent transport systems inner membrane component
KIAEFMKN_01550 1.5e-183 nrtA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KIAEFMKN_01551 1.6e-72 S Glyoxalase bleomycin resistance protein dioxygenase
KIAEFMKN_01552 4.3e-149 yitD 4.4.1.19 S synthase
KIAEFMKN_01553 6.5e-133 comB 3.1.3.71 H Belongs to the ComB family
KIAEFMKN_01554 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KIAEFMKN_01555 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KIAEFMKN_01556 3.3e-109
KIAEFMKN_01557 2.2e-131 mta K transcriptional
KIAEFMKN_01558 1.6e-271 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
KIAEFMKN_01559 1e-102 yjlA EG Putative multidrug resistance efflux transporter
KIAEFMKN_01560 2.9e-58 yjlA EG Putative multidrug resistance efflux transporter
KIAEFMKN_01561 2e-188 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KIAEFMKN_01562 2.2e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KIAEFMKN_01563 7.4e-217 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KIAEFMKN_01564 8e-260 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KIAEFMKN_01565 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KIAEFMKN_01566 2.8e-188 kefA M Mechanosensitive ion channel
KIAEFMKN_01567 3e-192 S COG0491 Zn-dependent hydrolases, including glyoxylases
KIAEFMKN_01568 4.1e-56 I SCP-2 sterol transfer family
KIAEFMKN_01569 1.3e-170 nrdB 1.17.4.1 F Ribonucleotide reductase, small chain
KIAEFMKN_01570 1.3e-16 nrdB 1.17.4.1 F Ribonucleotide reductase, small chain
KIAEFMKN_01571 1.2e-103 S Appr-1'-p processing enzyme
KIAEFMKN_01572 2e-25 sspH S small acid-soluble spore protein
KIAEFMKN_01573 3.1e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KIAEFMKN_01574 1.1e-209 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
KIAEFMKN_01575 7.9e-293 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KIAEFMKN_01576 1.9e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KIAEFMKN_01577 3.9e-150 S Sucrose-6F-phosphate phosphohydrolase
KIAEFMKN_01578 8.7e-96 yozB S membrane
KIAEFMKN_01579 7.6e-59
KIAEFMKN_01580 3.2e-78 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KIAEFMKN_01581 5.9e-180 ldh1 1.1.1.27 C Belongs to the LDH MDH superfamily
KIAEFMKN_01582 2.9e-131 IQ Enoyl-(Acyl carrier protein) reductase
KIAEFMKN_01583 3.6e-216 fsr P COG0477 Permeases of the major facilitator superfamily
KIAEFMKN_01584 2.2e-78 sleB 3.5.1.28 M Cell wall
KIAEFMKN_01585 5.9e-148 xth 3.1.11.2 L exodeoxyribonuclease III
KIAEFMKN_01586 2.3e-156 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KIAEFMKN_01587 1.3e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KIAEFMKN_01588 1.2e-192 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
KIAEFMKN_01589 2e-211 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KIAEFMKN_01590 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KIAEFMKN_01591 1e-195 G Glycosyl hydrolases family 15
KIAEFMKN_01593 3e-22 S YpzG-like protein
KIAEFMKN_01594 2.5e-89 Q protein disulfide oxidoreductase activity
KIAEFMKN_01595 6.1e-96 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KIAEFMKN_01597 7.4e-120 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KIAEFMKN_01598 9.9e-228 mntH P H( )-stimulated, divalent metal cation uptake system
KIAEFMKN_01599 1.6e-62 dps P Ferritin-like domain
KIAEFMKN_01600 8.6e-81 V VanZ like family
KIAEFMKN_01601 1.5e-169 yhcI S ABC-2 family transporter protein
KIAEFMKN_01602 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
KIAEFMKN_01603 7.5e-58
KIAEFMKN_01604 1.4e-167 murB 1.3.1.98 M cell wall formation
KIAEFMKN_01605 2.4e-92 S Protein of unknown function (DUF1189)
KIAEFMKN_01606 2.4e-37 S Protein of unknown function (DUF1450)
KIAEFMKN_01607 7.9e-271 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KIAEFMKN_01608 1.6e-70 I MaoC like domain
KIAEFMKN_01609 2.9e-81 I N-terminal half of MaoC dehydratase
KIAEFMKN_01610 1.8e-156 IQ Enoyl-(Acyl carrier protein) reductase
KIAEFMKN_01611 5.9e-263 dld 1.1.1.303, 1.1.1.4, 1.1.2.4 C Glycolate oxidase subunit
KIAEFMKN_01613 4.2e-200 selU S tRNA 2-selenouridine synthase
KIAEFMKN_01614 3.1e-195 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
KIAEFMKN_01615 6.5e-136 T Calcineurin-like phosphoesterase superfamily domain
KIAEFMKN_01616 8.6e-193 yraQ S Predicted permease
KIAEFMKN_01617 1.7e-229 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KIAEFMKN_01618 1.2e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KIAEFMKN_01619 9.2e-72 yjlC S Protein of unknown function (DUF1641)
KIAEFMKN_01620 1.8e-220 yjlD 1.6.99.3 C NADH dehydrogenase
KIAEFMKN_01621 5.7e-230 nrnB S phosphohydrolase (DHH superfamily)
KIAEFMKN_01622 4.8e-128 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KIAEFMKN_01623 2.7e-130 yvpB NU protein conserved in bacteria
KIAEFMKN_01624 1.1e-50 tnrA K transcriptional
KIAEFMKN_01625 1.4e-109 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KIAEFMKN_01626 1.1e-23 S Virus attachment protein p12 family
KIAEFMKN_01627 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KIAEFMKN_01628 1.3e-47 feoA P COG1918 Fe2 transport system protein A
KIAEFMKN_01629 8.5e-226 dapL 2.6.1.83 E Aminotransferase
KIAEFMKN_01630 2.2e-265 argH 4.3.2.1 E argininosuccinate lyase
KIAEFMKN_01631 6.2e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KIAEFMKN_01632 1.7e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KIAEFMKN_01633 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KIAEFMKN_01634 3.9e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KIAEFMKN_01635 3e-226 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KIAEFMKN_01636 1.5e-141 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KIAEFMKN_01637 3.1e-234 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KIAEFMKN_01638 1.9e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KIAEFMKN_01640 6.5e-81
KIAEFMKN_01641 1.2e-154 yjqC P Catalase
KIAEFMKN_01642 4e-86
KIAEFMKN_01643 2.3e-30 cspD K Cold shock
KIAEFMKN_01645 4e-144 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KIAEFMKN_01646 1.5e-281 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KIAEFMKN_01647 3.9e-107 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KIAEFMKN_01648 2.1e-76 yneK S Protein of unknown function (DUF2621)
KIAEFMKN_01649 4.6e-77 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KIAEFMKN_01650 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KIAEFMKN_01651 9.9e-129 ccdA O cytochrome c biogenesis protein
KIAEFMKN_01652 6.8e-28 yneF S UPF0154 protein
KIAEFMKN_01653 4.2e-77 yneE S Sporulation inhibitor of replication protein sirA
KIAEFMKN_01654 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KIAEFMKN_01655 2.8e-32 ynzC S UPF0291 protein
KIAEFMKN_01656 1.4e-116 yneB L resolvase
KIAEFMKN_01657 4.4e-58 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KIAEFMKN_01658 3.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KIAEFMKN_01659 4.4e-263 glnA 6.3.1.2 E glutamine synthetase
KIAEFMKN_01660 4.2e-65 glnR K transcriptional
KIAEFMKN_01661 0.0 S Dynamin family
KIAEFMKN_01662 2.9e-33
KIAEFMKN_01663 1.3e-140 f42a O prohibitin homologues
KIAEFMKN_01664 4.7e-233 pbuX F xanthine
KIAEFMKN_01665 5.5e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KIAEFMKN_01666 1.7e-298 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KIAEFMKN_01667 2.7e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KIAEFMKN_01668 9e-47 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KIAEFMKN_01669 1.4e-101 ypsA S Belongs to the UPF0398 family
KIAEFMKN_01670 8.3e-46 cotD S Inner spore coat protein D
KIAEFMKN_01671 5.1e-256 yprB L RNase_H superfamily
KIAEFMKN_01672 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KIAEFMKN_01673 4.2e-77 hspX O Belongs to the small heat shock protein (HSP20) family
KIAEFMKN_01674 2.9e-71 yppG S YppG-like protein
KIAEFMKN_01675 7e-62 yppE S Bacterial domain of unknown function (DUF1798)
KIAEFMKN_01678 1.9e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KIAEFMKN_01679 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KIAEFMKN_01680 2.6e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KIAEFMKN_01681 2.3e-130 dnaD L DNA replication protein DnaD
KIAEFMKN_01682 2.2e-262 asnS 6.1.1.22 J asparaginyl-tRNA
KIAEFMKN_01683 1.7e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KIAEFMKN_01684 1.7e-78 ypmB S protein conserved in bacteria
KIAEFMKN_01685 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KIAEFMKN_01686 7.9e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KIAEFMKN_01687 2.5e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KIAEFMKN_01688 4.1e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KIAEFMKN_01689 1.4e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KIAEFMKN_01690 3.2e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KIAEFMKN_01691 8.3e-221 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KIAEFMKN_01692 3.3e-132 bshB1 S proteins, LmbE homologs
KIAEFMKN_01693 1.5e-149 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KIAEFMKN_01694 4.4e-58 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KIAEFMKN_01695 4.1e-161 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KIAEFMKN_01696 3.1e-81 queT S QueT transporter
KIAEFMKN_01697 2.4e-103 yugP S Zn-dependent protease
KIAEFMKN_01698 6e-143 ypjB S sporulation protein
KIAEFMKN_01699 4.3e-109 ypjA S membrane
KIAEFMKN_01700 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KIAEFMKN_01701 1.2e-126 petB C COG1290 Cytochrome b subunit of the bc complex
KIAEFMKN_01702 1e-98 qcrA C Menaquinol-cytochrome c reductase
KIAEFMKN_01703 2e-85 ypiF S Protein of unknown function (DUF2487)
KIAEFMKN_01704 1.7e-99 ypiB S Belongs to the UPF0302 family
KIAEFMKN_01705 4.2e-239 S COG0457 FOG TPR repeat
KIAEFMKN_01706 1.8e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KIAEFMKN_01707 1.3e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KIAEFMKN_01708 9.3e-211 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KIAEFMKN_01709 2.9e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KIAEFMKN_01710 1.8e-206 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KIAEFMKN_01711 1.2e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KIAEFMKN_01712 7.1e-144 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KIAEFMKN_01713 2.9e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KIAEFMKN_01714 1e-176 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KIAEFMKN_01715 2.8e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KIAEFMKN_01716 1e-145 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KIAEFMKN_01717 2.8e-32 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KIAEFMKN_01718 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KIAEFMKN_01719 4.1e-278 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KIAEFMKN_01720 1.2e-137 yphF
KIAEFMKN_01721 3.3e-08 yphE S Protein of unknown function (DUF2768)
KIAEFMKN_01722 7.8e-191 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KIAEFMKN_01723 4.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KIAEFMKN_01724 1.3e-17 yphA
KIAEFMKN_01725 7.3e-14 S YpzI-like protein
KIAEFMKN_01726 1e-204 rpsA 1.17.7.4 J Ribosomal protein S1
KIAEFMKN_01727 1.2e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KIAEFMKN_01728 3.5e-117 ypfA M Flagellar protein YcgR
KIAEFMKN_01729 2.9e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KIAEFMKN_01730 3.9e-150 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KIAEFMKN_01731 2e-126 prsW S Involved in the degradation of specific anti-sigma factors
KIAEFMKN_01732 3.7e-190 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KIAEFMKN_01733 1.3e-243 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KIAEFMKN_01734 1.2e-97 mecB NOT Negative regulator of genetic competence (MecA)
KIAEFMKN_01735 2.4e-144 ypbG S Calcineurin-like phosphoesterase superfamily domain
KIAEFMKN_01736 2.8e-32 cotJA S Spore coat associated protein JA (CotJA)
KIAEFMKN_01737 9.5e-45 cotJB S CotJB protein
KIAEFMKN_01738 2.3e-104 cotJC P Spore Coat
KIAEFMKN_01739 4.5e-79 ypbF S Protein of unknown function (DUF2663)
KIAEFMKN_01741 7.9e-100 ypbD S metal-dependent membrane protease
KIAEFMKN_01742 1e-284 recQ 3.6.4.12 L DNA helicase
KIAEFMKN_01743 4.9e-204 ypbB 5.1.3.1 S protein conserved in bacteria
KIAEFMKN_01744 4.7e-41 fer C Ferredoxin
KIAEFMKN_01745 1.6e-97 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KIAEFMKN_01746 5e-136 M COG0739 Membrane proteins related to metalloendopeptidases
KIAEFMKN_01747 0.0 resE 2.7.13.3 T Histidine kinase
KIAEFMKN_01748 3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIAEFMKN_01749 5.4e-228 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KIAEFMKN_01750 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KIAEFMKN_01751 1.6e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KIAEFMKN_01752 2.7e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KIAEFMKN_01753 1.4e-87 spmB S Spore maturation protein
KIAEFMKN_01754 5.2e-96 spmA S Spore maturation protein
KIAEFMKN_01755 1e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KIAEFMKN_01756 1.5e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KIAEFMKN_01757 1.9e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KIAEFMKN_01758 9e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KIAEFMKN_01759 1.4e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KIAEFMKN_01760 3.2e-270 spoVAF EG Stage V sporulation protein AF
KIAEFMKN_01761 6.6e-107 spoVAEA S Stage V sporulation protein AE
KIAEFMKN_01762 1.3e-67 spoVAB S Stage V sporulation protein AB
KIAEFMKN_01763 1.6e-111 spoVAA S Stage V sporulation protein AA
KIAEFMKN_01764 1.1e-133 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KIAEFMKN_01765 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KIAEFMKN_01766 2.5e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KIAEFMKN_01767 3.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KIAEFMKN_01768 2.7e-168 xerD L recombinase XerD
KIAEFMKN_01769 1.7e-34 S Protein of unknown function (DUF4227)
KIAEFMKN_01770 1.6e-85 fur P Belongs to the Fur family
KIAEFMKN_01771 1.1e-105 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KIAEFMKN_01772 4.2e-225 yqxK 3.6.4.12 L DNA helicase
KIAEFMKN_01773 1.6e-97 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KIAEFMKN_01775 8.4e-165 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KIAEFMKN_01778 5.2e-108 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KIAEFMKN_01779 8.2e-216 yaaN P Belongs to the TelA family
KIAEFMKN_01780 6.3e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KIAEFMKN_01781 1.6e-242 yaaH_2 M Glycoside Hydrolase Family
KIAEFMKN_01782 1e-54 S YolD-like protein
KIAEFMKN_01783 4.9e-240 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIAEFMKN_01784 2e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KIAEFMKN_01785 2.7e-138 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KIAEFMKN_01786 2.2e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KIAEFMKN_01787 4.2e-294 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KIAEFMKN_01788 6.5e-229 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIAEFMKN_01789 3.7e-79 cheW NT COG0835 Chemotaxis signal transduction protein
KIAEFMKN_01790 3.9e-204 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KIAEFMKN_01791 3e-95 yqjB S protein conserved in bacteria
KIAEFMKN_01792 6e-76 yqiW S Belongs to the UPF0403 family
KIAEFMKN_01793 8.2e-160 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KIAEFMKN_01794 2.1e-201 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KIAEFMKN_01795 8.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KIAEFMKN_01796 5.9e-188 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KIAEFMKN_01797 1.8e-259 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KIAEFMKN_01798 1.5e-208 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KIAEFMKN_01799 1e-290 bkdR 2.7.13.3 KT Transcriptional regulator
KIAEFMKN_01800 1.2e-36 yqzF S Protein of unknown function (DUF2627)
KIAEFMKN_01801 5.1e-136 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KIAEFMKN_01802 2.8e-140 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KIAEFMKN_01804 1.2e-241 rseP 3.4.21.116 M Stage IV sporulation protein B
KIAEFMKN_01805 1.9e-295 recN L May be involved in recombinational repair of damaged DNA
KIAEFMKN_01806 1.2e-79 argR K Regulates arginine biosynthesis genes
KIAEFMKN_01807 1.1e-147 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KIAEFMKN_01808 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KIAEFMKN_01809 3.3e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KIAEFMKN_01810 3.1e-31 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KIAEFMKN_01811 8.4e-238 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KIAEFMKN_01812 1.6e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KIAEFMKN_01813 1.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KIAEFMKN_01814 1.9e-68 yqhY S protein conserved in bacteria
KIAEFMKN_01815 3.7e-257 accC 6.3.4.14, 6.3.4.6, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KIAEFMKN_01816 5.2e-81 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KIAEFMKN_01817 5.5e-79 spoIIIAH S SpoIIIAH-like protein
KIAEFMKN_01818 5.6e-110 spoIIIAG S stage III sporulation protein AG
KIAEFMKN_01819 1.1e-107 spoIIIAF S stage III sporulation protein AF
KIAEFMKN_01820 3.4e-190 spoIIIAE S stage III sporulation protein AE
KIAEFMKN_01821 1.7e-58 spoIIIAD S Stage III sporulation protein AD
KIAEFMKN_01822 1.4e-27 spoIIIAC S stage III sporulation protein AC
KIAEFMKN_01823 1.7e-85 spoIIIAB S Stage III sporulation protein
KIAEFMKN_01824 1e-170 spoIIIAA S stage III sporulation protein AA
KIAEFMKN_01825 1.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KIAEFMKN_01826 1.2e-162 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KIAEFMKN_01827 5.1e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KIAEFMKN_01828 7e-86 yqhR S Conserved membrane protein YqhR
KIAEFMKN_01829 1e-165 yqhQ S Protein of unknown function (DUF1385)
KIAEFMKN_01830 1.3e-10 yqhP
KIAEFMKN_01831 8.2e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
KIAEFMKN_01832 1.4e-167 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KIAEFMKN_01833 4e-175 paaX K PaaX-like protein
KIAEFMKN_01834 2.9e-221 paaJ 2.3.1.16, 2.3.1.174, 2.3.1.223, 2.3.1.9 I Belongs to the thiolase family
KIAEFMKN_01835 6.3e-154 ditN 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
KIAEFMKN_01836 3.7e-290 aldA 1.2.1.3, 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KIAEFMKN_01837 2e-25 paaG 5.3.3.18 I Enoyl-CoA hydratase
KIAEFMKN_01838 2.1e-79 ycgT 1.18.1.2, 1.19.1.1 C reductase
KIAEFMKN_01840 0.0 nrdA 1.17.4.1 F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
KIAEFMKN_01841 1.2e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KIAEFMKN_01842 1.7e-66 yqhL P COG0607 Rhodanese-related sulfurtransferase
KIAEFMKN_01843 4.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KIAEFMKN_01844 2.9e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KIAEFMKN_01845 5.8e-216 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KIAEFMKN_01846 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KIAEFMKN_01847 5.3e-155 yqhG S Bacterial protein YqhG of unknown function
KIAEFMKN_01848 6.7e-10 yqzE S YqzE-like protein
KIAEFMKN_01849 2.6e-100 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KIAEFMKN_01850 6e-61 S ComG operon protein 7
KIAEFMKN_01851 1.1e-83 comGF U COG4940 Competence protein ComGF
KIAEFMKN_01853 7.2e-77 gspH NU COG2165 Type II secretory pathway, pseudopilin PulG
KIAEFMKN_01854 4e-50 comGC U Required for transformation and DNA binding
KIAEFMKN_01855 1.7e-176 comGB NU COG1459 Type II secretory pathway, component PulF
KIAEFMKN_01856 7.4e-211 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KIAEFMKN_01857 3.1e-130 K Helix-turn-helix domain
KIAEFMKN_01858 5.7e-36 yqgY S Protein of unknown function (DUF2626)
KIAEFMKN_01859 1e-124 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KIAEFMKN_01860 7.5e-22 yqgW S Protein of unknown function (DUF2759)
KIAEFMKN_01861 8.4e-179 glcK 2.7.1.2 G Glucokinase
KIAEFMKN_01862 3.3e-30 yqgQ S protein conserved in bacteria
KIAEFMKN_01863 1.4e-206 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KIAEFMKN_01865 1.6e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KIAEFMKN_01866 1.2e-53 yqzD
KIAEFMKN_01867 0.0 mrdA 3.4.16.4 M penicillin-binding protein
KIAEFMKN_01868 2e-217 yqgE EGP Major facilitator superfamily
KIAEFMKN_01869 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KIAEFMKN_01870 9.9e-55 fimV NU Tfp pilus assembly protein FimV
KIAEFMKN_01871 7.3e-203 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KIAEFMKN_01872 4.9e-113 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KIAEFMKN_01873 3.8e-75 zur P Belongs to the Fur family
KIAEFMKN_01874 1.8e-140 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KIAEFMKN_01875 6.4e-142 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KIAEFMKN_01876 1.3e-19 yqfT S Protein of unknown function (DUF2624)
KIAEFMKN_01877 4.9e-124 usp CBM50 M protein conserved in bacteria
KIAEFMKN_01878 6.6e-170 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KIAEFMKN_01879 2.7e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KIAEFMKN_01882 1.7e-179 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KIAEFMKN_01883 2.5e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KIAEFMKN_01884 4.3e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
KIAEFMKN_01885 2e-63 cccA C Cytochrome C oxidase, cbb3-type, subunit III
KIAEFMKN_01886 2.1e-86
KIAEFMKN_01887 2e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KIAEFMKN_01888 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KIAEFMKN_01889 1.8e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KIAEFMKN_01890 4.5e-112 ccpN K CBS domain
KIAEFMKN_01891 3.1e-144 recO L Involved in DNA repair and RecF pathway recombination
KIAEFMKN_01892 3e-08 S YqzL-like protein
KIAEFMKN_01893 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KIAEFMKN_01894 3e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KIAEFMKN_01895 9.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KIAEFMKN_01896 0.0 yqfF S membrane-associated HD superfamily hydrolase
KIAEFMKN_01897 2.3e-173 phoH T Phosphate starvation-inducible protein PhoH
KIAEFMKN_01898 1.2e-224 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KIAEFMKN_01899 4.2e-46 yqfC S sporulation protein YqfC
KIAEFMKN_01900 5.4e-72 yqeY S Yqey-like protein
KIAEFMKN_01901 9.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KIAEFMKN_01902 2.4e-267 S PFAM Uncharacterised protein family UPF0236
KIAEFMKN_01903 2.2e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KIAEFMKN_01904 3.3e-156 yqeW P COG1283 Na phosphate symporter
KIAEFMKN_01905 5.5e-261 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KIAEFMKN_01906 1.6e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KIAEFMKN_01907 1.7e-173 prmA J Methylates ribosomal protein L11
KIAEFMKN_01908 1.5e-206 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KIAEFMKN_01909 2.5e-309 dnaK O Heat shock 70 kDa protein
KIAEFMKN_01910 1.9e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KIAEFMKN_01911 3.2e-189 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KIAEFMKN_01912 1.3e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
KIAEFMKN_01913 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KIAEFMKN_01914 3.6e-224 spoIIP M stage II sporulation protein P
KIAEFMKN_01915 9.1e-198 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KIAEFMKN_01916 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
KIAEFMKN_01917 1.4e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
KIAEFMKN_01918 3.1e-07 S YqzM-like protein
KIAEFMKN_01919 0.0 comEC S Competence protein ComEC
KIAEFMKN_01920 4.2e-112 comEB 3.5.4.12 F COG2131 Deoxycytidylate deaminase
KIAEFMKN_01921 4e-85 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KIAEFMKN_01922 1.4e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KIAEFMKN_01923 6.1e-145 cmoA S Methyltransferase domain
KIAEFMKN_01924 6.4e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KIAEFMKN_01925 9.2e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KIAEFMKN_01926 3.8e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KIAEFMKN_01927 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KIAEFMKN_01928 1.2e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KIAEFMKN_01929 3.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KIAEFMKN_01930 2.6e-94 yqeG S hydrolase of the HAD superfamily
KIAEFMKN_01931 1e-259 glcF C Glycolate oxidase
KIAEFMKN_01932 2.3e-254 glcD 1.1.3.15 C Glycolate oxidase subunit
KIAEFMKN_01933 1.1e-193 ysfB KT regulator
KIAEFMKN_01934 1e-225 mco 1.16.3.3 Q multicopper oxidases
KIAEFMKN_01935 4e-72 hsp18 O Belongs to the small heat shock protein (HSP20) family
KIAEFMKN_01936 4.9e-16 S Short C-terminal domain
KIAEFMKN_01937 1.9e-88 CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KIAEFMKN_01939 4.2e-104 S TPM domain
KIAEFMKN_01940 2.1e-76 lemA S LemA family
KIAEFMKN_01941 2.5e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KIAEFMKN_01942 4e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KIAEFMKN_01943 1.6e-118 S VIT family
KIAEFMKN_01944 6.1e-155 czcD P COG1230 Co Zn Cd efflux system component
KIAEFMKN_01945 1.6e-14 sda S Sporulation inhibitor A
KIAEFMKN_01946 2.4e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KIAEFMKN_01947 2.1e-126 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KIAEFMKN_01949 4.3e-294 ahpF O Alkyl hydroperoxide reductase
KIAEFMKN_01950 1.4e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KIAEFMKN_01952 1.7e-10 S YrhC-like protein
KIAEFMKN_01953 2.1e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KIAEFMKN_01954 1.2e-29 yrzA S Protein of unknown function (DUF2536)
KIAEFMKN_01955 5.5e-59 yrrS S Protein of unknown function (DUF1510)
KIAEFMKN_01956 5.8e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KIAEFMKN_01957 6.8e-113 udk 2.7.1.48 F Cytidine monophosphokinase
KIAEFMKN_01958 3.1e-113 yrrM 2.1.1.104 S O-methyltransferase
KIAEFMKN_01959 3.8e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KIAEFMKN_01960 1.5e-41 yrzB S Belongs to the UPF0473 family
KIAEFMKN_01961 8.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KIAEFMKN_01962 5.8e-45 yrzL S Belongs to the UPF0297 family
KIAEFMKN_01963 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KIAEFMKN_01964 2.4e-174 yrrI S AI-2E family transporter
KIAEFMKN_01966 1.8e-29 yrzR
KIAEFMKN_01967 1.8e-67 yndM S Protein of unknown function (DUF2512)
KIAEFMKN_01968 7.8e-58 K helix_turn_helix ASNC type
KIAEFMKN_01969 1.6e-60 pdh 1.4.1.20, 1.4.1.9 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
KIAEFMKN_01971 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KIAEFMKN_01972 7.4e-126 S COG0457 FOG TPR repeat
KIAEFMKN_01973 3.4e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KIAEFMKN_01974 1.5e-211 iscS 2.8.1.7 E Cysteine desulfurase
KIAEFMKN_01975 2.3e-72 cymR K Transcriptional regulator
KIAEFMKN_01976 1.5e-26
KIAEFMKN_01977 6.7e-136 IQ Short-chain dehydrogenase reductase sdr
KIAEFMKN_01978 3e-237 cshA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KIAEFMKN_01979 3.1e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KIAEFMKN_01980 5.5e-162 ybaS 1.1.1.58 S Na -dependent transporter
KIAEFMKN_01982 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KIAEFMKN_01983 5.4e-250 hisS 6.1.1.21 J histidyl-tRNA synthetase
KIAEFMKN_01985 6.3e-271 lytH 3.5.1.28, 6.1.1.12 M COG3103 SH3 domain protein
KIAEFMKN_01986 0.0 yhcA5 EGP Major facilitator Superfamily
KIAEFMKN_01987 1.2e-107 emrA V Barrel-sandwich domain of CusB or HlyD membrane-fusion
KIAEFMKN_01988 5.3e-72 K helix_turn_helix multiple antibiotic resistance protein
KIAEFMKN_01989 7.1e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KIAEFMKN_01990 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KIAEFMKN_01991 9e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KIAEFMKN_01992 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KIAEFMKN_01993 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KIAEFMKN_01994 1.2e-54 yrzD S Post-transcriptional regulator
KIAEFMKN_01995 2.9e-274 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KIAEFMKN_01996 9.5e-110 yrbG S membrane
KIAEFMKN_01997 1.4e-63 yrzE S Protein of unknown function (DUF3792)
KIAEFMKN_01998 8.7e-51 yajC U Preprotein translocase subunit YajC
KIAEFMKN_01999 1.2e-224 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KIAEFMKN_02000 9.8e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KIAEFMKN_02001 3.2e-27 yrzS S Protein of unknown function (DUF2905)
KIAEFMKN_02002 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KIAEFMKN_02003 1.3e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KIAEFMKN_02004 3.8e-128 yebC K transcriptional regulatory protein
KIAEFMKN_02005 8.9e-189 1.1.1.34, 2.7.1.89 M choline kinase involved in LPS biosynthesis
KIAEFMKN_02006 8.8e-136 safA M spore coat assembly protein SafA
KIAEFMKN_02007 4e-96 niaR S small molecule binding protein (contains 3H domain)
KIAEFMKN_02008 1.1e-158 pheA 4.2.1.51 E Prephenate dehydratase
KIAEFMKN_02009 1.2e-74 pheB 5.4.99.5 S Belongs to the UPF0735 family
KIAEFMKN_02010 9.9e-244 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KIAEFMKN_02011 2e-97 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KIAEFMKN_02012 1.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KIAEFMKN_02013 3.5e-52 ysxB J ribosomal protein
KIAEFMKN_02014 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
KIAEFMKN_02015 2.9e-279 rng J ribonuclease, Rne Rng family
KIAEFMKN_02016 8.3e-162 spoIVFB S Stage IV sporulation protein
KIAEFMKN_02017 1.5e-135 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KIAEFMKN_02018 1e-145 minD D Belongs to the ParA family
KIAEFMKN_02019 2.6e-121 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KIAEFMKN_02020 2.4e-87 mreD M shape-determining protein
KIAEFMKN_02021 4.4e-139 mreC M Involved in formation and maintenance of cell shape
KIAEFMKN_02022 6.9e-184 mreB D Rod shape-determining protein MreB
KIAEFMKN_02023 1.1e-121 radC E Belongs to the UPF0758 family
KIAEFMKN_02024 1.3e-171 spoIIB
KIAEFMKN_02025 4.2e-133 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KIAEFMKN_02026 1.2e-102
KIAEFMKN_02029 2.2e-251 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KIAEFMKN_02030 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KIAEFMKN_02031 9.5e-26
KIAEFMKN_02032 1.6e-227 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KIAEFMKN_02033 1.7e-184 spoVID M stage VI sporulation protein D
KIAEFMKN_02034 7.8e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KIAEFMKN_02035 9.3e-186 hemB 4.2.1.24 H Belongs to the ALAD family
KIAEFMKN_02036 2.9e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KIAEFMKN_02037 1.1e-167 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KIAEFMKN_02038 7.7e-149 hemX O cytochrome C
KIAEFMKN_02039 1.2e-241 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KIAEFMKN_02040 4.5e-88 ysxD
KIAEFMKN_02041 4.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KIAEFMKN_02042 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KIAEFMKN_02043 2.2e-309 lonB 3.4.21.53 LO Belongs to the peptidase S16 family
KIAEFMKN_02044 1.7e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KIAEFMKN_02045 2.1e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KIAEFMKN_02046 5.7e-183 trxA2 O COG0457 FOG TPR repeat
KIAEFMKN_02047 5.3e-72 S Protein of unknown function (DUF2512)
KIAEFMKN_02048 6.3e-45
KIAEFMKN_02049 2.2e-08
KIAEFMKN_02051 1.4e-92 ysnB S Phosphoesterase
KIAEFMKN_02052 1.6e-106 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KIAEFMKN_02053 7.8e-191 gerM S COG5401 Spore germination protein
KIAEFMKN_02054 4.3e-13
KIAEFMKN_02055 2.6e-46 M Spore coat protein
KIAEFMKN_02056 6.1e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KIAEFMKN_02057 1.6e-61 yraF M Spore coat protein
KIAEFMKN_02058 1.3e-31 yraG S Spore Coat Protein
KIAEFMKN_02059 5.8e-149 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KIAEFMKN_02060 2.7e-79 ysmB 2.4.2.28 K transcriptional
KIAEFMKN_02061 6.5e-93 S GDYXXLXY protein
KIAEFMKN_02062 5.5e-195 S Predicted membrane protein (DUF2157)
KIAEFMKN_02064 2.3e-31 gerE K Transcriptional regulator
KIAEFMKN_02065 2.2e-87 ysmA S thioesterase
KIAEFMKN_02066 3.5e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KIAEFMKN_02067 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KIAEFMKN_02068 1.7e-105 sdhC C succinate dehydrogenase
KIAEFMKN_02069 1.7e-81 yslB S Protein of unknown function (DUF2507)
KIAEFMKN_02070 1.6e-219 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KIAEFMKN_02071 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KIAEFMKN_02072 6.7e-53 trxA O Belongs to the thioredoxin family
KIAEFMKN_02073 1.1e-173 etfA C Electron transfer flavoprotein
KIAEFMKN_02074 1.6e-127 etfB C Electron transfer flavoprotein
KIAEFMKN_02075 1.7e-137 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KIAEFMKN_02076 1.6e-103 fadR K Transcriptional regulator
KIAEFMKN_02077 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KIAEFMKN_02078 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KIAEFMKN_02079 0.0 polX L COG1796 DNA polymerase IV (family X)
KIAEFMKN_02080 4.9e-88 cvpA S membrane protein, required for colicin V production
KIAEFMKN_02081 7.3e-46 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KIAEFMKN_02082 9.2e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KIAEFMKN_02083 2.9e-46 KT Transcriptional
KIAEFMKN_02084 1e-86 V Mate efflux family protein
KIAEFMKN_02085 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KIAEFMKN_02086 1.1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KIAEFMKN_02087 3.3e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KIAEFMKN_02088 2.2e-31 sspI S Belongs to the SspI family
KIAEFMKN_02089 2.4e-77
KIAEFMKN_02090 1.4e-22 S Domain of unknown function (DUF5085)
KIAEFMKN_02091 5.2e-122 M1-1017 S Protein of unknown function (DUF1129)
KIAEFMKN_02092 1.5e-55 K Transcriptional regulator
KIAEFMKN_02093 2.3e-11 S NADPH-dependent FMN reductase
KIAEFMKN_02094 6.7e-127 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KIAEFMKN_02095 6.8e-178 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KIAEFMKN_02096 4.7e-102 yieF S NAD(P)H-dependent FMN reductase
KIAEFMKN_02097 3.4e-122 mcpB3 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KIAEFMKN_02098 1.2e-180 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KIAEFMKN_02099 2.5e-94 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KIAEFMKN_02100 3.5e-266 M O-Antigen ligase
KIAEFMKN_02101 7.3e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KIAEFMKN_02103 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KIAEFMKN_02104 3.4e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KIAEFMKN_02105 4.5e-112 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KIAEFMKN_02106 2.3e-224 G Transmembrane secretion effector
KIAEFMKN_02107 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KIAEFMKN_02108 1.2e-152 ytxC S YtxC-like family
KIAEFMKN_02109 9e-178 dnaI L Primosomal protein DnaI
KIAEFMKN_02110 2.8e-260 dnaB L Membrane attachment protein
KIAEFMKN_02111 2.1e-79 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KIAEFMKN_02112 5.8e-129 2.3.1.178 J Benzoate transporter
KIAEFMKN_02113 3.8e-229 L PFAM Transposase, IS116 IS110 IS902
KIAEFMKN_02114 1.2e-205 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KIAEFMKN_02115 1.3e-232 KT transcriptional regulatory protein
KIAEFMKN_02116 2e-191 E Belongs to the ABC transporter superfamily
KIAEFMKN_02117 3.8e-190 oppD P Belongs to the ABC transporter superfamily
KIAEFMKN_02118 1.2e-158 EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIAEFMKN_02119 4.3e-181 EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIAEFMKN_02120 3.7e-279 E Bacterial extracellular solute-binding proteins, family 5 Middle
KIAEFMKN_02121 1.4e-217 amhX S amidohydrolase
KIAEFMKN_02122 5.3e-294 S MlrC C-terminus
KIAEFMKN_02124 4.9e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KIAEFMKN_02125 7.9e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KIAEFMKN_02126 1.6e-109 ytaF P Probably functions as a manganese efflux pump
KIAEFMKN_02127 4e-153 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KIAEFMKN_02128 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KIAEFMKN_02129 6.8e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KIAEFMKN_02130 4e-245 icd 1.1.1.42 C isocitrate
KIAEFMKN_02131 1.5e-208 citZ 2.3.3.1 C Belongs to the citrate synthase family
KIAEFMKN_02132 1e-73 yeaL S Membrane
KIAEFMKN_02133 1.3e-159 ytvI S sporulation integral membrane protein YtvI
KIAEFMKN_02134 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KIAEFMKN_02135 2.4e-178 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KIAEFMKN_02136 1.1e-178 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KIAEFMKN_02137 4e-164 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KIAEFMKN_02138 1.5e-228 ytsJ 1.1.1.38 C Malate dehydrogenase
KIAEFMKN_02139 0.0 dnaE 2.7.7.7 L DNA polymerase
KIAEFMKN_02140 1.6e-41 ytrH S Sporulation protein YtrH
KIAEFMKN_02141 4.2e-89 ytrI
KIAEFMKN_02142 1.4e-178 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KIAEFMKN_02143 1.9e-44 ytpI S YtpI-like protein
KIAEFMKN_02144 8e-241 ytoI K transcriptional regulator containing CBS domains
KIAEFMKN_02145 1.5e-129 ytkL S Belongs to the UPF0173 family
KIAEFMKN_02146 1.5e-205 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KIAEFMKN_02147 5.2e-201 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KIAEFMKN_02148 5.6e-80 uspA T Belongs to the universal stress protein A family
KIAEFMKN_02149 5e-156 S EcsC protein family
KIAEFMKN_02150 2.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KIAEFMKN_02151 7.3e-178 ytxK 2.1.1.72 L DNA methylase
KIAEFMKN_02152 9.9e-91 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KIAEFMKN_02153 1.7e-68 ytfJ S Sporulation protein YtfJ
KIAEFMKN_02154 8e-120 ytfI S Protein of unknown function (DUF2953)
KIAEFMKN_02155 4.8e-88 yteJ S RDD family
KIAEFMKN_02156 5.1e-187 sppA OU signal peptide peptidase SppA
KIAEFMKN_02157 3.7e-309 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KIAEFMKN_02158 1.4e-27 sspB S spore protein
KIAEFMKN_02159 1.9e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KIAEFMKN_02160 2.5e-214 iscS2 2.8.1.7 E Cysteine desulfurase
KIAEFMKN_02161 3.4e-308 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KIAEFMKN_02162 4.6e-117 yttP K Transcriptional regulator
KIAEFMKN_02163 5.4e-86 ytsP 1.8.4.14 T GAF domain-containing protein
KIAEFMKN_02164 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KIAEFMKN_02165 1.9e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KIAEFMKN_02166 6.8e-184 putA E Proline dehydrogenase
KIAEFMKN_02167 9.9e-299 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KIAEFMKN_02168 1.6e-255 prdR KT Transcriptional regulator
KIAEFMKN_02169 2.2e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KIAEFMKN_02170 3.3e-152 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KIAEFMKN_02171 1.5e-211 L Transposase
KIAEFMKN_02172 3.2e-15 S Ribbon-helix-helix protein, copG family
KIAEFMKN_02173 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KIAEFMKN_02174 4.4e-89 yrhD S Protein of unknown function (DUF1641)
KIAEFMKN_02175 2.1e-193 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KIAEFMKN_02176 2.7e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KIAEFMKN_02177 3e-34 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KIAEFMKN_02178 3.9e-78 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KIAEFMKN_02179 3.4e-88 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KIAEFMKN_02180 1.5e-236 moeA 2.10.1.1 H molybdopterin
KIAEFMKN_02181 6.6e-122 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KIAEFMKN_02182 1.4e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KIAEFMKN_02183 8.4e-204 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KIAEFMKN_02184 1.5e-129 modC 3.6.3.29 P ATPases associated with a variety of cellular activities
KIAEFMKN_02185 7.7e-121 P COG4149 ABC-type molybdate transport system, permease component
KIAEFMKN_02186 6.1e-132 modA P Molybdenum ABC transporter
KIAEFMKN_02187 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KIAEFMKN_02188 5.2e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KIAEFMKN_02189 1.1e-118 acuB S Acetoin utilization protein AcuB
KIAEFMKN_02190 5.4e-233 acuC BQ histone deacetylase
KIAEFMKN_02191 1.3e-182 ccpA K catabolite control protein A
KIAEFMKN_02192 3.8e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KIAEFMKN_02193 4.2e-33 XK27_07760 S COG4980 Gas vesicle protein
KIAEFMKN_02194 5.6e-52 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KIAEFMKN_02195 8.8e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KIAEFMKN_02196 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KIAEFMKN_02197 6.1e-69 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KIAEFMKN_02198 4.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KIAEFMKN_02199 3.4e-146 ytpQ S Belongs to the UPF0354 family
KIAEFMKN_02200 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KIAEFMKN_02201 6.5e-207 rsbU 3.1.3.3 T response regulator
KIAEFMKN_02202 7.3e-155 cheR 2.1.1.80 NT chemotaxis
KIAEFMKN_02203 5.8e-72 T PhoQ Sensor
KIAEFMKN_02204 0.0 T PhoQ Sensor
KIAEFMKN_02205 2.2e-192 EGP Transmembrane secretion effector
KIAEFMKN_02207 3.8e-33
KIAEFMKN_02208 6.1e-91 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KIAEFMKN_02209 6.8e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KIAEFMKN_02210 3.3e-52 ytzB S small secreted protein
KIAEFMKN_02211 8.2e-170 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KIAEFMKN_02213 7.6e-134 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KIAEFMKN_02214 8.8e-59 ytzH S YtzH-like protein
KIAEFMKN_02215 6.4e-130 ytmP 2.7.1.89 M Phosphotransferase
KIAEFMKN_02216 4e-149 ytlQ
KIAEFMKN_02217 2e-108 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KIAEFMKN_02219 2.3e-159 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KIAEFMKN_02220 1.8e-275 pepV 3.5.1.18 E Dipeptidase
KIAEFMKN_02221 1.2e-32 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KIAEFMKN_02222 7e-287 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KIAEFMKN_02223 4.1e-26 yteV S Sporulation protein Cse60
KIAEFMKN_02224 1.7e-10
KIAEFMKN_02226 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KIAEFMKN_02227 4.3e-185 yttB EGP Major facilitator Superfamily
KIAEFMKN_02228 1.6e-42 ytzC S Protein of unknown function (DUF2524)
KIAEFMKN_02229 5.2e-104 ytqB J Putative rRNA methylase
KIAEFMKN_02231 1e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KIAEFMKN_02232 1.7e-119 ytpA 3.1.1.5 I Alpha beta hydrolase
KIAEFMKN_02233 2.1e-72 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KIAEFMKN_02234 0.0 asnB 6.3.5.4 E Asparagine synthase
KIAEFMKN_02235 5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KIAEFMKN_02236 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KIAEFMKN_02237 4.8e-69 3.6.1.13, 3.6.1.55 L NTP pyrophosphohydrolases including oxidative damage repair enzymes
KIAEFMKN_02238 1.1e-208 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KIAEFMKN_02239 1.3e-101 ywqN S NAD(P)H-dependent
KIAEFMKN_02240 1.9e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KIAEFMKN_02241 2.8e-185 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KIAEFMKN_02242 6.1e-140 ytlC P ABC transporter
KIAEFMKN_02243 1.6e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KIAEFMKN_02244 4.8e-84 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KIAEFMKN_02245 7.4e-39
KIAEFMKN_02246 5.6e-77 dps P Belongs to the Dps family
KIAEFMKN_02247 1.3e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KIAEFMKN_02249 6.3e-165 adcA P Belongs to the bacterial solute-binding protein 9 family
KIAEFMKN_02250 1.6e-23 S Domain of Unknown Function (DUF1540)
KIAEFMKN_02251 1.5e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KIAEFMKN_02252 1.9e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KIAEFMKN_02253 7.1e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KIAEFMKN_02254 4.8e-148 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KIAEFMKN_02255 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KIAEFMKN_02256 2.9e-254 menF 5.4.4.2 HQ Isochorismate synthase
KIAEFMKN_02257 3.8e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KIAEFMKN_02267 3e-09
KIAEFMKN_02273 5.1e-08
KIAEFMKN_02274 1.6e-08
KIAEFMKN_02278 1.7e-41
KIAEFMKN_02279 4.3e-42 S COG NOG14552 non supervised orthologous group
KIAEFMKN_02280 6e-232 wbbX GT2,GT4 M transferase activity, transferring glycosyl groups
KIAEFMKN_02282 1.2e-56 V ATPases associated with a variety of cellular activities
KIAEFMKN_02283 3e-69 S Protein of unknown function (DUF1430)
KIAEFMKN_02284 4.4e-17
KIAEFMKN_02285 1.8e-151 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KIAEFMKN_02286 9.1e-103 sapB S MgtC SapB transporter
KIAEFMKN_02287 7.6e-165 S Protein of unknown function (DUF1646)
KIAEFMKN_02288 8.7e-31 EGP Major facilitator Superfamily
KIAEFMKN_02289 0.0 copA 3.6.3.54 P P-type ATPase
KIAEFMKN_02290 1.8e-30 P Copper resistance protein CopZ
KIAEFMKN_02291 7.8e-55 S protein conserved in bacteria
KIAEFMKN_02292 2.3e-69 lrpC K Transcriptional regulator
KIAEFMKN_02293 5.3e-74 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KIAEFMKN_02294 6.8e-223 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KIAEFMKN_02295 5.1e-27 yhjC S Protein of unknown function (DUF3311)
KIAEFMKN_02296 4.7e-266 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KIAEFMKN_02298 4.1e-13 yhjQ C COG1145 Ferredoxin
KIAEFMKN_02300 7.7e-11 recN L Putative cell-wall binding lipoprotein
KIAEFMKN_02301 4.1e-175 nodB1 G deacetylase
KIAEFMKN_02305 1.7e-178 tnp4 L Transposase, Mutator family
KIAEFMKN_02306 1.6e-244 P Voltage gated chloride channel
KIAEFMKN_02307 1.9e-49 P Rhodanese domain protein
KIAEFMKN_02308 8.6e-38 yhjE S protein conserved in bacteria
KIAEFMKN_02309 2.4e-136 yokF 3.1.31.1 L RNA catabolic process
KIAEFMKN_02310 7.3e-71 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
KIAEFMKN_02311 4e-303 araB 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
KIAEFMKN_02312 2.2e-281 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KIAEFMKN_02313 3.5e-181 gguB G Belongs to the binding-protein-dependent transport system permease family
KIAEFMKN_02314 2.3e-284 araG 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KIAEFMKN_02315 1.3e-196 chvE G ABC transporter
KIAEFMKN_02316 1.7e-210 araR K transcriptional
KIAEFMKN_02317 3.8e-281 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KIAEFMKN_02318 2.7e-131 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KIAEFMKN_02319 1.8e-254 araP EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KIAEFMKN_02320 1.7e-306 araB 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
KIAEFMKN_02321 8.6e-215 araR K transcriptional
KIAEFMKN_02322 5.8e-214 NT chemotaxis protein
KIAEFMKN_02323 5.3e-127 plsB 2.3.1.15 I Acyl-transferase
KIAEFMKN_02324 2.3e-201 2.4.1.83 GT2 M Glycosyl transferase family 2
KIAEFMKN_02325 2.1e-140 IQ Enoyl-(Acyl carrier protein) reductase
KIAEFMKN_02326 6e-74 yuiD S protein conserved in bacteria
KIAEFMKN_02327 1.5e-214 solA 1.5.3.1 E FAD dependent oxidoreductase
KIAEFMKN_02328 5.8e-219 FOXRED 1.5.3.1 E FAD dependent oxidoreductase
KIAEFMKN_02329 1.6e-277 ycbD 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KIAEFMKN_02330 1.1e-167 4.3.1.12 E ornithine cyclodeaminase
KIAEFMKN_02333 3.7e-182 yugO P COG1226 Kef-type K transport systems
KIAEFMKN_02334 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
KIAEFMKN_02335 6.7e-34 yuzA S Domain of unknown function (DUF378)
KIAEFMKN_02336 1.5e-85 K Bacterial transcription activator, effector binding domain
KIAEFMKN_02339 1.2e-64 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KIAEFMKN_02340 5.9e-29 K Helix-turn-helix XRE-family like proteins
KIAEFMKN_02341 6.1e-196 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KIAEFMKN_02342 1.6e-165 S reductase
KIAEFMKN_02343 4.9e-159 dkgB S Aldo/keto reductase family
KIAEFMKN_02344 2.4e-239 S protein conserved in bacteria
KIAEFMKN_02346 2.1e-111 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KIAEFMKN_02347 9.9e-67 kapB G Kinase associated protein B
KIAEFMKN_02348 3.4e-143
KIAEFMKN_02349 1e-209 hcnC 1.4.99.5 E FAD dependent oxidoreductase
KIAEFMKN_02350 1.1e-52 thcD 1.14.13.111, 1.18.1.3, 1.7.1.15 S BFD-like [2Fe-2S] binding domain
KIAEFMKN_02351 1.1e-206 C HI0933-like protein
KIAEFMKN_02352 4.6e-57 1.2.5.3, 1.3.99.16 C 2 iron, 2 sulfur cluster binding
KIAEFMKN_02353 2.5e-13 S double-stranded DNA endodeoxyribonuclease activity
KIAEFMKN_02354 8.3e-160 S transposase or invertase
KIAEFMKN_02355 1.5e-190 yuxJ EGP Major facilitator Superfamily
KIAEFMKN_02356 9.4e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
KIAEFMKN_02357 5.3e-62 yuzC
KIAEFMKN_02359 1.8e-188 E Spore germination protein
KIAEFMKN_02360 1.9e-220 gerKC S spore germination
KIAEFMKN_02361 5.1e-293 gerKA EG Spore germination protein
KIAEFMKN_02363 7.5e-307 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KIAEFMKN_02364 4.1e-107 yuiC S protein conserved in bacteria
KIAEFMKN_02365 9.5e-47 yuiB S Putative membrane protein
KIAEFMKN_02366 4e-231 yumB 1.6.99.3 C NADH dehydrogenase
KIAEFMKN_02367 6.1e-185 yumC 1.18.1.2, 1.19.1.1 C reductase
KIAEFMKN_02368 3.1e-56 S response to antibiotic
KIAEFMKN_02369 5.3e-78 tcaA S response to antibiotic
KIAEFMKN_02370 2.3e-73 ycdA S Domain of unknown function (DUF4352)
KIAEFMKN_02372 2.2e-63 erpA S Belongs to the HesB IscA family
KIAEFMKN_02373 5.6e-61 yuzD S protein conserved in bacteria
KIAEFMKN_02374 5.1e-37 nifU O COG0694 Thioredoxin-like proteins and domains
KIAEFMKN_02375 3.1e-200 yutH S Spore coat protein
KIAEFMKN_02376 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KIAEFMKN_02377 5.6e-138 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KIAEFMKN_02378 1.9e-74 yutE S Protein of unknown function DUF86
KIAEFMKN_02379 3.4e-48 yutD S protein conserved in bacteria
KIAEFMKN_02380 1.1e-172 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KIAEFMKN_02381 1.7e-195 lytH M Peptidase, M23
KIAEFMKN_02382 9.4e-127 yunB S Sporulation protein YunB (Spo_YunB)
KIAEFMKN_02383 8.2e-48 yunC S Domain of unknown function (DUF1805)
KIAEFMKN_02384 5.1e-286 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KIAEFMKN_02385 2.9e-273 sufB O FeS cluster assembly
KIAEFMKN_02386 6.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KIAEFMKN_02387 9.1e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KIAEFMKN_02388 1.4e-242 sufD O assembly protein SufD
KIAEFMKN_02389 2.7e-143 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KIAEFMKN_02391 1.6e-51 traF CO Thioredoxin
KIAEFMKN_02392 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KIAEFMKN_02393 1.3e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KIAEFMKN_02394 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KIAEFMKN_02395 6.1e-216 fadA 2.3.1.16 I Belongs to the thiolase family
KIAEFMKN_02396 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KIAEFMKN_02397 2.6e-14 S YuzL-like protein
KIAEFMKN_02398 7.4e-42
KIAEFMKN_02399 4.6e-55 yusN M Coat F domain
KIAEFMKN_02400 2.4e-204 rodA D Belongs to the SEDS family
KIAEFMKN_02401 1.9e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KIAEFMKN_02402 2.7e-282 cls2 I PLD-like domain
KIAEFMKN_02404 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KIAEFMKN_02406 8.3e-193 M1-600 T Putative diguanylate phosphodiesterase
KIAEFMKN_02407 5e-300 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KIAEFMKN_02408 4.3e-106 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KIAEFMKN_02409 5.7e-143 pgdA 3.5.1.104, 3.5.1.41 G Polysaccharide deacetylase
KIAEFMKN_02410 2.6e-244 ugtP 2.4.1.315 GT28 M Monogalactosyldiacylglycerol (MGDG) synthase
KIAEFMKN_02411 4.5e-131
KIAEFMKN_02412 1.9e-86 S Putative zinc-finger
KIAEFMKN_02413 3e-93 K Belongs to the sigma-70 factor family. ECF subfamily
KIAEFMKN_02414 6e-224 ykoN 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KIAEFMKN_02415 0.0 M Dolichyl-phosphate-mannose-protein mannosyltransferase
KIAEFMKN_02416 2.6e-260 NU cell adhesion
KIAEFMKN_02417 8.9e-184 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KIAEFMKN_02418 1.7e-179 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KIAEFMKN_02419 4.9e-167 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KIAEFMKN_02420 3.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIAEFMKN_02421 1.7e-260 yjmB G MFS/sugar transport protein
KIAEFMKN_02422 1.8e-286 uxaC 5.3.1.12 G glucuronate isomerase
KIAEFMKN_02423 1.2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KIAEFMKN_02424 5.8e-277 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KIAEFMKN_02425 8.9e-192 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
KIAEFMKN_02426 1.4e-119 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KIAEFMKN_02427 1.3e-137 K helix_turn_helix isocitrate lyase regulation
KIAEFMKN_02428 2.6e-55 S SMI1 / KNR4 family (SUKH-1)
KIAEFMKN_02429 3.1e-18
KIAEFMKN_02430 3e-248 L PFAM Transposase, IS4-like
KIAEFMKN_02431 3e-279 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KIAEFMKN_02432 2.3e-158 L Archaeal putative transposase ISC1217
KIAEFMKN_02433 1.4e-10
KIAEFMKN_02434 3.7e-18 L IS66 Orf2 like protein
KIAEFMKN_02435 7.5e-21 L Transposase IS66 family
KIAEFMKN_02436 6.8e-199 L Transposase IS66 family
KIAEFMKN_02437 1e-26 mobC K Transcriptional regulator
KIAEFMKN_02438 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KIAEFMKN_02439 9.2e-101 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
KIAEFMKN_02440 6.5e-255 hsdM 2.1.1.72 L HsdM N-terminal domain
KIAEFMKN_02442 5.9e-23 sidE D nuclear chromosome segregation
KIAEFMKN_02443 1e-98
KIAEFMKN_02444 3e-243 L PFAM transposase IS4 family protein
KIAEFMKN_02445 7.6e-89
KIAEFMKN_02446 2.2e-149 S transposase or invertase
KIAEFMKN_02447 1.6e-15 S transposase or invertase
KIAEFMKN_02449 1.1e-80 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KIAEFMKN_02450 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KIAEFMKN_02451 4.8e-142 est 3.1.1.1 S Carboxylesterase
KIAEFMKN_02452 2.5e-28 secG U Preprotein translocase subunit SecG
KIAEFMKN_02453 7.1e-242 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KIAEFMKN_02454 7.2e-302 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KIAEFMKN_02455 2.5e-122 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KIAEFMKN_02456 3.7e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KIAEFMKN_02457 9.6e-186 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KIAEFMKN_02458 1.2e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KIAEFMKN_02459 8.7e-40 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KIAEFMKN_02460 7.1e-245 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KIAEFMKN_02462 1.3e-07 S Heavy-metal-associated domain
KIAEFMKN_02463 7.4e-86 S Protein of unknown function (DUF1641)
KIAEFMKN_02465 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KIAEFMKN_02466 1.3e-31
KIAEFMKN_02468 3.2e-226 NT chemotaxis protein
KIAEFMKN_02470 7.3e-20 S transposase or invertase
KIAEFMKN_02471 3e-13 S transposase or invertase
KIAEFMKN_02472 5.4e-20 S transposase or invertase
KIAEFMKN_02473 2e-158 S transposase or invertase
KIAEFMKN_02474 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KIAEFMKN_02475 4.3e-86 uspF T Universal stress protein
KIAEFMKN_02477 2.6e-191 ykfD E Belongs to the ABC transporter superfamily
KIAEFMKN_02478 3.5e-179 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KIAEFMKN_02479 0.0 dppE E ABC transporter substrate-binding protein
KIAEFMKN_02480 6.4e-190 dppD P Belongs to the ABC transporter superfamily
KIAEFMKN_02481 9.1e-170 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIAEFMKN_02482 7.5e-161 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIAEFMKN_02483 6.2e-131 S Peptidase C26
KIAEFMKN_02484 1.9e-183 corA P Mediates influx of magnesium ions
KIAEFMKN_02485 8.8e-46 yhdB S YhdB-like protein
KIAEFMKN_02487 5.1e-278 ycgB S Stage V sporulation protein R
KIAEFMKN_02488 9.4e-186 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KIAEFMKN_02489 3.7e-136 3.2.1.18 GH33 E GDSL-like Lipase/Acylhydrolase
KIAEFMKN_02490 3.1e-77 bdbC O Required for disulfide bond formation in some proteins
KIAEFMKN_02491 2.9e-87 bdbA CO Thioredoxin
KIAEFMKN_02492 4.9e-90 yhcU S Family of unknown function (DUF5365)
KIAEFMKN_02493 3.3e-112 ykaA P Protein of unknown function DUF47
KIAEFMKN_02494 3.9e-179 pit P phosphate transporter
KIAEFMKN_02495 1.1e-103 2.3.1.128 J Acetyltransferase (GNAT) domain
KIAEFMKN_02497 9.6e-222 yhbH S Belongs to the UPF0229 family
KIAEFMKN_02498 0.0 prkA T Ser protein kinase
KIAEFMKN_02499 5.7e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KIAEFMKN_02500 1.4e-164 yhbB S Putative amidase domain
KIAEFMKN_02501 4.6e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KIAEFMKN_02502 1.3e-103 yvbG U UPF0056 membrane protein
KIAEFMKN_02503 6.6e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KIAEFMKN_02504 1.7e-84 S Rubrerythrin
KIAEFMKN_02505 2.9e-167 pip 3.4.11.5, 3.5.1.101 S Releases the N-terminal proline from various substrates
KIAEFMKN_02506 1.1e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KIAEFMKN_02507 1.9e-116 tcyB P COG0765 ABC-type amino acid transport system, permease component
KIAEFMKN_02508 4.5e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KIAEFMKN_02509 6e-149 focA P Formate/nitrite transporter
KIAEFMKN_02510 3.9e-215 dhaT 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
KIAEFMKN_02511 0.0 pflB 2.3.1.54 C formate acetyltransferase
KIAEFMKN_02512 1.7e-144 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KIAEFMKN_02513 5.8e-100 1.5.1.38 S FMN reductase
KIAEFMKN_02514 1.2e-89
KIAEFMKN_02515 2.5e-170 bcrB S ABC transporter (permease)
KIAEFMKN_02516 4.8e-168 bcrA V ABC transporter, ATP-binding protein
KIAEFMKN_02517 3.2e-144 ypmR1 E G-D-S-L family
KIAEFMKN_02518 6.2e-32
KIAEFMKN_02520 5.8e-170 S High confidence in function and specificity
KIAEFMKN_02521 2.2e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIAEFMKN_02522 7.4e-250 ykoH3 T Histidine kinase
KIAEFMKN_02523 6e-109
KIAEFMKN_02524 9.1e-253 L PFAM Transposase, IS4-like
KIAEFMKN_02525 1.7e-198 L Transposase IS4 family protein
KIAEFMKN_02526 7.9e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KIAEFMKN_02527 1.7e-58 K MarR family
KIAEFMKN_02528 1.3e-190 S PFAM Uncharacterised protein family UPF0236
KIAEFMKN_02529 4.4e-55 S PFAM Uncharacterised protein family UPF0236
KIAEFMKN_02530 2e-74 EGP Major facilitator Superfamily
KIAEFMKN_02531 5.1e-254 ydjE EGP Major facilitator superfamily
KIAEFMKN_02532 4.8e-157 yxxF EG EamA-like transporter family
KIAEFMKN_02533 3.4e-208 adhC 1.1.1.1 C Zinc-binding dehydrogenase
KIAEFMKN_02534 1.4e-198 S PFAM Uncharacterised protein family UPF0236
KIAEFMKN_02535 1.1e-55 S PFAM Uncharacterised protein family UPF0236
KIAEFMKN_02537 1e-190 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIAEFMKN_02538 3.7e-76 yetF3 K membrane
KIAEFMKN_02541 1.6e-08
KIAEFMKN_02545 8.7e-08
KIAEFMKN_02546 1.7e-07
KIAEFMKN_02554 2.6e-42
KIAEFMKN_02555 4.3e-42 S COG NOG14552 non supervised orthologous group
KIAEFMKN_02556 3.8e-162 ygxA S Nucleotidyltransferase-like
KIAEFMKN_02557 5e-57 ygzB S UPF0295 protein
KIAEFMKN_02558 6.5e-139 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
KIAEFMKN_02559 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KIAEFMKN_02560 7e-164 alsR K LysR substrate binding domain
KIAEFMKN_02561 9.8e-82 perR P Belongs to the Fur family
KIAEFMKN_02562 1.5e-100 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
KIAEFMKN_02563 1.5e-65 P Ion transport
KIAEFMKN_02564 7.3e-247 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KIAEFMKN_02565 9.2e-189 ssuA P ABC transporter substrate-binding protein
KIAEFMKN_02566 2.8e-140 P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KIAEFMKN_02567 3.8e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KIAEFMKN_02568 2.6e-112 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KIAEFMKN_02569 4.4e-220 yitG EGP Major facilitator Superfamily
KIAEFMKN_02570 6.1e-26
KIAEFMKN_02571 5.8e-13
KIAEFMKN_02572 1.1e-38 yqhV S Protein of unknown function (DUF2619)
KIAEFMKN_02573 2.4e-187 ygaE S Membrane
KIAEFMKN_02574 5.6e-150 K transcriptional
KIAEFMKN_02575 3.6e-28 sacX 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KIAEFMKN_02576 2.6e-267 L Transposase, IS4 family protein
KIAEFMKN_02577 2.2e-213 sacX 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KIAEFMKN_02578 3.2e-153 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KIAEFMKN_02579 1.1e-208 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
KIAEFMKN_02580 0.0 ygaD V ABC transporter
KIAEFMKN_02581 1.3e-104 ygaC J Belongs to the UPF0374 family
KIAEFMKN_02582 2.3e-35 ygaB S YgaB-like protein
KIAEFMKN_02583 3.3e-09 sspE S Small, acid-soluble spore protein, gamma-type
KIAEFMKN_02584 5.9e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIAEFMKN_02585 9.9e-166 gltC K Transcriptional regulator
KIAEFMKN_02586 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KIAEFMKN_02587 4.5e-285 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KIAEFMKN_02588 8.7e-201 mutY L A G-specific
KIAEFMKN_02589 1.1e-181 yfhP S membrane-bound metal-dependent
KIAEFMKN_02590 3.8e-20 sspK S reproduction
KIAEFMKN_02591 4.9e-51 yfhH S Protein of unknown function (DUF1811)
KIAEFMKN_02592 1.8e-139 recX 2.4.1.337 GT4 S Modulates RecA activity
KIAEFMKN_02594 8.5e-24 yfhD S YfhD-like protein
KIAEFMKN_02595 7.6e-146 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KIAEFMKN_02597 1.3e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KIAEFMKN_02598 4.7e-255 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpC family
KIAEFMKN_02599 4.5e-183 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KIAEFMKN_02600 1.3e-108 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KIAEFMKN_02601 2.4e-264 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KIAEFMKN_02602 8.8e-207 bacI V COG0577 ABC-type antimicrobial peptide transport system, permease component
KIAEFMKN_02603 2.1e-120 V ATPases associated with a variety of cellular activities
KIAEFMKN_02604 2.2e-188 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIAEFMKN_02606 1.1e-07
KIAEFMKN_02607 3.4e-86 S Stage II sporulation protein M
KIAEFMKN_02608 2e-126 V ABC transporter
KIAEFMKN_02610 1.4e-43 S Bacteriocin class IId cyclical uberolysin-like
KIAEFMKN_02612 0.0 XK27_10205
KIAEFMKN_02614 3.4e-61
KIAEFMKN_02615 7e-127 V AAA domain, putative AbiEii toxin, Type IV TA system
KIAEFMKN_02617 1.6e-112 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KIAEFMKN_02618 0.0 comP 2.7.13.3 T Histidine kinase
KIAEFMKN_02620 1.5e-129 ywdH 1.2.1.3, 1.2.1.71 C Belongs to the aldehyde dehydrogenase family
KIAEFMKN_02621 1.3e-212 acrA1_1 Q Male sterility protein
KIAEFMKN_02622 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KIAEFMKN_02624 2.6e-243 mcpA NT chemotaxis protein
KIAEFMKN_02625 7.3e-183 serA1 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIAEFMKN_02626 1.8e-220 dhsS 1.12.1.2 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KIAEFMKN_02627 1e-301 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIAEFMKN_02628 5.7e-178 S Phosphotransferase system, EIIC
KIAEFMKN_02629 8.2e-218 2.6.1.9 S HAD-hyrolase-like
KIAEFMKN_02630 9.3e-192 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KIAEFMKN_02631 1.6e-111 leuD 4.2.1.33, 4.2.1.35, 4.2.1.36 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KIAEFMKN_02632 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KIAEFMKN_02633 5.9e-205 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KIAEFMKN_02634 3e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KIAEFMKN_02635 3.6e-196 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KIAEFMKN_02636 1.1e-84 ilvN 2.2.1.6 E Acetolactate synthase
KIAEFMKN_02637 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KIAEFMKN_02638 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KIAEFMKN_02639 2.5e-245 braB E Component of the transport system for branched-chain amino acids
KIAEFMKN_02640 1.7e-151 T STAS domain
KIAEFMKN_02641 7.4e-244
KIAEFMKN_02643 5.1e-212 L Transposase
KIAEFMKN_02644 2.5e-15 S Ribbon-helix-helix protein, copG family
KIAEFMKN_02645 1e-57 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KIAEFMKN_02646 6.4e-103 yetJ S Belongs to the BI1 family
KIAEFMKN_02647 9.4e-219 yxjG 2.1.1.14 E Methionine synthase
KIAEFMKN_02648 1.6e-219 yhjX P Major facilitator superfamily
KIAEFMKN_02649 3.6e-137 ypdB T LytTr DNA-binding domain
KIAEFMKN_02650 0.0 ypdA 2.7.13.3 T Signal transduction histidine kinase
KIAEFMKN_02651 1.4e-197 ansA 3.5.1.1 EJ L-asparaginase
KIAEFMKN_02652 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KIAEFMKN_02653 7.4e-106 yhgD K Transcriptional regulator
KIAEFMKN_02654 4.3e-279 yhgE S YhgE Pip N-terminal domain protein
KIAEFMKN_02655 5.2e-265 S Protein of unknown function (DUF2397)
KIAEFMKN_02656 1.6e-229 S Protein of unknown function (DUF2398)
KIAEFMKN_02657 0.0 D Putative exonuclease SbcCD, C subunit
KIAEFMKN_02658 2e-252 S Protein of unknown function N-terminus (DUF3323)
KIAEFMKN_02659 5.5e-86
KIAEFMKN_02661 1.9e-194 NT chemotaxis protein
KIAEFMKN_02662 2.1e-157 yoaT S Protein of unknown function (DUF817)
KIAEFMKN_02663 1.2e-29 yozG K Transcriptional regulator
KIAEFMKN_02664 6.6e-76 yoaS S Protein of unknown function (DUF2975)
KIAEFMKN_02665 1.1e-54
KIAEFMKN_02666 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KIAEFMKN_02667 3.7e-236 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KIAEFMKN_02668 1.8e-73 yqgC S protein conserved in bacteria
KIAEFMKN_02669 4.7e-266 ydbT S Bacterial PH domain
KIAEFMKN_02670 9.4e-86 S Bacterial PH domain
KIAEFMKN_02671 1e-87 S AAA domain
KIAEFMKN_02672 5.2e-262 proP EGP Transporter
KIAEFMKN_02673 6.7e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KIAEFMKN_02674 6.9e-50 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KIAEFMKN_02675 9.1e-147 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KIAEFMKN_02676 1.3e-126 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KIAEFMKN_02677 2.3e-187 2.3.1.180 I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
KIAEFMKN_02678 2.7e-58
KIAEFMKN_02680 2.5e-250 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KIAEFMKN_02682 3e-307 lmrA 3.6.3.44 V ABC transporter
KIAEFMKN_02683 7.4e-101 K DNA-binding transcription factor activity
KIAEFMKN_02684 9.1e-68 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KIAEFMKN_02685 0.0 arsA 3.6.3.16 D Anion-transporting ATPase
KIAEFMKN_02686 5.6e-57 arsD S Arsenical resistance operon trans-acting repressor ArsD
KIAEFMKN_02687 1.3e-87 Q methyltransferase
KIAEFMKN_02688 2e-181 arsB P Sodium Bile acid symporter family
KIAEFMKN_02689 4.2e-87 padR K negative regulation of transcription, DNA-templated
KIAEFMKN_02690 3.5e-49 arsR K Helix-turn-helix domain
KIAEFMKN_02691 9.6e-36
KIAEFMKN_02692 3.3e-46 L COG2963 Transposase and inactivated derivatives
KIAEFMKN_02693 3.5e-154 L COG2801 Transposase and inactivated derivatives
KIAEFMKN_02695 5.3e-09 L COG3666 Transposase and inactivated derivatives
KIAEFMKN_02696 5.2e-113 L COG3666 Transposase and inactivated derivatives
KIAEFMKN_02697 3.4e-14
KIAEFMKN_02698 3.1e-41 S virulence-associated E family protein
KIAEFMKN_02699 2.1e-148 K BRO family, N-terminal domain
KIAEFMKN_02700 7.1e-44 2.7.7.7 L DNA polymerase
KIAEFMKN_02701 2.4e-28 L Protein of unknown function (DUF2800)
KIAEFMKN_02702 2.6e-18
KIAEFMKN_02703 2.4e-81 K DNA-directed RNA polymerase specialized sigma subunit
KIAEFMKN_02704 2.2e-28
KIAEFMKN_02705 3.9e-28 K Psort location Cytoplasmic, score
KIAEFMKN_02706 2.1e-195
KIAEFMKN_02707 2.4e-34
KIAEFMKN_02708 1.7e-277 S Uncharacterised protein conserved in bacteria (DUF2326)
KIAEFMKN_02709 0.0 2.1.1.72 L PFAM DNA methylase
KIAEFMKN_02710 0.0 3.1.21.5 L Type III restriction enzyme, res subunit
KIAEFMKN_02711 1.6e-255 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KIAEFMKN_02712 5e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KIAEFMKN_02713 3.6e-148 pdaA G deacetylase
KIAEFMKN_02714 1.5e-26 yfjT
KIAEFMKN_02715 9e-147 yfkD S YfkD-like protein
KIAEFMKN_02716 5.7e-173 cax P COG0387 Ca2 H antiporter
KIAEFMKN_02717 3.5e-219 yfkF EGP Major facilitator Superfamily
KIAEFMKN_02718 7.3e-147 yihY S Belongs to the UPF0761 family
KIAEFMKN_02719 3.3e-40 yfkK S Belongs to the UPF0435 family
KIAEFMKN_02720 2.2e-142 map 3.4.11.18 E Methionine aminopeptidase
KIAEFMKN_02721 9.2e-92 yfkM 3.5.1.124 S protease
KIAEFMKN_02722 2.1e-122 motB N Flagellar motor protein
KIAEFMKN_02723 2.8e-135 motA N flagellar motor
KIAEFMKN_02724 1e-57 yhdN S Domain of unknown function (DUF1992)
KIAEFMKN_02726 3.1e-59 yeaO S Protein of unknown function, DUF488
KIAEFMKN_02727 1.6e-227 EGP Major facilitator Superfamily
KIAEFMKN_02728 1.9e-141 dksA T COG1734 DnaK suppressor protein
KIAEFMKN_02729 3.7e-85 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KIAEFMKN_02730 2.2e-182 mreB D Rod-share determining protein MreBH
KIAEFMKN_02731 1.6e-168 yuaG S protein conserved in bacteria
KIAEFMKN_02732 1.7e-91 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KIAEFMKN_02733 6.7e-212 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KIAEFMKN_02734 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KIAEFMKN_02735 2.1e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KIAEFMKN_02736 4.2e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KIAEFMKN_02737 1.3e-102 4.2.1.1 P Reversible hydration of carbon dioxide
KIAEFMKN_02738 7.1e-124 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KIAEFMKN_02740 1.4e-297 K helix_turn_helix, Lux Regulon
KIAEFMKN_02741 3.7e-108 che
KIAEFMKN_02742 3.4e-68 S response to pH
KIAEFMKN_02743 1.6e-96
KIAEFMKN_02744 1.6e-139 ypuA S Secreted protein
KIAEFMKN_02745 1.6e-216 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KIAEFMKN_02746 7.7e-220 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KIAEFMKN_02747 5.3e-110 cobC 3.1.3.3, 3.1.3.73, 5.4.2.12 G Histidine phosphatase superfamily (branch 1)
KIAEFMKN_02749 1.7e-72 K Transcriptional
KIAEFMKN_02750 5.8e-42 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIAEFMKN_02751 1.1e-154 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIAEFMKN_02752 5.7e-94 cas4 3.1.12.1 L TIGRFAM CRISPR-associated protein Cas4
KIAEFMKN_02753 0.0 L Metal dependent phosphohydrolases with conserved 'HD' motif.
KIAEFMKN_02754 4.3e-129 cas5 L TIGRFAM CRISPR-associated protein Cas5
KIAEFMKN_02755 8.5e-184 cas7 L CRISPR-associated protein Cas7
KIAEFMKN_02756 0.0
KIAEFMKN_02757 5.8e-143 cas6 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA)
KIAEFMKN_02758 0.0 snf 2.7.11.1 L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KIAEFMKN_02759 8e-108 C Nitroreductase family
KIAEFMKN_02760 9.1e-89 1.8.5.2 S DoxX
KIAEFMKN_02761 7.8e-191 fni 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KIAEFMKN_02762 2.5e-118 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KIAEFMKN_02763 6e-35 yoeD G Helix-turn-helix domain
KIAEFMKN_02764 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KIAEFMKN_02765 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KIAEFMKN_02766 4.6e-132 fruR K Transcriptional regulator
KIAEFMKN_02767 5.9e-205 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KIAEFMKN_02768 2.1e-91 D Hemerythrin HHE cation binding
KIAEFMKN_02769 1.8e-31
KIAEFMKN_02770 2.5e-152 yidA S hydrolases of the HAD superfamily
KIAEFMKN_02771 3.5e-57 ygbA S Nitrous oxide-stimulated promoter
KIAEFMKN_02772 1.9e-211 L Transposase
KIAEFMKN_02773 1.1e-15 S Ribbon-helix-helix protein, copG family
KIAEFMKN_02774 1.7e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system
KIAEFMKN_02775 7.8e-272 iolT EGP Major facilitator Superfamily
KIAEFMKN_02776 2.8e-204 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KIAEFMKN_02778 7.6e-71 ywnF S Family of unknown function (DUF5392)
KIAEFMKN_02779 5.8e-135 ywaC 2.7.6.5 S protein conserved in bacteria
KIAEFMKN_02780 1.7e-254 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KIAEFMKN_02781 2.3e-192 yhdN C Aldo keto reductase
KIAEFMKN_02782 2e-266 L Transposase
KIAEFMKN_02783 6.8e-40 yxaD K MarR family transcriptional regulator
KIAEFMKN_02784 1.4e-47
KIAEFMKN_02785 2.1e-14
KIAEFMKN_02786 4.8e-80 K helix_turn_helix, Lux Regulon
KIAEFMKN_02787 4.2e-84 yxjM T Histidine kinase
KIAEFMKN_02788 3.2e-24
KIAEFMKN_02790 2.8e-49 icmJ L endonuclease
KIAEFMKN_02791 1e-58 ydcG S Belongs to the UPF0310 family
KIAEFMKN_02792 1.1e-48 S DinB superfamily
KIAEFMKN_02793 3.1e-125 K Transcriptional regulator
KIAEFMKN_02794 3.5e-147 6.2.1.3, 6.2.1.31 IQ AMP-binding enzyme C-terminal domain
KIAEFMKN_02795 7.6e-102 6.2.1.3, 6.2.1.31 IQ AMP-binding enzyme C-terminal domain
KIAEFMKN_02796 1.1e-212 L PFAM Transposase DDE domain
KIAEFMKN_02797 1.4e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
KIAEFMKN_02798 1.6e-100 dhaL 2.7.1.121 S Dak2
KIAEFMKN_02799 8.3e-182 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
KIAEFMKN_02800 5.6e-173 pfoS S Phosphotransferase system, EIIC
KIAEFMKN_02801 7.9e-112 ureH S PFAM Nickel cobalt transporter, high-affinity
KIAEFMKN_02802 6.9e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KIAEFMKN_02803 7.3e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KIAEFMKN_02804 3.7e-104 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KIAEFMKN_02805 6e-79 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KIAEFMKN_02806 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KIAEFMKN_02807 6.7e-56 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KIAEFMKN_02808 3.7e-48 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KIAEFMKN_02809 4e-200 amiF 3.5.1.49 S Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide
KIAEFMKN_02810 6.9e-309 F COG1457 Purine-cytosine permease and related proteins
KIAEFMKN_02811 6.3e-190 amiE 3.5.1.4 S Carbon-nitrogen hydrolase
KIAEFMKN_02812 0.0 KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KIAEFMKN_02813 3.6e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KIAEFMKN_02814 4e-240 E COG1113 Gamma-aminobutyrate permease and related permeases
KIAEFMKN_02815 9.5e-167 ytnM S membrane transporter protein
KIAEFMKN_02816 3.2e-226 ywdJ F Xanthine uracil
KIAEFMKN_02817 0.0 yjcD 3.6.4.12 L DNA helicase
KIAEFMKN_02818 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KIAEFMKN_02820 9.4e-98 O HI0933-like protein
KIAEFMKN_02823 4.1e-80 K Acetyltransferase (GNAT) domain
KIAEFMKN_02824 9.7e-291 yngE I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KIAEFMKN_02825 3.5e-135 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KIAEFMKN_02826 3.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KIAEFMKN_02827 4.8e-15 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KIAEFMKN_02828 1.5e-250 yngH 6.3.4.14, 6.3.4.6, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KIAEFMKN_02829 8e-213 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KIAEFMKN_02830 0.0 6.2.1.1 I AMP-dependent synthetase
KIAEFMKN_02831 1.2e-296 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KIAEFMKN_02832 8.4e-252 zraR KT Transcriptional regulator
KIAEFMKN_02833 2.4e-231 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KIAEFMKN_02834 6e-244 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KIAEFMKN_02835 3.8e-257 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
KIAEFMKN_02836 2e-274 hsdM 2.1.1.72 V Type I restriction-modification system
KIAEFMKN_02838 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
KIAEFMKN_02839 5e-276 lysP E amino acid
KIAEFMKN_02840 1.7e-114 K Transcriptional regulator
KIAEFMKN_02841 1.2e-201 ybhR V COG0842 ABC-type multidrug transport system, permease component
KIAEFMKN_02843 1.5e-127 V COG1131 ABC-type multidrug transport system, ATPase component
KIAEFMKN_02844 8e-70 S Hemerythrin HHE cation binding domain
KIAEFMKN_02845 4.6e-51
KIAEFMKN_02846 1.9e-43
KIAEFMKN_02847 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KIAEFMKN_02848 6.6e-308 narH 1.7.5.1 C Nitrate reductase, beta
KIAEFMKN_02849 1.8e-99 narJ C nitrate reductase molybdenum cofactor assembly chaperone
KIAEFMKN_02850 8.8e-122 narI 1.7.5.1 C nitrate reductase, gamma subunit
KIAEFMKN_02851 9.6e-206 narT P COG2223 Nitrate nitrite transporter
KIAEFMKN_02852 3e-162 fda 4.1.2.13 G Belongs to the class I fructose-bisphosphate aldolase family
KIAEFMKN_02853 5.6e-72 K DeoR C terminal sensor domain
KIAEFMKN_02854 6.3e-13 K DeoR C terminal sensor domain
KIAEFMKN_02855 7.2e-59 rpiB 5.3.1.34, 5.3.1.6 G Ribose/Galactose Isomerase
KIAEFMKN_02856 4.7e-96 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KIAEFMKN_02857 4.8e-113 glpX 2.2.1.1, 3.1.3.11, 3.1.3.37 G Bacterial fructose-1,6-bisphosphatase, glpX-encoded
KIAEFMKN_02858 2e-83 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 S Dak2
KIAEFMKN_02859 2e-159 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
KIAEFMKN_02860 1e-192 yoaB EGP Major Facilitator Superfamily
KIAEFMKN_02861 7.5e-192 1.1.1.14 E Dehydrogenase
KIAEFMKN_02862 7.2e-117 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIAEFMKN_02863 8.6e-76
KIAEFMKN_02864 4e-54
KIAEFMKN_02865 1.5e-160 galM 5.1.3.3 G Aldose 1-epimerase
KIAEFMKN_02866 2e-107
KIAEFMKN_02867 4.7e-53 D SMC domain-containing protein
KIAEFMKN_02868 0.0 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KIAEFMKN_02870 5e-51
KIAEFMKN_02872 1.9e-116 S LXG domain of WXG superfamily
KIAEFMKN_02873 7.8e-82 yokK S SMI1-KNR4 cell-wall
KIAEFMKN_02874 1.6e-29 S LXG domain of WXG superfamily
KIAEFMKN_02875 1.8e-69 S Protein of unknown function, DUF600
KIAEFMKN_02876 5.1e-16
KIAEFMKN_02877 1.8e-198 mcrC V McrBC 5-methylcytosine restriction system component
KIAEFMKN_02878 0.0 mcrB V AAA domain (dynein-related subfamily)
KIAEFMKN_02879 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KIAEFMKN_02880 1.5e-89 3.1.21.3 V Type I restriction modification DNA specificity domain
KIAEFMKN_02881 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
KIAEFMKN_02882 2e-26
KIAEFMKN_02883 9.7e-115 E LysE type translocator
KIAEFMKN_02884 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KIAEFMKN_02885 4.1e-81 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KIAEFMKN_02887 9.1e-98 3.2.1.122, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KIAEFMKN_02888 4e-206 L PFAM Transposase, IS4-like
KIAEFMKN_02889 3.6e-84 S YqcI/YcgG family
KIAEFMKN_02890 2.5e-98 L Integrase
KIAEFMKN_02891 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KIAEFMKN_02892 1.1e-62 K transcriptional
KIAEFMKN_02893 1.3e-23 ymbI L Transposase
KIAEFMKN_02894 3.9e-96 S HTH-like domain
KIAEFMKN_02895 9.4e-91 nrdG 1.97.1.4 O 4Fe-4S single cluster domain
KIAEFMKN_02896 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KIAEFMKN_02897 2.8e-207 U protein localization to endoplasmic reticulum
KIAEFMKN_02898 2.2e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KIAEFMKN_02899 8e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KIAEFMKN_02900 1.5e-211 L Transposase
KIAEFMKN_02901 5.1e-212 L Transposase
KIAEFMKN_02902 1.1e-15 S Ribbon-helix-helix protein, copG family
KIAEFMKN_02903 1.8e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KIAEFMKN_02904 1.4e-149 rbsC G Belongs to the binding-protein-dependent transport system permease family
KIAEFMKN_02905 1.5e-280 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KIAEFMKN_02906 1.4e-68 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KIAEFMKN_02907 1.1e-156 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KIAEFMKN_02908 8.9e-198 rbsR K transcriptional
KIAEFMKN_02910 1.7e-12 S transposase or invertase
KIAEFMKN_02912 1.4e-159 S transposase or invertase
KIAEFMKN_02913 9e-89 1.4.3.5 S Pyridoxamine 5'phosphate oxidase-like, FMN-binding
KIAEFMKN_02914 7.2e-08 S transposase or invertase
KIAEFMKN_02915 2.9e-163 S transposase or invertase
KIAEFMKN_02916 1.1e-107 ycnI S Domain of unkown function (DUF1775)
KIAEFMKN_02917 0.0 ycnJ P protein, homolog of Cu resistance protein CopC
KIAEFMKN_02918 4.7e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KIAEFMKN_02919 6.7e-130 5.1.3.1 G Ribulose-phosphate 3 epimerase family
KIAEFMKN_02920 1.1e-178 rbsR K transcriptional
KIAEFMKN_02921 2.6e-256 G PTS system sugar-specific permease component
KIAEFMKN_02922 3.9e-51
KIAEFMKN_02924 3.4e-231 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KIAEFMKN_02925 1.5e-217 2.3.1.179 IQ Beta-ketoacyl synthase, C-terminal domain
KIAEFMKN_02926 1.3e-28 cspL K Cold shock
KIAEFMKN_02927 1.3e-73 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KIAEFMKN_02928 1.7e-75 1.14.11.21, 1.14.11.39, 1.14.11.40 C Taurine catabolism dioxygenase TauD, TfdA family
KIAEFMKN_02929 6e-145 G Major Facilitator Superfamily
KIAEFMKN_02931 9e-162 ydcZ S Putative inner membrane exporter, YdcZ
KIAEFMKN_02932 0.0 nagA 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KIAEFMKN_02933 0.0 ampC V Belongs to the UPF0214 family
KIAEFMKN_02934 3.8e-240 ybbC 3.2.1.52 S protein conserved in bacteria
KIAEFMKN_02936 6.3e-75
KIAEFMKN_02937 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KIAEFMKN_02938 0.0 yfiB V ABC transporter
KIAEFMKN_02939 7.2e-80 K helix_turn_helix multiple antibiotic resistance protein
KIAEFMKN_02940 3.2e-109 3.1.3.18 S Haloacid dehalogenase-like hydrolase
KIAEFMKN_02941 8e-246 L PFAM Transposase, IS4-like
KIAEFMKN_02942 1e-105 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KIAEFMKN_02943 1.5e-60 QT Purine catabolism regulatory protein-like family
KIAEFMKN_02944 3.1e-83 QT Purine catabolism regulatory protein-like family
KIAEFMKN_02945 9.7e-08 QT Purine catabolism regulatory protein-like family
KIAEFMKN_02946 1.8e-191 lys1 E Saccharopine dehydrogenase
KIAEFMKN_02947 1.5e-72 S Protein of unknown function (DUF3237)
KIAEFMKN_02948 2.6e-293 estC CE10 I Belongs to the type-B carboxylesterase lipase family
KIAEFMKN_02949 2.7e-171 3.5.1.4 J Belongs to the amidase family
KIAEFMKN_02950 8.2e-48 3.5.1.4 J Belongs to the amidase family
KIAEFMKN_02951 5.3e-181 EGP Major facilitator Superfamily
KIAEFMKN_02952 1.3e-172 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KIAEFMKN_02953 2.8e-75 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KIAEFMKN_02954 6.3e-122 S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
KIAEFMKN_02955 9.8e-173 2.6.1.113 H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KIAEFMKN_02956 4.5e-107 P Integral membrane protein TerC family
KIAEFMKN_02957 1.5e-30 S Domain of unknown function (DUF202)
KIAEFMKN_02959 1.3e-144 XK27_04815 S Membrane transport protein
KIAEFMKN_02960 2.3e-270 L RNA-directed DNA polymerase (reverse transcriptase)
KIAEFMKN_02961 1.1e-305 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KIAEFMKN_02962 6.4e-24 S Uncharacterized small protein (DUF2292)
KIAEFMKN_02963 1.4e-95 ssuE 1.5.1.38 S FMN reductase
KIAEFMKN_02964 5.1e-139 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
KIAEFMKN_02965 1.4e-136 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KIAEFMKN_02966 6.3e-218 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KIAEFMKN_02967 1.8e-168 P ABC transporter substrate-binding protein
KIAEFMKN_02968 1e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KIAEFMKN_02970 5.8e-85 S SMI1-KNR4 cell-wall
KIAEFMKN_02971 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KIAEFMKN_02972 2e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KIAEFMKN_02973 1.3e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KIAEFMKN_02974 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KIAEFMKN_02975 3.6e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KIAEFMKN_02976 6.7e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KIAEFMKN_02977 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KIAEFMKN_02978 4.9e-213 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KIAEFMKN_02979 1.9e-218 pbuO_1 S permease
KIAEFMKN_02980 1.8e-116 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KIAEFMKN_02981 8e-166 S Protein of unknown function (DUF979)
KIAEFMKN_02982 6.5e-117 S Protein of unknown function (DUF969)
KIAEFMKN_02983 2.6e-135 ycsF S Belongs to the UPF0271 (lamB) family
KIAEFMKN_02984 5.4e-181 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KIAEFMKN_02985 3.2e-135 kipI 3.5.1.54, 6.3.4.6 E Allophanate hydrolase subunit 1
KIAEFMKN_02986 1.2e-214 EGP Major facilitator Superfamily
KIAEFMKN_02987 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
KIAEFMKN_02988 3.7e-131 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KIAEFMKN_02989 7.6e-115 artQ E COG0765 ABC-type amino acid transport system, permease component
KIAEFMKN_02990 2e-135 artP ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KIAEFMKN_02991 2.6e-219 hipO3 3.5.1.47 S amidohydrolase
KIAEFMKN_02992 0.0 htpG O Molecular chaperone. Has ATPase activity
KIAEFMKN_02993 4.8e-207 M FFAT motif binding
KIAEFMKN_02994 2.8e-57 I Domain of unknown function (DUF4430)
KIAEFMKN_02995 3.7e-94 S Psort location CytoplasmicMembrane, score
KIAEFMKN_02997 3.6e-29
KIAEFMKN_02998 1.5e-91 E Zn peptidase
KIAEFMKN_02999 2.3e-63
KIAEFMKN_03000 1.3e-113 crtF 2.1.1.210, 2.1.1.281, 2.1.1.79 M Methyltransferase
KIAEFMKN_03001 2.1e-210 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KIAEFMKN_03002 3e-34 S Protein of unknown function DUF86
KIAEFMKN_03003 1.8e-41 S Nucleotidyltransferase domain
KIAEFMKN_03004 1.7e-190 adhP 1.1.1.1 C alcohol dehydrogenase
KIAEFMKN_03006 7.4e-85 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIAEFMKN_03007 2.7e-40 S Protein of unknown function (DUF2750)
KIAEFMKN_03008 2.2e-24 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KIAEFMKN_03009 6.5e-112 EGP Major facilitator Superfamily
KIAEFMKN_03010 8.5e-142 IQ Enoyl-(Acyl carrier protein) reductase
KIAEFMKN_03011 5.5e-147 S Protein of unknown function
KIAEFMKN_03012 2.3e-141 S Protein of unknown function (DUF2961)
KIAEFMKN_03013 0.0 L Domain of unknown function (DUF4277)
KIAEFMKN_03014 2.5e-73 3.2.1.20 GH31 S Protein of unknown function (DUF2961)
KIAEFMKN_03015 0.0
KIAEFMKN_03016 2.7e-174 L PFAM Transposase, IS4-like
KIAEFMKN_03017 6.9e-253 L PFAM Transposase, IS4-like
KIAEFMKN_03018 5.7e-94 S S4 RNA-binding domain
KIAEFMKN_03019 1e-53 3.5.1.19 Q Isochorismatase family
KIAEFMKN_03021 1.5e-09 L DDE superfamily endonuclease
KIAEFMKN_03022 2.4e-42 K Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KIAEFMKN_03023 3e-248 L PFAM Transposase, IS4-like
KIAEFMKN_03024 1.2e-266 K PTS system fructose IIA component
KIAEFMKN_03025 3.2e-107 K PFAM sigma-54 factor interaction domain-containing protein
KIAEFMKN_03026 1.2e-71 2.7.1.191 G PTS system fructose IIA component
KIAEFMKN_03027 9.7e-83 2.7.1.191 G PTS system sorbose subfamily IIB component
KIAEFMKN_03028 1e-129 G PTS system sorbose-specific iic component
KIAEFMKN_03029 1e-145 G PFAM Phosphotransferase system, mannose fructose sorbose family IID component
KIAEFMKN_03030 4.3e-49
KIAEFMKN_03031 1.6e-63 L PFAM Transposase, IS4-like
KIAEFMKN_03032 6.9e-253 L PFAM Transposase, IS4-like
KIAEFMKN_03033 3.7e-185
KIAEFMKN_03034 8.1e-51 yxjI S LURP-one-related
KIAEFMKN_03035 2.2e-265 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KIAEFMKN_03036 4.6e-269 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KIAEFMKN_03037 4.2e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KIAEFMKN_03038 1.4e-155 Q N-acetyltransferase
KIAEFMKN_03041 3.9e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KIAEFMKN_03042 1.1e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KIAEFMKN_03043 1.5e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KIAEFMKN_03044 1.9e-245 aceA 4.1.3.1 C Isocitrate lyase
KIAEFMKN_03045 0.0 aceB 2.3.3.9 C Belongs to the malate synthase family
KIAEFMKN_03046 2e-219 camS S COG4851 Protein involved in sex pheromone biosynthesis
KIAEFMKN_03047 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KIAEFMKN_03048 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KIAEFMKN_03049 6.7e-130 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KIAEFMKN_03050 7.1e-53 yerC S protein conserved in bacteria
KIAEFMKN_03051 3.8e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
KIAEFMKN_03052 0.0 yerA 3.5.4.2 F adenine deaminase
KIAEFMKN_03053 4.2e-36 S Protein of unknown function (DUF2892)
KIAEFMKN_03054 9e-226 purD 6.3.4.13 F Belongs to the GARS family
KIAEFMKN_03055 6.1e-285 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KIAEFMKN_03056 1.1e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KIAEFMKN_03057 4.8e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KIAEFMKN_03058 4.7e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KIAEFMKN_03059 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KIAEFMKN_03060 6.8e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KIAEFMKN_03061 9e-40 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KIAEFMKN_03062 2.1e-126 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KIAEFMKN_03063 1.1e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KIAEFMKN_03064 9.9e-219 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KIAEFMKN_03065 1.1e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KIAEFMKN_03066 5.4e-30 yebG S NETI protein
KIAEFMKN_03067 3.1e-90 yebE S UPF0316 protein
KIAEFMKN_03068 5.4e-130 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KIAEFMKN_03069 4.3e-21 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
KIAEFMKN_03071 1.7e-41
KIAEFMKN_03072 4.3e-42 S COG NOG14552 non supervised orthologous group
KIAEFMKN_03073 7.9e-222 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KIAEFMKN_03074 0.0 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KIAEFMKN_03075 2.5e-155 glcT K antiterminator
KIAEFMKN_03076 4.7e-233 pbuG S permease
KIAEFMKN_03078 0.0 ywjA V ABC transporter
KIAEFMKN_03079 1.7e-213 ynfM EGP Major facilitator Superfamily
KIAEFMKN_03080 4.7e-117 yfiK K Regulator
KIAEFMKN_03081 2.7e-197 T Histidine kinase
KIAEFMKN_03082 5.8e-169 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
KIAEFMKN_03083 1.9e-198 yfiM V ABC-2 type transporter
KIAEFMKN_03084 1.2e-205 yfiN V COG0842 ABC-type multidrug transport system, permease component
KIAEFMKN_03085 1.5e-224 1.13.11.4 Q Cupin domain
KIAEFMKN_03086 2.5e-86 S DinB superfamily
KIAEFMKN_03087 4.5e-177 3.7.1.5 Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KIAEFMKN_03088 7.3e-141 K helix_turn_helix isocitrate lyase regulation
KIAEFMKN_03089 2.1e-151 benK EGP Major facilitator Superfamily
KIAEFMKN_03090 7.9e-09 S PD-(D/E)XK nuclease family transposase
KIAEFMKN_03091 5.5e-55 S PD-(D/E)XK nuclease family transposase
KIAEFMKN_03092 1.2e-164 6.2.1.30 H AMP-binding enzyme C-terminal domain
KIAEFMKN_03093 1.1e-101
KIAEFMKN_03094 2.2e-155 1.14.13.127 CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KIAEFMKN_03095 2.7e-70 ysmA 3.1.2.23 S Thioesterase-like superfamily
KIAEFMKN_03096 1.5e-305 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KIAEFMKN_03097 1e-215 bktB 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
KIAEFMKN_03098 2e-138 4.2.1.17 I Enoyl-CoA hydratase/isomerase
KIAEFMKN_03099 2.9e-154 hbd 1.1.1.157 I Dehydrogenase
KIAEFMKN_03100 2.3e-176 cyaD 2.7.11.1, 3.1.4.52, 4.6.1.1 QT Domain present in phytochromes and cGMP-specific phosphodiesterases.
KIAEFMKN_03101 4e-211 benK EGP Major facilitator Superfamily
KIAEFMKN_03102 9.3e-254 ybhI P Sodium:sulfate symporter transmembrane region
KIAEFMKN_03103 1.5e-87 endA 3.1.21.1 L Endonuclease I
KIAEFMKN_03104 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
KIAEFMKN_03107 3.9e-164 tnp4 L Transposase, Mutator family
KIAEFMKN_03109 2e-128
KIAEFMKN_03110 9e-122 yhcG V ABC transporter, ATP-binding protein
KIAEFMKN_03111 3.1e-57 yhcF K Transcriptional regulator
KIAEFMKN_03112 1.1e-93 padR K transcriptional
KIAEFMKN_03113 2.1e-96 padC Q Phenolic acid decarboxylase
KIAEFMKN_03114 1.2e-112 ywnB S NAD(P)H-binding
KIAEFMKN_03115 9.9e-71 ywnA K Transcriptional regulator
KIAEFMKN_03116 1.1e-89 prrC P ABC transporter
KIAEFMKN_03117 9.9e-92 S ABC-2 family transporter protein
KIAEFMKN_03118 8.8e-248 L PFAM Transposase, IS4-like
KIAEFMKN_03119 1.1e-31 rcfB K Bacterial regulatory proteins, crp family
KIAEFMKN_03120 1.5e-15 yeeD O Belongs to the sulfur carrier protein TusA family
KIAEFMKN_03121 4e-24 yeeE S Sulphur transport
KIAEFMKN_03122 3.7e-279 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KIAEFMKN_03123 9.8e-64 argO S Lysine exporter protein LysE YggA
KIAEFMKN_03124 1.1e-14 S transposase or invertase
KIAEFMKN_03125 1.4e-13 S transposase or invertase
KIAEFMKN_03126 3.5e-133 S transposase or invertase
KIAEFMKN_03127 1.6e-09 S transposase or invertase
KIAEFMKN_03128 6.9e-36 yeeD O Belongs to the sulfur carrier protein TusA family
KIAEFMKN_03129 6.5e-193 yeeE S Sulphur transport
KIAEFMKN_03130 6.6e-242 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KIAEFMKN_03131 6.4e-173 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIAEFMKN_03132 1.7e-07
KIAEFMKN_03133 6.3e-30 ybxH S Family of unknown function (DUF5370)
KIAEFMKN_03134 1.9e-189 P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KIAEFMKN_03135 3.3e-138 fecE 3.6.3.34 HP ABC transporter
KIAEFMKN_03136 9e-174 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIAEFMKN_03137 3.1e-93
KIAEFMKN_03139 5.4e-184 emrB P Major facilitator superfamily
KIAEFMKN_03140 8.6e-12 EGP Major facilitator superfamily
KIAEFMKN_03141 1.3e-28 K Helix-turn-helix domain
KIAEFMKN_03142 4.7e-31
KIAEFMKN_03143 9.1e-32 S Domain of unknown function (DUF4177)
KIAEFMKN_03144 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KIAEFMKN_03145 1.4e-153 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KIAEFMKN_03146 5.5e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KIAEFMKN_03147 3.4e-108 pncA Q COG1335 Amidases related to nicotinamidase
KIAEFMKN_03148 4.7e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KIAEFMKN_03149 0.0 ykoS
KIAEFMKN_03150 1.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KIAEFMKN_03151 2e-67 yngA S GtrA-like protein
KIAEFMKN_03152 5.3e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KIAEFMKN_03153 9.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KIAEFMKN_03154 8.1e-126 ydiL S CAAX protease self-immunity
KIAEFMKN_03155 1.3e-27 S Domain of unknown function (DUF4305)
KIAEFMKN_03156 5.1e-131 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KIAEFMKN_03157 2.7e-123 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KIAEFMKN_03158 1.6e-08 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KIAEFMKN_03159 0.0 ydiF S ABC transporter
KIAEFMKN_03160 8.9e-184 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KIAEFMKN_03161 4.5e-82 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KIAEFMKN_03162 1.7e-128 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KIAEFMKN_03163 9e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KIAEFMKN_03165 1.7e-41
KIAEFMKN_03166 4.3e-42 S COG NOG14552 non supervised orthologous group
KIAEFMKN_03171 1.6e-08
KIAEFMKN_03179 5.1e-92 ydcK S Belongs to the SprT family
KIAEFMKN_03180 0.0 yhgF K COG2183 Transcriptional accessory protein
KIAEFMKN_03181 8.6e-110 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KIAEFMKN_03182 1.3e-137 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KIAEFMKN_03183 2.3e-81 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KIAEFMKN_03184 3.6e-61 rsbV T Belongs to the anti-sigma-factor antagonist family
KIAEFMKN_03185 6.4e-190 rsbU 3.1.3.3 KT phosphatase
KIAEFMKN_03186 2e-70 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KIAEFMKN_03187 2.1e-55 rsbS T antagonist
KIAEFMKN_03188 3e-153 rsbR T Positive regulator of sigma-B
KIAEFMKN_03189 7.2e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KIAEFMKN_03190 2e-40 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KIAEFMKN_03191 1.7e-218 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KIAEFMKN_03192 8.4e-190 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KIAEFMKN_03193 1.2e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KIAEFMKN_03194 3.8e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KIAEFMKN_03195 1.7e-260 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KIAEFMKN_03196 7.1e-59
KIAEFMKN_03197 5.5e-107 E Lysine exporter protein LysE YggA
KIAEFMKN_03198 4.4e-118 otsB2 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KIAEFMKN_03199 2.9e-176 yvdE K Transcriptional regulator
KIAEFMKN_03200 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KIAEFMKN_03201 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
KIAEFMKN_03202 1.1e-242 mdxE G COG2182 Maltose-binding periplasmic proteins domains
KIAEFMKN_03203 2.2e-243 malC P COG1175 ABC-type sugar transport systems, permease components
KIAEFMKN_03204 5.1e-156 malD P transport
KIAEFMKN_03205 1.5e-147 malA S Protein of unknown function (DUF1189)
KIAEFMKN_03206 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KIAEFMKN_03207 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KIAEFMKN_03208 2.9e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KIAEFMKN_03209 1.1e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KIAEFMKN_03210 2.1e-148
KIAEFMKN_03211 2.7e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KIAEFMKN_03212 7.8e-82 cueR K transcriptional
KIAEFMKN_03213 1.7e-249 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KIAEFMKN_03215 1.4e-278 S PFAM Uncharacterised protein family UPF0236
KIAEFMKN_03216 4.9e-309 ywqB S Zinc finger, swim domain protein
KIAEFMKN_03217 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KIAEFMKN_03218 3.3e-71 ywpF S YwpF-like protein
KIAEFMKN_03219 1.3e-63 ssbB L Single-stranded DNA-binding protein
KIAEFMKN_03221 3.5e-73 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KIAEFMKN_03222 5.5e-147 flhP N flagellar basal body
KIAEFMKN_03223 4.9e-145 flhO N flagellar basal body
KIAEFMKN_03224 1e-179 mbl D Rod shape-determining protein
KIAEFMKN_03225 1.3e-41 spoIIID K Stage III sporulation protein D
KIAEFMKN_03226 7.7e-127 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KIAEFMKN_03227 1.4e-184 spoIID D Stage II sporulation protein D
KIAEFMKN_03228 8.8e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KIAEFMKN_03229 2.5e-135 ywmB S TATA-box binding
KIAEFMKN_03230 1.4e-34 ywzB S membrane
KIAEFMKN_03231 6.3e-59 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KIAEFMKN_03232 2.7e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KIAEFMKN_03233 5e-151 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KIAEFMKN_03234 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KIAEFMKN_03235 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KIAEFMKN_03236 1e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KIAEFMKN_03237 1.3e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KIAEFMKN_03238 8.2e-131 atpB C it plays a direct role in the translocation of protons across the membrane
KIAEFMKN_03239 4.1e-57 atpI S ATP synthase I chain
KIAEFMKN_03240 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KIAEFMKN_03241 1.1e-239 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KIAEFMKN_03242 6.1e-97 ywlG S Belongs to the UPF0340 family
KIAEFMKN_03243 1.4e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KIAEFMKN_03244 8.8e-176 mcpA NT Chemotaxis
KIAEFMKN_03245 2.4e-80 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KIAEFMKN_03246 3.7e-91 mntP P Probably functions as a manganese efflux pump
KIAEFMKN_03247 6.3e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KIAEFMKN_03248 7.4e-122 spoIIR S stage II sporulation protein R
KIAEFMKN_03249 6.3e-162 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KIAEFMKN_03250 6.6e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KIAEFMKN_03251 9e-07
KIAEFMKN_03252 1.7e-110 tdk 2.7.1.21 F thymidine kinase
KIAEFMKN_03253 2.2e-33 rpmE J Ribosomal protein L31
KIAEFMKN_03254 2.7e-230 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KIAEFMKN_03255 7.8e-177 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KIAEFMKN_03256 5.6e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KIAEFMKN_03257 4.4e-115 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KIAEFMKN_03258 3.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KIAEFMKN_03259 6e-61 spo0F T response regulator
KIAEFMKN_03260 5.4e-217
KIAEFMKN_03261 8.9e-145
KIAEFMKN_03262 4.6e-123 yhcG V ABC transporter, ATP-binding protein
KIAEFMKN_03263 1e-66 K helix_turn_helix gluconate operon transcriptional repressor
KIAEFMKN_03264 2.2e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KIAEFMKN_03265 2.7e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KIAEFMKN_03266 9.2e-124 V ATPases associated with a variety of cellular activities
KIAEFMKN_03267 0.0 S FtsX-like permease family
KIAEFMKN_03268 0.0 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KIAEFMKN_03269 2.6e-112 kstR2_2 K Transcriptional regulator
KIAEFMKN_03270 3.2e-214 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
KIAEFMKN_03271 3.7e-210 mmgC I acyl-CoA dehydrogenase
KIAEFMKN_03272 2.9e-218 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
KIAEFMKN_03273 0.0 fadF C COG0247 Fe-S oxidoreductase
KIAEFMKN_03274 7.8e-219 cls I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KIAEFMKN_03275 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KIAEFMKN_03276 8.7e-75 ywiB S protein conserved in bacteria
KIAEFMKN_03277 4.1e-169 speB 3.5.3.11 E Belongs to the arginase family
KIAEFMKN_03278 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KIAEFMKN_03279 3.1e-92 ywhD S YwhD family
KIAEFMKN_03280 1.7e-119 ywhC S Peptidase M50
KIAEFMKN_03281 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KIAEFMKN_03282 3.3e-89 ywgA 2.1.1.72, 3.1.21.3
KIAEFMKN_03283 6.1e-257 ywfO S COG1078 HD superfamily phosphohydrolases
KIAEFMKN_03284 6.3e-99 rsfA S Transcriptional regulator
KIAEFMKN_03285 6.1e-154 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KIAEFMKN_03286 3e-176 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KIAEFMKN_03287 3.3e-146 ywfI C May function as heme-dependent peroxidase
KIAEFMKN_03288 1e-58 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KIAEFMKN_03289 2.8e-58 ywdK S small membrane protein
KIAEFMKN_03290 1.9e-34 S Family of unknown function (DUF5327)
KIAEFMKN_03291 3.8e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KIAEFMKN_03292 3.3e-53 S Heat induced stress protein YflT
KIAEFMKN_03294 3.9e-158 L Archaeal putative transposase ISC1217
KIAEFMKN_03295 3.5e-19 S Circ_ocin_uber circular bacteriocin, circularin A uberolysin family protein
KIAEFMKN_03296 2.1e-291
KIAEFMKN_03297 2.7e-43 S Stage II sporulation protein M
KIAEFMKN_03298 2.8e-120 V ATPases associated with a variety of cellular activities
KIAEFMKN_03301 8.6e-248 L PFAM Transposase, IS4-like
KIAEFMKN_03302 6.2e-151 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KIAEFMKN_03303 5.7e-61 yojF S Protein of unknown function (DUF1806)
KIAEFMKN_03304 1.6e-128 bshB2 S deacetylase
KIAEFMKN_03305 9.8e-163 ycsE S hydrolases of the HAD superfamily
KIAEFMKN_03306 0.0 recQ 3.6.4.12 L DNA helicase
KIAEFMKN_03307 1e-229 phoA 3.1.3.1 P Belongs to the alkaline phosphatase family
KIAEFMKN_03308 1.5e-152 ybbH_2 K Transcriptional regulator
KIAEFMKN_03309 1e-159 S Alpha/beta hydrolase of unknown function (DUF915)
KIAEFMKN_03310 5.9e-14
KIAEFMKN_03311 5.5e-107 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KIAEFMKN_03313 1.3e-117 ywbG M effector of murein hydrolase
KIAEFMKN_03314 6.6e-55 ywbH S LrgA family
KIAEFMKN_03315 9.9e-177 ywbI K Transcriptional regulator
KIAEFMKN_03316 0.0 asnO 6.3.5.4 E Asparagine synthase
KIAEFMKN_03317 1.2e-127 S Protein of unknown function (DUF1646)
KIAEFMKN_03319 1.3e-257 L Transposase
KIAEFMKN_03320 8.8e-75 S Threonine/Serine exporter, ThrE
KIAEFMKN_03321 1.9e-130 thrE S Putative threonine/serine exporter
KIAEFMKN_03322 2.1e-207 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KIAEFMKN_03323 0.0 cstA T Carbon starvation protein
KIAEFMKN_03324 5.1e-125 lytT T COG3279 Response regulator of the LytR AlgR family
KIAEFMKN_03325 0.0 lytS 2.7.13.3 T Histidine kinase
KIAEFMKN_03326 8.7e-140 metQ M Belongs to the nlpA lipoprotein family
KIAEFMKN_03327 6.2e-101 metI P COG2011 ABC-type metal ion transport system, permease component
KIAEFMKN_03328 5.4e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KIAEFMKN_03329 5.6e-141 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KIAEFMKN_03330 1.1e-98
KIAEFMKN_03331 2.8e-221 pilM NU Pilus assembly protein
KIAEFMKN_03332 2.2e-238 yisQ V Mate efflux family protein
KIAEFMKN_03333 3.3e-149 M Glycosyl transferase family 8
KIAEFMKN_03334 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KIAEFMKN_03337 4.5e-272 EGP Major facilitator Superfamily
KIAEFMKN_03338 1.8e-248 L PFAM Transposase, IS4-like
KIAEFMKN_03339 7.1e-226 uraA F Xanthine uracil
KIAEFMKN_03340 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KIAEFMKN_03341 2.1e-126 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KIAEFMKN_03342 3.5e-300 msbA2 3.6.3.44 V ABC transporter
KIAEFMKN_03343 3.2e-113 yhhQ_2 S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KIAEFMKN_03344 2.9e-98 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KIAEFMKN_03345 0.0 S MMPL domain protein
KIAEFMKN_03346 8.2e-303 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KIAEFMKN_03347 1.3e-41 T diguanylate cyclase activity
KIAEFMKN_03348 1.9e-135 gntR2 K UTRA
KIAEFMKN_03349 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KIAEFMKN_03350 5.8e-163 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KIAEFMKN_03351 2.9e-237 LYS1 1.5.1.7 E Saccharopine dehydrogenase
KIAEFMKN_03352 1.3e-223 nspC 4.1.1.96 E Pyridoxal-dependent decarboxylase, C-terminal sheet domain
KIAEFMKN_03353 6.2e-207 S Domain of unknown function (DUF1611_N) Rossmann-like domain
KIAEFMKN_03354 1e-215 5.1.1.12 E Alanine racemase, N-terminal domain
KIAEFMKN_03355 5.4e-142 cjaA ET Belongs to the bacterial solute-binding protein 3 family
KIAEFMKN_03356 2.2e-131 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
KIAEFMKN_03357 2.6e-102 E amino acid ABC transporter
KIAEFMKN_03358 4.4e-115 papP E amino acid ABC transporter
KIAEFMKN_03359 1.5e-291 mqo 1.1.5.4 S malate quinone oxidoreductase
KIAEFMKN_03360 9.2e-245 kgtP EGP -transporter
KIAEFMKN_03361 2.3e-167 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
KIAEFMKN_03362 2.7e-137 yvfS V COG0842 ABC-type multidrug transport system, permease component
KIAEFMKN_03363 4.7e-205 desK 2.7.13.3 T Histidine kinase
KIAEFMKN_03364 1.1e-104 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KIAEFMKN_03365 4.4e-61 K PadR family transcriptional regulator
KIAEFMKN_03366 1.9e-21 S Protein of unknown function (DUF1048)
KIAEFMKN_03367 5.1e-40 S Protein of unknown function (DUF1048)
KIAEFMKN_03368 7e-78 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KIAEFMKN_03369 1.3e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KIAEFMKN_03370 8.5e-145 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KIAEFMKN_03371 1.7e-142 yycI S protein conserved in bacteria
KIAEFMKN_03372 1.9e-247 yycH S protein conserved in bacteria
KIAEFMKN_03373 0.0 vicK 2.7.13.3 T Histidine kinase
KIAEFMKN_03374 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIAEFMKN_03377 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KIAEFMKN_03378 3.7e-249 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KIAEFMKN_03379 1.2e-71 rplI J binds to the 23S rRNA
KIAEFMKN_03380 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KIAEFMKN_03381 3.6e-150 yybS S membrane
KIAEFMKN_03382 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KIAEFMKN_03383 1.5e-86 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KIAEFMKN_03384 5e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KIAEFMKN_03385 9.6e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KIAEFMKN_03386 2.2e-221 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KIAEFMKN_03387 2.6e-115 ribE 2.5.1.9 H Riboflavin synthase
KIAEFMKN_03388 2e-208 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KIAEFMKN_03389 5.9e-205 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KIAEFMKN_03390 4.2e-32 yyzM S protein conserved in bacteria
KIAEFMKN_03391 2.2e-160 ykuT M Mechanosensitive ion channel
KIAEFMKN_03392 3.3e-112 yyaC S Sporulation protein YyaC
KIAEFMKN_03393 6.2e-118 ydfK S Protein of unknown function (DUF554)
KIAEFMKN_03394 2.7e-149 spo0J K Belongs to the ParB family
KIAEFMKN_03395 2.6e-135 soj D COG1192 ATPases involved in chromosome partitioning
KIAEFMKN_03396 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KIAEFMKN_03397 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KIAEFMKN_03398 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KIAEFMKN_03399 1.7e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KIAEFMKN_03400 1.2e-109 jag S single-stranded nucleic acid binding R3H
KIAEFMKN_03401 4.2e-128 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KIAEFMKN_03402 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)