ORF_ID e_value Gene_name EC_number CAZy COGs Description
OPKCENBM_00001 2.4e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OPKCENBM_00002 1.2e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OPKCENBM_00003 3.6e-286 L Transposase
OPKCENBM_00004 4.9e-207 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OPKCENBM_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OPKCENBM_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OPKCENBM_00007 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
OPKCENBM_00008 6.6e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OPKCENBM_00009 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OPKCENBM_00010 1.1e-156 corA P CorA-like Mg2+ transporter protein
OPKCENBM_00011 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OPKCENBM_00012 4.8e-76 rplI J Binds to the 23S rRNA
OPKCENBM_00013 1.4e-243 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OPKCENBM_00014 5e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
OPKCENBM_00015 3.8e-240 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_00016 1.4e-217 I Protein of unknown function (DUF2974)
OPKCENBM_00017 0.0
OPKCENBM_00018 1.2e-29
OPKCENBM_00020 6.5e-246 steT E amino acid
OPKCENBM_00022 1.9e-181 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_00023 1.2e-191 L Transposase IS66 family
OPKCENBM_00024 2.1e-35 GM domain, Protein
OPKCENBM_00025 1.3e-32 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPKCENBM_00026 2.9e-104 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPKCENBM_00027 1.2e-08 S Sterol carrier protein domain
OPKCENBM_00028 7.7e-130 S Sterol carrier protein domain
OPKCENBM_00029 1.6e-12 S Sterol carrier protein domain
OPKCENBM_00030 3.7e-130 arbZ I Acyltransferase
OPKCENBM_00031 8.5e-111 ywnB S NAD(P)H-binding
OPKCENBM_00032 2.5e-129 S Protein of unknown function (DUF975)
OPKCENBM_00033 9.2e-135 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
OPKCENBM_00034 6e-149 yitS S EDD domain protein, DegV family
OPKCENBM_00035 4.9e-19
OPKCENBM_00036 2.8e-288 V ABC-type multidrug transport system, ATPase and permease components
OPKCENBM_00037 3.7e-140 ropB K Helix-turn-helix domain
OPKCENBM_00038 0.0 tetP J elongation factor G
OPKCENBM_00039 8e-163 clcA P chloride
OPKCENBM_00040 1.3e-61 clcA P chloride
OPKCENBM_00041 6.6e-165 P CorA-like Mg2+ transporter protein
OPKCENBM_00043 4.2e-40 S Transglycosylase associated protein
OPKCENBM_00044 9.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
OPKCENBM_00045 0.0 L Helicase C-terminal domain protein
OPKCENBM_00046 3.8e-138 S Alpha beta hydrolase
OPKCENBM_00048 1.5e-29
OPKCENBM_00050 7.2e-16
OPKCENBM_00051 3.1e-171 K AI-2E family transporter
OPKCENBM_00052 3.4e-247 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
OPKCENBM_00053 1.8e-66 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OPKCENBM_00054 3.7e-21 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OPKCENBM_00055 7.7e-37 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OPKCENBM_00056 1.3e-97 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
OPKCENBM_00057 2.2e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OPKCENBM_00058 0.0 S domain, Protein
OPKCENBM_00059 7.1e-259 E amino acid
OPKCENBM_00060 4.6e-55 K LysR substrate binding domain
OPKCENBM_00061 0.0 1.3.5.4 C FAD binding domain
OPKCENBM_00062 1.1e-240 brnQ U Component of the transport system for branched-chain amino acids
OPKCENBM_00063 2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OPKCENBM_00064 9.6e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
OPKCENBM_00065 5.8e-61 S Peptidase propeptide and YPEB domain
OPKCENBM_00066 1.1e-102 L PFAM Integrase catalytic region
OPKCENBM_00067 3e-31 L Helix-turn-helix domain
OPKCENBM_00068 3.2e-183 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
OPKCENBM_00069 6.3e-249 yhjX_2 P Major Facilitator Superfamily
OPKCENBM_00070 2e-247 yhjX_2 P Major Facilitator Superfamily
OPKCENBM_00071 2.8e-162 arbZ I Phosphate acyltransferases
OPKCENBM_00072 4.2e-183 arbY M Glycosyl transferase family 8
OPKCENBM_00073 3.8e-184 arbY M Glycosyl transferase family 8
OPKCENBM_00074 8.8e-153 arbx M Glycosyl transferase family 8
OPKCENBM_00075 2e-146 arbV 2.3.1.51 I Acyl-transferase
OPKCENBM_00078 2.6e-129 K response regulator
OPKCENBM_00079 0.0 vicK 2.7.13.3 T Histidine kinase
OPKCENBM_00080 1.2e-241 yycH S YycH protein
OPKCENBM_00081 3.9e-145 yycI S YycH protein
OPKCENBM_00082 2.3e-142 vicX 3.1.26.11 S domain protein
OPKCENBM_00083 6.4e-176 htrA 3.4.21.107 O serine protease
OPKCENBM_00084 1.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OPKCENBM_00085 1.6e-109 P Cobalt transport protein
OPKCENBM_00086 1.3e-246 cbiO1 S ABC transporter, ATP-binding protein
OPKCENBM_00087 5.1e-96 S ABC-type cobalt transport system, permease component
OPKCENBM_00088 8.6e-165 K helix_turn_helix, arabinose operon control protein
OPKCENBM_00091 5.2e-28 S CAAX protease self-immunity
OPKCENBM_00092 5.5e-161 htpX O Belongs to the peptidase M48B family
OPKCENBM_00093 4.6e-89 lemA S LemA family
OPKCENBM_00094 7.3e-179 ybiR P Citrate transporter
OPKCENBM_00095 4.9e-64 S Iron-sulphur cluster biosynthesis
OPKCENBM_00096 1.7e-16
OPKCENBM_00097 6e-120
OPKCENBM_00099 9.7e-239 ydaM M Glycosyl transferase
OPKCENBM_00100 8.4e-199 G Glycosyl hydrolases family 8
OPKCENBM_00101 4.5e-120 yfbR S HD containing hydrolase-like enzyme
OPKCENBM_00102 5.4e-161 L HNH nucleases
OPKCENBM_00103 2e-45
OPKCENBM_00104 2.5e-138 glnQ E ABC transporter, ATP-binding protein
OPKCENBM_00105 1.4e-287 glnP P ABC transporter permease
OPKCENBM_00106 3.8e-114 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
OPKCENBM_00107 4.1e-62 yeaO S Protein of unknown function, DUF488
OPKCENBM_00108 4.1e-120 terC P Integral membrane protein TerC family
OPKCENBM_00109 1e-82 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
OPKCENBM_00110 2.2e-128 cobB K SIR2 family
OPKCENBM_00111 3.7e-79
OPKCENBM_00112 2.1e-157 L COG2963 Transposase and inactivated derivatives
OPKCENBM_00113 2.2e-32 L transposase activity
OPKCENBM_00114 1.9e-236 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OPKCENBM_00115 4.9e-82 yugP S Putative neutral zinc metallopeptidase
OPKCENBM_00116 5.5e-172 S Alpha/beta hydrolase of unknown function (DUF915)
OPKCENBM_00117 3.3e-135 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OPKCENBM_00119 1.5e-156 ypuA S Protein of unknown function (DUF1002)
OPKCENBM_00120 5e-140 epsV 2.7.8.12 S glycosyl transferase family 2
OPKCENBM_00121 2.6e-123 S Alpha/beta hydrolase family
OPKCENBM_00122 1e-60
OPKCENBM_00123 4.5e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OPKCENBM_00124 2.8e-241 cycA E Amino acid permease
OPKCENBM_00125 1.6e-112 luxT K Bacterial regulatory proteins, tetR family
OPKCENBM_00126 7.6e-120
OPKCENBM_00127 3.2e-265 S Cysteine-rich secretory protein family
OPKCENBM_00128 4.8e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OPKCENBM_00129 7.8e-81
OPKCENBM_00130 1.2e-272 yjcE P Sodium proton antiporter
OPKCENBM_00131 8.9e-169 yibE S overlaps another CDS with the same product name
OPKCENBM_00132 1.4e-117 yibF S overlaps another CDS with the same product name
OPKCENBM_00133 3.8e-151 I alpha/beta hydrolase fold
OPKCENBM_00134 0.0 G Belongs to the glycosyl hydrolase 31 family
OPKCENBM_00135 3.2e-127 XK27_08435 K UTRA
OPKCENBM_00136 1.3e-213 agaS G SIS domain
OPKCENBM_00137 1.7e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OPKCENBM_00138 6.9e-25 2.7.1.191 G PTS system sorbose subfamily IIB component
OPKCENBM_00139 1.2e-49 2.7.1.191 G PTS system sorbose subfamily IIB component
OPKCENBM_00140 5.9e-126 XK27_08455 G PTS system sorbose-specific iic component
OPKCENBM_00141 1.9e-56 manZ_1 G PTS system mannose/fructose/sorbose family IID component
OPKCENBM_00142 6.9e-69 manZ_1 G PTS system mannose/fructose/sorbose family IID component
OPKCENBM_00143 7.4e-65 2.7.1.191 G PTS system fructose IIA component
OPKCENBM_00144 9.2e-164 S zinc-ribbon domain
OPKCENBM_00145 5e-39 S MORN repeat protein
OPKCENBM_00146 3.4e-274 XK27_09800 I Acyltransferase family
OPKCENBM_00147 1.8e-86 ntd 2.4.2.6 F Nucleoside
OPKCENBM_00148 1e-99 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
OPKCENBM_00149 1.6e-129 XK27_08440 K UTRA domain
OPKCENBM_00150 1.3e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
OPKCENBM_00151 1e-87 uspA T universal stress protein
OPKCENBM_00153 9.8e-169 phnD P Phosphonate ABC transporter
OPKCENBM_00154 1.9e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OPKCENBM_00155 5.4e-131 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
OPKCENBM_00156 2.1e-146 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
OPKCENBM_00157 7.3e-83
OPKCENBM_00158 1.1e-272 S Calcineurin-like phosphoesterase
OPKCENBM_00159 0.0 asnB 6.3.5.4 E Asparagine synthase
OPKCENBM_00160 3.6e-265 yxbA 6.3.1.12 S ATP-grasp enzyme
OPKCENBM_00161 3.4e-64 K Helix-turn-helix XRE-family like proteins
OPKCENBM_00162 1.9e-19
OPKCENBM_00163 1.2e-54 V abc transporter atp-binding protein
OPKCENBM_00164 3.9e-43
OPKCENBM_00167 3.1e-34 CO COG0526, thiol-disulfide isomerase and thioredoxins
OPKCENBM_00168 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
OPKCENBM_00169 3.1e-130 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OPKCENBM_00170 4.1e-104 S Iron-sulfur cluster assembly protein
OPKCENBM_00171 9.2e-220 XK27_04775 S PAS domain
OPKCENBM_00172 1.4e-223 yttB EGP Major facilitator Superfamily
OPKCENBM_00173 8.3e-182 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
OPKCENBM_00174 3.9e-171 D nuclear chromosome segregation
OPKCENBM_00176 1.9e-208 yniG EGP Major facilitator Superfamily
OPKCENBM_00177 0.0 pepO 3.4.24.71 O Peptidase family M13
OPKCENBM_00178 6.4e-307 S Bacterial membrane protein, YfhO
OPKCENBM_00179 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
OPKCENBM_00180 0.0 kup P Transport of potassium into the cell
OPKCENBM_00181 0.0 kup P Transport of potassium into the cell
OPKCENBM_00182 1e-72
OPKCENBM_00183 2.8e-111
OPKCENBM_00184 1.1e-22
OPKCENBM_00185 7.9e-30 S Protein of unknown function (DUF2922)
OPKCENBM_00186 2.4e-214 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OPKCENBM_00187 2.9e-216 lysA2 M Glycosyl hydrolases family 25
OPKCENBM_00188 6.8e-142 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
OPKCENBM_00189 0.0 yjbQ P TrkA C-terminal domain protein
OPKCENBM_00190 1.8e-173 S Oxidoreductase family, NAD-binding Rossmann fold
OPKCENBM_00191 6.2e-132
OPKCENBM_00192 5.2e-145
OPKCENBM_00193 1.8e-72 S PAS domain
OPKCENBM_00194 9.3e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OPKCENBM_00195 5.2e-24 S HicB_like antitoxin of bacterial toxin-antitoxin system
OPKCENBM_00197 1.7e-39
OPKCENBM_00199 5e-09
OPKCENBM_00200 3.2e-12
OPKCENBM_00201 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OPKCENBM_00202 3.4e-71 2.4.1.83 GT2 S GtrA-like protein
OPKCENBM_00203 2e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
OPKCENBM_00204 4.5e-165 lmrB EGP Major facilitator Superfamily
OPKCENBM_00205 3e-117
OPKCENBM_00206 6.6e-151 glcU U sugar transport
OPKCENBM_00207 3.9e-167 yqhA G Aldose 1-epimerase
OPKCENBM_00208 2.4e-190 brpA K Cell envelope-like function transcriptional attenuator common domain protein
OPKCENBM_00209 3.7e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OPKCENBM_00210 0.0 XK27_08315 M Sulfatase
OPKCENBM_00211 2.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OPKCENBM_00213 2.4e-253 pepC 3.4.22.40 E aminopeptidase
OPKCENBM_00214 9.8e-115 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
OPKCENBM_00215 9.5e-153 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_00216 1.1e-30 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_00217 8.5e-251 pepC 3.4.22.40 E aminopeptidase
OPKCENBM_00218 1.7e-31
OPKCENBM_00219 5.4e-75 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OPKCENBM_00220 2.7e-73 hsp O Belongs to the small heat shock protein (HSP20) family
OPKCENBM_00221 1.6e-290 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OPKCENBM_00222 6e-80
OPKCENBM_00223 1.4e-243 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPKCENBM_00224 3e-122 yydK K UTRA
OPKCENBM_00225 6.2e-67 S Domain of unknown function (DUF3284)
OPKCENBM_00226 1.3e-300 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OPKCENBM_00227 5.7e-132 gmuR K UTRA
OPKCENBM_00228 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
OPKCENBM_00229 8.8e-40
OPKCENBM_00230 2.6e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
OPKCENBM_00231 7e-267 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPKCENBM_00232 1.5e-277 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OPKCENBM_00233 7.5e-155 ypbG 2.7.1.2 GK ROK family
OPKCENBM_00234 2.4e-113
OPKCENBM_00236 7.5e-85 E Belongs to the SOS response-associated peptidase family
OPKCENBM_00237 5.7e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
OPKCENBM_00238 9.6e-91 comEB 3.5.4.12 F MafB19-like deaminase
OPKCENBM_00239 8.3e-97 S TPM domain
OPKCENBM_00240 1.6e-180 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
OPKCENBM_00241 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OPKCENBM_00242 2.2e-145 tatD L hydrolase, TatD family
OPKCENBM_00243 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OPKCENBM_00244 1.2e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OPKCENBM_00245 2.2e-35 veg S Biofilm formation stimulator VEG
OPKCENBM_00246 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OPKCENBM_00247 1.4e-216 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OPKCENBM_00248 2.6e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OPKCENBM_00249 3e-173 yvdE K helix_turn _helix lactose operon repressor
OPKCENBM_00250 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
OPKCENBM_00251 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
OPKCENBM_00252 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
OPKCENBM_00253 7.6e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
OPKCENBM_00254 3.7e-207 msmX P Belongs to the ABC transporter superfamily
OPKCENBM_00255 2.8e-216 malE G Bacterial extracellular solute-binding protein
OPKCENBM_00256 3.6e-252 malF P Binding-protein-dependent transport system inner membrane component
OPKCENBM_00257 1.6e-152 malG P ABC transporter permease
OPKCENBM_00258 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
OPKCENBM_00259 4.4e-266 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
OPKCENBM_00260 1.9e-74 S Domain of unknown function (DUF1934)
OPKCENBM_00261 2.5e-63 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OPKCENBM_00262 5.8e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OPKCENBM_00263 9.4e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OPKCENBM_00264 1.5e-231 pbuX F xanthine permease
OPKCENBM_00265 2e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OPKCENBM_00266 4.1e-120 K Psort location CytoplasmicMembrane, score
OPKCENBM_00267 6.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OPKCENBM_00268 4.3e-241 V N-6 DNA Methylase
OPKCENBM_00270 1.1e-150 L COG2963 Transposase and inactivated derivatives
OPKCENBM_00271 3.9e-34 L PFAM Integrase catalytic region
OPKCENBM_00272 1.6e-31 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
OPKCENBM_00273 9.4e-12
OPKCENBM_00274 1.2e-106 K transcriptional regulator
OPKCENBM_00275 1.3e-93 yxkA S Phosphatidylethanolamine-binding protein
OPKCENBM_00276 9.4e-162 K Helix-turn-helix
OPKCENBM_00277 2.3e-176 Z012_01130 S Fic/DOC family
OPKCENBM_00278 3.9e-107 1.6.5.2 S NADPH-dependent FMN reductase
OPKCENBM_00279 4.7e-91 K Bacterial regulatory proteins, tetR family
OPKCENBM_00280 2.9e-17
OPKCENBM_00281 2.5e-214 ywhK S Membrane
OPKCENBM_00282 8.8e-34 XK27_09675 K Acetyltransferase (GNAT) domain
OPKCENBM_00283 3.1e-102 L PFAM Integrase catalytic region
OPKCENBM_00285 8.8e-08 Z012_00440 L Helix-turn-helix domain
OPKCENBM_00286 8.9e-95
OPKCENBM_00287 2.8e-265 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
OPKCENBM_00288 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
OPKCENBM_00289 7e-188 yfdV S Membrane transport protein
OPKCENBM_00290 5.6e-37
OPKCENBM_00291 3.9e-56 S Putative adhesin
OPKCENBM_00292 1.5e-74
OPKCENBM_00293 1.9e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
OPKCENBM_00294 2.6e-282 pipD E Dipeptidase
OPKCENBM_00295 1.4e-153 msmR K AraC-like ligand binding domain
OPKCENBM_00296 0.0 gph G Transporter
OPKCENBM_00297 0.0 rafA 3.2.1.22 G alpha-galactosidase
OPKCENBM_00298 3e-281 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
OPKCENBM_00299 4.6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OPKCENBM_00300 6.1e-177 ABC-SBP S ABC transporter
OPKCENBM_00301 5.1e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
OPKCENBM_00302 7.1e-133 XK27_08845 S ABC transporter, ATP-binding protein
OPKCENBM_00303 2.9e-293 ybeC E amino acid
OPKCENBM_00304 1.4e-40 rpmE2 J Ribosomal protein L31
OPKCENBM_00305 4e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OPKCENBM_00306 1.1e-267 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OPKCENBM_00307 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OPKCENBM_00308 2.2e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OPKCENBM_00309 1.6e-123 S (CBS) domain
OPKCENBM_00310 3.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OPKCENBM_00311 8.7e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OPKCENBM_00312 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OPKCENBM_00313 5.4e-34 yabO J S4 domain protein
OPKCENBM_00314 4e-60 divIC D Septum formation initiator
OPKCENBM_00315 1.2e-58 yabR J S1 RNA binding domain
OPKCENBM_00316 1e-243 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OPKCENBM_00317 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OPKCENBM_00318 0.0 S membrane
OPKCENBM_00319 0.0 S membrane
OPKCENBM_00320 6e-160 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OPKCENBM_00321 5.8e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OPKCENBM_00322 2.1e-301 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OPKCENBM_00323 1.6e-08
OPKCENBM_00325 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
OPKCENBM_00326 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OPKCENBM_00327 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OPKCENBM_00328 2.2e-93 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
OPKCENBM_00329 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OPKCENBM_00330 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OPKCENBM_00331 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OPKCENBM_00332 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
OPKCENBM_00333 1.7e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OPKCENBM_00334 1e-105 rplD J Forms part of the polypeptide exit tunnel
OPKCENBM_00335 1.7e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OPKCENBM_00336 1.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OPKCENBM_00337 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OPKCENBM_00338 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OPKCENBM_00339 1.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OPKCENBM_00340 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OPKCENBM_00341 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
OPKCENBM_00342 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OPKCENBM_00343 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OPKCENBM_00344 1.1e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OPKCENBM_00345 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OPKCENBM_00346 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OPKCENBM_00347 2.1e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OPKCENBM_00348 2.9e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OPKCENBM_00349 1.5e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OPKCENBM_00350 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OPKCENBM_00351 1.4e-23 rpmD J Ribosomal protein L30
OPKCENBM_00352 1.3e-70 rplO J Binds to the 23S rRNA
OPKCENBM_00353 4.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OPKCENBM_00354 4.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OPKCENBM_00355 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OPKCENBM_00356 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
OPKCENBM_00357 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OPKCENBM_00358 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OPKCENBM_00359 9.6e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OPKCENBM_00360 7.4e-62 rplQ J Ribosomal protein L17
OPKCENBM_00361 4.2e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OPKCENBM_00362 8.6e-159 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OPKCENBM_00363 2.1e-205 L Putative transposase DNA-binding domain
OPKCENBM_00364 1.1e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OPKCENBM_00365 4.3e-149 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OPKCENBM_00366 5e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OPKCENBM_00367 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
OPKCENBM_00368 0.0 LV site-specific DNA-methyltransferase (adenine-specific) activity
OPKCENBM_00369 1.6e-108 cobB K Sir2 family
OPKCENBM_00370 1e-116 GM NAD(P)H-binding
OPKCENBM_00371 2.3e-196 S membrane
OPKCENBM_00372 4.4e-98 K Transcriptional regulator C-terminal region
OPKCENBM_00373 1.5e-150 1.6.5.2 GM NmrA-like family
OPKCENBM_00374 1.9e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
OPKCENBM_00375 1.3e-128 pgm3 G Belongs to the phosphoglycerate mutase family
OPKCENBM_00376 4.2e-50 K Transcriptional regulator, ArsR family
OPKCENBM_00377 1.1e-153 czcD P cation diffusion facilitator family transporter
OPKCENBM_00378 9.1e-32
OPKCENBM_00379 1.3e-11
OPKCENBM_00380 3.1e-124 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OPKCENBM_00381 4.4e-185 S AAA domain
OPKCENBM_00382 3.9e-34 L PFAM Integrase catalytic region
OPKCENBM_00383 4.4e-115 L COG2963 Transposase and inactivated derivatives
OPKCENBM_00384 9.1e-34 L transposase activity
OPKCENBM_00385 2.9e-296 gadC E Contains amino acid permease domain
OPKCENBM_00386 9.1e-34 L transposase activity
OPKCENBM_00387 4.4e-115 L COG2963 Transposase and inactivated derivatives
OPKCENBM_00388 3.9e-34 L PFAM Integrase catalytic region
OPKCENBM_00389 1.3e-210 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
OPKCENBM_00390 1.4e-281 asp1 S Accessory Sec system protein Asp1
OPKCENBM_00391 2e-299 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
OPKCENBM_00392 1.9e-150 asp3 S Accessory Sec secretory system ASP3
OPKCENBM_00393 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OPKCENBM_00394 2e-288 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
OPKCENBM_00395 2.1e-249 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
OPKCENBM_00397 5.7e-16 UW Tetratricopeptide repeat
OPKCENBM_00399 9.4e-20 UW Tetratricopeptide repeat
OPKCENBM_00400 7.6e-163 cpsJ S glycosyl transferase family 2
OPKCENBM_00401 2.6e-41 L Helix-turn-helix domain
OPKCENBM_00402 7.7e-101 L PFAM Integrase catalytic region
OPKCENBM_00403 4.9e-190 nss M transferase activity, transferring glycosyl groups
OPKCENBM_00404 2.8e-265 pepC 3.4.22.40 E Peptidase C1-like family
OPKCENBM_00405 5.3e-190 brpA K Cell envelope-like function transcriptional attenuator common domain protein
OPKCENBM_00406 7.7e-101 L PFAM Integrase catalytic region
OPKCENBM_00407 2.6e-41 L Helix-turn-helix domain
OPKCENBM_00408 3.6e-102 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
OPKCENBM_00409 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OPKCENBM_00410 3.8e-287 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OPKCENBM_00411 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OPKCENBM_00412 1.3e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OPKCENBM_00413 1e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OPKCENBM_00414 4.6e-89 yvrI K sigma factor activity
OPKCENBM_00415 1.7e-34
OPKCENBM_00416 2.4e-165 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
OPKCENBM_00417 8.2e-67 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
OPKCENBM_00418 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OPKCENBM_00419 1.3e-227 G Major Facilitator Superfamily
OPKCENBM_00420 8.2e-188 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OPKCENBM_00421 3.4e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OPKCENBM_00422 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
OPKCENBM_00423 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OPKCENBM_00424 3.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OPKCENBM_00425 4.2e-209 L Putative transposase DNA-binding domain
OPKCENBM_00426 7.9e-109 glnP P ABC transporter permease
OPKCENBM_00427 4.4e-115 glnQ 3.6.3.21 E ABC transporter
OPKCENBM_00428 2.9e-145 aatB ET ABC transporter substrate-binding protein
OPKCENBM_00429 5.8e-95 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OPKCENBM_00430 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OPKCENBM_00431 8e-128 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
OPKCENBM_00432 2.7e-32
OPKCENBM_00433 2.8e-111 rsmC 2.1.1.172 J Methyltransferase
OPKCENBM_00434 3.9e-21
OPKCENBM_00435 1.3e-143
OPKCENBM_00436 5.2e-40 S Protein conserved in bacteria
OPKCENBM_00437 1e-84 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OPKCENBM_00438 9.7e-306 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OPKCENBM_00439 5.9e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OPKCENBM_00440 6.9e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OPKCENBM_00441 9e-26 S Protein of unknown function (DUF2508)
OPKCENBM_00442 1.2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OPKCENBM_00443 8.5e-11 yaaQ S Cyclic-di-AMP receptor
OPKCENBM_00444 3.5e-152 holB 2.7.7.7 L DNA polymerase III
OPKCENBM_00445 4.4e-58 yabA L Involved in initiation control of chromosome replication
OPKCENBM_00446 7.4e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OPKCENBM_00447 1.1e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
OPKCENBM_00448 1.5e-78 folT S ECF transporter, substrate-specific component
OPKCENBM_00449 7.8e-129 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
OPKCENBM_00450 6.4e-96 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
OPKCENBM_00451 9.9e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OPKCENBM_00452 3.8e-108
OPKCENBM_00453 6.8e-14
OPKCENBM_00454 1.2e-161 S AAA domain, putative AbiEii toxin, Type IV TA system
OPKCENBM_00455 1.2e-220 clcA P chloride
OPKCENBM_00456 1.7e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OPKCENBM_00457 2.5e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OPKCENBM_00458 1.4e-242 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OPKCENBM_00459 1.1e-122 L oxidized base lesion DNA N-glycosylase activity
OPKCENBM_00460 3e-70 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
OPKCENBM_00461 1.1e-47 L bacterial-type proximal promoter sequence-specific DNA binding
OPKCENBM_00462 5.6e-52 S Bacterial toxin of type II toxin-antitoxin system, YafQ
OPKCENBM_00463 6.2e-221 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
OPKCENBM_00464 5.6e-67 K Helix-turn-helix XRE-family like proteins
OPKCENBM_00465 2.4e-146 G Transmembrane secretion effector
OPKCENBM_00466 3.9e-145 K Helix-turn-helix XRE-family like proteins
OPKCENBM_00469 1.9e-75
OPKCENBM_00470 1.9e-242 G Bacterial extracellular solute-binding protein
OPKCENBM_00471 1.6e-298 uup S ABC transporter, ATP-binding protein
OPKCENBM_00472 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OPKCENBM_00473 3.7e-102 yvdD 3.2.2.10 S Belongs to the LOG family
OPKCENBM_00474 4.8e-91 K UTRA domain
OPKCENBM_00475 2.4e-116 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPKCENBM_00476 3.3e-47 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPKCENBM_00477 2.8e-13 3.1.1.53 G Belongs to the glycosyl hydrolase 2 family
OPKCENBM_00478 2.2e-68 3.1.1.53 E Pfam:DUF303
OPKCENBM_00479 6.5e-32 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
OPKCENBM_00480 6.1e-79 XK27_02470 K LytTr DNA-binding domain
OPKCENBM_00481 7.6e-119 liaI S membrane
OPKCENBM_00482 1.1e-102 L PFAM Integrase catalytic region
OPKCENBM_00483 2.6e-41 L Helix-turn-helix domain
OPKCENBM_00485 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OPKCENBM_00486 3.5e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OPKCENBM_00487 1.7e-108
OPKCENBM_00488 0.0 nisT V ABC transporter
OPKCENBM_00489 1.1e-59
OPKCENBM_00491 1.2e-09 V (ABC) transporter
OPKCENBM_00492 8.3e-23 spaB S Lantibiotic dehydratase, C terminus
OPKCENBM_00493 2.1e-17 spaC2 V Lanthionine synthetase C family protein
OPKCENBM_00494 1.7e-68 V ABC transporter
OPKCENBM_00495 8.6e-92 V ABC transporter
OPKCENBM_00496 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OPKCENBM_00497 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OPKCENBM_00498 9.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OPKCENBM_00499 4.3e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OPKCENBM_00500 1.2e-39 yajC U Preprotein translocase
OPKCENBM_00501 1.7e-281 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OPKCENBM_00502 4.2e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OPKCENBM_00503 9.5e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
OPKCENBM_00504 4e-227 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OPKCENBM_00505 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OPKCENBM_00506 2.6e-42 yrzL S Belongs to the UPF0297 family
OPKCENBM_00507 8.8e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OPKCENBM_00508 4.2e-39 yrzB S Belongs to the UPF0473 family
OPKCENBM_00509 3.3e-92 cvpA S Colicin V production protein
OPKCENBM_00510 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OPKCENBM_00511 1.1e-52 trxA O Belongs to the thioredoxin family
OPKCENBM_00512 5.5e-192 L COG2963 Transposase and inactivated derivatives
OPKCENBM_00513 2.7e-67 yslB S Protein of unknown function (DUF2507)
OPKCENBM_00514 1.2e-141 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OPKCENBM_00515 5.9e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OPKCENBM_00516 3.3e-214 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OPKCENBM_00517 5.1e-138 ykuT M mechanosensitive ion channel
OPKCENBM_00518 1.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OPKCENBM_00519 8.1e-49
OPKCENBM_00520 6.1e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
OPKCENBM_00521 3e-171 ccpA K catabolite control protein A
OPKCENBM_00522 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
OPKCENBM_00523 2.6e-274 pepV 3.5.1.18 E dipeptidase PepV
OPKCENBM_00524 1.2e-266 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OPKCENBM_00525 3.3e-55
OPKCENBM_00526 1e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OPKCENBM_00527 2.6e-97 yutD S Protein of unknown function (DUF1027)
OPKCENBM_00528 6.2e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OPKCENBM_00529 1.5e-104 S Protein of unknown function (DUF1461)
OPKCENBM_00530 8e-117 dedA S SNARE-like domain protein
OPKCENBM_00531 4.4e-172 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
OPKCENBM_00532 7.9e-61 yugI 5.3.1.9 J general stress protein
OPKCENBM_00533 2.1e-22 S ORF located using Blastx
OPKCENBM_00534 3.3e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
OPKCENBM_00539 2.4e-215 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OPKCENBM_00540 2.1e-250 qacA EGP Major facilitator Superfamily
OPKCENBM_00541 3.1e-102 L PFAM Integrase catalytic region
OPKCENBM_00543 2.1e-24 L Helix-turn-helix domain
OPKCENBM_00544 8.3e-114 3.6.1.27 I Acid phosphatase homologues
OPKCENBM_00545 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OPKCENBM_00546 8.9e-298 ytgP S Polysaccharide biosynthesis protein
OPKCENBM_00547 4.1e-217 MA20_36090 S Protein of unknown function (DUF2974)
OPKCENBM_00548 1e-136
OPKCENBM_00549 3.2e-142 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OPKCENBM_00550 1.6e-163 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OPKCENBM_00551 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OPKCENBM_00552 1.9e-172 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
OPKCENBM_00553 1.8e-45
OPKCENBM_00555 1e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OPKCENBM_00556 1.5e-123 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
OPKCENBM_00557 7.8e-109 ylbE GM NAD(P)H-binding
OPKCENBM_00558 1e-78 yebR 1.8.4.14 T GAF domain-containing protein
OPKCENBM_00559 4.7e-33 yfeO P Voltage gated chloride channel
OPKCENBM_00560 3.5e-188 S Bacteriocin helveticin-J
OPKCENBM_00561 2.3e-96 tag 3.2.2.20 L glycosylase
OPKCENBM_00562 3.4e-161 mleP3 S Membrane transport protein
OPKCENBM_00563 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
OPKCENBM_00564 7.8e-253 emrY EGP Major facilitator Superfamily
OPKCENBM_00565 9.4e-259 emrY EGP Major facilitator Superfamily
OPKCENBM_00566 1e-75 2.3.1.128 K acetyltransferase
OPKCENBM_00567 9.1e-274 L Transposase
OPKCENBM_00568 8.4e-59 S PFAM Archaeal ATPase
OPKCENBM_00569 8.4e-121 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OPKCENBM_00570 1.4e-66 K Transcriptional regulator
OPKCENBM_00571 1.5e-239 pyrP F Permease
OPKCENBM_00572 4.2e-77 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
OPKCENBM_00573 5.1e-201 S PFAM Archaeal ATPase
OPKCENBM_00574 2.1e-89 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
OPKCENBM_00575 9.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
OPKCENBM_00576 2.8e-111 3.6.1.27 I Acid phosphatase homologues
OPKCENBM_00577 7.9e-284 E Phospholipase B
OPKCENBM_00578 1.6e-176 pepC 3.4.22.40 E Peptidase C1-like family
OPKCENBM_00579 1.3e-40 pepC 3.4.22.40 E Peptidase C1-like family
OPKCENBM_00580 2.2e-08 pepC 3.4.22.40 E Peptidase C1-like family
OPKCENBM_00581 5.9e-248 gadC E Contains amino acid permease domain
OPKCENBM_00582 2.3e-22 gadC E Contains amino acid permease domain
OPKCENBM_00583 8.6e-273 pipD E Peptidase family C69
OPKCENBM_00584 4.4e-263 pepC 3.4.22.40 E Peptidase C1-like family
OPKCENBM_00585 5.2e-306 gadC E Contains amino acid permease domain
OPKCENBM_00586 4.3e-237 yagE E amino acid
OPKCENBM_00587 1.7e-293 E Amino acid permease
OPKCENBM_00588 4.2e-212 mdtG EGP Major facilitator Superfamily
OPKCENBM_00589 6.1e-26
OPKCENBM_00590 2.1e-59 K helix_turn_helix multiple antibiotic resistance protein
OPKCENBM_00591 1.4e-203 pepA E M42 glutamyl aminopeptidase
OPKCENBM_00593 7.8e-112 ybbL S ABC transporter, ATP-binding protein
OPKCENBM_00594 1.6e-129 ybbM S Uncharacterised protein family (UPF0014)
OPKCENBM_00595 3.6e-254 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
OPKCENBM_00596 1.3e-260 aaxC E Arginine ornithine antiporter
OPKCENBM_00597 3e-248 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
OPKCENBM_00598 4e-26 lacA 3.2.1.23 G -beta-galactosidase
OPKCENBM_00599 3.3e-283 dtpT U amino acid peptide transporter
OPKCENBM_00600 6.4e-182 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_00601 6e-279 pipD E Peptidase family C69
OPKCENBM_00602 1.2e-217 naiP EGP Major facilitator Superfamily
OPKCENBM_00603 7.4e-155 S Alpha beta hydrolase
OPKCENBM_00604 8.7e-67 K Transcriptional regulator, MarR family
OPKCENBM_00605 1.7e-299 XK27_09600 V ABC transporter, ATP-binding protein
OPKCENBM_00606 0.0 V ABC transporter transmembrane region
OPKCENBM_00607 1.2e-146 glnH ET ABC transporter
OPKCENBM_00608 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
OPKCENBM_00609 3.1e-150 glnH ET ABC transporter
OPKCENBM_00610 2.4e-110 gluC P ABC transporter permease
OPKCENBM_00611 5.7e-107 glnP P ABC transporter permease
OPKCENBM_00612 1.9e-65
OPKCENBM_00613 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
OPKCENBM_00614 3.1e-130 treR K UTRA
OPKCENBM_00615 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OPKCENBM_00616 1.4e-75 S Putative adhesin
OPKCENBM_00618 8.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
OPKCENBM_00620 9.9e-190 2.7.13.3 T GHKL domain
OPKCENBM_00621 5.6e-222 L Putative transposase DNA-binding domain
OPKCENBM_00622 1.8e-139 K LytTr DNA-binding domain
OPKCENBM_00623 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
OPKCENBM_00624 1.1e-96 M Transport protein ComB
OPKCENBM_00625 1e-23 S Enterocin A Immunity
OPKCENBM_00630 1.8e-53 S Enterocin A Immunity
OPKCENBM_00632 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
OPKCENBM_00633 8.6e-104 rssA S Phospholipase, patatin family
OPKCENBM_00634 3.4e-256 glnPH2 P ABC transporter permease
OPKCENBM_00635 5.1e-128 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
OPKCENBM_00636 8.1e-96 K Acetyltransferase (GNAT) domain
OPKCENBM_00637 1.7e-159 pstS P Phosphate
OPKCENBM_00638 1.2e-161 pstC P probably responsible for the translocation of the substrate across the membrane
OPKCENBM_00639 2.4e-156 pstA P Phosphate transport system permease protein PstA
OPKCENBM_00640 1.6e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OPKCENBM_00641 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OPKCENBM_00642 4.2e-108 phoU P Plays a role in the regulation of phosphate uptake
OPKCENBM_00643 2.7e-280 S C4-dicarboxylate anaerobic carrier
OPKCENBM_00644 2.6e-85 dps P Belongs to the Dps family
OPKCENBM_00645 1.3e-157 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OPKCENBM_00646 3.5e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OPKCENBM_00647 2e-169 rihB 3.2.2.1 F Nucleoside
OPKCENBM_00648 3.4e-132 gntR K UbiC transcription regulator-associated domain protein
OPKCENBM_00649 2.2e-51 S Enterocin A Immunity
OPKCENBM_00650 2e-138 glcR K DeoR C terminal sensor domain
OPKCENBM_00651 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
OPKCENBM_00652 3.2e-113 C nitroreductase
OPKCENBM_00653 4.5e-126
OPKCENBM_00654 2.5e-237 yhdP S Transporter associated domain
OPKCENBM_00655 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OPKCENBM_00656 5e-227 potE E amino acid
OPKCENBM_00657 3.5e-134 M Glycosyl hydrolases family 25
OPKCENBM_00658 3.1e-202 yfmL 3.6.4.13 L DEAD DEAH box helicase
OPKCENBM_00659 5.2e-248 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPKCENBM_00662 4.7e-213 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OPKCENBM_00663 1.5e-101 L PFAM Integrase catalytic region
OPKCENBM_00664 2.6e-41 L Helix-turn-helix domain
OPKCENBM_00665 3.3e-86 gtcA S Teichoic acid glycosylation protein
OPKCENBM_00666 2.5e-77 fld C Flavodoxin
OPKCENBM_00667 1.9e-160 map 3.4.11.18 E Methionine Aminopeptidase
OPKCENBM_00668 1.3e-162 yihY S Belongs to the UPF0761 family
OPKCENBM_00669 8.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OPKCENBM_00670 2e-180 E ABC transporter, ATP-binding protein
OPKCENBM_00671 1.3e-279 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OPKCENBM_00672 9.6e-68 O OsmC-like protein
OPKCENBM_00673 1.4e-116 ltrA S Bacterial low temperature requirement A protein (LtrA)
OPKCENBM_00674 2.3e-113 2.7.6.5 T Region found in RelA / SpoT proteins
OPKCENBM_00675 2.2e-114 K response regulator
OPKCENBM_00676 1.9e-223 sptS 2.7.13.3 T Histidine kinase
OPKCENBM_00677 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
OPKCENBM_00678 2.5e-52
OPKCENBM_00679 0.0 pepN 3.4.11.2 E aminopeptidase
OPKCENBM_00680 2.2e-142 S haloacid dehalogenase-like hydrolase
OPKCENBM_00682 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OPKCENBM_00683 2.2e-67
OPKCENBM_00684 4.7e-43 fic D Fic/DOC family
OPKCENBM_00685 1.1e-87 L Transposase
OPKCENBM_00686 2.3e-177 L Transposase
OPKCENBM_00687 1.9e-133 ppm1 GT2 M Glycosyl transferase family 2
OPKCENBM_00688 8.5e-83 S Domain of unknown function (DUF4811)
OPKCENBM_00689 6.4e-263 lmrB EGP Major facilitator Superfamily
OPKCENBM_00690 3.6e-73 K MerR HTH family regulatory protein
OPKCENBM_00691 5.1e-110 oppA E ABC transporter substrate-binding protein
OPKCENBM_00692 1.3e-51 oppA E ABC transporter substrate-binding protein
OPKCENBM_00693 1.6e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
OPKCENBM_00694 1.8e-256 pepC 3.4.22.40 E Peptidase C1-like family
OPKCENBM_00696 6.5e-19 K Transcriptional regulator, TetR family
OPKCENBM_00697 1e-47 K Transcriptional regulator, TetR family
OPKCENBM_00699 7.7e-78 3.4.22.70 M Sortase family
OPKCENBM_00700 5.9e-42 2.7.1.2 GK ROK family
OPKCENBM_00701 1.9e-101 2.7.1.2 GK ROK family
OPKCENBM_00702 4.3e-61 K AraC-like ligand binding domain
OPKCENBM_00703 1e-50 rhaS6 K helix_turn_helix, arabinose operon control protein
OPKCENBM_00704 9.8e-174 I Carboxylesterase family
OPKCENBM_00705 2.5e-311 S Predicted membrane protein (DUF2207)
OPKCENBM_00706 1.5e-123 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
OPKCENBM_00707 1.5e-55
OPKCENBM_00708 5.6e-147 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
OPKCENBM_00709 3.8e-91 S ECF-type riboflavin transporter, S component
OPKCENBM_00710 4.7e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
OPKCENBM_00711 4.1e-63
OPKCENBM_00712 3.5e-12
OPKCENBM_00713 5.8e-215 S Uncharacterized protein conserved in bacteria (DUF2325)
OPKCENBM_00714 3.2e-150 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OPKCENBM_00715 9.3e-59 arsC 1.20.4.1 P Belongs to the ArsC family
OPKCENBM_00716 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
OPKCENBM_00717 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OPKCENBM_00718 8.3e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
OPKCENBM_00719 1.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OPKCENBM_00720 3.1e-72 yqhY S Asp23 family, cell envelope-related function
OPKCENBM_00721 1.8e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OPKCENBM_00722 1.2e-152 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OPKCENBM_00723 7.2e-253 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OPKCENBM_00724 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OPKCENBM_00725 7.3e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OPKCENBM_00726 5.4e-155 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
OPKCENBM_00727 1e-293 recN L May be involved in recombinational repair of damaged DNA
OPKCENBM_00728 2.1e-24 L Helix-turn-helix domain
OPKCENBM_00730 1.1e-102 L PFAM Integrase catalytic region
OPKCENBM_00731 1.4e-47
OPKCENBM_00732 7.3e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
OPKCENBM_00733 2.3e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OPKCENBM_00734 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OPKCENBM_00735 4.3e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OPKCENBM_00736 3.7e-238 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OPKCENBM_00737 4.5e-140 stp 3.1.3.16 T phosphatase
OPKCENBM_00738 0.0 KLT serine threonine protein kinase
OPKCENBM_00739 5.4e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OPKCENBM_00740 4.1e-121 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OPKCENBM_00741 1.7e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
OPKCENBM_00742 1.2e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OPKCENBM_00743 1.4e-57 asp S Asp23 family, cell envelope-related function
OPKCENBM_00744 3.8e-304 yloV S DAK2 domain fusion protein YloV
OPKCENBM_00745 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OPKCENBM_00746 3.9e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OPKCENBM_00747 4.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OPKCENBM_00748 9e-192 oppD P Belongs to the ABC transporter superfamily
OPKCENBM_00749 1.1e-178 oppF P Belongs to the ABC transporter superfamily
OPKCENBM_00750 1.6e-177 oppB P ABC transporter permease
OPKCENBM_00751 4.3e-161 oppC P Binding-protein-dependent transport system inner membrane component
OPKCENBM_00752 0.0 oppA E ABC transporter substrate-binding protein
OPKCENBM_00753 0.0 oppA E ABC transporter substrate-binding protein
OPKCENBM_00754 2.1e-24 L Helix-turn-helix domain
OPKCENBM_00756 1.5e-101 L PFAM Integrase catalytic region
OPKCENBM_00757 1.6e-120 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OPKCENBM_00758 0.0 smc D Required for chromosome condensation and partitioning
OPKCENBM_00759 5.3e-165 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OPKCENBM_00760 8.8e-286 pipD E Dipeptidase
OPKCENBM_00761 1.9e-192 L COG2963 Transposase and inactivated derivatives
OPKCENBM_00762 4e-145 UW LPXTG-motif cell wall anchor domain protein
OPKCENBM_00763 1.2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OPKCENBM_00764 1.4e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OPKCENBM_00765 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OPKCENBM_00766 3.1e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OPKCENBM_00767 5.5e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OPKCENBM_00768 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OPKCENBM_00769 1e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
OPKCENBM_00770 8.6e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
OPKCENBM_00771 2.1e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
OPKCENBM_00772 3.9e-113 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OPKCENBM_00773 1.1e-34 ynzC S UPF0291 protein
OPKCENBM_00774 1.9e-30 yneF S Uncharacterised protein family (UPF0154)
OPKCENBM_00775 0.0 mdlA V ABC transporter
OPKCENBM_00776 3e-283 mdlB V ABC transporter
OPKCENBM_00777 2.6e-41 L Helix-turn-helix domain
OPKCENBM_00778 1.5e-101 L PFAM Integrase catalytic region
OPKCENBM_00779 3e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
OPKCENBM_00780 2.6e-117 plsC 2.3.1.51 I Acyltransferase
OPKCENBM_00781 3.9e-195 yabB 2.1.1.223 L Methyltransferase small domain
OPKCENBM_00782 5.8e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
OPKCENBM_00783 3.5e-183 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OPKCENBM_00784 1.8e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OPKCENBM_00785 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OPKCENBM_00786 8.5e-136 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OPKCENBM_00787 1.5e-138 cdsA 2.7.7.41 S Belongs to the CDS family
OPKCENBM_00788 7.1e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
OPKCENBM_00789 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OPKCENBM_00790 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OPKCENBM_00791 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
OPKCENBM_00792 9.4e-220 nusA K Participates in both transcription termination and antitermination
OPKCENBM_00793 1.5e-46 ylxR K Protein of unknown function (DUF448)
OPKCENBM_00794 7.1e-47 rplGA J ribosomal protein
OPKCENBM_00795 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OPKCENBM_00796 3.5e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OPKCENBM_00797 2.6e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OPKCENBM_00798 1.7e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OPKCENBM_00799 2.6e-272 lsa S ABC transporter
OPKCENBM_00800 2.7e-64 ropB K Transcriptional regulator
OPKCENBM_00802 1.4e-25 thiF 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
OPKCENBM_00803 6.6e-165 V ABC transporter transmembrane region
OPKCENBM_00804 5.5e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OPKCENBM_00805 9.4e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OPKCENBM_00806 0.0 dnaK O Heat shock 70 kDa protein
OPKCENBM_00807 5.7e-174 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OPKCENBM_00808 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OPKCENBM_00809 7.1e-124 srtA 3.4.22.70 M sortase family
OPKCENBM_00810 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OPKCENBM_00811 4.8e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OPKCENBM_00812 5.1e-276 yjeM E Amino Acid
OPKCENBM_00813 9.2e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OPKCENBM_00814 3.7e-187 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OPKCENBM_00815 3.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OPKCENBM_00816 1.7e-251 G Major Facilitator
OPKCENBM_00817 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
OPKCENBM_00818 2.8e-154 lysR5 K LysR substrate binding domain
OPKCENBM_00819 1.5e-101 L PFAM Integrase catalytic region
OPKCENBM_00821 2.1e-24 L Helix-turn-helix domain
OPKCENBM_00823 8.5e-102 3.6.1.27 I Acid phosphatase homologues
OPKCENBM_00824 6.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OPKCENBM_00825 3.7e-18 S Sugar efflux transporter for intercellular exchange
OPKCENBM_00826 1.1e-303 ybiT S ABC transporter, ATP-binding protein
OPKCENBM_00827 1.2e-15 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
OPKCENBM_00828 4.5e-157 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
OPKCENBM_00829 2.3e-48 K Helix-turn-helix domain
OPKCENBM_00830 1.5e-139 F DNA/RNA non-specific endonuclease
OPKCENBM_00831 1.4e-55 L nuclease
OPKCENBM_00832 1e-156 metQ1 P Belongs to the nlpA lipoprotein family
OPKCENBM_00833 1e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OPKCENBM_00834 1.8e-66 metI P ABC transporter permease
OPKCENBM_00835 2.9e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OPKCENBM_00836 2.1e-260 frdC 1.3.5.4 C FAD binding domain
OPKCENBM_00837 2.2e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OPKCENBM_00838 2.8e-244 yjjP S Putative threonine/serine exporter
OPKCENBM_00839 1.1e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
OPKCENBM_00840 0.0 aha1 P E1-E2 ATPase
OPKCENBM_00841 1.1e-308 S Bacterial membrane protein, YfhO
OPKCENBM_00842 9.1e-34 L transposase activity
OPKCENBM_00843 4.4e-115 L COG2963 Transposase and inactivated derivatives
OPKCENBM_00844 5e-34 L PFAM Integrase catalytic region
OPKCENBM_00845 7.7e-241 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_00846 1.4e-285 S Bacterial membrane protein, YfhO
OPKCENBM_00847 1.5e-67 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OPKCENBM_00848 1.9e-172 prmA J Ribosomal protein L11 methyltransferase
OPKCENBM_00849 2.4e-65
OPKCENBM_00850 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OPKCENBM_00851 1.3e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OPKCENBM_00852 6.2e-246 hisS 6.1.1.21 J histidyl-tRNA synthetase
OPKCENBM_00853 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
OPKCENBM_00854 2e-222 patA 2.6.1.1 E Aminotransferase
OPKCENBM_00855 1.7e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
OPKCENBM_00856 5.1e-139 E GDSL-like Lipase/Acylhydrolase family
OPKCENBM_00857 7.3e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OPKCENBM_00858 4.5e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OPKCENBM_00859 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
OPKCENBM_00860 6.1e-152 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
OPKCENBM_00861 4.4e-52 S Iron-sulfur cluster assembly protein
OPKCENBM_00862 6.6e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OPKCENBM_00863 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OPKCENBM_00864 2.9e-33 yqeY S YqeY-like protein
OPKCENBM_00865 9.5e-175 phoH T phosphate starvation-inducible protein PhoH
OPKCENBM_00866 1.2e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OPKCENBM_00867 4.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OPKCENBM_00868 4.9e-134 recO L Involved in DNA repair and RecF pathway recombination
OPKCENBM_00869 1e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
OPKCENBM_00870 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
OPKCENBM_00871 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OPKCENBM_00872 7.1e-198 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OPKCENBM_00873 5e-09 P ABC transporter permease
OPKCENBM_00874 3.2e-72 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
OPKCENBM_00875 2e-125 cjaA ET ABC transporter substrate-binding protein
OPKCENBM_00876 2.6e-121 trmK 2.1.1.217 S SAM-dependent methyltransferase
OPKCENBM_00877 1.6e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OPKCENBM_00878 9.2e-247 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OPKCENBM_00879 5.3e-57 yvoA_1 K Transcriptional regulator, GntR family
OPKCENBM_00880 1.8e-122 skfE V ATPases associated with a variety of cellular activities
OPKCENBM_00881 4.2e-139
OPKCENBM_00882 1.9e-111
OPKCENBM_00883 3.9e-34 L PFAM Integrase catalytic region
OPKCENBM_00884 1.5e-115 L COG2963 Transposase and inactivated derivatives
OPKCENBM_00885 9.1e-34 L transposase activity
OPKCENBM_00886 1.4e-21
OPKCENBM_00887 3.7e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
OPKCENBM_00888 7.3e-127
OPKCENBM_00889 2e-172
OPKCENBM_00890 6e-263 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
OPKCENBM_00891 2.1e-49 ybjQ S Belongs to the UPF0145 family
OPKCENBM_00892 9.6e-173 XK27_05540 S DUF218 domain
OPKCENBM_00893 1.1e-147 yxeH S hydrolase
OPKCENBM_00894 1.7e-301 I Protein of unknown function (DUF2974)
OPKCENBM_00895 2.7e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OPKCENBM_00896 1.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OPKCENBM_00897 1.3e-165 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OPKCENBM_00898 4.3e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OPKCENBM_00899 4.1e-178 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OPKCENBM_00900 1.7e-232 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OPKCENBM_00901 1.1e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OPKCENBM_00902 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
OPKCENBM_00903 1.2e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OPKCENBM_00904 1.6e-105 pncA Q Isochorismatase family
OPKCENBM_00905 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OPKCENBM_00906 3.6e-143 M Glycosyl transferases group 1
OPKCENBM_00907 2.7e-47 M Glycosyl transferases group 1
OPKCENBM_00908 4.8e-109 alkD L DNA alkylation repair enzyme
OPKCENBM_00909 5.2e-114 XK27_06785 V ABC transporter, ATP-binding protein
OPKCENBM_00910 0.0 XK27_06780 V ABC transporter permease
OPKCENBM_00911 0.0 pepO 3.4.24.71 O Peptidase family M13
OPKCENBM_00912 1.3e-114 drgA C nitroreductase
OPKCENBM_00913 2e-70 S SnoaL-like domain
OPKCENBM_00914 4e-75 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
OPKCENBM_00915 9.7e-203 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OPKCENBM_00916 5.7e-10 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
OPKCENBM_00917 3.9e-135 qmcA O prohibitin homologues
OPKCENBM_00918 1.6e-182 P ABC transporter
OPKCENBM_00919 1.2e-291 V ABC-type multidrug transport system, ATPase and permease components
OPKCENBM_00920 1.4e-11 S Putative adhesin
OPKCENBM_00921 5.6e-63
OPKCENBM_00922 1.9e-79 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
OPKCENBM_00923 1.7e-202 yhjX P Major Facilitator Superfamily
OPKCENBM_00924 1.1e-78 C nitroreductase
OPKCENBM_00925 1.2e-45
OPKCENBM_00926 2.2e-73 K Acetyltransferase (GNAT) domain
OPKCENBM_00927 1.3e-72
OPKCENBM_00928 5e-81 FG HIT domain
OPKCENBM_00929 8.2e-87 S Protein of unknown function (DUF2785)
OPKCENBM_00930 5.2e-47 S MazG-like family
OPKCENBM_00931 7.2e-59
OPKCENBM_00932 2.8e-116 3.1.3.48 T Tyrosine phosphatase family
OPKCENBM_00933 1.1e-38
OPKCENBM_00934 4.9e-251 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OPKCENBM_00935 1.2e-137 aroD S Serine hydrolase (FSH1)
OPKCENBM_00936 4.8e-88 rimL J Acetyltransferase (GNAT) domain
OPKCENBM_00937 4.1e-89 2.3.1.57 K Acetyltransferase (GNAT) family
OPKCENBM_00938 2e-109 XK27_07525 3.6.1.55 F NUDIX domain
OPKCENBM_00939 1.9e-164 yxaM EGP Major facilitator Superfamily
OPKCENBM_00940 1.5e-23 S Bacterial toxin of type II toxin-antitoxin system, YafQ
OPKCENBM_00941 3.5e-34 S RelB antitoxin
OPKCENBM_00942 1.1e-67 S AAA domain
OPKCENBM_00943 8.7e-145 2.7.1.89 M Phosphotransferase enzyme family
OPKCENBM_00944 8e-79 3.6.1.55 F NUDIX domain
OPKCENBM_00945 1.1e-114 2.4.2.3 F Phosphorylase superfamily
OPKCENBM_00946 1.2e-140 2.4.2.3 F Phosphorylase superfamily
OPKCENBM_00947 2.1e-140 2.4.2.3 F Phosphorylase superfamily
OPKCENBM_00948 5e-78 6.3.3.2 S ASCH
OPKCENBM_00949 1.3e-78 5.4.2.11 G Phosphoglycerate mutase family
OPKCENBM_00950 9.7e-147 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OPKCENBM_00951 1.8e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
OPKCENBM_00952 1.6e-144 rbsU U ribose uptake protein RbsU
OPKCENBM_00953 7e-147 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
OPKCENBM_00954 7.9e-147 G Transmembrane secretion effector
OPKCENBM_00955 8.6e-36 G Transmembrane secretion effector
OPKCENBM_00956 1.4e-276 V ABC-type multidrug transport system, ATPase and permease components
OPKCENBM_00957 1.3e-250 V ABC-type multidrug transport system, ATPase and permease components
OPKCENBM_00958 9.1e-12 V ABC-type multidrug transport system, ATPase and permease components
OPKCENBM_00959 7.7e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OPKCENBM_00960 1.3e-201 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
OPKCENBM_00961 1.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
OPKCENBM_00962 7.9e-163 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
OPKCENBM_00963 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
OPKCENBM_00964 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OPKCENBM_00965 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OPKCENBM_00966 2.2e-87 ypmB S Protein conserved in bacteria
OPKCENBM_00967 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
OPKCENBM_00968 1.9e-110 dnaD L DnaD domain protein
OPKCENBM_00969 8e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OPKCENBM_00970 1.1e-39 L Helix-turn-helix domain
OPKCENBM_00971 1.3e-21 L PFAM Integrase catalytic region
OPKCENBM_00972 1.5e-52 L PFAM Integrase catalytic region
OPKCENBM_00973 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
OPKCENBM_00974 1.7e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OPKCENBM_00975 3.1e-101 ypsA S Belongs to the UPF0398 family
OPKCENBM_00976 1.5e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OPKCENBM_00977 1.1e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OPKCENBM_00978 1.2e-235 cpdA S Calcineurin-like phosphoesterase
OPKCENBM_00979 2.9e-207 I transferase activity, transferring acyl groups other than amino-acyl groups
OPKCENBM_00980 2e-169 degV S DegV family
OPKCENBM_00981 1.6e-55
OPKCENBM_00982 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
OPKCENBM_00983 3.7e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OPKCENBM_00984 1.8e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OPKCENBM_00985 3.7e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OPKCENBM_00986 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
OPKCENBM_00987 0.0 FbpA K Fibronectin-binding protein
OPKCENBM_00988 1.4e-63
OPKCENBM_00989 1e-162 degV S EDD domain protein, DegV family
OPKCENBM_00990 4.5e-152
OPKCENBM_00991 1.4e-153 K Transcriptional regulator
OPKCENBM_00992 8.3e-204 xerS L Belongs to the 'phage' integrase family
OPKCENBM_00993 7.2e-124 yoaK S Protein of unknown function (DUF1275)
OPKCENBM_00994 1.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OPKCENBM_00995 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
OPKCENBM_00996 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
OPKCENBM_00997 8.2e-179 K Transcriptional regulator
OPKCENBM_00998 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OPKCENBM_00999 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OPKCENBM_01000 1.3e-114 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OPKCENBM_01001 3.5e-106 lacA 2.3.1.79 S Transferase hexapeptide repeat
OPKCENBM_01002 2.1e-165 akr5f 1.1.1.346 S reductase
OPKCENBM_01003 2.2e-140 V ATPases associated with a variety of cellular activities
OPKCENBM_01004 2.6e-233 S ABC-2 family transporter protein
OPKCENBM_01005 2.1e-194
OPKCENBM_01006 8.5e-112 ybhL S Belongs to the BI1 family
OPKCENBM_01007 2.8e-32
OPKCENBM_01008 2.2e-152 4.1.1.45 S Amidohydrolase
OPKCENBM_01009 4.5e-13 rarA L atpase related to the helicase subunit of the holliday junction resolvase
OPKCENBM_01010 5.7e-106 yrvN L AAA C-terminal domain
OPKCENBM_01011 1.1e-46
OPKCENBM_01012 8.4e-13 3.1.1.81 GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OPKCENBM_01014 0.0 S PglZ domain
OPKCENBM_01015 3.6e-23 S Protein of unknown function (DUF3644)
OPKCENBM_01016 2.9e-55 S Protein of unknown function (DUF3644)
OPKCENBM_01018 1.3e-99 LO the current gene model (or a revised gene model) may contain a frame shift
OPKCENBM_01019 0.0 2.1.1.72 LV Eco57I restriction-modification methylase
OPKCENBM_01020 2e-220 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
OPKCENBM_01021 4.3e-85 S Domain of unknown function (DUF1788)
OPKCENBM_01022 1.5e-72 S Putative inner membrane protein (DUF1819)
OPKCENBM_01023 3.8e-55 L Transposase
OPKCENBM_01024 1.6e-13 GM NmrA-like family
OPKCENBM_01026 3.6e-238 yrvN L AAA C-terminal domain
OPKCENBM_01027 1.1e-19 K Transcriptional regulator
OPKCENBM_01028 6.5e-156 C Aldo keto reductase
OPKCENBM_01029 0.0 lmrA 3.6.3.44 V ABC transporter
OPKCENBM_01030 2.6e-71 K helix_turn_helix multiple antibiotic resistance protein
OPKCENBM_01031 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
OPKCENBM_01032 1.5e-76 yphH S Cupin domain
OPKCENBM_01033 1.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OPKCENBM_01034 4e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
OPKCENBM_01036 1.2e-168 uvrA3 L excinuclease ABC, A subunit
OPKCENBM_01037 2.3e-306 uvrA3 L excinuclease ABC, A subunit
OPKCENBM_01038 5.3e-137 S PFAM Archaeal ATPase
OPKCENBM_01039 8.2e-50 S PFAM Archaeal ATPase
OPKCENBM_01040 8.6e-277 L Transposase
OPKCENBM_01041 3.5e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
OPKCENBM_01043 1.4e-138 H Nodulation protein S (NodS)
OPKCENBM_01044 3.2e-270 mntH P H( )-stimulated, divalent metal cation uptake system
OPKCENBM_01045 2.1e-54 yitW S Iron-sulfur cluster assembly protein
OPKCENBM_01046 7.6e-274 sufB O assembly protein SufB
OPKCENBM_01047 2.7e-79 nifU C SUF system FeS assembly protein, NifU family
OPKCENBM_01048 1.1e-231 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OPKCENBM_01049 2.6e-222 sufD O FeS assembly protein SufD
OPKCENBM_01050 5e-145 sufC O FeS assembly ATPase SufC
OPKCENBM_01052 4.8e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OPKCENBM_01053 5e-218 aspC 2.6.1.1 E Aminotransferase
OPKCENBM_01054 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OPKCENBM_01055 1.9e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OPKCENBM_01056 1.3e-191 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OPKCENBM_01057 4.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OPKCENBM_01058 2.1e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OPKCENBM_01059 9.3e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
OPKCENBM_01060 3.3e-186 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OPKCENBM_01061 3.1e-182 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_01062 6e-247 brnQ U Component of the transport system for branched-chain amino acids
OPKCENBM_01063 2.1e-73 S Putative adhesin
OPKCENBM_01064 7.1e-168 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
OPKCENBM_01065 4.2e-86 S Peptidase propeptide and YPEB domain
OPKCENBM_01066 2.9e-238 T GHKL domain
OPKCENBM_01067 4.1e-127 T Transcriptional regulatory protein, C terminal
OPKCENBM_01068 5.3e-118 3.6.1.55 F NUDIX domain
OPKCENBM_01069 1.6e-108 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
OPKCENBM_01071 8.4e-75 S reductase
OPKCENBM_01072 8.4e-109 S Protein of unknown function (DUF1211)
OPKCENBM_01073 3.8e-50 D Domain of Unknown Function (DUF1542)
OPKCENBM_01074 4.4e-71 K LytTr DNA-binding domain
OPKCENBM_01075 5e-64 S Protein of unknown function (DUF3021)
OPKCENBM_01076 1e-128 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
OPKCENBM_01077 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OPKCENBM_01078 3.7e-44 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
OPKCENBM_01079 1.7e-177 MA20_14895 S Conserved hypothetical protein 698
OPKCENBM_01080 7.2e-72
OPKCENBM_01082 3.4e-100 S LexA-binding, inner membrane-associated putative hydrolase
OPKCENBM_01083 3.5e-101 L PFAM Integrase catalytic region
OPKCENBM_01084 2.6e-41 L Helix-turn-helix domain
OPKCENBM_01085 2.4e-91 K LysR substrate binding domain
OPKCENBM_01086 3e-175 lacX 5.1.3.3 G Aldose 1-epimerase
OPKCENBM_01087 2.4e-251 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OPKCENBM_01088 4.3e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OPKCENBM_01089 6.1e-171 xerC D Phage integrase, N-terminal SAM-like domain
OPKCENBM_01090 6.7e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OPKCENBM_01091 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OPKCENBM_01092 4e-153 dprA LU DNA protecting protein DprA
OPKCENBM_01093 2.9e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OPKCENBM_01094 7e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OPKCENBM_01095 3.7e-263 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
OPKCENBM_01096 1.6e-35 yozE S Belongs to the UPF0346 family
OPKCENBM_01097 2.1e-149 DegV S Uncharacterised protein, DegV family COG1307
OPKCENBM_01098 1e-114 hlyIII S protein, hemolysin III
OPKCENBM_01099 2.3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OPKCENBM_01100 1.4e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OPKCENBM_01101 1.1e-285 L Transposase
OPKCENBM_01103 4.8e-132 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_01104 1.2e-67 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_01107 6.3e-09 S SIR2-like domain
OPKCENBM_01108 4.8e-28 S SIR2-like domain
OPKCENBM_01109 5.7e-136 S SIR2-like domain
OPKCENBM_01110 0.0 N Uncharacterized conserved protein (DUF2075)
OPKCENBM_01111 2.5e-228 S Tetratricopeptide repeat protein
OPKCENBM_01112 6.7e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OPKCENBM_01113 5.9e-244 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OPKCENBM_01114 6e-219 rpsA 1.17.7.4 J Ribosomal protein S1
OPKCENBM_01115 2.1e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OPKCENBM_01116 6.4e-97 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OPKCENBM_01117 2.6e-58 M Lysin motif
OPKCENBM_01118 1.2e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OPKCENBM_01119 6.4e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OPKCENBM_01120 6.3e-134 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OPKCENBM_01121 1.8e-62 ribT K acetyltransferase
OPKCENBM_01122 6.3e-165 xerD D recombinase XerD
OPKCENBM_01123 1.2e-166 cvfB S S1 domain
OPKCENBM_01124 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OPKCENBM_01125 3.6e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OPKCENBM_01126 0.0 dnaE 2.7.7.7 L DNA polymerase
OPKCENBM_01127 6.9e-27 S Protein of unknown function (DUF2929)
OPKCENBM_01128 1.1e-305 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
OPKCENBM_01129 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OPKCENBM_01130 9.7e-47 yrvD S Lipopolysaccharide assembly protein A domain
OPKCENBM_01131 1.2e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OPKCENBM_01132 6.8e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OPKCENBM_01133 0.0 oatA I Acyltransferase
OPKCENBM_01134 2.3e-237 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OPKCENBM_01135 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OPKCENBM_01136 1.8e-162 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
OPKCENBM_01137 7.1e-91 dedA 3.1.3.1 S SNARE associated Golgi protein
OPKCENBM_01138 1.9e-104 L PFAM transposase, IS4 family protein
OPKCENBM_01139 4.1e-31 L PFAM transposase, IS4 family protein
OPKCENBM_01142 5.4e-112 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
OPKCENBM_01144 2.7e-194 pts36C G iic component
OPKCENBM_01145 1.8e-08 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
OPKCENBM_01146 6.6e-49 pts36A 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
OPKCENBM_01147 2.4e-56 K DeoR C terminal sensor domain
OPKCENBM_01148 3.6e-81 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
OPKCENBM_01149 3.2e-54 yxeH S hydrolase
OPKCENBM_01150 6e-72 pgm3 G Phosphoglycerate mutase family
OPKCENBM_01151 1.1e-102 L PFAM Integrase catalytic region
OPKCENBM_01152 9e-42 L Helix-turn-helix domain
OPKCENBM_01153 4.1e-31 L PFAM transposase, IS4 family protein
OPKCENBM_01154 1.9e-104 L PFAM transposase, IS4 family protein
OPKCENBM_01155 1.8e-110 xerD L Phage integrase, N-terminal SAM-like domain
OPKCENBM_01156 1.1e-97 GM NmrA-like family
OPKCENBM_01157 1.6e-244 yagE E amino acid
OPKCENBM_01159 1.6e-88 S Rib/alpha-like repeat
OPKCENBM_01160 2.7e-64 S Domain of unknown function DUF1828
OPKCENBM_01161 1e-66
OPKCENBM_01162 9.9e-35
OPKCENBM_01163 2.2e-78 mutT 3.6.1.55 F NUDIX domain
OPKCENBM_01164 6.2e-61
OPKCENBM_01167 2.5e-137 dnaQ 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
OPKCENBM_01168 1.2e-166 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OPKCENBM_01169 4.8e-114 casE S CRISPR_assoc
OPKCENBM_01170 2.4e-66 casD S CRISPR-associated protein (Cas_Cas5)
OPKCENBM_01171 1.4e-111 casC L CT1975-like protein
OPKCENBM_01172 3e-33 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
OPKCENBM_01173 1.6e-145 casA L the current gene model (or a revised gene model) may contain a frame shift
OPKCENBM_01174 5.8e-286 cas3 L CRISPR-associated helicase cas3
OPKCENBM_01175 2e-142 htpX O Peptidase family M48
OPKCENBM_01176 1.8e-69 S HIRAN
OPKCENBM_01178 1.2e-121
OPKCENBM_01183 7.9e-24 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
OPKCENBM_01184 4.5e-103 S Protein of unknown function (DUF3644)
OPKCENBM_01185 4.3e-11 S FRG
OPKCENBM_01187 1e-187 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OPKCENBM_01188 6.7e-118 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
OPKCENBM_01189 2.2e-165 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OPKCENBM_01190 7.8e-207 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OPKCENBM_01191 1.8e-23 L Transposase IS66 family
OPKCENBM_01192 1.1e-150 L Transposase IS66 family
OPKCENBM_01193 3e-18 S Transposase C of IS166 homeodomain
OPKCENBM_01194 1.2e-44 L PFAM IS66 Orf2 family protein
OPKCENBM_01196 1.6e-11 S Acyltransferase family
OPKCENBM_01198 1.4e-176 S Acyltransferase family
OPKCENBM_01199 6.2e-263 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
OPKCENBM_01200 3.2e-172 S Core-2/I-Branching enzyme
OPKCENBM_01201 4.1e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
OPKCENBM_01202 4.5e-71 S Psort location CytoplasmicMembrane, score 9.99
OPKCENBM_01203 9.9e-174 glfT1 1.1.1.133 S Glycosyltransferase like family 2
OPKCENBM_01204 1.8e-206 M Glycosyl transferases group 1
OPKCENBM_01205 2.2e-207 M Glycosyl transferases group 1
OPKCENBM_01206 1.8e-201 M Glycosyl transferases group 1
OPKCENBM_01207 1.6e-148 cps1D M Domain of unknown function (DUF4422)
OPKCENBM_01208 2.9e-114 rfbP M Bacterial sugar transferase
OPKCENBM_01209 3e-139 ywqE 3.1.3.48 GM PHP domain protein
OPKCENBM_01210 8.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
OPKCENBM_01211 1.6e-136 epsB M biosynthesis protein
OPKCENBM_01212 5e-150 brpA K Cell envelope-like function transcriptional attenuator common domain protein
OPKCENBM_01213 1.2e-53 K DNA-templated transcription, initiation
OPKCENBM_01214 3.3e-31
OPKCENBM_01215 1.4e-23
OPKCENBM_01216 9.3e-121 frnE Q DSBA-like thioredoxin domain
OPKCENBM_01217 4.1e-210
OPKCENBM_01218 1.4e-74 S Domain of unknown function (DUF4767)
OPKCENBM_01219 2.9e-111 frnE Q DSBA-like thioredoxin domain
OPKCENBM_01221 5.6e-81
OPKCENBM_01222 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OPKCENBM_01223 1.5e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
OPKCENBM_01224 9.4e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OPKCENBM_01225 7.9e-204 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OPKCENBM_01226 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OPKCENBM_01227 5e-159
OPKCENBM_01228 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OPKCENBM_01229 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OPKCENBM_01230 4.4e-34 rpsT J Binds directly to 16S ribosomal RNA
OPKCENBM_01231 9.8e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
OPKCENBM_01232 0.0 comEC S Competence protein ComEC
OPKCENBM_01233 3.3e-81 comEA L Competence protein ComEA
OPKCENBM_01234 1.4e-184 ylbL T Belongs to the peptidase S16 family
OPKCENBM_01235 3.6e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OPKCENBM_01236 4.7e-94 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
OPKCENBM_01237 7.4e-50 ylbG S UPF0298 protein
OPKCENBM_01238 2.9e-210 ftsW D Belongs to the SEDS family
OPKCENBM_01239 0.0 typA T GTP-binding protein TypA
OPKCENBM_01240 6.8e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OPKCENBM_01241 2.3e-34 ykzG S Belongs to the UPF0356 family
OPKCENBM_01242 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OPKCENBM_01243 1.2e-174 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
OPKCENBM_01244 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OPKCENBM_01245 8.2e-114 S Repeat protein
OPKCENBM_01246 1.4e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
OPKCENBM_01247 4.8e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OPKCENBM_01248 1.1e-56 XK27_04120 S Putative amino acid metabolism
OPKCENBM_01249 7.1e-201 iscS 2.8.1.7 E Aminotransferase class V
OPKCENBM_01250 7.8e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OPKCENBM_01251 1e-31
OPKCENBM_01252 8.2e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
OPKCENBM_01253 2.3e-33 cspA K 'Cold-shock' DNA-binding domain
OPKCENBM_01254 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OPKCENBM_01255 1.4e-112 gpsB D DivIVA domain protein
OPKCENBM_01256 1.4e-144 ylmH S S4 domain protein
OPKCENBM_01257 2.7e-27 yggT S YGGT family
OPKCENBM_01258 1.3e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OPKCENBM_01259 1.1e-235 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OPKCENBM_01260 7.3e-237 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OPKCENBM_01261 7.9e-149 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OPKCENBM_01262 1.2e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OPKCENBM_01263 4.1e-256 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OPKCENBM_01264 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OPKCENBM_01265 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OPKCENBM_01266 4.8e-55 ftsL D Cell division protein FtsL
OPKCENBM_01267 2.1e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OPKCENBM_01268 4.1e-77 mraZ K Belongs to the MraZ family
OPKCENBM_01269 2.7e-52 S Protein of unknown function (DUF3397)
OPKCENBM_01270 3.6e-13 S Protein of unknown function (DUF4044)
OPKCENBM_01271 5e-93 mreD
OPKCENBM_01272 1e-140 mreC M Involved in formation and maintenance of cell shape
OPKCENBM_01273 2.7e-164 mreB D cell shape determining protein MreB
OPKCENBM_01274 3.7e-108 radC L DNA repair protein
OPKCENBM_01275 6.2e-120 S Haloacid dehalogenase-like hydrolase
OPKCENBM_01276 9.7e-228 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OPKCENBM_01277 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OPKCENBM_01278 0.0 3.6.3.8 P P-type ATPase
OPKCENBM_01279 6.8e-169 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
OPKCENBM_01280 1.6e-118 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OPKCENBM_01281 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OPKCENBM_01282 8.6e-215 iscS2 2.8.1.7 E Aminotransferase class V
OPKCENBM_01283 3.1e-285 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OPKCENBM_01285 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OPKCENBM_01286 6.6e-81 yueI S Protein of unknown function (DUF1694)
OPKCENBM_01287 6.4e-235 rarA L recombination factor protein RarA
OPKCENBM_01289 1.5e-80 usp6 T universal stress protein
OPKCENBM_01290 5.2e-223 rodA D Belongs to the SEDS family
OPKCENBM_01291 6.6e-34 S Protein of unknown function (DUF2969)
OPKCENBM_01292 2.6e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
OPKCENBM_01293 1.2e-12 S DNA-directed RNA polymerase subunit beta
OPKCENBM_01294 1.7e-179 mbl D Cell shape determining protein MreB Mrl
OPKCENBM_01295 1.2e-30 ywzB S Protein of unknown function (DUF1146)
OPKCENBM_01296 5.3e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OPKCENBM_01297 9.6e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OPKCENBM_01298 3.5e-169 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OPKCENBM_01299 6.7e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OPKCENBM_01300 1.4e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OPKCENBM_01301 3.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OPKCENBM_01302 4.7e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OPKCENBM_01303 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
OPKCENBM_01304 3.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OPKCENBM_01305 1.6e-185 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OPKCENBM_01306 3.1e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OPKCENBM_01307 6.5e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OPKCENBM_01308 1e-110 tdk 2.7.1.21 F thymidine kinase
OPKCENBM_01309 3.5e-260 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
OPKCENBM_01310 1.9e-276 L Transposase
OPKCENBM_01311 1.4e-187 ampC V Beta-lactamase
OPKCENBM_01314 3.9e-67
OPKCENBM_01315 7.5e-113 EGP Major facilitator Superfamily
OPKCENBM_01316 3.8e-79 EGP Major facilitator Superfamily
OPKCENBM_01317 1.9e-261 pgi 5.3.1.9 G Belongs to the GPI family
OPKCENBM_01318 1.4e-104 vanZ V VanZ like family
OPKCENBM_01319 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
OPKCENBM_01320 3.5e-266 T PhoQ Sensor
OPKCENBM_01321 1.9e-127 K Transcriptional regulatory protein, C terminal
OPKCENBM_01322 1.7e-66 S SdpI/YhfL protein family
OPKCENBM_01323 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
OPKCENBM_01324 3.4e-205 patB 4.4.1.8 E Aminotransferase, class I
OPKCENBM_01325 2.9e-93 M Protein of unknown function (DUF3737)
OPKCENBM_01326 2.5e-284 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
OPKCENBM_01329 5.1e-226 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OPKCENBM_01330 1.2e-183 ytxK 2.1.1.72 L N-6 DNA Methylase
OPKCENBM_01331 1.1e-84 comGF U Putative Competence protein ComGF
OPKCENBM_01332 2.9e-10
OPKCENBM_01333 3.7e-59
OPKCENBM_01334 2.3e-39 comGC U Required for transformation and DNA binding
OPKCENBM_01335 5.4e-173 comGB NU type II secretion system
OPKCENBM_01336 1.5e-180 comGA NU Type II IV secretion system protein
OPKCENBM_01337 1.5e-132 yebC K Transcriptional regulatory protein
OPKCENBM_01338 1.8e-95 S VanZ like family
OPKCENBM_01339 1.5e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OPKCENBM_01340 9.1e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
OPKCENBM_01341 7.5e-146 yisY 1.11.1.10 S Alpha/beta hydrolase family
OPKCENBM_01342 1.5e-113
OPKCENBM_01343 1.2e-198 S Putative adhesin
OPKCENBM_01344 1.2e-61 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OPKCENBM_01345 7.7e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OPKCENBM_01346 2.4e-147 S Sucrose-6F-phosphate phosphohydrolase
OPKCENBM_01347 2.2e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OPKCENBM_01348 3.8e-171 ybbR S YbbR-like protein
OPKCENBM_01349 2.9e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OPKCENBM_01350 1.3e-209 potD P ABC transporter
OPKCENBM_01351 2.9e-137 potC P ABC transporter permease
OPKCENBM_01352 1.2e-130 potB P ABC transporter permease
OPKCENBM_01353 1.2e-202 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
OPKCENBM_01354 4.9e-165 murB 1.3.1.98 M Cell wall formation
OPKCENBM_01355 3.1e-98 dnaQ 2.7.7.7 L DNA polymerase III
OPKCENBM_01356 5.5e-83 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
OPKCENBM_01357 5.1e-176 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
OPKCENBM_01358 6.7e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OPKCENBM_01359 1.1e-153 ycsE S Sucrose-6F-phosphate phosphohydrolase
OPKCENBM_01360 9.2e-92
OPKCENBM_01361 5.4e-77
OPKCENBM_01362 2.1e-105 3.2.2.20 K acetyltransferase
OPKCENBM_01363 8.7e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
OPKCENBM_01364 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OPKCENBM_01365 1.9e-28 secG U Preprotein translocase
OPKCENBM_01366 3.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OPKCENBM_01367 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OPKCENBM_01368 4.6e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OPKCENBM_01369 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OPKCENBM_01370 1.4e-187 cggR K Putative sugar-binding domain
OPKCENBM_01372 1.6e-274 ycaM E amino acid
OPKCENBM_01373 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OPKCENBM_01374 1.8e-170 whiA K May be required for sporulation
OPKCENBM_01375 5.8e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OPKCENBM_01376 4.6e-160 rapZ S Displays ATPase and GTPase activities
OPKCENBM_01377 8.1e-91 S Short repeat of unknown function (DUF308)
OPKCENBM_01378 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OPKCENBM_01379 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OPKCENBM_01380 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
OPKCENBM_01381 1.5e-162 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
OPKCENBM_01382 2.9e-255 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OPKCENBM_01383 6.5e-202 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OPKCENBM_01384 6.5e-158 lacR K Transcriptional regulator
OPKCENBM_01385 1.7e-168 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OPKCENBM_01386 7.7e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OPKCENBM_01387 3.5e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OPKCENBM_01388 5e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OPKCENBM_01390 6.8e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OPKCENBM_01391 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OPKCENBM_01392 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OPKCENBM_01393 5e-122 comFC S Competence protein
OPKCENBM_01394 7.3e-217 comFA L Helicase C-terminal domain protein
OPKCENBM_01395 6.9e-116 yvyE 3.4.13.9 S YigZ family
OPKCENBM_01396 8.6e-191 tagO 2.7.8.33, 2.7.8.35 M transferase
OPKCENBM_01397 6.9e-194 rny S Endoribonuclease that initiates mRNA decay
OPKCENBM_01398 3.5e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OPKCENBM_01399 1.4e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OPKCENBM_01400 1.1e-120 ymfM S Helix-turn-helix domain
OPKCENBM_01401 3.7e-131 IQ Enoyl-(Acyl carrier protein) reductase
OPKCENBM_01402 1.8e-231 S Peptidase M16
OPKCENBM_01403 5e-229 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
OPKCENBM_01404 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OPKCENBM_01405 3.9e-75 WQ51_03320 S Protein of unknown function (DUF1149)
OPKCENBM_01406 1.7e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OPKCENBM_01407 1.8e-207 yubA S AI-2E family transporter
OPKCENBM_01408 1.3e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
OPKCENBM_01409 1e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
OPKCENBM_01410 3.6e-235 N Uncharacterized conserved protein (DUF2075)
OPKCENBM_01411 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
OPKCENBM_01412 3e-154 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OPKCENBM_01413 1.8e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OPKCENBM_01414 5.2e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
OPKCENBM_01415 1.7e-108 yjbK S CYTH
OPKCENBM_01416 6.5e-105 yjbH Q Thioredoxin
OPKCENBM_01417 4.7e-155 coiA 3.6.4.12 S Competence protein
OPKCENBM_01418 1.3e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
OPKCENBM_01419 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OPKCENBM_01420 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OPKCENBM_01421 4.2e-40 ptsH G phosphocarrier protein HPR
OPKCENBM_01422 5.9e-25
OPKCENBM_01423 0.0 clpE O Belongs to the ClpA ClpB family
OPKCENBM_01424 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
OPKCENBM_01425 1.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OPKCENBM_01426 2.6e-155 hlyX S Transporter associated domain
OPKCENBM_01427 1.3e-76
OPKCENBM_01428 5.6e-86
OPKCENBM_01429 7e-112 ygaC J Belongs to the UPF0374 family
OPKCENBM_01430 1.6e-143 recX 2.4.1.337 GT4 S Regulatory protein RecX
OPKCENBM_01431 7.3e-261 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OPKCENBM_01432 8.4e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
OPKCENBM_01433 5.6e-220 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
OPKCENBM_01434 1.1e-212 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
OPKCENBM_01435 1.7e-176 D Alpha beta
OPKCENBM_01437 2e-149 S haloacid dehalogenase-like hydrolase
OPKCENBM_01438 2.2e-205 EGP Major facilitator Superfamily
OPKCENBM_01439 7.1e-261 glnA 6.3.1.2 E glutamine synthetase
OPKCENBM_01440 3.3e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OPKCENBM_01441 8.1e-19 S Protein of unknown function (DUF3042)
OPKCENBM_01442 5.1e-58 yqhL P Rhodanese-like protein
OPKCENBM_01443 7.9e-35 yqgQ S Bacterial protein of unknown function (DUF910)
OPKCENBM_01444 2e-118 gluP 3.4.21.105 S Rhomboid family
OPKCENBM_01445 8.1e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OPKCENBM_01446 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OPKCENBM_01447 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
OPKCENBM_01448 0.0 S membrane
OPKCENBM_01449 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OPKCENBM_01450 1.2e-202 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OPKCENBM_01451 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OPKCENBM_01452 5.5e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OPKCENBM_01453 6.2e-63 yodB K Transcriptional regulator, HxlR family
OPKCENBM_01454 2.8e-137 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OPKCENBM_01455 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OPKCENBM_01456 1.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OPKCENBM_01457 1e-279 arlS 2.7.13.3 T Histidine kinase
OPKCENBM_01458 1.1e-130 K response regulator
OPKCENBM_01459 4.2e-95 yceD S Uncharacterized ACR, COG1399
OPKCENBM_01460 2.9e-218 ylbM S Belongs to the UPF0348 family
OPKCENBM_01461 3.7e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OPKCENBM_01462 2.3e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
OPKCENBM_01463 4.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OPKCENBM_01464 1e-209 yqeH S Ribosome biogenesis GTPase YqeH
OPKCENBM_01465 1.4e-87 yqeG S HAD phosphatase, family IIIA
OPKCENBM_01466 5.5e-59 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OPKCENBM_01467 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OPKCENBM_01468 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OPKCENBM_01469 5.2e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OPKCENBM_01470 1.9e-93 S domain protein
OPKCENBM_01471 5.3e-50 V ABC transporter
OPKCENBM_01472 3.1e-54 V ABC transporter
OPKCENBM_01473 9.1e-37 S Protein of unknown function (DUF3021)
OPKCENBM_01474 1.2e-52 K LytTr DNA-binding domain
OPKCENBM_01475 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OPKCENBM_01476 1.1e-159 dnaI L Primosomal protein DnaI
OPKCENBM_01477 9.6e-242 dnaB L Replication initiation and membrane attachment
OPKCENBM_01478 1.7e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OPKCENBM_01479 4.6e-105 lysA2 M Glycosyl hydrolases family 25
OPKCENBM_01480 1.5e-38 S Bacteriophage holin of superfamily 6 (Holin_LLH)
OPKCENBM_01481 6.2e-12
OPKCENBM_01483 4.5e-54
OPKCENBM_01485 9.1e-60 E GDSL-like Lipase/Acylhydrolase
OPKCENBM_01486 2.8e-50
OPKCENBM_01487 0.0 M Prophage endopeptidase tail
OPKCENBM_01488 4.7e-143 S phage tail
OPKCENBM_01489 0.0 sca1 3.4.21.96 D SLT domain
OPKCENBM_01492 1.7e-94 S Phage tail tube protein
OPKCENBM_01493 1.6e-21
OPKCENBM_01494 1.1e-40 S exonuclease activity
OPKCENBM_01496 4.2e-54 S Phage gp6-like head-tail connector protein
OPKCENBM_01497 1e-157
OPKCENBM_01498 2.3e-67 S Domain of unknown function (DUF4355)
OPKCENBM_01500 1.4e-167 S head morphogenesis protein, SPP1 gp7 family
OPKCENBM_01501 1.8e-259 S Phage portal protein, SPP1 Gp6-like
OPKCENBM_01502 1.6e-230 S Phage terminase, large subunit
OPKCENBM_01503 3.4e-74 xtmA L Terminase small subunit
OPKCENBM_01505 2.4e-105
OPKCENBM_01507 1.2e-07 arpU S Phage transcriptional regulator, ArpU family
OPKCENBM_01513 3.5e-23 S sequence-specific DNA binding
OPKCENBM_01514 1.5e-145 L DnaD domain protein
OPKCENBM_01515 2.2e-111 S ERF superfamily
OPKCENBM_01516 1.9e-55 S Protein of unknown function (DUF1351)
OPKCENBM_01517 3.6e-12
OPKCENBM_01521 1.1e-27
OPKCENBM_01522 1.2e-101 K ORF6N domain
OPKCENBM_01524 1e-10 S sequence-specific DNA binding
OPKCENBM_01525 1.1e-25 1.15.1.2 CE Pfam:DUF955
OPKCENBM_01526 2.1e-16
OPKCENBM_01527 2.8e-32
OPKCENBM_01528 3.4e-102
OPKCENBM_01529 3.9e-79 S Phage integrase family
OPKCENBM_01530 1.9e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OPKCENBM_01531 1.3e-153 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OPKCENBM_01532 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OPKCENBM_01533 1.4e-34
OPKCENBM_01534 8.8e-153 levD G PTS system mannose/fructose/sorbose family IID component
OPKCENBM_01535 9.4e-142 M PTS system sorbose-specific iic component
OPKCENBM_01536 4.3e-94 2.7.1.191 G PTS system sorbose subfamily IIB component
OPKCENBM_01537 4.1e-72 levA G PTS system fructose IIA component
OPKCENBM_01538 4.9e-163 rbsB G Periplasmic binding protein domain
OPKCENBM_01539 1.2e-212 baeS F Sensor histidine kinase
OPKCENBM_01540 4.1e-116 baeR K helix_turn_helix, Lux Regulon
OPKCENBM_01541 3.2e-226 G Bacterial extracellular solute-binding protein
OPKCENBM_01542 4.9e-128 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OPKCENBM_01543 4.8e-115 K UTRA
OPKCENBM_01544 6.9e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OPKCENBM_01545 8.8e-84 cutC P Participates in the control of copper homeostasis
OPKCENBM_01546 4.1e-121 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OPKCENBM_01547 5.6e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OPKCENBM_01548 5.1e-63
OPKCENBM_01549 2e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OPKCENBM_01550 7.6e-222 ecsB U ABC transporter
OPKCENBM_01551 3.7e-134 ecsA V ABC transporter, ATP-binding protein
OPKCENBM_01552 1.6e-76 hit FG Scavenger mRNA decapping enzyme C-term binding
OPKCENBM_01553 1.3e-50
OPKCENBM_01554 1.1e-22 S YtxH-like protein
OPKCENBM_01555 2.1e-147 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OPKCENBM_01556 1.5e-183 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
OPKCENBM_01557 0.0 L AAA domain
OPKCENBM_01558 8.3e-216 yhaO L Ser Thr phosphatase family protein
OPKCENBM_01559 2.8e-55 yheA S Belongs to the UPF0342 family
OPKCENBM_01560 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OPKCENBM_01561 1.2e-149 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OPKCENBM_01563 7.8e-143 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
OPKCENBM_01564 7.5e-194 V Beta-lactamase
OPKCENBM_01565 3.4e-94 ung2 3.2.2.27 L Uracil-DNA glycosylase
OPKCENBM_01566 4.4e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
OPKCENBM_01567 6.1e-94 dps P Belongs to the Dps family
OPKCENBM_01568 4.5e-32 copZ C Heavy-metal-associated domain
OPKCENBM_01569 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
OPKCENBM_01570 1.7e-104
OPKCENBM_01571 5.5e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OPKCENBM_01572 4.6e-115 spaE S ABC-2 family transporter protein
OPKCENBM_01573 2.4e-127 mutF V ABC transporter, ATP-binding protein
OPKCENBM_01574 2.7e-239 nhaC C Na H antiporter NhaC
OPKCENBM_01575 7.6e-152 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
OPKCENBM_01576 3.3e-95 S UPF0397 protein
OPKCENBM_01577 0.0 ykoD P ABC transporter, ATP-binding protein
OPKCENBM_01578 2.4e-142 cbiQ P cobalt transport
OPKCENBM_01579 8.7e-117 ybhL S Belongs to the BI1 family
OPKCENBM_01580 0.0 GT2,GT4 M family 8
OPKCENBM_01581 0.0 GT2,GT4 M family 8
OPKCENBM_01582 1.1e-17 UW Tetratricopeptide repeat
OPKCENBM_01583 2.3e-132 UW Tetratricopeptide repeat
OPKCENBM_01584 2.7e-231 UW Tetratricopeptide repeat
OPKCENBM_01585 7.5e-69 UW Tetratricopeptide repeat
OPKCENBM_01586 9.9e-149 S hydrolase
OPKCENBM_01588 1.1e-167 yegS 2.7.1.107 G Lipid kinase
OPKCENBM_01589 6e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OPKCENBM_01590 2.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OPKCENBM_01591 3.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OPKCENBM_01592 2.2e-207 camS S sex pheromone
OPKCENBM_01593 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OPKCENBM_01594 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OPKCENBM_01595 3.1e-110 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
OPKCENBM_01596 7.6e-101 S ECF transporter, substrate-specific component
OPKCENBM_01598 1.2e-234 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
OPKCENBM_01599 1.2e-184 msmX P Belongs to the ABC transporter superfamily
OPKCENBM_01600 4.2e-154 sacA 3.2.1.26 GH32 G Glycosyl hydrolases family 32
OPKCENBM_01601 3e-132 msmG G Binding-protein-dependent transport system inner membrane component
OPKCENBM_01602 1.2e-152 msmF P ABC-type sugar transport systems, permease components
OPKCENBM_01603 1e-200 G Bacterial extracellular solute-binding protein
OPKCENBM_01604 2.4e-117 msmR K helix_turn _helix lactose operon repressor
OPKCENBM_01605 2.1e-79 ydcK S Belongs to the SprT family
OPKCENBM_01606 8e-131 M Glycosyltransferase sugar-binding region containing DXD motif
OPKCENBM_01607 1.4e-251 epsU S Polysaccharide biosynthesis protein
OPKCENBM_01608 1.2e-208 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
OPKCENBM_01609 4.4e-133
OPKCENBM_01610 3e-279 V ABC transporter transmembrane region
OPKCENBM_01611 0.0 pacL 3.6.3.8 P P-type ATPase
OPKCENBM_01612 3.9e-119 spoVK O ATPase family associated with various cellular activities (AAA)
OPKCENBM_01613 2.5e-218 spoVK O ATPase family associated with various cellular activities (AAA)
OPKCENBM_01614 1.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OPKCENBM_01615 2.7e-282 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OPKCENBM_01616 1.1e-102 L PFAM Integrase catalytic region
OPKCENBM_01617 9e-42 L Helix-turn-helix domain
OPKCENBM_01618 0.0 S Glycosyltransferase like family 2
OPKCENBM_01619 3.2e-198 csaB M Glycosyl transferases group 1
OPKCENBM_01620 1.7e-131 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OPKCENBM_01621 7.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
OPKCENBM_01622 3.6e-123 gntR1 K UTRA
OPKCENBM_01623 3.9e-188
OPKCENBM_01624 2.4e-47 P Rhodanese Homology Domain
OPKCENBM_01627 4.9e-165 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
OPKCENBM_01628 2.2e-111 K SIS domain
OPKCENBM_01629 2.3e-58 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
OPKCENBM_01630 1.2e-169 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
OPKCENBM_01631 2.5e-31 yjgN S Bacterial protein of unknown function (DUF898)
OPKCENBM_01633 2.5e-92 M LysM domain protein
OPKCENBM_01634 2.7e-108 M LysM domain protein
OPKCENBM_01635 2.8e-63 S Putative ABC-transporter type IV
OPKCENBM_01636 1.2e-57 psiE S Phosphate-starvation-inducible E
OPKCENBM_01637 1.1e-87 K acetyltransferase
OPKCENBM_01639 8.2e-162 yvgN C Aldo keto reductase
OPKCENBM_01640 3.2e-245 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
OPKCENBM_01641 6.8e-48 S Uncharacterized protein conserved in bacteria (DUF2263)
OPKCENBM_01642 1.7e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OPKCENBM_01643 0.0 lhr L DEAD DEAH box helicase
OPKCENBM_01644 1.8e-248 P P-loop Domain of unknown function (DUF2791)
OPKCENBM_01645 0.0 S TerB-C domain
OPKCENBM_01646 1.6e-102 4.1.1.44 S Carboxymuconolactone decarboxylase family
OPKCENBM_01647 8.2e-70
OPKCENBM_01648 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
OPKCENBM_01649 2.3e-243 cycA E Amino acid permease
OPKCENBM_01651 3.3e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
OPKCENBM_01652 2.1e-22 S ORF located using Blastx
OPKCENBM_01669 3.3e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
OPKCENBM_01670 2.1e-22 S ORF located using Blastx
OPKCENBM_01671 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
OPKCENBM_01672 2.5e-181 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OPKCENBM_01673 1.2e-196 cpoA GT4 M Glycosyltransferase, group 1 family protein
OPKCENBM_01674 4.3e-214 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
OPKCENBM_01686 1.9e-59
OPKCENBM_01687 6.2e-185 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_01704 3.3e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
OPKCENBM_01705 2.1e-22 S ORF located using Blastx
OPKCENBM_01706 2.5e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OPKCENBM_01707 1.9e-98 J Acetyltransferase (GNAT) domain
OPKCENBM_01708 9e-107 yjbF S SNARE associated Golgi protein
OPKCENBM_01709 4.7e-151 I alpha/beta hydrolase fold
OPKCENBM_01710 7.8e-42 hipB K Helix-turn-helix
OPKCENBM_01711 1.2e-78 hipB K Helix-turn-helix
OPKCENBM_01712 4e-243 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
OPKCENBM_01713 8.3e-153
OPKCENBM_01714 1e-106 S SNARE associated Golgi protein
OPKCENBM_01715 1.2e-111 cof S haloacid dehalogenase-like hydrolase
OPKCENBM_01716 0.0 ydgH S MMPL family
OPKCENBM_01717 5.3e-93 yobS K Bacterial regulatory proteins, tetR family
OPKCENBM_01718 9.7e-148 3.5.2.6 V Beta-lactamase enzyme family
OPKCENBM_01719 1.7e-165 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
OPKCENBM_01720 3.5e-76 yjcF S Acetyltransferase (GNAT) domain
OPKCENBM_01721 2.8e-86 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
OPKCENBM_01722 2.8e-76 yybA 2.3.1.57 K Transcriptional regulator
OPKCENBM_01723 2.9e-39 ypaA S Protein of unknown function (DUF1304)
OPKCENBM_01724 7.4e-239 G Bacterial extracellular solute-binding protein
OPKCENBM_01725 7.4e-247 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
OPKCENBM_01726 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
OPKCENBM_01727 2.1e-157 gtsB P ABC-type sugar transport systems, permease components
OPKCENBM_01728 4.6e-202 malK P ATPases associated with a variety of cellular activities
OPKCENBM_01730 6.9e-275 pipD E Dipeptidase
OPKCENBM_01731 5.6e-206 L Putative transposase DNA-binding domain
OPKCENBM_01732 4.3e-155 endA F DNA RNA non-specific endonuclease
OPKCENBM_01733 7.6e-157 dkg S reductase
OPKCENBM_01734 1.7e-73 ltrA S Bacterial low temperature requirement A protein (LtrA)
OPKCENBM_01735 3.6e-103 ltrA S Bacterial low temperature requirement A protein (LtrA)
OPKCENBM_01736 7.3e-183 dnaQ 2.7.7.7 L EXOIII
OPKCENBM_01737 7.7e-140 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OPKCENBM_01738 6.5e-108 yviA S Protein of unknown function (DUF421)
OPKCENBM_01739 5.8e-74 S Protein of unknown function (DUF3290)
OPKCENBM_01740 4.2e-239 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OPKCENBM_01741 1.4e-90 S PAS domain
OPKCENBM_01742 3.4e-143 pnuC H nicotinamide mononucleotide transporter
OPKCENBM_01743 1.3e-33 M domain protein
OPKCENBM_01744 9.7e-217 GM domain, Protein
OPKCENBM_01745 5.3e-63 GM domain, Protein
OPKCENBM_01746 1.1e-34 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OPKCENBM_01747 1.2e-85 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
OPKCENBM_01748 2e-83
OPKCENBM_01749 1.5e-144 glvR K Helix-turn-helix domain, rpiR family
OPKCENBM_01750 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
OPKCENBM_01751 1.2e-273 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
OPKCENBM_01752 1.8e-133 S PAS domain
OPKCENBM_01753 1.3e-236 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OPKCENBM_01754 4.9e-215 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
OPKCENBM_01755 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OPKCENBM_01756 1.6e-64
OPKCENBM_01757 2.2e-145 G PTS system mannose/fructose/sorbose family IID component
OPKCENBM_01758 3.2e-139 G PTS system sorbose-specific iic component
OPKCENBM_01759 1.1e-159 2.7.1.191 G PTS system sorbose subfamily IIB component
OPKCENBM_01760 0.0 oppA E ABC transporter substrate-binding protein
OPKCENBM_01761 1.8e-154 EG EamA-like transporter family
OPKCENBM_01762 1.6e-160 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OPKCENBM_01763 2.4e-44 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OPKCENBM_01764 2.1e-233 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_01765 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OPKCENBM_01766 1.9e-163 coaA 2.7.1.33 F Pantothenic acid kinase
OPKCENBM_01767 7.1e-101 E GDSL-like Lipase/Acylhydrolase
OPKCENBM_01768 8.3e-123 yvpB S Peptidase_C39 like family
OPKCENBM_01769 0.0 helD 3.6.4.12 L DNA helicase
OPKCENBM_01770 4.3e-115 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
OPKCENBM_01772 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
OPKCENBM_01773 5.8e-141 rpiR1 K Helix-turn-helix domain, rpiR family
OPKCENBM_01774 9e-127 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
OPKCENBM_01775 0.0 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
OPKCENBM_01776 1.2e-148 xth 3.1.11.2 L exodeoxyribonuclease III
OPKCENBM_01777 8.9e-51
OPKCENBM_01778 2.8e-26
OPKCENBM_01779 4.7e-125 pgm3 G Phosphoglycerate mutase family
OPKCENBM_01780 1.4e-302 V FtsX-like permease family
OPKCENBM_01781 5.3e-133 cysA V ABC transporter, ATP-binding protein
OPKCENBM_01782 2.9e-276 E amino acid
OPKCENBM_01783 8e-238 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_01784 3.1e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OPKCENBM_01785 5.3e-231 S Putative peptidoglycan binding domain
OPKCENBM_01786 2.7e-96 M NlpC P60 family protein
OPKCENBM_01787 1.6e-97 gmk2 2.7.4.8 F Guanylate kinase
OPKCENBM_01788 1.5e-43
OPKCENBM_01789 6.8e-268 S O-antigen ligase like membrane protein
OPKCENBM_01790 3.5e-109
OPKCENBM_01791 1.2e-79 nrdI F Belongs to the NrdI family
OPKCENBM_01792 2.8e-163 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OPKCENBM_01793 1.2e-77
OPKCENBM_01794 4.7e-60 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
OPKCENBM_01795 8.9e-40
OPKCENBM_01796 4.8e-79 S Threonine/Serine exporter, ThrE
OPKCENBM_01797 1.9e-136 thrE S Putative threonine/serine exporter
OPKCENBM_01798 8.4e-282 S ABC transporter
OPKCENBM_01799 2.4e-60
OPKCENBM_01800 4.2e-35
OPKCENBM_01801 6.9e-209 brpA K Cell envelope-like function transcriptional attenuator common domain protein
OPKCENBM_01802 0.0 pepF E oligoendopeptidase F
OPKCENBM_01803 2.9e-48 L Helix-turn-helix domain
OPKCENBM_01804 1.9e-192 L COG2963 Transposase and inactivated derivatives
OPKCENBM_01805 4.2e-239 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_01806 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OPKCENBM_01807 7.5e-236 nfrB 2.4.1.336 GT2 M Glycosyltransferase like family 2
OPKCENBM_01809 8.3e-200 EGP Major facilitator Superfamily
OPKCENBM_01810 9e-30 L Helix-turn-helix domain
OPKCENBM_01811 2.4e-33 L PFAM Integrase catalytic region
OPKCENBM_01812 3.1e-257 lctP C L-lactate permease
OPKCENBM_01813 8.7e-134 znuB U ABC 3 transport family
OPKCENBM_01814 7.3e-118 fhuC P ABC transporter
OPKCENBM_01815 5.6e-153 psaA P Belongs to the bacterial solute-binding protein 9 family
OPKCENBM_01816 2.1e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
OPKCENBM_01817 1.3e-137 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
OPKCENBM_01818 0.0 2.7.7.7 M domain protein
OPKCENBM_01819 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
OPKCENBM_01820 1.2e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
OPKCENBM_01821 5.8e-135 fruR K DeoR C terminal sensor domain
OPKCENBM_01823 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
OPKCENBM_01824 1.5e-220 natB CP ABC-2 family transporter protein
OPKCENBM_01825 1.3e-162 natA S ABC transporter, ATP-binding protein
OPKCENBM_01826 1.2e-143 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
OPKCENBM_01827 7.7e-307 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OPKCENBM_01828 1.7e-202 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
OPKCENBM_01829 7.4e-121 K response regulator
OPKCENBM_01830 0.0 V ABC transporter
OPKCENBM_01831 3.9e-296 V ABC transporter, ATP-binding protein
OPKCENBM_01832 6e-133 XK27_01040 S Protein of unknown function (DUF1129)
OPKCENBM_01833 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OPKCENBM_01834 7.2e-42 yyzM S Bacterial protein of unknown function (DUF951)
OPKCENBM_01835 9.4e-153 spo0J K Belongs to the ParB family
OPKCENBM_01836 2.8e-137 soj D Sporulation initiation inhibitor
OPKCENBM_01837 3.3e-142 noc K Belongs to the ParB family
OPKCENBM_01838 2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
OPKCENBM_01839 1.4e-95 cvpA S Colicin V production protein
OPKCENBM_01840 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
OPKCENBM_01841 6.3e-148 3.1.3.48 T Tyrosine phosphatase family
OPKCENBM_01842 8.9e-195 4.2.1.126 S Bacterial protein of unknown function (DUF871)
OPKCENBM_01843 1.2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
OPKCENBM_01844 6.4e-96 nqr 1.5.1.36 S reductase
OPKCENBM_01845 3.2e-175 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
OPKCENBM_01846 3.6e-106 K WHG domain
OPKCENBM_01847 2.3e-37
OPKCENBM_01848 1.7e-265 pipD E Dipeptidase
OPKCENBM_01849 1.9e-116 devA 3.6.3.25 V ABC transporter, ATP-binding protein
OPKCENBM_01850 2.2e-180 hrtB V ABC transporter permease
OPKCENBM_01851 4.6e-83 ygfC K Bacterial regulatory proteins, tetR family
OPKCENBM_01852 2.6e-106 G phosphoglycerate mutase
OPKCENBM_01853 7.9e-114 G Phosphoglycerate mutase family
OPKCENBM_01854 2.6e-135 aroD S Alpha/beta hydrolase family
OPKCENBM_01855 4.9e-134 S Belongs to the UPF0246 family
OPKCENBM_01856 5.5e-51
OPKCENBM_01857 2e-126
OPKCENBM_01858 1e-37 L Helix-turn-helix domain
OPKCENBM_01859 1.5e-101 L PFAM Integrase catalytic region
OPKCENBM_01860 5.8e-158 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OPKCENBM_01861 1.1e-306 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
OPKCENBM_01862 2.4e-136 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
OPKCENBM_01863 7.9e-149 ybbH_2 K Helix-turn-helix domain, rpiR family
OPKCENBM_01864 7.7e-151 2.7.7.12 C Domain of unknown function (DUF4931)
OPKCENBM_01865 5.8e-68 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
OPKCENBM_01866 8.9e-156
OPKCENBM_01867 4.1e-215 mdtG EGP Major facilitator Superfamily
OPKCENBM_01868 3.9e-122 puuD S peptidase C26
OPKCENBM_01869 2.3e-290 V ABC transporter transmembrane region
OPKCENBM_01870 3.9e-87 ymdB S Macro domain protein
OPKCENBM_01871 9.5e-15
OPKCENBM_01873 4.8e-155 V ABC transporter transmembrane region
OPKCENBM_01874 4.2e-60 KLT Protein kinase domain
OPKCENBM_01876 0.0 scrA 2.7.1.199, 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
OPKCENBM_01877 1.9e-299 scrB 3.2.1.26 GH32 G invertase
OPKCENBM_01878 3e-184 scrR K Transcriptional regulator, LacI family
OPKCENBM_01879 3.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
OPKCENBM_01880 1.7e-148 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OPKCENBM_01881 2.3e-130 cobQ S glutamine amidotransferase
OPKCENBM_01882 3.5e-255 yfnA E Amino Acid
OPKCENBM_01883 1.9e-161 EG EamA-like transporter family
OPKCENBM_01884 1.6e-188 asnA 6.3.1.1 F aspartate--ammonia ligase
OPKCENBM_01885 7.7e-234 steT_1 E amino acid
OPKCENBM_01886 8e-134 puuD S peptidase C26
OPKCENBM_01887 1.5e-218 yifK E Amino acid permease
OPKCENBM_01888 1.5e-253 yifK E Amino acid permease
OPKCENBM_01889 1.8e-65 manO S Domain of unknown function (DUF956)
OPKCENBM_01890 1.1e-172 manN G system, mannose fructose sorbose family IID component
OPKCENBM_01891 1.3e-124 manY G PTS system
OPKCENBM_01892 1.2e-183 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
OPKCENBM_01894 3.3e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
OPKCENBM_01895 2.1e-22 S ORF located using Blastx
OPKCENBM_01899 3.3e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
OPKCENBM_01900 2.1e-22 S ORF located using Blastx
OPKCENBM_01904 3.3e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
OPKCENBM_01905 2.1e-22 S ORF located using Blastx
OPKCENBM_01908 9.3e-248 yfnA E Amino Acid
OPKCENBM_01909 1.1e-102 L PFAM Integrase catalytic region
OPKCENBM_01910 2.6e-41 L Helix-turn-helix domain
OPKCENBM_01911 0.0 clpE2 O AAA domain (Cdc48 subfamily)
OPKCENBM_01912 2.9e-165 S Alpha/beta hydrolase of unknown function (DUF915)
OPKCENBM_01913 6.4e-230 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPKCENBM_01914 5.4e-39
OPKCENBM_01915 8.4e-213 lmrP E Major Facilitator Superfamily
OPKCENBM_01916 2.2e-137 pbpX2 V Beta-lactamase
OPKCENBM_01917 3.8e-251 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OPKCENBM_01918 6.7e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OPKCENBM_01919 1.4e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
OPKCENBM_01920 2.8e-290 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OPKCENBM_01922 3e-39
OPKCENBM_01923 4.1e-201 ywhK S Membrane
OPKCENBM_01924 1.9e-276 L Transposase
OPKCENBM_01925 1.9e-194 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPKCENBM_01926 6.9e-77 K Helix-turn-helix domain, rpiR family
OPKCENBM_01927 6.6e-241 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OPKCENBM_01928 2.3e-84 ykuL S (CBS) domain
OPKCENBM_01929 0.0 cadA P P-type ATPase
OPKCENBM_01930 1.4e-196 napA P Sodium/hydrogen exchanger family
OPKCENBM_01931 5.6e-86 S Putative adhesin
OPKCENBM_01932 1.1e-273 V ABC transporter transmembrane region
OPKCENBM_01933 7.2e-158 mutR K Helix-turn-helix XRE-family like proteins
OPKCENBM_01934 8.7e-34
OPKCENBM_01935 1.9e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OPKCENBM_01936 5.6e-156 S Protein of unknown function (DUF979)
OPKCENBM_01937 2.8e-112 S Protein of unknown function (DUF969)
OPKCENBM_01938 3e-76 S Protein of unknown function (DUF805)
OPKCENBM_01940 4.1e-15
OPKCENBM_01941 7.9e-266 G PTS system Galactitol-specific IIC component
OPKCENBM_01942 2.4e-92 S Protein of unknown function (DUF1440)
OPKCENBM_01943 2e-104 S CAAX protease self-immunity
OPKCENBM_01944 2.2e-83 S DUF218 domain
OPKCENBM_01945 3.3e-74 S DUF218 domain
OPKCENBM_01946 0.0 macB_3 V ABC transporter, ATP-binding protein
OPKCENBM_01947 1.1e-269 cydA 1.10.3.14 C ubiquinol oxidase
OPKCENBM_01948 2e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
OPKCENBM_01949 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
OPKCENBM_01950 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OPKCENBM_01951 8.3e-176 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
OPKCENBM_01952 1.4e-54 G Bacterial extracellular solute-binding protein
OPKCENBM_01953 8.3e-150 G Bacterial extracellular solute-binding protein
OPKCENBM_01954 3.7e-168 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
OPKCENBM_01955 2.8e-199 tcsA S ABC transporter substrate-binding protein PnrA-like
OPKCENBM_01956 2.6e-41 L Helix-turn-helix domain
OPKCENBM_01957 1.5e-101 L PFAM Integrase catalytic region
OPKCENBM_01958 1.5e-147 K Helix-turn-helix domain, rpiR family
OPKCENBM_01959 2.9e-164 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
OPKCENBM_01960 8.3e-149 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OPKCENBM_01961 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OPKCENBM_01962 5.2e-128 S membrane transporter protein
OPKCENBM_01963 1.7e-156 yeaE S Aldo/keto reductase family
OPKCENBM_01964 5.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OPKCENBM_01965 4.7e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
OPKCENBM_01966 2.4e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
OPKCENBM_01967 1.2e-235 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
OPKCENBM_01968 3e-232 pbuG S permease
OPKCENBM_01969 2.7e-110 K helix_turn_helix, mercury resistance
OPKCENBM_01970 2e-231 pbuG S permease
OPKCENBM_01971 2.1e-225 pbuG S permease
OPKCENBM_01972 2.9e-14 K Bacteriophage CI repressor helix-turn-helix domain
OPKCENBM_01973 3.9e-18 K Bacteriophage CI repressor helix-turn-helix domain
OPKCENBM_01974 1.5e-68 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
OPKCENBM_01975 6.3e-83
OPKCENBM_01976 8.7e-88
OPKCENBM_01977 2e-71 atkY K Penicillinase repressor
OPKCENBM_01978 1.7e-63 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
OPKCENBM_01979 2.2e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
OPKCENBM_01980 0.0 copA 3.6.3.54 P P-type ATPase
OPKCENBM_01981 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
OPKCENBM_01983 3.2e-156 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OPKCENBM_01985 2.9e-17 M Glycosyl transferase family group 2
OPKCENBM_01986 1.2e-59 M Glycosyl transferase family group 2
OPKCENBM_01988 2.3e-281 E Amino acid permease
OPKCENBM_01989 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
OPKCENBM_01990 8.5e-248 ynbB 4.4.1.1 P aluminum resistance
OPKCENBM_01991 2.1e-70 K Acetyltransferase (GNAT) domain
OPKCENBM_01992 3.3e-102 EGP Sugar (and other) transporter
OPKCENBM_01993 3.6e-97 EGP Sugar (and other) transporter
OPKCENBM_01994 3.3e-68 S Iron-sulphur cluster biosynthesis
OPKCENBM_01995 3.2e-11 S RelB antitoxin
OPKCENBM_01996 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OPKCENBM_01997 2.5e-286 clcA P chloride
OPKCENBM_01998 6e-271 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OPKCENBM_01999 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OPKCENBM_02000 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OPKCENBM_02001 6.8e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OPKCENBM_02002 1.6e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OPKCENBM_02003 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
OPKCENBM_02004 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)