ORF_ID e_value Gene_name EC_number CAZy COGs Description
NEHDFDCK_00001 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
NEHDFDCK_00002 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
NEHDFDCK_00003 4e-60
NEHDFDCK_00004 1.7e-73
NEHDFDCK_00005 5e-82 yybC S Protein of unknown function (DUF2798)
NEHDFDCK_00006 1.8e-44
NEHDFDCK_00007 5.2e-47
NEHDFDCK_00008 4.6e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NEHDFDCK_00009 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
NEHDFDCK_00010 2.4e-144 yjfP S Dienelactone hydrolase family
NEHDFDCK_00011 6.4e-69
NEHDFDCK_00012 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NEHDFDCK_00013 5.5e-46
NEHDFDCK_00014 6e-58
NEHDFDCK_00015 2.3e-164
NEHDFDCK_00016 1.3e-72 K Transcriptional regulator
NEHDFDCK_00017 0.0 pepF2 E Oligopeptidase F
NEHDFDCK_00018 4.5e-174 D Alpha beta
NEHDFDCK_00019 1.2e-45 S Enterocin A Immunity
NEHDFDCK_00020 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
NEHDFDCK_00021 5.1e-125 skfE V ABC transporter
NEHDFDCK_00022 2.7e-132
NEHDFDCK_00023 3.7e-107 pncA Q Isochorismatase family
NEHDFDCK_00024 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEHDFDCK_00025 0.0 yjcE P Sodium proton antiporter
NEHDFDCK_00026 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
NEHDFDCK_00027 2.7e-177 S Oxidoreductase family, NAD-binding Rossmann fold
NEHDFDCK_00028 8e-157 K Helix-turn-helix domain, rpiR family
NEHDFDCK_00029 6.4e-176 ccpB 5.1.1.1 K lacI family
NEHDFDCK_00030 4.2e-141 S Sucrose-6F-phosphate phosphohydrolase
NEHDFDCK_00031 1.5e-124 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
NEHDFDCK_00032 1.8e-178 K sugar-binding domain protein
NEHDFDCK_00033 0.0 ybiW 2.3.1.54 C Pyruvate formate lyase-like
NEHDFDCK_00034 3.7e-134 yciT K DeoR C terminal sensor domain
NEHDFDCK_00035 3.7e-156 pflC 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEHDFDCK_00036 6.2e-165 bglK_1 GK ROK family
NEHDFDCK_00037 3.7e-154 glcU U sugar transport
NEHDFDCK_00038 5e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEHDFDCK_00039 2.7e-177 iunH2 3.2.2.1 F nucleoside hydrolase
NEHDFDCK_00040 2.5e-98 drgA C Nitroreductase family
NEHDFDCK_00041 3.6e-168 S Polyphosphate kinase 2 (PPK2)
NEHDFDCK_00042 3.4e-180 3.6.4.13 S domain, Protein
NEHDFDCK_00043 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
NEHDFDCK_00044 2.3e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NEHDFDCK_00045 0.0 glpQ 3.1.4.46 C phosphodiesterase
NEHDFDCK_00046 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NEHDFDCK_00047 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
NEHDFDCK_00048 5.7e-288 M domain protein
NEHDFDCK_00049 0.0 ydgH S MMPL family
NEHDFDCK_00050 5.4e-112 S Protein of unknown function (DUF1211)
NEHDFDCK_00051 3.7e-34
NEHDFDCK_00052 2.6e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEHDFDCK_00053 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEHDFDCK_00054 3.5e-13 rmeB K transcriptional regulator, MerR family
NEHDFDCK_00055 3.4e-50 S Domain of unknown function (DU1801)
NEHDFDCK_00056 7.6e-166 corA P CorA-like Mg2+ transporter protein
NEHDFDCK_00057 2.5e-214 ysaA V RDD family
NEHDFDCK_00058 1.7e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
NEHDFDCK_00059 5e-215 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NEHDFDCK_00060 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NEHDFDCK_00061 1.2e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NEHDFDCK_00062 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NEHDFDCK_00063 5.9e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NEHDFDCK_00064 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NEHDFDCK_00065 3.8e-134 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NEHDFDCK_00066 2.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NEHDFDCK_00067 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
NEHDFDCK_00068 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NEHDFDCK_00069 2.4e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NEHDFDCK_00070 4.8e-137 terC P membrane
NEHDFDCK_00071 4.2e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
NEHDFDCK_00072 7.4e-258 npr 1.11.1.1 C NADH oxidase
NEHDFDCK_00073 2.6e-138 XK27_08845 S ABC transporter, ATP-binding protein
NEHDFDCK_00074 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NEHDFDCK_00075 1.4e-176 XK27_08835 S ABC transporter
NEHDFDCK_00076 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NEHDFDCK_00077 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NEHDFDCK_00078 1.5e-231 hom1 1.1.1.3 E Homoserine dehydrogenase
NEHDFDCK_00079 3.3e-161 degV S Uncharacterised protein, DegV family COG1307
NEHDFDCK_00080 6.2e-190 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEHDFDCK_00081 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
NEHDFDCK_00082 2.7e-39
NEHDFDCK_00083 5.8e-82 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEHDFDCK_00084 2e-106 3.2.2.20 K acetyltransferase
NEHDFDCK_00085 7.8e-296 S ABC transporter, ATP-binding protein
NEHDFDCK_00086 1.3e-61 L Transposase and inactivated derivatives, IS30 family
NEHDFDCK_00087 1e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEHDFDCK_00088 2.1e-154 K CAT RNA binding domain
NEHDFDCK_00089 7.9e-258 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
NEHDFDCK_00090 3.7e-142 G YdjC-like protein
NEHDFDCK_00091 8.3e-246 steT E amino acid
NEHDFDCK_00092 5.7e-74 mgrA K helix_turn_helix multiple antibiotic resistance protein
NEHDFDCK_00093 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
NEHDFDCK_00094 2.8e-70 K MarR family
NEHDFDCK_00095 1.1e-209 EGP Major facilitator Superfamily
NEHDFDCK_00096 3.8e-85 S membrane transporter protein
NEHDFDCK_00097 1.5e-95 K Bacterial regulatory proteins, tetR family
NEHDFDCK_00098 9.6e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEHDFDCK_00099 2.9e-78 3.6.1.55 F NUDIX domain
NEHDFDCK_00100 6.5e-48 sugE U Multidrug resistance protein
NEHDFDCK_00101 1.2e-26
NEHDFDCK_00102 5.5e-129 pgm3 G Phosphoglycerate mutase family
NEHDFDCK_00103 4.7e-125 pgm3 G Phosphoglycerate mutase family
NEHDFDCK_00104 0.0 yjbQ P TrkA C-terminal domain protein
NEHDFDCK_00105 1.6e-177 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
NEHDFDCK_00106 9.2e-158 bglG3 K CAT RNA binding domain
NEHDFDCK_00107 0.0 2.7.1.193, 2.7.1.211 G phosphotransferase system
NEHDFDCK_00108 8.7e-300 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NEHDFDCK_00109 1.4e-110 dedA S SNARE associated Golgi protein
NEHDFDCK_00110 0.0 helD 3.6.4.12 L DNA helicase
NEHDFDCK_00111 5e-165 fabK 1.3.1.9 S Nitronate monooxygenase
NEHDFDCK_00112 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
NEHDFDCK_00113 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NEHDFDCK_00114 6.2e-50
NEHDFDCK_00115 4.9e-63 K Helix-turn-helix XRE-family like proteins
NEHDFDCK_00116 0.0 L AAA domain
NEHDFDCK_00117 3.2e-116 XK27_07075 V CAAX protease self-immunity
NEHDFDCK_00118 3.8e-57 hxlR K HxlR-like helix-turn-helix
NEHDFDCK_00119 3.2e-234 EGP Major facilitator Superfamily
NEHDFDCK_00120 3.1e-153 S Cysteine-rich secretory protein family
NEHDFDCK_00121 2.2e-37 S MORN repeat
NEHDFDCK_00122 0.0 XK27_09800 I Acyltransferase family
NEHDFDCK_00123 7.1e-37 S Transglycosylase associated protein
NEHDFDCK_00124 2.6e-84
NEHDFDCK_00125 7.2e-23
NEHDFDCK_00126 8.7e-72 asp S Asp23 family, cell envelope-related function
NEHDFDCK_00127 5.3e-72 asp2 S Asp23 family, cell envelope-related function
NEHDFDCK_00128 9.1e-147 Q Fumarylacetoacetate (FAA) hydrolase family
NEHDFDCK_00129 3.7e-161 yjdB S Domain of unknown function (DUF4767)
NEHDFDCK_00130 3.4e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
NEHDFDCK_00131 4.1e-101 G Glycogen debranching enzyme
NEHDFDCK_00132 0.0 pepN 3.4.11.2 E aminopeptidase
NEHDFDCK_00133 0.0 N Uncharacterized conserved protein (DUF2075)
NEHDFDCK_00134 3.7e-39 S MazG-like family
NEHDFDCK_00135 8.9e-90 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
NEHDFDCK_00136 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
NEHDFDCK_00138 3.5e-88 S AAA domain
NEHDFDCK_00139 4.5e-140 K sequence-specific DNA binding
NEHDFDCK_00140 2.3e-96 K Helix-turn-helix domain
NEHDFDCK_00141 6.1e-171 K Transcriptional regulator
NEHDFDCK_00142 0.0 1.3.5.4 C FMN_bind
NEHDFDCK_00144 2.3e-81 rmaD K Transcriptional regulator
NEHDFDCK_00145 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NEHDFDCK_00146 2.8e-254 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NEHDFDCK_00147 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
NEHDFDCK_00148 6.7e-278 pipD E Dipeptidase
NEHDFDCK_00149 8.6e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NEHDFDCK_00150 3.2e-40
NEHDFDCK_00151 4.1e-32 L leucine-zipper of insertion element IS481
NEHDFDCK_00152 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NEHDFDCK_00153 8.4e-162 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NEHDFDCK_00154 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
NEHDFDCK_00155 4.3e-138 S NADPH-dependent FMN reductase
NEHDFDCK_00156 5.6e-178
NEHDFDCK_00157 3.7e-219 yibE S overlaps another CDS with the same product name
NEHDFDCK_00158 3.4e-127 yibF S overlaps another CDS with the same product name
NEHDFDCK_00159 5.7e-103 3.2.2.20 K FR47-like protein
NEHDFDCK_00160 5e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NEHDFDCK_00161 5.6e-49
NEHDFDCK_00162 9e-192 nlhH_1 I alpha/beta hydrolase fold
NEHDFDCK_00163 6.1e-255 xylP2 G symporter
NEHDFDCK_00164 5.2e-281 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEHDFDCK_00165 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
NEHDFDCK_00166 0.0 asnB 6.3.5.4 E Asparagine synthase
NEHDFDCK_00167 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
NEHDFDCK_00168 1.3e-120 azlC E branched-chain amino acid
NEHDFDCK_00169 4.4e-35 yyaN K MerR HTH family regulatory protein
NEHDFDCK_00170 3.1e-07 yyaN K MerR HTH family regulatory protein
NEHDFDCK_00171 1.4e-75 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHDFDCK_00172 2.2e-38 yaaL S Protein of unknown function (DUF2508)
NEHDFDCK_00173 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEHDFDCK_00174 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NEHDFDCK_00175 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEHDFDCK_00176 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEHDFDCK_00177 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
NEHDFDCK_00178 6.5e-37 nrdH O Glutaredoxin
NEHDFDCK_00179 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEHDFDCK_00180 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEHDFDCK_00181 2.1e-108 yvdD 3.2.2.10 S Belongs to the LOG family
NEHDFDCK_00182 3.6e-40 K Helix-turn-helix domain
NEHDFDCK_00183 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEHDFDCK_00184 1.2e-38 L nuclease
NEHDFDCK_00185 4.6e-177 F DNA/RNA non-specific endonuclease
NEHDFDCK_00186 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NEHDFDCK_00187 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NEHDFDCK_00188 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NEHDFDCK_00189 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NEHDFDCK_00190 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
NEHDFDCK_00191 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
NEHDFDCK_00192 3.4e-28 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NEHDFDCK_00193 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NEHDFDCK_00194 2.4e-101 sigH K Sigma-70 region 2
NEHDFDCK_00195 5.3e-98 yacP S YacP-like NYN domain
NEHDFDCK_00196 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEHDFDCK_00197 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NEHDFDCK_00198 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NEHDFDCK_00199 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEHDFDCK_00200 3.7e-205 yacL S domain protein
NEHDFDCK_00201 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEHDFDCK_00202 1.1e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NEHDFDCK_00203 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
NEHDFDCK_00204 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NEHDFDCK_00205 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
NEHDFDCK_00206 5.2e-113 zmp2 O Zinc-dependent metalloprotease
NEHDFDCK_00207 9.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEHDFDCK_00208 8.3e-177 EG EamA-like transporter family
NEHDFDCK_00209 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
NEHDFDCK_00210 4.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NEHDFDCK_00211 4.1e-136 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
NEHDFDCK_00212 3.7e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NEHDFDCK_00213 7.5e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
NEHDFDCK_00214 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
NEHDFDCK_00215 7.8e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEHDFDCK_00216 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
NEHDFDCK_00217 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
NEHDFDCK_00218 0.0 levR K Sigma-54 interaction domain
NEHDFDCK_00219 4.7e-64 S Domain of unknown function (DUF956)
NEHDFDCK_00220 4.4e-169 manN G system, mannose fructose sorbose family IID component
NEHDFDCK_00221 3.4e-133 manY G PTS system
NEHDFDCK_00222 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NEHDFDCK_00223 2.1e-151 G Peptidase_C39 like family
NEHDFDCK_00225 2.9e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NEHDFDCK_00226 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NEHDFDCK_00227 1.2e-82 ydcK S Belongs to the SprT family
NEHDFDCK_00228 0.0 yhgF K Tex-like protein N-terminal domain protein
NEHDFDCK_00229 8.9e-72
NEHDFDCK_00230 0.0 pacL 3.6.3.8 P P-type ATPase
NEHDFDCK_00231 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NEHDFDCK_00232 1.5e-288 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEHDFDCK_00233 1.2e-137 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NEHDFDCK_00234 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
NEHDFDCK_00235 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NEHDFDCK_00236 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEHDFDCK_00237 3.7e-151 pnuC H nicotinamide mononucleotide transporter
NEHDFDCK_00238 1.2e-192 ybiR P Citrate transporter
NEHDFDCK_00239 1.4e-166 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
NEHDFDCK_00240 2.5e-53 S Cupin domain
NEHDFDCK_00241 3.5e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
NEHDFDCK_00243 9.7e-47
NEHDFDCK_00244 3.1e-27
NEHDFDCK_00245 1.1e-62
NEHDFDCK_00246 2.2e-273 S Virulence-associated protein E
NEHDFDCK_00247 6.4e-137 L Primase C terminal 1 (PriCT-1)
NEHDFDCK_00248 9.6e-30
NEHDFDCK_00249 1.7e-19
NEHDFDCK_00251 8.5e-42
NEHDFDCK_00252 8.8e-82 S Phage regulatory protein Rha (Phage_pRha)
NEHDFDCK_00253 4e-10
NEHDFDCK_00255 9.9e-179 sip L Belongs to the 'phage' integrase family
NEHDFDCK_00258 2e-151 yjjH S Calcineurin-like phosphoesterase
NEHDFDCK_00259 3e-252 dtpT U amino acid peptide transporter
NEHDFDCK_00263 4.6e-163 K Transcriptional regulator
NEHDFDCK_00264 7e-161 akr5f 1.1.1.346 S reductase
NEHDFDCK_00265 9.5e-166 S Oxidoreductase, aldo keto reductase family protein
NEHDFDCK_00266 3e-78 K Winged helix DNA-binding domain
NEHDFDCK_00267 2.2e-268 ycaM E amino acid
NEHDFDCK_00268 8.3e-129 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
NEHDFDCK_00269 1.7e-31
NEHDFDCK_00270 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
NEHDFDCK_00271 0.0 M Bacterial Ig-like domain (group 3)
NEHDFDCK_00272 1.1e-77 fld C Flavodoxin
NEHDFDCK_00273 5.3e-234
NEHDFDCK_00274 4.6e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
NEHDFDCK_00275 2.1e-151 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NEHDFDCK_00276 8.3e-152 EG EamA-like transporter family
NEHDFDCK_00277 4.2e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEHDFDCK_00278 9.8e-152 S hydrolase
NEHDFDCK_00279 4.1e-81
NEHDFDCK_00280 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NEHDFDCK_00281 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
NEHDFDCK_00282 1.8e-130 gntR K UTRA
NEHDFDCK_00283 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NEHDFDCK_00284 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
NEHDFDCK_00285 9.5e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NEHDFDCK_00286 9.8e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NEHDFDCK_00287 8.2e-246 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NEHDFDCK_00288 6.9e-133 V AAA domain, putative AbiEii toxin, Type IV TA system
NEHDFDCK_00289 2e-153 V ABC transporter
NEHDFDCK_00290 1.3e-117 K Transcriptional regulator
NEHDFDCK_00291 6.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEHDFDCK_00292 3.6e-88 niaR S 3H domain
NEHDFDCK_00293 3.9e-224 EGP Major facilitator Superfamily
NEHDFDCK_00294 2.1e-232 S Sterol carrier protein domain
NEHDFDCK_00295 4.2e-211 S Bacterial protein of unknown function (DUF871)
NEHDFDCK_00296 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
NEHDFDCK_00297 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
NEHDFDCK_00298 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
NEHDFDCK_00299 1.1e-101 3.6.1.13 L Belongs to the Nudix hydrolase family
NEHDFDCK_00300 1.7e-111 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NEHDFDCK_00301 4.4e-11 mcbG S Pentapeptide repeats (8 copies)
NEHDFDCK_00302 5e-145 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
NEHDFDCK_00303 5.2e-281 thrC 4.2.3.1 E Threonine synthase
NEHDFDCK_00304 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NEHDFDCK_00306 1.5e-52
NEHDFDCK_00307 3.5e-117
NEHDFDCK_00308 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
NEHDFDCK_00309 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
NEHDFDCK_00311 5e-51
NEHDFDCK_00312 2.8e-87
NEHDFDCK_00313 2.1e-70 gtcA S Teichoic acid glycosylation protein
NEHDFDCK_00314 4e-34
NEHDFDCK_00315 6.7e-81 uspA T universal stress protein
NEHDFDCK_00316 5.8e-149
NEHDFDCK_00317 6.7e-151 V ABC transporter, ATP-binding protein
NEHDFDCK_00318 7.9e-61 gntR1 K Transcriptional regulator, GntR family
NEHDFDCK_00319 8e-42
NEHDFDCK_00320 0.0 V FtsX-like permease family
NEHDFDCK_00321 1.7e-139 cysA V ABC transporter, ATP-binding protein
NEHDFDCK_00322 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
NEHDFDCK_00323 7.5e-149 S Alpha/beta hydrolase of unknown function (DUF915)
NEHDFDCK_00324 9.2e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
NEHDFDCK_00325 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
NEHDFDCK_00326 1.3e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
NEHDFDCK_00327 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
NEHDFDCK_00328 1.5e-223 XK27_09615 1.3.5.4 S reductase
NEHDFDCK_00329 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NEHDFDCK_00330 7.4e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NEHDFDCK_00331 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NEHDFDCK_00332 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEHDFDCK_00333 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEHDFDCK_00334 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEHDFDCK_00335 1.1e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NEHDFDCK_00336 3.8e-190 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NEHDFDCK_00337 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NEHDFDCK_00338 1e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NEHDFDCK_00339 9.3e-215 purD 6.3.4.13 F Belongs to the GARS family
NEHDFDCK_00340 3.9e-127 2.1.1.14 E Methionine synthase
NEHDFDCK_00341 4.6e-252 pgaC GT2 M Glycosyl transferase
NEHDFDCK_00342 2.6e-94
NEHDFDCK_00343 3.1e-74 T EAL domain
NEHDFDCK_00344 2.3e-94
NEHDFDCK_00345 0.0 typA T GTP-binding protein TypA
NEHDFDCK_00346 6.3e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NEHDFDCK_00347 3.3e-46 yktA S Belongs to the UPF0223 family
NEHDFDCK_00348 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
NEHDFDCK_00349 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
NEHDFDCK_00350 5.2e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NEHDFDCK_00351 4.5e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NEHDFDCK_00352 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NEHDFDCK_00353 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEHDFDCK_00354 1.6e-85
NEHDFDCK_00355 3.1e-33 ykzG S Belongs to the UPF0356 family
NEHDFDCK_00356 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEHDFDCK_00357 1.7e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NEHDFDCK_00358 1.7e-28
NEHDFDCK_00359 4.1e-108 mltD CBM50 M NlpC P60 family protein
NEHDFDCK_00360 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEHDFDCK_00361 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NEHDFDCK_00362 1.6e-120 S Repeat protein
NEHDFDCK_00363 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NEHDFDCK_00364 1.3e-263 N domain, Protein
NEHDFDCK_00365 3.7e-193 S Bacterial protein of unknown function (DUF916)
NEHDFDCK_00366 2.3e-120 N WxL domain surface cell wall-binding
NEHDFDCK_00367 2.6e-115 ktrA P domain protein
NEHDFDCK_00368 1.3e-241 ktrB P Potassium uptake protein
NEHDFDCK_00369 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NEHDFDCK_00370 4.9e-57 XK27_04120 S Putative amino acid metabolism
NEHDFDCK_00371 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
NEHDFDCK_00372 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NEHDFDCK_00373 4.6e-28
NEHDFDCK_00374 5.6e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NEHDFDCK_00375 3.2e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NEHDFDCK_00376 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEHDFDCK_00377 1.2e-86 divIVA D DivIVA domain protein
NEHDFDCK_00378 1.3e-145 ylmH S S4 domain protein
NEHDFDCK_00379 1.2e-36 yggT S YGGT family
NEHDFDCK_00380 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NEHDFDCK_00381 2.8e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NEHDFDCK_00382 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NEHDFDCK_00383 1.7e-162 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NEHDFDCK_00384 1.5e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NEHDFDCK_00385 1.4e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEHDFDCK_00386 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEHDFDCK_00387 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NEHDFDCK_00388 7.5e-54 ftsL D Cell division protein FtsL
NEHDFDCK_00389 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEHDFDCK_00390 1.9e-77 mraZ K Belongs to the MraZ family
NEHDFDCK_00391 1.9e-62 S Protein of unknown function (DUF3397)
NEHDFDCK_00392 1.2e-174 corA P CorA-like Mg2+ transporter protein
NEHDFDCK_00393 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NEHDFDCK_00394 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NEHDFDCK_00395 5.3e-113 ywnB S NAD(P)H-binding
NEHDFDCK_00396 2.2e-209 brnQ U Component of the transport system for branched-chain amino acids
NEHDFDCK_00398 2.4e-161 rrmA 2.1.1.187 H Methyltransferase
NEHDFDCK_00399 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEHDFDCK_00400 4.3e-206 XK27_05220 S AI-2E family transporter
NEHDFDCK_00401 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NEHDFDCK_00402 7.4e-194 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NEHDFDCK_00403 5.1e-116 cutC P Participates in the control of copper homeostasis
NEHDFDCK_00404 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NEHDFDCK_00405 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEHDFDCK_00406 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
NEHDFDCK_00407 3.6e-114 yjbH Q Thioredoxin
NEHDFDCK_00408 0.0 pepF E oligoendopeptidase F
NEHDFDCK_00409 7.6e-205 coiA 3.6.4.12 S Competence protein
NEHDFDCK_00410 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NEHDFDCK_00411 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NEHDFDCK_00412 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
NEHDFDCK_00413 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NEHDFDCK_00423 5.5e-08
NEHDFDCK_00435 8.3e-165 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEHDFDCK_00436 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NEHDFDCK_00437 7.6e-205 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NEHDFDCK_00438 1.9e-184 ywhK S Membrane
NEHDFDCK_00439 2.3e-164 degV S Uncharacterised protein, DegV family COG1307
NEHDFDCK_00440 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NEHDFDCK_00441 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEHDFDCK_00442 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEHDFDCK_00443 1.2e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEHDFDCK_00444 6.3e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEHDFDCK_00445 4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEHDFDCK_00446 1.5e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEHDFDCK_00447 3.5e-142 cad S FMN_bind
NEHDFDCK_00448 0.0 ndh 1.6.99.3 C NADH dehydrogenase
NEHDFDCK_00449 1.4e-86 ynhH S NusG domain II
NEHDFDCK_00450 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
NEHDFDCK_00451 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NEHDFDCK_00452 2.1e-61 rplQ J Ribosomal protein L17
NEHDFDCK_00453 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEHDFDCK_00454 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NEHDFDCK_00455 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NEHDFDCK_00456 3.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEHDFDCK_00457 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEHDFDCK_00458 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEHDFDCK_00459 6.3e-70 rplO J Binds to the 23S rRNA
NEHDFDCK_00460 2.2e-24 rpmD J Ribosomal protein L30
NEHDFDCK_00461 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEHDFDCK_00462 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NEHDFDCK_00463 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NEHDFDCK_00464 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NEHDFDCK_00465 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NEHDFDCK_00466 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NEHDFDCK_00467 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NEHDFDCK_00468 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NEHDFDCK_00469 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
NEHDFDCK_00470 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NEHDFDCK_00471 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NEHDFDCK_00472 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NEHDFDCK_00473 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NEHDFDCK_00474 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NEHDFDCK_00475 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NEHDFDCK_00476 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
NEHDFDCK_00477 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NEHDFDCK_00478 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NEHDFDCK_00479 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NEHDFDCK_00480 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NEHDFDCK_00481 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NEHDFDCK_00482 3.2e-116 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NEHDFDCK_00483 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEHDFDCK_00484 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEHDFDCK_00485 4.3e-109 K Bacterial regulatory proteins, tetR family
NEHDFDCK_00486 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEHDFDCK_00487 6.9e-78 ctsR K Belongs to the CtsR family
NEHDFDCK_00495 2.7e-217 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEHDFDCK_00496 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NEHDFDCK_00497 2.5e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NEHDFDCK_00498 1.5e-264 lysP E amino acid
NEHDFDCK_00499 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NEHDFDCK_00500 4.2e-92 K Transcriptional regulator
NEHDFDCK_00501 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
NEHDFDCK_00502 2e-154 I alpha/beta hydrolase fold
NEHDFDCK_00503 2.3e-119 lssY 3.6.1.27 I phosphatase
NEHDFDCK_00504 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NEHDFDCK_00505 2.2e-76 S Threonine/Serine exporter, ThrE
NEHDFDCK_00506 1.5e-130 thrE S Putative threonine/serine exporter
NEHDFDCK_00507 6e-31 cspC K Cold shock protein
NEHDFDCK_00508 2e-120 sirR K iron dependent repressor
NEHDFDCK_00509 5.8e-58
NEHDFDCK_00510 1.7e-84 merR K MerR HTH family regulatory protein
NEHDFDCK_00511 7e-270 lmrB EGP Major facilitator Superfamily
NEHDFDCK_00512 1.4e-117 S Domain of unknown function (DUF4811)
NEHDFDCK_00513 1.2e-29 lytE M LysM domain protein
NEHDFDCK_00514 9.7e-67 gcvH E Glycine cleavage H-protein
NEHDFDCK_00515 6.2e-90 sepS16B
NEHDFDCK_00516 2.9e-64 sepS16B
NEHDFDCK_00517 1.3e-131
NEHDFDCK_00518 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
NEHDFDCK_00519 6.8e-57
NEHDFDCK_00520 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEHDFDCK_00521 2.5e-77 elaA S GNAT family
NEHDFDCK_00522 1.9e-74 K Transcriptional regulator
NEHDFDCK_00523 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
NEHDFDCK_00524 6.2e-39
NEHDFDCK_00525 4e-206 potD P ABC transporter
NEHDFDCK_00526 3.4e-141 potC P ABC transporter permease
NEHDFDCK_00527 2e-149 potB P ABC transporter permease
NEHDFDCK_00528 3.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NEHDFDCK_00529 5e-96 puuR K Cupin domain
NEHDFDCK_00530 1.1e-83 6.3.3.2 S ASCH
NEHDFDCK_00531 1e-84 K GNAT family
NEHDFDCK_00532 1.1e-89 K acetyltransferase
NEHDFDCK_00533 8.1e-22
NEHDFDCK_00534 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
NEHDFDCK_00535 2e-163 ytrB V ABC transporter
NEHDFDCK_00536 4.9e-190
NEHDFDCK_00537 3.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
NEHDFDCK_00538 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NEHDFDCK_00540 3.4e-239 xylP1 G MFS/sugar transport protein
NEHDFDCK_00541 3e-122 qmcA O prohibitin homologues
NEHDFDCK_00542 1.5e-29
NEHDFDCK_00543 1.7e-281 pipD E Dipeptidase
NEHDFDCK_00544 3e-40
NEHDFDCK_00545 6.8e-96 bioY S BioY family
NEHDFDCK_00546 1.9e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NEHDFDCK_00547 1.4e-51 S CHY zinc finger
NEHDFDCK_00548 2.2e-111 metQ P NLPA lipoprotein
NEHDFDCK_00549 6.7e-126 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEHDFDCK_00550 1.1e-86 metI U Binding-protein-dependent transport system inner membrane component
NEHDFDCK_00551 7.7e-148 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEHDFDCK_00552 3.3e-222 mtnE 2.6.1.83 E Aminotransferase
NEHDFDCK_00553 3.8e-218
NEHDFDCK_00554 3.5e-154 tagG U Transport permease protein
NEHDFDCK_00555 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NEHDFDCK_00556 8.4e-44
NEHDFDCK_00557 3.9e-93 K Transcriptional regulator PadR-like family
NEHDFDCK_00558 7.9e-258 P Major Facilitator Superfamily
NEHDFDCK_00559 2.3e-240 amtB P ammonium transporter
NEHDFDCK_00560 5e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NEHDFDCK_00561 3.7e-44
NEHDFDCK_00562 2e-100 zmp1 O Zinc-dependent metalloprotease
NEHDFDCK_00563 1.8e-119 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NEHDFDCK_00564 4.6e-309 mco Q Multicopper oxidase
NEHDFDCK_00565 1.1e-54 ypaA S Protein of unknown function (DUF1304)
NEHDFDCK_00566 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
NEHDFDCK_00567 1.6e-232 flhF N Uncharacterized conserved protein (DUF2075)
NEHDFDCK_00568 1.6e-82 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
NEHDFDCK_00569 9.3e-80
NEHDFDCK_00570 1.4e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NEHDFDCK_00571 4.5e-174 rihC 3.2.2.1 F Nucleoside
NEHDFDCK_00572 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHDFDCK_00573 6.1e-155
NEHDFDCK_00574 3.2e-172
NEHDFDCK_00575 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
NEHDFDCK_00576 1.8e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NEHDFDCK_00577 2.9e-179 proV E ABC transporter, ATP-binding protein
NEHDFDCK_00578 2.2e-254 gshR 1.8.1.7 C Pyridine nucleotide-disulphide oxidoreductase
NEHDFDCK_00579 5.1e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEHDFDCK_00580 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
NEHDFDCK_00581 1.8e-122 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NEHDFDCK_00582 3.1e-222 M domain protein
NEHDFDCK_00583 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
NEHDFDCK_00584 9.4e-231 ymfF S Peptidase M16 inactive domain protein
NEHDFDCK_00585 2.9e-251 ymfH S Peptidase M16
NEHDFDCK_00586 5.7e-110 ymfM S Helix-turn-helix domain
NEHDFDCK_00587 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEHDFDCK_00588 9.4e-231 cinA 3.5.1.42 S Belongs to the CinA family
NEHDFDCK_00589 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEHDFDCK_00590 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
NEHDFDCK_00591 2.7e-154 ymdB S YmdB-like protein
NEHDFDCK_00592 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NEHDFDCK_00593 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NEHDFDCK_00594 1.3e-72
NEHDFDCK_00595 0.0 S Bacterial membrane protein YfhO
NEHDFDCK_00596 3.2e-92
NEHDFDCK_00597 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEHDFDCK_00598 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEHDFDCK_00599 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NEHDFDCK_00600 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEHDFDCK_00601 2.8e-29 yajC U Preprotein translocase
NEHDFDCK_00602 5.9e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEHDFDCK_00603 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NEHDFDCK_00604 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NEHDFDCK_00605 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEHDFDCK_00606 2.4e-43 yrzL S Belongs to the UPF0297 family
NEHDFDCK_00607 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NEHDFDCK_00608 1.6e-48 yrzB S Belongs to the UPF0473 family
NEHDFDCK_00609 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NEHDFDCK_00610 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NEHDFDCK_00611 7.3e-52 trxA O Belongs to the thioredoxin family
NEHDFDCK_00612 1.9e-92 yslB S Protein of unknown function (DUF2507)
NEHDFDCK_00613 4.1e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NEHDFDCK_00614 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEHDFDCK_00615 1.2e-94 S Phosphoesterase
NEHDFDCK_00616 6.5e-87 ykuL S (CBS) domain
NEHDFDCK_00617 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NEHDFDCK_00618 1.7e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NEHDFDCK_00619 2.6e-158 ykuT M mechanosensitive ion channel
NEHDFDCK_00620 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NEHDFDCK_00621 2.8e-56
NEHDFDCK_00622 7.2e-80 K helix_turn_helix, mercury resistance
NEHDFDCK_00623 1.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NEHDFDCK_00624 1.9e-181 ccpA K catabolite control protein A
NEHDFDCK_00625 2.3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
NEHDFDCK_00626 1.7e-48 S DsrE/DsrF-like family
NEHDFDCK_00627 8.3e-131 yebC K Transcriptional regulatory protein
NEHDFDCK_00628 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEHDFDCK_00629 2.1e-174 comGA NU Type II IV secretion system protein
NEHDFDCK_00630 7.4e-189 comGB NU type II secretion system
NEHDFDCK_00631 5.5e-43 comGC U competence protein ComGC
NEHDFDCK_00632 3.2e-83 gspG NU general secretion pathway protein
NEHDFDCK_00633 8.6e-20
NEHDFDCK_00634 6.5e-87 S Prokaryotic N-terminal methylation motif
NEHDFDCK_00636 4.2e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
NEHDFDCK_00637 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEHDFDCK_00638 1.2e-252 cycA E Amino acid permease
NEHDFDCK_00639 8.2e-116 S Calcineurin-like phosphoesterase
NEHDFDCK_00640 3.9e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NEHDFDCK_00641 1.5e-80 yutD S Protein of unknown function (DUF1027)
NEHDFDCK_00642 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NEHDFDCK_00643 4.6e-117 S Protein of unknown function (DUF1461)
NEHDFDCK_00644 3e-119 dedA S SNARE-like domain protein
NEHDFDCK_00645 9.4e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEHDFDCK_00646 1.6e-75 yugI 5.3.1.9 J general stress protein
NEHDFDCK_00647 1e-63
NEHDFDCK_00648 2.4e-22 plnF
NEHDFDCK_00649 4.3e-22
NEHDFDCK_00650 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NEHDFDCK_00651 8.9e-243 mesE M Transport protein ComB
NEHDFDCK_00652 5.9e-110 S CAAX protease self-immunity
NEHDFDCK_00653 1.7e-15 ypbD S CAAX protease self-immunity
NEHDFDCK_00654 2e-68 ypbD S CAAX protease self-immunity
NEHDFDCK_00655 8.4e-100 V CAAX protease self-immunity
NEHDFDCK_00656 1e-114 S CAAX protease self-immunity
NEHDFDCK_00657 5.2e-30
NEHDFDCK_00658 0.0 helD 3.6.4.12 L DNA helicase
NEHDFDCK_00659 1.1e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NEHDFDCK_00660 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NEHDFDCK_00661 1.2e-126 K UbiC transcription regulator-associated domain protein
NEHDFDCK_00662 2.5e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHDFDCK_00663 3.9e-24
NEHDFDCK_00664 2.6e-76 S Domain of unknown function (DUF3284)
NEHDFDCK_00665 5.7e-250 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHDFDCK_00666 7.5e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NEHDFDCK_00667 5.9e-163 GK ROK family
NEHDFDCK_00668 4.1e-133 K Helix-turn-helix domain, rpiR family
NEHDFDCK_00669 1.4e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEHDFDCK_00670 3.1e-167 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NEHDFDCK_00671 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NEHDFDCK_00672 3.1e-178
NEHDFDCK_00673 3.9e-133 cobB K SIR2 family
NEHDFDCK_00674 2e-160 yunF F Protein of unknown function DUF72
NEHDFDCK_00675 2.6e-70 mutT 3.6.1.55 F DNA mismatch repair protein MutT
NEHDFDCK_00676 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEHDFDCK_00677 1.3e-213 bcr1 EGP Major facilitator Superfamily
NEHDFDCK_00678 1.5e-146 tatD L hydrolase, TatD family
NEHDFDCK_00679 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NEHDFDCK_00680 8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NEHDFDCK_00681 3.2e-37 veg S Biofilm formation stimulator VEG
NEHDFDCK_00682 2.2e-162 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NEHDFDCK_00683 1.5e-180 S Prolyl oligopeptidase family
NEHDFDCK_00684 2.8e-128 fhuC 3.6.3.35 P ABC transporter
NEHDFDCK_00685 9.2e-131 znuB U ABC 3 transport family
NEHDFDCK_00686 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NEHDFDCK_00687 1.2e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NEHDFDCK_00688 1.8e-150 bla1 3.5.2.6 V Beta-lactamase enzyme family
NEHDFDCK_00689 2.7e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEHDFDCK_00690 2.5e-181 S DUF218 domain
NEHDFDCK_00691 4.1e-125
NEHDFDCK_00692 4.9e-148 yxeH S hydrolase
NEHDFDCK_00693 9e-264 ywfO S HD domain protein
NEHDFDCK_00694 1.8e-153 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
NEHDFDCK_00695 3.8e-78 ywiB S Domain of unknown function (DUF1934)
NEHDFDCK_00696 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NEHDFDCK_00697 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEHDFDCK_00698 4e-245 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEHDFDCK_00699 3.1e-229 tdcC E amino acid
NEHDFDCK_00700 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NEHDFDCK_00701 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NEHDFDCK_00702 6.4e-131 S YheO-like PAS domain
NEHDFDCK_00703 2.5e-26
NEHDFDCK_00704 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEHDFDCK_00705 6.6e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NEHDFDCK_00706 7.8e-41 rpmE2 J Ribosomal protein L31
NEHDFDCK_00707 1.3e-147 S Bacterial membrane protein, YfhO
NEHDFDCK_00708 4.1e-226 nupG F Nucleoside
NEHDFDCK_00709 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NEHDFDCK_00710 2.7e-149 noc K Belongs to the ParB family
NEHDFDCK_00711 1.8e-136 soj D Sporulation initiation inhibitor
NEHDFDCK_00712 4.8e-157 spo0J K Belongs to the ParB family
NEHDFDCK_00713 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
NEHDFDCK_00714 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEHDFDCK_00715 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
NEHDFDCK_00716 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEHDFDCK_00717 2.6e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NEHDFDCK_00718 5.5e-124 yoaK S Protein of unknown function (DUF1275)
NEHDFDCK_00719 3.2e-124 K response regulator
NEHDFDCK_00720 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
NEHDFDCK_00721 4.2e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NEHDFDCK_00722 2.9e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
NEHDFDCK_00723 5.1e-131 azlC E branched-chain amino acid
NEHDFDCK_00724 2.3e-54 azlD S branched-chain amino acid
NEHDFDCK_00725 1.8e-109 S membrane transporter protein
NEHDFDCK_00726 4.1e-54
NEHDFDCK_00728 1.5e-74 S Psort location Cytoplasmic, score
NEHDFDCK_00729 6e-97 S Domain of unknown function (DUF4352)
NEHDFDCK_00730 2.9e-23 S Protein of unknown function (DUF4064)
NEHDFDCK_00731 2.3e-28 KLT Protein tyrosine kinase
NEHDFDCK_00732 6.2e-145 KLT Protein tyrosine kinase
NEHDFDCK_00733 1.8e-162
NEHDFDCK_00734 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NEHDFDCK_00735 2.4e-83
NEHDFDCK_00736 2.9e-210 xylR GK ROK family
NEHDFDCK_00737 1.9e-171 K AI-2E family transporter
NEHDFDCK_00738 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEHDFDCK_00739 7.4e-31
NEHDFDCK_00740 3.7e-131 L Transposase and inactivated derivatives, IS30 family
NEHDFDCK_00741 6.5e-29 L Transposase and inactivated derivatives, IS30 family
NEHDFDCK_00742 1.2e-71 dptF L COG0433 Predicted ATPase
NEHDFDCK_00743 1.9e-56 dptG
NEHDFDCK_00744 6.9e-259 S Domain of unknown function DUF87
NEHDFDCK_00746 1.7e-18
NEHDFDCK_00748 2.8e-20 polA 2.7.7.7 L 3'-5' exonuclease
NEHDFDCK_00750 9.8e-116 S Phage plasmid primase, P4
NEHDFDCK_00752 6.8e-60 L Phage integrase SAM-like domain
NEHDFDCK_00755 1.2e-09 S Mor transcription activator family
NEHDFDCK_00756 6e-16
NEHDFDCK_00757 4.5e-23 S Mor transcription activator family
NEHDFDCK_00758 1e-29
NEHDFDCK_00759 1.2e-10 S Mor transcription activator family
NEHDFDCK_00760 1.3e-76
NEHDFDCK_00761 4e-41
NEHDFDCK_00762 5.1e-36 3.1.3.16 S Protein of unknown function (DUF1643)
NEHDFDCK_00763 7.1e-137 L Phage integrase SAM-like domain
NEHDFDCK_00764 0.0 L Restriction endonuclease
NEHDFDCK_00765 2.3e-32 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEHDFDCK_00766 1.7e-52 M Lysin motif
NEHDFDCK_00767 1e-120 S CAAX protease self-immunity
NEHDFDCK_00768 2.5e-114 V CAAX protease self-immunity
NEHDFDCK_00769 7.1e-121 yclH V ABC transporter
NEHDFDCK_00770 1.7e-194 yclI V MacB-like periplasmic core domain
NEHDFDCK_00771 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
NEHDFDCK_00772 1e-107 tag 3.2.2.20 L glycosylase
NEHDFDCK_00773 0.0 ydgH S MMPL family
NEHDFDCK_00774 3.1e-104 K transcriptional regulator
NEHDFDCK_00775 2.7e-123 2.7.6.5 S RelA SpoT domain protein
NEHDFDCK_00776 1.3e-47
NEHDFDCK_00777 6.4e-257 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
NEHDFDCK_00778 7.2e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NEHDFDCK_00779 2.1e-41
NEHDFDCK_00780 9.9e-57
NEHDFDCK_00781 2.2e-120 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHDFDCK_00782 2.2e-111 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHDFDCK_00783 2.1e-129 yidA K Helix-turn-helix domain, rpiR family
NEHDFDCK_00784 1.8e-49
NEHDFDCK_00785 4.4e-129 K Transcriptional regulatory protein, C terminal
NEHDFDCK_00786 6.8e-251 T PhoQ Sensor
NEHDFDCK_00787 9.5e-65 K helix_turn_helix, mercury resistance
NEHDFDCK_00788 9.7e-253 ydiC1 EGP Major facilitator Superfamily
NEHDFDCK_00789 1e-40
NEHDFDCK_00790 5.2e-42
NEHDFDCK_00791 5.5e-118
NEHDFDCK_00792 8.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
NEHDFDCK_00793 4.3e-121 K Bacterial regulatory proteins, tetR family
NEHDFDCK_00794 1.8e-72 K Transcriptional regulator
NEHDFDCK_00795 1.6e-70
NEHDFDCK_00796 6.3e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NEHDFDCK_00797 1.4e-144
NEHDFDCK_00798 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
NEHDFDCK_00799 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
NEHDFDCK_00800 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NEHDFDCK_00801 3.5e-129 treR K UTRA
NEHDFDCK_00802 3.7e-42
NEHDFDCK_00803 7.3e-43 S Protein of unknown function (DUF2089)
NEHDFDCK_00804 9.5e-141 pnuC H nicotinamide mononucleotide transporter
NEHDFDCK_00805 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
NEHDFDCK_00806 2.2e-165 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NEHDFDCK_00807 1.4e-209 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NEHDFDCK_00808 2.7e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
NEHDFDCK_00809 4.2e-97 yieF S NADPH-dependent FMN reductase
NEHDFDCK_00810 4.9e-254 S Uncharacterized protein conserved in bacteria (DUF2252)
NEHDFDCK_00811 3.9e-81 ndk 2.7.4.6 F Belongs to the NDK family
NEHDFDCK_00812 2.9e-61
NEHDFDCK_00813 2.5e-95
NEHDFDCK_00814 1.2e-49
NEHDFDCK_00815 6.2e-57 trxA1 O Belongs to the thioredoxin family
NEHDFDCK_00816 2.9e-75
NEHDFDCK_00817 9.5e-222 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
NEHDFDCK_00818 6.6e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHDFDCK_00819 0.0 mtlR K Mga helix-turn-helix domain
NEHDFDCK_00820 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
NEHDFDCK_00821 2.6e-277 pipD E Dipeptidase
NEHDFDCK_00822 3.1e-98 K Helix-turn-helix domain
NEHDFDCK_00823 2.7e-224 1.3.5.4 C FAD dependent oxidoreductase
NEHDFDCK_00824 1e-173 P Major Facilitator Superfamily
NEHDFDCK_00825 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEHDFDCK_00826 2.4e-66
NEHDFDCK_00827 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEHDFDCK_00828 4.1e-158 dkgB S reductase
NEHDFDCK_00829 2.4e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NEHDFDCK_00830 3.1e-101 S ABC transporter permease
NEHDFDCK_00831 6.9e-259 P ABC transporter
NEHDFDCK_00832 3.1e-108 P cobalt transport
NEHDFDCK_00833 9.5e-262 S ATPases associated with a variety of cellular activities
NEHDFDCK_00834 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEHDFDCK_00835 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEHDFDCK_00837 1.7e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEHDFDCK_00838 4e-164 FbpA K Domain of unknown function (DUF814)
NEHDFDCK_00839 1.3e-60 S Domain of unknown function (DU1801)
NEHDFDCK_00840 4.9e-34
NEHDFDCK_00841 1e-179 yghZ C Aldo keto reductase family protein
NEHDFDCK_00842 8.7e-113 pgm1 G phosphoglycerate mutase
NEHDFDCK_00843 7.8e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NEHDFDCK_00844 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHDFDCK_00845 1.3e-78 yiaC K Acetyltransferase (GNAT) domain
NEHDFDCK_00846 1.8e-309 oppA E ABC transporter, substratebinding protein
NEHDFDCK_00847 0.0 oppA E ABC transporter, substratebinding protein
NEHDFDCK_00848 1e-156 hipB K Helix-turn-helix
NEHDFDCK_00850 0.0 3.6.4.13 M domain protein
NEHDFDCK_00851 7.7e-166 mleR K LysR substrate binding domain
NEHDFDCK_00852 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
NEHDFDCK_00853 1.1e-217 nhaC C Na H antiporter NhaC
NEHDFDCK_00854 1.3e-165 3.5.1.10 C nadph quinone reductase
NEHDFDCK_00855 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
NEHDFDCK_00856 1.5e-172 scrR K Transcriptional regulator, LacI family
NEHDFDCK_00857 2.4e-302 scrB 3.2.1.26 GH32 G invertase
NEHDFDCK_00858 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
NEHDFDCK_00859 0.0 rafA 3.2.1.22 G alpha-galactosidase
NEHDFDCK_00860 3.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NEHDFDCK_00861 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
NEHDFDCK_00862 0.0 3.2.1.96 G Glycosyl hydrolase family 85
NEHDFDCK_00863 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NEHDFDCK_00864 4e-209 msmK P Belongs to the ABC transporter superfamily
NEHDFDCK_00865 1.5e-258 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
NEHDFDCK_00866 5.3e-150 malA S maltodextrose utilization protein MalA
NEHDFDCK_00867 1.4e-161 malD P ABC transporter permease
NEHDFDCK_00868 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
NEHDFDCK_00869 2.7e-230 mdxE G Bacterial extracellular solute-binding protein
NEHDFDCK_00870 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
NEHDFDCK_00871 5.7e-180 yvdE K helix_turn _helix lactose operon repressor
NEHDFDCK_00872 2.9e-190 malR K Transcriptional regulator, LacI family
NEHDFDCK_00873 8.6e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NEHDFDCK_00874 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
NEHDFDCK_00875 1.9e-101 dhaL 2.7.1.121 S Dak2
NEHDFDCK_00876 2.5e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NEHDFDCK_00877 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NEHDFDCK_00878 1.1e-92 K Bacterial regulatory proteins, tetR family
NEHDFDCK_00879 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
NEHDFDCK_00880 1.2e-275 C Electron transfer flavoprotein FAD-binding domain
NEHDFDCK_00881 1.2e-115 K Transcriptional regulator
NEHDFDCK_00882 4.6e-299 M Exporter of polyketide antibiotics
NEHDFDCK_00883 6.7e-170 yjjC V ABC transporter
NEHDFDCK_00884 1.2e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
NEHDFDCK_00885 9.1e-89
NEHDFDCK_00886 4.7e-151
NEHDFDCK_00887 2.5e-83
NEHDFDCK_00888 1.8e-44
NEHDFDCK_00889 8.3e-54 K Transcriptional regulator PadR-like family
NEHDFDCK_00890 1.6e-129 K UbiC transcription regulator-associated domain protein
NEHDFDCK_00891 2.5e-98 S UPF0397 protein
NEHDFDCK_00892 0.0 ykoD P ABC transporter, ATP-binding protein
NEHDFDCK_00893 7.1e-150 cbiQ P cobalt transport
NEHDFDCK_00894 8.9e-69 C Oxidoreductase
NEHDFDCK_00895 6.3e-128 C Oxidoreductase
NEHDFDCK_00896 7.8e-256
NEHDFDCK_00897 3.7e-47
NEHDFDCK_00898 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
NEHDFDCK_00899 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
NEHDFDCK_00900 1.2e-165 1.1.1.65 C Aldo keto reductase
NEHDFDCK_00901 7.6e-160 S reductase
NEHDFDCK_00903 2e-89 yeaN P Transporter, major facilitator family protein
NEHDFDCK_00904 1.6e-106 yeaN P Transporter, major facilitator family protein
NEHDFDCK_00905 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
NEHDFDCK_00906 4.7e-227 mdtG EGP Major facilitator Superfamily
NEHDFDCK_00907 5.8e-82 S Protein of unknown function (DUF3021)
NEHDFDCK_00908 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
NEHDFDCK_00909 1.2e-74 papX3 K Transcriptional regulator
NEHDFDCK_00910 1.3e-110 S NADPH-dependent FMN reductase
NEHDFDCK_00911 1.6e-28 KT PspC domain
NEHDFDCK_00912 0.0 pacL1 P P-type ATPase
NEHDFDCK_00913 1.3e-98 S CRISPR-associated protein (Cas_Csn2)
NEHDFDCK_00914 6.3e-48 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NEHDFDCK_00915 2.4e-156 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NEHDFDCK_00916 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NEHDFDCK_00917 1.1e-149 ydjP I Alpha/beta hydrolase family
NEHDFDCK_00918 2.6e-121
NEHDFDCK_00919 2.6e-250 yifK E Amino acid permease
NEHDFDCK_00920 3.4e-85 F NUDIX domain
NEHDFDCK_00921 3e-303 L HIRAN domain
NEHDFDCK_00922 1.6e-137 S peptidase C26
NEHDFDCK_00923 1.4e-207 cytX U Belongs to the purine-cytosine permease (2.A.39) family
NEHDFDCK_00924 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NEHDFDCK_00925 5e-148 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NEHDFDCK_00926 7.1e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NEHDFDCK_00927 4.2e-178 1.6.5.5 C Zinc-binding dehydrogenase
NEHDFDCK_00928 2.8e-151 larE S NAD synthase
NEHDFDCK_00929 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NEHDFDCK_00930 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
NEHDFDCK_00931 6.9e-131 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NEHDFDCK_00932 2.4e-125 larB S AIR carboxylase
NEHDFDCK_00933 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
NEHDFDCK_00934 4.6e-120 K Crp-like helix-turn-helix domain
NEHDFDCK_00935 1.6e-180 nikMN P PDGLE domain
NEHDFDCK_00936 1.2e-149 P Cobalt transport protein
NEHDFDCK_00937 3.9e-128 cbiO P ABC transporter
NEHDFDCK_00938 4.8e-40
NEHDFDCK_00939 1.4e-139 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
NEHDFDCK_00941 7e-141
NEHDFDCK_00943 8.1e-282 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
NEHDFDCK_00944 6e-76
NEHDFDCK_00945 2.9e-139 S Belongs to the UPF0246 family
NEHDFDCK_00946 2.2e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
NEHDFDCK_00947 1.9e-234 mepA V MATE efflux family protein
NEHDFDCK_00948 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
NEHDFDCK_00949 4.4e-183 1.1.1.1 C nadph quinone reductase
NEHDFDCK_00950 5.7e-126 hchA S DJ-1/PfpI family
NEHDFDCK_00951 1.5e-88 MA20_25245 K FR47-like protein
NEHDFDCK_00952 9.5e-153 EG EamA-like transporter family
NEHDFDCK_00953 3.4e-126 S Protein of unknown function
NEHDFDCK_00954 0.0 tetP J elongation factor G
NEHDFDCK_00955 7.9e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NEHDFDCK_00956 5.5e-172 yobV1 K WYL domain
NEHDFDCK_00957 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
NEHDFDCK_00958 1.9e-80 6.3.3.2 S ASCH
NEHDFDCK_00959 2.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
NEHDFDCK_00960 7.5e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
NEHDFDCK_00961 7.4e-250 yjjP S Putative threonine/serine exporter
NEHDFDCK_00962 6.7e-195 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEHDFDCK_00963 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NEHDFDCK_00964 1.9e-289 QT PucR C-terminal helix-turn-helix domain
NEHDFDCK_00965 1.3e-122 drgA C Nitroreductase family
NEHDFDCK_00966 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
NEHDFDCK_00967 2.3e-164 ptlF S KR domain
NEHDFDCK_00968 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEHDFDCK_00969 1e-72 C FMN binding
NEHDFDCK_00970 2.2e-157 K LysR family
NEHDFDCK_00971 2.2e-249 P Sodium:sulfate symporter transmembrane region
NEHDFDCK_00972 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
NEHDFDCK_00973 2e-115 S Elongation factor G-binding protein, N-terminal
NEHDFDCK_00974 7.6e-64 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
NEHDFDCK_00975 2.2e-119 pnb C nitroreductase
NEHDFDCK_00976 1.1e-91 ung2 3.2.2.27 L Uracil-DNA glycosylase
NEHDFDCK_00977 2.4e-85 S membrane transporter protein
NEHDFDCK_00978 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NEHDFDCK_00979 6.8e-173 htrA 3.4.21.107 O serine protease
NEHDFDCK_00980 8.9e-158 vicX 3.1.26.11 S domain protein
NEHDFDCK_00981 2.9e-151 yycI S YycH protein
NEHDFDCK_00982 1.2e-244 yycH S YycH protein
NEHDFDCK_00983 0.0 vicK 2.7.13.3 T Histidine kinase
NEHDFDCK_00984 6.2e-131 K response regulator
NEHDFDCK_00986 1.7e-37
NEHDFDCK_00987 1.6e-31 cspA K Cold shock protein domain
NEHDFDCK_00988 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
NEHDFDCK_00989 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
NEHDFDCK_00990 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NEHDFDCK_00991 4.5e-143 S haloacid dehalogenase-like hydrolase
NEHDFDCK_00993 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
NEHDFDCK_00994 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NEHDFDCK_00995 1.5e-277 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
NEHDFDCK_00996 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
NEHDFDCK_00997 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NEHDFDCK_00998 4.8e-84 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NEHDFDCK_00999 4e-289 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NEHDFDCK_01000 1.9e-276 E ABC transporter, substratebinding protein
NEHDFDCK_01001 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NEHDFDCK_01002 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEHDFDCK_01003 8.8e-226 yttB EGP Major facilitator Superfamily
NEHDFDCK_01004 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NEHDFDCK_01005 1.4e-67 rplI J Binds to the 23S rRNA
NEHDFDCK_01006 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NEHDFDCK_01007 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NEHDFDCK_01008 6.8e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NEHDFDCK_01009 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
NEHDFDCK_01010 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEHDFDCK_01011 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEHDFDCK_01012 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEHDFDCK_01013 5e-37 yaaA S S4 domain protein YaaA
NEHDFDCK_01014 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEHDFDCK_01015 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEHDFDCK_01016 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NEHDFDCK_01017 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEHDFDCK_01018 5.5e-130 jag S R3H domain protein
NEHDFDCK_01019 5.1e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NEHDFDCK_01020 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NEHDFDCK_01021 6.9e-93 S Cell surface protein
NEHDFDCK_01022 1.2e-159 S Bacterial protein of unknown function (DUF916)
NEHDFDCK_01024 7.3e-302
NEHDFDCK_01025 3.6e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NEHDFDCK_01027 1.4e-253 pepC 3.4.22.40 E aminopeptidase
NEHDFDCK_01028 2.4e-58 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
NEHDFDCK_01029 1.2e-157 degV S DegV family
NEHDFDCK_01030 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
NEHDFDCK_01031 6.7e-142 tesE Q hydratase
NEHDFDCK_01032 1.7e-104 padC Q Phenolic acid decarboxylase
NEHDFDCK_01033 3.1e-98 padR K Virulence activator alpha C-term
NEHDFDCK_01034 2.7e-79 T Universal stress protein family
NEHDFDCK_01035 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NEHDFDCK_01036 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
NEHDFDCK_01037 5.2e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEHDFDCK_01038 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NEHDFDCK_01039 2.7e-160 rbsU U ribose uptake protein RbsU
NEHDFDCK_01040 3.8e-145 IQ NAD dependent epimerase/dehydratase family
NEHDFDCK_01041 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
NEHDFDCK_01042 3.3e-86 gutM K Glucitol operon activator protein (GutM)
NEHDFDCK_01043 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
NEHDFDCK_01044 3.2e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
NEHDFDCK_01045 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NEHDFDCK_01046 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NEHDFDCK_01047 8.7e-72 K Transcriptional regulator
NEHDFDCK_01048 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NEHDFDCK_01049 1.4e-59 T EAL domain
NEHDFDCK_01050 5.6e-161 GM NmrA-like family
NEHDFDCK_01051 6.9e-221 pbuG S Permease family
NEHDFDCK_01052 7.9e-236 pbuX F xanthine permease
NEHDFDCK_01053 1e-298 pucR QT Purine catabolism regulatory protein-like family
NEHDFDCK_01054 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NEHDFDCK_01055 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NEHDFDCK_01056 9.9e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NEHDFDCK_01057 1.2e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NEHDFDCK_01058 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NEHDFDCK_01059 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NEHDFDCK_01060 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NEHDFDCK_01061 6.2e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEHDFDCK_01062 3.5e-169 ydcZ S Putative inner membrane exporter, YdcZ
NEHDFDCK_01063 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NEHDFDCK_01064 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NEHDFDCK_01065 8.2e-96 wecD K Acetyltransferase (GNAT) family
NEHDFDCK_01066 5.6e-115 ylbE GM NAD(P)H-binding
NEHDFDCK_01067 1.9e-161 mleR K LysR family
NEHDFDCK_01068 9.5e-125 S membrane transporter protein
NEHDFDCK_01069 8.7e-18
NEHDFDCK_01070 6.6e-159 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEHDFDCK_01071 2.7e-216 patA 2.6.1.1 E Aminotransferase
NEHDFDCK_01072 7.2e-261 gabR K Bacterial regulatory proteins, gntR family
NEHDFDCK_01073 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NEHDFDCK_01074 8.5e-57 S SdpI/YhfL protein family
NEHDFDCK_01075 1.8e-173 C Zinc-binding dehydrogenase
NEHDFDCK_01076 7.3e-62 K helix_turn_helix, mercury resistance
NEHDFDCK_01077 1.8e-176 yttB EGP Major facilitator Superfamily
NEHDFDCK_01078 1.1e-19 yttB EGP Major facilitator Superfamily
NEHDFDCK_01079 2.9e-269 yjcE P Sodium proton antiporter
NEHDFDCK_01080 4.9e-87 nrdI F Belongs to the NrdI family
NEHDFDCK_01081 1.2e-239 yhdP S Transporter associated domain
NEHDFDCK_01082 4.4e-58
NEHDFDCK_01083 1.6e-73 hspX O Belongs to the small heat shock protein (HSP20) family
NEHDFDCK_01084 2.5e-59
NEHDFDCK_01085 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
NEHDFDCK_01086 5.5e-138 rrp8 K LytTr DNA-binding domain
NEHDFDCK_01087 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHDFDCK_01088 2e-138
NEHDFDCK_01089 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NEHDFDCK_01090 2.4e-130 gntR2 K Transcriptional regulator
NEHDFDCK_01091 1.4e-166 S Putative esterase
NEHDFDCK_01092 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NEHDFDCK_01093 2.7e-224 lsgC M Glycosyl transferases group 1
NEHDFDCK_01094 3.3e-21 S Protein of unknown function (DUF2929)
NEHDFDCK_01095 1.7e-48 K Cro/C1-type HTH DNA-binding domain
NEHDFDCK_01096 1.6e-155 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NEHDFDCK_01097 1.6e-79 uspA T universal stress protein
NEHDFDCK_01098 1.4e-206 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
NEHDFDCK_01099 3.5e-118 yugP S Putative neutral zinc metallopeptidase
NEHDFDCK_01100 4.1e-25
NEHDFDCK_01101 2.5e-145 DegV S EDD domain protein, DegV family
NEHDFDCK_01102 7.3e-127 lrgB M LrgB-like family
NEHDFDCK_01103 5.1e-64 lrgA S LrgA family
NEHDFDCK_01104 3.8e-104 J Acetyltransferase (GNAT) domain
NEHDFDCK_01105 5e-167 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
NEHDFDCK_01106 5.4e-36 S Phospholipase_D-nuclease N-terminal
NEHDFDCK_01107 2.1e-58 S Enterocin A Immunity
NEHDFDCK_01108 9.8e-88 perR P Belongs to the Fur family
NEHDFDCK_01109 2e-106
NEHDFDCK_01110 2.3e-237 S module of peptide synthetase
NEHDFDCK_01111 2e-100 S NADPH-dependent FMN reductase
NEHDFDCK_01112 1.4e-08
NEHDFDCK_01113 2.5e-126 magIII L Base excision DNA repair protein, HhH-GPD family
NEHDFDCK_01114 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
NEHDFDCK_01115 2.6e-155 1.6.5.2 GM NmrA-like family
NEHDFDCK_01116 2e-77 merR K MerR family regulatory protein
NEHDFDCK_01117 2.2e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHDFDCK_01118 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NEHDFDCK_01119 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
NEHDFDCK_01120 2.8e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
NEHDFDCK_01121 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
NEHDFDCK_01122 3.7e-93 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NEHDFDCK_01123 3.6e-146 cof S haloacid dehalogenase-like hydrolase
NEHDFDCK_01124 1.9e-150 qorB 1.6.5.2 GM NmrA-like family
NEHDFDCK_01125 4.4e-163 K LysR substrate binding domain
NEHDFDCK_01126 1.3e-232
NEHDFDCK_01127 6.8e-242 S Neutral/alkaline non-lysosomal ceramidase, N-terminal
NEHDFDCK_01128 0.0 2.7.1.193, 2.7.1.211 G phosphotransferase system
NEHDFDCK_01129 3.9e-206 4.1.1.45 E amidohydrolase
NEHDFDCK_01130 9.4e-77
NEHDFDCK_01131 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEHDFDCK_01132 1.4e-116 ybbL S ABC transporter, ATP-binding protein
NEHDFDCK_01133 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
NEHDFDCK_01134 2.6e-205 S DUF218 domain
NEHDFDCK_01135 3.5e-180 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
NEHDFDCK_01136 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
NEHDFDCK_01137 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
NEHDFDCK_01138 5e-128 S Putative adhesin
NEHDFDCK_01139 5.1e-84 XK27_06920 S Protein of unknown function (DUF1700)
NEHDFDCK_01140 6.8e-53 K Transcriptional regulator
NEHDFDCK_01141 2.9e-78 KT response to antibiotic
NEHDFDCK_01142 3.3e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NEHDFDCK_01143 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NEHDFDCK_01144 8.1e-123 tcyB E ABC transporter
NEHDFDCK_01145 1.8e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NEHDFDCK_01146 5.5e-236 EK Aminotransferase, class I
NEHDFDCK_01147 2.1e-168 K LysR substrate binding domain
NEHDFDCK_01148 1.5e-147 S Alpha/beta hydrolase of unknown function (DUF915)
NEHDFDCK_01150 3.4e-86 rfbP M Bacterial sugar transferase
NEHDFDCK_01151 2.9e-134 ywqE 3.1.3.48 GM PHP domain protein
NEHDFDCK_01152 1.4e-125 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NEHDFDCK_01153 5.4e-111 epsB M biosynthesis protein
NEHDFDCK_01154 4.1e-70 L Transposase
NEHDFDCK_01155 1.8e-137 S response to antibiotic
NEHDFDCK_01156 2.6e-101 S response to antibiotic
NEHDFDCK_01157 1.5e-198 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
NEHDFDCK_01158 4e-243 P Sodium:sulfate symporter transmembrane region
NEHDFDCK_01159 1.2e-163 K LysR substrate binding domain
NEHDFDCK_01160 3e-67
NEHDFDCK_01161 4.9e-22
NEHDFDCK_01162 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEHDFDCK_01163 6.8e-192 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEHDFDCK_01164 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NEHDFDCK_01165 3.3e-80
NEHDFDCK_01166 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NEHDFDCK_01167 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEHDFDCK_01168 3.1e-127 yliE T EAL domain
NEHDFDCK_01169 6.2e-218 2.7.7.65 T Diguanylate cyclase, GGDEF domain
NEHDFDCK_01170 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEHDFDCK_01171 2.8e-38 S Cytochrome B5
NEHDFDCK_01172 1e-236
NEHDFDCK_01173 4.8e-131 treR K UTRA
NEHDFDCK_01174 5.7e-160 I alpha/beta hydrolase fold
NEHDFDCK_01175 1.7e-256 npp S type I phosphodiesterase nucleotide pyrophosphatase
NEHDFDCK_01176 2.2e-233 yxiO S Vacuole effluxer Atg22 like
NEHDFDCK_01177 3.7e-249 puuP_1 E Amino acid permease
NEHDFDCK_01178 4.7e-176 pepR1 3.4.11.5 I Releases the N-terminal proline from various substrates
NEHDFDCK_01179 1.9e-172 ropB K Helix-turn-helix XRE-family like proteins
NEHDFDCK_01180 4.4e-209 EGP Major facilitator Superfamily
NEHDFDCK_01181 0.0 uvrA3 L excinuclease ABC
NEHDFDCK_01182 0.0 S Predicted membrane protein (DUF2207)
NEHDFDCK_01183 2.8e-148 3.1.3.102, 3.1.3.104 S hydrolase
NEHDFDCK_01184 7.1e-308 ybiT S ABC transporter, ATP-binding protein
NEHDFDCK_01185 5.3e-223 S CAAX protease self-immunity
NEHDFDCK_01186 4.3e-131 2.7.1.89 M Phosphotransferase enzyme family
NEHDFDCK_01187 5.7e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
NEHDFDCK_01188 3.2e-103 speG J Acetyltransferase (GNAT) domain
NEHDFDCK_01189 6.3e-139 endA F DNA RNA non-specific endonuclease
NEHDFDCK_01190 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
NEHDFDCK_01191 3.4e-109 K Transcriptional regulator (TetR family)
NEHDFDCK_01192 1.7e-260 yhgE V domain protein
NEHDFDCK_01193 2e-07
NEHDFDCK_01195 3.5e-247 EGP Major facilitator Superfamily
NEHDFDCK_01196 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NEHDFDCK_01197 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEHDFDCK_01198 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NEHDFDCK_01199 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEHDFDCK_01200 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NEHDFDCK_01201 6e-252 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEHDFDCK_01202 3.1e-74 yabR J RNA binding
NEHDFDCK_01203 1.1e-63 divIC D Septum formation initiator
NEHDFDCK_01205 2.2e-42 yabO J S4 domain protein
NEHDFDCK_01206 1.6e-288 yabM S Polysaccharide biosynthesis protein
NEHDFDCK_01207 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEHDFDCK_01208 4.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NEHDFDCK_01209 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NEHDFDCK_01210 1.4e-264 S Putative peptidoglycan binding domain
NEHDFDCK_01211 2.1e-114 S (CBS) domain
NEHDFDCK_01212 4.1e-84 S QueT transporter
NEHDFDCK_01213 9.4e-189 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NEHDFDCK_01214 7.9e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine
NEHDFDCK_01215 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
NEHDFDCK_01216 1.5e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NEHDFDCK_01217 3.6e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NEHDFDCK_01218 2.2e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NEHDFDCK_01219 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NEHDFDCK_01220 5e-134 P ATPases associated with a variety of cellular activities
NEHDFDCK_01221 2.9e-129 ssuC2 U Binding-protein-dependent transport system inner membrane component
NEHDFDCK_01222 6.5e-193 P ABC transporter, substratebinding protein
NEHDFDCK_01223 2.1e-299 kup P Transport of potassium into the cell
NEHDFDCK_01224 5.7e-54 kup P Transport of potassium into the cell
NEHDFDCK_01225 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
NEHDFDCK_01226 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEHDFDCK_01227 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NEHDFDCK_01228 1.5e-257 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NEHDFDCK_01229 1.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEHDFDCK_01230 2e-146
NEHDFDCK_01231 2.1e-139 htpX O Belongs to the peptidase M48B family
NEHDFDCK_01232 2.5e-90 lemA S LemA family
NEHDFDCK_01233 9.2e-127 srtA 3.4.22.70 M sortase family
NEHDFDCK_01234 3.2e-214 J translation release factor activity
NEHDFDCK_01235 4.5e-241 cpdA S Calcineurin-like phosphoesterase
NEHDFDCK_01236 4.1e-262 cps4J S Polysaccharide biosynthesis protein
NEHDFDCK_01237 2.4e-173 cps4I M Glycosyltransferase like family 2
NEHDFDCK_01238 1.2e-228
NEHDFDCK_01239 7.5e-178 cps4G M Glycosyltransferase Family 4
NEHDFDCK_01240 9.3e-174 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
NEHDFDCK_01241 1.8e-127 tuaA M Bacterial sugar transferase
NEHDFDCK_01242 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
NEHDFDCK_01243 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
NEHDFDCK_01244 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NEHDFDCK_01245 2.9e-126 epsB M biosynthesis protein
NEHDFDCK_01246 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEHDFDCK_01247 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NEHDFDCK_01248 9.2e-270 glnPH2 P ABC transporter permease
NEHDFDCK_01249 4.3e-22
NEHDFDCK_01250 9.9e-73 S Iron-sulphur cluster biosynthesis
NEHDFDCK_01251 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NEHDFDCK_01252 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
NEHDFDCK_01253 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEHDFDCK_01254 1.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NEHDFDCK_01255 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NEHDFDCK_01256 2.5e-156 S Tetratricopeptide repeat
NEHDFDCK_01257 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEHDFDCK_01258 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEHDFDCK_01259 3.7e-192 mdtG EGP Major Facilitator Superfamily
NEHDFDCK_01260 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NEHDFDCK_01261 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
NEHDFDCK_01262 1.1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
NEHDFDCK_01263 0.0 comEC S Competence protein ComEC
NEHDFDCK_01264 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
NEHDFDCK_01265 8.2e-120 comEA L Competence protein ComEA
NEHDFDCK_01266 2.4e-195 ylbL T Belongs to the peptidase S16 family
NEHDFDCK_01267 1.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEHDFDCK_01268 1.2e-100 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NEHDFDCK_01269 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NEHDFDCK_01270 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NEHDFDCK_01271 1.6e-205 ftsW D Belongs to the SEDS family
NEHDFDCK_01272 3.2e-37
NEHDFDCK_01273 5.4e-213
NEHDFDCK_01274 5.1e-259 ica2 GT2 M Glycosyl transferase family group 2
NEHDFDCK_01275 1.2e-103
NEHDFDCK_01276 2.3e-100
NEHDFDCK_01282 5.1e-08
NEHDFDCK_01288 2.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
NEHDFDCK_01289 2.9e-59 P secondary active sulfate transmembrane transporter activity
NEHDFDCK_01290 5.1e-102 P secondary active sulfate transmembrane transporter activity
NEHDFDCK_01291 7.6e-94
NEHDFDCK_01292 2e-94 K Acetyltransferase (GNAT) domain
NEHDFDCK_01293 2.9e-156 T Calcineurin-like phosphoesterase superfamily domain
NEHDFDCK_01294 5e-114 rhaS6 K helix_turn_helix, arabinose operon control protein
NEHDFDCK_01295 1.9e-145 I Carboxylesterase family
NEHDFDCK_01296 4.3e-156 yhjX P Major Facilitator Superfamily
NEHDFDCK_01297 7.3e-113 bglK_1 GK ROK family
NEHDFDCK_01298 3.4e-231 mntH P H( )-stimulated, divalent metal cation uptake system
NEHDFDCK_01299 4.4e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NEHDFDCK_01300 5.4e-256 mmuP E amino acid
NEHDFDCK_01301 2.2e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NEHDFDCK_01302 8.7e-292 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
NEHDFDCK_01303 1.6e-121
NEHDFDCK_01304 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEHDFDCK_01305 1.4e-278 bmr3 EGP Major facilitator Superfamily
NEHDFDCK_01306 5.8e-138 N Cell shape-determining protein MreB
NEHDFDCK_01307 0.0 S Pfam Methyltransferase
NEHDFDCK_01308 2.6e-267 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
NEHDFDCK_01309 1.8e-297 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
NEHDFDCK_01310 4.2e-29
NEHDFDCK_01311 1.2e-94 ytqB 2.1.1.176 J Putative rRNA methylase
NEHDFDCK_01312 3e-124 3.6.1.27 I Acid phosphatase homologues
NEHDFDCK_01313 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NEHDFDCK_01314 4.3e-300 ytgP S Polysaccharide biosynthesis protein
NEHDFDCK_01315 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NEHDFDCK_01316 6.4e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEHDFDCK_01317 1.7e-273 pepV 3.5.1.18 E dipeptidase PepV
NEHDFDCK_01318 4.1e-84 uspA T Belongs to the universal stress protein A family
NEHDFDCK_01319 1.8e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
NEHDFDCK_01320 6.4e-171 ugpA U Binding-protein-dependent transport system inner membrane component
NEHDFDCK_01321 3.6e-36 L Integrase
NEHDFDCK_01322 1e-63 K Winged helix DNA-binding domain
NEHDFDCK_01323 1.8e-181 oppF P Belongs to the ABC transporter superfamily
NEHDFDCK_01324 9.2e-203 oppD P Belongs to the ABC transporter superfamily
NEHDFDCK_01325 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEHDFDCK_01326 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEHDFDCK_01327 1.3e-309 oppA E ABC transporter, substratebinding protein
NEHDFDCK_01328 3.2e-57 ywjH S Protein of unknown function (DUF1634)
NEHDFDCK_01329 5.5e-126 yxaA S membrane transporter protein
NEHDFDCK_01330 7.1e-161 lysR5 K LysR substrate binding domain
NEHDFDCK_01331 8.5e-198 M MucBP domain
NEHDFDCK_01332 1.7e-142
NEHDFDCK_01333 7.3e-121
NEHDFDCK_01334 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NEHDFDCK_01335 3.4e-255 gor 1.8.1.7 C Glutathione reductase
NEHDFDCK_01336 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
NEHDFDCK_01337 4.6e-293 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NEHDFDCK_01338 9.5e-213 gntP EG Gluconate
NEHDFDCK_01339 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
NEHDFDCK_01340 2.1e-187 yueF S AI-2E family transporter
NEHDFDCK_01341 8.3e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NEHDFDCK_01342 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
NEHDFDCK_01343 1e-47 K sequence-specific DNA binding
NEHDFDCK_01344 1.3e-134 cwlO M NlpC/P60 family
NEHDFDCK_01345 4.1e-106 ygaC J Belongs to the UPF0374 family
NEHDFDCK_01346 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
NEHDFDCK_01347 3.9e-125
NEHDFDCK_01348 4.4e-100 K DNA-templated transcription, initiation
NEHDFDCK_01349 2.8e-25
NEHDFDCK_01350 7e-30
NEHDFDCK_01351 7.3e-33 S Protein of unknown function (DUF2922)
NEHDFDCK_01352 1.1e-52
NEHDFDCK_01353 2.1e-120 rfbP M Bacterial sugar transferase
NEHDFDCK_01354 2.5e-240 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NEHDFDCK_01355 6.2e-148 cps1D M Domain of unknown function (DUF4422)
NEHDFDCK_01356 9.6e-200 cps3I G Acyltransferase family
NEHDFDCK_01357 8.5e-193 cps3H
NEHDFDCK_01358 1.3e-163 cps3F
NEHDFDCK_01359 1.3e-108 cps3E
NEHDFDCK_01360 5.8e-205 cps3D
NEHDFDCK_01361 1.1e-222 glf 5.4.99.9 M UDP-galactopyranose mutase
NEHDFDCK_01362 5.2e-178 cps3B S Glycosyltransferase like family 2
NEHDFDCK_01363 2.2e-133 cps3A S Glycosyltransferase like family 2
NEHDFDCK_01364 3.4e-35 S Uncharacterized protein conserved in bacteria (DUF2247)
NEHDFDCK_01365 1.2e-41 S SMI1-KNR4 cell-wall
NEHDFDCK_01367 2.8e-48 XK27_04080 H RibD C-terminal domain
NEHDFDCK_01368 4.4e-79 K transcriptional regulator, MerR family
NEHDFDCK_01369 1.8e-74 yphH S Cupin domain
NEHDFDCK_01370 2.5e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
NEHDFDCK_01371 1.4e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHDFDCK_01372 1.4e-210 natB CP ABC-2 family transporter protein
NEHDFDCK_01373 1.2e-166 natA S ABC transporter, ATP-binding protein
NEHDFDCK_01375 8.9e-92 ogt 2.1.1.63 L Methyltransferase
NEHDFDCK_01376 8.6e-52 lytE M LysM domain
NEHDFDCK_01378 4.9e-266 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
NEHDFDCK_01379 1.7e-295 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
NEHDFDCK_01380 4.1e-150 rlrG K Transcriptional regulator
NEHDFDCK_01381 2.1e-172 S Conserved hypothetical protein 698
NEHDFDCK_01382 1.9e-98 rimL J Acetyltransferase (GNAT) domain
NEHDFDCK_01383 1.4e-76 S Domain of unknown function (DUF4811)
NEHDFDCK_01384 1.1e-270 lmrB EGP Major facilitator Superfamily
NEHDFDCK_01385 2.2e-189 ynfM EGP Major facilitator Superfamily
NEHDFDCK_01386 3.4e-258 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
NEHDFDCK_01387 3.6e-155 mleP3 S Membrane transport protein
NEHDFDCK_01388 9.8e-110 S Membrane
NEHDFDCK_01389 1.8e-188 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEHDFDCK_01390 3.1e-98 1.5.1.3 H RibD C-terminal domain
NEHDFDCK_01391 1.7e-187 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NEHDFDCK_01392 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
NEHDFDCK_01393 1.8e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NEHDFDCK_01394 1.1e-174 hrtB V ABC transporter permease
NEHDFDCK_01395 6.6e-95 S Protein of unknown function (DUF1440)
NEHDFDCK_01396 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEHDFDCK_01397 6.4e-148 KT helix_turn_helix, mercury resistance
NEHDFDCK_01398 6.6e-114 S Protein of unknown function (DUF554)
NEHDFDCK_01399 1.1e-92 yueI S Protein of unknown function (DUF1694)
NEHDFDCK_01400 7.7e-143 yvpB S Peptidase_C39 like family
NEHDFDCK_01401 1.9e-149 M Glycosyl hydrolases family 25
NEHDFDCK_01402 3.9e-111
NEHDFDCK_01403 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEHDFDCK_01404 1.8e-84 hmpT S Pfam:DUF3816
NEHDFDCK_01405 1.8e-57 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHDFDCK_01406 1.1e-50 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHDFDCK_01407 1.1e-40 ulaB_1 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
NEHDFDCK_01408 2e-220 ulaA 2.7.1.194 S PTS system sugar-specific permease component
NEHDFDCK_01409 7.4e-99 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
NEHDFDCK_01410 8.7e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NEHDFDCK_01411 2.4e-53 yaaQ S Cyclic-di-AMP receptor
NEHDFDCK_01412 3.3e-186 holB 2.7.7.7 L DNA polymerase III
NEHDFDCK_01413 1e-57 yabA L Involved in initiation control of chromosome replication
NEHDFDCK_01414 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NEHDFDCK_01415 3.6e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
NEHDFDCK_01416 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NEHDFDCK_01417 1.5e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
NEHDFDCK_01418 8.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
NEHDFDCK_01419 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
NEHDFDCK_01420 7.7e-138 phnE 3.6.1.63 U Phosphonate ABC transporter permease
NEHDFDCK_01421 6.3e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NEHDFDCK_01422 5.1e-190 phnD P Phosphonate ABC transporter
NEHDFDCK_01423 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NEHDFDCK_01424 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NEHDFDCK_01425 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NEHDFDCK_01426 5.8e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEHDFDCK_01427 2.8e-306 uup S ABC transporter, ATP-binding protein
NEHDFDCK_01428 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NEHDFDCK_01429 6.1e-109 ydiL S CAAX protease self-immunity
NEHDFDCK_01430 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEHDFDCK_01431 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEHDFDCK_01432 0.0 ydaO E amino acid
NEHDFDCK_01433 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
NEHDFDCK_01434 4.3e-145 pstS P Phosphate
NEHDFDCK_01435 1.7e-114 yvyE 3.4.13.9 S YigZ family
NEHDFDCK_01436 1.1e-256 comFA L Helicase C-terminal domain protein
NEHDFDCK_01437 7.5e-126 comFC S Competence protein
NEHDFDCK_01438 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NEHDFDCK_01439 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEHDFDCK_01440 3.2e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEHDFDCK_01441 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
NEHDFDCK_01442 1.5e-132 K response regulator
NEHDFDCK_01443 3.5e-250 phoR 2.7.13.3 T Histidine kinase
NEHDFDCK_01445 8.6e-249 EGP Major facilitator Superfamily
NEHDFDCK_01446 2.8e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
NEHDFDCK_01447 4.7e-83 cvpA S Colicin V production protein
NEHDFDCK_01448 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NEHDFDCK_01449 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NEHDFDCK_01450 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
NEHDFDCK_01451 4.5e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NEHDFDCK_01452 7.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NEHDFDCK_01453 3.4e-211 folP 2.5.1.15 H dihydropteroate synthase
NEHDFDCK_01454 6.5e-96 tag 3.2.2.20 L glycosylase
NEHDFDCK_01455 2.1e-21
NEHDFDCK_01457 4.3e-101 K Helix-turn-helix XRE-family like proteins
NEHDFDCK_01458 2.7e-160 czcD P cation diffusion facilitator family transporter
NEHDFDCK_01459 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
NEHDFDCK_01460 3e-116 hly S protein, hemolysin III
NEHDFDCK_01461 1.1e-44 qacH U Small Multidrug Resistance protein
NEHDFDCK_01462 4.4e-59 qacC P Small Multidrug Resistance protein
NEHDFDCK_01463 1.2e-216 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
NEHDFDCK_01464 6.9e-179 K AI-2E family transporter
NEHDFDCK_01465 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEHDFDCK_01466 0.0 kup P Transport of potassium into the cell
NEHDFDCK_01468 6.6e-257 yhdG E C-terminus of AA_permease
NEHDFDCK_01469 4.3e-83
NEHDFDCK_01471 8.1e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEHDFDCK_01472 5.8e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
NEHDFDCK_01473 3.5e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEHDFDCK_01474 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NEHDFDCK_01475 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NEHDFDCK_01476 3.4e-55 S Enterocin A Immunity
NEHDFDCK_01477 3.1e-256 gor 1.8.1.7 C Glutathione reductase
NEHDFDCK_01478 4.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NEHDFDCK_01479 1.7e-184 D Alpha beta
NEHDFDCK_01480 7.4e-166 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
NEHDFDCK_01481 3.9e-30 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
NEHDFDCK_01482 2.4e-86 L Integrase core domain
NEHDFDCK_01484 9.6e-112 G transporter
NEHDFDCK_01485 1.2e-226 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NEHDFDCK_01486 2.1e-58 K transcriptional regulator (AraC family)
NEHDFDCK_01487 7.5e-122 1.1.1.1 C nadph quinone reductase
NEHDFDCK_01488 5.8e-60 K Bacterial regulatory proteins, tetR family
NEHDFDCK_01489 5.3e-86
NEHDFDCK_01490 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
NEHDFDCK_01491 1.4e-50
NEHDFDCK_01492 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NEHDFDCK_01493 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NEHDFDCK_01494 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NEHDFDCK_01495 2.6e-39 ylqC S Belongs to the UPF0109 family
NEHDFDCK_01496 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NEHDFDCK_01497 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEHDFDCK_01498 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NEHDFDCK_01499 6.6e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NEHDFDCK_01500 0.0 smc D Required for chromosome condensation and partitioning
NEHDFDCK_01501 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEHDFDCK_01502 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEHDFDCK_01503 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NEHDFDCK_01504 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NEHDFDCK_01505 0.0 yloV S DAK2 domain fusion protein YloV
NEHDFDCK_01506 1.8e-57 asp S Asp23 family, cell envelope-related function
NEHDFDCK_01507 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NEHDFDCK_01508 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
NEHDFDCK_01509 2.8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NEHDFDCK_01510 3.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEHDFDCK_01511 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NEHDFDCK_01512 1.7e-134 stp 3.1.3.16 T phosphatase
NEHDFDCK_01513 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NEHDFDCK_01514 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NEHDFDCK_01515 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEHDFDCK_01516 4e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NEHDFDCK_01517 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NEHDFDCK_01518 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NEHDFDCK_01519 4.5e-55
NEHDFDCK_01520 1.4e-105 opuCD P Binding-protein-dependent transport system inner membrane component
NEHDFDCK_01521 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NEHDFDCK_01522 1.2e-104 opuCB E ABC transporter permease
NEHDFDCK_01523 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
NEHDFDCK_01524 9.7e-308 recN L May be involved in recombinational repair of damaged DNA
NEHDFDCK_01525 7.4e-77 argR K Regulates arginine biosynthesis genes
NEHDFDCK_01526 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NEHDFDCK_01527 5.5e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NEHDFDCK_01528 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEHDFDCK_01529 9.3e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEHDFDCK_01530 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEHDFDCK_01531 5.8e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NEHDFDCK_01532 3.5e-74 yqhY S Asp23 family, cell envelope-related function
NEHDFDCK_01533 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEHDFDCK_01534 5.9e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NEHDFDCK_01535 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NEHDFDCK_01536 3.2e-53 ysxB J Cysteine protease Prp
NEHDFDCK_01537 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NEHDFDCK_01538 2.3e-89 K Transcriptional regulator
NEHDFDCK_01539 5.4e-19
NEHDFDCK_01542 1.7e-30
NEHDFDCK_01543 5.3e-56
NEHDFDCK_01544 3.1e-98 dut S Protein conserved in bacteria
NEHDFDCK_01545 4e-181
NEHDFDCK_01546 2.5e-161
NEHDFDCK_01547 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
NEHDFDCK_01548 4.6e-64 glnR K Transcriptional regulator
NEHDFDCK_01549 2.4e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEHDFDCK_01550 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
NEHDFDCK_01551 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
NEHDFDCK_01552 1.7e-67 yqhL P Rhodanese-like protein
NEHDFDCK_01553 2.4e-110 pepE 3.4.13.21 E Belongs to the peptidase S51 family
NEHDFDCK_01554 5.7e-180 glk 2.7.1.2 G Glucokinase
NEHDFDCK_01555 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
NEHDFDCK_01556 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
NEHDFDCK_01557 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NEHDFDCK_01558 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NEHDFDCK_01559 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NEHDFDCK_01560 0.0 S membrane
NEHDFDCK_01561 1.5e-54 yneR S Belongs to the HesB IscA family
NEHDFDCK_01562 4e-75 XK27_02470 K LytTr DNA-binding domain
NEHDFDCK_01563 2.8e-94 liaI S membrane
NEHDFDCK_01564 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEHDFDCK_01565 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
NEHDFDCK_01566 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NEHDFDCK_01567 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEHDFDCK_01568 1.4e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEHDFDCK_01569 7.4e-64 yodB K Transcriptional regulator, HxlR family
NEHDFDCK_01570 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHDFDCK_01571 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEHDFDCK_01572 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NEHDFDCK_01573 2e-161 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEHDFDCK_01574 1.9e-93 S SdpI/YhfL protein family
NEHDFDCK_01575 1.3e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NEHDFDCK_01576 0.0 sbcC L Putative exonuclease SbcCD, C subunit
NEHDFDCK_01577 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NEHDFDCK_01578 8e-307 arlS 2.7.13.3 T Histidine kinase
NEHDFDCK_01579 4.3e-121 K response regulator
NEHDFDCK_01580 4.2e-245 rarA L recombination factor protein RarA
NEHDFDCK_01581 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEHDFDCK_01582 2.9e-171 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEHDFDCK_01583 2.2e-89 S Peptidase propeptide and YPEB domain
NEHDFDCK_01584 1e-96 yceD S Uncharacterized ACR, COG1399
NEHDFDCK_01585 2.4e-217 ylbM S Belongs to the UPF0348 family
NEHDFDCK_01586 4.4e-140 yqeM Q Methyltransferase
NEHDFDCK_01587 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEHDFDCK_01588 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NEHDFDCK_01589 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEHDFDCK_01590 1.1e-50 yhbY J RNA-binding protein
NEHDFDCK_01591 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
NEHDFDCK_01592 1.4e-98 yqeG S HAD phosphatase, family IIIA
NEHDFDCK_01593 1.3e-79
NEHDFDCK_01594 2.7e-249 pgaC GT2 M Glycosyl transferase
NEHDFDCK_01595 1.5e-135 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
NEHDFDCK_01596 3e-62 hxlR K Transcriptional regulator, HxlR family
NEHDFDCK_01597 1.2e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NEHDFDCK_01598 1.4e-239 yrvN L AAA C-terminal domain
NEHDFDCK_01599 9.9e-57
NEHDFDCK_01600 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEHDFDCK_01601 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NEHDFDCK_01602 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEHDFDCK_01603 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEHDFDCK_01604 3.3e-172 dnaI L Primosomal protein DnaI
NEHDFDCK_01605 2.2e-249 dnaB L replication initiation and membrane attachment
NEHDFDCK_01606 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NEHDFDCK_01607 2.7e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NEHDFDCK_01608 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NEHDFDCK_01609 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEHDFDCK_01610 2.2e-120 ybhL S Belongs to the BI1 family
NEHDFDCK_01611 4.9e-28 yozG K Transcriptional regulator
NEHDFDCK_01612 2.8e-97 S Protein of unknown function (DUF2975)
NEHDFDCK_01613 3.4e-73
NEHDFDCK_01614 2.7e-177
NEHDFDCK_01615 2.1e-123 narI 1.7.5.1 C Nitrate reductase
NEHDFDCK_01616 2.1e-97 narJ C Nitrate reductase delta subunit
NEHDFDCK_01617 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
NEHDFDCK_01618 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NEHDFDCK_01619 2.6e-194 moeB 2.7.7.73, 2.7.7.80 H ThiF family
NEHDFDCK_01620 3.2e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NEHDFDCK_01621 8.2e-232 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
NEHDFDCK_01622 1.8e-89 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NEHDFDCK_01623 1.2e-83 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NEHDFDCK_01624 2.9e-99 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NEHDFDCK_01625 7.8e-39
NEHDFDCK_01626 1.3e-75 ptsP 2.7.13.3, 2.7.3.9 T phosphoenolpyruvate-protein phosphotransferase activity
NEHDFDCK_01627 3.5e-191 comP 2.7.13.3 F Sensor histidine kinase
NEHDFDCK_01628 6.1e-117 nreC K PFAM regulatory protein LuxR
NEHDFDCK_01629 1.5e-49
NEHDFDCK_01630 4.8e-182
NEHDFDCK_01631 2.3e-159 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
NEHDFDCK_01632 6.2e-157 hipB K Helix-turn-helix
NEHDFDCK_01633 8.8e-59 yitW S Iron-sulfur cluster assembly protein
NEHDFDCK_01634 2.5e-217 narK P Transporter, major facilitator family protein
NEHDFDCK_01635 4.5e-196 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NEHDFDCK_01636 5.4e-34 moaD 2.8.1.12 H ThiS family
NEHDFDCK_01637 4.5e-70 moaE 2.8.1.12 H MoaE protein
NEHDFDCK_01638 5.8e-82 fld C NrdI Flavodoxin like
NEHDFDCK_01639 2.2e-166 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHDFDCK_01640 9.7e-138 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
NEHDFDCK_01641 8.4e-172 fecB P Periplasmic binding protein
NEHDFDCK_01642 4.2e-272 sufB O assembly protein SufB
NEHDFDCK_01643 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
NEHDFDCK_01644 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NEHDFDCK_01645 2.6e-244 sufD O FeS assembly protein SufD
NEHDFDCK_01646 4.2e-144 sufC O FeS assembly ATPase SufC
NEHDFDCK_01647 1.3e-34 feoA P FeoA domain
NEHDFDCK_01648 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NEHDFDCK_01649 1.3e-20 S Virus attachment protein p12 family
NEHDFDCK_01650 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NEHDFDCK_01651 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NEHDFDCK_01652 5.3e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEHDFDCK_01653 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
NEHDFDCK_01654 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NEHDFDCK_01655 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
NEHDFDCK_01656 2.4e-223 ecsB U ABC transporter
NEHDFDCK_01657 1.6e-134 ecsA V ABC transporter, ATP-binding protein
NEHDFDCK_01658 9.9e-82 hit FG histidine triad
NEHDFDCK_01659 2e-42
NEHDFDCK_01660 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NEHDFDCK_01661 3.5e-78 S WxL domain surface cell wall-binding
NEHDFDCK_01662 5.2e-103 S WxL domain surface cell wall-binding
NEHDFDCK_01663 1.4e-192 S Fn3-like domain
NEHDFDCK_01664 2.7e-61
NEHDFDCK_01665 0.0
NEHDFDCK_01666 1.8e-240 npr 1.11.1.1 C NADH oxidase
NEHDFDCK_01667 2.8e-111 K Bacterial regulatory proteins, tetR family
NEHDFDCK_01668 1.9e-115 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NEHDFDCK_01669 7.2e-106
NEHDFDCK_01670 3.5e-105 GBS0088 S Nucleotidyltransferase
NEHDFDCK_01671 1.8e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NEHDFDCK_01672 2e-222 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NEHDFDCK_01673 1.8e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NEHDFDCK_01674 6.4e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NEHDFDCK_01675 0.0 S membrane
NEHDFDCK_01676 1.7e-19 S NUDIX domain
NEHDFDCK_01677 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEHDFDCK_01678 4e-184 ykoT GT2 M Glycosyl transferase family 2
NEHDFDCK_01679 1.6e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
NEHDFDCK_01680 1.7e-99
NEHDFDCK_01681 0.0 1.3.5.4 C FAD binding domain
NEHDFDCK_01682 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
NEHDFDCK_01683 1.2e-177 K LysR substrate binding domain
NEHDFDCK_01684 3.6e-182 3.4.21.102 M Peptidase family S41
NEHDFDCK_01685 8.7e-215
NEHDFDCK_01686 3.2e-186 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHDFDCK_01687 0.0 L AAA domain
NEHDFDCK_01688 4.8e-232 yhaO L Ser Thr phosphatase family protein
NEHDFDCK_01689 1e-54 yheA S Belongs to the UPF0342 family
NEHDFDCK_01690 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NEHDFDCK_01691 2.9e-12
NEHDFDCK_01692 4.4e-77 argR K Regulates arginine biosynthesis genes
NEHDFDCK_01693 3.2e-214 arcT 2.6.1.1 E Aminotransferase
NEHDFDCK_01694 9.8e-101 argO S LysE type translocator
NEHDFDCK_01695 8.4e-284 ydfD K Alanine-glyoxylate amino-transferase
NEHDFDCK_01696 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHDFDCK_01697 2e-114 M ErfK YbiS YcfS YnhG
NEHDFDCK_01698 8.1e-157 EGP Major facilitator Superfamily
NEHDFDCK_01699 3.3e-38 EGP Major facilitator Superfamily
NEHDFDCK_01700 2.9e-106
NEHDFDCK_01701 0.0 yhcA V MacB-like periplasmic core domain
NEHDFDCK_01702 2.7e-82
NEHDFDCK_01703 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NEHDFDCK_01704 2.9e-78 elaA S Acetyltransferase (GNAT) domain
NEHDFDCK_01707 1.9e-31
NEHDFDCK_01708 2.1e-244 dinF V MatE
NEHDFDCK_01709 0.0 yfbS P Sodium:sulfate symporter transmembrane region
NEHDFDCK_01710 7.9e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
NEHDFDCK_01711 8.5e-176 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
NEHDFDCK_01712 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
NEHDFDCK_01713 1.6e-229 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
NEHDFDCK_01714 4.8e-304 S Protein conserved in bacteria
NEHDFDCK_01715 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NEHDFDCK_01716 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NEHDFDCK_01717 3.6e-58 S Protein of unknown function (DUF1516)
NEHDFDCK_01718 1.9e-89 gtcA S Teichoic acid glycosylation protein
NEHDFDCK_01719 6.1e-180
NEHDFDCK_01720 3.5e-10
NEHDFDCK_01721 3.6e-57
NEHDFDCK_01724 0.0 uvrA2 L ABC transporter
NEHDFDCK_01725 2.5e-46
NEHDFDCK_01726 1e-90
NEHDFDCK_01727 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
NEHDFDCK_01728 1.5e-113 S CAAX protease self-immunity
NEHDFDCK_01729 2.5e-59
NEHDFDCK_01730 4.5e-55
NEHDFDCK_01731 1.6e-137 pltR K LytTr DNA-binding domain
NEHDFDCK_01732 3.2e-223 pltK 2.7.13.3 T GHKL domain
NEHDFDCK_01733 1.7e-108
NEHDFDCK_01734 2.9e-148 S Sucrose-6F-phosphate phosphohydrolase
NEHDFDCK_01735 4.6e-158 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NEHDFDCK_01736 3.9e-116 GM NAD(P)H-binding
NEHDFDCK_01737 1.6e-64 K helix_turn_helix, mercury resistance
NEHDFDCK_01738 4.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEHDFDCK_01739 2e-175 K LytTr DNA-binding domain
NEHDFDCK_01740 8e-157 V ABC transporter
NEHDFDCK_01741 2.5e-127 V Transport permease protein
NEHDFDCK_01743 2.3e-179 XK27_06930 V domain protein
NEHDFDCK_01744 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NEHDFDCK_01745 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
NEHDFDCK_01746 3.8e-125 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NEHDFDCK_01747 1.2e-260 ugpB G Bacterial extracellular solute-binding protein
NEHDFDCK_01748 1.3e-90 ugpE G ABC transporter permease
NEHDFDCK_01749 2.9e-39 ugpE G ABC transporter permease
NEHDFDCK_01750 1.9e-191 rafA 3.2.1.22 G alpha-galactosidase
NEHDFDCK_01751 2.9e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NEHDFDCK_01752 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NEHDFDCK_01753 9.3e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NEHDFDCK_01754 3.1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NEHDFDCK_01755 1.3e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NEHDFDCK_01756 2e-183 galR K Transcriptional regulator
NEHDFDCK_01757 1.6e-76 K Helix-turn-helix XRE-family like proteins
NEHDFDCK_01758 9.2e-102 fic D Fic/DOC family
NEHDFDCK_01759 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
NEHDFDCK_01760 8.6e-232 EGP Major facilitator Superfamily
NEHDFDCK_01761 5.2e-303 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NEHDFDCK_01762 7.3e-231 mdtH P Sugar (and other) transporter
NEHDFDCK_01763 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NEHDFDCK_01764 1.6e-188 lacR K Transcriptional regulator
NEHDFDCK_01765 0.0 lacA 3.2.1.23 G -beta-galactosidase
NEHDFDCK_01766 0.0 lacS G Transporter
NEHDFDCK_01767 2.9e-249 brnQ U Component of the transport system for branched-chain amino acids
NEHDFDCK_01768 0.0 ubiB S ABC1 family
NEHDFDCK_01769 6.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
NEHDFDCK_01770 2.4e-220 3.1.3.1 S associated with various cellular activities
NEHDFDCK_01771 6.9e-248 S Putative metallopeptidase domain
NEHDFDCK_01772 1.5e-49
NEHDFDCK_01773 5.4e-104 K Bacterial regulatory proteins, tetR family
NEHDFDCK_01774 0.0 mdlA V ABC transporter
NEHDFDCK_01775 0.0 mdlB V ABC transporter
NEHDFDCK_01777 1.1e-192 C Aldo/keto reductase family
NEHDFDCK_01778 8.2e-101 M Protein of unknown function (DUF3737)
NEHDFDCK_01779 2.5e-222 patB 4.4.1.8 E Aminotransferase, class I
NEHDFDCK_01780 1.1e-101 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
NEHDFDCK_01781 1.5e-81
NEHDFDCK_01782 9.9e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NEHDFDCK_01783 5.8e-95 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
NEHDFDCK_01784 6.1e-76 T Belongs to the universal stress protein A family
NEHDFDCK_01785 1.3e-34
NEHDFDCK_01786 2.1e-149 IQ Enoyl-(Acyl carrier protein) reductase
NEHDFDCK_01787 2.3e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NEHDFDCK_01788 1.4e-41 GM NAD(P)H-binding
NEHDFDCK_01789 2.2e-50 GM NAD(P)H-binding
NEHDFDCK_01790 1.9e-158 K LysR substrate binding domain
NEHDFDCK_01791 1.3e-63 S Domain of unknown function (DUF4440)
NEHDFDCK_01792 4.4e-112 pgm8 G Histidine phosphatase superfamily (branch 1)
NEHDFDCK_01793 1.8e-47
NEHDFDCK_01794 7e-37
NEHDFDCK_01795 9.5e-86 yvbK 3.1.3.25 K GNAT family
NEHDFDCK_01796 1.3e-84
NEHDFDCK_01797 1.5e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NEHDFDCK_01798 4.2e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NEHDFDCK_01799 1.4e-99 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NEHDFDCK_01800 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NEHDFDCK_01802 4.9e-120 macB V ABC transporter, ATP-binding protein
NEHDFDCK_01803 1.8e-20 S Short C-terminal domain
NEHDFDCK_01806 2.9e-43 L HTH-like domain
NEHDFDCK_01807 3.4e-36 L transposase activity
NEHDFDCK_01808 3.2e-60 L Belongs to the 'phage' integrase family
NEHDFDCK_01811 1.6e-31
NEHDFDCK_01812 1.9e-141 Q Methyltransferase
NEHDFDCK_01813 8.5e-57 ybjQ S Belongs to the UPF0145 family
NEHDFDCK_01814 2.1e-211 EGP Major facilitator Superfamily
NEHDFDCK_01815 1e-102 K Helix-turn-helix domain
NEHDFDCK_01816 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEHDFDCK_01817 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NEHDFDCK_01818 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
NEHDFDCK_01819 1.1e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHDFDCK_01820 2.8e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NEHDFDCK_01821 1.2e-45
NEHDFDCK_01822 6.9e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEHDFDCK_01823 1.5e-135 fruR K DeoR C terminal sensor domain
NEHDFDCK_01824 5.1e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NEHDFDCK_01825 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
NEHDFDCK_01826 9.6e-11 EGP Major Facilitator Superfamily
NEHDFDCK_01827 4.7e-168 K Transcriptional regulator, LysR family
NEHDFDCK_01828 2.1e-165 G Xylose isomerase-like TIM barrel
NEHDFDCK_01829 1e-156 IQ Enoyl-(Acyl carrier protein) reductase
NEHDFDCK_01830 1.6e-149 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEHDFDCK_01831 1.9e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEHDFDCK_01832 1.2e-219 ydiN EGP Major Facilitator Superfamily
NEHDFDCK_01833 2e-174 K Transcriptional regulator, LysR family
NEHDFDCK_01834 2.8e-165 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEHDFDCK_01835 3.5e-132 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NEHDFDCK_01836 1.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEHDFDCK_01837 0.0 1.3.5.4 C FAD binding domain
NEHDFDCK_01838 2.4e-65 S pyridoxamine 5-phosphate
NEHDFDCK_01839 2.6e-194 C Aldo keto reductase family protein
NEHDFDCK_01840 1.1e-173 galR K Transcriptional regulator
NEHDFDCK_01841 4.1e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NEHDFDCK_01842 0.0 lacS G Transporter
NEHDFDCK_01843 1.4e-234 rafA 3.2.1.22 G alpha-galactosidase
NEHDFDCK_01844 1e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NEHDFDCK_01845 3.1e-206 araR K Transcriptional regulator
NEHDFDCK_01846 1.6e-255 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEHDFDCK_01847 2.5e-305 araB 2.7.1.12, 2.7.1.16, 2.7.1.5 G carbohydrate kinase FGGY
NEHDFDCK_01848 1e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NEHDFDCK_01849 1.3e-265 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NEHDFDCK_01850 6.2e-102 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
NEHDFDCK_01851 2.6e-70 yueI S Protein of unknown function (DUF1694)
NEHDFDCK_01852 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NEHDFDCK_01853 5.2e-123 K DeoR C terminal sensor domain
NEHDFDCK_01854 5.6e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHDFDCK_01855 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
NEHDFDCK_01856 1.1e-231 gatC G PTS system sugar-specific permease component
NEHDFDCK_01857 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
NEHDFDCK_01858 1.3e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
NEHDFDCK_01859 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NEHDFDCK_01860 2.8e-134 S zinc-ribbon domain
NEHDFDCK_01862 1.2e-36
NEHDFDCK_01863 8.2e-134 aroD S Alpha/beta hydrolase family
NEHDFDCK_01864 3.4e-176 S Phosphotransferase system, EIIC
NEHDFDCK_01865 1.7e-268 I acetylesterase activity
NEHDFDCK_01866 7.9e-223 sdrF M Collagen binding domain
NEHDFDCK_01867 4.8e-160 yicL EG EamA-like transporter family
NEHDFDCK_01868 1.1e-127 E lipolytic protein G-D-S-L family
NEHDFDCK_01869 3e-178 4.1.1.52 S Amidohydrolase
NEHDFDCK_01870 2.5e-112 K Transcriptional regulator C-terminal region
NEHDFDCK_01871 7.6e-46 3.6.4.12 K HxlR-like helix-turn-helix
NEHDFDCK_01872 2e-51 V COG1131 ABC-type multidrug transport system, ATPase component
NEHDFDCK_01875 1.4e-22
NEHDFDCK_01876 1.2e-15 yybN S Protein of unknown function (DUF2712)
NEHDFDCK_01877 3.3e-63 K LytTr DNA-binding domain
NEHDFDCK_01878 6.1e-54 2.7.13.3 T GHKL domain
NEHDFDCK_01881 3.8e-57 L Integrase
NEHDFDCK_01882 0.0 clpE O Belongs to the ClpA ClpB family
NEHDFDCK_01883 6.5e-30
NEHDFDCK_01884 2.7e-39 ptsH G phosphocarrier protein HPR
NEHDFDCK_01885 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEHDFDCK_01886 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NEHDFDCK_01887 4.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
NEHDFDCK_01888 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEHDFDCK_01889 4.3e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NEHDFDCK_01890 7.7e-227 patA 2.6.1.1 E Aminotransferase
NEHDFDCK_01891 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
NEHDFDCK_01892 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NEHDFDCK_01893 5.7e-19 M domain protein
NEHDFDCK_01894 3.8e-73 M dTDP-4-dehydrorhamnose reductase activity
NEHDFDCK_01895 4.1e-74
NEHDFDCK_01896 1.6e-39
NEHDFDCK_01897 2.4e-38
NEHDFDCK_01898 9.6e-120 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NEHDFDCK_01899 5.3e-196 uhpT EGP Major facilitator Superfamily
NEHDFDCK_01900 3.4e-146 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
NEHDFDCK_01901 4.3e-166 K Transcriptional regulator
NEHDFDCK_01902 1.4e-150 S hydrolase
NEHDFDCK_01903 1.7e-254 brnQ U Component of the transport system for branched-chain amino acids
NEHDFDCK_01904 2.1e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEHDFDCK_01905 6.9e-116
NEHDFDCK_01907 6.9e-17 2.7.13.3 T GHKL domain
NEHDFDCK_01909 6.2e-51 repA S Replication initiator protein A
NEHDFDCK_01910 7.4e-43 relB L Addiction module antitoxin, RelB DinJ family
NEHDFDCK_01911 1.1e-86
NEHDFDCK_01912 1.2e-40
NEHDFDCK_01913 4.2e-27
NEHDFDCK_01914 0.0 L MobA MobL family protein
NEHDFDCK_01915 5.3e-116
NEHDFDCK_01916 5.9e-32
NEHDFDCK_01917 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NEHDFDCK_01918 5.5e-30
NEHDFDCK_01919 4.3e-68 L Psort location Cytoplasmic, score
NEHDFDCK_01920 7.4e-108 L Psort location Cytoplasmic, score
NEHDFDCK_01921 1.5e-169 L Integrase core domain
NEHDFDCK_01922 3e-131 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
NEHDFDCK_01923 7.3e-241 cps2I S Psort location CytoplasmicMembrane, score
NEHDFDCK_01924 2.4e-86 L Integrase core domain
NEHDFDCK_01925 4.3e-86 yhbO 3.5.1.124 S Intracellular protease
NEHDFDCK_01926 7.3e-129 EGP Major facilitator Superfamily
NEHDFDCK_01927 2e-162 yxaB GM Polysaccharide pyruvyl transferase
NEHDFDCK_01928 1.4e-240 iolT EGP Major facilitator Superfamily
NEHDFDCK_01929 5.9e-12
NEHDFDCK_01930 8.9e-11 S Domain of unknown function (DUF4355)
NEHDFDCK_01931 1.5e-56 S Domain of unknown function (DUF4355)
NEHDFDCK_01932 3.2e-15 gpG
NEHDFDCK_01933 6.7e-44 gpG
NEHDFDCK_01934 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NEHDFDCK_01935 2.1e-46 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEHDFDCK_01936 2.7e-124 3.6.3.6 P Cation transporter/ATPase, N-terminus
NEHDFDCK_01937 3.4e-250 3.6.3.6 P Cation transporter/ATPase, N-terminus
NEHDFDCK_01938 4.5e-180 C Zinc-binding dehydrogenase
NEHDFDCK_01939 1.2e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
NEHDFDCK_01940 7.2e-184
NEHDFDCK_01941 1.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
NEHDFDCK_01942 7.8e-61 P Rhodanese Homology Domain
NEHDFDCK_01943 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NEHDFDCK_01944 6.9e-84 K helix_turn_helix multiple antibiotic resistance protein
NEHDFDCK_01945 4.3e-164 drrA V ABC transporter
NEHDFDCK_01946 2e-119 drrB U ABC-2 type transporter
NEHDFDCK_01947 2.1e-219 M O-Antigen ligase
NEHDFDCK_01948 1.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
NEHDFDCK_01949 1.2e-196 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NEHDFDCK_01950 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NEHDFDCK_01951 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEHDFDCK_01952 7.3e-29 S Protein of unknown function (DUF2929)
NEHDFDCK_01953 0.0 dnaE 2.7.7.7 L DNA polymerase
NEHDFDCK_01954 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NEHDFDCK_01955 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NEHDFDCK_01956 1.5e-74 yeaL S Protein of unknown function (DUF441)
NEHDFDCK_01957 2.9e-170 cvfB S S1 domain
NEHDFDCK_01958 1.1e-164 xerD D recombinase XerD
NEHDFDCK_01959 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEHDFDCK_01960 1.4e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NEHDFDCK_01961 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NEHDFDCK_01962 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NEHDFDCK_01963 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NEHDFDCK_01964 2e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
NEHDFDCK_01965 5.8e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NEHDFDCK_01966 2e-19 M Lysin motif
NEHDFDCK_01967 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NEHDFDCK_01968 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
NEHDFDCK_01969 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NEHDFDCK_01970 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NEHDFDCK_01971 2.1e-206 S Tetratricopeptide repeat protein
NEHDFDCK_01972 2e-149 3.1.3.102, 3.1.3.104 S hydrolase
NEHDFDCK_01973 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NEHDFDCK_01974 2.5e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NEHDFDCK_01975 9.6e-85
NEHDFDCK_01976 0.0 yfmR S ABC transporter, ATP-binding protein
NEHDFDCK_01977 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NEHDFDCK_01978 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NEHDFDCK_01979 2e-147 DegV S EDD domain protein, DegV family
NEHDFDCK_01980 2.3e-149 ypmR E GDSL-like Lipase/Acylhydrolase
NEHDFDCK_01981 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NEHDFDCK_01982 3.4e-35 yozE S Belongs to the UPF0346 family
NEHDFDCK_01983 7.8e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NEHDFDCK_01984 3.3e-251 emrY EGP Major facilitator Superfamily
NEHDFDCK_01985 1.5e-197 XK27_00915 C Luciferase-like monooxygenase
NEHDFDCK_01986 1.1e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
NEHDFDCK_01987 2.7e-174 L restriction endonuclease
NEHDFDCK_01988 2.3e-170 cpsY K Transcriptional regulator, LysR family
NEHDFDCK_01989 1.4e-228 XK27_05470 E Methionine synthase
NEHDFDCK_01991 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NEHDFDCK_01992 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEHDFDCK_01993 4.7e-157 dprA LU DNA protecting protein DprA
NEHDFDCK_01994 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEHDFDCK_01995 9.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NEHDFDCK_01996 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
NEHDFDCK_01997 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NEHDFDCK_01998 1.5e-256 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NEHDFDCK_01999 1.1e-169 lacX 5.1.3.3 G Aldose 1-epimerase
NEHDFDCK_02000 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NEHDFDCK_02001 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEHDFDCK_02002 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEHDFDCK_02003 1.2e-177 K Transcriptional regulator
NEHDFDCK_02004 1.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
NEHDFDCK_02005 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NEHDFDCK_02006 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEHDFDCK_02007 4.2e-32 S YozE SAM-like fold
NEHDFDCK_02008 4.6e-157 xerD L Phage integrase, N-terminal SAM-like domain
NEHDFDCK_02009 7.5e-275 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEHDFDCK_02010 9.3e-242 M Glycosyl transferase family group 2
NEHDFDCK_02011 2.1e-51
NEHDFDCK_02012 1.2e-239 gshR1 1.8.1.7 C Glutathione reductase
NEHDFDCK_02013 1.8e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
NEHDFDCK_02014 8.5e-93 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NEHDFDCK_02015 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEHDFDCK_02016 3e-196 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEHDFDCK_02017 1.2e-191 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NEHDFDCK_02018 3.7e-128 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NEHDFDCK_02019 2.6e-226
NEHDFDCK_02020 1.4e-279 lldP C L-lactate permease
NEHDFDCK_02021 4.1e-59
NEHDFDCK_02022 4.1e-116
NEHDFDCK_02023 2.1e-244 cycA E Amino acid permease
NEHDFDCK_02024 6.1e-133 XK27_00890 S Domain of unknown function (DUF368)
NEHDFDCK_02025 4.6e-129 yejC S Protein of unknown function (DUF1003)
NEHDFDCK_02026 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
NEHDFDCK_02027 4.6e-12
NEHDFDCK_02028 8.9e-207 pmrB EGP Major facilitator Superfamily
NEHDFDCK_02029 3.3e-149 2.7.7.12 C Domain of unknown function (DUF4931)
NEHDFDCK_02030 1.4e-49
NEHDFDCK_02031 4.3e-10
NEHDFDCK_02032 1.3e-131 S Protein of unknown function (DUF975)
NEHDFDCK_02033 2.9e-30 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
NEHDFDCK_02034 7.7e-40 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
NEHDFDCK_02035 7e-161 degV S EDD domain protein, DegV family
NEHDFDCK_02036 1.9e-66 K Transcriptional regulator
NEHDFDCK_02037 0.0 FbpA K Fibronectin-binding protein
NEHDFDCK_02038 3.4e-77 S ABC-2 family transporter protein
NEHDFDCK_02039 3.2e-37 S ABC-2 family transporter protein
NEHDFDCK_02040 2.4e-164 V ABC transporter, ATP-binding protein
NEHDFDCK_02041 1.2e-91 3.6.1.55 F NUDIX domain
NEHDFDCK_02043 8.6e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
NEHDFDCK_02044 1.7e-46 S LuxR family transcriptional regulator
NEHDFDCK_02045 1.1e-129 cat 2.3.1.28 V Chloramphenicol acetyltransferase
NEHDFDCK_02047 3.5e-32 frataxin S Domain of unknown function (DU1801)
NEHDFDCK_02048 6.4e-113 pgm5 G Phosphoglycerate mutase family
NEHDFDCK_02049 4e-288 S Bacterial membrane protein, YfhO
NEHDFDCK_02050 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NEHDFDCK_02051 1.1e-206 carA 6.3.5.5 F Belongs to the CarA family
NEHDFDCK_02052 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NEHDFDCK_02053 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NEHDFDCK_02054 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NEHDFDCK_02055 4.1e-295 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NEHDFDCK_02056 3.3e-62 esbA S Family of unknown function (DUF5322)
NEHDFDCK_02057 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
NEHDFDCK_02058 3.2e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
NEHDFDCK_02059 1.5e-146 S hydrolase activity, acting on ester bonds
NEHDFDCK_02060 3.5e-194
NEHDFDCK_02061 6.6e-122 3.6.3.35 P ATPases associated with a variety of cellular activities
NEHDFDCK_02062 9.2e-125
NEHDFDCK_02063 7.3e-39 mccF 3.4.17.13 V LD-carboxypeptidase
NEHDFDCK_02064 9.7e-132 mccF 3.4.17.13 V LD-carboxypeptidase
NEHDFDCK_02065 6.9e-240 M hydrolase, family 25
NEHDFDCK_02066 1.4e-78 K Acetyltransferase (GNAT) domain
NEHDFDCK_02067 1.9e-169 mccF V LD-carboxypeptidase
NEHDFDCK_02068 2.5e-26 mccF V LD-carboxypeptidase
NEHDFDCK_02069 1.8e-243 M Glycosyltransferase, group 2 family protein
NEHDFDCK_02070 4.4e-73 S SnoaL-like domain
NEHDFDCK_02071 1.4e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NEHDFDCK_02072 3e-243 P Major Facilitator Superfamily
NEHDFDCK_02073 3.4e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
NEHDFDCK_02074 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NEHDFDCK_02076 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NEHDFDCK_02077 8.3e-110 ypsA S Belongs to the UPF0398 family
NEHDFDCK_02078 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NEHDFDCK_02079 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NEHDFDCK_02080 1.8e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
NEHDFDCK_02081 1.1e-181 ftpB P Bacterial extracellular solute-binding protein
NEHDFDCK_02082 1.6e-302 ftpA P Binding-protein-dependent transport system inner membrane component
NEHDFDCK_02083 7.6e-83 uspA T Universal stress protein family
NEHDFDCK_02084 2.7e-157 metQ_4 P Belongs to the nlpA lipoprotein family
NEHDFDCK_02085 2e-99 metI P ABC transporter permease
NEHDFDCK_02086 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEHDFDCK_02088 1.3e-128 dnaD L Replication initiation and membrane attachment
NEHDFDCK_02089 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NEHDFDCK_02090 4.3e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NEHDFDCK_02091 2.1e-72 ypmB S protein conserved in bacteria
NEHDFDCK_02092 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NEHDFDCK_02093 3.8e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NEHDFDCK_02094 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NEHDFDCK_02095 7.6e-205 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NEHDFDCK_02096 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NEHDFDCK_02097 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NEHDFDCK_02098 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NEHDFDCK_02099 1.3e-249 malT G Major Facilitator
NEHDFDCK_02100 1.7e-82 S Domain of unknown function (DUF4767)
NEHDFDCK_02101 1.8e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NEHDFDCK_02102 1.2e-149 yitU 3.1.3.104 S hydrolase
NEHDFDCK_02103 1.4e-265 yfnA E Amino Acid
NEHDFDCK_02104 3.7e-257 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NEHDFDCK_02105 2.4e-43
NEHDFDCK_02106 3.9e-50
NEHDFDCK_02107 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
NEHDFDCK_02108 1e-170 2.5.1.74 H UbiA prenyltransferase family
NEHDFDCK_02109 3.7e-254 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEHDFDCK_02110 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NEHDFDCK_02111 8.6e-281 pipD E Dipeptidase
NEHDFDCK_02112 9.4e-40
NEHDFDCK_02113 4.8e-29 S CsbD-like
NEHDFDCK_02114 6.5e-41 S transglycosylase associated protein
NEHDFDCK_02115 3.1e-14
NEHDFDCK_02116 3.5e-36
NEHDFDCK_02117 1.8e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
NEHDFDCK_02118 8e-66 S Protein of unknown function (DUF805)
NEHDFDCK_02119 6.3e-76 uspA T Belongs to the universal stress protein A family
NEHDFDCK_02120 1.9e-67 tspO T TspO/MBR family
NEHDFDCK_02121 7.9e-41
NEHDFDCK_02122 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
NEHDFDCK_02123 1.3e-113 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
NEHDFDCK_02124 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NEHDFDCK_02125 2.9e-20
NEHDFDCK_02126 1.1e-53
NEHDFDCK_02127 8.4e-14 K Bacterial regulatory proteins, tetR family
NEHDFDCK_02128 2.7e-85 S Protein of unknown function with HXXEE motif
NEHDFDCK_02129 1.2e-139 f42a O Band 7 protein
NEHDFDCK_02130 1.2e-300 norB EGP Major Facilitator
NEHDFDCK_02131 6.2e-94 K transcriptional regulator
NEHDFDCK_02132 1.5e-192 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEHDFDCK_02133 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
NEHDFDCK_02134 5.2e-159 K LysR substrate binding domain
NEHDFDCK_02135 2.7e-121 S Protein of unknown function (DUF554)
NEHDFDCK_02136 9.2e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NEHDFDCK_02137 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NEHDFDCK_02138 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NEHDFDCK_02139 4.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NEHDFDCK_02140 1.1e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NEHDFDCK_02141 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NEHDFDCK_02142 6.6e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NEHDFDCK_02143 1.6e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NEHDFDCK_02144 1.2e-126 IQ reductase
NEHDFDCK_02145 2e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NEHDFDCK_02146 1.3e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEHDFDCK_02147 1.1e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEHDFDCK_02148 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NEHDFDCK_02149 3.8e-179 yneE K Transcriptional regulator
NEHDFDCK_02150 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHDFDCK_02151 8.5e-60 S Protein of unknown function (DUF1648)
NEHDFDCK_02152 2.7e-199 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NEHDFDCK_02153 1.3e-215 3.5.1.47 E Peptidase family M20/M25/M40
NEHDFDCK_02154 4.4e-217 E glutamate:sodium symporter activity
NEHDFDCK_02155 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
NEHDFDCK_02156 1.3e-176 1.6.5.5 C Zinc-binding dehydrogenase
NEHDFDCK_02157 2e-97 entB 3.5.1.19 Q Isochorismatase family
NEHDFDCK_02158 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NEHDFDCK_02159 2.1e-227 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEHDFDCK_02160 4.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NEHDFDCK_02161 4.9e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NEHDFDCK_02162 5.9e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NEHDFDCK_02163 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
NEHDFDCK_02164 2e-269 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
NEHDFDCK_02166 2.1e-272 XK27_00765
NEHDFDCK_02167 2.4e-136 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
NEHDFDCK_02168 3.7e-142 EGP Major facilitator Superfamily
NEHDFDCK_02169 3.7e-58 bglK_1 GK ROK family
NEHDFDCK_02170 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
NEHDFDCK_02171 1.8e-12
NEHDFDCK_02172 8.7e-160 2.7.13.3 T GHKL domain
NEHDFDCK_02173 5.7e-135 K LytTr DNA-binding domain
NEHDFDCK_02174 4.9e-78 yneH 1.20.4.1 K ArsC family
NEHDFDCK_02175 4.2e-291 katA 1.11.1.6 C Belongs to the catalase family
NEHDFDCK_02176 9e-13 ytgB S Transglycosylase associated protein
NEHDFDCK_02177 3.6e-11
NEHDFDCK_02178 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
NEHDFDCK_02179 4.2e-70 S Pyrimidine dimer DNA glycosylase
NEHDFDCK_02180 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
NEHDFDCK_02181 1.6e-90 S PAS domain
NEHDFDCK_02182 1.3e-274 macB_3 V FtsX-like permease family
NEHDFDCK_02183 3.7e-176 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NEHDFDCK_02184 7.8e-247 emrY EGP Major facilitator Superfamily
NEHDFDCK_02185 3.2e-45 ywfI S Chlorite dismutase
NEHDFDCK_02186 1.8e-20 S FRG
NEHDFDCK_02187 2.8e-220 EGP Major facilitator Superfamily
NEHDFDCK_02188 2.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHDFDCK_02189 1.3e-14 3.3.1.1 H adenosylhomocysteinase activity
NEHDFDCK_02190 2.8e-88
NEHDFDCK_02191 2.9e-176 L Initiator Replication protein
NEHDFDCK_02192 2.5e-29
NEHDFDCK_02193 2.3e-107 L Integrase
NEHDFDCK_02194 2.4e-40 K prlF antitoxin for toxin YhaV_toxin
NEHDFDCK_02195 5.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NEHDFDCK_02196 0.0 ybfG M peptidoglycan-binding domain-containing protein
NEHDFDCK_02198 1.7e-84 dps P Belongs to the Dps family
NEHDFDCK_02199 8e-42 S RelB antitoxin
NEHDFDCK_02200 1.6e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NEHDFDCK_02204 4.7e-29
NEHDFDCK_02205 1.9e-25 S Protein of unknown function (DUF1093)
NEHDFDCK_02206 1.6e-63 K Helix-turn-helix XRE-family like proteins
NEHDFDCK_02207 1.9e-16
NEHDFDCK_02208 3e-53 L Integrase
NEHDFDCK_02209 5.6e-33
NEHDFDCK_02210 3.3e-24
NEHDFDCK_02211 0.0 traA L MobA MobL family protein
NEHDFDCK_02212 5.3e-146 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NEHDFDCK_02213 1.8e-193 glf 5.4.99.9 M UDP-galactopyranose mutase
NEHDFDCK_02214 8.1e-169 wbbI M transferase activity, transferring glycosyl groups
NEHDFDCK_02215 8.5e-46 L Transposase
NEHDFDCK_02217 5.2e-56 3.1.3.16 S Protein of unknown function (DUF1643)
NEHDFDCK_02218 2.8e-141 L Phage integrase SAM-like domain
NEHDFDCK_02219 3.6e-23 S Mor transcription activator family
NEHDFDCK_02220 3.1e-26
NEHDFDCK_02221 1.2e-77
NEHDFDCK_02223 6e-144 D PHP domain protein
NEHDFDCK_02224 7.6e-29
NEHDFDCK_02226 2.8e-60 L Integrase
NEHDFDCK_02227 1.2e-68
NEHDFDCK_02228 5.9e-26 K Transcriptional
NEHDFDCK_02229 5.8e-32
NEHDFDCK_02230 1.1e-154 L Initiator Replication protein
NEHDFDCK_02231 2.4e-50
NEHDFDCK_02232 7.5e-115 2.7.7.49 L Reverse transcriptase (RNA-dependent DNA polymerase)
NEHDFDCK_02233 7.1e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
NEHDFDCK_02234 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NEHDFDCK_02235 1.9e-57
NEHDFDCK_02236 6e-31 cspA K Cold shock protein
NEHDFDCK_02237 3.8e-40
NEHDFDCK_02238 4.9e-16
NEHDFDCK_02239 2.3e-107 L Integrase
NEHDFDCK_02240 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
NEHDFDCK_02241 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NEHDFDCK_02242 2.5e-94 L Integrase core domain
NEHDFDCK_02243 2.4e-28 ymbI L Transposase and inactivated derivatives
NEHDFDCK_02244 4.7e-114 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
NEHDFDCK_02245 4.4e-149 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEHDFDCK_02246 3.2e-69 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEHDFDCK_02247 1.7e-88 L Helix-turn-helix domain
NEHDFDCK_02248 3.5e-163 L PFAM Integrase catalytic region
NEHDFDCK_02250 7.7e-32 S EpsG family
NEHDFDCK_02251 2.3e-94 L Transposase DDE domain
NEHDFDCK_02252 6.8e-34 L Transposase DDE domain
NEHDFDCK_02253 5.8e-58 S Glycosyltransferase like family 2
NEHDFDCK_02255 1.6e-10 M Glycosyl transferase 4-like
NEHDFDCK_02256 1.9e-217 2.7.7.65 T diguanylate cyclase
NEHDFDCK_02257 5.1e-34
NEHDFDCK_02258 2e-35
NEHDFDCK_02259 8.6e-81 K AsnC family
NEHDFDCK_02260 4.1e-172 ykfC 3.4.14.13 M NlpC/P60 family
NEHDFDCK_02261 5.9e-160 S Alpha/beta hydrolase of unknown function (DUF915)
NEHDFDCK_02263 3.8e-23
NEHDFDCK_02264 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
NEHDFDCK_02265 1.7e-213 yceI EGP Major facilitator Superfamily
NEHDFDCK_02266 8.6e-48
NEHDFDCK_02267 7.7e-92 S ECF-type riboflavin transporter, S component
NEHDFDCK_02269 4.5e-169 EG EamA-like transporter family
NEHDFDCK_02270 2.3e-38 gcvR T Belongs to the UPF0237 family
NEHDFDCK_02271 3e-243 XK27_08635 S UPF0210 protein
NEHDFDCK_02272 3.6e-134 K response regulator
NEHDFDCK_02273 1.1e-286 yclK 2.7.13.3 T Histidine kinase
NEHDFDCK_02274 3.2e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
NEHDFDCK_02275 9.7e-155 glcU U sugar transport
NEHDFDCK_02276 3.9e-259 pgi 5.3.1.9 G Belongs to the GPI family
NEHDFDCK_02277 6.8e-24
NEHDFDCK_02278 0.0 macB3 V ABC transporter, ATP-binding protein
NEHDFDCK_02279 2.9e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NEHDFDCK_02280 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
NEHDFDCK_02281 1.6e-16
NEHDFDCK_02282 1.9e-18
NEHDFDCK_02283 1.6e-16
NEHDFDCK_02284 1.6e-16
NEHDFDCK_02285 1.6e-16
NEHDFDCK_02286 1.1e-18
NEHDFDCK_02287 2.6e-14
NEHDFDCK_02288 7.2e-17
NEHDFDCK_02289 2.7e-16
NEHDFDCK_02290 0.0 M MucBP domain
NEHDFDCK_02291 0.0 bztC D nuclear chromosome segregation
NEHDFDCK_02292 7.3e-83 K MarR family
NEHDFDCK_02293 7.1e-43
NEHDFDCK_02294 2e-38
NEHDFDCK_02295 1.9e-225 sip L Belongs to the 'phage' integrase family
NEHDFDCK_02296 1.4e-124 K sequence-specific DNA binding
NEHDFDCK_02298 3.1e-10
NEHDFDCK_02299 1.4e-33
NEHDFDCK_02300 3.7e-148 L DNA replication protein
NEHDFDCK_02301 1.5e-266 S Virulence-associated protein E
NEHDFDCK_02302 7e-74
NEHDFDCK_02304 6.3e-49 S head-tail joining protein
NEHDFDCK_02305 3.1e-68 L HNH endonuclease
NEHDFDCK_02306 9.4e-83 terS L overlaps another CDS with the same product name
NEHDFDCK_02307 0.0 terL S overlaps another CDS with the same product name
NEHDFDCK_02309 9.4e-203 S Phage portal protein
NEHDFDCK_02310 3.4e-275 S Caudovirus prohead serine protease
NEHDFDCK_02311 3.1e-38 S Phage gp6-like head-tail connector protein
NEHDFDCK_02312 2.7e-61
NEHDFDCK_02315 8.9e-30
NEHDFDCK_02317 5.6e-219 int L Belongs to the 'phage' integrase family
NEHDFDCK_02318 4.8e-31
NEHDFDCK_02319 2.6e-11
NEHDFDCK_02323 4.1e-13 S DNA/RNA non-specific endonuclease
NEHDFDCK_02325 5.5e-10 E peptidase
NEHDFDCK_02326 4.9e-21 K transcriptional
NEHDFDCK_02327 5.9e-07
NEHDFDCK_02329 7.7e-54
NEHDFDCK_02330 2.3e-74
NEHDFDCK_02331 1.9e-09 S Domain of unknown function (DUF1508)
NEHDFDCK_02333 9.2e-55 S Bacteriophage Mu Gam like protein
NEHDFDCK_02334 1.4e-64
NEHDFDCK_02335 3.9e-165 L Domain of unknown function (DUF4373)
NEHDFDCK_02336 8.3e-50
NEHDFDCK_02337 9.9e-86
NEHDFDCK_02338 1.5e-62 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NEHDFDCK_02340 1.3e-33
NEHDFDCK_02342 9.4e-86 S methyltransferase activity
NEHDFDCK_02345 4e-21 S YopX protein
NEHDFDCK_02347 1.8e-14
NEHDFDCK_02350 1.6e-18 S KTSC domain
NEHDFDCK_02354 1.7e-13 V HNH nucleases
NEHDFDCK_02356 1.6e-48 L transposase activity
NEHDFDCK_02357 1.6e-188 S Phage terminase, large subunit, PBSX family
NEHDFDCK_02358 1.4e-114 S Phage portal protein, SPP1 Gp6-like
NEHDFDCK_02359 2.6e-46 S Phage minor capsid protein 2
NEHDFDCK_02361 2.6e-108
NEHDFDCK_02362 6e-07
NEHDFDCK_02363 4.6e-14
NEHDFDCK_02366 3.3e-10 S Minor capsid protein from bacteriophage
NEHDFDCK_02367 1.5e-35 N domain, Protein
NEHDFDCK_02369 7.3e-14 S Bacteriophage Gp15 protein
NEHDFDCK_02370 7.4e-118 M Phage tail tape measure protein TP901
NEHDFDCK_02371 2.2e-47 S Phage tail protein
NEHDFDCK_02372 1.8e-100 S Prophage endopeptidase tail
NEHDFDCK_02375 1.6e-207 S Domain of unknown function (DUF2479)
NEHDFDCK_02378 4.8e-08 S Phage uncharacterised protein (Phage_XkdX)
NEHDFDCK_02379 6.2e-170 M hydrolase, family 25
NEHDFDCK_02380 4.4e-46
NEHDFDCK_02381 2e-27 hol S Bacteriophage holin
NEHDFDCK_02384 6.9e-52 E Preprotein translocase subunit SecB
NEHDFDCK_02386 3.8e-135 yxkH G Polysaccharide deacetylase
NEHDFDCK_02387 3.3e-65 S Protein of unknown function (DUF1093)
NEHDFDCK_02388 0.0 ycfI V ABC transporter, ATP-binding protein
NEHDFDCK_02389 0.0 yfiC V ABC transporter
NEHDFDCK_02390 5.9e-124
NEHDFDCK_02391 1.9e-58
NEHDFDCK_02392 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NEHDFDCK_02393 1.5e-28
NEHDFDCK_02394 1e-190 ampC V Beta-lactamase
NEHDFDCK_02395 9.8e-196 manA 5.3.1.8 G mannose-6-phosphate isomerase
NEHDFDCK_02396 2.9e-136 cobQ S glutamine amidotransferase
NEHDFDCK_02397 1.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NEHDFDCK_02398 9.3e-109 tdk 2.7.1.21 F thymidine kinase
NEHDFDCK_02399 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEHDFDCK_02400 5.6e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEHDFDCK_02401 2.2e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NEHDFDCK_02402 1.1e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NEHDFDCK_02403 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NEHDFDCK_02404 1e-232 pyrP F Permease
NEHDFDCK_02405 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
NEHDFDCK_02406 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEHDFDCK_02407 3.9e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NEHDFDCK_02408 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEHDFDCK_02409 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NEHDFDCK_02410 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NEHDFDCK_02411 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEHDFDCK_02412 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NEHDFDCK_02413 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEHDFDCK_02414 4.7e-102 J Acetyltransferase (GNAT) domain
NEHDFDCK_02415 2.7e-180 mbl D Cell shape determining protein MreB Mrl
NEHDFDCK_02416 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NEHDFDCK_02417 3.3e-33 S Protein of unknown function (DUF2969)
NEHDFDCK_02418 9.3e-220 rodA D Belongs to the SEDS family
NEHDFDCK_02419 3.6e-48 gcsH2 E glycine cleavage
NEHDFDCK_02420 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEHDFDCK_02421 9.1e-111 metI U ABC transporter permease
NEHDFDCK_02422 2.2e-148 metQ M Belongs to the nlpA lipoprotein family
NEHDFDCK_02423 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
NEHDFDCK_02424 1.6e-177 S Protein of unknown function (DUF2785)
NEHDFDCK_02425 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NEHDFDCK_02426 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NEHDFDCK_02427 5.1e-295 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NEHDFDCK_02428 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NEHDFDCK_02429 1.2e-200 bla2 3.5.2.6 V Beta-lactamase enzyme family
NEHDFDCK_02430 6.2e-82 usp6 T universal stress protein
NEHDFDCK_02431 1.5e-38
NEHDFDCK_02432 8e-238 rarA L recombination factor protein RarA
NEHDFDCK_02433 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NEHDFDCK_02434 6.6e-44 czrA K Helix-turn-helix domain
NEHDFDCK_02435 7e-110 S Protein of unknown function (DUF1648)
NEHDFDCK_02436 1.1e-80 yueI S Protein of unknown function (DUF1694)
NEHDFDCK_02437 5.2e-113 yktB S Belongs to the UPF0637 family
NEHDFDCK_02438 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NEHDFDCK_02439 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
NEHDFDCK_02440 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NEHDFDCK_02441 1.6e-216 iscS2 2.8.1.7 E Aminotransferase class V
NEHDFDCK_02442 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NEHDFDCK_02443 7.5e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NEHDFDCK_02444 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NEHDFDCK_02445 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEHDFDCK_02446 4.7e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NEHDFDCK_02447 1.3e-116 radC L DNA repair protein
NEHDFDCK_02448 2.8e-161 mreB D cell shape determining protein MreB
NEHDFDCK_02449 2.6e-144 mreC M Involved in formation and maintenance of cell shape
NEHDFDCK_02450 1.6e-88 mreD M rod shape-determining protein MreD
NEHDFDCK_02451 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NEHDFDCK_02452 1.2e-146 minD D Belongs to the ParA family
NEHDFDCK_02453 4.6e-109 glnP P ABC transporter permease
NEHDFDCK_02454 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NEHDFDCK_02455 1.5e-155 aatB ET ABC transporter substrate-binding protein
NEHDFDCK_02456 1.8e-85 2.5.1.74 H UbiA prenyltransferase family
NEHDFDCK_02457 3.7e-31 tnp2PF3 L manually curated
NEHDFDCK_02458 1e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
NEHDFDCK_02459 4.2e-113 papP P ABC transporter, permease protein
NEHDFDCK_02460 9.7e-113 P ABC transporter permease
NEHDFDCK_02461 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NEHDFDCK_02462 9.1e-153 cjaA ET ABC transporter substrate-binding protein
NEHDFDCK_02463 3.6e-204 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHDFDCK_02464 8.2e-82 L Helix-turn-helix domain
NEHDFDCK_02465 1.9e-277 S Psort location CytoplasmicMembrane, score
NEHDFDCK_02466 4.4e-130 S haloacid dehalogenase-like hydrolase
NEHDFDCK_02467 7.7e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NEHDFDCK_02468 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
NEHDFDCK_02469 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
NEHDFDCK_02471 1.4e-201 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NEHDFDCK_02472 4.3e-46 L Transposase
NEHDFDCK_02474 5.2e-34
NEHDFDCK_02475 4.2e-144 soj D AAA domain
NEHDFDCK_02478 2.2e-38 sirR K Helix-turn-helix diphteria tox regulatory element
NEHDFDCK_02479 5.1e-250 mntH P H( )-stimulated, divalent metal cation uptake system
NEHDFDCK_02480 6.2e-57 T Belongs to the universal stress protein A family
NEHDFDCK_02481 1e-96 tnpR1 L Resolvase, N terminal domain
NEHDFDCK_02482 1.9e-54
NEHDFDCK_02483 3e-238 EGP Major Facilitator Superfamily
NEHDFDCK_02484 0.0 mco Q Multicopper oxidase
NEHDFDCK_02485 4.7e-25
NEHDFDCK_02487 6.9e-178 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEHDFDCK_02488 5.2e-28 M PFAM Glycosyl transferase, group 1
NEHDFDCK_02489 9.8e-61 L Transposase and inactivated derivatives, IS30 family
NEHDFDCK_02490 1.1e-15
NEHDFDCK_02491 1.3e-11 S Transglycosylase associated protein
NEHDFDCK_02492 1.6e-73 S cog cog1302
NEHDFDCK_02493 1.9e-23 S Small integral membrane protein (DUF2273)
NEHDFDCK_02494 1.3e-91
NEHDFDCK_02495 4.8e-148 3.4.13.21 E Belongs to the peptidase S51 family
NEHDFDCK_02496 2.3e-53 XK27_02070 S Nitroreductase
NEHDFDCK_02497 0.0 lacS G Transporter
NEHDFDCK_02498 5e-137 bgaR K helix_turn_helix, arabinose operon control protein
NEHDFDCK_02499 1.1e-150 pstS P Phosphate
NEHDFDCK_02500 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
NEHDFDCK_02501 1.5e-155 pstA P Phosphate transport system permease protein PstA
NEHDFDCK_02502 5.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEHDFDCK_02503 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEHDFDCK_02504 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
NEHDFDCK_02505 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
NEHDFDCK_02506 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NEHDFDCK_02507 5.3e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NEHDFDCK_02508 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEHDFDCK_02509 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NEHDFDCK_02510 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NEHDFDCK_02511 1.9e-124 yliE T Putative diguanylate phosphodiesterase
NEHDFDCK_02512 3.3e-269 nox C NADH oxidase
NEHDFDCK_02513 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NEHDFDCK_02514 2e-109 yviA S Protein of unknown function (DUF421)
NEHDFDCK_02515 1.1e-61 S Protein of unknown function (DUF3290)
NEHDFDCK_02516 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NEHDFDCK_02517 3.3e-132 yliE T Putative diguanylate phosphodiesterase
NEHDFDCK_02518 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NEHDFDCK_02519 2.5e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NEHDFDCK_02520 9.2e-212 norA EGP Major facilitator Superfamily
NEHDFDCK_02521 1.2e-117 yfbR S HD containing hydrolase-like enzyme
NEHDFDCK_02522 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NEHDFDCK_02523 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEHDFDCK_02524 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NEHDFDCK_02525 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NEHDFDCK_02526 7.2e-264 argH 4.3.2.1 E argininosuccinate lyase
NEHDFDCK_02527 9.3e-87 S Short repeat of unknown function (DUF308)
NEHDFDCK_02528 1.6e-160 rapZ S Displays ATPase and GTPase activities
NEHDFDCK_02529 2.9e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NEHDFDCK_02530 3.7e-168 whiA K May be required for sporulation
NEHDFDCK_02531 4e-306 oppA E ABC transporter, substratebinding protein
NEHDFDCK_02532 1e-176 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHDFDCK_02533 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEHDFDCK_02535 4.2e-245 rpoN K Sigma-54 factor, core binding domain
NEHDFDCK_02536 7.3e-189 cggR K Putative sugar-binding domain
NEHDFDCK_02537 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEHDFDCK_02538 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NEHDFDCK_02539 6.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEHDFDCK_02540 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEHDFDCK_02541 4.8e-133
NEHDFDCK_02542 6.6e-295 clcA P chloride
NEHDFDCK_02543 1.2e-30 secG U Preprotein translocase
NEHDFDCK_02544 8.5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
NEHDFDCK_02545 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NEHDFDCK_02546 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NEHDFDCK_02547 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
NEHDFDCK_02548 1.5e-256 glnP P ABC transporter
NEHDFDCK_02549 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NEHDFDCK_02550 6.1e-105 yxjI
NEHDFDCK_02551 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
NEHDFDCK_02552 6.3e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEHDFDCK_02553 4.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NEHDFDCK_02554 1.5e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NEHDFDCK_02555 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
NEHDFDCK_02556 1.1e-100 dnaQ 2.7.7.7 L DNA polymerase III
NEHDFDCK_02557 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
NEHDFDCK_02558 2.5e-161 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NEHDFDCK_02559 6.2e-168 murB 1.3.1.98 M Cell wall formation
NEHDFDCK_02560 0.0 yjcE P Sodium proton antiporter
NEHDFDCK_02561 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
NEHDFDCK_02562 7.1e-121 S Protein of unknown function (DUF1361)
NEHDFDCK_02563 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NEHDFDCK_02564 1.6e-129 ybbR S YbbR-like protein
NEHDFDCK_02565 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NEHDFDCK_02566 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEHDFDCK_02567 4.5e-123 yliE T EAL domain
NEHDFDCK_02568 7.8e-146 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
NEHDFDCK_02569 3.1e-104 K Bacterial regulatory proteins, tetR family
NEHDFDCK_02570 3.1e-71 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NEHDFDCK_02571 5.1e-104 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NEHDFDCK_02572 3.3e-52
NEHDFDCK_02573 3e-72
NEHDFDCK_02574 3e-131 1.5.1.39 C nitroreductase
NEHDFDCK_02575 4e-154 G Transmembrane secretion effector
NEHDFDCK_02576 1.7e-298 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEHDFDCK_02577 8.6e-142
NEHDFDCK_02579 1.9e-71 spxA 1.20.4.1 P ArsC family
NEHDFDCK_02580 1.5e-33
NEHDFDCK_02581 3.2e-89 V VanZ like family
NEHDFDCK_02582 6e-242 EGP Major facilitator Superfamily
NEHDFDCK_02583 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NEHDFDCK_02584 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NEHDFDCK_02585 1.8e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NEHDFDCK_02586 1.5e-152 licD M LicD family
NEHDFDCK_02587 1.3e-82 K Transcriptional regulator
NEHDFDCK_02588 1.5e-19
NEHDFDCK_02589 1.2e-225 pbuG S permease
NEHDFDCK_02590 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NEHDFDCK_02591 5.3e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NEHDFDCK_02592 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NEHDFDCK_02593 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NEHDFDCK_02594 3.5e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NEHDFDCK_02595 0.0 oatA I Acyltransferase
NEHDFDCK_02596 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NEHDFDCK_02597 5e-69 O OsmC-like protein
NEHDFDCK_02598 2.6e-46
NEHDFDCK_02599 1.1e-251 yfnA E Amino Acid
NEHDFDCK_02600 2.5e-88
NEHDFDCK_02601 1.9e-147 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NEHDFDCK_02602 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NEHDFDCK_02603 1.8e-19
NEHDFDCK_02604 6.3e-105 gmk2 2.7.4.8 F Guanylate kinase
NEHDFDCK_02605 3.7e-81 zur P Belongs to the Fur family
NEHDFDCK_02606 7.1e-12 3.2.1.14 GH18
NEHDFDCK_02607 4.9e-148
NEHDFDCK_02608 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NEHDFDCK_02609 3e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NEHDFDCK_02610 4.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHDFDCK_02611 3.6e-41
NEHDFDCK_02613 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NEHDFDCK_02614 7.8e-149 glnH ET ABC transporter substrate-binding protein
NEHDFDCK_02615 1.6e-109 gluC P ABC transporter permease
NEHDFDCK_02616 4e-108 glnP P ABC transporter permease
NEHDFDCK_02617 3.1e-50 tnpR1 L Resolvase, N terminal domain
NEHDFDCK_02618 4e-34 tnpR1 L Resolvase, N terminal domain
NEHDFDCK_02619 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding
NEHDFDCK_02620 1.5e-42 S COG NOG38524 non supervised orthologous group
NEHDFDCK_02621 5.5e-14 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEHDFDCK_02622 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
NEHDFDCK_02623 1.2e-23 S Family of unknown function (DUF5388)
NEHDFDCK_02624 4.2e-150 S Uncharacterised protein, DegV family COG1307
NEHDFDCK_02625 4.2e-86 M1-874 K Domain of unknown function (DUF1836)
NEHDFDCK_02626 1.7e-136 L Replication protein
NEHDFDCK_02627 6.7e-237 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NEHDFDCK_02628 2.9e-38 ylbB V ABC transporter permease
NEHDFDCK_02629 8.8e-151 glcU U sugar transport
NEHDFDCK_02630 3.3e-45 D protein tyrosine kinase activity
NEHDFDCK_02631 9.1e-24 V Beta-lactamase
NEHDFDCK_02633 6.9e-108 S CAAX protease self-immunity
NEHDFDCK_02634 1.2e-93 plnD K LytTr DNA-binding domain
NEHDFDCK_02635 1.3e-33 S Glycosyltransferase like family 2
NEHDFDCK_02636 1.2e-11 epsI GM Polysaccharide pyruvyl transferase
NEHDFDCK_02637 1.8e-184 aroF 2.5.1.54 E DAHP synthetase I family
NEHDFDCK_02638 1.2e-194 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NEHDFDCK_02639 1.4e-262 P Sodium:sulfate symporter transmembrane region
NEHDFDCK_02640 4.1e-53 yitW S Iron-sulfur cluster assembly protein
NEHDFDCK_02641 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
NEHDFDCK_02642 4.4e-177 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
NEHDFDCK_02643 1.9e-197 K Helix-turn-helix domain
NEHDFDCK_02644 3.6e-154 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NEHDFDCK_02645 9.9e-132 mntB 3.6.3.35 P ABC transporter
NEHDFDCK_02646 1.4e-140 mtsB U ABC 3 transport family
NEHDFDCK_02647 1.3e-173 sitA P Belongs to the bacterial solute-binding protein 9 family
NEHDFDCK_02648 3.1e-50
NEHDFDCK_02649 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NEHDFDCK_02650 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
NEHDFDCK_02651 2.9e-179 citR K sugar-binding domain protein
NEHDFDCK_02652 3e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
NEHDFDCK_02653 3.3e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NEHDFDCK_02654 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
NEHDFDCK_02655 2.7e-163 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NEHDFDCK_02656 7.8e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NEHDFDCK_02657 6.4e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NEHDFDCK_02658 2.7e-263 frdC 1.3.5.4 C FAD binding domain
NEHDFDCK_02659 1.2e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NEHDFDCK_02660 1.1e-161 mleR K LysR family transcriptional regulator
NEHDFDCK_02661 7.5e-166 mleR K LysR family
NEHDFDCK_02662 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NEHDFDCK_02663 1.4e-165 mleP S Sodium Bile acid symporter family
NEHDFDCK_02664 2.2e-252 yfnA E Amino Acid
NEHDFDCK_02665 3e-99 S ECF transporter, substrate-specific component
NEHDFDCK_02666 1.8e-23
NEHDFDCK_02667 2.8e-301 S Alpha beta
NEHDFDCK_02668 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
NEHDFDCK_02669 4.4e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NEHDFDCK_02670 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NEHDFDCK_02671 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NEHDFDCK_02672 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
NEHDFDCK_02673 2.4e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NEHDFDCK_02674 2.5e-164 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NEHDFDCK_02675 3.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
NEHDFDCK_02676 5.8e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
NEHDFDCK_02677 2e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NEHDFDCK_02678 1e-93 S UPF0316 protein
NEHDFDCK_02679 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NEHDFDCK_02680 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NEHDFDCK_02681 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEHDFDCK_02682 1.8e-196 camS S sex pheromone
NEHDFDCK_02683 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEHDFDCK_02684 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEHDFDCK_02685 2.9e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEHDFDCK_02686 1e-190 yegS 2.7.1.107 G Lipid kinase
NEHDFDCK_02687 1.4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEHDFDCK_02688 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
NEHDFDCK_02689 0.0 yfgQ P E1-E2 ATPase
NEHDFDCK_02690 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHDFDCK_02691 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
NEHDFDCK_02692 2.3e-151 gntR K rpiR family
NEHDFDCK_02693 1.1e-144 lys M Glycosyl hydrolases family 25
NEHDFDCK_02694 1.1e-62 S Domain of unknown function (DUF4828)
NEHDFDCK_02695 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
NEHDFDCK_02696 8.4e-190 mocA S Oxidoreductase
NEHDFDCK_02697 8.9e-240 yfmL 3.6.4.13 L DEAD DEAH box helicase
NEHDFDCK_02699 7.5e-81 int L Belongs to the 'phage' integrase family
NEHDFDCK_02703 7.9e-11 tcdC
NEHDFDCK_02704 2.3e-29 E Zn peptidase
NEHDFDCK_02705 9.3e-29 ps115 K Helix-turn-helix XRE-family like proteins
NEHDFDCK_02709 8.9e-64 S ORF6C domain
NEHDFDCK_02715 3.3e-19
NEHDFDCK_02717 5.7e-147 S Protein of unknown function (DUF1351)
NEHDFDCK_02718 1.5e-115 S AAA domain
NEHDFDCK_02719 5.1e-95 S Protein of unknown function (DUF669)
NEHDFDCK_02720 2.8e-120 S Putative HNHc nuclease
NEHDFDCK_02721 2.9e-41 ybl78 L Conserved phage C-terminus (Phg_2220_C)
NEHDFDCK_02722 1.7e-142 pi346 L IstB-like ATP binding protein
NEHDFDCK_02724 8.8e-85
NEHDFDCK_02725 8.6e-63 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NEHDFDCK_02726 8.8e-123 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NEHDFDCK_02727 2.5e-10 S YopX protein
NEHDFDCK_02728 8.7e-42
NEHDFDCK_02729 1.3e-18
NEHDFDCK_02730 5.1e-35 S Transcriptional regulator, RinA family
NEHDFDCK_02732 2e-07 V HNH nucleases
NEHDFDCK_02733 3.2e-89 L HNH nucleases
NEHDFDCK_02734 7.1e-80 S Phage terminase, small subunit
NEHDFDCK_02735 0.0 S Phage Terminase
NEHDFDCK_02736 5.6e-26 S Protein of unknown function (DUF1056)
NEHDFDCK_02737 1.8e-223 S Phage portal protein
NEHDFDCK_02738 2.1e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NEHDFDCK_02739 4.3e-212 S Phage capsid family
NEHDFDCK_02740 8.1e-49 S Phage gp6-like head-tail connector protein
NEHDFDCK_02741 2.2e-57 S Phage head-tail joining protein
NEHDFDCK_02742 2.9e-64 S Bacteriophage HK97-gp10, putative tail-component
NEHDFDCK_02743 7.8e-56 S Protein of unknown function (DUF806)
NEHDFDCK_02744 7.4e-107 S Phage tail tube protein
NEHDFDCK_02745 1.7e-58 S Phage tail assembly chaperone proteins, TAC
NEHDFDCK_02746 6.6e-24
NEHDFDCK_02747 0.0 M Phage tail tape measure protein TP901
NEHDFDCK_02748 1.7e-225 S Phage tail protein
NEHDFDCK_02749 3e-45 S Phage minor structural protein
NEHDFDCK_02750 1.5e-233 S Phage minor structural protein
NEHDFDCK_02751 3.6e-199
NEHDFDCK_02754 9.5e-77
NEHDFDCK_02755 6.8e-16
NEHDFDCK_02756 1.7e-202 lys M Glycosyl hydrolases family 25
NEHDFDCK_02757 5.3e-35 S Haemolysin XhlA
NEHDFDCK_02758 5.5e-25 hol S Bacteriophage holin
NEHDFDCK_02759 2.3e-75 T Universal stress protein family
NEHDFDCK_02760 4.1e-245 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHDFDCK_02761 1.8e-164 S Alpha/beta hydrolase of unknown function (DUF915)
NEHDFDCK_02763 1.1e-72
NEHDFDCK_02764 5e-107
NEHDFDCK_02765 1.7e-254 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NEHDFDCK_02766 1.7e-218 pbpX1 V Beta-lactamase
NEHDFDCK_02767 6.8e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NEHDFDCK_02768 1.3e-157 yihY S Belongs to the UPF0761 family
NEHDFDCK_02769 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NEHDFDCK_02770 1.3e-17 wcoI 2.7.10.1, 2.7.10.2 M biosynthesis protein
NEHDFDCK_02771 6e-75 Q Methyltransferase domain
NEHDFDCK_02772 2.5e-22 Q Methyltransferase domain
NEHDFDCK_02773 7.5e-39
NEHDFDCK_02774 2.7e-66 soj D AAA domain
NEHDFDCK_02776 4.4e-127 terC P integral membrane protein, YkoY family
NEHDFDCK_02777 1.6e-196 tra L Transposase and inactivated derivatives, IS30 family
NEHDFDCK_02778 1.6e-39 L Transposase
NEHDFDCK_02779 1.8e-92 L 4.5 Transposon and IS
NEHDFDCK_02780 1.6e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NEHDFDCK_02781 4e-113 L Integrase core domain
NEHDFDCK_02782 1e-154 L Integrase core domain
NEHDFDCK_02784 2.1e-08 S Short C-terminal domain
NEHDFDCK_02785 3.4e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
NEHDFDCK_02786 4.3e-65
NEHDFDCK_02787 5.4e-76
NEHDFDCK_02788 9.3e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NEHDFDCK_02789 2.9e-87
NEHDFDCK_02790 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NEHDFDCK_02791 2.9e-36 ynzC S UPF0291 protein
NEHDFDCK_02792 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
NEHDFDCK_02793 1.2e-117 plsC 2.3.1.51 I Acyltransferase
NEHDFDCK_02794 4.2e-133 yabB 2.1.1.223 L Methyltransferase small domain
NEHDFDCK_02795 1.8e-39 yazA L GIY-YIG catalytic domain protein
NEHDFDCK_02796 1.9e-186 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHDFDCK_02797 4.7e-134 S Haloacid dehalogenase-like hydrolase
NEHDFDCK_02798 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
NEHDFDCK_02799 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEHDFDCK_02800 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NEHDFDCK_02801 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEHDFDCK_02802 6.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEHDFDCK_02803 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
NEHDFDCK_02804 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NEHDFDCK_02805 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEHDFDCK_02806 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEHDFDCK_02807 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
NEHDFDCK_02808 3.3e-217 nusA K Participates in both transcription termination and antitermination
NEHDFDCK_02809 9.5e-49 ylxR K Protein of unknown function (DUF448)
NEHDFDCK_02810 1.1e-47 ylxQ J ribosomal protein
NEHDFDCK_02811 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEHDFDCK_02812 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEHDFDCK_02813 2.5e-264 ydiN 5.4.99.5 G Major Facilitator
NEHDFDCK_02814 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NEHDFDCK_02815 8.5e-93
NEHDFDCK_02816 5.5e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NEHDFDCK_02817 7.2e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NEHDFDCK_02818 1.7e-85 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NEHDFDCK_02819 9.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEHDFDCK_02820 4.9e-190 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NEHDFDCK_02821 2.5e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
NEHDFDCK_02822 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NEHDFDCK_02823 3e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEHDFDCK_02824 0.0 dnaK O Heat shock 70 kDa protein
NEHDFDCK_02825 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEHDFDCK_02826 4.4e-198 pbpX2 V Beta-lactamase
NEHDFDCK_02827 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
NEHDFDCK_02828 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHDFDCK_02829 2.5e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
NEHDFDCK_02830 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHDFDCK_02831 2.3e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NEHDFDCK_02832 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEHDFDCK_02833 1.4e-49
NEHDFDCK_02834 1.4e-49
NEHDFDCK_02835 6.8e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NEHDFDCK_02836 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
NEHDFDCK_02837 6.4e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NEHDFDCK_02838 3.7e-57
NEHDFDCK_02839 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEHDFDCK_02840 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEHDFDCK_02841 1.9e-115 3.1.3.18 J HAD-hyrolase-like
NEHDFDCK_02842 5.1e-164 yniA G Fructosamine kinase
NEHDFDCK_02843 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NEHDFDCK_02844 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
NEHDFDCK_02845 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NEHDFDCK_02846 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEHDFDCK_02847 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEHDFDCK_02848 2.9e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEHDFDCK_02849 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NEHDFDCK_02850 1.7e-128 C Enoyl-(Acyl carrier protein) reductase
NEHDFDCK_02851 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NEHDFDCK_02852 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NEHDFDCK_02853 1.3e-70 yqeY S YqeY-like protein
NEHDFDCK_02854 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
NEHDFDCK_02855 6.6e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEHDFDCK_02856 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NEHDFDCK_02857 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEHDFDCK_02858 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
NEHDFDCK_02859 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NEHDFDCK_02860 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NEHDFDCK_02861 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEHDFDCK_02862 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NEHDFDCK_02863 3.6e-64 K helix_turn_helix gluconate operon transcriptional repressor
NEHDFDCK_02864 1.1e-164 ytrB V ABC transporter, ATP-binding protein
NEHDFDCK_02865 7.8e-202
NEHDFDCK_02866 2.9e-54
NEHDFDCK_02867 1.5e-124
NEHDFDCK_02868 1.1e-125 S ABC-2 family transporter protein
NEHDFDCK_02869 4.7e-157 V ABC transporter, ATP-binding protein
NEHDFDCK_02870 3.8e-114 S Psort location CytoplasmicMembrane, score
NEHDFDCK_02871 1.6e-79 K MarR family
NEHDFDCK_02872 6e-82 K Acetyltransferase (GNAT) domain
NEHDFDCK_02874 5.2e-159 yvfR V ABC transporter
NEHDFDCK_02875 1.3e-134 yvfS V ABC-2 type transporter
NEHDFDCK_02876 2.2e-204 desK 2.7.13.3 T Histidine kinase
NEHDFDCK_02877 1.2e-103 desR K helix_turn_helix, Lux Regulon
NEHDFDCK_02878 2.5e-269 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NEHDFDCK_02879 1.8e-13 S Alpha beta hydrolase
NEHDFDCK_02880 6.7e-173 C nadph quinone reductase
NEHDFDCK_02881 2.1e-160 K Transcriptional regulator
NEHDFDCK_02882 9.8e-79 S Uncharacterized protein conserved in bacteria (DUF2255)
NEHDFDCK_02883 7.6e-112 GM NmrA-like family
NEHDFDCK_02884 7.7e-160 S Alpha beta hydrolase
NEHDFDCK_02885 6.5e-128 K Helix-turn-helix domain, rpiR family
NEHDFDCK_02886 1.1e-75 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
NEHDFDCK_02887 3.7e-117 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
NEHDFDCK_02888 0.0 CP_1020 S Zinc finger, swim domain protein
NEHDFDCK_02889 2e-112 GM epimerase
NEHDFDCK_02890 4.1e-68 S Protein of unknown function (DUF1722)
NEHDFDCK_02891 9.1e-71 yneH 1.20.4.1 P ArsC family
NEHDFDCK_02892 1.2e-106 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
NEHDFDCK_02893 1.8e-136 K DeoR C terminal sensor domain
NEHDFDCK_02894 3.7e-169 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NEHDFDCK_02895 1.3e-54 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NEHDFDCK_02896 1.4e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NEHDFDCK_02897 4.3e-77 K Transcriptional regulator
NEHDFDCK_02898 6.5e-241 EGP Major facilitator Superfamily
NEHDFDCK_02899 1.2e-191 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEHDFDCK_02902 5.4e-77 L Transposase DDE domain
NEHDFDCK_02903 5.1e-68 L Putative transposase of IS4/5 family (DUF4096)
NEHDFDCK_02904 9.8e-39 L Transposase and inactivated derivatives
NEHDFDCK_02905 2.7e-31 L Transposase
NEHDFDCK_02906 4.6e-45
NEHDFDCK_02907 2.3e-99 S WxL domain surface cell wall-binding
NEHDFDCK_02908 1.5e-118 S WxL domain surface cell wall-binding
NEHDFDCK_02909 1.4e-163 S Cell surface protein
NEHDFDCK_02910 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
NEHDFDCK_02911 8.4e-262 nox C NADH oxidase
NEHDFDCK_02912 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NEHDFDCK_02913 0.0 pepO 3.4.24.71 O Peptidase family M13
NEHDFDCK_02914 4.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NEHDFDCK_02915 1.6e-32 copZ P Heavy-metal-associated domain
NEHDFDCK_02916 6.6e-96 dps P Belongs to the Dps family
NEHDFDCK_02917 1.6e-18
NEHDFDCK_02918 6.2e-39 yrkD S Metal-sensitive transcriptional repressor
NEHDFDCK_02919 3.3e-55 txlA O Thioredoxin-like domain
NEHDFDCK_02920 2.4e-141 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NEHDFDCK_02921 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
NEHDFDCK_02922 6.2e-182 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
NEHDFDCK_02923 3.5e-126 ydcF S Gram-negative-bacterium-type cell wall biogenesis
NEHDFDCK_02924 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NEHDFDCK_02925 7.2e-183 yfeX P Peroxidase
NEHDFDCK_02926 1.6e-100 K transcriptional regulator
NEHDFDCK_02927 2.6e-159 4.1.1.46 S Amidohydrolase
NEHDFDCK_02928 2.5e-52 S Uncharacterized protein conserved in bacteria (DUF2316)
NEHDFDCK_02929 2.1e-108
NEHDFDCK_02930 5.8e-12 K Cro/C1-type HTH DNA-binding domain
NEHDFDCK_02931 3.7e-65 XK27_09885 V VanZ like family
NEHDFDCK_02932 5.6e-12
NEHDFDCK_02934 4.2e-62
NEHDFDCK_02935 2.5e-53
NEHDFDCK_02936 2.5e-75 mltD CBM50 M PFAM NLP P60 protein
NEHDFDCK_02937 1.1e-283 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NEHDFDCK_02938 1.8e-27
NEHDFDCK_02939 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NEHDFDCK_02940 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
NEHDFDCK_02941 1.2e-88 K Winged helix DNA-binding domain
NEHDFDCK_02942 1.3e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
NEHDFDCK_02943 1.7e-129 S WxL domain surface cell wall-binding
NEHDFDCK_02944 1.5e-186 S Bacterial protein of unknown function (DUF916)
NEHDFDCK_02945 0.0
NEHDFDCK_02946 7.9e-161 ypuA S Protein of unknown function (DUF1002)
NEHDFDCK_02947 5.5e-50 yvlA
NEHDFDCK_02948 1.2e-95 K transcriptional regulator
NEHDFDCK_02949 2.7e-91 ymdB S Macro domain protein
NEHDFDCK_02950 3.2e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NEHDFDCK_02951 2e-77 S Threonine/Serine exporter, ThrE
NEHDFDCK_02952 9.2e-133 thrE S Putative threonine/serine exporter
NEHDFDCK_02953 1.8e-164 yvgN C Aldo keto reductase
NEHDFDCK_02954 3.8e-152 ywkB S Membrane transport protein
NEHDFDCK_02955 6.4e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NEHDFDCK_02956 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
NEHDFDCK_02957 4.5e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
NEHDFDCK_02958 2.4e-189 L PFAM Integrase, catalytic core
NEHDFDCK_02959 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
NEHDFDCK_02960 6.8e-181 D Alpha beta
NEHDFDCK_02961 5.9e-214 mdtG EGP Major facilitator Superfamily
NEHDFDCK_02962 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
NEHDFDCK_02963 7.1e-65 ycgX S Protein of unknown function (DUF1398)
NEHDFDCK_02964 1.1e-49
NEHDFDCK_02965 3.4e-25
NEHDFDCK_02966 3.3e-248 lmrB EGP Major facilitator Superfamily
NEHDFDCK_02967 5.9e-73 S COG NOG18757 non supervised orthologous group
NEHDFDCK_02968 7.4e-40
NEHDFDCK_02969 9.4e-74 copR K Copper transport repressor CopY TcrY
NEHDFDCK_02970 0.0 copB 3.6.3.4 P P-type ATPase
NEHDFDCK_02971 4.1e-189 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NEHDFDCK_02972 1.4e-111 S VIT family
NEHDFDCK_02973 1.8e-119 S membrane
NEHDFDCK_02974 1.6e-158 EG EamA-like transporter family
NEHDFDCK_02975 3.8e-81 elaA S GNAT family
NEHDFDCK_02976 9.6e-115 GM NmrA-like family
NEHDFDCK_02977 2.1e-14
NEHDFDCK_02978 7e-56
NEHDFDCK_02979 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
NEHDFDCK_02980 1.6e-85
NEHDFDCK_02981 1.9e-62
NEHDFDCK_02982 3.5e-213 mutY L A G-specific adenine glycosylase
NEHDFDCK_02983 4e-53
NEHDFDCK_02984 1.4e-65 yeaO S Protein of unknown function, DUF488
NEHDFDCK_02985 1.7e-69 spx4 1.20.4.1 P ArsC family
NEHDFDCK_02986 9.2e-66 K Winged helix DNA-binding domain
NEHDFDCK_02987 4.8e-162 azoB GM NmrA-like family
NEHDFDCK_02988 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NEHDFDCK_02989 4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
NEHDFDCK_02990 2.6e-250 cycA E Amino acid permease
NEHDFDCK_02991 1.2e-255 nhaC C Na H antiporter NhaC
NEHDFDCK_02992 6.1e-27 3.2.2.10 S Belongs to the LOG family
NEHDFDCK_02993 1.3e-199 frlB M SIS domain
NEHDFDCK_02994 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NEHDFDCK_02995 1e-218 S Uncharacterized protein conserved in bacteria (DUF2325)
NEHDFDCK_02996 3.4e-123 yyaQ S YjbR
NEHDFDCK_02998 0.0 cadA P P-type ATPase
NEHDFDCK_02999 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
NEHDFDCK_03000 5.8e-120 E GDSL-like Lipase/Acylhydrolase family
NEHDFDCK_03001 1.4e-77
NEHDFDCK_03002 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
NEHDFDCK_03003 3.3e-97 FG HIT domain
NEHDFDCK_03004 5e-173 S Aldo keto reductase
NEHDFDCK_03005 3.3e-52 yitW S Pfam:DUF59
NEHDFDCK_03006 1.9e-160 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEHDFDCK_03007 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
NEHDFDCK_03008 5e-195 blaA6 V Beta-lactamase
NEHDFDCK_03009 6.2e-96 V VanZ like family
NEHDFDCK_03012 4.9e-160 lmrA 3.6.3.44 V ABC transporter
NEHDFDCK_03013 1.1e-95 rmaB K Transcriptional regulator, MarR family
NEHDFDCK_03014 1.3e-119 drgA C Nitroreductase family
NEHDFDCK_03015 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
NEHDFDCK_03016 6.4e-117 cmpC S ATPases associated with a variety of cellular activities
NEHDFDCK_03017 2.3e-124 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
NEHDFDCK_03018 3.5e-169 XK27_00670 S ABC transporter
NEHDFDCK_03019 1e-260
NEHDFDCK_03020 8.6e-63
NEHDFDCK_03021 2.5e-189 S Cell surface protein
NEHDFDCK_03022 1e-91 S WxL domain surface cell wall-binding
NEHDFDCK_03023 2.4e-97 acuB S Domain in cystathionine beta-synthase and other proteins.
NEHDFDCK_03024 3.3e-124 livF E ABC transporter
NEHDFDCK_03025 1.8e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
NEHDFDCK_03026 5.3e-141 livM E Branched-chain amino acid transport system / permease component
NEHDFDCK_03027 2.5e-128 livH U Branched-chain amino acid transport system / permease component
NEHDFDCK_03028 5.4e-212 livJ E Receptor family ligand binding region
NEHDFDCK_03030 7e-33
NEHDFDCK_03031 3.5e-114 zmp3 O Zinc-dependent metalloprotease
NEHDFDCK_03032 2.8e-82 gtrA S GtrA-like protein
NEHDFDCK_03033 3.2e-121 K Helix-turn-helix XRE-family like proteins
NEHDFDCK_03034 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
NEHDFDCK_03035 8.8e-72 T Belongs to the universal stress protein A family
NEHDFDCK_03036 1.1e-46
NEHDFDCK_03037 1.9e-116 S SNARE associated Golgi protein
NEHDFDCK_03038 1.9e-47 K Transcriptional regulator, ArsR family
NEHDFDCK_03039 1.2e-95 cadD P Cadmium resistance transporter
NEHDFDCK_03040 0.0 yhcA V ABC transporter, ATP-binding protein
NEHDFDCK_03041 0.0 P Concanavalin A-like lectin/glucanases superfamily
NEHDFDCK_03042 1.7e-63
NEHDFDCK_03043 1.3e-159 T Calcineurin-like phosphoesterase superfamily domain
NEHDFDCK_03044 3.2e-55
NEHDFDCK_03045 3.8e-148 dicA K Helix-turn-helix domain
NEHDFDCK_03046 2e-74 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEHDFDCK_03047 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NEHDFDCK_03048 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHDFDCK_03049 2.4e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NEHDFDCK_03050 5.9e-183 1.1.1.219 GM Male sterility protein
NEHDFDCK_03051 5.1e-75 K helix_turn_helix, mercury resistance
NEHDFDCK_03052 1.3e-63 M LysM domain
NEHDFDCK_03053 8.7e-95 M Lysin motif
NEHDFDCK_03054 3.4e-39 S SdpI/YhfL protein family
NEHDFDCK_03055 1.8e-54 nudA S ASCH
NEHDFDCK_03056 2.7e-163 psaA P Belongs to the bacterial solute-binding protein 9 family
NEHDFDCK_03057 1.1e-92
NEHDFDCK_03058 1.3e-119 tag 3.2.2.20 L Methyladenine glycosylase
NEHDFDCK_03059 3.3e-219 T diguanylate cyclase
NEHDFDCK_03060 1.2e-73 S Psort location Cytoplasmic, score
NEHDFDCK_03061 4e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
NEHDFDCK_03062 5.6e-217 ykiI
NEHDFDCK_03063 0.0 V ABC transporter
NEHDFDCK_03064 2.9e-310 XK27_09600 V ABC transporter, ATP-binding protein
NEHDFDCK_03065 7.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
NEHDFDCK_03066 1.3e-162 IQ KR domain
NEHDFDCK_03068 3.7e-70
NEHDFDCK_03069 1.9e-144 K Helix-turn-helix XRE-family like proteins
NEHDFDCK_03070 4.7e-266 yjeM E Amino Acid
NEHDFDCK_03071 3.9e-66 lysM M LysM domain
NEHDFDCK_03072 1.6e-146 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
NEHDFDCK_03073 1.9e-178 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
NEHDFDCK_03074 0.0 ctpA 3.6.3.54 P P-type ATPase
NEHDFDCK_03075 1.7e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NEHDFDCK_03076 7e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NEHDFDCK_03077 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NEHDFDCK_03078 6e-140 K Helix-turn-helix domain
NEHDFDCK_03079 5.5e-37 S TfoX C-terminal domain
NEHDFDCK_03080 1.1e-226 hpk9 2.7.13.3 T GHKL domain
NEHDFDCK_03081 1.9e-262
NEHDFDCK_03082 1.3e-75
NEHDFDCK_03083 1.5e-189 S Cell surface protein
NEHDFDCK_03084 1.7e-101 S WxL domain surface cell wall-binding
NEHDFDCK_03085 2.3e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
NEHDFDCK_03086 1.3e-66 S Iron-sulphur cluster biosynthesis
NEHDFDCK_03087 3.6e-114 S GyrI-like small molecule binding domain
NEHDFDCK_03088 3.4e-186 S Cell surface protein
NEHDFDCK_03090 2e-101 S WxL domain surface cell wall-binding
NEHDFDCK_03091 1.1e-62
NEHDFDCK_03092 1.9e-215 NU Mycoplasma protein of unknown function, DUF285
NEHDFDCK_03093 2.3e-116
NEHDFDCK_03094 3e-116 S Haloacid dehalogenase-like hydrolase
NEHDFDCK_03095 2e-61 K Transcriptional regulator, HxlR family
NEHDFDCK_03096 4.9e-213 ytbD EGP Major facilitator Superfamily
NEHDFDCK_03097 1.4e-94 M ErfK YbiS YcfS YnhG
NEHDFDCK_03098 0.0 asnB 6.3.5.4 E Asparagine synthase
NEHDFDCK_03099 5.7e-135 K LytTr DNA-binding domain
NEHDFDCK_03100 3e-205 2.7.13.3 T GHKL domain
NEHDFDCK_03101 7.9e-100 fadR K Bacterial regulatory proteins, tetR family
NEHDFDCK_03102 1.1e-167 GM NmrA-like family
NEHDFDCK_03103 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NEHDFDCK_03104 1.3e-58 M Glycosyl hydrolases family 25

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)