ORF_ID e_value Gene_name EC_number CAZy COGs Description
IOAFOGIE_00002 4.6e-163 K Transcriptional regulator
IOAFOGIE_00003 7e-161 akr5f 1.1.1.346 S reductase
IOAFOGIE_00004 9.5e-166 S Oxidoreductase, aldo keto reductase family protein
IOAFOGIE_00005 3e-78 K Winged helix DNA-binding domain
IOAFOGIE_00006 2.2e-268 ycaM E amino acid
IOAFOGIE_00007 8.3e-129 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
IOAFOGIE_00008 1.7e-31
IOAFOGIE_00009 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
IOAFOGIE_00010 0.0 M Bacterial Ig-like domain (group 3)
IOAFOGIE_00011 1.1e-77 fld C Flavodoxin
IOAFOGIE_00012 5.3e-234
IOAFOGIE_00013 4.6e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IOAFOGIE_00014 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IOAFOGIE_00015 8.3e-152 EG EamA-like transporter family
IOAFOGIE_00016 4.2e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOAFOGIE_00017 9.8e-152 S hydrolase
IOAFOGIE_00018 4.1e-81
IOAFOGIE_00019 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IOAFOGIE_00020 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
IOAFOGIE_00021 1.8e-130 gntR K UTRA
IOAFOGIE_00022 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IOAFOGIE_00023 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
IOAFOGIE_00024 9.5e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOAFOGIE_00025 9.8e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOAFOGIE_00026 8.2e-246 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
IOAFOGIE_00027 6.9e-133 V AAA domain, putative AbiEii toxin, Type IV TA system
IOAFOGIE_00028 2e-153 V ABC transporter
IOAFOGIE_00029 2.2e-117 K Transcriptional regulator
IOAFOGIE_00030 6.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOAFOGIE_00031 3.6e-88 niaR S 3H domain
IOAFOGIE_00032 3.9e-224 EGP Major facilitator Superfamily
IOAFOGIE_00033 2.1e-232 S Sterol carrier protein domain
IOAFOGIE_00034 4.2e-211 S Bacterial protein of unknown function (DUF871)
IOAFOGIE_00035 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
IOAFOGIE_00036 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
IOAFOGIE_00037 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
IOAFOGIE_00038 1.1e-101 3.6.1.13 L Belongs to the Nudix hydrolase family
IOAFOGIE_00039 1.7e-111 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IOAFOGIE_00040 4.4e-11 mcbG S Pentapeptide repeats (8 copies)
IOAFOGIE_00041 5e-145 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
IOAFOGIE_00042 5.2e-281 thrC 4.2.3.1 E Threonine synthase
IOAFOGIE_00043 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
IOAFOGIE_00045 1.5e-52
IOAFOGIE_00046 3.5e-117
IOAFOGIE_00047 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
IOAFOGIE_00048 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
IOAFOGIE_00050 5e-51
IOAFOGIE_00051 2.8e-87
IOAFOGIE_00052 2.1e-70 gtcA S Teichoic acid glycosylation protein
IOAFOGIE_00053 4e-34
IOAFOGIE_00054 6.7e-81 uspA T universal stress protein
IOAFOGIE_00055 5.8e-149
IOAFOGIE_00056 6.7e-151 V ABC transporter, ATP-binding protein
IOAFOGIE_00057 7.9e-61 gntR1 K Transcriptional regulator, GntR family
IOAFOGIE_00058 8e-42
IOAFOGIE_00059 0.0 V FtsX-like permease family
IOAFOGIE_00060 1.7e-139 cysA V ABC transporter, ATP-binding protein
IOAFOGIE_00061 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
IOAFOGIE_00062 7.5e-149 S Alpha/beta hydrolase of unknown function (DUF915)
IOAFOGIE_00063 9.2e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
IOAFOGIE_00064 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
IOAFOGIE_00065 1.3e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
IOAFOGIE_00066 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
IOAFOGIE_00067 1.5e-223 XK27_09615 1.3.5.4 S reductase
IOAFOGIE_00068 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOAFOGIE_00069 7.4e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOAFOGIE_00070 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IOAFOGIE_00071 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOAFOGIE_00072 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOAFOGIE_00073 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOAFOGIE_00074 1.1e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOAFOGIE_00075 3.8e-190 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IOAFOGIE_00076 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IOAFOGIE_00077 1e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IOAFOGIE_00078 9.3e-215 purD 6.3.4.13 F Belongs to the GARS family
IOAFOGIE_00079 3.9e-127 2.1.1.14 E Methionine synthase
IOAFOGIE_00080 4.6e-252 pgaC GT2 M Glycosyl transferase
IOAFOGIE_00081 2.6e-94
IOAFOGIE_00082 3.1e-74 T EAL domain
IOAFOGIE_00083 2.3e-94
IOAFOGIE_00084 0.0 typA T GTP-binding protein TypA
IOAFOGIE_00085 6.3e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IOAFOGIE_00086 3.3e-46 yktA S Belongs to the UPF0223 family
IOAFOGIE_00087 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
IOAFOGIE_00088 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
IOAFOGIE_00089 5.2e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOAFOGIE_00090 4.5e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
IOAFOGIE_00091 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IOAFOGIE_00092 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOAFOGIE_00093 1.6e-85
IOAFOGIE_00094 3.1e-33 ykzG S Belongs to the UPF0356 family
IOAFOGIE_00095 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOAFOGIE_00096 1.7e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IOAFOGIE_00097 1.7e-28
IOAFOGIE_00098 4.1e-108 mltD CBM50 M NlpC P60 family protein
IOAFOGIE_00099 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOAFOGIE_00100 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IOAFOGIE_00101 2.1e-120 S Repeat protein
IOAFOGIE_00102 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IOAFOGIE_00103 1.3e-263 N domain, Protein
IOAFOGIE_00104 3.7e-193 S Bacterial protein of unknown function (DUF916)
IOAFOGIE_00105 2.3e-120 N WxL domain surface cell wall-binding
IOAFOGIE_00106 2.6e-115 ktrA P domain protein
IOAFOGIE_00107 1.3e-241 ktrB P Potassium uptake protein
IOAFOGIE_00108 9.1e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IOAFOGIE_00109 4.9e-57 XK27_04120 S Putative amino acid metabolism
IOAFOGIE_00110 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
IOAFOGIE_00111 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOAFOGIE_00112 4.6e-28
IOAFOGIE_00113 5.6e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IOAFOGIE_00114 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IOAFOGIE_00115 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOAFOGIE_00116 1.2e-86 divIVA D DivIVA domain protein
IOAFOGIE_00117 1.3e-145 ylmH S S4 domain protein
IOAFOGIE_00118 1.2e-36 yggT S YGGT family
IOAFOGIE_00119 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOAFOGIE_00120 2.8e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOAFOGIE_00121 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IOAFOGIE_00122 1.7e-162 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IOAFOGIE_00123 1.5e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOAFOGIE_00124 1.4e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOAFOGIE_00125 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOAFOGIE_00126 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IOAFOGIE_00127 7.5e-54 ftsL D Cell division protein FtsL
IOAFOGIE_00128 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOAFOGIE_00129 1.9e-77 mraZ K Belongs to the MraZ family
IOAFOGIE_00130 1.9e-62 S Protein of unknown function (DUF3397)
IOAFOGIE_00131 1.2e-174 corA P CorA-like Mg2+ transporter protein
IOAFOGIE_00132 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IOAFOGIE_00133 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOAFOGIE_00134 5.3e-113 ywnB S NAD(P)H-binding
IOAFOGIE_00135 9.8e-210 brnQ U Component of the transport system for branched-chain amino acids
IOAFOGIE_00137 2.4e-161 rrmA 2.1.1.187 H Methyltransferase
IOAFOGIE_00138 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOAFOGIE_00139 4.3e-206 XK27_05220 S AI-2E family transporter
IOAFOGIE_00140 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IOAFOGIE_00141 7.4e-194 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IOAFOGIE_00142 5.1e-116 cutC P Participates in the control of copper homeostasis
IOAFOGIE_00143 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
IOAFOGIE_00144 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOAFOGIE_00145 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
IOAFOGIE_00146 3.6e-114 yjbH Q Thioredoxin
IOAFOGIE_00147 0.0 pepF E oligoendopeptidase F
IOAFOGIE_00148 7.6e-205 coiA 3.6.4.12 S Competence protein
IOAFOGIE_00149 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IOAFOGIE_00150 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IOAFOGIE_00151 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
IOAFOGIE_00152 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IOAFOGIE_00162 5.5e-08
IOAFOGIE_00174 1.4e-117 S Domain of unknown function (DUF4811)
IOAFOGIE_00175 7e-270 lmrB EGP Major facilitator Superfamily
IOAFOGIE_00176 1.7e-84 merR K MerR HTH family regulatory protein
IOAFOGIE_00177 5.8e-58
IOAFOGIE_00178 2e-120 sirR K iron dependent repressor
IOAFOGIE_00179 6e-31 cspC K Cold shock protein
IOAFOGIE_00180 1.5e-130 thrE S Putative threonine/serine exporter
IOAFOGIE_00181 2.2e-76 S Threonine/Serine exporter, ThrE
IOAFOGIE_00182 1.2e-163 L PFAM Integrase catalytic region
IOAFOGIE_00183 1.7e-88 L Helix-turn-helix domain
IOAFOGIE_00184 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOAFOGIE_00185 2.3e-119 lssY 3.6.1.27 I phosphatase
IOAFOGIE_00186 2e-154 I alpha/beta hydrolase fold
IOAFOGIE_00187 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
IOAFOGIE_00188 4.2e-92 K Transcriptional regulator
IOAFOGIE_00189 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IOAFOGIE_00190 1.5e-264 lysP E amino acid
IOAFOGIE_00191 2.5e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IOAFOGIE_00192 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IOAFOGIE_00193 2.7e-217 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOAFOGIE_00201 6.9e-78 ctsR K Belongs to the CtsR family
IOAFOGIE_00202 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOAFOGIE_00203 4.3e-109 K Bacterial regulatory proteins, tetR family
IOAFOGIE_00204 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOAFOGIE_00205 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOAFOGIE_00206 3.2e-116 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IOAFOGIE_00207 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOAFOGIE_00208 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOAFOGIE_00209 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOAFOGIE_00210 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IOAFOGIE_00211 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOAFOGIE_00212 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
IOAFOGIE_00213 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOAFOGIE_00214 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOAFOGIE_00215 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOAFOGIE_00216 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOAFOGIE_00217 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOAFOGIE_00218 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOAFOGIE_00219 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
IOAFOGIE_00220 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOAFOGIE_00221 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOAFOGIE_00222 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOAFOGIE_00223 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOAFOGIE_00224 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOAFOGIE_00225 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOAFOGIE_00226 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOAFOGIE_00227 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOAFOGIE_00228 2.2e-24 rpmD J Ribosomal protein L30
IOAFOGIE_00229 6.3e-70 rplO J Binds to the 23S rRNA
IOAFOGIE_00230 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOAFOGIE_00231 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOAFOGIE_00232 3.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOAFOGIE_00233 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOAFOGIE_00234 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOAFOGIE_00235 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOAFOGIE_00236 2.1e-61 rplQ J Ribosomal protein L17
IOAFOGIE_00237 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOAFOGIE_00238 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
IOAFOGIE_00239 1.4e-86 ynhH S NusG domain II
IOAFOGIE_00240 0.0 ndh 1.6.99.3 C NADH dehydrogenase
IOAFOGIE_00241 3.5e-142 cad S FMN_bind
IOAFOGIE_00242 2e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOAFOGIE_00243 4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOAFOGIE_00244 6.3e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOAFOGIE_00245 1.2e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOAFOGIE_00246 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOAFOGIE_00247 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOAFOGIE_00248 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IOAFOGIE_00249 2.3e-164 degV S Uncharacterised protein, DegV family COG1307
IOAFOGIE_00250 1.9e-184 ywhK S Membrane
IOAFOGIE_00251 7.6e-205 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IOAFOGIE_00252 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IOAFOGIE_00253 8.3e-165 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IOAFOGIE_00254 2.1e-64 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IOAFOGIE_00255 1.6e-58
IOAFOGIE_00257 2.2e-151 S IstB-like ATP binding protein
IOAFOGIE_00258 3.1e-30 3.1.3.16 L DnaD domain protein
IOAFOGIE_00259 6.9e-56
IOAFOGIE_00260 9.2e-55 S Bacteriophage Mu Gam like protein
IOAFOGIE_00263 6.6e-96
IOAFOGIE_00265 1.3e-16
IOAFOGIE_00266 8.6e-12
IOAFOGIE_00267 7.3e-13
IOAFOGIE_00268 9.7e-41 S protein disulfide oxidoreductase activity
IOAFOGIE_00269 1.2e-12 E IrrE N-terminal-like domain
IOAFOGIE_00270 4.5e-113 M Host cell surface-exposed lipoprotein
IOAFOGIE_00274 8.4e-229 L Belongs to the 'phage' integrase family
IOAFOGIE_00276 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOAFOGIE_00277 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOAFOGIE_00278 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOAFOGIE_00279 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOAFOGIE_00280 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
IOAFOGIE_00281 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
IOAFOGIE_00282 3.4e-28 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOAFOGIE_00283 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IOAFOGIE_00284 2.4e-101 sigH K Sigma-70 region 2
IOAFOGIE_00285 5.3e-98 yacP S YacP-like NYN domain
IOAFOGIE_00286 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOAFOGIE_00287 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IOAFOGIE_00288 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOAFOGIE_00289 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOAFOGIE_00290 3.7e-205 yacL S domain protein
IOAFOGIE_00291 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOAFOGIE_00292 1.1e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IOAFOGIE_00293 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
IOAFOGIE_00294 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IOAFOGIE_00295 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
IOAFOGIE_00296 5.2e-113 zmp2 O Zinc-dependent metalloprotease
IOAFOGIE_00297 9.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOAFOGIE_00298 8.3e-177 EG EamA-like transporter family
IOAFOGIE_00299 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IOAFOGIE_00300 4.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOAFOGIE_00301 4.1e-136 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
IOAFOGIE_00302 8.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IOAFOGIE_00303 7.5e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
IOAFOGIE_00304 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
IOAFOGIE_00305 7.8e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOAFOGIE_00306 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
IOAFOGIE_00307 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
IOAFOGIE_00308 0.0 levR K Sigma-54 interaction domain
IOAFOGIE_00309 4.7e-64 S Domain of unknown function (DUF956)
IOAFOGIE_00310 4.4e-169 manN G system, mannose fructose sorbose family IID component
IOAFOGIE_00311 3.4e-133 manY G PTS system
IOAFOGIE_00312 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
IOAFOGIE_00313 2.1e-151 G Peptidase_C39 like family
IOAFOGIE_00315 2.9e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOAFOGIE_00316 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IOAFOGIE_00317 1.2e-82 ydcK S Belongs to the SprT family
IOAFOGIE_00318 0.0 yhgF K Tex-like protein N-terminal domain protein
IOAFOGIE_00319 8.9e-72
IOAFOGIE_00320 0.0 pacL 3.6.3.8 P P-type ATPase
IOAFOGIE_00321 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IOAFOGIE_00322 1.5e-288 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOAFOGIE_00323 1.2e-137 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IOAFOGIE_00324 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
IOAFOGIE_00325 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IOAFOGIE_00326 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOAFOGIE_00327 3.7e-151 pnuC H nicotinamide mononucleotide transporter
IOAFOGIE_00328 1.2e-192 ybiR P Citrate transporter
IOAFOGIE_00329 4.9e-167 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
IOAFOGIE_00330 2.5e-53 S Cupin domain
IOAFOGIE_00331 3.5e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
IOAFOGIE_00335 2e-151 yjjH S Calcineurin-like phosphoesterase
IOAFOGIE_00336 3e-252 dtpT U amino acid peptide transporter
IOAFOGIE_00339 1.8e-20 S Short C-terminal domain
IOAFOGIE_00342 2.9e-43 L HTH-like domain
IOAFOGIE_00343 3.4e-36 L transposase activity
IOAFOGIE_00344 3.2e-60 L Belongs to the 'phage' integrase family
IOAFOGIE_00347 1.6e-31
IOAFOGIE_00348 1.9e-141 Q Methyltransferase
IOAFOGIE_00349 8.5e-57 ybjQ S Belongs to the UPF0145 family
IOAFOGIE_00350 2.1e-211 EGP Major facilitator Superfamily
IOAFOGIE_00351 1e-102 K Helix-turn-helix domain
IOAFOGIE_00352 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOAFOGIE_00353 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IOAFOGIE_00354 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
IOAFOGIE_00355 1.1e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IOAFOGIE_00356 2.8e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IOAFOGIE_00357 1.2e-45
IOAFOGIE_00358 6.9e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOAFOGIE_00359 1.5e-135 fruR K DeoR C terminal sensor domain
IOAFOGIE_00360 5.1e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IOAFOGIE_00361 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
IOAFOGIE_00362 6.5e-251 cpdA S Calcineurin-like phosphoesterase
IOAFOGIE_00363 4.1e-262 cps4J S Polysaccharide biosynthesis protein
IOAFOGIE_00364 2.4e-173 cps4I M Glycosyltransferase like family 2
IOAFOGIE_00365 1.2e-228
IOAFOGIE_00366 7.5e-178 cps4G M Glycosyltransferase Family 4
IOAFOGIE_00367 9.3e-174 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
IOAFOGIE_00368 1.8e-127 tuaA M Bacterial sugar transferase
IOAFOGIE_00369 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
IOAFOGIE_00370 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
IOAFOGIE_00371 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IOAFOGIE_00372 2.9e-126 epsB M biosynthesis protein
IOAFOGIE_00373 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOAFOGIE_00374 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOAFOGIE_00375 9.2e-270 glnPH2 P ABC transporter permease
IOAFOGIE_00376 4.3e-22
IOAFOGIE_00377 9.9e-73 S Iron-sulphur cluster biosynthesis
IOAFOGIE_00378 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
IOAFOGIE_00379 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
IOAFOGIE_00380 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOAFOGIE_00381 1.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOAFOGIE_00382 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOAFOGIE_00383 2.5e-156 S Tetratricopeptide repeat
IOAFOGIE_00384 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOAFOGIE_00385 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOAFOGIE_00386 3.7e-192 mdtG EGP Major Facilitator Superfamily
IOAFOGIE_00387 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOAFOGIE_00388 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
IOAFOGIE_00389 1.1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
IOAFOGIE_00390 0.0 comEC S Competence protein ComEC
IOAFOGIE_00391 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
IOAFOGIE_00392 8.2e-120 comEA L Competence protein ComEA
IOAFOGIE_00393 2.4e-195 ylbL T Belongs to the peptidase S16 family
IOAFOGIE_00394 1.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOAFOGIE_00395 1.2e-100 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IOAFOGIE_00396 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IOAFOGIE_00397 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IOAFOGIE_00398 1.6e-205 ftsW D Belongs to the SEDS family
IOAFOGIE_00399 3.2e-37
IOAFOGIE_00400 5.4e-213
IOAFOGIE_00401 5.1e-259 ica2 GT2 M Glycosyl transferase family group 2
IOAFOGIE_00402 1.2e-103
IOAFOGIE_00403 2.3e-100
IOAFOGIE_00404 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
IOAFOGIE_00405 9.4e-231 ymfF S Peptidase M16 inactive domain protein
IOAFOGIE_00406 2.9e-251 ymfH S Peptidase M16
IOAFOGIE_00407 5.7e-110 ymfM S Helix-turn-helix domain
IOAFOGIE_00408 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOAFOGIE_00409 9.4e-231 cinA 3.5.1.42 S Belongs to the CinA family
IOAFOGIE_00410 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOAFOGIE_00411 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
IOAFOGIE_00412 2.7e-154 ymdB S YmdB-like protein
IOAFOGIE_00413 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IOAFOGIE_00414 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IOAFOGIE_00415 1.3e-72
IOAFOGIE_00416 0.0 S Bacterial membrane protein YfhO
IOAFOGIE_00417 3.2e-92
IOAFOGIE_00418 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOAFOGIE_00419 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOAFOGIE_00420 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IOAFOGIE_00421 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IOAFOGIE_00422 2.8e-29 yajC U Preprotein translocase
IOAFOGIE_00423 5.9e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOAFOGIE_00424 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IOAFOGIE_00425 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IOAFOGIE_00426 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOAFOGIE_00427 2.4e-43 yrzL S Belongs to the UPF0297 family
IOAFOGIE_00428 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOAFOGIE_00429 1.6e-48 yrzB S Belongs to the UPF0473 family
IOAFOGIE_00430 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IOAFOGIE_00431 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOAFOGIE_00432 7.3e-52 trxA O Belongs to the thioredoxin family
IOAFOGIE_00433 1.9e-92 yslB S Protein of unknown function (DUF2507)
IOAFOGIE_00434 4.1e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IOAFOGIE_00435 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOAFOGIE_00436 1.2e-94 S Phosphoesterase
IOAFOGIE_00437 6.5e-87 ykuL S (CBS) domain
IOAFOGIE_00438 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IOAFOGIE_00439 1.7e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IOAFOGIE_00440 2.6e-158 ykuT M mechanosensitive ion channel
IOAFOGIE_00441 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IOAFOGIE_00442 2.8e-56
IOAFOGIE_00443 7.2e-80 K helix_turn_helix, mercury resistance
IOAFOGIE_00444 1.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IOAFOGIE_00445 1.9e-181 ccpA K catabolite control protein A
IOAFOGIE_00446 2.3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IOAFOGIE_00447 1.7e-48 S DsrE/DsrF-like family
IOAFOGIE_00448 8.3e-131 yebC K Transcriptional regulatory protein
IOAFOGIE_00449 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOAFOGIE_00450 2.1e-174 comGA NU Type II IV secretion system protein
IOAFOGIE_00451 7.4e-189 comGB NU type II secretion system
IOAFOGIE_00452 5.5e-43 comGC U competence protein ComGC
IOAFOGIE_00453 3.2e-83 gspG NU general secretion pathway protein
IOAFOGIE_00454 8.6e-20
IOAFOGIE_00455 6.5e-87 S Prokaryotic N-terminal methylation motif
IOAFOGIE_00457 4.2e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
IOAFOGIE_00458 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOAFOGIE_00459 1.2e-252 cycA E Amino acid permease
IOAFOGIE_00460 8.2e-116 S Calcineurin-like phosphoesterase
IOAFOGIE_00461 3.9e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IOAFOGIE_00462 1.5e-80 yutD S Protein of unknown function (DUF1027)
IOAFOGIE_00463 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IOAFOGIE_00464 4.6e-117 S Protein of unknown function (DUF1461)
IOAFOGIE_00465 3e-119 dedA S SNARE-like domain protein
IOAFOGIE_00466 9.4e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOAFOGIE_00467 1.6e-75 yugI 5.3.1.9 J general stress protein
IOAFOGIE_00468 1e-63
IOAFOGIE_00469 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IOAFOGIE_00470 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOAFOGIE_00471 2.4e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOAFOGIE_00472 5.9e-183 1.1.1.219 GM Male sterility protein
IOAFOGIE_00473 5.1e-75 K helix_turn_helix, mercury resistance
IOAFOGIE_00474 1.3e-63 M LysM domain
IOAFOGIE_00475 8.7e-95 M Lysin motif
IOAFOGIE_00476 3.4e-39 S SdpI/YhfL protein family
IOAFOGIE_00477 1.8e-54 nudA S ASCH
IOAFOGIE_00478 2.7e-163 psaA P Belongs to the bacterial solute-binding protein 9 family
IOAFOGIE_00479 1.1e-92
IOAFOGIE_00480 1.3e-119 tag 3.2.2.20 L Methyladenine glycosylase
IOAFOGIE_00481 3.3e-219 T diguanylate cyclase
IOAFOGIE_00482 1.2e-73 S Psort location Cytoplasmic, score
IOAFOGIE_00483 4e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
IOAFOGIE_00484 5.6e-217 ykiI
IOAFOGIE_00485 0.0 V ABC transporter
IOAFOGIE_00486 2.9e-310 XK27_09600 V ABC transporter, ATP-binding protein
IOAFOGIE_00487 7.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
IOAFOGIE_00488 1.3e-162 IQ KR domain
IOAFOGIE_00490 3.7e-70
IOAFOGIE_00491 1.9e-144 K Helix-turn-helix XRE-family like proteins
IOAFOGIE_00492 9.6e-267 yjeM E Amino Acid
IOAFOGIE_00493 3.9e-66 lysM M LysM domain
IOAFOGIE_00494 1.6e-146 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
IOAFOGIE_00495 4.9e-179 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
IOAFOGIE_00496 0.0 ctpA 3.6.3.54 P P-type ATPase
IOAFOGIE_00497 1.7e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IOAFOGIE_00498 7e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IOAFOGIE_00499 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IOAFOGIE_00500 6e-140 K Helix-turn-helix domain
IOAFOGIE_00501 5.5e-37 S TfoX C-terminal domain
IOAFOGIE_00502 1.1e-226 hpk9 2.7.13.3 T GHKL domain
IOAFOGIE_00503 1.9e-262
IOAFOGIE_00504 1.3e-75
IOAFOGIE_00505 1.5e-189 S Cell surface protein
IOAFOGIE_00506 1.7e-101 S WxL domain surface cell wall-binding
IOAFOGIE_00507 2.3e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
IOAFOGIE_00508 1.3e-66 S Iron-sulphur cluster biosynthesis
IOAFOGIE_00509 3.6e-114 S GyrI-like small molecule binding domain
IOAFOGIE_00510 3.4e-186 S Cell surface protein
IOAFOGIE_00512 2e-101 S WxL domain surface cell wall-binding
IOAFOGIE_00513 1.1e-62
IOAFOGIE_00514 1.9e-215 NU Mycoplasma protein of unknown function, DUF285
IOAFOGIE_00515 2.3e-116
IOAFOGIE_00516 3e-116 S Haloacid dehalogenase-like hydrolase
IOAFOGIE_00517 2e-61 K Transcriptional regulator, HxlR family
IOAFOGIE_00518 4.9e-213 ytbD EGP Major facilitator Superfamily
IOAFOGIE_00519 1.4e-94 M ErfK YbiS YcfS YnhG
IOAFOGIE_00520 0.0 asnB 6.3.5.4 E Asparagine synthase
IOAFOGIE_00521 1.3e-134 K LytTr DNA-binding domain
IOAFOGIE_00522 3e-205 2.7.13.3 T GHKL domain
IOAFOGIE_00523 7.9e-100 fadR K Bacterial regulatory proteins, tetR family
IOAFOGIE_00524 1.1e-167 GM NmrA-like family
IOAFOGIE_00525 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IOAFOGIE_00526 1.2e-59 M Glycosyl hydrolases family 25
IOAFOGIE_00527 1.7e-63 L Transposase
IOAFOGIE_00528 2.4e-22 plnF
IOAFOGIE_00529 4.3e-22
IOAFOGIE_00530 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IOAFOGIE_00531 8.9e-243 mesE M Transport protein ComB
IOAFOGIE_00532 5.9e-110 S CAAX protease self-immunity
IOAFOGIE_00533 1.7e-15 ypbD S CAAX protease self-immunity
IOAFOGIE_00534 2e-68 ypbD S CAAX protease self-immunity
IOAFOGIE_00535 8.4e-100 V CAAX protease self-immunity
IOAFOGIE_00536 1e-114 S CAAX protease self-immunity
IOAFOGIE_00537 1.8e-30
IOAFOGIE_00538 0.0 helD 3.6.4.12 L DNA helicase
IOAFOGIE_00539 1.1e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
IOAFOGIE_00540 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOAFOGIE_00541 1.2e-126 K UbiC transcription regulator-associated domain protein
IOAFOGIE_00542 2.5e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOAFOGIE_00543 3.9e-24
IOAFOGIE_00544 2.6e-76 S Domain of unknown function (DUF3284)
IOAFOGIE_00545 5.7e-250 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOAFOGIE_00546 1.4e-291 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOAFOGIE_00547 2e-163 GK ROK family
IOAFOGIE_00548 4.1e-133 K Helix-turn-helix domain, rpiR family
IOAFOGIE_00549 1.4e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOAFOGIE_00550 3.1e-167 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IOAFOGIE_00551 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IOAFOGIE_00552 3.1e-178
IOAFOGIE_00553 3.9e-133 cobB K SIR2 family
IOAFOGIE_00554 2e-160 yunF F Protein of unknown function DUF72
IOAFOGIE_00555 2.6e-70 mutT 3.6.1.55 F DNA mismatch repair protein MutT
IOAFOGIE_00556 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOAFOGIE_00557 1.3e-213 bcr1 EGP Major facilitator Superfamily
IOAFOGIE_00558 1.5e-146 tatD L hydrolase, TatD family
IOAFOGIE_00559 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IOAFOGIE_00560 8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOAFOGIE_00561 3.2e-37 veg S Biofilm formation stimulator VEG
IOAFOGIE_00562 2.2e-162 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IOAFOGIE_00563 1.5e-180 S Prolyl oligopeptidase family
IOAFOGIE_00564 2.8e-128 fhuC 3.6.3.35 P ABC transporter
IOAFOGIE_00565 9.2e-131 znuB U ABC 3 transport family
IOAFOGIE_00566 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IOAFOGIE_00567 1.2e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOAFOGIE_00568 1.8e-150 bla1 3.5.2.6 V Beta-lactamase enzyme family
IOAFOGIE_00569 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOAFOGIE_00570 2.5e-181 S DUF218 domain
IOAFOGIE_00571 4.1e-125
IOAFOGIE_00572 4.9e-148 yxeH S hydrolase
IOAFOGIE_00573 9e-264 ywfO S HD domain protein
IOAFOGIE_00574 1.8e-153 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
IOAFOGIE_00575 3.8e-78 ywiB S Domain of unknown function (DUF1934)
IOAFOGIE_00576 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IOAFOGIE_00577 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOAFOGIE_00578 4e-245 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOAFOGIE_00579 3.1e-229 tdcC E amino acid
IOAFOGIE_00580 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IOAFOGIE_00581 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IOAFOGIE_00582 6.4e-131 S YheO-like PAS domain
IOAFOGIE_00583 2.5e-26
IOAFOGIE_00584 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOAFOGIE_00585 6.6e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IOAFOGIE_00586 7.8e-41 rpmE2 J Ribosomal protein L31
IOAFOGIE_00588 2.1e-08 S Short C-terminal domain
IOAFOGIE_00589 3.4e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
IOAFOGIE_00590 4.3e-65
IOAFOGIE_00591 5.4e-76
IOAFOGIE_00592 9.3e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IOAFOGIE_00593 2.9e-87
IOAFOGIE_00594 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOAFOGIE_00595 2.9e-36 ynzC S UPF0291 protein
IOAFOGIE_00596 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
IOAFOGIE_00597 1.2e-117 plsC 2.3.1.51 I Acyltransferase
IOAFOGIE_00598 4.2e-133 yabB 2.1.1.223 L Methyltransferase small domain
IOAFOGIE_00599 1.8e-39 yazA L GIY-YIG catalytic domain protein
IOAFOGIE_00600 1.9e-186 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOAFOGIE_00601 4.7e-134 S Haloacid dehalogenase-like hydrolase
IOAFOGIE_00602 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
IOAFOGIE_00603 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOAFOGIE_00604 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IOAFOGIE_00605 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOAFOGIE_00606 6.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOAFOGIE_00607 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
IOAFOGIE_00608 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IOAFOGIE_00609 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOAFOGIE_00610 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOAFOGIE_00611 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
IOAFOGIE_00612 3.3e-217 nusA K Participates in both transcription termination and antitermination
IOAFOGIE_00613 9.5e-49 ylxR K Protein of unknown function (DUF448)
IOAFOGIE_00614 1.1e-47 ylxQ J ribosomal protein
IOAFOGIE_00615 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOAFOGIE_00616 1.7e-49 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOAFOGIE_00617 2.5e-264 ydiN 5.4.99.5 G Major Facilitator
IOAFOGIE_00618 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IOAFOGIE_00619 8.5e-93
IOAFOGIE_00620 5.5e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IOAFOGIE_00621 7.2e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IOAFOGIE_00622 1.7e-85 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IOAFOGIE_00623 9.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOAFOGIE_00624 4.9e-190 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IOAFOGIE_00625 2.5e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
IOAFOGIE_00626 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOAFOGIE_00627 3e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOAFOGIE_00628 0.0 dnaK O Heat shock 70 kDa protein
IOAFOGIE_00629 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOAFOGIE_00630 4.4e-198 pbpX2 V Beta-lactamase
IOAFOGIE_00631 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
IOAFOGIE_00632 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOAFOGIE_00633 2.5e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
IOAFOGIE_00634 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOAFOGIE_00635 2.3e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IOAFOGIE_00636 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOAFOGIE_00637 1.4e-49
IOAFOGIE_00638 1.4e-49
IOAFOGIE_00639 6.8e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IOAFOGIE_00640 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
IOAFOGIE_00641 6.4e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IOAFOGIE_00642 3.7e-57
IOAFOGIE_00643 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOAFOGIE_00644 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOAFOGIE_00645 1.9e-115 3.1.3.18 J HAD-hyrolase-like
IOAFOGIE_00646 1.3e-147 S Bacterial membrane protein, YfhO
IOAFOGIE_00647 4.1e-226 nupG F Nucleoside
IOAFOGIE_00648 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IOAFOGIE_00649 2.7e-149 noc K Belongs to the ParB family
IOAFOGIE_00650 1.8e-136 soj D Sporulation initiation inhibitor
IOAFOGIE_00651 4.8e-157 spo0J K Belongs to the ParB family
IOAFOGIE_00652 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
IOAFOGIE_00653 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOAFOGIE_00654 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
IOAFOGIE_00655 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOAFOGIE_00656 2.6e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOAFOGIE_00657 5.5e-124 yoaK S Protein of unknown function (DUF1275)
IOAFOGIE_00658 3.2e-124 K response regulator
IOAFOGIE_00659 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
IOAFOGIE_00660 4.2e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IOAFOGIE_00661 2.9e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IOAFOGIE_00662 5.1e-131 azlC E branched-chain amino acid
IOAFOGIE_00663 2.3e-54 azlD S branched-chain amino acid
IOAFOGIE_00664 1.8e-109 S membrane transporter protein
IOAFOGIE_00665 4.1e-54
IOAFOGIE_00667 1.5e-74 S Psort location Cytoplasmic, score
IOAFOGIE_00668 6e-97 S Domain of unknown function (DUF4352)
IOAFOGIE_00669 2.9e-23 S Protein of unknown function (DUF4064)
IOAFOGIE_00670 2.3e-28 KLT Protein tyrosine kinase
IOAFOGIE_00671 6.2e-145 KLT Protein tyrosine kinase
IOAFOGIE_00672 1.8e-162
IOAFOGIE_00673 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IOAFOGIE_00674 2.4e-83
IOAFOGIE_00675 2.9e-210 xylR GK ROK family
IOAFOGIE_00676 1.9e-171 K AI-2E family transporter
IOAFOGIE_00677 3.9e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOAFOGIE_00678 7.4e-31
IOAFOGIE_00679 3.7e-131 L Transposase and inactivated derivatives, IS30 family
IOAFOGIE_00680 6.5e-29 L Transposase and inactivated derivatives, IS30 family
IOAFOGIE_00681 1.2e-71 dptF L COG0433 Predicted ATPase
IOAFOGIE_00682 1.9e-56 dptG
IOAFOGIE_00683 6.9e-259 S Domain of unknown function DUF87
IOAFOGIE_00685 1.7e-18
IOAFOGIE_00687 2.8e-20 polA 2.7.7.7 L 3'-5' exonuclease
IOAFOGIE_00689 9.8e-116 S Phage plasmid primase, P4
IOAFOGIE_00691 6.8e-60 L Phage integrase SAM-like domain
IOAFOGIE_00694 1.2e-09 S Mor transcription activator family
IOAFOGIE_00695 6e-16
IOAFOGIE_00696 4.5e-23 S Mor transcription activator family
IOAFOGIE_00697 1e-29
IOAFOGIE_00698 1.2e-10 S Mor transcription activator family
IOAFOGIE_00699 1.7e-76
IOAFOGIE_00700 4e-41
IOAFOGIE_00701 5.1e-36 3.1.3.16 S Protein of unknown function (DUF1643)
IOAFOGIE_00702 7.1e-137 L Phage integrase SAM-like domain
IOAFOGIE_00703 0.0 L Restriction endonuclease
IOAFOGIE_00704 3.1e-222 M domain protein
IOAFOGIE_00705 1.8e-122 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IOAFOGIE_00706 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
IOAFOGIE_00707 5.7e-299 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOAFOGIE_00708 2.2e-254 gshR 1.8.1.7 C Pyridine nucleotide-disulphide oxidoreductase
IOAFOGIE_00709 2.9e-179 proV E ABC transporter, ATP-binding protein
IOAFOGIE_00710 1.8e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOAFOGIE_00711 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
IOAFOGIE_00712 3.2e-172
IOAFOGIE_00713 6.1e-155
IOAFOGIE_00714 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
IOAFOGIE_00715 4.5e-174 rihC 3.2.2.1 F Nucleoside
IOAFOGIE_00716 1.4e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IOAFOGIE_00717 9.3e-80
IOAFOGIE_00718 1.6e-82 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
IOAFOGIE_00719 1.6e-232 flhF N Uncharacterized conserved protein (DUF2075)
IOAFOGIE_00720 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
IOAFOGIE_00721 1.1e-54 ypaA S Protein of unknown function (DUF1304)
IOAFOGIE_00722 4.6e-309 mco Q Multicopper oxidase
IOAFOGIE_00723 1.8e-119 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
IOAFOGIE_00724 2e-100 zmp1 O Zinc-dependent metalloprotease
IOAFOGIE_00725 3.7e-44
IOAFOGIE_00726 2e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IOAFOGIE_00727 2.3e-240 amtB P ammonium transporter
IOAFOGIE_00728 7.9e-258 P Major Facilitator Superfamily
IOAFOGIE_00729 3.9e-93 K Transcriptional regulator PadR-like family
IOAFOGIE_00730 8.4e-44
IOAFOGIE_00731 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IOAFOGIE_00732 3.5e-154 tagG U Transport permease protein
IOAFOGIE_00733 3.8e-218
IOAFOGIE_00734 3.3e-222 mtnE 2.6.1.83 E Aminotransferase
IOAFOGIE_00735 7.7e-148 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOAFOGIE_00736 1.1e-86 metI U Binding-protein-dependent transport system inner membrane component
IOAFOGIE_00737 6.7e-126 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOAFOGIE_00738 2.2e-111 metQ P NLPA lipoprotein
IOAFOGIE_00739 1.4e-51 S CHY zinc finger
IOAFOGIE_00740 1.9e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IOAFOGIE_00741 6.8e-96 bioY S BioY family
IOAFOGIE_00742 3e-40
IOAFOGIE_00743 1.7e-281 pipD E Dipeptidase
IOAFOGIE_00744 1.5e-29
IOAFOGIE_00745 3e-122 qmcA O prohibitin homologues
IOAFOGIE_00746 3.4e-239 xylP1 G MFS/sugar transport protein
IOAFOGIE_00748 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IOAFOGIE_00749 3.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
IOAFOGIE_00750 4.9e-190
IOAFOGIE_00751 2e-163 ytrB V ABC transporter
IOAFOGIE_00752 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
IOAFOGIE_00753 8.1e-22
IOAFOGIE_00754 1.1e-89 K acetyltransferase
IOAFOGIE_00755 1e-84 K GNAT family
IOAFOGIE_00756 1.1e-83 6.3.3.2 S ASCH
IOAFOGIE_00757 5e-96 puuR K Cupin domain
IOAFOGIE_00758 3.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IOAFOGIE_00759 2e-149 potB P ABC transporter permease
IOAFOGIE_00760 3.4e-141 potC P ABC transporter permease
IOAFOGIE_00761 4e-206 potD P ABC transporter
IOAFOGIE_00762 6.2e-39
IOAFOGIE_00763 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
IOAFOGIE_00764 1.9e-74 K Transcriptional regulator
IOAFOGIE_00765 2.5e-77 elaA S GNAT family
IOAFOGIE_00766 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOAFOGIE_00767 6.8e-57
IOAFOGIE_00768 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
IOAFOGIE_00769 1.3e-131
IOAFOGIE_00770 2.9e-64 sepS16B
IOAFOGIE_00771 6.2e-90 sepS16B
IOAFOGIE_00772 9.7e-67 gcvH E Glycine cleavage H-protein
IOAFOGIE_00773 1.8e-52 lytE M LysM domain protein
IOAFOGIE_00774 8.5e-52 M Lysin motif
IOAFOGIE_00775 1e-120 S CAAX protease self-immunity
IOAFOGIE_00776 2.5e-114 V CAAX protease self-immunity
IOAFOGIE_00777 7.1e-121 yclH V ABC transporter
IOAFOGIE_00778 1.7e-194 yclI V MacB-like periplasmic core domain
IOAFOGIE_00779 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
IOAFOGIE_00780 1e-107 tag 3.2.2.20 L glycosylase
IOAFOGIE_00781 0.0 ydgH S MMPL family
IOAFOGIE_00782 3.1e-104 K transcriptional regulator
IOAFOGIE_00783 2.7e-123 2.7.6.5 S RelA SpoT domain protein
IOAFOGIE_00784 1.3e-47
IOAFOGIE_00785 6.4e-257 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
IOAFOGIE_00786 7.2e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOAFOGIE_00787 2.1e-41
IOAFOGIE_00788 9.9e-57
IOAFOGIE_00789 2.2e-120 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOAFOGIE_00790 2.2e-111 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOAFOGIE_00791 3.5e-129 yidA K Helix-turn-helix domain, rpiR family
IOAFOGIE_00792 1.8e-49
IOAFOGIE_00793 4.4e-129 K Transcriptional regulatory protein, C terminal
IOAFOGIE_00794 2.3e-251 T PhoQ Sensor
IOAFOGIE_00795 9.5e-65 K helix_turn_helix, mercury resistance
IOAFOGIE_00796 9.7e-253 ydiC1 EGP Major facilitator Superfamily
IOAFOGIE_00797 1e-40
IOAFOGIE_00798 5.2e-42
IOAFOGIE_00799 5.5e-118
IOAFOGIE_00800 8.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
IOAFOGIE_00801 4.3e-121 K Bacterial regulatory proteins, tetR family
IOAFOGIE_00802 1.8e-72 K Transcriptional regulator
IOAFOGIE_00803 1.6e-70
IOAFOGIE_00804 6.3e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IOAFOGIE_00805 1.4e-144
IOAFOGIE_00806 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
IOAFOGIE_00807 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
IOAFOGIE_00808 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
IOAFOGIE_00809 3.5e-129 treR K UTRA
IOAFOGIE_00810 3.7e-42
IOAFOGIE_00811 7.3e-43 S Protein of unknown function (DUF2089)
IOAFOGIE_00812 9.5e-141 pnuC H nicotinamide mononucleotide transporter
IOAFOGIE_00813 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
IOAFOGIE_00814 2.2e-165 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IOAFOGIE_00815 1.4e-209 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IOAFOGIE_00816 7.2e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
IOAFOGIE_00817 3.5e-97 yieF S NADPH-dependent FMN reductase
IOAFOGIE_00818 4.9e-254 S Uncharacterized protein conserved in bacteria (DUF2252)
IOAFOGIE_00819 3.9e-81 ndk 2.7.4.6 F Belongs to the NDK family
IOAFOGIE_00820 2.9e-61
IOAFOGIE_00821 2.5e-95
IOAFOGIE_00822 1.2e-49
IOAFOGIE_00823 6.2e-57 trxA1 O Belongs to the thioredoxin family
IOAFOGIE_00824 2.9e-75
IOAFOGIE_00825 9.5e-222 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
IOAFOGIE_00826 6.6e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOAFOGIE_00827 0.0 mtlR K Mga helix-turn-helix domain
IOAFOGIE_00828 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
IOAFOGIE_00829 2.6e-277 pipD E Dipeptidase
IOAFOGIE_00830 3.1e-98 K Helix-turn-helix domain
IOAFOGIE_00831 2.7e-224 1.3.5.4 C FAD dependent oxidoreductase
IOAFOGIE_00832 1e-173 P Major Facilitator Superfamily
IOAFOGIE_00833 3.7e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOAFOGIE_00834 2.4e-66
IOAFOGIE_00835 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOAFOGIE_00836 4.1e-158 dkgB S reductase
IOAFOGIE_00837 2.4e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IOAFOGIE_00838 3.1e-101 S ABC transporter permease
IOAFOGIE_00839 6.9e-259 P ABC transporter
IOAFOGIE_00840 1.8e-116 P cobalt transport
IOAFOGIE_00841 9.5e-262 S ATPases associated with a variety of cellular activities
IOAFOGIE_00842 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOAFOGIE_00843 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOAFOGIE_00845 1.7e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOAFOGIE_00846 4e-164 FbpA K Domain of unknown function (DUF814)
IOAFOGIE_00847 1.3e-60 S Domain of unknown function (DU1801)
IOAFOGIE_00848 4.9e-34
IOAFOGIE_00849 5e-179 yghZ C Aldo keto reductase family protein
IOAFOGIE_00850 8.7e-113 pgm1 G phosphoglycerate mutase
IOAFOGIE_00851 7.8e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IOAFOGIE_00852 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOAFOGIE_00853 1.3e-78 yiaC K Acetyltransferase (GNAT) domain
IOAFOGIE_00854 1.8e-309 oppA E ABC transporter, substratebinding protein
IOAFOGIE_00855 0.0 oppA E ABC transporter, substratebinding protein
IOAFOGIE_00856 1e-156 hipB K Helix-turn-helix
IOAFOGIE_00858 0.0 3.6.4.13 M domain protein
IOAFOGIE_00859 7.7e-166 mleR K LysR substrate binding domain
IOAFOGIE_00860 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IOAFOGIE_00861 1.1e-217 nhaC C Na H antiporter NhaC
IOAFOGIE_00862 1.3e-165 3.5.1.10 C nadph quinone reductase
IOAFOGIE_00863 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IOAFOGIE_00864 1.5e-172 scrR K Transcriptional regulator, LacI family
IOAFOGIE_00865 2.4e-302 scrB 3.2.1.26 GH32 G invertase
IOAFOGIE_00866 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
IOAFOGIE_00867 0.0 rafA 3.2.1.22 G alpha-galactosidase
IOAFOGIE_00868 3.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IOAFOGIE_00869 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
IOAFOGIE_00870 0.0 3.2.1.96 G Glycosyl hydrolase family 85
IOAFOGIE_00871 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IOAFOGIE_00872 4e-209 msmK P Belongs to the ABC transporter superfamily
IOAFOGIE_00873 1.5e-258 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
IOAFOGIE_00874 5.3e-150 malA S maltodextrose utilization protein MalA
IOAFOGIE_00875 1.4e-161 malD P ABC transporter permease
IOAFOGIE_00876 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
IOAFOGIE_00877 2.7e-230 mdxE G Bacterial extracellular solute-binding protein
IOAFOGIE_00878 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
IOAFOGIE_00879 5.7e-180 yvdE K helix_turn _helix lactose operon repressor
IOAFOGIE_00880 2.9e-190 malR K Transcriptional regulator, LacI family
IOAFOGIE_00881 8.6e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IOAFOGIE_00882 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
IOAFOGIE_00883 1.9e-101 dhaL 2.7.1.121 S Dak2
IOAFOGIE_00884 2.5e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IOAFOGIE_00885 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IOAFOGIE_00886 1.1e-92 K Bacterial regulatory proteins, tetR family
IOAFOGIE_00887 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
IOAFOGIE_00888 1.2e-275 C Electron transfer flavoprotein FAD-binding domain
IOAFOGIE_00889 1.2e-115 K Transcriptional regulator
IOAFOGIE_00890 4.6e-299 M Exporter of polyketide antibiotics
IOAFOGIE_00891 6.7e-170 yjjC V ABC transporter
IOAFOGIE_00892 1.2e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
IOAFOGIE_00893 9.1e-89
IOAFOGIE_00894 4.7e-151
IOAFOGIE_00895 2.5e-83
IOAFOGIE_00896 1.8e-44
IOAFOGIE_00897 8.3e-54 K Transcriptional regulator PadR-like family
IOAFOGIE_00898 1.6e-129 K UbiC transcription regulator-associated domain protein
IOAFOGIE_00899 2.5e-98 S UPF0397 protein
IOAFOGIE_00900 0.0 ykoD P ABC transporter, ATP-binding protein
IOAFOGIE_00901 7.1e-150 cbiQ P cobalt transport
IOAFOGIE_00902 8.9e-69 C Oxidoreductase
IOAFOGIE_00903 6.3e-128 C Oxidoreductase
IOAFOGIE_00904 7.8e-256
IOAFOGIE_00905 3.7e-47
IOAFOGIE_00906 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
IOAFOGIE_00907 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
IOAFOGIE_00908 1.2e-165 1.1.1.65 C Aldo keto reductase
IOAFOGIE_00909 7.6e-160 S reductase
IOAFOGIE_00911 2e-89 yeaN P Transporter, major facilitator family protein
IOAFOGIE_00912 1.6e-106 yeaN P Transporter, major facilitator family protein
IOAFOGIE_00913 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
IOAFOGIE_00914 4.7e-227 mdtG EGP Major facilitator Superfamily
IOAFOGIE_00915 5.8e-82 S Protein of unknown function (DUF3021)
IOAFOGIE_00916 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
IOAFOGIE_00917 1.2e-74 papX3 K Transcriptional regulator
IOAFOGIE_00918 1.3e-110 S NADPH-dependent FMN reductase
IOAFOGIE_00919 1.6e-28 KT PspC domain
IOAFOGIE_00920 0.0 pacL1 P P-type ATPase
IOAFOGIE_00921 1.3e-98 S CRISPR-associated protein (Cas_Csn2)
IOAFOGIE_00922 6.3e-48 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IOAFOGIE_00923 2.4e-156 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IOAFOGIE_00924 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IOAFOGIE_00925 1.1e-149 ydjP I Alpha/beta hydrolase family
IOAFOGIE_00926 2.6e-121
IOAFOGIE_00927 2.6e-250 yifK E Amino acid permease
IOAFOGIE_00928 3.4e-85 F NUDIX domain
IOAFOGIE_00929 1.4e-303 L HIRAN domain
IOAFOGIE_00930 1.6e-137 S peptidase C26
IOAFOGIE_00931 1.4e-207 cytX U Belongs to the purine-cytosine permease (2.A.39) family
IOAFOGIE_00932 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IOAFOGIE_00933 5e-148 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IOAFOGIE_00934 7.1e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IOAFOGIE_00935 4.2e-178 1.6.5.5 C Zinc-binding dehydrogenase
IOAFOGIE_00936 2.8e-151 larE S NAD synthase
IOAFOGIE_00937 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IOAFOGIE_00938 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
IOAFOGIE_00939 6.9e-131 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
IOAFOGIE_00940 2.4e-125 larB S AIR carboxylase
IOAFOGIE_00941 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
IOAFOGIE_00942 4.6e-120 K Crp-like helix-turn-helix domain
IOAFOGIE_00943 1.6e-180 nikMN P PDGLE domain
IOAFOGIE_00944 1.2e-149 P Cobalt transport protein
IOAFOGIE_00945 3.9e-128 cbiO P ABC transporter
IOAFOGIE_00946 4.8e-40
IOAFOGIE_00947 1.4e-139 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
IOAFOGIE_00949 7e-141
IOAFOGIE_00950 1.9e-303 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
IOAFOGIE_00951 6e-76
IOAFOGIE_00952 2.9e-139 S Belongs to the UPF0246 family
IOAFOGIE_00953 2.2e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
IOAFOGIE_00954 1.9e-234 mepA V MATE efflux family protein
IOAFOGIE_00955 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
IOAFOGIE_00956 4.4e-183 1.1.1.1 C nadph quinone reductase
IOAFOGIE_00957 5.7e-126 hchA S DJ-1/PfpI family
IOAFOGIE_00958 1.5e-88 MA20_25245 K FR47-like protein
IOAFOGIE_00959 9.5e-153 EG EamA-like transporter family
IOAFOGIE_00960 3.4e-126 S Protein of unknown function
IOAFOGIE_00961 0.0 tetP J elongation factor G
IOAFOGIE_00962 7.9e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IOAFOGIE_00963 5.5e-172 yobV1 K WYL domain
IOAFOGIE_00964 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
IOAFOGIE_00965 1.9e-80 6.3.3.2 S ASCH
IOAFOGIE_00966 2.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
IOAFOGIE_00967 7.5e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
IOAFOGIE_00968 2.8e-249 yjjP S Putative threonine/serine exporter
IOAFOGIE_00969 5.7e-194 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOAFOGIE_00970 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IOAFOGIE_00971 1.9e-289 QT PucR C-terminal helix-turn-helix domain
IOAFOGIE_00972 1.3e-122 drgA C Nitroreductase family
IOAFOGIE_00973 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
IOAFOGIE_00974 2.3e-164 ptlF S KR domain
IOAFOGIE_00975 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOAFOGIE_00976 1e-72 C FMN binding
IOAFOGIE_00977 2.2e-157 K LysR family
IOAFOGIE_00978 2.2e-249 P Sodium:sulfate symporter transmembrane region
IOAFOGIE_00979 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
IOAFOGIE_00980 2e-115 S Elongation factor G-binding protein, N-terminal
IOAFOGIE_00981 7.6e-64 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
IOAFOGIE_00982 2.2e-119 pnb C nitroreductase
IOAFOGIE_00983 1.1e-91 ung2 3.2.2.27 L Uracil-DNA glycosylase
IOAFOGIE_00984 2.4e-85 S membrane transporter protein
IOAFOGIE_00985 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOAFOGIE_00986 6.8e-173 htrA 3.4.21.107 O serine protease
IOAFOGIE_00987 8.9e-158 vicX 3.1.26.11 S domain protein
IOAFOGIE_00988 2.9e-151 yycI S YycH protein
IOAFOGIE_00989 1.2e-244 yycH S YycH protein
IOAFOGIE_00990 0.0 vicK 2.7.13.3 T Histidine kinase
IOAFOGIE_00991 6.2e-131 K response regulator
IOAFOGIE_00993 1.7e-37
IOAFOGIE_00994 1.6e-31 cspA K Cold shock protein domain
IOAFOGIE_00995 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
IOAFOGIE_00996 2.5e-112 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
IOAFOGIE_00997 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
IOAFOGIE_00998 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IOAFOGIE_00999 4.5e-143 S haloacid dehalogenase-like hydrolase
IOAFOGIE_01001 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
IOAFOGIE_01002 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IOAFOGIE_01003 1.5e-277 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
IOAFOGIE_01004 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
IOAFOGIE_01005 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOAFOGIE_01006 4.8e-84 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOAFOGIE_01007 4e-289 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOAFOGIE_01008 1.9e-276 E ABC transporter, substratebinding protein
IOAFOGIE_01010 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IOAFOGIE_01011 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOAFOGIE_01012 8.8e-226 yttB EGP Major facilitator Superfamily
IOAFOGIE_01013 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IOAFOGIE_01014 1.4e-67 rplI J Binds to the 23S rRNA
IOAFOGIE_01015 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IOAFOGIE_01016 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOAFOGIE_01017 6.8e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IOAFOGIE_01018 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
IOAFOGIE_01019 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOAFOGIE_01020 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOAFOGIE_01021 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOAFOGIE_01022 5e-37 yaaA S S4 domain protein YaaA
IOAFOGIE_01023 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOAFOGIE_01024 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOAFOGIE_01025 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IOAFOGIE_01026 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOAFOGIE_01027 5.5e-130 jag S R3H domain protein
IOAFOGIE_01028 5.1e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IOAFOGIE_01029 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IOAFOGIE_01030 6.9e-93 S Cell surface protein
IOAFOGIE_01031 1.2e-159 S Bacterial protein of unknown function (DUF916)
IOAFOGIE_01033 7.3e-302
IOAFOGIE_01034 3.6e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IOAFOGIE_01036 1.4e-253 pepC 3.4.22.40 E aminopeptidase
IOAFOGIE_01037 2.4e-58 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
IOAFOGIE_01038 1.2e-157 degV S DegV family
IOAFOGIE_01039 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
IOAFOGIE_01040 6.7e-142 tesE Q hydratase
IOAFOGIE_01041 1.7e-104 padC Q Phenolic acid decarboxylase
IOAFOGIE_01042 3.1e-98 padR K Virulence activator alpha C-term
IOAFOGIE_01043 2.7e-79 T Universal stress protein family
IOAFOGIE_01044 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IOAFOGIE_01045 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
IOAFOGIE_01046 5.2e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOAFOGIE_01047 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IOAFOGIE_01048 2.7e-160 rbsU U ribose uptake protein RbsU
IOAFOGIE_01049 3.8e-145 IQ NAD dependent epimerase/dehydratase family
IOAFOGIE_01050 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
IOAFOGIE_01051 3.3e-86 gutM K Glucitol operon activator protein (GutM)
IOAFOGIE_01052 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
IOAFOGIE_01053 3.2e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
IOAFOGIE_01054 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IOAFOGIE_01055 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IOAFOGIE_01056 8.7e-72 K Transcriptional regulator
IOAFOGIE_01057 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IOAFOGIE_01058 1.4e-59 T EAL domain
IOAFOGIE_01059 5.6e-161 GM NmrA-like family
IOAFOGIE_01060 2.4e-221 pbuG S Permease family
IOAFOGIE_01061 7.9e-236 pbuX F xanthine permease
IOAFOGIE_01062 1e-298 pucR QT Purine catabolism regulatory protein-like family
IOAFOGIE_01063 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOAFOGIE_01064 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IOAFOGIE_01065 9.9e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOAFOGIE_01066 1.2e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IOAFOGIE_01067 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IOAFOGIE_01068 9.7e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOAFOGIE_01069 2.5e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IOAFOGIE_01070 6.2e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOAFOGIE_01071 3.5e-169 ydcZ S Putative inner membrane exporter, YdcZ
IOAFOGIE_01072 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IOAFOGIE_01073 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IOAFOGIE_01074 8.2e-96 wecD K Acetyltransferase (GNAT) family
IOAFOGIE_01075 5.6e-115 ylbE GM NAD(P)H-binding
IOAFOGIE_01076 1.9e-161 mleR K LysR family
IOAFOGIE_01077 9.5e-125 S membrane transporter protein
IOAFOGIE_01078 8.7e-18
IOAFOGIE_01079 6.6e-159 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOAFOGIE_01080 2.7e-216 patA 2.6.1.1 E Aminotransferase
IOAFOGIE_01081 7.2e-261 gabR K Bacterial regulatory proteins, gntR family
IOAFOGIE_01082 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOAFOGIE_01083 8.5e-57 S SdpI/YhfL protein family
IOAFOGIE_01084 1.8e-173 C Zinc-binding dehydrogenase
IOAFOGIE_01085 7.3e-62 K helix_turn_helix, mercury resistance
IOAFOGIE_01086 1.8e-176 yttB EGP Major facilitator Superfamily
IOAFOGIE_01087 1.1e-19 yttB EGP Major facilitator Superfamily
IOAFOGIE_01088 2.9e-269 yjcE P Sodium proton antiporter
IOAFOGIE_01089 4.9e-87 nrdI F Belongs to the NrdI family
IOAFOGIE_01090 1.2e-239 yhdP S Transporter associated domain
IOAFOGIE_01091 4.4e-58
IOAFOGIE_01092 1.6e-73 hspX O Belongs to the small heat shock protein (HSP20) family
IOAFOGIE_01093 3.8e-60
IOAFOGIE_01094 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
IOAFOGIE_01095 5.5e-138 rrp8 K LytTr DNA-binding domain
IOAFOGIE_01096 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOAFOGIE_01097 2e-138
IOAFOGIE_01098 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOAFOGIE_01099 2.4e-130 gntR2 K Transcriptional regulator
IOAFOGIE_01100 1.4e-166 S Putative esterase
IOAFOGIE_01101 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IOAFOGIE_01102 2.7e-224 lsgC M Glycosyl transferases group 1
IOAFOGIE_01103 3.3e-21 S Protein of unknown function (DUF2929)
IOAFOGIE_01104 1.7e-48 K Cro/C1-type HTH DNA-binding domain
IOAFOGIE_01105 1.6e-155 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOAFOGIE_01106 1.6e-79 uspA T universal stress protein
IOAFOGIE_01107 1.4e-206 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
IOAFOGIE_01108 3.5e-118 yugP S Putative neutral zinc metallopeptidase
IOAFOGIE_01109 4.1e-25
IOAFOGIE_01110 2.5e-145 DegV S EDD domain protein, DegV family
IOAFOGIE_01111 7.3e-127 lrgB M LrgB-like family
IOAFOGIE_01112 5.1e-64 lrgA S LrgA family
IOAFOGIE_01113 3.8e-104 J Acetyltransferase (GNAT) domain
IOAFOGIE_01114 5e-167 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
IOAFOGIE_01115 5.4e-36 S Phospholipase_D-nuclease N-terminal
IOAFOGIE_01116 2.1e-58 S Enterocin A Immunity
IOAFOGIE_01117 9.8e-88 perR P Belongs to the Fur family
IOAFOGIE_01118 2e-106
IOAFOGIE_01119 2.3e-237 S module of peptide synthetase
IOAFOGIE_01120 2e-100 S NADPH-dependent FMN reductase
IOAFOGIE_01121 8.3e-09
IOAFOGIE_01122 2.5e-126 magIII L Base excision DNA repair protein, HhH-GPD family
IOAFOGIE_01123 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
IOAFOGIE_01124 2.6e-155 1.6.5.2 GM NmrA-like family
IOAFOGIE_01125 2e-77 merR K MerR family regulatory protein
IOAFOGIE_01126 2.2e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOAFOGIE_01127 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IOAFOGIE_01128 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
IOAFOGIE_01129 2.8e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
IOAFOGIE_01130 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
IOAFOGIE_01131 3.7e-93 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IOAFOGIE_01132 3.6e-146 cof S haloacid dehalogenase-like hydrolase
IOAFOGIE_01133 1.9e-150 qorB 1.6.5.2 GM NmrA-like family
IOAFOGIE_01134 4.4e-163 K LysR substrate binding domain
IOAFOGIE_01135 1.3e-232
IOAFOGIE_01136 6.8e-242 S Neutral/alkaline non-lysosomal ceramidase, N-terminal
IOAFOGIE_01137 0.0 2.7.1.193, 2.7.1.211 G phosphotransferase system
IOAFOGIE_01138 3.9e-206 4.1.1.45 E amidohydrolase
IOAFOGIE_01139 4.7e-76
IOAFOGIE_01140 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOAFOGIE_01141 1.4e-116 ybbL S ABC transporter, ATP-binding protein
IOAFOGIE_01142 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
IOAFOGIE_01143 2.6e-205 S DUF218 domain
IOAFOGIE_01144 3.5e-180 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
IOAFOGIE_01145 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IOAFOGIE_01146 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
IOAFOGIE_01147 5e-128 S Putative adhesin
IOAFOGIE_01148 5.1e-84 XK27_06920 S Protein of unknown function (DUF1700)
IOAFOGIE_01149 6.8e-53 K Transcriptional regulator
IOAFOGIE_01150 2.9e-78 KT response to antibiotic
IOAFOGIE_01151 3.3e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IOAFOGIE_01152 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOAFOGIE_01153 8.1e-123 tcyB E ABC transporter
IOAFOGIE_01154 1.8e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IOAFOGIE_01155 5.5e-236 EK Aminotransferase, class I
IOAFOGIE_01156 2.1e-168 K LysR substrate binding domain
IOAFOGIE_01157 1.5e-147 S Alpha/beta hydrolase of unknown function (DUF915)
IOAFOGIE_01159 3.5e-247 EGP Major facilitator Superfamily
IOAFOGIE_01161 2e-07
IOAFOGIE_01162 1.7e-260 yhgE V domain protein
IOAFOGIE_01163 3.4e-109 K Transcriptional regulator (TetR family)
IOAFOGIE_01164 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
IOAFOGIE_01165 6.3e-139 endA F DNA RNA non-specific endonuclease
IOAFOGIE_01166 3.2e-103 speG J Acetyltransferase (GNAT) domain
IOAFOGIE_01167 5.7e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
IOAFOGIE_01168 4.3e-131 2.7.1.89 M Phosphotransferase enzyme family
IOAFOGIE_01169 5.3e-223 S CAAX protease self-immunity
IOAFOGIE_01170 7.1e-308 ybiT S ABC transporter, ATP-binding protein
IOAFOGIE_01171 2.8e-148 3.1.3.102, 3.1.3.104 S hydrolase
IOAFOGIE_01172 0.0 S Predicted membrane protein (DUF2207)
IOAFOGIE_01173 0.0 uvrA3 L excinuclease ABC
IOAFOGIE_01174 4.4e-209 EGP Major facilitator Superfamily
IOAFOGIE_01175 1.9e-172 ropB K Helix-turn-helix XRE-family like proteins
IOAFOGIE_01176 4.7e-176 pepR1 3.4.11.5 I Releases the N-terminal proline from various substrates
IOAFOGIE_01177 3.7e-249 puuP_1 E Amino acid permease
IOAFOGIE_01178 2.2e-233 yxiO S Vacuole effluxer Atg22 like
IOAFOGIE_01179 1.7e-256 npp S type I phosphodiesterase nucleotide pyrophosphatase
IOAFOGIE_01180 5.7e-160 I alpha/beta hydrolase fold
IOAFOGIE_01181 4.8e-131 treR K UTRA
IOAFOGIE_01182 1.6e-237
IOAFOGIE_01183 2.8e-38 S Cytochrome B5
IOAFOGIE_01184 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOAFOGIE_01185 6.2e-218 2.7.7.65 T Diguanylate cyclase, GGDEF domain
IOAFOGIE_01186 3.1e-127 yliE T EAL domain
IOAFOGIE_01187 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOAFOGIE_01188 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IOAFOGIE_01189 3.3e-80
IOAFOGIE_01190 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IOAFOGIE_01191 6.8e-192 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOAFOGIE_01192 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOAFOGIE_01193 4.9e-22
IOAFOGIE_01194 3e-67
IOAFOGIE_01195 1.2e-163 K LysR substrate binding domain
IOAFOGIE_01196 4e-243 P Sodium:sulfate symporter transmembrane region
IOAFOGIE_01197 1.5e-198 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
IOAFOGIE_01198 2.6e-101 S response to antibiotic
IOAFOGIE_01199 1.8e-137 S response to antibiotic
IOAFOGIE_01200 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IOAFOGIE_01201 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOAFOGIE_01202 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IOAFOGIE_01203 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOAFOGIE_01204 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IOAFOGIE_01205 2.7e-252 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOAFOGIE_01206 3.1e-74 yabR J RNA binding
IOAFOGIE_01207 1.1e-63 divIC D Septum formation initiator
IOAFOGIE_01209 2.2e-42 yabO J S4 domain protein
IOAFOGIE_01210 1.6e-288 yabM S Polysaccharide biosynthesis protein
IOAFOGIE_01211 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOAFOGIE_01212 4.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOAFOGIE_01213 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOAFOGIE_01214 6.4e-265 S Putative peptidoglycan binding domain
IOAFOGIE_01215 2.1e-114 S (CBS) domain
IOAFOGIE_01216 4.1e-84 S QueT transporter
IOAFOGIE_01217 9.4e-189 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOAFOGIE_01218 7.9e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine
IOAFOGIE_01219 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
IOAFOGIE_01220 1.5e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IOAFOGIE_01221 3.6e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IOAFOGIE_01222 2.2e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IOAFOGIE_01223 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IOAFOGIE_01224 5e-134 P ATPases associated with a variety of cellular activities
IOAFOGIE_01225 2.9e-129 ssuC2 U Binding-protein-dependent transport system inner membrane component
IOAFOGIE_01226 6.5e-193 P ABC transporter, substratebinding protein
IOAFOGIE_01227 2.1e-299 kup P Transport of potassium into the cell
IOAFOGIE_01228 5.7e-54 kup P Transport of potassium into the cell
IOAFOGIE_01229 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
IOAFOGIE_01230 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOAFOGIE_01231 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOAFOGIE_01232 1.5e-257 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IOAFOGIE_01233 1.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOAFOGIE_01234 2e-146
IOAFOGIE_01235 2.1e-139 htpX O Belongs to the peptidase M48B family
IOAFOGIE_01236 2.5e-90 lemA S LemA family
IOAFOGIE_01237 9.2e-127 srtA 3.4.22.70 M sortase family
IOAFOGIE_01238 3.2e-214 J translation release factor activity
IOAFOGIE_01244 5.1e-08
IOAFOGIE_01250 2.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
IOAFOGIE_01251 2.9e-59 P secondary active sulfate transmembrane transporter activity
IOAFOGIE_01252 5.1e-102 P secondary active sulfate transmembrane transporter activity
IOAFOGIE_01253 7.6e-94
IOAFOGIE_01254 2e-94 K Acetyltransferase (GNAT) domain
IOAFOGIE_01255 2.9e-156 T Calcineurin-like phosphoesterase superfamily domain
IOAFOGIE_01256 5e-114 rhaS6 K helix_turn_helix, arabinose operon control protein
IOAFOGIE_01257 1.9e-145 I Carboxylesterase family
IOAFOGIE_01258 4.3e-156 yhjX P Major Facilitator Superfamily
IOAFOGIE_01259 7.3e-113 bglK_1 GK ROK family
IOAFOGIE_01260 3.4e-231 mntH P H( )-stimulated, divalent metal cation uptake system
IOAFOGIE_01261 4.4e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IOAFOGIE_01262 5.4e-256 mmuP E amino acid
IOAFOGIE_01263 2.2e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IOAFOGIE_01264 8.7e-292 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
IOAFOGIE_01265 1.6e-121
IOAFOGIE_01266 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOAFOGIE_01267 1.4e-278 bmr3 EGP Major facilitator Superfamily
IOAFOGIE_01268 1.9e-136 N Cell shape-determining protein MreB
IOAFOGIE_01269 0.0 S Pfam Methyltransferase
IOAFOGIE_01270 2.6e-267 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
IOAFOGIE_01271 1.8e-297 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
IOAFOGIE_01272 4.2e-29
IOAFOGIE_01273 1.2e-94 ytqB 2.1.1.176 J Putative rRNA methylase
IOAFOGIE_01274 3e-124 3.6.1.27 I Acid phosphatase homologues
IOAFOGIE_01275 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOAFOGIE_01276 4.3e-300 ytgP S Polysaccharide biosynthesis protein
IOAFOGIE_01277 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IOAFOGIE_01278 6.4e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOAFOGIE_01279 1.7e-273 pepV 3.5.1.18 E dipeptidase PepV
IOAFOGIE_01280 4.1e-84 uspA T Belongs to the universal stress protein A family
IOAFOGIE_01281 1.8e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
IOAFOGIE_01282 6.4e-171 ugpA U Binding-protein-dependent transport system inner membrane component
IOAFOGIE_01283 3.6e-36 L Integrase
IOAFOGIE_01284 1e-63 K Winged helix DNA-binding domain
IOAFOGIE_01285 1.8e-181 oppF P Belongs to the ABC transporter superfamily
IOAFOGIE_01286 9.2e-203 oppD P Belongs to the ABC transporter superfamily
IOAFOGIE_01287 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOAFOGIE_01288 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOAFOGIE_01289 1.3e-309 oppA E ABC transporter, substratebinding protein
IOAFOGIE_01290 3.2e-57 ywjH S Protein of unknown function (DUF1634)
IOAFOGIE_01291 5.5e-126 yxaA S membrane transporter protein
IOAFOGIE_01292 7.1e-161 lysR5 K LysR substrate binding domain
IOAFOGIE_01293 8.5e-198 M MucBP domain
IOAFOGIE_01294 1.7e-142
IOAFOGIE_01295 7.3e-121
IOAFOGIE_01296 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IOAFOGIE_01297 3.4e-255 gor 1.8.1.7 C Glutathione reductase
IOAFOGIE_01298 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
IOAFOGIE_01299 4.6e-293 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
IOAFOGIE_01300 9.5e-213 gntP EG Gluconate
IOAFOGIE_01301 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
IOAFOGIE_01302 2.1e-187 yueF S AI-2E family transporter
IOAFOGIE_01303 8.3e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IOAFOGIE_01304 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
IOAFOGIE_01305 1e-47 K sequence-specific DNA binding
IOAFOGIE_01306 1.3e-134 cwlO M NlpC/P60 family
IOAFOGIE_01307 4.1e-106 ygaC J Belongs to the UPF0374 family
IOAFOGIE_01308 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
IOAFOGIE_01309 3.9e-125
IOAFOGIE_01310 4.4e-100 K DNA-templated transcription, initiation
IOAFOGIE_01311 2.8e-25
IOAFOGIE_01312 2e-29
IOAFOGIE_01313 7.3e-33 S Protein of unknown function (DUF2922)
IOAFOGIE_01314 1.1e-52
IOAFOGIE_01315 2.1e-120 rfbP M Bacterial sugar transferase
IOAFOGIE_01316 2.5e-240 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
IOAFOGIE_01317 6.2e-148 cps1D M Domain of unknown function (DUF4422)
IOAFOGIE_01318 9.6e-200 cps3I G Acyltransferase family
IOAFOGIE_01319 8.5e-193 cps3H
IOAFOGIE_01320 1.3e-163 cps3F
IOAFOGIE_01321 1.3e-108 cps3E
IOAFOGIE_01322 5.8e-205 cps3D
IOAFOGIE_01323 1.1e-222 glf 5.4.99.9 M UDP-galactopyranose mutase
IOAFOGIE_01324 5.2e-178 cps3B S Glycosyltransferase like family 2
IOAFOGIE_01325 2.2e-133 cps3A S Glycosyltransferase like family 2
IOAFOGIE_01326 3.4e-35 S Uncharacterized protein conserved in bacteria (DUF2247)
IOAFOGIE_01327 1.2e-41 S SMI1-KNR4 cell-wall
IOAFOGIE_01328 1.7e-81 arpU S Phage transcriptional regulator, ArpU family
IOAFOGIE_01332 8.5e-11 V HNH nucleases
IOAFOGIE_01333 2.5e-60 ps333 L Terminase small subunit
IOAFOGIE_01334 2.3e-259 S Phage terminase large subunit
IOAFOGIE_01335 4.3e-278 S Phage portal protein, SPP1 Gp6-like
IOAFOGIE_01336 4.7e-155 S Phage minor capsid protein 2
IOAFOGIE_01338 9.2e-48 S Phage minor structural protein GP20
IOAFOGIE_01339 6.4e-101
IOAFOGIE_01340 1.9e-10
IOAFOGIE_01341 2.9e-52 S Minor capsid protein
IOAFOGIE_01342 2.1e-44 S Minor capsid protein
IOAFOGIE_01343 9.8e-65 S Minor capsid protein from bacteriophage
IOAFOGIE_01344 1.9e-81
IOAFOGIE_01346 2.1e-98 S Bacteriophage Gp15 protein
IOAFOGIE_01347 0.0 S peptidoglycan catabolic process
IOAFOGIE_01348 4.3e-97 S Phage tail protein
IOAFOGIE_01349 1.6e-162 S Prophage endopeptidase tail
IOAFOGIE_01351 1.9e-36 E lipolytic protein G-D-S-L family
IOAFOGIE_01353 1.4e-153 M Glycosyl hydrolases family 25
IOAFOGIE_01354 2e-46
IOAFOGIE_01355 5.8e-26 hol S Bacteriophage holin
IOAFOGIE_01356 3.5e-26 T SpoVT / AbrB like domain
IOAFOGIE_01357 3.1e-20 chpA T Toxic component of a toxin-antitoxin (TA) module
IOAFOGIE_01358 4.6e-177 F DNA/RNA non-specific endonuclease
IOAFOGIE_01359 1.2e-38 L nuclease
IOAFOGIE_01360 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOAFOGIE_01361 2.1e-40 K Helix-turn-helix domain
IOAFOGIE_01362 2.1e-108 yvdD 3.2.2.10 S Belongs to the LOG family
IOAFOGIE_01363 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOAFOGIE_01364 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOAFOGIE_01365 6.5e-37 nrdH O Glutaredoxin
IOAFOGIE_01366 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
IOAFOGIE_01367 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOAFOGIE_01368 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOAFOGIE_01369 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IOAFOGIE_01370 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOAFOGIE_01371 2.2e-38 yaaL S Protein of unknown function (DUF2508)
IOAFOGIE_01372 1.4e-75 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOAFOGIE_01374 2.8e-48 XK27_04080 H RibD C-terminal domain
IOAFOGIE_01375 4.4e-79 K transcriptional regulator, MerR family
IOAFOGIE_01376 1.8e-74 yphH S Cupin domain
IOAFOGIE_01377 2.5e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
IOAFOGIE_01378 1.4e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IOAFOGIE_01379 4.7e-211 natB CP ABC-2 family transporter protein
IOAFOGIE_01380 1.2e-166 natA S ABC transporter, ATP-binding protein
IOAFOGIE_01382 8.9e-92 ogt 2.1.1.63 L Methyltransferase
IOAFOGIE_01383 8.6e-52 lytE M LysM domain
IOAFOGIE_01385 4.9e-266 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
IOAFOGIE_01386 1.7e-295 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
IOAFOGIE_01387 4.1e-150 rlrG K Transcriptional regulator
IOAFOGIE_01388 2.1e-172 S Conserved hypothetical protein 698
IOAFOGIE_01389 1.9e-98 rimL J Acetyltransferase (GNAT) domain
IOAFOGIE_01390 1.4e-76 S Domain of unknown function (DUF4811)
IOAFOGIE_01391 1.1e-270 lmrB EGP Major facilitator Superfamily
IOAFOGIE_01392 2.2e-189 ynfM EGP Major facilitator Superfamily
IOAFOGIE_01393 3.4e-258 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
IOAFOGIE_01394 3.6e-155 mleP3 S Membrane transport protein
IOAFOGIE_01395 9.8e-110 S Membrane
IOAFOGIE_01396 1.8e-188 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IOAFOGIE_01397 3.1e-98 1.5.1.3 H RibD C-terminal domain
IOAFOGIE_01398 1.7e-187 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
IOAFOGIE_01399 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
IOAFOGIE_01400 1.8e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IOAFOGIE_01401 1.1e-174 hrtB V ABC transporter permease
IOAFOGIE_01402 6.6e-95 S Protein of unknown function (DUF1440)
IOAFOGIE_01403 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOAFOGIE_01404 6.4e-148 KT helix_turn_helix, mercury resistance
IOAFOGIE_01405 6.6e-114 S Protein of unknown function (DUF554)
IOAFOGIE_01406 1.1e-92 yueI S Protein of unknown function (DUF1694)
IOAFOGIE_01407 1.7e-142 yvpB S Peptidase_C39 like family
IOAFOGIE_01408 6.4e-150 M Glycosyl hydrolases family 25
IOAFOGIE_01409 3.9e-111
IOAFOGIE_01410 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOAFOGIE_01411 1.8e-84 hmpT S Pfam:DUF3816
IOAFOGIE_01412 1.8e-57 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOAFOGIE_01413 1.1e-50 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOAFOGIE_01414 1.1e-40 ulaB_1 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
IOAFOGIE_01415 2e-220 ulaA 2.7.1.194 S PTS system sugar-specific permease component
IOAFOGIE_01416 2.5e-99 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
IOAFOGIE_01417 8.7e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOAFOGIE_01418 2.4e-53 yaaQ S Cyclic-di-AMP receptor
IOAFOGIE_01419 3.3e-186 holB 2.7.7.7 L DNA polymerase III
IOAFOGIE_01420 1e-57 yabA L Involved in initiation control of chromosome replication
IOAFOGIE_01421 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOAFOGIE_01422 3.6e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
IOAFOGIE_01423 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IOAFOGIE_01424 1.5e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
IOAFOGIE_01425 8.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
IOAFOGIE_01426 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
IOAFOGIE_01427 7.7e-138 phnE 3.6.1.63 U Phosphonate ABC transporter permease
IOAFOGIE_01428 6.3e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IOAFOGIE_01429 5.1e-190 phnD P Phosphonate ABC transporter
IOAFOGIE_01430 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IOAFOGIE_01431 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IOAFOGIE_01432 2.2e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IOAFOGIE_01433 5.8e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOAFOGIE_01434 2.8e-306 uup S ABC transporter, ATP-binding protein
IOAFOGIE_01435 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IOAFOGIE_01436 6.1e-109 ydiL S CAAX protease self-immunity
IOAFOGIE_01437 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOAFOGIE_01438 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOAFOGIE_01439 0.0 ydaO E amino acid
IOAFOGIE_01440 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
IOAFOGIE_01441 4.3e-145 pstS P Phosphate
IOAFOGIE_01442 1.7e-114 yvyE 3.4.13.9 S YigZ family
IOAFOGIE_01443 3.1e-256 comFA L Helicase C-terminal domain protein
IOAFOGIE_01444 7.5e-126 comFC S Competence protein
IOAFOGIE_01445 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOAFOGIE_01446 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOAFOGIE_01447 3.2e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOAFOGIE_01448 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
IOAFOGIE_01449 1.5e-132 K response regulator
IOAFOGIE_01450 3.5e-250 phoR 2.7.13.3 T Histidine kinase
IOAFOGIE_01451 1.3e-17 wcoI 2.7.10.1, 2.7.10.2 M biosynthesis protein
IOAFOGIE_01452 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IOAFOGIE_01453 1.3e-157 yihY S Belongs to the UPF0761 family
IOAFOGIE_01454 6.8e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOAFOGIE_01455 1.7e-218 pbpX1 V Beta-lactamase
IOAFOGIE_01456 1.7e-254 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IOAFOGIE_01457 5e-107
IOAFOGIE_01458 1.3e-73
IOAFOGIE_01460 1.8e-164 S Alpha/beta hydrolase of unknown function (DUF915)
IOAFOGIE_01461 4.1e-245 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOAFOGIE_01462 2.3e-75 T Universal stress protein family
IOAFOGIE_01463 5.5e-25 hol S Bacteriophage holin
IOAFOGIE_01464 5.3e-35 S Haemolysin XhlA
IOAFOGIE_01465 1.7e-202 lys M Glycosyl hydrolases family 25
IOAFOGIE_01466 6.8e-16
IOAFOGIE_01467 9.5e-77
IOAFOGIE_01470 3.6e-199
IOAFOGIE_01471 1.5e-233 S Phage minor structural protein
IOAFOGIE_01472 3e-45 S Phage minor structural protein
IOAFOGIE_01473 1.7e-225 S Phage tail protein
IOAFOGIE_01474 0.0 M Phage tail tape measure protein TP901
IOAFOGIE_01475 6.6e-24
IOAFOGIE_01476 1.7e-58 S Phage tail assembly chaperone proteins, TAC
IOAFOGIE_01477 7.4e-107 S Phage tail tube protein
IOAFOGIE_01478 7.8e-56 S Protein of unknown function (DUF806)
IOAFOGIE_01479 2.9e-64 S Bacteriophage HK97-gp10, putative tail-component
IOAFOGIE_01480 2.2e-57 S Phage head-tail joining protein
IOAFOGIE_01481 8.1e-49 S Phage gp6-like head-tail connector protein
IOAFOGIE_01482 4.3e-212 S Phage capsid family
IOAFOGIE_01483 2.1e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
IOAFOGIE_01484 1.8e-223 S Phage portal protein
IOAFOGIE_01485 5.6e-26 S Protein of unknown function (DUF1056)
IOAFOGIE_01486 0.0 S Phage Terminase
IOAFOGIE_01487 7.1e-80 S Phage terminase, small subunit
IOAFOGIE_01488 9.5e-89 L HNH nucleases
IOAFOGIE_01489 2e-07 V HNH nucleases
IOAFOGIE_01491 5.1e-35 S Transcriptional regulator, RinA family
IOAFOGIE_01492 3.7e-58 bglK_1 GK ROK family
IOAFOGIE_01493 3.7e-142 EGP Major facilitator Superfamily
IOAFOGIE_01494 2.4e-136 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
IOAFOGIE_01495 2.1e-272 XK27_00765
IOAFOGIE_01497 2e-269 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
IOAFOGIE_01498 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
IOAFOGIE_01499 5.9e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IOAFOGIE_01500 4.9e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IOAFOGIE_01501 4.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IOAFOGIE_01502 2.1e-227 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IOAFOGIE_01503 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IOAFOGIE_01504 2e-97 entB 3.5.1.19 Q Isochorismatase family
IOAFOGIE_01505 1.3e-176 1.6.5.5 C Zinc-binding dehydrogenase
IOAFOGIE_01506 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
IOAFOGIE_01507 4.4e-217 E glutamate:sodium symporter activity
IOAFOGIE_01508 1.3e-215 3.5.1.47 E Peptidase family M20/M25/M40
IOAFOGIE_01509 2.7e-199 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IOAFOGIE_01510 8.5e-60 S Protein of unknown function (DUF1648)
IOAFOGIE_01511 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IOAFOGIE_01512 3.8e-179 yneE K Transcriptional regulator
IOAFOGIE_01513 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IOAFOGIE_01514 1.1e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOAFOGIE_01515 1.3e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOAFOGIE_01516 2e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IOAFOGIE_01517 1.2e-126 IQ reductase
IOAFOGIE_01518 1.6e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOAFOGIE_01519 6.6e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IOAFOGIE_01520 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IOAFOGIE_01521 1.1e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IOAFOGIE_01522 4.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IOAFOGIE_01523 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IOAFOGIE_01524 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IOAFOGIE_01525 9.2e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
IOAFOGIE_01526 2.2e-123 S Protein of unknown function (DUF554)
IOAFOGIE_01527 8e-160 K LysR substrate binding domain
IOAFOGIE_01528 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
IOAFOGIE_01529 1.5e-192 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IOAFOGIE_01530 6.2e-94 K transcriptional regulator
IOAFOGIE_01531 1.2e-300 norB EGP Major Facilitator
IOAFOGIE_01532 1.2e-139 f42a O Band 7 protein
IOAFOGIE_01533 2.7e-85 S Protein of unknown function with HXXEE motif
IOAFOGIE_01534 8.4e-14 K Bacterial regulatory proteins, tetR family
IOAFOGIE_01535 1.1e-53
IOAFOGIE_01536 2.9e-20
IOAFOGIE_01537 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IOAFOGIE_01538 1.3e-113 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
IOAFOGIE_01539 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
IOAFOGIE_01540 7.9e-41
IOAFOGIE_01541 1.9e-67 tspO T TspO/MBR family
IOAFOGIE_01542 6.3e-76 uspA T Belongs to the universal stress protein A family
IOAFOGIE_01543 8e-66 S Protein of unknown function (DUF805)
IOAFOGIE_01544 1.8e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
IOAFOGIE_01545 3.5e-36
IOAFOGIE_01546 3.1e-14
IOAFOGIE_01547 6.5e-41 S transglycosylase associated protein
IOAFOGIE_01548 4.8e-29 S CsbD-like
IOAFOGIE_01549 9.4e-40
IOAFOGIE_01550 8.6e-281 pipD E Dipeptidase
IOAFOGIE_01551 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IOAFOGIE_01552 1.3e-254 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOAFOGIE_01553 1e-170 2.5.1.74 H UbiA prenyltransferase family
IOAFOGIE_01554 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
IOAFOGIE_01555 3.9e-50
IOAFOGIE_01556 2.4e-43
IOAFOGIE_01557 3.7e-257 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOAFOGIE_01558 1.4e-265 yfnA E Amino Acid
IOAFOGIE_01559 1.2e-149 yitU 3.1.3.104 S hydrolase
IOAFOGIE_01560 1.8e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IOAFOGIE_01561 1.7e-82 S Domain of unknown function (DUF4767)
IOAFOGIE_01562 1.3e-249 malT G Major Facilitator
IOAFOGIE_01563 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IOAFOGIE_01564 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IOAFOGIE_01565 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IOAFOGIE_01566 7.6e-205 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IOAFOGIE_01567 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IOAFOGIE_01568 3.8e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IOAFOGIE_01569 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IOAFOGIE_01570 2.1e-72 ypmB S protein conserved in bacteria
IOAFOGIE_01571 4.3e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IOAFOGIE_01572 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IOAFOGIE_01573 1.3e-128 dnaD L Replication initiation and membrane attachment
IOAFOGIE_01575 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOAFOGIE_01576 2e-99 metI P ABC transporter permease
IOAFOGIE_01577 2.7e-157 metQ_4 P Belongs to the nlpA lipoprotein family
IOAFOGIE_01578 7.6e-83 uspA T Universal stress protein family
IOAFOGIE_01579 1.6e-302 ftpA P Binding-protein-dependent transport system inner membrane component
IOAFOGIE_01580 1.1e-181 ftpB P Bacterial extracellular solute-binding protein
IOAFOGIE_01581 1.8e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
IOAFOGIE_01582 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IOAFOGIE_01583 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IOAFOGIE_01584 8.3e-110 ypsA S Belongs to the UPF0398 family
IOAFOGIE_01585 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IOAFOGIE_01587 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IOAFOGIE_01588 5.7e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
IOAFOGIE_01589 3e-243 P Major Facilitator Superfamily
IOAFOGIE_01590 1.4e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
IOAFOGIE_01591 4.4e-73 S SnoaL-like domain
IOAFOGIE_01592 1.8e-243 M Glycosyltransferase, group 2 family protein
IOAFOGIE_01593 2.5e-26 mccF V LD-carboxypeptidase
IOAFOGIE_01594 1.9e-169 mccF V LD-carboxypeptidase
IOAFOGIE_01595 1.4e-78 K Acetyltransferase (GNAT) domain
IOAFOGIE_01596 6.9e-240 M hydrolase, family 25
IOAFOGIE_01597 6.2e-182 mccF 3.4.17.13 V LD-carboxypeptidase
IOAFOGIE_01598 9.2e-125
IOAFOGIE_01599 6.6e-122 3.6.3.35 P ATPases associated with a variety of cellular activities
IOAFOGIE_01600 3.5e-194
IOAFOGIE_01601 1.5e-146 S hydrolase activity, acting on ester bonds
IOAFOGIE_01602 3.2e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
IOAFOGIE_01603 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
IOAFOGIE_01604 3.3e-62 esbA S Family of unknown function (DUF5322)
IOAFOGIE_01605 4.1e-295 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IOAFOGIE_01606 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOAFOGIE_01607 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOAFOGIE_01608 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOAFOGIE_01609 1.1e-206 carA 6.3.5.5 F Belongs to the CarA family
IOAFOGIE_01610 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IOAFOGIE_01611 4e-288 S Bacterial membrane protein, YfhO
IOAFOGIE_01612 6.4e-113 pgm5 G Phosphoglycerate mutase family
IOAFOGIE_01613 3.5e-32 frataxin S Domain of unknown function (DU1801)
IOAFOGIE_01616 1.1e-129 cat 2.3.1.28 V Chloramphenicol acetyltransferase
IOAFOGIE_01617 1.7e-46 S LuxR family transcriptional regulator
IOAFOGIE_01618 8.6e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
IOAFOGIE_01620 1.2e-91 3.6.1.55 F NUDIX domain
IOAFOGIE_01621 2.4e-164 V ABC transporter, ATP-binding protein
IOAFOGIE_01622 3.2e-37 S ABC-2 family transporter protein
IOAFOGIE_01623 3.4e-77 S ABC-2 family transporter protein
IOAFOGIE_01624 0.0 FbpA K Fibronectin-binding protein
IOAFOGIE_01625 1.9e-66 K Transcriptional regulator
IOAFOGIE_01626 7e-161 degV S EDD domain protein, DegV family
IOAFOGIE_01627 7.7e-40 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
IOAFOGIE_01628 2.9e-30 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
IOAFOGIE_01629 1.3e-131 S Protein of unknown function (DUF975)
IOAFOGIE_01630 4.3e-10
IOAFOGIE_01631 1.4e-49
IOAFOGIE_01632 3.3e-149 2.7.7.12 C Domain of unknown function (DUF4931)
IOAFOGIE_01633 8.9e-207 pmrB EGP Major facilitator Superfamily
IOAFOGIE_01634 4.6e-12
IOAFOGIE_01635 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
IOAFOGIE_01636 4.6e-129 yejC S Protein of unknown function (DUF1003)
IOAFOGIE_01637 6.1e-133 XK27_00890 S Domain of unknown function (DUF368)
IOAFOGIE_01638 2.1e-244 cycA E Amino acid permease
IOAFOGIE_01639 4.1e-116
IOAFOGIE_01640 4.1e-59
IOAFOGIE_01641 1.4e-279 lldP C L-lactate permease
IOAFOGIE_01642 2.6e-226
IOAFOGIE_01643 3.7e-128 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
IOAFOGIE_01644 1.2e-191 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
IOAFOGIE_01645 8.6e-196 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOAFOGIE_01646 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOAFOGIE_01647 8.5e-93 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
IOAFOGIE_01648 1.8e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
IOAFOGIE_01649 1.2e-239 gshR1 1.8.1.7 C Glutathione reductase
IOAFOGIE_01650 2.1e-51
IOAFOGIE_01651 9.3e-242 M Glycosyl transferase family group 2
IOAFOGIE_01652 7.5e-275 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOAFOGIE_01653 4.6e-157 xerD L Phage integrase, N-terminal SAM-like domain
IOAFOGIE_01654 4.2e-32 S YozE SAM-like fold
IOAFOGIE_01655 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOAFOGIE_01656 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IOAFOGIE_01657 1.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
IOAFOGIE_01658 1.2e-177 K Transcriptional regulator
IOAFOGIE_01659 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOAFOGIE_01660 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOAFOGIE_01661 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOAFOGIE_01662 1.1e-169 lacX 5.1.3.3 G Aldose 1-epimerase
IOAFOGIE_01663 1.5e-256 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IOAFOGIE_01664 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IOAFOGIE_01665 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
IOAFOGIE_01666 9.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IOAFOGIE_01667 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOAFOGIE_01668 4.7e-157 dprA LU DNA protecting protein DprA
IOAFOGIE_01669 3.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOAFOGIE_01670 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IOAFOGIE_01672 1.4e-228 XK27_05470 E Methionine synthase
IOAFOGIE_01673 2.3e-170 cpsY K Transcriptional regulator, LysR family
IOAFOGIE_01674 2.7e-174 L restriction endonuclease
IOAFOGIE_01675 1.1e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IOAFOGIE_01676 1.5e-197 XK27_00915 C Luciferase-like monooxygenase
IOAFOGIE_01677 9.5e-251 emrY EGP Major facilitator Superfamily
IOAFOGIE_01678 7.8e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IOAFOGIE_01679 3.4e-35 yozE S Belongs to the UPF0346 family
IOAFOGIE_01680 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
IOAFOGIE_01681 2.3e-149 ypmR E GDSL-like Lipase/Acylhydrolase
IOAFOGIE_01682 2e-147 DegV S EDD domain protein, DegV family
IOAFOGIE_01683 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IOAFOGIE_01684 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOAFOGIE_01685 0.0 yfmR S ABC transporter, ATP-binding protein
IOAFOGIE_01686 9.6e-85
IOAFOGIE_01687 2.5e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IOAFOGIE_01688 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOAFOGIE_01689 2e-149 3.1.3.102, 3.1.3.104 S hydrolase
IOAFOGIE_01690 2.1e-206 S Tetratricopeptide repeat protein
IOAFOGIE_01691 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IOAFOGIE_01692 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IOAFOGIE_01693 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
IOAFOGIE_01694 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IOAFOGIE_01695 2e-19 M Lysin motif
IOAFOGIE_01696 5.8e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
IOAFOGIE_01697 2e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
IOAFOGIE_01698 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOAFOGIE_01699 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IOAFOGIE_01700 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOAFOGIE_01701 1.4e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOAFOGIE_01702 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOAFOGIE_01703 1.1e-164 xerD D recombinase XerD
IOAFOGIE_01704 2.9e-170 cvfB S S1 domain
IOAFOGIE_01705 1.5e-74 yeaL S Protein of unknown function (DUF441)
IOAFOGIE_01706 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IOAFOGIE_01707 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IOAFOGIE_01708 0.0 dnaE 2.7.7.7 L DNA polymerase
IOAFOGIE_01709 7.3e-29 S Protein of unknown function (DUF2929)
IOAFOGIE_01710 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOAFOGIE_01711 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IOAFOGIE_01712 2.7e-196 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IOAFOGIE_01713 1.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
IOAFOGIE_01714 2.1e-219 M O-Antigen ligase
IOAFOGIE_01715 2e-119 drrB U ABC-2 type transporter
IOAFOGIE_01716 4.3e-164 drrA V ABC transporter
IOAFOGIE_01717 6.9e-84 K helix_turn_helix multiple antibiotic resistance protein
IOAFOGIE_01718 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IOAFOGIE_01719 7.8e-61 P Rhodanese Homology Domain
IOAFOGIE_01720 1.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
IOAFOGIE_01721 7.2e-184
IOAFOGIE_01722 3.6e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
IOAFOGIE_01723 4.5e-180 C Zinc-binding dehydrogenase
IOAFOGIE_01724 3.4e-250 3.6.3.6 P Cation transporter/ATPase, N-terminus
IOAFOGIE_01725 2.7e-124 3.6.3.6 P Cation transporter/ATPase, N-terminus
IOAFOGIE_01726 6.8e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOAFOGIE_01727 6.5e-241 EGP Major facilitator Superfamily
IOAFOGIE_01728 4.3e-77 K Transcriptional regulator
IOAFOGIE_01729 1.4e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IOAFOGIE_01730 1.3e-54 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IOAFOGIE_01731 3.7e-169 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IOAFOGIE_01732 1.8e-136 K DeoR C terminal sensor domain
IOAFOGIE_01733 1.2e-106 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
IOAFOGIE_01734 9.1e-71 yneH 1.20.4.1 P ArsC family
IOAFOGIE_01735 4.1e-68 S Protein of unknown function (DUF1722)
IOAFOGIE_01736 2e-112 GM epimerase
IOAFOGIE_01737 0.0 CP_1020 S Zinc finger, swim domain protein
IOAFOGIE_01738 3.7e-117 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
IOAFOGIE_01739 1.1e-75 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
IOAFOGIE_01740 6.5e-128 K Helix-turn-helix domain, rpiR family
IOAFOGIE_01741 7.7e-160 S Alpha beta hydrolase
IOAFOGIE_01742 2.2e-111 GM NmrA-like family
IOAFOGIE_01743 9.8e-79 S Uncharacterized protein conserved in bacteria (DUF2255)
IOAFOGIE_01744 2.1e-160 K Transcriptional regulator
IOAFOGIE_01745 6.7e-173 C nadph quinone reductase
IOAFOGIE_01746 1.8e-13 S Alpha beta hydrolase
IOAFOGIE_01747 2.5e-269 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IOAFOGIE_01748 1.2e-103 desR K helix_turn_helix, Lux Regulon
IOAFOGIE_01749 2.2e-204 desK 2.7.13.3 T Histidine kinase
IOAFOGIE_01750 1.3e-134 yvfS V ABC-2 type transporter
IOAFOGIE_01751 5.2e-159 yvfR V ABC transporter
IOAFOGIE_01753 6e-82 K Acetyltransferase (GNAT) domain
IOAFOGIE_01754 1.6e-79 K MarR family
IOAFOGIE_01755 3.8e-114 S Psort location CytoplasmicMembrane, score
IOAFOGIE_01756 4.7e-157 V ABC transporter, ATP-binding protein
IOAFOGIE_01757 1.1e-125 S ABC-2 family transporter protein
IOAFOGIE_01758 1.5e-124
IOAFOGIE_01759 2.9e-54
IOAFOGIE_01760 7.8e-202
IOAFOGIE_01761 1.1e-164 ytrB V ABC transporter, ATP-binding protein
IOAFOGIE_01762 3.6e-64 K helix_turn_helix gluconate operon transcriptional repressor
IOAFOGIE_01763 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOAFOGIE_01764 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOAFOGIE_01765 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IOAFOGIE_01766 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IOAFOGIE_01767 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
IOAFOGIE_01768 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOAFOGIE_01769 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IOAFOGIE_01770 6.6e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOAFOGIE_01771 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
IOAFOGIE_01772 1.3e-70 yqeY S YqeY-like protein
IOAFOGIE_01773 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IOAFOGIE_01774 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IOAFOGIE_01775 1.7e-128 C Enoyl-(Acyl carrier protein) reductase
IOAFOGIE_01776 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IOAFOGIE_01777 2.9e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOAFOGIE_01778 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOAFOGIE_01779 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOAFOGIE_01780 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IOAFOGIE_01781 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
IOAFOGIE_01782 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IOAFOGIE_01783 5.1e-164 yniA G Fructosamine kinase
IOAFOGIE_01785 8.6e-249 EGP Major facilitator Superfamily
IOAFOGIE_01786 2.8e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
IOAFOGIE_01787 4.7e-83 cvpA S Colicin V production protein
IOAFOGIE_01788 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IOAFOGIE_01789 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IOAFOGIE_01790 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
IOAFOGIE_01791 4.5e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IOAFOGIE_01792 7.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
IOAFOGIE_01793 3.4e-211 folP 2.5.1.15 H dihydropteroate synthase
IOAFOGIE_01794 6.5e-96 tag 3.2.2.20 L glycosylase
IOAFOGIE_01795 2.1e-21
IOAFOGIE_01797 4.3e-101 K Helix-turn-helix XRE-family like proteins
IOAFOGIE_01798 2.7e-160 czcD P cation diffusion facilitator family transporter
IOAFOGIE_01799 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
IOAFOGIE_01800 3e-116 hly S protein, hemolysin III
IOAFOGIE_01801 1.1e-44 qacH U Small Multidrug Resistance protein
IOAFOGIE_01802 4.4e-59 qacC P Small Multidrug Resistance protein
IOAFOGIE_01803 1.2e-216 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
IOAFOGIE_01804 6.9e-179 K AI-2E family transporter
IOAFOGIE_01805 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOAFOGIE_01806 0.0 kup P Transport of potassium into the cell
IOAFOGIE_01808 6.6e-257 yhdG E C-terminus of AA_permease
IOAFOGIE_01809 4.3e-83
IOAFOGIE_01811 8.1e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOAFOGIE_01812 5.8e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
IOAFOGIE_01813 3.5e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOAFOGIE_01814 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOAFOGIE_01815 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IOAFOGIE_01816 3.4e-55 S Enterocin A Immunity
IOAFOGIE_01817 3.1e-256 gor 1.8.1.7 C Glutathione reductase
IOAFOGIE_01818 4.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IOAFOGIE_01819 1.7e-184 D Alpha beta
IOAFOGIE_01820 7.4e-166 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
IOAFOGIE_01821 3.9e-30 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
IOAFOGIE_01822 2e-74 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOAFOGIE_01823 3.8e-148 dicA K Helix-turn-helix domain
IOAFOGIE_01824 3.2e-55
IOAFOGIE_01825 1.3e-159 T Calcineurin-like phosphoesterase superfamily domain
IOAFOGIE_01826 1.7e-63
IOAFOGIE_01827 0.0 P Concanavalin A-like lectin/glucanases superfamily
IOAFOGIE_01828 0.0 yhcA V ABC transporter, ATP-binding protein
IOAFOGIE_01829 1.2e-95 cadD P Cadmium resistance transporter
IOAFOGIE_01830 1.9e-47 K Transcriptional regulator, ArsR family
IOAFOGIE_01831 1.9e-116 S SNARE associated Golgi protein
IOAFOGIE_01832 1.1e-46
IOAFOGIE_01833 8.8e-72 T Belongs to the universal stress protein A family
IOAFOGIE_01834 8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
IOAFOGIE_01835 6.8e-36 mntH P H( )-stimulated, divalent metal cation uptake system
IOAFOGIE_01836 3.2e-121 K Helix-turn-helix XRE-family like proteins
IOAFOGIE_01837 2.8e-82 gtrA S GtrA-like protein
IOAFOGIE_01838 3.5e-114 zmp3 O Zinc-dependent metalloprotease
IOAFOGIE_01839 7e-33
IOAFOGIE_01841 5.4e-212 livJ E Receptor family ligand binding region
IOAFOGIE_01842 2.5e-128 livH U Branched-chain amino acid transport system / permease component
IOAFOGIE_01843 5.3e-141 livM E Branched-chain amino acid transport system / permease component
IOAFOGIE_01844 1.8e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
IOAFOGIE_01845 3.3e-124 livF E ABC transporter
IOAFOGIE_01846 2.4e-97 acuB S Domain in cystathionine beta-synthase and other proteins.
IOAFOGIE_01847 1e-91 S WxL domain surface cell wall-binding
IOAFOGIE_01848 2.5e-189 S Cell surface protein
IOAFOGIE_01849 8.6e-63
IOAFOGIE_01850 1e-260
IOAFOGIE_01851 3.5e-169 XK27_00670 S ABC transporter
IOAFOGIE_01852 2.3e-124 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
IOAFOGIE_01853 6.4e-117 cmpC S ATPases associated with a variety of cellular activities
IOAFOGIE_01854 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
IOAFOGIE_01855 1.3e-119 drgA C Nitroreductase family
IOAFOGIE_01856 1.1e-95 rmaB K Transcriptional regulator, MarR family
IOAFOGIE_01857 4.9e-160 lmrA 3.6.3.44 V ABC transporter
IOAFOGIE_01858 5.4e-104 K Bacterial regulatory proteins, tetR family
IOAFOGIE_01859 1.5e-49
IOAFOGIE_01860 6.9e-248 S Putative metallopeptidase domain
IOAFOGIE_01861 6e-219 3.1.3.1 S associated with various cellular activities
IOAFOGIE_01862 6.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
IOAFOGIE_01863 0.0 ubiB S ABC1 family
IOAFOGIE_01864 2.9e-249 brnQ U Component of the transport system for branched-chain amino acids
IOAFOGIE_01865 0.0 lacS G Transporter
IOAFOGIE_01866 0.0 lacA 3.2.1.23 G -beta-galactosidase
IOAFOGIE_01867 1.6e-188 lacR K Transcriptional regulator
IOAFOGIE_01868 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
IOAFOGIE_01869 7.3e-231 mdtH P Sugar (and other) transporter
IOAFOGIE_01870 5.2e-303 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
IOAFOGIE_01871 1.2e-230 EGP Major facilitator Superfamily
IOAFOGIE_01872 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
IOAFOGIE_01873 9.2e-102 fic D Fic/DOC family
IOAFOGIE_01874 1.6e-76 K Helix-turn-helix XRE-family like proteins
IOAFOGIE_01875 2e-183 galR K Transcriptional regulator
IOAFOGIE_01876 1.3e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IOAFOGIE_01877 3.1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IOAFOGIE_01878 9.3e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IOAFOGIE_01879 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IOAFOGIE_01880 2.9e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IOAFOGIE_01881 1.9e-191 rafA 3.2.1.22 G alpha-galactosidase
IOAFOGIE_01882 6.7e-237 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IOAFOGIE_01883 0.0 ylbB V ABC transporter permease
IOAFOGIE_01884 4.9e-120 macB V ABC transporter, ATP-binding protein
IOAFOGIE_01886 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOAFOGIE_01887 1.4e-99 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IOAFOGIE_01888 4.2e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IOAFOGIE_01889 1.5e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IOAFOGIE_01890 1.3e-84
IOAFOGIE_01891 9.5e-86 yvbK 3.1.3.25 K GNAT family
IOAFOGIE_01892 7e-37
IOAFOGIE_01893 1.8e-47
IOAFOGIE_01894 4.4e-112 pgm8 G Histidine phosphatase superfamily (branch 1)
IOAFOGIE_01895 1.3e-63 S Domain of unknown function (DUF4440)
IOAFOGIE_01896 1.9e-158 K LysR substrate binding domain
IOAFOGIE_01897 2.2e-50 GM NAD(P)H-binding
IOAFOGIE_01898 1.4e-41 GM NAD(P)H-binding
IOAFOGIE_01899 2.3e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IOAFOGIE_01900 5.5e-150 IQ Enoyl-(Acyl carrier protein) reductase
IOAFOGIE_01901 1.3e-34
IOAFOGIE_01902 6.1e-76 T Belongs to the universal stress protein A family
IOAFOGIE_01903 5.8e-95 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
IOAFOGIE_01904 9.9e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IOAFOGIE_01905 1.5e-81
IOAFOGIE_01906 2.5e-101 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IOAFOGIE_01907 2.5e-222 patB 4.4.1.8 E Aminotransferase, class I
IOAFOGIE_01908 8.2e-101 M Protein of unknown function (DUF3737)
IOAFOGIE_01909 1.1e-192 C Aldo/keto reductase family
IOAFOGIE_01911 0.0 mdlB V ABC transporter
IOAFOGIE_01912 0.0 mdlA V ABC transporter
IOAFOGIE_01913 1e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IOAFOGIE_01914 3.1e-206 araR K Transcriptional regulator
IOAFOGIE_01915 1.6e-255 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOAFOGIE_01916 2.5e-305 araB 2.7.1.12, 2.7.1.16, 2.7.1.5 G carbohydrate kinase FGGY
IOAFOGIE_01917 1e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IOAFOGIE_01918 1.3e-265 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IOAFOGIE_01919 6.2e-102 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
IOAFOGIE_01920 2.6e-70 yueI S Protein of unknown function (DUF1694)
IOAFOGIE_01921 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IOAFOGIE_01922 5.2e-123 K DeoR C terminal sensor domain
IOAFOGIE_01923 5.6e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOAFOGIE_01924 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IOAFOGIE_01925 1.1e-231 gatC G PTS system sugar-specific permease component
IOAFOGIE_01926 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
IOAFOGIE_01927 1.3e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
IOAFOGIE_01928 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOAFOGIE_01929 1.2e-64 L Transposase
IOAFOGIE_01930 2.8e-134 S zinc-ribbon domain
IOAFOGIE_01932 1.2e-36
IOAFOGIE_01933 8.2e-134 aroD S Alpha/beta hydrolase family
IOAFOGIE_01934 3.4e-176 S Phosphotransferase system, EIIC
IOAFOGIE_01935 1.7e-268 I acetylesterase activity
IOAFOGIE_01936 7.9e-223 sdrF M Collagen binding domain
IOAFOGIE_01937 4.8e-160 yicL EG EamA-like transporter family
IOAFOGIE_01938 1.1e-127 E lipolytic protein G-D-S-L family
IOAFOGIE_01939 3e-178 4.1.1.52 S Amidohydrolase
IOAFOGIE_01940 2.5e-112 K Transcriptional regulator C-terminal region
IOAFOGIE_01941 7.6e-46 3.6.4.12 K HxlR-like helix-turn-helix
IOAFOGIE_01942 2e-51 V COG1131 ABC-type multidrug transport system, ATPase component
IOAFOGIE_01945 8.2e-23
IOAFOGIE_01946 1.2e-15 yybN S Protein of unknown function (DUF2712)
IOAFOGIE_01947 3.3e-63 K LytTr DNA-binding domain
IOAFOGIE_01948 6.1e-65 2.7.13.3 T GHKL domain
IOAFOGIE_01949 1.1e-54 L recombinase activity
IOAFOGIE_01950 2.8e-131 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IOAFOGIE_01951 4.3e-69 S Domain of unknown function (DUF305)
IOAFOGIE_01952 6.2e-168 L Transposase
IOAFOGIE_01953 0.0 asnB 6.3.5.4 E Aluminium induced protein
IOAFOGIE_01954 1.9e-93 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IOAFOGIE_01955 0.0 L MobA MobL family protein
IOAFOGIE_01956 2.7e-26
IOAFOGIE_01957 4.7e-42
IOAFOGIE_01958 1.8e-79
IOAFOGIE_01959 1.1e-43 relB L Addiction module antitoxin, RelB DinJ family
IOAFOGIE_01960 1.8e-50 repA S Replication initiator protein A
IOAFOGIE_01962 7.8e-146 D CobQ CobB MinD ParA nucleotide binding domain protein
IOAFOGIE_01963 2.1e-58 S Family of unknown function (DUF5388)
IOAFOGIE_01964 2.3e-58 norB EGP Major Facilitator
IOAFOGIE_01966 2.2e-75 L Transposase DDE domain
IOAFOGIE_01967 7.4e-67 L Putative transposase of IS4/5 family (DUF4096)
IOAFOGIE_01968 3.8e-57 L Integrase
IOAFOGIE_01969 0.0 clpE O Belongs to the ClpA ClpB family
IOAFOGIE_01970 6.5e-30
IOAFOGIE_01971 2.7e-39 ptsH G phosphocarrier protein HPR
IOAFOGIE_01972 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOAFOGIE_01973 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IOAFOGIE_01974 4.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
IOAFOGIE_01975 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOAFOGIE_01976 4.3e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IOAFOGIE_01977 7.7e-227 patA 2.6.1.1 E Aminotransferase
IOAFOGIE_01978 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
IOAFOGIE_01979 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOAFOGIE_01980 5.7e-19 M domain protein
IOAFOGIE_01981 3.8e-73 M dTDP-4-dehydrorhamnose reductase activity
IOAFOGIE_01982 4.1e-74
IOAFOGIE_01983 1.6e-39
IOAFOGIE_01984 2.4e-38
IOAFOGIE_01985 9.6e-120 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IOAFOGIE_01986 5.3e-196 uhpT EGP Major facilitator Superfamily
IOAFOGIE_01987 3.4e-146 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
IOAFOGIE_01988 4.3e-166 K Transcriptional regulator
IOAFOGIE_01989 1.4e-150 S hydrolase
IOAFOGIE_01990 1.7e-254 brnQ U Component of the transport system for branched-chain amino acids
IOAFOGIE_01991 2.1e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IOAFOGIE_01992 6.9e-116
IOAFOGIE_01994 6.9e-17 2.7.13.3 T GHKL domain
IOAFOGIE_01995 1.2e-64 L Transposase
IOAFOGIE_01996 1.4e-201 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IOAFOGIE_01998 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
IOAFOGIE_01999 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
IOAFOGIE_02000 1.8e-12
IOAFOGIE_02001 8.7e-160 2.7.13.3 T GHKL domain
IOAFOGIE_02002 5.7e-135 K LytTr DNA-binding domain
IOAFOGIE_02003 4.9e-78 yneH 1.20.4.1 K ArsC family
IOAFOGIE_02004 4.2e-291 katA 1.11.1.6 C Belongs to the catalase family
IOAFOGIE_02005 9e-13 ytgB S Transglycosylase associated protein
IOAFOGIE_02006 3.6e-11
IOAFOGIE_02007 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
IOAFOGIE_02008 4.2e-70 S Pyrimidine dimer DNA glycosylase
IOAFOGIE_02009 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
IOAFOGIE_02011 9.6e-112 G transporter
IOAFOGIE_02012 1.2e-226 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
IOAFOGIE_02013 2.1e-58 K transcriptional regulator (AraC family)
IOAFOGIE_02014 7.5e-122 1.1.1.1 C nadph quinone reductase
IOAFOGIE_02015 5.8e-60 K Bacterial regulatory proteins, tetR family
IOAFOGIE_02016 5.3e-86
IOAFOGIE_02017 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
IOAFOGIE_02018 1.4e-50
IOAFOGIE_02019 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOAFOGIE_02020 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IOAFOGIE_02021 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOAFOGIE_02022 2.6e-39 ylqC S Belongs to the UPF0109 family
IOAFOGIE_02023 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IOAFOGIE_02024 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOAFOGIE_02025 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IOAFOGIE_02026 6.6e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOAFOGIE_02027 0.0 smc D Required for chromosome condensation and partitioning
IOAFOGIE_02028 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOAFOGIE_02029 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOAFOGIE_02030 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IOAFOGIE_02031 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IOAFOGIE_02032 0.0 yloV S DAK2 domain fusion protein YloV
IOAFOGIE_02033 1.8e-57 asp S Asp23 family, cell envelope-related function
IOAFOGIE_02034 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IOAFOGIE_02035 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
IOAFOGIE_02036 2.8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IOAFOGIE_02037 3.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IOAFOGIE_02038 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IOAFOGIE_02039 1.7e-134 stp 3.1.3.16 T phosphatase
IOAFOGIE_02040 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IOAFOGIE_02041 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOAFOGIE_02042 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOAFOGIE_02043 4e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOAFOGIE_02044 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOAFOGIE_02045 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IOAFOGIE_02046 4.5e-55
IOAFOGIE_02047 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
IOAFOGIE_02048 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOAFOGIE_02049 1.2e-104 opuCB E ABC transporter permease
IOAFOGIE_02050 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
IOAFOGIE_02051 9.7e-308 recN L May be involved in recombinational repair of damaged DNA
IOAFOGIE_02052 7.4e-77 argR K Regulates arginine biosynthesis genes
IOAFOGIE_02053 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IOAFOGIE_02054 5.5e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOAFOGIE_02055 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOAFOGIE_02056 9.3e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOAFOGIE_02057 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOAFOGIE_02058 5.8e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOAFOGIE_02059 3.5e-74 yqhY S Asp23 family, cell envelope-related function
IOAFOGIE_02060 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOAFOGIE_02061 5.9e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IOAFOGIE_02062 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IOAFOGIE_02063 3.2e-53 ysxB J Cysteine protease Prp
IOAFOGIE_02064 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IOAFOGIE_02065 2.3e-89 K Transcriptional regulator
IOAFOGIE_02066 5.4e-19
IOAFOGIE_02069 1.7e-30
IOAFOGIE_02070 5.3e-56
IOAFOGIE_02071 3.1e-98 dut S Protein conserved in bacteria
IOAFOGIE_02072 4e-181
IOAFOGIE_02073 2.5e-161
IOAFOGIE_02074 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
IOAFOGIE_02075 4.6e-64 glnR K Transcriptional regulator
IOAFOGIE_02076 2.4e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOAFOGIE_02077 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
IOAFOGIE_02078 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
IOAFOGIE_02079 1.7e-67 yqhL P Rhodanese-like protein
IOAFOGIE_02080 2.4e-110 pepE 3.4.13.21 E Belongs to the peptidase S51 family
IOAFOGIE_02081 5.7e-180 glk 2.7.1.2 G Glucokinase
IOAFOGIE_02082 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
IOAFOGIE_02083 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
IOAFOGIE_02084 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IOAFOGIE_02085 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IOAFOGIE_02086 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IOAFOGIE_02087 0.0 S membrane
IOAFOGIE_02088 1.5e-54 yneR S Belongs to the HesB IscA family
IOAFOGIE_02089 4e-75 XK27_02470 K LytTr DNA-binding domain
IOAFOGIE_02090 2.8e-94 liaI S membrane
IOAFOGIE_02091 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOAFOGIE_02092 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
IOAFOGIE_02093 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IOAFOGIE_02094 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOAFOGIE_02095 1.4e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOAFOGIE_02096 7.4e-64 yodB K Transcriptional regulator, HxlR family
IOAFOGIE_02097 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOAFOGIE_02098 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOAFOGIE_02099 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IOAFOGIE_02100 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOAFOGIE_02101 1.9e-93 S SdpI/YhfL protein family
IOAFOGIE_02102 1.3e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IOAFOGIE_02103 0.0 sbcC L Putative exonuclease SbcCD, C subunit
IOAFOGIE_02104 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IOAFOGIE_02105 8e-307 arlS 2.7.13.3 T Histidine kinase
IOAFOGIE_02106 4.3e-121 K response regulator
IOAFOGIE_02107 4.2e-245 rarA L recombination factor protein RarA
IOAFOGIE_02108 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOAFOGIE_02109 2.9e-171 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOAFOGIE_02110 2.2e-89 S Peptidase propeptide and YPEB domain
IOAFOGIE_02111 1e-96 yceD S Uncharacterized ACR, COG1399
IOAFOGIE_02112 2.4e-217 ylbM S Belongs to the UPF0348 family
IOAFOGIE_02113 4.4e-140 yqeM Q Methyltransferase
IOAFOGIE_02114 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOAFOGIE_02115 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IOAFOGIE_02116 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOAFOGIE_02117 1.1e-50 yhbY J RNA-binding protein
IOAFOGIE_02118 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
IOAFOGIE_02119 1.4e-98 yqeG S HAD phosphatase, family IIIA
IOAFOGIE_02120 1.3e-79
IOAFOGIE_02121 2.7e-249 pgaC GT2 M Glycosyl transferase
IOAFOGIE_02122 1.5e-135 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
IOAFOGIE_02123 3e-62 hxlR K Transcriptional regulator, HxlR family
IOAFOGIE_02124 1.2e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IOAFOGIE_02125 1.4e-239 yrvN L AAA C-terminal domain
IOAFOGIE_02126 9.9e-57
IOAFOGIE_02127 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOAFOGIE_02128 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IOAFOGIE_02129 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOAFOGIE_02130 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOAFOGIE_02131 3.3e-172 dnaI L Primosomal protein DnaI
IOAFOGIE_02132 2.2e-249 dnaB L replication initiation and membrane attachment
IOAFOGIE_02133 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOAFOGIE_02134 2.7e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOAFOGIE_02135 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IOAFOGIE_02136 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOAFOGIE_02137 2.2e-120 ybhL S Belongs to the BI1 family
IOAFOGIE_02138 4.9e-28 yozG K Transcriptional regulator
IOAFOGIE_02139 2.8e-97 S Protein of unknown function (DUF2975)
IOAFOGIE_02140 3.4e-73
IOAFOGIE_02141 2.7e-177
IOAFOGIE_02142 2.1e-123 narI 1.7.5.1 C Nitrate reductase
IOAFOGIE_02143 2.1e-97 narJ C Nitrate reductase delta subunit
IOAFOGIE_02144 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
IOAFOGIE_02145 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOAFOGIE_02146 8e-196 moeB 2.7.7.73, 2.7.7.80 H ThiF family
IOAFOGIE_02147 3.2e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IOAFOGIE_02148 8.2e-232 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
IOAFOGIE_02149 1.8e-89 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
IOAFOGIE_02150 1.2e-83 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IOAFOGIE_02151 2.9e-99 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IOAFOGIE_02152 7.8e-39
IOAFOGIE_02153 1.3e-75 ptsP 2.7.13.3, 2.7.3.9 T phosphoenolpyruvate-protein phosphotransferase activity
IOAFOGIE_02154 3.5e-191 comP 2.7.13.3 F Sensor histidine kinase
IOAFOGIE_02155 6.1e-117 nreC K PFAM regulatory protein LuxR
IOAFOGIE_02156 1.5e-49
IOAFOGIE_02157 4.8e-182
IOAFOGIE_02158 2.3e-159 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
IOAFOGIE_02159 6.2e-157 hipB K Helix-turn-helix
IOAFOGIE_02160 8.8e-59 yitW S Iron-sulfur cluster assembly protein
IOAFOGIE_02161 2.5e-217 narK P Transporter, major facilitator family protein
IOAFOGIE_02162 4.5e-196 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IOAFOGIE_02163 5.4e-34 moaD 2.8.1.12 H ThiS family
IOAFOGIE_02164 4.5e-70 moaE 2.8.1.12 H MoaE protein
IOAFOGIE_02165 5.8e-82 fld C NrdI Flavodoxin like
IOAFOGIE_02166 2.2e-166 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOAFOGIE_02167 9.7e-138 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
IOAFOGIE_02168 8.4e-172 fecB P Periplasmic binding protein
IOAFOGIE_02169 4.2e-272 sufB O assembly protein SufB
IOAFOGIE_02170 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
IOAFOGIE_02171 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOAFOGIE_02172 1e-243 sufD O FeS assembly protein SufD
IOAFOGIE_02173 4.2e-144 sufC O FeS assembly ATPase SufC
IOAFOGIE_02174 1.3e-34 feoA P FeoA domain
IOAFOGIE_02175 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IOAFOGIE_02176 1.3e-20 S Virus attachment protein p12 family
IOAFOGIE_02177 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IOAFOGIE_02178 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IOAFOGIE_02179 5.3e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOAFOGIE_02180 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
IOAFOGIE_02181 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOAFOGIE_02182 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
IOAFOGIE_02183 2.4e-223 ecsB U ABC transporter
IOAFOGIE_02184 1.6e-134 ecsA V ABC transporter, ATP-binding protein
IOAFOGIE_02185 9.9e-82 hit FG histidine triad
IOAFOGIE_02186 2e-42
IOAFOGIE_02187 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOAFOGIE_02188 3.5e-78 S WxL domain surface cell wall-binding
IOAFOGIE_02189 5.2e-103 S WxL domain surface cell wall-binding
IOAFOGIE_02190 1.4e-192 S Fn3-like domain
IOAFOGIE_02191 2.7e-61
IOAFOGIE_02192 0.0
IOAFOGIE_02193 1.8e-240 npr 1.11.1.1 C NADH oxidase
IOAFOGIE_02194 2.8e-111 K Bacterial regulatory proteins, tetR family
IOAFOGIE_02195 1.9e-115 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
IOAFOGIE_02196 7.2e-106
IOAFOGIE_02197 3.5e-105 GBS0088 S Nucleotidyltransferase
IOAFOGIE_02198 1.8e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IOAFOGIE_02199 2e-222 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IOAFOGIE_02200 1.8e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
IOAFOGIE_02201 6.4e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IOAFOGIE_02202 0.0 S membrane
IOAFOGIE_02203 1.7e-19 S NUDIX domain
IOAFOGIE_02204 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOAFOGIE_02205 4e-184 ykoT GT2 M Glycosyl transferase family 2
IOAFOGIE_02206 1.6e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
IOAFOGIE_02207 1.7e-99
IOAFOGIE_02208 0.0 1.3.5.4 C FAD binding domain
IOAFOGIE_02209 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
IOAFOGIE_02210 1.2e-177 K LysR substrate binding domain
IOAFOGIE_02211 3.6e-182 3.4.21.102 M Peptidase family S41
IOAFOGIE_02212 8.7e-215
IOAFOGIE_02213 3.2e-186 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOAFOGIE_02214 0.0 L AAA domain
IOAFOGIE_02215 4.8e-232 yhaO L Ser Thr phosphatase family protein
IOAFOGIE_02216 1e-54 yheA S Belongs to the UPF0342 family
IOAFOGIE_02217 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IOAFOGIE_02218 2.9e-12
IOAFOGIE_02219 4.4e-77 argR K Regulates arginine biosynthesis genes
IOAFOGIE_02220 3.2e-214 arcT 2.6.1.1 E Aminotransferase
IOAFOGIE_02221 9.8e-101 argO S LysE type translocator
IOAFOGIE_02222 8.4e-284 ydfD K Alanine-glyoxylate amino-transferase
IOAFOGIE_02223 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOAFOGIE_02224 2e-114 M ErfK YbiS YcfS YnhG
IOAFOGIE_02225 8.1e-157 EGP Major facilitator Superfamily
IOAFOGIE_02226 3.3e-38 EGP Major facilitator Superfamily
IOAFOGIE_02227 2.9e-106
IOAFOGIE_02228 0.0 yhcA V MacB-like periplasmic core domain
IOAFOGIE_02229 2.7e-82
IOAFOGIE_02230 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IOAFOGIE_02231 2.9e-78 elaA S Acetyltransferase (GNAT) domain
IOAFOGIE_02234 1.9e-31
IOAFOGIE_02235 2.1e-244 dinF V MatE
IOAFOGIE_02236 0.0 yfbS P Sodium:sulfate symporter transmembrane region
IOAFOGIE_02237 7.9e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
IOAFOGIE_02238 8.5e-176 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
IOAFOGIE_02239 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
IOAFOGIE_02240 1.6e-229 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
IOAFOGIE_02241 4.8e-304 S Protein conserved in bacteria
IOAFOGIE_02242 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOAFOGIE_02243 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IOAFOGIE_02244 3.6e-58 S Protein of unknown function (DUF1516)
IOAFOGIE_02245 1.9e-89 gtcA S Teichoic acid glycosylation protein
IOAFOGIE_02246 6.1e-180
IOAFOGIE_02247 3.5e-10
IOAFOGIE_02248 3.6e-57
IOAFOGIE_02251 0.0 uvrA2 L ABC transporter
IOAFOGIE_02252 2.5e-46
IOAFOGIE_02253 1e-90
IOAFOGIE_02254 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
IOAFOGIE_02255 1.5e-113 S CAAX protease self-immunity
IOAFOGIE_02256 2.5e-59
IOAFOGIE_02257 4.5e-55
IOAFOGIE_02258 1.6e-137 pltR K LytTr DNA-binding domain
IOAFOGIE_02259 3.2e-223 pltK 2.7.13.3 T GHKL domain
IOAFOGIE_02260 1.7e-108
IOAFOGIE_02261 2.9e-148 S Sucrose-6F-phosphate phosphohydrolase
IOAFOGIE_02262 4.6e-158 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IOAFOGIE_02263 3.9e-116 GM NAD(P)H-binding
IOAFOGIE_02264 1.6e-64 K helix_turn_helix, mercury resistance
IOAFOGIE_02265 3.5e-154 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOAFOGIE_02266 2e-175 K LytTr DNA-binding domain
IOAFOGIE_02267 8e-157 V ABC transporter
IOAFOGIE_02268 2.5e-127 V Transport permease protein
IOAFOGIE_02270 2.3e-179 XK27_06930 V domain protein
IOAFOGIE_02271 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOAFOGIE_02272 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
IOAFOGIE_02273 3.8e-125 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IOAFOGIE_02274 1.2e-260 ugpB G Bacterial extracellular solute-binding protein
IOAFOGIE_02275 1.3e-90 ugpE G ABC transporter permease
IOAFOGIE_02276 2.9e-39 ugpE G ABC transporter permease
IOAFOGIE_02277 9.6e-11 EGP Major Facilitator Superfamily
IOAFOGIE_02278 4.7e-168 K Transcriptional regulator, LysR family
IOAFOGIE_02279 2.1e-165 G Xylose isomerase-like TIM barrel
IOAFOGIE_02280 1e-156 IQ Enoyl-(Acyl carrier protein) reductase
IOAFOGIE_02281 1.6e-149 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IOAFOGIE_02282 1.9e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IOAFOGIE_02283 1.2e-219 ydiN EGP Major Facilitator Superfamily
IOAFOGIE_02284 2e-174 K Transcriptional regulator, LysR family
IOAFOGIE_02285 2.8e-165 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IOAFOGIE_02286 3.5e-132 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IOAFOGIE_02287 1.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOAFOGIE_02288 2.8e-238 1.3.5.4 C FAD binding domain
IOAFOGIE_02289 2.6e-61 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOAFOGIE_02290 7.3e-224 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
IOAFOGIE_02291 7.2e-100 tnp L DDE domain
IOAFOGIE_02292 8.4e-70 nrdI F NrdI Flavodoxin like
IOAFOGIE_02293 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOAFOGIE_02294 4.1e-159 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
IOAFOGIE_02295 9.4e-175 1.17.4.1 F Ribonucleotide reductase, small chain
IOAFOGIE_02296 1.2e-45 K Bacterial regulatory proteins, tetR family
IOAFOGIE_02297 3.6e-97 tnpR1 L Resolvase, N terminal domain
IOAFOGIE_02298 1.6e-90 S PAS domain
IOAFOGIE_02299 1.3e-274 macB_3 V FtsX-like permease family
IOAFOGIE_02300 9.7e-177 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IOAFOGIE_02301 7.8e-247 emrY EGP Major facilitator Superfamily
IOAFOGIE_02302 3.2e-45 ywfI S Chlorite dismutase
IOAFOGIE_02303 1.8e-20 S FRG
IOAFOGIE_02304 2.8e-220 EGP Major facilitator Superfamily
IOAFOGIE_02305 2.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOAFOGIE_02306 1.3e-14 3.3.1.1 H adenosylhomocysteinase activity
IOAFOGIE_02307 1.4e-234 rafA 3.2.1.22 G alpha-galactosidase
IOAFOGIE_02308 0.0 lacS G Transporter
IOAFOGIE_02309 4.1e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IOAFOGIE_02310 1.1e-173 galR K Transcriptional regulator
IOAFOGIE_02311 1.3e-193 C Aldo keto reductase family protein
IOAFOGIE_02312 2.4e-65 S pyridoxamine 5-phosphate
IOAFOGIE_02313 2.8e-194 1.3.5.4 C FAD binding domain
IOAFOGIE_02314 2.8e-88
IOAFOGIE_02315 2.9e-176 L Initiator Replication protein
IOAFOGIE_02316 2.5e-29
IOAFOGIE_02317 2.3e-107 L Integrase
IOAFOGIE_02318 2.4e-40 K prlF antitoxin for toxin YhaV_toxin
IOAFOGIE_02319 5.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IOAFOGIE_02320 0.0 ybfG M peptidoglycan-binding domain-containing protein
IOAFOGIE_02322 1.7e-84 dps P Belongs to the Dps family
IOAFOGIE_02323 4.2e-144 soj D AAA domain
IOAFOGIE_02324 5.2e-34
IOAFOGIE_02327 6.8e-127 tnp L DDE domain
IOAFOGIE_02328 2.6e-16
IOAFOGIE_02330 2.2e-38 sirR K Helix-turn-helix diphteria tox regulatory element
IOAFOGIE_02331 5.1e-250 mntH P H( )-stimulated, divalent metal cation uptake system
IOAFOGIE_02332 1.4e-56 T Belongs to the universal stress protein A family
IOAFOGIE_02333 1.1e-15
IOAFOGIE_02334 1.3e-11 S Transglycosylase associated protein
IOAFOGIE_02335 1.6e-73 S cog cog1302
IOAFOGIE_02336 1.9e-23 S Small integral membrane protein (DUF2273)
IOAFOGIE_02337 1.3e-91
IOAFOGIE_02338 2.4e-35 3.4.13.21 E Belongs to the peptidase S51 family
IOAFOGIE_02339 1.6e-39 L Transposase
IOAFOGIE_02340 4.4e-130 S haloacid dehalogenase-like hydrolase
IOAFOGIE_02341 7.7e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IOAFOGIE_02342 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
IOAFOGIE_02343 8e-42 S RelB antitoxin
IOAFOGIE_02344 1.6e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
IOAFOGIE_02347 2.3e-28
IOAFOGIE_02348 2e-27 S Protein of unknown function (DUF1093)
IOAFOGIE_02349 1.6e-63 K Helix-turn-helix XRE-family like proteins
IOAFOGIE_02350 1.9e-16
IOAFOGIE_02351 3e-53 L Integrase
IOAFOGIE_02352 5.2e-56 3.1.3.16 S Protein of unknown function (DUF1643)
IOAFOGIE_02353 2.1e-141 L Phage integrase SAM-like domain
IOAFOGIE_02354 3.6e-23 S Mor transcription activator family
IOAFOGIE_02355 3.1e-26
IOAFOGIE_02356 1.2e-77
IOAFOGIE_02358 6e-144 D PHP domain protein
IOAFOGIE_02359 7.6e-29
IOAFOGIE_02361 3.1e-59 L Integrase
IOAFOGIE_02362 1.2e-68
IOAFOGIE_02363 5.9e-26 K Transcriptional
IOAFOGIE_02364 2.9e-31
IOAFOGIE_02365 1.1e-154 L Initiator Replication protein
IOAFOGIE_02366 2.4e-50
IOAFOGIE_02367 7.5e-115 2.7.7.49 L Reverse transcriptase (RNA-dependent DNA polymerase)
IOAFOGIE_02368 1e-57 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
IOAFOGIE_02369 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IOAFOGIE_02370 1.1e-150 pstS P Phosphate
IOAFOGIE_02371 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
IOAFOGIE_02372 1.5e-155 pstA P Phosphate transport system permease protein PstA
IOAFOGIE_02373 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOAFOGIE_02374 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOAFOGIE_02375 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
IOAFOGIE_02376 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
IOAFOGIE_02377 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IOAFOGIE_02378 5.3e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IOAFOGIE_02379 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOAFOGIE_02380 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IOAFOGIE_02381 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IOAFOGIE_02382 1.9e-124 yliE T Putative diguanylate phosphodiesterase
IOAFOGIE_02383 3.3e-269 nox C NADH oxidase
IOAFOGIE_02384 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOAFOGIE_02385 2e-109 yviA S Protein of unknown function (DUF421)
IOAFOGIE_02386 1.1e-61 S Protein of unknown function (DUF3290)
IOAFOGIE_02387 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IOAFOGIE_02388 3.3e-132 yliE T Putative diguanylate phosphodiesterase
IOAFOGIE_02389 1.5e-68 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IOAFOGIE_02390 2.6e-163 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IOAFOGIE_02391 2.5e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IOAFOGIE_02392 9.2e-212 norA EGP Major facilitator Superfamily
IOAFOGIE_02393 1.2e-117 yfbR S HD containing hydrolase-like enzyme
IOAFOGIE_02394 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOAFOGIE_02395 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOAFOGIE_02396 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOAFOGIE_02397 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IOAFOGIE_02398 7.2e-264 argH 4.3.2.1 E argininosuccinate lyase
IOAFOGIE_02399 9.3e-87 S Short repeat of unknown function (DUF308)
IOAFOGIE_02400 1.6e-160 rapZ S Displays ATPase and GTPase activities
IOAFOGIE_02401 2.9e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IOAFOGIE_02402 3.7e-168 whiA K May be required for sporulation
IOAFOGIE_02403 4e-306 oppA E ABC transporter, substratebinding protein
IOAFOGIE_02404 1e-176 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOAFOGIE_02405 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOAFOGIE_02407 4.2e-245 rpoN K Sigma-54 factor, core binding domain
IOAFOGIE_02408 7.3e-189 cggR K Putative sugar-binding domain
IOAFOGIE_02409 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOAFOGIE_02410 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IOAFOGIE_02411 6.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOAFOGIE_02412 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOAFOGIE_02413 4.8e-133
IOAFOGIE_02414 6.6e-295 clcA P chloride
IOAFOGIE_02415 1.2e-30 secG U Preprotein translocase
IOAFOGIE_02416 8.5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
IOAFOGIE_02417 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IOAFOGIE_02418 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IOAFOGIE_02419 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
IOAFOGIE_02420 1.5e-256 glnP P ABC transporter
IOAFOGIE_02421 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOAFOGIE_02422 6.1e-105 yxjI
IOAFOGIE_02423 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
IOAFOGIE_02424 6.3e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOAFOGIE_02425 4.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IOAFOGIE_02426 1.5e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IOAFOGIE_02427 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
IOAFOGIE_02428 1.1e-100 dnaQ 2.7.7.7 L DNA polymerase III
IOAFOGIE_02429 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
IOAFOGIE_02430 2.5e-161 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
IOAFOGIE_02431 6.2e-168 murB 1.3.1.98 M Cell wall formation
IOAFOGIE_02432 0.0 yjcE P Sodium proton antiporter
IOAFOGIE_02433 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
IOAFOGIE_02434 7.1e-121 S Protein of unknown function (DUF1361)
IOAFOGIE_02435 7.8e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOAFOGIE_02436 1.6e-129 ybbR S YbbR-like protein
IOAFOGIE_02437 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOAFOGIE_02438 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOAFOGIE_02439 4.5e-123 yliE T EAL domain
IOAFOGIE_02440 7.8e-146 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
IOAFOGIE_02441 3.1e-104 K Bacterial regulatory proteins, tetR family
IOAFOGIE_02442 3.1e-71 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IOAFOGIE_02443 5.1e-104 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IOAFOGIE_02444 3.3e-52
IOAFOGIE_02445 3e-72
IOAFOGIE_02446 3e-131 1.5.1.39 C nitroreductase
IOAFOGIE_02447 4e-154 G Transmembrane secretion effector
IOAFOGIE_02448 1.7e-298 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOAFOGIE_02449 8.6e-142
IOAFOGIE_02451 1.9e-71 spxA 1.20.4.1 P ArsC family
IOAFOGIE_02452 1.5e-33
IOAFOGIE_02453 3.2e-89 V VanZ like family
IOAFOGIE_02454 6e-242 EGP Major facilitator Superfamily
IOAFOGIE_02455 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IOAFOGIE_02456 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IOAFOGIE_02457 1.8e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IOAFOGIE_02458 1.5e-152 licD M LicD family
IOAFOGIE_02459 1.3e-82 K Transcriptional regulator
IOAFOGIE_02460 1.5e-19
IOAFOGIE_02461 1.2e-225 pbuG S permease
IOAFOGIE_02462 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IOAFOGIE_02463 5.3e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IOAFOGIE_02464 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IOAFOGIE_02465 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IOAFOGIE_02466 3.5e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IOAFOGIE_02467 0.0 oatA I Acyltransferase
IOAFOGIE_02468 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IOAFOGIE_02469 5e-69 O OsmC-like protein
IOAFOGIE_02470 2.6e-46
IOAFOGIE_02471 1.1e-251 yfnA E Amino Acid
IOAFOGIE_02472 2.5e-88
IOAFOGIE_02473 1.9e-147 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IOAFOGIE_02474 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IOAFOGIE_02475 1.8e-19
IOAFOGIE_02476 6.3e-105 gmk2 2.7.4.8 F Guanylate kinase
IOAFOGIE_02477 3.7e-81 zur P Belongs to the Fur family
IOAFOGIE_02478 7.1e-12 3.2.1.14 GH18
IOAFOGIE_02479 4.9e-148
IOAFOGIE_02480 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IOAFOGIE_02481 3e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IOAFOGIE_02482 4.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOAFOGIE_02483 3.6e-41
IOAFOGIE_02485 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOAFOGIE_02486 7.8e-149 glnH ET ABC transporter substrate-binding protein
IOAFOGIE_02487 1.6e-109 gluC P ABC transporter permease
IOAFOGIE_02488 4e-108 glnP P ABC transporter permease
IOAFOGIE_02489 2.9e-125 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IOAFOGIE_02490 1.3e-81 gpG
IOAFOGIE_02491 3e-57 S Domain of unknown function (DUF4355)
IOAFOGIE_02492 8.9e-11 S Domain of unknown function (DUF4355)
IOAFOGIE_02493 5.9e-12
IOAFOGIE_02494 3.7e-241 iolT EGP Major facilitator Superfamily
IOAFOGIE_02495 2e-162 yxaB GM Polysaccharide pyruvyl transferase
IOAFOGIE_02496 5.6e-81 EGP Major facilitator Superfamily
IOAFOGIE_02497 3e-105 EGP Major facilitator Superfamily
IOAFOGIE_02498 1.9e-57
IOAFOGIE_02499 6e-31 cspA K Cold shock protein
IOAFOGIE_02500 3.8e-40
IOAFOGIE_02501 4.9e-16
IOAFOGIE_02502 2.3e-107 L Integrase
IOAFOGIE_02503 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
IOAFOGIE_02504 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IOAFOGIE_02505 4.6e-80 traA L MobA/MobL family
IOAFOGIE_02506 5.6e-43 traA L MobA MobL family protein
IOAFOGIE_02507 9e-146 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IOAFOGIE_02508 1.8e-193 glf 5.4.99.9 M UDP-galactopyranose mutase
IOAFOGIE_02509 1.6e-169 wbbI M transferase activity, transferring glycosyl groups
IOAFOGIE_02510 1.4e-45 L Transposase
IOAFOGIE_02512 2e-64 L Transposase
IOAFOGIE_02513 1.8e-85 2.5.1.74 H UbiA prenyltransferase family
IOAFOGIE_02514 3.7e-31 tnp2PF3 L manually curated
IOAFOGIE_02515 1e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
IOAFOGIE_02516 4.2e-113 papP P ABC transporter, permease protein
IOAFOGIE_02517 9.7e-113 P ABC transporter permease
IOAFOGIE_02518 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOAFOGIE_02519 9.1e-153 cjaA ET ABC transporter substrate-binding protein
IOAFOGIE_02520 3.6e-204 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOAFOGIE_02521 8.2e-82 L Helix-turn-helix domain
IOAFOGIE_02522 1.9e-277 S Psort location CytoplasmicMembrane, score
IOAFOGIE_02524 4.7e-25
IOAFOGIE_02525 0.0 mco Q Multicopper oxidase
IOAFOGIE_02526 3e-238 EGP Major Facilitator Superfamily
IOAFOGIE_02527 1.7e-47
IOAFOGIE_02528 2.3e-53 XK27_02070 S Nitroreductase
IOAFOGIE_02529 0.0 lacS G Transporter
IOAFOGIE_02530 5e-137 bgaR K helix_turn_helix, arabinose operon control protein
IOAFOGIE_02531 1.5e-42 S COG NOG38524 non supervised orthologous group
IOAFOGIE_02532 9.1e-128 S CAAX protease self-immunity
IOAFOGIE_02533 6.9e-133 plnD K LytTr DNA-binding domain
IOAFOGIE_02534 3.1e-69 2.7.13.3 T GHKL domain
IOAFOGIE_02535 1.2e-23 S Family of unknown function (DUF5388)
IOAFOGIE_02536 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
IOAFOGIE_02537 5.5e-14 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOAFOGIE_02538 1.5e-155 aatB ET ABC transporter substrate-binding protein
IOAFOGIE_02539 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOAFOGIE_02540 4.6e-109 glnP P ABC transporter permease
IOAFOGIE_02541 1.2e-146 minD D Belongs to the ParA family
IOAFOGIE_02542 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IOAFOGIE_02543 1.6e-88 mreD M rod shape-determining protein MreD
IOAFOGIE_02544 2.6e-144 mreC M Involved in formation and maintenance of cell shape
IOAFOGIE_02545 2.8e-161 mreB D cell shape determining protein MreB
IOAFOGIE_02546 1.3e-116 radC L DNA repair protein
IOAFOGIE_02547 4.7e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IOAFOGIE_02548 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOAFOGIE_02549 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IOAFOGIE_02550 7.5e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IOAFOGIE_02551 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IOAFOGIE_02552 1.6e-216 iscS2 2.8.1.7 E Aminotransferase class V
IOAFOGIE_02553 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IOAFOGIE_02554 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
IOAFOGIE_02555 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOAFOGIE_02556 5.2e-113 yktB S Belongs to the UPF0637 family
IOAFOGIE_02557 1.1e-80 yueI S Protein of unknown function (DUF1694)
IOAFOGIE_02558 7e-110 S Protein of unknown function (DUF1648)
IOAFOGIE_02559 6.6e-44 czrA K Helix-turn-helix domain
IOAFOGIE_02560 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IOAFOGIE_02561 8e-238 rarA L recombination factor protein RarA
IOAFOGIE_02562 1.5e-38
IOAFOGIE_02563 6.2e-82 usp6 T universal stress protein
IOAFOGIE_02564 1.2e-200 bla2 3.5.2.6 V Beta-lactamase enzyme family
IOAFOGIE_02565 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
IOAFOGIE_02566 5.1e-295 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IOAFOGIE_02567 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IOAFOGIE_02568 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IOAFOGIE_02569 1.6e-177 S Protein of unknown function (DUF2785)
IOAFOGIE_02570 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
IOAFOGIE_02571 2.2e-148 metQ M Belongs to the nlpA lipoprotein family
IOAFOGIE_02572 9.1e-111 metI U ABC transporter permease
IOAFOGIE_02573 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOAFOGIE_02574 3.6e-48 gcsH2 E glycine cleavage
IOAFOGIE_02575 9.3e-220 rodA D Belongs to the SEDS family
IOAFOGIE_02576 3.3e-33 S Protein of unknown function (DUF2969)
IOAFOGIE_02577 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IOAFOGIE_02578 2.7e-180 mbl D Cell shape determining protein MreB Mrl
IOAFOGIE_02579 2.1e-102 J Acetyltransferase (GNAT) domain
IOAFOGIE_02580 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOAFOGIE_02581 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IOAFOGIE_02582 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOAFOGIE_02583 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOAFOGIE_02584 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOAFOGIE_02585 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOAFOGIE_02586 3.9e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOAFOGIE_02587 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOAFOGIE_02588 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
IOAFOGIE_02589 1e-232 pyrP F Permease
IOAFOGIE_02590 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOAFOGIE_02591 1.1e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOAFOGIE_02592 2.2e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IOAFOGIE_02593 5.6e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOAFOGIE_02594 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOAFOGIE_02595 9.3e-109 tdk 2.7.1.21 F thymidine kinase
IOAFOGIE_02596 1.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
IOAFOGIE_02597 2.9e-136 cobQ S glutamine amidotransferase
IOAFOGIE_02598 9.8e-196 manA 5.3.1.8 G mannose-6-phosphate isomerase
IOAFOGIE_02599 1e-190 ampC V Beta-lactamase
IOAFOGIE_02600 1.5e-28
IOAFOGIE_02601 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IOAFOGIE_02602 1.9e-58
IOAFOGIE_02603 5.9e-124
IOAFOGIE_02604 0.0 yfiC V ABC transporter
IOAFOGIE_02605 0.0 ycfI V ABC transporter, ATP-binding protein
IOAFOGIE_02606 3.3e-65 S Protein of unknown function (DUF1093)
IOAFOGIE_02607 3.8e-135 yxkH G Polysaccharide deacetylase
IOAFOGIE_02610 8.9e-30
IOAFOGIE_02613 2.7e-61
IOAFOGIE_02614 3.1e-38 S Phage gp6-like head-tail connector protein
IOAFOGIE_02615 3.4e-275 S Caudovirus prohead serine protease
IOAFOGIE_02616 9.4e-203 S Phage portal protein
IOAFOGIE_02618 0.0 terL S overlaps another CDS with the same product name
IOAFOGIE_02619 9.4e-83 terS L overlaps another CDS with the same product name
IOAFOGIE_02620 3.1e-68 L HNH endonuclease
IOAFOGIE_02621 6.3e-49 S head-tail joining protein
IOAFOGIE_02623 7e-74
IOAFOGIE_02624 1.5e-266 S Virulence-associated protein E
IOAFOGIE_02625 3.7e-148 L DNA replication protein
IOAFOGIE_02626 1.4e-33
IOAFOGIE_02627 3.1e-10
IOAFOGIE_02629 1.4e-124 K sequence-specific DNA binding
IOAFOGIE_02630 1.9e-225 sip L Belongs to the 'phage' integrase family
IOAFOGIE_02631 2e-38
IOAFOGIE_02632 7.1e-43
IOAFOGIE_02633 7.3e-83 K MarR family
IOAFOGIE_02634 0.0 bztC D nuclear chromosome segregation
IOAFOGIE_02635 0.0 M MucBP domain
IOAFOGIE_02636 2.7e-16
IOAFOGIE_02637 7.2e-17
IOAFOGIE_02638 2.6e-14
IOAFOGIE_02639 1.1e-18
IOAFOGIE_02640 1.6e-16
IOAFOGIE_02641 1.6e-16
IOAFOGIE_02642 1.6e-16
IOAFOGIE_02643 1.9e-18
IOAFOGIE_02644 1.6e-16
IOAFOGIE_02645 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
IOAFOGIE_02646 2.9e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IOAFOGIE_02647 0.0 macB3 V ABC transporter, ATP-binding protein
IOAFOGIE_02648 6.8e-24
IOAFOGIE_02649 3.9e-259 pgi 5.3.1.9 G Belongs to the GPI family
IOAFOGIE_02650 9.7e-155 glcU U sugar transport
IOAFOGIE_02651 3.2e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
IOAFOGIE_02652 1.1e-286 yclK 2.7.13.3 T Histidine kinase
IOAFOGIE_02653 3.6e-134 K response regulator
IOAFOGIE_02654 3e-243 XK27_08635 S UPF0210 protein
IOAFOGIE_02655 2.3e-38 gcvR T Belongs to the UPF0237 family
IOAFOGIE_02656 4.5e-169 EG EamA-like transporter family
IOAFOGIE_02658 7.7e-92 S ECF-type riboflavin transporter, S component
IOAFOGIE_02659 8.6e-48
IOAFOGIE_02660 1.7e-213 yceI EGP Major facilitator Superfamily
IOAFOGIE_02661 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
IOAFOGIE_02662 3.8e-23
IOAFOGIE_02664 5.9e-160 S Alpha/beta hydrolase of unknown function (DUF915)
IOAFOGIE_02665 1.6e-171 ykfC 3.4.14.13 M NlpC/P60 family
IOAFOGIE_02666 8.6e-81 K AsnC family
IOAFOGIE_02667 2e-35
IOAFOGIE_02668 5.1e-34
IOAFOGIE_02669 1.9e-217 2.7.7.65 T diguanylate cyclase
IOAFOGIE_02670 5.8e-64 L Transposase
IOAFOGIE_02671 4.3e-86 yhbO 3.5.1.124 S Intracellular protease
IOAFOGIE_02672 2.5e-83 L Integrase core domain
IOAFOGIE_02673 1.7e-136 L Replication protein
IOAFOGIE_02674 8.8e-123 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
IOAFOGIE_02675 2.5e-10 S YopX protein
IOAFOGIE_02676 8.7e-42
IOAFOGIE_02677 1.3e-18
IOAFOGIE_02678 9.1e-24 V Beta-lactamase
IOAFOGIE_02679 3.3e-45 D protein tyrosine kinase activity
IOAFOGIE_02680 6e-75 Q Methyltransferase domain
IOAFOGIE_02681 2.5e-22 Q Methyltransferase domain
IOAFOGIE_02682 7.5e-39
IOAFOGIE_02683 4.4e-127 terC P integral membrane protein, YkoY family
IOAFOGIE_02684 1e-62 azlC E branched-chain amino acid
IOAFOGIE_02685 4.4e-35 yyaN K MerR HTH family regulatory protein
IOAFOGIE_02686 1.6e-196 tra L Transposase and inactivated derivatives, IS30 family
IOAFOGIE_02687 1.2e-64 L Transposase
IOAFOGIE_02688 4.6e-45
IOAFOGIE_02689 2.3e-99 S WxL domain surface cell wall-binding
IOAFOGIE_02690 1.5e-118 S WxL domain surface cell wall-binding
IOAFOGIE_02691 1.4e-163 S Cell surface protein
IOAFOGIE_02692 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
IOAFOGIE_02693 8.4e-262 nox C NADH oxidase
IOAFOGIE_02694 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IOAFOGIE_02695 0.0 pepO 3.4.24.71 O Peptidase family M13
IOAFOGIE_02696 4.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IOAFOGIE_02697 1.6e-32 copZ P Heavy-metal-associated domain
IOAFOGIE_02698 6.6e-96 dps P Belongs to the Dps family
IOAFOGIE_02699 1.6e-18
IOAFOGIE_02700 6.2e-39 yrkD S Metal-sensitive transcriptional repressor
IOAFOGIE_02701 3.3e-55 txlA O Thioredoxin-like domain
IOAFOGIE_02702 2.4e-141 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IOAFOGIE_02703 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
IOAFOGIE_02704 6.2e-182 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
IOAFOGIE_02705 3.5e-126 ydcF S Gram-negative-bacterium-type cell wall biogenesis
IOAFOGIE_02706 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IOAFOGIE_02707 7.2e-183 yfeX P Peroxidase
IOAFOGIE_02708 1.6e-100 K transcriptional regulator
IOAFOGIE_02709 2.6e-159 4.1.1.46 S Amidohydrolase
IOAFOGIE_02710 2.5e-52 S Uncharacterized protein conserved in bacteria (DUF2316)
IOAFOGIE_02711 9.5e-109
IOAFOGIE_02712 5.8e-12 K Cro/C1-type HTH DNA-binding domain
IOAFOGIE_02713 3.7e-65 XK27_09885 V VanZ like family
IOAFOGIE_02714 5.6e-12
IOAFOGIE_02716 4.2e-62
IOAFOGIE_02717 2.5e-53
IOAFOGIE_02718 2.5e-75 mltD CBM50 M PFAM NLP P60 protein
IOAFOGIE_02719 1.1e-283 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
IOAFOGIE_02720 1.8e-27
IOAFOGIE_02721 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
IOAFOGIE_02722 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
IOAFOGIE_02723 1.2e-88 K Winged helix DNA-binding domain
IOAFOGIE_02724 1.3e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
IOAFOGIE_02725 1.7e-129 S WxL domain surface cell wall-binding
IOAFOGIE_02726 1.5e-186 S Bacterial protein of unknown function (DUF916)
IOAFOGIE_02727 0.0
IOAFOGIE_02728 7.9e-161 ypuA S Protein of unknown function (DUF1002)
IOAFOGIE_02729 5.5e-50 yvlA
IOAFOGIE_02730 1.2e-95 K transcriptional regulator
IOAFOGIE_02731 2.7e-91 ymdB S Macro domain protein
IOAFOGIE_02732 3.2e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IOAFOGIE_02733 2e-77 S Threonine/Serine exporter, ThrE
IOAFOGIE_02734 9.2e-133 thrE S Putative threonine/serine exporter
IOAFOGIE_02735 1.8e-164 yvgN C Aldo keto reductase
IOAFOGIE_02736 3.8e-152 ywkB S Membrane transport protein
IOAFOGIE_02737 2.1e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IOAFOGIE_02738 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
IOAFOGIE_02739 4.5e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
IOAFOGIE_02740 2.4e-189 L PFAM Integrase, catalytic core
IOAFOGIE_02741 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
IOAFOGIE_02742 6.8e-181 D Alpha beta
IOAFOGIE_02743 5.9e-214 mdtG EGP Major facilitator Superfamily
IOAFOGIE_02744 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
IOAFOGIE_02745 1.2e-64 ycgX S Protein of unknown function (DUF1398)
IOAFOGIE_02746 1.1e-49
IOAFOGIE_02747 3.4e-25
IOAFOGIE_02748 3.3e-248 lmrB EGP Major facilitator Superfamily
IOAFOGIE_02749 5.9e-73 S COG NOG18757 non supervised orthologous group
IOAFOGIE_02750 7.4e-40
IOAFOGIE_02751 9.4e-74 copR K Copper transport repressor CopY TcrY
IOAFOGIE_02752 0.0 copB 3.6.3.4 P P-type ATPase
IOAFOGIE_02753 4.1e-189 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IOAFOGIE_02754 1.4e-111 S VIT family
IOAFOGIE_02755 1.8e-119 S membrane
IOAFOGIE_02756 1.6e-158 EG EamA-like transporter family
IOAFOGIE_02757 3.8e-81 elaA S GNAT family
IOAFOGIE_02758 9.6e-115 GM NmrA-like family
IOAFOGIE_02759 2.1e-14
IOAFOGIE_02760 7e-56
IOAFOGIE_02761 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
IOAFOGIE_02762 1.6e-85
IOAFOGIE_02763 1.9e-62
IOAFOGIE_02764 1e-212 mutY L A G-specific adenine glycosylase
IOAFOGIE_02765 4e-53
IOAFOGIE_02766 1.4e-65 yeaO S Protein of unknown function, DUF488
IOAFOGIE_02767 1.7e-69 spx4 1.20.4.1 P ArsC family
IOAFOGIE_02768 9.2e-66 K Winged helix DNA-binding domain
IOAFOGIE_02769 4.8e-162 azoB GM NmrA-like family
IOAFOGIE_02770 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
IOAFOGIE_02771 4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
IOAFOGIE_02772 2.6e-250 cycA E Amino acid permease
IOAFOGIE_02773 1.2e-255 nhaC C Na H antiporter NhaC
IOAFOGIE_02774 6.1e-27 3.2.2.10 S Belongs to the LOG family
IOAFOGIE_02775 1.3e-199 frlB M SIS domain
IOAFOGIE_02776 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IOAFOGIE_02777 1e-218 S Uncharacterized protein conserved in bacteria (DUF2325)
IOAFOGIE_02778 3.4e-123 yyaQ S YjbR
IOAFOGIE_02780 0.0 cadA P P-type ATPase
IOAFOGIE_02781 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
IOAFOGIE_02782 5.8e-120 E GDSL-like Lipase/Acylhydrolase family
IOAFOGIE_02783 1.4e-77
IOAFOGIE_02784 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
IOAFOGIE_02785 3.3e-97 FG HIT domain
IOAFOGIE_02786 5e-173 S Aldo keto reductase
IOAFOGIE_02787 3.3e-52 yitW S Pfam:DUF59
IOAFOGIE_02788 6.7e-161 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOAFOGIE_02789 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
IOAFOGIE_02790 5e-195 blaA6 V Beta-lactamase
IOAFOGIE_02791 6.2e-96 V VanZ like family
IOAFOGIE_02792 1.8e-96 tnpR1 L Resolvase, N terminal domain
IOAFOGIE_02793 1.6e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IOAFOGIE_02794 1.4e-175 L Integrase core domain
IOAFOGIE_02795 1e-154 L Integrase core domain
IOAFOGIE_02797 5.1e-68 L Putative transposase of IS4/5 family (DUF4096)
IOAFOGIE_02798 5.4e-77 L Transposase DDE domain
IOAFOGIE_02799 1.2e-61 L Transposase and inactivated derivatives, IS30 family
IOAFOGIE_02800 8.7e-78 L Transposase and inactivated derivatives, IS30 family
IOAFOGIE_02801 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
IOAFOGIE_02802 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
IOAFOGIE_02803 4e-60
IOAFOGIE_02804 1.7e-73
IOAFOGIE_02805 5e-82 yybC S Protein of unknown function (DUF2798)
IOAFOGIE_02806 1.8e-44
IOAFOGIE_02807 5.2e-47
IOAFOGIE_02808 4.6e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
IOAFOGIE_02809 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
IOAFOGIE_02810 2.4e-144 yjfP S Dienelactone hydrolase family
IOAFOGIE_02811 1.9e-68
IOAFOGIE_02812 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IOAFOGIE_02813 5.5e-46
IOAFOGIE_02814 6e-58
IOAFOGIE_02815 2.3e-164
IOAFOGIE_02816 1.3e-72 K Transcriptional regulator
IOAFOGIE_02817 0.0 pepF2 E Oligopeptidase F
IOAFOGIE_02818 4.5e-174 D Alpha beta
IOAFOGIE_02819 1.2e-45 S Enterocin A Immunity
IOAFOGIE_02820 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
IOAFOGIE_02821 5.1e-125 skfE V ABC transporter
IOAFOGIE_02822 2.7e-132
IOAFOGIE_02823 3.7e-107 pncA Q Isochorismatase family
IOAFOGIE_02824 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOAFOGIE_02825 0.0 yjcE P Sodium proton antiporter
IOAFOGIE_02826 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
IOAFOGIE_02827 2.7e-177 S Oxidoreductase family, NAD-binding Rossmann fold
IOAFOGIE_02828 8e-157 K Helix-turn-helix domain, rpiR family
IOAFOGIE_02829 6.4e-176 ccpB 5.1.1.1 K lacI family
IOAFOGIE_02830 4.2e-141 S Sucrose-6F-phosphate phosphohydrolase
IOAFOGIE_02831 1.5e-124 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
IOAFOGIE_02832 1.8e-178 K sugar-binding domain protein
IOAFOGIE_02833 0.0 ybiW 2.3.1.54 C Pyruvate formate lyase-like
IOAFOGIE_02834 3.7e-134 yciT K DeoR C terminal sensor domain
IOAFOGIE_02835 3.7e-156 pflC 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOAFOGIE_02836 1.5e-163 bglK_1 GK ROK family
IOAFOGIE_02837 3.7e-154 glcU U sugar transport
IOAFOGIE_02838 5e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOAFOGIE_02839 2.7e-177 iunH2 3.2.2.1 F nucleoside hydrolase
IOAFOGIE_02840 2.5e-98 drgA C Nitroreductase family
IOAFOGIE_02841 3.6e-168 S Polyphosphate kinase 2 (PPK2)
IOAFOGIE_02842 6.2e-182 3.6.4.13 S domain, Protein
IOAFOGIE_02843 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
IOAFOGIE_02844 2.3e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IOAFOGIE_02845 0.0 glpQ 3.1.4.46 C phosphodiesterase
IOAFOGIE_02846 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOAFOGIE_02847 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
IOAFOGIE_02848 6.1e-288 M domain protein
IOAFOGIE_02849 0.0 ydgH S MMPL family
IOAFOGIE_02850 5.4e-112 S Protein of unknown function (DUF1211)
IOAFOGIE_02851 3.7e-34
IOAFOGIE_02852 2.6e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOAFOGIE_02853 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOAFOGIE_02854 3.5e-13 rmeB K transcriptional regulator, MerR family
IOAFOGIE_02855 3.4e-50 S Domain of unknown function (DU1801)
IOAFOGIE_02856 7.6e-166 corA P CorA-like Mg2+ transporter protein
IOAFOGIE_02857 2.5e-214 ysaA V RDD family
IOAFOGIE_02858 1.7e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
IOAFOGIE_02859 5e-215 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IOAFOGIE_02860 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IOAFOGIE_02861 1.2e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IOAFOGIE_02862 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IOAFOGIE_02863 5.9e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IOAFOGIE_02864 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IOAFOGIE_02865 3.8e-134 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IOAFOGIE_02866 2.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IOAFOGIE_02867 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
IOAFOGIE_02868 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IOAFOGIE_02869 2.4e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IOAFOGIE_02870 4.8e-137 terC P membrane
IOAFOGIE_02871 4.2e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
IOAFOGIE_02872 7.4e-258 npr 1.11.1.1 C NADH oxidase
IOAFOGIE_02873 2.6e-138 XK27_08845 S ABC transporter, ATP-binding protein
IOAFOGIE_02874 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IOAFOGIE_02875 1.4e-176 XK27_08835 S ABC transporter
IOAFOGIE_02876 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IOAFOGIE_02877 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
IOAFOGIE_02878 1.5e-231 hom1 1.1.1.3 E Homoserine dehydrogenase
IOAFOGIE_02879 3.3e-161 degV S Uncharacterised protein, DegV family COG1307
IOAFOGIE_02880 6.2e-190 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOAFOGIE_02881 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
IOAFOGIE_02882 2.7e-39
IOAFOGIE_02883 5.8e-82 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOAFOGIE_02884 2e-106 3.2.2.20 K acetyltransferase
IOAFOGIE_02885 7.8e-296 S ABC transporter, ATP-binding protein
IOAFOGIE_02886 9.8e-34 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
IOAFOGIE_02890 2.3e-47 azlC E branched-chain amino acid
IOAFOGIE_02891 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
IOAFOGIE_02892 0.0 asnB 6.3.5.4 E Asparagine synthase
IOAFOGIE_02893 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
IOAFOGIE_02894 5.2e-281 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOAFOGIE_02895 6.1e-255 xylP2 G symporter
IOAFOGIE_02896 9e-192 nlhH_1 I alpha/beta hydrolase fold
IOAFOGIE_02897 5.6e-49
IOAFOGIE_02898 5e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IOAFOGIE_02899 5.7e-103 3.2.2.20 K FR47-like protein
IOAFOGIE_02900 3.4e-127 yibF S overlaps another CDS with the same product name
IOAFOGIE_02901 3.7e-219 yibE S overlaps another CDS with the same product name
IOAFOGIE_02902 1.6e-177
IOAFOGIE_02903 4.3e-138 S NADPH-dependent FMN reductase
IOAFOGIE_02904 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
IOAFOGIE_02905 8.4e-162 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IOAFOGIE_02906 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IOAFOGIE_02907 4.1e-32 L leucine-zipper of insertion element IS481
IOAFOGIE_02908 3.2e-40
IOAFOGIE_02909 8.6e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IOAFOGIE_02910 6.7e-278 pipD E Dipeptidase
IOAFOGIE_02911 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
IOAFOGIE_02912 1.8e-253 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IOAFOGIE_02913 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IOAFOGIE_02914 2.3e-81 rmaD K Transcriptional regulator
IOAFOGIE_02916 0.0 1.3.5.4 C FMN_bind
IOAFOGIE_02917 6.1e-171 K Transcriptional regulator
IOAFOGIE_02918 2.3e-96 K Helix-turn-helix domain
IOAFOGIE_02919 4.5e-140 K sequence-specific DNA binding
IOAFOGIE_02920 3.5e-88 S AAA domain
IOAFOGIE_02922 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
IOAFOGIE_02923 8.9e-90 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
IOAFOGIE_02924 3.7e-39 S MazG-like family
IOAFOGIE_02925 0.0 N Uncharacterized conserved protein (DUF2075)
IOAFOGIE_02926 0.0 pepN 3.4.11.2 E aminopeptidase
IOAFOGIE_02927 4.1e-101 G Glycogen debranching enzyme
IOAFOGIE_02928 3.4e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IOAFOGIE_02929 3.7e-161 yjdB S Domain of unknown function (DUF4767)
IOAFOGIE_02930 9.1e-147 Q Fumarylacetoacetate (FAA) hydrolase family
IOAFOGIE_02931 5.3e-72 asp2 S Asp23 family, cell envelope-related function
IOAFOGIE_02932 8.7e-72 asp S Asp23 family, cell envelope-related function
IOAFOGIE_02933 7.2e-23
IOAFOGIE_02934 2.6e-84
IOAFOGIE_02935 7.1e-37 S Transglycosylase associated protein
IOAFOGIE_02936 0.0 XK27_09800 I Acyltransferase family
IOAFOGIE_02937 2.2e-37 S MORN repeat
IOAFOGIE_02938 3.1e-153 S Cysteine-rich secretory protein family
IOAFOGIE_02939 3.2e-234 EGP Major facilitator Superfamily
IOAFOGIE_02940 3.8e-57 hxlR K HxlR-like helix-turn-helix
IOAFOGIE_02941 3.2e-116 XK27_07075 V CAAX protease self-immunity
IOAFOGIE_02942 0.0 L AAA domain
IOAFOGIE_02943 4.9e-63 K Helix-turn-helix XRE-family like proteins
IOAFOGIE_02944 6.2e-50
IOAFOGIE_02945 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IOAFOGIE_02946 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
IOAFOGIE_02947 5e-165 fabK 1.3.1.9 S Nitronate monooxygenase
IOAFOGIE_02948 0.0 helD 3.6.4.12 L DNA helicase
IOAFOGIE_02949 1.4e-110 dedA S SNARE associated Golgi protein
IOAFOGIE_02950 8.7e-300 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IOAFOGIE_02951 0.0 2.7.1.193, 2.7.1.211 G phosphotransferase system
IOAFOGIE_02952 9.2e-158 bglG3 K CAT RNA binding domain
IOAFOGIE_02953 1.6e-177 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
IOAFOGIE_02954 0.0 yjbQ P TrkA C-terminal domain protein
IOAFOGIE_02955 4.7e-125 pgm3 G Phosphoglycerate mutase family
IOAFOGIE_02956 5.5e-129 pgm3 G Phosphoglycerate mutase family
IOAFOGIE_02957 1.2e-26
IOAFOGIE_02958 1.3e-48 sugE U Multidrug resistance protein
IOAFOGIE_02959 2.9e-78 3.6.1.55 F NUDIX domain
IOAFOGIE_02960 1.9e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOAFOGIE_02961 1.5e-95 K Bacterial regulatory proteins, tetR family
IOAFOGIE_02962 3.8e-85 S membrane transporter protein
IOAFOGIE_02963 1.1e-209 EGP Major facilitator Superfamily
IOAFOGIE_02964 2.8e-70 K MarR family
IOAFOGIE_02965 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
IOAFOGIE_02966 5.7e-74 mgrA K helix_turn_helix multiple antibiotic resistance protein
IOAFOGIE_02967 8.3e-246 steT E amino acid
IOAFOGIE_02968 3.7e-142 G YdjC-like protein
IOAFOGIE_02969 7.9e-258 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
IOAFOGIE_02970 2.1e-154 K CAT RNA binding domain
IOAFOGIE_02971 1e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOAFOGIE_02972 8.6e-63 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IOAFOGIE_02973 8.8e-85
IOAFOGIE_02975 1.7e-142 pi346 L IstB-like ATP binding protein
IOAFOGIE_02976 2.9e-41 ybl78 L Conserved phage C-terminus (Phg_2220_C)
IOAFOGIE_02977 2.8e-120 S Putative HNHc nuclease
IOAFOGIE_02978 5.1e-95 S Protein of unknown function (DUF669)
IOAFOGIE_02979 1.5e-115 S AAA domain
IOAFOGIE_02980 5.7e-147 S Protein of unknown function (DUF1351)
IOAFOGIE_02982 3.3e-19
IOAFOGIE_02988 8.9e-64 S ORF6C domain
IOAFOGIE_02992 9.3e-29 ps115 K Helix-turn-helix XRE-family like proteins
IOAFOGIE_02993 2.3e-29 E Zn peptidase
IOAFOGIE_02994 7.9e-11 tcdC
IOAFOGIE_02998 7.5e-81 int L Belongs to the 'phage' integrase family
IOAFOGIE_03000 8.9e-240 yfmL 3.6.4.13 L DEAD DEAH box helicase
IOAFOGIE_03001 8.4e-190 mocA S Oxidoreductase
IOAFOGIE_03002 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
IOAFOGIE_03003 1.1e-62 S Domain of unknown function (DUF4828)
IOAFOGIE_03004 1.1e-144 lys M Glycosyl hydrolases family 25
IOAFOGIE_03005 2.3e-151 gntR K rpiR family
IOAFOGIE_03006 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
IOAFOGIE_03007 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOAFOGIE_03008 0.0 yfgQ P E1-E2 ATPase
IOAFOGIE_03009 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
IOAFOGIE_03010 1.4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOAFOGIE_03011 1e-190 yegS 2.7.1.107 G Lipid kinase
IOAFOGIE_03012 2.9e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOAFOGIE_03013 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOAFOGIE_03014 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOAFOGIE_03015 1.8e-196 camS S sex pheromone
IOAFOGIE_03016 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOAFOGIE_03017 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IOAFOGIE_03018 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IOAFOGIE_03019 1e-93 S UPF0316 protein
IOAFOGIE_03020 2e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOAFOGIE_03021 5.8e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
IOAFOGIE_03022 3.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
IOAFOGIE_03023 2.5e-164 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IOAFOGIE_03024 2.4e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOAFOGIE_03025 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
IOAFOGIE_03026 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IOAFOGIE_03027 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IOAFOGIE_03028 4.4e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IOAFOGIE_03029 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
IOAFOGIE_03030 2.8e-301 S Alpha beta
IOAFOGIE_03031 1.8e-23
IOAFOGIE_03032 3e-99 S ECF transporter, substrate-specific component
IOAFOGIE_03033 2.2e-252 yfnA E Amino Acid
IOAFOGIE_03034 1.4e-165 mleP S Sodium Bile acid symporter family
IOAFOGIE_03035 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IOAFOGIE_03036 7.5e-166 mleR K LysR family
IOAFOGIE_03037 1.1e-161 mleR K LysR family transcriptional regulator
IOAFOGIE_03038 1.2e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IOAFOGIE_03039 2.7e-263 frdC 1.3.5.4 C FAD binding domain
IOAFOGIE_03040 6.4e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOAFOGIE_03041 7.8e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IOAFOGIE_03042 2.7e-163 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
IOAFOGIE_03043 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
IOAFOGIE_03044 3.3e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IOAFOGIE_03045 3e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
IOAFOGIE_03046 2.9e-179 citR K sugar-binding domain protein
IOAFOGIE_03047 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
IOAFOGIE_03048 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOAFOGIE_03049 3.1e-50
IOAFOGIE_03050 1.3e-173 sitA P Belongs to the bacterial solute-binding protein 9 family
IOAFOGIE_03051 1.4e-140 mtsB U ABC 3 transport family
IOAFOGIE_03052 9.9e-132 mntB 3.6.3.35 P ABC transporter
IOAFOGIE_03053 3.6e-154 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IOAFOGIE_03054 1.9e-197 K Helix-turn-helix domain
IOAFOGIE_03055 5.5e-158 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
IOAFOGIE_03056 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
IOAFOGIE_03057 4.1e-53 yitW S Iron-sulfur cluster assembly protein
IOAFOGIE_03058 1.4e-262 P Sodium:sulfate symporter transmembrane region
IOAFOGIE_03059 1.2e-197 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IOAFOGIE_03060 1.8e-184 aroF 2.5.1.54 E DAHP synthetase I family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)