ORF_ID e_value Gene_name EC_number CAZy COGs Description
BPKNHKLE_00001 6.1e-183 fecB P Periplasmic binding protein
BPKNHKLE_00002 4.2e-272 sufB O assembly protein SufB
BPKNHKLE_00003 3.2e-83 nifU C SUF system FeS assembly protein, NifU family
BPKNHKLE_00004 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BPKNHKLE_00005 1.3e-243 sufD O FeS assembly protein SufD
BPKNHKLE_00006 8.5e-145 sufC O FeS assembly ATPase SufC
BPKNHKLE_00007 1.4e-33 feoA P FeoA domain
BPKNHKLE_00008 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
BPKNHKLE_00009 6.7e-23 S Virus attachment protein p12 family
BPKNHKLE_00010 6.4e-157 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
BPKNHKLE_00011 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
BPKNHKLE_00012 5.7e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPKNHKLE_00013 7.1e-217 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
BPKNHKLE_00014 7.4e-89 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BPKNHKLE_00015 1.5e-197 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
BPKNHKLE_00016 1.5e-161 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BPKNHKLE_00017 2.6e-21 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BPKNHKLE_00018 7.6e-13 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
BPKNHKLE_00019 6.4e-213 ydiN G Major Facilitator Superfamily
BPKNHKLE_00021 4.8e-242 dtpT U amino acid peptide transporter
BPKNHKLE_00024 5.1e-153 S Sucrose-6F-phosphate phosphohydrolase
BPKNHKLE_00025 7.2e-158 1.6.5.2 GM NAD(P)H-binding
BPKNHKLE_00026 5.5e-158 S Alpha beta hydrolase
BPKNHKLE_00027 2.7e-237 lmrB EGP Major facilitator Superfamily
BPKNHKLE_00029 0.0 S Bacterial membrane protein YfhO
BPKNHKLE_00030 6.6e-12
BPKNHKLE_00031 1.6e-49
BPKNHKLE_00032 0.0 kup P Transport of potassium into the cell
BPKNHKLE_00034 3.9e-284 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BPKNHKLE_00035 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
BPKNHKLE_00036 0.0 yjbQ P TrkA C-terminal domain protein
BPKNHKLE_00037 1.1e-275 pipD E Dipeptidase
BPKNHKLE_00038 3.4e-158 S Alpha/beta hydrolase of unknown function (DUF915)
BPKNHKLE_00039 8.8e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BPKNHKLE_00040 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BPKNHKLE_00041 1.6e-168 T Calcineurin-like phosphoesterase superfamily domain
BPKNHKLE_00042 2.1e-159 EGP Major facilitator Superfamily
BPKNHKLE_00043 3.4e-201 mdtG EGP Major facilitator Superfamily
BPKNHKLE_00044 1.3e-249 yhdP S Transporter associated domain
BPKNHKLE_00045 2.7e-11 naiP EGP Major facilitator Superfamily
BPKNHKLE_00046 5.1e-95 ps461 3.5.1.104 M hydrolase, family 25
BPKNHKLE_00047 8.8e-23 S Bacteriophage holin of superfamily 6 (Holin_LLH)
BPKNHKLE_00051 1.6e-13
BPKNHKLE_00052 1.2e-30 S GDSL-like Lipase/Acylhydrolase
BPKNHKLE_00055 3.1e-58 spoIVFA GT2,GT4 D peptidase
BPKNHKLE_00056 1.6e-141 rny D peptidase
BPKNHKLE_00057 5.9e-80 S Phage tail protein
BPKNHKLE_00058 1.8e-201 M Phage tail tape measure protein TP901
BPKNHKLE_00059 1.4e-26
BPKNHKLE_00060 9.3e-49 S Phage tail tube protein
BPKNHKLE_00061 1.8e-26
BPKNHKLE_00062 1.2e-18
BPKNHKLE_00063 1.9e-32 S Phage head-tail joining protein
BPKNHKLE_00064 1.3e-29 S Phage gp6-like head-tail connector protein
BPKNHKLE_00065 5e-122 S Phage capsid family
BPKNHKLE_00066 4.9e-78 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
BPKNHKLE_00067 4.4e-143 S portal protein
BPKNHKLE_00069 1e-267 S Phage Terminase
BPKNHKLE_00070 7.4e-40 L Phage terminase, small subunit
BPKNHKLE_00071 1.3e-33 L HNH nucleases
BPKNHKLE_00072 4.2e-29
BPKNHKLE_00080 3.2e-14
BPKNHKLE_00081 1.6e-20
BPKNHKLE_00082 1.5e-17 mazG S MazG nucleotide pyrophosphohydrolase domain
BPKNHKLE_00090 1.4e-83 Q DNA (cytosine-5-)-methyltransferase activity
BPKNHKLE_00094 6.2e-20 S HNH nucleases
BPKNHKLE_00095 1.6e-41 rusA L Endodeoxyribonuclease RusA
BPKNHKLE_00099 4.4e-10 K Cro/C1-type HTH DNA-binding domain
BPKNHKLE_00101 2.5e-43 dnaC 3.4.21.53 L IstB-like ATP binding protein
BPKNHKLE_00102 5.8e-63 ybl78 L DnaD domain protein
BPKNHKLE_00103 1.8e-71 S Putative HNHc nuclease
BPKNHKLE_00104 5.8e-29 S Single-strand binding protein family
BPKNHKLE_00105 1.4e-161 S PDDEXK-like domain of unknown function (DUF3799)
BPKNHKLE_00106 7.7e-140 S DNA metabolic process
BPKNHKLE_00110 8.9e-13 S Domain of unknown function (DUF771)
BPKNHKLE_00114 2.2e-121 S DNA binding
BPKNHKLE_00115 1.9e-17 cro K Helix-turn-helix XRE-family like proteins
BPKNHKLE_00116 2.1e-64 3.4.21.88 KT Peptidase S24-like
BPKNHKLE_00118 2.1e-101 L Belongs to the 'phage' integrase family
BPKNHKLE_00119 4.3e-195 naiP EGP Major facilitator Superfamily
BPKNHKLE_00120 1.7e-15 K LysR substrate binding domain protein
BPKNHKLE_00121 7.2e-52 K Transcriptional regulator
BPKNHKLE_00122 2.2e-215 E GDSL-like Lipase/Acylhydrolase family
BPKNHKLE_00123 2.3e-195 lplA 6.3.1.20 H Lipoate-protein ligase
BPKNHKLE_00124 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
BPKNHKLE_00125 1.4e-200 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
BPKNHKLE_00126 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
BPKNHKLE_00127 1.4e-182 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
BPKNHKLE_00128 1.1e-09 yphJ 4.1.1.44 S decarboxylase
BPKNHKLE_00129 1e-30 yphJ 4.1.1.44 S decarboxylase
BPKNHKLE_00130 2.8e-54 azlD E Branched-chain amino acid transport
BPKNHKLE_00131 2.3e-122 azlC E azaleucine resistance protein AzlC
BPKNHKLE_00132 1.9e-286 thrC 4.2.3.1 E Threonine synthase
BPKNHKLE_00133 3.5e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
BPKNHKLE_00134 8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
BPKNHKLE_00135 3.5e-99 K Acetyltransferase (GNAT) domain
BPKNHKLE_00136 5.3e-113 ylbE GM NAD(P)H-binding
BPKNHKLE_00137 1.8e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
BPKNHKLE_00138 4.5e-132 S Belongs to the UPF0246 family
BPKNHKLE_00139 1.3e-97
BPKNHKLE_00140 3e-159 degV S EDD domain protein, DegV family
BPKNHKLE_00141 0.0 FbpA K Fibronectin-binding protein
BPKNHKLE_00142 1.3e-102 P nitric oxide dioxygenase activity
BPKNHKLE_00143 2.1e-48 C Flavodoxin
BPKNHKLE_00144 1.2e-35 S Bacterial transferase hexapeptide (six repeats)
BPKNHKLE_00145 5.1e-29 akr5f 1.1.1.346 S reductase
BPKNHKLE_00146 4e-24 akr5f 1.1.1.346 S reductase
BPKNHKLE_00148 4.1e-214 I transferase activity, transferring acyl groups other than amino-acyl groups
BPKNHKLE_00150 3.6e-94 padC Q Phenolic acid decarboxylase
BPKNHKLE_00151 8.3e-99 padR K Virulence activator alpha C-term
BPKNHKLE_00152 3.4e-79 ndk 2.7.4.6 F Belongs to the NDK family
BPKNHKLE_00153 8e-42 S SNARE associated Golgi protein
BPKNHKLE_00154 1e-237 N Uncharacterized conserved protein (DUF2075)
BPKNHKLE_00155 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BPKNHKLE_00157 2.3e-254 yifK E Amino acid permease
BPKNHKLE_00159 2.7e-268 pipD E Dipeptidase
BPKNHKLE_00160 1.2e-163 endA F DNA RNA non-specific endonuclease
BPKNHKLE_00161 2.2e-165 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
BPKNHKLE_00162 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BPKNHKLE_00163 6.3e-154 S Alpha/beta hydrolase of unknown function (DUF915)
BPKNHKLE_00165 9.2e-228
BPKNHKLE_00166 1e-193 V Beta-lactamase
BPKNHKLE_00167 1.4e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
BPKNHKLE_00168 2.9e-123 S membrane transporter protein
BPKNHKLE_00169 4.7e-178 S AI-2E family transporter
BPKNHKLE_00170 7.4e-214 phbA 2.3.1.9 I Belongs to the thiolase family
BPKNHKLE_00171 4.1e-161 rssA S Phospholipase, patatin family
BPKNHKLE_00172 4.4e-169 K LysR substrate binding domain
BPKNHKLE_00173 0.0 1.3.5.4 C FAD binding domain
BPKNHKLE_00174 1.3e-73 S Domain of unknown function (DUF4352)
BPKNHKLE_00175 1.3e-112 yicL EG EamA-like transporter family
BPKNHKLE_00176 3.3e-64
BPKNHKLE_00179 1.1e-29
BPKNHKLE_00180 4.1e-68 S pyridoxamine 5-phosphate
BPKNHKLE_00181 2.8e-179 yobV1 K WYL domain
BPKNHKLE_00182 1.3e-243 XK27_08635 S UPF0210 protein
BPKNHKLE_00183 2.5e-40 gcvR T Belongs to the UPF0237 family
BPKNHKLE_00184 1.3e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
BPKNHKLE_00185 1.5e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
BPKNHKLE_00186 4.7e-207 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
BPKNHKLE_00187 1.7e-218 G Transporter, major facilitator family protein
BPKNHKLE_00188 1.3e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
BPKNHKLE_00189 5.3e-158 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BPKNHKLE_00190 5.5e-57 ydiI Q Thioesterase superfamily
BPKNHKLE_00192 2.8e-93 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
BPKNHKLE_00193 3.6e-32 higA K Helix-turn-helix XRE-family like proteins
BPKNHKLE_00194 1.1e-30 S Sugar efflux transporter for intercellular exchange
BPKNHKLE_00195 8.8e-88
BPKNHKLE_00196 1e-69 S Asp23 family, cell envelope-related function
BPKNHKLE_00197 6e-12 S Transglycosylase associated protein
BPKNHKLE_00198 3.8e-16
BPKNHKLE_00200 3.1e-33
BPKNHKLE_00201 1.7e-165 GK ROK family
BPKNHKLE_00202 1.1e-40
BPKNHKLE_00203 4.2e-80 copY K Copper transport repressor CopY TcrY
BPKNHKLE_00204 4e-125 O Bacterial dnaA protein
BPKNHKLE_00205 4.7e-219 L Integrase core domain
BPKNHKLE_00206 3.6e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
BPKNHKLE_00207 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
BPKNHKLE_00208 1.2e-263 npr 1.11.1.1 C NADH oxidase
BPKNHKLE_00209 6.1e-202 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
BPKNHKLE_00210 5.5e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPKNHKLE_00211 3.3e-85 macB_3 V FtsX-like permease family
BPKNHKLE_00212 2.9e-85 macB_3 V FtsX-like permease family
BPKNHKLE_00213 9.9e-146 ydjP I Alpha/beta hydrolase family
BPKNHKLE_00214 5.6e-256 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
BPKNHKLE_00215 1.7e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
BPKNHKLE_00216 4.2e-164 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
BPKNHKLE_00217 5.7e-46 citD C Covalent carrier of the coenzyme of citrate lyase
BPKNHKLE_00218 7.3e-197 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BPKNHKLE_00219 7.6e-211 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
BPKNHKLE_00220 7.2e-175 citR K sugar-binding domain protein
BPKNHKLE_00221 1.6e-231 P Sodium:sulfate symporter transmembrane region
BPKNHKLE_00222 1.7e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
BPKNHKLE_00223 2.4e-219 frdC 1.3.5.4 C FAD binding domain
BPKNHKLE_00224 1.4e-222 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
BPKNHKLE_00225 1.9e-91 XK27_09620 S NADPH-dependent FMN reductase
BPKNHKLE_00226 4.6e-183 XK27_09615 S reductase
BPKNHKLE_00227 4.2e-231 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
BPKNHKLE_00228 1.8e-79 mleR K LysR family
BPKNHKLE_00229 2e-50 nlhH_1 I Carboxylesterase family
BPKNHKLE_00230 3.6e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BPKNHKLE_00231 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
BPKNHKLE_00232 2.3e-195 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
BPKNHKLE_00233 2e-301 scrB 3.2.1.26 GH32 G invertase
BPKNHKLE_00234 1.9e-261 S Uncharacterized protein conserved in bacteria (DUF2252)
BPKNHKLE_00235 3.2e-164 K LysR substrate binding domain
BPKNHKLE_00236 6.8e-164 S Polyphosphate nucleotide phosphotransferase, PPK2 family
BPKNHKLE_00237 1.2e-111
BPKNHKLE_00239 6.2e-266 yjeM E Amino Acid
BPKNHKLE_00240 4.1e-147 ponA V Beta-lactamase enzyme family
BPKNHKLE_00241 5e-224 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BPKNHKLE_00242 1.3e-96
BPKNHKLE_00243 5.9e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
BPKNHKLE_00244 4.7e-108 lssY 3.6.1.27 I Acid phosphatase homologues
BPKNHKLE_00245 1.6e-54 S MazG-like family
BPKNHKLE_00246 0.0 L Helicase C-terminal domain protein
BPKNHKLE_00247 3.2e-71 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
BPKNHKLE_00248 7.7e-97 K transcriptional regulator
BPKNHKLE_00249 3.8e-166 lmrB EGP Major facilitator Superfamily
BPKNHKLE_00250 8.4e-64 lmrB EGP Major facilitator Superfamily
BPKNHKLE_00252 4.4e-49 tnp L MULE transposase domain
BPKNHKLE_00253 2.7e-216 L transposase, IS605 OrfB family
BPKNHKLE_00254 1.1e-50 L Helix-turn-helix domain
BPKNHKLE_00255 6.2e-85 L hmm pf00665
BPKNHKLE_00272 6.9e-33 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BPKNHKLE_00273 3.5e-30
BPKNHKLE_00274 1.2e-132 L hmm pf00665
BPKNHKLE_00275 1.6e-61 L Helix-turn-helix domain
BPKNHKLE_00276 3.3e-166 L PFAM Integrase catalytic region
BPKNHKLE_00277 1.1e-23 L Helix-turn-helix domain
BPKNHKLE_00278 9.2e-21 L transposase, IS605 OrfB family
BPKNHKLE_00279 1.5e-93 tdh 1.1.1.14 C Zinc-binding dehydrogenase
BPKNHKLE_00280 8.6e-259 guaD 3.5.4.3 F Amidohydrolase family
BPKNHKLE_00281 4.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
BPKNHKLE_00283 7.8e-57 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
BPKNHKLE_00284 6.2e-75 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
BPKNHKLE_00285 3.6e-49 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
BPKNHKLE_00286 1.1e-89 rmeB K transcriptional regulator, MerR family
BPKNHKLE_00287 7.2e-133 ybbM S Uncharacterised protein family (UPF0014)
BPKNHKLE_00288 6.4e-111 ybbL S ABC transporter, ATP-binding protein
BPKNHKLE_00289 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
BPKNHKLE_00290 5.9e-100 G Protein of unknown function (DUF4038)
BPKNHKLE_00291 3.7e-184 C Oxidoreductase
BPKNHKLE_00292 2.1e-89 deoR K sugar-binding domain protein
BPKNHKLE_00293 2.4e-114 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
BPKNHKLE_00294 1.1e-160 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
BPKNHKLE_00295 1.6e-195 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
BPKNHKLE_00296 3.2e-89 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BPKNHKLE_00297 5.3e-08 L PFAM Integrase catalytic
BPKNHKLE_00298 7.7e-46 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BPKNHKLE_00299 5.3e-167 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BPKNHKLE_00300 4.8e-84 csm5 L RAMP superfamily
BPKNHKLE_00301 1e-77 csm4 L CRISPR-associated RAMP protein, Csm4 family
BPKNHKLE_00302 1.6e-80 csm3 L RAMP superfamily
BPKNHKLE_00303 3.5e-19 csm2 L CRISPR-associated protein Csm2 family
BPKNHKLE_00304 2.2e-225 csm1 S CRISPR-associated protein Csm1 family
BPKNHKLE_00305 4e-51 cas6 S Pfam:DUF2276
BPKNHKLE_00306 2.2e-56 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
BPKNHKLE_00307 0.0 L Type III restriction enzyme, res subunit
BPKNHKLE_00309 2.4e-101 K DNA-templated transcription, initiation
BPKNHKLE_00310 1.4e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BPKNHKLE_00311 2.3e-30 arsD S Arsenical resistance operon trans-acting repressor ArsD
BPKNHKLE_00312 1.8e-232 arsB U Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BPKNHKLE_00313 0.0 arsA 3.6.3.16 D Anion-transporting ATPase
BPKNHKLE_00314 1.8e-56 arsR K Helix-turn-helix domain
BPKNHKLE_00315 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
BPKNHKLE_00316 3.3e-155 L COG2801 Transposase and inactivated derivatives
BPKNHKLE_00317 4.2e-116 arcD S C4-dicarboxylate anaerobic carrier
BPKNHKLE_00318 2e-22 S Phage capsid family
BPKNHKLE_00319 1.9e-134 S interspecies interaction between organisms
BPKNHKLE_00321 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
BPKNHKLE_00322 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BPKNHKLE_00323 2.2e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
BPKNHKLE_00324 1.1e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BPKNHKLE_00325 5.8e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BPKNHKLE_00326 4.6e-149 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BPKNHKLE_00327 2.8e-61 rplQ J Ribosomal protein L17
BPKNHKLE_00328 2e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BPKNHKLE_00329 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BPKNHKLE_00330 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BPKNHKLE_00331 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
BPKNHKLE_00332 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BPKNHKLE_00333 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
BPKNHKLE_00334 1e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
BPKNHKLE_00335 2.1e-65 rplO J Binds to the 23S rRNA
BPKNHKLE_00336 2.5e-23 rpmD J Ribosomal protein L30
BPKNHKLE_00337 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BPKNHKLE_00338 5.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BPKNHKLE_00339 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BPKNHKLE_00340 3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BPKNHKLE_00341 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BPKNHKLE_00342 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BPKNHKLE_00343 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BPKNHKLE_00344 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BPKNHKLE_00345 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BPKNHKLE_00346 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
BPKNHKLE_00347 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BPKNHKLE_00348 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BPKNHKLE_00349 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BPKNHKLE_00350 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BPKNHKLE_00351 3.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BPKNHKLE_00352 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
BPKNHKLE_00353 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
BPKNHKLE_00354 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BPKNHKLE_00355 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
BPKNHKLE_00356 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BPKNHKLE_00357 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
BPKNHKLE_00358 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BPKNHKLE_00359 2.1e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
BPKNHKLE_00360 3.7e-213 ykiI
BPKNHKLE_00361 5.6e-135 puuD S peptidase C26
BPKNHKLE_00362 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BPKNHKLE_00363 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BPKNHKLE_00364 5.8e-106 K Bacterial regulatory proteins, tetR family
BPKNHKLE_00365 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
BPKNHKLE_00366 4.8e-79 ctsR K Belongs to the CtsR family
BPKNHKLE_00367 9.7e-194 adhP 1.1.1.1 C alcohol dehydrogenase
BPKNHKLE_00368 1.9e-132 XK27_07210 6.1.1.6 S B3 4 domain
BPKNHKLE_00369 2.7e-120 J 2'-5' RNA ligase superfamily
BPKNHKLE_00371 7.7e-39 S ABC-type cobalt transport system, permease component
BPKNHKLE_00372 1.2e-16 S ABC-type cobalt transport system, permease component
BPKNHKLE_00373 2.2e-43 K helix_turn_helix multiple antibiotic resistance protein
BPKNHKLE_00374 6.3e-16 2.1.1.303 K DNA-binding transcription factor activity
BPKNHKLE_00377 4e-27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
BPKNHKLE_00378 1e-15
BPKNHKLE_00379 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
BPKNHKLE_00380 6.6e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
BPKNHKLE_00381 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BPKNHKLE_00382 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
BPKNHKLE_00383 1.5e-253 yifK E Amino acid permease
BPKNHKLE_00384 3.2e-289 clcA P chloride
BPKNHKLE_00385 4.5e-33 secG U Preprotein translocase
BPKNHKLE_00386 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
BPKNHKLE_00387 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
BPKNHKLE_00388 7.9e-108 yxjI
BPKNHKLE_00389 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BPKNHKLE_00390 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
BPKNHKLE_00391 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
BPKNHKLE_00392 1.6e-88 K Acetyltransferase (GNAT) domain
BPKNHKLE_00393 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
BPKNHKLE_00394 5.7e-166 murB 1.3.1.98 M Cell wall formation
BPKNHKLE_00395 7.8e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BPKNHKLE_00396 9.1e-116 ybbR S YbbR-like protein
BPKNHKLE_00397 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BPKNHKLE_00398 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
BPKNHKLE_00399 1.5e-52
BPKNHKLE_00400 1.2e-210 oatA I Acyltransferase
BPKNHKLE_00401 4e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
BPKNHKLE_00402 1.3e-68 lytE M Lysin motif
BPKNHKLE_00403 2.7e-159 MA20_14895 S Conserved hypothetical protein 698
BPKNHKLE_00404 9.6e-169 K LysR substrate binding domain
BPKNHKLE_00405 1.9e-130 manA 5.3.1.8 G mannose-6-phosphate isomerase
BPKNHKLE_00406 6.6e-148 yitS S EDD domain protein, DegV family
BPKNHKLE_00407 6.5e-90 racA K Domain of unknown function (DUF1836)
BPKNHKLE_00408 2.3e-181 yfeX P Peroxidase
BPKNHKLE_00409 4.5e-180 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
BPKNHKLE_00410 3.5e-114 manY G PTS system
BPKNHKLE_00411 3e-170 manN G system, mannose fructose sorbose family IID component
BPKNHKLE_00412 1.6e-57 S Domain of unknown function (DUF956)
BPKNHKLE_00414 2.8e-131 K response regulator
BPKNHKLE_00415 1.3e-250 yclK 2.7.13.3 T Histidine kinase
BPKNHKLE_00416 3.8e-151 glcU U sugar transport
BPKNHKLE_00419 7.1e-33 L Belongs to the 'phage' integrase family
BPKNHKLE_00422 5.3e-17 mleP3 S Membrane transport protein
BPKNHKLE_00423 9.7e-118 yplB S Ankyrin repeats (3 copies)
BPKNHKLE_00424 4.9e-103 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BPKNHKLE_00425 4.8e-86 yrjD S LUD domain
BPKNHKLE_00426 1.4e-244 lutB C 4Fe-4S dicluster domain
BPKNHKLE_00427 5.6e-122 lutA C Cysteine-rich domain
BPKNHKLE_00428 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
BPKNHKLE_00429 4.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BPKNHKLE_00430 2.4e-37 ynzC S UPF0291 protein
BPKNHKLE_00431 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
BPKNHKLE_00432 3.3e-115 plsC 2.3.1.51 I Acyltransferase
BPKNHKLE_00433 8e-137 yabB 2.1.1.223 L Methyltransferase small domain
BPKNHKLE_00434 2.3e-47 yazA L GIY-YIG catalytic domain protein
BPKNHKLE_00435 5e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
BPKNHKLE_00436 4.9e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BPKNHKLE_00437 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
BPKNHKLE_00438 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
BPKNHKLE_00439 5.9e-143 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BPKNHKLE_00440 2.3e-134 cdsA 2.7.7.41 I Belongs to the CDS family
BPKNHKLE_00441 1.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
BPKNHKLE_00442 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
BPKNHKLE_00443 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BPKNHKLE_00444 4.1e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
BPKNHKLE_00445 2.7e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
BPKNHKLE_00446 2.6e-206 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BPKNHKLE_00447 1.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BPKNHKLE_00448 4.7e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
BPKNHKLE_00449 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
BPKNHKLE_00450 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
BPKNHKLE_00451 8.3e-224 nusA K Participates in both transcription termination and antitermination
BPKNHKLE_00452 2.4e-47 ylxR K Protein of unknown function (DUF448)
BPKNHKLE_00453 1.6e-49 ylxQ J ribosomal protein
BPKNHKLE_00454 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BPKNHKLE_00455 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BPKNHKLE_00456 5.7e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BPKNHKLE_00457 5e-184 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
BPKNHKLE_00458 1.1e-248 EGP Major facilitator Superfamily
BPKNHKLE_00459 3.6e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
BPKNHKLE_00461 3e-72 ybeZ T Phosphate starvation-inducible protein PhoH
BPKNHKLE_00462 1e-56 trxA1 O Belongs to the thioredoxin family
BPKNHKLE_00463 2.3e-142 terC P membrane
BPKNHKLE_00464 5.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BPKNHKLE_00465 1.8e-167 corA P CorA-like Mg2+ transporter protein
BPKNHKLE_00466 2.6e-231 pbuX F xanthine permease
BPKNHKLE_00467 1e-151 qorB 1.6.5.2 GM NmrA-like family
BPKNHKLE_00468 2.5e-126 pgm3 G phosphoglycerate mutase family
BPKNHKLE_00469 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
BPKNHKLE_00470 2e-85
BPKNHKLE_00471 7.4e-107 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
BPKNHKLE_00472 8.8e-101 dps P Belongs to the Dps family
BPKNHKLE_00473 1.1e-31 copZ P Heavy-metal-associated domain
BPKNHKLE_00474 9.7e-292 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
BPKNHKLE_00475 1.3e-19 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
BPKNHKLE_00476 4.4e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
BPKNHKLE_00477 2.2e-179 iunH2 3.2.2.1 F nucleoside hydrolase
BPKNHKLE_00478 2.7e-100 S ABC-type cobalt transport system, permease component
BPKNHKLE_00479 2.1e-255 cbiO1 S ABC transporter, ATP-binding protein
BPKNHKLE_00480 5.7e-115 P Cobalt transport protein
BPKNHKLE_00481 1.2e-16 yvlA
BPKNHKLE_00482 0.0 yjcE P Sodium proton antiporter
BPKNHKLE_00483 4e-192 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
BPKNHKLE_00484 7.8e-73 O OsmC-like protein
BPKNHKLE_00485 4.1e-186 D Alpha beta
BPKNHKLE_00486 8.4e-75 K Transcriptional regulator
BPKNHKLE_00487 4.5e-160
BPKNHKLE_00488 6.6e-20
BPKNHKLE_00489 2.1e-59
BPKNHKLE_00490 3.1e-75 uspA T universal stress protein
BPKNHKLE_00492 9.7e-130 qmcA O prohibitin homologues
BPKNHKLE_00493 5.5e-245 glpT G Major Facilitator Superfamily
BPKNHKLE_00494 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BPKNHKLE_00495 2.3e-136 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
BPKNHKLE_00496 1.7e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BPKNHKLE_00497 1.8e-126 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BPKNHKLE_00498 6.2e-59 L Helix-turn-helix domain
BPKNHKLE_00499 7.3e-100 cfa 2.1.1.317, 2.1.1.79 M synthase
BPKNHKLE_00500 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding
BPKNHKLE_00501 6.3e-145 L 4.5 Transposon and IS
BPKNHKLE_00502 3.3e-29 L Transposase
BPKNHKLE_00503 1.2e-123 S Membrane
BPKNHKLE_00504 5.4e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
BPKNHKLE_00505 0.0 pepF E oligoendopeptidase F
BPKNHKLE_00506 1.7e-179 K helix_turn _helix lactose operon repressor
BPKNHKLE_00507 1.3e-137 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BPKNHKLE_00508 1.9e-77 K AsnC family
BPKNHKLE_00509 1.4e-81 uspA T universal stress protein
BPKNHKLE_00510 9.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BPKNHKLE_00511 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BPKNHKLE_00512 5.1e-207 yeaN P Transporter, major facilitator family protein
BPKNHKLE_00513 1.5e-74 S 3-demethylubiquinone-9 3-methyltransferase
BPKNHKLE_00514 9.2e-83 nrdI F Belongs to the NrdI family
BPKNHKLE_00515 3.6e-252 yhdP S Transporter associated domain
BPKNHKLE_00516 3e-90 GM epimerase
BPKNHKLE_00517 3.4e-86 M1-874 K Domain of unknown function (DUF1836)
BPKNHKLE_00518 2.6e-157 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
BPKNHKLE_00519 7.8e-266 pipD E Dipeptidase
BPKNHKLE_00520 9.4e-130
BPKNHKLE_00521 2.7e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BPKNHKLE_00522 6.4e-131 gntR K UbiC transcription regulator-associated domain protein
BPKNHKLE_00523 4.3e-149 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
BPKNHKLE_00524 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
BPKNHKLE_00526 1.4e-281 yjeM E Amino Acid
BPKNHKLE_00527 1.7e-187 K helix_turn _helix lactose operon repressor
BPKNHKLE_00528 9.8e-261 G PTS system Galactitol-specific IIC component
BPKNHKLE_00529 3.2e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BPKNHKLE_00530 4.3e-164 L Initiator Replication protein
BPKNHKLE_00534 6.7e-63 recD 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BPKNHKLE_00535 1.1e-56 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
BPKNHKLE_00536 1.6e-61
BPKNHKLE_00537 2.5e-189 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
BPKNHKLE_00538 1.2e-60 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BPKNHKLE_00539 0.0 dnaK O Heat shock 70 kDa protein
BPKNHKLE_00540 1.1e-177 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
BPKNHKLE_00541 2.8e-54 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BPKNHKLE_00542 1.6e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
BPKNHKLE_00543 1.9e-50 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
BPKNHKLE_00544 8.3e-167 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
BPKNHKLE_00545 6.4e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BPKNHKLE_00546 2.2e-108 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
BPKNHKLE_00547 2.6e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BPKNHKLE_00548 2.2e-102 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
BPKNHKLE_00549 1.2e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BPKNHKLE_00550 5.9e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BPKNHKLE_00551 5.6e-141 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
BPKNHKLE_00552 4.2e-55 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BPKNHKLE_00553 9.9e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
BPKNHKLE_00554 5.1e-201 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BPKNHKLE_00555 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
BPKNHKLE_00556 3.3e-09
BPKNHKLE_00557 1.9e-112 3.1.3.73 G phosphoglycerate mutase
BPKNHKLE_00558 3.2e-112 C aldo keto reductase
BPKNHKLE_00559 8.3e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BPKNHKLE_00560 4.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPKNHKLE_00561 2.7e-268 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
BPKNHKLE_00562 7.9e-79 K 2 iron, 2 sulfur cluster binding
BPKNHKLE_00563 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
BPKNHKLE_00564 9.2e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
BPKNHKLE_00565 9.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
BPKNHKLE_00566 3.4e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BPKNHKLE_00567 7.2e-54 C FMN binding
BPKNHKLE_00568 1.7e-28 T His Kinase A (phosphoacceptor) domain
BPKNHKLE_00569 7.8e-52 T Transcriptional regulatory protein, C terminal
BPKNHKLE_00570 1.2e-15 S ABC-type transport system involved in multi-copper enzyme maturation permease component
BPKNHKLE_00571 3.7e-221 iscS 2.8.1.7 E Aminotransferase class V
BPKNHKLE_00572 4.7e-123 srtA 3.4.22.70 M sortase family
BPKNHKLE_00573 3.3e-29 mdtG EGP Major facilitator Superfamily
BPKNHKLE_00574 6e-41 rpmE2 J Ribosomal protein L31
BPKNHKLE_00575 2.3e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BPKNHKLE_00576 1.1e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
BPKNHKLE_00577 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
BPKNHKLE_00578 5.5e-74 ywiB S Domain of unknown function (DUF1934)
BPKNHKLE_00579 4.3e-266 ywfO S HD domain protein
BPKNHKLE_00580 4.8e-143 yxeH S hydrolase
BPKNHKLE_00581 3e-32
BPKNHKLE_00582 3.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BPKNHKLE_00583 7.3e-205 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BPKNHKLE_00584 7.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
BPKNHKLE_00585 3.2e-128 znuB U ABC 3 transport family
BPKNHKLE_00586 5.4e-95 fhuC P ABC transporter
BPKNHKLE_00587 2.2e-165 znuA P Belongs to the bacterial solute-binding protein 9 family
BPKNHKLE_00588 1.3e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BPKNHKLE_00589 2.7e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
BPKNHKLE_00590 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BPKNHKLE_00591 1.8e-147 tatD L hydrolase, TatD family
BPKNHKLE_00592 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BPKNHKLE_00593 9.5e-163 yunF F Protein of unknown function DUF72
BPKNHKLE_00594 5.3e-212 norA EGP Major facilitator Superfamily
BPKNHKLE_00595 4.4e-129 cobB K SIR2 family
BPKNHKLE_00596 3.2e-186
BPKNHKLE_00597 6.2e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
BPKNHKLE_00598 2.5e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
BPKNHKLE_00599 0.0 helD 3.6.4.12 L DNA helicase
BPKNHKLE_00600 1.2e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
BPKNHKLE_00601 7.4e-155 metQ_4 P Belongs to the nlpA lipoprotein family
BPKNHKLE_00602 1.4e-168 D nuclear chromosome segregation
BPKNHKLE_00603 3.7e-258 dtpT U amino acid peptide transporter
BPKNHKLE_00604 2.1e-165 yjjH S Calcineurin-like phosphoesterase
BPKNHKLE_00607 1.1e-115
BPKNHKLE_00608 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
BPKNHKLE_00609 1.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
BPKNHKLE_00610 2.9e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BPKNHKLE_00611 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
BPKNHKLE_00612 0.0 yhgF K Tex-like protein N-terminal domain protein
BPKNHKLE_00613 2.4e-83 ydcK S Belongs to the SprT family
BPKNHKLE_00615 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
BPKNHKLE_00616 8.8e-189 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
BPKNHKLE_00617 2.3e-168 mleP2 S Sodium Bile acid symporter family
BPKNHKLE_00618 1.4e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BPKNHKLE_00619 1.3e-167 I alpha/beta hydrolase fold
BPKNHKLE_00620 6.8e-264 pepC 3.4.22.40 E Peptidase C1-like family
BPKNHKLE_00621 1.1e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
BPKNHKLE_00622 1.3e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BPKNHKLE_00623 4.2e-55 HA62_12640 S GCN5-related N-acetyl-transferase
BPKNHKLE_00624 1.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
BPKNHKLE_00625 5.6e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BPKNHKLE_00626 2.7e-205 yacL S domain protein
BPKNHKLE_00627 9.6e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BPKNHKLE_00628 7.8e-100 ywlG S Belongs to the UPF0340 family
BPKNHKLE_00629 6.5e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
BPKNHKLE_00630 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BPKNHKLE_00631 5.2e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BPKNHKLE_00632 1.1e-104 sigH K Belongs to the sigma-70 factor family
BPKNHKLE_00633 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BPKNHKLE_00634 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
BPKNHKLE_00635 5.9e-97 nusG K Participates in transcription elongation, termination and antitermination
BPKNHKLE_00636 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BPKNHKLE_00637 5.7e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
BPKNHKLE_00638 1.7e-243 steT E amino acid
BPKNHKLE_00639 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BPKNHKLE_00640 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
BPKNHKLE_00641 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
BPKNHKLE_00642 4.1e-176 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
BPKNHKLE_00643 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
BPKNHKLE_00644 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BPKNHKLE_00645 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
BPKNHKLE_00646 4.6e-247 brnQ U Component of the transport system for branched-chain amino acids
BPKNHKLE_00647 8.6e-195 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BPKNHKLE_00648 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BPKNHKLE_00649 2e-35 nrdH O Glutaredoxin
BPKNHKLE_00650 1.8e-79 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
BPKNHKLE_00652 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BPKNHKLE_00653 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BPKNHKLE_00654 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BPKNHKLE_00655 1.2e-20 S Protein of unknown function (DUF2508)
BPKNHKLE_00656 6e-117 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BPKNHKLE_00657 1.2e-52 yaaQ S Cyclic-di-AMP receptor
BPKNHKLE_00658 4.9e-193 holB 2.7.7.7 L DNA polymerase III
BPKNHKLE_00659 1.5e-55 yabA L Involved in initiation control of chromosome replication
BPKNHKLE_00660 1.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BPKNHKLE_00661 2.8e-145 fat 3.1.2.21 I Acyl-ACP thioesterase
BPKNHKLE_00662 1.1e-281 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
BPKNHKLE_00663 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BPKNHKLE_00664 2.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
BPKNHKLE_00665 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BPKNHKLE_00666 6.7e-148 KT YcbB domain
BPKNHKLE_00667 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BPKNHKLE_00668 3.2e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
BPKNHKLE_00669 8.2e-240 arcA 3.5.3.6 E Arginine
BPKNHKLE_00670 8.6e-257 E Arginine ornithine antiporter
BPKNHKLE_00671 2.7e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
BPKNHKLE_00672 7.6e-216 arcT 2.6.1.1 E Aminotransferase
BPKNHKLE_00673 2.2e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
BPKNHKLE_00674 7.4e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
BPKNHKLE_00675 1.2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BPKNHKLE_00677 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
BPKNHKLE_00678 8.7e-75 marR K Transcriptional regulator, MarR family
BPKNHKLE_00679 1.7e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BPKNHKLE_00680 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BPKNHKLE_00681 2.8e-171 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
BPKNHKLE_00682 2.7e-129 IQ reductase
BPKNHKLE_00683 1.3e-229 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
BPKNHKLE_00684 4.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
BPKNHKLE_00685 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
BPKNHKLE_00686 4.6e-263 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
BPKNHKLE_00687 4.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BPKNHKLE_00688 3.3e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
BPKNHKLE_00689 5.8e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
BPKNHKLE_00690 9.7e-92 bioY S BioY family
BPKNHKLE_00691 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
BPKNHKLE_00692 0.0 uup S ABC transporter, ATP-binding protein
BPKNHKLE_00693 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BPKNHKLE_00694 7.4e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BPKNHKLE_00695 1e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
BPKNHKLE_00696 0.0 ydaO E amino acid
BPKNHKLE_00697 1.9e-37
BPKNHKLE_00698 9e-113 yvyE 3.4.13.9 S YigZ family
BPKNHKLE_00699 2.9e-251 comFA L Helicase C-terminal domain protein
BPKNHKLE_00700 2.1e-128 comFC S Competence protein
BPKNHKLE_00701 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BPKNHKLE_00702 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BPKNHKLE_00703 4.5e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BPKNHKLE_00704 4.1e-53 KT PspC domain protein
BPKNHKLE_00705 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
BPKNHKLE_00706 1e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BPKNHKLE_00707 1.6e-162 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BPKNHKLE_00708 2.6e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
BPKNHKLE_00709 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
BPKNHKLE_00710 2.3e-147 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
BPKNHKLE_00711 2.9e-226 mtnE 2.6.1.83 E Aminotransferase
BPKNHKLE_00712 7.6e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BPKNHKLE_00713 1.5e-76 yphH S Cupin domain
BPKNHKLE_00714 1.7e-131 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
BPKNHKLE_00715 6e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
BPKNHKLE_00716 1.2e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
BPKNHKLE_00717 6.7e-243 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BPKNHKLE_00718 5.2e-241 yfnA E amino acid
BPKNHKLE_00719 1.6e-82 S NADPH-dependent FMN reductase
BPKNHKLE_00721 7.7e-157 L Thioesterase-like superfamily
BPKNHKLE_00722 1.1e-50 lacA S transferase hexapeptide repeat
BPKNHKLE_00723 4.7e-260 argH 4.3.2.1 E argininosuccinate lyase
BPKNHKLE_00724 1.3e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
BPKNHKLE_00725 4.1e-242 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BPKNHKLE_00726 2.7e-64 L Transposase IS200 like
BPKNHKLE_00727 8.2e-173 L transposase, IS605 OrfB family
BPKNHKLE_00728 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BPKNHKLE_00729 4.9e-102 K Transcriptional regulator
BPKNHKLE_00730 1.4e-22 XK27_06785 V ABC transporter
BPKNHKLE_00731 6.5e-168 M Membrane
BPKNHKLE_00732 2.8e-40 S FMN_bind
BPKNHKLE_00733 0.0 yhcA V ABC transporter, ATP-binding protein
BPKNHKLE_00734 6.1e-123 bm3R1 K Bacterial regulatory proteins, tetR family
BPKNHKLE_00735 2.5e-73 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BPKNHKLE_00736 2.9e-48 ybjQ S Belongs to the UPF0145 family
BPKNHKLE_00737 8e-78 rocF 3.5.3.1, 3.5.3.11 E Arginase family
BPKNHKLE_00739 1.8e-173 1.3.1.9 S Nitronate monooxygenase
BPKNHKLE_00740 4.7e-54 K Helix-turn-helix domain
BPKNHKLE_00741 1.2e-105 S Domain of unknown function (DUF4767)
BPKNHKLE_00742 7.7e-73
BPKNHKLE_00743 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
BPKNHKLE_00744 0.0 norZ 1.7.2.5 P Cytochrome C and Quinol oxidase polypeptide I
BPKNHKLE_00745 1.6e-170 pcaB 4.3.2.2 F Adenylosuccinate lyase C-terminus
BPKNHKLE_00746 1.1e-90 yxeQ S MmgE/PrpD family
BPKNHKLE_00748 4.2e-113 papP P ABC transporter, permease protein
BPKNHKLE_00749 4.5e-115 P ABC transporter permease
BPKNHKLE_00750 3.9e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
BPKNHKLE_00751 3.1e-153 cjaA ET ABC transporter substrate-binding protein
BPKNHKLE_00752 6.1e-137 IQ KR domain
BPKNHKLE_00754 7.3e-214 hom1 1.1.1.3 E Homoserine dehydrogenase
BPKNHKLE_00755 3.8e-156 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
BPKNHKLE_00756 2e-245 mmuP E amino acid
BPKNHKLE_00757 4.6e-174 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
BPKNHKLE_00758 1.4e-169 yniA G Phosphotransferase enzyme family
BPKNHKLE_00759 2.8e-174 lytH 3.5.1.28 M Ami_3
BPKNHKLE_00760 6.1e-196 6.3.1.20 H Lipoate-protein ligase
BPKNHKLE_00761 1e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
BPKNHKLE_00762 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
BPKNHKLE_00763 5.1e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
BPKNHKLE_00764 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
BPKNHKLE_00765 4.6e-71 yqeY S YqeY-like protein
BPKNHKLE_00766 1.1e-178 phoH T phosphate starvation-inducible protein PhoH
BPKNHKLE_00767 1.7e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BPKNHKLE_00768 1e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
BPKNHKLE_00769 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BPKNHKLE_00770 1.1e-155 recO L Involved in DNA repair and RecF pathway recombination
BPKNHKLE_00771 4.9e-187 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
BPKNHKLE_00772 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
BPKNHKLE_00773 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
BPKNHKLE_00774 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
BPKNHKLE_00780 7.9e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
BPKNHKLE_00781 3.9e-268 lysP E amino acid
BPKNHKLE_00783 1.3e-156 I alpha/beta hydrolase fold
BPKNHKLE_00784 2e-115 lssY 3.6.1.27 I phosphatase
BPKNHKLE_00785 2.8e-82 S Threonine/Serine exporter, ThrE
BPKNHKLE_00786 6.3e-126 thrE S Putative threonine/serine exporter
BPKNHKLE_00787 3.3e-29 cspA K Cold shock protein
BPKNHKLE_00788 4.4e-123 sirR K iron dependent repressor
BPKNHKLE_00789 1.6e-163 czcD P cation diffusion facilitator family transporter
BPKNHKLE_00790 1e-114 S membrane
BPKNHKLE_00791 1.1e-108 S VIT family
BPKNHKLE_00792 2.9e-81 usp1 T Belongs to the universal stress protein A family
BPKNHKLE_00793 8.1e-33 elaA S GNAT family
BPKNHKLE_00794 1.4e-215 S CAAX protease self-immunity
BPKNHKLE_00795 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BPKNHKLE_00796 4.4e-58
BPKNHKLE_00797 1.9e-74 merR K MerR HTH family regulatory protein
BPKNHKLE_00798 5.6e-267 lmrB EGP Major facilitator Superfamily
BPKNHKLE_00799 2.4e-114 S Domain of unknown function (DUF4811)
BPKNHKLE_00800 8.5e-150 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
BPKNHKLE_00801 7.2e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
BPKNHKLE_00803 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BPKNHKLE_00804 7.9e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
BPKNHKLE_00805 3.1e-189 I Alpha beta
BPKNHKLE_00806 1e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
BPKNHKLE_00807 9.5e-250 yjjP S Putative threonine/serine exporter
BPKNHKLE_00808 1.3e-162 mleR K LysR family transcriptional regulator
BPKNHKLE_00809 4e-127 narI 1.7.5.1 C Nitrate reductase
BPKNHKLE_00810 3.1e-102 narJ C Nitrate reductase delta subunit
BPKNHKLE_00811 0.0 narH 1.7.5.1 C Respiratory nitrate reductase beta C-terminal
BPKNHKLE_00812 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BPKNHKLE_00813 2.2e-187 moeB 2.7.7.73, 2.7.7.80 H ThiF family
BPKNHKLE_00814 4.3e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
BPKNHKLE_00815 4.1e-231 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
BPKNHKLE_00816 3.6e-84 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
BPKNHKLE_00817 5.3e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
BPKNHKLE_00818 4.2e-40
BPKNHKLE_00819 1.4e-77 nreA T GAF domain
BPKNHKLE_00820 3.9e-182 comP 2.7.13.3 F Sensor histidine kinase
BPKNHKLE_00821 4e-116 nreC K PFAM regulatory protein LuxR
BPKNHKLE_00822 1.2e-39
BPKNHKLE_00823 3e-184
BPKNHKLE_00824 2e-169 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
BPKNHKLE_00826 3e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
BPKNHKLE_00827 1e-162 hipB K Helix-turn-helix
BPKNHKLE_00828 1.5e-58 yitW S Iron-sulfur cluster assembly protein
BPKNHKLE_00829 1.1e-215 narK P Major Facilitator Superfamily
BPKNHKLE_00830 1e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BPKNHKLE_00831 6.4e-35 moaD 2.8.1.12 H ThiS family
BPKNHKLE_00832 2.2e-72 moaE 2.8.1.12 H MoaE protein
BPKNHKLE_00833 3.2e-56 S Flavodoxin
BPKNHKLE_00834 1.5e-170 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BPKNHKLE_00835 3.8e-142 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
BPKNHKLE_00836 2e-230 ndh 1.6.99.3 C NADH dehydrogenase
BPKNHKLE_00837 8e-54 yitW S Iron-sulfur cluster assembly protein
BPKNHKLE_00838 4.7e-19 M1-755 S Domain of unknown function (DUF1858)
BPKNHKLE_00839 4.3e-258 XK27_04775 S PAS domain
BPKNHKLE_00840 2.4e-142 EG EamA-like transporter family
BPKNHKLE_00844 2.5e-08
BPKNHKLE_00845 1.1e-100 S D5 N terminal like
BPKNHKLE_00846 7.9e-146 L DNA replication protein
BPKNHKLE_00849 4e-16 K Cro/C1-type HTH DNA-binding domain
BPKNHKLE_00850 2e-197 L Belongs to the 'phage' integrase family
BPKNHKLE_00851 2.2e-52 S Putative inner membrane protein (DUF1819)
BPKNHKLE_00852 1.4e-101 S Domain of unknown function (DUF1788)
BPKNHKLE_00853 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
BPKNHKLE_00854 0.0 2.1.1.72 V Eco57I restriction-modification methylase
BPKNHKLE_00855 3.6e-191 L Belongs to the 'phage' integrase family
BPKNHKLE_00856 2.7e-302 V Eco57I restriction-modification methylase
BPKNHKLE_00857 0.0 S PglZ domain
BPKNHKLE_00858 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
BPKNHKLE_00859 0.0 yfjM S Protein of unknown function DUF262
BPKNHKLE_00860 3.3e-15
BPKNHKLE_00861 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
BPKNHKLE_00862 1.2e-45 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
BPKNHKLE_00863 2.7e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BPKNHKLE_00864 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BPKNHKLE_00865 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BPKNHKLE_00866 1e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BPKNHKLE_00867 2.2e-131 stp 3.1.3.16 T phosphatase
BPKNHKLE_00868 0.0 KLT serine threonine protein kinase
BPKNHKLE_00869 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
BPKNHKLE_00870 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
BPKNHKLE_00871 4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
BPKNHKLE_00872 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
BPKNHKLE_00873 3.6e-58 asp S Asp23 family, cell envelope-related function
BPKNHKLE_00874 5e-304 yloV S DAK2 domain fusion protein YloV
BPKNHKLE_00875 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BPKNHKLE_00876 2.8e-164 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
BPKNHKLE_00877 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BPKNHKLE_00878 4e-130 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
BPKNHKLE_00879 0.0 smc D Required for chromosome condensation and partitioning
BPKNHKLE_00880 1.1e-183 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BPKNHKLE_00881 1.1e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BPKNHKLE_00882 2.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BPKNHKLE_00885 5.3e-62
BPKNHKLE_00886 8.6e-276 lacS G Transporter
BPKNHKLE_00887 0.0 rafA 3.2.1.22 G alpha-galactosidase
BPKNHKLE_00888 2.3e-179 galR K Transcriptional regulator
BPKNHKLE_00889 3.1e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
BPKNHKLE_00890 2.1e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BPKNHKLE_00891 1.4e-183 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
BPKNHKLE_00892 4.6e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
BPKNHKLE_00893 2.7e-96 yxkA S Phosphatidylethanolamine-binding protein
BPKNHKLE_00894 2e-35
BPKNHKLE_00895 6.6e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
BPKNHKLE_00896 2.2e-117 tcyB U Binding-protein-dependent transport system inner membrane component
BPKNHKLE_00897 3.7e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
BPKNHKLE_00898 2e-52
BPKNHKLE_00899 4e-170 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPKNHKLE_00900 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BPKNHKLE_00901 4.5e-146 pnuC H nicotinamide mononucleotide transporter
BPKNHKLE_00902 1.1e-92 ymdB S Macro domain protein
BPKNHKLE_00903 0.0 pepO 3.4.24.71 O Peptidase family M13
BPKNHKLE_00904 1.8e-229 pbuG S permease
BPKNHKLE_00905 2.1e-45
BPKNHKLE_00906 4.9e-213 S Putative metallopeptidase domain
BPKNHKLE_00907 8e-205 3.1.3.1 S associated with various cellular activities
BPKNHKLE_00908 1.3e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
BPKNHKLE_00909 6.8e-65 yeaO S Protein of unknown function, DUF488
BPKNHKLE_00911 1.4e-124 yrkL S Flavodoxin-like fold
BPKNHKLE_00912 1.5e-55
BPKNHKLE_00913 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
BPKNHKLE_00914 1.1e-37 K transcriptional regulator
BPKNHKLE_00915 2.1e-166 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
BPKNHKLE_00916 6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BPKNHKLE_00917 8.3e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
BPKNHKLE_00918 4.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BPKNHKLE_00919 1.4e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
BPKNHKLE_00920 1.1e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BPKNHKLE_00921 1.8e-21 gntT EG gluconate transmembrane transporter activity
BPKNHKLE_00922 6.9e-47
BPKNHKLE_00923 1.9e-273 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
BPKNHKLE_00924 5.1e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
BPKNHKLE_00925 2.7e-149 metQ1 P Belongs to the nlpA lipoprotein family
BPKNHKLE_00926 6.1e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BPKNHKLE_00927 5.8e-97 metI P ABC transporter permease
BPKNHKLE_00928 6.4e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
BPKNHKLE_00929 8.9e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BPKNHKLE_00930 1.6e-196 brnQ U Component of the transport system for branched-chain amino acids
BPKNHKLE_00931 2.4e-122 iolS C Aldo keto reductase
BPKNHKLE_00932 7.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BPKNHKLE_00933 1.6e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BPKNHKLE_00934 1.6e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
BPKNHKLE_00935 2.4e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BPKNHKLE_00937 1.5e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
BPKNHKLE_00938 3.6e-134 pnuC H nicotinamide mononucleotide transporter
BPKNHKLE_00939 2.5e-297 ybeC E amino acid
BPKNHKLE_00940 8.7e-107 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPKNHKLE_00941 1.6e-141 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
BPKNHKLE_00942 1.3e-101 G Glycosyl hydrolases family 8
BPKNHKLE_00943 9.3e-09 G Glycosyl hydrolases family 8
BPKNHKLE_00944 3.3e-186 ydaM M Glycosyl transferase family group 2
BPKNHKLE_00946 2.6e-78
BPKNHKLE_00947 5.3e-207 V domain protein
BPKNHKLE_00948 1.9e-92 K Transcriptional regulator (TetR family)
BPKNHKLE_00949 8.1e-188 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
BPKNHKLE_00950 6.3e-168
BPKNHKLE_00952 4e-83 zur P Belongs to the Fur family
BPKNHKLE_00953 1.7e-105 gmk2 2.7.4.8 F Guanylate kinase
BPKNHKLE_00954 1.3e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
BPKNHKLE_00955 1.1e-205 yfnA E Amino Acid
BPKNHKLE_00956 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
BPKNHKLE_00957 1.2e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
BPKNHKLE_00958 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BPKNHKLE_00959 7.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BPKNHKLE_00960 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BPKNHKLE_00961 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
BPKNHKLE_00962 2.8e-257 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
BPKNHKLE_00963 3e-87 yabR J RNA binding
BPKNHKLE_00964 1.5e-56 divIC D Septum formation initiator
BPKNHKLE_00965 1.6e-39 yabO J S4 domain protein
BPKNHKLE_00966 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BPKNHKLE_00967 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
BPKNHKLE_00968 8.1e-114 S (CBS) domain
BPKNHKLE_00969 5e-57 L Toxic component of a toxin-antitoxin (TA) module
BPKNHKLE_00970 9.6e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BPKNHKLE_00971 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
BPKNHKLE_00972 1.9e-254 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
BPKNHKLE_00973 1.4e-259 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
BPKNHKLE_00974 4.9e-157 htpX O Belongs to the peptidase M48B family
BPKNHKLE_00975 8.7e-88 lemA S LemA family
BPKNHKLE_00976 9e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BPKNHKLE_00977 1.1e-96 L Probable transposase
BPKNHKLE_00978 3.3e-16 EGP Major Facilitator Superfamily
BPKNHKLE_00979 7.4e-76 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
BPKNHKLE_00980 1e-72 O OsmC-like protein
BPKNHKLE_00981 4.7e-76 K Transcriptional regulator
BPKNHKLE_00982 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
BPKNHKLE_00983 6.7e-108 proWZ P ABC transporter permease
BPKNHKLE_00984 9.3e-141 proV E ABC transporter, ATP-binding protein
BPKNHKLE_00985 6.6e-100 proW P ABC transporter, permease protein
BPKNHKLE_00986 8.8e-181 C Zinc-binding dehydrogenase
BPKNHKLE_00987 6.3e-196 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
BPKNHKLE_00988 1.2e-224 4.4.1.8 E Aminotransferase, class I
BPKNHKLE_00989 1.2e-179 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
BPKNHKLE_00990 7.1e-203 xerS L Belongs to the 'phage' integrase family
BPKNHKLE_00991 1.2e-61 ywkB S Membrane transport protein
BPKNHKLE_00992 9.6e-236 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
BPKNHKLE_00993 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
BPKNHKLE_00994 3.4e-80 hmpT S ECF-type riboflavin transporter, S component
BPKNHKLE_00995 5.6e-166 1.1.1.346 C Aldo keto reductase
BPKNHKLE_00996 8.9e-162 S DUF218 domain
BPKNHKLE_00998 6.3e-96 K Acetyltransferase (GNAT) domain
BPKNHKLE_00999 1.3e-164 I alpha/beta hydrolase fold
BPKNHKLE_01000 4.7e-120 S Phage minor capsid protein 2
BPKNHKLE_01003 3.4e-216 2.6.1.1 E Aminotransferase
BPKNHKLE_01004 1.5e-104 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
BPKNHKLE_01005 8e-70 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
BPKNHKLE_01006 4.1e-63 EGP Sugar (and other) transporter
BPKNHKLE_01007 3.6e-53 EGP Sugar (and other) transporter
BPKNHKLE_01008 1.9e-93 EGP Sugar (and other) transporter
BPKNHKLE_01009 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
BPKNHKLE_01010 1.3e-85 S Fic/DOC family
BPKNHKLE_01011 8.1e-77 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
BPKNHKLE_01012 3.1e-105 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
BPKNHKLE_01013 4.5e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
BPKNHKLE_01014 1.7e-260 arcD E Amino acid permease
BPKNHKLE_01015 2.2e-118 5.1.1.13 M racemase activity, acting on amino acids and derivatives
BPKNHKLE_01016 9.5e-36 odh 1.5.1.28 C NAD NADP octopine nopaline dehydrogenase
BPKNHKLE_01017 3.5e-110 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
BPKNHKLE_01018 1.7e-29 clcA P chloride
BPKNHKLE_01019 2.3e-67 clcA P chloride
BPKNHKLE_01020 6.5e-18 lmrB EGP Major facilitator Superfamily
BPKNHKLE_01021 9.3e-245 yhjX P Major Facilitator Superfamily
BPKNHKLE_01022 4.4e-118 S Protein of unknown function (DUF554)
BPKNHKLE_01023 2.6e-255 rarA L recombination factor protein RarA
BPKNHKLE_01025 0.0 oppD EP Psort location Cytoplasmic, score
BPKNHKLE_01026 8e-243 codA 3.5.4.1 F cytosine deaminase
BPKNHKLE_01027 4.7e-244 U Belongs to the purine-cytosine permease (2.A.39) family
BPKNHKLE_01028 2.2e-81 yebR 1.8.4.14 T GAF domain-containing protein
BPKNHKLE_01029 5.7e-94 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
BPKNHKLE_01030 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
BPKNHKLE_01031 2.3e-71 yqkB S Belongs to the HesB IscA family
BPKNHKLE_01032 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
BPKNHKLE_01033 5.2e-95 S Protein of unknown function (DUF1440)
BPKNHKLE_01034 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BPKNHKLE_01035 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BPKNHKLE_01036 2.8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
BPKNHKLE_01037 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
BPKNHKLE_01038 7.3e-155 D DNA integration
BPKNHKLE_01039 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BPKNHKLE_01040 8.1e-165 dprA LU DNA protecting protein DprA
BPKNHKLE_01041 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BPKNHKLE_01042 1.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BPKNHKLE_01043 3.1e-36 yozE S Belongs to the UPF0346 family
BPKNHKLE_01044 2.7e-103 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
BPKNHKLE_01045 1.1e-167 ypmR E lipolytic protein G-D-S-L family
BPKNHKLE_01046 3.2e-107 cat S Bacterial transferase hexapeptide (six repeats)
BPKNHKLE_01047 2.9e-218 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
BPKNHKLE_01048 1.2e-152 DegV S EDD domain protein, DegV family
BPKNHKLE_01049 1.2e-109 hlyIII S protein, hemolysin III
BPKNHKLE_01050 2.5e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BPKNHKLE_01051 2.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BPKNHKLE_01052 0.0 yfmR S ABC transporter, ATP-binding protein
BPKNHKLE_01053 7.6e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BPKNHKLE_01054 1.8e-164 xerD L Phage integrase, N-terminal SAM-like domain
BPKNHKLE_01055 1.8e-234 S Tetratricopeptide repeat protein
BPKNHKLE_01056 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
BPKNHKLE_01057 7.4e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
BPKNHKLE_01058 1.7e-208 rpsA 1.17.7.4 J Ribosomal protein S1
BPKNHKLE_01059 5.8e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
BPKNHKLE_01060 9.7e-31 M Lysin motif
BPKNHKLE_01061 3.1e-278 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
BPKNHKLE_01062 3.9e-198 ypbB 5.1.3.1 S Helix-turn-helix domain
BPKNHKLE_01063 3.7e-81 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BPKNHKLE_01064 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BPKNHKLE_01065 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BPKNHKLE_01066 3.9e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BPKNHKLE_01067 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BPKNHKLE_01068 5.3e-132 xerD D recombinase XerD
BPKNHKLE_01069 1.6e-168 cvfB S S1 domain
BPKNHKLE_01070 7e-267 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
BPKNHKLE_01071 0.0 dnaE 2.7.7.7 L DNA polymerase
BPKNHKLE_01073 5.6e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
BPKNHKLE_01074 6.5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BPKNHKLE_01075 4.5e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
BPKNHKLE_01076 2e-118 ktrA P domain protein
BPKNHKLE_01077 3e-227 ktrB P Potassium uptake protein
BPKNHKLE_01078 3.3e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BPKNHKLE_01079 1.7e-218 patA 2.6.1.1 E Aminotransferase
BPKNHKLE_01080 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
BPKNHKLE_01081 9.2e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BPKNHKLE_01082 1.8e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
BPKNHKLE_01083 2.9e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
BPKNHKLE_01084 2.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
BPKNHKLE_01085 6.5e-262 lysC 2.7.2.4 E Belongs to the aspartokinase family
BPKNHKLE_01086 6.7e-179 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BPKNHKLE_01087 1.1e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
BPKNHKLE_01088 1.4e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPKNHKLE_01089 3.9e-33 yneR S Belongs to the HesB IscA family
BPKNHKLE_01090 3.6e-140 S NADPH-dependent FMN reductase
BPKNHKLE_01091 3.1e-289 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
BPKNHKLE_01092 1.9e-161 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
BPKNHKLE_01093 1.4e-104 yvdD 3.2.2.10 S Belongs to the LOG family
BPKNHKLE_01094 4.9e-63 S Domain of unknown function (DUF4828)
BPKNHKLE_01095 1.1e-189 mocA S Oxidoreductase
BPKNHKLE_01096 8.9e-232 yfmL 3.6.4.13 L DEAD DEAH box helicase
BPKNHKLE_01098 3.6e-73 gtcA S Teichoic acid glycosylation protein
BPKNHKLE_01099 8.5e-78 fld C Flavodoxin
BPKNHKLE_01100 5e-167 map 3.4.11.18 E Methionine Aminopeptidase
BPKNHKLE_01101 0.0 XK27_08315 M Sulfatase
BPKNHKLE_01102 2.7e-139 yihY S Belongs to the UPF0761 family
BPKNHKLE_01103 3.8e-31 S Protein of unknown function (DUF2922)
BPKNHKLE_01104 1.3e-07
BPKNHKLE_01105 4.2e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
BPKNHKLE_01106 1.1e-118 rfbP M Bacterial sugar transferase
BPKNHKLE_01107 4.6e-148 cps1D M Domain of unknown function (DUF4422)
BPKNHKLE_01108 1.2e-94 cps3F
BPKNHKLE_01109 4.5e-45 M biosynthesis protein
BPKNHKLE_01110 1.4e-52 cps3I G Acyltransferase family
BPKNHKLE_01111 5.8e-171 scrK 2.7.1.2, 2.7.1.4 GK ROK family
BPKNHKLE_01112 8.6e-235 mepA V MATE efflux family protein
BPKNHKLE_01113 9.7e-225 amtB P ammonium transporter
BPKNHKLE_01115 4.2e-133 XK27_08845 S ABC transporter, ATP-binding protein
BPKNHKLE_01116 1e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
BPKNHKLE_01117 7e-181 ABC-SBP S ABC transporter
BPKNHKLE_01118 5.8e-291 S ABC transporter, ATP-binding protein
BPKNHKLE_01119 1.8e-206 nrnB S DHHA1 domain
BPKNHKLE_01121 5.1e-110 M ErfK YbiS YcfS YnhG
BPKNHKLE_01122 1.4e-83 nrdI F NrdI Flavodoxin like
BPKNHKLE_01123 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BPKNHKLE_01124 9.7e-169 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
BPKNHKLE_01125 1.2e-182 1.17.4.1 F Ribonucleotide reductase, small chain
BPKNHKLE_01126 5e-275 S Uncharacterized protein conserved in bacteria (DUF2325)
BPKNHKLE_01127 2.3e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
BPKNHKLE_01128 3.1e-178 3.4.11.5 E Releases the N-terminal proline from various substrates
BPKNHKLE_01129 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
BPKNHKLE_01130 6e-108 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BPKNHKLE_01131 1.1e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
BPKNHKLE_01132 5.7e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BPKNHKLE_01133 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BPKNHKLE_01134 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BPKNHKLE_01135 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BPKNHKLE_01136 2.5e-135 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
BPKNHKLE_01137 5.9e-243 S response to antibiotic
BPKNHKLE_01138 2.1e-172 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
BPKNHKLE_01139 3.3e-255 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BPKNHKLE_01140 7.7e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BPKNHKLE_01141 1.8e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BPKNHKLE_01142 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
BPKNHKLE_01143 3.7e-164 K AI-2E family transporter
BPKNHKLE_01144 3.1e-10 K transcriptional regulator
BPKNHKLE_01145 1.9e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
BPKNHKLE_01146 4.7e-14
BPKNHKLE_01147 4e-156 V ABC transporter, ATP-binding protein
BPKNHKLE_01148 7.8e-64 gntR1 K Transcriptional regulator, GntR family
BPKNHKLE_01149 1.4e-170 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
BPKNHKLE_01150 6.5e-89 S Bacterial membrane protein, YfhO
BPKNHKLE_01151 5.9e-212 S Psort location CytoplasmicMembrane, score
BPKNHKLE_01152 3.6e-148 ykoT GT2 M Glycosyl transferase family 2
BPKNHKLE_01153 3.1e-103 glfT1 1.1.1.133 S Glycosyltransferase like family 2
BPKNHKLE_01154 1.3e-95 M transferase activity, transferring glycosyl groups
BPKNHKLE_01155 2.2e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BPKNHKLE_01156 5.9e-164 ykoT GT2 M Glycosyl transferase family 2
BPKNHKLE_01157 1.4e-140 yueF S AI-2E family transporter
BPKNHKLE_01158 3.8e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
BPKNHKLE_01159 8.1e-09
BPKNHKLE_01160 1.2e-59 M repeat protein
BPKNHKLE_01161 1.9e-56 acmD 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
BPKNHKLE_01162 1.3e-100 P Cadmium resistance transporter
BPKNHKLE_01163 3.2e-116 S Protein of unknown function (DUF554)
BPKNHKLE_01164 7.1e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BPKNHKLE_01165 3.5e-157 P Belongs to the nlpA lipoprotein family
BPKNHKLE_01166 3.9e-98 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BPKNHKLE_01167 2.5e-37 V CAAX protease self-immunity
BPKNHKLE_01168 1.7e-67 psiE S Phosphate-starvation-inducible E
BPKNHKLE_01169 7.6e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
BPKNHKLE_01170 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
BPKNHKLE_01171 6.1e-143 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
BPKNHKLE_01172 6.2e-140 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BPKNHKLE_01173 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BPKNHKLE_01174 1.1e-90 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
BPKNHKLE_01175 2.6e-101 2.1.1.72, 3.1.21.4 L Eco57I restriction-modification methylase
BPKNHKLE_01176 0.0 L Type III restriction enzyme, res subunit
BPKNHKLE_01177 3.2e-254 S Protein of unknown function DUF262
BPKNHKLE_01179 1.1e-15 tnp L MULE transposase domain
BPKNHKLE_01180 3.8e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
BPKNHKLE_01181 6.2e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
BPKNHKLE_01182 1.4e-136 cof S haloacid dehalogenase-like hydrolase
BPKNHKLE_01183 1.1e-19 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
BPKNHKLE_01184 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
BPKNHKLE_01185 6.8e-113 yfbR S HD containing hydrolase-like enzyme
BPKNHKLE_01187 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
BPKNHKLE_01188 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
BPKNHKLE_01189 6.9e-206
BPKNHKLE_01190 3.2e-161 rapZ S Displays ATPase and GTPase activities
BPKNHKLE_01191 1.7e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
BPKNHKLE_01192 6e-166 whiA K May be required for sporulation
BPKNHKLE_01193 5e-119 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BPKNHKLE_01194 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
BPKNHKLE_01198 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
BPKNHKLE_01199 6.5e-182 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BPKNHKLE_01200 1.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
BPKNHKLE_01201 5e-229 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
BPKNHKLE_01202 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BPKNHKLE_01203 4.7e-39 ptsH G phosphocarrier protein HPR
BPKNHKLE_01205 0.0 clpE O Belongs to the ClpA ClpB family
BPKNHKLE_01206 6.4e-128 3.6.1.13, 3.6.1.55 F NUDIX domain
BPKNHKLE_01207 6.4e-110 pncA Q Isochorismatase family
BPKNHKLE_01208 1.3e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BPKNHKLE_01209 1.7e-97 S Pfam:DUF3816
BPKNHKLE_01210 3.6e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
BPKNHKLE_01211 8.4e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BPKNHKLE_01212 6.5e-162 EG EamA-like transporter family
BPKNHKLE_01213 1.2e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
BPKNHKLE_01215 5.5e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPKNHKLE_01218 4e-22
BPKNHKLE_01219 4.5e-247 cycA E Amino acid permease
BPKNHKLE_01220 4.8e-84 perR P Belongs to the Fur family
BPKNHKLE_01221 5.2e-254 EGP Major facilitator Superfamily
BPKNHKLE_01222 4.4e-97 tag 3.2.2.20 L glycosylase
BPKNHKLE_01223 8.5e-51
BPKNHKLE_01224 3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BPKNHKLE_01225 4.8e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BPKNHKLE_01226 9.9e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BPKNHKLE_01227 4.1e-127 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
BPKNHKLE_01228 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
BPKNHKLE_01229 2.6e-42
BPKNHKLE_01230 8e-299 ytgP S Polysaccharide biosynthesis protein
BPKNHKLE_01231 3.5e-97 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPKNHKLE_01232 6.1e-10 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BPKNHKLE_01233 1.2e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BPKNHKLE_01234 1.9e-186 yegS 2.7.1.107 G Lipid kinase
BPKNHKLE_01235 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BPKNHKLE_01236 2e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
BPKNHKLE_01237 1e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BPKNHKLE_01238 4.6e-165 camS S sex pheromone
BPKNHKLE_01239 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BPKNHKLE_01240 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
BPKNHKLE_01241 1.4e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BPKNHKLE_01242 3.2e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
BPKNHKLE_01243 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
BPKNHKLE_01244 1.2e-138 IQ reductase
BPKNHKLE_01245 2.9e-125 tnp L DDE domain
BPKNHKLE_01246 4.9e-103
BPKNHKLE_01248 8.8e-30 S Protein of unknown function (DUF3021)
BPKNHKLE_01249 3.1e-27 K LytTr DNA-binding domain
BPKNHKLE_01250 6.6e-32 K Transcriptional regulator, ArsR family
BPKNHKLE_01251 6.2e-57 P Cadmium resistance transporter
BPKNHKLE_01252 8e-42 S RelB antitoxin
BPKNHKLE_01253 2.7e-13
BPKNHKLE_01254 6.7e-156 repA S Replication initiator protein A
BPKNHKLE_01256 1.1e-141 D CobQ CobB MinD ParA nucleotide binding domain protein
BPKNHKLE_01257 1.4e-93 L Resolvase, N terminal domain
BPKNHKLE_01258 8.1e-236 EGP Major Facilitator Superfamily
BPKNHKLE_01259 2.1e-311 mco Q Multicopper oxidase
BPKNHKLE_01260 6.8e-24
BPKNHKLE_01261 6.1e-18 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
BPKNHKLE_01262 0.0 asnB 6.3.5.4 E Aluminium induced protein
BPKNHKLE_01264 3.8e-103 L Transposase and inactivated derivatives
BPKNHKLE_01265 1e-188 EGP Major facilitator Superfamily
BPKNHKLE_01268 5.1e-104 S Bacterial transferase hexapeptide (six repeats)
BPKNHKLE_01269 7.8e-120 IQ Enoyl-(Acyl carrier protein) reductase
BPKNHKLE_01270 2.8e-199 gldA 1.1.1.6 C dehydrogenase
BPKNHKLE_01271 4.5e-17 xre K Helix-turn-helix domain
BPKNHKLE_01272 2.1e-51 S Sugar efflux transporter for intercellular exchange
BPKNHKLE_01273 2e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
BPKNHKLE_01274 9e-22 S Protein conserved in bacteria
BPKNHKLE_01275 1.8e-98 ywrO S Flavodoxin-like fold
BPKNHKLE_01276 1.7e-41 K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BPKNHKLE_01277 2.5e-152 tesE Q hydratase
BPKNHKLE_01278 1.9e-186 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPKNHKLE_01279 3.6e-61 S Domain of unknown function (DUF4440)
BPKNHKLE_01280 2.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BPKNHKLE_01281 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
BPKNHKLE_01282 1.9e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
BPKNHKLE_01283 8.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
BPKNHKLE_01284 1.9e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BPKNHKLE_01285 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
BPKNHKLE_01286 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
BPKNHKLE_01288 8.3e-53 MA20_27270 S mazG nucleotide pyrophosphohydrolase
BPKNHKLE_01289 2.8e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
BPKNHKLE_01290 1.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BPKNHKLE_01291 5.7e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BPKNHKLE_01292 4.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BPKNHKLE_01293 1.2e-163 S Tetratricopeptide repeat
BPKNHKLE_01294 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BPKNHKLE_01295 1.9e-261 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
BPKNHKLE_01296 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BPKNHKLE_01297 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
BPKNHKLE_01298 1.8e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
BPKNHKLE_01299 0.0 comEC S Competence protein ComEC
BPKNHKLE_01300 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
BPKNHKLE_01301 3.8e-90 comEA L Competence protein ComEA
BPKNHKLE_01302 6.7e-198 ylbL T Belongs to the peptidase S16 family
BPKNHKLE_01303 9.6e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BPKNHKLE_01304 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
BPKNHKLE_01305 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
BPKNHKLE_01306 2e-214 ftsW D Belongs to the SEDS family
BPKNHKLE_01307 0.0 typA T GTP-binding protein TypA
BPKNHKLE_01308 1.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
BPKNHKLE_01309 2.4e-49 yktA S Belongs to the UPF0223 family
BPKNHKLE_01310 7.5e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
BPKNHKLE_01311 9.8e-74
BPKNHKLE_01312 6.5e-31 ykzG S Belongs to the UPF0356 family
BPKNHKLE_01313 9e-189 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
BPKNHKLE_01314 4.2e-74 spx4 1.20.4.1 P ArsC family
BPKNHKLE_01315 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BPKNHKLE_01316 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
BPKNHKLE_01317 7.1e-124 S Repeat protein
BPKNHKLE_01318 1.6e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
BPKNHKLE_01319 4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
BPKNHKLE_01320 1.3e-306 S amidohydrolase
BPKNHKLE_01321 2.9e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
BPKNHKLE_01322 3.4e-58 XK27_04120 S Putative amino acid metabolism
BPKNHKLE_01323 1.3e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BPKNHKLE_01325 7.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
BPKNHKLE_01326 1.2e-32 cspB K Cold shock protein
BPKNHKLE_01327 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BPKNHKLE_01329 4.8e-112 divIVA D DivIVA domain protein
BPKNHKLE_01330 2.9e-145 ylmH S S4 domain protein
BPKNHKLE_01331 6.8e-41 yggT S YGGT family
BPKNHKLE_01332 2.3e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
BPKNHKLE_01333 4.5e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BPKNHKLE_01334 3.2e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
BPKNHKLE_01335 8.4e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
BPKNHKLE_01336 2.8e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BPKNHKLE_01337 4.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BPKNHKLE_01338 3.5e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BPKNHKLE_01339 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
BPKNHKLE_01340 7e-09 ftsL D Cell division protein FtsL
BPKNHKLE_01341 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
BPKNHKLE_01342 1.2e-79 mraZ K Belongs to the MraZ family
BPKNHKLE_01343 9.8e-58
BPKNHKLE_01344 1.2e-07 S Protein of unknown function (DUF4044)
BPKNHKLE_01345 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
BPKNHKLE_01346 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
BPKNHKLE_01347 2.5e-163 rrmA 2.1.1.187 H Methyltransferase
BPKNHKLE_01348 1.4e-195 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
BPKNHKLE_01349 8.2e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
BPKNHKLE_01350 1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BPKNHKLE_01351 6e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
BPKNHKLE_01352 8.1e-108 yjbH Q Thioredoxin
BPKNHKLE_01353 9.4e-205 coiA 3.6.4.12 S Competence protein
BPKNHKLE_01354 4.5e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
BPKNHKLE_01355 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
BPKNHKLE_01356 4.6e-16 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
BPKNHKLE_01357 3.1e-13 lacA 3.2.1.23 G -beta-galactosidase
BPKNHKLE_01358 3.8e-213 nupG F Nucleoside transporter
BPKNHKLE_01359 2.2e-144 rihC 3.2.2.1 F Nucleoside
BPKNHKLE_01360 1.3e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
BPKNHKLE_01361 4.6e-158 noc K Belongs to the ParB family
BPKNHKLE_01362 1e-145 spo0J K Belongs to the ParB family
BPKNHKLE_01363 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
BPKNHKLE_01364 4.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
BPKNHKLE_01365 5.9e-135 XK27_01040 S Protein of unknown function (DUF1129)
BPKNHKLE_01366 1.7e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
BPKNHKLE_01367 3.1e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
BPKNHKLE_01368 8.2e-129 epsB M biosynthesis protein
BPKNHKLE_01369 6.1e-113 ywqD 2.7.10.1 D Capsular exopolysaccharide family
BPKNHKLE_01370 1.1e-138 ywqE 3.1.3.48 GM PHP domain protein
BPKNHKLE_01371 5.2e-89 capM M Bacterial sugar transferase
BPKNHKLE_01372 5e-85 GT4 G Glycosyl transferase 4-like
BPKNHKLE_01373 1.9e-145 3.5.1.47 E Peptidase dimerisation domain
BPKNHKLE_01374 1.2e-78 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
BPKNHKLE_01375 2.2e-70 yxeN U ABC transporter, permease protein
BPKNHKLE_01376 5.4e-47 yxeL K acetyltransferase
BPKNHKLE_01377 1.8e-67 yxeM ET Bacterial periplasmic substrate-binding proteins
BPKNHKLE_01379 4.8e-210 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
BPKNHKLE_01380 1.9e-44 metC1 2.5.1.48, 4.4.1.8 E cystathionine
BPKNHKLE_01381 6e-163 metC1 2.5.1.48, 4.4.1.8 E cystathionine
BPKNHKLE_01382 3.5e-85 slyA K Transcriptional regulator
BPKNHKLE_01383 2.7e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
BPKNHKLE_01384 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BPKNHKLE_01385 4.4e-58
BPKNHKLE_01386 6.8e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
BPKNHKLE_01387 2e-177 prmA J Ribosomal protein L11 methyltransferase
BPKNHKLE_01388 1.2e-54
BPKNHKLE_01390 5.2e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
BPKNHKLE_01401 1.3e-11 qacC P COG2076 Membrane transporters of cations and cationic drugs
BPKNHKLE_01402 9e-142 ET Bacterial periplasmic substrate-binding proteins
BPKNHKLE_01403 2e-110 XK27_05795 P ABC transporter permease
BPKNHKLE_01404 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
BPKNHKLE_01405 5.3e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BPKNHKLE_01406 5.4e-161 sufD O Uncharacterized protein family (UPF0051)
BPKNHKLE_01407 4.6e-236 F Permease
BPKNHKLE_01408 1e-198 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
BPKNHKLE_01409 4.7e-66 lytE M LysM domain protein
BPKNHKLE_01410 6.2e-85 ykhA 3.1.2.20 I Thioesterase superfamily
BPKNHKLE_01411 1.1e-77 hsp O Belongs to the small heat shock protein (HSP20) family
BPKNHKLE_01412 1.2e-115 K Transcriptional regulator, TetR family
BPKNHKLE_01413 4.3e-183
BPKNHKLE_01414 5.9e-76
BPKNHKLE_01415 2.1e-65 yjcE P Sodium proton antiporter
BPKNHKLE_01416 2.4e-49 ywnB S NAD(P)H-binding
BPKNHKLE_01417 3.1e-289 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
BPKNHKLE_01418 2.2e-96 V VanZ like family
BPKNHKLE_01419 2.8e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
BPKNHKLE_01420 6.1e-60 yneR
BPKNHKLE_01421 1.9e-181 K Transcriptional regulator, LacI family
BPKNHKLE_01422 1.6e-228 gntT EG Gluconate
BPKNHKLE_01423 1.6e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
BPKNHKLE_01424 1.6e-171 mutR K Transcriptional activator, Rgg GadR MutR family
BPKNHKLE_01425 9e-12 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
BPKNHKLE_01426 9.7e-74 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
BPKNHKLE_01427 8.7e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
BPKNHKLE_01428 0.0 sbcC L Putative exonuclease SbcCD, C subunit
BPKNHKLE_01429 5.7e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BPKNHKLE_01431 3.5e-188 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
BPKNHKLE_01433 1.2e-226 glnP P ABC transporter
BPKNHKLE_01434 4.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
BPKNHKLE_01435 1e-251 cycA E Amino acid permease
BPKNHKLE_01436 1.6e-208 EGP Major facilitator Superfamily
BPKNHKLE_01437 2.7e-211 ycsG P Natural resistance-associated macrophage protein
BPKNHKLE_01438 2e-124 ycsF S LamB/YcsF family
BPKNHKLE_01439 2.2e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
BPKNHKLE_01440 4.8e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
BPKNHKLE_01441 1.7e-190 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
BPKNHKLE_01442 1.6e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
BPKNHKLE_01443 2.3e-72 K helix_turn_helix, mercury resistance
BPKNHKLE_01444 5.9e-82 S Psort location Cytoplasmic, score
BPKNHKLE_01445 4.2e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
BPKNHKLE_01446 9.9e-94 wecD K Acetyltransferase (GNAT) family
BPKNHKLE_01447 6.4e-105 3.2.1.17 NU mannosyl-glycoprotein
BPKNHKLE_01448 1e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
BPKNHKLE_01449 1.1e-23 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
BPKNHKLE_01450 1.1e-26 L Transposase and inactivated derivatives IS30 family
BPKNHKLE_01451 0.0 mco Q Multicopper oxidase
BPKNHKLE_01452 2.8e-51 K 2 iron, 2 sulfur cluster binding
BPKNHKLE_01453 8.6e-91 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
BPKNHKLE_01454 6.3e-120 Q Methyltransferase domain
BPKNHKLE_01456 2.3e-102 S CAAX protease self-immunity
BPKNHKLE_01457 5.4e-100 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BPKNHKLE_01458 1.7e-39 fsr EGP Major Facilitator Superfamily
BPKNHKLE_01459 8.5e-74 fsr EGP Major Facilitator Superfamily
BPKNHKLE_01460 1.4e-101 K helix_turn_helix multiple antibiotic resistance protein
BPKNHKLE_01461 1.3e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
BPKNHKLE_01462 1.6e-105
BPKNHKLE_01463 2e-85 dps P Belongs to the Dps family
BPKNHKLE_01464 8.2e-304 ybiT S ABC transporter, ATP-binding protein
BPKNHKLE_01465 7.5e-20 L Transposase and inactivated derivatives IS30 family
BPKNHKLE_01466 2.9e-235 kgtP EGP Sugar (and other) transporter
BPKNHKLE_01467 5.4e-141 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
BPKNHKLE_01468 7.5e-153 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BPKNHKLE_01469 6.3e-149 isdE P Periplasmic binding protein
BPKNHKLE_01470 1e-94 M Iron Transport-associated domain
BPKNHKLE_01471 3.4e-269 isdH M Iron Transport-associated domain
BPKNHKLE_01472 1.3e-45
BPKNHKLE_01473 1.5e-53 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BPKNHKLE_01474 3.9e-31 ydzE EG spore germination
BPKNHKLE_01475 3.1e-93 P Cadmium resistance transporter
BPKNHKLE_01476 1.7e-134 IQ Dehydrogenase reductase
BPKNHKLE_01477 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
BPKNHKLE_01478 2.5e-161 EG EamA-like transporter family
BPKNHKLE_01479 0.0 helD 3.6.4.12 L DNA helicase
BPKNHKLE_01480 1.6e-117 dedA S SNARE associated Golgi protein
BPKNHKLE_01481 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
BPKNHKLE_01482 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BPKNHKLE_01483 1.4e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPKNHKLE_01484 1.1e-178 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPKNHKLE_01485 7e-36 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
BPKNHKLE_01486 3e-85 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
BPKNHKLE_01487 2.8e-63 pucR QT Purine catabolism regulatory protein-like family
BPKNHKLE_01488 3.9e-129 allB 3.5.2.5 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
BPKNHKLE_01489 1.7e-98 allC 3.5.1.6, 3.5.1.87, 3.5.3.9 E Peptidase family M20/M25/M40
BPKNHKLE_01490 7.7e-202 allD 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
BPKNHKLE_01491 1.2e-11 sucD 6.2.1.5 C CoA-ligase
BPKNHKLE_01492 1.3e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
BPKNHKLE_01493 3e-124 C nitroreductase
BPKNHKLE_01494 4.6e-137 E GDSL-like Lipase/Acylhydrolase family
BPKNHKLE_01495 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
BPKNHKLE_01496 1.3e-307 recN L May be involved in recombinational repair of damaged DNA
BPKNHKLE_01497 6.2e-76 argR K Regulates arginine biosynthesis genes
BPKNHKLE_01498 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
BPKNHKLE_01499 9.6e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
BPKNHKLE_01500 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BPKNHKLE_01501 6.1e-258 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BPKNHKLE_01502 1e-159 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BPKNHKLE_01503 8.9e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BPKNHKLE_01504 9e-72 yqhY S Asp23 family, cell envelope-related function
BPKNHKLE_01505 4e-206 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
BPKNHKLE_01506 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
BPKNHKLE_01507 9e-53 ysxB J Cysteine protease Prp
BPKNHKLE_01508 1.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
BPKNHKLE_01509 9.6e-115 K Transcriptional regulator
BPKNHKLE_01511 6.6e-93 dut S Protein conserved in bacteria
BPKNHKLE_01512 2.3e-176
BPKNHKLE_01513 7e-148
BPKNHKLE_01514 4.7e-13
BPKNHKLE_01515 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
BPKNHKLE_01516 8.5e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BPKNHKLE_01517 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
BPKNHKLE_01518 1.5e-71 yqhL P Rhodanese-like protein
BPKNHKLE_01519 1.2e-180 glk 2.7.1.2 G Glucokinase
BPKNHKLE_01520 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
BPKNHKLE_01521 6.9e-116 gluP 3.4.21.105 S Peptidase, S54 family
BPKNHKLE_01522 9.2e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BPKNHKLE_01523 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BPKNHKLE_01524 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
BPKNHKLE_01525 0.0 S membrane
BPKNHKLE_01526 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BPKNHKLE_01527 3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
BPKNHKLE_01528 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BPKNHKLE_01529 5.1e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BPKNHKLE_01530 8.6e-59 yodB K Transcriptional regulator, HxlR family
BPKNHKLE_01531 7.8e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
BPKNHKLE_01532 3.4e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BPKNHKLE_01533 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
BPKNHKLE_01534 7.2e-132 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BPKNHKLE_01535 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
BPKNHKLE_01536 1.6e-233 V MatE
BPKNHKLE_01537 2e-280 arlS 2.7.13.3 T Histidine kinase
BPKNHKLE_01538 5.6e-121 K response regulator
BPKNHKLE_01539 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
BPKNHKLE_01540 4.6e-97 yceD S Uncharacterized ACR, COG1399
BPKNHKLE_01541 9.3e-214 ylbM S Belongs to the UPF0348 family
BPKNHKLE_01542 8.3e-142 yqeM Q Methyltransferase
BPKNHKLE_01543 6.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
BPKNHKLE_01544 7.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
BPKNHKLE_01545 4.1e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BPKNHKLE_01546 2.6e-49 yhbY J RNA-binding protein
BPKNHKLE_01547 2.6e-216 yqeH S Ribosome biogenesis GTPase YqeH
BPKNHKLE_01548 2.2e-96 yqeG S HAD phosphatase, family IIIA
BPKNHKLE_01549 9.7e-24 yoaK S Protein of unknown function (DUF1275)
BPKNHKLE_01550 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BPKNHKLE_01551 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
BPKNHKLE_01552 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BPKNHKLE_01553 2.5e-172 dnaI L Primosomal protein DnaI
BPKNHKLE_01554 3e-251 dnaB L replication initiation and membrane attachment
BPKNHKLE_01555 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BPKNHKLE_01556 1e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BPKNHKLE_01557 2.1e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
BPKNHKLE_01558 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BPKNHKLE_01559 6.5e-139 aroD S Serine hydrolase (FSH1)
BPKNHKLE_01560 1.8e-114 ybhL S Belongs to the BI1 family
BPKNHKLE_01561 5.5e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
BPKNHKLE_01562 2e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BPKNHKLE_01563 3.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
BPKNHKLE_01564 5.1e-59 ytzB S Small secreted protein
BPKNHKLE_01565 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
BPKNHKLE_01566 3.8e-210 ecsB U ABC transporter
BPKNHKLE_01567 2.3e-133 ecsA V ABC transporter, ATP-binding protein
BPKNHKLE_01568 1.4e-77 hit FG histidine triad
BPKNHKLE_01570 3.1e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
BPKNHKLE_01571 5.7e-180 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
BPKNHKLE_01572 9.8e-56 yheA S Belongs to the UPF0342 family
BPKNHKLE_01573 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BPKNHKLE_01574 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
BPKNHKLE_01576 1.7e-36
BPKNHKLE_01578 2.4e-201 folP 2.5.1.15 H dihydropteroate synthase
BPKNHKLE_01579 1.2e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
BPKNHKLE_01580 1.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BPKNHKLE_01581 3.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
BPKNHKLE_01582 8.4e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
BPKNHKLE_01583 2.5e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BPKNHKLE_01584 2e-118 S CAAX protease self-immunity
BPKNHKLE_01585 9.9e-183 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
BPKNHKLE_01586 3.6e-111
BPKNHKLE_01587 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
BPKNHKLE_01588 3.9e-164 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
BPKNHKLE_01589 3.2e-256 S Putative peptidoglycan binding domain
BPKNHKLE_01590 5.5e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPKNHKLE_01591 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BPKNHKLE_01592 3.2e-102
BPKNHKLE_01593 9.5e-26
BPKNHKLE_01594 6.3e-171 scrR K Transcriptional regulator, LacI family
BPKNHKLE_01595 2.1e-171 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
BPKNHKLE_01596 1e-45 czrA K Transcriptional regulator, ArsR family
BPKNHKLE_01597 1.8e-75 argR K Regulates arginine biosynthesis genes
BPKNHKLE_01598 1.4e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
BPKNHKLE_01599 5e-158 hrtB V ABC transporter permease
BPKNHKLE_01600 1.1e-107 ygfC K Bacterial regulatory proteins, tetR family
BPKNHKLE_01601 7.9e-70 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
BPKNHKLE_01602 8.4e-22 M Glycosyltransferase like family 2
BPKNHKLE_01603 3.8e-117 yecS E ABC transporter permease
BPKNHKLE_01604 1e-156 yckB ET Belongs to the bacterial solute-binding protein 3 family
BPKNHKLE_01605 9.7e-109 XK27_02070 S Nitroreductase family
BPKNHKLE_01606 5.3e-71 rnhA 3.1.26.4 L Ribonuclease HI
BPKNHKLE_01607 1.7e-70 esbA S Family of unknown function (DUF5322)
BPKNHKLE_01608 3e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BPKNHKLE_01609 1e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BPKNHKLE_01610 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
BPKNHKLE_01611 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
BPKNHKLE_01612 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
BPKNHKLE_01613 4.2e-29 EGP Major facilitator Superfamily
BPKNHKLE_01614 0.0 copA 3.6.3.54 P P-type ATPase
BPKNHKLE_01615 2.3e-40 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
BPKNHKLE_01616 1.1e-46 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
BPKNHKLE_01617 1.6e-177
BPKNHKLE_01618 1e-223 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
BPKNHKLE_01619 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BPKNHKLE_01620 5.8e-241 purD 6.3.4.13 F Belongs to the GARS family
BPKNHKLE_01621 2.8e-86 S Protein of unknown function (DUF3644)
BPKNHKLE_01622 5.8e-44 3.4.21.88 K Helix-turn-helix domain
BPKNHKLE_01623 1.1e-15 K Helix-turn-helix XRE-family like proteins
BPKNHKLE_01624 8.9e-147 K Phage regulatory protein
BPKNHKLE_01628 7.2e-10 S Domain of unknown function (DUF771)
BPKNHKLE_01634 3.8e-93 recT L RecT family
BPKNHKLE_01635 1.5e-33 recT L RecT family
BPKNHKLE_01636 4.5e-152 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
BPKNHKLE_01637 2e-94 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BPKNHKLE_01638 1.4e-26 L Psort location Cytoplasmic, score
BPKNHKLE_01641 6.9e-200 S Domain of unknown function (DUF4432)
BPKNHKLE_01642 1.7e-114 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BPKNHKLE_01643 3.7e-171 deoR K sugar-binding domain protein
BPKNHKLE_01644 2.2e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BPKNHKLE_01645 2.1e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
BPKNHKLE_01646 2.7e-244 fucP G Major Facilitator Superfamily
BPKNHKLE_01647 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BPKNHKLE_01648 2.5e-75 S Core-2/I-Branching enzyme
BPKNHKLE_01649 4.7e-36 S Acyltransferase family
BPKNHKLE_01650 2.8e-93 S Cupin superfamily (DUF985)
BPKNHKLE_01651 1e-122 K response regulator
BPKNHKLE_01652 1e-207 hpk31 2.7.13.3 T Histidine kinase
BPKNHKLE_01653 2.6e-204 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BPKNHKLE_01654 7.6e-139 azlC E AzlC protein
BPKNHKLE_01655 1.2e-60 azlD S branched-chain amino acid
BPKNHKLE_01656 7e-124 K Crp-like helix-turn-helix domain
BPKNHKLE_01657 3.6e-241 larA 5.1.2.1 S Domain of unknown function (DUF2088)
BPKNHKLE_01658 1.7e-131 cpmA S AIR carboxylase
BPKNHKLE_01659 9.2e-216 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BPKNHKLE_01660 7.6e-129 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
BPKNHKLE_01661 6.5e-148 larE S NAD synthase
BPKNHKLE_01662 6.2e-185 hoxN U High-affinity nickel-transport protein
BPKNHKLE_01663 5.4e-253 G Major Facilitator
BPKNHKLE_01664 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
BPKNHKLE_01665 1.6e-177 K Transcriptional regulator, LacI family
BPKNHKLE_01666 5.4e-157 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
BPKNHKLE_01667 4.6e-09
BPKNHKLE_01668 2.7e-224 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
BPKNHKLE_01669 2.7e-53 S Protein of unknown function (DUF3644)
BPKNHKLE_01670 1.1e-21 E Zn peptidase
BPKNHKLE_01671 2e-23
BPKNHKLE_01672 3.7e-129 S Domain of unknown function (DUF4393)
BPKNHKLE_01674 8.9e-58
BPKNHKLE_01675 3.3e-200 L Belongs to the 'phage' integrase family
BPKNHKLE_01677 2.1e-90
BPKNHKLE_01678 3.8e-78 F Nucleoside 2-deoxyribosyltransferase
BPKNHKLE_01679 6.7e-184 scrR3 K Transcriptional regulator, LacI family
BPKNHKLE_01680 6.8e-13
BPKNHKLE_01681 1.7e-161 hrtB V ABC transporter permease
BPKNHKLE_01682 5.3e-116 devA 3.6.3.25 V ABC transporter, ATP-binding protein
BPKNHKLE_01683 4.5e-103 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
BPKNHKLE_01684 1.9e-74 K Copper transport repressor CopY TcrY
BPKNHKLE_01685 0.0 copB 3.6.3.4 P P-type ATPase
BPKNHKLE_01687 1.2e-251 mntH P H( )-stimulated, divalent metal cation uptake system
BPKNHKLE_01688 1.5e-21
BPKNHKLE_01689 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BPKNHKLE_01690 4.1e-70 L nuclease
BPKNHKLE_01691 4.2e-161 F DNA/RNA non-specific endonuclease
BPKNHKLE_01692 1.6e-111 lepB 3.4.21.89 U Belongs to the peptidase S26 family
BPKNHKLE_01693 1.7e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BPKNHKLE_01694 7.5e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BPKNHKLE_01695 0.0 asnB 6.3.5.4 E Asparagine synthase
BPKNHKLE_01696 1.5e-219 lysP E amino acid
BPKNHKLE_01697 7.8e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
BPKNHKLE_01698 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
BPKNHKLE_01699 1.1e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BPKNHKLE_01700 2.1e-146 jag S R3H domain protein
BPKNHKLE_01701 3.4e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BPKNHKLE_01702 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
BPKNHKLE_01703 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
BPKNHKLE_01705 1.4e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BPKNHKLE_01706 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
BPKNHKLE_01707 2.2e-34 yaaA S S4 domain protein YaaA
BPKNHKLE_01708 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BPKNHKLE_01709 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BPKNHKLE_01710 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BPKNHKLE_01711 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
BPKNHKLE_01712 6.4e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BPKNHKLE_01713 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BPKNHKLE_01714 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
BPKNHKLE_01715 1.2e-74 rplI J Binds to the 23S rRNA
BPKNHKLE_01716 6.3e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
BPKNHKLE_01717 1.4e-207 lmrP E Major Facilitator Superfamily
BPKNHKLE_01718 1.8e-49
BPKNHKLE_01721 6.8e-130 K response regulator
BPKNHKLE_01722 0.0 vicK 2.7.13.3 T Histidine kinase
BPKNHKLE_01723 3.3e-239 yycH S YycH protein
BPKNHKLE_01724 2.7e-143 yycI S YycH protein
BPKNHKLE_01725 6e-154 vicX 3.1.26.11 S domain protein
BPKNHKLE_01726 3e-208 htrA 3.4.21.107 O serine protease
BPKNHKLE_01727 4.4e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BPKNHKLE_01728 5.7e-71 K Transcriptional regulator
BPKNHKLE_01729 3.2e-175 malR K Transcriptional regulator, LacI family
BPKNHKLE_01730 1.1e-250 malT G Major Facilitator
BPKNHKLE_01731 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
BPKNHKLE_01732 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
BPKNHKLE_01733 1.8e-15 natA S ABC transporter, ATP-binding protein
BPKNHKLE_01734 8.8e-16 natA S ABC transporter, ATP-binding protein
BPKNHKLE_01735 9e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
BPKNHKLE_01736 1.4e-183 D Alpha beta
BPKNHKLE_01737 4.1e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPKNHKLE_01738 7.2e-217 patA 2.6.1.1 E Aminotransferase
BPKNHKLE_01739 2.7e-35
BPKNHKLE_01740 0.0 clpL O associated with various cellular activities
BPKNHKLE_01741 1.8e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BPKNHKLE_01742 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
BPKNHKLE_01743 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
BPKNHKLE_01744 3.9e-105 yvgN C Aldo keto reductase
BPKNHKLE_01745 1.2e-38 yvgN C Aldo keto reductase
BPKNHKLE_01746 5e-293 glpQ 3.1.4.46 C phosphodiesterase
BPKNHKLE_01747 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
BPKNHKLE_01748 1.6e-189 ybhR V ABC transporter
BPKNHKLE_01749 6.6e-128 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
BPKNHKLE_01750 2.8e-42 K transcriptional regulator
BPKNHKLE_01751 1.1e-103 2.3.1.128 K acetyltransferase
BPKNHKLE_01752 5.9e-174 coaA 2.7.1.33 F Pantothenic acid kinase
BPKNHKLE_01753 4.9e-131 sptS 2.7.13.3 T Histidine kinase
BPKNHKLE_01754 8e-80 K response regulator
BPKNHKLE_01755 1e-113 2.7.6.5 T Region found in RelA / SpoT proteins
BPKNHKLE_01756 9e-268 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
BPKNHKLE_01757 1.8e-105 S polysaccharide biosynthetic process
BPKNHKLE_01758 3.2e-33 wcaB 2.3.1.30 E serine acetyltransferase
BPKNHKLE_01760 5.4e-48 S glycosyl transferase family 2
BPKNHKLE_01761 1.1e-52 MA20_43635 M Capsular polysaccharide synthesis protein
BPKNHKLE_01762 3.5e-66 M Domain of unknown function (DUF4422)
BPKNHKLE_01763 6.1e-29 S Domain of unknown function (DUF4767)
BPKNHKLE_01764 5.4e-44 S Tautomerase enzyme
BPKNHKLE_01765 2.1e-22 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
BPKNHKLE_01766 7.8e-120 pnb C nitroreductase
BPKNHKLE_01767 3.2e-83 S Alpha/beta hydrolase family
BPKNHKLE_01768 1.2e-79 S Belongs to the short-chain dehydrogenases reductases (SDR) family
BPKNHKLE_01769 6.2e-24 C reductase
BPKNHKLE_01770 7.7e-46 C Aldo keto reductase
BPKNHKLE_01774 1.2e-196 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
BPKNHKLE_01775 0.0 pepN 3.4.11.2 E aminopeptidase
BPKNHKLE_01776 1.7e-60 K Transcriptional regulator
BPKNHKLE_01777 1.3e-24 phaG GT1 I carboxylic ester hydrolase activity
BPKNHKLE_01778 8.1e-68 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
BPKNHKLE_01779 4.9e-63 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
BPKNHKLE_01781 5.5e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPKNHKLE_01782 7.5e-300 L Recombinase
BPKNHKLE_01783 0.0 L Recombinase zinc beta ribbon domain
BPKNHKLE_01784 8e-35
BPKNHKLE_01785 5.5e-145 M Glycosyl hydrolases family 25
BPKNHKLE_01786 3.6e-70 S Bacteriophage holin family
BPKNHKLE_01787 3.4e-67 S Phage head-tail joining protein
BPKNHKLE_01788 2.8e-42 S Phage gp6-like head-tail connector protein
BPKNHKLE_01789 4.1e-89 S Aminoacyl-tRNA editing domain
BPKNHKLE_01790 3.1e-75 ddaH 3.5.3.18 E Amidinotransferase
BPKNHKLE_01792 4.3e-192 nhaC C Na H antiporter NhaC
BPKNHKLE_01793 1.4e-185 S Phosphotransferase system, EIIC
BPKNHKLE_01794 4.6e-23 D mRNA cleavage
BPKNHKLE_01795 1.9e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
BPKNHKLE_01797 9e-40 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
BPKNHKLE_01798 6.7e-66 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
BPKNHKLE_01799 6.7e-49 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
BPKNHKLE_01800 6.8e-70 ydjP I Alpha/beta hydrolase family
BPKNHKLE_01801 4.4e-106 L Integrase
BPKNHKLE_01802 7.3e-38 M Protein of unknown function (DUF3737)
BPKNHKLE_01803 2.6e-30 4.4.1.8 E Aminotransferase, class I
BPKNHKLE_01804 1.5e-129 1.14.12.17 C Oxidoreductase NAD-binding domain
BPKNHKLE_01805 0.0 ubiB S ABC1 family
BPKNHKLE_01806 1.1e-103 wecD3 K Acetyltransferase (GNAT) family
BPKNHKLE_01807 1.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
BPKNHKLE_01808 2.2e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BPKNHKLE_01809 2.9e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BPKNHKLE_01810 5.4e-53
BPKNHKLE_01811 1.4e-43
BPKNHKLE_01812 2.8e-219 3.6.4.12 L DnaB-like helicase C terminal domain
BPKNHKLE_01814 2.1e-13
BPKNHKLE_01815 1.5e-225 aadAT EK Aminotransferase, class I
BPKNHKLE_01816 1.5e-81 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
BPKNHKLE_01817 5.2e-45 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
BPKNHKLE_01818 6.3e-143 ET Bacterial periplasmic substrate-binding proteins
BPKNHKLE_01819 1e-103 dedA S SNARE-like domain protein
BPKNHKLE_01820 1.4e-23 S Protein of unknown function (DUF1461)
BPKNHKLE_01821 6.6e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
BPKNHKLE_01822 2.2e-96 yutD S Protein of unknown function (DUF1027)
BPKNHKLE_01823 1.3e-58 S Calcineurin-like phosphoesterase
BPKNHKLE_01824 1.6e-38 S Calcineurin-like phosphoesterase
BPKNHKLE_01825 2.1e-224 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BPKNHKLE_01826 1e-159 ytxK 2.1.1.72 L N-6 DNA Methylase
BPKNHKLE_01828 5e-14
BPKNHKLE_01830 2.3e-15 NU general secretion pathway protein
BPKNHKLE_01831 1.1e-47 comGC U competence protein ComGC
BPKNHKLE_01832 5.6e-157 comGB NU type II secretion system
BPKNHKLE_01833 2.7e-177 comGA NU Type II IV secretion system protein
BPKNHKLE_01834 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
BPKNHKLE_01835 1.9e-83 mltD CBM50 M PFAM NLP P60 protein
BPKNHKLE_01836 3.7e-134 yebC K Transcriptional regulatory protein
BPKNHKLE_01837 3.6e-85
BPKNHKLE_01838 2.2e-185 ccpA K catabolite control protein A
BPKNHKLE_01839 4.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
BPKNHKLE_01840 4.9e-70
BPKNHKLE_01841 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BPKNHKLE_01842 2e-155 ykuT M mechanosensitive ion channel
BPKNHKLE_01843 1.7e-151 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
BPKNHKLE_01844 4.4e-94 S Phosphoesterase
BPKNHKLE_01845 3.6e-108 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BPKNHKLE_01846 6.3e-148 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
BPKNHKLE_01847 3e-93 yslB S Protein of unknown function (DUF2507)
BPKNHKLE_01848 1.2e-225 clcA_2 P Chloride transporter, ClC family
BPKNHKLE_01849 1e-53 trxA O Belongs to the thioredoxin family
BPKNHKLE_01850 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
BPKNHKLE_01851 4.7e-91 cvpA S Colicin V production protein
BPKNHKLE_01852 1.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BPKNHKLE_01853 5.7e-33 yrzB S Belongs to the UPF0473 family
BPKNHKLE_01854 9.6e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BPKNHKLE_01855 1.2e-42 yrzL S Belongs to the UPF0297 family
BPKNHKLE_01856 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BPKNHKLE_01857 4.2e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
BPKNHKLE_01858 3.4e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
BPKNHKLE_01859 5.5e-42 yajC U Preprotein translocase
BPKNHKLE_01860 2.2e-176 2.4.2.29 F queuine tRNA-ribosyltransferase activity
BPKNHKLE_01861 2.9e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
BPKNHKLE_01862 1.9e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
BPKNHKLE_01863 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BPKNHKLE_01864 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BPKNHKLE_01865 8.4e-205 rny S Endoribonuclease that initiates mRNA decay
BPKNHKLE_01866 1.1e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BPKNHKLE_01867 5.4e-231 cinA 3.5.1.42 S Belongs to the CinA family
BPKNHKLE_01868 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BPKNHKLE_01869 1.8e-96 ymfM S Helix-turn-helix domain
BPKNHKLE_01870 1.7e-251 ymfH S Peptidase M16
BPKNHKLE_01871 1.5e-231 ymfF S Peptidase M16 inactive domain protein
BPKNHKLE_01872 2.4e-161 aatB ET ABC transporter substrate-binding protein
BPKNHKLE_01873 4.8e-114 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
BPKNHKLE_01874 1.4e-108 glnP P ABC transporter permease
BPKNHKLE_01875 6.6e-93 mreD M rod shape-determining protein MreD
BPKNHKLE_01876 1.4e-145 mreC M Involved in formation and maintenance of cell shape
BPKNHKLE_01877 1.9e-181 mreB D cell shape determining protein MreB
BPKNHKLE_01878 3.3e-115 radC L DNA repair protein
BPKNHKLE_01879 1.9e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BPKNHKLE_01880 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
BPKNHKLE_01881 1.6e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BPKNHKLE_01884 4.1e-90 L Probable transposase
BPKNHKLE_01885 3e-28 EGP Major Facilitator Superfamily
BPKNHKLE_01886 1.6e-44 EGP Major Facilitator Superfamily
BPKNHKLE_01887 1.6e-69 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
BPKNHKLE_01888 6.9e-58 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
BPKNHKLE_01889 3.5e-15 C Flavodoxin
BPKNHKLE_01890 4.3e-27 GM NmrA-like family
BPKNHKLE_01891 5.1e-19 S NAD(P)H dehydrogenase (quinone) activity
BPKNHKLE_01892 1.4e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPKNHKLE_01893 9.8e-77
BPKNHKLE_01894 1.6e-102 gbuC E glycine betaine
BPKNHKLE_01895 4.8e-98 proW E glycine betaine
BPKNHKLE_01896 1.1e-153 gbuA 3.6.1.1, 3.6.3.32 E glycine betaine
BPKNHKLE_01897 5.4e-214 2.1.1.14 E methionine synthase, vitamin-B12 independent
BPKNHKLE_01898 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
BPKNHKLE_01899 3.5e-38 S Cytochrome B5
BPKNHKLE_01900 1.7e-14 yfjR K Psort location Cytoplasmic, score
BPKNHKLE_01902 6.5e-11 S Domain of unknown function (DUF4811)
BPKNHKLE_01903 8.7e-40 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPKNHKLE_01904 8.9e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
BPKNHKLE_01905 4.3e-217 yceI EGP Major facilitator Superfamily
BPKNHKLE_01906 2.6e-54 tnp2PF3 L Transposase
BPKNHKLE_01907 8.3e-33 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
BPKNHKLE_01908 4.1e-21 L Transposase
BPKNHKLE_01909 4.1e-113 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
BPKNHKLE_01910 1.6e-45 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
BPKNHKLE_01911 5.6e-33 copZ P Heavy-metal-associated domain
BPKNHKLE_01912 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
BPKNHKLE_01913 1.2e-64
BPKNHKLE_01914 6.3e-140 L reverse transcriptase
BPKNHKLE_01915 1.4e-189 L Transposase and inactivated derivatives, IS30 family
BPKNHKLE_01916 4.1e-19
BPKNHKLE_01917 9.8e-30
BPKNHKLE_01918 4.4e-42 S dextransucrase activity
BPKNHKLE_01919 2.4e-192 yegU O ADP-ribosylglycohydrolase
BPKNHKLE_01920 2.3e-251 F Belongs to the purine-cytosine permease (2.A.39) family
BPKNHKLE_01921 7.2e-169 G Belongs to the carbohydrate kinase PfkB family
BPKNHKLE_01922 8.2e-48 L Transposase DDE domain group 1
BPKNHKLE_01924 4.6e-40
BPKNHKLE_01925 1.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
BPKNHKLE_01926 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BPKNHKLE_01927 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
BPKNHKLE_01928 6.4e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BPKNHKLE_01929 4.8e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BPKNHKLE_01931 5.5e-26 S YjcQ protein
BPKNHKLE_01932 1.3e-148 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
BPKNHKLE_01933 5.3e-133 S Membrane
BPKNHKLE_01934 1.3e-75 4.4.1.5 E Glyoxalase
BPKNHKLE_01935 4.5e-85 yueI S Protein of unknown function (DUF1694)
BPKNHKLE_01936 4.9e-235 rarA L recombination factor protein RarA
BPKNHKLE_01938 2.3e-81 usp6 T universal stress protein
BPKNHKLE_01939 8.4e-151 2.3.1.19 K Helix-turn-helix XRE-family like proteins
BPKNHKLE_01940 7.7e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
BPKNHKLE_01941 5.8e-180 S Protein of unknown function (DUF2785)
BPKNHKLE_01943 5.8e-222 rodA D Belongs to the SEDS family
BPKNHKLE_01944 7.9e-32 S Protein of unknown function (DUF2969)
BPKNHKLE_01945 2.6e-183 mbl D Cell shape determining protein MreB Mrl
BPKNHKLE_01946 1.9e-220 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
BPKNHKLE_01947 2.8e-29 S Protein of unknown function (DUF1146)
BPKNHKLE_01948 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
BPKNHKLE_01949 4.4e-253 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BPKNHKLE_01950 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BPKNHKLE_01951 2.1e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BPKNHKLE_01952 7.4e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BPKNHKLE_01953 2.6e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BPKNHKLE_01954 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BPKNHKLE_01955 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
BPKNHKLE_01956 5.4e-218 pyrP F Permease
BPKNHKLE_01957 4.2e-125 yibF S overlaps another CDS with the same product name
BPKNHKLE_01958 1.7e-183 yibE S overlaps another CDS with the same product name
BPKNHKLE_01959 1.2e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BPKNHKLE_01960 1.7e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BPKNHKLE_01961 9.8e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
BPKNHKLE_01962 3.2e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
BPKNHKLE_01963 2.5e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BPKNHKLE_01964 3.2e-109 tdk 2.7.1.21 F thymidine kinase
BPKNHKLE_01965 3.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
BPKNHKLE_01966 1.3e-139 cobQ S CobB/CobQ-like glutamine amidotransferase domain
BPKNHKLE_01967 2.8e-48
BPKNHKLE_01968 1.9e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BPKNHKLE_01969 2.8e-193 ampC V Beta-lactamase
BPKNHKLE_01970 0.0 yfiC V ABC transporter
BPKNHKLE_01971 0.0 lmrA V ABC transporter, ATP-binding protein
BPKNHKLE_01972 1.8e-78 K Winged helix DNA-binding domain
BPKNHKLE_01973 2.3e-07
BPKNHKLE_01975 1e-56
BPKNHKLE_01977 2.1e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
BPKNHKLE_01978 1.7e-145 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BPKNHKLE_01979 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
BPKNHKLE_01980 1.8e-122 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
BPKNHKLE_01981 1.6e-85 K GNAT family
BPKNHKLE_01983 5.2e-35 L Transposase and inactivated derivatives, IS30 family
BPKNHKLE_01984 1.2e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
BPKNHKLE_01985 0.0 cadA 3.6.3.3, 3.6.3.5 P Cadmium transporter
BPKNHKLE_01986 1.3e-162 L Transposase and inactivated derivatives, IS30 family
BPKNHKLE_01987 6.2e-218 lacS G Transporter
BPKNHKLE_01988 2.3e-83 lacR K Transcriptional regulator
BPKNHKLE_01989 7.7e-171 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
BPKNHKLE_01990 1.9e-224 emrY EGP Major facilitator Superfamily
BPKNHKLE_01991 2.1e-61 3.2.1.23 S Domain of unknown function DUF302
BPKNHKLE_01992 9.8e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BPKNHKLE_01993 1.1e-272 pepV 3.5.1.18 E dipeptidase PepV
BPKNHKLE_01994 5.1e-87 uspA T Belongs to the universal stress protein A family
BPKNHKLE_01995 1.3e-170 L Integrase core domain
BPKNHKLE_01997 6.3e-271 nylA 3.5.1.4 J Belongs to the amidase family
BPKNHKLE_01998 5.5e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPKNHKLE_01999 1.3e-75 S Homeodomain-like domain
BPKNHKLE_02001 5.9e-98 D Cellulose biosynthesis protein BcsQ
BPKNHKLE_02002 2.7e-97 xerC L Phage integrase, N-terminal SAM-like domain
BPKNHKLE_02004 2.6e-255 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
BPKNHKLE_02005 1.3e-31 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
BPKNHKLE_02006 4.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BPKNHKLE_02007 5e-162 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
BPKNHKLE_02008 3e-184 fruR3 K Transcriptional regulator, LacI family
BPKNHKLE_02009 1.9e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
BPKNHKLE_02010 8.9e-83 F Hydrolase, NUDIX family
BPKNHKLE_02011 1.4e-212 S Type IV secretion-system coupling protein DNA-binding domain
BPKNHKLE_02012 0.0 tetP J elongation factor G
BPKNHKLE_02013 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
BPKNHKLE_02014 2.7e-111 ypsA S Belongs to the UPF0398 family
BPKNHKLE_02015 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
BPKNHKLE_02016 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
BPKNHKLE_02017 3.7e-160 EG EamA-like transporter family
BPKNHKLE_02018 1.8e-192 C Aldo keto reductase family protein
BPKNHKLE_02019 1.3e-121 ypuA S Protein of unknown function (DUF1002)
BPKNHKLE_02020 4.7e-134 dnaD L DnaD domain protein
BPKNHKLE_02021 1.7e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
BPKNHKLE_02022 1.6e-88 ypmB S Protein conserved in bacteria
BPKNHKLE_02023 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
BPKNHKLE_02024 2.2e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
BPKNHKLE_02025 2.4e-181 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
BPKNHKLE_02026 1.5e-211 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
BPKNHKLE_02027 4.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
BPKNHKLE_02028 1.5e-93 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
BPKNHKLE_02029 2.3e-103 pstA P Phosphate transport system permease protein PstA
BPKNHKLE_02031 1.8e-75 pstC P probably responsible for the translocation of the substrate across the membrane
BPKNHKLE_02032 9e-92 pstS P Phosphate
BPKNHKLE_02033 2.4e-272 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
BPKNHKLE_02034 4.5e-154 yitU 3.1.3.104 S hydrolase
BPKNHKLE_02035 4.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
BPKNHKLE_02036 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
BPKNHKLE_02037 8.7e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
BPKNHKLE_02038 1.6e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
BPKNHKLE_02039 3.3e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
BPKNHKLE_02040 6.6e-56 ycsI S Protein of unknown function (DUF1445)
BPKNHKLE_02041 2e-84 L Belongs to the 'phage' integrase family
BPKNHKLE_02042 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
BPKNHKLE_02043 1.3e-260 yfnA E Amino Acid
BPKNHKLE_02044 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
BPKNHKLE_02045 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BPKNHKLE_02046 3.5e-39 ylqC S Belongs to the UPF0109 family
BPKNHKLE_02047 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
BPKNHKLE_02048 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
BPKNHKLE_02049 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BPKNHKLE_02050 5.5e-153 pstA P Phosphate transport system permease protein PstA
BPKNHKLE_02051 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
BPKNHKLE_02052 5.1e-159 pstS P Phosphate
BPKNHKLE_02053 9.8e-129 K Transcriptional regulatory protein, C-terminal domain protein
BPKNHKLE_02054 1.7e-23
BPKNHKLE_02055 7.6e-108 T Calcineurin-like phosphoesterase superfamily domain
BPKNHKLE_02056 4.1e-213 G Major Facilitator Superfamily
BPKNHKLE_02057 1e-120 mleP3 S Membrane transport protein
BPKNHKLE_02058 1.1e-52 trxA O Belongs to the thioredoxin family
BPKNHKLE_02059 4.4e-255 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
BPKNHKLE_02060 1e-183 EG GntP family permease
BPKNHKLE_02061 2.3e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
BPKNHKLE_02062 0.0 trxB2 1.8.1.9 C Thioredoxin domain
BPKNHKLE_02063 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
BPKNHKLE_02064 2.2e-36 tnp L MULE transposase domain
BPKNHKLE_02065 1.5e-46 ubiE Q Methyltransferase domain
BPKNHKLE_02066 1.2e-21
BPKNHKLE_02067 2.9e-50 4.4.1.8 E Aminotransferase, class I
BPKNHKLE_02068 2e-34 4.4.1.8 E Aminotransferase, class I
BPKNHKLE_02069 1.4e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BPKNHKLE_02070 2.4e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BPKNHKLE_02072 3.6e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
BPKNHKLE_02073 3.5e-83 glcU U sugar transport
BPKNHKLE_02074 3.5e-87 galR K Transcriptional regulator
BPKNHKLE_02075 4.1e-21 L Transposase
BPKNHKLE_02076 9.5e-72 macB_3 V FtsX-like permease family
BPKNHKLE_02077 1.6e-90 S PAS domain
BPKNHKLE_02078 2.2e-30 E IrrE N-terminal-like domain
BPKNHKLE_02079 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
BPKNHKLE_02080 2.2e-45 IQ reductase
BPKNHKLE_02081 2e-11 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BPKNHKLE_02082 1.4e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)