ORF_ID e_value Gene_name EC_number CAZy COGs Description
HCMIEIIC_00001 7.9e-17 L Transposase DDE domain
HCMIEIIC_00002 3.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HCMIEIIC_00003 2.6e-197 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HCMIEIIC_00004 4.5e-29
HCMIEIIC_00006 3.4e-194 M Glycosyltransferase like family 2
HCMIEIIC_00007 2.2e-159 map 3.4.11.18 E Methionine Aminopeptidase
HCMIEIIC_00008 1.9e-80 fld C Flavodoxin
HCMIEIIC_00009 5.1e-179 yihY S Belongs to the UPF0761 family
HCMIEIIC_00010 1.2e-260 S Uncharacterized protein conserved in bacteria (DUF2252)
HCMIEIIC_00013 8.1e-109 K Bacterial regulatory proteins, tetR family
HCMIEIIC_00014 1.7e-237 pepS E Thermophilic metalloprotease (M29)
HCMIEIIC_00015 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HCMIEIIC_00016 2.6e-07
HCMIEIIC_00018 3.3e-71 S Domain of unknown function (DUF3284)
HCMIEIIC_00019 6.8e-48 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HCMIEIIC_00020 1.3e-227 yfmL 3.6.4.13 L DEAD DEAH box helicase
HCMIEIIC_00021 2.6e-177 mocA S Oxidoreductase
HCMIEIIC_00022 2e-61 S Domain of unknown function (DUF4828)
HCMIEIIC_00023 1.1e-59 S Protein of unknown function (DUF1093)
HCMIEIIC_00024 2e-132 lys M Glycosyl hydrolases family 25
HCMIEIIC_00025 3.2e-29
HCMIEIIC_00026 5e-120 qmcA O prohibitin homologues
HCMIEIIC_00027 4e-164 degV S Uncharacterised protein, DegV family COG1307
HCMIEIIC_00028 6e-79 K Acetyltransferase (GNAT) domain
HCMIEIIC_00029 0.0 pepO 3.4.24.71 O Peptidase family M13
HCMIEIIC_00030 1.2e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HCMIEIIC_00031 3.5e-146 cof S Sucrose-6F-phosphate phosphohydrolase
HCMIEIIC_00032 4.7e-216 yttB EGP Major facilitator Superfamily
HCMIEIIC_00033 5.7e-250 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCMIEIIC_00034 2.9e-193 yegS 2.7.1.107 G Lipid kinase
HCMIEIIC_00035 6.1e-279 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCMIEIIC_00036 8.8e-265 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCMIEIIC_00037 4.9e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCMIEIIC_00038 6.8e-204 camS S sex pheromone
HCMIEIIC_00039 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCMIEIIC_00040 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HCMIEIIC_00041 2.4e-45 yjgN S Bacterial protein of unknown function (DUF898)
HCMIEIIC_00042 6.2e-108 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HCMIEIIC_00043 1.5e-185 S response to antibiotic
HCMIEIIC_00045 3.8e-251 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HCMIEIIC_00046 5.3e-59
HCMIEIIC_00047 3.8e-82
HCMIEIIC_00048 5.2e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
HCMIEIIC_00049 7.6e-31
HCMIEIIC_00050 1.3e-93 yhbS S acetyltransferase
HCMIEIIC_00051 2.4e-273 yclK 2.7.13.3 T Histidine kinase
HCMIEIIC_00052 3.1e-133 K response regulator
HCMIEIIC_00053 1.7e-69 S SdpI/YhfL protein family
HCMIEIIC_00055 5.8e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCMIEIIC_00056 2.2e-14 ytgB S Transglycosylase associated protein
HCMIEIIC_00057 2.9e-16
HCMIEIIC_00058 1.4e-12 S Phage head-tail joining protein
HCMIEIIC_00059 5.1e-47 S Phage gp6-like head-tail connector protein
HCMIEIIC_00060 1.4e-268 S Phage capsid family
HCMIEIIC_00061 5.9e-219 S Phage portal protein
HCMIEIIC_00062 1.1e-20
HCMIEIIC_00063 0.0 terL S overlaps another CDS with the same product name
HCMIEIIC_00064 2.8e-79 terS L Phage terminase, small subunit
HCMIEIIC_00066 3e-270 S Virulence-associated protein E
HCMIEIIC_00067 9.4e-155 L Bifunctional DNA primase/polymerase, N-terminal
HCMIEIIC_00068 1.3e-24
HCMIEIIC_00069 2.7e-35
HCMIEIIC_00070 7.9e-11
HCMIEIIC_00071 1.1e-30
HCMIEIIC_00072 7e-43
HCMIEIIC_00073 2.3e-08 K Cro/C1-type HTH DNA-binding domain
HCMIEIIC_00075 1.4e-212 sip L Belongs to the 'phage' integrase family
HCMIEIIC_00076 0.0 rafA 3.2.1.22 G alpha-galactosidase
HCMIEIIC_00077 2.9e-162 arbZ I Phosphate acyltransferases
HCMIEIIC_00078 2.2e-179 arbY M family 8
HCMIEIIC_00079 2.1e-162 arbx M Glycosyl transferase family 8
HCMIEIIC_00080 5.8e-143 arbV 2.3.1.51 I Phosphate acyltransferases
HCMIEIIC_00081 1.2e-247 cycA E Amino acid permease
HCMIEIIC_00082 1.3e-73
HCMIEIIC_00083 7.6e-183 ytxK 2.1.1.72 L N-6 DNA Methylase
HCMIEIIC_00084 4.6e-49
HCMIEIIC_00085 1.1e-80
HCMIEIIC_00086 1.1e-47
HCMIEIIC_00088 5.1e-48
HCMIEIIC_00089 7.5e-164 comGB NU type II secretion system
HCMIEIIC_00090 1.3e-133 comGA NU Type II IV secretion system protein
HCMIEIIC_00091 9.9e-132 yebC K Transcriptional regulatory protein
HCMIEIIC_00092 3.3e-91 S VanZ like family
HCMIEIIC_00093 0.0 pepF2 E Oligopeptidase F
HCMIEIIC_00094 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCMIEIIC_00095 9.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCMIEIIC_00096 1.5e-168 ybbR S YbbR-like protein
HCMIEIIC_00097 1e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCMIEIIC_00098 8.1e-126 V AAA domain, putative AbiEii toxin, Type IV TA system
HCMIEIIC_00099 5.4e-177 V ABC transporter
HCMIEIIC_00100 2.2e-117 K Transcriptional regulator
HCMIEIIC_00101 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HCMIEIIC_00103 1.1e-59
HCMIEIIC_00104 1.1e-80 S Domain of unknown function (DUF5067)
HCMIEIIC_00105 1.6e-207 potD P ABC transporter
HCMIEIIC_00106 8.9e-145 potC P ABC transporter permease
HCMIEIIC_00107 3.8e-148 potB P ABC transporter permease
HCMIEIIC_00108 4.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCMIEIIC_00109 2.9e-96 puuR K Cupin domain
HCMIEIIC_00110 0.0 yjcE P Sodium proton antiporter
HCMIEIIC_00111 2.6e-166 murB 1.3.1.98 M Cell wall formation
HCMIEIIC_00112 1.9e-149 xth 3.1.11.2 L exodeoxyribonuclease III
HCMIEIIC_00113 3.1e-98 dnaQ 2.7.7.7 L DNA polymerase III
HCMIEIIC_00114 4.8e-219 ysdA CP ABC-2 family transporter protein
HCMIEIIC_00115 5.4e-164 natA S ABC transporter, ATP-binding protein
HCMIEIIC_00116 4.6e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HCMIEIIC_00117 8.4e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HCMIEIIC_00118 4.6e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCMIEIIC_00119 2e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
HCMIEIIC_00120 9e-92 yxjI
HCMIEIIC_00121 4.4e-103 3.2.2.20 K Acetyltransferase (GNAT) domain
HCMIEIIC_00122 1.7e-193 malK P ATPases associated with a variety of cellular activities
HCMIEIIC_00123 2.6e-166 malG P ABC-type sugar transport systems, permease components
HCMIEIIC_00124 1.6e-146 malF G Binding-protein-dependent transport system inner membrane component
HCMIEIIC_00125 4.4e-239 malE G Bacterial extracellular solute-binding protein
HCMIEIIC_00126 6.6e-237 YSH1 S Metallo-beta-lactamase superfamily
HCMIEIIC_00127 9.7e-17
HCMIEIIC_00128 8.7e-50
HCMIEIIC_00129 7.7e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HCMIEIIC_00130 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HCMIEIIC_00131 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HCMIEIIC_00132 3.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HCMIEIIC_00133 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCMIEIIC_00134 5.4e-138 est 3.1.1.1 S Serine aminopeptidase, S33
HCMIEIIC_00135 9.3e-31 secG U Preprotein translocase
HCMIEIIC_00136 1.7e-60
HCMIEIIC_00137 3.7e-293 clcA P chloride
HCMIEIIC_00138 1.2e-64
HCMIEIIC_00139 3.7e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCMIEIIC_00140 1.7e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCMIEIIC_00141 1.5e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HCMIEIIC_00142 2.2e-193 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCMIEIIC_00143 3.6e-188 cggR K Putative sugar-binding domain
HCMIEIIC_00145 2.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCMIEIIC_00146 1.6e-24 ohrR K helix_turn_helix multiple antibiotic resistance protein
HCMIEIIC_00147 1.7e-35 ohrR K helix_turn_helix multiple antibiotic resistance protein
HCMIEIIC_00148 1.6e-171 whiA K May be required for sporulation
HCMIEIIC_00149 6.5e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HCMIEIIC_00150 8.2e-165 rapZ S Displays ATPase and GTPase activities
HCMIEIIC_00151 2.4e-23
HCMIEIIC_00152 2.2e-205 yceI G Sugar (and other) transporter
HCMIEIIC_00153 3.2e-171 mdtG EGP Major facilitator Superfamily
HCMIEIIC_00154 7.7e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCMIEIIC_00155 3.8e-55 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCMIEIIC_00156 1.7e-154 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCMIEIIC_00157 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
HCMIEIIC_00158 3.6e-171 ccpB 5.1.1.1 K lacI family
HCMIEIIC_00159 8.2e-67
HCMIEIIC_00161 2.9e-218 tnpB L Putative transposase DNA-binding domain
HCMIEIIC_00162 4.6e-139 cad S FMN_bind
HCMIEIIC_00163 0.0 ndh 1.6.99.3 C NADH dehydrogenase
HCMIEIIC_00164 1.7e-81 ynhH S NusG domain II
HCMIEIIC_00165 5.2e-99 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HCMIEIIC_00166 4.5e-180 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCMIEIIC_00167 2.7e-80
HCMIEIIC_00168 5.8e-146 T Calcineurin-like phosphoesterase superfamily domain
HCMIEIIC_00169 4.6e-97
HCMIEIIC_00170 2.6e-158
HCMIEIIC_00171 2.7e-152 V ATPases associated with a variety of cellular activities
HCMIEIIC_00172 7.1e-215
HCMIEIIC_00173 3.4e-192
HCMIEIIC_00174 2.5e-121 1.5.1.40 S Rossmann-like domain
HCMIEIIC_00175 6.1e-191 XK27_00915 C Luciferase-like monooxygenase
HCMIEIIC_00176 1.2e-97 yacP S YacP-like NYN domain
HCMIEIIC_00177 7e-144 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCMIEIIC_00178 2.1e-73 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCMIEIIC_00179 2.5e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCMIEIIC_00180 9.7e-245 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HCMIEIIC_00181 8.6e-99
HCMIEIIC_00183 3.3e-259 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCMIEIIC_00184 2.9e-140 yhfC S Putative membrane peptidase family (DUF2324)
HCMIEIIC_00185 8e-156 S Membrane
HCMIEIIC_00186 2.8e-61 K helix_turn_helix gluconate operon transcriptional repressor
HCMIEIIC_00187 2.9e-293 V ABC transporter transmembrane region
HCMIEIIC_00188 4.4e-223 inlJ M MucBP domain
HCMIEIIC_00189 1.9e-69 S ABC-2 family transporter protein
HCMIEIIC_00190 3.1e-95 V ABC transporter, ATP-binding protein
HCMIEIIC_00191 1.4e-108 K sequence-specific DNA binding
HCMIEIIC_00192 1.8e-201 yacL S domain protein
HCMIEIIC_00193 8.5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCMIEIIC_00194 1.9e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
HCMIEIIC_00195 4.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
HCMIEIIC_00196 1e-256 pepC 3.4.22.40 E aminopeptidase
HCMIEIIC_00197 3.8e-262 pepC 3.4.22.40 E Peptidase C1-like family
HCMIEIIC_00198 3.6e-194
HCMIEIIC_00199 1.9e-209 S ABC-2 family transporter protein
HCMIEIIC_00200 4.3e-166 V ATPases associated with a variety of cellular activities
HCMIEIIC_00201 0.0 kup P Transport of potassium into the cell
HCMIEIIC_00202 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
HCMIEIIC_00203 1.5e-92 ccpN K Domain in cystathionine beta-synthase and other proteins.
HCMIEIIC_00204 2.9e-122 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCMIEIIC_00205 4e-201 ltrA S Bacterial low temperature requirement A protein (LtrA)
HCMIEIIC_00206 7.2e-46
HCMIEIIC_00207 2.8e-194 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HCMIEIIC_00208 8.8e-09 yhjA S CsbD-like
HCMIEIIC_00209 3.1e-151 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HCMIEIIC_00210 9.2e-191 EGP Major facilitator Superfamily
HCMIEIIC_00211 8.5e-115 udp 2.4.2.3, 3.2.2.4 F Phosphorylase superfamily
HCMIEIIC_00212 7.3e-172 EGP Major facilitator Superfamily
HCMIEIIC_00213 3.1e-67 KT Purine catabolism regulatory protein-like family
HCMIEIIC_00214 5.4e-08
HCMIEIIC_00215 2.5e-32
HCMIEIIC_00216 1.1e-32
HCMIEIIC_00217 4.9e-224 pimH EGP Major facilitator Superfamily
HCMIEIIC_00218 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCMIEIIC_00219 3e-148 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCMIEIIC_00221 8.7e-93
HCMIEIIC_00223 4e-18 bacI V MacB-like periplasmic core domain
HCMIEIIC_00224 3.1e-55 macB V ABC transporter, ATP-binding protein
HCMIEIIC_00226 3.2e-128 3.4.22.70 M Sortase family
HCMIEIIC_00227 2.4e-289 M Cna protein B-type domain
HCMIEIIC_00228 5.1e-259 M domain protein
HCMIEIIC_00229 0.0 M domain protein
HCMIEIIC_00230 3.3e-103
HCMIEIIC_00231 4.3e-225 N Uncharacterized conserved protein (DUF2075)
HCMIEIIC_00232 1.8e-206 MA20_36090 S Protein of unknown function (DUF2974)
HCMIEIIC_00233 4.1e-97 K Helix-turn-helix XRE-family like proteins
HCMIEIIC_00234 1.4e-56 K Transcriptional regulator PadR-like family
HCMIEIIC_00235 7.1e-136
HCMIEIIC_00236 6.6e-134
HCMIEIIC_00237 9e-44 S Enterocin A Immunity
HCMIEIIC_00238 2.7e-186 tas C Aldo/keto reductase family
HCMIEIIC_00239 2.5e-253 yjjP S Putative threonine/serine exporter
HCMIEIIC_00240 7e-59
HCMIEIIC_00241 8.4e-225 mesE M Transport protein ComB
HCMIEIIC_00242 1e-279 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HCMIEIIC_00243 4.2e-77 usp5 T universal stress protein
HCMIEIIC_00244 4.7e-64 K Helix-turn-helix XRE-family like proteins
HCMIEIIC_00245 4.9e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
HCMIEIIC_00246 1.3e-223 queG 1.17.99.6 C Domain of unknown function (DUF1730)
HCMIEIIC_00247 4.1e-62
HCMIEIIC_00248 1e-85 bioY S BioY family
HCMIEIIC_00250 5.4e-102 Q methyltransferase
HCMIEIIC_00251 2.6e-98 T Sh3 type 3 domain protein
HCMIEIIC_00252 3.9e-113 yfeJ 6.3.5.2 F glutamine amidotransferase
HCMIEIIC_00253 8e-137 S Uncharacterized protein conserved in bacteria (DUF2263)
HCMIEIIC_00254 4.9e-257 yhdP S Transporter associated domain
HCMIEIIC_00255 7.2e-144 S Alpha beta hydrolase
HCMIEIIC_00256 1.6e-193 I Acyltransferase
HCMIEIIC_00257 3.1e-262 lmrB EGP Major facilitator Superfamily
HCMIEIIC_00258 8.8e-84 S Domain of unknown function (DUF4811)
HCMIEIIC_00259 4.2e-95 maf D nucleoside-triphosphate diphosphatase activity
HCMIEIIC_00260 9.3e-135 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCMIEIIC_00261 2.8e-219 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCMIEIIC_00262 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCMIEIIC_00263 0.0 ydaO E amino acid
HCMIEIIC_00264 1.1e-56 S Domain of unknown function (DUF1827)
HCMIEIIC_00265 1e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCMIEIIC_00266 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCMIEIIC_00267 3.6e-109 ydiL S CAAX protease self-immunity
HCMIEIIC_00268 3.7e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HCMIEIIC_00269 1.2e-183
HCMIEIIC_00270 2.8e-157 ytrB V ABC transporter
HCMIEIIC_00271 1e-60 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HCMIEIIC_00272 4.2e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCMIEIIC_00273 0.0 uup S ABC transporter, ATP-binding protein
HCMIEIIC_00274 1.6e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_00275 2.6e-186 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCMIEIIC_00276 2.3e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HCMIEIIC_00277 5.3e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HCMIEIIC_00278 7e-119
HCMIEIIC_00279 7.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HCMIEIIC_00280 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
HCMIEIIC_00281 1.3e-142 fat 3.1.2.21 I Acyl-ACP thioesterase
HCMIEIIC_00282 1.7e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCMIEIIC_00283 1.7e-57 yabA L Involved in initiation control of chromosome replication
HCMIEIIC_00284 1.3e-174 holB 2.7.7.7 L DNA polymerase III
HCMIEIIC_00285 7.8e-52 yaaQ S Cyclic-di-AMP receptor
HCMIEIIC_00286 2.2e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCMIEIIC_00287 8.7e-38 S Protein of unknown function (DUF2508)
HCMIEIIC_00288 5.6e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCMIEIIC_00289 1.5e-33 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCMIEIIC_00290 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCMIEIIC_00291 8.9e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCMIEIIC_00292 4.7e-49
HCMIEIIC_00293 3.4e-106 rsmC 2.1.1.172 J Methyltransferase
HCMIEIIC_00294 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCMIEIIC_00295 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCMIEIIC_00296 2.2e-65
HCMIEIIC_00297 4.1e-30 K Transcriptional
HCMIEIIC_00298 0.0 V ABC transporter
HCMIEIIC_00299 0.0 V ABC transporter
HCMIEIIC_00300 4.5e-166 2.7.13.3 T GHKL domain
HCMIEIIC_00301 3e-125 T LytTr DNA-binding domain
HCMIEIIC_00302 6.9e-172 yqhA G Aldose 1-epimerase
HCMIEIIC_00303 5.7e-166 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HCMIEIIC_00304 7.7e-80 manR 2.7.1.194, 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HCMIEIIC_00305 1.3e-145 tatD L hydrolase, TatD family
HCMIEIIC_00306 1.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCMIEIIC_00307 1.4e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCMIEIIC_00308 1.1e-37 veg S Biofilm formation stimulator VEG
HCMIEIIC_00309 5.8e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCMIEIIC_00310 6.7e-159 czcD P cation diffusion facilitator family transporter
HCMIEIIC_00311 1.3e-121 ybbM S Uncharacterised protein family (UPF0014)
HCMIEIIC_00312 6.5e-119 ybbL S ABC transporter, ATP-binding protein
HCMIEIIC_00313 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HCMIEIIC_00314 3.5e-219 ysaA V RDD family
HCMIEIIC_00315 1.4e-211 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCMIEIIC_00316 1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCMIEIIC_00317 8.6e-51 nudA S ASCH
HCMIEIIC_00318 1.6e-73
HCMIEIIC_00319 1.8e-60 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCMIEIIC_00320 3.8e-177 S DUF218 domain
HCMIEIIC_00321 2.4e-83 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
HCMIEIIC_00322 7.4e-266 ywfO S HD domain protein
HCMIEIIC_00323 6.7e-156 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HCMIEIIC_00324 3.5e-79 ywiB S Domain of unknown function (DUF1934)
HCMIEIIC_00325 2.9e-61 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCMIEIIC_00326 7.9e-152 S Protein of unknown function (DUF1211)
HCMIEIIC_00329 5.9e-219 ndh 1.6.99.3 C NADH dehydrogenase
HCMIEIIC_00330 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCMIEIIC_00332 9.1e-33
HCMIEIIC_00334 2e-214 tnpB L Putative transposase DNA-binding domain
HCMIEIIC_00335 2.5e-77 L Resolvase, N-terminal
HCMIEIIC_00336 5.2e-104 tag 3.2.2.20 L glycosylase
HCMIEIIC_00337 4.8e-205 yceJ EGP Major facilitator Superfamily
HCMIEIIC_00338 1.2e-48 K Helix-turn-helix domain
HCMIEIIC_00339 2e-28
HCMIEIIC_00340 6.5e-28 relB L RelB antitoxin
HCMIEIIC_00341 8.3e-252 L Exonuclease
HCMIEIIC_00342 6.3e-32
HCMIEIIC_00343 2.3e-13
HCMIEIIC_00345 5.9e-13
HCMIEIIC_00346 5.6e-20
HCMIEIIC_00347 1.2e-76 ohr O OsmC-like protein
HCMIEIIC_00348 2.3e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HCMIEIIC_00349 3.8e-102 dhaL 2.7.1.121 S Dak2
HCMIEIIC_00350 9.6e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
HCMIEIIC_00351 4e-104 K Bacterial regulatory proteins, tetR family
HCMIEIIC_00352 9.4e-17
HCMIEIIC_00353 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HCMIEIIC_00354 3.1e-173
HCMIEIIC_00355 4.6e-196 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HCMIEIIC_00356 1.9e-150 metQ_4 P Belongs to the nlpA lipoprotein family
HCMIEIIC_00359 6e-22
HCMIEIIC_00361 1.9e-136 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HCMIEIIC_00362 2.6e-308 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HCMIEIIC_00363 3.4e-60 2.7.1.191 G PTS system fructose IIA component
HCMIEIIC_00364 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HCMIEIIC_00365 1.3e-134 G PTS system mannose/fructose/sorbose family IID component
HCMIEIIC_00366 7.6e-125 G PTS system sorbose-specific iic component
HCMIEIIC_00367 3.3e-75 2.7.1.191 G PTS system sorbose subfamily IIB component
HCMIEIIC_00368 4.6e-164 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HCMIEIIC_00369 7.6e-45 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HCMIEIIC_00370 3.7e-151 S hydrolase
HCMIEIIC_00371 1.1e-261 npr 1.11.1.1 C NADH oxidase
HCMIEIIC_00372 3.7e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HCMIEIIC_00373 1.1e-184 hrtB V ABC transporter permease
HCMIEIIC_00374 9.6e-86 ygfC K Bacterial regulatory proteins, tetR family
HCMIEIIC_00375 4.8e-145 yqfZ 3.2.1.17 M hydrolase, family 25
HCMIEIIC_00376 1.3e-17 S YvrJ protein family
HCMIEIIC_00377 8.7e-08 K DNA-templated transcription, initiation
HCMIEIIC_00378 2.1e-77
HCMIEIIC_00379 6.7e-58 pnb C nitroreductase
HCMIEIIC_00380 2.4e-18 hxlR K Transcriptional regulator, HxlR family
HCMIEIIC_00381 9.6e-199 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_00382 5.8e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HCMIEIIC_00383 7e-87 4.3.3.7 E Dihydrodipicolinate synthetase family
HCMIEIIC_00384 4.3e-183 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HCMIEIIC_00385 3e-31 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_00386 9.9e-45 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_00387 9.6e-64 kdsD 5.3.1.13 M SIS domain
HCMIEIIC_00388 1.1e-218 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_00389 2.2e-189 malY 4.4.1.8 E Aminotransferase class I and II
HCMIEIIC_00390 5.8e-267 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_00391 7.2e-61 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_00392 1.2e-28 glvR K DNA-binding transcription factor activity
HCMIEIIC_00393 7.8e-175 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HCMIEIIC_00394 2.5e-85 celG 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
HCMIEIIC_00395 9.6e-188 2.7.1.199, 2.7.1.208 G pts system
HCMIEIIC_00396 1.9e-198 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HCMIEIIC_00397 2.4e-111 5.3.1.15 S Pfam:DUF1498
HCMIEIIC_00398 6.3e-126 G Domain of unknown function (DUF4432)
HCMIEIIC_00399 1.2e-162 G Phosphotransferase System
HCMIEIIC_00400 5.7e-44 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_00401 8e-66 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_00402 1.9e-167 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HCMIEIIC_00403 3.1e-30 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HCMIEIIC_00404 1.1e-230 manR K PRD domain
HCMIEIIC_00405 2e-232 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCMIEIIC_00406 1.2e-234 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HCMIEIIC_00407 7.5e-91 K antiterminator
HCMIEIIC_00408 9.4e-52 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HCMIEIIC_00409 3e-44 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCMIEIIC_00410 2.8e-20 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HCMIEIIC_00412 1.3e-36 glvR K Helix-turn-helix domain, rpiR family
HCMIEIIC_00413 1.6e-210 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HCMIEIIC_00414 6.6e-219 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HCMIEIIC_00415 9.3e-67 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HCMIEIIC_00416 2.2e-132 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
HCMIEIIC_00417 1.9e-25 2.7.1.194 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HCMIEIIC_00418 4e-168 S PTS system sugar-specific permease component
HCMIEIIC_00419 3.3e-37 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_00420 1.1e-57 gntR K rpiR family
HCMIEIIC_00421 1.3e-54 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HCMIEIIC_00422 5.9e-63 K DeoR C terminal sensor domain
HCMIEIIC_00423 4.1e-30 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_00424 8.1e-09 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_00425 4.8e-188 pts36C G iic component
HCMIEIIC_00427 2.9e-97 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
HCMIEIIC_00428 3.7e-250 frdC 1.3.5.4 C HI0933-like protein
HCMIEIIC_00429 3e-235 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HCMIEIIC_00430 2.7e-47 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HCMIEIIC_00431 4.7e-244 G Major Facilitator
HCMIEIIC_00432 1e-150 K Transcriptional regulator, LacI family
HCMIEIIC_00433 1.8e-145 cbiQ P cobalt transport
HCMIEIIC_00434 0.0 3.6.3.24 P ATP-binding cassette cobalt transporter
HCMIEIIC_00435 2.7e-97 S UPF0397 protein
HCMIEIIC_00436 1.1e-158 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
HCMIEIIC_00437 4.9e-109 K Transcriptional regulator, LysR family
HCMIEIIC_00438 3.2e-15 C FAD dependent oxidoreductase
HCMIEIIC_00439 9.8e-124 C FAD dependent oxidoreductase
HCMIEIIC_00440 2.6e-23 P transporter
HCMIEIIC_00441 4.8e-147 P transporter
HCMIEIIC_00442 1.4e-148 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HCMIEIIC_00443 2.3e-148 sorM G system, mannose fructose sorbose family IID component
HCMIEIIC_00444 3.6e-130 sorA U PTS system sorbose-specific iic component
HCMIEIIC_00445 1.9e-78 sorB 2.7.1.191, 2.7.1.206 G PTS system sorbose subfamily IIB component
HCMIEIIC_00446 3.6e-62 sorF 2.7.1.191, 2.7.1.206 G PTS system fructose IIA component
HCMIEIIC_00447 4.1e-131 IQ NAD dependent epimerase/dehydratase family
HCMIEIIC_00448 2.4e-162 sorC K sugar-binding domain protein
HCMIEIIC_00449 5.4e-239 sorE E Alcohol dehydrogenase GroES-like domain
HCMIEIIC_00450 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphotransferase system
HCMIEIIC_00451 6.4e-154 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HCMIEIIC_00452 3e-286 K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_00453 2e-156 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
HCMIEIIC_00454 2.5e-125 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HCMIEIIC_00455 1.4e-91 IQ KR domain
HCMIEIIC_00456 1.1e-180 2.7.1.53 G Belongs to the FGGY kinase family
HCMIEIIC_00457 9.9e-39 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HCMIEIIC_00458 1.1e-88 4.1.2.13 G DeoC/LacD family aldolase
HCMIEIIC_00459 6.3e-118 K helix_turn_helix gluconate operon transcriptional repressor
HCMIEIIC_00460 1.4e-44 K Acetyltransferase (GNAT) family
HCMIEIIC_00461 1.3e-212 dcuD C Tripartite ATP-independent periplasmic transporter, DctM component
HCMIEIIC_00462 2.1e-155 rihB 3.2.2.1 F Nucleoside
HCMIEIIC_00463 1.9e-86 6.3.4.4 S Zeta toxin
HCMIEIIC_00464 1.2e-149 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HCMIEIIC_00465 3.9e-48
HCMIEIIC_00466 1.4e-205 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HCMIEIIC_00467 6e-46 ptxB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_00468 2.5e-164 GKT transcriptional antiterminator
HCMIEIIC_00469 1e-28
HCMIEIIC_00470 3.9e-104
HCMIEIIC_00471 2.3e-67 K helix_turn_helix multiple antibiotic resistance protein
HCMIEIIC_00472 1.3e-121 ydiC1 EGP Major facilitator Superfamily
HCMIEIIC_00473 1.3e-77 ydiC1 EGP Major facilitator Superfamily
HCMIEIIC_00474 1e-94
HCMIEIIC_00475 4.5e-62
HCMIEIIC_00476 2.7e-69
HCMIEIIC_00477 7.1e-86 V AAA domain, putative AbiEii toxin, Type IV TA system
HCMIEIIC_00478 5.5e-52
HCMIEIIC_00479 0.0 pbpC M NTF2-like N-terminal transpeptidase domain
HCMIEIIC_00480 4.8e-143 S Protein of unknown function (DUF2785)
HCMIEIIC_00485 2.5e-36
HCMIEIIC_00486 1.8e-42 K DNA-binding helix-turn-helix protein
HCMIEIIC_00487 6.2e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCMIEIIC_00488 4.3e-159 rbsB G Periplasmic binding protein domain
HCMIEIIC_00489 5.2e-152 rbsC U Belongs to the binding-protein-dependent transport system permease family
HCMIEIIC_00490 1.3e-269 rbsA 3.6.3.17 G ABC transporter
HCMIEIIC_00491 8.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HCMIEIIC_00492 9.7e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HCMIEIIC_00493 2.1e-271 E Amino acid permease
HCMIEIIC_00494 9.4e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HCMIEIIC_00495 1.6e-101 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HCMIEIIC_00496 4.1e-150 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCMIEIIC_00497 1.1e-81 thiW S Thiamine-precursor transporter protein (ThiW)
HCMIEIIC_00498 1.7e-125 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HCMIEIIC_00499 1.9e-110 P cobalt transport
HCMIEIIC_00500 1.1e-242 P ABC transporter
HCMIEIIC_00501 5.7e-95 S ABC-type cobalt transport system, permease component
HCMIEIIC_00502 1.1e-27
HCMIEIIC_00503 2.4e-155
HCMIEIIC_00504 4.9e-88 V ATPases associated with a variety of cellular activities
HCMIEIIC_00505 1.3e-162 oppF P Oligopeptide/dipeptide transporter, C-terminal region
HCMIEIIC_00506 8.3e-196 oppD P Oligopeptide/dipeptide transporter, C-terminal region
HCMIEIIC_00507 2.4e-47
HCMIEIIC_00508 3e-173 amiD P N-terminal TM domain of oligopeptide transport permease C
HCMIEIIC_00509 1e-168 oppB P Binding-protein-dependent transport system inner membrane component
HCMIEIIC_00510 2.1e-299 E Bacterial extracellular solute-binding proteins, family 5 Middle
HCMIEIIC_00511 2.4e-35
HCMIEIIC_00512 6.4e-288 V ABC transporter transmembrane region
HCMIEIIC_00513 5.6e-281 V ABC transporter transmembrane region
HCMIEIIC_00514 9.3e-68 S Iron-sulphur cluster biosynthesis
HCMIEIIC_00515 9.9e-136 2.7.1.39 S Phosphotransferase enzyme family
HCMIEIIC_00516 1.5e-114 zmp3 O Zinc-dependent metalloprotease
HCMIEIIC_00517 2.7e-23 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HCMIEIIC_00519 1e-66 lytN 3.5.1.104 M LysM domain
HCMIEIIC_00520 0.0 lytN 3.5.1.104 M LysM domain
HCMIEIIC_00522 8e-49 lciIC K Helix-turn-helix XRE-family like proteins
HCMIEIIC_00523 5.9e-94 L restriction endonuclease
HCMIEIIC_00524 5.8e-37 L Plasmid pRiA4b ORF-3-like protein
HCMIEIIC_00526 1.3e-24 K Cro/C1-type HTH DNA-binding domain
HCMIEIIC_00531 1.6e-13 M LysM domain
HCMIEIIC_00532 4.6e-56
HCMIEIIC_00533 5.6e-79 K Putative DNA-binding domain
HCMIEIIC_00535 9.7e-44 S Abortive infection C-terminus
HCMIEIIC_00536 1.9e-159 L Belongs to the 'phage' integrase family
HCMIEIIC_00537 9.3e-11 S Domain of unknown function (DUF3173)
HCMIEIIC_00538 4.8e-81 K Replication initiation factor
HCMIEIIC_00539 6.5e-58 3.6.4.12 L Viral (Superfamily 1) RNA helicase
HCMIEIIC_00540 6.7e-112 L AAA domain
HCMIEIIC_00541 1.2e-145 pstS P T5orf172
HCMIEIIC_00542 3.3e-291 yeeB L DEAD-like helicases superfamily
HCMIEIIC_00543 9.1e-78 yeeA V Type II restriction enzyme, methylase subunits
HCMIEIIC_00544 6.2e-241 yeeA V Type II restriction enzyme, methylase subunits
HCMIEIIC_00545 2.1e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HCMIEIIC_00546 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HCMIEIIC_00547 4.4e-53
HCMIEIIC_00548 3.5e-40
HCMIEIIC_00549 5e-273 pipD E Dipeptidase
HCMIEIIC_00550 1.2e-82 ykhA 3.1.2.20 I Thioesterase superfamily
HCMIEIIC_00551 0.0 helD 3.6.4.12 L DNA helicase
HCMIEIIC_00552 2.3e-30 yxeA V FtsX-like permease family
HCMIEIIC_00553 1.3e-81 F NUDIX domain
HCMIEIIC_00554 2.5e-89 S AAA domain
HCMIEIIC_00555 2.3e-113 ycaC Q Isochorismatase family
HCMIEIIC_00556 2e-253 ydiC1 EGP Major Facilitator Superfamily
HCMIEIIC_00557 1.9e-212 yeaN P Transporter, major facilitator family protein
HCMIEIIC_00558 5e-173 iolS C Aldo keto reductase
HCMIEIIC_00559 4.4e-64 manO S Domain of unknown function (DUF956)
HCMIEIIC_00560 5.6e-169 manN G system, mannose fructose sorbose family IID component
HCMIEIIC_00561 1.6e-122 manY G PTS system
HCMIEIIC_00562 1.3e-182 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HCMIEIIC_00563 1.8e-218 EGP Major facilitator Superfamily
HCMIEIIC_00564 1e-187 K Helix-turn-helix XRE-family like proteins
HCMIEIIC_00565 2.3e-148 K Helix-turn-helix XRE-family like proteins
HCMIEIIC_00566 9.6e-158 K sequence-specific DNA binding
HCMIEIIC_00571 4.7e-307 ybfG M peptidoglycan-binding domain-containing protein
HCMIEIIC_00572 6.8e-36 ybfG M peptidoglycan-binding domain-containing protein
HCMIEIIC_00574 4e-287 glnP P ABC transporter permease
HCMIEIIC_00575 2e-39 glnQ E ABC transporter, ATP-binding protein
HCMIEIIC_00576 9.7e-77 glnQ E ABC transporter, ATP-binding protein
HCMIEIIC_00577 1.7e-39
HCMIEIIC_00578 2.3e-205 malE G Bacterial extracellular solute-binding protein
HCMIEIIC_00579 1.2e-129 S Protein of unknown function (DUF975)
HCMIEIIC_00580 6.8e-08 yqkB S Iron-sulphur cluster biosynthesis
HCMIEIIC_00581 1.2e-52
HCMIEIIC_00582 1.9e-80 S Bacterial PH domain
HCMIEIIC_00583 3.9e-284 ydbT S Bacterial PH domain
HCMIEIIC_00584 3.8e-142 S AAA ATPase domain
HCMIEIIC_00585 4.3e-166 yniA G Phosphotransferase enzyme family
HCMIEIIC_00586 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCMIEIIC_00587 6.1e-255 glnP P ABC transporter
HCMIEIIC_00588 9.1e-262 glnP P ABC transporter
HCMIEIIC_00589 8.3e-99 ydaF J Acetyltransferase (GNAT) domain
HCMIEIIC_00590 2.8e-103 S Stage II sporulation protein M
HCMIEIIC_00591 1.9e-167 yeaC S ATPase family associated with various cellular activities (AAA)
HCMIEIIC_00592 7.1e-133 yeaD S Protein of unknown function DUF58
HCMIEIIC_00593 0.0 yebA E Transglutaminase/protease-like homologues
HCMIEIIC_00594 7e-214 lsgC M Glycosyl transferases group 1
HCMIEIIC_00595 4.6e-255 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HCMIEIIC_00596 2.6e-191 L Transposase and inactivated derivatives, IS30 family
HCMIEIIC_00597 2.8e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCMIEIIC_00598 3.3e-42 rpmE2 J Ribosomal protein L31
HCMIEIIC_00599 1.4e-72
HCMIEIIC_00600 5e-122
HCMIEIIC_00601 1.9e-123 S Tetratricopeptide repeat
HCMIEIIC_00602 3.3e-146
HCMIEIIC_00603 6.2e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCMIEIIC_00604 4.5e-264 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCMIEIIC_00605 1.7e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCMIEIIC_00606 1.6e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCMIEIIC_00607 2.4e-37
HCMIEIIC_00608 5.6e-62 ndoA L Toxic component of a toxin-antitoxin (TA) module
HCMIEIIC_00609 1.4e-12
HCMIEIIC_00610 1.2e-86 S QueT transporter
HCMIEIIC_00611 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
HCMIEIIC_00612 4e-278 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HCMIEIIC_00613 1.8e-130 yciB M ErfK YbiS YcfS YnhG
HCMIEIIC_00614 5.1e-119 S (CBS) domain
HCMIEIIC_00615 3.4e-114 1.6.5.2 S Flavodoxin-like fold
HCMIEIIC_00616 9.1e-238 XK27_06930 S ABC-2 family transporter protein
HCMIEIIC_00617 2.9e-96 padR K Transcriptional regulator PadR-like family
HCMIEIIC_00618 5e-262 S Putative peptidoglycan binding domain
HCMIEIIC_00619 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HCMIEIIC_00620 2.1e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCMIEIIC_00621 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCMIEIIC_00622 1.6e-280 yabM S Polysaccharide biosynthesis protein
HCMIEIIC_00623 1.8e-38 yabO J S4 domain protein
HCMIEIIC_00624 4.4e-65 divIC D cell cycle
HCMIEIIC_00625 5.2e-81 yabR J RNA binding
HCMIEIIC_00626 2.1e-241 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCMIEIIC_00627 5.9e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HCMIEIIC_00628 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCMIEIIC_00629 1.9e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCMIEIIC_00630 2.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCMIEIIC_00631 5.6e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HCMIEIIC_00632 1.8e-101 V Restriction endonuclease
HCMIEIIC_00633 6.3e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HCMIEIIC_00634 2e-46
HCMIEIIC_00635 6.5e-210 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HCMIEIIC_00636 1.5e-209 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
HCMIEIIC_00637 1.3e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HCMIEIIC_00639 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCMIEIIC_00640 3.7e-79 F Nucleoside 2-deoxyribosyltransferase
HCMIEIIC_00641 4e-251 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCMIEIIC_00642 6e-64
HCMIEIIC_00643 2.6e-291 frvR K Mga helix-turn-helix domain
HCMIEIIC_00644 6.5e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
HCMIEIIC_00645 4e-104 ygaC J Belongs to the UPF0374 family
HCMIEIIC_00646 2.8e-96
HCMIEIIC_00647 9.5e-74 S Acetyltransferase (GNAT) domain
HCMIEIIC_00648 6.8e-207 yueF S AI-2E family transporter
HCMIEIIC_00649 5.1e-243 hlyX S Transporter associated domain
HCMIEIIC_00650 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HCMIEIIC_00651 4.3e-46 XK27_09445 S Domain of unknown function (DUF1827)
HCMIEIIC_00652 0.0 clpE O Belongs to the ClpA ClpB family
HCMIEIIC_00653 2e-28
HCMIEIIC_00654 2.7e-39 ptsH G phosphocarrier protein HPR
HCMIEIIC_00655 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCMIEIIC_00656 7.4e-12
HCMIEIIC_00657 1.2e-253 iolT EGP Major facilitator Superfamily
HCMIEIIC_00659 1e-102 thiT S Thiamine transporter protein (Thia_YuaJ)
HCMIEIIC_00660 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCMIEIIC_00661 1.6e-210 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCMIEIIC_00662 2.3e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HCMIEIIC_00663 6.4e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCMIEIIC_00664 3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCMIEIIC_00665 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCMIEIIC_00666 4e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCMIEIIC_00667 2.1e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HCMIEIIC_00668 2.9e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCMIEIIC_00669 2.9e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HCMIEIIC_00670 3.6e-219 purD 6.3.4.13 F Belongs to the GARS family
HCMIEIIC_00671 2.4e-85 epsB M biosynthesis protein
HCMIEIIC_00672 2.8e-131 E lipolytic protein G-D-S-L family
HCMIEIIC_00673 1.1e-81 ccl S QueT transporter
HCMIEIIC_00674 1.5e-124 IQ Enoyl-(Acyl carrier protein) reductase
HCMIEIIC_00675 1.4e-36 XK27_01315 S Protein of unknown function (DUF2829)
HCMIEIIC_00676 5e-48 K Cro/C1-type HTH DNA-binding domain
HCMIEIIC_00677 3.3e-115 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
HCMIEIIC_00678 1.5e-180 oppF P Belongs to the ABC transporter superfamily
HCMIEIIC_00679 6.3e-196 oppD P Belongs to the ABC transporter superfamily
HCMIEIIC_00680 1.4e-176 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCMIEIIC_00681 3e-162 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCMIEIIC_00682 7.4e-305 oppA E ABC transporter, substratebinding protein
HCMIEIIC_00683 1.8e-254 EGP Major facilitator Superfamily
HCMIEIIC_00684 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCMIEIIC_00685 6.4e-128 yrjD S LUD domain
HCMIEIIC_00686 6.8e-289 lutB C 4Fe-4S dicluster domain
HCMIEIIC_00687 4.7e-148 lutA C Cysteine-rich domain
HCMIEIIC_00688 9.1e-101
HCMIEIIC_00689 2.8e-52 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HCMIEIIC_00690 5.5e-211 S Bacterial protein of unknown function (DUF871)
HCMIEIIC_00691 1.8e-69 S Domain of unknown function (DUF3284)
HCMIEIIC_00692 4e-270 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCMIEIIC_00693 0.0 rafA 3.2.1.22 G alpha-galactosidase
HCMIEIIC_00694 1.4e-133 S Belongs to the UPF0246 family
HCMIEIIC_00695 9.1e-133 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
HCMIEIIC_00696 1.4e-84 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
HCMIEIIC_00697 0.0 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
HCMIEIIC_00698 1.3e-108
HCMIEIIC_00699 4.7e-98 S WxL domain surface cell wall-binding
HCMIEIIC_00700 1e-145 frlD 2.7.1.218 G pfkB family carbohydrate kinase
HCMIEIIC_00701 1.7e-107 speG J Acetyltransferase (GNAT) domain
HCMIEIIC_00702 4.9e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HCMIEIIC_00703 3e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_00704 6.9e-130 K UbiC transcription regulator-associated domain protein
HCMIEIIC_00705 3.8e-238 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCMIEIIC_00706 1.2e-73 S Domain of unknown function (DUF3284)
HCMIEIIC_00707 7e-214 S Bacterial protein of unknown function (DUF871)
HCMIEIIC_00708 8.5e-265 argH 4.3.2.1 E argininosuccinate lyase
HCMIEIIC_00709 8.8e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCMIEIIC_00710 9.3e-259 arpJ P ABC transporter permease
HCMIEIIC_00711 2.7e-123 S Alpha/beta hydrolase family
HCMIEIIC_00712 2e-129 K response regulator
HCMIEIIC_00713 0.0 vicK 2.7.13.3 T Histidine kinase
HCMIEIIC_00714 2.6e-258 yycH S YycH protein
HCMIEIIC_00715 4.4e-141 yycI S YycH protein
HCMIEIIC_00716 2.7e-154 vicX 3.1.26.11 S domain protein
HCMIEIIC_00717 8.5e-206 htrA 3.4.21.107 O serine protease
HCMIEIIC_00718 5.9e-70 S Iron-sulphur cluster biosynthesis
HCMIEIIC_00719 2.7e-76 hsp3 O Hsp20/alpha crystallin family
HCMIEIIC_00720 0.0 cadA P P-type ATPase
HCMIEIIC_00721 0.0 S Glycosyl hydrolase family 115
HCMIEIIC_00722 3.9e-282 G MFS/sugar transport protein
HCMIEIIC_00723 0.0 K helix_turn_helix, arabinose operon control protein
HCMIEIIC_00724 1.3e-133
HCMIEIIC_00725 2.5e-297 E ABC transporter, substratebinding protein
HCMIEIIC_00726 7.3e-250 E Peptidase dimerisation domain
HCMIEIIC_00727 6.8e-100
HCMIEIIC_00728 4.1e-198 ybiR P Citrate transporter
HCMIEIIC_00729 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCMIEIIC_00730 9.8e-66 6.3.3.2 S ASCH
HCMIEIIC_00731 1.3e-122
HCMIEIIC_00732 2.3e-84 K Acetyltransferase (GNAT) domain
HCMIEIIC_00733 2.7e-132 wzb 3.1.3.48 T Tyrosine phosphatase family
HCMIEIIC_00734 1.7e-77 hisB 2.7.7.71, 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19, 5.3.1.28, 6.3.2.10 GT9 E HAD-hyrolase-like
HCMIEIIC_00735 6.6e-79 MA20_25245 K FR47-like protein
HCMIEIIC_00736 6.5e-108 S alpha beta
HCMIEIIC_00737 5.9e-36
HCMIEIIC_00738 2.8e-57
HCMIEIIC_00739 1.2e-145 V ABC transporter transmembrane region
HCMIEIIC_00741 2.7e-49 sugE U Multidrug resistance protein
HCMIEIIC_00742 3.7e-142 Q Methyltransferase
HCMIEIIC_00743 2.5e-74 adhR K helix_turn_helix, mercury resistance
HCMIEIIC_00744 2.5e-158 1.1.1.346 S reductase
HCMIEIIC_00745 1.5e-172 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HCMIEIIC_00746 2.7e-202 S endonuclease exonuclease phosphatase family protein
HCMIEIIC_00748 1.8e-129 G PTS system sorbose-specific iic component
HCMIEIIC_00749 9.2e-150 G PTS system mannose/fructose/sorbose family IID component
HCMIEIIC_00750 7.6e-80 2.7.1.191 G PTS system sorbose subfamily IIB component
HCMIEIIC_00751 6.9e-162 ybbH_2 K Helix-turn-helix domain, rpiR family
HCMIEIIC_00752 2.9e-146 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HCMIEIIC_00753 2.5e-189 blaA6 V Beta-lactamase
HCMIEIIC_00754 1.5e-146 3.5.2.6 V Beta-lactamase enzyme family
HCMIEIIC_00755 5.1e-224 EGP Major facilitator Superfamily
HCMIEIIC_00756 8.1e-210 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HCMIEIIC_00757 4.7e-163 ugpA P ABC-type sugar transport systems, permease components
HCMIEIIC_00758 2.2e-148 ugpE G ABC transporter permease
HCMIEIIC_00759 6.4e-241 ugpB G Bacterial extracellular solute-binding protein
HCMIEIIC_00760 3.3e-68 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCMIEIIC_00761 3.6e-131 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCMIEIIC_00762 1.8e-262 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCMIEIIC_00763 9.9e-108 pncA Q Isochorismatase family
HCMIEIIC_00764 9.6e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
HCMIEIIC_00765 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
HCMIEIIC_00766 2.8e-97 K Helix-turn-helix domain
HCMIEIIC_00768 3.7e-111 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HCMIEIIC_00769 7.6e-91 yjgM K Acetyltransferase (GNAT) domain
HCMIEIIC_00770 4.7e-204 3.2.1.51 GH29 G Alpha-L-fucosidase
HCMIEIIC_00771 1.5e-214 uhpT EGP Major facilitator Superfamily
HCMIEIIC_00772 1.2e-129 ymfC K UTRA
HCMIEIIC_00773 4.1e-245 3.5.1.18 E Peptidase family M20/M25/M40
HCMIEIIC_00774 9.8e-180 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
HCMIEIIC_00775 1.6e-155 bglK_1 GK ROK family
HCMIEIIC_00776 3.8e-41
HCMIEIIC_00777 0.0 O Belongs to the peptidase S8 family
HCMIEIIC_00778 1.2e-213 ulaG S Beta-lactamase superfamily domain
HCMIEIIC_00779 3.6e-79 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_00780 1e-279 ulaA S PTS system sugar-specific permease component
HCMIEIIC_00781 1.4e-44 sgaB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_00782 1.6e-114 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HCMIEIIC_00783 4.9e-137 repA K DeoR C terminal sensor domain
HCMIEIIC_00784 5.4e-167 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HCMIEIIC_00785 5.3e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HCMIEIIC_00786 1.6e-137 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HCMIEIIC_00787 1.6e-28 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
HCMIEIIC_00788 2.5e-24 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HCMIEIIC_00789 2.7e-16 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HCMIEIIC_00790 2e-17
HCMIEIIC_00791 5.3e-279 mntH P H( )-stimulated, divalent metal cation uptake system
HCMIEIIC_00792 0.0 pacL P P-type ATPase
HCMIEIIC_00793 9.8e-64
HCMIEIIC_00794 4.2e-226 EGP Major Facilitator Superfamily
HCMIEIIC_00795 2.1e-311 mco Q Multicopper oxidase
HCMIEIIC_00796 1e-24
HCMIEIIC_00797 1.7e-111 2.5.1.105 P Cation efflux family
HCMIEIIC_00798 8.7e-51 czrA K Transcriptional regulator, ArsR family
HCMIEIIC_00799 5.4e-175 sitA P Belongs to the bacterial solute-binding protein 9 family
HCMIEIIC_00800 9.5e-145 mtsB U ABC 3 transport family
HCMIEIIC_00801 1.9e-130 mntB 3.6.3.35 P ABC transporter
HCMIEIIC_00802 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCMIEIIC_00803 7.7e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
HCMIEIIC_00804 1.4e-118 GM NmrA-like family
HCMIEIIC_00805 4.9e-85
HCMIEIIC_00806 8.6e-162 znuA P Belongs to the bacterial solute-binding protein 9 family
HCMIEIIC_00807 1.8e-19
HCMIEIIC_00809 3.4e-53 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCMIEIIC_00810 1.2e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCMIEIIC_00811 1.4e-286 G MFS/sugar transport protein
HCMIEIIC_00812 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase concanavalin-like domain
HCMIEIIC_00813 1.6e-169 ssuA P NMT1-like family
HCMIEIIC_00814 1.4e-292 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
HCMIEIIC_00815 3.4e-233 yfiQ I Acyltransferase family
HCMIEIIC_00816 1.3e-120 ssuB P ATPases associated with a variety of cellular activities
HCMIEIIC_00817 3.9e-145 ssuC U Binding-protein-dependent transport system inner membrane component
HCMIEIIC_00818 1.9e-121 S B3/4 domain
HCMIEIIC_00820 3.3e-29 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HCMIEIIC_00821 8.6e-15
HCMIEIIC_00822 0.0 V ABC transporter
HCMIEIIC_00823 0.0 V ATPases associated with a variety of cellular activities
HCMIEIIC_00824 1.4e-207 EGP Transmembrane secretion effector
HCMIEIIC_00825 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HCMIEIIC_00826 7e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCMIEIIC_00827 4.8e-103 K Bacterial regulatory proteins, tetR family
HCMIEIIC_00828 9.4e-184 yxeA V FtsX-like permease family
HCMIEIIC_00829 5.1e-125 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
HCMIEIIC_00830 6.4e-34
HCMIEIIC_00831 2e-135 tipA K TipAS antibiotic-recognition domain
HCMIEIIC_00832 1.5e-112 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCMIEIIC_00833 8e-122 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCMIEIIC_00834 3.2e-158 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCMIEIIC_00835 1.8e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCMIEIIC_00836 7.6e-115
HCMIEIIC_00837 3.1e-60 rplQ J Ribosomal protein L17
HCMIEIIC_00838 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCMIEIIC_00839 4.6e-59 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCMIEIIC_00840 2.1e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCMIEIIC_00841 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HCMIEIIC_00842 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCMIEIIC_00843 1.4e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCMIEIIC_00844 9.8e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCMIEIIC_00845 2.2e-62 rplO J Binds to the 23S rRNA
HCMIEIIC_00846 1.7e-24 rpmD J Ribosomal protein L30
HCMIEIIC_00847 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCMIEIIC_00848 4.6e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCMIEIIC_00849 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCMIEIIC_00850 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCMIEIIC_00851 1.1e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCMIEIIC_00852 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCMIEIIC_00853 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCMIEIIC_00854 1.4e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCMIEIIC_00855 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HCMIEIIC_00856 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCMIEIIC_00857 3.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCMIEIIC_00858 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCMIEIIC_00859 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCMIEIIC_00860 6.4e-106 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCMIEIIC_00861 2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCMIEIIC_00862 5.9e-109 rplD J Forms part of the polypeptide exit tunnel
HCMIEIIC_00863 3e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCMIEIIC_00864 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HCMIEIIC_00865 1.2e-68 psiE S Phosphate-starvation-inducible E
HCMIEIIC_00866 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HCMIEIIC_00867 5.5e-197 yfjR K WYL domain
HCMIEIIC_00868 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCMIEIIC_00869 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCMIEIIC_00870 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCMIEIIC_00871 0.0 M domain protein
HCMIEIIC_00872 0.0 M domain protein
HCMIEIIC_00873 6.1e-38 M domain protein
HCMIEIIC_00874 2.6e-83 3.4.23.43
HCMIEIIC_00875 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCMIEIIC_00876 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCMIEIIC_00877 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCMIEIIC_00878 3.6e-79 ctsR K Belongs to the CtsR family
HCMIEIIC_00887 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HCMIEIIC_00888 3.3e-133 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCMIEIIC_00889 1.1e-180 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCMIEIIC_00890 6.1e-45
HCMIEIIC_00891 3.1e-152 V Beta-lactamase
HCMIEIIC_00892 7.3e-192 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HCMIEIIC_00893 6e-137 H Protein of unknown function (DUF1698)
HCMIEIIC_00894 1.7e-140 puuD S peptidase C26
HCMIEIIC_00895 1.3e-53 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HCMIEIIC_00896 7.1e-30 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HCMIEIIC_00897 1.3e-78 K Psort location Cytoplasmic, score
HCMIEIIC_00898 2.1e-257 6.3.1.2 E Glutamine synthetase N-terminal domain
HCMIEIIC_00899 3e-220 S Amidohydrolase
HCMIEIIC_00900 8e-227 E Amino acid permease
HCMIEIIC_00901 2.5e-74 K helix_turn_helix, mercury resistance
HCMIEIIC_00902 3.2e-161 morA2 S reductase
HCMIEIIC_00903 1.1e-192 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HCMIEIIC_00904 4e-59 hxlR K Transcriptional regulator, HxlR family
HCMIEIIC_00905 1.5e-127 S membrane transporter protein
HCMIEIIC_00906 3.6e-197
HCMIEIIC_00907 4.6e-129 XK27_12140 V ATPases associated with a variety of cellular activities
HCMIEIIC_00908 4.2e-292 S Psort location CytoplasmicMembrane, score
HCMIEIIC_00909 2e-126 K Transcriptional regulatory protein, C terminal
HCMIEIIC_00910 5.1e-196 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HCMIEIIC_00911 1.9e-161 V ATPases associated with a variety of cellular activities
HCMIEIIC_00912 7.9e-197
HCMIEIIC_00913 1.4e-105
HCMIEIIC_00914 0.0 pepN 3.4.11.2 E aminopeptidase
HCMIEIIC_00915 7.1e-275 ycaM E amino acid
HCMIEIIC_00916 5.4e-237 G MFS/sugar transport protein
HCMIEIIC_00917 6e-72 S Protein of unknown function (DUF1440)
HCMIEIIC_00918 2e-160 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HCMIEIIC_00919 1e-173 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HCMIEIIC_00921 6.5e-36
HCMIEIIC_00922 1.3e-94
HCMIEIIC_00924 9.7e-211 metC 4.4.1.8 E cystathionine
HCMIEIIC_00925 2.8e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HCMIEIIC_00926 2.2e-120 tcyB E ABC transporter
HCMIEIIC_00927 2.2e-117
HCMIEIIC_00928 2.1e-250 brnQ U Component of the transport system for branched-chain amino acids
HCMIEIIC_00929 4.1e-76 S WxL domain surface cell wall-binding
HCMIEIIC_00930 1e-174 S Cell surface protein
HCMIEIIC_00931 1.2e-42
HCMIEIIC_00932 3.1e-247 XK27_00720 S Leucine-rich repeat (LRR) protein
HCMIEIIC_00934 5e-120 S WxL domain surface cell wall-binding
HCMIEIIC_00935 4.5e-56
HCMIEIIC_00936 3e-114 N WxL domain surface cell wall-binding
HCMIEIIC_00937 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HCMIEIIC_00938 1.6e-166 yicL EG EamA-like transporter family
HCMIEIIC_00939 4.4e-300
HCMIEIIC_00940 8.5e-145 CcmA5 V ABC transporter
HCMIEIIC_00941 6.2e-78 S ECF-type riboflavin transporter, S component
HCMIEIIC_00942 6.7e-145 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HCMIEIIC_00943 5.2e-164 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
HCMIEIIC_00944 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HCMIEIIC_00945 0.0 XK27_09600 V ABC transporter, ATP-binding protein
HCMIEIIC_00946 0.0 V ABC transporter
HCMIEIIC_00947 4.7e-219 oxlT P Major Facilitator Superfamily
HCMIEIIC_00948 3.2e-127 treR K UTRA
HCMIEIIC_00949 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HCMIEIIC_00950 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCMIEIIC_00951 6.9e-213 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HCMIEIIC_00952 1.2e-269 yfnA E Amino Acid
HCMIEIIC_00953 4.3e-172 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HCMIEIIC_00954 4.8e-249 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCMIEIIC_00955 4.6e-31 K 'Cold-shock' DNA-binding domain
HCMIEIIC_00956 1.3e-70
HCMIEIIC_00957 5.1e-75 O OsmC-like protein
HCMIEIIC_00958 9.5e-283 lsa S ABC transporter
HCMIEIIC_00959 3.9e-113 ylbE GM NAD(P)H-binding
HCMIEIIC_00960 3.7e-160 yeaE S Aldo/keto reductase family
HCMIEIIC_00961 7.1e-256 yifK E Amino acid permease
HCMIEIIC_00962 2.8e-283 S Protein of unknown function (DUF3800)
HCMIEIIC_00963 0.0 yjcE P Sodium proton antiporter
HCMIEIIC_00964 3.2e-55 S Protein of unknown function (DUF3021)
HCMIEIIC_00965 2.8e-68 K LytTr DNA-binding domain
HCMIEIIC_00966 6.4e-146 cylB V ABC-2 type transporter
HCMIEIIC_00967 1.7e-157 cylA V ABC transporter
HCMIEIIC_00968 2.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
HCMIEIIC_00969 6.9e-113 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HCMIEIIC_00970 1.2e-52 ybjQ S Belongs to the UPF0145 family
HCMIEIIC_00971 1.1e-92 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
HCMIEIIC_00972 2e-158 3.5.1.10 C nadph quinone reductase
HCMIEIIC_00973 2.2e-243 amt P ammonium transporter
HCMIEIIC_00974 4.5e-177 yfeX P Peroxidase
HCMIEIIC_00975 1.5e-118 yhiD S MgtC family
HCMIEIIC_00976 9.3e-147 F DNA RNA non-specific endonuclease
HCMIEIIC_00978 1.1e-310 ybiT S ABC transporter, ATP-binding protein
HCMIEIIC_00979 2.2e-272 mutS L ATPase domain of DNA mismatch repair MUTS family
HCMIEIIC_00980 2.2e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
HCMIEIIC_00981 3.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCMIEIIC_00982 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HCMIEIIC_00983 1.4e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCMIEIIC_00984 3.3e-135 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
HCMIEIIC_00985 6.5e-138 lacT K PRD domain
HCMIEIIC_00986 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HCMIEIIC_00987 6.2e-247 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HCMIEIIC_00988 1.9e-50 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HCMIEIIC_00990 6.2e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCMIEIIC_00991 2.1e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HCMIEIIC_00992 6.5e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HCMIEIIC_00993 9.5e-162 K Transcriptional regulator
HCMIEIIC_00994 1.4e-192 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HCMIEIIC_00996 3.3e-70 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_00997 1.7e-48 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_00998 7.4e-256 gatC G PTS system sugar-specific permease component
HCMIEIIC_01000 1.7e-28
HCMIEIIC_01001 8e-188 V Beta-lactamase
HCMIEIIC_01002 1.3e-125 S Domain of unknown function (DUF4867)
HCMIEIIC_01003 2.1e-174 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HCMIEIIC_01004 5.6e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HCMIEIIC_01005 9.9e-94 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HCMIEIIC_01006 6.1e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
HCMIEIIC_01007 7.2e-141 lacR K DeoR C terminal sensor domain
HCMIEIIC_01008 3.6e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HCMIEIIC_01009 4.3e-211 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HCMIEIIC_01010 1.3e-51 sbcC L Putative exonuclease SbcCD, C subunit
HCMIEIIC_01011 1.6e-91 sbcC L Putative exonuclease SbcCD, C subunit
HCMIEIIC_01012 2.5e-259 sbcC L Putative exonuclease SbcCD, C subunit
HCMIEIIC_01013 1.3e-14
HCMIEIIC_01014 7.9e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HCMIEIIC_01015 9.6e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HCMIEIIC_01016 5.6e-147 gntR K rpiR family
HCMIEIIC_01017 1.9e-169 iolH G Xylose isomerase-like TIM barrel
HCMIEIIC_01018 1.7e-157 iolI 5.3.99.11 G Xylose isomerase-like TIM barrel
HCMIEIIC_01019 1.1e-65 iolK S Tautomerase enzyme
HCMIEIIC_01020 6.2e-157 iolJ 4.1.2.13, 4.1.2.29 G Fructose-bisphosphate aldolase class-II
HCMIEIIC_01021 1.2e-174 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HCMIEIIC_01022 5.3e-195 iolG2 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HCMIEIIC_01023 2.7e-191 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HCMIEIIC_01024 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HCMIEIIC_01025 5.4e-178 iolC 2.7.1.92 H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HCMIEIIC_01026 6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HCMIEIIC_01027 3.6e-274 iolA 1.2.1.18, 1.2.1.27 C Belongs to the aldehyde dehydrogenase family
HCMIEIIC_01028 1.9e-267 iolT EGP Major facilitator Superfamily
HCMIEIIC_01029 7.4e-141 iolR K DeoR C terminal sensor domain
HCMIEIIC_01030 1.1e-163 yvgN C Aldo keto reductase
HCMIEIIC_01031 2.7e-140 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HCMIEIIC_01032 8.7e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCMIEIIC_01033 3.6e-85 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCMIEIIC_01034 5.3e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HCMIEIIC_01035 1.2e-219 hpk31 2.7.13.3 T Histidine kinase
HCMIEIIC_01036 2.5e-121 K response regulator
HCMIEIIC_01037 1.7e-117
HCMIEIIC_01038 7.6e-272 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCMIEIIC_01039 2.8e-140 XK27_01040 S Protein of unknown function (DUF1129)
HCMIEIIC_01040 1.5e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCMIEIIC_01041 1.3e-30 yyzM S Bacterial protein of unknown function (DUF951)
HCMIEIIC_01042 2e-155 spo0J K Belongs to the ParB family
HCMIEIIC_01043 7.4e-138 soj D Sporulation initiation inhibitor
HCMIEIIC_01044 2.4e-142 noc K Belongs to the ParB family
HCMIEIIC_01045 2.8e-134 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HCMIEIIC_01046 3.7e-66
HCMIEIIC_01047 1e-127 cobQ S glutamine amidotransferase
HCMIEIIC_01049 5.7e-104 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HCMIEIIC_01050 8.5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HCMIEIIC_01051 5.2e-146 S Protein of unknown function (DUF979)
HCMIEIIC_01052 6e-115 S Protein of unknown function (DUF969)
HCMIEIIC_01053 1.2e-128 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HCMIEIIC_01054 5.1e-64 asp2 S Asp23 family, cell envelope-related function
HCMIEIIC_01055 5.1e-61 asp23 S Asp23 family, cell envelope-related function
HCMIEIIC_01056 2.5e-29
HCMIEIIC_01057 5.8e-89 S Protein conserved in bacteria
HCMIEIIC_01058 6.4e-38 S Transglycosylase associated protein
HCMIEIIC_01059 9.1e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
HCMIEIIC_01060 1.1e-170 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCMIEIIC_01061 6.7e-27
HCMIEIIC_01062 2.9e-35
HCMIEIIC_01063 2.7e-82 fld C Flavodoxin
HCMIEIIC_01064 2.1e-51
HCMIEIIC_01065 1.1e-64
HCMIEIIC_01067 1e-55 ywjH S Protein of unknown function (DUF1634)
HCMIEIIC_01068 4e-129 yxaA S Sulfite exporter TauE/SafE
HCMIEIIC_01069 5.1e-210 S TPM domain
HCMIEIIC_01070 1.7e-116
HCMIEIIC_01071 9.4e-261 nox 1.6.3.4 C NADH oxidase
HCMIEIIC_01072 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
HCMIEIIC_01073 3e-212 S nuclear-transcribed mRNA catabolic process, no-go decay
HCMIEIIC_01074 2.5e-80 S NUDIX domain
HCMIEIIC_01075 1.6e-74
HCMIEIIC_01076 2.5e-118 V ATPases associated with a variety of cellular activities
HCMIEIIC_01077 2e-116
HCMIEIIC_01078 7.3e-116
HCMIEIIC_01079 6.3e-76
HCMIEIIC_01080 1.8e-303 oppA E ABC transporter, substratebinding protein
HCMIEIIC_01081 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HCMIEIIC_01083 1.3e-16
HCMIEIIC_01084 6.6e-47 V ATPase activity
HCMIEIIC_01086 3e-89
HCMIEIIC_01089 5.8e-33
HCMIEIIC_01090 1.2e-101 nisT V ABC transporter
HCMIEIIC_01091 1.2e-139 nisT V ABC transporter
HCMIEIIC_01093 2.9e-119 S Acetyltransferase (GNAT) family
HCMIEIIC_01094 3e-290 E ABC transporter, substratebinding protein
HCMIEIIC_01095 3.6e-235 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HCMIEIIC_01096 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_01097 5.8e-194 ypdE E M42 glutamyl aminopeptidase
HCMIEIIC_01098 1.9e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HCMIEIIC_01099 1.8e-59 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_01100 2.7e-252 2.7.1.207 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCMIEIIC_01101 5.1e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HCMIEIIC_01102 6.8e-231 4.4.1.8 E Aminotransferase, class I
HCMIEIIC_01103 4.9e-219 S Uncharacterized protein conserved in bacteria (DUF2325)
HCMIEIIC_01104 2.2e-148 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HCMIEIIC_01105 8e-54 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HCMIEIIC_01106 1.5e-294 2.4.1.52 GT4 M Glycosyl transferases group 1
HCMIEIIC_01107 3.5e-64 XK27_08465 2.7.1.191 G PTS system fructose IIA component
HCMIEIIC_01108 1e-145 manZ_1 G PTS system mannose/fructose/sorbose family IID component
HCMIEIIC_01109 1.5e-140 XK27_08455 G PTS system sorbose-specific iic component
HCMIEIIC_01110 8.1e-82 manX_1 2.7.1.191 G PTS system sorbose subfamily IIB component
HCMIEIIC_01111 0.0 bgaC 3.2.1.23 G Glycosyl hydrolases family 35
HCMIEIIC_01112 4.1e-225 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCMIEIIC_01113 5.9e-219 agaS G SIS domain
HCMIEIIC_01114 3.4e-129 XK27_08435 K UTRA
HCMIEIIC_01115 3.7e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
HCMIEIIC_01116 5.7e-240 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HCMIEIIC_01117 3.1e-67 frvA 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_01118 2.6e-296 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_01119 1.7e-82
HCMIEIIC_01120 2.1e-238 malE G Bacterial extracellular solute-binding protein
HCMIEIIC_01121 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HCMIEIIC_01122 1.1e-116
HCMIEIIC_01123 4.8e-154 sepS16B
HCMIEIIC_01124 1.2e-234 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HCMIEIIC_01125 5.2e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HCMIEIIC_01126 7.8e-144 K CAT RNA binding domain
HCMIEIIC_01127 2e-258 lacE-1 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HCMIEIIC_01128 4.7e-260 nox 1.6.3.4 C NADH oxidase
HCMIEIIC_01129 2.1e-144 p75 M NlpC P60 family protein
HCMIEIIC_01130 2.2e-128 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HCMIEIIC_01131 4.4e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HCMIEIIC_01132 3.9e-116 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HCMIEIIC_01133 2.3e-232 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCMIEIIC_01134 1.4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HCMIEIIC_01135 1.2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HCMIEIIC_01136 1.8e-122 livF E ABC transporter
HCMIEIIC_01137 4.7e-140 livG E Branched-chain amino acid ATP-binding cassette transporter
HCMIEIIC_01138 2.1e-104 livM E Branched-chain amino acid transport system / permease component
HCMIEIIC_01139 4.4e-14 livM E Branched-chain amino acid transport system / permease component
HCMIEIIC_01140 6.7e-151 livH U Branched-chain amino acid transport system / permease component
HCMIEIIC_01141 1.3e-213 livJ E Receptor family ligand binding region
HCMIEIIC_01142 3.5e-74 S Threonine/Serine exporter, ThrE
HCMIEIIC_01143 1.3e-129 thrE S Putative threonine/serine exporter
HCMIEIIC_01144 2.9e-43 trxC O Belongs to the thioredoxin family
HCMIEIIC_01145 9e-71 S COG NOG38524 non supervised orthologous group
HCMIEIIC_01146 1.5e-135 nodJ V ABC-2 type transporter
HCMIEIIC_01147 3.2e-133 nodI V ABC transporter
HCMIEIIC_01148 6.8e-130 ydfF K Transcriptional
HCMIEIIC_01149 1.2e-109 S CAAX protease self-immunity
HCMIEIIC_01151 1.7e-277 V ABC transporter transmembrane region
HCMIEIIC_01152 6.7e-108 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCMIEIIC_01153 7.2e-71 K MarR family
HCMIEIIC_01154 0.0 uvrA3 L excinuclease ABC
HCMIEIIC_01155 1.4e-192 yghZ C Aldo keto reductase family protein
HCMIEIIC_01156 2.4e-142 S hydrolase
HCMIEIIC_01157 1.2e-58
HCMIEIIC_01158 4.8e-12
HCMIEIIC_01159 3.6e-115 yoaK S Protein of unknown function (DUF1275)
HCMIEIIC_01160 2.4e-127 yjhF G Phosphoglycerate mutase family
HCMIEIIC_01161 8.1e-151 yitU 3.1.3.104 S hydrolase
HCMIEIIC_01162 3.6e-90 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCMIEIIC_01163 6.5e-166 K LysR substrate binding domain
HCMIEIIC_01164 1.9e-225 EK Aminotransferase, class I
HCMIEIIC_01166 2.9e-45
HCMIEIIC_01167 9.4e-58
HCMIEIIC_01168 1.1e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCMIEIIC_01169 7.3e-116 ydfK S Protein of unknown function (DUF554)
HCMIEIIC_01170 2.2e-87
HCMIEIIC_01172 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_01173 1.3e-168 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HCMIEIIC_01174 1.5e-130 rpl K Helix-turn-helix domain, rpiR family
HCMIEIIC_01175 5.9e-126 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCMIEIIC_01176 1.1e-161 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCMIEIIC_01177 5.7e-288 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HCMIEIIC_01178 3.2e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HCMIEIIC_01179 5.6e-245 P Sodium:sulfate symporter transmembrane region
HCMIEIIC_01180 2.9e-157 K LysR substrate binding domain
HCMIEIIC_01181 1.3e-75
HCMIEIIC_01182 9e-72 K Transcriptional regulator
HCMIEIIC_01183 7.3e-245 ypiB EGP Major facilitator Superfamily
HCMIEIIC_01184 7.8e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HCMIEIIC_01186 4.3e-241 pts36C G PTS system sugar-specific permease component
HCMIEIIC_01187 1.1e-50 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_01188 3e-68 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_01189 1.2e-119 K DeoR C terminal sensor domain
HCMIEIIC_01191 4.4e-166 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HCMIEIIC_01192 9.1e-258 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HCMIEIIC_01193 3.8e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HCMIEIIC_01194 4.5e-285 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HCMIEIIC_01195 8.8e-227 iolF EGP Major facilitator Superfamily
HCMIEIIC_01196 4.1e-192 rhaR K helix_turn_helix, arabinose operon control protein
HCMIEIIC_01197 6.4e-215 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HCMIEIIC_01198 1.4e-65 S Protein of unknown function (DUF1093)
HCMIEIIC_01199 1.3e-120
HCMIEIIC_01200 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HCMIEIIC_01201 4.6e-305 plyA3 M Right handed beta helix region
HCMIEIIC_01202 2.9e-81
HCMIEIIC_01203 7.8e-269 M Heparinase II/III N-terminus
HCMIEIIC_01205 3.5e-66 G PTS system fructose IIA component
HCMIEIIC_01206 3.6e-143 agaD G PTS system mannose/fructose/sorbose family IID component
HCMIEIIC_01207 6.4e-132 G PTS system sorbose-specific iic component
HCMIEIIC_01208 3.5e-80 agaV 2.7.1.191 G PTS system sorbose subfamily IIB component
HCMIEIIC_01209 8.3e-205 ugl 3.2.1.180 GH88 S Glycosyl Hydrolase Family 88
HCMIEIIC_01210 8.4e-103 Z012_03480 S Psort location Cytoplasmic, score
HCMIEIIC_01211 1.9e-109 K Bacterial transcriptional regulator
HCMIEIIC_01212 1.7e-143 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HCMIEIIC_01213 3e-137 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCMIEIIC_01214 3.9e-87 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HCMIEIIC_01215 1.8e-152 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HCMIEIIC_01216 8.7e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCMIEIIC_01217 0.0 CP_0954 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
HCMIEIIC_01218 4.4e-198 rafA 3.2.1.22 G Melibiase
HCMIEIIC_01219 2.7e-15
HCMIEIIC_01221 4.2e-74 ssb_2 L Single-strand binding protein family
HCMIEIIC_01222 2.7e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HCMIEIIC_01223 4.9e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCMIEIIC_01224 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCMIEIIC_01225 1.5e-91 yhbO 3.5.1.124 S DJ-1/PfpI family
HCMIEIIC_01226 9.8e-280 cydA 1.10.3.14 C Cytochrome bd terminal oxidase subunit I
HCMIEIIC_01227 1e-182 cydB 1.10.3.14 C Cytochrome bd terminal oxidase subunit II
HCMIEIIC_01228 2.1e-28
HCMIEIIC_01229 9.2e-108 S CAAX protease self-immunity
HCMIEIIC_01230 5.5e-84 V Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
HCMIEIIC_01231 2.6e-266 L Transposase DDE domain
HCMIEIIC_01232 1.1e-161 V ABC transporter
HCMIEIIC_01233 4.5e-189 amtB P Ammonium Transporter Family
HCMIEIIC_01234 4.3e-211 P Pyridine nucleotide-disulphide oxidoreductase
HCMIEIIC_01235 4e-125 usp 3.5.1.28 CBM50 D CHAP domain
HCMIEIIC_01236 0.0 ylbB V ABC transporter permease
HCMIEIIC_01237 4.1e-127 macB V ABC transporter, ATP-binding protein
HCMIEIIC_01238 3e-96 K transcriptional regulator
HCMIEIIC_01239 6.6e-153 supH G Sucrose-6F-phosphate phosphohydrolase
HCMIEIIC_01240 1.4e-45
HCMIEIIC_01241 5.9e-127 S membrane transporter protein
HCMIEIIC_01242 2.1e-103 S Protein of unknown function (DUF1211)
HCMIEIIC_01243 5e-113 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HCMIEIIC_01244 8.5e-54
HCMIEIIC_01246 7.6e-285 pipD E Dipeptidase
HCMIEIIC_01247 6.1e-106 S Membrane
HCMIEIIC_01248 2.1e-86
HCMIEIIC_01249 5.9e-53
HCMIEIIC_01251 6.1e-244 ybfG M peptidoglycan-binding domain-containing protein
HCMIEIIC_01252 2.4e-122 azlC E branched-chain amino acid
HCMIEIIC_01253 1.5e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HCMIEIIC_01254 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HCMIEIIC_01255 0.0 M Glycosyl hydrolase family 59
HCMIEIIC_01256 1.4e-116 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HCMIEIIC_01257 4.6e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HCMIEIIC_01258 9.5e-280 uxaC 5.3.1.12 G glucuronate isomerase
HCMIEIIC_01259 3.3e-216 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HCMIEIIC_01260 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
HCMIEIIC_01261 7.8e-267 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HCMIEIIC_01262 1.8e-229 G Major Facilitator
HCMIEIIC_01263 1.2e-126 kdgR K FCD domain
HCMIEIIC_01264 4.3e-190 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HCMIEIIC_01265 0.0 M Glycosyl hydrolase family 59
HCMIEIIC_01266 1.6e-57
HCMIEIIC_01267 3.8e-64 S pyridoxamine 5-phosphate
HCMIEIIC_01268 8.3e-241 EGP Major facilitator Superfamily
HCMIEIIC_01269 2e-219 3.1.1.83 I Alpha beta hydrolase
HCMIEIIC_01270 8.4e-46 K Bacterial regulatory proteins, tetR family
HCMIEIIC_01273 6.3e-197 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HCMIEIIC_01274 9.4e-145 maeN C 2-hydroxycarboxylate transporter family
HCMIEIIC_01275 1.7e-70 maeN C 2-hydroxycarboxylate transporter family
HCMIEIIC_01276 1.8e-268 dcuS 2.7.13.3 T Single cache domain 3
HCMIEIIC_01277 4.1e-119 dpiA KT cheY-homologous receiver domain
HCMIEIIC_01278 5.5e-95
HCMIEIIC_01279 3.7e-118 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCMIEIIC_01281 1.8e-148 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
HCMIEIIC_01282 1.4e-68
HCMIEIIC_01283 6e-131 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
HCMIEIIC_01284 5.8e-169 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HCMIEIIC_01286 8.8e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCMIEIIC_01287 1.5e-180 D Alpha beta
HCMIEIIC_01288 5.9e-185 lipA I Carboxylesterase family
HCMIEIIC_01289 1.7e-215 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HCMIEIIC_01290 1e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCMIEIIC_01291 0.0 mtlR K Mga helix-turn-helix domain
HCMIEIIC_01292 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_01293 2.8e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCMIEIIC_01294 3.3e-149 S haloacid dehalogenase-like hydrolase
HCMIEIIC_01295 2.8e-44
HCMIEIIC_01296 2e-14
HCMIEIIC_01297 4.1e-136
HCMIEIIC_01298 4.4e-222 spiA K IrrE N-terminal-like domain
HCMIEIIC_01299 5.6e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCMIEIIC_01300 2e-126 V ABC transporter
HCMIEIIC_01301 8.1e-208 bacI V MacB-like periplasmic core domain
HCMIEIIC_01302 1.1e-90 1.6.5.5 C nadph quinone reductase
HCMIEIIC_01303 3.6e-74 K Helix-turn-helix XRE-family like proteins
HCMIEIIC_01304 6.4e-30
HCMIEIIC_01305 1.1e-180
HCMIEIIC_01306 0.0 M Leucine rich repeats (6 copies)
HCMIEIIC_01307 2.1e-231 M Leucine rich repeats (6 copies)
HCMIEIIC_01308 6.7e-223 mtnE 2.6.1.83 E Aminotransferase
HCMIEIIC_01309 1.4e-139 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HCMIEIIC_01310 2.7e-149 M NLPA lipoprotein
HCMIEIIC_01313 2.8e-60 K Psort location Cytoplasmic, score
HCMIEIIC_01314 1.7e-196 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
HCMIEIIC_01318 6.6e-81 yodP 2.3.1.264 K FR47-like protein
HCMIEIIC_01319 1.3e-81 ydcK S Belongs to the SprT family
HCMIEIIC_01320 2.8e-129 XK27_08845 S ABC transporter, ATP-binding protein
HCMIEIIC_01321 5.6e-129 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HCMIEIIC_01322 4e-176 XK27_08835 S ABC transporter
HCMIEIIC_01323 6.2e-73
HCMIEIIC_01324 0.0 pacL 3.6.3.8 P P-type ATPase
HCMIEIIC_01325 9.5e-189 S Bacterial protein of unknown function (DUF916)
HCMIEIIC_01326 8.4e-102
HCMIEIIC_01327 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HCMIEIIC_01328 2.3e-159 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HCMIEIIC_01329 1.2e-152 I alpha/beta hydrolase fold
HCMIEIIC_01330 1.3e-47
HCMIEIIC_01331 6.5e-69
HCMIEIIC_01332 7.9e-46
HCMIEIIC_01333 1e-156 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HCMIEIIC_01334 7.2e-124 citR K FCD
HCMIEIIC_01335 3.8e-265 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
HCMIEIIC_01336 5.2e-101 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HCMIEIIC_01337 9.8e-283 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HCMIEIIC_01338 2.6e-155 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HCMIEIIC_01339 2.2e-48 citD C Covalent carrier of the coenzyme of citrate lyase
HCMIEIIC_01340 4.2e-181 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HCMIEIIC_01342 1e-196 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
HCMIEIIC_01343 8.7e-37 gcdC 2.3.1.12 I Biotin-requiring enzyme
HCMIEIIC_01344 3.8e-51
HCMIEIIC_01345 1.4e-240 citM C Citrate transporter
HCMIEIIC_01346 1.3e-41
HCMIEIIC_01347 2.4e-95 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HCMIEIIC_01348 2.5e-86 K Acetyltransferase (GNAT) domain
HCMIEIIC_01349 3.9e-105 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HCMIEIIC_01350 1.8e-56 K Transcriptional regulator PadR-like family
HCMIEIIC_01351 4.6e-64 ORF00048
HCMIEIIC_01352 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HCMIEIIC_01353 1.1e-167 yjjC V ABC transporter
HCMIEIIC_01354 6.1e-283 M Exporter of polyketide antibiotics
HCMIEIIC_01355 8.9e-113 K Transcriptional regulator
HCMIEIIC_01356 6.5e-257 ypiB EGP Major facilitator Superfamily
HCMIEIIC_01357 1.1e-127 S membrane transporter protein
HCMIEIIC_01358 8.3e-185 K Helix-turn-helix domain
HCMIEIIC_01359 1.7e-159 S Alpha beta hydrolase
HCMIEIIC_01360 3.6e-61 yvoA_1 K Transcriptional regulator, GntR family
HCMIEIIC_01361 9.4e-127 skfE V ATPases associated with a variety of cellular activities
HCMIEIIC_01362 1.5e-12
HCMIEIIC_01365 5.3e-130 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HCMIEIIC_01366 9.6e-283 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HCMIEIIC_01367 3.9e-14 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HCMIEIIC_01368 1.6e-97
HCMIEIIC_01369 8.9e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
HCMIEIIC_01370 2.2e-177 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCMIEIIC_01371 2.2e-177 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCMIEIIC_01372 5.4e-44 ylxQ J ribosomal protein
HCMIEIIC_01373 1.5e-46 ylxR K Protein of unknown function (DUF448)
HCMIEIIC_01374 1e-202 nusA K Participates in both transcription termination and antitermination
HCMIEIIC_01375 1e-84 rimP J Required for maturation of 30S ribosomal subunits
HCMIEIIC_01376 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCMIEIIC_01377 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCMIEIIC_01378 4.1e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HCMIEIIC_01379 7.3e-141 cdsA 2.7.7.41 S Belongs to the CDS family
HCMIEIIC_01380 9.5e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCMIEIIC_01381 4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCMIEIIC_01382 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HCMIEIIC_01383 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCMIEIIC_01384 1.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HCMIEIIC_01385 1.3e-47 yazA L GIY-YIG catalytic domain protein
HCMIEIIC_01386 4.8e-134 yabB 2.1.1.223 L Methyltransferase small domain
HCMIEIIC_01387 2.2e-122 plsC 2.3.1.51 I Acyltransferase
HCMIEIIC_01388 5e-201 bcaP E Amino Acid
HCMIEIIC_01389 2.6e-138 yejC S Protein of unknown function (DUF1003)
HCMIEIIC_01390 0.0 mdlB V ABC transporter
HCMIEIIC_01391 0.0 mdlA V ABC transporter
HCMIEIIC_01392 4.8e-29 yneF S UPF0154 protein
HCMIEIIC_01393 1.1e-37 ynzC S UPF0291 protein
HCMIEIIC_01394 1.1e-25
HCMIEIIC_01395 7.4e-10 M Glycosyl hydrolase family 59
HCMIEIIC_01396 2.3e-27
HCMIEIIC_01397 0.0 yjbQ P TrkA C-terminal domain protein
HCMIEIIC_01398 3.2e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HCMIEIIC_01399 4.1e-68 yjhE S Phage tail protein
HCMIEIIC_01400 4.1e-216 mntH P H( )-stimulated, divalent metal cation uptake system
HCMIEIIC_01401 2.1e-182 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HCMIEIIC_01402 1.2e-128 pgm3 G Phosphoglycerate mutase family
HCMIEIIC_01403 3.2e-169 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HCMIEIIC_01404 0.0 V FtsX-like permease family
HCMIEIIC_01405 1.2e-135 cysA V ABC transporter, ATP-binding protein
HCMIEIIC_01406 0.0 E amino acid
HCMIEIIC_01407 5.3e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HCMIEIIC_01408 6.9e-237 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCMIEIIC_01409 5.7e-111 nodB3 G Polysaccharide deacetylase
HCMIEIIC_01410 0.0 M Sulfatase
HCMIEIIC_01411 3e-174 S EpsG family
HCMIEIIC_01412 7.4e-83 epsG 2.7.10.1 D Capsular exopolysaccharide family
HCMIEIIC_01413 1.4e-98 ywqC M capsule polysaccharide biosynthetic process
HCMIEIIC_01414 1.6e-247 S polysaccharide biosynthetic process
HCMIEIIC_01415 3.8e-199 M Glycosyl transferases group 1
HCMIEIIC_01416 1.8e-120 tagF 2.7.8.12 M Glycosyltransferase like family 2
HCMIEIIC_01417 1.3e-222 S Bacterial membrane protein, YfhO
HCMIEIIC_01418 2e-299 M Glycosyl hydrolases family 25
HCMIEIIC_01419 2.9e-178 M Dolichyl-phosphate-mannose-protein mannosyltransferase
HCMIEIIC_01420 1.9e-112 icaC M Acyltransferase family
HCMIEIIC_01421 1.9e-128 ykoT GT2 M Glycosyl transferase family 2
HCMIEIIC_01422 1.9e-198 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCMIEIIC_01423 8.1e-85
HCMIEIIC_01424 1.5e-253 wcaJ M Bacterial sugar transferase
HCMIEIIC_01425 1.4e-133 M Glycosyltransferase sugar-binding region containing DXD motif
HCMIEIIC_01426 6.9e-112 tuaG GT2 M Glycosyltransferase like family 2
HCMIEIIC_01427 9.2e-175 cps2D 5.1.3.2 M RmlD substrate binding domain
HCMIEIIC_01428 1.1e-110 glnP P ABC transporter permease
HCMIEIIC_01429 7.9e-109 gluC P ABC transporter permease
HCMIEIIC_01430 6.5e-148 glnH ET ABC transporter substrate-binding protein
HCMIEIIC_01432 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCMIEIIC_01433 1.3e-171
HCMIEIIC_01435 5.6e-85 zur P Belongs to the Fur family
HCMIEIIC_01436 1.8e-08
HCMIEIIC_01437 9.3e-112 gmk2 2.7.4.8 F Guanylate kinase
HCMIEIIC_01438 2.8e-67 K Acetyltransferase (GNAT) domain
HCMIEIIC_01439 5.6e-124 spl M NlpC/P60 family
HCMIEIIC_01440 2e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCMIEIIC_01441 2.6e-161 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCMIEIIC_01442 1.4e-53 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HCMIEIIC_01443 1.3e-173 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCMIEIIC_01444 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HCMIEIIC_01445 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCMIEIIC_01446 1.5e-285 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HCMIEIIC_01447 9.1e-22 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HCMIEIIC_01448 9.5e-155 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HCMIEIIC_01449 1.7e-197 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HCMIEIIC_01450 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HCMIEIIC_01451 1.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HCMIEIIC_01452 1.3e-112 ylcC 3.4.22.70 M Sortase family
HCMIEIIC_01453 3.4e-144 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCMIEIIC_01454 0.0 fbp 3.1.3.11 G phosphatase activity
HCMIEIIC_01455 5.7e-65 nrp 1.20.4.1 P ArsC family
HCMIEIIC_01456 0.0 clpL O associated with various cellular activities
HCMIEIIC_01457 7.6e-143 ywqE 3.1.3.48 GM PHP domain protein
HCMIEIIC_01458 2.4e-156 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HCMIEIIC_01459 5.6e-57 cpsE M Bacterial sugar transferase
HCMIEIIC_01460 1.5e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HCMIEIIC_01461 1.3e-201 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HCMIEIIC_01462 8.6e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HCMIEIIC_01463 2.2e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HCMIEIIC_01464 7.7e-63 wcmJ S SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
HCMIEIIC_01465 3.5e-52 cps1B GT2,GT4 M Glycosyl transferases group 1
HCMIEIIC_01466 6.6e-07 S EpsG family
HCMIEIIC_01467 2.5e-72 rgpB GT2 M Glycosyl transferase family 2
HCMIEIIC_01468 1.1e-25 rfbF GT2 V Glycosyl transferase, family 2
HCMIEIIC_01469 3.3e-43 wbbK M Glycosyl transferases group 1
HCMIEIIC_01470 8.9e-38 wbbL S Glycosyl transferase family 2
HCMIEIIC_01471 1.3e-41 cps2J S Polysaccharide biosynthesis protein
HCMIEIIC_01472 2.6e-111 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HCMIEIIC_01473 1.6e-68 yqeY S YqeY-like protein
HCMIEIIC_01474 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HCMIEIIC_01475 4.6e-64 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCMIEIIC_01476 2.3e-56 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCMIEIIC_01477 4.7e-168 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HCMIEIIC_01478 4.4e-169 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCMIEIIC_01479 1.1e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HCMIEIIC_01480 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HCMIEIIC_01481 1.4e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
HCMIEIIC_01482 1.3e-266
HCMIEIIC_01483 5.6e-158 V ABC transporter
HCMIEIIC_01484 1e-78 FG adenosine 5'-monophosphoramidase activity
HCMIEIIC_01485 5.2e-248 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
HCMIEIIC_01486 7.2e-115 3.1.3.18 J HAD-hyrolase-like
HCMIEIIC_01487 5.2e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCMIEIIC_01488 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCMIEIIC_01489 4e-53
HCMIEIIC_01490 3.9e-128 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCMIEIIC_01491 3e-173 prmA J Ribosomal protein L11 methyltransferase
HCMIEIIC_01492 2e-83 XK27_03960 S Protein of unknown function (DUF3013)
HCMIEIIC_01493 3.2e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HCMIEIIC_01494 3.1e-37
HCMIEIIC_01495 7e-60 S Protein of unknown function (DUF1093)
HCMIEIIC_01496 2.3e-26
HCMIEIIC_01497 6.3e-61
HCMIEIIC_01499 9.2e-112 1.6.5.2 S Flavodoxin-like fold
HCMIEIIC_01500 3.8e-91 K Bacterial regulatory proteins, tetR family
HCMIEIIC_01501 1.9e-186 mocA S Oxidoreductase
HCMIEIIC_01502 7.7e-278 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HCMIEIIC_01503 9.9e-299 2.4.1.52 GT4 M Glycosyl transferases group 1
HCMIEIIC_01505 1.3e-302 2.4.1.9, 3.4.24.40 GH68 S peptidase inhibitor activity
HCMIEIIC_01507 6.7e-287
HCMIEIIC_01508 8.5e-58
HCMIEIIC_01509 1.1e-124
HCMIEIIC_01510 3.3e-186
HCMIEIIC_01511 5.3e-147 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
HCMIEIIC_01512 1.2e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HCMIEIIC_01513 3.7e-90 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCMIEIIC_01514 2e-94 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCMIEIIC_01515 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HCMIEIIC_01516 7.1e-62
HCMIEIIC_01517 9.4e-83 6.3.3.2 S ASCH
HCMIEIIC_01518 5.9e-32
HCMIEIIC_01519 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCMIEIIC_01520 4.3e-154 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCMIEIIC_01521 1e-286 dnaK O Heat shock 70 kDa protein
HCMIEIIC_01522 5.2e-99 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCMIEIIC_01523 8.4e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCMIEIIC_01524 1.6e-224 hemN H Involved in the biosynthesis of porphyrin-containing compound
HCMIEIIC_01525 7.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HCMIEIIC_01526 1.3e-160 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCMIEIIC_01527 6.7e-119 terC P membrane
HCMIEIIC_01528 4.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCMIEIIC_01529 4.3e-152 aatB ET ABC transporter substrate-binding protein
HCMIEIIC_01530 1.7e-111 glnQ 3.6.3.21 E ABC transporter
HCMIEIIC_01531 4.7e-109 artQ P ABC transporter permease
HCMIEIIC_01532 1.1e-141 minD D Belongs to the ParA family
HCMIEIIC_01533 1.4e-113 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HCMIEIIC_01534 4.7e-83 mreD M rod shape-determining protein MreD
HCMIEIIC_01535 8.5e-151 mreC M Involved in formation and maintenance of cell shape
HCMIEIIC_01536 7.8e-180 mreB D cell shape determining protein MreB
HCMIEIIC_01537 2.7e-118 radC L DNA repair protein
HCMIEIIC_01538 1.3e-114 S Haloacid dehalogenase-like hydrolase
HCMIEIIC_01539 9.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HCMIEIIC_01540 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCMIEIIC_01541 1.5e-115 rex K CoA binding domain
HCMIEIIC_01542 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCMIEIIC_01543 2.1e-216 iscS2 2.8.1.7 E Aminotransferase class V
HCMIEIIC_01544 1.2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCMIEIIC_01545 1.5e-83 ytsP 1.8.4.14 T GAF domain-containing protein
HCMIEIIC_01546 2.1e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCMIEIIC_01548 2e-275 KL Helicase conserved C-terminal domain
HCMIEIIC_01549 1.9e-145 S Domain of unknown function (DUF1998)
HCMIEIIC_01550 1.1e-133 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HCMIEIIC_01551 5e-227 steT E Amino acid permease
HCMIEIIC_01552 1.9e-138 puuD S peptidase C26
HCMIEIIC_01553 0.0 yhgF K Tex-like protein N-terminal domain protein
HCMIEIIC_01554 2.2e-82 K Acetyltransferase (GNAT) domain
HCMIEIIC_01555 9.9e-150
HCMIEIIC_01556 2.5e-275
HCMIEIIC_01557 4.4e-158 yvfR V ABC transporter
HCMIEIIC_01558 1.6e-129 yvfS V ABC-2 type transporter
HCMIEIIC_01559 1.6e-197 desK 2.7.13.3 T Histidine kinase
HCMIEIIC_01560 4e-102 desR K helix_turn_helix, Lux Regulon
HCMIEIIC_01561 3.7e-106
HCMIEIIC_01562 1.4e-153 S Uncharacterised protein, DegV family COG1307
HCMIEIIC_01563 1.9e-15
HCMIEIIC_01564 1.5e-238 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HCMIEIIC_01565 2.3e-40 yozE S Belongs to the UPF0346 family
HCMIEIIC_01566 2.9e-78 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCMIEIIC_01567 5.8e-112 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HCMIEIIC_01568 7.8e-157 ypmR E GDSL-like Lipase/Acylhydrolase
HCMIEIIC_01569 4.3e-147 DegV S EDD domain protein, DegV family
HCMIEIIC_01570 2.1e-114 hly S protein, hemolysin III
HCMIEIIC_01571 7.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCMIEIIC_01572 7.5e-185 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCMIEIIC_01573 0.0 yfmR S ABC transporter, ATP-binding protein
HCMIEIIC_01574 9.6e-85
HCMIEIIC_01575 2.8e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCMIEIIC_01576 4.8e-149 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCMIEIIC_01577 1.7e-232 S Tetratricopeptide repeat protein
HCMIEIIC_01578 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCMIEIIC_01579 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HCMIEIIC_01580 1.1e-218 rpsA 1.17.7.4 J Ribosomal protein S1
HCMIEIIC_01581 2.6e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HCMIEIIC_01582 1.1e-54 M Lysin motif
HCMIEIIC_01583 1.3e-265 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HCMIEIIC_01584 1e-179 ypbB 5.1.3.1 S Helix-turn-helix domain
HCMIEIIC_01585 1.4e-45 fer C 4Fe-4S single cluster domain of Ferredoxin I
HCMIEIIC_01586 4.5e-95 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCMIEIIC_01587 6.1e-137 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCMIEIIC_01588 3.3e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCMIEIIC_01589 7.3e-127 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCMIEIIC_01590 3.4e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCMIEIIC_01591 3.3e-166 xerD D recombinase XerD
HCMIEIIC_01592 3.4e-163 cvfB S S1 domain
HCMIEIIC_01593 7.2e-72 yeaL S Protein of unknown function (DUF441)
HCMIEIIC_01594 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HCMIEIIC_01595 6.6e-176 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HCMIEIIC_01596 0.0 dnaE 2.7.7.7 L DNA polymerase
HCMIEIIC_01597 6e-20 S Protein of unknown function (DUF2929)
HCMIEIIC_01598 7.7e-144
HCMIEIIC_01599 1.9e-297 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
HCMIEIIC_01600 2.2e-54 M1-874 K Domain of unknown function (DUF1836)
HCMIEIIC_01601 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HCMIEIIC_01602 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCMIEIIC_01603 1.3e-46 yrvD S Lipopolysaccharide assembly protein A domain
HCMIEIIC_01604 1.4e-139 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HCMIEIIC_01605 9.4e-183 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCMIEIIC_01606 0.0 oatA I Acyltransferase
HCMIEIIC_01607 1.9e-234 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCMIEIIC_01608 7.7e-132 fruR K DeoR C terminal sensor domain
HCMIEIIC_01609 2.7e-155 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HCMIEIIC_01610 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HCMIEIIC_01611 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCMIEIIC_01612 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCMIEIIC_01613 1.6e-258 glnPH2 P ABC transporter permease
HCMIEIIC_01614 2.3e-20
HCMIEIIC_01615 1e-47 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HCMIEIIC_01616 3.1e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
HCMIEIIC_01617 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCMIEIIC_01618 1.2e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCMIEIIC_01619 0.0 yknV V ABC transporter
HCMIEIIC_01620 9.3e-65 rmeD K helix_turn_helix, mercury resistance
HCMIEIIC_01621 1.7e-63 pcaC 4.1.1.44 S Carboxymuconolactone decarboxylase family
HCMIEIIC_01622 1.4e-133 cobB K Sir2 family
HCMIEIIC_01623 2.2e-82 M Protein of unknown function (DUF3737)
HCMIEIIC_01624 1.2e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCMIEIIC_01625 1.6e-160 S Tetratricopeptide repeat
HCMIEIIC_01626 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCMIEIIC_01627 2.2e-117
HCMIEIIC_01628 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCMIEIIC_01629 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
HCMIEIIC_01630 2e-194 holA 2.7.7.7 L DNA polymerase III delta subunit
HCMIEIIC_01631 0.0 comEC S Competence protein ComEC
HCMIEIIC_01632 2.6e-107 comEA L Competence protein ComEA
HCMIEIIC_01633 3.6e-94 ylbL T Belongs to the peptidase S16 family
HCMIEIIC_01634 4.4e-90 ylbL T Belongs to the peptidase S16 family
HCMIEIIC_01635 2.8e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCMIEIIC_01636 1.7e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HCMIEIIC_01637 3.8e-57 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HCMIEIIC_01638 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HCMIEIIC_01639 1.9e-209 ftsW D Belongs to the SEDS family
HCMIEIIC_01640 0.0 typA T GTP-binding protein TypA
HCMIEIIC_01641 5e-145 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HCMIEIIC_01642 1.4e-46 yktA S Belongs to the UPF0223 family
HCMIEIIC_01643 7e-156 1.1.1.27 C L-malate dehydrogenase activity
HCMIEIIC_01644 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
HCMIEIIC_01645 3.7e-243 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCMIEIIC_01646 3.1e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HCMIEIIC_01647 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HCMIEIIC_01648 4.3e-136 S E1-E2 ATPase
HCMIEIIC_01649 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCMIEIIC_01650 1.9e-25
HCMIEIIC_01651 1.7e-73
HCMIEIIC_01653 4.9e-31 ykzG S Belongs to the UPF0356 family
HCMIEIIC_01654 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCMIEIIC_01655 6.5e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HCMIEIIC_01656 2.1e-243 els S Sterol carrier protein domain
HCMIEIIC_01657 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCMIEIIC_01658 4.5e-115 S Repeat protein
HCMIEIIC_01659 1.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HCMIEIIC_01660 8e-166 XK27_00670 S ABC transporter substrate binding protein
HCMIEIIC_01661 1.2e-164 XK27_00670 S ABC transporter
HCMIEIIC_01662 7.6e-156 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HCMIEIIC_01663 5.2e-142 cmpC S ABC transporter, ATP-binding protein
HCMIEIIC_01664 4.9e-171 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
HCMIEIIC_01665 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HCMIEIIC_01666 9.6e-183 ykcC GT2 M Glycosyl transferase family 2
HCMIEIIC_01667 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
HCMIEIIC_01668 7.1e-71 S GtrA-like protein
HCMIEIIC_01669 2.8e-08
HCMIEIIC_01670 2.2e-128 K cheY-homologous receiver domain
HCMIEIIC_01671 3.9e-240 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HCMIEIIC_01672 1.2e-67 yqkB S Belongs to the HesB IscA family
HCMIEIIC_01673 1.9e-121 drgA C Nitroreductase family
HCMIEIIC_01674 2.5e-203 lctO C IMP dehydrogenase / GMP reductase domain
HCMIEIIC_01677 6.4e-07 Z012_04635 K Helix-turn-helix domain
HCMIEIIC_01679 4.2e-06 mutR K Helix-turn-helix
HCMIEIIC_01681 1.4e-181 K sequence-specific DNA binding
HCMIEIIC_01682 3.1e-56 K Transcriptional regulator PadR-like family
HCMIEIIC_01683 4e-42 ygbF S Sugar efflux transporter for intercellular exchange
HCMIEIIC_01684 2.5e-49
HCMIEIIC_01685 1.1e-184 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HCMIEIIC_01686 4.8e-55
HCMIEIIC_01687 3.4e-80
HCMIEIIC_01688 7.4e-206 yubA S AI-2E family transporter
HCMIEIIC_01689 7.4e-26
HCMIEIIC_01690 3e-97 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCMIEIIC_01691 2.1e-74
HCMIEIIC_01692 2.9e-168 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HCMIEIIC_01693 1.5e-104 ywrF S Flavin reductase like domain
HCMIEIIC_01694 6.7e-96
HCMIEIIC_01695 1.4e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCMIEIIC_01696 3.3e-61 yeaO S Protein of unknown function, DUF488
HCMIEIIC_01697 6.6e-173 corA P CorA-like Mg2+ transporter protein
HCMIEIIC_01698 2.1e-160 mleR K LysR family
HCMIEIIC_01699 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HCMIEIIC_01700 1.1e-170 mleP S Sodium Bile acid symporter family
HCMIEIIC_01701 5.9e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCMIEIIC_01702 3.1e-95
HCMIEIIC_01703 6e-169 K sequence-specific DNA binding
HCMIEIIC_01704 1.7e-282 V ABC transporter transmembrane region
HCMIEIIC_01705 0.0 pepF E Oligopeptidase F
HCMIEIIC_01706 5e-78 ndk 2.7.4.6 F Belongs to the NDK family
HCMIEIIC_01707 1.3e-54
HCMIEIIC_01708 0.0 yfgQ P E1-E2 ATPase
HCMIEIIC_01709 2.3e-59 yfgQ P E1-E2 ATPase
HCMIEIIC_01710 8.8e-178 3.4.11.5 I Releases the N-terminal proline from various substrates
HCMIEIIC_01711 1.8e-59
HCMIEIIC_01712 4.6e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCMIEIIC_01713 3.6e-197 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCMIEIIC_01714 1.6e-120 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
HCMIEIIC_01715 1.5e-77 K Transcriptional regulator
HCMIEIIC_01716 3.6e-179 D Alpha beta
HCMIEIIC_01717 4.9e-84 nrdI F Belongs to the NrdI family
HCMIEIIC_01718 1.5e-157 dkgB S reductase
HCMIEIIC_01719 1.1e-120
HCMIEIIC_01720 3.4e-160 S Alpha beta hydrolase
HCMIEIIC_01721 2.3e-116 yviA S Protein of unknown function (DUF421)
HCMIEIIC_01722 3.5e-74 S Protein of unknown function (DUF3290)
HCMIEIIC_01723 5.7e-219 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HCMIEIIC_01724 1.6e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCMIEIIC_01725 4.6e-103 yjbF S SNARE associated Golgi protein
HCMIEIIC_01726 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCMIEIIC_01727 6.9e-195 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCMIEIIC_01728 9.5e-208 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HCMIEIIC_01729 1.1e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCMIEIIC_01730 3.9e-48 yajC U Preprotein translocase
HCMIEIIC_01731 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HCMIEIIC_01732 3.9e-116 sirR K Helix-turn-helix diphteria tox regulatory element
HCMIEIIC_01733 4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCMIEIIC_01734 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCMIEIIC_01735 5.2e-240 ytoI K DRTGG domain
HCMIEIIC_01736 5.3e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HCMIEIIC_01737 4.8e-249 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCMIEIIC_01738 1.4e-170
HCMIEIIC_01740 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCMIEIIC_01741 2.3e-201
HCMIEIIC_01742 1.2e-42 yrzL S Belongs to the UPF0297 family
HCMIEIIC_01743 2.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCMIEIIC_01744 2.3e-53 yrzB S Belongs to the UPF0473 family
HCMIEIIC_01745 2e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HCMIEIIC_01746 7.3e-92 cvpA S Colicin V production protein
HCMIEIIC_01747 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCMIEIIC_01748 6.6e-53 trxA O Belongs to the thioredoxin family
HCMIEIIC_01749 9.4e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCMIEIIC_01750 1.8e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
HCMIEIIC_01751 4e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCMIEIIC_01752 1.2e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HCMIEIIC_01753 1.1e-83 yslB S Protein of unknown function (DUF2507)
HCMIEIIC_01754 2.6e-277 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HCMIEIIC_01755 1.2e-94 S Phosphoesterase
HCMIEIIC_01756 8.9e-133 gla U Major intrinsic protein
HCMIEIIC_01757 8.7e-84 ykuL S CBS domain
HCMIEIIC_01758 4.2e-156 XK27_00890 S Domain of unknown function (DUF368)
HCMIEIIC_01759 1.2e-155 ykuT M mechanosensitive ion channel
HCMIEIIC_01762 4.9e-74 ytxH S YtxH-like protein
HCMIEIIC_01763 1.9e-92 niaR S 3H domain
HCMIEIIC_01764 7.5e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HCMIEIIC_01765 2.3e-179 ccpA K catabolite control protein A
HCMIEIIC_01766 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
HCMIEIIC_01767 1.9e-07
HCMIEIIC_01768 3.2e-24 smc D Required for chromosome condensation and partitioning
HCMIEIIC_01769 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCMIEIIC_01770 0.0 uvrA2 L ABC transporter
HCMIEIIC_01771 2.6e-58 XK27_04120 S Putative amino acid metabolism
HCMIEIIC_01772 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
HCMIEIIC_01773 2.4e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCMIEIIC_01774 5.8e-34
HCMIEIIC_01775 7e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HCMIEIIC_01776 7.6e-115 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HCMIEIIC_01777 1.8e-207 yaaN P Toxic anion resistance protein (TelA)
HCMIEIIC_01778 5.2e-262 ydiC1 EGP Major facilitator Superfamily
HCMIEIIC_01779 1.5e-145 pstS P Phosphate
HCMIEIIC_01780 8.2e-37 cspA K Cold shock protein
HCMIEIIC_01781 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCMIEIIC_01782 1.1e-80 divIVA D DivIVA protein
HCMIEIIC_01783 6.4e-145 ylmH S S4 domain protein
HCMIEIIC_01784 5.2e-44 yggT D integral membrane protein
HCMIEIIC_01785 6.7e-78 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCMIEIIC_01786 5.4e-218 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCMIEIIC_01787 7.6e-223 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCMIEIIC_01788 1.3e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCMIEIIC_01789 9.7e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCMIEIIC_01790 3.9e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCMIEIIC_01791 9.2e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCMIEIIC_01792 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HCMIEIIC_01793 6.2e-58 ftsL D cell division protein FtsL
HCMIEIIC_01794 5.3e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCMIEIIC_01795 4.8e-78 mraZ K Belongs to the MraZ family
HCMIEIIC_01796 4.2e-53
HCMIEIIC_01797 8.9e-289 2.4.1.52 GT4 M Glycosyl transferases group 1
HCMIEIIC_01798 3.3e-302 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HCMIEIIC_01799 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HCMIEIIC_01800 2.7e-94 yqaB S Acetyltransferase (GNAT) domain
HCMIEIIC_01801 1.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCMIEIIC_01802 4.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCMIEIIC_01803 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HCMIEIIC_01804 2.1e-266 nylA 3.5.1.4 J Belongs to the amidase family
HCMIEIIC_01805 3.4e-89 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
HCMIEIIC_01806 6.1e-86 S ECF transporter, substrate-specific component
HCMIEIIC_01807 3.1e-63 S Domain of unknown function (DUF4430)
HCMIEIIC_01808 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HCMIEIIC_01809 3.8e-78 F nucleoside 2-deoxyribosyltransferase
HCMIEIIC_01810 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
HCMIEIIC_01811 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
HCMIEIIC_01812 1.5e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCMIEIIC_01813 8.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HCMIEIIC_01814 3.2e-170 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HCMIEIIC_01815 1.1e-164 menA 2.5.1.74 M UbiA prenyltransferase family
HCMIEIIC_01817 2e-194 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCMIEIIC_01819 5e-206 gntP EG Gluconate
HCMIEIIC_01820 4.9e-57
HCMIEIIC_01821 4.1e-130 fhuC 3.6.3.35 P ABC transporter
HCMIEIIC_01822 3.3e-133 znuB U ABC 3 transport family
HCMIEIIC_01823 6.4e-167 T Calcineurin-like phosphoesterase superfamily domain
HCMIEIIC_01824 2.3e-159 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HCMIEIIC_01825 0.0 pepF E oligoendopeptidase F
HCMIEIIC_01826 2e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HCMIEIIC_01827 2.3e-246 brnQ U Component of the transport system for branched-chain amino acids
HCMIEIIC_01828 4.5e-70 T Sh3 type 3 domain protein
HCMIEIIC_01829 2.2e-134 glcR K DeoR C terminal sensor domain
HCMIEIIC_01830 7.5e-146 M Glycosyltransferase like family 2
HCMIEIIC_01831 5.3e-133 XK27_06755 S Protein of unknown function (DUF975)
HCMIEIIC_01832 6.4e-52
HCMIEIIC_01833 2e-107 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HCMIEIIC_01834 7.8e-174 draG O ADP-ribosylglycohydrolase
HCMIEIIC_01835 4.7e-293 S ABC transporter
HCMIEIIC_01836 8.5e-139 ksgA 2.1.1.182, 2.1.1.197, 2.5.1.134 J rRNA (adenine-N6,N6-)-dimethyltransferase activity
HCMIEIIC_01837 6.2e-73
HCMIEIIC_01838 0.0 pacL 3.6.3.8 P P-type ATPase
HCMIEIIC_01839 7.8e-216 V Beta-lactamase
HCMIEIIC_01840 3.7e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCMIEIIC_01841 1.3e-221 V Beta-lactamase
HCMIEIIC_01842 6.1e-274 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCMIEIIC_01843 6.6e-125 gntR1 K UbiC transcription regulator-associated domain protein
HCMIEIIC_01844 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCMIEIIC_01845 1.3e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCMIEIIC_01846 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
HCMIEIIC_01847 4.5e-271 sprD D Domain of Unknown Function (DUF1542)
HCMIEIIC_01848 1.9e-275 mga K Mga helix-turn-helix domain
HCMIEIIC_01850 5.4e-119 yjjH S Calcineurin-like phosphoesterase
HCMIEIIC_01851 1.2e-256 dtpT U amino acid peptide transporter
HCMIEIIC_01852 2.4e-122 macB_3 V ABC transporter, ATP-binding protein
HCMIEIIC_01853 1.4e-276 macB_3 V ABC transporter, ATP-binding protein
HCMIEIIC_01854 1.4e-65
HCMIEIIC_01855 2.1e-73 S function, without similarity to other proteins
HCMIEIIC_01856 9.9e-261 G MFS/sugar transport protein
HCMIEIIC_01857 1e-231 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
HCMIEIIC_01858 1e-56
HCMIEIIC_01859 0.0 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
HCMIEIIC_01860 2.7e-24 S Virus attachment protein p12 family
HCMIEIIC_01861 1.2e-247 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HCMIEIIC_01862 4.3e-141 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HCMIEIIC_01863 5.2e-99 feoA P FeoA
HCMIEIIC_01864 5.2e-106 E lipolytic protein G-D-S-L family
HCMIEIIC_01865 3.5e-88 E AAA domain
HCMIEIIC_01868 2.9e-119 ywnB S NAD(P)H-binding
HCMIEIIC_01869 1.1e-91 S MucBP domain
HCMIEIIC_01870 1.3e-85
HCMIEIIC_01872 1e-171 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HCMIEIIC_01873 1.1e-150 yunF F Protein of unknown function DUF72
HCMIEIIC_01874 1.1e-91 3.6.1.55 F NUDIX domain
HCMIEIIC_01875 1.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HCMIEIIC_01876 5.3e-107 yiiE S Protein of unknown function (DUF1211)
HCMIEIIC_01877 2.2e-128 cobB K Sir2 family
HCMIEIIC_01878 1.2e-07
HCMIEIIC_01879 5.7e-169
HCMIEIIC_01880 1.9e-97 yxkA S Phosphatidylethanolamine-binding protein
HCMIEIIC_01882 4.2e-162 ypuA S Protein of unknown function (DUF1002)
HCMIEIIC_01883 2.5e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HCMIEIIC_01884 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HCMIEIIC_01885 2.8e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HCMIEIIC_01886 3e-173 S Aldo keto reductase
HCMIEIIC_01887 9.3e-155 bioC 2.1.1.187, 2.1.1.197 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HCMIEIIC_01888 1.7e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HCMIEIIC_01889 1e-238 dinF V MatE
HCMIEIIC_01890 1.2e-109 S TPM domain
HCMIEIIC_01891 3.1e-102 lemA S LemA family
HCMIEIIC_01892 5.3e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCMIEIIC_01893 9.2e-74 EGP Major Facilitator Superfamily
HCMIEIIC_01894 1.9e-250 gshR 1.8.1.7 C Glutathione reductase
HCMIEIIC_01895 1.7e-176 proV E ABC transporter, ATP-binding protein
HCMIEIIC_01896 2.6e-275 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCMIEIIC_01897 0.0 helD 3.6.4.12 L DNA helicase
HCMIEIIC_01898 1.5e-147 rlrG K Transcriptional regulator
HCMIEIIC_01899 1.1e-175 shetA P Voltage-dependent anion channel
HCMIEIIC_01900 5.7e-248 bmr3 EGP Major facilitator Superfamily
HCMIEIIC_01901 1e-136 magIII L Base excision DNA repair protein, HhH-GPD family
HCMIEIIC_01902 1.3e-159 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
HCMIEIIC_01903 7.3e-242 sgaT 2.7.1.194 S PTS system sugar-specific permease component
HCMIEIIC_01904 6.4e-162 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HCMIEIIC_01905 2.1e-285 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HCMIEIIC_01906 3.2e-133 K DeoR C terminal sensor domain
HCMIEIIC_01907 1.2e-216 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCMIEIIC_01908 2.7e-252 rarA L recombination factor protein RarA
HCMIEIIC_01909 7.4e-55
HCMIEIIC_01910 5.4e-149 yhaI S Protein of unknown function (DUF805)
HCMIEIIC_01911 3.8e-271 L Mga helix-turn-helix domain
HCMIEIIC_01913 1.1e-182 ynjC S Cell surface protein
HCMIEIIC_01914 4.1e-123 yqcC S WxL domain surface cell wall-binding
HCMIEIIC_01916 0.0
HCMIEIIC_01917 5.6e-106 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCMIEIIC_01918 1e-42
HCMIEIIC_01919 5.8e-188 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCMIEIIC_01920 9e-53 S DsrE/DsrF-like family
HCMIEIIC_01921 1.4e-254 pbuO S permease
HCMIEIIC_01922 5.2e-54 S Protein of unknown function (DUF1516)
HCMIEIIC_01923 2.4e-57 ypaA S Protein of unknown function (DUF1304)
HCMIEIIC_01924 5.6e-41
HCMIEIIC_01926 4.7e-08 ssb_2 L Single-strand binding protein family
HCMIEIIC_01927 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCMIEIIC_01928 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCMIEIIC_01929 7.3e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCMIEIIC_01930 2.9e-31 yaaA S S4 domain protein YaaA
HCMIEIIC_01932 5.2e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCMIEIIC_01933 3.5e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCMIEIIC_01934 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HCMIEIIC_01935 1.9e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCMIEIIC_01936 5.6e-134 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCMIEIIC_01937 1.3e-137 jag S R3H domain protein
HCMIEIIC_01938 1.4e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCMIEIIC_01939 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCMIEIIC_01940 2.3e-274 V ABC transporter transmembrane region
HCMIEIIC_01941 7.2e-30
HCMIEIIC_01943 3.2e-133 thrE S Putative threonine/serine exporter
HCMIEIIC_01944 2.6e-80 S Threonine/Serine exporter, ThrE
HCMIEIIC_01945 2e-222 amd 3.5.1.47 E Peptidase family M20/M25/M40
HCMIEIIC_01947 2.1e-133
HCMIEIIC_01948 2.8e-252 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCMIEIIC_01949 1.3e-16 S Short C-terminal domain
HCMIEIIC_01950 4.5e-216 yqiG C Oxidoreductase
HCMIEIIC_01951 7.1e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCMIEIIC_01952 1.7e-179 S Aldo keto reductase
HCMIEIIC_01953 1.9e-53 S Enterocin A Immunity
HCMIEIIC_01954 2.4e-53
HCMIEIIC_01955 6.4e-252 EGP Major Facilitator Superfamily
HCMIEIIC_01956 9.3e-69 K Transcriptional regulator
HCMIEIIC_01957 4.4e-133 S CAAX protease self-immunity
HCMIEIIC_01961 5.8e-21
HCMIEIIC_01962 1.9e-44 spiA S Enterocin A Immunity
HCMIEIIC_01963 7.3e-133 plnD K LytTr DNA-binding domain
HCMIEIIC_01964 3.3e-218 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HCMIEIIC_01966 7.9e-17 L Transposase DDE domain
HCMIEIIC_01967 5.2e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
HCMIEIIC_01968 2.6e-135 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCMIEIIC_01969 4.2e-272 pepV 3.5.1.18 E dipeptidase PepV
HCMIEIIC_01970 2.6e-255 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HCMIEIIC_01971 2.1e-54
HCMIEIIC_01972 6.4e-188 yibE S overlaps another CDS with the same product name
HCMIEIIC_01973 5.9e-116 yibF S overlaps another CDS with the same product name
HCMIEIIC_01974 1.8e-115 S Calcineurin-like phosphoesterase
HCMIEIIC_01975 1.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HCMIEIIC_01976 8.8e-110 yutD S Protein of unknown function (DUF1027)
HCMIEIIC_01977 1.4e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCMIEIIC_01978 5.6e-115 S Protein of unknown function (DUF1461)
HCMIEIIC_01979 2.3e-116 dedA S SNARE-like domain protein
HCMIEIIC_01980 1.5e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HCMIEIIC_01981 7.9e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HCMIEIIC_01982 3.8e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCMIEIIC_01983 1.3e-63 yugI 5.3.1.9 J general stress protein
HCMIEIIC_01984 6.1e-35
HCMIEIIC_01985 1.2e-61 S Glycine-rich SFCGS
HCMIEIIC_01986 1.7e-52 S Domain of unknown function (DUF4312)
HCMIEIIC_01987 1.7e-137 S Domain of unknown function (DUF4311)
HCMIEIIC_01988 1e-106 S Domain of unknown function (DUF4310)
HCMIEIIC_01989 2.2e-215 dho 3.5.2.3 S Amidohydrolase family
HCMIEIIC_01990 1.2e-202 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
HCMIEIIC_01991 1.1e-136 4.1.2.14 S KDGP aldolase
HCMIEIIC_01993 2e-09 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCMIEIIC_01994 5.2e-60 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCMIEIIC_01995 7e-125 K Helix-turn-helix domain, rpiR family
HCMIEIIC_01996 6.9e-108 K Transcriptional activator, Rgg GadR MutR family
HCMIEIIC_01997 8.3e-208 V ABC-type multidrug transport system, ATPase and permease components
HCMIEIIC_01998 3.6e-296 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HCMIEIIC_01999 7.8e-271 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HCMIEIIC_02000 4.6e-53 araR K Transcriptional regulator
HCMIEIIC_02001 2.7e-22 2.7.1.191 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HCMIEIIC_02002 4.4e-64 G PTS system sorbose-specific iic component
HCMIEIIC_02003 3.1e-65 G PTS system mannose/fructose/sorbose family IID component
HCMIEIIC_02004 2.7e-40 2.7.1.191 G PTS system sorbose subfamily IIB component
HCMIEIIC_02005 6.3e-65 K UTRA
HCMIEIIC_02006 8e-287 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCMIEIIC_02007 1.6e-252 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCMIEIIC_02008 8e-85
HCMIEIIC_02009 5.8e-52 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HCMIEIIC_02010 2.9e-48 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_02011 1.4e-189 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCMIEIIC_02012 4.3e-91 ogt 2.1.1.63 L Methyltransferase
HCMIEIIC_02013 1.6e-120 K Transcriptional regulatory protein, C terminal
HCMIEIIC_02014 1.5e-200 T PhoQ Sensor
HCMIEIIC_02015 5.7e-86
HCMIEIIC_02016 7.8e-226 EGP Major facilitator Superfamily
HCMIEIIC_02017 3.8e-111
HCMIEIIC_02018 2.1e-39
HCMIEIIC_02019 1.1e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HCMIEIIC_02020 7.3e-42
HCMIEIIC_02021 1.2e-207 mccF V LD-carboxypeptidase
HCMIEIIC_02022 4.8e-182 yveB 2.7.4.29 I PAP2 superfamily
HCMIEIIC_02023 3e-111 K Bacteriophage CI repressor helix-turn-helix domain
HCMIEIIC_02024 7.7e-51
HCMIEIIC_02025 9.7e-30
HCMIEIIC_02026 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HCMIEIIC_02027 2.2e-102 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HCMIEIIC_02028 6.5e-120 yxlF V ABC transporter
HCMIEIIC_02029 1.6e-26 S Phospholipase_D-nuclease N-terminal
HCMIEIIC_02030 5.3e-153 K Helix-turn-helix XRE-family like proteins
HCMIEIIC_02031 5.5e-204 yxaM EGP Major facilitator Superfamily
HCMIEIIC_02032 1.3e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HCMIEIIC_02033 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HCMIEIIC_02035 4.9e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCMIEIIC_02036 6.7e-206 4.1.1.52 S Amidohydrolase
HCMIEIIC_02037 0.0 ylbB V ABC transporter permease
HCMIEIIC_02038 5.4e-127 V ABC transporter, ATP-binding protein
HCMIEIIC_02039 1.7e-105 K Transcriptional regulator C-terminal region
HCMIEIIC_02040 7.5e-155 K Helix-turn-helix domain, rpiR family
HCMIEIIC_02041 1.9e-197 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HCMIEIIC_02042 1.5e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HCMIEIIC_02043 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCMIEIIC_02044 2.1e-221
HCMIEIIC_02045 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HCMIEIIC_02046 5.1e-70 rplI J Binds to the 23S rRNA
HCMIEIIC_02047 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HCMIEIIC_02048 7.5e-100 V ABC transporter, ATP-binding protein
HCMIEIIC_02049 6.8e-80 P ABC-2 family transporter protein
HCMIEIIC_02050 1.5e-55 V ABC-2 type transporter
HCMIEIIC_02051 6.8e-60 K Tetracyclin repressor, C-terminal all-alpha domain
HCMIEIIC_02052 1.4e-105 L PFAM transposase, IS4 family protein
HCMIEIIC_02053 2.1e-51 L PFAM transposase, IS4 family protein
HCMIEIIC_02055 1.1e-150 EG EamA-like transporter family
HCMIEIIC_02056 5e-72 3.6.1.55 L NUDIX domain
HCMIEIIC_02057 8e-61
HCMIEIIC_02058 9.7e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCMIEIIC_02059 5.6e-186 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCMIEIIC_02060 4.4e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
HCMIEIIC_02061 5.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCMIEIIC_02062 2.2e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCMIEIIC_02063 4.9e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCMIEIIC_02064 3.1e-159 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCMIEIIC_02065 7.7e-135 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCMIEIIC_02066 4.4e-106 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
HCMIEIIC_02067 1.7e-53
HCMIEIIC_02068 2.1e-99 V ATPases associated with a variety of cellular activities
HCMIEIIC_02069 1.3e-109
HCMIEIIC_02070 8e-158 S ABC-type transport system involved in multi-copper enzyme maturation permease component
HCMIEIIC_02071 4.3e-116
HCMIEIIC_02072 8.8e-110 K Bacterial regulatory proteins, tetR family
HCMIEIIC_02073 2.1e-300 norB EGP Major Facilitator
HCMIEIIC_02075 3.2e-181 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HCMIEIIC_02076 2.8e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HCMIEIIC_02077 3.2e-104 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HCMIEIIC_02078 2.7e-227 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HCMIEIIC_02079 5.2e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HCMIEIIC_02081 4e-156 bglK_1 2.7.1.2 GK ROK family
HCMIEIIC_02082 2.6e-274 bgl 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCMIEIIC_02083 3.1e-139 K SIS domain
HCMIEIIC_02084 0.0 mngB 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HCMIEIIC_02085 1.6e-79 frvA 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCMIEIIC_02086 2.2e-250 manY 2.7.1.191, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HCMIEIIC_02087 6.3e-157 S CAAX protease self-immunity
HCMIEIIC_02089 3.1e-116 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HCMIEIIC_02090 3.6e-100 dps P Belongs to the Dps family
HCMIEIIC_02091 5.6e-33 copZ P Heavy-metal-associated domain
HCMIEIIC_02092 0.0 3.6.3.3, 3.6.3.5 P P-type ATPase
HCMIEIIC_02093 1.2e-214 opuCA E ABC transporter, ATP-binding protein
HCMIEIIC_02094 4.7e-106 opuCB E ABC transporter permease
HCMIEIIC_02095 1.6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCMIEIIC_02096 1.9e-110 opuCD P Binding-protein-dependent transport system inner membrane component
HCMIEIIC_02098 1e-148 S Protein of unknown function (DUF3100)
HCMIEIIC_02099 1.9e-69 S An automated process has identified a potential problem with this gene model
HCMIEIIC_02100 2.9e-243 3.5.4.28, 3.5.4.31 F Amidohydrolase family
HCMIEIIC_02101 9.1e-120 S Sulfite exporter TauE/SafE
HCMIEIIC_02102 1e-105 K Tetracycline repressor, C-terminal all-alpha domain
HCMIEIIC_02103 0.0 ydgH S MMPL family
HCMIEIIC_02105 1.6e-46 K Bacterial regulatory proteins, tetR family
HCMIEIIC_02106 2.8e-09 L Transposase and inactivated derivatives, IS30 family
HCMIEIIC_02107 2.7e-213 L Belongs to the 'phage' integrase family
HCMIEIIC_02108 1e-09
HCMIEIIC_02109 4.8e-21
HCMIEIIC_02110 1.1e-97 3.1.21.3 V Type I restriction modification DNA specificity domain
HCMIEIIC_02111 5.8e-19 3.4.21.88 K Peptidase S24-like
HCMIEIIC_02112 5.1e-39 3.4.21.88 K Helix-turn-helix
HCMIEIIC_02113 3.9e-09 K Helix-turn-helix XRE-family like proteins
HCMIEIIC_02114 1.1e-29 kilA K BRO family, N-terminal domain
HCMIEIIC_02115 1.1e-82 S Phage regulatory protein Rha (Phage_pRha)
HCMIEIIC_02122 3.9e-100 S calcium ion binding
HCMIEIIC_02123 3.8e-232 S DNA helicase activity
HCMIEIIC_02126 5.8e-39
HCMIEIIC_02127 3e-65 S magnesium ion binding
HCMIEIIC_02128 7.2e-19
HCMIEIIC_02129 5.4e-26
HCMIEIIC_02130 6.3e-93 S Protein of unknown function (DUF1642)
HCMIEIIC_02132 1.2e-33
HCMIEIIC_02134 9.1e-77
HCMIEIIC_02135 1.4e-12
HCMIEIIC_02136 3.2e-236
HCMIEIIC_02137 8.8e-98 S HNH endonuclease
HCMIEIIC_02138 4.9e-51
HCMIEIIC_02139 2.5e-72 S HNH endonuclease
HCMIEIIC_02140 8.7e-78 S Phage terminase, small subunit
HCMIEIIC_02141 1.4e-64 S Phage Terminase
HCMIEIIC_02142 4.9e-229 S Phage Terminase
HCMIEIIC_02143 7.7e-214 S Phage portal protein
HCMIEIIC_02144 2.3e-105 S peptidase activity
HCMIEIIC_02145 6.2e-208 S peptidase activity
HCMIEIIC_02146 8e-22 S peptidase activity
HCMIEIIC_02147 3.6e-26 S Phage gp6-like head-tail connector protein
HCMIEIIC_02148 5.2e-40 S Phage head-tail joining protein
HCMIEIIC_02149 2.9e-66 S exonuclease activity
HCMIEIIC_02150 2.9e-29
HCMIEIIC_02151 9.3e-75 S Pfam:Phage_TTP_1
HCMIEIIC_02152 1.8e-21
HCMIEIIC_02153 0.0 S peptidoglycan catabolic process
HCMIEIIC_02154 7.8e-41 S phage tail
HCMIEIIC_02155 2.7e-51 S Prophage endopeptidase tail
HCMIEIIC_02156 1.2e-56 cotH M CotH kinase protein
HCMIEIIC_02157 6.1e-48
HCMIEIIC_02158 9.8e-44 hol S Bacteriophage holin
HCMIEIIC_02159 2.1e-31
HCMIEIIC_02160 3.5e-203 M Glycosyl hydrolases family 25
HCMIEIIC_02161 6.7e-09 icaC G Acyltransferase family
HCMIEIIC_02162 5.3e-80 perR P Belongs to the Fur family
HCMIEIIC_02163 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCMIEIIC_02164 5.1e-44 ykuJ S Protein of unknown function (DUF1797)
HCMIEIIC_02165 1.2e-219 patA 2.6.1.1 E Aminotransferase
HCMIEIIC_02166 2.9e-166 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCMIEIIC_02167 2.6e-194 cpoA GT4 M Glycosyltransferase, group 1 family protein
HCMIEIIC_02168 4.5e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HCMIEIIC_02169 1.1e-297 ybeC E amino acid
HCMIEIIC_02170 5.1e-72 sigH K Sigma-70 region 2
HCMIEIIC_02196 3.9e-53
HCMIEIIC_02197 4.9e-148 recO L Involved in DNA repair and RecF pathway recombination
HCMIEIIC_02198 1.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCMIEIIC_02199 1.8e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HCMIEIIC_02200 1.5e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HCMIEIIC_02201 6.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCMIEIIC_02202 5.5e-178 phoH T phosphate starvation-inducible protein PhoH
HCMIEIIC_02203 1.6e-68 yqeY S YqeY-like protein
HCMIEIIC_02204 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HCMIEIIC_02205 3.4e-132 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCMIEIIC_02206 4.7e-168 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HCMIEIIC_02207 4.4e-169 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCMIEIIC_02208 1.1e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HCMIEIIC_02209 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HCMIEIIC_02210 1.1e-56 hisS 6.1.1.21 J histidyl-tRNA synthetase
HCMIEIIC_02211 1.5e-53 S PRD domain
HCMIEIIC_02212 0.0 K Mga helix-turn-helix domain
HCMIEIIC_02213 2.9e-122 tal 2.2.1.2 H Pfam:Transaldolase
HCMIEIIC_02214 3.9e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HCMIEIIC_02215 1.6e-194 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HCMIEIIC_02216 2.2e-102 srlA G PTS system enzyme II sorbitol-specific factor
HCMIEIIC_02217 1.4e-87 gutM K Glucitol operon activator protein (GutM)
HCMIEIIC_02218 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HCMIEIIC_02219 2.5e-144 IQ NAD dependent epimerase/dehydratase family
HCMIEIIC_02220 5.2e-116 ywnB S NmrA-like family
HCMIEIIC_02221 1.5e-06
HCMIEIIC_02222 2.7e-199
HCMIEIIC_02223 1.9e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HCMIEIIC_02224 1.7e-88 S Short repeat of unknown function (DUF308)
HCMIEIIC_02226 5.9e-121 yrkL S Flavodoxin-like fold
HCMIEIIC_02227 7.4e-149 cytC6 I alpha/beta hydrolase fold
HCMIEIIC_02228 7.5e-209 mutY L A G-specific adenine glycosylase
HCMIEIIC_02229 3.1e-86 hsp1 O Belongs to the small heat shock protein (HSP20) family
HCMIEIIC_02230 4e-09
HCMIEIIC_02231 6.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCMIEIIC_02232 3.1e-147 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HCMIEIIC_02233 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCMIEIIC_02234 8.4e-38 ylqC S Belongs to the UPF0109 family
HCMIEIIC_02235 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HCMIEIIC_02236 1.2e-229 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCMIEIIC_02237 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCMIEIIC_02238 6.8e-24
HCMIEIIC_02239 8.8e-53
HCMIEIIC_02240 1.3e-182 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCMIEIIC_02241 0.0 smc D Required for chromosome condensation and partitioning
HCMIEIIC_02242 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCMIEIIC_02243 0.0 oppA1 E ABC transporter substrate-binding protein
HCMIEIIC_02244 8.2e-136 oppC EP Binding-protein-dependent transport system inner membrane component
HCMIEIIC_02245 2.8e-174 oppB P ABC transporter permease
HCMIEIIC_02246 5.3e-178 oppF P Belongs to the ABC transporter superfamily
HCMIEIIC_02247 4.4e-194 oppD P Belongs to the ABC transporter superfamily
HCMIEIIC_02248 8.9e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCMIEIIC_02249 1.5e-186 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCMIEIIC_02250 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCMIEIIC_02251 4.7e-286 yloV S DAK2 domain fusion protein YloV
HCMIEIIC_02252 2.3e-57 asp S Asp23 family, cell envelope-related function
HCMIEIIC_02253 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HCMIEIIC_02254 1.3e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
HCMIEIIC_02255 3.7e-114 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HCMIEIIC_02256 1.6e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCMIEIIC_02257 0.0 KLT serine threonine protein kinase
HCMIEIIC_02258 4.8e-134 stp 3.1.3.16 T phosphatase
HCMIEIIC_02259 1.1e-250 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCMIEIIC_02260 1.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCMIEIIC_02261 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCMIEIIC_02262 3.4e-181 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCMIEIIC_02263 2.9e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCMIEIIC_02264 4.7e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HCMIEIIC_02265 4.7e-120 rssA S Patatin-like phospholipase
HCMIEIIC_02266 6e-51
HCMIEIIC_02267 5.7e-308 recN L May be involved in recombinational repair of damaged DNA
HCMIEIIC_02268 2e-74 argR K Regulates arginine biosynthesis genes
HCMIEIIC_02269 5.2e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HCMIEIIC_02270 1.8e-145 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCMIEIIC_02271 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCMIEIIC_02272 2.1e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCMIEIIC_02273 5e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCMIEIIC_02274 2e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCMIEIIC_02275 1.5e-72 yqhY S Asp23 family, cell envelope-related function
HCMIEIIC_02276 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCMIEIIC_02277 7e-203 ypdF 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HCMIEIIC_02278 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HCMIEIIC_02279 1.2e-55 ysxB J Cysteine protease Prp
HCMIEIIC_02280 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HCMIEIIC_02281 3.8e-32
HCMIEIIC_02282 4.1e-14
HCMIEIIC_02283 2.5e-233 ywhK S Membrane
HCMIEIIC_02285 1.1e-263 V ABC transporter transmembrane region
HCMIEIIC_02286 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HCMIEIIC_02287 5.8e-263 glnA 6.3.1.2 E glutamine synthetase
HCMIEIIC_02288 1e-60 glnR K Transcriptional regulator
HCMIEIIC_02289 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HCMIEIIC_02290 6.5e-240 ynbB 4.4.1.1 P aluminum resistance
HCMIEIIC_02291 5.7e-180 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCMIEIIC_02292 4.9e-24 WQ51_02665 S Protein of unknown function (DUF3042)
HCMIEIIC_02293 3.7e-72 yqhL P Rhodanese-like protein
HCMIEIIC_02294 2e-177 glk 2.7.1.2 G Glucokinase
HCMIEIIC_02295 1.1e-40 yqgQ S Bacterial protein of unknown function (DUF910)
HCMIEIIC_02296 9.6e-121 gluP 3.4.21.105 S Peptidase, S54 family
HCMIEIIC_02297 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HCMIEIIC_02298 0.0 S Bacterial membrane protein YfhO
HCMIEIIC_02299 2.9e-53 yneR S Belongs to the HesB IscA family
HCMIEIIC_02300 2.5e-113 vraR K helix_turn_helix, Lux Regulon
HCMIEIIC_02301 2.5e-170 vraS 2.7.13.3 T Histidine kinase
HCMIEIIC_02302 8.9e-122 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HCMIEIIC_02303 9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCMIEIIC_02304 6.9e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HCMIEIIC_02305 1.5e-206 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCMIEIIC_02306 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCMIEIIC_02307 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCMIEIIC_02308 2.6e-67 yodB K Transcriptional regulator, HxlR family
HCMIEIIC_02309 5.6e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCMIEIIC_02310 1.1e-136 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCMIEIIC_02311 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HCMIEIIC_02312 4.5e-180 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCMIEIIC_02313 5.2e-287 arlS 2.7.13.3 T Histidine kinase
HCMIEIIC_02314 7.9e-123 K response regulator
HCMIEIIC_02315 7.2e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCMIEIIC_02316 1.6e-94 yceD S Uncharacterized ACR, COG1399
HCMIEIIC_02317 5.5e-206 ylbM S Belongs to the UPF0348 family
HCMIEIIC_02318 1.7e-139 yqeM Q Methyltransferase
HCMIEIIC_02319 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCMIEIIC_02320 2.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HCMIEIIC_02321 9.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCMIEIIC_02322 1.2e-46 yhbY J RNA-binding protein
HCMIEIIC_02323 3.4e-216 yqeH S Ribosome biogenesis GTPase YqeH
HCMIEIIC_02324 2.4e-95 yqeG S HAD phosphatase, family IIIA
HCMIEIIC_02325 1.3e-165 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCMIEIIC_02326 1.2e-190 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCMIEIIC_02327 1.8e-121 mhqD S Dienelactone hydrolase family
HCMIEIIC_02328 3.7e-179 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
HCMIEIIC_02329 1e-99 yvdD 3.2.2.10 S Belongs to the LOG family
HCMIEIIC_02330 2.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCMIEIIC_02331 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HCMIEIIC_02332 8.9e-78 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCMIEIIC_02333 2.8e-92 spoVK O ATPase family associated with various cellular activities (AAA)
HCMIEIIC_02334 1.2e-125 spoVK O ATPase family associated with various cellular activities (AAA)
HCMIEIIC_02335 4.3e-12
HCMIEIIC_02336 4.2e-37 yfjR K WYL domain
HCMIEIIC_02337 6.5e-125 S SseB protein N-terminal domain
HCMIEIIC_02338 5.5e-65
HCMIEIIC_02339 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCMIEIIC_02340 1.2e-169 dnaI L Primosomal protein DnaI
HCMIEIIC_02341 2.1e-249 dnaB L replication initiation and membrane attachment
HCMIEIIC_02342 3.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCMIEIIC_02343 6.7e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCMIEIIC_02344 1.5e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCMIEIIC_02345 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCMIEIIC_02346 1.3e-117 ybhL S Inhibitor of apoptosis-promoting Bax1
HCMIEIIC_02347 7.7e-172 S Cell surface protein
HCMIEIIC_02349 2.1e-135 S WxL domain surface cell wall-binding
HCMIEIIC_02350 0.0 N domain, Protein
HCMIEIIC_02351 3.8e-263 K Mga helix-turn-helix domain
HCMIEIIC_02352 1e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HCMIEIIC_02353 2.8e-28 sftA D Belongs to the FtsK SpoIIIE SftA family
HCMIEIIC_02354 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HCMIEIIC_02356 1.2e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCMIEIIC_02357 7.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HCMIEIIC_02359 4.5e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCMIEIIC_02360 1.2e-148 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HCMIEIIC_02362 7.2e-220 ecsB U ABC transporter
HCMIEIIC_02363 4.9e-131 ecsA V ABC transporter, ATP-binding protein
HCMIEIIC_02364 5.5e-74 hit FG histidine triad
HCMIEIIC_02365 4.8e-47 yhaH S YtxH-like protein
HCMIEIIC_02366 2.6e-158 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCMIEIIC_02367 3.1e-181 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCMIEIIC_02368 4.6e-55 yheA S Control of competence regulator ComK, YlbF/YmcA
HCMIEIIC_02369 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HCMIEIIC_02370 3.6e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCMIEIIC_02371 7.6e-74 argR K Regulates arginine biosynthesis genes
HCMIEIIC_02372 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HCMIEIIC_02374 5.9e-67
HCMIEIIC_02375 6.1e-22
HCMIEIIC_02376 1.2e-177 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HCMIEIIC_02377 4.5e-303 glpQ 3.1.4.46 C phosphodiesterase
HCMIEIIC_02378 5.1e-122 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HCMIEIIC_02379 1.5e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCMIEIIC_02380 4.6e-137 yhfI S Metallo-beta-lactamase superfamily
HCMIEIIC_02381 7.6e-91 traP 1.14.99.57, 6.2.1.3 S Antibiotic biosynthesis monooxygenase
HCMIEIIC_02382 0.0 V ABC transporter (permease)
HCMIEIIC_02383 2.6e-138 bceA V ABC transporter
HCMIEIIC_02384 1e-122 K response regulator
HCMIEIIC_02385 1.3e-207 T PhoQ Sensor
HCMIEIIC_02386 3.2e-109 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCMIEIIC_02387 0.0 copB 3.6.3.4 P P-type ATPase
HCMIEIIC_02388 1.6e-76 copR K Copper transport repressor CopY TcrY
HCMIEIIC_02391 3.3e-186
HCMIEIIC_02392 5.3e-147 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
HCMIEIIC_02393 1.2e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HCMIEIIC_02394 3.7e-90 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCMIEIIC_02395 2e-94 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCMIEIIC_02396 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HCMIEIIC_02397 7.1e-62
HCMIEIIC_02398 9.4e-83 6.3.3.2 S ASCH
HCMIEIIC_02399 5.9e-32
HCMIEIIC_02400 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCMIEIIC_02401 7.2e-77 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCMIEIIC_02402 1.7e-84 K Acetyltransferase (GNAT) domain
HCMIEIIC_02403 1.5e-163 2.3.1.128 K Acetyltransferase (GNAT) domain
HCMIEIIC_02404 5.7e-83 K Psort location Cytoplasmic, score
HCMIEIIC_02405 2.2e-11 K Psort location Cytoplasmic, score
HCMIEIIC_02407 4.2e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HCMIEIIC_02408 7.2e-79 yphH S Cupin domain
HCMIEIIC_02409 9.4e-161 K Transcriptional regulator
HCMIEIIC_02410 1.8e-128 S ABC-2 family transporter protein
HCMIEIIC_02411 1.9e-167 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
HCMIEIIC_02412 4e-119 T Transcriptional regulatory protein, C terminal
HCMIEIIC_02413 1.8e-151 T GHKL domain
HCMIEIIC_02414 0.0 oppA E ABC transporter, substratebinding protein
HCMIEIIC_02415 1.7e-156 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HCMIEIIC_02416 2.6e-132 dck 2.7.1.74 F deoxynucleoside kinase
HCMIEIIC_02417 2.7e-137 pnuC H nicotinamide mononucleotide transporter
HCMIEIIC_02418 4.7e-61 IQ NAD dependent epimerase/dehydratase family
HCMIEIIC_02419 4.4e-95 IQ NAD dependent epimerase/dehydratase family
HCMIEIIC_02420 7.3e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCMIEIIC_02421 3e-122 G Phosphoglycerate mutase family
HCMIEIIC_02422 7.3e-150 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HCMIEIIC_02423 2.2e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HCMIEIIC_02424 4.1e-107 yktB S Belongs to the UPF0637 family
HCMIEIIC_02425 1e-72 yueI S Protein of unknown function (DUF1694)
HCMIEIIC_02426 0.0 6.3.2.2, 6.3.2.4 M Mur ligase middle domain protein
HCMIEIIC_02427 3.3e-237 rarA L recombination factor protein RarA
HCMIEIIC_02428 1.7e-39
HCMIEIIC_02429 1.5e-83 usp6 T universal stress protein
HCMIEIIC_02430 4.4e-158 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HCMIEIIC_02431 2.2e-179 S Protein of unknown function (DUF2785)
HCMIEIIC_02432 1.3e-18 yueI S Protein of unknown function (DUF1694)
HCMIEIIC_02433 6.9e-26
HCMIEIIC_02435 6.2e-279 sufB O assembly protein SufB
HCMIEIIC_02436 2.9e-78 nifU C SUF system FeS assembly protein, NifU family
HCMIEIIC_02437 5.8e-222 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCMIEIIC_02438 5.9e-191 sufD O FeS assembly protein SufD
HCMIEIIC_02439 1.9e-141 sufC O FeS assembly ATPase SufC
HCMIEIIC_02440 8.8e-106 metI P ABC transporter permease
HCMIEIIC_02441 2.9e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCMIEIIC_02442 3.8e-148 P Belongs to the nlpA lipoprotein family
HCMIEIIC_02443 1.9e-147 P Belongs to the nlpA lipoprotein family
HCMIEIIC_02444 3.2e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HCMIEIIC_02445 1.1e-47 gcvH E glycine cleavage
HCMIEIIC_02446 7.6e-222 rodA D Belongs to the SEDS family
HCMIEIIC_02447 1.3e-31 S Protein of unknown function (DUF2969)
HCMIEIIC_02448 1.6e-54 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HCMIEIIC_02449 1.9e-25 epuA S DNA-directed RNA polymerase subunit beta
HCMIEIIC_02450 1.5e-43 mbl D Cell shape determining protein MreB Mrl
HCMIEIIC_02451 3.5e-97 mbl D Cell shape determining protein MreB Mrl
HCMIEIIC_02452 6.4e-32 ywzB S Protein of unknown function (DUF1146)
HCMIEIIC_02453 1.7e-12
HCMIEIIC_02454 1.6e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HCMIEIIC_02455 1.2e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCMIEIIC_02456 4.1e-07 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HCMIEIIC_02457 2.7e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCMIEIIC_02458 2.1e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCMIEIIC_02459 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCMIEIIC_02460 4.7e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCMIEIIC_02461 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCMIEIIC_02462 3.9e-125 atpB C it plays a direct role in the translocation of protons across the membrane
HCMIEIIC_02463 1.3e-111 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCMIEIIC_02464 2e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCMIEIIC_02465 1.3e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCMIEIIC_02466 2.6e-152 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCMIEIIC_02467 4.8e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCMIEIIC_02468 6e-111 tdk 2.7.1.21 F thymidine kinase
HCMIEIIC_02469 1.9e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HCMIEIIC_02470 1.9e-189 ampC V Beta-lactamase
HCMIEIIC_02471 2.3e-164 1.13.11.2 S glyoxalase
HCMIEIIC_02472 2.5e-118 S NADPH-dependent FMN reductase
HCMIEIIC_02473 0.0 yfiC V ABC transporter
HCMIEIIC_02474 0.0 ycfI V ABC transporter, ATP-binding protein
HCMIEIIC_02475 5.4e-121 K Bacterial regulatory proteins, tetR family
HCMIEIIC_02476 7.5e-119 G Phosphoglycerate mutase family
HCMIEIIC_02477 8.7e-09
HCMIEIIC_02481 2.2e-284 pipD E Dipeptidase
HCMIEIIC_02482 2.5e-193 yttB EGP Major facilitator Superfamily
HCMIEIIC_02483 1.2e-17
HCMIEIIC_02492 5.8e-85 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
HCMIEIIC_02493 1.4e-172 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HCMIEIIC_02494 2.8e-229 wbbX GT2,GT4 M Glycosyl transferases group 1
HCMIEIIC_02495 3.6e-41 yttA 2.7.13.3 S Pfam Transposase IS66
HCMIEIIC_02496 5.1e-45 F DNA/RNA non-specific endonuclease
HCMIEIIC_02497 3.1e-43 F DNA/RNA non-specific endonuclease
HCMIEIIC_02498 5.6e-46 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HCMIEIIC_02500 7.3e-258 pgi 5.3.1.9 G Belongs to the GPI family
HCMIEIIC_02501 1.9e-150 glcU U sugar transport
HCMIEIIC_02502 1.5e-109 vanZ V VanZ like family
HCMIEIIC_02503 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCMIEIIC_02504 4.7e-129
HCMIEIIC_02505 1.2e-103
HCMIEIIC_02507 4.5e-244 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCMIEIIC_02508 3e-204 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCMIEIIC_02509 7.3e-242 pbuX F xanthine permease
HCMIEIIC_02510 7.9e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCMIEIIC_02511 1.3e-108 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HCMIEIIC_02512 3.2e-81 yvbK 3.1.3.25 K GNAT family
HCMIEIIC_02513 1.2e-25 chpR T PFAM SpoVT AbrB
HCMIEIIC_02514 2.1e-31 cspC K Cold shock protein
HCMIEIIC_02515 1.2e-166 yqjA S Putative aromatic acid exporter C-terminal domain
HCMIEIIC_02516 2.1e-109
HCMIEIIC_02517 2.1e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HCMIEIIC_02518 1.6e-83 S Fic/DOC family
HCMIEIIC_02519 3e-304 S Psort location CytoplasmicMembrane, score
HCMIEIIC_02520 0.0 S Bacterial membrane protein YfhO
HCMIEIIC_02521 5.2e-307 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCMIEIIC_02522 2.2e-287 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCMIEIIC_02523 6.2e-220 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCMIEIIC_02524 2.1e-39 M transferase activity, transferring glycosyl groups
HCMIEIIC_02525 4.7e-56 M Glycosyl transferase family 8
HCMIEIIC_02526 9.1e-119 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HCMIEIIC_02527 1.5e-08 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCMIEIIC_02528 3.8e-21 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HCMIEIIC_02529 2.5e-281 G Phosphodiester glycosidase
HCMIEIIC_02531 6e-288 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
HCMIEIIC_02532 4.5e-205 S Protein of unknown function (DUF917)
HCMIEIIC_02533 3.5e-222 F Permease for cytosine/purines, uracil, thiamine, allantoin
HCMIEIIC_02534 1.3e-116
HCMIEIIC_02535 3.4e-65 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HCMIEIIC_02536 2e-166 L Belongs to the 'phage' integrase family
HCMIEIIC_02537 2.5e-55 3.1.21.3 V Type I restriction modification DNA specificity domain protein
HCMIEIIC_02538 1.9e-215 hsdM 2.1.1.72 V type I restriction-modification system
HCMIEIIC_02539 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HCMIEIIC_02540 7e-212 ykiI
HCMIEIIC_02541 0.0 pip V domain protein
HCMIEIIC_02542 0.0 scrA 2.7.1.211 G phosphotransferase system
HCMIEIIC_02543 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HCMIEIIC_02544 1.5e-175 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HCMIEIIC_02545 9.4e-299 scrB 3.2.1.26 GH32 G invertase
HCMIEIIC_02547 7.8e-160 azoB GM NmrA-like family
HCMIEIIC_02548 5.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HCMIEIIC_02549 2e-143 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HCMIEIIC_02550 7.6e-149 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCMIEIIC_02551 3.6e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HCMIEIIC_02552 1.2e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCMIEIIC_02553 1.1e-43 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCMIEIIC_02554 2e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCMIEIIC_02555 2.8e-126 IQ reductase
HCMIEIIC_02556 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HCMIEIIC_02557 2.4e-173 fabK 1.3.1.9 S Nitronate monooxygenase
HCMIEIIC_02558 4.5e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCMIEIIC_02559 1.8e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCMIEIIC_02560 4.7e-76 marR K Winged helix DNA-binding domain
HCMIEIIC_02561 9e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HCMIEIIC_02562 2.2e-190 I carboxylic ester hydrolase activity
HCMIEIIC_02563 2e-227 bdhA C Iron-containing alcohol dehydrogenase
HCMIEIIC_02564 7.1e-62 P Rhodanese-like domain
HCMIEIIC_02565 5.7e-84 yetL K helix_turn_helix multiple antibiotic resistance protein
HCMIEIIC_02566 3.5e-80 2.7.7.65 T diguanylate cyclase activity
HCMIEIIC_02567 5.3e-202 ydaN S Bacterial cellulose synthase subunit
HCMIEIIC_02568 6.8e-181 ydaM M Glycosyl transferase family group 2
HCMIEIIC_02569 5.8e-81 S Protein conserved in bacteria
HCMIEIIC_02570 8.6e-74
HCMIEIIC_02571 2.1e-80 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HCMIEIIC_02572 5.3e-58 2.7.7.65 T diguanylate cyclase
HCMIEIIC_02573 5.7e-162 nox C NADH oxidase
HCMIEIIC_02574 3.7e-72 yliE T Putative diguanylate phosphodiesterase
HCMIEIIC_02575 4.3e-26
HCMIEIIC_02576 3.7e-67 K MarR family
HCMIEIIC_02577 4e-11 S response to antibiotic
HCMIEIIC_02578 1.2e-159 S Putative esterase
HCMIEIIC_02579 6.4e-183
HCMIEIIC_02580 3.5e-103 rmaB K Transcriptional regulator, MarR family
HCMIEIIC_02581 4.9e-84 F NUDIX domain
HCMIEIIC_02582 3.5e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCMIEIIC_02583 3.4e-29
HCMIEIIC_02584 4.4e-125 S zinc-ribbon domain
HCMIEIIC_02585 1.3e-196 pbpX1 V Beta-lactamase
HCMIEIIC_02586 1.5e-181 K AI-2E family transporter
HCMIEIIC_02587 1.1e-127 srtA 3.4.22.70 M Sortase family
HCMIEIIC_02588 1.5e-65 gtcA S Teichoic acid glycosylation protein
HCMIEIIC_02589 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCMIEIIC_02590 1.6e-168 gbuC E glycine betaine
HCMIEIIC_02591 1.8e-124 proW E glycine betaine
HCMIEIIC_02592 1.9e-220 gbuA 3.6.3.32 E glycine betaine
HCMIEIIC_02593 4.4e-132 sfsA S Belongs to the SfsA family
HCMIEIIC_02594 1.6e-66 usp1 T Universal stress protein family
HCMIEIIC_02595 1.8e-250 yxbA 6.3.1.12 S ATP-grasp enzyme
HCMIEIIC_02596 3.5e-152 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCMIEIIC_02597 1.2e-280 thrC 4.2.3.1 E Threonine synthase
HCMIEIIC_02598 3.7e-229 hom 1.1.1.3 E homoserine dehydrogenase
HCMIEIIC_02599 6.6e-70 yclM 2.7.2.4 E Belongs to the aspartokinase family
HCMIEIIC_02600 2.2e-148 yclM 2.7.2.4 E Belongs to the aspartokinase family
HCMIEIIC_02601 5.8e-166 yqiK S SPFH domain / Band 7 family
HCMIEIIC_02602 5.7e-68
HCMIEIIC_02603 1.5e-154 pfoS S Phosphotransferase system, EIIC
HCMIEIIC_02604 2.6e-153 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCMIEIIC_02605 4.2e-217 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HCMIEIIC_02606 6.2e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
HCMIEIIC_02607 6e-143 S Alpha/beta hydrolase family
HCMIEIIC_02608 2.3e-102 K Bacterial regulatory proteins, tetR family
HCMIEIIC_02609 1.2e-171 XK27_06930 V domain protein
HCMIEIIC_02610 2.1e-171 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCMIEIIC_02611 0.0 asnB 6.3.5.4 E Asparagine synthase
HCMIEIIC_02612 2.2e-08
HCMIEIIC_02613 5.2e-206 S Calcineurin-like phosphoesterase
HCMIEIIC_02614 1.3e-160 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HCMIEIIC_02615 2.8e-174 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCMIEIIC_02616 1.2e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCMIEIIC_02617 5.7e-166 natA S ABC transporter
HCMIEIIC_02618 1.6e-209 ysdA CP ABC-2 family transporter protein
HCMIEIIC_02619 8.1e-64 K helix_turn_helix gluconate operon transcriptional repressor
HCMIEIIC_02620 4.9e-162 CcmA V ABC transporter
HCMIEIIC_02621 5.7e-115 VPA0052 I ABC-2 family transporter protein
HCMIEIIC_02622 5.8e-146 IQ reductase
HCMIEIIC_02623 1.8e-257 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCMIEIIC_02624 0.0 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCMIEIIC_02625 1.7e-159 licT K CAT RNA binding domain
HCMIEIIC_02626 3.2e-284 cydC V ABC transporter transmembrane region
HCMIEIIC_02627 6.1e-310 cydD CO ABC transporter transmembrane region
HCMIEIIC_02628 1.7e-75 ynhH S NusG domain II
HCMIEIIC_02629 2.8e-170 M Peptidoglycan-binding domain 1 protein
HCMIEIIC_02631 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HCMIEIIC_02632 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HCMIEIIC_02633 6.5e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HCMIEIIC_02634 1.8e-278 cydA 1.10.3.14 C ubiquinol oxidase
HCMIEIIC_02635 2e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HCMIEIIC_02636 6.5e-174 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HCMIEIIC_02637 1.7e-37
HCMIEIIC_02638 2.1e-85
HCMIEIIC_02639 2.7e-24
HCMIEIIC_02640 5.2e-162 yicL EG EamA-like transporter family
HCMIEIIC_02641 1.9e-112 tag 3.2.2.20 L glycosylase
HCMIEIIC_02642 3.1e-66 S Psort location Cytoplasmic, score
HCMIEIIC_02643 6e-12
HCMIEIIC_02644 4.8e-131 S Domain of unknown function (DUF4918)
HCMIEIIC_02645 1.8e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCMIEIIC_02646 3.6e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCMIEIIC_02647 1.4e-147 dprA LU DNA protecting protein DprA
HCMIEIIC_02648 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCMIEIIC_02649 3e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HCMIEIIC_02650 1.5e-166 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HCMIEIIC_02651 5.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HCMIEIIC_02652 5e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HCMIEIIC_02653 6.2e-173 lacX 5.1.3.3 G Aldose 1-epimerase
HCMIEIIC_02654 4.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCMIEIIC_02655 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCMIEIIC_02656 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCMIEIIC_02657 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HCMIEIIC_02658 4.3e-171 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCMIEIIC_02659 1.8e-181 K LysR substrate binding domain
HCMIEIIC_02660 9.5e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
HCMIEIIC_02661 2.9e-207 xerS L Belongs to the 'phage' integrase family
HCMIEIIC_02662 0.0 ysaB V FtsX-like permease family
HCMIEIIC_02663 3.8e-134 XK27_05695 V ABC transporter, ATP-binding protein
HCMIEIIC_02664 5.2e-173 T Histidine kinase-like ATPases
HCMIEIIC_02665 4.8e-128 T Transcriptional regulatory protein, C terminal
HCMIEIIC_02666 1.1e-217 EGP Transmembrane secretion effector
HCMIEIIC_02667 7.1e-68 msi198 K Acetyltransferase (GNAT) domain
HCMIEIIC_02668 5.9e-70 K Acetyltransferase (GNAT) domain
HCMIEIIC_02669 2.6e-112 nfnB 1.5.1.34 C Nitroreductase family
HCMIEIIC_02670 3.9e-145 Q Fumarylacetoacetate (FAA) hydrolase family
HCMIEIIC_02671 3.1e-206 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HCMIEIIC_02672 6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HCMIEIIC_02673 2.1e-57 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HCMIEIIC_02674 3.2e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HCMIEIIC_02675 4.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HCMIEIIC_02676 1.5e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HCMIEIIC_02677 2.4e-104 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HCMIEIIC_02678 3.5e-225 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HCMIEIIC_02679 5.6e-99 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HCMIEIIC_02680 9.2e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HCMIEIIC_02681 8.5e-204 hisC 2.6.1.9 E Cys/Met metabolism PLP-dependent enzyme
HCMIEIIC_02682 1.5e-100 3.6.1.13 L Belongs to the Nudix hydrolase family
HCMIEIIC_02683 3.2e-161 degV S EDD domain protein, DegV family
HCMIEIIC_02684 8.1e-09
HCMIEIIC_02685 0.0 FbpA K Fibronectin-binding protein
HCMIEIIC_02686 6.2e-51 S MazG-like family
HCMIEIIC_02687 7e-193 pfoS S Phosphotransferase system, EIIC
HCMIEIIC_02688 2.9e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCMIEIIC_02689 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCMIEIIC_02690 2.1e-152 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCMIEIIC_02691 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HCMIEIIC_02692 1e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCMIEIIC_02693 2.5e-239 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCMIEIIC_02694 2.8e-179 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HCMIEIIC_02695 2.6e-236 pyrP F Permease
HCMIEIIC_02696 1.7e-96 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCMIEIIC_02697 5e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCMIEIIC_02698 9.2e-82 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCMIEIIC_02699 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HCMIEIIC_02700 2.4e-63 S Family of unknown function (DUF5322)
HCMIEIIC_02701 1.1e-68 rnhA 3.1.26.4 L Ribonuclease HI
HCMIEIIC_02702 1.5e-109 XK27_02070 S Nitroreductase family
HCMIEIIC_02703 1.8e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCMIEIIC_02704 9.7e-55
HCMIEIIC_02706 1.6e-271 K Mga helix-turn-helix domain
HCMIEIIC_02707 4.5e-38 nrdH O Glutaredoxin
HCMIEIIC_02708 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCMIEIIC_02709 1.2e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCMIEIIC_02711 1.2e-163 K Transcriptional regulator
HCMIEIIC_02712 0.0 pepO 3.4.24.71 O Peptidase family M13
HCMIEIIC_02713 1.6e-193 lplA 6.3.1.20 H Lipoate-protein ligase
HCMIEIIC_02714 9.8e-28
HCMIEIIC_02715 7.8e-174 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HCMIEIIC_02716 3.7e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HCMIEIIC_02718 1.8e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCMIEIIC_02719 1.9e-106 ypsA S Belongs to the UPF0398 family
HCMIEIIC_02720 1.5e-120 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCMIEIIC_02721 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HCMIEIIC_02722 1.2e-85 comEB 3.5.4.12 F ComE operon protein 2
HCMIEIIC_02723 2.4e-113 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCMIEIIC_02724 2.4e-110 dnaD L DnaD domain protein
HCMIEIIC_02725 3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HCMIEIIC_02726 2.4e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HCMIEIIC_02727 2.1e-85 ypmB S Protein conserved in bacteria
HCMIEIIC_02728 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HCMIEIIC_02729 2.8e-113 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HCMIEIIC_02730 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HCMIEIIC_02731 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HCMIEIIC_02732 4.6e-166 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HCMIEIIC_02733 2.1e-177 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HCMIEIIC_02734 3.6e-196 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HCMIEIIC_02735 1.4e-261 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HCMIEIIC_02736 4.7e-174
HCMIEIIC_02737 5.9e-140
HCMIEIIC_02738 2.8e-60 yitW S Iron-sulfur cluster assembly protein
HCMIEIIC_02739 7.3e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HCMIEIIC_02740 1e-271 V (ABC) transporter
HCMIEIIC_02741 1e-309 V ABC transporter transmembrane region
HCMIEIIC_02742 1.8e-147 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCMIEIIC_02743 1.7e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
HCMIEIIC_02744 4.4e-196 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCMIEIIC_02745 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCMIEIIC_02746 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HCMIEIIC_02747 1.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HCMIEIIC_02748 2e-94 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
HCMIEIIC_02750 1.8e-49 V ATPases associated with a variety of cellular activities
HCMIEIIC_02751 4.3e-08 L Transposase and inactivated derivatives, IS30 family
HCMIEIIC_02752 6.7e-85 S Short repeat of unknown function (DUF308)
HCMIEIIC_02753 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCMIEIIC_02754 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCMIEIIC_02755 5.5e-118 yfbR S HD containing hydrolase-like enzyme
HCMIEIIC_02756 1.2e-147 V FtsX-like permease family
HCMIEIIC_02757 1.1e-87 V FtsX-like permease family
HCMIEIIC_02758 1.2e-91 V ABC transporter
HCMIEIIC_02759 8.9e-115 T His Kinase A (phosphoacceptor) domain
HCMIEIIC_02760 6.8e-84 T Transcriptional regulatory protein, C terminal
HCMIEIIC_02761 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HCMIEIIC_02762 3.3e-180 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCMIEIIC_02763 2.9e-193 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HCMIEIIC_02764 3.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCMIEIIC_02765 2.8e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCMIEIIC_02766 1.3e-46 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HCMIEIIC_02767 7.1e-32
HCMIEIIC_02768 4.8e-210 yvlB S Putative adhesin
HCMIEIIC_02769 3e-119 phoU P Plays a role in the regulation of phosphate uptake
HCMIEIIC_02770 7.1e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCMIEIIC_02771 1.2e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCMIEIIC_02772 1.1e-156 pstA P Phosphate transport system permease protein PstA
HCMIEIIC_02773 3.4e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HCMIEIIC_02774 4.4e-155 pstS P Phosphate
HCMIEIIC_02775 1.1e-306 phoR 2.7.13.3 T Histidine kinase
HCMIEIIC_02776 5.2e-130 K response regulator
HCMIEIIC_02777 1.6e-194 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HCMIEIIC_02778 1.8e-159 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HCMIEIIC_02779 1.9e-124 ftsE D ABC transporter
HCMIEIIC_02780 8.9e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCMIEIIC_02781 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCMIEIIC_02782 5.4e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCMIEIIC_02783 1.3e-90 comFC S Competence protein
HCMIEIIC_02784 4.1e-234 comFA L Helicase C-terminal domain protein
HCMIEIIC_02785 9.5e-118 yvyE 3.4.13.9 S YigZ family
HCMIEIIC_02786 1.5e-202 rny S Endoribonuclease that initiates mRNA decay
HCMIEIIC_02787 1.1e-19 rny S Endoribonuclease that initiates mRNA decay
HCMIEIIC_02788 3.6e-21
HCMIEIIC_02789 1.2e-09
HCMIEIIC_02790 1.3e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCMIEIIC_02791 1.4e-226 cinA 3.5.1.42 S Belongs to the CinA family
HCMIEIIC_02792 1.6e-103 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCMIEIIC_02793 2e-116 ymfM S Helix-turn-helix domain
HCMIEIIC_02794 1.1e-127 IQ Enoyl-(Acyl carrier protein) reductase
HCMIEIIC_02795 2.2e-243 ymfH S Peptidase M16
HCMIEIIC_02796 6.1e-230 ymfF S Peptidase M16 inactive domain protein
HCMIEIIC_02797 3e-264 ftsK D Belongs to the FtsK SpoIIIE SftA family
HCMIEIIC_02798 4.1e-12 ftsK D Belongs to the FtsK SpoIIIE SftA family
HCMIEIIC_02799 5.4e-71 WQ51_03320 S Protein of unknown function (DUF1149)
HCMIEIIC_02800 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCMIEIIC_02801 2.4e-153 rrmA 2.1.1.187 H Methyltransferase
HCMIEIIC_02802 5.7e-172 corA P CorA-like Mg2+ transporter protein
HCMIEIIC_02803 7.4e-191 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCMIEIIC_02804 2.9e-38 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCMIEIIC_02805 1.2e-61 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HCMIEIIC_02806 2.3e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HCMIEIIC_02807 3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HCMIEIIC_02808 1.3e-111 cutC P Participates in the control of copper homeostasis
HCMIEIIC_02809 1.2e-202 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCMIEIIC_02810 7.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HCMIEIIC_02811 1.4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCMIEIIC_02812 2.7e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
HCMIEIIC_02813 1.2e-103 yjbK S CYTH
HCMIEIIC_02814 1.5e-115 yjbH Q Thioredoxin
HCMIEIIC_02815 1.1e-211 coiA 3.6.4.12 S Competence protein
HCMIEIIC_02816 1.3e-243 XK27_08635 S UPF0210 protein
HCMIEIIC_02817 1.5e-37 gcvR T Belongs to the UPF0237 family
HCMIEIIC_02818 2.9e-222 cpdA S Calcineurin-like phosphoesterase
HCMIEIIC_02819 6.7e-226 malY 4.4.1.8 E Aminotransferase, class I
HCMIEIIC_02820 4.8e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HCMIEIIC_02822 2.6e-95 FNV0100 F NUDIX domain
HCMIEIIC_02823 8.9e-137 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCMIEIIC_02824 3.3e-35 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HCMIEIIC_02825 3.4e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCMIEIIC_02826 7.8e-278 ytgP S Polysaccharide biosynthesis protein
HCMIEIIC_02827 5.7e-11
HCMIEIIC_02828 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCMIEIIC_02829 6.7e-119 3.6.1.27 I Acid phosphatase homologues
HCMIEIIC_02830 2.1e-113 S Domain of unknown function (DUF4811)
HCMIEIIC_02831 4.1e-37 lmrB EGP Major facilitator Superfamily
HCMIEIIC_02832 3.3e-217 lmrB EGP Major facilitator Superfamily
HCMIEIIC_02833 1.3e-81 merR K MerR HTH family regulatory protein
HCMIEIIC_02834 2.4e-273 emrY EGP Major facilitator Superfamily
HCMIEIIC_02835 1e-207 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCMIEIIC_02836 2.6e-99

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)