ORF_ID e_value Gene_name EC_number CAZy COGs Description
HHCIPGHA_00001 1.6e-180 lacR K Transcriptional regulator
HHCIPGHA_00002 1.6e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHCIPGHA_00003 7e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HHCIPGHA_00004 3.3e-191 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HHCIPGHA_00005 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HHCIPGHA_00006 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHCIPGHA_00007 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HHCIPGHA_00008 4e-90 S Short repeat of unknown function (DUF308)
HHCIPGHA_00009 6e-160 rapZ S Displays ATPase and GTPase activities
HHCIPGHA_00010 4.4e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HHCIPGHA_00011 1.8e-170 whiA K May be required for sporulation
HHCIPGHA_00012 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHCIPGHA_00013 2.2e-276 ycaM E amino acid
HHCIPGHA_00015 5.2e-187 cggR K Putative sugar-binding domain
HHCIPGHA_00016 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHCIPGHA_00017 6e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HHCIPGHA_00018 4.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHCIPGHA_00019 3.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHCIPGHA_00020 2.5e-28 secG U Preprotein translocase
HHCIPGHA_00021 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHCIPGHA_00022 2.3e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HHCIPGHA_00023 8.6e-107 3.2.2.20 K acetyltransferase
HHCIPGHA_00025 1.9e-90
HHCIPGHA_00026 2.9e-93
HHCIPGHA_00027 8.8e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
HHCIPGHA_00028 6.9e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHCIPGHA_00029 3.5e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HHCIPGHA_00030 6.5e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HHCIPGHA_00031 1.6e-99 dnaQ 2.7.7.7 L DNA polymerase III
HHCIPGHA_00032 7.6e-166 murB 1.3.1.98 M Cell wall formation
HHCIPGHA_00033 1.3e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHCIPGHA_00034 3e-129 potB P ABC transporter permease
HHCIPGHA_00035 2.2e-137 potC P ABC transporter permease
HHCIPGHA_00036 4.3e-208 potD P ABC transporter
HHCIPGHA_00037 3.4e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHCIPGHA_00038 4e-173 ybbR S YbbR-like protein
HHCIPGHA_00039 5.9e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHCIPGHA_00040 2.1e-146 S Sucrose-6F-phosphate phosphohydrolase
HHCIPGHA_00041 1.9e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHCIPGHA_00042 1.6e-61 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHCIPGHA_00043 6.4e-176 S Putative adhesin
HHCIPGHA_00044 1.5e-113
HHCIPGHA_00045 9.4e-149 yisY 1.11.1.10 S Alpha/beta hydrolase family
HHCIPGHA_00046 8.6e-162 znuA P Belongs to the bacterial solute-binding protein 9 family
HHCIPGHA_00047 1.3e-213 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHCIPGHA_00048 9.5e-97 S VanZ like family
HHCIPGHA_00049 9.9e-132 yebC K Transcriptional regulatory protein
HHCIPGHA_00050 3.3e-192 comGA NU Type II IV secretion system protein
HHCIPGHA_00051 1.2e-175 comGB NU type II secretion system
HHCIPGHA_00052 1.4e-36 comGC U Required for transformation and DNA binding
HHCIPGHA_00053 4.8e-67
HHCIPGHA_00055 2.1e-85 comGF U Putative Competence protein ComGF
HHCIPGHA_00056 1.6e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
HHCIPGHA_00057 2.1e-224 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHCIPGHA_00059 2.9e-90 sip L Belongs to the 'phage' integrase family
HHCIPGHA_00062 6.7e-74
HHCIPGHA_00063 7e-71 E Zn peptidase
HHCIPGHA_00064 5.1e-27 ps115 K Helix-turn-helix XRE-family like proteins
HHCIPGHA_00066 1e-09
HHCIPGHA_00067 7.2e-13
HHCIPGHA_00068 1.2e-42 S Siphovirus Gp157
HHCIPGHA_00070 6.2e-206 res L Helicase C-terminal domain protein
HHCIPGHA_00073 1.8e-112 L AAA domain
HHCIPGHA_00074 4.7e-36
HHCIPGHA_00075 3.7e-103 S Bifunctional DNA primase/polymerase, N-terminal
HHCIPGHA_00076 2e-167 S Virulence-associated protein E
HHCIPGHA_00077 2.2e-12 S sequence-specific DNA binding
HHCIPGHA_00083 6.8e-51 S VRR_NUC
HHCIPGHA_00084 3e-54 arpU S Phage transcriptional regulator, ArpU family
HHCIPGHA_00087 1.7e-54 L Terminase small subunit
HHCIPGHA_00088 2.8e-227 S Phage terminase, large subunit
HHCIPGHA_00089 2.5e-232 S Phage portal protein, SPP1 Gp6-like
HHCIPGHA_00090 6.1e-124 S Phage Mu protein F like protein
HHCIPGHA_00092 1.2e-68 S Domain of unknown function (DUF4355)
HHCIPGHA_00093 5.8e-169
HHCIPGHA_00094 3.9e-57 S Phage gp6-like head-tail connector protein
HHCIPGHA_00095 3.7e-27
HHCIPGHA_00096 6.2e-26 S Bacteriophage HK97-gp10, putative tail-component
HHCIPGHA_00097 5.4e-44 S Protein of unknown function (DUF3168)
HHCIPGHA_00098 1.5e-80 S Phage tail tube protein
HHCIPGHA_00099 1.2e-32 S Phage tail assembly chaperone protein, TAC
HHCIPGHA_00100 4.5e-16
HHCIPGHA_00101 1.7e-176 Z012_10445 D Phage tail tape measure protein
HHCIPGHA_00102 1.4e-126 S phage tail
HHCIPGHA_00103 0.0 M Prophage endopeptidase tail
HHCIPGHA_00104 1.6e-48
HHCIPGHA_00105 2.9e-227 S Calcineurin-like phosphoesterase
HHCIPGHA_00106 9.3e-07
HHCIPGHA_00108 2.1e-07
HHCIPGHA_00109 1.6e-59 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HHCIPGHA_00110 1.3e-165 S N-acetylmuramoyl-L-alanine amidase activity
HHCIPGHA_00111 2.7e-220 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HHCIPGHA_00112 1.4e-58 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HHCIPGHA_00113 2.7e-75 M Protein of unknown function (DUF3737)
HHCIPGHA_00114 2.5e-193 patB 4.4.1.8 E Aminotransferase, class I
HHCIPGHA_00115 9.5e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
HHCIPGHA_00116 4.6e-67 S SdpI/YhfL protein family
HHCIPGHA_00117 9.9e-129 K Transcriptional regulatory protein, C terminal
HHCIPGHA_00118 1.1e-267 T PhoQ Sensor
HHCIPGHA_00119 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HHCIPGHA_00120 1.4e-107 vanZ V VanZ like family
HHCIPGHA_00121 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
HHCIPGHA_00122 7.4e-216 EGP Major facilitator Superfamily
HHCIPGHA_00123 5e-70
HHCIPGHA_00126 1.9e-189 ampC V Beta-lactamase
HHCIPGHA_00127 1.4e-261 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HHCIPGHA_00128 1.6e-111 tdk 2.7.1.21 F thymidine kinase
HHCIPGHA_00129 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHCIPGHA_00130 8.6e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHCIPGHA_00131 1.7e-187 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHCIPGHA_00132 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHCIPGHA_00133 1.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
HHCIPGHA_00134 1.2e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHCIPGHA_00135 2.6e-43 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHCIPGHA_00136 4.9e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHCIPGHA_00137 6.7e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHCIPGHA_00138 7e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHCIPGHA_00139 5.7e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHCIPGHA_00140 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HHCIPGHA_00141 4.5e-30 ywzB S Protein of unknown function (DUF1146)
HHCIPGHA_00142 2.2e-179 mbl D Cell shape determining protein MreB Mrl
HHCIPGHA_00143 3.3e-15 S DNA-directed RNA polymerase subunit beta
HHCIPGHA_00144 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HHCIPGHA_00145 1.3e-34 S Protein of unknown function (DUF2969)
HHCIPGHA_00146 4.7e-224 rodA D Belongs to the SEDS family
HHCIPGHA_00147 5.2e-81 usp6 T universal stress protein
HHCIPGHA_00149 2e-236 rarA L recombination factor protein RarA
HHCIPGHA_00150 1.7e-81 yueI S Protein of unknown function (DUF1694)
HHCIPGHA_00151 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHCIPGHA_00153 2.5e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HHCIPGHA_00154 1.9e-214 iscS2 2.8.1.7 E Aminotransferase class V
HHCIPGHA_00155 9.4e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHCIPGHA_00156 8.9e-122 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHCIPGHA_00157 1.1e-206 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HHCIPGHA_00158 0.0 3.6.3.8 P P-type ATPase
HHCIPGHA_00159 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHCIPGHA_00160 2.1e-230 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HHCIPGHA_00161 1.7e-122 S Haloacid dehalogenase-like hydrolase
HHCIPGHA_00162 1e-110 radC L DNA repair protein
HHCIPGHA_00163 8.4e-166 mreB D cell shape determining protein MreB
HHCIPGHA_00164 1e-143 mreC M Involved in formation and maintenance of cell shape
HHCIPGHA_00165 1.9e-92 mreD
HHCIPGHA_00166 3.6e-13 S Protein of unknown function (DUF4044)
HHCIPGHA_00167 3.9e-51 S Protein of unknown function (DUF3397)
HHCIPGHA_00168 4.1e-77 mraZ K Belongs to the MraZ family
HHCIPGHA_00169 1.1e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHCIPGHA_00170 6.3e-55 ftsL D Cell division protein FtsL
HHCIPGHA_00171 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HHCIPGHA_00172 1.6e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHCIPGHA_00173 2.8e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHCIPGHA_00174 4e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHCIPGHA_00175 1.4e-150 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HHCIPGHA_00176 2.8e-236 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HHCIPGHA_00177 5.4e-232 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHCIPGHA_00178 3.6e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HHCIPGHA_00179 2e-27 yggT S YGGT family
HHCIPGHA_00180 1.6e-143 ylmH S S4 domain protein
HHCIPGHA_00181 1.5e-117 gpsB D DivIVA domain protein
HHCIPGHA_00182 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHCIPGHA_00183 2e-32 cspA K 'Cold-shock' DNA-binding domain
HHCIPGHA_00184 9.7e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HHCIPGHA_00185 2.4e-09
HHCIPGHA_00186 1.6e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHCIPGHA_00187 3.3e-214 iscS 2.8.1.7 E Aminotransferase class V
HHCIPGHA_00188 1.6e-57 XK27_04120 S Putative amino acid metabolism
HHCIPGHA_00189 6.7e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHCIPGHA_00190 2.2e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HHCIPGHA_00191 1.2e-112 S Repeat protein
HHCIPGHA_00192 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHCIPGHA_00193 1.2e-174 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HHCIPGHA_00194 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHCIPGHA_00195 3e-34 ykzG S Belongs to the UPF0356 family
HHCIPGHA_00196 2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHCIPGHA_00197 0.0 typA T GTP-binding protein TypA
HHCIPGHA_00198 5.9e-211 ftsW D Belongs to the SEDS family
HHCIPGHA_00199 6.1e-52 ylbG S UPF0298 protein
HHCIPGHA_00200 2.1e-94 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HHCIPGHA_00201 5.6e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHCIPGHA_00202 8.4e-182 ylbL T Belongs to the peptidase S16 family
HHCIPGHA_00204 0.0 comEC S Competence protein ComEC
HHCIPGHA_00205 1.5e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
HHCIPGHA_00206 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HHCIPGHA_00207 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHCIPGHA_00208 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHCIPGHA_00209 1.1e-158
HHCIPGHA_00210 5.6e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HHCIPGHA_00211 9.5e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHCIPGHA_00212 5.9e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHCIPGHA_00213 1.2e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
HHCIPGHA_00214 9.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHCIPGHA_00215 4e-79
HHCIPGHA_00216 1.5e-65 S Domain of unknown function (DUF4767)
HHCIPGHA_00217 4.4e-220
HHCIPGHA_00218 8.7e-119 frnE Q DSBA-like thioredoxin domain
HHCIPGHA_00219 5.5e-158
HHCIPGHA_00220 1.6e-74 K DNA-templated transcription, initiation
HHCIPGHA_00222 1.3e-151 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HHCIPGHA_00223 1.9e-134 epsB M biosynthesis protein
HHCIPGHA_00224 4.2e-125 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HHCIPGHA_00225 1.5e-143 ywqE 3.1.3.48 GM PHP domain protein
HHCIPGHA_00226 1.7e-119 rfbP M Bacterial sugar transferase
HHCIPGHA_00227 6.8e-83 cpsF M Oligosaccharide biosynthesis protein Alg14 like
HHCIPGHA_00228 7.1e-81 pssE S Glycosyltransferase family 28 C-terminal domain
HHCIPGHA_00229 2.1e-126 M Glycosyltransferase sugar-binding region containing DXD motif
HHCIPGHA_00230 2e-126 M Glycosyl transferase family 2
HHCIPGHA_00231 1.3e-100 2.7.8.12 GT2 S glycosyl transferase family 2
HHCIPGHA_00232 3.1e-131 M Glycosyl transferase family 2
HHCIPGHA_00233 3.8e-204 glf 5.4.99.9 M UDP-galactopyranose mutase
HHCIPGHA_00234 2.1e-91
HHCIPGHA_00235 1.4e-230 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HHCIPGHA_00236 1.9e-149 S Acyltransferase family
HHCIPGHA_00237 6.3e-213 K Psort location Cytoplasmic, score
HHCIPGHA_00239 1.8e-62 L Reverse transcriptase (RNA-dependent DNA polymerase)
HHCIPGHA_00240 1.2e-15
HHCIPGHA_00241 7.4e-89 L COG3547 Transposase and inactivated derivatives
HHCIPGHA_00242 1.1e-54
HHCIPGHA_00244 1e-130 V Abi-like protein
HHCIPGHA_00245 2.1e-199 KQ helix_turn_helix, mercury resistance
HHCIPGHA_00246 1.8e-208 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HHCIPGHA_00247 4.5e-163 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HHCIPGHA_00248 1.3e-116 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HHCIPGHA_00249 7.7e-188 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HHCIPGHA_00250 2.2e-72 V Abi-like protein
HHCIPGHA_00251 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HHCIPGHA_00252 2.1e-147 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHCIPGHA_00253 3.2e-42 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHCIPGHA_00254 4.4e-78 S CRISPR-associated protein (Cas_Csn2)
HHCIPGHA_00255 8.6e-37 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HHCIPGHA_00256 2.1e-126 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHCIPGHA_00257 5.6e-27 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HHCIPGHA_00258 1.4e-241 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHCIPGHA_00259 1.5e-107 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
HHCIPGHA_00260 7.6e-76 S HIRAN
HHCIPGHA_00262 8.8e-162 htpX O Peptidase family M48
HHCIPGHA_00263 1.3e-30
HHCIPGHA_00264 2.3e-223 patA 2.6.1.1 E Aminotransferase
HHCIPGHA_00265 1.5e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HHCIPGHA_00266 1.9e-138 E GDSL-like Lipase/Acylhydrolase family
HHCIPGHA_00267 1.6e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHCIPGHA_00268 1.3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHCIPGHA_00269 1e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HHCIPGHA_00270 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HHCIPGHA_00271 9.2e-40 yqeY S YqeY-like protein
HHCIPGHA_00272 4.7e-174 phoH T phosphate starvation-inducible protein PhoH
HHCIPGHA_00273 1.5e-89 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHCIPGHA_00274 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHCIPGHA_00275 2.8e-137 recO L Involved in DNA repair and RecF pathway recombination
HHCIPGHA_00276 6.1e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HHCIPGHA_00277 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HHCIPGHA_00278 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHCIPGHA_00279 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHCIPGHA_00280 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_00281 1.5e-164 3.5.2.6 V Beta-lactamase enzyme family
HHCIPGHA_00282 2e-166 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HHCIPGHA_00283 1.4e-77 yjcF S Acetyltransferase (GNAT) domain
HHCIPGHA_00284 1.9e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HHCIPGHA_00285 2.2e-76 yybA 2.3.1.57 K Transcriptional regulator
HHCIPGHA_00286 5.6e-43 ypaA S Protein of unknown function (DUF1304)
HHCIPGHA_00287 3e-240 G Bacterial extracellular solute-binding protein
HHCIPGHA_00288 5.6e-255 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HHCIPGHA_00289 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
HHCIPGHA_00290 2.3e-156 gtsB P ABC-type sugar transport systems, permease components
HHCIPGHA_00291 6e-202 malK P ATPases associated with a variety of cellular activities
HHCIPGHA_00292 4.1e-283 pipD E Dipeptidase
HHCIPGHA_00293 4.8e-130 endA F DNA RNA non-specific endonuclease
HHCIPGHA_00294 5e-148 dkg S reductase
HHCIPGHA_00295 1.2e-200 ltrA S Bacterial low temperature requirement A protein (LtrA)
HHCIPGHA_00296 5.6e-183 dnaQ 2.7.7.7 L EXOIII
HHCIPGHA_00297 7.5e-141 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HHCIPGHA_00298 2e-112 yviA S Protein of unknown function (DUF421)
HHCIPGHA_00299 2.2e-73 S Protein of unknown function (DUF3290)
HHCIPGHA_00300 1.1e-242 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HHCIPGHA_00301 3e-93 S PAS domain
HHCIPGHA_00302 6.3e-145 pnuC H nicotinamide mononucleotide transporter
HHCIPGHA_00303 0.0 M domain protein
HHCIPGHA_00304 2e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HHCIPGHA_00305 1.5e-160 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHCIPGHA_00306 8.7e-128 S PAS domain
HHCIPGHA_00307 6.7e-238 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHCIPGHA_00308 4.1e-214 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HHCIPGHA_00309 8e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHCIPGHA_00310 5.5e-223 dnaX 2.4.99.16, 2.7.7.7 GH13 M domain protein
HHCIPGHA_00311 0.0 dnaX 2.4.99.16, 2.7.7.7 GH13 M domain protein
HHCIPGHA_00312 8.5e-69
HHCIPGHA_00313 0.0 uvrA3 L excinuclease ABC, A subunit
HHCIPGHA_00314 0.0 oppA E ABC transporter substrate-binding protein
HHCIPGHA_00315 3e-100 S PFAM Archaeal ATPase
HHCIPGHA_00316 2.3e-157 EG EamA-like transporter family
HHCIPGHA_00317 2e-193 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHCIPGHA_00318 6.8e-76 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHCIPGHA_00319 0.0 bglP 2.7.1.211 G phosphotransferase system
HHCIPGHA_00320 2.1e-149 licT K CAT RNA binding domain
HHCIPGHA_00321 0.0 fhaB M Rib/alpha-like repeat
HHCIPGHA_00322 8.8e-12 fhaB M Rib/alpha-like repeat
HHCIPGHA_00323 9.8e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHCIPGHA_00324 6.7e-164 coaA 2.7.1.33 F Pantothenic acid kinase
HHCIPGHA_00325 3.4e-103 E GDSL-like Lipase/Acylhydrolase
HHCIPGHA_00326 1.1e-242 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHCIPGHA_00327 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
HHCIPGHA_00328 2.3e-122 K Helix-turn-helix domain, rpiR family
HHCIPGHA_00329 5.3e-130 yvpB S Peptidase_C39 like family
HHCIPGHA_00330 0.0 helD 3.6.4.12 L DNA helicase
HHCIPGHA_00331 2.5e-115 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HHCIPGHA_00333 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
HHCIPGHA_00334 9.5e-199 UW LPXTG-motif cell wall anchor domain protein
HHCIPGHA_00335 4.2e-228 yttB EGP Major facilitator Superfamily
HHCIPGHA_00336 1.6e-185 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HHCIPGHA_00337 6.6e-14 D nuclear chromosome segregation
HHCIPGHA_00338 5e-143 D nuclear chromosome segregation
HHCIPGHA_00339 3.8e-134 rpl K Helix-turn-helix domain, rpiR family
HHCIPGHA_00340 1.4e-162 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
HHCIPGHA_00341 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHCIPGHA_00342 0.0 pepO 3.4.24.71 O Peptidase family M13
HHCIPGHA_00343 3.4e-201 P ABC transporter
HHCIPGHA_00344 6.4e-221 V ABC-type multidrug transport system, ATPase and permease components
HHCIPGHA_00345 7.5e-308 S Bacterial membrane protein, YfhO
HHCIPGHA_00346 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HHCIPGHA_00347 0.0 kup P Transport of potassium into the cell
HHCIPGHA_00348 0.0 kup P Transport of potassium into the cell
HHCIPGHA_00349 1.7e-72
HHCIPGHA_00350 5.2e-102
HHCIPGHA_00351 1.9e-27
HHCIPGHA_00352 1.4e-34 S Protein of unknown function (DUF2922)
HHCIPGHA_00353 3.3e-256 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHCIPGHA_00354 2.1e-248 lysA2 M Glycosyl hydrolases family 25
HHCIPGHA_00355 4.1e-66 lysA2 M Glycosyl hydrolases family 25
HHCIPGHA_00356 1.1e-144 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
HHCIPGHA_00357 0.0 yjbQ P TrkA C-terminal domain protein
HHCIPGHA_00358 3.9e-176 S Oxidoreductase family, NAD-binding Rossmann fold
HHCIPGHA_00359 2.2e-129
HHCIPGHA_00360 2.9e-148
HHCIPGHA_00361 4.2e-74 S PAS domain
HHCIPGHA_00362 3.8e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHCIPGHA_00363 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHCIPGHA_00364 3.2e-69 2.4.1.83 GT2 S GtrA-like protein
HHCIPGHA_00365 8e-179 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HHCIPGHA_00366 3.1e-114
HHCIPGHA_00367 7.8e-152 glcU U sugar transport
HHCIPGHA_00368 9e-172 yqhA G Aldose 1-epimerase
HHCIPGHA_00369 5.6e-195 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HHCIPGHA_00370 8.1e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHCIPGHA_00371 0.0 XK27_08315 M Sulfatase
HHCIPGHA_00372 7.7e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHCIPGHA_00374 1.7e-222 lacE-1 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HHCIPGHA_00375 1e-71 K CAT RNA binding domain
HHCIPGHA_00376 8e-39 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HHCIPGHA_00377 2.7e-226 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HHCIPGHA_00378 4e-110 pepC 3.4.22.40 E aminopeptidase
HHCIPGHA_00379 3.3e-129 pepC 3.4.22.40 E aminopeptidase
HHCIPGHA_00380 4.5e-120 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HHCIPGHA_00381 1.4e-41 ps301 K sequence-specific DNA binding
HHCIPGHA_00382 5.1e-256 pepC 3.4.22.40 E aminopeptidase
HHCIPGHA_00383 7.7e-43
HHCIPGHA_00384 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHCIPGHA_00385 3.3e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HHCIPGHA_00386 3.4e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHCIPGHA_00387 5.4e-81
HHCIPGHA_00388 1.2e-247 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHCIPGHA_00389 3.9e-84 yydK K UTRA
HHCIPGHA_00390 1e-24 yydK K UTRA
HHCIPGHA_00391 3.9e-31 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_00393 1.3e-100 S response to antibiotic
HHCIPGHA_00394 2.1e-26 acfD M Membrane
HHCIPGHA_00396 7.3e-231 sptS 2.7.13.3 T Histidine kinase
HHCIPGHA_00397 3.4e-115 K response regulator
HHCIPGHA_00398 6.6e-113 2.7.6.5 T Region found in RelA / SpoT proteins
HHCIPGHA_00399 5.3e-121 ltrA S Bacterial low temperature requirement A protein (LtrA)
HHCIPGHA_00400 3.1e-66 O OsmC-like protein
HHCIPGHA_00401 1.7e-287 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HHCIPGHA_00402 2.8e-179 E ABC transporter, ATP-binding protein
HHCIPGHA_00403 1e-148 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHCIPGHA_00404 3.3e-138 2.7.7.7, 3.4.21.110 D Leucine-rich repeat (LRR) protein
HHCIPGHA_00405 1.6e-27 2.7.7.7, 3.4.21.110 D Leucine-rich repeat (LRR) protein
HHCIPGHA_00407 2.3e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HHCIPGHA_00408 2.7e-163 yihY S Belongs to the UPF0761 family
HHCIPGHA_00409 6.7e-161 map 3.4.11.18 E Methionine Aminopeptidase
HHCIPGHA_00410 4.7e-76 fld C Flavodoxin
HHCIPGHA_00411 4.4e-86 gtcA S Teichoic acid glycosylation protein
HHCIPGHA_00412 2.9e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HHCIPGHA_00415 1.1e-248 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHCIPGHA_00416 2.7e-206 yfmL 3.6.4.13 L DEAD DEAH box helicase
HHCIPGHA_00417 3.4e-137 M Glycosyl hydrolases family 25
HHCIPGHA_00418 5.5e-234 potE E amino acid
HHCIPGHA_00419 2.8e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HHCIPGHA_00420 8.9e-251 yhdP S Transporter associated domain
HHCIPGHA_00421 1e-130
HHCIPGHA_00422 3.3e-118 C nitroreductase
HHCIPGHA_00423 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HHCIPGHA_00424 3.5e-135 glcR K DeoR C terminal sensor domain
HHCIPGHA_00425 2.6e-52 S Enterocin A Immunity
HHCIPGHA_00426 2e-132 gntR K UbiC transcription regulator-associated domain protein
HHCIPGHA_00427 3.6e-171 rihB 3.2.2.1 F Nucleoside
HHCIPGHA_00428 4.1e-127 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HHCIPGHA_00429 6.8e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHCIPGHA_00431 4.9e-84 dps P Belongs to the Dps family
HHCIPGHA_00432 7.5e-283 S C4-dicarboxylate anaerobic carrier
HHCIPGHA_00433 2.6e-118 phoU P Plays a role in the regulation of phosphate uptake
HHCIPGHA_00434 2.7e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHCIPGHA_00435 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHCIPGHA_00436 5.4e-156 pstA P Phosphate transport system permease protein PstA
HHCIPGHA_00437 8e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HHCIPGHA_00438 3e-159 pstS P Phosphate
HHCIPGHA_00439 1.7e-96 K Acetyltransferase (GNAT) domain
HHCIPGHA_00440 1.7e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHCIPGHA_00441 1e-255 glnPH2 P ABC transporter permease
HHCIPGHA_00442 7.6e-160 rssA S Phospholipase, patatin family
HHCIPGHA_00443 1.4e-150 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HHCIPGHA_00444 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HHCIPGHA_00445 1.7e-48 S Enterocin A Immunity
HHCIPGHA_00448 5.2e-218 natB CP ABC-2 family transporter protein
HHCIPGHA_00449 9.2e-164 natA S ABC transporter, ATP-binding protein
HHCIPGHA_00450 1.5e-143 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HHCIPGHA_00451 2.2e-306 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHCIPGHA_00452 2.9e-202 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HHCIPGHA_00453 7.4e-121 K response regulator
HHCIPGHA_00454 0.0 V ABC transporter
HHCIPGHA_00455 1.9e-295 V ABC transporter, ATP-binding protein
HHCIPGHA_00456 3.7e-143 XK27_01040 S Protein of unknown function (DUF1129)
HHCIPGHA_00457 3.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHCIPGHA_00458 1.3e-43 yyzM S Bacterial protein of unknown function (DUF951)
HHCIPGHA_00459 2.2e-154 spo0J K Belongs to the ParB family
HHCIPGHA_00460 4.4e-138 soj D Sporulation initiation inhibitor
HHCIPGHA_00461 1e-143 noc K Belongs to the ParB family
HHCIPGHA_00462 4.5e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HHCIPGHA_00463 4.1e-95 cvpA S Colicin V production protein
HHCIPGHA_00464 8.8e-178 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HHCIPGHA_00465 4.4e-149 3.1.3.48 T Tyrosine phosphatase family
HHCIPGHA_00466 1.1e-197 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HHCIPGHA_00467 6.4e-99 azr 1.5.1.36 S NADPH-dependent FMN reductase
HHCIPGHA_00468 1.5e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HHCIPGHA_00469 1e-108 K WHG domain
HHCIPGHA_00470 8e-38
HHCIPGHA_00471 1.2e-261 pipD E Dipeptidase
HHCIPGHA_00472 6.6e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HHCIPGHA_00473 7.4e-173 hrtB V ABC transporter permease
HHCIPGHA_00474 1.9e-92 ygfC K Bacterial regulatory proteins, tetR family
HHCIPGHA_00475 4.6e-111 G phosphoglycerate mutase
HHCIPGHA_00476 2.3e-113 G Phosphoglycerate mutase family
HHCIPGHA_00477 1.1e-138 aroD S Alpha/beta hydrolase family
HHCIPGHA_00478 7.7e-106 S Protein of unknown function (DUF975)
HHCIPGHA_00479 1.1e-136 S Belongs to the UPF0246 family
HHCIPGHA_00480 2.2e-52
HHCIPGHA_00481 1.6e-128
HHCIPGHA_00482 3.1e-159 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HHCIPGHA_00483 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HHCIPGHA_00484 2.2e-142 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
HHCIPGHA_00485 3.1e-153 ybbH_2 K Helix-turn-helix domain, rpiR family
HHCIPGHA_00486 1.1e-169 2.7.7.12 C Domain of unknown function (DUF4931)
HHCIPGHA_00487 2.4e-53 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
HHCIPGHA_00488 1.2e-155
HHCIPGHA_00489 5.9e-165 mdtG EGP Major facilitator Superfamily
HHCIPGHA_00490 2.7e-123 puuD S peptidase C26
HHCIPGHA_00491 6.4e-293 V ABC transporter transmembrane region
HHCIPGHA_00492 2.6e-91 ymdB S Macro domain protein
HHCIPGHA_00493 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HHCIPGHA_00494 3e-297 scrB 3.2.1.26 GH32 G invertase
HHCIPGHA_00495 1.2e-185 scrR K Transcriptional regulator, LacI family
HHCIPGHA_00496 1.2e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
HHCIPGHA_00497 7.1e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HHCIPGHA_00498 2.7e-131 cobQ S glutamine amidotransferase
HHCIPGHA_00499 1.7e-254 yfnA E Amino Acid
HHCIPGHA_00500 2e-163 EG EamA-like transporter family
HHCIPGHA_00501 5.1e-187 asnA 6.3.1.1 F aspartate--ammonia ligase
HHCIPGHA_00502 5e-221 S CAAX protease self-immunity
HHCIPGHA_00503 3.2e-240 steT_1 E amino acid
HHCIPGHA_00504 5e-136 puuD S peptidase C26
HHCIPGHA_00505 3.4e-14
HHCIPGHA_00506 1.8e-72 atkY K Penicillinase repressor
HHCIPGHA_00507 2.5e-62 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HHCIPGHA_00508 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HHCIPGHA_00509 0.0 copA 3.6.3.54 P P-type ATPase
HHCIPGHA_00510 3.9e-151 ropB K Helix-turn-helix XRE-family like proteins
HHCIPGHA_00511 0.0 pepO 3.4.24.71 O Peptidase family M13
HHCIPGHA_00512 1e-284 E Amino acid permease
HHCIPGHA_00513 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HHCIPGHA_00514 1.1e-247 ynbB 4.4.1.1 P aluminum resistance
HHCIPGHA_00515 4.3e-74 K Acetyltransferase (GNAT) domain
HHCIPGHA_00516 1.7e-227 EGP Sugar (and other) transporter
HHCIPGHA_00517 3.7e-64 S Iron-sulphur cluster biosynthesis
HHCIPGHA_00518 2.2e-308 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHCIPGHA_00519 1.6e-277 clcA P chloride
HHCIPGHA_00520 4.3e-269 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHCIPGHA_00521 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HHCIPGHA_00522 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHCIPGHA_00523 8.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHCIPGHA_00524 1.1e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHCIPGHA_00525 1.7e-60 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HHCIPGHA_00526 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HHCIPGHA_00527 5.3e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHCIPGHA_00528 9.4e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHCIPGHA_00529 4.4e-18 yaaA S S4 domain
HHCIPGHA_00530 1.7e-207 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHCIPGHA_00531 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHCIPGHA_00532 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHCIPGHA_00533 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HHCIPGHA_00534 1.7e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHCIPGHA_00535 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHCIPGHA_00536 4.7e-155 corA P CorA-like Mg2+ transporter protein
HHCIPGHA_00537 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HHCIPGHA_00538 1.1e-75 rplI J Binds to the 23S rRNA
HHCIPGHA_00539 3.3e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HHCIPGHA_00540 1.4e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HHCIPGHA_00541 9.3e-214 I Protein of unknown function (DUF2974)
HHCIPGHA_00542 0.0
HHCIPGHA_00543 3.9e-97 yhiD S MgtC family
HHCIPGHA_00545 1.2e-109 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HHCIPGHA_00546 3.6e-20 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HHCIPGHA_00547 1.3e-85 S Protein of unknown function (DUF3278)
HHCIPGHA_00548 6.6e-198 S Aldo keto reductase
HHCIPGHA_00550 4.9e-218 S Sterol carrier protein domain
HHCIPGHA_00551 2.6e-115 ywnB S NAD(P)H-binding
HHCIPGHA_00552 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_00553 4.1e-26 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HHCIPGHA_00554 6.7e-41 K SIS domain
HHCIPGHA_00555 6.5e-51 K SIS domain
HHCIPGHA_00556 9.9e-166 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HHCIPGHA_00559 3.2e-52 P Rhodanese Homology Domain
HHCIPGHA_00560 1e-188
HHCIPGHA_00561 9.5e-124 gntR1 K UTRA
HHCIPGHA_00562 1.5e-67 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HHCIPGHA_00563 7.5e-132 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HHCIPGHA_00564 9.4e-203 csaB M Glycosyl transferases group 1
HHCIPGHA_00565 0.0 tuaG GT2 M Glycosyltransferase like family 2
HHCIPGHA_00566 9.4e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHCIPGHA_00567 3.6e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HHCIPGHA_00568 0.0 pacL 3.6.3.8 P P-type ATPase
HHCIPGHA_00569 5.2e-215 V ABC transporter transmembrane region
HHCIPGHA_00570 9.1e-54 V ABC transporter transmembrane region
HHCIPGHA_00571 7.3e-144
HHCIPGHA_00572 2.7e-224 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HHCIPGHA_00573 2.5e-256 epsU S Polysaccharide biosynthesis protein
HHCIPGHA_00574 3.5e-134 M Glycosyltransferase sugar-binding region containing DXD motif
HHCIPGHA_00575 1.5e-85 ydcK S Belongs to the SprT family
HHCIPGHA_00577 2.6e-101 S ECF transporter, substrate-specific component
HHCIPGHA_00578 2.7e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HHCIPGHA_00579 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HHCIPGHA_00580 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHCIPGHA_00581 1.5e-206 camS S sex pheromone
HHCIPGHA_00582 4.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHCIPGHA_00583 6.4e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHCIPGHA_00584 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHCIPGHA_00585 7.3e-169 yegS 2.7.1.107 G Lipid kinase
HHCIPGHA_00587 8.1e-151 S hydrolase
HHCIPGHA_00588 1.4e-151 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HHCIPGHA_00589 2.2e-138 asp1 S Accessory Sec system protein Asp1
HHCIPGHA_00590 1.6e-10 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
HHCIPGHA_00591 2.2e-169 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
HHCIPGHA_00593 1.8e-40 asp3 S Accessory Sec secretory system ASP3
HHCIPGHA_00594 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHCIPGHA_00595 3.8e-210 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HHCIPGHA_00596 4.2e-189 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HHCIPGHA_00598 1.6e-211 UW Tetratricopeptide repeat
HHCIPGHA_00599 5.2e-26 UW Tetratricopeptide repeat
HHCIPGHA_00601 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_00604 6e-61 yugI 5.3.1.9 J general stress protein
HHCIPGHA_00605 3.8e-176 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HHCIPGHA_00606 2.7e-117 dedA S SNARE-like domain protein
HHCIPGHA_00607 4.2e-104 S Protein of unknown function (DUF1461)
HHCIPGHA_00608 1.4e-147 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HHCIPGHA_00609 3.5e-97 yutD S Protein of unknown function (DUF1027)
HHCIPGHA_00610 1.8e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HHCIPGHA_00611 2e-55
HHCIPGHA_00612 5.2e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HHCIPGHA_00613 1.2e-274 pepV 3.5.1.18 E dipeptidase PepV
HHCIPGHA_00614 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
HHCIPGHA_00615 4.4e-297 V ABC transporter transmembrane region
HHCIPGHA_00616 2.6e-175 ccpA K catabolite control protein A
HHCIPGHA_00617 3.8e-212 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HHCIPGHA_00618 4e-51
HHCIPGHA_00620 1.5e-153 ykuT M mechanosensitive ion channel
HHCIPGHA_00621 2.2e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHCIPGHA_00622 7.9e-114 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHCIPGHA_00623 6.7e-142 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HHCIPGHA_00624 5.4e-68 yslB S Protein of unknown function (DUF2507)
HHCIPGHA_00625 1.1e-52 trxA O Belongs to the thioredoxin family
HHCIPGHA_00626 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHCIPGHA_00627 2.2e-91 cvpA S Colicin V production protein
HHCIPGHA_00628 1.8e-50 yrzB S Belongs to the UPF0473 family
HHCIPGHA_00629 2.3e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHCIPGHA_00630 2.6e-42 yrzL S Belongs to the UPF0297 family
HHCIPGHA_00631 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHCIPGHA_00632 3.3e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HHCIPGHA_00633 2.5e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HHCIPGHA_00634 1.3e-207 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHCIPGHA_00635 4.2e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HHCIPGHA_00636 7.7e-31 yajC U Preprotein translocase
HHCIPGHA_00637 1.4e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHCIPGHA_00638 1.6e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHCIPGHA_00639 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHCIPGHA_00640 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHCIPGHA_00642 4.8e-82 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_00643 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_00644 1.2e-197 E amino acid
HHCIPGHA_00645 0.0 3.1.31.1 M domain protein
HHCIPGHA_00646 2e-253 infB UW LPXTG-motif cell wall anchor domain protein
HHCIPGHA_00647 0.0 infB UW LPXTG-motif cell wall anchor domain protein
HHCIPGHA_00648 0.0 S domain, Protein
HHCIPGHA_00649 1.8e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHCIPGHA_00650 3.8e-102 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HHCIPGHA_00651 9.9e-211 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHCIPGHA_00652 4.4e-239 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HHCIPGHA_00653 1.8e-166 K AI-2E family transporter
HHCIPGHA_00654 1.8e-40
HHCIPGHA_00655 6.7e-159 S Alpha beta hydrolase
HHCIPGHA_00656 0.0 L Helicase C-terminal domain protein
HHCIPGHA_00657 6.7e-161 xth 3.1.11.2 L exodeoxyribonuclease III
HHCIPGHA_00658 2.5e-40 S Transglycosylase associated protein
HHCIPGHA_00660 7.3e-164 P CorA-like Mg2+ transporter protein
HHCIPGHA_00661 0.0 tetP J elongation factor G
HHCIPGHA_00662 2.9e-144 V ABC transporter transmembrane region
HHCIPGHA_00663 2.2e-19
HHCIPGHA_00664 1.2e-152 yitS S EDD domain protein, DegV family
HHCIPGHA_00665 4.9e-136 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HHCIPGHA_00666 3e-130 S Protein of unknown function (DUF975)
HHCIPGHA_00667 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_00668 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_00669 5.1e-91 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HHCIPGHA_00670 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHCIPGHA_00671 6.7e-147 tatD L hydrolase, TatD family
HHCIPGHA_00672 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HHCIPGHA_00673 1.2e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHCIPGHA_00674 7.4e-36 veg S Biofilm formation stimulator VEG
HHCIPGHA_00675 1.5e-145 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HHCIPGHA_00676 1.7e-217 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHCIPGHA_00677 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHCIPGHA_00678 2.9e-176 yvdE K helix_turn _helix lactose operon repressor
HHCIPGHA_00679 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HHCIPGHA_00680 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HHCIPGHA_00681 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HHCIPGHA_00682 4.2e-113 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HHCIPGHA_00683 3.6e-210 msmX P Belongs to the ABC transporter superfamily
HHCIPGHA_00684 5e-229 malE G Bacterial extracellular solute-binding protein
HHCIPGHA_00685 1.6e-252 malF P Binding-protein-dependent transport system inner membrane component
HHCIPGHA_00686 1.3e-154 malG P ABC transporter permease
HHCIPGHA_00687 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HHCIPGHA_00688 1.7e-265 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HHCIPGHA_00689 6e-73 S Domain of unknown function (DUF1934)
HHCIPGHA_00690 1.9e-63 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HHCIPGHA_00691 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHCIPGHA_00692 2.2e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHCIPGHA_00693 3.8e-128 V ABC-type multidrug transport system, ATPase and permease components
HHCIPGHA_00694 1.2e-233 pbuX F xanthine permease
HHCIPGHA_00695 7.6e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHCIPGHA_00696 5.7e-130 K DNA-binding helix-turn-helix protein
HHCIPGHA_00697 2e-299 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HHCIPGHA_00699 1.5e-94 M NlpC P60 family protein
HHCIPGHA_00700 1.1e-98 gmk2 2.7.4.8 F Guanylate kinase
HHCIPGHA_00701 9e-44
HHCIPGHA_00702 7.8e-272 S O-antigen ligase like membrane protein
HHCIPGHA_00703 2.6e-109
HHCIPGHA_00704 2.9e-81 nrdI F NrdI Flavodoxin like
HHCIPGHA_00705 3.7e-179 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHCIPGHA_00706 3.8e-79
HHCIPGHA_00707 4.7e-60 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HHCIPGHA_00708 1.8e-40
HHCIPGHA_00709 9.6e-80 S Threonine/Serine exporter, ThrE
HHCIPGHA_00710 1.5e-138 thrE S Putative threonine/serine exporter
HHCIPGHA_00711 1.9e-281 S ABC transporter, ATP-binding protein
HHCIPGHA_00712 8.3e-61
HHCIPGHA_00713 8.9e-38
HHCIPGHA_00714 3e-212 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HHCIPGHA_00715 0.0 pepF E oligoendopeptidase F
HHCIPGHA_00716 6.8e-71 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHCIPGHA_00718 1e-252 lctP C L-lactate permease
HHCIPGHA_00719 5.1e-134 znuB U ABC 3 transport family
HHCIPGHA_00720 1.1e-116 fhuC P ABC transporter
HHCIPGHA_00721 1.7e-157 psaA P Belongs to the bacterial solute-binding protein 9 family
HHCIPGHA_00722 1.6e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
HHCIPGHA_00723 6.9e-139 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HHCIPGHA_00724 0.0 M domain protein
HHCIPGHA_00725 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HHCIPGHA_00726 1.5e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HHCIPGHA_00727 1.5e-135 fruR K DeoR C terminal sensor domain
HHCIPGHA_00728 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HHCIPGHA_00729 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_00730 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_00731 3.1e-197 S Bacterial membrane protein, YfhO
HHCIPGHA_00732 3.3e-308 S Bacterial membrane protein, YfhO
HHCIPGHA_00733 0.0 aha1 P E1-E2 ATPase
HHCIPGHA_00734 7.2e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
HHCIPGHA_00735 2.2e-257 yjjP S Putative threonine/serine exporter
HHCIPGHA_00736 2e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HHCIPGHA_00737 1e-254 frdC 1.3.5.4 C FAD binding domain
HHCIPGHA_00738 3.8e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HHCIPGHA_00739 2.8e-67 metI P ABC transporter permease
HHCIPGHA_00740 2.1e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHCIPGHA_00741 8.8e-156 metQ1 P Belongs to the nlpA lipoprotein family
HHCIPGHA_00742 3.2e-58 L nuclease
HHCIPGHA_00743 3.8e-143 F DNA/RNA non-specific endonuclease
HHCIPGHA_00744 2.7e-41 K Helix-turn-helix domain
HHCIPGHA_00745 1.1e-310 ybiT S ABC transporter, ATP-binding protein
HHCIPGHA_00746 1.1e-17 S Sugar efflux transporter for intercellular exchange
HHCIPGHA_00747 1.7e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHCIPGHA_00748 1.1e-101 3.6.1.27 I Acid phosphatase homologues
HHCIPGHA_00750 1.1e-155 lysR5 K LysR substrate binding domain
HHCIPGHA_00751 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HHCIPGHA_00752 8.1e-249 G Major Facilitator
HHCIPGHA_00753 2e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHCIPGHA_00754 8.8e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHCIPGHA_00755 6e-120 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHCIPGHA_00756 6.7e-276 yjeM E Amino Acid
HHCIPGHA_00757 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHCIPGHA_00758 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HHCIPGHA_00759 3.5e-123 srtA 3.4.22.70 M sortase family
HHCIPGHA_00760 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHCIPGHA_00761 4.5e-171 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHCIPGHA_00762 0.0 dnaK O Heat shock 70 kDa protein
HHCIPGHA_00763 5.5e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHCIPGHA_00764 2.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHCIPGHA_00765 1.4e-113 S GyrI-like small molecule binding domain
HHCIPGHA_00766 1.6e-277 lsa S ABC transporter
HHCIPGHA_00767 6.4e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HHCIPGHA_00768 5.2e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHCIPGHA_00769 7.9e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHCIPGHA_00770 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHCIPGHA_00771 6e-46 rplGA J ribosomal protein
HHCIPGHA_00772 1.5e-46 ylxR K Protein of unknown function (DUF448)
HHCIPGHA_00773 5.7e-217 nusA K Participates in both transcription termination and antitermination
HHCIPGHA_00774 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
HHCIPGHA_00775 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHCIPGHA_00776 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHCIPGHA_00777 1e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HHCIPGHA_00778 3.8e-137 cdsA 2.7.7.41 S Belongs to the CDS family
HHCIPGHA_00779 2.3e-133 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHCIPGHA_00780 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHCIPGHA_00781 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HHCIPGHA_00782 1.5e-181 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHCIPGHA_00783 6.2e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
HHCIPGHA_00784 7e-184 yabB 2.1.1.223 L Methyltransferase small domain
HHCIPGHA_00785 4.9e-116 plsC 2.3.1.51 I Acyltransferase
HHCIPGHA_00786 1.3e-218 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HHCIPGHA_00787 8.2e-297 mdlB V ABC transporter
HHCIPGHA_00788 0.0 mdlA V ABC transporter
HHCIPGHA_00789 1.9e-30 yneF S Uncharacterised protein family (UPF0154)
HHCIPGHA_00790 1.2e-33 ynzC S UPF0291 protein
HHCIPGHA_00791 7.9e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHCIPGHA_00792 1.8e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
HHCIPGHA_00793 7.2e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HHCIPGHA_00794 1e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HHCIPGHA_00795 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHCIPGHA_00796 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HHCIPGHA_00797 8.1e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHCIPGHA_00798 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HHCIPGHA_00799 5.5e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHCIPGHA_00800 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHCIPGHA_00801 1.4e-286 pipD E Dipeptidase
HHCIPGHA_00802 7.6e-162 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHCIPGHA_00803 0.0 smc D Required for chromosome condensation and partitioning
HHCIPGHA_00804 1.6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHCIPGHA_00805 0.0 oppA E ABC transporter substrate-binding protein
HHCIPGHA_00806 0.0 oppA E ABC transporter substrate-binding protein
HHCIPGHA_00807 2.1e-163 oppC P Binding-protein-dependent transport system inner membrane component
HHCIPGHA_00808 7.5e-180 oppB P ABC transporter permease
HHCIPGHA_00809 4.4e-180 oppF P Belongs to the ABC transporter superfamily
HHCIPGHA_00810 1.1e-192 oppD P Belongs to the ABC transporter superfamily
HHCIPGHA_00811 3.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHCIPGHA_00812 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHCIPGHA_00813 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHCIPGHA_00814 4e-306 yloV S DAK2 domain fusion protein YloV
HHCIPGHA_00815 1.4e-57 asp S Asp23 family, cell envelope-related function
HHCIPGHA_00816 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HHCIPGHA_00817 2.3e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
HHCIPGHA_00818 1.7e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HHCIPGHA_00819 9.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHCIPGHA_00820 0.0 KLT serine threonine protein kinase
HHCIPGHA_00821 4.5e-140 stp 3.1.3.16 T phosphatase
HHCIPGHA_00822 7.2e-242 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHCIPGHA_00823 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHCIPGHA_00824 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHCIPGHA_00825 1.7e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HHCIPGHA_00826 4e-110 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HHCIPGHA_00827 4.6e-48
HHCIPGHA_00828 3.8e-264 recN L May be involved in recombinational repair of damaged DNA
HHCIPGHA_00829 3.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HHCIPGHA_00830 8.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHCIPGHA_00831 3.8e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHCIPGHA_00832 3.4e-250 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHCIPGHA_00833 5.3e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHCIPGHA_00834 3e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHCIPGHA_00835 2.2e-73 yqhY S Asp23 family, cell envelope-related function
HHCIPGHA_00836 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHCIPGHA_00837 8.1e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HHCIPGHA_00838 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HHCIPGHA_00839 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HHCIPGHA_00840 1.1e-62 arsC 1.20.4.1 P Belongs to the ArsC family
HHCIPGHA_00841 1.6e-146 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHCIPGHA_00842 1.4e-240 S Uncharacterized protein conserved in bacteria (DUF2325)
HHCIPGHA_00843 1.2e-12
HHCIPGHA_00844 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HHCIPGHA_00845 2e-92 S ECF-type riboflavin transporter, S component
HHCIPGHA_00846 2.7e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HHCIPGHA_00847 2.2e-57
HHCIPGHA_00848 5.1e-54 K Acetyltransferase (GNAT) domain
HHCIPGHA_00849 7.5e-303 S Predicted membrane protein (DUF2207)
HHCIPGHA_00850 9.8e-190 yhjX P Major Facilitator Superfamily
HHCIPGHA_00851 7.9e-57 I Carboxylesterase family
HHCIPGHA_00852 6.7e-95 I Carboxylesterase family
HHCIPGHA_00853 8.4e-162 rhaS6 K helix_turn_helix, arabinose operon control protein
HHCIPGHA_00854 3.8e-165 2.7.1.2 GK ROK family
HHCIPGHA_00855 1.3e-254 pepC 3.4.22.40 E Peptidase C1-like family
HHCIPGHA_00856 4.6e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
HHCIPGHA_00857 0.0 oppA E ABC transporter substrate-binding protein
HHCIPGHA_00858 1.2e-76 K MerR HTH family regulatory protein
HHCIPGHA_00859 6.8e-265 lmrB EGP Major facilitator Superfamily
HHCIPGHA_00860 2.1e-97 S Domain of unknown function (DUF4811)
HHCIPGHA_00861 6.7e-127 pnb C nitroreductase
HHCIPGHA_00862 9.3e-222 I transferase activity, transferring acyl groups other than amino-acyl groups
HHCIPGHA_00863 3e-107 fic D Fic/DOC family
HHCIPGHA_00864 4.3e-71
HHCIPGHA_00865 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHCIPGHA_00866 5.6e-180 lysA2 M Glycosyl hydrolases family 25
HHCIPGHA_00867 1.7e-67 S Pfam:Phage_holin_6_1
HHCIPGHA_00868 1.2e-42
HHCIPGHA_00869 1.9e-63
HHCIPGHA_00871 9.3e-84
HHCIPGHA_00872 0.0
HHCIPGHA_00873 5.1e-96 S Uncharacterized protein conserved in bacteria (DUF2313)
HHCIPGHA_00874 1.8e-212 S Baseplate J-like protein
HHCIPGHA_00875 2.5e-62 S Protein of unknown function (DUF2634)
HHCIPGHA_00876 2.9e-60 S Protein of unknown function (DUF2577)
HHCIPGHA_00877 2.7e-199 S N-acetylmuramoyl-L-alanine amidase activity
HHCIPGHA_00878 4.7e-112 ygaU GH23 S protein containing LysM domain
HHCIPGHA_00879 3.2e-241 S phage tail tape measure protein
HHCIPGHA_00880 6.4e-67 S Pfam:Phage_TAC_5
HHCIPGHA_00881 1.3e-84 xkdM S Phage tail tube protein
HHCIPGHA_00882 5.6e-220 xkdK S Phage tail sheath C-terminal domain
HHCIPGHA_00883 6.3e-15
HHCIPGHA_00884 1.1e-66
HHCIPGHA_00885 3e-75 S Bacteriophage HK97-gp10, putative tail-component
HHCIPGHA_00886 4.1e-62
HHCIPGHA_00887 5.2e-63
HHCIPGHA_00888 6e-186
HHCIPGHA_00889 6e-89 S Phage minor structural protein GP20
HHCIPGHA_00890 6.1e-33 L NUMOD1 domain
HHCIPGHA_00891 3.3e-176 S Phage Mu protein F like protein
HHCIPGHA_00892 4.2e-264 S Phage portal protein, SPP1 Gp6-like
HHCIPGHA_00893 1.7e-240 S DNA packaging
HHCIPGHA_00894 5e-13 L transposase activity
HHCIPGHA_00895 3.4e-13 queT S QueT transporter
HHCIPGHA_00897 1.7e-96
HHCIPGHA_00898 1.8e-25
HHCIPGHA_00899 1.7e-31
HHCIPGHA_00900 4.7e-45
HHCIPGHA_00903 1.8e-78 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
HHCIPGHA_00905 3.3e-56
HHCIPGHA_00907 2.3e-08
HHCIPGHA_00908 1.9e-33
HHCIPGHA_00910 4.5e-124 S DNA binding
HHCIPGHA_00912 3.7e-25 S sequence-specific DNA binding
HHCIPGHA_00913 8.7e-128 S calcium ion binding
HHCIPGHA_00914 6.6e-49 S Protein of unknown function (DUF1071)
HHCIPGHA_00916 1.5e-55
HHCIPGHA_00917 6.4e-14
HHCIPGHA_00921 6e-60 S Domain of unknown function (DUF771)
HHCIPGHA_00923 1.3e-54 xre K Helix-turn-helix domain
HHCIPGHA_00924 1.9e-80 S Pfam:Peptidase_M78
HHCIPGHA_00925 1.4e-86 S Domain of Unknown Function with PDB structure (DUF3862)
HHCIPGHA_00927 1.5e-123 S Phage integrase family
HHCIPGHA_00929 3e-117 S CAAX protease self-immunity
HHCIPGHA_00930 3.9e-139 S haloacid dehalogenase-like hydrolase
HHCIPGHA_00931 0.0 pepN 3.4.11.2 E aminopeptidase
HHCIPGHA_00932 7.5e-22
HHCIPGHA_00933 2.8e-51
HHCIPGHA_00934 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HHCIPGHA_00935 3.2e-60 K Helix-turn-helix XRE-family like proteins
HHCIPGHA_00936 1.6e-33 K Helix-turn-helix XRE-family like proteins
HHCIPGHA_00937 3.9e-31 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_00938 1.2e-92 GT2,GT4 M family 8
HHCIPGHA_00939 1.6e-97 M family 8
HHCIPGHA_00940 4.6e-97 M family 8
HHCIPGHA_00941 2.2e-109 GT2,GT4 M family 8
HHCIPGHA_00942 3e-99 M family 8
HHCIPGHA_00943 5.6e-55 cpsJ S glycosyl transferase family 2
HHCIPGHA_00944 1.7e-37 cpsJ S glycosyl transferase family 2
HHCIPGHA_00945 1.1e-152 nss M transferase activity, transferring glycosyl groups
HHCIPGHA_00946 6e-94 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HHCIPGHA_00947 8.1e-88 S ECF transporter, substrate-specific component
HHCIPGHA_00948 2.7e-64 S Domain of unknown function (DUF4430)
HHCIPGHA_00949 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HHCIPGHA_00950 3.2e-119 ybhL S Belongs to the BI1 family
HHCIPGHA_00951 7e-142 cbiQ P cobalt transport
HHCIPGHA_00952 0.0 ykoD P ABC transporter, ATP-binding protein
HHCIPGHA_00953 3.3e-95 S UPF0397 protein
HHCIPGHA_00954 4.4e-160 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
HHCIPGHA_00955 4.4e-242 nhaC C Na H antiporter NhaC
HHCIPGHA_00956 4.1e-127 mutF V ABC transporter, ATP-binding protein
HHCIPGHA_00957 2.2e-117 spaE S ABC-2 family transporter protein
HHCIPGHA_00958 1.6e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHCIPGHA_00959 2.9e-179 V Beta-lactamase
HHCIPGHA_00960 2e-138 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
HHCIPGHA_00962 5e-93 3.6.1.55 L NUDIX domain
HHCIPGHA_00963 1.3e-66
HHCIPGHA_00964 1.2e-257 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HHCIPGHA_00966 5.6e-155 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHCIPGHA_00967 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HHCIPGHA_00968 3.3e-56 yheA S Belongs to the UPF0342 family
HHCIPGHA_00969 5.3e-223 yhaO L Ser Thr phosphatase family protein
HHCIPGHA_00970 0.0 L AAA domain
HHCIPGHA_00971 1.6e-185 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HHCIPGHA_00972 3.7e-20 UW LPXTG-motif cell wall anchor domain protein
HHCIPGHA_00973 0.0 UW LPXTG-motif cell wall anchor domain protein
HHCIPGHA_00974 1.6e-219 XK27_04775 S PAS domain
HHCIPGHA_00975 1.6e-103 S Iron-sulfur cluster assembly protein
HHCIPGHA_00976 2e-137 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHCIPGHA_00977 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HHCIPGHA_00978 1.6e-59
HHCIPGHA_00979 3.6e-265 yxbA 6.3.1.12 S ATP-grasp enzyme
HHCIPGHA_00980 0.0 asnB 6.3.5.4 E Asparagine synthase
HHCIPGHA_00981 3.1e-275 S Calcineurin-like phosphoesterase
HHCIPGHA_00982 3.6e-82
HHCIPGHA_00983 9.2e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HHCIPGHA_00984 1.6e-130 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HHCIPGHA_00985 4.3e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HHCIPGHA_00986 8.3e-168 phnD P Phosphonate ABC transporter
HHCIPGHA_00988 3.8e-87 uspA T universal stress protein
HHCIPGHA_00989 2.6e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HHCIPGHA_00990 3.4e-124 XK27_08440 K UTRA domain
HHCIPGHA_00991 1.9e-98 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHCIPGHA_00992 7.4e-88 ntd 2.4.2.6 F Nucleoside
HHCIPGHA_00993 1.9e-186
HHCIPGHA_00995 6.2e-19 rnhA 3.1.26.4 L Caulimovirus viroplasmin
HHCIPGHA_00996 3.2e-68 cjaA ET ABC transporter substrate-binding protein
HHCIPGHA_00997 3.1e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
HHCIPGHA_00998 3.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHCIPGHA_00999 2.5e-244 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HHCIPGHA_01000 2.8e-58 yvoA_1 K Transcriptional regulator, GntR family
HHCIPGHA_01001 4e-122 skfE V ATPases associated with a variety of cellular activities
HHCIPGHA_01002 1.9e-131
HHCIPGHA_01003 4.3e-107
HHCIPGHA_01004 4.7e-22
HHCIPGHA_01005 3e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HHCIPGHA_01006 4.1e-130
HHCIPGHA_01007 1.8e-165
HHCIPGHA_01008 6e-231 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HHCIPGHA_01009 3.2e-50 ybjQ S Belongs to the UPF0145 family
HHCIPGHA_01010 4.6e-159 XK27_05540 S DUF218 domain
HHCIPGHA_01011 4.5e-149 yxeH S hydrolase
HHCIPGHA_01012 8.9e-303 I Protein of unknown function (DUF2974)
HHCIPGHA_01013 6e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHCIPGHA_01014 1.9e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHCIPGHA_01015 4.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HHCIPGHA_01016 1.8e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHCIPGHA_01017 1.1e-178 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HHCIPGHA_01018 1.7e-240 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHCIPGHA_01019 9.6e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HHCIPGHA_01020 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HHCIPGHA_01021 9.6e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHCIPGHA_01022 1.3e-79 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01023 1.3e-40
HHCIPGHA_01024 2.3e-113
HHCIPGHA_01025 9.8e-250 clcA P chloride
HHCIPGHA_01026 2.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHCIPGHA_01027 7.3e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHCIPGHA_01028 1.6e-241 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHCIPGHA_01029 1.9e-43
HHCIPGHA_01030 6e-71 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
HHCIPGHA_01032 9.8e-230 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HHCIPGHA_01033 4.8e-151 K Helix-turn-helix XRE-family like proteins
HHCIPGHA_01034 1.1e-62
HHCIPGHA_01035 8.4e-196 uup S ABC transporter, ATP-binding protein
HHCIPGHA_01036 3.1e-70 uup S ABC transporter, ATP-binding protein
HHCIPGHA_01037 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHCIPGHA_01038 6.3e-102 yvdD 3.2.2.10 S Belongs to the LOG family
HHCIPGHA_01039 1e-78 XK27_02470 K LytTr DNA-binding domain
HHCIPGHA_01040 3.9e-123 liaI S membrane
HHCIPGHA_01041 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHCIPGHA_01042 8.2e-296 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHCIPGHA_01043 0.0 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
HHCIPGHA_01044 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01045 4.4e-222 S Putative peptidoglycan binding domain
HHCIPGHA_01046 4.6e-233 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHCIPGHA_01048 7e-136 V ABC transporter
HHCIPGHA_01049 1.7e-123 V Transport permease protein
HHCIPGHA_01050 9e-114 V ABC-2 type transporter
HHCIPGHA_01051 2.8e-279 E amino acid
HHCIPGHA_01052 8.2e-134 cysA V ABC transporter, ATP-binding protein
HHCIPGHA_01053 0.0 V FtsX-like permease family
HHCIPGHA_01054 5.7e-123 pgm3 G Phosphoglycerate mutase family
HHCIPGHA_01055 5.3e-25
HHCIPGHA_01056 4.3e-146 xth 3.1.11.2 L exodeoxyribonuclease III
HHCIPGHA_01057 0.0 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HHCIPGHA_01058 6.9e-127 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HHCIPGHA_01059 1.3e-143 rpiR1 K Helix-turn-helix domain, rpiR family
HHCIPGHA_01060 2.1e-49 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHCIPGHA_01061 1.3e-235 3.4.16.4 M ErfK YbiS YcfS YnhG
HHCIPGHA_01062 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01063 1.8e-58 K UTRA
HHCIPGHA_01064 2.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HHCIPGHA_01065 1.6e-114 cutC P Participates in the control of copper homeostasis
HHCIPGHA_01066 1.9e-197 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHCIPGHA_01067 5.9e-94 S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
HHCIPGHA_01068 3.5e-177 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
HHCIPGHA_01069 6.3e-254 3.5.1.18 E Peptidase family M20/M25/M40
HHCIPGHA_01070 8.5e-93 ymfC K UTRA
HHCIPGHA_01071 7.4e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHCIPGHA_01072 1.8e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HHCIPGHA_01073 7.7e-70 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHCIPGHA_01074 4.4e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHCIPGHA_01075 9.6e-225 ecsB U ABC transporter
HHCIPGHA_01076 2.7e-132 ecsA V ABC transporter, ATP-binding protein
HHCIPGHA_01077 1.2e-76 hit FG Scavenger mRNA decapping enzyme C-term binding
HHCIPGHA_01078 4.1e-57
HHCIPGHA_01079 5e-33 S YtxH-like protein
HHCIPGHA_01080 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HHCIPGHA_01081 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01082 5.2e-216 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHCIPGHA_01083 2.8e-102 J Acetyltransferase (GNAT) domain
HHCIPGHA_01084 1.5e-106 yjbF S SNARE associated Golgi protein
HHCIPGHA_01085 7.8e-151 I alpha/beta hydrolase fold
HHCIPGHA_01086 8.4e-143 hipB K Helix-turn-helix
HHCIPGHA_01087 6.3e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HHCIPGHA_01088 3.9e-179
HHCIPGHA_01089 1e-122 S SNARE associated Golgi protein
HHCIPGHA_01090 7e-131 cof S haloacid dehalogenase-like hydrolase
HHCIPGHA_01091 0.0 ydgH S MMPL family
HHCIPGHA_01092 1.2e-97 yobS K Bacterial regulatory proteins, tetR family
HHCIPGHA_01094 1.2e-231 cycA E Amino acid permease
HHCIPGHA_01095 2.2e-221 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HHCIPGHA_01096 6.8e-270 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HHCIPGHA_01097 4.1e-69
HHCIPGHA_01098 1.4e-103 4.1.1.44 S Carboxymuconolactone decarboxylase family
HHCIPGHA_01099 0.0 S TerB-C domain
HHCIPGHA_01100 7.3e-250 P P-loop Domain of unknown function (DUF2791)
HHCIPGHA_01101 0.0 lhr L DEAD DEAH box helicase
HHCIPGHA_01102 4.8e-82 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01103 8.8e-99 S TPM domain
HHCIPGHA_01104 4.3e-91 comEB 3.5.4.12 F MafB19-like deaminase
HHCIPGHA_01105 7.5e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHCIPGHA_01106 2.5e-112 E Belongs to the SOS response-associated peptidase family
HHCIPGHA_01108 4.2e-113
HHCIPGHA_01109 1.3e-154 ypbG 2.7.1.2 GK ROK family
HHCIPGHA_01110 1.5e-277 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHCIPGHA_01111 3.4e-269 pts23C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHCIPGHA_01112 3.4e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HHCIPGHA_01113 4.8e-38
HHCIPGHA_01114 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HHCIPGHA_01115 6.8e-133 gmuR K UTRA
HHCIPGHA_01117 1.5e-146 S Bacterial membrane protein, YfhO
HHCIPGHA_01118 7.7e-167 S Bacterial membrane protein, YfhO
HHCIPGHA_01120 7.2e-45
HHCIPGHA_01121 2.5e-75 S zinc-ribbon domain
HHCIPGHA_01122 1.3e-43
HHCIPGHA_01123 3.9e-43 K Helix-turn-helix XRE-family like proteins
HHCIPGHA_01124 1.3e-104 pncA Q Isochorismatase family
HHCIPGHA_01125 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HHCIPGHA_01126 5e-122 alkD L DNA alkylation repair enzyme
HHCIPGHA_01127 1.3e-125 XK27_06785 V ABC transporter, ATP-binding protein
HHCIPGHA_01128 0.0 XK27_06780 V ABC transporter permease
HHCIPGHA_01129 0.0 pepO 3.4.24.71 O Peptidase family M13
HHCIPGHA_01130 5.9e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
HHCIPGHA_01131 1.7e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHCIPGHA_01132 1.7e-276 thrC 4.2.3.1 E Threonine synthase
HHCIPGHA_01133 3e-226 hom1 1.1.1.3 E homoserine dehydrogenase
HHCIPGHA_01134 2e-155 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HHCIPGHA_01135 1.2e-218 glpK_1 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHCIPGHA_01136 3.2e-159 tktA 2.2.1.1 G Transketolase, pyrimidine binding domain
HHCIPGHA_01137 1.7e-140 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
HHCIPGHA_01138 1.6e-161 purR13 K Bacterial regulatory proteins, lacI family
HHCIPGHA_01139 5.3e-278 G isomerase
HHCIPGHA_01140 2.2e-115 celB U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHCIPGHA_01141 1.3e-157 I alpha/beta hydrolase fold
HHCIPGHA_01142 2.1e-217 G Protein of unknown function (DUF4038)
HHCIPGHA_01143 1e-116 drgA C nitroreductase
HHCIPGHA_01144 1.5e-26
HHCIPGHA_01145 1.2e-79 K transcriptional antiterminator
HHCIPGHA_01146 1.5e-184 arbF1 G phosphotransferase system
HHCIPGHA_01147 5.9e-189 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHCIPGHA_01148 4.6e-48
HHCIPGHA_01149 2.5e-37 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HHCIPGHA_01150 2.6e-48 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
HHCIPGHA_01151 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HHCIPGHA_01152 1.4e-133
HHCIPGHA_01153 3.6e-102 speG J Acetyltransferase (GNAT) domain
HHCIPGHA_01154 9.1e-64 K sequence-specific DNA binding
HHCIPGHA_01155 3.4e-77 S Protein of unknown function (DUF975)
HHCIPGHA_01156 1.6e-128 qmcA O prohibitin homologues
HHCIPGHA_01157 2.4e-147 ropB K Helix-turn-helix domain
HHCIPGHA_01158 1.3e-290 V ABC-type multidrug transport system, ATPase and permease components
HHCIPGHA_01159 4e-81 C nitroreductase
HHCIPGHA_01160 9.8e-270 V ABC transporter transmembrane region
HHCIPGHA_01161 3.3e-26
HHCIPGHA_01162 3.2e-77 K Acetyltransferase (GNAT) domain
HHCIPGHA_01163 2.7e-138 S Protein of unknown function (DUF2785)
HHCIPGHA_01164 1.1e-47 S MazG-like family
HHCIPGHA_01165 2.5e-59
HHCIPGHA_01166 6.2e-117 S PFAM Archaeal ATPase
HHCIPGHA_01167 1.1e-69 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHCIPGHA_01168 7.5e-204 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHCIPGHA_01169 2.1e-91 rimL J Acetyltransferase (GNAT) domain
HHCIPGHA_01170 1.2e-82 2.3.1.57 K Acetyltransferase (GNAT) family
HHCIPGHA_01171 9.2e-128 S Alpha/beta hydrolase family
HHCIPGHA_01172 1.5e-182 yxaM EGP Major facilitator Superfamily
HHCIPGHA_01173 3.8e-61 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
HHCIPGHA_01174 2.1e-83 S AAA domain
HHCIPGHA_01175 2.5e-139 2.7.1.89 M Phosphotransferase enzyme family
HHCIPGHA_01177 1.3e-137 2.4.2.3 F Phosphorylase superfamily
HHCIPGHA_01178 1.2e-140 2.4.2.3 F Phosphorylase superfamily
HHCIPGHA_01179 1.3e-81 6.3.3.2 S ASCH
HHCIPGHA_01180 3e-102 5.4.2.11 G Phosphoglycerate mutase family
HHCIPGHA_01181 2.2e-124 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HHCIPGHA_01182 7.3e-120 G Transmembrane secretion effector
HHCIPGHA_01184 3e-266 V ABC-type multidrug transport system, ATPase and permease components
HHCIPGHA_01185 2.1e-248 V ABC-type multidrug transport system, ATPase and permease components
HHCIPGHA_01186 7.5e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HHCIPGHA_01187 4.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HHCIPGHA_01188 1.6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HHCIPGHA_01189 2.5e-164 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HHCIPGHA_01190 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HHCIPGHA_01191 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HHCIPGHA_01192 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HHCIPGHA_01193 9.1e-89 ypmB S Protein conserved in bacteria
HHCIPGHA_01194 1.9e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HHCIPGHA_01195 5.3e-113 dnaD L DnaD domain protein
HHCIPGHA_01196 8e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHCIPGHA_01197 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HHCIPGHA_01198 5.9e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHCIPGHA_01199 4.2e-106 ypsA S Belongs to the UPF0398 family
HHCIPGHA_01200 2e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HHCIPGHA_01201 7.6e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HHCIPGHA_01202 1e-234 cpdA S Calcineurin-like phosphoesterase
HHCIPGHA_01203 1e-173 degV S DegV family
HHCIPGHA_01204 1.4e-56
HHCIPGHA_01205 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HHCIPGHA_01206 3.1e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHCIPGHA_01207 1.3e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHCIPGHA_01208 4.8e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HHCIPGHA_01209 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HHCIPGHA_01210 0.0 FbpA K Fibronectin-binding protein
HHCIPGHA_01211 5.5e-63
HHCIPGHA_01212 2.1e-160 degV S EDD domain protein, DegV family
HHCIPGHA_01213 1.8e-150
HHCIPGHA_01214 1.4e-159 K Transcriptional regulator
HHCIPGHA_01215 2e-202 xerS L Belongs to the 'phage' integrase family
HHCIPGHA_01216 1e-87 yoaK S Protein of unknown function (DUF1275)
HHCIPGHA_01217 2.9e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHCIPGHA_01218 5.1e-273 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HHCIPGHA_01219 3.5e-40 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HHCIPGHA_01220 8.9e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
HHCIPGHA_01221 2e-177 K Transcriptional regulator
HHCIPGHA_01222 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHCIPGHA_01223 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHCIPGHA_01224 4.4e-115 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHCIPGHA_01225 2.2e-108 lacA 2.3.1.79 S Transferase hexapeptide repeat
HHCIPGHA_01226 2.9e-111 magIII L Base excision DNA repair protein, HhH-GPD family
HHCIPGHA_01227 9e-164 akr5f 1.1.1.346 S reductase
HHCIPGHA_01228 8.5e-161 C Aldo/keto reductase family
HHCIPGHA_01229 6.2e-117 V ATPases associated with a variety of cellular activities
HHCIPGHA_01230 1.1e-188 S ABC-2 family transporter protein
HHCIPGHA_01231 1.2e-149
HHCIPGHA_01232 1.2e-37 ropB K Helix-turn-helix domain
HHCIPGHA_01233 2.5e-28
HHCIPGHA_01234 2.5e-116 ybhL S Belongs to the BI1 family
HHCIPGHA_01235 1.6e-35 yrvN L AAA C-terminal domain
HHCIPGHA_01236 1.5e-152 yrvN L AAA C-terminal domain
HHCIPGHA_01237 1.6e-64 XK27_09675 K Acetyltransferase (GNAT) domain
HHCIPGHA_01238 8.4e-196 XK27_00915 C Luciferase-like monooxygenase
HHCIPGHA_01241 1.7e-65 K Transcriptional regulator
HHCIPGHA_01242 2.2e-209 lmrB EGP Major facilitator Superfamily
HHCIPGHA_01243 2.2e-131 S Hydrolases of the alpha beta superfamily
HHCIPGHA_01245 1.7e-148 C Aldo keto reductase
HHCIPGHA_01246 8.4e-294 lmrA 3.6.3.44 V ABC transporter
HHCIPGHA_01247 4.7e-57 K helix_turn_helix multiple antibiotic resistance protein
HHCIPGHA_01248 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HHCIPGHA_01249 7.4e-15 mta K helix_turn_helix, mercury resistance
HHCIPGHA_01250 1.1e-31 mta K helix_turn_helix, mercury resistance
HHCIPGHA_01251 8.8e-10 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HHCIPGHA_01252 5e-59 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HHCIPGHA_01253 1.8e-187 fic S Fic/DOC family
HHCIPGHA_01254 2.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HHCIPGHA_01255 6.2e-236 brnQ U Component of the transport system for branched-chain amino acids
HHCIPGHA_01256 2.9e-72 yphH S Cupin domain
HHCIPGHA_01257 1.1e-88 S Fic/DOC family
HHCIPGHA_01258 1.5e-38 S Protein of unknown function (DUF3021)
HHCIPGHA_01259 4.3e-45 K LytTr DNA-binding domain
HHCIPGHA_01260 2.6e-91 cylB V ABC-2 type transporter
HHCIPGHA_01261 4e-116 cylA V ABC transporter
HHCIPGHA_01262 1.5e-78 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HHCIPGHA_01263 1.4e-220 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
HHCIPGHA_01264 2.3e-47
HHCIPGHA_01265 4.9e-66 K HxlR family
HHCIPGHA_01266 5.4e-58 mntH P H( )-stimulated, divalent metal cation uptake system
HHCIPGHA_01267 3.6e-167 mntH P H( )-stimulated, divalent metal cation uptake system
HHCIPGHA_01268 7.6e-44 yitW S Iron-sulfur cluster assembly protein
HHCIPGHA_01269 1.1e-269 sufB O assembly protein SufB
HHCIPGHA_01270 1.4e-62 nifU C SUF system FeS assembly protein, NifU family
HHCIPGHA_01271 3.5e-190 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHCIPGHA_01272 5e-197 sufD O FeS assembly protein SufD
HHCIPGHA_01273 1.1e-141 sufC O FeS assembly ATPase SufC
HHCIPGHA_01274 2.3e-246 brnQ U Component of the transport system for branched-chain amino acids
HHCIPGHA_01275 1.3e-62 S Putative adhesin
HHCIPGHA_01276 3.6e-108 3.6.1.55 F NUDIX domain
HHCIPGHA_01277 4.8e-108 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HHCIPGHA_01278 4.5e-292
HHCIPGHA_01279 0.0 M domain protein
HHCIPGHA_01280 0.0 bamA UW LPXTG-motif cell wall anchor domain protein
HHCIPGHA_01282 3.6e-291 S domain, Protein
HHCIPGHA_01283 6.9e-14 S domain, Protein
HHCIPGHA_01284 4.1e-13 S reductase
HHCIPGHA_01286 2.7e-90 S Oxidoreductase, aldo keto reductase family protein
HHCIPGHA_01287 3.6e-80 K Transcriptional regulator
HHCIPGHA_01288 9.3e-100 S Protein of unknown function (DUF1211)
HHCIPGHA_01289 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01290 7.1e-245 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HHCIPGHA_01291 1.4e-158 yvgN C Aldo keto reductase
HHCIPGHA_01293 1.6e-129 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHCIPGHA_01294 1.4e-76 K acetyltransferase
HHCIPGHA_01295 5.7e-116 S Putative ABC-transporter type IV
HHCIPGHA_01296 6.7e-94 M LysM domain protein
HHCIPGHA_01297 5.5e-84 M LysM domain protein
HHCIPGHA_01299 1.7e-59 yjgN S Bacterial protein of unknown function (DUF898)
HHCIPGHA_01300 7.2e-186 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HHCIPGHA_01301 2.8e-19 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HHCIPGHA_01305 4.7e-58
HHCIPGHA_01317 2.7e-216 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HHCIPGHA_01318 3e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
HHCIPGHA_01319 1e-182 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHCIPGHA_01320 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HHCIPGHA_01321 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01322 5.6e-221 yifK E Amino acid permease
HHCIPGHA_01323 3.1e-251 yifK E Amino acid permease
HHCIPGHA_01324 1.8e-65 manO S Domain of unknown function (DUF956)
HHCIPGHA_01325 5.6e-172 manN G system, mannose fructose sorbose family IID component
HHCIPGHA_01326 1.3e-124 manY G PTS system
HHCIPGHA_01327 2.8e-185 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HHCIPGHA_01329 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01330 3.6e-142 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHCIPGHA_01331 7.3e-60 S Domain of unknown function (DUF3284)
HHCIPGHA_01346 3.9e-128 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
HHCIPGHA_01347 6.3e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HHCIPGHA_01349 7.6e-09 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HHCIPGHA_01350 1.2e-30 N PFAM Uncharacterised protein family UPF0150
HHCIPGHA_01352 1.8e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHCIPGHA_01353 2.4e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HHCIPGHA_01354 7.8e-129 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HHCIPGHA_01355 2.6e-86 folT S ECF transporter, substrate-specific component
HHCIPGHA_01356 5.1e-128 fat 3.1.2.21 I Acyl-ACP thioesterase
HHCIPGHA_01357 6.3e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHCIPGHA_01358 4.9e-57 yabA L Involved in initiation control of chromosome replication
HHCIPGHA_01359 1.8e-153 holB 2.7.7.7 L DNA polymerase III
HHCIPGHA_01360 1e-51 yaaQ S Cyclic-di-AMP receptor
HHCIPGHA_01361 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHCIPGHA_01362 2.4e-26 S Protein of unknown function (DUF2508)
HHCIPGHA_01363 6.2e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHCIPGHA_01364 5.9e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHCIPGHA_01365 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHCIPGHA_01366 4.2e-80 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHCIPGHA_01367 1.9e-23
HHCIPGHA_01368 3.6e-111 rsmC 2.1.1.172 J Methyltransferase
HHCIPGHA_01369 1.6e-32
HHCIPGHA_01370 4.5e-147 kcsA P Ion transport protein
HHCIPGHA_01371 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HHCIPGHA_01372 3.1e-96 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHCIPGHA_01373 3.9e-142 aatB ET ABC transporter substrate-binding protein
HHCIPGHA_01374 9.7e-115 glnQ 3.6.3.21 E ABC transporter
HHCIPGHA_01375 4.6e-109 glnP P ABC transporter permease
HHCIPGHA_01376 1.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HHCIPGHA_01377 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HHCIPGHA_01378 2e-100 nusG K Participates in transcription elongation, termination and antitermination
HHCIPGHA_01379 9.1e-12 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HHCIPGHA_01380 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HHCIPGHA_01381 6.5e-190 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHCIPGHA_01382 6.2e-227 G Major Facilitator Superfamily
HHCIPGHA_01383 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHCIPGHA_01384 4.1e-24 K Helix-turn-helix XRE-family like proteins
HHCIPGHA_01385 6.9e-17
HHCIPGHA_01386 4.1e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HHCIPGHA_01387 5.7e-283 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HHCIPGHA_01388 1.7e-34
HHCIPGHA_01389 1.2e-97 yvrI K sigma factor activity
HHCIPGHA_01390 1.7e-289 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HHCIPGHA_01391 5.4e-290 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HHCIPGHA_01392 1.9e-56 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HHCIPGHA_01393 5.9e-152 lacT K PRD domain
HHCIPGHA_01394 1.2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHCIPGHA_01395 3.8e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHCIPGHA_01396 5.5e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHCIPGHA_01397 5.3e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHCIPGHA_01398 4.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHCIPGHA_01399 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HHCIPGHA_01400 2.4e-256 pepC 3.4.22.40 E Peptidase C1-like family
HHCIPGHA_01401 1.7e-184 S AAA domain
HHCIPGHA_01402 5.2e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHCIPGHA_01403 6e-25
HHCIPGHA_01404 2.2e-41
HHCIPGHA_01405 3.8e-154 czcD P cation diffusion facilitator family transporter
HHCIPGHA_01406 2.6e-52 K Transcriptional regulator, ArsR family
HHCIPGHA_01407 3.7e-128 pgm3 G Belongs to the phosphoglycerate mutase family
HHCIPGHA_01408 3.8e-110 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HHCIPGHA_01409 4.6e-160 1.6.5.2 GM NmrA-like family
HHCIPGHA_01410 1.2e-105 spaG S ABC-2 family transporter protein
HHCIPGHA_01411 2.2e-70 spaE S ABC-2 family transporter protein
HHCIPGHA_01412 7.6e-113 mutF V ABC transporter, ATP-binding protein
HHCIPGHA_01413 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HHCIPGHA_01414 1e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHCIPGHA_01415 3.5e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHCIPGHA_01416 1.4e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHCIPGHA_01417 2.3e-159 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHCIPGHA_01418 9e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHCIPGHA_01419 1.3e-61 rplQ J Ribosomal protein L17
HHCIPGHA_01420 1.3e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHCIPGHA_01421 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HHCIPGHA_01422 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHCIPGHA_01423 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HHCIPGHA_01424 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHCIPGHA_01425 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHCIPGHA_01426 5.8e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHCIPGHA_01427 1.3e-70 rplO J Binds to the 23S rRNA
HHCIPGHA_01428 1.4e-23 rpmD J Ribosomal protein L30
HHCIPGHA_01429 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHCIPGHA_01430 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHCIPGHA_01431 5e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHCIPGHA_01432 2.7e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHCIPGHA_01433 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHCIPGHA_01434 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHCIPGHA_01435 1.4e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHCIPGHA_01436 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHCIPGHA_01437 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHCIPGHA_01438 1.8e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HHCIPGHA_01439 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHCIPGHA_01440 3.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHCIPGHA_01441 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHCIPGHA_01442 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHCIPGHA_01443 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHCIPGHA_01444 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHCIPGHA_01445 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
HHCIPGHA_01446 2.2e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHCIPGHA_01447 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HHCIPGHA_01448 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HHCIPGHA_01449 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HHCIPGHA_01450 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HHCIPGHA_01451 9.8e-110 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HHCIPGHA_01452 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHCIPGHA_01453 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHCIPGHA_01454 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HHCIPGHA_01456 1.6e-08
HHCIPGHA_01457 1.5e-12 L Belongs to the 'phage' integrase family
HHCIPGHA_01458 8.3e-161 L Belongs to the 'phage' integrase family
HHCIPGHA_01459 3.2e-22 S DNA binding domain, excisionase family
HHCIPGHA_01460 2.4e-115 repB EP Plasmid replication protein
HHCIPGHA_01462 2e-136 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HHCIPGHA_01463 1.1e-27
HHCIPGHA_01464 7.9e-33
HHCIPGHA_01465 1.7e-06 D LPXTG cell wall anchor motif
HHCIPGHA_01466 2.9e-295 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HHCIPGHA_01467 3.4e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHCIPGHA_01468 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHCIPGHA_01469 0.0 S membrane
HHCIPGHA_01470 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHCIPGHA_01471 1.8e-245 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHCIPGHA_01472 4.9e-60 yabR J S1 RNA binding domain
HHCIPGHA_01473 2.3e-60 divIC D Septum formation initiator
HHCIPGHA_01474 4.1e-34 yabO J S4 domain protein
HHCIPGHA_01475 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHCIPGHA_01476 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHCIPGHA_01477 8.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HHCIPGHA_01478 2.4e-124 S (CBS) domain
HHCIPGHA_01479 6.9e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHCIPGHA_01480 8.5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HHCIPGHA_01481 8.5e-260 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHCIPGHA_01482 8.5e-262 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHCIPGHA_01483 8e-41 rpmE2 J Ribosomal protein L31
HHCIPGHA_01484 6e-283 ybeC E amino acid
HHCIPGHA_01485 5.8e-135 XK27_08845 S ABC transporter, ATP-binding protein
HHCIPGHA_01486 2.4e-140 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HHCIPGHA_01487 9.5e-178 ABC-SBP S ABC transporter
HHCIPGHA_01488 0.0 rafA 3.2.1.22 G alpha-galactosidase
HHCIPGHA_01489 1.2e-45 S Domain of unknown function (DUF3284)
HHCIPGHA_01490 4.7e-209 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHCIPGHA_01491 2.4e-24 K Periplasmic binding protein-like domain
HHCIPGHA_01492 4.8e-80 K Periplasmic binding protein-like domain
HHCIPGHA_01493 2.3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHCIPGHA_01494 9.4e-280 pipD E Dipeptidase
HHCIPGHA_01495 5.4e-08
HHCIPGHA_01496 1.3e-78
HHCIPGHA_01497 2.1e-65 S Putative adhesin
HHCIPGHA_01498 1.7e-219 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHCIPGHA_01499 1.8e-38
HHCIPGHA_01500 2.5e-185 yfdV S Membrane transport protein
HHCIPGHA_01501 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HHCIPGHA_01502 4.5e-271 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HHCIPGHA_01503 2.6e-94
HHCIPGHA_01504 1.5e-81 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHCIPGHA_01505 3e-50
HHCIPGHA_01507 4.8e-43 yjdF S Protein of unknown function (DUF2992)
HHCIPGHA_01508 2.6e-111 1.6.5.2 S Flavodoxin-like fold
HHCIPGHA_01509 6.5e-93 K Bacterial regulatory proteins, tetR family
HHCIPGHA_01510 4.8e-28 doc S Fic/DOC family
HHCIPGHA_01511 1.1e-154 K Helix-turn-helix
HHCIPGHA_01512 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01520 2.1e-47 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HHCIPGHA_01525 9.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHCIPGHA_01526 1.8e-257 qacA EGP Major facilitator Superfamily
HHCIPGHA_01527 4e-116 3.6.1.27 I Acid phosphatase homologues
HHCIPGHA_01528 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHCIPGHA_01529 1e-301 ytgP S Polysaccharide biosynthesis protein
HHCIPGHA_01530 6.9e-217 I Protein of unknown function (DUF2974)
HHCIPGHA_01531 3.4e-119
HHCIPGHA_01532 6e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHCIPGHA_01533 8.3e-125 M ErfK YbiS YcfS YnhG
HHCIPGHA_01534 2.2e-168 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHCIPGHA_01535 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HHCIPGHA_01536 6.5e-173 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HHCIPGHA_01537 5.6e-47
HHCIPGHA_01538 2.7e-33 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
HHCIPGHA_01539 7.6e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HHCIPGHA_01541 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HHCIPGHA_01542 1.3e-127 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
HHCIPGHA_01543 7.8e-109 ylbE GM NAD(P)H-binding
HHCIPGHA_01544 6.9e-83 yebR 1.8.4.14 T GAF domain-containing protein
HHCIPGHA_01545 2.1e-41 ybbH_2 K Helix-turn-helix domain, rpiR family
HHCIPGHA_01546 1.9e-232 G phosphotransferase system
HHCIPGHA_01547 4e-241 bglH 3.2.1.86 GT1 G Glycosyl hydrolase family 1
HHCIPGHA_01548 4.1e-189 S Bacteriocin helveticin-J
HHCIPGHA_01549 2.2e-102 tag 3.2.2.20 L glycosylase
HHCIPGHA_01550 6.2e-163 mleP3 S Membrane transport protein
HHCIPGHA_01551 6.2e-124 S CAAX amino terminal protease
HHCIPGHA_01552 2.6e-143 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HHCIPGHA_01553 3e-252 emrY EGP Major facilitator Superfamily
HHCIPGHA_01554 2e-256 emrY EGP Major facilitator Superfamily
HHCIPGHA_01555 3.6e-256 V ABC-type multidrug transport system, ATPase and permease components
HHCIPGHA_01556 2.2e-274 V ABC-type multidrug transport system, ATPase and permease components
HHCIPGHA_01557 1.1e-68 yxdD K Bacterial regulatory proteins, tetR family
HHCIPGHA_01558 0.0 4.2.1.53 S Myosin-crossreactive antigen
HHCIPGHA_01559 4.1e-77 2.3.1.128 K acetyltransferase
HHCIPGHA_01560 1.5e-141 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HHCIPGHA_01561 5.4e-103 yagU S Protein of unknown function (DUF1440)
HHCIPGHA_01562 1.1e-144 S hydrolase
HHCIPGHA_01563 1.7e-132 K Transcriptional regulator
HHCIPGHA_01564 2.3e-146 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01565 5.7e-33 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01567 1.6e-183 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHCIPGHA_01568 2.6e-139 G Pts system
HHCIPGHA_01569 1.5e-21 K DNA-binding transcription factor activity
HHCIPGHA_01570 2.3e-25 S PFAM Archaeal ATPase
HHCIPGHA_01571 4.7e-241 pyrP F Permease
HHCIPGHA_01572 1.3e-137 lacR K DeoR C terminal sensor domain
HHCIPGHA_01573 9.4e-74 lacA 5.3.1.26 G Ribose/Galactose Isomerase
HHCIPGHA_01574 1.9e-106 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HHCIPGHA_01575 1.6e-128 S Domain of unknown function (DUF4867)
HHCIPGHA_01576 1.6e-85 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HHCIPGHA_01577 6.3e-51 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HHCIPGHA_01578 7.7e-266 gatC G PTS system sugar-specific permease component
HHCIPGHA_01579 2.9e-38
HHCIPGHA_01580 1.1e-142 lacT K CAT RNA binding domain
HHCIPGHA_01581 3.6e-55 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HHCIPGHA_01582 5.7e-303 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HHCIPGHA_01583 2.5e-288 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HHCIPGHA_01584 3e-193 S PFAM Archaeal ATPase
HHCIPGHA_01585 2.1e-84 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
HHCIPGHA_01586 7.7e-158 glsA 3.5.1.2 E Belongs to the glutaminase family
HHCIPGHA_01587 9.3e-69 K AraC-like ligand binding domain
HHCIPGHA_01588 3.6e-102 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HHCIPGHA_01589 1.4e-11 G Pts system
HHCIPGHA_01590 2.1e-205 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHCIPGHA_01591 2.3e-31 ptbA G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HHCIPGHA_01592 5.3e-110 3.6.1.27 I Acid phosphatase homologues
HHCIPGHA_01593 8.7e-275 E Phospholipase B
HHCIPGHA_01594 4e-65 pepC 3.4.22.40 E Peptidase C1-like family
HHCIPGHA_01595 8.8e-168 pepC 3.4.22.40 E Peptidase C1-like family
HHCIPGHA_01596 2.3e-285 gadC E Contains amino acid permease domain
HHCIPGHA_01597 3.9e-238 yagE E amino acid
HHCIPGHA_01598 3.2e-250 ade 3.5.4.2 F Adenine deaminase C-terminal domain
HHCIPGHA_01599 5.7e-137 potD2 P ABC transporter
HHCIPGHA_01600 1.8e-150 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHCIPGHA_01601 6.5e-113 potC3 E Binding-protein-dependent transport system inner membrane component
HHCIPGHA_01602 3.9e-108 potB E Binding-protein-dependent transport system inner membrane component
HHCIPGHA_01603 3.6e-70 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHCIPGHA_01604 1.3e-293 E Amino acid permease
HHCIPGHA_01605 2.2e-216 mdtG EGP Major facilitator Superfamily
HHCIPGHA_01606 1.2e-29
HHCIPGHA_01607 1.3e-70 K helix_turn_helix multiple antibiotic resistance protein
HHCIPGHA_01608 1e-78
HHCIPGHA_01609 2e-205 pepA E M42 glutamyl aminopeptidase
HHCIPGHA_01610 5.9e-88 2.7.1.191 G PTS system sorbose subfamily IIB component
HHCIPGHA_01611 1.2e-103 G PTS system sorbose-specific iic component
HHCIPGHA_01612 3.4e-152 G PTS system mannose/fructose/sorbose family IID component
HHCIPGHA_01613 2e-71 2.7.1.191 G PTS system fructose IIA component
HHCIPGHA_01614 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HHCIPGHA_01615 2.4e-181 lacI3 K helix_turn _helix lactose operon repressor
HHCIPGHA_01616 0.0 3.2.1.177 GH31 G Glycosyl hydrolases family 31
HHCIPGHA_01617 6.2e-266 dtpT U amino acid peptide transporter
HHCIPGHA_01618 2.9e-208 naiP EGP Major facilitator Superfamily
HHCIPGHA_01619 3.2e-150 S Alpha beta hydrolase
HHCIPGHA_01620 1.1e-74 K Transcriptional regulator, MarR family
HHCIPGHA_01621 4.1e-301 XK27_09600 V ABC transporter, ATP-binding protein
HHCIPGHA_01622 0.0 V ABC transporter transmembrane region
HHCIPGHA_01623 3.8e-148 glnH ET ABC transporter
HHCIPGHA_01624 2.7e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHCIPGHA_01625 6.5e-148 glnH ET ABC transporter
HHCIPGHA_01626 3.2e-110 gluC P ABC transporter permease
HHCIPGHA_01627 3.4e-107 glnP P ABC transporter permease
HHCIPGHA_01628 6.7e-42 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHCIPGHA_01629 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HHCIPGHA_01630 3.1e-130 treR K UTRA
HHCIPGHA_01631 0.0 treB 2.7.1.211 G phosphotransferase system
HHCIPGHA_01632 3.2e-83 S Putative adhesin
HHCIPGHA_01633 8.3e-111 udk 2.7.1.48 F Cytidine monophosphokinase
HHCIPGHA_01634 9.8e-49 EGP Major facilitator superfamily
HHCIPGHA_01635 7.7e-154 EGP Major facilitator superfamily
HHCIPGHA_01637 8.3e-190 2.7.13.3 T GHKL domain
HHCIPGHA_01638 5.9e-122 K LytTr DNA-binding domain
HHCIPGHA_01639 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HHCIPGHA_01640 5.5e-35 M Transport protein ComB
HHCIPGHA_01641 2e-32 S Enterocin A Immunity
HHCIPGHA_01643 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01644 2.1e-47 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HHCIPGHA_01645 5.1e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHCIPGHA_01646 7.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HHCIPGHA_01647 2.7e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHCIPGHA_01648 8.6e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHCIPGHA_01649 2.5e-35
HHCIPGHA_01650 1.2e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHCIPGHA_01651 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHCIPGHA_01652 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHCIPGHA_01653 5.3e-124 comFC S Competence protein
HHCIPGHA_01654 3.6e-238 comFA L Helicase C-terminal domain protein
HHCIPGHA_01655 5.6e-118 yvyE 3.4.13.9 S YigZ family
HHCIPGHA_01656 5.9e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
HHCIPGHA_01657 1.2e-209 rny S Endoribonuclease that initiates mRNA decay
HHCIPGHA_01658 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHCIPGHA_01659 1.4e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHCIPGHA_01660 3.1e-123 ymfM S Helix-turn-helix domain
HHCIPGHA_01661 1e-128 IQ Enoyl-(Acyl carrier protein) reductase
HHCIPGHA_01662 4.6e-230 S Peptidase M16
HHCIPGHA_01663 8.4e-229 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HHCIPGHA_01664 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HHCIPGHA_01665 7.8e-76 WQ51_03320 S Protein of unknown function (DUF1149)
HHCIPGHA_01666 3.5e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHCIPGHA_01667 5.4e-212 yubA S AI-2E family transporter
HHCIPGHA_01668 9.9e-67 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HHCIPGHA_01669 4.1e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HHCIPGHA_01670 6.2e-232 N Uncharacterized conserved protein (DUF2075)
HHCIPGHA_01671 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HHCIPGHA_01672 5.4e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHCIPGHA_01673 4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHCIPGHA_01674 6.7e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
HHCIPGHA_01675 7.4e-112 yjbK S CYTH
HHCIPGHA_01676 7.7e-106 yjbH Q Thioredoxin
HHCIPGHA_01677 1.2e-49 coiA 3.6.4.12 S Competence protein
HHCIPGHA_01678 7.9e-79 coiA 3.6.4.12 S Competence protein
HHCIPGHA_01679 2.1e-117 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HHCIPGHA_01680 4.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHCIPGHA_01681 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHCIPGHA_01682 4.2e-40 ptsH G phosphocarrier protein HPR
HHCIPGHA_01683 6.9e-26
HHCIPGHA_01684 0.0 clpE O Belongs to the ClpA ClpB family
HHCIPGHA_01685 4.3e-43 XK27_09445 S Domain of unknown function (DUF1827)
HHCIPGHA_01686 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HHCIPGHA_01687 6.2e-157 hlyX S Transporter associated domain
HHCIPGHA_01688 3e-78
HHCIPGHA_01689 1.1e-89
HHCIPGHA_01690 2.4e-112 ygaC J Belongs to the UPF0374 family
HHCIPGHA_01691 1.5e-141 recX 2.4.1.337 GT4 S Regulatory protein RecX
HHCIPGHA_01692 1.2e-258 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHCIPGHA_01693 6e-191 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HHCIPGHA_01694 2.6e-16 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HHCIPGHA_01695 3.4e-217 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HHCIPGHA_01696 4.8e-213 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HHCIPGHA_01697 3.8e-176 D Alpha beta
HHCIPGHA_01698 2.4e-07
HHCIPGHA_01699 1.2e-151 S haloacid dehalogenase-like hydrolase
HHCIPGHA_01700 3.1e-204 EGP Major facilitator Superfamily
HHCIPGHA_01701 1.4e-261 glnA 6.3.1.2 E glutamine synthetase
HHCIPGHA_01702 3.1e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHCIPGHA_01703 8.1e-19 S Protein of unknown function (DUF3042)
HHCIPGHA_01704 2.6e-57 yqhL P Rhodanese-like protein
HHCIPGHA_01705 3e-34 yqgQ S Bacterial protein of unknown function (DUF910)
HHCIPGHA_01706 1.5e-118 gluP 3.4.21.105 S Rhomboid family
HHCIPGHA_01707 1.5e-84 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHCIPGHA_01708 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HHCIPGHA_01709 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HHCIPGHA_01710 0.0 S membrane
HHCIPGHA_01711 2e-64 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHCIPGHA_01712 1.4e-203 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHCIPGHA_01713 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHCIPGHA_01714 8.1e-204 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHCIPGHA_01715 7.3e-64 yodB K Transcriptional regulator, HxlR family
HHCIPGHA_01716 2.8e-137 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHCIPGHA_01717 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HHCIPGHA_01718 2.7e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHCIPGHA_01719 1.9e-281 arlS 2.7.13.3 T Histidine kinase
HHCIPGHA_01720 1.1e-130 K response regulator
HHCIPGHA_01721 5.2e-93 yceD S Uncharacterized ACR, COG1399
HHCIPGHA_01722 1.9e-217 ylbM S Belongs to the UPF0348 family
HHCIPGHA_01723 8.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHCIPGHA_01724 2.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HHCIPGHA_01725 4.4e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHCIPGHA_01726 1.2e-208 yqeH S Ribosome biogenesis GTPase YqeH
HHCIPGHA_01727 9.6e-89 yqeG S HAD phosphatase, family IIIA
HHCIPGHA_01728 7.8e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HHCIPGHA_01729 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHCIPGHA_01730 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HHCIPGHA_01731 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHCIPGHA_01732 5.3e-128 S domain protein
HHCIPGHA_01733 8e-163 V ABC transporter
HHCIPGHA_01734 5.7e-71 S Protein of unknown function (DUF3021)
HHCIPGHA_01735 1.3e-70 K LytTr DNA-binding domain
HHCIPGHA_01736 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHCIPGHA_01737 2.8e-160 dnaI L Primosomal protein DnaI
HHCIPGHA_01738 1.3e-243 dnaB L Replication initiation and membrane attachment
HHCIPGHA_01739 5.9e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHCIPGHA_01740 1e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHCIPGHA_01741 2.2e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHCIPGHA_01742 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHCIPGHA_01743 1e-226 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HHCIPGHA_01744 1.2e-210 EGP Major facilitator Superfamily
HHCIPGHA_01745 1.2e-68 rmaI K Transcriptional regulator
HHCIPGHA_01746 1e-36
HHCIPGHA_01747 1.3e-151 levD G PTS system mannose/fructose/sorbose family IID component
HHCIPGHA_01748 1.5e-139 M PTS system sorbose-specific iic component
HHCIPGHA_01749 1.1e-94 2.7.1.191 G PTS system sorbose subfamily IIB component
HHCIPGHA_01750 1.4e-67 levA G PTS system fructose IIA component
HHCIPGHA_01751 1.7e-147 rbsB G Periplasmic binding protein domain
HHCIPGHA_01752 6.8e-200 baeS F Sensor histidine kinase
HHCIPGHA_01753 3e-111 baeR K helix_turn_helix, Lux Regulon
HHCIPGHA_01754 1.2e-173 G Bacterial extracellular solute-binding protein
HHCIPGHA_01755 2.1e-126 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHCIPGHA_01756 2.5e-43 K UTRA
HHCIPGHA_01757 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01758 1.6e-50 K Bacterial regulatory proteins, tetR family
HHCIPGHA_01759 1.2e-120 S Alpha/beta hydrolase family
HHCIPGHA_01760 1.7e-219 yrvN L AAA C-terminal domain
HHCIPGHA_01762 3.6e-65 K LytTr DNA-binding domain
HHCIPGHA_01763 1.7e-48 S Protein of unknown function (DUF3021)
HHCIPGHA_01764 2.8e-115 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HHCIPGHA_01765 8.2e-307 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HHCIPGHA_01766 2e-94 K Acetyltransferase (GNAT) domain
HHCIPGHA_01767 1.1e-130 ybbM S Uncharacterised protein family (UPF0014)
HHCIPGHA_01768 5.1e-108 ybbL S ABC transporter, ATP-binding protein
HHCIPGHA_01770 3.5e-100 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHCIPGHA_01771 1.5e-40 K peptidyl-tyrosine sulfation
HHCIPGHA_01772 1.1e-40
HHCIPGHA_01773 4.2e-47
HHCIPGHA_01774 4.4e-58 lsa S ABC transporter
HHCIPGHA_01775 9.9e-109 S Alpha beta hydrolase
HHCIPGHA_01776 1.5e-186 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HHCIPGHA_01777 2.5e-84 S NADPH-dependent FMN reductase
HHCIPGHA_01778 2.4e-145 K Transcriptional regulator
HHCIPGHA_01779 2.9e-177 MA20_14895 S Conserved hypothetical protein 698
HHCIPGHA_01780 1.5e-61
HHCIPGHA_01782 7.7e-100 S LexA-binding, inner membrane-associated putative hydrolase
HHCIPGHA_01783 2.1e-95 K LysR substrate binding domain
HHCIPGHA_01784 4.5e-179 lacX 5.1.3.3 G Aldose 1-epimerase
HHCIPGHA_01785 5.3e-251 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HHCIPGHA_01786 9.7e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HHCIPGHA_01787 6.8e-170 xerC D Phage integrase, N-terminal SAM-like domain
HHCIPGHA_01788 7.7e-244 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HHCIPGHA_01789 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHCIPGHA_01790 5.8e-152 dprA LU DNA protecting protein DprA
HHCIPGHA_01791 3.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHCIPGHA_01792 3.5e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHCIPGHA_01793 1.5e-264 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HHCIPGHA_01794 2e-35 yozE S Belongs to the UPF0346 family
HHCIPGHA_01795 1e-151 DegV S Uncharacterised protein, DegV family COG1307
HHCIPGHA_01796 4.9e-114 hlyIII S protein, hemolysin III
HHCIPGHA_01797 1.5e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHCIPGHA_01798 1.2e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHCIPGHA_01799 2.9e-176 S cog cog1373
HHCIPGHA_01800 0.0 1.3.5.4 C FMN_bind
HHCIPGHA_01801 0.0 S Protein of unknown function DUF262
HHCIPGHA_01802 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
HHCIPGHA_01803 1.4e-60 3.1.21.3 V Type I restriction modification DNA specificity domain
HHCIPGHA_01804 2.7e-177 L Belongs to the 'phage' integrase family
HHCIPGHA_01805 1.5e-70 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HHCIPGHA_01806 3.4e-288 hsdM 2.1.1.72 V type I restriction-modification system
HHCIPGHA_01807 4.2e-231 S Tetratricopeptide repeat protein
HHCIPGHA_01808 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHCIPGHA_01809 1.8e-240 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HHCIPGHA_01810 3e-218 rpsA 1.17.7.4 J Ribosomal protein S1
HHCIPGHA_01811 6.9e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HHCIPGHA_01812 2.9e-97 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HHCIPGHA_01813 2.8e-57 M Lysin motif
HHCIPGHA_01814 4.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHCIPGHA_01815 2.9e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHCIPGHA_01816 3.3e-135 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHCIPGHA_01817 3.5e-61 ribT K acetyltransferase
HHCIPGHA_01818 1.8e-167 xerD D recombinase XerD
HHCIPGHA_01819 2.8e-165 cvfB S S1 domain
HHCIPGHA_01820 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HHCIPGHA_01821 3.6e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHCIPGHA_01822 0.0 dnaE 2.7.7.7 L DNA polymerase
HHCIPGHA_01823 2.1e-28 S Protein of unknown function (DUF2929)
HHCIPGHA_01824 2.4e-308 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HHCIPGHA_01825 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HHCIPGHA_01826 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
HHCIPGHA_01827 1.8e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HHCIPGHA_01828 5.7e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHCIPGHA_01829 0.0 oatA I Acyltransferase
HHCIPGHA_01830 8.6e-240 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHCIPGHA_01831 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHCIPGHA_01832 1.7e-173 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HHCIPGHA_01833 1.9e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
HHCIPGHA_01834 2.1e-114 GM NmrA-like family
HHCIPGHA_01835 2.5e-245 yagE E amino acid
HHCIPGHA_01836 7.4e-80 S Rib/alpha-like repeat
HHCIPGHA_01837 1.5e-62 S Domain of unknown function DUF1828
HHCIPGHA_01838 1e-66
HHCIPGHA_01839 1.5e-30
HHCIPGHA_01840 5.7e-82 mutT 3.6.1.55 F NUDIX domain
HHCIPGHA_01841 4.1e-73
HHCIPGHA_01842 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HHCIPGHA_01843 2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HHCIPGHA_01844 3.1e-72 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHCIPGHA_01845 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHCIPGHA_01846 1e-63
HHCIPGHA_01847 2.8e-171 prmA J Ribosomal protein L11 methyltransferase
HHCIPGHA_01848 1.5e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHCIPGHA_01849 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01850 6.9e-251 yfnA E Amino Acid
HHCIPGHA_01851 0.0 clpE2 O AAA domain (Cdc48 subfamily)
HHCIPGHA_01852 3.6e-155 S Alpha/beta hydrolase of unknown function (DUF915)
HHCIPGHA_01853 2.3e-240 pts13C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHCIPGHA_01854 9.2e-39
HHCIPGHA_01855 1.8e-215 lmrP E Major Facilitator Superfamily
HHCIPGHA_01856 1.7e-173 pbpX2 V Beta-lactamase
HHCIPGHA_01857 1.7e-251 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HHCIPGHA_01858 3.9e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHCIPGHA_01859 2.1e-235 dltB M MBOAT, membrane-bound O-acyltransferase family
HHCIPGHA_01860 2e-288 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHCIPGHA_01862 3.7e-42
HHCIPGHA_01863 1.1e-198 ywhK S Membrane
HHCIPGHA_01865 1.3e-57
HHCIPGHA_01867 7.9e-85 ykuL S (CBS) domain
HHCIPGHA_01868 1.9e-164 cadA P P-type ATPase
HHCIPGHA_01869 8.6e-140 cadA P P-type ATPase
HHCIPGHA_01870 3.5e-200 napA P Sodium/hydrogen exchanger family
HHCIPGHA_01872 3.6e-272 V ABC transporter transmembrane region
HHCIPGHA_01873 5.5e-158 mutR K Helix-turn-helix XRE-family like proteins
HHCIPGHA_01874 4.8e-32
HHCIPGHA_01875 2.1e-30
HHCIPGHA_01876 4.7e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HHCIPGHA_01877 5.9e-158 S Protein of unknown function (DUF979)
HHCIPGHA_01878 2.3e-114 S Protein of unknown function (DUF969)
HHCIPGHA_01879 9.8e-232 G PTS system sugar-specific permease component
HHCIPGHA_01880 3.7e-93 S Protein of unknown function (DUF1440)
HHCIPGHA_01881 2.9e-103 S CAAX protease self-immunity
HHCIPGHA_01882 8.7e-196 S DUF218 domain
HHCIPGHA_01883 0.0 macB_3 V ABC transporter, ATP-binding protein
HHCIPGHA_01884 1.9e-269 cydA 1.10.3.14 C ubiquinol oxidase
HHCIPGHA_01885 1.7e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HHCIPGHA_01886 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HHCIPGHA_01887 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HHCIPGHA_01888 3.5e-174 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HHCIPGHA_01889 1.9e-167 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HHCIPGHA_01890 2.6e-197 tcsA S ABC transporter substrate-binding protein PnrA-like
HHCIPGHA_01891 9e-172 fpaP 3.4.11.5 I Releases the N-terminal proline from various substrates
HHCIPGHA_01892 2e-176 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
HHCIPGHA_01893 2e-99 G PTS system sorbose-specific iic component
HHCIPGHA_01894 7.7e-120 G PTS system mannose/fructose/sorbose family IID component
HHCIPGHA_01895 5.1e-52 2.7.1.191 G PTS system sorbose subfamily IIB component
HHCIPGHA_01896 1.6e-87 blaA6 V Beta-lactamase
HHCIPGHA_01897 9.7e-189 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HHCIPGHA_01898 2.5e-127 3.5.2.6 V Beta-lactamase enzyme family
HHCIPGHA_01899 6.1e-152 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HHCIPGHA_01900 4.2e-133 S membrane transporter protein
HHCIPGHA_01901 2.2e-27 G PTS system fructose IIA component
HHCIPGHA_01902 7e-123 G PTS system mannose/fructose/sorbose family IID component
HHCIPGHA_01903 1.7e-92 agaC G PTS system sorbose-specific iic component
HHCIPGHA_01904 1.3e-149 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
HHCIPGHA_01906 3.5e-16 S PD-(D/E)XK nuclease family transposase
HHCIPGHA_01907 1.5e-129 yeaE S Aldo/keto reductase family
HHCIPGHA_01908 5.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHCIPGHA_01909 1.7e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HHCIPGHA_01910 8.2e-125 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HHCIPGHA_01911 4.2e-100 GK ROK family
HHCIPGHA_01912 1.8e-125 uhpT EGP Major facilitator Superfamily
HHCIPGHA_01913 3.1e-199 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HHCIPGHA_01914 1.9e-162 EGP Major facilitator Superfamily
HHCIPGHA_01915 5.6e-64 rhaR K helix_turn_helix, arabinose operon control protein
HHCIPGHA_01916 5e-237 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HHCIPGHA_01917 3e-232 pbuG S permease
HHCIPGHA_01919 1.3e-88 K helix_turn_helix, mercury resistance
HHCIPGHA_01920 2.2e-230 pbuG S permease
HHCIPGHA_01921 4.9e-45 I bis(5'-adenosyl)-triphosphatase activity
HHCIPGHA_01922 2e-226 pbuG S permease
HHCIPGHA_01923 1.3e-27 K Bacteriophage CI repressor helix-turn-helix domain
HHCIPGHA_01924 7e-66 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HHCIPGHA_01925 7.7e-175 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHCIPGHA_01926 2e-221 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HHCIPGHA_01927 8.2e-78 scrR K Periplasmic binding protein domain
HHCIPGHA_01928 2e-84
HHCIPGHA_01929 1.5e-61
HHCIPGHA_01930 6e-32 L COG2963 Transposase and inactivated derivatives
HHCIPGHA_01931 6.4e-58 E amino acid
HHCIPGHA_01932 2e-169 K LysR substrate binding domain
HHCIPGHA_01933 0.0 1.3.5.4 C FAD binding domain
HHCIPGHA_01934 2.8e-241 brnQ U Component of the transport system for branched-chain amino acids
HHCIPGHA_01935 5.7e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HHCIPGHA_01936 6e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HHCIPGHA_01937 6.7e-86 S Peptidase propeptide and YPEB domain
HHCIPGHA_01938 6.9e-186 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HHCIPGHA_01939 7.1e-107 yhjX_2 P Major Facilitator Superfamily
HHCIPGHA_01940 2.7e-232 yhjX_2 P Major Facilitator Superfamily
HHCIPGHA_01941 2e-163 arbZ I Phosphate acyltransferases
HHCIPGHA_01942 3.6e-182 arbY M Glycosyl transferase family 8
HHCIPGHA_01943 3.9e-181 arbY M Glycosyl transferase family 8
HHCIPGHA_01944 1.8e-153 arbx M Glycosyl transferase family 8
HHCIPGHA_01945 3.7e-145 arbV 2.3.1.51 I Acyl-transferase
HHCIPGHA_01948 1.2e-129 K response regulator
HHCIPGHA_01949 0.0 vicK 2.7.13.3 T Histidine kinase
HHCIPGHA_01950 2e-252 yycH S YycH protein
HHCIPGHA_01951 6.9e-142 yycI S YycH protein
HHCIPGHA_01952 3.3e-149 vicX 3.1.26.11 S domain protein
HHCIPGHA_01953 5.4e-183 htrA 3.4.21.107 O serine protease
HHCIPGHA_01954 9.5e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHCIPGHA_01955 1.2e-107 P Cobalt transport protein
HHCIPGHA_01956 9.7e-250 cbiO1 S ABC transporter, ATP-binding protein
HHCIPGHA_01957 1.1e-93 S ABC-type cobalt transport system, permease component
HHCIPGHA_01958 8.3e-168 K helix_turn_helix, arabinose operon control protein
HHCIPGHA_01959 1.3e-146 htpX O Belongs to the peptidase M48B family
HHCIPGHA_01960 2.2e-91 lemA S LemA family
HHCIPGHA_01961 1.6e-181 ybiR P Citrate transporter
HHCIPGHA_01962 5.1e-69 S Iron-sulphur cluster biosynthesis
HHCIPGHA_01963 1.7e-16
HHCIPGHA_01964 3.8e-151
HHCIPGHA_01966 1.5e-244 ydaM M Glycosyl transferase
HHCIPGHA_01967 1.2e-208 G Glycosyl hydrolases family 8
HHCIPGHA_01968 4.5e-120 yfbR S HD containing hydrolase-like enzyme
HHCIPGHA_01969 1.1e-161 L HNH nucleases
HHCIPGHA_01970 9.6e-138 glnQ E ABC transporter, ATP-binding protein
HHCIPGHA_01971 4.8e-280 glnP P ABC transporter permease
HHCIPGHA_01972 8e-106 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HHCIPGHA_01973 1.5e-64 yeaO S Protein of unknown function, DUF488
HHCIPGHA_01974 1.6e-127 terC P Integral membrane protein TerC family
HHCIPGHA_01975 5.9e-94 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HHCIPGHA_01976 2.3e-133 cobB K SIR2 family
HHCIPGHA_01977 2e-80
HHCIPGHA_01978 2.4e-272 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHCIPGHA_01979 2.1e-100 yugP S Putative neutral zinc metallopeptidase
HHCIPGHA_01980 3.1e-175 S Alpha/beta hydrolase of unknown function (DUF915)
HHCIPGHA_01981 2.6e-143 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHCIPGHA_01982 8.4e-163 ypuA S Protein of unknown function (DUF1002)
HHCIPGHA_01983 6.5e-148 epsV 2.7.8.12 S glycosyl transferase family 2
HHCIPGHA_01984 1.2e-123 S Alpha/beta hydrolase family
HHCIPGHA_01985 1.4e-62
HHCIPGHA_01986 1.5e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHCIPGHA_01987 4.4e-15 S CAAX protease self-immunity
HHCIPGHA_01988 8.4e-131 S CAAX protease self-immunity
HHCIPGHA_01989 2.3e-26 S CAAX protease self-immunity
HHCIPGHA_01990 4.5e-239 cycA E Amino acid permease
HHCIPGHA_01991 2.9e-114 luxT K Bacterial regulatory proteins, tetR family
HHCIPGHA_01992 5.6e-139
HHCIPGHA_01993 3e-284 S Cysteine-rich secretory protein family
HHCIPGHA_01994 6.9e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HHCIPGHA_01995 5.2e-93
HHCIPGHA_01996 2.4e-268 yjcE P Sodium proton antiporter
HHCIPGHA_01997 2.2e-183 yibE S overlaps another CDS with the same product name
HHCIPGHA_01998 4.9e-118 yibF S overlaps another CDS with the same product name
HHCIPGHA_01999 1.1e-155 I alpha/beta hydrolase fold
HHCIPGHA_02000 0.0 G Belongs to the glycosyl hydrolase 31 family
HHCIPGHA_02001 2.2e-128 XK27_08435 K UTRA
HHCIPGHA_02002 1.6e-216 agaS G SIS domain
HHCIPGHA_02003 5.2e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHCIPGHA_02004 4.3e-83 2.7.1.191 G PTS system sorbose subfamily IIB component
HHCIPGHA_02005 2.9e-141 XK27_08455 G PTS system sorbose-specific iic component
HHCIPGHA_02006 1.6e-146 manZ_1 G PTS system mannose/fructose/sorbose family IID component
HHCIPGHA_02007 9.3e-68 2.7.1.191 G PTS system fructose IIA component
HHCIPGHA_02008 5.6e-16 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HHCIPGHA_02009 1.4e-201 S zinc-ribbon domain
HHCIPGHA_02010 6e-32 L COG2963 Transposase and inactivated derivatives

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)