ORF_ID e_value Gene_name EC_number CAZy COGs Description
KKDGPOJN_00001 2.3e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KKDGPOJN_00002 3.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KKDGPOJN_00003 2.4e-33 yaaA S S4 domain
KKDGPOJN_00004 7e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KKDGPOJN_00005 8.1e-38 yaaB S Domain of unknown function (DUF370)
KKDGPOJN_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KKDGPOJN_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KKDGPOJN_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
KKDGPOJN_00011 6.7e-184 yaaC S YaaC-like Protein
KKDGPOJN_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KKDGPOJN_00013 1.2e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KKDGPOJN_00014 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KKDGPOJN_00015 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KKDGPOJN_00016 2.8e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KKDGPOJN_00017 4e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KKDGPOJN_00018 1.3e-09
KKDGPOJN_00019 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KKDGPOJN_00020 5.5e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KKDGPOJN_00021 2.2e-211 yaaH M Glycoside Hydrolase Family
KKDGPOJN_00022 3.7e-99 yaaI Q COG1335 Amidases related to nicotinamidase
KKDGPOJN_00023 1.3e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KKDGPOJN_00024 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KKDGPOJN_00025 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KKDGPOJN_00026 5.1e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KKDGPOJN_00027 3.6e-32 yaaL S Protein of unknown function (DUF2508)
KKDGPOJN_00028 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
KKDGPOJN_00029 3.4e-39 S COG NOG14552 non supervised orthologous group
KKDGPOJN_00032 2.2e-30 csfB S Inhibitor of sigma-G Gin
KKDGPOJN_00033 2.5e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KKDGPOJN_00034 4.6e-189 yaaN P Belongs to the TelA family
KKDGPOJN_00035 2.6e-269 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KKDGPOJN_00036 4.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KKDGPOJN_00037 7.5e-55 yaaQ S protein conserved in bacteria
KKDGPOJN_00038 1.2e-71 yaaR S protein conserved in bacteria
KKDGPOJN_00039 1.3e-182 holB 2.7.7.7 L DNA polymerase III
KKDGPOJN_00040 4.4e-144 yaaT S stage 0 sporulation protein
KKDGPOJN_00041 7.7e-37 yabA L Involved in initiation control of chromosome replication
KKDGPOJN_00042 1.2e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
KKDGPOJN_00043 1.1e-47 yazA L endonuclease containing a URI domain
KKDGPOJN_00044 7.6e-163 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KKDGPOJN_00045 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
KKDGPOJN_00046 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KKDGPOJN_00047 1.1e-141 tatD L hydrolase, TatD
KKDGPOJN_00048 7e-232 rpfB GH23 T protein conserved in bacteria
KKDGPOJN_00049 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KKDGPOJN_00050 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KKDGPOJN_00051 8.4e-146 yabG S peptidase
KKDGPOJN_00052 7.8e-39 veg S protein conserved in bacteria
KKDGPOJN_00053 2.9e-27 sspF S DNA topological change
KKDGPOJN_00054 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KKDGPOJN_00055 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KKDGPOJN_00056 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KKDGPOJN_00057 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KKDGPOJN_00058 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KKDGPOJN_00059 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KKDGPOJN_00060 1.7e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KKDGPOJN_00061 1.2e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KKDGPOJN_00062 3.7e-40 yabK S Peptide ABC transporter permease
KKDGPOJN_00063 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KKDGPOJN_00064 6.2e-91 spoVT K stage V sporulation protein
KKDGPOJN_00065 5.4e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KKDGPOJN_00066 1.9e-275 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KKDGPOJN_00067 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KKDGPOJN_00068 1.9e-49 yabP S Sporulation protein YabP
KKDGPOJN_00069 2.4e-102 yabQ S spore cortex biosynthesis protein
KKDGPOJN_00070 2.3e-52 divIC D Septum formation initiator
KKDGPOJN_00071 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KKDGPOJN_00074 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KKDGPOJN_00075 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
KKDGPOJN_00076 1.1e-184 KLT serine threonine protein kinase
KKDGPOJN_00077 2.5e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KKDGPOJN_00078 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KKDGPOJN_00079 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KKDGPOJN_00080 1.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KKDGPOJN_00081 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KKDGPOJN_00082 4.5e-155 yacD 5.2.1.8 O peptidyl-prolyl isomerase
KKDGPOJN_00083 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KKDGPOJN_00084 1.2e-269 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KKDGPOJN_00085 2.3e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KKDGPOJN_00086 1.2e-160 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
KKDGPOJN_00087 6.7e-156 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KKDGPOJN_00088 7e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KKDGPOJN_00089 2.2e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KKDGPOJN_00090 4.5e-29 yazB K transcriptional
KKDGPOJN_00091 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KKDGPOJN_00092 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KKDGPOJN_00093 3.4e-39 S COG NOG14552 non supervised orthologous group
KKDGPOJN_00095 1.3e-07
KKDGPOJN_00098 2e-08
KKDGPOJN_00103 3.4e-39 S COG NOG14552 non supervised orthologous group
KKDGPOJN_00104 7.5e-77 ctsR K Belongs to the CtsR family
KKDGPOJN_00105 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KKDGPOJN_00106 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KKDGPOJN_00107 0.0 clpC O Belongs to the ClpA ClpB family
KKDGPOJN_00108 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KKDGPOJN_00109 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KKDGPOJN_00110 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KKDGPOJN_00111 2.1e-123 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KKDGPOJN_00112 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KKDGPOJN_00113 2e-277 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KKDGPOJN_00114 4.7e-117 cysE 2.3.1.30 E Serine acetyltransferase
KKDGPOJN_00115 6.2e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KKDGPOJN_00116 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KKDGPOJN_00117 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KKDGPOJN_00118 4.2e-89 yacP S RNA-binding protein containing a PIN domain
KKDGPOJN_00119 8.9e-116 sigH K Belongs to the sigma-70 factor family
KKDGPOJN_00120 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KKDGPOJN_00121 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
KKDGPOJN_00122 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KKDGPOJN_00123 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KKDGPOJN_00124 2.5e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KKDGPOJN_00125 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KKDGPOJN_00126 1.2e-106 rsmC 2.1.1.172 J Methyltransferase
KKDGPOJN_00127 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KKDGPOJN_00128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KKDGPOJN_00129 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
KKDGPOJN_00130 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KKDGPOJN_00131 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KKDGPOJN_00132 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KKDGPOJN_00133 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KKDGPOJN_00134 9.2e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
KKDGPOJN_00135 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KKDGPOJN_00136 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KKDGPOJN_00137 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
KKDGPOJN_00138 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KKDGPOJN_00139 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KKDGPOJN_00140 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KKDGPOJN_00141 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KKDGPOJN_00142 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KKDGPOJN_00143 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KKDGPOJN_00144 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KKDGPOJN_00145 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KKDGPOJN_00146 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KKDGPOJN_00147 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KKDGPOJN_00148 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KKDGPOJN_00149 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KKDGPOJN_00150 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KKDGPOJN_00151 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KKDGPOJN_00152 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KKDGPOJN_00153 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KKDGPOJN_00154 1.9e-23 rpmD J Ribosomal protein L30
KKDGPOJN_00155 4.1e-72 rplO J binds to the 23S rRNA
KKDGPOJN_00156 1.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KKDGPOJN_00157 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KKDGPOJN_00158 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
KKDGPOJN_00159 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KKDGPOJN_00160 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KKDGPOJN_00161 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KKDGPOJN_00162 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KKDGPOJN_00163 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KKDGPOJN_00164 4.7e-58 rplQ J Ribosomal protein L17
KKDGPOJN_00165 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KKDGPOJN_00166 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KKDGPOJN_00167 1.3e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KKDGPOJN_00168 1.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KKDGPOJN_00169 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KKDGPOJN_00170 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KKDGPOJN_00171 1.2e-143 ybaJ Q Methyltransferase domain
KKDGPOJN_00172 3.6e-82 yizA S Damage-inducible protein DinB
KKDGPOJN_00173 4.5e-79 ybaK S Protein of unknown function (DUF2521)
KKDGPOJN_00174 7.9e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KKDGPOJN_00175 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KKDGPOJN_00176 1.7e-75 gerD
KKDGPOJN_00177 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KKDGPOJN_00178 2.5e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
KKDGPOJN_00179 3.4e-39 S COG NOG14552 non supervised orthologous group
KKDGPOJN_00182 1.6e-08
KKDGPOJN_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
KKDGPOJN_00186 2.5e-217 glcP G Major Facilitator Superfamily
KKDGPOJN_00187 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KKDGPOJN_00188 2e-180 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
KKDGPOJN_00189 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
KKDGPOJN_00190 6e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
KKDGPOJN_00191 2.2e-174 ybaS 1.1.1.58 S Na -dependent transporter
KKDGPOJN_00192 2.4e-112 ybbA S Putative esterase
KKDGPOJN_00193 2.3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKDGPOJN_00194 6.9e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKDGPOJN_00195 2e-172 feuA P Iron-uptake system-binding protein
KKDGPOJN_00196 7e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
KKDGPOJN_00197 1.3e-237 ybbC 3.2.1.52 S protein conserved in bacteria
KKDGPOJN_00198 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KKDGPOJN_00199 3.1e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
KKDGPOJN_00200 2.9e-238 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KKDGPOJN_00201 3.1e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KKDGPOJN_00202 9.1e-86 ybbJ J acetyltransferase
KKDGPOJN_00203 2.8e-76 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
KKDGPOJN_00209 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KKDGPOJN_00210 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KKDGPOJN_00211 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KKDGPOJN_00212 6.1e-226 ybbR S protein conserved in bacteria
KKDGPOJN_00213 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KKDGPOJN_00214 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KKDGPOJN_00215 3.2e-153 V ATPases associated with a variety of cellular activities
KKDGPOJN_00216 3.8e-106 S ABC-2 family transporter protein
KKDGPOJN_00217 4e-98 ybdN
KKDGPOJN_00218 1.1e-132 ybdO S Domain of unknown function (DUF4885)
KKDGPOJN_00219 2.8e-162 dkgB S Aldo/keto reductase family
KKDGPOJN_00220 5e-93 yxaC M effector of murein hydrolase
KKDGPOJN_00221 6.9e-52 S LrgA family
KKDGPOJN_00222 2.2e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
KKDGPOJN_00224 4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KKDGPOJN_00225 9.4e-95 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KKDGPOJN_00226 1.8e-201 T COG4585 Signal transduction histidine kinase
KKDGPOJN_00227 1.8e-108 KT LuxR family transcriptional regulator
KKDGPOJN_00228 9.2e-167 V COG1131 ABC-type multidrug transport system, ATPase component
KKDGPOJN_00229 5.2e-207 V COG0842 ABC-type multidrug transport system, permease component
KKDGPOJN_00230 1.6e-197 V ABC-2 family transporter protein
KKDGPOJN_00231 5.8e-25
KKDGPOJN_00232 4.5e-77 S Domain of unknown function (DUF4879)
KKDGPOJN_00233 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
KKDGPOJN_00234 4.7e-107 yqeB
KKDGPOJN_00235 9.2e-40 ybyB
KKDGPOJN_00236 9.5e-292 ybeC E amino acid
KKDGPOJN_00238 6e-42 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KKDGPOJN_00239 4e-53
KKDGPOJN_00240 2.6e-15 S Protein of unknown function (DUF2651)
KKDGPOJN_00241 9.7e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KKDGPOJN_00242 1.7e-259 glpT G -transporter
KKDGPOJN_00243 1.3e-16 S Protein of unknown function (DUF2651)
KKDGPOJN_00244 5e-212 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
KKDGPOJN_00246 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
KKDGPOJN_00247 3.5e-31
KKDGPOJN_00248 1.2e-82 K Helix-turn-helix XRE-family like proteins
KKDGPOJN_00249 8.6e-201 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KKDGPOJN_00250 4.4e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KKDGPOJN_00251 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KKDGPOJN_00252 2.5e-86 ybfM S SNARE associated Golgi protein
KKDGPOJN_00253 5.6e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KKDGPOJN_00254 1e-41 ybfN
KKDGPOJN_00255 1.9e-191 yceA S Belongs to the UPF0176 family
KKDGPOJN_00256 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KKDGPOJN_00257 1.9e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KKDGPOJN_00258 6.8e-257 mmuP E amino acid
KKDGPOJN_00259 5.1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
KKDGPOJN_00260 3.9e-257 agcS E Sodium alanine symporter
KKDGPOJN_00261 5.3e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
KKDGPOJN_00262 1.7e-211 phoQ 2.7.13.3 T Histidine kinase
KKDGPOJN_00263 1.9e-172 glnL T Regulator
KKDGPOJN_00264 4.6e-126 ycbJ S Macrolide 2'-phosphotransferase
KKDGPOJN_00265 1.8e-25 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
KKDGPOJN_00266 5.6e-62 ycbP S Protein of unknown function (DUF2512)
KKDGPOJN_00267 5.3e-77 sleB 3.5.1.28 M Cell wall
KKDGPOJN_00268 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
KKDGPOJN_00269 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KKDGPOJN_00270 4e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KKDGPOJN_00271 3.2e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KKDGPOJN_00272 4.5e-208 ycbU E Selenocysteine lyase
KKDGPOJN_00273 1e-241 lmrB EGP the major facilitator superfamily
KKDGPOJN_00274 5.9e-100 yxaF K Transcriptional regulator
KKDGPOJN_00275 1.9e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KKDGPOJN_00276 1.1e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KKDGPOJN_00277 8.6e-193 yccF K DNA-templated transcriptional preinitiation complex assembly
KKDGPOJN_00278 9.5e-172 yccK C Aldo keto reductase
KKDGPOJN_00279 1e-171 ycdA S Domain of unknown function (DUF5105)
KKDGPOJN_00280 7.2e-248 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
KKDGPOJN_00281 7.7e-263 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
KKDGPOJN_00282 2.9e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
KKDGPOJN_00283 1.9e-187 S response regulator aspartate phosphatase
KKDGPOJN_00284 5.2e-139 IQ Enoyl-(Acyl carrier protein) reductase
KKDGPOJN_00285 3.8e-35 EGP Major facilitator Superfamily
KKDGPOJN_00286 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KKDGPOJN_00287 1e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
KKDGPOJN_00288 7.2e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KKDGPOJN_00289 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KKDGPOJN_00290 1.4e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKDGPOJN_00291 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
KKDGPOJN_00292 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
KKDGPOJN_00293 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
KKDGPOJN_00294 9.7e-138 terC P Protein of unknown function (DUF475)
KKDGPOJN_00295 0.0 yceG S Putative component of 'biosynthetic module'
KKDGPOJN_00296 2.3e-193 yceH P Belongs to the TelA family
KKDGPOJN_00297 5.3e-215 naiP P Uncharacterised MFS-type transporter YbfB
KKDGPOJN_00298 3.9e-229 proV 3.6.3.32 E glycine betaine
KKDGPOJN_00299 1.6e-138 opuAB P glycine betaine
KKDGPOJN_00300 2e-163 opuAC E glycine betaine
KKDGPOJN_00301 7.3e-211 amhX S amidohydrolase
KKDGPOJN_00302 5.8e-229 ycgA S Membrane
KKDGPOJN_00303 2e-80 ycgB
KKDGPOJN_00304 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
KKDGPOJN_00305 3.7e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KKDGPOJN_00306 4e-260 mdr EGP Major facilitator Superfamily
KKDGPOJN_00307 1.8e-75 emrR K helix_turn_helix multiple antibiotic resistance protein
KKDGPOJN_00308 4.7e-114 ycgF E Lysine exporter protein LysE YggA
KKDGPOJN_00309 1.2e-148 yqcI S YqcI/YcgG family
KKDGPOJN_00310 1.2e-244 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KKDGPOJN_00311 1.3e-113 ycgI S Domain of unknown function (DUF1989)
KKDGPOJN_00312 1.8e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KKDGPOJN_00314 6.2e-108 tmrB S AAA domain
KKDGPOJN_00315 6.9e-147 4.2.1.118 G Xylose isomerase-like TIM barrel
KKDGPOJN_00316 3.1e-221 G COG0477 Permeases of the major facilitator superfamily
KKDGPOJN_00317 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KKDGPOJN_00318 1.3e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KKDGPOJN_00319 1.5e-146 ycgL S Predicted nucleotidyltransferase
KKDGPOJN_00320 2.3e-170 ycgM E Proline dehydrogenase
KKDGPOJN_00321 2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KKDGPOJN_00322 5.8e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKDGPOJN_00323 3.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
KKDGPOJN_00324 1.6e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KKDGPOJN_00325 8.1e-279 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KKDGPOJN_00326 6e-57 nirD 1.7.1.15 P Nitrite reductase
KKDGPOJN_00327 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KKDGPOJN_00328 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KKDGPOJN_00329 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
KKDGPOJN_00330 2.4e-223 nasA P COG2223 Nitrate nitrite transporter
KKDGPOJN_00331 7.1e-228 yciC S GTPases (G3E family)
KKDGPOJN_00332 3e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KKDGPOJN_00333 1.1e-72 yckC S membrane
KKDGPOJN_00334 2.2e-51 S Protein of unknown function (DUF2680)
KKDGPOJN_00335 7.3e-296 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKDGPOJN_00336 2.9e-69 nin S Competence protein J (ComJ)
KKDGPOJN_00337 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
KKDGPOJN_00338 6.2e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
KKDGPOJN_00339 2.8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
KKDGPOJN_00340 6.3e-63 hxlR K transcriptional
KKDGPOJN_00341 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKDGPOJN_00342 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKDGPOJN_00343 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
KKDGPOJN_00344 8.3e-139 srfAD Q thioesterase
KKDGPOJN_00345 2.7e-249 bamJ E Aminotransferase class I and II
KKDGPOJN_00346 1.5e-129 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
KKDGPOJN_00347 4.5e-109 yczE S membrane
KKDGPOJN_00348 1.5e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KKDGPOJN_00349 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
KKDGPOJN_00350 1.4e-142 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KKDGPOJN_00351 1.9e-158 bsdA K LysR substrate binding domain
KKDGPOJN_00352 2.7e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KKDGPOJN_00353 6.3e-284 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KKDGPOJN_00354 5.8e-38 bsdD 4.1.1.61 S response to toxic substance
KKDGPOJN_00355 9.8e-77 yclD
KKDGPOJN_00356 3.2e-270 dtpT E amino acid peptide transporter
KKDGPOJN_00357 4e-280 yclG M Pectate lyase superfamily protein
KKDGPOJN_00359 4.1e-295 gerKA EG Spore germination protein
KKDGPOJN_00360 1.6e-235 gerKC S spore germination
KKDGPOJN_00361 5.1e-196 gerKB F Spore germination protein
KKDGPOJN_00362 1.7e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKDGPOJN_00363 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KKDGPOJN_00364 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
KKDGPOJN_00365 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
KKDGPOJN_00366 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
KKDGPOJN_00367 1.3e-218 yxeP 3.5.1.47 E hydrolase activity
KKDGPOJN_00368 3.2e-253 yxeQ S MmgE/PrpD family
KKDGPOJN_00369 1.1e-121 yclH P ABC transporter
KKDGPOJN_00370 1.1e-222 yclI V ABC transporter (permease) YclI
KKDGPOJN_00371 2.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKDGPOJN_00372 1.1e-259 T PhoQ Sensor
KKDGPOJN_00373 1.6e-80 S aspartate phosphatase
KKDGPOJN_00375 6.1e-252 lysC 2.7.2.4 E Belongs to the aspartokinase family
KKDGPOJN_00376 6.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKDGPOJN_00377 1.1e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKDGPOJN_00378 3.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KKDGPOJN_00379 1.2e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KKDGPOJN_00380 6.6e-249 ycnB EGP Major facilitator Superfamily
KKDGPOJN_00381 1.2e-152 ycnC K Transcriptional regulator
KKDGPOJN_00382 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
KKDGPOJN_00383 1e-44 ycnE S Monooxygenase
KKDGPOJN_00384 8.8e-53 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
KKDGPOJN_00385 5.9e-266 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KKDGPOJN_00386 3.8e-219 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KKDGPOJN_00387 5.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KKDGPOJN_00388 3.6e-149 glcU U Glucose uptake
KKDGPOJN_00389 3.2e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKDGPOJN_00390 1.3e-95 ycnI S protein conserved in bacteria
KKDGPOJN_00391 1.8e-298 ycnJ P protein, homolog of Cu resistance protein CopC
KKDGPOJN_00392 2.5e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
KKDGPOJN_00393 2e-55
KKDGPOJN_00394 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
KKDGPOJN_00395 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KKDGPOJN_00396 2.2e-207 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
KKDGPOJN_00397 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KKDGPOJN_00399 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KKDGPOJN_00400 6e-140 ycsF S Belongs to the UPF0271 (lamB) family
KKDGPOJN_00401 3.9e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
KKDGPOJN_00402 3.3e-149 ycsI S Belongs to the D-glutamate cyclase family
KKDGPOJN_00403 1.7e-136 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
KKDGPOJN_00404 9.3e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KKDGPOJN_00405 1.7e-129 kipR K Transcriptional regulator
KKDGPOJN_00406 2.7e-117 ycsK E anatomical structure formation involved in morphogenesis
KKDGPOJN_00408 5.1e-56 yczJ S biosynthesis
KKDGPOJN_00409 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KKDGPOJN_00410 3.4e-174 ydhF S Oxidoreductase
KKDGPOJN_00411 0.0 mtlR K transcriptional regulator, MtlR
KKDGPOJN_00412 2.7e-285 ydaB IQ acyl-CoA ligase
KKDGPOJN_00413 9.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKDGPOJN_00414 5.6e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
KKDGPOJN_00415 2.3e-113 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KKDGPOJN_00416 3.1e-77 ydaG 1.4.3.5 S general stress protein
KKDGPOJN_00417 4.6e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KKDGPOJN_00418 2.7e-48 ydzA EGP Major facilitator Superfamily
KKDGPOJN_00419 4.3e-74 lrpC K Transcriptional regulator
KKDGPOJN_00420 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KKDGPOJN_00421 8.6e-193 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
KKDGPOJN_00422 7.4e-147 ydaK T Diguanylate cyclase, GGDEF domain
KKDGPOJN_00423 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
KKDGPOJN_00424 4.2e-231 ydaM M Glycosyl transferase family group 2
KKDGPOJN_00425 0.0 ydaN S Bacterial cellulose synthase subunit
KKDGPOJN_00426 0.0 ydaO E amino acid
KKDGPOJN_00427 1.2e-74 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KKDGPOJN_00428 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KKDGPOJN_00429 5.3e-48 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KKDGPOJN_00430 5.9e-68
KKDGPOJN_00432 8.8e-119 S Histidine kinase
KKDGPOJN_00433 8.1e-42 S Histidine kinase
KKDGPOJN_00435 9.4e-12
KKDGPOJN_00437 6.9e-77
KKDGPOJN_00438 2.1e-39
KKDGPOJN_00439 2e-225 mntH P H( )-stimulated, divalent metal cation uptake system
KKDGPOJN_00442 6.5e-34 ydaT
KKDGPOJN_00443 2.9e-72 yvaD S Family of unknown function (DUF5360)
KKDGPOJN_00444 7e-54 yvaE P Small Multidrug Resistance protein
KKDGPOJN_00445 4e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
KKDGPOJN_00447 1.9e-56 ydbB G Cupin domain
KKDGPOJN_00448 4.2e-59 ydbC S Domain of unknown function (DUF4937
KKDGPOJN_00449 1.4e-155 ydbD P Catalase
KKDGPOJN_00450 3.2e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KKDGPOJN_00451 1.2e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KKDGPOJN_00452 1.1e-118 dctR T COG4565 Response regulator of citrate malate metabolism
KKDGPOJN_00453 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KKDGPOJN_00454 3.2e-160 ydbI S AI-2E family transporter
KKDGPOJN_00455 1.9e-172 ydbJ V ABC transporter, ATP-binding protein
KKDGPOJN_00456 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KKDGPOJN_00457 2.1e-52 ydbL
KKDGPOJN_00458 7.5e-203 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KKDGPOJN_00459 1.5e-10 S Fur-regulated basic protein B
KKDGPOJN_00460 5.8e-09 S Fur-regulated basic protein A
KKDGPOJN_00461 8.1e-120 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KKDGPOJN_00462 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KKDGPOJN_00463 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KKDGPOJN_00464 4.8e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KKDGPOJN_00465 2.9e-247 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KKDGPOJN_00466 1.3e-60 ydbS S Bacterial PH domain
KKDGPOJN_00467 1.7e-263 ydbT S Membrane
KKDGPOJN_00468 3.1e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KKDGPOJN_00469 6.8e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KKDGPOJN_00470 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KKDGPOJN_00471 6.9e-220 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KKDGPOJN_00472 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KKDGPOJN_00473 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KKDGPOJN_00474 6.1e-146 rsbR T Positive regulator of sigma-B
KKDGPOJN_00475 6.8e-57 rsbS T antagonist
KKDGPOJN_00476 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KKDGPOJN_00477 1.7e-187 rsbU 3.1.3.3 KT phosphatase
KKDGPOJN_00478 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
KKDGPOJN_00479 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KKDGPOJN_00480 1.5e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKDGPOJN_00481 2.4e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KKDGPOJN_00482 0.0 yhgF K COG2183 Transcriptional accessory protein
KKDGPOJN_00483 1.7e-14
KKDGPOJN_00484 1.9e-58 ydcK S Belongs to the SprT family
KKDGPOJN_00492 1.1e-95 ywrO S Flavodoxin-like fold
KKDGPOJN_00493 1.1e-227 proP EGP Transporter
KKDGPOJN_00494 1.9e-83 S Domain of unknown function with cystatin-like fold (DUF4467)
KKDGPOJN_00495 2.7e-73 maoC I N-terminal half of MaoC dehydratase
KKDGPOJN_00496 3.2e-64 yyaQ S YjbR
KKDGPOJN_00497 1.8e-66 ywnA K Transcriptional regulator
KKDGPOJN_00498 9.9e-112 ywnB S NAD(P)H-binding
KKDGPOJN_00499 1.4e-30 cspL K Cold shock
KKDGPOJN_00500 2e-77 carD K Transcription factor
KKDGPOJN_00501 4e-119 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KKDGPOJN_00502 1.1e-101 S Protein of unknown function (DUF2812)
KKDGPOJN_00503 9.8e-52 K Transcriptional regulator PadR-like family
KKDGPOJN_00504 3.8e-173 ybfA 3.4.15.5 K FR47-like protein
KKDGPOJN_00505 3.8e-235 ybfB G COG0477 Permeases of the major facilitator superfamily
KKDGPOJN_00506 1.1e-181 S Patatin-like phospholipase
KKDGPOJN_00507 6.3e-79 S DinB superfamily
KKDGPOJN_00508 5e-117 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
KKDGPOJN_00509 7.8e-67 K COG1802 Transcriptional regulators
KKDGPOJN_00510 6.6e-39 yabJ 3.5.99.10 J Endoribonuclease L-PSP
KKDGPOJN_00511 1.9e-141 sdaC E Serine transporter
KKDGPOJN_00512 5.3e-164 E Peptidase dimerisation domain
KKDGPOJN_00513 1.7e-125 rhaS5 K helix_turn_helix, arabinose operon control protein
KKDGPOJN_00514 5.9e-177 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KKDGPOJN_00515 1e-233 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KKDGPOJN_00516 6.1e-193 ydeG EGP Major facilitator superfamily
KKDGPOJN_00517 2e-52 3.6.1.55 F Belongs to the Nudix hydrolase family
KKDGPOJN_00520 4.6e-268 ygaK C COG0277 FAD FMN-containing dehydrogenases
KKDGPOJN_00521 5e-168 czcD P COG1230 Co Zn Cd efflux system component
KKDGPOJN_00522 9.2e-200 trkA P Oxidoreductase
KKDGPOJN_00525 3.6e-14 ykkA S Protein of unknown function (DUF664)
KKDGPOJN_00526 8.7e-55 ydeH
KKDGPOJN_00527 1.4e-192 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KKDGPOJN_00528 4.6e-148 Q ubiE/COQ5 methyltransferase family
KKDGPOJN_00529 1.3e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KKDGPOJN_00530 9.2e-231 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KKDGPOJN_00531 4.9e-163 S Sodium Bile acid symporter family
KKDGPOJN_00532 2.9e-201 adhA 1.1.1.1 C alcohol dehydrogenase
KKDGPOJN_00533 3.6e-67 yraB K helix_turn_helix, mercury resistance
KKDGPOJN_00534 2.8e-214 mleN_2 C antiporter
KKDGPOJN_00535 9.2e-264 K helix_turn_helix gluconate operon transcriptional repressor
KKDGPOJN_00536 4.6e-114 paiB K Transcriptional regulator
KKDGPOJN_00538 9.8e-171 ydeR EGP Major facilitator Superfamily
KKDGPOJN_00539 1.3e-102 ydeS K Transcriptional regulator
KKDGPOJN_00540 1.8e-156 ydeK EG -transporter
KKDGPOJN_00541 5.2e-267 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KKDGPOJN_00542 9.5e-49 yraD M Spore coat protein
KKDGPOJN_00543 5.1e-25 yraE
KKDGPOJN_00544 4.2e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KKDGPOJN_00545 2.9e-63 yraF M Spore coat protein
KKDGPOJN_00546 4.5e-36 yraG
KKDGPOJN_00547 1.1e-108 ybjJ G Major Facilitator Superfamily
KKDGPOJN_00548 1.7e-76 2.7.1.2 GK Transcriptional regulator
KKDGPOJN_00549 4.1e-24 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KKDGPOJN_00550 2.3e-216 ydfH 2.7.13.3 T Histidine kinase
KKDGPOJN_00551 8.3e-111 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KKDGPOJN_00552 0.0 ydfJ S drug exporters of the RND superfamily
KKDGPOJN_00553 1.2e-132 puuD S Peptidase C26
KKDGPOJN_00554 1.8e-298 expZ S ABC transporter
KKDGPOJN_00555 3.6e-99 ynaD J Acetyltransferase (GNAT) domain
KKDGPOJN_00556 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
KKDGPOJN_00557 2e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KKDGPOJN_00558 1.1e-209 tcaB EGP Major facilitator Superfamily
KKDGPOJN_00559 6.8e-226 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KKDGPOJN_00560 1.3e-156 K Helix-turn-helix XRE-family like proteins
KKDGPOJN_00561 8.5e-123 ydhB S membrane transporter protein
KKDGPOJN_00562 2.9e-81 bltD 2.3.1.57 K FR47-like protein
KKDGPOJN_00563 2.6e-149 bltR K helix_turn_helix, mercury resistance
KKDGPOJN_00564 6.9e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KKDGPOJN_00565 1.3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
KKDGPOJN_00566 1.7e-145 ycgJ_1 Q ubiE/COQ5 methyltransferase family
KKDGPOJN_00567 8e-167 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
KKDGPOJN_00568 5.3e-119 ydhC K FCD
KKDGPOJN_00569 8.3e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KKDGPOJN_00572 1.2e-260 pbpE V Beta-lactamase
KKDGPOJN_00574 1.2e-97 ydhK M Protein of unknown function (DUF1541)
KKDGPOJN_00575 1.2e-195 pbuE EGP Major facilitator Superfamily
KKDGPOJN_00576 5.1e-133 ydhQ K UTRA
KKDGPOJN_00577 4.9e-117 K FCD
KKDGPOJN_00578 1.4e-215 yeaN P COG2807 Cyanate permease
KKDGPOJN_00579 2.6e-49 sugE P Small Multidrug Resistance protein
KKDGPOJN_00580 2.3e-51 ykkC P Small Multidrug Resistance protein
KKDGPOJN_00581 5.3e-104 yvdT K Transcriptional regulator
KKDGPOJN_00582 1.2e-296 yveA E amino acid
KKDGPOJN_00583 8.7e-164 ydhU P Catalase
KKDGPOJN_00584 3.9e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
KKDGPOJN_00585 1.8e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
KKDGPOJN_00586 6.6e-249 iolT EGP Major facilitator Superfamily
KKDGPOJN_00589 3.4e-39 S COG NOG14552 non supervised orthologous group
KKDGPOJN_00590 7.8e-08
KKDGPOJN_00592 1.3e-182 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KKDGPOJN_00593 2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KKDGPOJN_00594 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KKDGPOJN_00595 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KKDGPOJN_00596 3e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KKDGPOJN_00597 0.0 ydiF S ABC transporter
KKDGPOJN_00598 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KKDGPOJN_00599 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KKDGPOJN_00600 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KKDGPOJN_00601 3.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KKDGPOJN_00602 1.7e-27 ydiK S Domain of unknown function (DUF4305)
KKDGPOJN_00603 4.3e-127 ydiL S CAAX protease self-immunity
KKDGPOJN_00604 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KKDGPOJN_00605 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KKDGPOJN_00606 1.5e-24 S Protein of unknown function (DUF4064)
KKDGPOJN_00607 0.0 K NB-ARC domain
KKDGPOJN_00608 8.8e-198 gutB 1.1.1.14 E Dehydrogenase
KKDGPOJN_00609 2.2e-249 gutA G MFS/sugar transport protein
KKDGPOJN_00610 9.8e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
KKDGPOJN_00611 3.3e-31 yjdJ S Domain of unknown function (DUF4306)
KKDGPOJN_00612 5.6e-113 pspA KT Phage shock protein A
KKDGPOJN_00613 6.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KKDGPOJN_00614 3.1e-120 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
KKDGPOJN_00615 3.5e-156 ydjI S virion core protein (lumpy skin disease virus)
KKDGPOJN_00616 0.0 yrhL I Acyltransferase family
KKDGPOJN_00617 1.4e-145 rsiV S Protein of unknown function (DUF3298)
KKDGPOJN_00618 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KKDGPOJN_00619 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KKDGPOJN_00620 4.2e-62 ydjM M Lytic transglycolase
KKDGPOJN_00621 2.7e-135 ydjN U Involved in the tonB-independent uptake of proteins
KKDGPOJN_00623 7.2e-35 ydjO S Cold-inducible protein YdjO
KKDGPOJN_00624 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KKDGPOJN_00625 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KKDGPOJN_00626 2.2e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KKDGPOJN_00627 3.5e-177 yeaC S COG0714 MoxR-like ATPases
KKDGPOJN_00628 3.5e-211 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KKDGPOJN_00629 0.0 yebA E COG1305 Transglutaminase-like enzymes
KKDGPOJN_00630 4.7e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KKDGPOJN_00631 1.3e-139 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
KKDGPOJN_00632 5.1e-117 F ATP-grasp domain
KKDGPOJN_00633 3.9e-106 pphA 5.4.2.9 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KKDGPOJN_00634 1.2e-134 aspC 2.6.1.1 E DegT/DnrJ/EryC1/StrS aminotransferase family
KKDGPOJN_00635 3.9e-149 yqjV G Major Facilitator Superfamily
KKDGPOJN_00636 1.3e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KKDGPOJN_00637 5.9e-245 S Domain of unknown function (DUF4179)
KKDGPOJN_00638 6.2e-209 pbuG S permease
KKDGPOJN_00639 2.8e-124 yebC M Membrane
KKDGPOJN_00641 3.4e-92 yebE S UPF0316 protein
KKDGPOJN_00642 6.1e-28 yebG S NETI protein
KKDGPOJN_00643 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KKDGPOJN_00644 1e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KKDGPOJN_00645 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KKDGPOJN_00646 8.2e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KKDGPOJN_00647 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KKDGPOJN_00648 7.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KKDGPOJN_00649 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KKDGPOJN_00650 1.1e-270 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KKDGPOJN_00651 1e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KKDGPOJN_00652 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KKDGPOJN_00653 5e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KKDGPOJN_00654 2e-233 purD 6.3.4.13 F Belongs to the GARS family
KKDGPOJN_00655 8.9e-26 S Protein of unknown function (DUF2892)
KKDGPOJN_00656 0.0 yerA 3.5.4.2 F adenine deaminase
KKDGPOJN_00657 4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
KKDGPOJN_00658 2.4e-50 yerC S protein conserved in bacteria
KKDGPOJN_00659 7.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
KKDGPOJN_00660 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KKDGPOJN_00661 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KKDGPOJN_00662 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KKDGPOJN_00663 2.6e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
KKDGPOJN_00664 3.8e-195 yerI S homoserine kinase type II (protein kinase fold)
KKDGPOJN_00665 1.3e-120 sapB S MgtC SapB transporter
KKDGPOJN_00666 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKDGPOJN_00667 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KKDGPOJN_00668 7.9e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KKDGPOJN_00669 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KKDGPOJN_00670 3.4e-152 yerO K Transcriptional regulator
KKDGPOJN_00671 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KKDGPOJN_00672 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KKDGPOJN_00673 3.8e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KKDGPOJN_00674 9.8e-85
KKDGPOJN_00675 7e-102 H Prokaryotic E2 family B
KKDGPOJN_00676 1.6e-27 S Prokaryotic homologs of the JAB domain
KKDGPOJN_00677 7.5e-78 V HNH nucleases
KKDGPOJN_00678 6.5e-160 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
KKDGPOJN_00679 4.6e-136 cylB V ABC-2 type transporter
KKDGPOJN_00680 1.4e-13 S Protein of unknown function, DUF600
KKDGPOJN_00681 4.1e-62 S Protein of unknown function, DUF600
KKDGPOJN_00682 1.3e-78 yobL L nucleic acid phosphodiester bond hydrolysis
KKDGPOJN_00683 8.7e-42 S Immunity protein 22
KKDGPOJN_00684 8.7e-31
KKDGPOJN_00685 5.8e-253 yobL S Bacterial EndoU nuclease
KKDGPOJN_00686 9.4e-127 yeeN K transcriptional regulatory protein
KKDGPOJN_00689 1.1e-108 aadK G Streptomycin adenylyltransferase
KKDGPOJN_00690 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
KKDGPOJN_00691 3.3e-45 cotJB S CotJB protein
KKDGPOJN_00692 8.9e-104 cotJC P Spore Coat
KKDGPOJN_00693 1e-93 yesJ K Acetyltransferase (GNAT) family
KKDGPOJN_00695 8.2e-120 yetF S membrane
KKDGPOJN_00696 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KKDGPOJN_00697 7.5e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KKDGPOJN_00698 4.1e-153 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KKDGPOJN_00699 2.9e-137 sbp P COG1613 ABC-type sulfate transport system, periplasmic component
KKDGPOJN_00700 7.6e-112 cysT O COG0555 ABC-type sulfate transport system, permease component
KKDGPOJN_00701 3.5e-104 cysW P COG4208 ABC-type sulfate transport system, permease component
KKDGPOJN_00702 8.5e-132 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KKDGPOJN_00703 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
KKDGPOJN_00704 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
KKDGPOJN_00705 8.2e-106 yetJ S Belongs to the BI1 family
KKDGPOJN_00706 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
KKDGPOJN_00707 2.4e-206 yetM CH FAD binding domain
KKDGPOJN_00708 7.5e-197 yetN S Protein of unknown function (DUF3900)
KKDGPOJN_00709 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KKDGPOJN_00711 2e-49 MA20_23570 K Winged helix DNA-binding domain
KKDGPOJN_00712 1.6e-163 V ATPases associated with a variety of cellular activities
KKDGPOJN_00713 3.7e-126 V ABC-2 type transporter
KKDGPOJN_00715 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KKDGPOJN_00716 7.9e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
KKDGPOJN_00717 2.4e-172 yfnG 4.2.1.45 M dehydratase
KKDGPOJN_00718 1.8e-178 yfnF M Nucleotide-diphospho-sugar transferase
KKDGPOJN_00719 3.9e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
KKDGPOJN_00720 2.4e-186 yfnD M Nucleotide-diphospho-sugar transferase
KKDGPOJN_00721 1e-218 fsr P COG0477 Permeases of the major facilitator superfamily
KKDGPOJN_00722 1.9e-245 yfnA E amino acid
KKDGPOJN_00723 2e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KKDGPOJN_00724 6e-104 yfmS NT chemotaxis protein
KKDGPOJN_00725 5.2e-167 IQ Enoyl-(Acyl carrier protein) reductase
KKDGPOJN_00726 3.2e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KKDGPOJN_00727 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KKDGPOJN_00728 1.8e-69 yfmP K transcriptional
KKDGPOJN_00729 2.1e-208 yfmO EGP Major facilitator Superfamily
KKDGPOJN_00730 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KKDGPOJN_00731 7.9e-205 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KKDGPOJN_00732 2e-66 yfmK 2.3.1.128 K acetyltransferase
KKDGPOJN_00733 6.1e-188 yfmJ S N-terminal domain of oxidoreductase
KKDGPOJN_00734 1.2e-24 S Protein of unknown function (DUF3212)
KKDGPOJN_00735 1.3e-57 yflT S Heat induced stress protein YflT
KKDGPOJN_00736 2.5e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
KKDGPOJN_00737 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
KKDGPOJN_00738 4.6e-28 Q PFAM Collagen triple helix
KKDGPOJN_00741 5.6e-23 M1-820 Q Collagen triple helix repeat (20 copies)
KKDGPOJN_00742 6.8e-24 M1-820 Q Collagen triple helix repeat (20 copies)
KKDGPOJN_00743 0.0 ywpD T PhoQ Sensor
KKDGPOJN_00744 3.7e-151 M1-574 T Transcriptional regulatory protein, C terminal
KKDGPOJN_00745 0.0 M1-568 M cell wall anchor domain
KKDGPOJN_00746 4.6e-80 srtA 3.4.22.70 M Sortase family
KKDGPOJN_00747 6.9e-271 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KKDGPOJN_00748 5.2e-119 citT T response regulator
KKDGPOJN_00749 1.6e-174 yflP S Tripartite tricarboxylate transporter family receptor
KKDGPOJN_00750 2.5e-226 citM C Citrate transporter
KKDGPOJN_00751 3.3e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KKDGPOJN_00752 7.1e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KKDGPOJN_00753 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KKDGPOJN_00754 2.2e-122 yflK S protein conserved in bacteria
KKDGPOJN_00755 1.5e-14 yflJ S Protein of unknown function (DUF2639)
KKDGPOJN_00756 7e-19 yflI
KKDGPOJN_00757 3.1e-50 yflH S Protein of unknown function (DUF3243)
KKDGPOJN_00758 1.4e-136 map 3.4.11.18 E Methionine aminopeptidase
KKDGPOJN_00759 3.3e-245 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KKDGPOJN_00760 6.3e-73 yfmQ S Uncharacterised protein from bacillus cereus group
KKDGPOJN_00761 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KKDGPOJN_00762 2.3e-63 yhdN S Domain of unknown function (DUF1992)
KKDGPOJN_00763 9.8e-79 cotP O Belongs to the small heat shock protein (HSP20) family
KKDGPOJN_00764 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
KKDGPOJN_00765 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
KKDGPOJN_00766 5.6e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KKDGPOJN_00767 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KKDGPOJN_00768 2.9e-128 treR K transcriptional
KKDGPOJN_00769 1.2e-123 yfkO C nitroreductase
KKDGPOJN_00770 1.2e-124 yibF S YibE/F-like protein
KKDGPOJN_00771 1.1e-198 yibE S YibE/F-like protein
KKDGPOJN_00772 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
KKDGPOJN_00773 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
KKDGPOJN_00774 9.8e-186 K helix_turn _helix lactose operon repressor
KKDGPOJN_00775 5.3e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KKDGPOJN_00776 1.7e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KKDGPOJN_00777 9.6e-193 ydiM EGP Major facilitator Superfamily
KKDGPOJN_00778 7.1e-30 yfkK S Belongs to the UPF0435 family
KKDGPOJN_00779 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KKDGPOJN_00780 1.1e-50 yfkI S gas vesicle protein
KKDGPOJN_00781 1.2e-144 yihY S Belongs to the UPF0761 family
KKDGPOJN_00783 6.5e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
KKDGPOJN_00784 1.3e-185 cax P COG0387 Ca2 H antiporter
KKDGPOJN_00785 4.6e-143 yfkD S YfkD-like protein
KKDGPOJN_00786 1e-145 yfkC M Mechanosensitive ion channel
KKDGPOJN_00787 3e-220 yfkA S YfkB-like domain
KKDGPOJN_00788 4.9e-27 yfjT
KKDGPOJN_00789 9e-155 pdaA G deacetylase
KKDGPOJN_00790 5.2e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KKDGPOJN_00791 6.7e-31
KKDGPOJN_00792 3.8e-184 corA P Mediates influx of magnesium ions
KKDGPOJN_00793 6.3e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KKDGPOJN_00794 1.3e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KKDGPOJN_00796 2.5e-60 M1-386
KKDGPOJN_00797 2.7e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KKDGPOJN_00798 2.1e-90 yfjM S Psort location Cytoplasmic, score
KKDGPOJN_00799 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KKDGPOJN_00800 1.6e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KKDGPOJN_00801 3.2e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KKDGPOJN_00802 3.3e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KKDGPOJN_00803 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KKDGPOJN_00804 4.2e-15 sspH S Belongs to the SspH family
KKDGPOJN_00805 8.4e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KKDGPOJN_00806 1.5e-138 glvR F Helix-turn-helix domain, rpiR family
KKDGPOJN_00807 5.4e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KKDGPOJN_00808 0.0 yfiB3 V ABC transporter
KKDGPOJN_00809 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KKDGPOJN_00810 2.4e-63 mhqP S DoxX
KKDGPOJN_00811 5e-159 yfiE 1.13.11.2 S glyoxalase
KKDGPOJN_00812 8.5e-168 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KKDGPOJN_00813 8.6e-96 padR K transcriptional
KKDGPOJN_00814 1.9e-112 1.6.5.2 S NADPH-dependent FMN reductase
KKDGPOJN_00815 3.4e-181 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KKDGPOJN_00816 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
KKDGPOJN_00817 1.5e-45 yrdF K ribonuclease inhibitor
KKDGPOJN_00818 3.7e-99 yfiT S Belongs to the metal hydrolase YfiT family
KKDGPOJN_00819 6.2e-288 yfiU EGP Major facilitator Superfamily
KKDGPOJN_00820 1.8e-81 yfiV K transcriptional
KKDGPOJN_00821 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KKDGPOJN_00822 4.5e-163 yfhB 5.3.3.17 S PhzF family
KKDGPOJN_00823 3.3e-106 yfhC C nitroreductase
KKDGPOJN_00824 2.1e-25 yfhD S YfhD-like protein
KKDGPOJN_00826 6.8e-167 yfhF S nucleoside-diphosphate sugar epimerase
KKDGPOJN_00827 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
KKDGPOJN_00828 8.8e-53 yfhH S Protein of unknown function (DUF1811)
KKDGPOJN_00829 1.5e-206 yfhI EGP Major facilitator Superfamily
KKDGPOJN_00831 9e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
KKDGPOJN_00832 2.2e-44 yfhJ S WVELL protein
KKDGPOJN_00833 4.5e-94 batE T Bacterial SH3 domain homologues
KKDGPOJN_00834 5.7e-34 yfhL S SdpI/YhfL protein family
KKDGPOJN_00835 1.2e-168 yfhM S Alpha/beta hydrolase family
KKDGPOJN_00836 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KKDGPOJN_00837 0.0 yfhO S Bacterial membrane protein YfhO
KKDGPOJN_00838 1.4e-184 yfhP S membrane-bound metal-dependent
KKDGPOJN_00839 1e-209 mutY L A G-specific
KKDGPOJN_00840 1.8e-36 yfhS
KKDGPOJN_00841 9.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKDGPOJN_00843 1.5e-37 ygaB S YgaB-like protein
KKDGPOJN_00844 2.2e-104 ygaC J Belongs to the UPF0374 family
KKDGPOJN_00845 7.2e-306 ygaD V ABC transporter
KKDGPOJN_00846 3.2e-179 ygaE S Membrane
KKDGPOJN_00847 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KKDGPOJN_00848 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
KKDGPOJN_00849 1.8e-80 perR P Belongs to the Fur family
KKDGPOJN_00850 1.5e-56 ygzB S UPF0295 protein
KKDGPOJN_00851 8.2e-165 ygxA S Nucleotidyltransferase-like
KKDGPOJN_00852 3.4e-39 S COG NOG14552 non supervised orthologous group
KKDGPOJN_00857 7.8e-08
KKDGPOJN_00865 1.6e-08
KKDGPOJN_00869 1.8e-284 C Na+/H+ antiporter family
KKDGPOJN_00870 1.1e-132 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
KKDGPOJN_00871 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KKDGPOJN_00872 9.1e-264 ygaK C Berberine and berberine like
KKDGPOJN_00874 9.8e-231 oppA5 E PFAM extracellular solute-binding protein family 5
KKDGPOJN_00875 5.4e-138 appB P Binding-protein-dependent transport system inner membrane component
KKDGPOJN_00876 3.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKDGPOJN_00877 9.8e-135 oppD3 P Belongs to the ABC transporter superfamily
KKDGPOJN_00878 7.4e-135 oppF3 E Belongs to the ABC transporter superfamily
KKDGPOJN_00879 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KKDGPOJN_00880 2.4e-183 S Amidohydrolase
KKDGPOJN_00881 4.2e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KKDGPOJN_00882 1.1e-178 ssuA M Sulfonate ABC transporter
KKDGPOJN_00883 9.8e-144 ssuC P ABC transporter (permease)
KKDGPOJN_00884 4.2e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KKDGPOJN_00885 1.2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KKDGPOJN_00886 8.6e-81 ygaO
KKDGPOJN_00887 4.8e-23 K Transcriptional regulator
KKDGPOJN_00889 5.1e-113 yhzB S B3/4 domain
KKDGPOJN_00890 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KKDGPOJN_00891 5.5e-175 yhbB S Putative amidase domain
KKDGPOJN_00892 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KKDGPOJN_00893 2.5e-107 yhbD K Protein of unknown function (DUF4004)
KKDGPOJN_00894 8.6e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KKDGPOJN_00895 3.8e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
KKDGPOJN_00897 0.0 prkA T Ser protein kinase
KKDGPOJN_00898 3e-215 yhbH S Belongs to the UPF0229 family
KKDGPOJN_00899 4.6e-74 yhbI K DNA-binding transcription factor activity
KKDGPOJN_00900 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
KKDGPOJN_00901 8.4e-285 yhcA EGP Major facilitator Superfamily
KKDGPOJN_00902 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
KKDGPOJN_00903 7.2e-54 yhcC
KKDGPOJN_00904 3.3e-53
KKDGPOJN_00905 9.5e-62 yhcF K Transcriptional regulator
KKDGPOJN_00906 4.6e-126 yhcG V ABC transporter, ATP-binding protein
KKDGPOJN_00907 2.6e-166 yhcH V ABC transporter, ATP-binding protein
KKDGPOJN_00908 1.1e-162 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KKDGPOJN_00909 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
KKDGPOJN_00910 1.9e-147 metQ M Belongs to the nlpA lipoprotein family
KKDGPOJN_00911 1.3e-185 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
KKDGPOJN_00912 1.9e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KKDGPOJN_00913 1e-51 yhcM
KKDGPOJN_00914 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KKDGPOJN_00915 3.3e-161 yhcP
KKDGPOJN_00916 7.6e-115 yhcQ M Spore coat protein
KKDGPOJN_00917 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
KKDGPOJN_00918 2e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KKDGPOJN_00919 3.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KKDGPOJN_00920 1.3e-69 yhcU S Family of unknown function (DUF5365)
KKDGPOJN_00921 2.6e-68 yhcV S COG0517 FOG CBS domain
KKDGPOJN_00922 4.9e-125 yhcW 5.4.2.6 S hydrolase
KKDGPOJN_00923 1.1e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KKDGPOJN_00924 6.4e-262 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KKDGPOJN_00925 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KKDGPOJN_00926 1.9e-147 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KKDGPOJN_00927 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KKDGPOJN_00928 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KKDGPOJN_00929 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KKDGPOJN_00930 3.2e-206 yhcY 2.7.13.3 T Histidine kinase
KKDGPOJN_00931 1.4e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KKDGPOJN_00932 9.7e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
KKDGPOJN_00933 2.5e-39 yhdB S YhdB-like protein
KKDGPOJN_00934 9e-53 yhdC S Protein of unknown function (DUF3889)
KKDGPOJN_00935 4.7e-218 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KKDGPOJN_00936 5.6e-74 nsrR K Transcriptional regulator
KKDGPOJN_00937 1.3e-255 ygxB M Conserved TM helix
KKDGPOJN_00938 8.7e-270 ycgB S Stage V sporulation protein R
KKDGPOJN_00939 4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KKDGPOJN_00940 6.3e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KKDGPOJN_00941 9e-164 citR K Transcriptional regulator
KKDGPOJN_00942 4.1e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
KKDGPOJN_00943 6.6e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKDGPOJN_00944 2e-250 yhdG E amino acid
KKDGPOJN_00945 6.4e-198 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KKDGPOJN_00946 8.1e-45 yhdK S Sigma-M inhibitor protein
KKDGPOJN_00947 6.6e-201 yhdL S Sigma factor regulator N-terminal
KKDGPOJN_00948 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
KKDGPOJN_00949 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KKDGPOJN_00950 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KKDGPOJN_00951 4.3e-71 cueR K transcriptional
KKDGPOJN_00952 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
KKDGPOJN_00953 1.2e-235 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KKDGPOJN_00954 2.9e-257 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
KKDGPOJN_00955 6.1e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KKDGPOJN_00956 2.4e-60 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KKDGPOJN_00957 2.2e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KKDGPOJN_00959 3e-204 yhdY M Mechanosensitive ion channel
KKDGPOJN_00960 1e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KKDGPOJN_00961 3e-156 yheN G deacetylase
KKDGPOJN_00962 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KKDGPOJN_00963 4.6e-88 pksA K Transcriptional regulator
KKDGPOJN_00964 1.8e-93 ymcC S Membrane
KKDGPOJN_00965 1.8e-84 T universal stress protein
KKDGPOJN_00967 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KKDGPOJN_00968 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KKDGPOJN_00969 6.2e-111 yheG GM NAD(P)H-binding
KKDGPOJN_00971 2.9e-28 sspB S spore protein
KKDGPOJN_00972 1.7e-36 yheE S Family of unknown function (DUF5342)
KKDGPOJN_00973 3e-259 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KKDGPOJN_00974 1.8e-214 yheC HJ YheC/D like ATP-grasp
KKDGPOJN_00975 4.2e-206 yheB S Belongs to the UPF0754 family
KKDGPOJN_00976 4.4e-53 yheA S Belongs to the UPF0342 family
KKDGPOJN_00977 1.7e-202 yhaZ L DNA alkylation repair enzyme
KKDGPOJN_00978 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
KKDGPOJN_00979 9.3e-294 hemZ H coproporphyrinogen III oxidase
KKDGPOJN_00980 3.7e-251 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
KKDGPOJN_00981 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
KKDGPOJN_00982 1.7e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
KKDGPOJN_00984 2e-135 yhaR 5.3.3.18 I enoyl-CoA hydratase
KKDGPOJN_00985 7.3e-15 S YhzD-like protein
KKDGPOJN_00986 6.8e-167 yhaQ S ABC transporter, ATP-binding protein
KKDGPOJN_00987 4e-205 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KKDGPOJN_00988 1e-234 yhaO L DNA repair exonuclease
KKDGPOJN_00989 0.0 yhaN L AAA domain
KKDGPOJN_00990 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
KKDGPOJN_00991 1.6e-32 yhaL S Sporulation protein YhaL
KKDGPOJN_00992 1.7e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KKDGPOJN_00993 7e-95 yhaK S Putative zincin peptidase
KKDGPOJN_00994 9.9e-55 yhaI S Protein of unknown function (DUF1878)
KKDGPOJN_00995 3.3e-112 hpr K Negative regulator of protease production and sporulation
KKDGPOJN_00996 2.4e-38 yhaH S YtxH-like protein
KKDGPOJN_00997 5.2e-18
KKDGPOJN_00998 2.4e-76 trpP S Tryptophan transporter TrpP
KKDGPOJN_00999 2.7e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KKDGPOJN_01000 6.9e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KKDGPOJN_01001 1.1e-135 ecsA V transporter (ATP-binding protein)
KKDGPOJN_01002 4.7e-219 ecsB U ABC transporter
KKDGPOJN_01003 3.6e-123 ecsC S EcsC protein family
KKDGPOJN_01004 6.1e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KKDGPOJN_01005 5.3e-243 yhfA C membrane
KKDGPOJN_01006 6.4e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KKDGPOJN_01007 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KKDGPOJN_01008 3.3e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KKDGPOJN_01009 6.2e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KKDGPOJN_01010 2e-274 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KKDGPOJN_01011 3.2e-101 yhgD K Transcriptional regulator
KKDGPOJN_01012 2.1e-276 yhgE S YhgE Pip N-terminal domain protein
KKDGPOJN_01013 3.7e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KKDGPOJN_01015 2.5e-197 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
KKDGPOJN_01016 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KKDGPOJN_01017 5.8e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KKDGPOJN_01018 1.3e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
KKDGPOJN_01019 1.7e-111 yhfK GM NmrA-like family
KKDGPOJN_01020 2.4e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KKDGPOJN_01021 1.9e-65 yhfM
KKDGPOJN_01022 3.6e-235 yhfN 3.4.24.84 O Peptidase M48
KKDGPOJN_01023 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
KKDGPOJN_01024 4.6e-152 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KKDGPOJN_01025 4.4e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KKDGPOJN_01026 2.4e-198 vraB 2.3.1.9 I Belongs to the thiolase family
KKDGPOJN_01027 6.6e-273 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KKDGPOJN_01028 3.5e-89 bioY S BioY family
KKDGPOJN_01029 1.5e-199 hemAT NT chemotaxis protein
KKDGPOJN_01030 4.8e-298 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KKDGPOJN_01031 8.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKDGPOJN_01032 1.8e-31 yhzC S IDEAL
KKDGPOJN_01033 1.9e-109 comK K Competence transcription factor
KKDGPOJN_01034 3.9e-68 frataxin S Domain of unknown function (DU1801)
KKDGPOJN_01035 2.4e-65 frataxin S Domain of unknown function (DU1801)
KKDGPOJN_01036 1.7e-90 mepB S MepB protein
KKDGPOJN_01037 5.2e-15 yrpD S Domain of unknown function, YrpD
KKDGPOJN_01038 5.1e-125 yrpD S Domain of unknown function, YrpD
KKDGPOJN_01039 1.6e-42 yhjA S Excalibur calcium-binding domain
KKDGPOJN_01040 3.3e-47 S Belongs to the UPF0145 family
KKDGPOJN_01041 9.5e-267 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKDGPOJN_01042 1.4e-27 yhjC S Protein of unknown function (DUF3311)
KKDGPOJN_01043 2.9e-60 yhjD
KKDGPOJN_01044 7.7e-109 yhjE S SNARE associated Golgi protein
KKDGPOJN_01045 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
KKDGPOJN_01046 3.9e-276 yhjG CH FAD binding domain
KKDGPOJN_01047 5.8e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
KKDGPOJN_01048 1.3e-186 abrB S membrane
KKDGPOJN_01049 2.1e-203 blt EGP Major facilitator Superfamily
KKDGPOJN_01050 1.1e-107 K QacR-like protein, C-terminal region
KKDGPOJN_01051 9.7e-94 yhjR S Rubrerythrin
KKDGPOJN_01052 3.3e-124 ydfS S Protein of unknown function (DUF421)
KKDGPOJN_01053 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KKDGPOJN_01054 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KKDGPOJN_01055 2.2e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KKDGPOJN_01056 0.0 sbcC L COG0419 ATPase involved in DNA repair
KKDGPOJN_01057 5.5e-49 yisB V COG1403 Restriction endonuclease
KKDGPOJN_01058 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
KKDGPOJN_01059 1.2e-62 gerPE S Spore germination protein GerPE
KKDGPOJN_01060 1.2e-22 gerPD S Spore germination protein
KKDGPOJN_01061 9.1e-62 gerPC S Spore germination protein
KKDGPOJN_01062 6.2e-35 gerPB S cell differentiation
KKDGPOJN_01063 8.4e-34 gerPA S Spore germination protein
KKDGPOJN_01064 5e-07 yisI S Spo0E like sporulation regulatory protein
KKDGPOJN_01065 1.2e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KKDGPOJN_01066 3.2e-59 yisL S UPF0344 protein
KKDGPOJN_01067 6.5e-96 yisN S Protein of unknown function (DUF2777)
KKDGPOJN_01068 0.0 asnO 6.3.5.4 E Asparagine synthase
KKDGPOJN_01069 1.7e-131 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
KKDGPOJN_01070 1.9e-245 yisQ V Mate efflux family protein
KKDGPOJN_01071 6.6e-159 yisR K Transcriptional regulator
KKDGPOJN_01072 7.1e-144 purR K helix_turn _helix lactose operon repressor
KKDGPOJN_01073 3.6e-156 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
KKDGPOJN_01074 6.8e-84 yisT S DinB family
KKDGPOJN_01075 9.8e-72 mcbG S Pentapeptide repeats (9 copies)
KKDGPOJN_01076 2.4e-80 yjcF S Acetyltransferase (GNAT) domain
KKDGPOJN_01077 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KKDGPOJN_01078 1.8e-52 yajQ S Belongs to the UPF0234 family
KKDGPOJN_01079 1.8e-161 cvfB S protein conserved in bacteria
KKDGPOJN_01080 1.4e-173 yufN S ABC transporter substrate-binding protein PnrA-like
KKDGPOJN_01081 4.7e-230 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KKDGPOJN_01082 6.9e-242 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KKDGPOJN_01084 5.5e-158 yitS S protein conserved in bacteria
KKDGPOJN_01085 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
KKDGPOJN_01086 2.9e-81 ipi S Intracellular proteinase inhibitor
KKDGPOJN_01087 4.4e-26 S Protein of unknown function (DUF3813)
KKDGPOJN_01088 3.5e-07
KKDGPOJN_01089 5.1e-153 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KKDGPOJN_01090 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KKDGPOJN_01091 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
KKDGPOJN_01092 2.4e-80 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KKDGPOJN_01093 3.5e-272 yitY C D-arabinono-1,4-lactone oxidase
KKDGPOJN_01094 1.2e-89 norB G Major Facilitator Superfamily
KKDGPOJN_01095 6.8e-195 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KKDGPOJN_01096 4.6e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KKDGPOJN_01097 3.5e-135 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
KKDGPOJN_01098 1.7e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KKDGPOJN_01099 3.8e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KKDGPOJN_01100 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KKDGPOJN_01101 3.5e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KKDGPOJN_01102 1.2e-27 yjzC S YjzC-like protein
KKDGPOJN_01103 1.5e-23 yjzD S Protein of unknown function (DUF2929)
KKDGPOJN_01104 1.3e-139 yjaU I carboxylic ester hydrolase activity
KKDGPOJN_01105 1.4e-104 yjaV
KKDGPOJN_01106 1.9e-166 med S Transcriptional activator protein med
KKDGPOJN_01107 1.1e-26 comZ S ComZ
KKDGPOJN_01108 5.9e-32 yjzB
KKDGPOJN_01109 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KKDGPOJN_01110 2.9e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KKDGPOJN_01111 1.8e-147 yjaZ O Zn-dependent protease
KKDGPOJN_01112 3.7e-182 appD P Belongs to the ABC transporter superfamily
KKDGPOJN_01113 8.5e-187 appF E Belongs to the ABC transporter superfamily
KKDGPOJN_01114 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
KKDGPOJN_01115 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKDGPOJN_01116 1.1e-161 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKDGPOJN_01117 5.5e-146 yjbA S Belongs to the UPF0736 family
KKDGPOJN_01118 3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KKDGPOJN_01119 0.0 oppA E ABC transporter substrate-binding protein
KKDGPOJN_01120 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKDGPOJN_01121 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKDGPOJN_01122 2.7e-202 oppD P Belongs to the ABC transporter superfamily
KKDGPOJN_01123 1.1e-169 oppF E Belongs to the ABC transporter superfamily
KKDGPOJN_01124 1.3e-229 S Putative glycosyl hydrolase domain
KKDGPOJN_01125 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KKDGPOJN_01126 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KKDGPOJN_01127 5.6e-110 yjbE P Integral membrane protein TerC family
KKDGPOJN_01128 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KKDGPOJN_01129 9.3e-217 yjbF S Competence protein
KKDGPOJN_01130 0.0 pepF E oligoendopeptidase F
KKDGPOJN_01131 5.8e-19
KKDGPOJN_01132 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KKDGPOJN_01133 4.8e-72 yjbI S Bacterial-like globin
KKDGPOJN_01134 2.1e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KKDGPOJN_01135 5.1e-99 yjbK S protein conserved in bacteria
KKDGPOJN_01136 1.6e-61 yjbL S Belongs to the UPF0738 family
KKDGPOJN_01137 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
KKDGPOJN_01138 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KKDGPOJN_01139 1e-162 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KKDGPOJN_01140 9.7e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KKDGPOJN_01141 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KKDGPOJN_01142 5.2e-138 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KKDGPOJN_01143 7.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
KKDGPOJN_01144 5.4e-214 thiO 1.4.3.19 E Glycine oxidase
KKDGPOJN_01145 1.4e-30 thiS H Thiamine biosynthesis
KKDGPOJN_01146 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KKDGPOJN_01147 2.3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KKDGPOJN_01148 4.1e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KKDGPOJN_01149 1.2e-138 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KKDGPOJN_01150 1.1e-83 yjbX S Spore coat protein
KKDGPOJN_01151 6.7e-83 cotZ S Spore coat protein
KKDGPOJN_01152 4.6e-93 cotY S Spore coat protein Z
KKDGPOJN_01153 5.1e-71 cotX S Spore Coat Protein X and V domain
KKDGPOJN_01154 1e-21 cotW
KKDGPOJN_01155 1.4e-39 cotV S Spore Coat Protein X and V domain
KKDGPOJN_01156 7.3e-56 yjcA S Protein of unknown function (DUF1360)
KKDGPOJN_01160 3.8e-38 spoVIF S Stage VI sporulation protein F
KKDGPOJN_01161 0.0 yjcD 3.6.4.12 L DNA helicase
KKDGPOJN_01162 6.7e-35
KKDGPOJN_01163 3.1e-141 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
KKDGPOJN_01164 7.5e-124 S ABC-2 type transporter
KKDGPOJN_01165 7.6e-132 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
KKDGPOJN_01166 9.4e-36 K SpoVT / AbrB like domain
KKDGPOJN_01167 1.2e-73 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KKDGPOJN_01168 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KKDGPOJN_01169 2.7e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
KKDGPOJN_01170 6.2e-210 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KKDGPOJN_01171 1.5e-214 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KKDGPOJN_01177 4e-28
KKDGPOJN_01179 1.7e-11
KKDGPOJN_01184 2.3e-08
KKDGPOJN_01185 3.7e-10 K Transcriptional regulator
KKDGPOJN_01188 2.5e-46
KKDGPOJN_01191 5.5e-10 yqaS L DNA packaging
KKDGPOJN_01192 2.4e-10 yqaS L DNA packaging
KKDGPOJN_01193 1.2e-147 bla 3.5.2.6 V beta-lactamase
KKDGPOJN_01194 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
KKDGPOJN_01195 2.7e-250 yfjF EGP Belongs to the major facilitator superfamily
KKDGPOJN_01196 1.4e-81 napB K helix_turn_helix multiple antibiotic resistance protein
KKDGPOJN_01197 3.6e-218 ganA 3.2.1.89 G arabinogalactan
KKDGPOJN_01198 7.6e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KKDGPOJN_01199 1.6e-185 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KKDGPOJN_01200 1.3e-215 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KKDGPOJN_01201 1.2e-310 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKDGPOJN_01202 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
KKDGPOJN_01203 3.4e-282 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
KKDGPOJN_01204 2.2e-137 lacR K COG1349 Transcriptional regulators of sugar metabolism
KKDGPOJN_01205 4.9e-125 5.4.2.6 S Haloacid dehalogenase-like hydrolase
KKDGPOJN_01206 2.6e-34
KKDGPOJN_01207 3.8e-51 K helix_turn_helix multiple antibiotic resistance protein
KKDGPOJN_01208 8.1e-106 yhiD S MgtC SapB transporter
KKDGPOJN_01210 1.1e-20 yjfB S Putative motility protein
KKDGPOJN_01211 1.2e-65 T PhoQ Sensor
KKDGPOJN_01212 5.9e-100 yjgB S Domain of unknown function (DUF4309)
KKDGPOJN_01213 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KKDGPOJN_01214 4.3e-92 yjgD S Protein of unknown function (DUF1641)
KKDGPOJN_01215 3.1e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
KKDGPOJN_01216 2.6e-222 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KKDGPOJN_01217 6.8e-29
KKDGPOJN_01218 2.1e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KKDGPOJN_01219 1.8e-120 ybbM S transport system, permease component
KKDGPOJN_01220 4.6e-129 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
KKDGPOJN_01221 1.5e-175 yjlA EG Putative multidrug resistance efflux transporter
KKDGPOJN_01222 1.5e-91 yjlB S Cupin domain
KKDGPOJN_01223 7e-66 yjlC S Protein of unknown function (DUF1641)
KKDGPOJN_01224 1.3e-218 yjlD 1.6.99.3 C NADH dehydrogenase
KKDGPOJN_01225 3.3e-277 uxaC 5.3.1.12 G glucuronate isomerase
KKDGPOJN_01226 3.9e-254 yjmB G symporter YjmB
KKDGPOJN_01227 1.7e-182 exuR K transcriptional
KKDGPOJN_01228 3.7e-276 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KKDGPOJN_01229 2.2e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KKDGPOJN_01230 3.9e-131 MA20_18170 S membrane transporter protein
KKDGPOJN_01231 3.1e-78 yjoA S DinB family
KKDGPOJN_01232 4.9e-215 S response regulator aspartate phosphatase
KKDGPOJN_01234 8.5e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KKDGPOJN_01235 2.3e-60 yjqA S Bacterial PH domain
KKDGPOJN_01236 2.5e-109 yjqB S phage-related replication protein
KKDGPOJN_01237 1.1e-147 ydbD P Catalase
KKDGPOJN_01238 2.5e-109 xkdA E IrrE N-terminal-like domain
KKDGPOJN_01239 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
KKDGPOJN_01241 7.2e-152 xkdC L Bacterial dnaA protein
KKDGPOJN_01244 2e-10 yqaO S Phage-like element PBSX protein XtrA
KKDGPOJN_01245 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KKDGPOJN_01246 6.1e-111 xtmA L phage terminase small subunit
KKDGPOJN_01247 6.1e-209 xtmB S phage terminase, large subunit
KKDGPOJN_01248 5.1e-241 yqbA S portal protein
KKDGPOJN_01249 6.3e-90 xkdF 2.1.1.72 L Putative phage serine protease XkdF
KKDGPOJN_01250 1e-157 xkdG S Phage capsid family
KKDGPOJN_01251 5.7e-46 yqbG S Protein of unknown function (DUF3199)
KKDGPOJN_01252 4.6e-42 yqbH S Domain of unknown function (DUF3599)
KKDGPOJN_01253 3.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
KKDGPOJN_01254 4.9e-57 xkdJ
KKDGPOJN_01255 3.1e-14
KKDGPOJN_01256 1e-225 xkdK S Phage tail sheath C-terminal domain
KKDGPOJN_01257 2e-74 xkdM S Phage tail tube protein
KKDGPOJN_01258 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
KKDGPOJN_01259 3.4e-19
KKDGPOJN_01260 3.3e-186 xkdO L Transglycosylase SLT domain
KKDGPOJN_01261 5.1e-111 xkdP S Lysin motif
KKDGPOJN_01262 7.9e-161 xkdQ 3.2.1.96 G NLP P60 protein
KKDGPOJN_01263 1.6e-31 xkdR S Protein of unknown function (DUF2577)
KKDGPOJN_01264 7.2e-58 xkdS S Protein of unknown function (DUF2634)
KKDGPOJN_01265 3.3e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KKDGPOJN_01266 5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KKDGPOJN_01267 1.2e-26
KKDGPOJN_01268 9.9e-92
KKDGPOJN_01270 6.5e-30 xkdX
KKDGPOJN_01271 6.2e-137 xepA
KKDGPOJN_01272 5.6e-37 xhlA S Haemolysin XhlA
KKDGPOJN_01273 2.3e-38 xhlB S SPP1 phage holin
KKDGPOJN_01274 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KKDGPOJN_01275 8.7e-23 spoIISB S Stage II sporulation protein SB
KKDGPOJN_01276 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KKDGPOJN_01277 5.8e-175 pit P phosphate transporter
KKDGPOJN_01278 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
KKDGPOJN_01279 3.8e-243 steT E amino acid
KKDGPOJN_01280 1.4e-178 mhqA E COG0346 Lactoylglutathione lyase and related lyases
KKDGPOJN_01281 1.3e-301 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KKDGPOJN_01282 1.2e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KKDGPOJN_01284 2.6e-202 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KKDGPOJN_01285 9e-284 yubD P Major Facilitator Superfamily
KKDGPOJN_01287 6.5e-156 dppA E D-aminopeptidase
KKDGPOJN_01288 1.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKDGPOJN_01289 8.5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKDGPOJN_01290 2e-191 dppD P Belongs to the ABC transporter superfamily
KKDGPOJN_01291 0.0 dppE E ABC transporter substrate-binding protein
KKDGPOJN_01292 1.6e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KKDGPOJN_01293 2.6e-197 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KKDGPOJN_01294 5e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KKDGPOJN_01295 9.6e-183 ykfD E Belongs to the ABC transporter superfamily
KKDGPOJN_01296 1.5e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
KKDGPOJN_01297 1.9e-158 ykgA E Amidinotransferase
KKDGPOJN_01298 1.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KKDGPOJN_01299 1.5e-100 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KKDGPOJN_01300 2.7e-52 ykkC P Multidrug resistance protein
KKDGPOJN_01301 3.4e-49 ykkD P Multidrug resistance protein
KKDGPOJN_01302 8.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KKDGPOJN_01303 1.6e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KKDGPOJN_01304 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KKDGPOJN_01305 1.3e-70 ohrA O Organic hydroperoxide resistance protein
KKDGPOJN_01306 1.5e-86 ohrR K COG1846 Transcriptional regulators
KKDGPOJN_01307 4.2e-71 ohrB O Organic hydroperoxide resistance protein
KKDGPOJN_01308 1.1e-56 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KKDGPOJN_01310 1.9e-214 M Glycosyl transferase family 2
KKDGPOJN_01311 2.4e-113 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
KKDGPOJN_01312 5.5e-217 hcaT 1.5.1.2 EGP Major facilitator Superfamily
KKDGPOJN_01313 3.6e-120 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KKDGPOJN_01314 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KKDGPOJN_01315 3.8e-176 isp O Belongs to the peptidase S8 family
KKDGPOJN_01316 5.2e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KKDGPOJN_01317 2.1e-132 ykoC P Cobalt transport protein
KKDGPOJN_01318 3.4e-305 P ABC transporter, ATP-binding protein
KKDGPOJN_01319 3.4e-98 ykoE S ABC-type cobalt transport system, permease component
KKDGPOJN_01320 1e-245 ydhD M Glycosyl hydrolase
KKDGPOJN_01322 2.2e-238 mgtE P Acts as a magnesium transporter
KKDGPOJN_01323 1.6e-52 tnrA K transcriptional
KKDGPOJN_01324 1.9e-16
KKDGPOJN_01325 3.1e-26 ykoL
KKDGPOJN_01326 1.1e-80 ykoM K transcriptional
KKDGPOJN_01327 2.2e-99 ykoP G polysaccharide deacetylase
KKDGPOJN_01328 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
KKDGPOJN_01329 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KKDGPOJN_01330 3.8e-99 ykoX S membrane-associated protein
KKDGPOJN_01331 2.1e-135 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KKDGPOJN_01332 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKDGPOJN_01333 3.1e-119 rsgI S Anti-sigma factor N-terminus
KKDGPOJN_01334 2.5e-26 sspD S small acid-soluble spore protein
KKDGPOJN_01335 2.7e-126 ykrK S Domain of unknown function (DUF1836)
KKDGPOJN_01336 4.1e-156 htpX O Belongs to the peptidase M48B family
KKDGPOJN_01337 1.3e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
KKDGPOJN_01338 3.8e-114 ydfR S Protein of unknown function (DUF421)
KKDGPOJN_01339 7.9e-24 ykzE
KKDGPOJN_01340 3.6e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KKDGPOJN_01341 0.0 kinE 2.7.13.3 T Histidine kinase
KKDGPOJN_01342 1.5e-86 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KKDGPOJN_01344 6.3e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KKDGPOJN_01345 1e-226 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KKDGPOJN_01346 8.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KKDGPOJN_01347 1.2e-227 mtnE 2.6.1.83 E Aminotransferase
KKDGPOJN_01348 1.8e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KKDGPOJN_01349 1.2e-134 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KKDGPOJN_01350 3.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KKDGPOJN_01351 6.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KKDGPOJN_01352 3.4e-10 S Spo0E like sporulation regulatory protein
KKDGPOJN_01353 2.1e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
KKDGPOJN_01354 5.5e-77 ykvE K transcriptional
KKDGPOJN_01355 4.6e-127 motB N Flagellar motor protein
KKDGPOJN_01356 1.1e-136 motA N flagellar motor
KKDGPOJN_01357 0.0 clpE O Belongs to the ClpA ClpB family
KKDGPOJN_01358 7.8e-183 ykvI S membrane
KKDGPOJN_01359 9e-185
KKDGPOJN_01360 2.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KKDGPOJN_01361 1.3e-78 queD 4.1.2.50, 4.2.3.12 H synthase
KKDGPOJN_01362 2.2e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KKDGPOJN_01363 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KKDGPOJN_01364 5.8e-61 ykvN K Transcriptional regulator
KKDGPOJN_01365 4.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
KKDGPOJN_01366 5.9e-31 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KKDGPOJN_01367 1.7e-44 ykvR S Protein of unknown function (DUF3219)
KKDGPOJN_01368 7.8e-25 ykvS S protein conserved in bacteria
KKDGPOJN_01369 7.9e-28
KKDGPOJN_01370 2.6e-109 ykvT 3.5.1.28 M Cell Wall Hydrolase
KKDGPOJN_01371 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KKDGPOJN_01372 7.7e-88 stoA CO thiol-disulfide
KKDGPOJN_01373 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KKDGPOJN_01374 2.4e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KKDGPOJN_01376 1.7e-176 ykvZ 5.1.1.1 K Transcriptional regulator
KKDGPOJN_01377 5.1e-156 glcT K antiterminator
KKDGPOJN_01378 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KKDGPOJN_01379 2.1e-39 ptsH G phosphocarrier protein HPr
KKDGPOJN_01380 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KKDGPOJN_01381 6.1e-38 splA S Transcriptional regulator
KKDGPOJN_01382 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
KKDGPOJN_01383 1.4e-255 mcpC NT chemotaxis protein
KKDGPOJN_01384 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KKDGPOJN_01385 8e-64
KKDGPOJN_01386 1.5e-114 ykwD J protein with SCP PR1 domains
KKDGPOJN_01387 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
KKDGPOJN_01388 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
KKDGPOJN_01389 3.9e-215 patA 2.6.1.1 E Aminotransferase
KKDGPOJN_01390 2.3e-09
KKDGPOJN_01391 2.6e-166 cheV 2.7.13.3 T Chemotaxis protein CheV
KKDGPOJN_01392 1.4e-83 ykyB S YkyB-like protein
KKDGPOJN_01393 8.7e-240 ykuC EGP Major facilitator Superfamily
KKDGPOJN_01394 1.2e-88 ykuD S protein conserved in bacteria
KKDGPOJN_01395 1.4e-153 ykuE S Metallophosphoesterase
KKDGPOJN_01396 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKDGPOJN_01398 1.7e-232 ykuI T Diguanylate phosphodiesterase
KKDGPOJN_01399 3.9e-37 ykuJ S protein conserved in bacteria
KKDGPOJN_01400 7.6e-94 ykuK S Ribonuclease H-like
KKDGPOJN_01401 2.1e-25 ykzF S Antirepressor AbbA
KKDGPOJN_01402 1e-75 ykuL S CBS domain
KKDGPOJN_01403 4.6e-168 ccpC K Transcriptional regulator
KKDGPOJN_01404 6.1e-90 fld C Flavodoxin
KKDGPOJN_01405 8.2e-173 ykuO
KKDGPOJN_01406 2.1e-79 fld C Flavodoxin
KKDGPOJN_01407 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KKDGPOJN_01408 1.5e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KKDGPOJN_01409 4.8e-38 ykuS S Belongs to the UPF0180 family
KKDGPOJN_01410 1.9e-139 ykuT M Mechanosensitive ion channel
KKDGPOJN_01411 2.3e-78 ykuV CO thiol-disulfide
KKDGPOJN_01412 4.5e-98 rok K Repressor of ComK
KKDGPOJN_01413 2.5e-162 yknT
KKDGPOJN_01414 8.2e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KKDGPOJN_01415 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KKDGPOJN_01416 2.9e-243 moeA 2.10.1.1 H molybdopterin
KKDGPOJN_01417 2.2e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KKDGPOJN_01418 4.6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KKDGPOJN_01419 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KKDGPOJN_01420 2.4e-103 yknW S Yip1 domain
KKDGPOJN_01421 3.4e-171 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KKDGPOJN_01422 6.1e-123 macB V ABC transporter, ATP-binding protein
KKDGPOJN_01423 3.9e-210 yknZ V ABC transporter (permease)
KKDGPOJN_01424 4.6e-132 fruR K Transcriptional regulator
KKDGPOJN_01425 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KKDGPOJN_01426 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KKDGPOJN_01427 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KKDGPOJN_01428 1.3e-36 ykoA
KKDGPOJN_01429 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KKDGPOJN_01430 2.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KKDGPOJN_01431 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KKDGPOJN_01432 5.5e-12 S Uncharacterized protein YkpC
KKDGPOJN_01433 7.7e-183 mreB D Rod-share determining protein MreBH
KKDGPOJN_01434 1.8e-44 abrB K of stationary sporulation gene expression
KKDGPOJN_01435 6.3e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KKDGPOJN_01436 4.5e-149 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
KKDGPOJN_01437 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
KKDGPOJN_01438 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KKDGPOJN_01439 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KKDGPOJN_01440 8.2e-31 ykzG S Belongs to the UPF0356 family
KKDGPOJN_01441 9.7e-146 ykrA S hydrolases of the HAD superfamily
KKDGPOJN_01442 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KKDGPOJN_01444 2.9e-103 recN L Putative cell-wall binding lipoprotein
KKDGPOJN_01445 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KKDGPOJN_01446 0.0 Q Polyketide synthase of type I
KKDGPOJN_01447 0.0 Q polyketide synthase
KKDGPOJN_01448 0.0 Q Polyketide synthase of type I
KKDGPOJN_01449 0.0 Q Polyketide synthase of type I
KKDGPOJN_01450 0.0 Q Polyketide synthase of type I
KKDGPOJN_01451 0.0 Q Polyketide synthase of type I
KKDGPOJN_01452 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
KKDGPOJN_01453 2.7e-210 V Beta-lactamase
KKDGPOJN_01454 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KKDGPOJN_01455 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KKDGPOJN_01456 2.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KKDGPOJN_01457 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KKDGPOJN_01458 4.7e-45 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
KKDGPOJN_01459 9.3e-136 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
KKDGPOJN_01460 1.3e-276 speA 4.1.1.19 E Arginine
KKDGPOJN_01461 1.6e-42 yktA S Belongs to the UPF0223 family
KKDGPOJN_01462 4.9e-119 yktB S Belongs to the UPF0637 family
KKDGPOJN_01463 6.3e-24 ykzI
KKDGPOJN_01464 2.3e-150 suhB 3.1.3.25 G Inositol monophosphatase
KKDGPOJN_01465 1.5e-82 ykzC S Acetyltransferase (GNAT) family
KKDGPOJN_01466 1.9e-294 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
KKDGPOJN_01467 4e-188 ylaA
KKDGPOJN_01468 1.1e-43 ylaB
KKDGPOJN_01469 5.5e-92 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
KKDGPOJN_01470 2.8e-13 sigC S Putative zinc-finger
KKDGPOJN_01471 4.9e-39 ylaE
KKDGPOJN_01472 6.7e-24 S Family of unknown function (DUF5325)
KKDGPOJN_01473 0.0 typA T GTP-binding protein TypA
KKDGPOJN_01474 1.3e-48 ylaH S YlaH-like protein
KKDGPOJN_01475 1e-33 ylaI S protein conserved in bacteria
KKDGPOJN_01476 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KKDGPOJN_01477 3.2e-245 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KKDGPOJN_01478 2.2e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KKDGPOJN_01479 2.1e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
KKDGPOJN_01480 8.7e-44 ylaN S Belongs to the UPF0358 family
KKDGPOJN_01481 9.4e-212 ftsW D Belongs to the SEDS family
KKDGPOJN_01482 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KKDGPOJN_01483 3.3e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KKDGPOJN_01484 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KKDGPOJN_01485 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KKDGPOJN_01486 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KKDGPOJN_01487 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KKDGPOJN_01488 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KKDGPOJN_01489 2.8e-165 ctaG S cytochrome c oxidase
KKDGPOJN_01490 8.5e-60 ylbA S YugN-like family
KKDGPOJN_01491 6.3e-73 ylbB T COG0517 FOG CBS domain
KKDGPOJN_01492 1.7e-198 ylbC S protein with SCP PR1 domains
KKDGPOJN_01493 6.5e-56 ylbD S Putative coat protein
KKDGPOJN_01494 8.8e-37 ylbE S YlbE-like protein
KKDGPOJN_01495 1.2e-71 ylbF S Belongs to the UPF0342 family
KKDGPOJN_01496 7.2e-43 ylbG S UPF0298 protein
KKDGPOJN_01498 8.5e-90 rsmD 2.1.1.171 L Methyltransferase
KKDGPOJN_01499 7.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KKDGPOJN_01500 1.7e-216 ylbJ S Sporulation integral membrane protein YlbJ
KKDGPOJN_01501 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
KKDGPOJN_01502 5.5e-189 ylbL T Belongs to the peptidase S16 family
KKDGPOJN_01503 5.1e-229 ylbM S Belongs to the UPF0348 family
KKDGPOJN_01504 3.3e-89 yceD S metal-binding, possibly nucleic acid-binding protein
KKDGPOJN_01505 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KKDGPOJN_01506 7.6e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KKDGPOJN_01507 3.1e-89 ylbP K n-acetyltransferase
KKDGPOJN_01508 6.7e-162 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KKDGPOJN_01509 5.7e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KKDGPOJN_01510 1.2e-77 mraZ K Belongs to the MraZ family
KKDGPOJN_01511 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KKDGPOJN_01512 1.1e-51 ftsL D Essential cell division protein
KKDGPOJN_01513 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KKDGPOJN_01514 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KKDGPOJN_01515 7.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KKDGPOJN_01516 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KKDGPOJN_01517 5.9e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KKDGPOJN_01518 2.2e-185 spoVE D Belongs to the SEDS family
KKDGPOJN_01519 3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KKDGPOJN_01520 3.7e-168 murB 1.3.1.98 M cell wall formation
KKDGPOJN_01521 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KKDGPOJN_01522 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KKDGPOJN_01523 5.8e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KKDGPOJN_01524 0.0 bpr O COG1404 Subtilisin-like serine proteases
KKDGPOJN_01525 8.9e-162 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KKDGPOJN_01526 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKDGPOJN_01527 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKDGPOJN_01528 1.7e-145 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KKDGPOJN_01529 1.6e-254 argE 3.5.1.16 E Acetylornithine deacetylase
KKDGPOJN_01530 2.2e-38 ylmC S sporulation protein
KKDGPOJN_01531 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KKDGPOJN_01532 3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KKDGPOJN_01533 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KKDGPOJN_01534 5.2e-41 yggT S membrane
KKDGPOJN_01535 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KKDGPOJN_01536 8.9e-68 divIVA D Cell division initiation protein
KKDGPOJN_01537 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KKDGPOJN_01538 3.8e-63 dksA T COG1734 DnaK suppressor protein
KKDGPOJN_01539 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KKDGPOJN_01540 6.7e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KKDGPOJN_01541 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KKDGPOJN_01542 5.2e-232 pyrP F Xanthine uracil
KKDGPOJN_01543 1.8e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KKDGPOJN_01544 5e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KKDGPOJN_01545 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KKDGPOJN_01546 0.0 carB 6.3.5.5 F Belongs to the CarB family
KKDGPOJN_01547 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KKDGPOJN_01548 3e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KKDGPOJN_01549 3.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KKDGPOJN_01550 7.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KKDGPOJN_01552 8.5e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KKDGPOJN_01553 1.8e-179 cysP P phosphate transporter
KKDGPOJN_01554 3.8e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KKDGPOJN_01555 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
KKDGPOJN_01556 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KKDGPOJN_01557 2.9e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KKDGPOJN_01558 7.6e-80 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KKDGPOJN_01559 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KKDGPOJN_01560 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KKDGPOJN_01561 1e-154 yloC S stress-induced protein
KKDGPOJN_01562 1.5e-40 ylzA S Belongs to the UPF0296 family
KKDGPOJN_01563 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KKDGPOJN_01564 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KKDGPOJN_01565 5.7e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KKDGPOJN_01566 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KKDGPOJN_01567 2.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KKDGPOJN_01568 1.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KKDGPOJN_01569 2.3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KKDGPOJN_01570 2.6e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KKDGPOJN_01571 1.7e-139 stp 3.1.3.16 T phosphatase
KKDGPOJN_01572 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KKDGPOJN_01573 8.2e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KKDGPOJN_01574 2.3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KKDGPOJN_01575 5.8e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
KKDGPOJN_01576 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KKDGPOJN_01577 5.5e-59 asp S protein conserved in bacteria
KKDGPOJN_01578 3.8e-304 yloV S kinase related to dihydroxyacetone kinase
KKDGPOJN_01579 2.8e-117 sdaAB 4.3.1.17 E L-serine dehydratase
KKDGPOJN_01580 8.7e-154 sdaAA 4.3.1.17 E L-serine dehydratase
KKDGPOJN_01581 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KKDGPOJN_01582 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KKDGPOJN_01583 6.2e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KKDGPOJN_01584 7e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KKDGPOJN_01585 4.6e-129 IQ reductase
KKDGPOJN_01586 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KKDGPOJN_01587 4.4e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KKDGPOJN_01588 0.0 smc D Required for chromosome condensation and partitioning
KKDGPOJN_01589 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KKDGPOJN_01590 3.2e-141 S Phosphotransferase enzyme family
KKDGPOJN_01591 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KKDGPOJN_01592 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KKDGPOJN_01593 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KKDGPOJN_01594 1.7e-35 ylqC S Belongs to the UPF0109 family
KKDGPOJN_01595 1.3e-61 ylqD S YlqD protein
KKDGPOJN_01596 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KKDGPOJN_01597 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KKDGPOJN_01598 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KKDGPOJN_01599 6.4e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KKDGPOJN_01600 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KKDGPOJN_01601 7e-306 ylqG
KKDGPOJN_01602 6.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KKDGPOJN_01603 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KKDGPOJN_01604 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KKDGPOJN_01605 1.6e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KKDGPOJN_01606 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KKDGPOJN_01607 2.8e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KKDGPOJN_01608 7.2e-172 xerC L tyrosine recombinase XerC
KKDGPOJN_01609 2e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KKDGPOJN_01610 6.3e-228 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KKDGPOJN_01611 1.7e-134 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KKDGPOJN_01612 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KKDGPOJN_01613 2.4e-75 flgC N Belongs to the flagella basal body rod proteins family
KKDGPOJN_01614 2.5e-31 fliE N Flagellar hook-basal body
KKDGPOJN_01615 2.6e-262 fliF N The M ring may be actively involved in energy transduction
KKDGPOJN_01616 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KKDGPOJN_01617 4.3e-90 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KKDGPOJN_01618 5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KKDGPOJN_01619 4.5e-71 fliJ N Flagellar biosynthesis chaperone
KKDGPOJN_01620 4.8e-47 ylxF S MgtE intracellular N domain
KKDGPOJN_01621 7.2e-205 fliK N Flagellar hook-length control protein
KKDGPOJN_01622 5.3e-72 flgD N Flagellar basal body rod modification protein
KKDGPOJN_01623 4e-139 flgG N Flagellar basal body rod
KKDGPOJN_01624 2.3e-56 fliL N Controls the rotational direction of flagella during chemotaxis
KKDGPOJN_01625 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KKDGPOJN_01626 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KKDGPOJN_01627 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
KKDGPOJN_01628 5e-111 fliZ N Flagellar biosynthesis protein, FliO
KKDGPOJN_01629 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
KKDGPOJN_01630 2e-37 fliQ N Role in flagellar biosynthesis
KKDGPOJN_01631 8.9e-131 fliR N Flagellar biosynthetic protein FliR
KKDGPOJN_01632 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KKDGPOJN_01633 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KKDGPOJN_01634 8.8e-193 flhF N Flagellar biosynthesis regulator FlhF
KKDGPOJN_01635 4.5e-155 flhG D Belongs to the ParA family
KKDGPOJN_01636 1.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KKDGPOJN_01637 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KKDGPOJN_01638 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
KKDGPOJN_01639 3.7e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KKDGPOJN_01640 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KKDGPOJN_01641 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKDGPOJN_01642 5.3e-54 ylxL
KKDGPOJN_01643 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
KKDGPOJN_01644 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KKDGPOJN_01645 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KKDGPOJN_01646 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KKDGPOJN_01647 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KKDGPOJN_01648 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
KKDGPOJN_01649 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KKDGPOJN_01650 1.1e-231 rasP M zinc metalloprotease
KKDGPOJN_01651 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KKDGPOJN_01652 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KKDGPOJN_01653 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
KKDGPOJN_01654 5.4e-206 nusA K Participates in both transcription termination and antitermination
KKDGPOJN_01655 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
KKDGPOJN_01656 1.8e-47 ylxQ J ribosomal protein
KKDGPOJN_01657 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KKDGPOJN_01658 3.9e-44 ylxP S protein conserved in bacteria
KKDGPOJN_01659 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KKDGPOJN_01660 9.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KKDGPOJN_01661 3.9e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KKDGPOJN_01662 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KKDGPOJN_01663 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KKDGPOJN_01664 1.8e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KKDGPOJN_01665 1.5e-233 pepR S Belongs to the peptidase M16 family
KKDGPOJN_01666 2.6e-42 ymxH S YlmC YmxH family
KKDGPOJN_01667 3.6e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KKDGPOJN_01668 5.7e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KKDGPOJN_01669 1.9e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KKDGPOJN_01670 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KKDGPOJN_01671 3.1e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KKDGPOJN_01672 4.4e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KKDGPOJN_01673 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KKDGPOJN_01674 6.3e-31 S YlzJ-like protein
KKDGPOJN_01675 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KKDGPOJN_01676 1.8e-133 ymfC K Transcriptional regulator
KKDGPOJN_01677 1.1e-229 ymfD EGP Major facilitator Superfamily
KKDGPOJN_01678 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
KKDGPOJN_01679 0.0 ydgH S drug exporters of the RND superfamily
KKDGPOJN_01680 1.2e-238 ymfF S Peptidase M16
KKDGPOJN_01681 2.2e-243 ymfH S zinc protease
KKDGPOJN_01682 1.5e-127 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KKDGPOJN_01683 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
KKDGPOJN_01684 1e-142 ymfK S Protein of unknown function (DUF3388)
KKDGPOJN_01685 4.2e-124 ymfM S protein conserved in bacteria
KKDGPOJN_01686 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KKDGPOJN_01687 4.2e-231 cinA 3.5.1.42 S Belongs to the CinA family
KKDGPOJN_01688 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KKDGPOJN_01689 4.3e-193 pbpX V Beta-lactamase
KKDGPOJN_01690 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
KKDGPOJN_01691 4.9e-153 ymdB S protein conserved in bacteria
KKDGPOJN_01692 1.2e-36 spoVS S Stage V sporulation protein S
KKDGPOJN_01693 3.1e-195 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KKDGPOJN_01694 3.9e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KKDGPOJN_01695 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KKDGPOJN_01696 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KKDGPOJN_01697 1.7e-88 cotE S Spore coat protein
KKDGPOJN_01698 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KKDGPOJN_01699 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KKDGPOJN_01700 1.7e-38 L Phage integrase family
KKDGPOJN_01701 2.2e-22
KKDGPOJN_01702 1.5e-32
KKDGPOJN_01705 4.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
KKDGPOJN_01706 9.8e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KKDGPOJN_01707 9.6e-183 pksD Q Acyl transferase domain
KKDGPOJN_01708 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KKDGPOJN_01709 1.6e-33 acpK IQ Phosphopantetheine attachment site
KKDGPOJN_01710 8.2e-243 pksG 2.3.3.10 I synthase
KKDGPOJN_01711 1.2e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
KKDGPOJN_01712 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KKDGPOJN_01713 0.0 rhiB IQ polyketide synthase
KKDGPOJN_01714 0.0 Q Polyketide synthase of type I
KKDGPOJN_01715 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
KKDGPOJN_01716 0.0 dhbF IQ polyketide synthase
KKDGPOJN_01717 0.0 pks13 HQ Beta-ketoacyl synthase
KKDGPOJN_01718 1e-229 cypA C Cytochrome P450
KKDGPOJN_01719 4.9e-78 nucB M Deoxyribonuclease NucA/NucB
KKDGPOJN_01720 6.7e-117 yoaK S Membrane
KKDGPOJN_01721 1.4e-62 ymzB
KKDGPOJN_01722 6.8e-256 aprX O Belongs to the peptidase S8 family
KKDGPOJN_01724 7.8e-126 ymaC S Replication protein
KKDGPOJN_01725 6e-79 ymaD O redox protein, regulator of disulfide bond formation
KKDGPOJN_01726 1.2e-53 ebrB P Small Multidrug Resistance protein
KKDGPOJN_01727 3.1e-48 ebrA P Small Multidrug Resistance protein
KKDGPOJN_01729 1.4e-47 ymaF S YmaF family
KKDGPOJN_01730 6.2e-171 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KKDGPOJN_01731 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KKDGPOJN_01732 2.7e-42
KKDGPOJN_01733 1.8e-20 ymzA
KKDGPOJN_01734 1.7e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KKDGPOJN_01735 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KKDGPOJN_01736 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KKDGPOJN_01737 6.9e-110 ymaB S MutT family
KKDGPOJN_01738 4.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KKDGPOJN_01739 3.9e-176 spoVK O stage V sporulation protein K
KKDGPOJN_01740 1.9e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KKDGPOJN_01741 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KKDGPOJN_01742 1.6e-67 glnR K transcriptional
KKDGPOJN_01743 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
KKDGPOJN_01744 1.7e-30
KKDGPOJN_01745 3.1e-31 S nuclease activity
KKDGPOJN_01748 2.7e-21
KKDGPOJN_01749 1.1e-71 S regulation of transcription, DNA-dependent
KKDGPOJN_01750 6.8e-16 N PFAM YcfA family protein
KKDGPOJN_01752 7.3e-43 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KKDGPOJN_01754 3.3e-35 S Domain of unknown function (DUF4917)
KKDGPOJN_01756 1.1e-251 xynT G MFS/sugar transport protein
KKDGPOJN_01757 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
KKDGPOJN_01758 8.9e-212 xylR GK ROK family
KKDGPOJN_01759 7.1e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KKDGPOJN_01760 6.4e-287 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
KKDGPOJN_01761 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
KKDGPOJN_01765 7e-17
KKDGPOJN_01766 1.7e-120 K WYL domain
KKDGPOJN_01767 7.6e-67 S DinB family
KKDGPOJN_01768 3.3e-186 adhP 1.1.1.1 C alcohol dehydrogenase
KKDGPOJN_01769 1.9e-16
KKDGPOJN_01770 1.5e-19 yoaW
KKDGPOJN_01772 4.1e-141 yoaP 3.1.3.18 K YoaP-like
KKDGPOJN_01773 1.8e-275 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KKDGPOJN_01774 1.8e-51 S SMI1-KNR4 cell-wall
KKDGPOJN_01775 6.5e-51 yokK S SMI1 / KNR4 family
KKDGPOJN_01777 1.4e-33
KKDGPOJN_01780 3.1e-118 ynaE S Domain of unknown function (DUF3885)
KKDGPOJN_01781 1.3e-201 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKDGPOJN_01782 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
KKDGPOJN_01784 1.5e-65 2.3.1.128 J Acetyltransferase (GNAT) domain
KKDGPOJN_01785 5e-23 yvgO
KKDGPOJN_01786 4.6e-94 yvgO
KKDGPOJN_01788 0.0 yobO M Pectate lyase superfamily protein
KKDGPOJN_01789 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KKDGPOJN_01790 2.2e-143 yndL S Replication protein
KKDGPOJN_01792 8e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
KKDGPOJN_01793 3.2e-72 yndM S Protein of unknown function (DUF2512)
KKDGPOJN_01794 7.8e-12 yoaW
KKDGPOJN_01795 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KKDGPOJN_01796 1.4e-50 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KKDGPOJN_01797 3.5e-112 yneB L resolvase
KKDGPOJN_01798 9.8e-33 ynzC S UPF0291 protein
KKDGPOJN_01799 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KKDGPOJN_01800 3.7e-81 yneE S Sporulation inhibitor of replication protein sirA
KKDGPOJN_01801 2.3e-28 yneF S UPF0154 protein
KKDGPOJN_01802 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
KKDGPOJN_01803 1.7e-125 ccdA O cytochrome c biogenesis protein
KKDGPOJN_01804 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KKDGPOJN_01805 1.9e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KKDGPOJN_01806 1.9e-74 yneK S Protein of unknown function (DUF2621)
KKDGPOJN_01807 3.2e-62 hspX O Spore coat protein
KKDGPOJN_01808 2.3e-19 sspP S Belongs to the SspP family
KKDGPOJN_01809 7.5e-15 sspO S Belongs to the SspO family
KKDGPOJN_01810 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KKDGPOJN_01811 9.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KKDGPOJN_01813 4.6e-33 tlp S Belongs to the Tlp family
KKDGPOJN_01814 8.3e-75 yneP S Thioesterase-like superfamily
KKDGPOJN_01815 3.7e-53 yneQ
KKDGPOJN_01816 1.3e-50 yneR S Belongs to the HesB IscA family
KKDGPOJN_01817 1.4e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KKDGPOJN_01818 1.5e-68 yccU S CoA-binding protein
KKDGPOJN_01819 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KKDGPOJN_01820 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KKDGPOJN_01821 6e-13
KKDGPOJN_01822 5.1e-41 ynfC
KKDGPOJN_01823 1.6e-250 agcS E Sodium alanine symporter
KKDGPOJN_01824 2.2e-176 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KKDGPOJN_01825 1.3e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
KKDGPOJN_01826 6.8e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KKDGPOJN_01827 2.9e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
KKDGPOJN_01828 2.3e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KKDGPOJN_01829 3.2e-181 kdgR_1 K transcriptional
KKDGPOJN_01830 7.3e-223 exuT G Sugar (and other) transporter
KKDGPOJN_01831 1.6e-154 yndG S DoxX-like family
KKDGPOJN_01832 2.3e-78 yndH S Domain of unknown function (DUF4166)
KKDGPOJN_01833 4.7e-33 yndJ S YndJ-like protein
KKDGPOJN_01834 7.9e-241 yndJ S YndJ-like protein
KKDGPOJN_01835 8.3e-86
KKDGPOJN_01836 1.5e-64 V ABC transporter
KKDGPOJN_01838 1.4e-11
KKDGPOJN_01839 3.3e-211 S Platelet-activating factor acetylhydrolase, isoform II
KKDGPOJN_01840 1.3e-287 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
KKDGPOJN_01841 1.3e-51 S Domain of unknown function (DUF4870)
KKDGPOJN_01842 7e-235 T PhoQ Sensor
KKDGPOJN_01843 9.9e-129 T Transcriptional regulatory protein, C terminal
KKDGPOJN_01844 1.1e-252 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
KKDGPOJN_01845 2.7e-288 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KKDGPOJN_01846 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKDGPOJN_01847 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKDGPOJN_01848 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKDGPOJN_01849 4.3e-225 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KKDGPOJN_01850 6.9e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KKDGPOJN_01851 7.8e-120 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KKDGPOJN_01852 2.9e-125 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KKDGPOJN_01853 5.9e-253 yxjC EG COG2610 H gluconate symporter and related permeases
KKDGPOJN_01854 2.2e-221 bioI 1.14.14.46 C Cytochrome P450
KKDGPOJN_01855 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KKDGPOJN_01856 2.8e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KKDGPOJN_01857 1.2e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KKDGPOJN_01858 1.7e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KKDGPOJN_01859 6.3e-145 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KKDGPOJN_01860 3.7e-72 yngA S membrane
KKDGPOJN_01861 1.5e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KKDGPOJN_01862 3.2e-104 yngC S SNARE associated Golgi protein
KKDGPOJN_01863 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KKDGPOJN_01864 7.5e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KKDGPOJN_01865 2.5e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KKDGPOJN_01866 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KKDGPOJN_01867 2.1e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KKDGPOJN_01868 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KKDGPOJN_01869 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KKDGPOJN_01870 1.5e-302 yngK T Glycosyl hydrolase-like 10
KKDGPOJN_01871 7.1e-65 yngL S Protein of unknown function (DUF1360)
KKDGPOJN_01872 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
KKDGPOJN_01873 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKDGPOJN_01874 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKDGPOJN_01875 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKDGPOJN_01876 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKDGPOJN_01877 2.6e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KKDGPOJN_01878 1.1e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
KKDGPOJN_01879 7.9e-247 yoeA V MATE efflux family protein
KKDGPOJN_01880 3.8e-96 yoeB S IseA DL-endopeptidase inhibitor
KKDGPOJN_01882 7.7e-97 L Integrase
KKDGPOJN_01883 1.8e-34 yoeD G Helix-turn-helix domain
KKDGPOJN_01884 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KKDGPOJN_01885 1.2e-200 ybcL EGP Major facilitator Superfamily
KKDGPOJN_01886 6.7e-50 ybzH K Helix-turn-helix domain
KKDGPOJN_01887 6.4e-271 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KKDGPOJN_01888 2.9e-154 gltR1 K Transcriptional regulator
KKDGPOJN_01889 9.3e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KKDGPOJN_01890 4.9e-51 1.16.3.1 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KKDGPOJN_01891 5e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KKDGPOJN_01892 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KKDGPOJN_01893 2.2e-149 gltC K Transcriptional regulator
KKDGPOJN_01894 6.2e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KKDGPOJN_01895 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KKDGPOJN_01896 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KKDGPOJN_01897 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KKDGPOJN_01898 4.7e-43 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KKDGPOJN_01899 1.4e-136 yoxB
KKDGPOJN_01900 1.9e-204 yoaB EGP Major facilitator Superfamily
KKDGPOJN_01901 2.6e-272 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
KKDGPOJN_01902 1.4e-192 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KKDGPOJN_01903 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KKDGPOJN_01904 6.3e-26 yoaF
KKDGPOJN_01906 1.6e-97 hpr K helix_turn_helix multiple antibiotic resistance protein
KKDGPOJN_01907 4.3e-43
KKDGPOJN_01908 1.8e-86 S SMI1-KNR4 cell-wall
KKDGPOJN_01909 6.5e-310 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KKDGPOJN_01910 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
KKDGPOJN_01911 2.1e-131 yobQ K helix_turn_helix, arabinose operon control protein
KKDGPOJN_01912 1.7e-94 yobS K Transcriptional regulator
KKDGPOJN_01913 4.5e-137 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
KKDGPOJN_01914 1.9e-92 yobW
KKDGPOJN_01915 1.7e-54 czrA K transcriptional
KKDGPOJN_01916 3.9e-119 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KKDGPOJN_01917 6.9e-90 yozB S membrane
KKDGPOJN_01918 1.5e-138 yocB J Protein required for attachment to host cells
KKDGPOJN_01919 1.6e-93 yocC
KKDGPOJN_01920 6.7e-184 yocD 3.4.17.13 V peptidase S66
KKDGPOJN_01922 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
KKDGPOJN_01923 0.0 recQ 3.6.4.12 L DNA helicase
KKDGPOJN_01924 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KKDGPOJN_01926 2.3e-60 dksA T general stress protein
KKDGPOJN_01927 1e-09 yocL
KKDGPOJN_01928 1.7e-08
KKDGPOJN_01929 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
KKDGPOJN_01930 1.4e-43 yozN
KKDGPOJN_01931 8.5e-37 yocN
KKDGPOJN_01932 2.4e-56 yozO S Bacterial PH domain
KKDGPOJN_01934 1.6e-31 yozC
KKDGPOJN_01935 2.9e-287 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KKDGPOJN_01936 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KKDGPOJN_01937 3.2e-166 sodA 1.15.1.1 P Superoxide dismutase
KKDGPOJN_01938 5.1e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KKDGPOJN_01939 9.3e-162 yocS S -transporter
KKDGPOJN_01940 1.9e-138 S Metallo-beta-lactamase superfamily
KKDGPOJN_01941 7.2e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KKDGPOJN_01942 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KKDGPOJN_01943 0.0 yojO P Von Willebrand factor
KKDGPOJN_01944 3.5e-163 yojN S ATPase family associated with various cellular activities (AAA)
KKDGPOJN_01945 2.1e-108 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KKDGPOJN_01946 2.8e-227 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KKDGPOJN_01947 1.3e-224 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
KKDGPOJN_01948 4.8e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KKDGPOJN_01950 1.3e-241 norM V Multidrug efflux pump
KKDGPOJN_01951 1.2e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KKDGPOJN_01952 2.5e-126 yojG S deacetylase
KKDGPOJN_01953 9.7e-61 yojF S Protein of unknown function (DUF1806)
KKDGPOJN_01954 4.9e-23
KKDGPOJN_01955 9.2e-164 rarD S -transporter
KKDGPOJN_01956 3.3e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
KKDGPOJN_01958 1.6e-67 yodA S tautomerase
KKDGPOJN_01959 1.2e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
KKDGPOJN_01960 3e-56 yodB K transcriptional
KKDGPOJN_01961 4.5e-106 yodC C nitroreductase
KKDGPOJN_01962 3.9e-110 mhqD S Carboxylesterase
KKDGPOJN_01963 6.5e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
KKDGPOJN_01964 1.4e-19 S Protein of unknown function (DUF3311)
KKDGPOJN_01965 3.5e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KKDGPOJN_01966 9.8e-280 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
KKDGPOJN_01967 2.1e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKDGPOJN_01968 2.2e-131 yydK K Transcriptional regulator
KKDGPOJN_01969 1.4e-254 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KKDGPOJN_01970 2.8e-128 yodH Q Methyltransferase
KKDGPOJN_01971 4.3e-34 yodI
KKDGPOJN_01972 8.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KKDGPOJN_01973 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KKDGPOJN_01975 3.3e-55 yodL S YodL-like
KKDGPOJN_01976 4e-102 yodM 3.6.1.27 I Acid phosphatase homologues
KKDGPOJN_01977 6.2e-24 yozD S YozD-like protein
KKDGPOJN_01979 4.9e-125 yodN
KKDGPOJN_01980 6.4e-11 E lactoylglutathione lyase activity
KKDGPOJN_01981 9.1e-36 yozE S Belongs to the UPF0346 family
KKDGPOJN_01982 8.3e-47 yokU S YokU-like protein, putative antitoxin
KKDGPOJN_01983 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
KKDGPOJN_01984 6.6e-159 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
KKDGPOJN_01985 1.6e-254 yodQ 3.5.1.16 E Acetylornithine deacetylase
KKDGPOJN_01986 6.7e-122 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KKDGPOJN_01987 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KKDGPOJN_01988 1.5e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KKDGPOJN_01989 5.4e-64 yosT L Bacterial transcription activator, effector binding domain
KKDGPOJN_01991 8.3e-145 yiiD K acetyltransferase
KKDGPOJN_01992 1.7e-248 cgeD M maturation of the outermost layer of the spore
KKDGPOJN_01993 1.1e-41 cgeC
KKDGPOJN_01994 1.6e-52 cgeA
KKDGPOJN_01995 4.4e-180 cgeB S Spore maturation protein
KKDGPOJN_01996 9.8e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
KKDGPOJN_01997 5.3e-123 4.2.1.115 GM Polysaccharide biosynthesis protein
KKDGPOJN_01998 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KKDGPOJN_01999 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KKDGPOJN_02000 1.4e-66 ypoP K transcriptional
KKDGPOJN_02001 1.6e-97 ypmS S protein conserved in bacteria
KKDGPOJN_02002 4e-136 ypmR E GDSL-like Lipase/Acylhydrolase
KKDGPOJN_02003 8.7e-107 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KKDGPOJN_02004 2.6e-39 ypmP S Protein of unknown function (DUF2535)
KKDGPOJN_02005 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KKDGPOJN_02006 6.1e-177 pspF K Transcriptional regulator
KKDGPOJN_02007 9.3e-110 hlyIII S protein, Hemolysin III
KKDGPOJN_02008 1.4e-115 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KKDGPOJN_02009 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KKDGPOJN_02010 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KKDGPOJN_02011 2.7e-114 ypjP S YpjP-like protein
KKDGPOJN_02012 2.6e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
KKDGPOJN_02013 1e-75 yphP S Belongs to the UPF0403 family
KKDGPOJN_02014 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KKDGPOJN_02015 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
KKDGPOJN_02016 4.5e-98 ypgQ S phosphohydrolase
KKDGPOJN_02017 1.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KKDGPOJN_02018 2.5e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KKDGPOJN_02019 1.5e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KKDGPOJN_02020 1e-30 cspD K Cold-shock protein
KKDGPOJN_02021 3.3e-12 degR
KKDGPOJN_02022 6.1e-36 S Protein of unknown function (DUF2564)
KKDGPOJN_02023 1.5e-28 ypeQ S Zinc-finger
KKDGPOJN_02024 2.4e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
KKDGPOJN_02025 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KKDGPOJN_02026 5.4e-68 rnhA 3.1.26.4 L Ribonuclease
KKDGPOJN_02028 1.4e-164 polA 2.7.7.7 L 5'3' exonuclease
KKDGPOJN_02030 3.5e-39 ypbS S Protein of unknown function (DUF2533)
KKDGPOJN_02031 0.0 ypbR S Dynamin family
KKDGPOJN_02032 1e-87 ypbQ S protein conserved in bacteria
KKDGPOJN_02033 7e-206 bcsA Q Naringenin-chalcone synthase
KKDGPOJN_02034 2.7e-106 J Acetyltransferase (GNAT) domain
KKDGPOJN_02035 6.4e-48 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
KKDGPOJN_02037 1.5e-98 yrdC 3.5.1.19 Q Isochorismatase family
KKDGPOJN_02038 1.8e-232 pbuX F xanthine
KKDGPOJN_02039 1.3e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KKDGPOJN_02040 3e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KKDGPOJN_02041 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
KKDGPOJN_02043 6.6e-22 S YpzG-like protein
KKDGPOJN_02044 4.2e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KKDGPOJN_02045 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KKDGPOJN_02046 2.4e-98 ypsA S Belongs to the UPF0398 family
KKDGPOJN_02047 9.9e-33 cotD S Inner spore coat protein D
KKDGPOJN_02049 2.3e-237 yprB L RNase_H superfamily
KKDGPOJN_02050 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KKDGPOJN_02051 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KKDGPOJN_02052 1.7e-72 hspX O Belongs to the small heat shock protein (HSP20) family
KKDGPOJN_02053 4.5e-45 yppG S YppG-like protein
KKDGPOJN_02055 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
KKDGPOJN_02058 2.4e-186 yppC S Protein of unknown function (DUF2515)
KKDGPOJN_02059 4.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KKDGPOJN_02060 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KKDGPOJN_02061 1.7e-90 ypoC
KKDGPOJN_02062 1.1e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KKDGPOJN_02063 3e-130 dnaD L DNA replication protein DnaD
KKDGPOJN_02064 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
KKDGPOJN_02065 3.3e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KKDGPOJN_02066 9e-81 ypmB S protein conserved in bacteria
KKDGPOJN_02067 6.7e-23 ypmA S Protein of unknown function (DUF4264)
KKDGPOJN_02068 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KKDGPOJN_02069 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KKDGPOJN_02070 5e-159 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KKDGPOJN_02071 7e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KKDGPOJN_02072 1.5e-180 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KKDGPOJN_02073 3.2e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KKDGPOJN_02074 1.8e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KKDGPOJN_02075 5.6e-132 bshB1 S proteins, LmbE homologs
KKDGPOJN_02076 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KKDGPOJN_02077 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KKDGPOJN_02078 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KKDGPOJN_02079 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KKDGPOJN_02080 1e-226 oxdC 4.1.1.2 G Oxalate decarboxylase
KKDGPOJN_02081 7.3e-141 ypjB S sporulation protein
KKDGPOJN_02082 2.1e-103 ypjA S membrane
KKDGPOJN_02083 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KKDGPOJN_02084 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
KKDGPOJN_02085 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
KKDGPOJN_02086 4.7e-76 ypiF S Protein of unknown function (DUF2487)
KKDGPOJN_02087 2.1e-99 ypiB S Belongs to the UPF0302 family
KKDGPOJN_02088 7e-234 S COG0457 FOG TPR repeat
KKDGPOJN_02089 8.4e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KKDGPOJN_02090 2.9e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KKDGPOJN_02091 7.8e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KKDGPOJN_02092 7.2e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KKDGPOJN_02093 4.9e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KKDGPOJN_02094 4.7e-117 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
KKDGPOJN_02095 1.1e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KKDGPOJN_02096 1.2e-159 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KKDGPOJN_02097 1.1e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KKDGPOJN_02098 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KKDGPOJN_02099 3.2e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KKDGPOJN_02100 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KKDGPOJN_02101 1.1e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KKDGPOJN_02102 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KKDGPOJN_02103 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KKDGPOJN_02104 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KKDGPOJN_02105 3.4e-135 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KKDGPOJN_02106 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KKDGPOJN_02107 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
KKDGPOJN_02108 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KKDGPOJN_02109 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KKDGPOJN_02110 3.6e-134 yphF
KKDGPOJN_02111 3.3e-16 yphE S Protein of unknown function (DUF2768)
KKDGPOJN_02112 8.6e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KKDGPOJN_02113 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KKDGPOJN_02114 1.2e-103 yphA
KKDGPOJN_02115 4.7e-08 S YpzI-like protein
KKDGPOJN_02116 4.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KKDGPOJN_02117 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
KKDGPOJN_02118 3.6e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KKDGPOJN_02119 1.4e-12 S Family of unknown function (DUF5359)
KKDGPOJN_02120 1.1e-62 ypfA M Flagellar protein YcgR
KKDGPOJN_02121 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KKDGPOJN_02122 1.6e-160 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KKDGPOJN_02123 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
KKDGPOJN_02124 1e-187 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KKDGPOJN_02125 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KKDGPOJN_02126 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KKDGPOJN_02127 2.8e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
KKDGPOJN_02128 5.7e-85 ypbF S Protein of unknown function (DUF2663)
KKDGPOJN_02129 2.1e-76 ypbE M Lysin motif
KKDGPOJN_02130 9.9e-100 ypbD S metal-dependent membrane protease
KKDGPOJN_02131 4.7e-271 recQ 3.6.4.12 L DNA helicase
KKDGPOJN_02132 2.4e-195 ypbB 5.1.3.1 S protein conserved in bacteria
KKDGPOJN_02133 3.6e-41 fer C Ferredoxin
KKDGPOJN_02134 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KKDGPOJN_02135 2.2e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KKDGPOJN_02136 4.8e-199 rsiX
KKDGPOJN_02137 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
KKDGPOJN_02138 0.0 resE 2.7.13.3 T Histidine kinase
KKDGPOJN_02139 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKDGPOJN_02140 4.2e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KKDGPOJN_02141 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KKDGPOJN_02142 1.1e-98 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KKDGPOJN_02143 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KKDGPOJN_02144 4.9e-88 spmB S Spore maturation protein
KKDGPOJN_02145 2e-103 spmA S Spore maturation protein
KKDGPOJN_02146 1.1e-214 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KKDGPOJN_02147 3.8e-93 ypuI S Protein of unknown function (DUF3907)
KKDGPOJN_02148 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KKDGPOJN_02149 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KKDGPOJN_02151 8.4e-93 ypuF S Domain of unknown function (DUF309)
KKDGPOJN_02152 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KKDGPOJN_02153 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KKDGPOJN_02154 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KKDGPOJN_02155 1e-111 ribE 2.5.1.9 H Riboflavin synthase
KKDGPOJN_02156 1.4e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KKDGPOJN_02157 6.4e-49 ypuD
KKDGPOJN_02158 1.3e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KKDGPOJN_02159 2.4e-81 ccdC1 O Protein of unknown function (DUF1453)
KKDGPOJN_02160 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KKDGPOJN_02161 5.1e-154 ypuA S Secreted protein
KKDGPOJN_02162 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KKDGPOJN_02163 1.2e-269 spoVAF EG Stage V sporulation protein AF
KKDGPOJN_02164 5.2e-110 spoVAEA S stage V sporulation protein
KKDGPOJN_02165 3.8e-57 spoVAEB S stage V sporulation protein
KKDGPOJN_02166 1.4e-189 spoVAD I Stage V sporulation protein AD
KKDGPOJN_02167 1.3e-78 spoVAC S stage V sporulation protein AC
KKDGPOJN_02168 3.9e-60 spoVAB S Stage V sporulation protein AB
KKDGPOJN_02169 4.8e-111 spoVAA S Stage V sporulation protein AA
KKDGPOJN_02170 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKDGPOJN_02171 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KKDGPOJN_02172 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KKDGPOJN_02173 1.1e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KKDGPOJN_02174 4.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KKDGPOJN_02175 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KKDGPOJN_02176 3.7e-165 xerD L recombinase XerD
KKDGPOJN_02177 3.7e-37 S Protein of unknown function (DUF4227)
KKDGPOJN_02178 1.9e-80 fur P Belongs to the Fur family
KKDGPOJN_02179 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KKDGPOJN_02180 1.7e-34 yqkK
KKDGPOJN_02181 5.7e-22
KKDGPOJN_02182 7.7e-244 mleA 1.1.1.38 C malic enzyme
KKDGPOJN_02183 2.7e-239 mleN C Na H antiporter
KKDGPOJN_02184 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
KKDGPOJN_02185 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
KKDGPOJN_02186 1.9e-56 ansR K Transcriptional regulator
KKDGPOJN_02187 4e-220 yqxK 3.6.4.12 L DNA helicase
KKDGPOJN_02188 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KKDGPOJN_02190 1.4e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KKDGPOJN_02192 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KKDGPOJN_02193 3.2e-39 yqkC S Protein of unknown function (DUF2552)
KKDGPOJN_02194 3.8e-60 yqkB S Belongs to the HesB IscA family
KKDGPOJN_02195 6.2e-174 yqkA K GrpB protein
KKDGPOJN_02196 4.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
KKDGPOJN_02197 3.9e-89 yqjY K acetyltransferase
KKDGPOJN_02198 7.2e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KKDGPOJN_02199 7.6e-58 S YolD-like protein
KKDGPOJN_02201 1.5e-184 yueF S transporter activity
KKDGPOJN_02203 2e-70 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KKDGPOJN_02204 1.3e-176 coaA 2.7.1.33 F Pantothenic acid kinase
KKDGPOJN_02205 1.4e-256 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
KKDGPOJN_02206 4.2e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KKDGPOJN_02207 1e-173 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
KKDGPOJN_02208 3.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KKDGPOJN_02209 9.7e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KKDGPOJN_02210 2.9e-240 pksG 2.3.3.10 I synthase
KKDGPOJN_02211 6.8e-220 eryK 1.14.13.154 C Cytochrome P450
KKDGPOJN_02212 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KKDGPOJN_02213 0.0 Q Polyketide synthase of type I
KKDGPOJN_02214 0.0 pfaA Q Polyketide synthase of type I
KKDGPOJN_02215 0.0 pksJ Q Polyketide synthase of type I
KKDGPOJN_02216 0.0 Q Polyketide synthase of type I
KKDGPOJN_02217 0.0 1.1.1.320 Q Polyketide synthase of type I
KKDGPOJN_02218 0.0 pksJ Q Polyketide synthase of type I
KKDGPOJN_02219 1.8e-128 IQ reductase
KKDGPOJN_02220 1.2e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KKDGPOJN_02223 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KKDGPOJN_02224 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
KKDGPOJN_02225 2.4e-164 K LysR substrate binding domain
KKDGPOJN_02226 1.4e-50 S GlpM protein
KKDGPOJN_02227 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KKDGPOJN_02228 1.1e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KKDGPOJN_02229 1.2e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KKDGPOJN_02230 2.5e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KKDGPOJN_02231 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KKDGPOJN_02232 1.9e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KKDGPOJN_02233 3.1e-25 yqzJ
KKDGPOJN_02234 1.3e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KKDGPOJN_02235 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KKDGPOJN_02236 6.3e-290 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KKDGPOJN_02237 4.2e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
KKDGPOJN_02239 3.1e-95 yqjB S protein conserved in bacteria
KKDGPOJN_02240 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
KKDGPOJN_02241 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KKDGPOJN_02242 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
KKDGPOJN_02243 1.2e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
KKDGPOJN_02244 1.7e-75 yqiW S Belongs to the UPF0403 family
KKDGPOJN_02245 7.7e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KKDGPOJN_02246 1.1e-202 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KKDGPOJN_02247 2.3e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KKDGPOJN_02248 8.6e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KKDGPOJN_02249 5.9e-266 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KKDGPOJN_02250 2e-208 buk 2.7.2.7 C Belongs to the acetokinase family
KKDGPOJN_02251 2e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KKDGPOJN_02252 9.5e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
KKDGPOJN_02253 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
KKDGPOJN_02254 7e-34 yqzF S Protein of unknown function (DUF2627)
KKDGPOJN_02255 3.1e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KKDGPOJN_02256 7.5e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KKDGPOJN_02257 1.4e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KKDGPOJN_02258 4.2e-206 mmgC I acyl-CoA dehydrogenase
KKDGPOJN_02259 1.7e-151 hbdA 1.1.1.157 I Dehydrogenase
KKDGPOJN_02260 8.3e-213 mmgA 2.3.1.9 I Belongs to the thiolase family
KKDGPOJN_02261 2.5e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KKDGPOJN_02262 1.4e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
KKDGPOJN_02263 2.5e-17
KKDGPOJN_02264 1.5e-101 ytaF P Probably functions as a manganese efflux pump
KKDGPOJN_02265 1.2e-112 K Protein of unknown function (DUF1232)
KKDGPOJN_02267 6e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KKDGPOJN_02270 2.6e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KKDGPOJN_02271 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KKDGPOJN_02272 2.8e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
KKDGPOJN_02273 1.2e-305 recN L May be involved in recombinational repair of damaged DNA
KKDGPOJN_02274 3.9e-78 argR K Regulates arginine biosynthesis genes
KKDGPOJN_02275 2.5e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KKDGPOJN_02276 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KKDGPOJN_02277 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KKDGPOJN_02278 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KKDGPOJN_02279 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KKDGPOJN_02280 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KKDGPOJN_02281 2.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KKDGPOJN_02282 8.1e-67 yqhY S protein conserved in bacteria
KKDGPOJN_02283 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KKDGPOJN_02284 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KKDGPOJN_02285 2.5e-62 spoIIIAH S SpoIIIAH-like protein
KKDGPOJN_02286 1e-117 spoIIIAG S stage III sporulation protein AG
KKDGPOJN_02287 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
KKDGPOJN_02288 3.1e-199 spoIIIAE S stage III sporulation protein AE
KKDGPOJN_02289 2.5e-41 spoIIIAD S Stage III sporulation protein AD
KKDGPOJN_02290 7.6e-29 spoIIIAC S stage III sporulation protein AC
KKDGPOJN_02291 1.7e-85 spoIIIAB S Stage III sporulation protein
KKDGPOJN_02292 4.2e-172 spoIIIAA S stage III sporulation protein AA
KKDGPOJN_02293 1.8e-36 yqhV S Protein of unknown function (DUF2619)
KKDGPOJN_02294 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KKDGPOJN_02295 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KKDGPOJN_02296 4.9e-88 yqhR S Conserved membrane protein YqhR
KKDGPOJN_02297 1.5e-172 yqhQ S Protein of unknown function (DUF1385)
KKDGPOJN_02298 3.4e-62 yqhP
KKDGPOJN_02299 6.9e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
KKDGPOJN_02300 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KKDGPOJN_02301 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KKDGPOJN_02302 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
KKDGPOJN_02303 1.8e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KKDGPOJN_02304 7.9e-252 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KKDGPOJN_02305 6.3e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KKDGPOJN_02306 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KKDGPOJN_02307 8.4e-153 yqhG S Bacterial protein YqhG of unknown function
KKDGPOJN_02308 1.3e-21 sinI S Anti-repressor SinI
KKDGPOJN_02309 7.8e-55 sinR K transcriptional
KKDGPOJN_02310 3.3e-141 tasA S Cell division protein FtsN
KKDGPOJN_02311 3.5e-71 sipW 3.4.21.89 U Signal peptidase
KKDGPOJN_02312 7.2e-121 yqxM
KKDGPOJN_02313 1.3e-54 yqzG S Protein of unknown function (DUF3889)
KKDGPOJN_02314 2.3e-26 yqzE S YqzE-like protein
KKDGPOJN_02315 2.5e-62 S ComG operon protein 7
KKDGPOJN_02316 5.1e-66 comGF U Putative Competence protein ComGF
KKDGPOJN_02317 3.4e-20 comGE
KKDGPOJN_02318 2.6e-71 gspH NU Tfp pilus assembly protein FimT
KKDGPOJN_02319 7.5e-49 comGC U Required for transformation and DNA binding
KKDGPOJN_02320 5.4e-184 comGB NU COG1459 Type II secretory pathway, component PulF
KKDGPOJN_02321 2.3e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KKDGPOJN_02322 1.5e-185 corA P Mg2 transporter protein
KKDGPOJN_02323 5.7e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KKDGPOJN_02324 1e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KKDGPOJN_02326 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
KKDGPOJN_02327 3.1e-37 yqgY S Protein of unknown function (DUF2626)
KKDGPOJN_02328 3.6e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KKDGPOJN_02329 5.4e-20 yqgW S Protein of unknown function (DUF2759)
KKDGPOJN_02330 6.9e-50 yqgV S Thiamine-binding protein
KKDGPOJN_02331 3e-198 yqgU
KKDGPOJN_02332 3.5e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
KKDGPOJN_02333 4.9e-179 glcK 2.7.1.2 G Glucokinase
KKDGPOJN_02334 4.1e-232 nhaC C Na H antiporter
KKDGPOJN_02335 1.8e-07 yqgO
KKDGPOJN_02336 4.1e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KKDGPOJN_02337 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KKDGPOJN_02338 1.2e-50 yqzD
KKDGPOJN_02339 1.6e-74 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KKDGPOJN_02340 2.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KKDGPOJN_02341 2.3e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KKDGPOJN_02342 1.8e-156 pstA P Phosphate transport system permease
KKDGPOJN_02343 5.2e-154 pstC P probably responsible for the translocation of the substrate across the membrane
KKDGPOJN_02344 1.7e-157 pstS P Phosphate
KKDGPOJN_02345 0.0 pbpA 3.4.16.4 M penicillin-binding protein
KKDGPOJN_02346 2e-228 yqgE EGP Major facilitator superfamily
KKDGPOJN_02347 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KKDGPOJN_02348 3e-76 yqgC S protein conserved in bacteria
KKDGPOJN_02349 8.7e-131 yqgB S Protein of unknown function (DUF1189)
KKDGPOJN_02350 1.1e-47 yqfZ M LysM domain
KKDGPOJN_02351 4.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KKDGPOJN_02352 2.3e-52 yqfX S membrane
KKDGPOJN_02353 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KKDGPOJN_02354 2.9e-72 zur P Belongs to the Fur family
KKDGPOJN_02355 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KKDGPOJN_02356 1.6e-36 yqfT S Protein of unknown function (DUF2624)
KKDGPOJN_02357 4.4e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KKDGPOJN_02358 2e-239 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KKDGPOJN_02359 6.2e-51 yqfQ S YqfQ-like protein
KKDGPOJN_02360 1.9e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KKDGPOJN_02361 2.1e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KKDGPOJN_02362 2.2e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
KKDGPOJN_02363 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
KKDGPOJN_02364 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KKDGPOJN_02365 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KKDGPOJN_02366 6.1e-88 yaiI S Belongs to the UPF0178 family
KKDGPOJN_02367 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KKDGPOJN_02368 4.5e-112 ccpN K CBS domain
KKDGPOJN_02369 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KKDGPOJN_02370 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KKDGPOJN_02371 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
KKDGPOJN_02372 1.8e-16 S YqzL-like protein
KKDGPOJN_02373 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KKDGPOJN_02374 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KKDGPOJN_02375 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KKDGPOJN_02376 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KKDGPOJN_02377 0.0 yqfF S membrane-associated HD superfamily hydrolase
KKDGPOJN_02378 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
KKDGPOJN_02379 2.6e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KKDGPOJN_02380 9.3e-46 yqfC S sporulation protein YqfC
KKDGPOJN_02381 3.8e-54 yqfB
KKDGPOJN_02382 1.2e-119 yqfA S UPF0365 protein
KKDGPOJN_02383 2.2e-230 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
KKDGPOJN_02384 3.6e-68 yqeY S Yqey-like protein
KKDGPOJN_02385 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KKDGPOJN_02386 4.6e-158 yqeW P COG1283 Na phosphate symporter
KKDGPOJN_02387 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KKDGPOJN_02388 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KKDGPOJN_02389 1.3e-173 prmA J Methylates ribosomal protein L11
KKDGPOJN_02390 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KKDGPOJN_02391 0.0 dnaK O Heat shock 70 kDa protein
KKDGPOJN_02392 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KKDGPOJN_02393 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KKDGPOJN_02394 2.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
KKDGPOJN_02395 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KKDGPOJN_02396 3.8e-54 yqxA S Protein of unknown function (DUF3679)
KKDGPOJN_02397 1.4e-220 spoIIP M stage II sporulation protein P
KKDGPOJN_02398 1.5e-203 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KKDGPOJN_02399 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
KKDGPOJN_02400 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
KKDGPOJN_02401 0.0 comEC S Competence protein ComEC
KKDGPOJN_02402 8e-105 comEB 3.5.4.12 F ComE operon protein 2
KKDGPOJN_02403 2.8e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KKDGPOJN_02404 7.1e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KKDGPOJN_02405 6.4e-139 yqeM Q Methyltransferase
KKDGPOJN_02406 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KKDGPOJN_02407 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KKDGPOJN_02408 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KKDGPOJN_02409 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KKDGPOJN_02410 2.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KKDGPOJN_02411 5.9e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KKDGPOJN_02412 2e-94 yqeG S hydrolase of the HAD superfamily
KKDGPOJN_02414 1.1e-138 yqeF E GDSL-like Lipase/Acylhydrolase
KKDGPOJN_02415 2e-140 3.5.1.104 G Polysaccharide deacetylase
KKDGPOJN_02416 1.6e-106 yqeD S SNARE associated Golgi protein
KKDGPOJN_02417 6.9e-218 EGP Major facilitator Superfamily
KKDGPOJN_02418 9.8e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KKDGPOJN_02419 7.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
KKDGPOJN_02420 2.7e-91 K Transcriptional regulator PadR-like family
KKDGPOJN_02421 8.1e-149 ydeE K AraC family transcriptional regulator
KKDGPOJN_02422 9.7e-105 K Transcriptional regulator
KKDGPOJN_02423 1.2e-124 yecA E amino acid
KKDGPOJN_02424 3e-69 psiE S Belongs to the PsiE family
KKDGPOJN_02425 2.1e-233 yrkQ T Histidine kinase
KKDGPOJN_02426 3.2e-124 T Transcriptional regulator
KKDGPOJN_02427 1.3e-221 yrkO P Protein of unknown function (DUF418)
KKDGPOJN_02428 5.6e-103 yrkN K Acetyltransferase (GNAT) family
KKDGPOJN_02429 2e-97 adk 2.7.4.3 F adenylate kinase activity
KKDGPOJN_02430 3.6e-29 yyaR K acetyltransferase
KKDGPOJN_02431 7.3e-221 tetL EGP Major facilitator Superfamily
KKDGPOJN_02432 2.2e-80 yyaR K Acetyltransferase (GNAT) domain
KKDGPOJN_02433 1.5e-91 yrdA S DinB family
KKDGPOJN_02435 2e-146 S hydrolase
KKDGPOJN_02436 1.2e-143 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
KKDGPOJN_02437 1.6e-129 glvR K Helix-turn-helix domain, rpiR family
KKDGPOJN_02438 5.1e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
KKDGPOJN_02439 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
KKDGPOJN_02440 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
KKDGPOJN_02441 1e-181 romA S Beta-lactamase superfamily domain
KKDGPOJN_02442 1.2e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KKDGPOJN_02443 2e-163 yybE K Transcriptional regulator
KKDGPOJN_02444 3.5e-211 ynfM EGP Major facilitator Superfamily
KKDGPOJN_02445 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KKDGPOJN_02446 7.7e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
KKDGPOJN_02447 3.9e-93 yrhH Q methyltransferase
KKDGPOJN_02449 8e-143 focA P Formate nitrite
KKDGPOJN_02450 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
KKDGPOJN_02451 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KKDGPOJN_02452 4.5e-80 yrhD S Protein of unknown function (DUF1641)
KKDGPOJN_02453 4.6e-35 yrhC S YrhC-like protein
KKDGPOJN_02454 1.8e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KKDGPOJN_02455 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KKDGPOJN_02456 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KKDGPOJN_02457 6.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KKDGPOJN_02458 4.1e-27 yrzA S Protein of unknown function (DUF2536)
KKDGPOJN_02459 8.9e-69 yrrS S Protein of unknown function (DUF1510)
KKDGPOJN_02460 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
KKDGPOJN_02461 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KKDGPOJN_02462 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
KKDGPOJN_02463 7.9e-246 yegQ O COG0826 Collagenase and related proteases
KKDGPOJN_02464 1.7e-173 yegQ O Peptidase U32
KKDGPOJN_02465 3.6e-117 yrrM 2.1.1.104 S O-methyltransferase
KKDGPOJN_02466 1.4e-185 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KKDGPOJN_02467 7.1e-46 yrzB S Belongs to the UPF0473 family
KKDGPOJN_02468 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KKDGPOJN_02469 8.5e-41 yrzL S Belongs to the UPF0297 family
KKDGPOJN_02470 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KKDGPOJN_02471 2.4e-163 yrrI S AI-2E family transporter
KKDGPOJN_02472 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KKDGPOJN_02473 7.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
KKDGPOJN_02474 1.2e-109 gluC P ABC transporter
KKDGPOJN_02475 4.4e-107 glnP P ABC transporter
KKDGPOJN_02476 2.1e-08 S Protein of unknown function (DUF3918)
KKDGPOJN_02477 2.9e-30 yrzR
KKDGPOJN_02478 5.3e-83 yrrD S protein conserved in bacteria
KKDGPOJN_02479 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KKDGPOJN_02480 1.7e-18 S COG0457 FOG TPR repeat
KKDGPOJN_02481 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KKDGPOJN_02482 1.8e-212 iscS 2.8.1.7 E Cysteine desulfurase
KKDGPOJN_02483 7.8e-64 cymR K Transcriptional regulator
KKDGPOJN_02484 6.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KKDGPOJN_02485 9.6e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KKDGPOJN_02486 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KKDGPOJN_02487 9.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
KKDGPOJN_02490 9.1e-276 lytH 3.5.1.28 M COG3103 SH3 domain protein
KKDGPOJN_02491 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KKDGPOJN_02492 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KKDGPOJN_02493 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KKDGPOJN_02494 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KKDGPOJN_02495 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
KKDGPOJN_02496 1.2e-85 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
KKDGPOJN_02497 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KKDGPOJN_02498 3.8e-50 yrzD S Post-transcriptional regulator
KKDGPOJN_02499 7.2e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KKDGPOJN_02500 4.7e-109 yrbG S membrane
KKDGPOJN_02501 2.4e-60 yrzE S Protein of unknown function (DUF3792)
KKDGPOJN_02502 5.6e-37 yajC U Preprotein translocase subunit YajC
KKDGPOJN_02503 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KKDGPOJN_02504 3.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KKDGPOJN_02505 1.6e-20 yrzS S Protein of unknown function (DUF2905)
KKDGPOJN_02506 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KKDGPOJN_02507 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KKDGPOJN_02508 3.7e-93 bofC S BofC C-terminal domain
KKDGPOJN_02510 2.3e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KKDGPOJN_02511 8.8e-146 safA M spore coat assembly protein SafA
KKDGPOJN_02512 1.9e-211 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KKDGPOJN_02513 5.3e-153 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KKDGPOJN_02514 6.9e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KKDGPOJN_02515 1.7e-223 nifS 2.8.1.7 E Cysteine desulfurase
KKDGPOJN_02516 5.5e-95 niaR S small molecule binding protein (contains 3H domain)
KKDGPOJN_02517 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
KKDGPOJN_02518 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
KKDGPOJN_02519 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KKDGPOJN_02520 3.3e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KKDGPOJN_02521 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KKDGPOJN_02522 3.2e-56 ysxB J ribosomal protein
KKDGPOJN_02523 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
KKDGPOJN_02524 2.7e-160 spoIVFB S Stage IV sporulation protein
KKDGPOJN_02525 1.9e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KKDGPOJN_02526 2.3e-142 minD D Belongs to the ParA family
KKDGPOJN_02527 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KKDGPOJN_02528 5.4e-84 mreD M shape-determining protein
KKDGPOJN_02529 1.2e-157 mreC M Involved in formation and maintenance of cell shape
KKDGPOJN_02530 4e-184 mreB D Rod shape-determining protein MreB
KKDGPOJN_02531 1.8e-127 radC E Belongs to the UPF0758 family
KKDGPOJN_02532 2.4e-101 maf D septum formation protein Maf
KKDGPOJN_02533 8.7e-139 spoIIB S Sporulation related domain
KKDGPOJN_02534 7.8e-132 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KKDGPOJN_02535 2.1e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KKDGPOJN_02536 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KKDGPOJN_02537 2.1e-25
KKDGPOJN_02538 3.3e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KKDGPOJN_02539 5.2e-222 spoVID M stage VI sporulation protein D
KKDGPOJN_02540 1.8e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KKDGPOJN_02541 1e-184 hemB 4.2.1.24 H Belongs to the ALAD family
KKDGPOJN_02542 1e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KKDGPOJN_02543 9.3e-175 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KKDGPOJN_02544 3.6e-146 hemX O cytochrome C
KKDGPOJN_02545 4.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KKDGPOJN_02546 3.8e-87 ysxD
KKDGPOJN_02547 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
KKDGPOJN_02548 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KKDGPOJN_02549 6e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
KKDGPOJN_02550 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KKDGPOJN_02551 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KKDGPOJN_02552 2.1e-188 ysoA H Tetratricopeptide repeat
KKDGPOJN_02553 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KKDGPOJN_02554 3.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KKDGPOJN_02555 9.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KKDGPOJN_02556 1.8e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KKDGPOJN_02557 1.2e-191 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KKDGPOJN_02558 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
KKDGPOJN_02559 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KKDGPOJN_02562 2.6e-41 pinR3 L Resolvase, N terminal domain
KKDGPOJN_02563 3.8e-12 pinR3 L Resolvase, N terminal domain
KKDGPOJN_02564 3e-92 hsdS 3.1.21.3 V PFAM restriction modification system DNA specificity domain
KKDGPOJN_02565 3.5e-250 hsdM 2.1.1.72 L type I restriction-modification system
KKDGPOJN_02566 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
KKDGPOJN_02568 1.9e-54 L Phage integrase family
KKDGPOJN_02571 4.2e-89 ysnB S Phosphoesterase
KKDGPOJN_02572 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KKDGPOJN_02573 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KKDGPOJN_02574 8.1e-199 gerM S COG5401 Spore germination protein
KKDGPOJN_02575 7.8e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KKDGPOJN_02576 4.8e-73 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
KKDGPOJN_02577 2e-30 gerE K Transcriptional regulator
KKDGPOJN_02578 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
KKDGPOJN_02579 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KKDGPOJN_02580 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KKDGPOJN_02581 4.8e-108 sdhC C succinate dehydrogenase
KKDGPOJN_02582 1.2e-79 yslB S Protein of unknown function (DUF2507)
KKDGPOJN_02583 2.7e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KKDGPOJN_02584 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KKDGPOJN_02585 2.5e-52 trxA O Belongs to the thioredoxin family
KKDGPOJN_02586 1.2e-298 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
KKDGPOJN_02587 1e-176 etfA C Electron transfer flavoprotein
KKDGPOJN_02588 5.7e-138 etfB C Electron transfer flavoprotein
KKDGPOJN_02589 2.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KKDGPOJN_02590 9.2e-104 fadR K Transcriptional regulator
KKDGPOJN_02591 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KKDGPOJN_02592 1.9e-121 ywbB S Protein of unknown function (DUF2711)
KKDGPOJN_02593 4.7e-67 yshE S membrane
KKDGPOJN_02594 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KKDGPOJN_02595 0.0 polX L COG1796 DNA polymerase IV (family X)
KKDGPOJN_02596 2.3e-82 cvpA S membrane protein, required for colicin V production
KKDGPOJN_02597 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KKDGPOJN_02598 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KKDGPOJN_02599 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KKDGPOJN_02600 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KKDGPOJN_02601 1.4e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KKDGPOJN_02602 2e-32 sspI S Belongs to the SspI family
KKDGPOJN_02603 8.4e-204 ysfB KT regulator
KKDGPOJN_02604 3.7e-260 glcD 1.1.3.15 C FAD binding domain
KKDGPOJN_02605 5.7e-255 glcF C Glycolate oxidase
KKDGPOJN_02606 0.0 cstA T Carbon starvation protein
KKDGPOJN_02607 3.6e-298 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
KKDGPOJN_02608 9.9e-144 araQ G transport system permease
KKDGPOJN_02609 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
KKDGPOJN_02610 4.4e-252 araN G carbohydrate transport
KKDGPOJN_02611 9.8e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KKDGPOJN_02612 7.1e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KKDGPOJN_02613 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KKDGPOJN_02614 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
KKDGPOJN_02615 4e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KKDGPOJN_02616 2e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KKDGPOJN_02617 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
KKDGPOJN_02618 1.7e-66 ysdB S Sigma-w pathway protein YsdB
KKDGPOJN_02619 7e-43 ysdA S Membrane
KKDGPOJN_02620 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KKDGPOJN_02621 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KKDGPOJN_02622 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KKDGPOJN_02623 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KKDGPOJN_02624 9.1e-40 lrgA S effector of murein hydrolase LrgA
KKDGPOJN_02625 1.9e-130 lytT T COG3279 Response regulator of the LytR AlgR family
KKDGPOJN_02626 0.0 lytS 2.7.13.3 T Histidine kinase
KKDGPOJN_02627 3.5e-151 ysaA S HAD-hyrolase-like
KKDGPOJN_02628 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KKDGPOJN_02629 1.5e-152 ytxC S YtxC-like family
KKDGPOJN_02630 2.3e-108 ytxB S SNARE associated Golgi protein
KKDGPOJN_02631 4.3e-172 dnaI L Primosomal protein DnaI
KKDGPOJN_02632 2.9e-257 dnaB L Membrane attachment protein
KKDGPOJN_02633 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KKDGPOJN_02634 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KKDGPOJN_02635 8.8e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KKDGPOJN_02636 2e-67 ytcD K Transcriptional regulator
KKDGPOJN_02637 1.7e-205 ytbD EGP Major facilitator Superfamily
KKDGPOJN_02638 6.4e-159 ytbE S reductase
KKDGPOJN_02639 9.9e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KKDGPOJN_02640 2.8e-106 ytaF P Probably functions as a manganese efflux pump
KKDGPOJN_02641 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KKDGPOJN_02642 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KKDGPOJN_02643 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KKDGPOJN_02644 3.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKDGPOJN_02645 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KKDGPOJN_02646 3.1e-242 icd 1.1.1.42 C isocitrate
KKDGPOJN_02647 2.8e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
KKDGPOJN_02649 2.2e-199 S Aspartate phosphatase response regulator
KKDGPOJN_02650 7.1e-53
KKDGPOJN_02651 2.5e-47 yjdF S Protein of unknown function (DUF2992)
KKDGPOJN_02652 1.1e-72 yeaL S membrane
KKDGPOJN_02653 4.8e-194 ytvI S sporulation integral membrane protein YtvI
KKDGPOJN_02654 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
KKDGPOJN_02655 2.2e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KKDGPOJN_02656 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KKDGPOJN_02657 4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KKDGPOJN_02658 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KKDGPOJN_02659 7.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
KKDGPOJN_02660 0.0 dnaE 2.7.7.7 L DNA polymerase
KKDGPOJN_02661 3.2e-56 ytrH S Sporulation protein YtrH
KKDGPOJN_02662 5.1e-87 ytrI
KKDGPOJN_02663 5.8e-23
KKDGPOJN_02664 2.7e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KKDGPOJN_02665 5.3e-47 ytpI S YtpI-like protein
KKDGPOJN_02666 2.8e-238 ytoI K transcriptional regulator containing CBS domains
KKDGPOJN_02667 1.1e-129 ytkL S Belongs to the UPF0173 family
KKDGPOJN_02668 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKDGPOJN_02670 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
KKDGPOJN_02671 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KKDGPOJN_02672 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KKDGPOJN_02673 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KKDGPOJN_02674 1.6e-180 ytxK 2.1.1.72 L DNA methylase
KKDGPOJN_02675 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KKDGPOJN_02676 1.6e-60 ytfJ S Sporulation protein YtfJ
KKDGPOJN_02677 6.5e-109 ytfI S Protein of unknown function (DUF2953)
KKDGPOJN_02678 1.1e-86 yteJ S RDD family
KKDGPOJN_02679 6.4e-182 sppA OU signal peptide peptidase SppA
KKDGPOJN_02680 5.7e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KKDGPOJN_02681 0.0 ytcJ S amidohydrolase
KKDGPOJN_02682 1.1e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KKDGPOJN_02683 3.9e-31 sspB S spore protein
KKDGPOJN_02684 3.9e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KKDGPOJN_02685 1.2e-208 iscS2 2.8.1.7 E Cysteine desulfurase
KKDGPOJN_02686 4e-240 braB E Component of the transport system for branched-chain amino acids
KKDGPOJN_02687 4.7e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KKDGPOJN_02688 2.3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KKDGPOJN_02689 7.7e-109 yttP K Transcriptional regulator
KKDGPOJN_02690 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
KKDGPOJN_02691 3.8e-283 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KKDGPOJN_02692 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KKDGPOJN_02693 7e-256 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KKDGPOJN_02694 5.2e-67 yokH G SMI1 / KNR4 family
KKDGPOJN_02696 1.4e-94 resA 3.1.21.5 L DEAD-like helicases superfamily
KKDGPOJN_02697 5.5e-29 wecC 1.1.1.336 M ArpU family transcriptional regulator
KKDGPOJN_02698 1.5e-22 S Phage-like element PBSX protein XtrA
KKDGPOJN_02699 3.3e-16
KKDGPOJN_02700 3.4e-222 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KKDGPOJN_02701 7.3e-09
KKDGPOJN_02702 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
KKDGPOJN_02704 1.5e-138 E GDSL-like Lipase/Acylhydrolase family
KKDGPOJN_02705 2.5e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KKDGPOJN_02706 4.4e-149 K Transcriptional regulator
KKDGPOJN_02707 2e-124 azlC E AzlC protein
KKDGPOJN_02708 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
KKDGPOJN_02709 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KKDGPOJN_02710 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KKDGPOJN_02711 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KKDGPOJN_02712 2.7e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
KKDGPOJN_02713 5.6e-230 acuC BQ histone deacetylase
KKDGPOJN_02714 3.7e-120 motS N Flagellar motor protein
KKDGPOJN_02715 5.1e-145 motA N flagellar motor
KKDGPOJN_02716 6.4e-182 ccpA K catabolite control protein A
KKDGPOJN_02717 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KKDGPOJN_02718 1.7e-43 ytxJ O Protein of unknown function (DUF2847)
KKDGPOJN_02719 1.7e-16 ytxH S COG4980 Gas vesicle protein
KKDGPOJN_02720 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KKDGPOJN_02721 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KKDGPOJN_02722 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KKDGPOJN_02723 7e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KKDGPOJN_02724 3.7e-148 ytpQ S Belongs to the UPF0354 family
KKDGPOJN_02725 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KKDGPOJN_02726 1.7e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
KKDGPOJN_02727 6.4e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KKDGPOJN_02728 1.7e-51 ytzB S small secreted protein
KKDGPOJN_02729 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
KKDGPOJN_02730 5.1e-164 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KKDGPOJN_02731 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KKDGPOJN_02732 7.8e-45 ytzH S YtzH-like protein
KKDGPOJN_02733 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
KKDGPOJN_02734 1.3e-176 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KKDGPOJN_02735 2.9e-168 ytlQ
KKDGPOJN_02736 1e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KKDGPOJN_02737 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KKDGPOJN_02738 5.1e-270 pepV 3.5.1.18 E Dipeptidase
KKDGPOJN_02739 5.3e-229 pbuO S permease
KKDGPOJN_02740 7.1e-217 ythQ U Bacterial ABC transporter protein EcsB
KKDGPOJN_02741 1.9e-127 ythP V ABC transporter
KKDGPOJN_02742 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KKDGPOJN_02743 8.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KKDGPOJN_02744 7.7e-294 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KKDGPOJN_02745 5.7e-236 ytfP S HI0933-like protein
KKDGPOJN_02746 9.8e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KKDGPOJN_02747 9e-26 yteV S Sporulation protein Cse60
KKDGPOJN_02748 5.7e-186 msmR K Transcriptional regulator
KKDGPOJN_02749 4.9e-243 msmE G Bacterial extracellular solute-binding protein
KKDGPOJN_02750 1.1e-167 amyD G Binding-protein-dependent transport system inner membrane component
KKDGPOJN_02751 1.2e-141 amyC P ABC transporter (permease)
KKDGPOJN_02752 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KKDGPOJN_02753 1.6e-85 M Acetyltransferase (GNAT) domain
KKDGPOJN_02754 1.3e-51 ytwF P Sulfurtransferase
KKDGPOJN_02755 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KKDGPOJN_02756 1.2e-52 ytvB S Protein of unknown function (DUF4257)
KKDGPOJN_02757 8e-138 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KKDGPOJN_02758 4e-207 yttB EGP Major facilitator Superfamily
KKDGPOJN_02759 2.1e-126 ywaF S Integral membrane protein
KKDGPOJN_02760 0.0 bceB V ABC transporter (permease)
KKDGPOJN_02761 9.8e-135 bceA V ABC transporter, ATP-binding protein
KKDGPOJN_02762 8.6e-168 T PhoQ Sensor
KKDGPOJN_02763 9.7e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKDGPOJN_02764 9.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
KKDGPOJN_02765 2.9e-125 ytrE V ABC transporter, ATP-binding protein
KKDGPOJN_02766 1.8e-157
KKDGPOJN_02767 9.1e-165 P ABC-2 family transporter protein
KKDGPOJN_02768 4.2e-170 S ABC-2 family transporter protein
KKDGPOJN_02769 1.9e-161 ytrB P abc transporter atp-binding protein
KKDGPOJN_02770 8.6e-66 ytrA K GntR family transcriptional regulator
KKDGPOJN_02771 1.3e-39 ytzC S Protein of unknown function (DUF2524)
KKDGPOJN_02772 1.4e-189 yhcC S Fe-S oxidoreductase
KKDGPOJN_02773 1.9e-106 ytqB J Putative rRNA methylase
KKDGPOJN_02775 4.7e-143 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
KKDGPOJN_02776 2.4e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KKDGPOJN_02777 1.9e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
KKDGPOJN_02778 1.9e-57 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KKDGPOJN_02779 7.4e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
KKDGPOJN_02780 0.0 asnB 6.3.5.4 E Asparagine synthase
KKDGPOJN_02781 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KKDGPOJN_02782 6.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KKDGPOJN_02783 1.6e-38 ytmB S Protein of unknown function (DUF2584)
KKDGPOJN_02784 7.4e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KKDGPOJN_02785 6.8e-184 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KKDGPOJN_02786 3.5e-143 ytlC P ABC transporter
KKDGPOJN_02787 9e-126 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KKDGPOJN_02788 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KKDGPOJN_02789 1.7e-61 ytkC S Bacteriophage holin family
KKDGPOJN_02790 1.6e-76 dps P Belongs to the Dps family
KKDGPOJN_02792 7.9e-76 ytkA S YtkA-like
KKDGPOJN_02793 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KKDGPOJN_02794 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KKDGPOJN_02795 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KKDGPOJN_02796 7.9e-41 rpmE2 J Ribosomal protein L31
KKDGPOJN_02797 2.6e-239 cydA 1.10.3.14 C oxidase, subunit
KKDGPOJN_02798 5.8e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KKDGPOJN_02799 2.3e-24 S Domain of Unknown Function (DUF1540)
KKDGPOJN_02800 4.1e-124 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KKDGPOJN_02801 1.4e-157 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KKDGPOJN_02802 3.3e-122 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KKDGPOJN_02803 2e-122 troA P Belongs to the bacterial solute-binding protein 9 family
KKDGPOJN_02804 1e-212 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KKDGPOJN_02805 1.1e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KKDGPOJN_02806 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KKDGPOJN_02807 7.9e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KKDGPOJN_02808 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KKDGPOJN_02809 2.1e-271 menF 5.4.4.2 HQ Isochorismate synthase
KKDGPOJN_02810 1.7e-131 dksA T COG1734 DnaK suppressor protein
KKDGPOJN_02811 1.7e-76 tspO T membrane
KKDGPOJN_02820 7.8e-08
KKDGPOJN_02821 1.3e-09
KKDGPOJN_02828 1.6e-08
KKDGPOJN_02833 3.4e-39 S COG NOG14552 non supervised orthologous group
KKDGPOJN_02834 9.7e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
KKDGPOJN_02835 1.3e-178 yuaG 3.4.21.72 S protein conserved in bacteria
KKDGPOJN_02836 5.6e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KKDGPOJN_02837 7.6e-80 yuaE S DinB superfamily
KKDGPOJN_02838 6e-108 yuaD S MOSC domain
KKDGPOJN_02839 1.6e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
KKDGPOJN_02840 5.5e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KKDGPOJN_02841 1.5e-95 yuaC K Belongs to the GbsR family
KKDGPOJN_02842 3.3e-92 yuaB
KKDGPOJN_02843 5.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
KKDGPOJN_02844 4.8e-146 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KKDGPOJN_02845 7.7e-219 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KKDGPOJN_02846 6.2e-122 G Cupin
KKDGPOJN_02847 3.7e-51 yjcN
KKDGPOJN_02849 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KKDGPOJN_02850 4.9e-194 yubA S transporter activity
KKDGPOJN_02851 2.1e-185 ygjR S Oxidoreductase
KKDGPOJN_02852 4.3e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KKDGPOJN_02853 5.3e-236 mcpA NT chemotaxis protein
KKDGPOJN_02854 1.3e-223 mcpA NT chemotaxis protein
KKDGPOJN_02855 1.8e-236 mcpA NT chemotaxis protein
KKDGPOJN_02856 8.1e-221 mcpA NT chemotaxis protein
KKDGPOJN_02857 6.4e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
KKDGPOJN_02858 1.8e-40
KKDGPOJN_02859 1.5e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KKDGPOJN_02860 3.1e-77 yugU S Uncharacterised protein family UPF0047
KKDGPOJN_02861 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KKDGPOJN_02862 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
KKDGPOJN_02863 8.3e-117 yugP S Zn-dependent protease
KKDGPOJN_02864 1e-17
KKDGPOJN_02865 1.1e-26 mstX S Membrane-integrating protein Mistic
KKDGPOJN_02866 1.2e-180 yugO P COG1226 Kef-type K transport systems
KKDGPOJN_02867 2.4e-71 yugN S YugN-like family
KKDGPOJN_02869 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
KKDGPOJN_02870 5.7e-95 S NADPH-dependent FMN reductase
KKDGPOJN_02871 1.4e-118 ycaC Q Isochorismatase family
KKDGPOJN_02872 7.4e-230 yugK C Dehydrogenase
KKDGPOJN_02873 8.4e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KKDGPOJN_02874 1.8e-34 yuzA S Domain of unknown function (DUF378)
KKDGPOJN_02875 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KKDGPOJN_02876 1.2e-208 yugH 2.6.1.1 E Aminotransferase
KKDGPOJN_02877 2e-83 alaR K Transcriptional regulator
KKDGPOJN_02878 1.1e-155 yugF I Hydrolase
KKDGPOJN_02879 2.7e-39 yugE S Domain of unknown function (DUF1871)
KKDGPOJN_02880 1.2e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KKDGPOJN_02881 8.1e-230 T PhoQ Sensor
KKDGPOJN_02882 3.4e-67 kapB G Kinase associated protein B
KKDGPOJN_02883 4e-118 kapD L the KinA pathway to sporulation
KKDGPOJN_02884 2e-185 yuxJ EGP Major facilitator Superfamily
KKDGPOJN_02885 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
KKDGPOJN_02886 5e-72 yuxK S protein conserved in bacteria
KKDGPOJN_02887 9.3e-74 yufK S Family of unknown function (DUF5366)
KKDGPOJN_02888 1.7e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KKDGPOJN_02889 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
KKDGPOJN_02890 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KKDGPOJN_02891 5e-287 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KKDGPOJN_02892 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
KKDGPOJN_02893 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
KKDGPOJN_02894 2.6e-11
KKDGPOJN_02895 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KKDGPOJN_02896 9.2e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KKDGPOJN_02897 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KKDGPOJN_02898 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KKDGPOJN_02899 1.3e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KKDGPOJN_02900 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KKDGPOJN_02901 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
KKDGPOJN_02902 1.6e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
KKDGPOJN_02903 3.4e-112 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KKDGPOJN_02904 1.5e-250 comP 2.7.13.3 T Histidine kinase
KKDGPOJN_02906 3.7e-61 comQ H Polyprenyl synthetase
KKDGPOJN_02908 9.5e-53 yuzC
KKDGPOJN_02909 2e-230 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
KKDGPOJN_02910 2.5e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KKDGPOJN_02911 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
KKDGPOJN_02912 7.2e-68 yueI S Protein of unknown function (DUF1694)
KKDGPOJN_02913 2.8e-38 yueH S YueH-like protein
KKDGPOJN_02914 9.3e-33 yueG S Spore germination protein gerPA/gerPF
KKDGPOJN_02915 7.3e-187 yueF S transporter activity
KKDGPOJN_02916 3.5e-22 S Protein of unknown function (DUF2642)
KKDGPOJN_02917 3.7e-96 yueE S phosphohydrolase
KKDGPOJN_02918 1.9e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKDGPOJN_02919 6.5e-76 yueC S Family of unknown function (DUF5383)
KKDGPOJN_02920 0.0 esaA S type VII secretion protein EsaA
KKDGPOJN_02921 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KKDGPOJN_02922 8.1e-206 essB S WXG100 protein secretion system (Wss), protein YukC
KKDGPOJN_02923 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
KKDGPOJN_02924 3.3e-46 esxA S Belongs to the WXG100 family
KKDGPOJN_02925 3.2e-228 yukF QT Transcriptional regulator
KKDGPOJN_02926 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KKDGPOJN_02927 2.8e-133 yukJ S Uncharacterized conserved protein (DUF2278)
KKDGPOJN_02928 2.1e-34 mbtH S MbtH-like protein
KKDGPOJN_02929 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKDGPOJN_02930 1e-173 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
KKDGPOJN_02931 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
KKDGPOJN_02932 9.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
KKDGPOJN_02933 4.6e-135 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KKDGPOJN_02934 1.5e-163 besA S Putative esterase
KKDGPOJN_02935 4.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
KKDGPOJN_02936 4.3e-101 bioY S Biotin biosynthesis protein
KKDGPOJN_02937 2.4e-208 yuiF S antiporter
KKDGPOJN_02938 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KKDGPOJN_02939 1.2e-77 yuiD S protein conserved in bacteria
KKDGPOJN_02940 1.8e-116 yuiC S protein conserved in bacteria
KKDGPOJN_02941 9.9e-28 yuiB S Putative membrane protein
KKDGPOJN_02942 7.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
KKDGPOJN_02943 1.5e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
KKDGPOJN_02945 1.8e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KKDGPOJN_02946 4.8e-29
KKDGPOJN_02947 2.6e-70 CP Membrane
KKDGPOJN_02948 3.1e-122 V ABC transporter
KKDGPOJN_02950 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
KKDGPOJN_02952 2.1e-94 rimJ 2.3.1.128 J Alanine acetyltransferase
KKDGPOJN_02953 4.8e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
KKDGPOJN_02954 1.1e-62 erpA S Belongs to the HesB IscA family
KKDGPOJN_02955 1.6e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KKDGPOJN_02956 3.8e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KKDGPOJN_02957 2.4e-39 yuzB S Belongs to the UPF0349 family
KKDGPOJN_02958 9.4e-208 yutJ 1.6.99.3 C NADH dehydrogenase
KKDGPOJN_02959 1.7e-54 yuzD S protein conserved in bacteria
KKDGPOJN_02960 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
KKDGPOJN_02961 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
KKDGPOJN_02962 2.6e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KKDGPOJN_02963 2.2e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KKDGPOJN_02964 3.5e-241 hom 1.1.1.3 E homoserine dehydrogenase
KKDGPOJN_02965 1.2e-196 yutH S Spore coat protein
KKDGPOJN_02966 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KKDGPOJN_02967 6.1e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KKDGPOJN_02968 2.1e-73 yutE S Protein of unknown function DUF86
KKDGPOJN_02969 1.7e-47 yutD S protein conserved in bacteria
KKDGPOJN_02970 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KKDGPOJN_02971 1.1e-194 lytH M Peptidase, M23
KKDGPOJN_02972 4.8e-129 yunB S Sporulation protein YunB (Spo_YunB)
KKDGPOJN_02973 1.3e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KKDGPOJN_02974 1.8e-145 yunE S membrane transporter protein
KKDGPOJN_02975 3.1e-169 yunF S Protein of unknown function DUF72
KKDGPOJN_02976 1.5e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
KKDGPOJN_02977 4.1e-264 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KKDGPOJN_02978 8.8e-234 pucR QT COG2508 Regulator of polyketide synthase expression
KKDGPOJN_02979 2.2e-54 pucR QT COG2508 Regulator of polyketide synthase expression
KKDGPOJN_02982 1.1e-129 S Aspartate phosphatase response regulator
KKDGPOJN_02983 4e-71
KKDGPOJN_02984 2.9e-213 blt EGP Major facilitator Superfamily
KKDGPOJN_02985 2.5e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KKDGPOJN_02986 1.1e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KKDGPOJN_02987 4.6e-168 bsn L Ribonuclease
KKDGPOJN_02988 1e-204 msmX P Belongs to the ABC transporter superfamily
KKDGPOJN_02989 1.5e-132 yurK K UTRA
KKDGPOJN_02990 1.8e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
KKDGPOJN_02991 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
KKDGPOJN_02992 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
KKDGPOJN_02993 3.1e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
KKDGPOJN_02994 2e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KKDGPOJN_02996 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
KKDGPOJN_02997 1.1e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KKDGPOJN_02998 4.7e-51 Q ubiE/COQ5 methyltransferase family
KKDGPOJN_02999 9.1e-22 Q ubiE/COQ5 methyltransferase family
KKDGPOJN_03000 9.9e-29 yncE S Protein of unknown function (DUF2691)
KKDGPOJN_03001 3.9e-24 yncE S Protein of unknown function (DUF2691)
KKDGPOJN_03002 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KKDGPOJN_03003 3e-270 sufB O FeS cluster assembly
KKDGPOJN_03004 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KKDGPOJN_03005 4.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KKDGPOJN_03006 1.2e-244 sufD O assembly protein SufD
KKDGPOJN_03007 5.1e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KKDGPOJN_03008 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KKDGPOJN_03009 1.1e-144 metQ P Belongs to the NlpA lipoprotein family
KKDGPOJN_03010 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
KKDGPOJN_03011 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KKDGPOJN_03012 5e-57 yusD S SCP-2 sterol transfer family
KKDGPOJN_03013 1.6e-54 yusE CO Thioredoxin
KKDGPOJN_03014 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
KKDGPOJN_03015 3.7e-40 yusG S Protein of unknown function (DUF2553)
KKDGPOJN_03016 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KKDGPOJN_03017 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KKDGPOJN_03018 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KKDGPOJN_03019 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
KKDGPOJN_03020 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KKDGPOJN_03021 4e-167 fadM E Proline dehydrogenase
KKDGPOJN_03022 3.9e-43
KKDGPOJN_03023 4.2e-53 yusN M Coat F domain
KKDGPOJN_03024 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
KKDGPOJN_03025 8.1e-288 yusP P Major facilitator superfamily
KKDGPOJN_03026 3.7e-157 ywbI2 K Transcriptional regulator
KKDGPOJN_03027 1e-136 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
KKDGPOJN_03028 3.3e-189 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KKDGPOJN_03029 3.3e-39 yusU S Protein of unknown function (DUF2573)
KKDGPOJN_03030 3.1e-150 yusV 3.6.3.34 HP ABC transporter
KKDGPOJN_03031 3.9e-43 S YusW-like protein
KKDGPOJN_03032 0.0 pepF2 E COG1164 Oligoendopeptidase F
KKDGPOJN_03033 5.4e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KKDGPOJN_03034 1.6e-79 dps P Belongs to the Dps family
KKDGPOJN_03035 2.5e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KKDGPOJN_03036 3.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKDGPOJN_03037 2.5e-250 cssS 2.7.13.3 T PhoQ Sensor
KKDGPOJN_03038 1.3e-23
KKDGPOJN_03039 3.6e-157 yuxN K Transcriptional regulator
KKDGPOJN_03040 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KKDGPOJN_03041 6.6e-24 S Protein of unknown function (DUF3970)
KKDGPOJN_03042 1e-257 gerAA EG Spore germination protein
KKDGPOJN_03043 6.6e-188 gerAB E Spore germination protein
KKDGPOJN_03044 6.4e-207 gerAC S Spore germination B3/ GerAC like, C-terminal
KKDGPOJN_03045 9.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KKDGPOJN_03046 4.3e-192 vraS 2.7.13.3 T Histidine kinase
KKDGPOJN_03047 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
KKDGPOJN_03048 4e-140 liaG S Putative adhesin
KKDGPOJN_03049 3.4e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KKDGPOJN_03050 3.3e-46 liaI S membrane
KKDGPOJN_03051 1.4e-226 yvqJ EGP Major facilitator Superfamily
KKDGPOJN_03052 2.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
KKDGPOJN_03053 6.3e-224 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KKDGPOJN_03054 4e-179 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKDGPOJN_03055 1.1e-167 yvrC P ABC transporter substrate-binding protein
KKDGPOJN_03056 1.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KKDGPOJN_03057 1.1e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
KKDGPOJN_03058 0.0 T PhoQ Sensor
KKDGPOJN_03059 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKDGPOJN_03060 1.2e-35
KKDGPOJN_03061 2.9e-102 yvrI K RNA polymerase
KKDGPOJN_03062 1.2e-15 S YvrJ protein family
KKDGPOJN_03063 9.2e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
KKDGPOJN_03064 7.1e-66 yvrL S Regulatory protein YrvL
KKDGPOJN_03065 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
KKDGPOJN_03066 4e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKDGPOJN_03067 6.6e-185 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKDGPOJN_03068 8.9e-178 fhuD P ABC transporter
KKDGPOJN_03069 7.2e-124 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KKDGPOJN_03070 2.9e-236 yvsH E Arginine ornithine antiporter
KKDGPOJN_03071 3.6e-14 S Small spore protein J (Spore_SspJ)
KKDGPOJN_03072 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
KKDGPOJN_03073 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KKDGPOJN_03074 1.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
KKDGPOJN_03075 1.4e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
KKDGPOJN_03076 2.3e-94 modB P COG4149 ABC-type molybdate transport system, permease component
KKDGPOJN_03077 1.5e-112 yfiK K Regulator
KKDGPOJN_03078 5.1e-180 T Histidine kinase
KKDGPOJN_03079 3.6e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
KKDGPOJN_03080 6.7e-193 yfiM V ABC-2 type transporter
KKDGPOJN_03081 6.4e-194 yfiN V COG0842 ABC-type multidrug transport system, permease component
KKDGPOJN_03082 5e-156 yvgN S reductase
KKDGPOJN_03083 1.1e-86 yvgO
KKDGPOJN_03084 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KKDGPOJN_03085 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KKDGPOJN_03086 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KKDGPOJN_03087 0.0 helD 3.6.4.12 L DNA helicase
KKDGPOJN_03088 3.1e-99 yvgT S membrane
KKDGPOJN_03089 1.2e-141 S Metallo-peptidase family M12
KKDGPOJN_03090 5.6e-71 bdbC O Required for disulfide bond formation in some proteins
KKDGPOJN_03091 1.2e-102 bdbD O Thioredoxin
KKDGPOJN_03092 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KKDGPOJN_03093 0.0 copA 3.6.3.54 P P-type ATPase
KKDGPOJN_03094 3.4e-29 copZ P Heavy-metal-associated domain
KKDGPOJN_03095 3.7e-48 csoR S transcriptional
KKDGPOJN_03096 3.4e-194 yvaA 1.1.1.371 S Oxidoreductase
KKDGPOJN_03097 1.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KKDGPOJN_03098 1.8e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKDGPOJN_03099 1.6e-45 ytnI O COG0695 Glutaredoxin and related proteins
KKDGPOJN_03100 4.6e-180 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKDGPOJN_03101 6.2e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KKDGPOJN_03102 1.6e-118 tcyM U Binding-protein-dependent transport system inner membrane component
KKDGPOJN_03103 5.9e-121 tcyL P Binding-protein-dependent transport system inner membrane component
KKDGPOJN_03104 4.9e-148 tcyK M Bacterial periplasmic substrate-binding proteins
KKDGPOJN_03105 4.2e-131 ytmJ ET Bacterial periplasmic substrate-binding proteins
KKDGPOJN_03106 6.6e-101 ytmI K Acetyltransferase (GNAT) domain
KKDGPOJN_03107 2.1e-160 ytlI K LysR substrate binding domain
KKDGPOJN_03108 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KKDGPOJN_03109 2.7e-46 yrdF K ribonuclease inhibitor
KKDGPOJN_03111 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KKDGPOJN_03112 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KKDGPOJN_03113 7.4e-143 est 3.1.1.1 S Carboxylesterase
KKDGPOJN_03114 4.8e-24 secG U Preprotein translocase subunit SecG
KKDGPOJN_03115 5.1e-34 yvzC K Transcriptional
KKDGPOJN_03116 1.8e-69 K transcriptional
KKDGPOJN_03117 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
KKDGPOJN_03118 4.4e-52 yodB K transcriptional
KKDGPOJN_03119 1.7e-257 T His Kinase A (phosphoacceptor) domain
KKDGPOJN_03120 1.4e-121 K Transcriptional regulatory protein, C terminal
KKDGPOJN_03121 8.2e-137 mutG S ABC-2 family transporter protein
KKDGPOJN_03122 7.9e-121 spaE S ABC-2 family transporter protein
KKDGPOJN_03123 1.3e-125 mutF V ABC transporter, ATP-binding protein
KKDGPOJN_03124 4.7e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KKDGPOJN_03125 2.7e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KKDGPOJN_03126 1.6e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KKDGPOJN_03127 1.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KKDGPOJN_03128 4.3e-76 yvbF K Belongs to the GbsR family
KKDGPOJN_03129 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KKDGPOJN_03130 1e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KKDGPOJN_03131 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KKDGPOJN_03132 3.3e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KKDGPOJN_03133 7.1e-98 yvbF K Belongs to the GbsR family
KKDGPOJN_03134 5.2e-105 yvbG U UPF0056 membrane protein
KKDGPOJN_03135 7.6e-121 exoY M Membrane
KKDGPOJN_03136 0.0 tcaA S response to antibiotic
KKDGPOJN_03137 3e-70 yvbK 3.1.3.25 K acetyltransferase
KKDGPOJN_03138 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KKDGPOJN_03139 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KKDGPOJN_03140 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KKDGPOJN_03141 1.9e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KKDGPOJN_03142 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KKDGPOJN_03143 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KKDGPOJN_03145 7.4e-253 araE EGP Major facilitator Superfamily
KKDGPOJN_03146 1.3e-204 araR K transcriptional
KKDGPOJN_03147 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKDGPOJN_03148 2.2e-125 yvbU K Transcriptional regulator
KKDGPOJN_03149 7.7e-158 yvbV EG EamA-like transporter family
KKDGPOJN_03150 8.5e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
KKDGPOJN_03152 5.5e-150 ybbH_1 K RpiR family transcriptional regulator
KKDGPOJN_03153 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
KKDGPOJN_03154 5.2e-224 gntP EG COG2610 H gluconate symporter and related permeases
KKDGPOJN_03155 6.7e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KKDGPOJN_03156 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KKDGPOJN_03157 9.3e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KKDGPOJN_03158 1.3e-221 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KKDGPOJN_03159 3e-120 yvfI K COG2186 Transcriptional regulators
KKDGPOJN_03160 5e-304 yvfH C L-lactate permease
KKDGPOJN_03161 1.1e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KKDGPOJN_03162 2.7e-32 yvfG S YvfG protein
KKDGPOJN_03163 3.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
KKDGPOJN_03164 1.4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KKDGPOJN_03165 3.9e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
KKDGPOJN_03166 6.3e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KKDGPOJN_03167 4.5e-272 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KKDGPOJN_03168 1.2e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KKDGPOJN_03169 1.3e-201 epsI GM pyruvyl transferase
KKDGPOJN_03170 2.4e-192 epsH GT2 S Glycosyltransferase like family 2
KKDGPOJN_03171 3.5e-205 epsG S EpsG family
KKDGPOJN_03172 3e-212 epsF GT4 M Glycosyl transferases group 1
KKDGPOJN_03173 6.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KKDGPOJN_03174 1.7e-218 epsD GT4 M Glycosyl transferase 4-like
KKDGPOJN_03175 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
KKDGPOJN_03176 2.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
KKDGPOJN_03177 2.7e-118 ywqC M biosynthesis protein
KKDGPOJN_03178 5.1e-78 slr K transcriptional
KKDGPOJN_03179 9.3e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KKDGPOJN_03181 9.8e-97 ywjB H RibD C-terminal domain
KKDGPOJN_03182 1.5e-112 yyaS S Membrane
KKDGPOJN_03183 2.4e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KKDGPOJN_03184 1.6e-93 padC Q Phenolic acid decarboxylase
KKDGPOJN_03185 1e-33 MA20_18690 S Protein of unknown function (DUF3237)
KKDGPOJN_03186 6.6e-15 S Protein of unknown function (DUF1433)
KKDGPOJN_03187 6.1e-31 S Protein of unknown function (DUF1433)
KKDGPOJN_03188 1.3e-17 S Protein of unknown function (DUF1433)
KKDGPOJN_03189 5.4e-16 S Protein of unknown function (DUF1433)
KKDGPOJN_03190 8.9e-262 I Pfam Lipase (class 3)
KKDGPOJN_03191 1.8e-34
KKDGPOJN_03193 4.4e-296 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
KKDGPOJN_03194 4.7e-219 rafB P LacY proton/sugar symporter
KKDGPOJN_03195 1.7e-184 scrR K transcriptional
KKDGPOJN_03196 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KKDGPOJN_03197 2.2e-96 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KKDGPOJN_03198 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KKDGPOJN_03199 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KKDGPOJN_03200 5.8e-102 malA S Protein of unknown function (DUF1189)
KKDGPOJN_03201 3.9e-140 malD P transport
KKDGPOJN_03202 7e-221 malC P COG1175 ABC-type sugar transport systems, permease components
KKDGPOJN_03203 1.2e-206 mdxE G COG2182 Maltose-binding periplasmic proteins domains
KKDGPOJN_03204 4.9e-311 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
KKDGPOJN_03205 1.6e-161 yvdE K Transcriptional regulator
KKDGPOJN_03206 3.4e-103 yvdD 3.2.2.10 S Belongs to the LOG family
KKDGPOJN_03207 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
KKDGPOJN_03208 1.6e-280 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
KKDGPOJN_03209 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KKDGPOJN_03210 1.5e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KKDGPOJN_03211 1.6e-79 M Ribonuclease
KKDGPOJN_03212 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
KKDGPOJN_03213 1.2e-36 crh G Phosphocarrier protein Chr
KKDGPOJN_03214 7e-170 whiA K May be required for sporulation
KKDGPOJN_03215 2.2e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KKDGPOJN_03216 1.1e-166 rapZ S Displays ATPase and GTPase activities
KKDGPOJN_03217 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KKDGPOJN_03218 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KKDGPOJN_03219 1.1e-123 usp CBM50 M protein conserved in bacteria
KKDGPOJN_03220 1.8e-273 S COG0457 FOG TPR repeat
KKDGPOJN_03221 8e-191 sasA T Histidine kinase
KKDGPOJN_03222 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKDGPOJN_03223 0.0 msbA2 3.6.3.44 V ABC transporter
KKDGPOJN_03224 8.1e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KKDGPOJN_03225 1.8e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KKDGPOJN_03226 3.2e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KKDGPOJN_03227 8.1e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KKDGPOJN_03228 4.4e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KKDGPOJN_03229 1.5e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KKDGPOJN_03230 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KKDGPOJN_03231 1e-207 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KKDGPOJN_03232 1.2e-137 yvpB NU protein conserved in bacteria
KKDGPOJN_03233 1.2e-83 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KKDGPOJN_03234 2.4e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KKDGPOJN_03235 2.6e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KKDGPOJN_03236 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KKDGPOJN_03237 2.3e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KKDGPOJN_03238 3.6e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KKDGPOJN_03239 1.1e-133 yvoA K transcriptional
KKDGPOJN_03240 4.7e-105 yxaF K Transcriptional regulator
KKDGPOJN_03241 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
KKDGPOJN_03242 1.5e-40 yvlD S Membrane
KKDGPOJN_03243 9.6e-26 pspB KT PspC domain
KKDGPOJN_03244 4.6e-165 yvlB S Putative adhesin
KKDGPOJN_03245 6.1e-49 yvlA
KKDGPOJN_03246 2.2e-32 yvkN
KKDGPOJN_03247 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KKDGPOJN_03248 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KKDGPOJN_03249 7.6e-33 csbA S protein conserved in bacteria
KKDGPOJN_03250 0.0 yvkC 2.7.9.2 GT Phosphotransferase
KKDGPOJN_03251 1.6e-109 yvkB K Transcriptional regulator
KKDGPOJN_03252 5.6e-226 yvkA EGP Major facilitator Superfamily
KKDGPOJN_03253 5.5e-27 bacT Q Thioesterase domain
KKDGPOJN_03255 9.5e-176 S Psort location CytoplasmicMembrane, score
KKDGPOJN_03256 3.3e-51 E Saccharopine dehydrogenase
KKDGPOJN_03257 1.5e-98 V ABC transporter transmembrane region
KKDGPOJN_03258 0.0 Q TIGRFAM amino acid adenylation domain
KKDGPOJN_03259 0.0 fusAA Q Non-ribosomal peptide synthetase modules and related proteins
KKDGPOJN_03260 5.8e-65 IQ KR domain
KKDGPOJN_03262 8.6e-20 L Transposase and inactivated derivatives
KKDGPOJN_03263 1.2e-219 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KKDGPOJN_03264 1.5e-55 swrA S Swarming motility protein
KKDGPOJN_03265 6.1e-255 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KKDGPOJN_03266 4.4e-229 ywoF P Right handed beta helix region
KKDGPOJN_03267 9.2e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KKDGPOJN_03268 1e-122 ftsE D cell division ATP-binding protein FtsE
KKDGPOJN_03269 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
KKDGPOJN_03270 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KKDGPOJN_03271 5.1e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KKDGPOJN_03272 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KKDGPOJN_03273 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KKDGPOJN_03274 6.8e-68
KKDGPOJN_03275 2.6e-10 fliT S bacterial-type flagellum organization
KKDGPOJN_03276 3e-66 fliS N flagellar protein FliS
KKDGPOJN_03277 3.6e-245 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KKDGPOJN_03278 2.1e-100 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KKDGPOJN_03279 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KKDGPOJN_03280 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KKDGPOJN_03281 3.4e-79 yviE
KKDGPOJN_03282 6.1e-163 flgL N Belongs to the bacterial flagellin family
KKDGPOJN_03283 2.8e-274 flgK N flagellar hook-associated protein
KKDGPOJN_03284 8.9e-81 flgN NOU FlgN protein
KKDGPOJN_03285 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
KKDGPOJN_03286 2.4e-74 yvyF S flagellar protein
KKDGPOJN_03287 4.5e-77 comFC S Phosphoribosyl transferase domain
KKDGPOJN_03288 1.7e-42 comFB S Late competence development protein ComFB
KKDGPOJN_03289 1.6e-260 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KKDGPOJN_03290 7.1e-158 degV S protein conserved in bacteria
KKDGPOJN_03291 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KKDGPOJN_03292 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KKDGPOJN_03293 7.7e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KKDGPOJN_03294 7.8e-166 yvhJ K Transcriptional regulator
KKDGPOJN_03295 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KKDGPOJN_03296 8.3e-237 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
KKDGPOJN_03297 1.5e-143 tuaG GT2 M Glycosyltransferase like family 2
KKDGPOJN_03298 1.2e-115 tuaF M protein involved in exopolysaccharide biosynthesis
KKDGPOJN_03299 1e-257 tuaE M Teichuronic acid biosynthesis protein
KKDGPOJN_03300 1.4e-248 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KKDGPOJN_03301 1.7e-221 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
KKDGPOJN_03302 1e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KKDGPOJN_03303 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KKDGPOJN_03304 5.4e-270 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KKDGPOJN_03305 0.0 lytB 3.5.1.28 D Stage II sporulation protein
KKDGPOJN_03306 8.6e-48
KKDGPOJN_03307 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KKDGPOJN_03308 4.1e-209 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KKDGPOJN_03309 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KKDGPOJN_03310 3.2e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KKDGPOJN_03311 1.7e-151 tagG GM Transport permease protein
KKDGPOJN_03312 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KKDGPOJN_03313 4.7e-293 M Glycosyltransferase like family 2
KKDGPOJN_03314 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KKDGPOJN_03315 6.5e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KKDGPOJN_03316 2.6e-219 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KKDGPOJN_03317 1.1e-241 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KKDGPOJN_03318 2e-185 pmi 5.3.1.8 G mannose-6-phosphate isomerase
KKDGPOJN_03319 1.6e-263 gerBA EG Spore germination protein
KKDGPOJN_03320 1.5e-195 gerBB E Spore germination protein
KKDGPOJN_03321 2.5e-211 gerAC S Spore germination protein
KKDGPOJN_03322 2.2e-265 GT2,GT4 J Glycosyl transferase family 2
KKDGPOJN_03323 3.7e-249 ywtG EGP Major facilitator Superfamily
KKDGPOJN_03324 7.2e-178 ywtF K Transcriptional regulator
KKDGPOJN_03325 5.5e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
KKDGPOJN_03326 2.9e-35 yttA 2.7.13.3 S Pfam Transposase IS66
KKDGPOJN_03327 4.5e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KKDGPOJN_03328 1.3e-20 ywtC
KKDGPOJN_03329 1.2e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KKDGPOJN_03330 2.3e-70 pgsC S biosynthesis protein
KKDGPOJN_03331 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
KKDGPOJN_03332 5.9e-184 gerKA EG Spore germination protein
KKDGPOJN_03333 6.7e-193 gerKB E Spore germination protein
KKDGPOJN_03334 1.3e-202 gerKC S Spore germination B3/ GerAC like, C-terminal
KKDGPOJN_03335 1.3e-179 rbsR K transcriptional
KKDGPOJN_03336 5.7e-158 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KKDGPOJN_03337 9.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KKDGPOJN_03338 4.2e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KKDGPOJN_03339 9.3e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
KKDGPOJN_03340 5.7e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KKDGPOJN_03341 5.2e-90 batE T Sh3 type 3 domain protein
KKDGPOJN_03342 1.8e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
KKDGPOJN_03343 6.7e-147 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KKDGPOJN_03344 2.4e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KKDGPOJN_03345 9e-167 alsR K LysR substrate binding domain
KKDGPOJN_03347 3.6e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KKDGPOJN_03348 4.4e-126 ywrJ
KKDGPOJN_03349 9.2e-132 cotB
KKDGPOJN_03350 4.2e-211 cotH M Spore Coat
KKDGPOJN_03351 2.2e-09
KKDGPOJN_03352 9e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KKDGPOJN_03354 2.3e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KKDGPOJN_03355 1.9e-83 ywrC K Transcriptional regulator
KKDGPOJN_03356 5.9e-103 ywrB P Chromate transporter
KKDGPOJN_03357 3.8e-88 ywrA P COG2059 Chromate transport protein ChrA
KKDGPOJN_03359 1.2e-94 ywqN S NAD(P)H-dependent
KKDGPOJN_03360 1.8e-156 K Transcriptional regulator
KKDGPOJN_03361 3.6e-126 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KKDGPOJN_03362 2.2e-48
KKDGPOJN_03364 2.6e-44
KKDGPOJN_03365 1.2e-88
KKDGPOJN_03366 7.1e-34 M COG3209 Rhs family protein
KKDGPOJN_03367 6.8e-58 T DNase/tRNase domain of colicin-like bacteriocin
KKDGPOJN_03368 2e-49
KKDGPOJN_03369 0.0 ywqJ S Pre-toxin TG
KKDGPOJN_03370 9.5e-37 ywqI S Family of unknown function (DUF5344)
KKDGPOJN_03371 1.9e-21 S Domain of unknown function (DUF5082)
KKDGPOJN_03373 1.3e-148 ywqG S Domain of unknown function (DUF1963)
KKDGPOJN_03374 2.3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KKDGPOJN_03375 1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KKDGPOJN_03376 5.7e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KKDGPOJN_03377 5.2e-112 ywqC M biosynthesis protein
KKDGPOJN_03378 1.3e-14
KKDGPOJN_03379 9.3e-308 ywqB S SWIM zinc finger
KKDGPOJN_03380 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KKDGPOJN_03381 3e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
KKDGPOJN_03382 7.5e-138 glcR K DeoR C terminal sensor domain
KKDGPOJN_03383 3.7e-57 ssbB L Single-stranded DNA-binding protein
KKDGPOJN_03384 4e-62 ywpG
KKDGPOJN_03385 1.1e-68 ywpF S YwpF-like protein
KKDGPOJN_03386 4.1e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KKDGPOJN_03387 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KKDGPOJN_03388 1.4e-198 S aspartate phosphatase
KKDGPOJN_03389 1.1e-142 flhP N flagellar basal body
KKDGPOJN_03390 3.2e-128 flhO N flagellar basal body
KKDGPOJN_03391 2.7e-180 mbl D Rod shape-determining protein
KKDGPOJN_03392 1.8e-44 spoIIID K Stage III sporulation protein D
KKDGPOJN_03393 8.5e-72 ywoH K transcriptional
KKDGPOJN_03394 4.9e-213 ywoG EGP Major facilitator Superfamily
KKDGPOJN_03395 1.6e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
KKDGPOJN_03396 6.1e-244 ywoD EGP Major facilitator superfamily
KKDGPOJN_03397 1.3e-102 phzA Q Isochorismatase family
KKDGPOJN_03398 2.5e-228 amt P Ammonium transporter
KKDGPOJN_03399 1.7e-57 nrgB K Belongs to the P(II) protein family
KKDGPOJN_03400 3.2e-209 ftsW D Belongs to the SEDS family
KKDGPOJN_03401 4.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KKDGPOJN_03402 3.6e-70 ywnJ S VanZ like family
KKDGPOJN_03403 8.4e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KKDGPOJN_03404 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KKDGPOJN_03405 1.2e-10 ywnC S Family of unknown function (DUF5362)
KKDGPOJN_03406 2.7e-68 ywnF S Family of unknown function (DUF5392)
KKDGPOJN_03407 2.4e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KKDGPOJN_03408 3.1e-52 ywnC S Family of unknown function (DUF5362)
KKDGPOJN_03409 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
KKDGPOJN_03410 1.8e-66 ywnA K Transcriptional regulator
KKDGPOJN_03411 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KKDGPOJN_03412 7.2e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KKDGPOJN_03413 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KKDGPOJN_03415 2.1e-82 ywmF S Peptidase M50
KKDGPOJN_03416 1.5e-94 S response regulator aspartate phosphatase
KKDGPOJN_03417 4.1e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KKDGPOJN_03418 9.3e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KKDGPOJN_03420 1.9e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
KKDGPOJN_03421 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
KKDGPOJN_03422 7.3e-189 spoIID D Stage II sporulation protein D
KKDGPOJN_03423 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KKDGPOJN_03424 2.4e-133 ywmB S TATA-box binding
KKDGPOJN_03425 1.3e-32 ywzB S membrane
KKDGPOJN_03426 3.5e-90 ywmA
KKDGPOJN_03427 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KKDGPOJN_03428 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KKDGPOJN_03429 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KKDGPOJN_03430 4.1e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KKDGPOJN_03431 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KKDGPOJN_03432 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KKDGPOJN_03433 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KKDGPOJN_03434 9.3e-130 atpB C it plays a direct role in the translocation of protons across the membrane
KKDGPOJN_03435 2.1e-61 atpI S ATP synthase
KKDGPOJN_03436 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KKDGPOJN_03437 7.3e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KKDGPOJN_03438 5.9e-97 ywlG S Belongs to the UPF0340 family
KKDGPOJN_03439 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KKDGPOJN_03440 9.6e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KKDGPOJN_03441 4.5e-84 mntP P Probably functions as a manganese efflux pump
KKDGPOJN_03442 2.1e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KKDGPOJN_03443 1.8e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
KKDGPOJN_03444 4.4e-110 spoIIR S stage II sporulation protein R
KKDGPOJN_03445 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
KKDGPOJN_03447 1.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KKDGPOJN_03448 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KKDGPOJN_03449 5.8e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KKDGPOJN_03450 1.3e-94 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KKDGPOJN_03451 3.6e-158 ywkB S Membrane transport protein
KKDGPOJN_03452 0.0 sfcA 1.1.1.38 C malic enzyme
KKDGPOJN_03453 4.6e-103 tdk 2.7.1.21 F thymidine kinase
KKDGPOJN_03454 1.1e-32 rpmE J Binds the 23S rRNA
KKDGPOJN_03455 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KKDGPOJN_03456 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KKDGPOJN_03457 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KKDGPOJN_03458 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KKDGPOJN_03459 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KKDGPOJN_03460 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
KKDGPOJN_03461 1.7e-93 ywjG S Domain of unknown function (DUF2529)
KKDGPOJN_03462 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KKDGPOJN_03463 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KKDGPOJN_03464 0.0 fadF C COG0247 Fe-S oxidoreductase
KKDGPOJN_03465 1e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KKDGPOJN_03466 5.2e-181 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KKDGPOJN_03467 4.2e-43 ywjC
KKDGPOJN_03468 0.0 ywjA V ABC transporter
KKDGPOJN_03469 1.3e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KKDGPOJN_03470 4.9e-103 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KKDGPOJN_03471 1.5e-123 narI 1.7.5.1 C nitrate reductase, gamma
KKDGPOJN_03472 5.6e-95 narJ 1.7.5.1 C nitrate reductase
KKDGPOJN_03473 4.8e-295 narH 1.7.5.1 C Nitrate reductase, beta
KKDGPOJN_03474 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KKDGPOJN_03475 3.8e-84 arfM T cyclic nucleotide binding
KKDGPOJN_03476 1.8e-138 ywiC S YwiC-like protein
KKDGPOJN_03477 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
KKDGPOJN_03478 9.8e-214 narK P COG2223 Nitrate nitrite transporter
KKDGPOJN_03479 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KKDGPOJN_03480 1.1e-42 ywiB S protein conserved in bacteria
KKDGPOJN_03481 1.4e-76 S aspartate phosphatase
KKDGPOJN_03483 9.7e-29 ydcG K sequence-specific DNA binding
KKDGPOJN_03484 5e-33
KKDGPOJN_03485 2e-28 S Domain of unknown function (DUF4177)
KKDGPOJN_03487 8.1e-77 CP Membrane
KKDGPOJN_03490 2.1e-168 speB 3.5.3.11 E Belongs to the arginase family
KKDGPOJN_03491 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KKDGPOJN_03492 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KKDGPOJN_03493 2.1e-81
KKDGPOJN_03494 1.4e-95 ywhD S YwhD family
KKDGPOJN_03495 1.2e-117 ywhC S Peptidase family M50
KKDGPOJN_03496 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KKDGPOJN_03497 8e-70 ywhA K Transcriptional regulator
KKDGPOJN_03498 1.5e-246 yhdG_1 E C-terminus of AA_permease
KKDGPOJN_03499 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
KKDGPOJN_03500 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
KKDGPOJN_03501 6.9e-36 ywzC S Belongs to the UPF0741 family
KKDGPOJN_03502 3e-110 rsfA_1
KKDGPOJN_03503 5.3e-50 padR K PadR family transcriptional regulator
KKDGPOJN_03504 4.4e-92 S membrane
KKDGPOJN_03505 1.9e-164 V ABC transporter, ATP-binding protein
KKDGPOJN_03506 2.9e-168 yhcI S ABC transporter (permease)
KKDGPOJN_03509 2.9e-184
KKDGPOJN_03511 6.1e-157 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KKDGPOJN_03512 3e-162 cysL K Transcriptional regulator
KKDGPOJN_03513 4e-157 MA20_14895 S Conserved hypothetical protein 698
KKDGPOJN_03514 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KKDGPOJN_03515 1.1e-146 ywfI C May function as heme-dependent peroxidase
KKDGPOJN_03516 3.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
KKDGPOJN_03517 3.5e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
KKDGPOJN_03518 1.8e-207 bacE EGP Major facilitator Superfamily
KKDGPOJN_03519 2.2e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KKDGPOJN_03520 3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KKDGPOJN_03521 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KKDGPOJN_03522 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KKDGPOJN_03523 7.1e-223 ywfA EGP Major facilitator Superfamily
KKDGPOJN_03524 5.3e-207 tcaB EGP Major facilitator Superfamily
KKDGPOJN_03525 7.5e-261 lysP E amino acid
KKDGPOJN_03526 0.0 rocB E arginine degradation protein
KKDGPOJN_03527 5.1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KKDGPOJN_03528 5.6e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KKDGPOJN_03529 3.5e-158 T PhoQ Sensor
KKDGPOJN_03530 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKDGPOJN_03531 1.3e-74
KKDGPOJN_03532 2.3e-117 S ABC-2 family transporter protein
KKDGPOJN_03533 1.3e-171 bcrA5 V ABC transporter, ATP-binding protein
KKDGPOJN_03534 3.5e-87 spsL 5.1.3.13 M Spore Coat
KKDGPOJN_03535 1.1e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KKDGPOJN_03536 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KKDGPOJN_03537 1.6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KKDGPOJN_03538 1.7e-182 spsG M Spore Coat
KKDGPOJN_03539 8.2e-134 spsF M Spore Coat
KKDGPOJN_03540 1.3e-212 spsE 2.5.1.56 M acid synthase
KKDGPOJN_03541 3.6e-157 spsD 2.3.1.210 K Spore Coat
KKDGPOJN_03542 1.8e-220 spsC E Belongs to the DegT DnrJ EryC1 family
KKDGPOJN_03543 5.4e-275 spsB M Capsule polysaccharide biosynthesis protein
KKDGPOJN_03544 2.6e-143 spsA M Spore Coat
KKDGPOJN_03545 2.3e-54 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KKDGPOJN_03546 4.2e-46 ywdK S small membrane protein
KKDGPOJN_03547 3.2e-229 ywdJ F Xanthine uracil
KKDGPOJN_03548 7.3e-41 ywdI S Family of unknown function (DUF5327)
KKDGPOJN_03549 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KKDGPOJN_03550 1.2e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
KKDGPOJN_03552 9.9e-88 ywdD
KKDGPOJN_03553 6.3e-57 pex K Transcriptional regulator PadR-like family
KKDGPOJN_03554 6.6e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KKDGPOJN_03555 9.7e-20 ywdA
KKDGPOJN_03556 1e-281 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
KKDGPOJN_03557 2.4e-248 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KKDGPOJN_03558 1.4e-150 sacT K transcriptional antiterminator
KKDGPOJN_03560 0.0 vpr O Belongs to the peptidase S8 family
KKDGPOJN_03561 1.8e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KKDGPOJN_03562 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KKDGPOJN_03563 1.2e-211 rodA D Belongs to the SEDS family
KKDGPOJN_03564 1.8e-79 ysnE K acetyltransferase
KKDGPOJN_03565 3e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
KKDGPOJN_03566 9.9e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KKDGPOJN_03567 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KKDGPOJN_03568 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KKDGPOJN_03569 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KKDGPOJN_03570 4.2e-26 ywzA S membrane
KKDGPOJN_03571 3.3e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KKDGPOJN_03572 5e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KKDGPOJN_03573 2.3e-61 gtcA S GtrA-like protein
KKDGPOJN_03574 4.3e-112 ywcC K Bacterial regulatory proteins, tetR family
KKDGPOJN_03576 8e-128 H Methionine biosynthesis protein MetW
KKDGPOJN_03577 1.2e-131 S Streptomycin biosynthesis protein StrF
KKDGPOJN_03578 2.7e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KKDGPOJN_03579 1.6e-238 ywbN P Dyp-type peroxidase family protein
KKDGPOJN_03580 1.2e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KKDGPOJN_03581 2.4e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KKDGPOJN_03582 8.2e-152 ywbI K Transcriptional regulator
KKDGPOJN_03583 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KKDGPOJN_03584 3.4e-110 ywbG M effector of murein hydrolase
KKDGPOJN_03585 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
KKDGPOJN_03586 9.3e-141 mta K transcriptional
KKDGPOJN_03587 1.5e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
KKDGPOJN_03588 8e-224 ywbD 2.1.1.191 J Methyltransferase
KKDGPOJN_03589 4.9e-66 ywbC 4.4.1.5 E glyoxalase
KKDGPOJN_03590 7.1e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKDGPOJN_03591 1.1e-264 epr 3.4.21.62 O Belongs to the peptidase S8 family
KKDGPOJN_03592 4.4e-163 gspA M General stress
KKDGPOJN_03593 6.7e-47 ywaE K Transcriptional regulator
KKDGPOJN_03594 1.1e-196 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KKDGPOJN_03595 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
KKDGPOJN_03596 1.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KKDGPOJN_03597 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
KKDGPOJN_03598 2.3e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKDGPOJN_03599 3.7e-229 dltB M membrane protein involved in D-alanine export
KKDGPOJN_03600 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKDGPOJN_03601 1.8e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KKDGPOJN_03602 2.2e-204 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KKDGPOJN_03603 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KKDGPOJN_03604 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KKDGPOJN_03605 2.8e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKDGPOJN_03606 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
KKDGPOJN_03607 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
KKDGPOJN_03608 3.6e-108 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KKDGPOJN_03609 4.3e-173 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKDGPOJN_03610 1.3e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KKDGPOJN_03611 3.7e-165 cbrA3 P Periplasmic binding protein
KKDGPOJN_03612 1.6e-58 arsR K transcriptional
KKDGPOJN_03613 4.5e-228 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KKDGPOJN_03614 9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
KKDGPOJN_03615 1.7e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
KKDGPOJN_03616 1.8e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKDGPOJN_03617 1.7e-286 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKDGPOJN_03618 6.2e-165 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KKDGPOJN_03619 9.9e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
KKDGPOJN_03620 1.6e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KKDGPOJN_03621 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KKDGPOJN_03622 5.5e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KKDGPOJN_03623 3.6e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
KKDGPOJN_03624 6.1e-154 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KKDGPOJN_03625 1.3e-291 cydD V ATP-binding protein
KKDGPOJN_03626 0.0 cydD V ATP-binding
KKDGPOJN_03627 5.5e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KKDGPOJN_03628 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
KKDGPOJN_03629 5.9e-215 cimH C COG3493 Na citrate symporter
KKDGPOJN_03630 1.3e-156 yxkH G Polysaccharide deacetylase
KKDGPOJN_03631 2.6e-205 msmK P Belongs to the ABC transporter superfamily
KKDGPOJN_03632 5.4e-164 lrp QT PucR C-terminal helix-turn-helix domain
KKDGPOJN_03633 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KKDGPOJN_03634 3.8e-87 yxkC S Domain of unknown function (DUF4352)
KKDGPOJN_03635 3.9e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KKDGPOJN_03636 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KKDGPOJN_03639 9.1e-86 yxjI S LURP-one-related
KKDGPOJN_03640 2.8e-218 yxjG 2.1.1.14 E Methionine synthase
KKDGPOJN_03641 1.5e-155 rlmA 2.1.1.187 Q Methyltransferase domain
KKDGPOJN_03642 1.1e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KKDGPOJN_03643 2.7e-75 T Domain of unknown function (DUF4163)
KKDGPOJN_03644 8.2e-45 yxiS
KKDGPOJN_03645 3e-124 L DNA synthesis involved in DNA repair
KKDGPOJN_03646 1.8e-37 L DNA synthesis involved in DNA repair
KKDGPOJN_03647 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
KKDGPOJN_03648 4e-221 citH C Citrate transporter
KKDGPOJN_03649 2.3e-141 exoK GH16 M licheninase activity
KKDGPOJN_03650 1.7e-146 licT K transcriptional antiterminator
KKDGPOJN_03651 1.3e-221 yxiO S COG2270 Permeases of the major facilitator superfamily
KKDGPOJN_03652 1.2e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KKDGPOJN_03654 3.1e-17
KKDGPOJN_03657 6.6e-69 yxiG
KKDGPOJN_03658 2.1e-62 yxxG
KKDGPOJN_03660 0.0 wapA M COG3209 Rhs family protein
KKDGPOJN_03661 2.9e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
KKDGPOJN_03662 1.2e-147 yxxF EG EamA-like transporter family
KKDGPOJN_03663 4.1e-72 yxiE T Belongs to the universal stress protein A family
KKDGPOJN_03664 0.0 L HKD family nuclease
KKDGPOJN_03665 1.1e-60 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KKDGPOJN_03666 5.7e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KKDGPOJN_03667 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KKDGPOJN_03668 2.1e-285 hutH 4.3.1.3 E Histidine ammonia-lyase
KKDGPOJN_03669 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KKDGPOJN_03670 1.1e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
KKDGPOJN_03671 1.7e-176 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KKDGPOJN_03672 9.8e-253 lysP E amino acid
KKDGPOJN_03673 3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KKDGPOJN_03674 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KKDGPOJN_03675 3.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KKDGPOJN_03676 1.6e-171 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KKDGPOJN_03677 7.6e-149 yidA S hydrolases of the HAD superfamily
KKDGPOJN_03680 5.2e-07 yxeE
KKDGPOJN_03681 8.4e-23 yxeD
KKDGPOJN_03682 6e-35
KKDGPOJN_03683 5.4e-178 fhuD P Periplasmic binding protein
KKDGPOJN_03684 1.3e-57 yxeA S Protein of unknown function (DUF1093)
KKDGPOJN_03685 0.0 yxdM V ABC transporter (permease)
KKDGPOJN_03686 5.5e-141 yxdL V ABC transporter, ATP-binding protein
KKDGPOJN_03687 2.3e-176 T PhoQ Sensor
KKDGPOJN_03688 1e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKDGPOJN_03689 2.7e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KKDGPOJN_03690 1.7e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KKDGPOJN_03691 1.1e-166 iolH G Xylose isomerase-like TIM barrel
KKDGPOJN_03692 4.7e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KKDGPOJN_03693 1.5e-231 iolF EGP Major facilitator Superfamily
KKDGPOJN_03694 1.5e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KKDGPOJN_03695 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KKDGPOJN_03696 4.4e-183 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KKDGPOJN_03697 6.4e-156 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KKDGPOJN_03698 2.1e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KKDGPOJN_03699 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
KKDGPOJN_03700 1.4e-175 iolS C Aldo keto reductase
KKDGPOJN_03701 6.7e-246 csbC EGP Major facilitator Superfamily
KKDGPOJN_03702 0.0 htpG O Molecular chaperone. Has ATPase activity
KKDGPOJN_03704 2.1e-151 IQ Enoyl-(Acyl carrier protein) reductase
KKDGPOJN_03705 3.9e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KKDGPOJN_03706 1.9e-198 desK 2.7.13.3 T Histidine kinase
KKDGPOJN_03707 1.9e-200 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KKDGPOJN_03708 4.1e-217 yxbF K Bacterial regulatory proteins, tetR family
KKDGPOJN_03709 2.5e-250 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KKDGPOJN_03710 1.1e-141 S PQQ-like domain
KKDGPOJN_03711 1.9e-63 S Family of unknown function (DUF5391)
KKDGPOJN_03712 1.7e-50 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
KKDGPOJN_03713 2.9e-202 EGP Major facilitator Superfamily
KKDGPOJN_03714 7.6e-74 yxaI S membrane protein domain
KKDGPOJN_03715 3.2e-124 E Ring-cleavage extradiol dioxygenase
KKDGPOJN_03716 1.3e-21 3.4.24.84 O metalloendopeptidase activity
KKDGPOJN_03717 1.6e-91 mrr V Mrr N-terminal domain
KKDGPOJN_03718 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KKDGPOJN_03719 5e-287 ahpF O Alkyl hydroperoxide reductase
KKDGPOJN_03720 3.6e-227 XK27_00240 S Fic/DOC family
KKDGPOJN_03721 3.2e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
KKDGPOJN_03722 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
KKDGPOJN_03723 1.1e-83 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KKDGPOJN_03724 1.9e-155 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KKDGPOJN_03725 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KKDGPOJN_03726 2.6e-88 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KKDGPOJN_03727 2.2e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KKDGPOJN_03728 5.1e-179 S Fusaric acid resistance protein-like
KKDGPOJN_03729 1.5e-18
KKDGPOJN_03730 2.2e-77 K SIR2-like domain
KKDGPOJN_03731 4.1e-96 D AAA domain
KKDGPOJN_03732 4.8e-93
KKDGPOJN_03733 2.6e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KKDGPOJN_03734 7.9e-08 S YyzF-like protein
KKDGPOJN_03736 1.7e-218 yycP
KKDGPOJN_03737 8.3e-134 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KKDGPOJN_03738 5.1e-184 C oxidoreductases (related to aryl-alcohol dehydrogenases)
KKDGPOJN_03739 3.7e-87 yycN 2.3.1.128 K Acetyltransferase
KKDGPOJN_03741 1.7e-199 S Histidine kinase
KKDGPOJN_03742 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KKDGPOJN_03743 5e-257 rocE E amino acid
KKDGPOJN_03744 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KKDGPOJN_03745 7.7e-64 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
KKDGPOJN_03746 2.2e-42 sdpR K transcriptional
KKDGPOJN_03747 1.2e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KKDGPOJN_03748 2e-145 1.14.11.27 P peptidyl-arginine hydroxylation
KKDGPOJN_03749 8.8e-306 S ABC transporter
KKDGPOJN_03750 4.4e-198 S Major Facilitator Superfamily
KKDGPOJN_03751 3.8e-259
KKDGPOJN_03752 1.3e-190 2.7.7.73, 2.7.7.80 H ThiF family
KKDGPOJN_03753 1.2e-250 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
KKDGPOJN_03754 2.2e-93 K PFAM response regulator receiver
KKDGPOJN_03755 2.1e-62 S Peptidase propeptide and YPEB domain
KKDGPOJN_03756 6e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KKDGPOJN_03757 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KKDGPOJN_03758 1.9e-150 yycI S protein conserved in bacteria
KKDGPOJN_03759 2.7e-260 yycH S protein conserved in bacteria
KKDGPOJN_03760 0.0 vicK 2.7.13.3 T Histidine kinase
KKDGPOJN_03761 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KKDGPOJN_03766 2.5e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KKDGPOJN_03767 4.7e-70 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KKDGPOJN_03768 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KKDGPOJN_03769 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
KKDGPOJN_03771 4.6e-17 yycC K YycC-like protein
KKDGPOJN_03772 1e-258 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KKDGPOJN_03773 3e-240 M Glycosyltransferase Family 4
KKDGPOJN_03774 2.2e-204 S Ecdysteroid kinase
KKDGPOJN_03775 3.5e-235 S Carbamoyl-phosphate synthase L chain, ATP binding domain
KKDGPOJN_03776 1.3e-235 M Glycosyltransferase Family 4
KKDGPOJN_03777 2.7e-120 S GlcNAc-PI de-N-acetylase
KKDGPOJN_03778 1.8e-88 KLT COG0515 Serine threonine protein kinase
KKDGPOJN_03779 4.9e-73 rplI J binds to the 23S rRNA
KKDGPOJN_03780 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KKDGPOJN_03781 3.5e-158 yybS S membrane
KKDGPOJN_03783 6.5e-85 cotF M Spore coat protein
KKDGPOJN_03784 2.8e-66 ydeP3 K Transcriptional regulator
KKDGPOJN_03785 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KKDGPOJN_03786 5.7e-155 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KKDGPOJN_03787 6.5e-273 sacB 2.4.1.10 GH68 M levansucrase activity
KKDGPOJN_03788 2.7e-310 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
KKDGPOJN_03789 3.4e-115 K FCD domain
KKDGPOJN_03790 5.4e-76 dinB S PFAM DinB family protein
KKDGPOJN_03791 2.6e-161 G Major Facilitator Superfamily
KKDGPOJN_03793 1.1e-54 ypaA S Protein of unknown function (DUF1304)
KKDGPOJN_03794 9.6e-115 drgA C nitroreductase
KKDGPOJN_03795 4.1e-69 ydgJ K Winged helix DNA-binding domain
KKDGPOJN_03796 1.4e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KKDGPOJN_03797 5.6e-77 yybA 2.3.1.57 K transcriptional
KKDGPOJN_03798 3.5e-76 yjcF S Acetyltransferase (GNAT) domain
KKDGPOJN_03799 2.6e-163 eaeH M Domain of Unknown Function (DUF1259)
KKDGPOJN_03800 4.2e-41 3.1.3.18 S glycolate biosynthetic process
KKDGPOJN_03801 4.9e-46 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
KKDGPOJN_03802 4.5e-97
KKDGPOJN_03803 3.5e-66 S Leucine-rich repeat (LRR) protein
KKDGPOJN_03804 4.2e-19
KKDGPOJN_03805 1.6e-68 isp O Belongs to the peptidase S8 family
KKDGPOJN_03806 9.4e-251 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KKDGPOJN_03807 3.8e-130 ydfC EG EamA-like transporter family
KKDGPOJN_03808 1.1e-122 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KKDGPOJN_03810 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KKDGPOJN_03811 3.5e-163 yyaK S CAAX protease self-immunity
KKDGPOJN_03812 3.4e-247 ydjK G Sugar (and other) transporter
KKDGPOJN_03813 6e-64 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KKDGPOJN_03814 5.2e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
KKDGPOJN_03815 5.7e-39 xth 3.1.11.2 L exodeoxyribonuclease III
KKDGPOJN_03816 2.4e-98 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KKDGPOJN_03817 8.7e-107 adaA 3.2.2.21 K Transcriptional regulator
KKDGPOJN_03818 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KKDGPOJN_03819 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KKDGPOJN_03820 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
KKDGPOJN_03821 3.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KKDGPOJN_03822 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KKDGPOJN_03823 2.3e-33 yyzM S protein conserved in bacteria
KKDGPOJN_03824 1.5e-175 yyaD S Membrane
KKDGPOJN_03825 6.2e-111 yyaC S Sporulation protein YyaC
KKDGPOJN_03826 3e-148 spo0J K Belongs to the ParB family
KKDGPOJN_03827 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
KKDGPOJN_03828 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KKDGPOJN_03829 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KKDGPOJN_03830 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KKDGPOJN_03831 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KKDGPOJN_03832 3.5e-109 jag S single-stranded nucleic acid binding R3H
KKDGPOJN_03833 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KKDGPOJN_03834 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)