ORF_ID e_value Gene_name EC_number CAZy COGs Description
NLLAEHGB_00001 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_00002 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_00003 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_00004 1.7e-298 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NLLAEHGB_00005 4.8e-251 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
NLLAEHGB_00006 2.2e-128 T Transcriptional regulatory protein, C terminal
NLLAEHGB_00007 6.9e-235 T PhoQ Sensor
NLLAEHGB_00008 2.8e-51 S Domain of unknown function (DUF4870)
NLLAEHGB_00009 8.7e-292 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NLLAEHGB_00010 1.2e-216 S Platelet-activating factor acetylhydrolase, isoform II
NLLAEHGB_00011 1.4e-14
NLLAEHGB_00013 5.7e-64 V ABC transporter
NLLAEHGB_00014 1.6e-84 S Protein of unknown function (DUF1430)
NLLAEHGB_00015 9.7e-305 yndJ S YndJ-like protein
NLLAEHGB_00016 4e-78 yndH S Domain of unknown function (DUF4166)
NLLAEHGB_00017 3.4e-157 yndG S DoxX-like family
NLLAEHGB_00018 2.9e-224 exuT G Sugar (and other) transporter
NLLAEHGB_00019 5.4e-181 kdgR_1 K transcriptional
NLLAEHGB_00020 2e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NLLAEHGB_00021 1.6e-207 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NLLAEHGB_00022 8.9e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NLLAEHGB_00023 6.9e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NLLAEHGB_00024 1e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NLLAEHGB_00025 4.6e-250 agcS E Sodium alanine symporter
NLLAEHGB_00026 5.1e-41 ynfC
NLLAEHGB_00027 6e-13
NLLAEHGB_00028 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLLAEHGB_00029 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLLAEHGB_00030 1.5e-68 yccU S CoA-binding protein
NLLAEHGB_00031 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NLLAEHGB_00032 1.3e-50 yneR S Belongs to the HesB IscA family
NLLAEHGB_00033 4.4e-54 yneQ
NLLAEHGB_00034 8.3e-75 yneP S Thioesterase-like superfamily
NLLAEHGB_00035 2.7e-33 tlp S Belongs to the Tlp family
NLLAEHGB_00037 1.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NLLAEHGB_00038 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NLLAEHGB_00039 7.5e-15 sspO S Belongs to the SspO family
NLLAEHGB_00040 2.3e-19 sspP S Belongs to the SspP family
NLLAEHGB_00041 3.2e-62 hspX O Spore coat protein
NLLAEHGB_00042 8.5e-75 yneK S Protein of unknown function (DUF2621)
NLLAEHGB_00043 3.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NLLAEHGB_00044 1.4e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NLLAEHGB_00045 1.7e-125 ccdA O cytochrome c biogenesis protein
NLLAEHGB_00046 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
NLLAEHGB_00047 2.3e-28 yneF S UPF0154 protein
NLLAEHGB_00048 2.8e-81 yneE S Sporulation inhibitor of replication protein sirA
NLLAEHGB_00049 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NLLAEHGB_00050 9.8e-33 ynzC S UPF0291 protein
NLLAEHGB_00051 3.5e-112 yneB L resolvase
NLLAEHGB_00052 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NLLAEHGB_00053 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NLLAEHGB_00054 9.2e-13 yoaW
NLLAEHGB_00055 5.4e-72 yndM S Protein of unknown function (DUF2512)
NLLAEHGB_00056 1.2e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
NLLAEHGB_00057 1.6e-07
NLLAEHGB_00058 2.3e-145 yndL S Replication protein
NLLAEHGB_00059 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NLLAEHGB_00060 0.0 yobO M Pectate lyase superfamily protein
NLLAEHGB_00062 3.9e-14 yvgO
NLLAEHGB_00063 6.5e-43 yvgO
NLLAEHGB_00065 1.3e-116 AA10,CBM73 S Pfam:Chitin_bind_3
NLLAEHGB_00066 5.4e-203 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLLAEHGB_00068 8.6e-98 ynaE S Domain of unknown function (DUF3885)
NLLAEHGB_00071 4.8e-37
NLLAEHGB_00072 1.8e-98 J Acetyltransferase (GNAT) domain
NLLAEHGB_00073 3.6e-145 yoaP 3.1.3.18 K YoaP-like
NLLAEHGB_00075 1.4e-43
NLLAEHGB_00078 3.6e-09 ccmM S Bacterial transferase hexapeptide (six repeats)
NLLAEHGB_00079 1.9e-186 adhP 1.1.1.1 C alcohol dehydrogenase
NLLAEHGB_00080 5.4e-17
NLLAEHGB_00083 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NLLAEHGB_00084 5.8e-288 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
NLLAEHGB_00085 1.7e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NLLAEHGB_00086 2.7e-216 xylR GK ROK family
NLLAEHGB_00087 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NLLAEHGB_00088 4.3e-253 xynT G MFS/sugar transport protein
NLLAEHGB_00089 6.9e-214 mrjp G Major royal jelly protein
NLLAEHGB_00092 2.6e-48 S aspartate phosphatase
NLLAEHGB_00093 6.2e-17 S aspartate phosphatase
NLLAEHGB_00094 3.4e-33 yobL L nucleic acid phosphodiester bond hydrolysis
NLLAEHGB_00095 1.7e-09 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NLLAEHGB_00096 9.4e-77 A Pre-toxin TG
NLLAEHGB_00097 4.4e-37 S High confidence in function and specificity
NLLAEHGB_00098 2.6e-24
NLLAEHGB_00100 5.2e-25 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NLLAEHGB_00101 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
NLLAEHGB_00102 4.3e-68 glnR K transcriptional
NLLAEHGB_00103 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NLLAEHGB_00104 8.5e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NLLAEHGB_00105 1.3e-176 spoVK O stage V sporulation protein K
NLLAEHGB_00106 1.9e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NLLAEHGB_00107 2.4e-110 ymaB S MutT family
NLLAEHGB_00108 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLLAEHGB_00109 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLLAEHGB_00110 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NLLAEHGB_00111 1.8e-20 ymzA
NLLAEHGB_00112 8.5e-44
NLLAEHGB_00113 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NLLAEHGB_00114 6.7e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NLLAEHGB_00115 1.4e-47 ymaF S YmaF family
NLLAEHGB_00117 3.1e-48 ebrA P Small Multidrug Resistance protein
NLLAEHGB_00118 2.6e-53 ebrB P Small Multidrug Resistance protein
NLLAEHGB_00119 3.9e-78 ymaD O redox protein, regulator of disulfide bond formation
NLLAEHGB_00120 4.1e-127 ymaC S Replication protein
NLLAEHGB_00122 4e-256 aprX O Belongs to the peptidase S8 family
NLLAEHGB_00123 1.4e-62 ymzB
NLLAEHGB_00124 6.1e-118 yoaK S Membrane
NLLAEHGB_00125 6.4e-78 nucB M Deoxyribonuclease NucA/NucB
NLLAEHGB_00126 5.3e-231 cypA C Cytochrome P450
NLLAEHGB_00127 0.0 pks13 HQ Beta-ketoacyl synthase
NLLAEHGB_00128 0.0 dhbF IQ polyketide synthase
NLLAEHGB_00129 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
NLLAEHGB_00130 0.0 Q Polyketide synthase of type I
NLLAEHGB_00131 0.0 rhiB IQ polyketide synthase
NLLAEHGB_00132 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NLLAEHGB_00133 5.3e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
NLLAEHGB_00134 1.3e-243 pksG 2.3.3.10 I synthase
NLLAEHGB_00135 1.3e-35 acpK IQ Phosphopantetheine attachment site
NLLAEHGB_00136 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NLLAEHGB_00137 1.5e-183 pksD Q Acyl transferase domain
NLLAEHGB_00138 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NLLAEHGB_00139 2.2e-128 pksB 3.1.2.6 S Polyketide biosynthesis
NLLAEHGB_00141 4.2e-36
NLLAEHGB_00142 6.3e-13 L Belongs to the 'phage' integrase family
NLLAEHGB_00143 1.7e-47 L Belongs to the 'phage' integrase family
NLLAEHGB_00144 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NLLAEHGB_00145 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NLLAEHGB_00146 1.7e-88 cotE S Spore coat protein
NLLAEHGB_00147 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NLLAEHGB_00148 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NLLAEHGB_00149 3.9e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NLLAEHGB_00150 1.5e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NLLAEHGB_00151 1.2e-36 spoVS S Stage V sporulation protein S
NLLAEHGB_00152 4.9e-153 ymdB S protein conserved in bacteria
NLLAEHGB_00153 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
NLLAEHGB_00154 5e-194 pbpX V Beta-lactamase
NLLAEHGB_00155 2.6e-186 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NLLAEHGB_00156 3.8e-232 cinA 3.5.1.42 S Belongs to the CinA family
NLLAEHGB_00157 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NLLAEHGB_00158 1.1e-124 ymfM S protein conserved in bacteria
NLLAEHGB_00159 3.5e-143 ymfK S Protein of unknown function (DUF3388)
NLLAEHGB_00160 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
NLLAEHGB_00161 3e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NLLAEHGB_00162 3.7e-243 ymfH S zinc protease
NLLAEHGB_00163 1.2e-238 ymfF S Peptidase M16
NLLAEHGB_00164 0.0 ydgH S drug exporters of the RND superfamily
NLLAEHGB_00165 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
NLLAEHGB_00166 6.5e-227 ymfD EGP Major facilitator Superfamily
NLLAEHGB_00167 1.8e-133 ymfC K Transcriptional regulator
NLLAEHGB_00168 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NLLAEHGB_00169 6.3e-31 S YlzJ-like protein
NLLAEHGB_00170 7.6e-132 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NLLAEHGB_00171 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLLAEHGB_00172 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLLAEHGB_00173 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NLLAEHGB_00174 1.7e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NLLAEHGB_00175 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NLLAEHGB_00176 1.2e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NLLAEHGB_00177 2.6e-42 ymxH S YlmC YmxH family
NLLAEHGB_00178 6.8e-234 pepR S Belongs to the peptidase M16 family
NLLAEHGB_00179 8e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NLLAEHGB_00180 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NLLAEHGB_00181 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NLLAEHGB_00182 1.5e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NLLAEHGB_00183 5.2e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NLLAEHGB_00184 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NLLAEHGB_00185 3.9e-44 ylxP S protein conserved in bacteria
NLLAEHGB_00186 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NLLAEHGB_00187 1.8e-47 ylxQ J ribosomal protein
NLLAEHGB_00188 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
NLLAEHGB_00189 2.7e-205 nusA K Participates in both transcription termination and antitermination
NLLAEHGB_00190 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
NLLAEHGB_00191 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLLAEHGB_00192 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NLLAEHGB_00193 3.4e-233 rasP M zinc metalloprotease
NLLAEHGB_00194 1.9e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NLLAEHGB_00195 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
NLLAEHGB_00196 2.9e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NLLAEHGB_00197 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NLLAEHGB_00198 4.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NLLAEHGB_00199 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NLLAEHGB_00200 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NLLAEHGB_00201 8.1e-55 ylxL
NLLAEHGB_00202 1.1e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NLLAEHGB_00203 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NLLAEHGB_00204 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NLLAEHGB_00205 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
NLLAEHGB_00206 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NLLAEHGB_00207 2.5e-192 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NLLAEHGB_00208 1.2e-155 flhG D Belongs to the ParA family
NLLAEHGB_00209 1.1e-192 flhF N Flagellar biosynthesis regulator FlhF
NLLAEHGB_00210 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NLLAEHGB_00211 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NLLAEHGB_00212 5.2e-131 fliR N Flagellar biosynthetic protein FliR
NLLAEHGB_00213 2e-37 fliQ N Role in flagellar biosynthesis
NLLAEHGB_00214 5.7e-110 fliP N Plays a role in the flagellum-specific transport system
NLLAEHGB_00215 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
NLLAEHGB_00216 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NLLAEHGB_00217 1.8e-185 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NLLAEHGB_00218 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NLLAEHGB_00219 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
NLLAEHGB_00220 4e-139 flgG N Flagellar basal body rod
NLLAEHGB_00221 1.4e-72 flgD N Flagellar basal body rod modification protein
NLLAEHGB_00222 8.8e-203 fliK N Flagellar hook-length control protein
NLLAEHGB_00223 4.4e-48 ylxF S MgtE intracellular N domain
NLLAEHGB_00224 4.5e-71 fliJ N Flagellar biosynthesis chaperone
NLLAEHGB_00225 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NLLAEHGB_00226 3.7e-89 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NLLAEHGB_00227 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NLLAEHGB_00228 4.1e-263 fliF N The M ring may be actively involved in energy transduction
NLLAEHGB_00229 2.5e-31 fliE N Flagellar hook-basal body
NLLAEHGB_00230 2.4e-75 flgC N Belongs to the flagella basal body rod proteins family
NLLAEHGB_00231 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NLLAEHGB_00232 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NLLAEHGB_00233 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NLLAEHGB_00234 2e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NLLAEHGB_00235 6.1e-171 xerC L tyrosine recombinase XerC
NLLAEHGB_00236 4.8e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NLLAEHGB_00237 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NLLAEHGB_00238 3e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NLLAEHGB_00239 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NLLAEHGB_00240 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NLLAEHGB_00241 6.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NLLAEHGB_00242 4.9e-307 ylqG
NLLAEHGB_00243 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLLAEHGB_00244 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NLLAEHGB_00245 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NLLAEHGB_00246 5.4e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NLLAEHGB_00247 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NLLAEHGB_00248 1.3e-61 ylqD S YlqD protein
NLLAEHGB_00249 1.7e-35 ylqC S Belongs to the UPF0109 family
NLLAEHGB_00250 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NLLAEHGB_00251 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NLLAEHGB_00252 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NLLAEHGB_00253 2.1e-140 S Phosphotransferase enzyme family
NLLAEHGB_00254 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NLLAEHGB_00255 0.0 smc D Required for chromosome condensation and partitioning
NLLAEHGB_00256 4.4e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NLLAEHGB_00257 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLLAEHGB_00258 4.6e-129 IQ reductase
NLLAEHGB_00259 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NLLAEHGB_00260 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NLLAEHGB_00261 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NLLAEHGB_00262 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NLLAEHGB_00263 7.1e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NLLAEHGB_00264 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
NLLAEHGB_00265 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
NLLAEHGB_00266 5.5e-59 asp S protein conserved in bacteria
NLLAEHGB_00267 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NLLAEHGB_00268 1.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
NLLAEHGB_00269 2.3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NLLAEHGB_00270 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NLLAEHGB_00271 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NLLAEHGB_00272 1.7e-139 stp 3.1.3.16 T phosphatase
NLLAEHGB_00273 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NLLAEHGB_00274 1.7e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NLLAEHGB_00275 4.3e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NLLAEHGB_00276 1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NLLAEHGB_00277 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NLLAEHGB_00278 9.7e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NLLAEHGB_00279 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NLLAEHGB_00280 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NLLAEHGB_00281 1.5e-40 ylzA S Belongs to the UPF0296 family
NLLAEHGB_00282 7.7e-155 yloC S stress-induced protein
NLLAEHGB_00283 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NLLAEHGB_00284 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NLLAEHGB_00285 2.4e-40 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_00286 9.8e-79 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_00287 6.3e-63 hxlR K transcriptional
NLLAEHGB_00288 2.5e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NLLAEHGB_00289 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NLLAEHGB_00290 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
NLLAEHGB_00291 1.4e-68 nin S Competence protein J (ComJ)
NLLAEHGB_00292 1.1e-296 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLLAEHGB_00293 2.2e-51 S Protein of unknown function (DUF2680)
NLLAEHGB_00294 1.6e-73 yckC S membrane
NLLAEHGB_00295 3.9e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NLLAEHGB_00296 6.4e-229 yciC S GTPases (G3E family)
NLLAEHGB_00297 2.4e-223 nasA P COG2223 Nitrate nitrite transporter
NLLAEHGB_00298 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NLLAEHGB_00299 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NLLAEHGB_00300 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NLLAEHGB_00301 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
NLLAEHGB_00302 1.1e-280 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NLLAEHGB_00303 2.9e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NLLAEHGB_00304 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NLLAEHGB_00305 5.8e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLLAEHGB_00306 5.2e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NLLAEHGB_00307 2.3e-170 ycgM E Proline dehydrogenase
NLLAEHGB_00308 1.5e-146 ycgL S Predicted nucleotidyltransferase
NLLAEHGB_00309 4.5e-185 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NLLAEHGB_00310 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NLLAEHGB_00311 1.4e-232 G COG0477 Permeases of the major facilitator superfamily
NLLAEHGB_00312 5.6e-149 4.2.1.118 G Xylose isomerase-like TIM barrel
NLLAEHGB_00313 3.1e-16 tmrB S AAA domain
NLLAEHGB_00314 2.4e-84 tmrB S AAA domain
NLLAEHGB_00316 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NLLAEHGB_00317 7.6e-114 ycgI S Domain of unknown function (DUF1989)
NLLAEHGB_00318 9.8e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NLLAEHGB_00319 4.9e-150 yqcI S YqcI/YcgG family
NLLAEHGB_00320 3e-113 ycgF E Lysine exporter protein LysE YggA
NLLAEHGB_00321 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
NLLAEHGB_00322 2.8e-261 mdr EGP Major facilitator Superfamily
NLLAEHGB_00323 1.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NLLAEHGB_00324 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NLLAEHGB_00325 6.3e-82 ycgB
NLLAEHGB_00326 3.1e-230 ycgA S Membrane
NLLAEHGB_00327 9.6e-211 amhX S amidohydrolase
NLLAEHGB_00328 6.9e-164 opuAC E glycine betaine
NLLAEHGB_00329 1.6e-138 opuAB P glycine betaine
NLLAEHGB_00330 3.9e-229 proV 3.6.3.32 E glycine betaine
NLLAEHGB_00331 2.1e-216 naiP P Uncharacterised MFS-type transporter YbfB
NLLAEHGB_00332 3.9e-193 yceH P Belongs to the TelA family
NLLAEHGB_00333 0.0 yceG S Putative component of 'biosynthetic module'
NLLAEHGB_00334 9.7e-138 terC P Protein of unknown function (DUF475)
NLLAEHGB_00335 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
NLLAEHGB_00336 8.2e-105 yceD T proteins involved in stress response, homologs of TerZ and
NLLAEHGB_00337 4.3e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NLLAEHGB_00338 3.3e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLLAEHGB_00339 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NLLAEHGB_00340 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NLLAEHGB_00341 1.8e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
NLLAEHGB_00342 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NLLAEHGB_00343 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
NLLAEHGB_00344 4.6e-189 S response regulator aspartate phosphatase
NLLAEHGB_00345 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
NLLAEHGB_00346 1.1e-266 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NLLAEHGB_00347 8.2e-260 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NLLAEHGB_00348 6.2e-177 ycdA S Domain of unknown function (DUF5105)
NLLAEHGB_00349 7.3e-172 yccK C Aldo keto reductase
NLLAEHGB_00350 1.3e-196 yccF K DNA-templated transcriptional preinitiation complex assembly
NLLAEHGB_00351 3.4e-112 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NLLAEHGB_00352 9.9e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NLLAEHGB_00353 1.2e-100 yxaF K Transcriptional regulator
NLLAEHGB_00354 1e-241 lmrB EGP the major facilitator superfamily
NLLAEHGB_00355 1.8e-209 ycbU E Selenocysteine lyase
NLLAEHGB_00356 7.7e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NLLAEHGB_00357 3.4e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NLLAEHGB_00358 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NLLAEHGB_00359 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NLLAEHGB_00360 2.5e-79 sleB 3.5.1.28 M Cell wall
NLLAEHGB_00361 5.6e-62 ycbP S Protein of unknown function (DUF2512)
NLLAEHGB_00362 1.6e-55 traF CO Thioredoxin
NLLAEHGB_00363 1.5e-62 mhqP S DoxX
NLLAEHGB_00364 1.4e-183 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NLLAEHGB_00365 3.7e-111 ydfN C nitroreductase
NLLAEHGB_00366 1.2e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLLAEHGB_00367 2.6e-18 L Transposase
NLLAEHGB_00368 1.8e-25 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NLLAEHGB_00369 1.9e-172 glnL T Regulator
NLLAEHGB_00370 7.6e-212 phoQ 2.7.13.3 T Histidine kinase
NLLAEHGB_00371 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
NLLAEHGB_00372 9.3e-259 agcS E Sodium alanine symporter
NLLAEHGB_00373 1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NLLAEHGB_00374 1e-257 mmuP E amino acid
NLLAEHGB_00375 1.2e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NLLAEHGB_00376 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NLLAEHGB_00377 1.9e-191 yceA S Belongs to the UPF0176 family
NLLAEHGB_00378 1.2e-42 ybfN
NLLAEHGB_00379 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NLLAEHGB_00380 1.9e-86 ybfM S SNARE associated Golgi protein
NLLAEHGB_00381 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NLLAEHGB_00382 1.1e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NLLAEHGB_00383 1.1e-200 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
NLLAEHGB_00384 1.2e-82 K Helix-turn-helix XRE-family like proteins
NLLAEHGB_00385 6e-31
NLLAEHGB_00386 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NLLAEHGB_00388 5e-212 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NLLAEHGB_00389 1.3e-16 S Protein of unknown function (DUF2651)
NLLAEHGB_00390 1.7e-259 glpT G -transporter
NLLAEHGB_00391 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NLLAEHGB_00392 3.4e-15 S Protein of unknown function (DUF2651)
NLLAEHGB_00393 1.1e-55
NLLAEHGB_00394 1.2e-291 ybeC E amino acid
NLLAEHGB_00395 9.2e-40 ybyB
NLLAEHGB_00396 2.8e-107 yqeB
NLLAEHGB_00397 2.2e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
NLLAEHGB_00398 4.5e-77 S Domain of unknown function (DUF4879)
NLLAEHGB_00399 1.6e-22
NLLAEHGB_00400 1e-196 V ABC-2 family transporter protein
NLLAEHGB_00401 9.8e-206 V COG0842 ABC-type multidrug transport system, permease component
NLLAEHGB_00402 4e-170 V COG1131 ABC-type multidrug transport system, ATPase component
NLLAEHGB_00403 1.9e-110 KT LuxR family transcriptional regulator
NLLAEHGB_00404 6.3e-202 T COG4585 Signal transduction histidine kinase
NLLAEHGB_00405 4.3e-45 K Acetyltransferase (GNAT) domain
NLLAEHGB_00406 2e-56 azoR I NADPH-dependent FMN reductase
NLLAEHGB_00407 6.2e-101 GM NAD(P)H-binding
NLLAEHGB_00408 5.3e-97 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NLLAEHGB_00409 3.3e-78 K Transcriptional regulator
NLLAEHGB_00410 5.5e-08
NLLAEHGB_00418 1.1e-56 ydcK S Belongs to the SprT family
NLLAEHGB_00419 6.5e-14
NLLAEHGB_00420 0.0 yhgF K COG2183 Transcriptional accessory protein
NLLAEHGB_00421 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NLLAEHGB_00422 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NLLAEHGB_00423 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NLLAEHGB_00424 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
NLLAEHGB_00425 4.6e-188 rsbU 3.1.3.3 KT phosphatase
NLLAEHGB_00426 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NLLAEHGB_00427 1.8e-57 rsbS T antagonist
NLLAEHGB_00428 6.1e-146 rsbR T Positive regulator of sigma-B
NLLAEHGB_00429 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NLLAEHGB_00430 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NLLAEHGB_00431 1.1e-217 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NLLAEHGB_00432 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NLLAEHGB_00433 4.3e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NLLAEHGB_00434 2.6e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NLLAEHGB_00435 1.7e-263 ydbT S Membrane
NLLAEHGB_00436 2.1e-82 ydbS S Bacterial PH domain
NLLAEHGB_00437 1.3e-250 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NLLAEHGB_00438 4.4e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NLLAEHGB_00439 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NLLAEHGB_00440 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NLLAEHGB_00441 3.1e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLLAEHGB_00442 5.8e-09 S Fur-regulated basic protein A
NLLAEHGB_00443 1.5e-10 S Fur-regulated basic protein B
NLLAEHGB_00444 1.1e-206 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NLLAEHGB_00445 2.1e-52 ydbL
NLLAEHGB_00446 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NLLAEHGB_00447 9.5e-172 ydbJ V ABC transporter, ATP-binding protein
NLLAEHGB_00448 2.1e-159 ydbI S AI-2E family transporter
NLLAEHGB_00449 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NLLAEHGB_00450 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
NLLAEHGB_00451 1.6e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NLLAEHGB_00452 7.1e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NLLAEHGB_00453 6.5e-156 ydbD P Catalase
NLLAEHGB_00454 5.9e-61 ydbC S Domain of unknown function (DUF4937
NLLAEHGB_00455 1.7e-57 ydbB G Cupin domain
NLLAEHGB_00457 1.8e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NLLAEHGB_00458 4.1e-54 yvaE P Small Multidrug Resistance protein
NLLAEHGB_00459 2.4e-71 yvaD S Family of unknown function (DUF5360)
NLLAEHGB_00460 1.9e-33 ydaT
NLLAEHGB_00462 3.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
NLLAEHGB_00463 2.1e-39
NLLAEHGB_00464 1.3e-99
NLLAEHGB_00465 1.4e-77
NLLAEHGB_00467 4.7e-11
NLLAEHGB_00469 1.7e-207 S Histidine kinase
NLLAEHGB_00470 2.8e-69
NLLAEHGB_00471 4.1e-86 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NLLAEHGB_00472 3.6e-37 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NLLAEHGB_00473 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NLLAEHGB_00474 2.7e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NLLAEHGB_00475 0.0 ydaO E amino acid
NLLAEHGB_00476 0.0 ydaN S Bacterial cellulose synthase subunit
NLLAEHGB_00477 8.5e-232 ydaM M Glycosyl transferase family group 2
NLLAEHGB_00478 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NLLAEHGB_00479 4.3e-147 ydaK T Diguanylate cyclase, GGDEF domain
NLLAEHGB_00480 2.7e-202 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NLLAEHGB_00481 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NLLAEHGB_00482 1.5e-74 lrpC K Transcriptional regulator
NLLAEHGB_00483 2.7e-48 ydzA EGP Major facilitator Superfamily
NLLAEHGB_00484 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NLLAEHGB_00485 1.4e-77 ydaG 1.4.3.5 S general stress protein
NLLAEHGB_00486 5e-116 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NLLAEHGB_00487 4.6e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NLLAEHGB_00488 3.7e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NLLAEHGB_00489 1.5e-288 ydaB IQ acyl-CoA ligase
NLLAEHGB_00490 0.0 mtlR K transcriptional regulator, MtlR
NLLAEHGB_00491 7.5e-174 ydhF S Oxidoreductase
NLLAEHGB_00492 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NLLAEHGB_00493 5.1e-56 yczJ S biosynthesis
NLLAEHGB_00495 9.3e-118 ycsK E anatomical structure formation involved in morphogenesis
NLLAEHGB_00496 4e-131 kipR K Transcriptional regulator
NLLAEHGB_00497 5.5e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NLLAEHGB_00498 6e-137 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NLLAEHGB_00499 1.4e-152 ycsI S Belongs to the D-glutamate cyclase family
NLLAEHGB_00500 3e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NLLAEHGB_00501 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
NLLAEHGB_00502 2.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NLLAEHGB_00504 3.9e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NLLAEHGB_00505 4.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NLLAEHGB_00506 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NLLAEHGB_00507 3.7e-223 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NLLAEHGB_00508 1.6e-55
NLLAEHGB_00509 2.5e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NLLAEHGB_00510 6.1e-299 ycnJ P protein, homolog of Cu resistance protein CopC
NLLAEHGB_00511 7.8e-98 ycnI S protein conserved in bacteria
NLLAEHGB_00512 4.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NLLAEHGB_00513 3.6e-149 glcU U Glucose uptake
NLLAEHGB_00514 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NLLAEHGB_00515 5.3e-221 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NLLAEHGB_00516 3.6e-263 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NLLAEHGB_00517 8.8e-53 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NLLAEHGB_00518 5.2e-44 ycnE S Monooxygenase
NLLAEHGB_00519 2.3e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
NLLAEHGB_00520 2.1e-152 ycnC K Transcriptional regulator
NLLAEHGB_00521 3.9e-249 ycnB EGP Major facilitator Superfamily
NLLAEHGB_00522 9.3e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NLLAEHGB_00523 8.1e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NLLAEHGB_00524 1e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLLAEHGB_00525 3e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLLAEHGB_00526 1.7e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
NLLAEHGB_00529 4e-79 S aspartate phosphatase
NLLAEHGB_00530 1.1e-262 T PhoQ Sensor
NLLAEHGB_00531 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLLAEHGB_00532 1e-236 yclI V ABC transporter (permease) YclI
NLLAEHGB_00533 3e-122 yclH P ABC transporter
NLLAEHGB_00534 2.4e-253 yxeQ S MmgE/PrpD family
NLLAEHGB_00535 3.4e-219 yxeP 3.5.1.47 E hydrolase activity
NLLAEHGB_00536 4.1e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NLLAEHGB_00537 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
NLLAEHGB_00538 4.6e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
NLLAEHGB_00539 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLLAEHGB_00540 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLLAEHGB_00541 5.1e-196 gerKB F Spore germination protein
NLLAEHGB_00542 5.5e-236 gerKC S spore germination
NLLAEHGB_00543 2.3e-285 gerKA EG Spore germination protein
NLLAEHGB_00545 1.2e-281 yclG M Pectate lyase superfamily protein
NLLAEHGB_00546 3.2e-270 dtpT E amino acid peptide transporter
NLLAEHGB_00547 7.3e-84 G SMI1-KNR4 cell-wall
NLLAEHGB_00548 5.9e-76 yokF 3.1.31.1 L RNA catabolic process
NLLAEHGB_00549 6.2e-307 yokA L Recombinase
NLLAEHGB_00550 2.3e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
NLLAEHGB_00551 3.6e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NLLAEHGB_00552 2.7e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLLAEHGB_00553 1.4e-66 ypoP K transcriptional
NLLAEHGB_00554 5.5e-98 ypmS S protein conserved in bacteria
NLLAEHGB_00555 4e-136 ypmR E GDSL-like Lipase/Acylhydrolase
NLLAEHGB_00556 3.2e-115 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NLLAEHGB_00557 2.6e-39 ypmP S Protein of unknown function (DUF2535)
NLLAEHGB_00558 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NLLAEHGB_00559 1.2e-180 pspF K Transcriptional regulator
NLLAEHGB_00560 9.3e-110 hlyIII S protein, Hemolysin III
NLLAEHGB_00561 5.5e-115 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NLLAEHGB_00562 1.6e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NLLAEHGB_00563 1.9e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NLLAEHGB_00564 2.7e-114 ypjP S YpjP-like protein
NLLAEHGB_00565 5.7e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NLLAEHGB_00566 1e-75 yphP S Belongs to the UPF0403 family
NLLAEHGB_00567 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NLLAEHGB_00568 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
NLLAEHGB_00569 6.3e-100 ypgQ S phosphohydrolase
NLLAEHGB_00570 1.1e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NLLAEHGB_00571 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NLLAEHGB_00572 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NLLAEHGB_00573 1e-30 cspD K Cold-shock protein
NLLAEHGB_00574 3.3e-12 degR
NLLAEHGB_00575 1.2e-36 S Protein of unknown function (DUF2564)
NLLAEHGB_00576 5.7e-28 ypeQ S Zinc-finger
NLLAEHGB_00577 2.4e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NLLAEHGB_00578 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NLLAEHGB_00579 1.7e-66 rnhA 3.1.26.4 L Ribonuclease
NLLAEHGB_00581 1.4e-164 polA 2.7.7.7 L 5'3' exonuclease
NLLAEHGB_00583 1.7e-38 ypbS S Protein of unknown function (DUF2533)
NLLAEHGB_00584 0.0 ypbR S Dynamin family
NLLAEHGB_00585 1.1e-89 ypbQ S protein conserved in bacteria
NLLAEHGB_00586 4.5e-205 bcsA Q Naringenin-chalcone synthase
NLLAEHGB_00587 1.2e-106 J Acetyltransferase (GNAT) domain
NLLAEHGB_00588 2.3e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
NLLAEHGB_00589 1.5e-08 S Bacillus cereus group antimicrobial protein
NLLAEHGB_00590 3.7e-97 ydfR S Protein of unknown function (DUF421)
NLLAEHGB_00591 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
NLLAEHGB_00593 2.7e-27 K Helix-turn-helix domain
NLLAEHGB_00594 2.7e-14 S Membrane
NLLAEHGB_00595 9.8e-86 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NLLAEHGB_00597 5.5e-07
NLLAEHGB_00598 2.4e-71 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NLLAEHGB_00599 4.6e-57 S Pfam:Phage_holin_4_1
NLLAEHGB_00601 2.4e-09
NLLAEHGB_00602 1.2e-93
NLLAEHGB_00603 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
NLLAEHGB_00604 4.1e-229 NU Prophage endopeptidase tail
NLLAEHGB_00605 5.9e-104 S Phage tail protein
NLLAEHGB_00606 0.0 D phage tail tape measure protein
NLLAEHGB_00608 2.4e-78 S Phage tail tube protein
NLLAEHGB_00610 1.1e-49 S Bacteriophage HK97-gp10, putative tail-component
NLLAEHGB_00611 5e-40 S Phage head-tail joining protein
NLLAEHGB_00612 1.1e-39 S Phage gp6-like head-tail connector protein
NLLAEHGB_00613 4.1e-23
NLLAEHGB_00614 1.6e-153 gp36 S capsid protein
NLLAEHGB_00615 6.6e-84 S peptidase activity
NLLAEHGB_00616 1.2e-169 S Phage portal protein
NLLAEHGB_00617 6.8e-309 S Terminase
NLLAEHGB_00618 1.1e-79 L phage terminase small subunit
NLLAEHGB_00620 4.9e-20
NLLAEHGB_00621 6.8e-17 K Transcriptional regulator
NLLAEHGB_00623 3.9e-12 K Transcriptional regulator
NLLAEHGB_00625 3.8e-53 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NLLAEHGB_00628 4.2e-71
NLLAEHGB_00629 9.2e-17
NLLAEHGB_00630 3.9e-28
NLLAEHGB_00632 3.4e-21 yqaO S Phage-like element PBSX protein XtrA
NLLAEHGB_00634 2.2e-59 rusA L Endodeoxyribonuclease RusA
NLLAEHGB_00636 4.8e-118 xkdC L IstB-like ATP binding protein
NLLAEHGB_00637 1.6e-78 3.1.3.16 L DnaD domain protein
NLLAEHGB_00639 1.7e-61 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NLLAEHGB_00640 2.1e-99
NLLAEHGB_00644 5.8e-87
NLLAEHGB_00645 1.1e-42 S Phage regulatory protein Rha (Phage_pRha)
NLLAEHGB_00646 3.8e-32
NLLAEHGB_00647 2.7e-16 K Helix-turn-helix XRE-family like proteins
NLLAEHGB_00648 6.1e-139 L Belongs to the 'phage' integrase family
NLLAEHGB_00649 1.4e-234 pbuX F xanthine
NLLAEHGB_00650 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NLLAEHGB_00651 1.2e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NLLAEHGB_00652 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NLLAEHGB_00654 6.6e-22 S YpzG-like protein
NLLAEHGB_00655 1.1e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NLLAEHGB_00656 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NLLAEHGB_00657 4.8e-99 ypsA S Belongs to the UPF0398 family
NLLAEHGB_00658 9.9e-33 cotD S Inner spore coat protein D
NLLAEHGB_00660 1.9e-236 yprB L RNase_H superfamily
NLLAEHGB_00661 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NLLAEHGB_00662 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NLLAEHGB_00663 1.7e-72 hspX O Belongs to the small heat shock protein (HSP20) family
NLLAEHGB_00664 3.4e-47 yppG S YppG-like protein
NLLAEHGB_00666 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
NLLAEHGB_00669 1.4e-186 yppC S Protein of unknown function (DUF2515)
NLLAEHGB_00670 1e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NLLAEHGB_00671 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NLLAEHGB_00672 1.1e-89 ypoC
NLLAEHGB_00673 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NLLAEHGB_00674 3e-130 dnaD L DNA replication protein DnaD
NLLAEHGB_00675 2.9e-251 asnS 6.1.1.22 J asparaginyl-tRNA
NLLAEHGB_00676 9.7e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NLLAEHGB_00677 4e-81 ypmB S protein conserved in bacteria
NLLAEHGB_00678 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NLLAEHGB_00679 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NLLAEHGB_00680 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NLLAEHGB_00681 7.2e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NLLAEHGB_00682 5.9e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NLLAEHGB_00683 1.3e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NLLAEHGB_00684 1e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NLLAEHGB_00685 1.8e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NLLAEHGB_00686 1.4e-130 bshB1 S proteins, LmbE homologs
NLLAEHGB_00687 4.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NLLAEHGB_00688 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NLLAEHGB_00689 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NLLAEHGB_00690 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NLLAEHGB_00691 1.2e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
NLLAEHGB_00692 4.3e-141 ypjB S sporulation protein
NLLAEHGB_00693 2.9e-105 ypjA S membrane
NLLAEHGB_00694 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NLLAEHGB_00695 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NLLAEHGB_00696 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NLLAEHGB_00697 3.2e-77 ypiF S Protein of unknown function (DUF2487)
NLLAEHGB_00698 2.1e-99 ypiB S Belongs to the UPF0302 family
NLLAEHGB_00699 1.7e-232 S COG0457 FOG TPR repeat
NLLAEHGB_00700 0.0 Q Polyketide synthase of type I
NLLAEHGB_00701 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
NLLAEHGB_00702 3.8e-212 V Beta-lactamase
NLLAEHGB_00703 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NLLAEHGB_00704 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NLLAEHGB_00705 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NLLAEHGB_00706 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NLLAEHGB_00707 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NLLAEHGB_00708 1.6e-138 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
NLLAEHGB_00709 7e-278 speA 4.1.1.19 E Arginine
NLLAEHGB_00710 1.6e-42 yktA S Belongs to the UPF0223 family
NLLAEHGB_00711 4.9e-119 yktB S Belongs to the UPF0637 family
NLLAEHGB_00712 6.3e-24 ykzI
NLLAEHGB_00713 6.1e-151 suhB 3.1.3.25 G Inositol monophosphatase
NLLAEHGB_00714 1.5e-82 ykzC S Acetyltransferase (GNAT) family
NLLAEHGB_00715 7.9e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NLLAEHGB_00716 6.3e-13 sigC S Putative zinc-finger
NLLAEHGB_00717 6.3e-39 ylaE
NLLAEHGB_00718 6.7e-24 S Family of unknown function (DUF5325)
NLLAEHGB_00719 0.0 typA T GTP-binding protein TypA
NLLAEHGB_00720 1.7e-48 ylaH S YlaH-like protein
NLLAEHGB_00721 1e-33 ylaI S protein conserved in bacteria
NLLAEHGB_00722 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NLLAEHGB_00723 3.7e-246 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NLLAEHGB_00724 2.9e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NLLAEHGB_00725 1.8e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
NLLAEHGB_00726 8.7e-44 ylaN S Belongs to the UPF0358 family
NLLAEHGB_00727 2.9e-213 ftsW D Belongs to the SEDS family
NLLAEHGB_00728 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NLLAEHGB_00729 1e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NLLAEHGB_00730 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NLLAEHGB_00731 4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NLLAEHGB_00732 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NLLAEHGB_00733 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NLLAEHGB_00734 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NLLAEHGB_00735 9.7e-166 ctaG S cytochrome c oxidase
NLLAEHGB_00736 8.5e-60 ylbA S YugN-like family
NLLAEHGB_00737 1.4e-72 ylbB T COG0517 FOG CBS domain
NLLAEHGB_00738 2.1e-199 ylbC S protein with SCP PR1 domains
NLLAEHGB_00739 1.3e-56 ylbD S Putative coat protein
NLLAEHGB_00740 8.8e-37 ylbE S YlbE-like protein
NLLAEHGB_00741 1.2e-71 ylbF S Belongs to the UPF0342 family
NLLAEHGB_00742 5.5e-43 ylbG S UPF0298 protein
NLLAEHGB_00744 8.5e-90 rsmD 2.1.1.171 L Methyltransferase
NLLAEHGB_00745 1.1e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NLLAEHGB_00746 9.8e-217 ylbJ S Sporulation integral membrane protein YlbJ
NLLAEHGB_00747 8.9e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
NLLAEHGB_00748 2.1e-188 ylbL T Belongs to the peptidase S16 family
NLLAEHGB_00749 7.1e-231 ylbM S Belongs to the UPF0348 family
NLLAEHGB_00750 2.7e-91 yceD S metal-binding, possibly nucleic acid-binding protein
NLLAEHGB_00751 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NLLAEHGB_00752 1.2e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NLLAEHGB_00753 1.2e-88 ylbP K n-acetyltransferase
NLLAEHGB_00754 7.7e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLLAEHGB_00755 2.3e-311 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NLLAEHGB_00756 8.9e-78 mraZ K Belongs to the MraZ family
NLLAEHGB_00757 3.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NLLAEHGB_00758 8.3e-52 ftsL D Essential cell division protein
NLLAEHGB_00759 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NLLAEHGB_00760 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NLLAEHGB_00761 1.7e-279 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NLLAEHGB_00762 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLLAEHGB_00763 7.7e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NLLAEHGB_00764 4.8e-185 spoVE D Belongs to the SEDS family
NLLAEHGB_00765 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NLLAEHGB_00766 3.7e-168 murB 1.3.1.98 M cell wall formation
NLLAEHGB_00767 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NLLAEHGB_00768 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NLLAEHGB_00769 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NLLAEHGB_00770 0.0 bpr O COG1404 Subtilisin-like serine proteases
NLLAEHGB_00771 4.1e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NLLAEHGB_00772 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NLLAEHGB_00773 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NLLAEHGB_00774 1.9e-144 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NLLAEHGB_00775 1.1e-255 argE 3.5.1.16 E Acetylornithine deacetylase
NLLAEHGB_00776 2.2e-38 ylmC S sporulation protein
NLLAEHGB_00777 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NLLAEHGB_00778 1.2e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NLLAEHGB_00779 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NLLAEHGB_00780 5.2e-41 yggT S membrane
NLLAEHGB_00781 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NLLAEHGB_00782 8.9e-68 divIVA D Cell division initiation protein
NLLAEHGB_00783 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NLLAEHGB_00784 3.4e-64 dksA T COG1734 DnaK suppressor protein
NLLAEHGB_00785 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NLLAEHGB_00786 2.3e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NLLAEHGB_00787 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NLLAEHGB_00788 8e-233 pyrP F Xanthine uracil
NLLAEHGB_00789 5.3e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NLLAEHGB_00790 1e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NLLAEHGB_00791 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NLLAEHGB_00792 0.0 carB 6.3.5.5 F Belongs to the CarB family
NLLAEHGB_00793 1.1e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NLLAEHGB_00794 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NLLAEHGB_00795 1.4e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NLLAEHGB_00796 4.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NLLAEHGB_00797 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NLLAEHGB_00798 1.7e-177 cysP P phosphate transporter
NLLAEHGB_00799 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NLLAEHGB_00800 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NLLAEHGB_00801 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NLLAEHGB_00802 6.4e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NLLAEHGB_00803 1.5e-80 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NLLAEHGB_00806 5.5e-89 ysnB S Phosphoesterase
NLLAEHGB_00807 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NLLAEHGB_00808 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NLLAEHGB_00809 2.4e-198 gerM S COG5401 Spore germination protein
NLLAEHGB_00810 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NLLAEHGB_00811 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NLLAEHGB_00812 2e-30 gerE K Transcriptional regulator
NLLAEHGB_00813 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NLLAEHGB_00814 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NLLAEHGB_00815 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NLLAEHGB_00816 4.8e-108 sdhC C succinate dehydrogenase
NLLAEHGB_00817 1.2e-79 yslB S Protein of unknown function (DUF2507)
NLLAEHGB_00818 4.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NLLAEHGB_00819 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NLLAEHGB_00820 2.5e-52 trxA O Belongs to the thioredoxin family
NLLAEHGB_00821 1.7e-303 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NLLAEHGB_00822 2.9e-179 etfA C Electron transfer flavoprotein
NLLAEHGB_00823 7.5e-138 etfB C Electron transfer flavoprotein
NLLAEHGB_00824 4.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NLLAEHGB_00825 9.2e-104 fadR K Transcriptional regulator
NLLAEHGB_00826 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NLLAEHGB_00827 4.1e-124 ywbB S Protein of unknown function (DUF2711)
NLLAEHGB_00828 4.7e-67 yshE S membrane
NLLAEHGB_00829 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NLLAEHGB_00830 0.0 polX L COG1796 DNA polymerase IV (family X)
NLLAEHGB_00831 1.1e-82 cvpA S membrane protein, required for colicin V production
NLLAEHGB_00832 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NLLAEHGB_00833 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLLAEHGB_00834 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLLAEHGB_00835 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NLLAEHGB_00836 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLLAEHGB_00837 2e-32 sspI S Belongs to the SspI family
NLLAEHGB_00838 5.8e-205 ysfB KT regulator
NLLAEHGB_00839 1.8e-259 glcD 1.1.3.15 C FAD binding domain
NLLAEHGB_00840 3.4e-255 glcF C Glycolate oxidase
NLLAEHGB_00841 0.0 cstA T Carbon starvation protein
NLLAEHGB_00842 1.2e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NLLAEHGB_00843 4.4e-144 araQ G transport system permease
NLLAEHGB_00844 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
NLLAEHGB_00845 1.8e-253 araN G carbohydrate transport
NLLAEHGB_00846 1.5e-225 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NLLAEHGB_00847 1.1e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NLLAEHGB_00848 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NLLAEHGB_00849 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NLLAEHGB_00850 1.1e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NLLAEHGB_00851 1.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NLLAEHGB_00852 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
NLLAEHGB_00853 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NLLAEHGB_00854 7.7e-42 ysdA S Membrane
NLLAEHGB_00855 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NLLAEHGB_00856 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NLLAEHGB_00857 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NLLAEHGB_00858 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NLLAEHGB_00859 4.1e-40 lrgA S effector of murein hydrolase LrgA
NLLAEHGB_00860 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
NLLAEHGB_00861 0.0 lytS 2.7.13.3 T Histidine kinase
NLLAEHGB_00862 7.9e-151 ysaA S HAD-hyrolase-like
NLLAEHGB_00863 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NLLAEHGB_00864 6.7e-153 ytxC S YtxC-like family
NLLAEHGB_00865 2.7e-109 ytxB S SNARE associated Golgi protein
NLLAEHGB_00866 4.3e-172 dnaI L Primosomal protein DnaI
NLLAEHGB_00867 4.2e-256 dnaB L Membrane attachment protein
NLLAEHGB_00868 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NLLAEHGB_00869 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NLLAEHGB_00870 3e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NLLAEHGB_00871 2e-67 ytcD K Transcriptional regulator
NLLAEHGB_00872 1.4e-204 ytbD EGP Major facilitator Superfamily
NLLAEHGB_00873 5.8e-160 ytbE S reductase
NLLAEHGB_00874 1.2e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NLLAEHGB_00875 2.1e-106 ytaF P Probably functions as a manganese efflux pump
NLLAEHGB_00876 4.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NLLAEHGB_00877 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLLAEHGB_00878 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NLLAEHGB_00879 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLLAEHGB_00880 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NLLAEHGB_00881 3.1e-242 icd 1.1.1.42 C isocitrate
NLLAEHGB_00882 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NLLAEHGB_00883 1.3e-103 S aspartate phosphatase
NLLAEHGB_00884 1.4e-34
NLLAEHGB_00885 1.6e-65
NLLAEHGB_00887 8.5e-48 yjdF S Protein of unknown function (DUF2992)
NLLAEHGB_00888 1.1e-72 yeaL S membrane
NLLAEHGB_00889 3.6e-194 ytvI S sporulation integral membrane protein YtvI
NLLAEHGB_00890 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NLLAEHGB_00891 7.5e-295 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NLLAEHGB_00892 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NLLAEHGB_00893 1.1e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NLLAEHGB_00894 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NLLAEHGB_00895 6.4e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
NLLAEHGB_00896 0.0 dnaE 2.7.7.7 L DNA polymerase
NLLAEHGB_00897 3.2e-56 ytrH S Sporulation protein YtrH
NLLAEHGB_00898 5.1e-87 ytrI
NLLAEHGB_00899 4.4e-23
NLLAEHGB_00900 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NLLAEHGB_00901 5.3e-47 ytpI S YtpI-like protein
NLLAEHGB_00902 1e-238 ytoI K transcriptional regulator containing CBS domains
NLLAEHGB_00903 2.8e-128 ytkL S Belongs to the UPF0173 family
NLLAEHGB_00904 4.5e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NLLAEHGB_00906 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
NLLAEHGB_00907 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NLLAEHGB_00908 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NLLAEHGB_00909 1.7e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NLLAEHGB_00910 1.5e-55 swrA S Swarming motility protein
NLLAEHGB_00911 4.2e-256 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NLLAEHGB_00912 1.6e-223 ywoF P Right handed beta helix region
NLLAEHGB_00913 1.7e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NLLAEHGB_00914 1e-122 ftsE D cell division ATP-binding protein FtsE
NLLAEHGB_00915 4e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
NLLAEHGB_00916 1e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NLLAEHGB_00917 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NLLAEHGB_00918 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NLLAEHGB_00919 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NLLAEHGB_00920 6.8e-68
NLLAEHGB_00921 2.6e-10 fliT S bacterial-type flagellum organization
NLLAEHGB_00922 3e-66 fliS N flagellar protein FliS
NLLAEHGB_00923 1.3e-247 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NLLAEHGB_00924 4.2e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NLLAEHGB_00925 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NLLAEHGB_00926 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NLLAEHGB_00927 1.4e-80 yviE
NLLAEHGB_00928 6.1e-163 flgL N Belongs to the bacterial flagellin family
NLLAEHGB_00929 1.1e-273 flgK N flagellar hook-associated protein
NLLAEHGB_00930 8.9e-81 flgN NOU FlgN protein
NLLAEHGB_00931 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
NLLAEHGB_00932 1.4e-74 yvyF S flagellar protein
NLLAEHGB_00933 2.9e-67 comFC S Phosphoribosyl transferase domain
NLLAEHGB_00934 1.5e-43 comFB S Late competence development protein ComFB
NLLAEHGB_00935 5.2e-259 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NLLAEHGB_00936 7.1e-158 degV S protein conserved in bacteria
NLLAEHGB_00937 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NLLAEHGB_00938 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NLLAEHGB_00939 2.2e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NLLAEHGB_00940 3e-173 yvhJ K Transcriptional regulator
NLLAEHGB_00941 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NLLAEHGB_00942 8.9e-239 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NLLAEHGB_00943 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
NLLAEHGB_00944 9.2e-116 tuaF M protein involved in exopolysaccharide biosynthesis
NLLAEHGB_00945 8.6e-257 tuaE M Teichuronic acid biosynthesis protein
NLLAEHGB_00946 2.1e-249 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NLLAEHGB_00947 6.2e-224 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NLLAEHGB_00948 2.3e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NLLAEHGB_00949 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NLLAEHGB_00950 5.4e-270 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NLLAEHGB_00951 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NLLAEHGB_00952 5.9e-49
NLLAEHGB_00953 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NLLAEHGB_00954 2.6e-211 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NLLAEHGB_00955 6.3e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NLLAEHGB_00956 8.9e-284 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NLLAEHGB_00957 1.7e-151 tagG GM Transport permease protein
NLLAEHGB_00958 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NLLAEHGB_00959 3.3e-294 M Glycosyltransferase like family 2
NLLAEHGB_00960 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NLLAEHGB_00961 2.6e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NLLAEHGB_00962 4e-220 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NLLAEHGB_00963 6.5e-242 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NLLAEHGB_00964 3.7e-187 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NLLAEHGB_00965 3.9e-265 gerBA EG Spore germination protein
NLLAEHGB_00966 6.4e-199 gerBB E Spore germination protein
NLLAEHGB_00967 1.4e-214 gerAC S Spore germination protein
NLLAEHGB_00968 7.3e-269 GT2,GT4 J Glycosyl transferase family 2
NLLAEHGB_00969 4.9e-249 ywtG EGP Major facilitator Superfamily
NLLAEHGB_00970 3.8e-179 ywtF K Transcriptional regulator
NLLAEHGB_00971 4.2e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NLLAEHGB_00972 2.5e-20 yttA 2.7.13.3 S Pfam Transposase IS66
NLLAEHGB_00973 6.3e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NLLAEHGB_00974 1.3e-20 ywtC
NLLAEHGB_00975 9.8e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NLLAEHGB_00976 2.3e-70 pgsC S biosynthesis protein
NLLAEHGB_00977 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NLLAEHGB_00978 7.7e-184 gerKA EG Spore germination protein
NLLAEHGB_00979 2.8e-191 gerKB E Spore germination protein
NLLAEHGB_00980 6.7e-204 gerKC S Spore germination B3/ GerAC like, C-terminal
NLLAEHGB_00981 7.2e-178 rbsR K transcriptional
NLLAEHGB_00982 3e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLLAEHGB_00983 2.1e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NLLAEHGB_00984 2.7e-277 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NLLAEHGB_00985 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NLLAEHGB_00986 2e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NLLAEHGB_00987 1.4e-90 batE T Sh3 type 3 domain protein
NLLAEHGB_00988 1.1e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
NLLAEHGB_00989 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NLLAEHGB_00990 1.2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NLLAEHGB_00991 9e-167 alsR K LysR substrate binding domain
NLLAEHGB_00993 1.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NLLAEHGB_00994 4.4e-126 ywrJ
NLLAEHGB_00995 9.2e-132 cotB
NLLAEHGB_00996 4.5e-213 cotH M Spore Coat
NLLAEHGB_00997 2.2e-09
NLLAEHGB_00998 5.6e-112 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NLLAEHGB_00999 1.4e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NLLAEHGB_01000 1.1e-83 ywrC K Transcriptional regulator
NLLAEHGB_01001 5.4e-104 ywrB P Chromate transporter
NLLAEHGB_01002 4.4e-89 ywrA P COG2059 Chromate transport protein ChrA
NLLAEHGB_01003 3.2e-135 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NLLAEHGB_01004 4.7e-93
NLLAEHGB_01005 2.8e-65 S SMI1 / KNR4 family (SUKH-1)
NLLAEHGB_01006 3.8e-104 S Domain of unknown function (DUF1851)
NLLAEHGB_01007 2.8e-79 S LXG domain of WXG superfamily
NLLAEHGB_01008 1.4e-23 ssuC P ABC transporter (permease)
NLLAEHGB_01009 1.7e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NLLAEHGB_01010 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLLAEHGB_01011 3e-81 ygaO
NLLAEHGB_01012 4.8e-23 K Transcriptional regulator
NLLAEHGB_01014 4.8e-111 yhzB S B3/4 domain
NLLAEHGB_01015 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NLLAEHGB_01016 4.8e-176 yhbB S Putative amidase domain
NLLAEHGB_01017 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NLLAEHGB_01018 3e-108 yhbD K Protein of unknown function (DUF4004)
NLLAEHGB_01019 1.9e-63 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NLLAEHGB_01020 1.3e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NLLAEHGB_01022 0.0 prkA T Ser protein kinase
NLLAEHGB_01023 1.4e-215 yhbH S Belongs to the UPF0229 family
NLLAEHGB_01024 4.6e-74 yhbI K DNA-binding transcription factor activity
NLLAEHGB_01025 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
NLLAEHGB_01026 8.4e-285 yhcA EGP Major facilitator Superfamily
NLLAEHGB_01027 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
NLLAEHGB_01028 3.8e-55 yhcC
NLLAEHGB_01029 3.6e-52
NLLAEHGB_01030 2.5e-62 yhcF K Transcriptional regulator
NLLAEHGB_01031 1e-125 yhcG V ABC transporter, ATP-binding protein
NLLAEHGB_01032 4.1e-167 yhcH V ABC transporter, ATP-binding protein
NLLAEHGB_01033 7.4e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NLLAEHGB_01034 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
NLLAEHGB_01035 4.2e-147 metQ M Belongs to the nlpA lipoprotein family
NLLAEHGB_01036 1.9e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NLLAEHGB_01037 9.2e-221 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NLLAEHGB_01038 3.8e-55 yhcM
NLLAEHGB_01039 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NLLAEHGB_01040 6e-163 yhcP
NLLAEHGB_01041 3.4e-115 yhcQ M Spore coat protein
NLLAEHGB_01042 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
NLLAEHGB_01043 2.8e-108 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NLLAEHGB_01044 1.1e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NLLAEHGB_01045 5.5e-65 yhcU S Family of unknown function (DUF5365)
NLLAEHGB_01046 7.6e-68 yhcV S COG0517 FOG CBS domain
NLLAEHGB_01047 5.5e-124 yhcW 5.4.2.6 S hydrolase
NLLAEHGB_01048 1.1e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NLLAEHGB_01049 1.9e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NLLAEHGB_01050 1.5e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NLLAEHGB_01051 4.5e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NLLAEHGB_01052 7e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NLLAEHGB_01053 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NLLAEHGB_01054 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NLLAEHGB_01055 1.3e-207 yhcY 2.7.13.3 T Histidine kinase
NLLAEHGB_01056 2e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NLLAEHGB_01057 8.8e-90 azr 1.7.1.6 S NADPH-dependent FMN reductase
NLLAEHGB_01058 2.5e-39 yhdB S YhdB-like protein
NLLAEHGB_01059 1.1e-53 yhdC S Protein of unknown function (DUF3889)
NLLAEHGB_01060 4e-217 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NLLAEHGB_01061 1.9e-74 nsrR K Transcriptional regulator
NLLAEHGB_01062 1.2e-256 ygxB M Conserved TM helix
NLLAEHGB_01063 1.3e-270 ycgB S Stage V sporulation protein R
NLLAEHGB_01064 3.7e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NLLAEHGB_01065 3.3e-128 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NLLAEHGB_01066 9e-164 citR K Transcriptional regulator
NLLAEHGB_01067 9.2e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
NLLAEHGB_01068 5.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NLLAEHGB_01069 4.1e-251 yhdG E amino acid
NLLAEHGB_01070 4.4e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NLLAEHGB_01071 8.1e-45 yhdK S Sigma-M inhibitor protein
NLLAEHGB_01072 1.3e-201 yhdL S Sigma factor regulator N-terminal
NLLAEHGB_01073 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NLLAEHGB_01074 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NLLAEHGB_01075 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NLLAEHGB_01076 4.3e-71 cueR K transcriptional
NLLAEHGB_01077 4.7e-224 yhdR 2.6.1.1 E Aminotransferase
NLLAEHGB_01078 2.3e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NLLAEHGB_01079 1.1e-256 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NLLAEHGB_01080 8.5e-52 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLLAEHGB_01081 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLLAEHGB_01082 1.7e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NLLAEHGB_01084 1.6e-205 yhdY M Mechanosensitive ion channel
NLLAEHGB_01085 4.5e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NLLAEHGB_01086 9.3e-158 yheN G deacetylase
NLLAEHGB_01087 1.6e-154 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NLLAEHGB_01088 4.6e-88 pksA K Transcriptional regulator
NLLAEHGB_01089 1.2e-94 ymcC S Membrane
NLLAEHGB_01090 2.1e-85 T universal stress protein
NLLAEHGB_01092 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NLLAEHGB_01093 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NLLAEHGB_01094 2.5e-112 yheG GM NAD(P)H-binding
NLLAEHGB_01096 5.8e-29 sspB S spore protein
NLLAEHGB_01097 1.7e-36 yheE S Family of unknown function (DUF5342)
NLLAEHGB_01098 2.5e-261 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NLLAEHGB_01099 4.8e-215 yheC HJ YheC/D like ATP-grasp
NLLAEHGB_01100 7.2e-206 yheB S Belongs to the UPF0754 family
NLLAEHGB_01101 4.4e-53 yheA S Belongs to the UPF0342 family
NLLAEHGB_01102 3.6e-205 yhaZ L DNA alkylation repair enzyme
NLLAEHGB_01103 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
NLLAEHGB_01104 1.6e-293 hemZ H coproporphyrinogen III oxidase
NLLAEHGB_01105 9.2e-250 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
NLLAEHGB_01106 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NLLAEHGB_01107 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NLLAEHGB_01109 3.4e-135 yhaR 5.3.3.18 I enoyl-CoA hydratase
NLLAEHGB_01110 5.6e-15 S YhzD-like protein
NLLAEHGB_01111 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
NLLAEHGB_01112 1.6e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NLLAEHGB_01113 7.7e-238 yhaO L DNA repair exonuclease
NLLAEHGB_01114 0.0 yhaN L AAA domain
NLLAEHGB_01115 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NLLAEHGB_01116 1.6e-32 yhaL S Sporulation protein YhaL
NLLAEHGB_01117 2.9e-42 bacT Q Thioesterase domain
NLLAEHGB_01118 1.9e-226 yvkA EGP Major facilitator Superfamily
NLLAEHGB_01119 7e-110 yvkB K Transcriptional regulator
NLLAEHGB_01120 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NLLAEHGB_01121 7.6e-33 csbA S protein conserved in bacteria
NLLAEHGB_01122 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NLLAEHGB_01123 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NLLAEHGB_01124 3e-38 yvkN
NLLAEHGB_01125 6.1e-49 yvlA
NLLAEHGB_01126 3.2e-166 yvlB S Putative adhesin
NLLAEHGB_01127 9.6e-26 pspB KT PspC domain
NLLAEHGB_01128 3.9e-41 yvlD S Membrane
NLLAEHGB_01129 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NLLAEHGB_01130 4.7e-105 yxaF K Transcriptional regulator
NLLAEHGB_01131 1.1e-133 yvoA K transcriptional
NLLAEHGB_01132 8e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NLLAEHGB_01133 1.7e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NLLAEHGB_01134 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NLLAEHGB_01135 2e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NLLAEHGB_01136 2.4e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NLLAEHGB_01137 1.9e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NLLAEHGB_01138 2e-137 yvpB NU protein conserved in bacteria
NLLAEHGB_01139 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NLLAEHGB_01140 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NLLAEHGB_01141 1e-235 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NLLAEHGB_01142 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NLLAEHGB_01143 1.5e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NLLAEHGB_01144 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NLLAEHGB_01145 1.1e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NLLAEHGB_01146 5.6e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NLLAEHGB_01147 0.0 msbA2 3.6.3.44 V ABC transporter
NLLAEHGB_01148 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLLAEHGB_01149 3.2e-192 sasA T Histidine kinase
NLLAEHGB_01150 5e-276 S COG0457 FOG TPR repeat
NLLAEHGB_01151 5e-124 usp CBM50 M protein conserved in bacteria
NLLAEHGB_01152 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NLLAEHGB_01153 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NLLAEHGB_01154 1.1e-166 rapZ S Displays ATPase and GTPase activities
NLLAEHGB_01155 1.9e-175 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NLLAEHGB_01156 3.1e-170 whiA K May be required for sporulation
NLLAEHGB_01157 4.7e-36 crh G Phosphocarrier protein Chr
NLLAEHGB_01158 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NLLAEHGB_01159 1.6e-79 M Ribonuclease
NLLAEHGB_01160 3.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLLAEHGB_01161 3.7e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NLLAEHGB_01162 3.3e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NLLAEHGB_01163 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
NLLAEHGB_01164 7.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NLLAEHGB_01165 7.5e-250 EGP Sugar (and other) transporter
NLLAEHGB_01166 4.9e-215 yraM S PrpF protein
NLLAEHGB_01167 6.7e-164 yraN K Transcriptional regulator
NLLAEHGB_01168 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NLLAEHGB_01169 7.3e-183 scrR K transcriptional
NLLAEHGB_01170 4.7e-219 rafB P LacY proton/sugar symporter
NLLAEHGB_01171 6.7e-297 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
NLLAEHGB_01173 3.1e-34
NLLAEHGB_01174 2.2e-236 I Pfam Lipase (class 3)
NLLAEHGB_01175 9.2e-25 S Protein of unknown function (DUF1433)
NLLAEHGB_01176 9.8e-20 S Protein of unknown function (DUF1433)
NLLAEHGB_01177 6.3e-13 S Protein of unknown function (DUF1433)
NLLAEHGB_01178 5.7e-53 MA20_18690 S Protein of unknown function (DUF3237)
NLLAEHGB_01179 4.6e-93 padC Q Phenolic acid decarboxylase
NLLAEHGB_01180 5.6e-89 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLLAEHGB_01181 1.3e-111 yyaS S Membrane
NLLAEHGB_01182 1.3e-96 ywjB H RibD C-terminal domain
NLLAEHGB_01184 3.2e-275 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NLLAEHGB_01185 1.9e-77 slr K transcriptional
NLLAEHGB_01186 8.4e-120 ywqC M biosynthesis protein
NLLAEHGB_01187 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NLLAEHGB_01188 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NLLAEHGB_01189 2.6e-219 epsD GT4 M Glycosyl transferase 4-like
NLLAEHGB_01190 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NLLAEHGB_01191 2e-216 epsF GT4 M Glycosyl transferases group 1
NLLAEHGB_01192 1e-204 epsG S EpsG family
NLLAEHGB_01193 1.5e-194 epsH GT2 S Glycosyltransferase like family 2
NLLAEHGB_01194 2.9e-204 epsI GM pyruvyl transferase
NLLAEHGB_01195 1.2e-196 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NLLAEHGB_01196 1.8e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NLLAEHGB_01197 7e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NLLAEHGB_01198 5.6e-54 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NLLAEHGB_01199 5.7e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NLLAEHGB_01200 8.9e-189 yvfF GM Exopolysaccharide biosynthesis protein
NLLAEHGB_01201 2.7e-32 yvfG S YvfG protein
NLLAEHGB_01202 2.6e-244 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NLLAEHGB_01203 1.9e-303 yvfH C L-lactate permease
NLLAEHGB_01204 1.3e-120 yvfI K COG2186 Transcriptional regulators
NLLAEHGB_01205 4.7e-224 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NLLAEHGB_01206 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NLLAEHGB_01207 4.7e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NLLAEHGB_01208 1.8e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NLLAEHGB_01209 2.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
NLLAEHGB_01210 9.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
NLLAEHGB_01211 7.7e-152 ybbH_1 K RpiR family transcriptional regulator
NLLAEHGB_01212 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
NLLAEHGB_01213 4e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLLAEHGB_01214 6.6e-185 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLLAEHGB_01215 8.9e-178 fhuD P ABC transporter
NLLAEHGB_01216 1.3e-236 yvsH E Arginine ornithine antiporter
NLLAEHGB_01217 3.6e-14 S Small spore protein J (Spore_SspJ)
NLLAEHGB_01218 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NLLAEHGB_01219 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NLLAEHGB_01220 1.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NLLAEHGB_01221 5.3e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NLLAEHGB_01222 1e-98 modB P COG4149 ABC-type molybdate transport system, permease component
NLLAEHGB_01223 4.4e-115 yfiK K Regulator
NLLAEHGB_01224 5.1e-180 T Histidine kinase
NLLAEHGB_01225 7.3e-172 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
NLLAEHGB_01226 2e-192 yfiM V ABC-2 type transporter
NLLAEHGB_01227 1e-199 yfiN V COG0842 ABC-type multidrug transport system, permease component
NLLAEHGB_01228 5e-156 yvgN S reductase
NLLAEHGB_01229 4.9e-87 yvgO
NLLAEHGB_01230 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NLLAEHGB_01231 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NLLAEHGB_01232 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NLLAEHGB_01233 0.0 helD 3.6.4.12 L DNA helicase
NLLAEHGB_01234 3.1e-99 yvgT S membrane
NLLAEHGB_01235 2.6e-141 S Metallo-peptidase family M12
NLLAEHGB_01236 6e-73 bdbC O Required for disulfide bond formation in some proteins
NLLAEHGB_01237 4.1e-100 bdbD O Thioredoxin
NLLAEHGB_01238 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NLLAEHGB_01239 0.0 copA 3.6.3.54 P P-type ATPase
NLLAEHGB_01240 2.6e-29 copZ P Heavy-metal-associated domain
NLLAEHGB_01241 1.1e-47 csoR S transcriptional
NLLAEHGB_01242 6.2e-196 yvaA 1.1.1.371 S Oxidoreductase
NLLAEHGB_01243 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NLLAEHGB_01244 4.3e-163 K Helix-turn-helix XRE-family like proteins
NLLAEHGB_01245 7.9e-219 ynfM EGP Major Facilitator Superfamily
NLLAEHGB_01246 4.7e-70 4.1.1.44 S Carboxymuconolactone decarboxylase family
NLLAEHGB_01247 6.8e-147 S Amidohydrolase
NLLAEHGB_01248 4e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLLAEHGB_01249 5.9e-48 ytnI O COG0695 Glutaredoxin and related proteins
NLLAEHGB_01250 2.9e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLLAEHGB_01251 2.1e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NLLAEHGB_01252 9.3e-119 tcyM U Binding-protein-dependent transport system inner membrane component
NLLAEHGB_01253 2.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
NLLAEHGB_01254 6.4e-148 tcyK M Bacterial periplasmic substrate-binding proteins
NLLAEHGB_01255 8.4e-132 ytmJ ET Bacterial periplasmic substrate-binding proteins
NLLAEHGB_01256 3e-101 ytmI K Acetyltransferase (GNAT) domain
NLLAEHGB_01257 4.8e-165 ytlI K LysR substrate binding domain
NLLAEHGB_01258 6.9e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NLLAEHGB_01259 2.5e-52 yrdF K ribonuclease inhibitor
NLLAEHGB_01261 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NLLAEHGB_01262 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NLLAEHGB_01263 7.4e-143 est 3.1.1.1 S Carboxylesterase
NLLAEHGB_01264 4.8e-24 secG U Preprotein translocase subunit SecG
NLLAEHGB_01265 6e-35 yvzC K Transcriptional
NLLAEHGB_01266 1e-69 K transcriptional
NLLAEHGB_01267 2.3e-72 yvaO K Cro/C1-type HTH DNA-binding domain
NLLAEHGB_01268 8.8e-53 yodB K transcriptional
NLLAEHGB_01269 1.8e-259 T His Kinase A (phosphoacceptor) domain
NLLAEHGB_01270 2e-123 K Transcriptional regulatory protein, C terminal
NLLAEHGB_01271 1.3e-137 mutG S ABC-2 family transporter protein
NLLAEHGB_01272 1.7e-123 spaE S ABC-2 family transporter protein
NLLAEHGB_01273 1.2e-126 mutF V ABC transporter, ATP-binding protein
NLLAEHGB_01274 2.3e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NLLAEHGB_01275 1.7e-173 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NLLAEHGB_01276 5.4e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NLLAEHGB_01277 1.8e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NLLAEHGB_01278 4.3e-76 yvbF K Belongs to the GbsR family
NLLAEHGB_01279 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NLLAEHGB_01280 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NLLAEHGB_01281 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NLLAEHGB_01282 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NLLAEHGB_01283 1.9e-98 yvbF K Belongs to the GbsR family
NLLAEHGB_01284 5.2e-105 yvbG U UPF0056 membrane protein
NLLAEHGB_01285 1.3e-120 exoY M Membrane
NLLAEHGB_01286 0.0 tcaA S response to antibiotic
NLLAEHGB_01287 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
NLLAEHGB_01288 1.5e-212 EGP Major facilitator Superfamily
NLLAEHGB_01289 1.1e-180
NLLAEHGB_01290 9.8e-126 S GlcNAc-PI de-N-acetylase
NLLAEHGB_01291 7.3e-143 C WbqC-like protein family
NLLAEHGB_01292 4.9e-149 M Protein involved in cellulose biosynthesis
NLLAEHGB_01293 5.7e-236 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NLLAEHGB_01294 1.2e-171 5.1.3.2 M GDP-mannose 4,6 dehydratase
NLLAEHGB_01295 1.1e-217 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NLLAEHGB_01296 1.8e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NLLAEHGB_01297 2.5e-239 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NLLAEHGB_01298 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NLLAEHGB_01299 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NLLAEHGB_01300 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NLLAEHGB_01301 5e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NLLAEHGB_01302 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NLLAEHGB_01303 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NLLAEHGB_01305 7.4e-253 araE EGP Major facilitator Superfamily
NLLAEHGB_01306 1.3e-204 araR K transcriptional
NLLAEHGB_01307 1.1e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLLAEHGB_01310 2.9e-252 iolT EGP Major facilitator Superfamily
NLLAEHGB_01311 1.8e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
NLLAEHGB_01312 2.3e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NLLAEHGB_01313 3.2e-166 ydhU P Catalase
NLLAEHGB_01314 9.3e-297 yveA E amino acid
NLLAEHGB_01315 5.3e-104 yvdT K Transcriptional regulator
NLLAEHGB_01316 2.3e-51 ykkC P Small Multidrug Resistance protein
NLLAEHGB_01317 2.2e-48 sugE P Small Multidrug Resistance protein
NLLAEHGB_01318 1.7e-216 yeaN P COG2807 Cyanate permease
NLLAEHGB_01319 2.2e-117 K FCD
NLLAEHGB_01320 1.3e-133 ydhQ K UTRA
NLLAEHGB_01321 1.2e-195 pbuE EGP Major facilitator Superfamily
NLLAEHGB_01322 2.5e-98 ydhK M Protein of unknown function (DUF1541)
NLLAEHGB_01324 2.2e-265 pbpE V Beta-lactamase
NLLAEHGB_01327 3.7e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NLLAEHGB_01328 4.8e-120 ydhC K FCD
NLLAEHGB_01329 4.7e-22 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NLLAEHGB_01330 1.5e-142 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NLLAEHGB_01331 7.5e-146 ycgJ_1 Q ubiE/COQ5 methyltransferase family
NLLAEHGB_01332 2.7e-114 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NLLAEHGB_01333 3.6e-149 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NLLAEHGB_01334 4.1e-150 bltR K helix_turn_helix, mercury resistance
NLLAEHGB_01335 2.9e-81 bltD 2.3.1.57 K FR47-like protein
NLLAEHGB_01336 5.9e-127 ydhB S membrane transporter protein
NLLAEHGB_01337 1.5e-155 K Helix-turn-helix XRE-family like proteins
NLLAEHGB_01338 3.4e-225 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NLLAEHGB_01339 3.9e-210 tcaB EGP Major facilitator Superfamily
NLLAEHGB_01340 3.5e-197 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
NLLAEHGB_01341 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
NLLAEHGB_01342 1.9e-100 ynaD J Acetyltransferase (GNAT) domain
NLLAEHGB_01343 3e-298 expZ S ABC transporter
NLLAEHGB_01344 2.5e-134 puuD S Peptidase C26
NLLAEHGB_01345 0.0 ydfJ S drug exporters of the RND superfamily
NLLAEHGB_01346 1.1e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NLLAEHGB_01347 1.2e-220 ydfH 2.7.13.3 T Histidine kinase
NLLAEHGB_01348 1.2e-36 yraG
NLLAEHGB_01349 3.8e-63 yraF M Spore coat protein
NLLAEHGB_01350 6.1e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NLLAEHGB_01351 2.8e-25 yraE
NLLAEHGB_01352 5.6e-49 yraD M Spore coat protein
NLLAEHGB_01353 7.6e-266 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NLLAEHGB_01354 3.7e-157 ydeK EG -transporter
NLLAEHGB_01355 1.3e-102 ydeS K Transcriptional regulator
NLLAEHGB_01356 1.4e-180 ydeR EGP Major facilitator Superfamily
NLLAEHGB_01358 3.5e-114 paiB K Transcriptional regulator
NLLAEHGB_01359 6e-263 K helix_turn_helix gluconate operon transcriptional repressor
NLLAEHGB_01360 2.1e-225 mleN_2 C antiporter
NLLAEHGB_01361 6.9e-50 yraB K helix_turn_helix, mercury resistance
NLLAEHGB_01362 1.2e-202 adhA 1.1.1.1 C alcohol dehydrogenase
NLLAEHGB_01363 1.1e-165 S Sodium Bile acid symporter family
NLLAEHGB_01364 3.4e-233 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NLLAEHGB_01365 1.7e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NLLAEHGB_01366 3e-147 Q ubiE/COQ5 methyltransferase family
NLLAEHGB_01367 6.6e-195 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NLLAEHGB_01368 3.7e-84 F nucleoside 2-deoxyribosyltransferase
NLLAEHGB_01369 3e-55 ydeH
NLLAEHGB_01370 7.1e-200 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
NLLAEHGB_01372 5.1e-150 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
NLLAEHGB_01373 1.3e-85 ykkA S Protein of unknown function (DUF664)
NLLAEHGB_01374 4.7e-99 yrkC G Cupin domain
NLLAEHGB_01376 4.4e-202 trkA P Oxidoreductase
NLLAEHGB_01377 4.3e-164 czcD P COG1230 Co Zn Cd efflux system component
NLLAEHGB_01378 2.3e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
NLLAEHGB_01380 7.5e-64 G Cupin domain
NLLAEHGB_01381 3.8e-84 S DinB superfamily
NLLAEHGB_01382 5.6e-183 S Patatin-like phospholipase
NLLAEHGB_01383 1.3e-51 K Transcriptional regulator PadR-like family
NLLAEHGB_01384 2.6e-103 S Protein of unknown function (DUF2812)
NLLAEHGB_01385 1.5e-121 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NLLAEHGB_01386 6.2e-116 yrkJ S membrane transporter protein
NLLAEHGB_01387 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
NLLAEHGB_01388 4.6e-197 yrkH P Rhodanese Homology Domain
NLLAEHGB_01389 3.8e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
NLLAEHGB_01390 1.3e-58 P Rhodanese Homology Domain
NLLAEHGB_01391 1.1e-83 yrkE O DsrE/DsrF/DrsH-like family
NLLAEHGB_01392 9.2e-40 yrkD S protein conserved in bacteria
NLLAEHGB_01393 8e-79 carD K Transcription factor
NLLAEHGB_01394 1.4e-30 cspL K Cold shock
NLLAEHGB_01395 3.8e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NLLAEHGB_01396 7.2e-47 K Transcriptional regulator
NLLAEHGB_01397 2.4e-178 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NLLAEHGB_01398 5.7e-186 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NLLAEHGB_01399 9.1e-133 C Enoyl-(Acyl carrier protein) reductase
NLLAEHGB_01400 1.9e-101 K Bacterial regulatory proteins, tetR family
NLLAEHGB_01401 4.2e-110 ywnB S NAD(P)H-binding
NLLAEHGB_01402 4.8e-73 ywnA K Transcriptional regulator
NLLAEHGB_01403 4.5e-63 yyaQ S YjbR
NLLAEHGB_01404 1e-72 maoC I N-terminal half of MaoC dehydratase
NLLAEHGB_01405 3.3e-80 S Domain of unknown function with cystatin-like fold (DUF4467)
NLLAEHGB_01406 1.1e-47 ohrR K Transcriptional regulator
NLLAEHGB_01407 8.8e-230 proP EGP Transporter
NLLAEHGB_01408 2.5e-152 S Serine aminopeptidase, S33
NLLAEHGB_01409 6.3e-165 ygxA S Nucleotidyltransferase-like
NLLAEHGB_01410 1.5e-56 ygzB S UPF0295 protein
NLLAEHGB_01411 1.8e-80 perR P Belongs to the Fur family
NLLAEHGB_01412 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
NLLAEHGB_01413 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NLLAEHGB_01414 3.2e-179 ygaE S Membrane
NLLAEHGB_01415 2.5e-306 ygaD V ABC transporter
NLLAEHGB_01416 2.2e-104 ygaC J Belongs to the UPF0374 family
NLLAEHGB_01417 1.5e-37 ygaB S YgaB-like protein
NLLAEHGB_01419 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NLLAEHGB_01420 1.8e-36 yfhS
NLLAEHGB_01421 1.3e-207 mutY L A G-specific
NLLAEHGB_01422 1e-184 yfhP S membrane-bound metal-dependent
NLLAEHGB_01423 0.0 yfhO S Bacterial membrane protein YfhO
NLLAEHGB_01424 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NLLAEHGB_01425 4.4e-171 yfhM S Alpha/beta hydrolase family
NLLAEHGB_01426 1.5e-34 yfhL S SdpI/YhfL protein family
NLLAEHGB_01427 1.6e-94 batE T Bacterial SH3 domain homologues
NLLAEHGB_01428 2.9e-44 yfhJ S WVELL protein
NLLAEHGB_01429 4.5e-166 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NLLAEHGB_01431 1.5e-206 yfhI EGP Major facilitator Superfamily
NLLAEHGB_01432 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NLLAEHGB_01433 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NLLAEHGB_01434 3.3e-169 yfhF S nucleoside-diphosphate sugar epimerase
NLLAEHGB_01435 2.1e-25 yfhD S YfhD-like protein
NLLAEHGB_01436 9.7e-106 yfhC C nitroreductase
NLLAEHGB_01437 3.3e-166 yfhB 5.3.3.17 S PhzF family
NLLAEHGB_01438 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NLLAEHGB_01439 2.8e-82 yfiV K transcriptional
NLLAEHGB_01440 1.7e-290 yfiU EGP Major facilitator Superfamily
NLLAEHGB_01441 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
NLLAEHGB_01442 1.5e-45 yrdF K ribonuclease inhibitor
NLLAEHGB_01443 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
NLLAEHGB_01444 1.1e-182 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NLLAEHGB_01445 4.2e-112 1.6.5.2 S NADPH-dependent FMN reductase
NLLAEHGB_01446 3e-96 padR K transcriptional
NLLAEHGB_01447 4.5e-169 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NLLAEHGB_01448 8.5e-159 yfiE 1.13.11.2 S glyoxalase
NLLAEHGB_01449 2.4e-63 mhqP S DoxX
NLLAEHGB_01450 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NLLAEHGB_01451 0.0 yfiB3 V ABC transporter
NLLAEHGB_01452 0.0 yobO M COG5434 Endopolygalacturonase
NLLAEHGB_01453 1e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NLLAEHGB_01454 2.1e-137 glvR F Helix-turn-helix domain, rpiR family
NLLAEHGB_01455 3.4e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NLLAEHGB_01456 4.2e-15 sspH S Belongs to the SspH family
NLLAEHGB_01457 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NLLAEHGB_01458 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NLLAEHGB_01459 3.7e-213 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NLLAEHGB_01460 1.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NLLAEHGB_01461 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NLLAEHGB_01462 7.2e-91 yfjM S Psort location Cytoplasmic, score
NLLAEHGB_01463 7.9e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLLAEHGB_01464 2.6e-60 M1-386
NLLAEHGB_01466 5.6e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLLAEHGB_01467 1.5e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NLLAEHGB_01468 3.8e-184 corA P Mediates influx of magnesium ions
NLLAEHGB_01469 3.2e-33
NLLAEHGB_01470 2.1e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NLLAEHGB_01471 9e-155 pdaA G deacetylase
NLLAEHGB_01472 4.9e-27 yfjT
NLLAEHGB_01473 1.3e-220 yfkA S YfkB-like domain
NLLAEHGB_01474 3.3e-147 yfkC M Mechanosensitive ion channel
NLLAEHGB_01475 2.5e-144 yfkD S YfkD-like protein
NLLAEHGB_01476 1.3e-185 cax P COG0387 Ca2 H antiporter
NLLAEHGB_01477 3.2e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NLLAEHGB_01478 2.5e-07
NLLAEHGB_01479 6.8e-145 yihY S Belongs to the UPF0761 family
NLLAEHGB_01480 4.5e-52 yfkI S gas vesicle protein
NLLAEHGB_01481 9e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NLLAEHGB_01482 2.7e-29 yfkK S Belongs to the UPF0435 family
NLLAEHGB_01483 1.3e-183 ydiM EGP Major facilitator Superfamily
NLLAEHGB_01484 4.5e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NLLAEHGB_01485 1.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NLLAEHGB_01486 4.4e-186 K helix_turn _helix lactose operon repressor
NLLAEHGB_01487 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
NLLAEHGB_01488 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
NLLAEHGB_01489 4.1e-201 yibE S YibE/F-like protein
NLLAEHGB_01490 4.2e-125 yibF S YibE/F-like protein
NLLAEHGB_01491 1.5e-123 yfkO C nitroreductase
NLLAEHGB_01492 2.6e-129 treR K transcriptional
NLLAEHGB_01493 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NLLAEHGB_01494 1.2e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NLLAEHGB_01495 1.5e-37 ydgB S Spore germination protein gerPA/gerPF
NLLAEHGB_01496 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
NLLAEHGB_01497 5.4e-77 cotP O Belongs to the small heat shock protein (HSP20) family
NLLAEHGB_01498 7.8e-64 yhdN S Domain of unknown function (DUF1992)
NLLAEHGB_01499 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NLLAEHGB_01500 2.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
NLLAEHGB_01501 8.7e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NLLAEHGB_01502 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
NLLAEHGB_01503 3.1e-50 yflH S Protein of unknown function (DUF3243)
NLLAEHGB_01504 9.1e-19 yflI
NLLAEHGB_01505 1.5e-14 yflJ S Protein of unknown function (DUF2639)
NLLAEHGB_01506 4.4e-123 yflK S protein conserved in bacteria
NLLAEHGB_01507 2.2e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NLLAEHGB_01508 2.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NLLAEHGB_01509 4.3e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NLLAEHGB_01510 3.8e-227 citM C Citrate transporter
NLLAEHGB_01511 7e-178 yflP S Tripartite tricarboxylate transporter family receptor
NLLAEHGB_01512 4.7e-120 citT T response regulator
NLLAEHGB_01513 2.7e-275 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NLLAEHGB_01514 3.2e-81 srtA 3.4.22.70 M Sortase family
NLLAEHGB_01515 0.0 M1-568 M cell wall anchor domain
NLLAEHGB_01516 2.5e-152 M1-574 T Transcriptional regulatory protein, C terminal
NLLAEHGB_01517 0.0 ywpD T PhoQ Sensor
NLLAEHGB_01518 8.6e-78 M1-820 Q Collagen triple helix repeat (20 copies)
NLLAEHGB_01520 9.3e-29 Q PFAM Collagen triple helix
NLLAEHGB_01521 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
NLLAEHGB_01522 1.7e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NLLAEHGB_01523 1.3e-57 yflT S Heat induced stress protein YflT
NLLAEHGB_01524 2.9e-24 S Protein of unknown function (DUF3212)
NLLAEHGB_01525 1.6e-188 yfmJ S N-terminal domain of oxidoreductase
NLLAEHGB_01526 5.4e-64 yfmK 2.3.1.128 K acetyltransferase
NLLAEHGB_01527 8.5e-207 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NLLAEHGB_01528 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NLLAEHGB_01529 2.1e-208 yfmO EGP Major facilitator Superfamily
NLLAEHGB_01530 1.8e-69 yfmP K transcriptional
NLLAEHGB_01531 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NLLAEHGB_01532 3.2e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NLLAEHGB_01533 5.2e-167 IQ Enoyl-(Acyl carrier protein) reductase
NLLAEHGB_01534 9.8e-115 yfmS NT chemotaxis protein
NLLAEHGB_01535 1.3e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NLLAEHGB_01536 3.9e-246 yfnA E amino acid
NLLAEHGB_01537 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
NLLAEHGB_01538 5.6e-188 yfnD M Nucleotide-diphospho-sugar transferase
NLLAEHGB_01539 7.8e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NLLAEHGB_01540 3.2e-180 yfnF M Nucleotide-diphospho-sugar transferase
NLLAEHGB_01541 2.4e-172 yfnG 4.2.1.45 M dehydratase
NLLAEHGB_01542 2.7e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
NLLAEHGB_01543 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NLLAEHGB_01545 1.9e-144 2.1.1.163, 2.1.1.201 Q methyltransferase
NLLAEHGB_01546 9.5e-113 S CAAX protease self-immunity
NLLAEHGB_01547 6.6e-153 sagB C Nitroreductase family
NLLAEHGB_01548 1e-267 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
NLLAEHGB_01549 6.7e-192 S ATP diphosphatase activity
NLLAEHGB_01550 6.4e-128
NLLAEHGB_01551 8.4e-75 S protein homooligomerization
NLLAEHGB_01552 1.3e-126 V ABC-2 type transporter
NLLAEHGB_01553 5.7e-166 V ATPases associated with a variety of cellular activities
NLLAEHGB_01554 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
NLLAEHGB_01556 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NLLAEHGB_01557 7.5e-197 yetN S Protein of unknown function (DUF3900)
NLLAEHGB_01558 1.7e-207 yetM CH FAD binding domain
NLLAEHGB_01559 2.5e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
NLLAEHGB_01560 1.1e-105 yetJ S Belongs to the BI1 family
NLLAEHGB_01561 1.3e-53 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
NLLAEHGB_01562 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
NLLAEHGB_01563 3.4e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NLLAEHGB_01564 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLLAEHGB_01565 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NLLAEHGB_01566 8.7e-122 yetF S membrane
NLLAEHGB_01568 4e-98 yesJ K Acetyltransferase (GNAT) family
NLLAEHGB_01569 8.9e-104 cotJC P Spore Coat
NLLAEHGB_01570 3.3e-45 cotJB S CotJB protein
NLLAEHGB_01571 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
NLLAEHGB_01572 2.4e-108 aadK G Streptomycin adenylyltransferase
NLLAEHGB_01574 9.4e-127 yeeN K transcriptional regulatory protein
NLLAEHGB_01575 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
NLLAEHGB_01576 4.8e-79 S Protein of unknown function, DUF600
NLLAEHGB_01577 2.8e-53 S Protein of unknown function, DUF600
NLLAEHGB_01578 5.6e-48 S Protein of unknown function, DUF600
NLLAEHGB_01579 1.6e-58 S Protein of unknown function, DUF600
NLLAEHGB_01580 1.6e-24 S Protein of unknown function, DUF600
NLLAEHGB_01581 2.2e-138 cylB V ABC-2 type transporter
NLLAEHGB_01582 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
NLLAEHGB_01583 8.5e-112 IQ reductase
NLLAEHGB_01584 3.7e-131 2.3.1.179 I 3-oxoacyl-[acyl-carrier-protein] synthase activity
NLLAEHGB_01585 2.8e-194 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NLLAEHGB_01586 4.5e-63 fabZ 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NLLAEHGB_01587 1.8e-33 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLLAEHGB_01589 1.6e-79 KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NLLAEHGB_01590 2.1e-247 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLLAEHGB_01591 2.1e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NLLAEHGB_01592 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NLLAEHGB_01593 1.5e-152 yerO K Transcriptional regulator
NLLAEHGB_01594 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLLAEHGB_01595 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NLLAEHGB_01596 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLLAEHGB_01597 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLLAEHGB_01598 4.3e-121 sapB S MgtC SapB transporter
NLLAEHGB_01599 6.1e-193 yerI S homoserine kinase type II (protein kinase fold)
NLLAEHGB_01600 2.3e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
NLLAEHGB_01601 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NLLAEHGB_01602 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NLLAEHGB_01603 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NLLAEHGB_01604 7.9e-304 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NLLAEHGB_01605 2.4e-50 yerC S protein conserved in bacteria
NLLAEHGB_01606 5.2e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
NLLAEHGB_01607 0.0 yerA 3.5.4.2 F adenine deaminase
NLLAEHGB_01608 1.2e-25 S Protein of unknown function (DUF2892)
NLLAEHGB_01609 7e-234 purD 6.3.4.13 F Belongs to the GARS family
NLLAEHGB_01610 7.8e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NLLAEHGB_01611 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NLLAEHGB_01612 7.8e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NLLAEHGB_01613 8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NLLAEHGB_01614 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLLAEHGB_01615 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLLAEHGB_01616 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLLAEHGB_01617 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NLLAEHGB_01618 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NLLAEHGB_01619 3.6e-224 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NLLAEHGB_01620 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NLLAEHGB_01621 6.1e-28 yebG S NETI protein
NLLAEHGB_01622 2e-92 yebE S UPF0316 protein
NLLAEHGB_01624 5.6e-133 yebC M Membrane
NLLAEHGB_01625 6.2e-209 pbuG S permease
NLLAEHGB_01626 2.1e-263 S Domain of unknown function (DUF4179)
NLLAEHGB_01627 3e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NLLAEHGB_01628 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NLLAEHGB_01629 0.0 yebA E COG1305 Transglutaminase-like enzymes
NLLAEHGB_01630 4.4e-214 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NLLAEHGB_01631 1.9e-175 yeaC S COG0714 MoxR-like ATPases
NLLAEHGB_01632 4.2e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLLAEHGB_01633 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NLLAEHGB_01634 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NLLAEHGB_01635 7.2e-35 ydjO S Cold-inducible protein YdjO
NLLAEHGB_01637 9.4e-136 ydjN U Involved in the tonB-independent uptake of proteins
NLLAEHGB_01638 1.4e-62 ydjM M Lytic transglycolase
NLLAEHGB_01639 2.3e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NLLAEHGB_01640 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NLLAEHGB_01641 8.6e-143 rsiV S Protein of unknown function (DUF3298)
NLLAEHGB_01642 0.0 yrhL I Acyltransferase family
NLLAEHGB_01643 3.1e-144 ydjI S virion core protein (lumpy skin disease virus)
NLLAEHGB_01644 3.3e-122 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NLLAEHGB_01645 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NLLAEHGB_01646 1.8e-114 pspA KT Phage shock protein A
NLLAEHGB_01647 4.7e-30 yjdJ S Domain of unknown function (DUF4306)
NLLAEHGB_01648 5.8e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NLLAEHGB_01649 7.1e-205 gutA G MFS/sugar transport protein
NLLAEHGB_01650 1.1e-200 gutB 1.1.1.14 E Dehydrogenase
NLLAEHGB_01651 0.0 K NB-ARC domain
NLLAEHGB_01652 2.2e-61
NLLAEHGB_01654 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NLLAEHGB_01655 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NLLAEHGB_01656 2.5e-127 ydiL S CAAX protease self-immunity
NLLAEHGB_01657 1.7e-27 ydiK S Domain of unknown function (DUF4305)
NLLAEHGB_01658 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NLLAEHGB_01659 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NLLAEHGB_01660 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NLLAEHGB_01661 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NLLAEHGB_01662 0.0 ydiF S ABC transporter
NLLAEHGB_01663 2.3e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NLLAEHGB_01664 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NLLAEHGB_01665 8.4e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NLLAEHGB_01666 1.2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NLLAEHGB_01667 3.9e-184 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NLLAEHGB_01669 7.8e-08
NLLAEHGB_01670 0.0 Q Polyketide synthase of type I
NLLAEHGB_01671 0.0 Q Polyketide synthase of type I
NLLAEHGB_01672 0.0 Q Polyketide synthase of type I
NLLAEHGB_01673 0.0 Q polyketide synthase
NLLAEHGB_01674 0.0 Q Polyketide synthase of type I
NLLAEHGB_01675 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NLLAEHGB_01676 5.8e-104 recN L Putative cell-wall binding lipoprotein
NLLAEHGB_01678 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NLLAEHGB_01679 4.7e-148 ykrA S hydrolases of the HAD superfamily
NLLAEHGB_01680 8.2e-31 ykzG S Belongs to the UPF0356 family
NLLAEHGB_01681 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLLAEHGB_01682 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NLLAEHGB_01683 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
NLLAEHGB_01684 1.1e-150 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NLLAEHGB_01685 6.3e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NLLAEHGB_01686 2.1e-45 abrB K of stationary sporulation gene expression
NLLAEHGB_01687 6.9e-184 mreB D Rod-share determining protein MreBH
NLLAEHGB_01688 7.2e-12 S Uncharacterized protein YkpC
NLLAEHGB_01689 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NLLAEHGB_01690 9.6e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLLAEHGB_01691 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NLLAEHGB_01692 1.2e-37 ykoA
NLLAEHGB_01693 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NLLAEHGB_01694 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NLLAEHGB_01695 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NLLAEHGB_01696 1.1e-133 fruR K Transcriptional regulator
NLLAEHGB_01697 6.4e-213 yknZ V ABC transporter (permease)
NLLAEHGB_01698 6.1e-123 macB V ABC transporter, ATP-binding protein
NLLAEHGB_01699 4e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NLLAEHGB_01700 1.4e-103 yknW S Yip1 domain
NLLAEHGB_01701 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NLLAEHGB_01702 7.1e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NLLAEHGB_01703 4.5e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NLLAEHGB_01704 2.9e-243 moeA 2.10.1.1 H molybdopterin
NLLAEHGB_01705 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NLLAEHGB_01706 1.4e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NLLAEHGB_01707 1.9e-162 yknT
NLLAEHGB_01708 1.5e-98 rok K Repressor of ComK
NLLAEHGB_01709 4.2e-80 ykuV CO thiol-disulfide
NLLAEHGB_01710 5.8e-141 ykuT M Mechanosensitive ion channel
NLLAEHGB_01711 4.8e-38 ykuS S Belongs to the UPF0180 family
NLLAEHGB_01712 2.6e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NLLAEHGB_01713 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NLLAEHGB_01714 2.5e-80 fld C Flavodoxin
NLLAEHGB_01715 2.9e-170 ykuO
NLLAEHGB_01716 3e-89 fld C Flavodoxin
NLLAEHGB_01717 6e-168 ccpC K Transcriptional regulator
NLLAEHGB_01718 1e-75 ykuL S CBS domain
NLLAEHGB_01719 2.5e-26 ykzF S Antirepressor AbbA
NLLAEHGB_01720 4.9e-93 ykuK S Ribonuclease H-like
NLLAEHGB_01721 3.9e-37 ykuJ S protein conserved in bacteria
NLLAEHGB_01722 1.5e-233 ykuI T Diguanylate phosphodiesterase
NLLAEHGB_01724 2.4e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NLLAEHGB_01725 6.1e-157 ykuE S Metallophosphoesterase
NLLAEHGB_01726 3.2e-89 ykuD S protein conserved in bacteria
NLLAEHGB_01727 7.8e-241 ykuC EGP Major facilitator Superfamily
NLLAEHGB_01728 1.4e-83 ykyB S YkyB-like protein
NLLAEHGB_01729 1.3e-97 S A nuclease of the HNH/ENDO VII superfamily with conserved WHH
NLLAEHGB_01730 4.3e-85 yokK S SMI1 / KNR4 family
NLLAEHGB_01731 1.2e-09 S Acetyltransferase (GNAT) domain
NLLAEHGB_01732 1.1e-24
NLLAEHGB_01733 1.1e-59 3.4.24.40 S amine dehydrogenase activity
NLLAEHGB_01735 2.6e-200 S aspartate phosphatase
NLLAEHGB_01736 2.8e-76 yoqH M LysM domain
NLLAEHGB_01741 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
NLLAEHGB_01742 1.2e-221 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NLLAEHGB_01743 5.2e-181 cgeB S Spore maturation protein
NLLAEHGB_01744 2.7e-52 cgeA
NLLAEHGB_01745 1e-42 cgeC
NLLAEHGB_01746 8e-246 cgeD M maturation of the outermost layer of the spore
NLLAEHGB_01747 3.5e-143 yiiD K acetyltransferase
NLLAEHGB_01749 4.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NLLAEHGB_01750 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NLLAEHGB_01751 6.1e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NLLAEHGB_01752 5.1e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
NLLAEHGB_01753 3.6e-157 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NLLAEHGB_01754 1.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
NLLAEHGB_01755 2.7e-45 yokU S YokU-like protein, putative antitoxin
NLLAEHGB_01756 4.1e-36 yozE S Belongs to the UPF0346 family
NLLAEHGB_01757 4.9e-125 yodN
NLLAEHGB_01759 6.2e-24 yozD S YozD-like protein
NLLAEHGB_01760 7.3e-104 yodM 3.6.1.27 I Acid phosphatase homologues
NLLAEHGB_01761 8.6e-56 yodL S YodL-like
NLLAEHGB_01763 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NLLAEHGB_01764 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NLLAEHGB_01765 4.3e-34 yodI
NLLAEHGB_01766 2.8e-128 yodH Q Methyltransferase
NLLAEHGB_01767 6.1e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NLLAEHGB_01768 5.2e-133 yydK K Transcriptional regulator
NLLAEHGB_01769 5.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLLAEHGB_01770 1.9e-283 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
NLLAEHGB_01771 1e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLLAEHGB_01772 1.4e-19 S Protein of unknown function (DUF3311)
NLLAEHGB_01773 1.2e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
NLLAEHGB_01774 6.1e-111 mhqD S Carboxylesterase
NLLAEHGB_01775 4.5e-106 yodC C nitroreductase
NLLAEHGB_01776 3e-56 yodB K transcriptional
NLLAEHGB_01777 7.5e-20 yoaQ S Evidence 4 Homologs of previously reported genes of
NLLAEHGB_01778 2e-67 yodA S tautomerase
NLLAEHGB_01780 2.3e-81 yozR S COG0071 Molecular chaperone (small heat shock protein)
NLLAEHGB_01781 3.5e-163 rarD S -transporter
NLLAEHGB_01782 6.4e-23
NLLAEHGB_01783 9.7e-61 yojF S Protein of unknown function (DUF1806)
NLLAEHGB_01784 2.5e-126 yojG S deacetylase
NLLAEHGB_01785 1.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NLLAEHGB_01786 5.7e-242 norM V Multidrug efflux pump
NLLAEHGB_01788 7.4e-112 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NLLAEHGB_01789 1.1e-225 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NLLAEHGB_01790 9.5e-228 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NLLAEHGB_01791 5.9e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NLLAEHGB_01792 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
NLLAEHGB_01793 0.0 yojO P Von Willebrand factor
NLLAEHGB_01794 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NLLAEHGB_01795 5.5e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NLLAEHGB_01796 2.6e-140 S Metallo-beta-lactamase superfamily
NLLAEHGB_01797 6e-161 yocS S -transporter
NLLAEHGB_01798 3e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NLLAEHGB_01799 3.2e-166 sodA 1.15.1.1 P Superoxide dismutase
NLLAEHGB_01800 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NLLAEHGB_01801 1.3e-287 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NLLAEHGB_01802 1.6e-31 yozC
NLLAEHGB_01804 2.4e-56 yozO S Bacterial PH domain
NLLAEHGB_01805 8.5e-37 yocN
NLLAEHGB_01806 3.8e-44 yozN
NLLAEHGB_01807 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
NLLAEHGB_01808 1.7e-08
NLLAEHGB_01809 7.8e-10 yocL
NLLAEHGB_01810 6.8e-60 dksA T general stress protein
NLLAEHGB_01812 2.8e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NLLAEHGB_01813 0.0 recQ 3.6.4.12 L DNA helicase
NLLAEHGB_01814 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
NLLAEHGB_01816 3.8e-187 yocD 3.4.17.13 V peptidase S66
NLLAEHGB_01817 1.9e-94 yocC
NLLAEHGB_01818 6.6e-142 yocB J Protein required for attachment to host cells
NLLAEHGB_01819 6.9e-90 yozB S membrane
NLLAEHGB_01820 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NLLAEHGB_01821 3.4e-55 czrA K transcriptional
NLLAEHGB_01822 4.2e-92 yobW
NLLAEHGB_01823 1.4e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NLLAEHGB_01824 7.5e-95 yobS K Transcriptional regulator
NLLAEHGB_01825 7.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
NLLAEHGB_01826 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NLLAEHGB_01827 4.8e-67 yxxG
NLLAEHGB_01829 2.2e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
NLLAEHGB_01830 3e-146 yxxF EG EamA-like transporter family
NLLAEHGB_01831 9.8e-74 yxiE T Belongs to the universal stress protein A family
NLLAEHGB_01832 2.7e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLLAEHGB_01833 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NLLAEHGB_01834 1.9e-17 L HNH nucleases
NLLAEHGB_01835 4.9e-37 P Cfr10I/Bse634I restriction endonuclease
NLLAEHGB_01837 3.8e-138 2.1.1.37 L C-5 cytosine-specific DNA methylase
NLLAEHGB_01838 8.4e-281 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NLLAEHGB_01839 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NLLAEHGB_01840 8.6e-287 hutH 4.3.1.3 E Histidine ammonia-lyase
NLLAEHGB_01841 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NLLAEHGB_01842 1.4e-237 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NLLAEHGB_01843 2.1e-174 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NLLAEHGB_01844 5.7e-253 lysP E amino acid
NLLAEHGB_01845 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NLLAEHGB_01846 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NLLAEHGB_01847 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NLLAEHGB_01848 3.3e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NLLAEHGB_01849 4e-150 yidA S hydrolases of the HAD superfamily
NLLAEHGB_01852 6.4e-13 yxeE
NLLAEHGB_01853 8.4e-23 yxeD
NLLAEHGB_01854 1.6e-32
NLLAEHGB_01855 3.9e-176 fhuD P Periplasmic binding protein
NLLAEHGB_01856 3.8e-57 yxeA S Protein of unknown function (DUF1093)
NLLAEHGB_01857 0.0 yxdM V ABC transporter (permease)
NLLAEHGB_01858 4.7e-140 yxdL V ABC transporter, ATP-binding protein
NLLAEHGB_01859 1.9e-175 T PhoQ Sensor
NLLAEHGB_01860 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLLAEHGB_01861 1.7e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NLLAEHGB_01862 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NLLAEHGB_01863 1.1e-166 iolH G Xylose isomerase-like TIM barrel
NLLAEHGB_01864 9.5e-197 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NLLAEHGB_01865 3.5e-233 iolF EGP Major facilitator Superfamily
NLLAEHGB_01866 1.1e-177 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NLLAEHGB_01867 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NLLAEHGB_01868 2.8e-182 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NLLAEHGB_01869 1.5e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NLLAEHGB_01870 1.5e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NLLAEHGB_01871 5.2e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
NLLAEHGB_01872 3.2e-175 iolS C Aldo keto reductase
NLLAEHGB_01873 1.5e-245 csbC EGP Major facilitator Superfamily
NLLAEHGB_01874 0.0 htpG O Molecular chaperone. Has ATPase activity
NLLAEHGB_01876 1.8e-150 IQ Enoyl-(Acyl carrier protein) reductase
NLLAEHGB_01877 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NLLAEHGB_01878 8.2e-202 desK 2.7.13.3 T Histidine kinase
NLLAEHGB_01879 2.2e-201 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NLLAEHGB_01880 2.9e-218 yxbF K Bacterial regulatory proteins, tetR family
NLLAEHGB_01881 3.3e-250 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NLLAEHGB_01882 4.4e-140 S PQQ-like domain
NLLAEHGB_01883 6e-65 S Family of unknown function (DUF5391)
NLLAEHGB_01884 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
NLLAEHGB_01885 1.4e-204 EGP Major facilitator Superfamily
NLLAEHGB_01886 1.5e-74 yxaI S membrane protein domain
NLLAEHGB_01887 1.6e-128 E Ring-cleavage extradiol dioxygenase
NLLAEHGB_01888 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NLLAEHGB_01889 2.3e-287 ahpF O Alkyl hydroperoxide reductase
NLLAEHGB_01890 3.8e-229 XK27_00240 S Fic/DOC family
NLLAEHGB_01891 6.5e-246 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
NLLAEHGB_01892 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NLLAEHGB_01893 1.1e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NLLAEHGB_01894 2.1e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NLLAEHGB_01895 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NLLAEHGB_01896 4.5e-93 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NLLAEHGB_01897 1.1e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NLLAEHGB_01898 5.6e-65 S Fusaric acid resistance protein-like
NLLAEHGB_01899 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NLLAEHGB_01900 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NLLAEHGB_01901 3.9e-78 argR K Regulates arginine biosynthesis genes
NLLAEHGB_01902 1.2e-305 recN L May be involved in recombinational repair of damaged DNA
NLLAEHGB_01903 1.4e-237 rseP 3.4.21.116 M Stage IV sporulation protein B
NLLAEHGB_01904 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NLLAEHGB_01905 6.1e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NLLAEHGB_01908 4.1e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NLLAEHGB_01910 1.8e-113 K Protein of unknown function (DUF1232)
NLLAEHGB_01911 1.5e-101 ytaF P Probably functions as a manganese efflux pump
NLLAEHGB_01912 2.5e-17
NLLAEHGB_01913 2.6e-104 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NLLAEHGB_01914 1.1e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NLLAEHGB_01915 2.8e-213 mmgA 2.3.1.9 I Belongs to the thiolase family
NLLAEHGB_01916 1.5e-155 hbdA 1.1.1.157 I Dehydrogenase
NLLAEHGB_01917 1.8e-204 mmgC I acyl-CoA dehydrogenase
NLLAEHGB_01918 5.7e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NLLAEHGB_01919 5.2e-278 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NLLAEHGB_01920 1.6e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NLLAEHGB_01921 3.2e-34 yqzF S Protein of unknown function (DUF2627)
NLLAEHGB_01922 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NLLAEHGB_01923 3.6e-152 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NLLAEHGB_01924 9.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NLLAEHGB_01925 4.4e-208 buk 2.7.2.7 C Belongs to the acetokinase family
NLLAEHGB_01926 2e-266 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NLLAEHGB_01927 8.6e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NLLAEHGB_01928 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NLLAEHGB_01929 8e-206 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NLLAEHGB_01930 1.2e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NLLAEHGB_01931 1e-75 yqiW S Belongs to the UPF0403 family
NLLAEHGB_01932 3.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
NLLAEHGB_01933 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
NLLAEHGB_01934 2.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NLLAEHGB_01935 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
NLLAEHGB_01936 1.1e-95 yqjB S protein conserved in bacteria
NLLAEHGB_01938 1.3e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NLLAEHGB_01939 1.3e-290 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NLLAEHGB_01940 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NLLAEHGB_01941 3.5e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLLAEHGB_01942 2.4e-25 yqzJ
NLLAEHGB_01943 3.9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLLAEHGB_01944 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NLLAEHGB_01945 2.5e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NLLAEHGB_01946 8.9e-170 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NLLAEHGB_01947 1e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NLLAEHGB_01948 2.8e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NLLAEHGB_01949 6.5e-24 S GlpM protein
NLLAEHGB_01950 4.9e-162 K LysR substrate binding domain
NLLAEHGB_01951 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
NLLAEHGB_01952 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NLLAEHGB_01955 8.3e-249 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NLLAEHGB_01956 2.1e-129 IQ reductase
NLLAEHGB_01957 2.4e-236 S Carbamoyl-phosphate synthase L chain, ATP binding domain
NLLAEHGB_01958 3.5e-244 M Glycosyltransferase Family 4
NLLAEHGB_01959 1.7e-122 S GlcNAc-PI de-N-acetylase
NLLAEHGB_01960 2.2e-122 KLT COG0515 Serine threonine protein kinase
NLLAEHGB_01961 4.9e-73 rplI J binds to the 23S rRNA
NLLAEHGB_01962 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NLLAEHGB_01963 1.6e-158 yybS S membrane
NLLAEHGB_01965 6.5e-85 cotF M Spore coat protein
NLLAEHGB_01966 2.8e-66 ydeP3 K Transcriptional regulator
NLLAEHGB_01967 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NLLAEHGB_01968 1.4e-165 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NLLAEHGB_01969 8.5e-273 sacB 2.4.1.10 GH68 M levansucrase activity
NLLAEHGB_01970 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
NLLAEHGB_01971 1.8e-116 K FCD domain
NLLAEHGB_01972 1.3e-77 dinB S PFAM DinB family protein
NLLAEHGB_01973 2e-161 G Major Facilitator Superfamily
NLLAEHGB_01974 8.7e-116 yfiE K LysR substrate binding domain
NLLAEHGB_01975 3.4e-25 yfiE K LysR substrate binding domain
NLLAEHGB_01976 1.1e-100 E LysE type translocator
NLLAEHGB_01977 8.3e-55 ypaA S Protein of unknown function (DUF1304)
NLLAEHGB_01978 5.6e-115 drgA C nitroreductase
NLLAEHGB_01979 3.2e-69 ydgJ K Winged helix DNA-binding domain
NLLAEHGB_01980 1.1e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NLLAEHGB_01981 7.3e-77 yybA 2.3.1.57 K transcriptional
NLLAEHGB_01982 7.7e-76 yjcF S Acetyltransferase (GNAT) domain
NLLAEHGB_01983 4.4e-163 eaeH M Domain of Unknown Function (DUF1259)
NLLAEHGB_01984 2.1e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
NLLAEHGB_01985 4.5e-166 K Transcriptional regulator
NLLAEHGB_01986 9.9e-138 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NLLAEHGB_01987 1.8e-249 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NLLAEHGB_01988 1.4e-130 ydfC EG EamA-like transporter family
NLLAEHGB_01989 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NLLAEHGB_01990 1.9e-161 yyaK S CAAX protease self-immunity
NLLAEHGB_01991 5.2e-248 ydjK G Sugar (and other) transporter
NLLAEHGB_01992 5.8e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLLAEHGB_01993 4.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NLLAEHGB_01994 1.6e-145 xth 3.1.11.2 L exodeoxyribonuclease III
NLLAEHGB_01995 1.8e-101 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NLLAEHGB_01996 3.9e-107 adaA 3.2.2.21 K Transcriptional regulator
NLLAEHGB_01997 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NLLAEHGB_01998 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NLLAEHGB_01999 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NLLAEHGB_02000 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NLLAEHGB_02001 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NLLAEHGB_02002 2.3e-33 yyzM S protein conserved in bacteria
NLLAEHGB_02003 2.4e-176 yyaD S Membrane
NLLAEHGB_02004 4.8e-85 4.2.1.103 K FR47-like protein
NLLAEHGB_02005 6.2e-111 yyaC S Sporulation protein YyaC
NLLAEHGB_02006 1.6e-149 spo0J K Belongs to the ParB family
NLLAEHGB_02007 9.2e-136 soj D COG1192 ATPases involved in chromosome partitioning
NLLAEHGB_02008 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NLLAEHGB_02009 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NLLAEHGB_02010 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NLLAEHGB_02011 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NLLAEHGB_02012 5.5e-110 jag S single-stranded nucleic acid binding R3H
NLLAEHGB_02013 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLLAEHGB_02014 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NLLAEHGB_02015 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NLLAEHGB_02016 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NLLAEHGB_02017 2.4e-33 yaaA S S4 domain
NLLAEHGB_02018 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NLLAEHGB_02019 8.1e-38 yaaB S Domain of unknown function (DUF370)
NLLAEHGB_02020 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLLAEHGB_02021 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLLAEHGB_02022 7.5e-77 ctsR K Belongs to the CtsR family
NLLAEHGB_02023 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NLLAEHGB_02024 1.6e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NLLAEHGB_02025 0.0 clpC O Belongs to the ClpA ClpB family
NLLAEHGB_02026 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NLLAEHGB_02027 6.4e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NLLAEHGB_02028 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NLLAEHGB_02029 7.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NLLAEHGB_02030 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NLLAEHGB_02031 8.1e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NLLAEHGB_02032 1e-116 cysE 2.3.1.30 E Serine acetyltransferase
NLLAEHGB_02033 6.2e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NLLAEHGB_02034 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NLLAEHGB_02035 3.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLLAEHGB_02036 4.2e-89 yacP S RNA-binding protein containing a PIN domain
NLLAEHGB_02037 8.9e-116 sigH K Belongs to the sigma-70 factor family
NLLAEHGB_02038 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NLLAEHGB_02039 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NLLAEHGB_02040 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NLLAEHGB_02041 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NLLAEHGB_02042 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NLLAEHGB_02043 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NLLAEHGB_02044 6.3e-108 rsmC 2.1.1.172 J Methyltransferase
NLLAEHGB_02045 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLLAEHGB_02046 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLLAEHGB_02047 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NLLAEHGB_02048 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NLLAEHGB_02049 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NLLAEHGB_02050 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NLLAEHGB_02051 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NLLAEHGB_02052 5.2e-189 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NLLAEHGB_02053 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NLLAEHGB_02054 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NLLAEHGB_02055 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
NLLAEHGB_02056 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NLLAEHGB_02057 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NLLAEHGB_02058 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NLLAEHGB_02059 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NLLAEHGB_02060 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NLLAEHGB_02061 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NLLAEHGB_02062 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NLLAEHGB_02063 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NLLAEHGB_02064 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NLLAEHGB_02065 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NLLAEHGB_02066 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NLLAEHGB_02067 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLLAEHGB_02068 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NLLAEHGB_02069 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NLLAEHGB_02070 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NLLAEHGB_02071 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NLLAEHGB_02072 1.9e-23 rpmD J Ribosomal protein L30
NLLAEHGB_02073 1.1e-72 rplO J binds to the 23S rRNA
NLLAEHGB_02074 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NLLAEHGB_02075 7.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NLLAEHGB_02076 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
NLLAEHGB_02077 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NLLAEHGB_02078 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NLLAEHGB_02079 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NLLAEHGB_02080 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NLLAEHGB_02081 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLLAEHGB_02082 4.7e-58 rplQ J Ribosomal protein L17
NLLAEHGB_02083 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLLAEHGB_02084 1.8e-148 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLLAEHGB_02085 1.2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLLAEHGB_02086 2.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NLLAEHGB_02087 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NLLAEHGB_02088 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NLLAEHGB_02089 8.2e-145 ybaJ Q Methyltransferase domain
NLLAEHGB_02090 4.2e-83 yizA S Damage-inducible protein DinB
NLLAEHGB_02091 4.5e-79 ybaK S Protein of unknown function (DUF2521)
NLLAEHGB_02092 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NLLAEHGB_02093 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NLLAEHGB_02094 7.6e-76 gerD
NLLAEHGB_02095 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NLLAEHGB_02096 1.4e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
NLLAEHGB_02097 2.2e-30 csfB S Inhibitor of sigma-G Gin
NLLAEHGB_02098 6e-98 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NLLAEHGB_02099 5.8e-192 yaaN P Belongs to the TelA family
NLLAEHGB_02100 2e-269 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NLLAEHGB_02101 3.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NLLAEHGB_02102 7.5e-55 yaaQ S protein conserved in bacteria
NLLAEHGB_02103 1.2e-71 yaaR S protein conserved in bacteria
NLLAEHGB_02104 1.3e-182 holB 2.7.7.7 L DNA polymerase III
NLLAEHGB_02105 8.8e-145 yaaT S stage 0 sporulation protein
NLLAEHGB_02106 7.7e-37 yabA L Involved in initiation control of chromosome replication
NLLAEHGB_02107 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NLLAEHGB_02108 4.7e-48 yazA L endonuclease containing a URI domain
NLLAEHGB_02109 3.4e-163 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NLLAEHGB_02110 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NLLAEHGB_02111 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLLAEHGB_02112 2.2e-142 tatD L hydrolase, TatD
NLLAEHGB_02113 1.8e-232 rpfB GH23 T protein conserved in bacteria
NLLAEHGB_02114 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NLLAEHGB_02115 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NLLAEHGB_02116 8.4e-146 yabG S peptidase
NLLAEHGB_02117 7.8e-39 veg S protein conserved in bacteria
NLLAEHGB_02118 2.9e-27 sspF S DNA topological change
NLLAEHGB_02119 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NLLAEHGB_02120 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NLLAEHGB_02121 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NLLAEHGB_02122 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NLLAEHGB_02123 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NLLAEHGB_02124 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLLAEHGB_02125 1.7e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NLLAEHGB_02126 9.4e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NLLAEHGB_02127 3.7e-40 yabK S Peptide ABC transporter permease
NLLAEHGB_02128 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NLLAEHGB_02129 6.2e-91 spoVT K stage V sporulation protein
NLLAEHGB_02130 9.2e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NLLAEHGB_02131 6.6e-276 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NLLAEHGB_02132 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NLLAEHGB_02133 1.9e-49 yabP S Sporulation protein YabP
NLLAEHGB_02134 5.8e-104 yabQ S spore cortex biosynthesis protein
NLLAEHGB_02135 4.1e-57 divIC D Septum formation initiator
NLLAEHGB_02136 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NLLAEHGB_02139 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NLLAEHGB_02140 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
NLLAEHGB_02141 1.4e-184 KLT serine threonine protein kinase
NLLAEHGB_02142 7.7e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NLLAEHGB_02143 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NLLAEHGB_02144 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NLLAEHGB_02145 4.8e-145 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NLLAEHGB_02146 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NLLAEHGB_02147 4.1e-156 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NLLAEHGB_02148 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NLLAEHGB_02149 6.1e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NLLAEHGB_02150 2.3e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NLLAEHGB_02151 1.9e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NLLAEHGB_02152 3.6e-157 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NLLAEHGB_02153 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NLLAEHGB_02154 1.9e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NLLAEHGB_02155 4.5e-29 yazB K transcriptional
NLLAEHGB_02156 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLLAEHGB_02157 9.3e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NLLAEHGB_02158 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NLLAEHGB_02159 2.1e-25
NLLAEHGB_02160 8.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NLLAEHGB_02161 6.9e-225 spoVID M stage VI sporulation protein D
NLLAEHGB_02162 6.2e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NLLAEHGB_02163 2.3e-184 hemB 4.2.1.24 H Belongs to the ALAD family
NLLAEHGB_02164 5e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NLLAEHGB_02165 3.9e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NLLAEHGB_02166 3.6e-146 hemX O cytochrome C
NLLAEHGB_02167 1.2e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NLLAEHGB_02168 1.3e-87 ysxD
NLLAEHGB_02169 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
NLLAEHGB_02170 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NLLAEHGB_02171 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NLLAEHGB_02172 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NLLAEHGB_02173 4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NLLAEHGB_02174 9.2e-189 ysoA H Tetratricopeptide repeat
NLLAEHGB_02175 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NLLAEHGB_02176 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NLLAEHGB_02177 4.8e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NLLAEHGB_02178 8.4e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NLLAEHGB_02179 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NLLAEHGB_02180 5.4e-84 ilvN 2.2.1.6 E Acetolactate synthase
NLLAEHGB_02181 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NLLAEHGB_02184 1.2e-193
NLLAEHGB_02185 1.2e-15 L COG1961 Site-specific recombinases, DNA invertase Pin homologs
NLLAEHGB_02186 1.5e-136 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
NLLAEHGB_02187 3.3e-248 hsdM 2.1.1.72 L type I restriction-modification system
NLLAEHGB_02188 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
NLLAEHGB_02189 3.1e-37 UW nuclease activity
NLLAEHGB_02190 3.8e-115 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NLLAEHGB_02191 2.6e-77 S SMI1-KNR4 cell-wall
NLLAEHGB_02192 1.1e-43
NLLAEHGB_02193 3e-99 hpr K helix_turn_helix multiple antibiotic resistance protein
NLLAEHGB_02195 7.5e-08 yoaF
NLLAEHGB_02196 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NLLAEHGB_02197 3.9e-195 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLLAEHGB_02198 5.9e-277 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
NLLAEHGB_02199 5.7e-204 yoaB EGP Major facilitator Superfamily
NLLAEHGB_02200 2.1e-140 yoxB
NLLAEHGB_02201 6.3e-40 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NLLAEHGB_02202 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NLLAEHGB_02203 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NLLAEHGB_02204 4.4e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLLAEHGB_02205 1.3e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NLLAEHGB_02206 8.7e-146 gltC K Transcriptional regulator
NLLAEHGB_02207 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NLLAEHGB_02208 1.7e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NLLAEHGB_02209 2.5e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NLLAEHGB_02210 6.8e-156 gltR1 K Transcriptional regulator
NLLAEHGB_02211 6.1e-15 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NLLAEHGB_02212 1.8e-50 ybzH K Helix-turn-helix domain
NLLAEHGB_02213 1.2e-200 ybcL EGP Major facilitator Superfamily
NLLAEHGB_02214 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NLLAEHGB_02215 1.8e-34 yoeD G Helix-turn-helix domain
NLLAEHGB_02216 2.2e-96 L Integrase
NLLAEHGB_02218 3.4e-97 yoeB S IseA DL-endopeptidase inhibitor
NLLAEHGB_02219 1e-246 yoeA V MATE efflux family protein
NLLAEHGB_02220 2.5e-183 yoxA 5.1.3.3 G Aldose 1-epimerase
NLLAEHGB_02221 1.5e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NLLAEHGB_02222 2.9e-243 M Glycosyltransferase Family 4
NLLAEHGB_02223 3.5e-17 yycC K YycC-like protein
NLLAEHGB_02225 8e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NLLAEHGB_02226 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NLLAEHGB_02227 4.8e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLLAEHGB_02228 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NLLAEHGB_02233 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLLAEHGB_02234 0.0 vicK 2.7.13.3 T Histidine kinase
NLLAEHGB_02235 1.4e-259 yycH S protein conserved in bacteria
NLLAEHGB_02236 1.4e-150 yycI S protein conserved in bacteria
NLLAEHGB_02237 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NLLAEHGB_02238 6e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NLLAEHGB_02239 4.7e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLLAEHGB_02240 6.8e-254 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
NLLAEHGB_02241 9.9e-191 2.7.7.73, 2.7.7.80 H ThiF family
NLLAEHGB_02242 1.1e-258
NLLAEHGB_02243 3.4e-198 S Major Facilitator Superfamily
NLLAEHGB_02244 3.3e-305 S ABC transporter
NLLAEHGB_02245 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
NLLAEHGB_02246 2.2e-260 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NLLAEHGB_02247 2.2e-42 sdpR K transcriptional
NLLAEHGB_02248 6.5e-63 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NLLAEHGB_02249 5.9e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NLLAEHGB_02250 2.2e-257 rocE E amino acid
NLLAEHGB_02251 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NLLAEHGB_02252 2.2e-199 S Histidine kinase
NLLAEHGB_02254 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
NLLAEHGB_02255 2.3e-184 C oxidoreductases (related to aryl-alcohol dehydrogenases)
NLLAEHGB_02256 8.3e-134 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NLLAEHGB_02257 6e-216 yycP
NLLAEHGB_02259 7.9e-08 S YyzF-like protein
NLLAEHGB_02261 4.3e-33
NLLAEHGB_02262 1e-78
NLLAEHGB_02264 2.6e-14 S YxiJ-like protein
NLLAEHGB_02265 3.9e-22
NLLAEHGB_02267 1.5e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NLLAEHGB_02268 2.9e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
NLLAEHGB_02269 2.6e-149 licT K transcriptional antiterminator
NLLAEHGB_02270 1.5e-143 exoK GH16 M licheninase activity
NLLAEHGB_02271 2.8e-222 citH C Citrate transporter
NLLAEHGB_02272 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NLLAEHGB_02273 1.4e-50 yxiS
NLLAEHGB_02274 7.8e-75 T Domain of unknown function (DUF4163)
NLLAEHGB_02275 3.8e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NLLAEHGB_02276 2.2e-162 rlmA 2.1.1.187 Q Methyltransferase domain
NLLAEHGB_02277 1.1e-217 yxjG 2.1.1.14 E Methionine synthase
NLLAEHGB_02278 1.2e-69 yxjI S LURP-one-related
NLLAEHGB_02281 4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NLLAEHGB_02282 1.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NLLAEHGB_02283 3.8e-87 yxkC S Domain of unknown function (DUF4352)
NLLAEHGB_02284 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NLLAEHGB_02285 3e-167 lrp QT PucR C-terminal helix-turn-helix domain
NLLAEHGB_02286 7.7e-205 msmK P Belongs to the ABC transporter superfamily
NLLAEHGB_02287 1.6e-157 yxkH G Polysaccharide deacetylase
NLLAEHGB_02288 4.1e-208 cimH C COG3493 Na citrate symporter
NLLAEHGB_02289 2.6e-266 cydA 1.10.3.14 C oxidase, subunit
NLLAEHGB_02290 7.4e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NLLAEHGB_02291 0.0 cydD V ATP-binding
NLLAEHGB_02292 2e-292 cydD V ATP-binding protein
NLLAEHGB_02293 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NLLAEHGB_02294 1.2e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NLLAEHGB_02295 7.2e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NLLAEHGB_02296 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NLLAEHGB_02297 4.4e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NLLAEHGB_02298 3.3e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
NLLAEHGB_02299 6e-168 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NLLAEHGB_02300 1.5e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLLAEHGB_02301 1.4e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLLAEHGB_02302 2e-49 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NLLAEHGB_02303 6.9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NLLAEHGB_02304 2.9e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NLLAEHGB_02305 9.1e-59 arsR K transcriptional
NLLAEHGB_02306 4e-167 cbrA3 P Periplasmic binding protein
NLLAEHGB_02307 1e-140 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLLAEHGB_02308 1.2e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLLAEHGB_02309 1.1e-109 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NLLAEHGB_02311 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NLLAEHGB_02312 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NLLAEHGB_02313 2.6e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLLAEHGB_02314 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NLLAEHGB_02315 1e-251 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NLLAEHGB_02316 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NLLAEHGB_02317 3.7e-229 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NLLAEHGB_02318 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_02319 1.4e-228 dltB M membrane protein involved in D-alanine export
NLLAEHGB_02320 3.9e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_02321 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
NLLAEHGB_02322 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NLLAEHGB_02323 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
NLLAEHGB_02324 1.1e-163 gspA M General stress
NLLAEHGB_02325 1.9e-266 epr 3.4.21.62 O Belongs to the peptidase S8 family
NLLAEHGB_02326 1.2e-244 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLLAEHGB_02327 7.6e-67 ywbC 4.4.1.5 E glyoxalase
NLLAEHGB_02328 6.1e-224 ywbD 2.1.1.191 J Methyltransferase
NLLAEHGB_02329 1.3e-170 yjfC O Predicted Zn-dependent protease (DUF2268)
NLLAEHGB_02330 2.2e-142 mta K transcriptional
NLLAEHGB_02331 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
NLLAEHGB_02333 1.3e-105
NLLAEHGB_02336 1e-95 V ATPases associated with a variety of cellular activities
NLLAEHGB_02337 1.3e-109 ywbG M effector of murein hydrolase
NLLAEHGB_02338 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NLLAEHGB_02339 8.2e-152 ywbI K Transcriptional regulator
NLLAEHGB_02340 2.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NLLAEHGB_02341 4.2e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NLLAEHGB_02342 8.1e-179 ywbN P Dyp-type peroxidase family protein
NLLAEHGB_02343 3.2e-52 ywbN P Dyp-type peroxidase family protein
NLLAEHGB_02344 5.5e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NLLAEHGB_02345 2.4e-132 S Streptomycin biosynthesis protein StrF
NLLAEHGB_02346 4.3e-129 H Methionine biosynthesis protein MetW
NLLAEHGB_02348 4.3e-112 ywcC K Bacterial regulatory proteins, tetR family
NLLAEHGB_02349 3.5e-62 gtcA S GtrA-like protein
NLLAEHGB_02350 8.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NLLAEHGB_02351 5.8e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NLLAEHGB_02352 8.4e-27 ywzA S membrane
NLLAEHGB_02353 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NLLAEHGB_02354 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NLLAEHGB_02355 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NLLAEHGB_02356 6.4e-63 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NLLAEHGB_02357 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
NLLAEHGB_02358 1.5e-78 ysnE K acetyltransferase
NLLAEHGB_02359 2.8e-208 rodA D Belongs to the SEDS family
NLLAEHGB_02360 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NLLAEHGB_02361 4e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLLAEHGB_02362 0.0 vpr O Belongs to the peptidase S8 family
NLLAEHGB_02364 8.3e-151 sacT K transcriptional antiterminator
NLLAEHGB_02365 2e-07 sacT K transcriptional antiterminator
NLLAEHGB_02366 4.7e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NLLAEHGB_02367 9.5e-288 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
NLLAEHGB_02368 9.7e-20 ywdA
NLLAEHGB_02369 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NLLAEHGB_02370 6.3e-57 pex K Transcriptional regulator PadR-like family
NLLAEHGB_02371 7.6e-88 ywdD
NLLAEHGB_02373 1.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
NLLAEHGB_02374 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NLLAEHGB_02375 4.7e-41 ywdI S Family of unknown function (DUF5327)
NLLAEHGB_02376 7.5e-231 ywdJ F Xanthine uracil
NLLAEHGB_02377 1.6e-45 ywdK S small membrane protein
NLLAEHGB_02378 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NLLAEHGB_02379 2.2e-142 spsA M Spore Coat
NLLAEHGB_02380 1.7e-276 spsB M Capsule polysaccharide biosynthesis protein
NLLAEHGB_02381 3.3e-222 spsC E Belongs to the DegT DnrJ EryC1 family
NLLAEHGB_02382 2e-160 spsD 2.3.1.210 K Spore Coat
NLLAEHGB_02383 3.4e-216 spsE 2.5.1.56 M acid synthase
NLLAEHGB_02384 1.6e-134 spsF M Spore Coat
NLLAEHGB_02385 1.8e-184 spsG M Spore Coat
NLLAEHGB_02386 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NLLAEHGB_02387 9.3e-183 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NLLAEHGB_02388 3.6e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NLLAEHGB_02389 3.5e-87 spsL 5.1.3.13 M Spore Coat
NLLAEHGB_02390 1.9e-172 bcrA5 V ABC transporter, ATP-binding protein
NLLAEHGB_02391 1.4e-119 S ABC-2 family transporter protein
NLLAEHGB_02392 8.5e-66
NLLAEHGB_02393 3.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLLAEHGB_02394 5.8e-161 T PhoQ Sensor
NLLAEHGB_02395 9.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NLLAEHGB_02396 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NLLAEHGB_02397 0.0 rocB E arginine degradation protein
NLLAEHGB_02398 1.1e-259 lysP E amino acid
NLLAEHGB_02399 9.9e-206 tcaB EGP Major facilitator Superfamily
NLLAEHGB_02400 2.4e-223 ywfA EGP Major facilitator Superfamily
NLLAEHGB_02401 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NLLAEHGB_02402 2.2e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NLLAEHGB_02403 1.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NLLAEHGB_02404 2.2e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NLLAEHGB_02405 4.7e-208 bacE EGP Major facilitator Superfamily
NLLAEHGB_02406 1.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
NLLAEHGB_02407 2.2e-140 IQ Enoyl-(Acyl carrier protein) reductase
NLLAEHGB_02408 1.1e-146 ywfI C May function as heme-dependent peroxidase
NLLAEHGB_02409 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NLLAEHGB_02410 1.3e-155 MA20_14895 S Conserved hypothetical protein 698
NLLAEHGB_02411 6e-163 cysL K Transcriptional regulator
NLLAEHGB_02412 2.9e-159 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NLLAEHGB_02414 6.1e-179
NLLAEHGB_02417 1.7e-168 yhcI S ABC transporter (permease)
NLLAEHGB_02418 9.1e-167 V ABC transporter, ATP-binding protein
NLLAEHGB_02419 5.2e-93 S membrane
NLLAEHGB_02420 4.1e-50 padR K PadR family transcriptional regulator
NLLAEHGB_02421 6.6e-110 rsfA_1
NLLAEHGB_02422 6.9e-36 ywzC S Belongs to the UPF0741 family
NLLAEHGB_02423 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
NLLAEHGB_02424 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
NLLAEHGB_02425 1.3e-246 yhdG_1 E C-terminus of AA_permease
NLLAEHGB_02426 8e-70 ywhA K Transcriptional regulator
NLLAEHGB_02427 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NLLAEHGB_02428 1.2e-117 ywhC S Peptidase family M50
NLLAEHGB_02429 1.4e-95 ywhD S YwhD family
NLLAEHGB_02430 8.5e-83
NLLAEHGB_02431 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NLLAEHGB_02432 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NLLAEHGB_02433 5.4e-169 speB 3.5.3.11 E Belongs to the arginase family
NLLAEHGB_02436 5.2e-76 CP Membrane
NLLAEHGB_02438 2e-28 S Domain of unknown function (DUF4177)
NLLAEHGB_02439 5e-33
NLLAEHGB_02440 2.6e-29 ydcG K sequence-specific DNA binding
NLLAEHGB_02442 1.4e-76 S aspartate phosphatase
NLLAEHGB_02443 3.8e-222 ywhK CO amine dehydrogenase activity
NLLAEHGB_02444 1.3e-230 ywhL CO amine dehydrogenase activity
NLLAEHGB_02445 1.2e-73 ywiB S protein conserved in bacteria
NLLAEHGB_02446 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NLLAEHGB_02447 5.8e-214 narK P COG2223 Nitrate nitrite transporter
NLLAEHGB_02448 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NLLAEHGB_02449 1.7e-139 ywiC S YwiC-like protein
NLLAEHGB_02450 2e-85 arfM T cyclic nucleotide binding
NLLAEHGB_02451 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NLLAEHGB_02452 5.3e-294 narH 1.7.5.1 C Nitrate reductase, beta
NLLAEHGB_02453 8.7e-96 narJ 1.7.5.1 C nitrate reductase
NLLAEHGB_02454 5.5e-121 narI 1.7.5.1 C nitrate reductase, gamma
NLLAEHGB_02455 1.4e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NLLAEHGB_02456 2.8e-301 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NLLAEHGB_02457 0.0 ywjA V ABC transporter
NLLAEHGB_02458 1.2e-42 ywjC
NLLAEHGB_02459 3.7e-179 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NLLAEHGB_02460 6e-219 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NLLAEHGB_02461 0.0 fadF C COG0247 Fe-S oxidoreductase
NLLAEHGB_02462 2.2e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NLLAEHGB_02463 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NLLAEHGB_02464 1.7e-93 ywjG S Domain of unknown function (DUF2529)
NLLAEHGB_02465 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
NLLAEHGB_02466 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NLLAEHGB_02467 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NLLAEHGB_02468 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLLAEHGB_02469 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NLLAEHGB_02470 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NLLAEHGB_02471 1.1e-32 rpmE J Binds the 23S rRNA
NLLAEHGB_02472 5.3e-104 tdk 2.7.1.21 F thymidine kinase
NLLAEHGB_02473 0.0 sfcA 1.1.1.38 C malic enzyme
NLLAEHGB_02474 3.6e-158 ywkB S Membrane transport protein
NLLAEHGB_02475 6.7e-96 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NLLAEHGB_02476 7.6e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLLAEHGB_02477 2.1e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NLLAEHGB_02478 1.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NLLAEHGB_02480 6.7e-60 ywlA S Uncharacterised protein family (UPF0715)
NLLAEHGB_02481 1.2e-110 spoIIR S stage II sporulation protein R
NLLAEHGB_02482 1.8e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NLLAEHGB_02483 9.6e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NLLAEHGB_02484 9e-85 mntP P Probably functions as a manganese efflux pump
NLLAEHGB_02485 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NLLAEHGB_02486 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NLLAEHGB_02487 2.2e-96 ywlG S Belongs to the UPF0340 family
NLLAEHGB_02488 2.5e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NLLAEHGB_02489 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NLLAEHGB_02490 2.1e-61 atpI S ATP synthase
NLLAEHGB_02491 9.3e-130 atpB C it plays a direct role in the translocation of protons across the membrane
NLLAEHGB_02492 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLLAEHGB_02493 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NLLAEHGB_02494 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLLAEHGB_02495 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NLLAEHGB_02496 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NLLAEHGB_02497 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NLLAEHGB_02498 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NLLAEHGB_02499 1.2e-90 ywmA
NLLAEHGB_02500 4.8e-32 ywzB S membrane
NLLAEHGB_02501 4.8e-134 ywmB S TATA-box binding
NLLAEHGB_02502 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLLAEHGB_02503 1.6e-188 spoIID D Stage II sporulation protein D
NLLAEHGB_02504 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NLLAEHGB_02505 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NLLAEHGB_02507 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NLLAEHGB_02508 1.8e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NLLAEHGB_02509 2.8e-93 S response regulator aspartate phosphatase
NLLAEHGB_02510 2.1e-82 ywmF S Peptidase M50
NLLAEHGB_02511 6.5e-11 csbD K CsbD-like
NLLAEHGB_02512 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NLLAEHGB_02513 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NLLAEHGB_02514 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NLLAEHGB_02515 6.1e-67 ywnA K Transcriptional regulator
NLLAEHGB_02516 4.5e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NLLAEHGB_02517 1.7e-53 ywnC S Family of unknown function (DUF5362)
NLLAEHGB_02518 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NLLAEHGB_02519 4.2e-69 ywnF S Family of unknown function (DUF5392)
NLLAEHGB_02520 1.2e-10 ywnC S Family of unknown function (DUF5362)
NLLAEHGB_02521 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NLLAEHGB_02522 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NLLAEHGB_02523 5.1e-72 ywnJ S VanZ like family
NLLAEHGB_02524 3.5e-100 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NLLAEHGB_02525 3.2e-209 ftsW D Belongs to the SEDS family
NLLAEHGB_02526 2e-58 nrgB K Belongs to the P(II) protein family
NLLAEHGB_02527 2.5e-228 amt P Ammonium transporter
NLLAEHGB_02528 3.7e-102 phzA Q Isochorismatase family
NLLAEHGB_02529 1.6e-244 ywoD EGP Major facilitator superfamily
NLLAEHGB_02530 1.4e-275 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NLLAEHGB_02531 4.9e-213 ywoG EGP Major facilitator Superfamily
NLLAEHGB_02532 8.5e-72 ywoH K transcriptional
NLLAEHGB_02533 1.8e-44 spoIIID K Stage III sporulation protein D
NLLAEHGB_02534 2.7e-180 mbl D Rod shape-determining protein
NLLAEHGB_02535 3.2e-128 flhO N flagellar basal body
NLLAEHGB_02536 4.4e-144 flhP N flagellar basal body
NLLAEHGB_02537 8.5e-201 S aspartate phosphatase
NLLAEHGB_02538 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NLLAEHGB_02539 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NLLAEHGB_02540 1.1e-68 ywpF S YwpF-like protein
NLLAEHGB_02541 4e-62 ywpG
NLLAEHGB_02542 1.3e-57 ssbB L Single-stranded DNA-binding protein
NLLAEHGB_02543 7.5e-138 glcR K DeoR C terminal sensor domain
NLLAEHGB_02544 2e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NLLAEHGB_02545 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NLLAEHGB_02546 2.1e-307 ywqB S SWIM zinc finger
NLLAEHGB_02547 1.3e-14
NLLAEHGB_02548 6.8e-112 ywqC M biosynthesis protein
NLLAEHGB_02549 6.7e-122 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NLLAEHGB_02550 1.6e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NLLAEHGB_02551 4.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NLLAEHGB_02552 2.3e-150 ywqG S Domain of unknown function (DUF1963)
NLLAEHGB_02554 1.1e-21 S Domain of unknown function (DUF5082)
NLLAEHGB_02555 4.3e-37 ywqI S Family of unknown function (DUF5344)
NLLAEHGB_02556 2e-260 ywqJ S Pre-toxin TG
NLLAEHGB_02557 7.7e-91
NLLAEHGB_02558 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_02559 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
NLLAEHGB_02560 4.1e-65 yngL S Protein of unknown function (DUF1360)
NLLAEHGB_02561 3.5e-304 yngK T Glycosyl hydrolase-like 10
NLLAEHGB_02562 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NLLAEHGB_02563 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NLLAEHGB_02564 1.2e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NLLAEHGB_02565 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NLLAEHGB_02566 2.5e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NLLAEHGB_02567 5.2e-139 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NLLAEHGB_02568 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NLLAEHGB_02569 3.5e-103 yngC S SNARE associated Golgi protein
NLLAEHGB_02570 2.2e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NLLAEHGB_02571 3.7e-72 yngA S membrane
NLLAEHGB_02572 6.3e-145 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NLLAEHGB_02573 4.6e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NLLAEHGB_02574 1.9e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NLLAEHGB_02575 4e-130 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NLLAEHGB_02576 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NLLAEHGB_02577 7.8e-227 bioI 1.14.14.46 C Cytochrome P450
NLLAEHGB_02578 4.5e-253 yxjC EG COG2610 H gluconate symporter and related permeases
NLLAEHGB_02579 1.1e-124 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NLLAEHGB_02580 7.1e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NLLAEHGB_02581 1.8e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NLLAEHGB_02582 7.6e-222 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NLLAEHGB_02585 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NLLAEHGB_02586 7.7e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NLLAEHGB_02587 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NLLAEHGB_02588 3.9e-225 ybbR S protein conserved in bacteria
NLLAEHGB_02589 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NLLAEHGB_02590 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NLLAEHGB_02591 4.7e-215 S Peptidase C14 caspase catalytic subunit p20
NLLAEHGB_02592 1.1e-26 CP_0264 3.2.2.10 S cytokinin biosynthetic process
NLLAEHGB_02593 6.2e-157 V ATPases associated with a variety of cellular activities
NLLAEHGB_02594 8.9e-108 S ABC-2 family transporter protein
NLLAEHGB_02595 7.8e-102 ybdN
NLLAEHGB_02596 2.9e-133 ybdO S Domain of unknown function (DUF4885)
NLLAEHGB_02597 1.5e-163 dkgB S Aldo/keto reductase family
NLLAEHGB_02598 1e-93 yxaC M effector of murein hydrolase
NLLAEHGB_02599 6.9e-52 S LrgA family
NLLAEHGB_02600 2.3e-72 yxaD K helix_turn_helix multiple antibiotic resistance protein
NLLAEHGB_02602 8.9e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NLLAEHGB_02604 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NLLAEHGB_02605 3.1e-86 ybbJ J acetyltransferase
NLLAEHGB_02606 8.9e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NLLAEHGB_02607 1.3e-238 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NLLAEHGB_02608 3.6e-246 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NLLAEHGB_02609 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NLLAEHGB_02610 1.7e-237 ybbC 3.2.1.52 S protein conserved in bacteria
NLLAEHGB_02611 2.2e-311 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NLLAEHGB_02612 1.7e-171 feuA P Iron-uptake system-binding protein
NLLAEHGB_02613 2.8e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLLAEHGB_02614 8e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLLAEHGB_02615 5.1e-115 ybbA S Putative esterase
NLLAEHGB_02616 3.7e-174 ybaS 1.1.1.58 S Na -dependent transporter
NLLAEHGB_02617 4.6e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NLLAEHGB_02618 2.6e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
NLLAEHGB_02619 5.7e-180 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
NLLAEHGB_02620 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NLLAEHGB_02621 8.4e-221 glcP G Major Facilitator Superfamily
NLLAEHGB_02622 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_02623 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NLLAEHGB_02624 2e-140 srfAD Q thioesterase
NLLAEHGB_02625 3e-248 bamJ E Aminotransferase class I and II
NLLAEHGB_02626 3.8e-64 S YcxB-like protein
NLLAEHGB_02627 6e-169 ycxC EG EamA-like transporter family
NLLAEHGB_02628 5.3e-245 ycxD K GntR family transcriptional regulator
NLLAEHGB_02629 3.8e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NLLAEHGB_02630 4.1e-110 yczE S membrane
NLLAEHGB_02631 1.5e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NLLAEHGB_02632 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
NLLAEHGB_02633 1.6e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NLLAEHGB_02634 1.1e-158 bsdA K LysR substrate binding domain
NLLAEHGB_02635 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NLLAEHGB_02636 5.9e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NLLAEHGB_02637 2e-38 bsdD 4.1.1.61 S response to toxic substance
NLLAEHGB_02638 2e-77 yclD
NLLAEHGB_02644 1.6e-08
NLLAEHGB_02648 1.7e-285 C Na+/H+ antiporter family
NLLAEHGB_02649 4.5e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NLLAEHGB_02650 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NLLAEHGB_02651 9e-264 ygaK C Berberine and berberine like
NLLAEHGB_02653 5.4e-229 oppA5 E PFAM extracellular solute-binding protein family 5
NLLAEHGB_02654 1.6e-137 appB P Binding-protein-dependent transport system inner membrane component
NLLAEHGB_02655 2.4e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLLAEHGB_02656 2.9e-134 oppD3 P Belongs to the ABC transporter superfamily
NLLAEHGB_02657 7.6e-132 oppF3 E Belongs to the ABC transporter superfamily
NLLAEHGB_02658 2.7e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NLLAEHGB_02659 5.8e-185 S Amidohydrolase
NLLAEHGB_02660 1.3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NLLAEHGB_02661 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
NLLAEHGB_02662 3.6e-32 yaaL S Protein of unknown function (DUF2508)
NLLAEHGB_02663 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NLLAEHGB_02664 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NLLAEHGB_02665 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLLAEHGB_02666 7.8e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NLLAEHGB_02667 2.2e-99 yaaI Q COG1335 Amidases related to nicotinamidase
NLLAEHGB_02668 3.8e-211 yaaH M Glycoside Hydrolase Family
NLLAEHGB_02669 4.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NLLAEHGB_02670 4.1e-121 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NLLAEHGB_02671 1.3e-09
NLLAEHGB_02672 2.9e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NLLAEHGB_02673 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NLLAEHGB_02674 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NLLAEHGB_02675 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NLLAEHGB_02676 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NLLAEHGB_02677 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NLLAEHGB_02678 1e-131 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NLLAEHGB_02679 1e-139 spoIIB S Sporulation related domain
NLLAEHGB_02680 1.2e-100 maf D septum formation protein Maf
NLLAEHGB_02681 1.8e-127 radC E Belongs to the UPF0758 family
NLLAEHGB_02682 4e-184 mreB D Rod shape-determining protein MreB
NLLAEHGB_02683 1.2e-157 mreC M Involved in formation and maintenance of cell shape
NLLAEHGB_02684 1.4e-84 mreD M shape-determining protein
NLLAEHGB_02685 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NLLAEHGB_02686 2.3e-142 minD D Belongs to the ParA family
NLLAEHGB_02687 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NLLAEHGB_02688 4.6e-160 spoIVFB S Stage IV sporulation protein
NLLAEHGB_02689 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
NLLAEHGB_02690 3.2e-56 ysxB J ribosomal protein
NLLAEHGB_02691 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NLLAEHGB_02692 8.7e-107 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NLLAEHGB_02693 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NLLAEHGB_02694 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NLLAEHGB_02695 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
NLLAEHGB_02696 2.1e-94 niaR S small molecule binding protein (contains 3H domain)
NLLAEHGB_02697 2.7e-224 nifS 2.8.1.7 E Cysteine desulfurase
NLLAEHGB_02698 0.0 Q Polyketide synthase of type I
NLLAEHGB_02699 0.0 1.1.1.320 Q Polyketide synthase of type I
NLLAEHGB_02700 0.0 pksJ Q Polyketide synthase of type I
NLLAEHGB_02701 8.4e-44 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_02702 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_02703 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_02706 4.3e-07
NLLAEHGB_02711 4.7e-21 K Cro/C1-type HTH DNA-binding domain
NLLAEHGB_02713 2.5e-23 K Helix-turn-helix domain
NLLAEHGB_02715 2.2e-43
NLLAEHGB_02716 1.9e-23
NLLAEHGB_02717 4.1e-182 I Pfam Lipase (class 3)
NLLAEHGB_02718 5.1e-28 S Protein of unknown function (DUF1433)
NLLAEHGB_02720 2.1e-160 S aspartate phosphatase
NLLAEHGB_02721 1.9e-22
NLLAEHGB_02722 8.3e-07
NLLAEHGB_02723 4.4e-68 yvrL S Regulatory protein YrvL
NLLAEHGB_02724 2.1e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
NLLAEHGB_02725 1.6e-15 S YvrJ protein family
NLLAEHGB_02726 9.9e-103 yvrI K RNA polymerase
NLLAEHGB_02727 5.6e-36
NLLAEHGB_02728 1.5e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLLAEHGB_02729 0.0 T PhoQ Sensor
NLLAEHGB_02730 5.8e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NLLAEHGB_02731 5.3e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NLLAEHGB_02732 1.1e-167 yvrC P ABC transporter substrate-binding protein
NLLAEHGB_02733 9.6e-181 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLLAEHGB_02734 9.8e-225 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NLLAEHGB_02735 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
NLLAEHGB_02736 5.2e-229 yvqJ EGP Major facilitator Superfamily
NLLAEHGB_02737 3.3e-46 liaI S membrane
NLLAEHGB_02738 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NLLAEHGB_02739 7.6e-115 liaG S Putative adhesin
NLLAEHGB_02740 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NLLAEHGB_02741 2.3e-193 vraS 2.7.13.3 T Histidine kinase
NLLAEHGB_02742 9.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NLLAEHGB_02743 7.3e-211 gerAC S Spore germination B3/ GerAC like, C-terminal
NLLAEHGB_02744 5e-188 gerAB E Spore germination protein
NLLAEHGB_02745 2.2e-260 gerAA EG Spore germination protein
NLLAEHGB_02746 6.6e-24 S Protein of unknown function (DUF3970)
NLLAEHGB_02747 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NLLAEHGB_02748 8.5e-157 yuxN K Transcriptional regulator
NLLAEHGB_02749 3.4e-24
NLLAEHGB_02750 2.3e-251 cssS 2.7.13.3 T PhoQ Sensor
NLLAEHGB_02751 7.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLLAEHGB_02752 2.7e-239 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NLLAEHGB_02753 1.6e-79 dps P Belongs to the Dps family
NLLAEHGB_02754 9.6e-155 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NLLAEHGB_02755 0.0 pepF2 E COG1164 Oligoendopeptidase F
NLLAEHGB_02756 7.2e-45 S YusW-like protein
NLLAEHGB_02757 1.4e-150 yusV 3.6.3.34 HP ABC transporter
NLLAEHGB_02758 3.3e-39 yusU S Protein of unknown function (DUF2573)
NLLAEHGB_02759 3.9e-190 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLLAEHGB_02760 4.1e-141 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
NLLAEHGB_02761 3.9e-159 ywbI2 K Transcriptional regulator
NLLAEHGB_02762 8.1e-288 yusP P Major facilitator superfamily
NLLAEHGB_02763 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
NLLAEHGB_02764 1.1e-53 yusN M Coat F domain
NLLAEHGB_02765 3.9e-43
NLLAEHGB_02766 8.4e-165 fadM E Proline dehydrogenase
NLLAEHGB_02767 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NLLAEHGB_02768 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
NLLAEHGB_02769 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NLLAEHGB_02770 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NLLAEHGB_02771 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NLLAEHGB_02772 3.7e-40 yusG S Protein of unknown function (DUF2553)
NLLAEHGB_02773 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NLLAEHGB_02774 1.6e-54 yusE CO Thioredoxin
NLLAEHGB_02775 5e-57 yusD S SCP-2 sterol transfer family
NLLAEHGB_02776 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NLLAEHGB_02777 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NLLAEHGB_02778 2.3e-145 metQ P Belongs to the NlpA lipoprotein family
NLLAEHGB_02779 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NLLAEHGB_02780 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NLLAEHGB_02781 1.2e-244 sufD O assembly protein SufD
NLLAEHGB_02782 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NLLAEHGB_02783 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NLLAEHGB_02784 3e-270 sufB O FeS cluster assembly
NLLAEHGB_02785 6.6e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NLLAEHGB_02786 4.2e-80 yncE S Protein of unknown function (DUF2691)
NLLAEHGB_02787 2e-126 Q ubiE/COQ5 methyltransferase family
NLLAEHGB_02788 2.1e-202 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NLLAEHGB_02789 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NLLAEHGB_02792 1e-165 K helix_turn_helix, mercury resistance
NLLAEHGB_02793 1.1e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NLLAEHGB_02794 1.1e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NLLAEHGB_02795 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
NLLAEHGB_02796 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
NLLAEHGB_02797 1.4e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NLLAEHGB_02798 3.1e-133 yurK K UTRA
NLLAEHGB_02799 1.7e-207 msmX P Belongs to the ABC transporter superfamily
NLLAEHGB_02800 4.1e-169 bsn L Ribonuclease
NLLAEHGB_02801 1.8e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NLLAEHGB_02802 1.3e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NLLAEHGB_02803 1.9e-212 blt EGP Major facilitator Superfamily
NLLAEHGB_02804 1.6e-47
NLLAEHGB_02805 2.3e-303 pucR QT COG2508 Regulator of polyketide synthase expression
NLLAEHGB_02806 1.7e-265 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NLLAEHGB_02807 1.5e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
NLLAEHGB_02808 2.6e-168 yunF S Protein of unknown function DUF72
NLLAEHGB_02809 1.8e-145 yunE S membrane transporter protein
NLLAEHGB_02810 2.8e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NLLAEHGB_02811 5.6e-130 yunB S Sporulation protein YunB (Spo_YunB)
NLLAEHGB_02812 4.2e-194 lytH M Peptidase, M23
NLLAEHGB_02813 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NLLAEHGB_02814 6.3e-47 yutD S protein conserved in bacteria
NLLAEHGB_02815 2.8e-73 yutE S Protein of unknown function DUF86
NLLAEHGB_02816 8.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NLLAEHGB_02817 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NLLAEHGB_02818 4.2e-197 yutH S Spore coat protein
NLLAEHGB_02819 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
NLLAEHGB_02820 4e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NLLAEHGB_02821 1.2e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NLLAEHGB_02822 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NLLAEHGB_02823 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NLLAEHGB_02824 3.3e-55 yuzD S protein conserved in bacteria
NLLAEHGB_02825 1.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
NLLAEHGB_02826 2.4e-39 yuzB S Belongs to the UPF0349 family
NLLAEHGB_02827 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NLLAEHGB_02828 5.7e-163 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NLLAEHGB_02829 1.1e-62 erpA S Belongs to the HesB IscA family
NLLAEHGB_02830 7.3e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NLLAEHGB_02831 2.2e-91 rimJ 2.3.1.128 J Alanine acetyltransferase
NLLAEHGB_02833 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
NLLAEHGB_02835 3.3e-124 V ABC transporter
NLLAEHGB_02836 3.1e-71 CP Membrane
NLLAEHGB_02837 4.8e-29
NLLAEHGB_02838 4.2e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NLLAEHGB_02840 1.1e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
NLLAEHGB_02841 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
NLLAEHGB_02842 9.9e-28 yuiB S Putative membrane protein
NLLAEHGB_02843 4.2e-118 yuiC S protein conserved in bacteria
NLLAEHGB_02844 3.5e-77 yuiD S protein conserved in bacteria
NLLAEHGB_02845 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NLLAEHGB_02846 4.5e-207 yuiF S antiporter
NLLAEHGB_02847 1.1e-101 bioY S Biotin biosynthesis protein
NLLAEHGB_02848 9.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
NLLAEHGB_02849 1.5e-166 besA S Putative esterase
NLLAEHGB_02850 4.6e-135 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NLLAEHGB_02851 9.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
NLLAEHGB_02852 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NLLAEHGB_02853 4.5e-174 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NLLAEHGB_02854 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_02855 1.3e-34 mbtH S MbtH-like protein
NLLAEHGB_02856 7.5e-134 yukJ S Uncharacterized conserved protein (DUF2278)
NLLAEHGB_02857 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NLLAEHGB_02858 1.5e-228 yukF QT Transcriptional regulator
NLLAEHGB_02859 3.3e-46 esxA S Belongs to the WXG100 family
NLLAEHGB_02860 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
NLLAEHGB_02861 2.8e-206 essB S WXG100 protein secretion system (Wss), protein YukC
NLLAEHGB_02862 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NLLAEHGB_02863 0.0 esaA S type VII secretion protein EsaA
NLLAEHGB_02864 3.8e-76 yueC S Family of unknown function (DUF5383)
NLLAEHGB_02865 3e-128 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NLLAEHGB_02866 6.3e-96 yueE S phosphohydrolase
NLLAEHGB_02867 1.6e-22 S Protein of unknown function (DUF2642)
NLLAEHGB_02868 1.9e-187 yueF S transporter activity
NLLAEHGB_02869 1.6e-32 yueG S Spore germination protein gerPA/gerPF
NLLAEHGB_02870 2.8e-38 yueH S YueH-like protein
NLLAEHGB_02871 2.7e-67 yueI S Protein of unknown function (DUF1694)
NLLAEHGB_02872 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
NLLAEHGB_02873 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NLLAEHGB_02874 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NLLAEHGB_02875 8.9e-51 yuzC
NLLAEHGB_02877 3.1e-66 comQ H Polyprenyl synthetase
NLLAEHGB_02879 3.9e-246 comP 2.7.13.3 T Histidine kinase
NLLAEHGB_02880 1.5e-112 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NLLAEHGB_02881 2.1e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
NLLAEHGB_02882 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NLLAEHGB_02883 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NLLAEHGB_02884 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NLLAEHGB_02885 2.6e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NLLAEHGB_02886 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NLLAEHGB_02887 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NLLAEHGB_02888 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NLLAEHGB_02889 1.8e-12
NLLAEHGB_02890 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
NLLAEHGB_02891 7.9e-183 yufP S Belongs to the binding-protein-dependent transport system permease family
NLLAEHGB_02892 7.3e-286 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NLLAEHGB_02893 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NLLAEHGB_02894 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
NLLAEHGB_02895 1.5e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NLLAEHGB_02896 9.3e-74 yufK S Family of unknown function (DUF5366)
NLLAEHGB_02897 8.5e-72 yuxK S protein conserved in bacteria
NLLAEHGB_02898 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NLLAEHGB_02899 1.5e-185 yuxJ EGP Major facilitator Superfamily
NLLAEHGB_02900 4.5e-118 kapD L the KinA pathway to sporulation
NLLAEHGB_02901 5.9e-67 kapB G Kinase associated protein B
NLLAEHGB_02902 3.6e-230 T PhoQ Sensor
NLLAEHGB_02903 6e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NLLAEHGB_02904 1.4e-40 yugE S Domain of unknown function (DUF1871)
NLLAEHGB_02905 1.1e-155 yugF I Hydrolase
NLLAEHGB_02906 2e-83 alaR K Transcriptional regulator
NLLAEHGB_02907 5e-210 yugH 2.6.1.1 E Aminotransferase
NLLAEHGB_02908 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NLLAEHGB_02909 1.8e-34 yuzA S Domain of unknown function (DUF378)
NLLAEHGB_02910 3.8e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NLLAEHGB_02911 7.4e-230 yugK C Dehydrogenase
NLLAEHGB_02912 5.5e-118 ycaC Q Isochorismatase family
NLLAEHGB_02913 2e-95 S NADPH-dependent FMN reductase
NLLAEHGB_02914 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
NLLAEHGB_02916 7e-71 yugN S YugN-like family
NLLAEHGB_02917 5.3e-181 yugO P COG1226 Kef-type K transport systems
NLLAEHGB_02918 9.6e-26 mstX S Membrane-integrating protein Mistic
NLLAEHGB_02919 4.5e-18
NLLAEHGB_02920 8.3e-117 yugP S Zn-dependent protease
NLLAEHGB_02921 8.7e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NLLAEHGB_02922 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NLLAEHGB_02923 6.8e-77 yugU S Uncharacterised protein family UPF0047
NLLAEHGB_02924 1.7e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NLLAEHGB_02925 4.8e-41
NLLAEHGB_02926 1.3e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NLLAEHGB_02927 4.9e-218 mcpA NT chemotaxis protein
NLLAEHGB_02928 8.6e-239 mcpA NT chemotaxis protein
NLLAEHGB_02929 3.2e-225 mcpA NT chemotaxis protein
NLLAEHGB_02930 1.9e-238 mcpA NT chemotaxis protein
NLLAEHGB_02931 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NLLAEHGB_02932 4.7e-185 ygjR S Oxidoreductase
NLLAEHGB_02933 9e-196 yubA S transporter activity
NLLAEHGB_02934 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NLLAEHGB_02936 4.5e-07
NLLAEHGB_02938 1.3e-124 G Cupin
NLLAEHGB_02939 2.9e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NLLAEHGB_02940 1.4e-145 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NLLAEHGB_02941 2.1e-120 ktrA P COG0569 K transport systems, NAD-binding component
NLLAEHGB_02942 2.1e-94 yuaB
NLLAEHGB_02943 2.7e-97 yuaC K Belongs to the GbsR family
NLLAEHGB_02944 5.5e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NLLAEHGB_02945 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
NLLAEHGB_02946 2.5e-109 yuaD S MOSC domain
NLLAEHGB_02947 3.6e-59 bacT Q Thioesterase domain
NLLAEHGB_02948 4.4e-14
NLLAEHGB_02949 6e-123 V ABC-2 type transporter
NLLAEHGB_02950 3.1e-146 V ABC-2 type transporter
NLLAEHGB_02951 3.5e-134 V ABC transporter, ATP-binding protein
NLLAEHGB_02952 4.9e-82 KT helix_turn_helix, Lux Regulon
NLLAEHGB_02953 1.8e-103 T Histidine kinase
NLLAEHGB_02954 2.5e-71 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_02955 3.1e-83 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_02956 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_02957 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLAEHGB_02958 4.7e-50 E Saccharopine dehydrogenase
NLLAEHGB_02959 5.3e-99 V ABC transporter transmembrane region
NLLAEHGB_02960 7.3e-256 Q Non-ribosomal peptide synthetase modules and related proteins
NLLAEHGB_02961 4.5e-52 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NLLAEHGB_02962 1.4e-158 3.6.4.12 L UvrD-like helicase C-terminal domain
NLLAEHGB_02963 2.3e-53 S Domain of unknown function (DUF4433)
NLLAEHGB_02964 2e-105 O ADP-ribosylglycohydrolase
NLLAEHGB_02965 2.6e-52 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NLLAEHGB_02966 1.8e-131 S AIPR protein
NLLAEHGB_02967 1.2e-17
NLLAEHGB_02968 1.7e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NLLAEHGB_02969 1.3e-259
NLLAEHGB_02970 1.1e-183 purR7 5.1.1.1 K Transcriptional regulator
NLLAEHGB_02972 6.6e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NLLAEHGB_02973 1.7e-178 yuaG 3.4.21.72 S protein conserved in bacteria
NLLAEHGB_02974 3.3e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
NLLAEHGB_02976 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLLAEHGB_02977 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLLAEHGB_02978 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NLLAEHGB_02979 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NLLAEHGB_02980 8.1e-67 yqhY S protein conserved in bacteria
NLLAEHGB_02981 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NLLAEHGB_02982 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NLLAEHGB_02983 2.5e-62 spoIIIAH S SpoIIIAH-like protein
NLLAEHGB_02984 2.2e-117 spoIIIAG S stage III sporulation protein AG
NLLAEHGB_02985 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NLLAEHGB_02986 6.3e-200 spoIIIAE S stage III sporulation protein AE
NLLAEHGB_02987 2.5e-41 spoIIIAD S Stage III sporulation protein AD
NLLAEHGB_02988 7.6e-29 spoIIIAC S stage III sporulation protein AC
NLLAEHGB_02989 1.7e-85 spoIIIAB S Stage III sporulation protein
NLLAEHGB_02990 4.2e-172 spoIIIAA S stage III sporulation protein AA
NLLAEHGB_02991 1.8e-36 yqhV S Protein of unknown function (DUF2619)
NLLAEHGB_02992 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NLLAEHGB_02993 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NLLAEHGB_02994 3.7e-88 yqhR S Conserved membrane protein YqhR
NLLAEHGB_02995 1.2e-172 yqhQ S Protein of unknown function (DUF1385)
NLLAEHGB_02996 3.4e-62 yqhP
NLLAEHGB_02997 9e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
NLLAEHGB_02998 6.1e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NLLAEHGB_02999 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NLLAEHGB_03000 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
NLLAEHGB_03001 4.1e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NLLAEHGB_03002 5.1e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NLLAEHGB_03003 2e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NLLAEHGB_03004 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NLLAEHGB_03005 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
NLLAEHGB_03006 5.2e-23 sinI S Anti-repressor SinI
NLLAEHGB_03007 7.8e-55 sinR K transcriptional
NLLAEHGB_03008 3.3e-141 tasA S Cell division protein FtsN
NLLAEHGB_03009 1.3e-70 sipW 3.4.21.89 U Signal peptidase
NLLAEHGB_03010 8.5e-122 yqxM
NLLAEHGB_03011 1.4e-53 yqzG S Protein of unknown function (DUF3889)
NLLAEHGB_03012 2.3e-26 yqzE S YqzE-like protein
NLLAEHGB_03013 1.2e-61 S ComG operon protein 7
NLLAEHGB_03014 1.6e-67 comGF U Putative Competence protein ComGF
NLLAEHGB_03015 7.6e-20 comGE
NLLAEHGB_03016 1.6e-73 gspH NU Tfp pilus assembly protein FimT
NLLAEHGB_03017 8.9e-50 comGC U Required for transformation and DNA binding
NLLAEHGB_03018 2.9e-185 comGB NU COG1459 Type II secretory pathway, component PulF
NLLAEHGB_03019 7.8e-202 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NLLAEHGB_03020 2.6e-185 corA P Mg2 transporter protein
NLLAEHGB_03021 3.3e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NLLAEHGB_03022 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NLLAEHGB_03024 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
NLLAEHGB_03025 3.1e-37 yqgY S Protein of unknown function (DUF2626)
NLLAEHGB_03026 8.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NLLAEHGB_03027 5.4e-20 yqgW S Protein of unknown function (DUF2759)
NLLAEHGB_03028 6.9e-50 yqgV S Thiamine-binding protein
NLLAEHGB_03029 3e-198 yqgU
NLLAEHGB_03030 2.7e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NLLAEHGB_03031 2.2e-179 glcK 2.7.1.2 G Glucokinase
NLLAEHGB_03032 1e-28 yqgQ S Protein conserved in bacteria
NLLAEHGB_03033 5e-230 nhaC C Na H antiporter
NLLAEHGB_03034 4e-07 yqgO
NLLAEHGB_03035 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NLLAEHGB_03036 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NLLAEHGB_03037 1.2e-50 yqzD
NLLAEHGB_03038 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NLLAEHGB_03039 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NLLAEHGB_03040 5.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NLLAEHGB_03041 1.4e-156 pstA P Phosphate transport system permease
NLLAEHGB_03042 1.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NLLAEHGB_03043 1.7e-157 pstS P Phosphate
NLLAEHGB_03044 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NLLAEHGB_03045 2e-228 yqgE EGP Major facilitator superfamily
NLLAEHGB_03046 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NLLAEHGB_03047 6e-77 yqgC S protein conserved in bacteria
NLLAEHGB_03048 8.7e-131 yqgB S Protein of unknown function (DUF1189)
NLLAEHGB_03049 3.7e-48 yqfZ M LysM domain
NLLAEHGB_03050 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NLLAEHGB_03051 2.3e-52 yqfX S membrane
NLLAEHGB_03052 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NLLAEHGB_03053 2.9e-72 zur P Belongs to the Fur family
NLLAEHGB_03054 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NLLAEHGB_03055 9.3e-37 yqfT S Protein of unknown function (DUF2624)
NLLAEHGB_03056 2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NLLAEHGB_03057 1.2e-247 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NLLAEHGB_03058 3.5e-49 yqfQ S YqfQ-like protein
NLLAEHGB_03059 1.7e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NLLAEHGB_03060 4.3e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NLLAEHGB_03061 4.1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
NLLAEHGB_03062 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
NLLAEHGB_03063 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NLLAEHGB_03064 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NLLAEHGB_03065 6.1e-88 yaiI S Belongs to the UPF0178 family
NLLAEHGB_03066 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NLLAEHGB_03067 4.5e-112 ccpN K CBS domain
NLLAEHGB_03068 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NLLAEHGB_03069 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NLLAEHGB_03070 7.6e-143 recO L Involved in DNA repair and RecF pathway recombination
NLLAEHGB_03071 1.8e-16 S YqzL-like protein
NLLAEHGB_03072 5.2e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NLLAEHGB_03073 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NLLAEHGB_03074 4.6e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NLLAEHGB_03075 2.5e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NLLAEHGB_03076 0.0 yqfF S membrane-associated HD superfamily hydrolase
NLLAEHGB_03077 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
NLLAEHGB_03078 1.8e-215 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NLLAEHGB_03079 9.3e-46 yqfC S sporulation protein YqfC
NLLAEHGB_03080 1.7e-54 yqfB
NLLAEHGB_03081 1.6e-121 yqfA S UPF0365 protein
NLLAEHGB_03082 4.4e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NLLAEHGB_03083 3.6e-68 yqeY S Yqey-like protein
NLLAEHGB_03084 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NLLAEHGB_03085 1.6e-158 yqeW P COG1283 Na phosphate symporter
NLLAEHGB_03086 1.2e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NLLAEHGB_03087 5.1e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NLLAEHGB_03088 1.6e-174 prmA J Methylates ribosomal protein L11
NLLAEHGB_03089 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NLLAEHGB_03090 0.0 dnaK O Heat shock 70 kDa protein
NLLAEHGB_03091 5.1e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NLLAEHGB_03092 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NLLAEHGB_03093 8.2e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
NLLAEHGB_03094 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NLLAEHGB_03095 1.5e-53 yqxA S Protein of unknown function (DUF3679)
NLLAEHGB_03096 1.4e-220 spoIIP M stage II sporulation protein P
NLLAEHGB_03097 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NLLAEHGB_03098 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
NLLAEHGB_03099 2.5e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
NLLAEHGB_03100 0.0 comEC S Competence protein ComEC
NLLAEHGB_03101 1e-104 comEB 3.5.4.12 F ComE operon protein 2
NLLAEHGB_03102 1.2e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
NLLAEHGB_03103 2.2e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLLAEHGB_03104 1.1e-138 yqeM Q Methyltransferase
NLLAEHGB_03105 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NLLAEHGB_03106 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NLLAEHGB_03107 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NLLAEHGB_03108 1.6e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NLLAEHGB_03109 9.2e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NLLAEHGB_03110 1.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NLLAEHGB_03111 2e-94 yqeG S hydrolase of the HAD superfamily
NLLAEHGB_03113 3.7e-139 yqeF E GDSL-like Lipase/Acylhydrolase
NLLAEHGB_03114 1.5e-140 3.5.1.104 G Polysaccharide deacetylase
NLLAEHGB_03115 4.2e-107 yqeD S SNARE associated Golgi protein
NLLAEHGB_03116 1.3e-17 2.3.1.57 K Acetyltransferase (GNAT) domain
NLLAEHGB_03117 2.2e-216 EGP Major facilitator Superfamily
NLLAEHGB_03118 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NLLAEHGB_03119 2.1e-151 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
NLLAEHGB_03120 2.2e-88 K Transcriptional regulator PadR-like family
NLLAEHGB_03121 2.6e-68 psiE S Belongs to the PsiE family
NLLAEHGB_03122 5.6e-239 yrkQ T Histidine kinase
NLLAEHGB_03123 2.9e-125 T Transcriptional regulator
NLLAEHGB_03124 2.7e-219 yrkO P Protein of unknown function (DUF418)
NLLAEHGB_03125 1.6e-102 yrkN K Acetyltransferase (GNAT) family
NLLAEHGB_03126 1.1e-98 adk 2.7.4.3 F adenylate kinase activity
NLLAEHGB_03127 1.7e-31 yyaR K acetyltransferase
NLLAEHGB_03128 4e-77 tetL EGP Major facilitator Superfamily
NLLAEHGB_03129 1.5e-81 yyaR K Acetyltransferase (GNAT) domain
NLLAEHGB_03130 1.8e-92 yrdA S DinB family
NLLAEHGB_03132 8.3e-148 S hydrolase
NLLAEHGB_03133 1.7e-145 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
NLLAEHGB_03134 1.2e-129 glvR K Helix-turn-helix domain, rpiR family
NLLAEHGB_03135 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
NLLAEHGB_03136 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NLLAEHGB_03137 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NLLAEHGB_03138 6.3e-184 romA S Beta-lactamase superfamily domain
NLLAEHGB_03139 1.2e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NLLAEHGB_03140 1.1e-164 yybE K Transcriptional regulator
NLLAEHGB_03141 1.2e-211 ynfM EGP Major facilitator Superfamily
NLLAEHGB_03142 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NLLAEHGB_03143 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NLLAEHGB_03144 3.9e-93 yrhH Q methyltransferase
NLLAEHGB_03146 8e-143 focA P Formate nitrite
NLLAEHGB_03147 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
NLLAEHGB_03148 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
NLLAEHGB_03149 3.5e-80 yrhD S Protein of unknown function (DUF1641)
NLLAEHGB_03150 4.6e-35 yrhC S YrhC-like protein
NLLAEHGB_03151 3.7e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NLLAEHGB_03152 4.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NLLAEHGB_03153 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NLLAEHGB_03154 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NLLAEHGB_03155 5.3e-27 yrzA S Protein of unknown function (DUF2536)
NLLAEHGB_03156 8.1e-70 yrrS S Protein of unknown function (DUF1510)
NLLAEHGB_03157 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NLLAEHGB_03158 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NLLAEHGB_03159 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
NLLAEHGB_03160 1.6e-246 yegQ O COG0826 Collagenase and related proteases
NLLAEHGB_03161 1.7e-173 yegQ O Peptidase U32
NLLAEHGB_03162 2.8e-117 yrrM 2.1.1.104 S O-methyltransferase
NLLAEHGB_03163 9.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NLLAEHGB_03164 7.1e-46 yrzB S Belongs to the UPF0473 family
NLLAEHGB_03165 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NLLAEHGB_03166 1.7e-41 yrzL S Belongs to the UPF0297 family
NLLAEHGB_03167 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NLLAEHGB_03168 2e-162 yrrI S AI-2E family transporter
NLLAEHGB_03169 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NLLAEHGB_03170 3.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
NLLAEHGB_03171 8e-109 gluC P ABC transporter
NLLAEHGB_03172 3.1e-108 glnP P ABC transporter
NLLAEHGB_03173 2.1e-08 S Protein of unknown function (DUF3918)
NLLAEHGB_03174 2.9e-30 yrzR
NLLAEHGB_03175 1.8e-83 yrrD S protein conserved in bacteria
NLLAEHGB_03176 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NLLAEHGB_03177 1.7e-18 S COG0457 FOG TPR repeat
NLLAEHGB_03178 2e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NLLAEHGB_03179 1e-212 iscS 2.8.1.7 E Cysteine desulfurase
NLLAEHGB_03180 7.8e-64 cymR K Transcriptional regulator
NLLAEHGB_03181 5.7e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NLLAEHGB_03182 7.4e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NLLAEHGB_03183 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NLLAEHGB_03184 8.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NLLAEHGB_03187 3.8e-274 lytH 3.5.1.28 M COG3103 SH3 domain protein
NLLAEHGB_03188 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NLLAEHGB_03189 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLLAEHGB_03190 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NLLAEHGB_03191 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NLLAEHGB_03192 1.7e-46 yrvD S Lipopolysaccharide assembly protein A domain
NLLAEHGB_03193 1.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NLLAEHGB_03194 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NLLAEHGB_03195 1.3e-50 yrzD S Post-transcriptional regulator
NLLAEHGB_03196 7.2e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NLLAEHGB_03197 1.8e-108 yrbG S membrane
NLLAEHGB_03198 2.4e-60 yrzE S Protein of unknown function (DUF3792)
NLLAEHGB_03199 2.5e-37 yajC U Preprotein translocase subunit YajC
NLLAEHGB_03200 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NLLAEHGB_03201 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NLLAEHGB_03202 1.6e-20 yrzS S Protein of unknown function (DUF2905)
NLLAEHGB_03203 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NLLAEHGB_03204 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NLLAEHGB_03205 4.8e-93 bofC S BofC C-terminal domain
NLLAEHGB_03207 1.4e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NLLAEHGB_03208 3.9e-146 safA M spore coat assembly protein SafA
NLLAEHGB_03209 5.3e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NLLAEHGB_03210 4.8e-154 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NLLAEHGB_03211 2.6e-146 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NLLAEHGB_03212 3.4e-39 S COG NOG14552 non supervised orthologous group
NLLAEHGB_03217 1.6e-08
NLLAEHGB_03224 1.3e-09
NLLAEHGB_03225 1.7e-122 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NLLAEHGB_03226 7e-95 yhaK S Putative zincin peptidase
NLLAEHGB_03227 9.9e-55 yhaI S Protein of unknown function (DUF1878)
NLLAEHGB_03228 8.6e-113 hpr K Negative regulator of protease production and sporulation
NLLAEHGB_03229 2.4e-38 yhaH S YtxH-like protein
NLLAEHGB_03230 2e-17
NLLAEHGB_03231 3.8e-77 trpP S Tryptophan transporter TrpP
NLLAEHGB_03232 5.4e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NLLAEHGB_03233 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NLLAEHGB_03234 3.3e-135 ecsA V transporter (ATP-binding protein)
NLLAEHGB_03235 1.5e-220 ecsB U ABC transporter
NLLAEHGB_03236 3.6e-123 ecsC S EcsC protein family
NLLAEHGB_03237 3e-223 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NLLAEHGB_03238 3.1e-243 yhfA C membrane
NLLAEHGB_03239 6e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NLLAEHGB_03240 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NLLAEHGB_03241 4.3e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NLLAEHGB_03242 2.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NLLAEHGB_03243 1.6e-274 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NLLAEHGB_03244 3.2e-101 yhgD K Transcriptional regulator
NLLAEHGB_03245 3.2e-277 yhgE S YhgE Pip N-terminal domain protein
NLLAEHGB_03246 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLLAEHGB_03248 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NLLAEHGB_03249 7.6e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NLLAEHGB_03250 7.9e-11 yhfH S YhfH-like protein
NLLAEHGB_03251 1.5e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NLLAEHGB_03252 3.5e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
NLLAEHGB_03253 7.7e-112 yhfK GM NmrA-like family
NLLAEHGB_03254 4e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NLLAEHGB_03255 8.7e-66 yhfM
NLLAEHGB_03256 6e-238 yhfN 3.4.24.84 O Peptidase M48
NLLAEHGB_03257 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NLLAEHGB_03258 1.6e-152 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NLLAEHGB_03259 2.2e-102 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NLLAEHGB_03260 2.7e-202 vraB 2.3.1.9 I Belongs to the thiolase family
NLLAEHGB_03261 1.6e-279 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NLLAEHGB_03262 2.1e-89 bioY S BioY family
NLLAEHGB_03263 9.1e-197 hemAT NT chemotaxis protein
NLLAEHGB_03264 4.8e-298 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NLLAEHGB_03265 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NLLAEHGB_03266 1.3e-32 yhzC S IDEAL
NLLAEHGB_03267 1.9e-109 comK K Competence transcription factor
NLLAEHGB_03268 3.9e-68 frataxin S Domain of unknown function (DU1801)
NLLAEHGB_03269 3.9e-68 frataxin S Domain of unknown function (DU1801)
NLLAEHGB_03270 1.3e-93 mepB S MepB protein
NLLAEHGB_03271 4.2e-127 yrpD S Domain of unknown function, YrpD
NLLAEHGB_03272 1.6e-42 yhjA S Excalibur calcium-binding domain
NLLAEHGB_03273 3.3e-47 S Belongs to the UPF0145 family
NLLAEHGB_03274 8.6e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLLAEHGB_03275 1.4e-27 yhjC S Protein of unknown function (DUF3311)
NLLAEHGB_03276 1.1e-59 yhjD
NLLAEHGB_03277 2.4e-110 yhjE S SNARE associated Golgi protein
NLLAEHGB_03278 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NLLAEHGB_03279 5e-276 yhjG CH FAD binding domain
NLLAEHGB_03280 9.7e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
NLLAEHGB_03281 8.1e-189 abrB S membrane
NLLAEHGB_03282 2.5e-209 blt EGP Major facilitator Superfamily
NLLAEHGB_03283 4.5e-109 K QacR-like protein, C-terminal region
NLLAEHGB_03284 7e-92 yhjR S Rubrerythrin
NLLAEHGB_03285 3e-125 ydfS S Protein of unknown function (DUF421)
NLLAEHGB_03286 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NLLAEHGB_03287 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NLLAEHGB_03288 8.7e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NLLAEHGB_03289 0.0 sbcC L COG0419 ATPase involved in DNA repair
NLLAEHGB_03290 1.3e-50 yisB V COG1403 Restriction endonuclease
NLLAEHGB_03291 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
NLLAEHGB_03292 1.9e-65 gerPE S Spore germination protein GerPE
NLLAEHGB_03293 3.1e-23 gerPD S Spore germination protein
NLLAEHGB_03294 1.4e-62 gerPC S Spore germination protein
NLLAEHGB_03295 6.2e-35 gerPB S cell differentiation
NLLAEHGB_03296 8.4e-34 gerPA S Spore germination protein
NLLAEHGB_03297 5e-07 yisI S Spo0E like sporulation regulatory protein
NLLAEHGB_03298 1.2e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NLLAEHGB_03299 1.1e-59 yisL S UPF0344 protein
NLLAEHGB_03300 3.1e-98 yisN S Protein of unknown function (DUF2777)
NLLAEHGB_03301 0.0 asnO 6.3.5.4 E Asparagine synthase
NLLAEHGB_03302 4.1e-133 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NLLAEHGB_03303 1.5e-245 yisQ V Mate efflux family protein
NLLAEHGB_03304 5.9e-160 yisR K Transcriptional regulator
NLLAEHGB_03305 2.4e-89 yisT S DinB family
NLLAEHGB_03306 3.5e-74 argO S Lysine exporter protein LysE YggA
NLLAEHGB_03307 1.1e-190 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NLLAEHGB_03308 3.7e-71 mcbG S Pentapeptide repeats (9 copies)
NLLAEHGB_03309 3.1e-80 yjcF S Acetyltransferase (GNAT) domain
NLLAEHGB_03310 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NLLAEHGB_03311 6.6e-55 yajQ S Belongs to the UPF0234 family
NLLAEHGB_03312 9e-161 cvfB S protein conserved in bacteria
NLLAEHGB_03313 4.1e-173 yufN S ABC transporter substrate-binding protein PnrA-like
NLLAEHGB_03314 1.4e-226 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
NLLAEHGB_03315 5.6e-244 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NLLAEHGB_03317 5.5e-158 yitS S protein conserved in bacteria
NLLAEHGB_03318 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NLLAEHGB_03319 2.9e-81 ipi S Intracellular proteinase inhibitor
NLLAEHGB_03320 4.4e-26 S Protein of unknown function (DUF3813)
NLLAEHGB_03321 3.5e-07
NLLAEHGB_03322 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NLLAEHGB_03323 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NLLAEHGB_03324 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NLLAEHGB_03325 1.4e-80 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NLLAEHGB_03326 3.9e-273 yitY C D-arabinono-1,4-lactone oxidase
NLLAEHGB_03327 1.6e-88 norB G Major Facilitator Superfamily
NLLAEHGB_03328 4.3e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NLLAEHGB_03329 1.6e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NLLAEHGB_03330 2.6e-138 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
NLLAEHGB_03331 8.9e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NLLAEHGB_03332 6.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NLLAEHGB_03333 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NLLAEHGB_03334 6e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NLLAEHGB_03335 1.2e-27 yjzC S YjzC-like protein
NLLAEHGB_03336 1.5e-23 yjzD S Protein of unknown function (DUF2929)
NLLAEHGB_03337 1.1e-138 yjaU I carboxylic ester hydrolase activity
NLLAEHGB_03338 1.5e-106 yjaV
NLLAEHGB_03339 1.9e-166 med S Transcriptional activator protein med
NLLAEHGB_03340 1.1e-26 comZ S ComZ
NLLAEHGB_03341 5.9e-32 yjzB
NLLAEHGB_03342 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLLAEHGB_03343 8.9e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NLLAEHGB_03344 5.6e-149 yjaZ O Zn-dependent protease
NLLAEHGB_03345 3.3e-183 appD P Belongs to the ABC transporter superfamily
NLLAEHGB_03346 5.9e-188 appF E Belongs to the ABC transporter superfamily
NLLAEHGB_03347 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NLLAEHGB_03348 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLLAEHGB_03349 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLLAEHGB_03350 5.5e-146 yjbA S Belongs to the UPF0736 family
NLLAEHGB_03351 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NLLAEHGB_03352 0.0 oppA E ABC transporter substrate-binding protein
NLLAEHGB_03353 4.6e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLLAEHGB_03354 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLLAEHGB_03355 2.7e-202 oppD P Belongs to the ABC transporter superfamily
NLLAEHGB_03356 2.1e-171 oppF E Belongs to the ABC transporter superfamily
NLLAEHGB_03357 8e-232 S Putative glycosyl hydrolase domain
NLLAEHGB_03358 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLLAEHGB_03359 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NLLAEHGB_03360 8.1e-109 yjbE P Integral membrane protein TerC family
NLLAEHGB_03361 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NLLAEHGB_03362 2.1e-221 yjbF S Competence protein
NLLAEHGB_03363 0.0 pepF E oligoendopeptidase F
NLLAEHGB_03364 5.8e-19
NLLAEHGB_03365 5.1e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NLLAEHGB_03366 4.8e-72 yjbI S Bacterial-like globin
NLLAEHGB_03367 4.5e-118 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NLLAEHGB_03368 4.1e-101 yjbK S protein conserved in bacteria
NLLAEHGB_03369 6e-61 yjbL S Belongs to the UPF0738 family
NLLAEHGB_03370 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
NLLAEHGB_03371 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NLLAEHGB_03372 1.3e-162 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NLLAEHGB_03373 1.4e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NLLAEHGB_03374 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NLLAEHGB_03375 2.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NLLAEHGB_03376 4.2e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NLLAEHGB_03377 1e-212 thiO 1.4.3.19 E Glycine oxidase
NLLAEHGB_03378 1.4e-30 thiS H Thiamine biosynthesis
NLLAEHGB_03379 3.8e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NLLAEHGB_03380 2.1e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NLLAEHGB_03381 1.7e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NLLAEHGB_03382 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NLLAEHGB_03383 3e-89 yjbX S Spore coat protein
NLLAEHGB_03384 6.9e-80 cotZ S Spore coat protein
NLLAEHGB_03385 1.6e-90 cotY S Spore coat protein Z
NLLAEHGB_03386 4.4e-75 cotX S Spore Coat Protein X and V domain
NLLAEHGB_03387 1.1e-23 cotW
NLLAEHGB_03388 1.2e-56 cotV S Spore Coat Protein X and V domain
NLLAEHGB_03389 8.7e-57 yjcA S Protein of unknown function (DUF1360)
NLLAEHGB_03393 3.8e-38 spoVIF S Stage VI sporulation protein F
NLLAEHGB_03394 0.0 yjcD 3.6.4.12 L DNA helicase
NLLAEHGB_03395 2.1e-36
NLLAEHGB_03396 3.7e-67 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
NLLAEHGB_03397 1.3e-53 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
NLLAEHGB_03398 4e-125 S ABC-2 type transporter
NLLAEHGB_03399 6.9e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
NLLAEHGB_03400 9.4e-36 K SpoVT / AbrB like domain
NLLAEHGB_03401 5e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLLAEHGB_03402 1.2e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NLLAEHGB_03403 5.5e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
NLLAEHGB_03404 5.4e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NLLAEHGB_03405 2.6e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NLLAEHGB_03407 8.4e-52 L Belongs to the 'phage' integrase family
NLLAEHGB_03408 7.8e-70 S Pfam Transposase IS66
NLLAEHGB_03409 1.6e-45 S Pfam Transposase IS66
NLLAEHGB_03410 3.9e-11
NLLAEHGB_03414 4.3e-17 K Cro/C1-type HTH DNA-binding domain
NLLAEHGB_03419 5.5e-11 S Abortive infection C-terminus
NLLAEHGB_03421 8.7e-31
NLLAEHGB_03422 4e-84
NLLAEHGB_03423 4e-23
NLLAEHGB_03424 5.4e-259 yobL S Bacterial EndoU nuclease
NLLAEHGB_03426 1.1e-40
NLLAEHGB_03427 4.1e-22
NLLAEHGB_03428 1.2e-08 S Uncharacterised protein family (UPF0715)
NLLAEHGB_03429 4e-12
NLLAEHGB_03430 1.2e-49 FG Scavenger mRNA decapping enzyme C-term binding
NLLAEHGB_03431 5.1e-25 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NLLAEHGB_03432 1.1e-35 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NLLAEHGB_03434 5e-165 bla 3.5.2.6 V beta-lactamase
NLLAEHGB_03435 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
NLLAEHGB_03436 3e-254 yfjF EGP Belongs to the major facilitator superfamily
NLLAEHGB_03437 3.9e-81 napB K helix_turn_helix multiple antibiotic resistance protein
NLLAEHGB_03438 9.2e-222 ganA 3.2.1.89 G arabinogalactan
NLLAEHGB_03439 1.1e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NLLAEHGB_03440 6.3e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NLLAEHGB_03441 1e-154 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NLLAEHGB_03447 1.6e-08
NLLAEHGB_03450 3.2e-53 L COG2963 Transposase and inactivated derivatives
NLLAEHGB_03451 2.3e-09
NLLAEHGB_03452 3.9e-215 patA 2.6.1.1 E Aminotransferase
NLLAEHGB_03453 6.8e-291 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
NLLAEHGB_03454 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NLLAEHGB_03455 7.5e-114 ykwD J protein with SCP PR1 domains
NLLAEHGB_03456 1.4e-156 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NLLAEHGB_03457 5.1e-266 mcpC NT chemotaxis protein
NLLAEHGB_03458 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
NLLAEHGB_03459 6.1e-38 splA S Transcriptional regulator
NLLAEHGB_03460 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NLLAEHGB_03461 2.1e-39 ptsH G phosphocarrier protein HPr
NLLAEHGB_03462 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NLLAEHGB_03463 1.9e-155 glcT K antiterminator
NLLAEHGB_03464 1e-176 ykvZ 5.1.1.1 K Transcriptional regulator
NLLAEHGB_03466 2.6e-205 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NLLAEHGB_03467 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NLLAEHGB_03468 2.7e-88 stoA CO thiol-disulfide
NLLAEHGB_03469 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NLLAEHGB_03470 6.9e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
NLLAEHGB_03471 3.9e-27
NLLAEHGB_03472 7.8e-25 ykvS S protein conserved in bacteria
NLLAEHGB_03473 1.7e-44 ykvR S Protein of unknown function (DUF3219)
NLLAEHGB_03474 2.7e-31 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NLLAEHGB_03475 4.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
NLLAEHGB_03476 7.5e-58 ykvN K Transcriptional regulator
NLLAEHGB_03478 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NLLAEHGB_03479 1.1e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NLLAEHGB_03480 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NLLAEHGB_03481 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NLLAEHGB_03482 3e-188
NLLAEHGB_03483 3.5e-183 ykvI S membrane
NLLAEHGB_03484 0.0 clpE O Belongs to the ClpA ClpB family
NLLAEHGB_03485 1.1e-136 motA N flagellar motor
NLLAEHGB_03486 2.7e-127 motB N Flagellar motor protein
NLLAEHGB_03487 1.5e-77 ykvE K transcriptional
NLLAEHGB_03488 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NLLAEHGB_03489 2.6e-10 S Spo0E like sporulation regulatory protein
NLLAEHGB_03490 4.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NLLAEHGB_03491 2.2e-116 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NLLAEHGB_03492 4.4e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NLLAEHGB_03493 6.1e-227 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NLLAEHGB_03494 4.1e-228 mtnE 2.6.1.83 E Aminotransferase
NLLAEHGB_03495 7.7e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NLLAEHGB_03496 4.2e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NLLAEHGB_03497 1.2e-194 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NLLAEHGB_03499 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NLLAEHGB_03500 0.0 kinE 2.7.13.3 T Histidine kinase
NLLAEHGB_03501 2e-191 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NLLAEHGB_03502 7.9e-24 ykzE
NLLAEHGB_03503 3.8e-114 ydfR S Protein of unknown function (DUF421)
NLLAEHGB_03504 1.3e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
NLLAEHGB_03505 4.1e-156 htpX O Belongs to the peptidase M48B family
NLLAEHGB_03506 7.8e-126 ykrK S Domain of unknown function (DUF1836)
NLLAEHGB_03507 2.5e-26 sspD S small acid-soluble spore protein
NLLAEHGB_03508 8.1e-120 rsgI S Anti-sigma factor N-terminus
NLLAEHGB_03509 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NLLAEHGB_03510 1.2e-135 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NLLAEHGB_03511 4.1e-101 ykoX S membrane-associated protein
NLLAEHGB_03512 4.2e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NLLAEHGB_03513 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NLLAEHGB_03514 2.2e-99 ykoP G polysaccharide deacetylase
NLLAEHGB_03515 5e-81 ykoM K transcriptional
NLLAEHGB_03516 3.1e-26 ykoL
NLLAEHGB_03517 1.9e-16
NLLAEHGB_03518 5.4e-53 tnrA K transcriptional
NLLAEHGB_03519 2.2e-238 mgtE P Acts as a magnesium transporter
NLLAEHGB_03521 2.3e-245 ydhD M Glycosyl hydrolase
NLLAEHGB_03522 5.3e-99 ykoE S ABC-type cobalt transport system, permease component
NLLAEHGB_03523 4.5e-311 P ABC transporter, ATP-binding protein
NLLAEHGB_03524 4.6e-132 ykoC P Cobalt transport protein
NLLAEHGB_03525 5.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NLLAEHGB_03526 2.9e-176 isp O Belongs to the peptidase S8 family
NLLAEHGB_03527 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NLLAEHGB_03528 3.2e-119 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NLLAEHGB_03529 9.4e-217 hcaT 1.5.1.2 EGP Major facilitator Superfamily
NLLAEHGB_03530 1.5e-131 M PFAM Collagen triple helix repeat (20 copies)
NLLAEHGB_03531 1.5e-216 M Glycosyl transferase family 2
NLLAEHGB_03533 8.9e-59 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NLLAEHGB_03534 4.2e-71 ohrB O Organic hydroperoxide resistance protein
NLLAEHGB_03535 6.1e-88 ohrR K COG1846 Transcriptional regulators
NLLAEHGB_03536 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NLLAEHGB_03537 3.6e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NLLAEHGB_03538 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NLLAEHGB_03539 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NLLAEHGB_03540 3.4e-49 ykkD P Multidrug resistance protein
NLLAEHGB_03541 1.8e-52 ykkC P Multidrug resistance protein
NLLAEHGB_03542 1.4e-101 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NLLAEHGB_03543 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NLLAEHGB_03544 7.7e-160 ykgA E Amidinotransferase
NLLAEHGB_03545 3.9e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
NLLAEHGB_03546 9.6e-183 ykfD E Belongs to the ABC transporter superfamily
NLLAEHGB_03547 8.3e-173 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NLLAEHGB_03548 2.3e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NLLAEHGB_03549 1.5e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NLLAEHGB_03550 0.0 dppE E ABC transporter substrate-binding protein
NLLAEHGB_03551 7.7e-191 dppD P Belongs to the ABC transporter superfamily
NLLAEHGB_03552 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLLAEHGB_03553 6.4e-160 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLLAEHGB_03554 6.5e-156 dppA E D-aminopeptidase
NLLAEHGB_03556 6.9e-284 yubD P Major Facilitator Superfamily
NLLAEHGB_03557 3.3e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NLLAEHGB_03559 1.4e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NLLAEHGB_03560 7.7e-310 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NLLAEHGB_03561 5e-184 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NLLAEHGB_03562 1.5e-242 steT E amino acid
NLLAEHGB_03563 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NLLAEHGB_03564 2e-175 pit P phosphate transporter
NLLAEHGB_03565 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NLLAEHGB_03566 8.7e-23 spoIISB S Stage II sporulation protein SB
NLLAEHGB_03567 2.3e-167 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NLLAEHGB_03568 1.3e-38 xhlB S SPP1 phage holin
NLLAEHGB_03569 8.7e-38 xhlA S Haemolysin XhlA
NLLAEHGB_03570 3e-139 xepA
NLLAEHGB_03571 1.7e-30 xkdX
NLLAEHGB_03573 1.3e-67
NLLAEHGB_03574 2.1e-26
NLLAEHGB_03575 2.2e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NLLAEHGB_03576 6.7e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NLLAEHGB_03577 3.2e-58 xkdS S Protein of unknown function (DUF2634)
NLLAEHGB_03578 7.2e-32 xkdR S Protein of unknown function (DUF2577)
NLLAEHGB_03579 5.5e-162 xkdQ 3.2.1.96 G NLP P60 protein
NLLAEHGB_03580 6.6e-111 xkdP S Lysin motif
NLLAEHGB_03581 5.2e-181 xkdO L Transglycosylase SLT domain
NLLAEHGB_03582 3.4e-19
NLLAEHGB_03583 5.7e-74 S Phage XkdN-like tail assembly chaperone protein, TAC
NLLAEHGB_03584 2e-74 xkdM S Phage tail tube protein
NLLAEHGB_03585 3.8e-225 xkdK S Phage tail sheath C-terminal domain
NLLAEHGB_03586 3.1e-14
NLLAEHGB_03587 4.9e-57 xkdJ
NLLAEHGB_03588 3.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
NLLAEHGB_03589 4.2e-43 yqbH S Domain of unknown function (DUF3599)
NLLAEHGB_03590 7.4e-46 yqbG S Protein of unknown function (DUF3199)
NLLAEHGB_03591 1e-157 xkdG S Phage capsid family
NLLAEHGB_03592 2.8e-90 xkdF 2.1.1.72 L Putative phage serine protease XkdF
NLLAEHGB_03593 7.9e-242 yqbA S portal protein
NLLAEHGB_03594 3.6e-209 xtmB S phage terminase, large subunit
NLLAEHGB_03595 6.8e-110 xtmA L phage terminase small subunit
NLLAEHGB_03596 4.9e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NLLAEHGB_03597 1.2e-10 yqaO S Phage-like element PBSX protein XtrA
NLLAEHGB_03600 8.5e-153 xkdC L Bacterial dnaA protein
NLLAEHGB_03602 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
NLLAEHGB_03603 7.8e-111 xkdA E IrrE N-terminal-like domain
NLLAEHGB_03605 2.1e-111 yjqB S phage-related replication protein
NLLAEHGB_03606 4.7e-61 yjqA S Bacterial PH domain
NLLAEHGB_03607 5e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NLLAEHGB_03609 4.9e-215 S response regulator aspartate phosphatase
NLLAEHGB_03610 2.1e-79 yjoA S DinB family
NLLAEHGB_03611 8.7e-131 MA20_18170 S membrane transporter protein
NLLAEHGB_03612 2.2e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NLLAEHGB_03613 1.5e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NLLAEHGB_03614 1.3e-182 exuR K transcriptional
NLLAEHGB_03615 2.1e-252 yjmB G symporter YjmB
NLLAEHGB_03616 1.3e-278 uxaC 5.3.1.12 G glucuronate isomerase
NLLAEHGB_03617 1.3e-218 yjlD 1.6.99.3 C NADH dehydrogenase
NLLAEHGB_03618 7e-66 yjlC S Protein of unknown function (DUF1641)
NLLAEHGB_03619 5.7e-91 yjlB S Cupin domain
NLLAEHGB_03620 1.6e-177 yjlA EG Putative multidrug resistance efflux transporter
NLLAEHGB_03621 2.2e-131 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
NLLAEHGB_03622 5.8e-125 ybbM S transport system, permease component
NLLAEHGB_03623 3.1e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NLLAEHGB_03624 6.8e-29
NLLAEHGB_03625 3.7e-221 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NLLAEHGB_03626 7.9e-227 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NLLAEHGB_03627 5.3e-90 yjgD S Protein of unknown function (DUF1641)
NLLAEHGB_03628 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
NLLAEHGB_03629 5.9e-100 yjgB S Domain of unknown function (DUF4309)
NLLAEHGB_03630 1.1e-68 T PhoQ Sensor
NLLAEHGB_03631 7.5e-22 yjfB S Putative motility protein
NLLAEHGB_03633 8.1e-106 yhiD S MgtC SapB transporter
NLLAEHGB_03634 5e-51 K helix_turn_helix multiple antibiotic resistance protein
NLLAEHGB_03635 2.6e-34
NLLAEHGB_03636 4.4e-126 5.4.2.6 S Haloacid dehalogenase-like hydrolase
NLLAEHGB_03637 5.7e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
NLLAEHGB_03638 4e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
NLLAEHGB_03639 2.2e-48 lacF 2.7.1.207 G phosphotransferase system
NLLAEHGB_03640 1.3e-28 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLLAEHGB_03641 7.8e-25 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLLAEHGB_03644 1.3e-43 S Ecdysteroid kinase
NLLAEHGB_03645 2.6e-44 S Ecdysteroid kinase
NLLAEHGB_03646 1.1e-23 cheV 2.7.13.3 T Chemotaxis protein CheV
NLLAEHGB_03647 1.2e-44 L COG2963 Transposase and inactivated derivatives
NLLAEHGB_03648 7.7e-115 yyaS S Membrane
NLLAEHGB_03649 4.5e-115 yyaS S Membrane
NLLAEHGB_03652 2e-08
NLLAEHGB_03657 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLLAEHGB_03658 1.1e-183 ytxK 2.1.1.72 L DNA methylase
NLLAEHGB_03659 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NLLAEHGB_03660 1.6e-60 ytfJ S Sporulation protein YtfJ
NLLAEHGB_03661 1.3e-109 ytfI S Protein of unknown function (DUF2953)
NLLAEHGB_03662 5.9e-88 yteJ S RDD family
NLLAEHGB_03663 6.4e-182 sppA OU signal peptide peptidase SppA
NLLAEHGB_03664 3.3e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NLLAEHGB_03665 2.2e-311 ytcJ S amidohydrolase
NLLAEHGB_03666 1.6e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NLLAEHGB_03667 3.9e-31 sspB S spore protein
NLLAEHGB_03668 1.1e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NLLAEHGB_03669 1.1e-209 iscS2 2.8.1.7 E Cysteine desulfurase
NLLAEHGB_03670 5.3e-240 braB E Component of the transport system for branched-chain amino acids
NLLAEHGB_03671 4.3e-263 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NLLAEHGB_03672 1.5e-152 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NLLAEHGB_03673 7.7e-109 yttP K Transcriptional regulator
NLLAEHGB_03674 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
NLLAEHGB_03675 2.7e-284 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NLLAEHGB_03676 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NLLAEHGB_03677 7.2e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NLLAEHGB_03678 2.2e-07 S aspartate phosphatase
NLLAEHGB_03680 1.5e-23
NLLAEHGB_03681 1.5e-17 L Integrase
NLLAEHGB_03682 4.9e-221 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NLLAEHGB_03683 7.3e-09
NLLAEHGB_03684 4.4e-47 yhbO 1.11.1.6, 3.5.1.124 S protease
NLLAEHGB_03686 5.9e-140 E GDSL-like Lipase/Acylhydrolase family
NLLAEHGB_03687 1.1e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLLAEHGB_03688 4.4e-149 K Transcriptional regulator
NLLAEHGB_03689 6.8e-125 azlC E AzlC protein
NLLAEHGB_03690 2.5e-47 azlD S Branched-chain amino acid transport protein (AzlD)
NLLAEHGB_03691 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NLLAEHGB_03692 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NLLAEHGB_03693 8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NLLAEHGB_03694 7.1e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
NLLAEHGB_03695 2.3e-231 acuC BQ histone deacetylase
NLLAEHGB_03696 1.4e-119 motS N Flagellar motor protein
NLLAEHGB_03697 5.6e-144 motA N flagellar motor
NLLAEHGB_03698 2.9e-182 ccpA K catabolite control protein A
NLLAEHGB_03699 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NLLAEHGB_03700 1.7e-43 ytxJ O Protein of unknown function (DUF2847)
NLLAEHGB_03701 1.7e-16 ytxH S COG4980 Gas vesicle protein
NLLAEHGB_03702 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NLLAEHGB_03703 4.2e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NLLAEHGB_03704 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NLLAEHGB_03705 7e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLLAEHGB_03706 3.7e-148 ytpQ S Belongs to the UPF0354 family
NLLAEHGB_03707 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NLLAEHGB_03708 2.7e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NLLAEHGB_03709 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NLLAEHGB_03710 1.7e-51 ytzB S small secreted protein
NLLAEHGB_03711 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NLLAEHGB_03712 1.7e-164 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NLLAEHGB_03713 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NLLAEHGB_03714 3.5e-45 ytzH S YtzH-like protein
NLLAEHGB_03715 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
NLLAEHGB_03716 4e-178 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NLLAEHGB_03717 1.2e-166 ytlQ
NLLAEHGB_03718 1.8e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NLLAEHGB_03719 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NLLAEHGB_03720 7.8e-271 pepV 3.5.1.18 E Dipeptidase
NLLAEHGB_03721 5.3e-229 pbuO S permease
NLLAEHGB_03722 4.9e-218 ythQ U Bacterial ABC transporter protein EcsB
NLLAEHGB_03723 4.9e-128 ythP V ABC transporter
NLLAEHGB_03724 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NLLAEHGB_03725 8.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NLLAEHGB_03726 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NLLAEHGB_03727 3.3e-236 ytfP S HI0933-like protein
NLLAEHGB_03728 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NLLAEHGB_03729 9e-26 yteV S Sporulation protein Cse60
NLLAEHGB_03730 5.7e-186 msmR K Transcriptional regulator
NLLAEHGB_03731 5.2e-245 msmE G Bacterial extracellular solute-binding protein
NLLAEHGB_03732 7.4e-169 amyD G Binding-protein-dependent transport system inner membrane component
NLLAEHGB_03733 1.4e-142 amyC P ABC transporter (permease)
NLLAEHGB_03734 7.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NLLAEHGB_03735 5.4e-86 M Acetyltransferase (GNAT) domain
NLLAEHGB_03736 2.1e-51 ytwF P Sulfurtransferase
NLLAEHGB_03737 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NLLAEHGB_03738 1.2e-52 ytvB S Protein of unknown function (DUF4257)
NLLAEHGB_03739 6.2e-140 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NLLAEHGB_03740 2.1e-208 yttB EGP Major facilitator Superfamily
NLLAEHGB_03741 1.5e-129 ywaF S Integral membrane protein
NLLAEHGB_03742 0.0 bceB V ABC transporter (permease)
NLLAEHGB_03743 9.8e-135 bceA V ABC transporter, ATP-binding protein
NLLAEHGB_03744 9.2e-170 T PhoQ Sensor
NLLAEHGB_03745 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLLAEHGB_03746 4.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NLLAEHGB_03747 1.3e-125 ytrE V ABC transporter, ATP-binding protein
NLLAEHGB_03748 8.8e-160
NLLAEHGB_03749 7e-165 P ABC-2 family transporter protein
NLLAEHGB_03750 2.6e-167 S ABC-2 family transporter protein
NLLAEHGB_03751 3.8e-162 ytrB P abc transporter atp-binding protein
NLLAEHGB_03752 3.9e-66 ytrA K GntR family transcriptional regulator
NLLAEHGB_03754 4.8e-39 ytzC S Protein of unknown function (DUF2524)
NLLAEHGB_03755 3.5e-189 K helix_turn_helix, Arsenical Resistance Operon Repressor
NLLAEHGB_03756 5.1e-285 norB EGP COG0477 Permeases of the major facilitator superfamily
NLLAEHGB_03757 2.1e-190 yhcC S Fe-S oxidoreductase
NLLAEHGB_03758 3.9e-107 ytqB J Putative rRNA methylase
NLLAEHGB_03760 2.8e-143 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
NLLAEHGB_03761 1.1e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NLLAEHGB_03762 5e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
NLLAEHGB_03763 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NLLAEHGB_03764 1.9e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NLLAEHGB_03765 0.0 asnB 6.3.5.4 E Asparagine synthase
NLLAEHGB_03766 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NLLAEHGB_03767 1.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NLLAEHGB_03768 1.6e-38 ytmB S Protein of unknown function (DUF2584)
NLLAEHGB_03769 6.1e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NLLAEHGB_03770 3.3e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NLLAEHGB_03771 3.2e-144 ytlC P ABC transporter
NLLAEHGB_03772 1.7e-140 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NLLAEHGB_03773 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NLLAEHGB_03774 1.7e-61 ytkC S Bacteriophage holin family
NLLAEHGB_03775 1.6e-76 dps P Belongs to the Dps family
NLLAEHGB_03777 3.6e-76 ytkA S YtkA-like
NLLAEHGB_03778 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NLLAEHGB_03779 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NLLAEHGB_03780 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NLLAEHGB_03781 3e-40 rpmE2 J Ribosomal protein L31
NLLAEHGB_03782 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
NLLAEHGB_03783 2.9e-185 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NLLAEHGB_03784 2.3e-24 S Domain of Unknown Function (DUF1540)
NLLAEHGB_03785 2.1e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NLLAEHGB_03786 1.2e-277 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NLLAEHGB_03787 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NLLAEHGB_03788 1.7e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NLLAEHGB_03789 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NLLAEHGB_03790 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
NLLAEHGB_03791 2e-132 dksA T COG1734 DnaK suppressor protein
NLLAEHGB_03792 3.4e-77 tspO T membrane
NLLAEHGB_03799 3.4e-62 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLLAEHGB_03800 2.2e-61 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLLAEHGB_03801 3.7e-82 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NLLAEHGB_03802 2.4e-81 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NLLAEHGB_03803 0.0 pksJ Q Polyketide synthase of type I
NLLAEHGB_03804 0.0 pfaA Q Polyketide synthase of type I
NLLAEHGB_03805 0.0 Q Polyketide synthase of type I
NLLAEHGB_03806 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NLLAEHGB_03807 2.6e-219 eryK 1.14.13.154 C Cytochrome P450
NLLAEHGB_03808 1.9e-239 pksG 2.3.3.10 I synthase
NLLAEHGB_03809 7.5e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NLLAEHGB_03810 3.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLLAEHGB_03811 5.5e-175 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NLLAEHGB_03812 5.5e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NLLAEHGB_03813 1.1e-258 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NLLAEHGB_03814 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
NLLAEHGB_03815 6.6e-74 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLLAEHGB_03817 2.5e-176 yueF S transporter activity
NLLAEHGB_03819 7.6e-58 S YolD-like protein
NLLAEHGB_03820 9.4e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLLAEHGB_03821 6.6e-89 yqjY K acetyltransferase
NLLAEHGB_03822 4.7e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NLLAEHGB_03823 5.1e-176 yqkA K GrpB protein
NLLAEHGB_03824 7.7e-61 yqkB S Belongs to the HesB IscA family
NLLAEHGB_03825 3.2e-39 yqkC S Protein of unknown function (DUF2552)
NLLAEHGB_03826 1.6e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NLLAEHGB_03828 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NLLAEHGB_03830 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NLLAEHGB_03831 2.4e-220 yqxK 3.6.4.12 L DNA helicase
NLLAEHGB_03832 3e-57 ansR K Transcriptional regulator
NLLAEHGB_03833 1.9e-186 ansA 3.5.1.1 EJ L-asparaginase
NLLAEHGB_03834 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NLLAEHGB_03835 4.2e-240 mleN C Na H antiporter
NLLAEHGB_03836 7.7e-244 mleA 1.1.1.38 C malic enzyme
NLLAEHGB_03837 5.7e-22
NLLAEHGB_03838 1.7e-34 yqkK
NLLAEHGB_03840 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NLLAEHGB_03841 1.9e-80 fur P Belongs to the Fur family
NLLAEHGB_03842 5.4e-36 S Protein of unknown function (DUF4227)
NLLAEHGB_03843 3.7e-165 xerD L recombinase XerD
NLLAEHGB_03844 4.7e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NLLAEHGB_03845 6.4e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NLLAEHGB_03846 1.8e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NLLAEHGB_03847 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NLLAEHGB_03848 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NLLAEHGB_03849 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NLLAEHGB_03850 3.7e-111 spoVAA S Stage V sporulation protein AA
NLLAEHGB_03851 3.9e-60 spoVAB S Stage V sporulation protein AB
NLLAEHGB_03852 1.3e-78 spoVAC S stage V sporulation protein AC
NLLAEHGB_03853 2.9e-190 spoVAD I Stage V sporulation protein AD
NLLAEHGB_03854 3.8e-57 spoVAEB S stage V sporulation protein
NLLAEHGB_03855 1.8e-110 spoVAEA S stage V sporulation protein
NLLAEHGB_03856 1.4e-270 spoVAF EG Stage V sporulation protein AF
NLLAEHGB_03857 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NLLAEHGB_03858 3e-154 ypuA S Secreted protein
NLLAEHGB_03859 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NLLAEHGB_03860 4.8e-82 ccdC1 O Protein of unknown function (DUF1453)
NLLAEHGB_03861 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NLLAEHGB_03862 1.7e-49 ypuD
NLLAEHGB_03863 6.2e-210 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NLLAEHGB_03864 1e-111 ribE 2.5.1.9 H Riboflavin synthase
NLLAEHGB_03865 4.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NLLAEHGB_03866 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NLLAEHGB_03867 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLLAEHGB_03868 1.7e-93 ypuF S Domain of unknown function (DUF309)
NLLAEHGB_03870 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NLLAEHGB_03871 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NLLAEHGB_03872 1.3e-93 ypuI S Protein of unknown function (DUF3907)
NLLAEHGB_03873 1.1e-214 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NLLAEHGB_03874 2e-103 spmA S Spore maturation protein
NLLAEHGB_03875 1.3e-88 spmB S Spore maturation protein
NLLAEHGB_03876 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NLLAEHGB_03877 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NLLAEHGB_03878 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NLLAEHGB_03879 1.9e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NLLAEHGB_03880 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLLAEHGB_03881 0.0 resE 2.7.13.3 T Histidine kinase
NLLAEHGB_03882 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NLLAEHGB_03883 4.2e-195 rsiX
NLLAEHGB_03884 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLLAEHGB_03885 1.4e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NLLAEHGB_03886 3.6e-41 fer C Ferredoxin
NLLAEHGB_03887 1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
NLLAEHGB_03888 3e-270 recQ 3.6.4.12 L DNA helicase
NLLAEHGB_03889 1.9e-98 ypbD S metal-dependent membrane protease
NLLAEHGB_03890 1.4e-80 ypbE M Lysin motif
NLLAEHGB_03891 1.7e-84 ypbF S Protein of unknown function (DUF2663)
NLLAEHGB_03892 4.8e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
NLLAEHGB_03893 5.7e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NLLAEHGB_03894 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NLLAEHGB_03895 9e-189 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NLLAEHGB_03896 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
NLLAEHGB_03897 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NLLAEHGB_03898 2.1e-252 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NLLAEHGB_03899 1.6e-61 ypfA M Flagellar protein YcgR
NLLAEHGB_03900 1.9e-12 S Family of unknown function (DUF5359)
NLLAEHGB_03901 9.5e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NLLAEHGB_03902 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
NLLAEHGB_03903 2e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NLLAEHGB_03904 4.7e-08 S YpzI-like protein
NLLAEHGB_03905 1.1e-104 yphA
NLLAEHGB_03906 2.1e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NLLAEHGB_03907 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NLLAEHGB_03908 3.3e-16 yphE S Protein of unknown function (DUF2768)
NLLAEHGB_03909 2.8e-134 yphF
NLLAEHGB_03910 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NLLAEHGB_03911 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NLLAEHGB_03912 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
NLLAEHGB_03913 3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NLLAEHGB_03914 1.6e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NLLAEHGB_03915 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NLLAEHGB_03916 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NLLAEHGB_03917 5.4e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NLLAEHGB_03918 8.5e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NLLAEHGB_03919 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NLLAEHGB_03920 1.9e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NLLAEHGB_03921 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NLLAEHGB_03922 9.6e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NLLAEHGB_03923 4.1e-160 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NLLAEHGB_03924 5.6e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NLLAEHGB_03925 9.5e-118 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NLLAEHGB_03926 2.1e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NLLAEHGB_03927 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NLLAEHGB_03928 1.1e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NLLAEHGB_03929 9.2e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NLLAEHGB_03930 8.1e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NLLAEHGB_03935 3.1e-33 L transposase activity

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)