ORF_ID e_value Gene_name EC_number CAZy COGs Description
NMELFEPI_00001 2.4e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NMELFEPI_00002 1.2e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NMELFEPI_00003 3.4e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NMELFEPI_00004 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMELFEPI_00005 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMELFEPI_00006 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
NMELFEPI_00007 7.3e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NMELFEPI_00008 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NMELFEPI_00009 3.5e-158 corA P CorA-like Mg2+ transporter protein
NMELFEPI_00010 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NMELFEPI_00011 4.8e-76 rplI J Binds to the 23S rRNA
NMELFEPI_00012 1.6e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NMELFEPI_00013 1e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NMELFEPI_00014 2.2e-218 I Protein of unknown function (DUF2974)
NMELFEPI_00015 0.0
NMELFEPI_00017 1.1e-245 steT E amino acid
NMELFEPI_00019 1.2e-224 S Sterol carrier protein domain
NMELFEPI_00020 5.5e-166 arbZ I Acyltransferase
NMELFEPI_00021 1.1e-115 ywnB S NAD(P)H-binding
NMELFEPI_00022 2.6e-126 S Protein of unknown function (DUF975)
NMELFEPI_00023 3.4e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NMELFEPI_00024 6.2e-154 yitS S EDD domain protein, DegV family
NMELFEPI_00025 3.5e-17
NMELFEPI_00026 1.2e-291 V ABC-type multidrug transport system, ATPase and permease components
NMELFEPI_00027 3.7e-140 ropB K Helix-turn-helix domain
NMELFEPI_00028 0.0 tetP J elongation factor G
NMELFEPI_00029 4.6e-236 clcA P chloride
NMELFEPI_00030 0.0 pepO 3.4.24.71 O Peptidase family M13
NMELFEPI_00031 3.3e-142 ropB K Helix-turn-helix XRE-family like proteins
NMELFEPI_00032 8.6e-200 XK27_02480 EGP Major facilitator Superfamily
NMELFEPI_00033 1.2e-191 L COG2826 Transposase and inactivated derivatives, IS30 family
NMELFEPI_00034 2.3e-165 P CorA-like Mg2+ transporter protein
NMELFEPI_00036 4.2e-40 S Transglycosylase associated protein
NMELFEPI_00037 2e-160 xth 3.1.11.2 L exodeoxyribonuclease III
NMELFEPI_00038 0.0 L Helicase C-terminal domain protein
NMELFEPI_00039 4.7e-136 S Alpha beta hydrolase
NMELFEPI_00040 1.7e-27
NMELFEPI_00041 1.1e-171 K AI-2E family transporter
NMELFEPI_00042 1.1e-250 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
NMELFEPI_00043 1.7e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NMELFEPI_00044 1.3e-97 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
NMELFEPI_00045 1.5e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMELFEPI_00046 0.0 S domain, Protein
NMELFEPI_00047 1.6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
NMELFEPI_00048 2.2e-16 S domain, Protein
NMELFEPI_00049 5e-298 E amino acid
NMELFEPI_00050 2.9e-248 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMELFEPI_00051 2.2e-168 K LysR substrate binding domain
NMELFEPI_00052 0.0 1.3.5.4 C FAD binding domain
NMELFEPI_00053 1.3e-241 brnQ U Component of the transport system for branched-chain amino acids
NMELFEPI_00054 1.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NMELFEPI_00055 7.9e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NMELFEPI_00056 1.1e-62 S Peptidase propeptide and YPEB domain
NMELFEPI_00057 2.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NMELFEPI_00058 2.2e-249 yhjX_2 P Major Facilitator Superfamily
NMELFEPI_00059 1e-246 yhjX_2 P Major Facilitator Superfamily
NMELFEPI_00060 4.7e-165 arbZ I Phosphate acyltransferases
NMELFEPI_00061 1.4e-186 arbY M Glycosyl transferase family 8
NMELFEPI_00062 3.8e-184 arbY M Glycosyl transferase family 8
NMELFEPI_00063 2.3e-153 arbx M Glycosyl transferase family 8
NMELFEPI_00064 6.8e-147 arbV 2.3.1.51 I Acyl-transferase
NMELFEPI_00067 2.6e-129 K response regulator
NMELFEPI_00068 0.0 vicK 2.7.13.3 T Histidine kinase
NMELFEPI_00069 3e-251 yycH S YycH protein
NMELFEPI_00070 3.5e-146 yycI S YycH protein
NMELFEPI_00071 2.4e-147 vicX 3.1.26.11 S domain protein
NMELFEPI_00072 6.4e-176 htrA 3.4.21.107 O serine protease
NMELFEPI_00073 1.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NMELFEPI_00074 1.2e-109 P Cobalt transport protein
NMELFEPI_00075 1.6e-233 cbiO1 S ABC transporter, ATP-binding protein
NMELFEPI_00076 2.6e-95 S ABC-type cobalt transport system, permease component
NMELFEPI_00077 1.3e-160 K helix_turn_helix, arabinose operon control protein
NMELFEPI_00078 2.9e-162 htpX O Belongs to the peptidase M48B family
NMELFEPI_00079 1.6e-89 lemA S LemA family
NMELFEPI_00080 3.3e-179 ybiR P Citrate transporter
NMELFEPI_00081 1.7e-64 S Iron-sulphur cluster biosynthesis
NMELFEPI_00082 1.7e-16
NMELFEPI_00083 7.8e-120
NMELFEPI_00085 4.6e-241 ydaM M Glycosyl transferase
NMELFEPI_00086 1.8e-201 G Glycosyl hydrolases family 8
NMELFEPI_00087 4.5e-120 yfbR S HD containing hydrolase-like enzyme
NMELFEPI_00088 1.6e-174 L HNH nucleases
NMELFEPI_00089 2e-45
NMELFEPI_00090 7.3e-138 glnQ E ABC transporter, ATP-binding protein
NMELFEPI_00091 5.5e-300 glnP P ABC transporter permease
NMELFEPI_00092 1.4e-115 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NMELFEPI_00093 3.7e-63 yeaO S Protein of unknown function, DUF488
NMELFEPI_00094 2.4e-123 terC P Integral membrane protein TerC family
NMELFEPI_00095 9.2e-87 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
NMELFEPI_00096 1e-134 cobB K SIR2 family
NMELFEPI_00097 2.6e-80
NMELFEPI_00098 1.1e-288 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMELFEPI_00099 2.1e-123 yugP S Putative neutral zinc metallopeptidase
NMELFEPI_00100 5.9e-174 S Alpha/beta hydrolase of unknown function (DUF915)
NMELFEPI_00101 4.2e-138 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMELFEPI_00103 1.8e-157 ypuA S Protein of unknown function (DUF1002)
NMELFEPI_00104 6.7e-153 epsV 2.7.8.12 S glycosyl transferase family 2
NMELFEPI_00105 4e-124 S Alpha/beta hydrolase family
NMELFEPI_00106 4.2e-59
NMELFEPI_00107 4.5e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMELFEPI_00108 2.2e-217 cycA E Amino acid permease
NMELFEPI_00109 3.8e-114 luxT K Bacterial regulatory proteins, tetR family
NMELFEPI_00110 6.7e-124
NMELFEPI_00111 2.3e-263 S Cysteine-rich secretory protein family
NMELFEPI_00112 5.3e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NMELFEPI_00113 2.1e-81
NMELFEPI_00114 1.7e-174 L Psort location Cytoplasmic, score
NMELFEPI_00115 2.3e-271 yjcE P Sodium proton antiporter
NMELFEPI_00116 1.4e-169 yibE S overlaps another CDS with the same product name
NMELFEPI_00117 4.5e-119 yibF S overlaps another CDS with the same product name
NMELFEPI_00118 2.6e-149 I alpha/beta hydrolase fold
NMELFEPI_00119 0.0 G Belongs to the glycosyl hydrolase 31 family
NMELFEPI_00120 2.5e-127 XK27_08435 K UTRA
NMELFEPI_00121 2.5e-214 agaS G SIS domain
NMELFEPI_00122 3.4e-227 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NMELFEPI_00123 2.5e-83 2.7.1.191 G PTS system sorbose subfamily IIB component
NMELFEPI_00124 3.4e-129 XK27_08455 G PTS system sorbose-specific iic component
NMELFEPI_00125 7.1e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
NMELFEPI_00126 7.9e-67 2.7.1.191 G PTS system fructose IIA component
NMELFEPI_00127 3.7e-243 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMELFEPI_00128 6.8e-215 S zinc-ribbon domain
NMELFEPI_00129 4.8e-87 ntd 2.4.2.6 F Nucleoside
NMELFEPI_00130 1.7e-99 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NMELFEPI_00131 1.1e-130 XK27_08440 K UTRA domain
NMELFEPI_00132 2.8e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
NMELFEPI_00133 1e-87 uspA T universal stress protein
NMELFEPI_00135 9.8e-169 phnD P Phosphonate ABC transporter
NMELFEPI_00136 8.1e-140 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NMELFEPI_00137 2e-130 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NMELFEPI_00138 1.2e-146 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NMELFEPI_00139 7.3e-83
NMELFEPI_00140 8.4e-273 S Calcineurin-like phosphoesterase
NMELFEPI_00141 0.0 asnB 6.3.5.4 E Asparagine synthase
NMELFEPI_00142 3.6e-265 yxbA 6.3.1.12 S ATP-grasp enzyme
NMELFEPI_00143 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NMELFEPI_00144 3.1e-130 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NMELFEPI_00145 2.9e-105 S Iron-sulfur cluster assembly protein
NMELFEPI_00146 6.4e-229 XK27_04775 S PAS domain
NMELFEPI_00147 8e-227 yttB EGP Major facilitator Superfamily
NMELFEPI_00148 1.4e-184 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
NMELFEPI_00149 2.2e-174 D nuclear chromosome segregation
NMELFEPI_00150 4.4e-135 rpl K Helix-turn-helix domain, rpiR family
NMELFEPI_00151 1.1e-159 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
NMELFEPI_00152 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NMELFEPI_00153 0.0 pepO 3.4.24.71 O Peptidase family M13
NMELFEPI_00154 0.0 S Bacterial membrane protein, YfhO
NMELFEPI_00155 2.1e-227 L COG3547 Transposase and inactivated derivatives
NMELFEPI_00156 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NMELFEPI_00157 0.0 kup P Transport of potassium into the cell
NMELFEPI_00158 0.0 kup P Transport of potassium into the cell
NMELFEPI_00159 1e-72
NMELFEPI_00160 5.5e-115
NMELFEPI_00161 4.2e-27
NMELFEPI_00162 8.2e-35 S Protein of unknown function (DUF2922)
NMELFEPI_00163 7.7e-214 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NMELFEPI_00164 6.1e-231 lysA2 M Glycosyl hydrolases family 25
NMELFEPI_00165 3.6e-143 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
NMELFEPI_00166 0.0 yjbQ P TrkA C-terminal domain protein
NMELFEPI_00167 1.4e-178 S Oxidoreductase family, NAD-binding Rossmann fold
NMELFEPI_00168 8.1e-140
NMELFEPI_00169 1.4e-142
NMELFEPI_00170 2.4e-74 S PAS domain
NMELFEPI_00171 1.1e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NMELFEPI_00172 2.4e-46 S HicB_like antitoxin of bacterial toxin-antitoxin system
NMELFEPI_00173 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMELFEPI_00174 3.4e-71 2.4.1.83 GT2 S GtrA-like protein
NMELFEPI_00175 8e-179 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NMELFEPI_00176 1.2e-118
NMELFEPI_00177 1.2e-152 glcU U sugar transport
NMELFEPI_00178 2.2e-170 yqhA G Aldose 1-epimerase
NMELFEPI_00179 2.3e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NMELFEPI_00180 7.4e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NMELFEPI_00181 0.0 XK27_08315 M Sulfatase
NMELFEPI_00182 3.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMELFEPI_00184 2.9e-259 pepC 3.4.22.40 E aminopeptidase
NMELFEPI_00185 1.6e-120 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NMELFEPI_00186 3.3e-255 pepC 3.4.22.40 E aminopeptidase
NMELFEPI_00187 1.2e-32
NMELFEPI_00188 1.1e-75 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NMELFEPI_00189 2.7e-73 hsp O Belongs to the small heat shock protein (HSP20) family
NMELFEPI_00190 2.2e-292 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMELFEPI_00191 7.5e-83
NMELFEPI_00192 4.8e-249 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMELFEPI_00193 8.8e-130 yydK K UTRA
NMELFEPI_00194 2.4e-71 S Domain of unknown function (DUF3284)
NMELFEPI_00195 6.4e-303 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMELFEPI_00196 9.5e-135 gmuR K UTRA
NMELFEPI_00197 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
NMELFEPI_00198 1.6e-41
NMELFEPI_00199 2.6e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NMELFEPI_00200 1.7e-268 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMELFEPI_00201 1.1e-202 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMELFEPI_00202 0.0 L Transposase DDE domain
NMELFEPI_00203 3.8e-110 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMELFEPI_00204 1e-159 ypbG 2.7.1.2 GK ROK family
NMELFEPI_00205 1.8e-116
NMELFEPI_00207 1.2e-114 E Belongs to the SOS response-associated peptidase family
NMELFEPI_00208 1.2e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMELFEPI_00209 5.6e-91 comEB 3.5.4.12 F MafB19-like deaminase
NMELFEPI_00210 4e-99 S TPM domain
NMELFEPI_00211 1.1e-181 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NMELFEPI_00212 1.4e-242 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMELFEPI_00213 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMELFEPI_00214 3.6e-148 tatD L hydrolase, TatD family
NMELFEPI_00215 1.2e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NMELFEPI_00216 1.2e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NMELFEPI_00217 2.2e-35 veg S Biofilm formation stimulator VEG
NMELFEPI_00218 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NMELFEPI_00219 5e-217 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NMELFEPI_00220 2.6e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMELFEPI_00221 1.7e-176 yvdE K helix_turn _helix lactose operon repressor
NMELFEPI_00222 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
NMELFEPI_00223 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NMELFEPI_00224 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NMELFEPI_00225 7.6e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NMELFEPI_00226 9.8e-208 msmX P Belongs to the ABC transporter superfamily
NMELFEPI_00227 2.8e-216 malE G Bacterial extracellular solute-binding protein
NMELFEPI_00228 2.3e-251 malF P Binding-protein-dependent transport system inner membrane component
NMELFEPI_00229 1.6e-152 malG P ABC transporter permease
NMELFEPI_00230 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
NMELFEPI_00231 1.4e-264 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
NMELFEPI_00232 4.4e-68 S Domain of unknown function (DUF1934)
NMELFEPI_00233 2.5e-63 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NMELFEPI_00234 9e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NMELFEPI_00235 2.5e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMELFEPI_00236 1.1e-232 pbuX F xanthine permease
NMELFEPI_00237 9.9e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NMELFEPI_00238 1.4e-123 K Psort location CytoplasmicMembrane, score
NMELFEPI_00239 4.4e-299 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NMELFEPI_00240 9.4e-12
NMELFEPI_00241 9.8e-112 K transcriptional regulator
NMELFEPI_00242 2e-94 yxkA S Phosphatidylethanolamine-binding protein
NMELFEPI_00243 1.2e-147 K Helix-turn-helix
NMELFEPI_00244 3e-110 1.6.5.2 S NADPH-dependent FMN reductase
NMELFEPI_00245 3.9e-93 K Bacterial regulatory proteins, tetR family
NMELFEPI_00246 8.5e-56 yjdF S Protein of unknown function (DUF2992)
NMELFEPI_00247 8.2e-218 ywhK S Membrane
NMELFEPI_00248 2e-152 cylA V ABC transporter
NMELFEPI_00249 5.4e-137 cylB V ABC-2 type transporter
NMELFEPI_00250 1.1e-72 K LytTr DNA-binding domain
NMELFEPI_00251 4e-63 S Protein of unknown function (DUF3021)
NMELFEPI_00252 4.9e-82 XK27_09675 K Acetyltransferase (GNAT) domain
NMELFEPI_00253 2.4e-72 1.1.1.1 C nadph quinone reductase
NMELFEPI_00254 9.2e-48 1.1.1.1 C nadph quinone reductase
NMELFEPI_00255 1.1e-102 L PFAM Integrase catalytic region
NMELFEPI_00256 2.2e-40 L Helix-turn-helix domain
NMELFEPI_00257 8.9e-95
NMELFEPI_00258 5.7e-266 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NMELFEPI_00259 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NMELFEPI_00260 6e-187 yfdV S Membrane transport protein
NMELFEPI_00261 1.8e-28
NMELFEPI_00262 1.1e-66 S Putative adhesin
NMELFEPI_00263 2.1e-79
NMELFEPI_00264 1.1e-31 hxlR K Transcriptional regulator, HxlR family
NMELFEPI_00265 2.3e-78 XK27_02070 S Nitroreductase family
NMELFEPI_00266 1.7e-81 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NMELFEPI_00267 2e-43 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NMELFEPI_00268 2.6e-282 pipD E Dipeptidase
NMELFEPI_00269 1.2e-154 msmR K AraC-like ligand binding domain
NMELFEPI_00270 0.0 gph G Transporter
NMELFEPI_00271 0.0 rafA 3.2.1.22 G alpha-galactosidase
NMELFEPI_00272 4.6e-274 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NMELFEPI_00273 3.1e-226 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NMELFEPI_00274 1e-179 ABC-SBP S ABC transporter
NMELFEPI_00275 5.4e-140 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NMELFEPI_00276 1.7e-134 XK27_08845 S ABC transporter, ATP-binding protein
NMELFEPI_00277 1.3e-298 ybeC E amino acid
NMELFEPI_00278 1.4e-40 rpmE2 J Ribosomal protein L31
NMELFEPI_00279 2.3e-67 L COG3547 Transposase and inactivated derivatives
NMELFEPI_00280 5e-82 L Transposase
NMELFEPI_00281 6.3e-59 L Transposase
NMELFEPI_00282 2e-178 M domain protein
NMELFEPI_00283 6.7e-149 L COG3547 Transposase and inactivated derivatives
NMELFEPI_00284 1.9e-261 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NMELFEPI_00285 1.9e-267 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NMELFEPI_00286 8.5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NMELFEPI_00287 2.1e-213 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMELFEPI_00288 2.3e-122 S (CBS) domain
NMELFEPI_00289 3.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NMELFEPI_00290 1.3e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NMELFEPI_00291 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NMELFEPI_00292 5.4e-34 yabO J S4 domain protein
NMELFEPI_00293 4e-60 divIC D Septum formation initiator
NMELFEPI_00294 4.9e-60 yabR J S1 RNA binding domain
NMELFEPI_00295 2.5e-242 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NMELFEPI_00296 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NMELFEPI_00297 0.0 S membrane
NMELFEPI_00298 0.0 S membrane
NMELFEPI_00299 1.9e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NMELFEPI_00300 3.4e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMELFEPI_00301 1.7e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NMELFEPI_00302 1.6e-08
NMELFEPI_00304 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NMELFEPI_00305 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMELFEPI_00306 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMELFEPI_00307 8e-96 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NMELFEPI_00308 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NMELFEPI_00309 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NMELFEPI_00310 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NMELFEPI_00311 2.2e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
NMELFEPI_00312 4.8e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NMELFEPI_00313 1e-105 rplD J Forms part of the polypeptide exit tunnel
NMELFEPI_00314 1.7e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NMELFEPI_00315 2.3e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NMELFEPI_00316 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NMELFEPI_00317 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NMELFEPI_00318 1.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NMELFEPI_00319 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NMELFEPI_00320 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NMELFEPI_00321 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NMELFEPI_00322 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NMELFEPI_00323 1.1e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NMELFEPI_00324 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NMELFEPI_00325 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMELFEPI_00326 2.1e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NMELFEPI_00327 2.9e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NMELFEPI_00328 1.5e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NMELFEPI_00329 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NMELFEPI_00330 1.4e-23 rpmD J Ribosomal protein L30
NMELFEPI_00331 1.3e-70 rplO J Binds to the 23S rRNA
NMELFEPI_00332 4.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NMELFEPI_00333 1.3e-119 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NMELFEPI_00334 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NMELFEPI_00335 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NMELFEPI_00336 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NMELFEPI_00337 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NMELFEPI_00338 9.6e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMELFEPI_00339 7.4e-62 rplQ J Ribosomal protein L17
NMELFEPI_00340 6.5e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMELFEPI_00341 4.9e-162 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMELFEPI_00342 4.8e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMELFEPI_00343 8.7e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NMELFEPI_00344 5e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NMELFEPI_00345 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NMELFEPI_00346 0.0 LV site-specific DNA-methyltransferase (adenine-specific) activity
NMELFEPI_00347 9.5e-133 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMELFEPI_00348 5.3e-127 cobB K Sir2 family
NMELFEPI_00349 4.3e-115 GM NAD(P)H-binding
NMELFEPI_00350 2.1e-197 S membrane
NMELFEPI_00351 1.2e-98 K Transcriptional regulator C-terminal region
NMELFEPI_00352 2.1e-149 1.6.5.2 GM NmrA-like family
NMELFEPI_00353 1.9e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NMELFEPI_00354 2.5e-129 pgm3 G Belongs to the phosphoglycerate mutase family
NMELFEPI_00355 2.6e-52 K Transcriptional regulator, ArsR family
NMELFEPI_00356 1.1e-153 czcD P cation diffusion facilitator family transporter
NMELFEPI_00357 4.5e-39
NMELFEPI_00358 9.9e-12
NMELFEPI_00359 3.5e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NMELFEPI_00360 1.3e-184 S AAA domain
NMELFEPI_00361 1.2e-163 L Transposase
NMELFEPI_00362 3e-227 isp2 L Transposase
NMELFEPI_00363 2.9e-161 sprD D Domain of Unknown Function (DUF1542)
NMELFEPI_00364 0.0 sprD D Domain of Unknown Function (DUF1542)
NMELFEPI_00365 0.0 L Transposase
NMELFEPI_00366 2.2e-130 L Transposase DDE domain
NMELFEPI_00367 4e-120 L Transposase and inactivated derivatives, IS30 family
NMELFEPI_00368 8.9e-106 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
NMELFEPI_00369 4.5e-99 asp1 S Accessory Sec system protein Asp1
NMELFEPI_00370 1e-154 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
NMELFEPI_00371 6.2e-48 asp3 S Accessory Sec secretory system ASP3
NMELFEPI_00372 1.2e-271 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NMELFEPI_00373 4.5e-187 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NMELFEPI_00374 2.4e-144 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NMELFEPI_00376 5.2e-21 sraP UW this gene contains a nucleotide ambiguity which may be the result of a sequencing error
NMELFEPI_00377 1.7e-262 L Transposase IS66 family
NMELFEPI_00378 5.7e-33 S Transposase C of IS166 homeodomain
NMELFEPI_00379 7.4e-61 L PFAM IS66 Orf2 family protein
NMELFEPI_00380 1.4e-23
NMELFEPI_00381 7.5e-17 cpsJ S glycosyl transferase family 2
NMELFEPI_00382 5.3e-127 cpsJ S glycosyl transferase family 2
NMELFEPI_00383 2.1e-24 L Helix-turn-helix domain
NMELFEPI_00385 7.7e-101 L PFAM Integrase catalytic region
NMELFEPI_00386 4.9e-190 nss M transferase activity, transferring glycosyl groups
NMELFEPI_00387 2.8e-265 pepC 3.4.22.40 E Peptidase C1-like family
NMELFEPI_00388 9.9e-51 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NMELFEPI_00389 1.5e-77 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NMELFEPI_00390 7.3e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NMELFEPI_00391 5.4e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NMELFEPI_00392 1.5e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NMELFEPI_00393 1.3e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMELFEPI_00394 1.3e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NMELFEPI_00395 2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMELFEPI_00396 3.5e-89 yvrI K sigma factor activity
NMELFEPI_00397 1.7e-34
NMELFEPI_00398 5.1e-284 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NMELFEPI_00399 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NMELFEPI_00400 1.3e-227 G Major Facilitator Superfamily
NMELFEPI_00401 5.1e-190 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NMELFEPI_00402 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NMELFEPI_00403 3.4e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NMELFEPI_00404 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
NMELFEPI_00405 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NMELFEPI_00406 3.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NMELFEPI_00407 4.6e-109 glnP P ABC transporter permease
NMELFEPI_00408 3.9e-116 glnQ 3.6.3.21 E ABC transporter
NMELFEPI_00409 2.1e-143 aatB ET ABC transporter substrate-binding protein
NMELFEPI_00410 4.2e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NMELFEPI_00411 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NMELFEPI_00412 2.3e-127 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
NMELFEPI_00413 1e-31
NMELFEPI_00414 2.3e-110 rsmC 2.1.1.172 J Methyltransferase
NMELFEPI_00415 3.6e-22
NMELFEPI_00416 3e-84 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NMELFEPI_00417 5e-311 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMELFEPI_00418 3.5e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NMELFEPI_00419 6.9e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NMELFEPI_00420 9e-26 S Protein of unknown function (DUF2508)
NMELFEPI_00421 3.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NMELFEPI_00422 5e-51 yaaQ S Cyclic-di-AMP receptor
NMELFEPI_00423 3.1e-153 holB 2.7.7.7 L DNA polymerase III
NMELFEPI_00424 4.4e-58 yabA L Involved in initiation control of chromosome replication
NMELFEPI_00425 3.7e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NMELFEPI_00426 1.9e-138 fat 3.1.2.21 I Acyl-ACP thioesterase
NMELFEPI_00427 1.3e-85 folT S ECF transporter, substrate-specific component
NMELFEPI_00428 1.2e-129 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NMELFEPI_00429 1.1e-95 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NMELFEPI_00430 4e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NMELFEPI_00431 3e-105
NMELFEPI_00432 1.5e-242 clcA P chloride
NMELFEPI_00433 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NMELFEPI_00434 1.6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NMELFEPI_00435 5.8e-244 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NMELFEPI_00436 7e-125 L oxidized base lesion DNA N-glycosylase activity
NMELFEPI_00437 4.6e-71 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
NMELFEPI_00438 1.1e-47 L bacterial-type proximal promoter sequence-specific DNA binding
NMELFEPI_00439 5.7e-17 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NMELFEPI_00440 5.4e-228 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NMELFEPI_00441 2.1e-66 K Helix-turn-helix XRE-family like proteins
NMELFEPI_00442 1.9e-146 G Transmembrane secretion effector
NMELFEPI_00443 2.5e-24 uup S ABC transporter, ATP-binding protein
NMELFEPI_00444 2e-149 K Helix-turn-helix XRE-family like proteins
NMELFEPI_00445 1.3e-76
NMELFEPI_00446 2.4e-242 G Bacterial extracellular solute-binding protein
NMELFEPI_00447 0.0 uup S ABC transporter, ATP-binding protein
NMELFEPI_00448 2.8e-249 L transposase, IS605 OrfB family
NMELFEPI_00449 6.4e-84 tlpA2 L Transposase IS200 like
NMELFEPI_00450 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NMELFEPI_00451 4.4e-103 yvdD 3.2.2.10 S Belongs to the LOG family
NMELFEPI_00452 1.3e-48 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NMELFEPI_00453 2.7e-79 XK27_02470 K LytTr DNA-binding domain
NMELFEPI_00454 4e-120 liaI S membrane
NMELFEPI_00455 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NMELFEPI_00456 1.8e-295 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NMELFEPI_00457 1.4e-57
NMELFEPI_00458 2e-30
NMELFEPI_00459 0.0 nisT V ABC transporter
NMELFEPI_00460 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NMELFEPI_00461 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NMELFEPI_00462 9.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NMELFEPI_00463 4.3e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NMELFEPI_00464 1.3e-38 yajC U Preprotein translocase
NMELFEPI_00465 1.2e-282 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NMELFEPI_00466 3.2e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMELFEPI_00467 1.9e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NMELFEPI_00468 3.4e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NMELFEPI_00469 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NMELFEPI_00470 2.6e-42 yrzL S Belongs to the UPF0297 family
NMELFEPI_00471 9.8e-71 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NMELFEPI_00472 4.2e-39 yrzB S Belongs to the UPF0473 family
NMELFEPI_00473 3.9e-93 cvpA S Colicin V production protein
NMELFEPI_00474 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NMELFEPI_00475 1.1e-52 trxA O Belongs to the thioredoxin family
NMELFEPI_00476 2.2e-174 L Psort location Cytoplasmic, score
NMELFEPI_00477 3.2e-68 yslB S Protein of unknown function (DUF2507)
NMELFEPI_00479 8.7e-41 L Replication initiation factor
NMELFEPI_00486 1.8e-08 S Helix-turn-helix domain
NMELFEPI_00487 2.3e-12 K Transcriptional
NMELFEPI_00488 4.3e-63 sip L Belongs to the 'phage' integrase family
NMELFEPI_00489 3.2e-144 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NMELFEPI_00490 4.5e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NMELFEPI_00491 3.6e-216 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NMELFEPI_00492 1.3e-138 ykuT M mechanosensitive ion channel
NMELFEPI_00493 1.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NMELFEPI_00494 9.6e-50
NMELFEPI_00495 6.1e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NMELFEPI_00496 9.8e-175 ccpA K catabolite control protein A
NMELFEPI_00497 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
NMELFEPI_00498 4e-275 pepV 3.5.1.18 E dipeptidase PepV
NMELFEPI_00499 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NMELFEPI_00500 1.3e-54
NMELFEPI_00501 2.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NMELFEPI_00502 1.3e-91 yutD S Protein of unknown function (DUF1027)
NMELFEPI_00503 1.4e-147 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NMELFEPI_00504 1.1e-102 S Protein of unknown function (DUF1461)
NMELFEPI_00505 6.1e-117 dedA S SNARE-like domain protein
NMELFEPI_00506 1.9e-175 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NMELFEPI_00507 3.2e-62 yugI 5.3.1.9 J general stress protein
NMELFEPI_00508 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
NMELFEPI_00513 2.4e-215 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NMELFEPI_00514 2e-253 qacA EGP Major facilitator Superfamily
NMELFEPI_00515 1.4e-113 3.6.1.27 I Acid phosphatase homologues
NMELFEPI_00516 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMELFEPI_00517 4.7e-299 ytgP S Polysaccharide biosynthesis protein
NMELFEPI_00518 4.1e-217 MA20_36090 S Protein of unknown function (DUF2974)
NMELFEPI_00519 2.8e-134
NMELFEPI_00520 1.5e-144 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NMELFEPI_00521 1.1e-167 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NMELFEPI_00522 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NMELFEPI_00523 1.9e-172 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NMELFEPI_00524 2.7e-46
NMELFEPI_00526 1.5e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
NMELFEPI_00527 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NMELFEPI_00528 3e-127 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
NMELFEPI_00529 1.7e-111 ylbE GM NAD(P)H-binding
NMELFEPI_00530 1.1e-253 L transposase, IS605 OrfB family
NMELFEPI_00531 2e-85 tlpA2 L Transposase IS200 like
NMELFEPI_00532 2.6e-82 yebR 1.8.4.14 T GAF domain-containing protein
NMELFEPI_00533 2.1e-32 yfeO P Voltage gated chloride channel
NMELFEPI_00534 8.4e-66 yfeO P Voltage gated chloride channel
NMELFEPI_00535 8.5e-96 yfeO P Voltage gated chloride channel
NMELFEPI_00536 1.5e-191 S Bacteriocin helveticin-J
NMELFEPI_00537 7e-101 tag 3.2.2.20 L glycosylase
NMELFEPI_00538 8.4e-160 mleP3 S Membrane transport protein
NMELFEPI_00539 1.7e-137 S CAAX amino terminal protease
NMELFEPI_00540 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NMELFEPI_00541 2.7e-253 emrY EGP Major facilitator Superfamily
NMELFEPI_00542 1.7e-174 L Psort location Cytoplasmic, score
NMELFEPI_00543 4.8e-255 emrY EGP Major facilitator Superfamily
NMELFEPI_00544 1.8e-69
NMELFEPI_00545 2e-86 yxdD K Bacterial regulatory proteins, tetR family
NMELFEPI_00546 0.0 4.2.1.53 S Myosin-crossreactive antigen
NMELFEPI_00547 6.7e-134 ybfG M peptidoglycan-binding domain-containing protein
NMELFEPI_00548 3.2e-25 3.2.1.17 M peptidoglycan-binding domain-containing protein
NMELFEPI_00550 1.8e-16
NMELFEPI_00551 1e-75 2.3.1.128 K acetyltransferase
NMELFEPI_00552 5e-28 S PFAM Archaeal ATPase
NMELFEPI_00553 6.3e-124 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NMELFEPI_00554 3.1e-240 pyrP F Permease
NMELFEPI_00555 3e-131 lacR K DeoR C terminal sensor domain
NMELFEPI_00556 5.1e-72 lacA 5.3.1.26 G Ribose/Galactose Isomerase
NMELFEPI_00557 1.6e-105 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
NMELFEPI_00558 1.9e-131 lacT K CAT RNA binding domain
NMELFEPI_00559 6.9e-54 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
NMELFEPI_00560 1e-299 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
NMELFEPI_00561 1.4e-278 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
NMELFEPI_00562 5.8e-158 K LysR family
NMELFEPI_00563 0.0 1.3.5.4 C FMN_bind
NMELFEPI_00564 1.4e-254 P Sodium:sulfate symporter transmembrane region
NMELFEPI_00565 8.8e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
NMELFEPI_00566 2.8e-111 3.6.1.27 I Acid phosphatase homologues
NMELFEPI_00567 7.9e-284 E Phospholipase B
NMELFEPI_00568 3.6e-265 pepC 3.4.22.40 E Peptidase C1-like family
NMELFEPI_00569 4e-271 gadC E Contains amino acid permease domain
NMELFEPI_00570 1.2e-36 pipD E Peptidase family C69
NMELFEPI_00571 3.4e-185 pipD E Peptidase family C69
NMELFEPI_00572 4e-264 pepC 3.4.22.40 E Peptidase C1-like family
NMELFEPI_00573 2.3e-306 gadC E Contains amino acid permease domain
NMELFEPI_00574 2.1e-227 L COG3547 Transposase and inactivated derivatives
NMELFEPI_00575 3.2e-248 yagE E amino acid
NMELFEPI_00576 2.5e-217 mdtG EGP Major facilitator Superfamily
NMELFEPI_00577 3.2e-30
NMELFEPI_00578 2.3e-69 K helix_turn_helix multiple antibiotic resistance protein
NMELFEPI_00579 7.7e-79
NMELFEPI_00580 2.1e-227 L COG3547 Transposase and inactivated derivatives
NMELFEPI_00581 5.1e-209 pepA E M42 glutamyl aminopeptidase
NMELFEPI_00583 7.8e-112 ybbL S ABC transporter, ATP-binding protein
NMELFEPI_00584 2.1e-129 ybbM S Uncharacterised protein family (UPF0014)
NMELFEPI_00585 8.4e-211 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
NMELFEPI_00586 3.9e-89 lacA 3.2.1.23 G -beta-galactosidase
NMELFEPI_00587 4.1e-68 lacA 3.2.1.23 G -beta-galactosidase
NMELFEPI_00588 2.1e-41 lacA 3.2.1.23 G -beta-galactosidase
NMELFEPI_00589 2.5e-283 dtpT U amino acid peptide transporter
NMELFEPI_00590 4.2e-280 pipD E Peptidase family C69
NMELFEPI_00591 1.2e-217 naiP EGP Major facilitator Superfamily
NMELFEPI_00592 1.3e-154 S Alpha beta hydrolase
NMELFEPI_00593 3e-67 K Transcriptional regulator, MarR family
NMELFEPI_00594 1.3e-299 XK27_09600 V ABC transporter, ATP-binding protein
NMELFEPI_00595 0.0 V ABC transporter transmembrane region
NMELFEPI_00596 1.9e-147 glnH ET ABC transporter
NMELFEPI_00597 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NMELFEPI_00598 3.1e-150 glnH ET ABC transporter
NMELFEPI_00599 2.4e-110 gluC P ABC transporter permease
NMELFEPI_00600 5.7e-107 glnP P ABC transporter permease
NMELFEPI_00601 2.1e-64
NMELFEPI_00602 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NMELFEPI_00603 1.1e-130 treR K UTRA
NMELFEPI_00604 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMELFEPI_00605 4.9e-76 S Putative adhesin
NMELFEPI_00607 3.2e-279 L Transposase
NMELFEPI_00608 8.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NMELFEPI_00610 1.2e-21 2.7.13.3 T GHKL domain
NMELFEPI_00611 1.6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
NMELFEPI_00612 2.1e-186 2.7.13.3 T GHKL domain
NMELFEPI_00613 8.2e-140 K LytTr DNA-binding domain
NMELFEPI_00614 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NMELFEPI_00615 7.3e-101 M Transport protein ComB
NMELFEPI_00617 1.3e-45 S Enterocin A Immunity
NMELFEPI_00618 1.3e-224 S CAAX protease self-immunity
NMELFEPI_00622 1.8e-53 S Enterocin A Immunity
NMELFEPI_00624 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
NMELFEPI_00625 4.5e-160 rssA S Phospholipase, patatin family
NMELFEPI_00626 1.3e-255 glnPH2 P ABC transporter permease
NMELFEPI_00627 2.1e-129 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NMELFEPI_00628 2.8e-96 K Acetyltransferase (GNAT) domain
NMELFEPI_00629 2.1e-160 pstS P Phosphate
NMELFEPI_00630 1.2e-161 pstC P probably responsible for the translocation of the substrate across the membrane
NMELFEPI_00631 2.4e-156 pstA P Phosphate transport system permease protein PstA
NMELFEPI_00632 6.3e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMELFEPI_00633 7.8e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMELFEPI_00634 1.9e-108 phoU P Plays a role in the regulation of phosphate uptake
NMELFEPI_00635 2.8e-60 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMELFEPI_00636 5.1e-279 S C4-dicarboxylate anaerobic carrier
NMELFEPI_00637 3.8e-84 dps P Belongs to the Dps family
NMELFEPI_00638 2.7e-158 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NMELFEPI_00639 2.2e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NMELFEPI_00640 1.2e-174 rihB 3.2.2.1 F Nucleoside
NMELFEPI_00641 4e-133 gntR K UbiC transcription regulator-associated domain protein
NMELFEPI_00642 7e-53 S Enterocin A Immunity
NMELFEPI_00643 4.7e-140 glcR K DeoR C terminal sensor domain
NMELFEPI_00644 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NMELFEPI_00645 2.6e-115 C nitroreductase
NMELFEPI_00646 5.5e-124
NMELFEPI_00647 1.1e-237 yhdP S Transporter associated domain
NMELFEPI_00648 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NMELFEPI_00649 1.8e-232 potE E amino acid
NMELFEPI_00650 5.8e-137 M Glycosyl hydrolases family 25
NMELFEPI_00651 3.5e-206 yfmL 3.6.4.13 L DEAD DEAH box helicase
NMELFEPI_00652 3.9e-251 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMELFEPI_00654 2.2e-106 L Belongs to the 'phage' integrase family
NMELFEPI_00655 1.2e-48
NMELFEPI_00656 4.6e-73 S Pfam:Peptidase_M78
NMELFEPI_00657 1.6e-55 ansR 3.4.21.88 K Cro/C1-type HTH DNA-binding domain
NMELFEPI_00658 7.5e-29 K Helix-turn-helix XRE-family like proteins
NMELFEPI_00659 7.3e-106 K Phage antirepressor protein
NMELFEPI_00661 1.5e-25
NMELFEPI_00664 1.2e-11
NMELFEPI_00665 4.4e-26
NMELFEPI_00666 6.3e-34 S Siphovirus Gp157
NMELFEPI_00667 2.2e-21 S ERF superfamily
NMELFEPI_00668 5.1e-46 S calcium ion binding
NMELFEPI_00669 7.4e-64 S IstB-like ATP binding protein
NMELFEPI_00675 6e-58 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
NMELFEPI_00676 1.1e-10
NMELFEPI_00678 1.5e-09
NMELFEPI_00680 6.2e-58 gepA K Protein of unknown function (DUF4065)
NMELFEPI_00681 3.2e-29
NMELFEPI_00682 8.4e-80 S Terminase small subunit
NMELFEPI_00683 2.2e-224 S DNA packaging
NMELFEPI_00684 2.2e-252 S Phage portal protein, SPP1 Gp6-like
NMELFEPI_00685 2.5e-182 S Phage Mu protein F like protein
NMELFEPI_00687 3.1e-61 S Phage minor structural protein GP20
NMELFEPI_00688 3.5e-186
NMELFEPI_00689 2.8e-64 S Phage gp6-like head-tail connector protein
NMELFEPI_00690 1.6e-61
NMELFEPI_00691 1.7e-75
NMELFEPI_00692 5.3e-61
NMELFEPI_00693 6.6e-17
NMELFEPI_00694 5.7e-226 S Phage tail sheath protein
NMELFEPI_00695 2.4e-83 S Protein of unknown function (DUF2001)
NMELFEPI_00696 4.9e-67 S Pfam:Phage_TAC_5
NMELFEPI_00697 5.5e-201 S phage tail tape measure protein
NMELFEPI_00698 4.1e-108 ygaU GH23 S protein containing LysM domain
NMELFEPI_00699 3.9e-198 S N-acetylmuramoyl-L-alanine amidase activity
NMELFEPI_00700 1.7e-55 S Protein of unknown function (DUF2577)
NMELFEPI_00701 2.5e-59 S Protein of unknown function (DUF2634)
NMELFEPI_00702 1.8e-204 S Baseplate J-like protein
NMELFEPI_00703 4.1e-93 S Uncharacterized protein conserved in bacteria (DUF2313)
NMELFEPI_00704 2.6e-303 S N-acetylmuramoyl-L-alanine amidase activity
NMELFEPI_00705 3.2e-73
NMELFEPI_00707 2.6e-60
NMELFEPI_00708 4.7e-42
NMELFEPI_00709 2.1e-62 S Pfam:Phage_holin_6_1
NMELFEPI_00710 2.8e-184 S N-acetylmuramoyl-L-alanine amidase activity
NMELFEPI_00713 5.5e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NMELFEPI_00714 1.6e-88 gtcA S Teichoic acid glycosylation protein
NMELFEPI_00715 2.5e-77 fld C Flavodoxin
NMELFEPI_00716 1.9e-160 map 3.4.11.18 E Methionine Aminopeptidase
NMELFEPI_00717 1e-162 yihY S Belongs to the UPF0761 family
NMELFEPI_00718 1.2e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NMELFEPI_00719 1.8e-181 E ABC transporter, ATP-binding protein
NMELFEPI_00720 1.3e-285 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NMELFEPI_00721 5.6e-68 O OsmC-like protein
NMELFEPI_00722 2.8e-163 ltrA S Bacterial low temperature requirement A protein (LtrA)
NMELFEPI_00723 3.5e-114 2.7.6.5 T Region found in RelA / SpoT proteins
NMELFEPI_00724 1.8e-116 K response regulator
NMELFEPI_00725 1.8e-226 sptS 2.7.13.3 T Histidine kinase
NMELFEPI_00726 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NMELFEPI_00727 0.0 pepN 3.4.11.2 E aminopeptidase
NMELFEPI_00728 8.7e-139 S haloacid dehalogenase-like hydrolase
NMELFEPI_00730 6.9e-287 V ABC transporter transmembrane region
NMELFEPI_00731 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NMELFEPI_00732 1.8e-69
NMELFEPI_00733 3.2e-107 fic D Fic/DOC family
NMELFEPI_00734 8.1e-140 ppm1 GT2 M Glycosyl transferase family 2
NMELFEPI_00735 1.2e-278 L Transposase
NMELFEPI_00736 2.4e-93 S Domain of unknown function (DUF4811)
NMELFEPI_00737 1.4e-265 lmrB EGP Major facilitator Superfamily
NMELFEPI_00738 1.9e-77 K MerR HTH family regulatory protein
NMELFEPI_00739 1.2e-278 L Transposase
NMELFEPI_00740 0.0 oppA E ABC transporter substrate-binding protein
NMELFEPI_00741 2.1e-227 L COG3547 Transposase and inactivated derivatives
NMELFEPI_00742 1.6e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
NMELFEPI_00743 2e-255 pepC 3.4.22.40 E Peptidase C1-like family
NMELFEPI_00744 1.6e-75 M domain protein
NMELFEPI_00745 1.9e-170 I Carboxylesterase family
NMELFEPI_00746 6.9e-295 S Predicted membrane protein (DUF2207)
NMELFEPI_00747 1.6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
NMELFEPI_00748 4.5e-120 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NMELFEPI_00749 6.3e-54
NMELFEPI_00750 1.1e-142 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NMELFEPI_00751 7.6e-92 S ECF-type riboflavin transporter, S component
NMELFEPI_00752 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NMELFEPI_00753 6.3e-64
NMELFEPI_00754 3.5e-12
NMELFEPI_00755 1.5e-215 S Uncharacterized protein conserved in bacteria (DUF2325)
NMELFEPI_00756 2.9e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMELFEPI_00757 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
NMELFEPI_00758 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NMELFEPI_00759 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NMELFEPI_00760 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NMELFEPI_00761 1.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NMELFEPI_00762 8.2e-73 yqhY S Asp23 family, cell envelope-related function
NMELFEPI_00763 3.6e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NMELFEPI_00764 3.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NMELFEPI_00765 8.2e-249 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMELFEPI_00766 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMELFEPI_00767 3.3e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NMELFEPI_00768 4.6e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NMELFEPI_00769 2e-292 recN L May be involved in recombinational repair of damaged DNA
NMELFEPI_00770 1e-47
NMELFEPI_00771 7.3e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NMELFEPI_00772 2.3e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NMELFEPI_00773 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMELFEPI_00774 9.3e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NMELFEPI_00775 6.1e-241 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NMELFEPI_00776 7.8e-140 stp 3.1.3.16 T phosphatase
NMELFEPI_00777 0.0 KLT serine threonine protein kinase
NMELFEPI_00778 4.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NMELFEPI_00779 4.1e-121 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NMELFEPI_00780 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
NMELFEPI_00781 1.2e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NMELFEPI_00782 1.4e-57 asp S Asp23 family, cell envelope-related function
NMELFEPI_00783 3.6e-307 yloV S DAK2 domain fusion protein YloV
NMELFEPI_00784 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NMELFEPI_00785 7.1e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NMELFEPI_00786 4.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMELFEPI_00787 3.1e-192 oppD P Belongs to the ABC transporter superfamily
NMELFEPI_00788 4.6e-177 oppF P Belongs to the ABC transporter superfamily
NMELFEPI_00789 1.6e-177 oppB P ABC transporter permease
NMELFEPI_00790 2e-161 oppC P Binding-protein-dependent transport system inner membrane component
NMELFEPI_00791 0.0 oppA E ABC transporter substrate-binding protein
NMELFEPI_00792 0.0 oppA E ABC transporter substrate-binding protein
NMELFEPI_00793 2e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NMELFEPI_00794 0.0 smc D Required for chromosome condensation and partitioning
NMELFEPI_00795 2.4e-165 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NMELFEPI_00796 7.5e-285 pipD E Dipeptidase
NMELFEPI_00797 9e-61 L COG2963 Transposase and inactivated derivatives
NMELFEPI_00798 5.2e-25 L COG2963 Transposase and inactivated derivatives
NMELFEPI_00800 1.4e-41 L transposase activity
NMELFEPI_00801 1.5e-17 UW LPXTG-motif cell wall anchor domain protein
NMELFEPI_00802 9e-203 L COG2826 Transposase and inactivated derivatives, IS30 family
NMELFEPI_00803 4.1e-222 UW LPXTG-motif cell wall anchor domain protein
NMELFEPI_00804 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NMELFEPI_00805 2.5e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NMELFEPI_00806 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NMELFEPI_00807 3.1e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NMELFEPI_00808 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NMELFEPI_00809 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NMELFEPI_00810 1.8e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NMELFEPI_00811 1.1e-69 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NMELFEPI_00812 8.1e-114 ung2 3.2.2.27 L Uracil-DNA glycosylase
NMELFEPI_00813 7.9e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NMELFEPI_00814 1.6e-33 ynzC S UPF0291 protein
NMELFEPI_00815 1.9e-30 yneF S Uncharacterised protein family (UPF0154)
NMELFEPI_00816 0.0 mdlA V ABC transporter
NMELFEPI_00817 2.3e-283 mdlB V ABC transporter
NMELFEPI_00818 3e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NMELFEPI_00819 2.6e-117 plsC 2.3.1.51 I Acyltransferase
NMELFEPI_00820 2.6e-183 yabB 2.1.1.223 L Methyltransferase small domain
NMELFEPI_00821 5.8e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
NMELFEPI_00822 9.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NMELFEPI_00823 1.8e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NMELFEPI_00824 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NMELFEPI_00825 8.5e-136 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NMELFEPI_00826 1.5e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NMELFEPI_00827 9.3e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NMELFEPI_00828 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NMELFEPI_00829 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMELFEPI_00830 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
NMELFEPI_00831 9.4e-220 nusA K Participates in both transcription termination and antitermination
NMELFEPI_00832 1.5e-46 ylxR K Protein of unknown function (DUF448)
NMELFEPI_00833 7.1e-47 rplGA J ribosomal protein
NMELFEPI_00834 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NMELFEPI_00835 3.5e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NMELFEPI_00836 7.5e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NMELFEPI_00837 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NMELFEPI_00838 1.9e-278 lsa S ABC transporter
NMELFEPI_00839 5.7e-96 S GyrI-like small molecule binding domain
NMELFEPI_00840 2.5e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NMELFEPI_00841 3.8e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NMELFEPI_00842 0.0 dnaK O Heat shock 70 kDa protein
NMELFEPI_00843 9e-172 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NMELFEPI_00844 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NMELFEPI_00845 3.9e-122 srtA 3.4.22.70 M sortase family
NMELFEPI_00846 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NMELFEPI_00847 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NMELFEPI_00848 1.5e-275 yjeM E Amino Acid
NMELFEPI_00849 8.2e-46 L Helix-turn-helix domain
NMELFEPI_00850 1.2e-96 L PFAM Integrase catalytic region
NMELFEPI_00851 4.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMELFEPI_00852 1.4e-186 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NMELFEPI_00853 2.5e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NMELFEPI_00854 6.6e-251 G Major Facilitator
NMELFEPI_00855 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
NMELFEPI_00856 4.5e-152 lysR5 K LysR substrate binding domain
NMELFEPI_00859 2.2e-102 3.6.1.27 I Acid phosphatase homologues
NMELFEPI_00860 3.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NMELFEPI_00861 3.7e-18 S Sugar efflux transporter for intercellular exchange
NMELFEPI_00862 2.5e-305 ybiT S ABC transporter, ATP-binding protein
NMELFEPI_00863 2e-244 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMELFEPI_00864 1.4e-181 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NMELFEPI_00865 2.3e-48 K Helix-turn-helix domain
NMELFEPI_00866 2.2e-135 F DNA/RNA non-specific endonuclease
NMELFEPI_00867 2.3e-45 L nuclease
NMELFEPI_00868 5.1e-156 metQ1 P Belongs to the nlpA lipoprotein family
NMELFEPI_00869 1e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NMELFEPI_00870 1.4e-66 metI P ABC transporter permease
NMELFEPI_00871 3.4e-266 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NMELFEPI_00872 2.1e-244 frdC 1.3.5.4 C FAD binding domain
NMELFEPI_00873 7e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NMELFEPI_00874 1.8e-243 yjjP S Putative threonine/serine exporter
NMELFEPI_00875 9e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
NMELFEPI_00876 0.0 aha1 P E1-E2 ATPase
NMELFEPI_00877 6.3e-307 S Bacterial membrane protein, YfhO
NMELFEPI_00878 2.4e-24 S Bacterial membrane protein, YfhO
NMELFEPI_00879 4.3e-235 S Bacterial membrane protein, YfhO
NMELFEPI_00880 2e-67 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NMELFEPI_00881 4.1e-170 prmA J Ribosomal protein L11 methyltransferase
NMELFEPI_00882 2.4e-65
NMELFEPI_00883 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NMELFEPI_00884 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NMELFEPI_00885 6.2e-246 hisS 6.1.1.21 J histidyl-tRNA synthetase
NMELFEPI_00886 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NMELFEPI_00887 1.2e-222 patA 2.6.1.1 E Aminotransferase
NMELFEPI_00888 4.3e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NMELFEPI_00889 9.3e-141 E GDSL-like Lipase/Acylhydrolase family
NMELFEPI_00891 2.1e-224 L Belongs to the 'phage' integrase family
NMELFEPI_00894 5.5e-37 S Domain of unknown function (DUF4393)
NMELFEPI_00895 1.9e-40
NMELFEPI_00897 2.4e-14
NMELFEPI_00900 5.7e-22
NMELFEPI_00902 1.1e-45 E Zn peptidase
NMELFEPI_00903 5e-70 2.6.1.2, 2.6.1.66 K Helix-turn-helix XRE-family like proteins
NMELFEPI_00904 2.3e-31 K Protein of unknown function (DUF739)
NMELFEPI_00905 7e-99 K ORF6N domain
NMELFEPI_00906 1.1e-30
NMELFEPI_00915 1.1e-31 L Psort location Cytoplasmic, score
NMELFEPI_00916 8.3e-23 S sequence-specific DNA binding
NMELFEPI_00925 3.9e-84 arpU S Phage transcriptional regulator, ArpU family
NMELFEPI_00926 1.4e-76 S HNH endonuclease
NMELFEPI_00927 1.6e-66 L Phage terminase, small subunit
NMELFEPI_00931 8.5e-228 S Phage Terminase
NMELFEPI_00933 2e-169 S Phage portal protein
NMELFEPI_00934 1.1e-98 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NMELFEPI_00935 6.2e-176 S peptidase activity
NMELFEPI_00936 8.7e-39 S Phage gp6-like head-tail connector protein
NMELFEPI_00937 1.5e-08 S Phage head-tail joining protein
NMELFEPI_00938 6.9e-09 S Bacteriophage HK97-gp10, putative tail-component
NMELFEPI_00940 2.7e-08 S Pfam:Phage_TTP_1
NMELFEPI_00943 0.0 M Phage tail tape measure protein TP901
NMELFEPI_00944 2.5e-98 S Phage tail protein
NMELFEPI_00945 1.7e-138 S Phage minor structural protein
NMELFEPI_00947 5e-88 cotH M CotH kinase protein
NMELFEPI_00948 1.7e-45
NMELFEPI_00951 1.5e-108 lysA2 M Glycosyl hydrolases family 25
NMELFEPI_00952 3.6e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMELFEPI_00953 2.2e-154 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMELFEPI_00954 7.1e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NMELFEPI_00955 1.1e-153 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NMELFEPI_00956 1.2e-52 S Iron-sulfur cluster assembly protein
NMELFEPI_00957 8.6e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NMELFEPI_00958 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NMELFEPI_00959 2.9e-33 yqeY S YqeY-like protein
NMELFEPI_00960 4.7e-174 phoH T phosphate starvation-inducible protein PhoH
NMELFEPI_00961 1.5e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NMELFEPI_00962 4.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NMELFEPI_00963 1.5e-135 recO L Involved in DNA repair and RecF pathway recombination
NMELFEPI_00964 2.7e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NMELFEPI_00965 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NMELFEPI_00966 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NMELFEPI_00967 1.1e-198 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NMELFEPI_00968 8.4e-83
NMELFEPI_00969 2.1e-227 L COG3547 Transposase and inactivated derivatives
NMELFEPI_00970 2.6e-301 L Helicase C-terminal domain protein
NMELFEPI_00971 6.3e-66 S Psort location Cytoplasmic, score 8.87
NMELFEPI_00972 0.0 tetP J elongation factor G
NMELFEPI_00973 1.9e-89 XK26_06155 K Psort location Cytoplasmic, score
NMELFEPI_00974 4.6e-73 K Psort location Cytoplasmic, score 8.87
NMELFEPI_00975 1.5e-74
NMELFEPI_00976 2.4e-192 recA L Psort location Cytoplasmic, score 8.87
NMELFEPI_00977 2.1e-227 L COG3547 Transposase and inactivated derivatives
NMELFEPI_00978 2.9e-114 papP P ABC transporter, permease protein
NMELFEPI_00979 1.5e-105 P ABC transporter permease
NMELFEPI_00980 2.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NMELFEPI_00981 1.2e-141 cjaA ET ABC transporter substrate-binding protein
NMELFEPI_00982 7.1e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
NMELFEPI_00983 6.1e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NMELFEPI_00984 6e-246 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NMELFEPI_00985 3.6e-58 yvoA_1 K Transcriptional regulator, GntR family
NMELFEPI_00986 7.3e-124 skfE V ATPases associated with a variety of cellular activities
NMELFEPI_00987 1.6e-138
NMELFEPI_00988 1.1e-137
NMELFEPI_00989 1.4e-21
NMELFEPI_00990 1.1e-101 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NMELFEPI_00991 8.9e-133
NMELFEPI_00992 6.3e-174
NMELFEPI_00993 3.2e-264 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
NMELFEPI_00994 2.9e-248 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMELFEPI_00995 2.1e-49 ybjQ S Belongs to the UPF0145 family
NMELFEPI_00996 1.1e-97 XK27_05540 S DUF218 domain
NMELFEPI_00997 4.6e-58 XK27_05540 S DUF218 domain
NMELFEPI_00998 1.4e-147 yxeH S hydrolase
NMELFEPI_00999 3.4e-302 I Protein of unknown function (DUF2974)
NMELFEPI_01000 1.2e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NMELFEPI_01001 3.8e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NMELFEPI_01002 1.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NMELFEPI_01003 2.5e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NMELFEPI_01004 3.1e-178 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NMELFEPI_01005 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NMELFEPI_01006 3.3e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NMELFEPI_01007 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NMELFEPI_01008 2.8e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NMELFEPI_01009 5.9e-105 pncA Q Isochorismatase family
NMELFEPI_01010 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NMELFEPI_01011 2.1e-205 M Glycosyl transferases group 1
NMELFEPI_01012 7.7e-107 alkD L DNA alkylation repair enzyme
NMELFEPI_01013 6.2e-115 XK27_06785 V ABC transporter, ATP-binding protein
NMELFEPI_01014 0.0 XK27_06780 V ABC transporter permease
NMELFEPI_01015 0.0 pepO 3.4.24.71 O Peptidase family M13
NMELFEPI_01016 1.3e-114 drgA C nitroreductase
NMELFEPI_01017 2.3e-71 S SnoaL-like domain
NMELFEPI_01018 2.8e-09 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
NMELFEPI_01019 9.1e-46 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
NMELFEPI_01020 7.4e-203 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NMELFEPI_01021 5.7e-10 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NMELFEPI_01022 7.8e-136 qmcA O prohibitin homologues
NMELFEPI_01023 4.4e-178 V (ABC) transporter
NMELFEPI_01024 5.4e-292 V ABC-type multidrug transport system, ATPase and permease components
NMELFEPI_01025 8.6e-240 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NMELFEPI_01026 1.6e-203 yhjX P Major Facilitator Superfamily
NMELFEPI_01027 2.1e-77 C nitroreductase
NMELFEPI_01028 5.4e-276 V ABC transporter transmembrane region
NMELFEPI_01029 2.3e-48
NMELFEPI_01030 1e-31 S endonuclease activity
NMELFEPI_01031 9.4e-43
NMELFEPI_01032 1.4e-106 speG J Acetyltransferase (GNAT) domain
NMELFEPI_01033 5.9e-66
NMELFEPI_01034 2e-77
NMELFEPI_01035 1.5e-77 K Acetyltransferase (GNAT) domain
NMELFEPI_01036 1.4e-83 FG HIT domain
NMELFEPI_01037 5.2e-47 S MazG-like family
NMELFEPI_01038 1.5e-59
NMELFEPI_01039 1.3e-121 3.1.3.48 T Tyrosine phosphatase family
NMELFEPI_01040 2.9e-42
NMELFEPI_01041 2.5e-255 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMELFEPI_01042 1.6e-137 aroD S Serine hydrolase (FSH1)
NMELFEPI_01043 7.8e-11 rimL J Acetyltransferase (GNAT) domain
NMELFEPI_01044 1.9e-53 rimL J Acetyltransferase (GNAT) domain
NMELFEPI_01045 1.9e-86 2.3.1.57 K Acetyltransferase (GNAT) family
NMELFEPI_01046 1.3e-108 XK27_07525 3.6.1.55 F NUDIX domain
NMELFEPI_01047 2.4e-164 yxaM EGP Major facilitator Superfamily
NMELFEPI_01048 2.1e-88 S AAA domain
NMELFEPI_01049 8.4e-148 2.7.1.89 M Phosphotransferase enzyme family
NMELFEPI_01050 8.3e-84 3.6.1.55 F NUDIX domain
NMELFEPI_01051 3e-123 2.4.2.3 F Phosphorylase superfamily
NMELFEPI_01052 4.9e-81 6.3.3.2 S ASCH
NMELFEPI_01053 8.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NMELFEPI_01054 5.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NMELFEPI_01055 7.8e-147 rbsU U ribose uptake protein RbsU
NMELFEPI_01056 3.4e-157 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
NMELFEPI_01057 2.5e-204 G Transmembrane secretion effector
NMELFEPI_01058 2.1e-09 rnhA 3.1.26.4 L Caulimovirus viroplasmin
NMELFEPI_01059 2.1e-227 L COG3547 Transposase and inactivated derivatives
NMELFEPI_01061 3.2e-74 K Copper transport repressor CopY TcrY
NMELFEPI_01062 0.0 copB 3.6.3.4 P P-type ATPase
NMELFEPI_01065 5.5e-34
NMELFEPI_01066 1.4e-43 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NMELFEPI_01067 2e-08 S response to antibiotic
NMELFEPI_01068 5.2e-104 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
NMELFEPI_01069 3.1e-33 L PFAM Integrase catalytic region
NMELFEPI_01070 1.6e-104 L An automated process has identified a potential problem with this gene model
NMELFEPI_01071 7.9e-86 S CAAX protease self-immunity
NMELFEPI_01078 1.9e-161 mrr L restriction endonuclease
NMELFEPI_01079 6e-196 L COG2826 Transposase and inactivated derivatives, IS30 family
NMELFEPI_01080 8.9e-48 G Transmembrane secretion effector
NMELFEPI_01081 2.1e-09 rnhA 3.1.26.4 L Caulimovirus viroplasmin
NMELFEPI_01082 2.1e-227 L COG3547 Transposase and inactivated derivatives
NMELFEPI_01083 3.2e-281 V ABC-type multidrug transport system, ATPase and permease components
NMELFEPI_01084 3.1e-279 V ABC-type multidrug transport system, ATPase and permease components
NMELFEPI_01085 9.1e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NMELFEPI_01086 2.7e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NMELFEPI_01087 1.3e-176 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NMELFEPI_01088 2e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
NMELFEPI_01089 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NMELFEPI_01090 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NMELFEPI_01091 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NMELFEPI_01092 6.3e-90 ypmB S Protein conserved in bacteria
NMELFEPI_01093 6.4e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NMELFEPI_01094 5.3e-113 dnaD L DnaD domain protein
NMELFEPI_01095 5.5e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NMELFEPI_01096 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NMELFEPI_01097 6.6e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NMELFEPI_01098 2.2e-102 ypsA S Belongs to the UPF0398 family
NMELFEPI_01099 4.5e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NMELFEPI_01100 1.9e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NMELFEPI_01101 1.5e-241 cpdA S Calcineurin-like phosphoesterase
NMELFEPI_01102 3.2e-222 I transferase activity, transferring acyl groups other than amino-acyl groups
NMELFEPI_01103 1.7e-173 degV S DegV family
NMELFEPI_01104 7.8e-55
NMELFEPI_01105 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NMELFEPI_01106 2.9e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NMELFEPI_01107 1.2e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMELFEPI_01108 1.8e-195 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NMELFEPI_01109 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
NMELFEPI_01110 0.0 FbpA K Fibronectin-binding protein
NMELFEPI_01111 1.4e-63
NMELFEPI_01112 1e-162 degV S EDD domain protein, DegV family
NMELFEPI_01113 2.2e-151
NMELFEPI_01114 3.8e-146 K Transcriptional regulator
NMELFEPI_01115 9.2e-203 xerS L Belongs to the 'phage' integrase family
NMELFEPI_01116 8.8e-122 yoaK S Protein of unknown function (DUF1275)
NMELFEPI_01117 1.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMELFEPI_01118 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NMELFEPI_01119 1.1e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
NMELFEPI_01120 1.8e-178 K Transcriptional regulator
NMELFEPI_01121 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMELFEPI_01122 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMELFEPI_01123 2.4e-113 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NMELFEPI_01124 1.2e-106 lacA 2.3.1.79 S Transferase hexapeptide repeat
NMELFEPI_01125 1.8e-164 akr5f 1.1.1.346 S reductase
NMELFEPI_01126 3.6e-110 ybhL S Belongs to the BI1 family
NMELFEPI_01127 1.3e-32
NMELFEPI_01128 9.3e-172 4.1.1.45 S Amidohydrolase
NMELFEPI_01129 3.3e-236 yrvN L AAA C-terminal domain
NMELFEPI_01130 2e-18 K Transcriptional regulator
NMELFEPI_01131 6.8e-133 C Aldo keto reductase
NMELFEPI_01132 0.0 lmrA 3.6.3.44 V ABC transporter
NMELFEPI_01133 1.4e-72 K helix_turn_helix multiple antibiotic resistance protein
NMELFEPI_01134 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NMELFEPI_01135 1.9e-76 yphH S Cupin domain
NMELFEPI_01136 2.9e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NMELFEPI_01137 1.5e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NMELFEPI_01139 0.0 uvrA3 L excinuclease ABC, A subunit
NMELFEPI_01140 9.6e-139 S PFAM Archaeal ATPase
NMELFEPI_01141 6.3e-50 S PFAM Archaeal ATPase
NMELFEPI_01142 3.8e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NMELFEPI_01144 1.1e-138 H Nodulation protein S (NodS)
NMELFEPI_01145 2.5e-267 mntH P H( )-stimulated, divalent metal cation uptake system
NMELFEPI_01146 1.1e-53 yitW S Iron-sulfur cluster assembly protein
NMELFEPI_01147 1e-273 sufB O assembly protein SufB
NMELFEPI_01148 1.9e-80 nifU C SUF system FeS assembly protein, NifU family
NMELFEPI_01149 3.9e-229 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NMELFEPI_01150 2.1e-219 sufD O FeS assembly protein SufD
NMELFEPI_01151 3.2e-144 sufC O FeS assembly ATPase SufC
NMELFEPI_01153 5.9e-15 L Transposase
NMELFEPI_01154 2.1e-227 L COG3547 Transposase and inactivated derivatives
NMELFEPI_01155 2.7e-223 L Transposase
NMELFEPI_01156 1.3e-45 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMELFEPI_01157 1.1e-245 brnQ U Component of the transport system for branched-chain amino acids
NMELFEPI_01158 5.5e-61 S Putative adhesin
NMELFEPI_01159 3.1e-37 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NMELFEPI_01160 5.2e-11 S Peptidase propeptide and YPEB domain
NMELFEPI_01161 7.6e-60 S Peptidase propeptide and YPEB domain
NMELFEPI_01162 7.4e-36 T Transcriptional regulatory protein, C terminal
NMELFEPI_01163 5.9e-117 3.6.1.55 F NUDIX domain
NMELFEPI_01164 2.4e-107 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NMELFEPI_01166 1.9e-108 S Protein of unknown function (DUF1211)
NMELFEPI_01167 3.1e-133 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
NMELFEPI_01168 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NMELFEPI_01169 7.7e-82 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
NMELFEPI_01170 1.1e-275 lsa S ABC transporter
NMELFEPI_01171 2.9e-177 MA20_14895 S Conserved hypothetical protein 698
NMELFEPI_01172 7.6e-203 L Putative transposase DNA-binding domain
NMELFEPI_01173 9.5e-72
NMELFEPI_01175 1.2e-100 S LexA-binding, inner membrane-associated putative hydrolase
NMELFEPI_01176 1.4e-99 K LysR substrate binding domain
NMELFEPI_01177 6.5e-178 lacX 5.1.3.3 G Aldose 1-epimerase
NMELFEPI_01178 8.2e-252 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NMELFEPI_01179 1.3e-88 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NMELFEPI_01180 1.9e-172 xerC D Phage integrase, N-terminal SAM-like domain
NMELFEPI_01181 1.3e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NMELFEPI_01182 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMELFEPI_01183 7.3e-155 dprA LU DNA protecting protein DprA
NMELFEPI_01184 1.3e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMELFEPI_01185 4.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NMELFEPI_01186 5.7e-264 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NMELFEPI_01187 1.6e-35 yozE S Belongs to the UPF0346 family
NMELFEPI_01188 4.2e-150 DegV S Uncharacterised protein, DegV family COG1307
NMELFEPI_01189 5.8e-115 hlyIII S protein, hemolysin III
NMELFEPI_01190 2.3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NMELFEPI_01191 2.5e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMELFEPI_01192 9.3e-63 2.5.1.74 H UbiA prenyltransferase family
NMELFEPI_01193 0.0 L Helicase C-terminal domain protein
NMELFEPI_01194 3.7e-54 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
NMELFEPI_01195 1.4e-21
NMELFEPI_01196 1.9e-125 K SIR2-like domain
NMELFEPI_01197 1.4e-95 3.1.21.3 V Type I restriction modification DNA specificity domain
NMELFEPI_01198 4.1e-254 hsdM 2.1.1.72 V type I restriction-modification system
NMELFEPI_01200 1e-43 S RloB-like protein
NMELFEPI_01201 1.1e-138 S AAA domain, putative AbiEii toxin, Type IV TA system
NMELFEPI_01202 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
NMELFEPI_01203 1.8e-229 S Tetratricopeptide repeat protein
NMELFEPI_01204 6.7e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NMELFEPI_01205 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NMELFEPI_01206 6e-219 rpsA 1.17.7.4 J Ribosomal protein S1
NMELFEPI_01207 1.1e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NMELFEPI_01208 6.4e-97 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NMELFEPI_01209 3e-62 M Lysin motif
NMELFEPI_01210 5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NMELFEPI_01211 6.4e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NMELFEPI_01212 1.1e-133 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NMELFEPI_01213 7e-62 ribT K acetyltransferase
NMELFEPI_01214 1.7e-165 xerD D recombinase XerD
NMELFEPI_01215 1.2e-166 cvfB S S1 domain
NMELFEPI_01216 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NMELFEPI_01217 3e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NMELFEPI_01218 0.0 dnaE 2.7.7.7 L DNA polymerase
NMELFEPI_01219 2e-26 S Protein of unknown function (DUF2929)
NMELFEPI_01220 5.8e-307 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NMELFEPI_01221 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NMELFEPI_01222 3.4e-47 yrvD S Lipopolysaccharide assembly protein A domain
NMELFEPI_01223 3.6e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NMELFEPI_01224 3e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NMELFEPI_01225 0.0 oatA I Acyltransferase
NMELFEPI_01226 3.3e-239 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NMELFEPI_01227 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NMELFEPI_01228 8.6e-173 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
NMELFEPI_01229 2.1e-90 dedA 3.1.3.1 S SNARE associated Golgi protein
NMELFEPI_01230 3e-150 xerD L Phage integrase, N-terminal SAM-like domain
NMELFEPI_01231 1.8e-116 GM NmrA-like family
NMELFEPI_01232 7.2e-245 yagE E amino acid
NMELFEPI_01234 7.3e-94 S Rib/alpha-like repeat
NMELFEPI_01235 2.9e-66 S Domain of unknown function DUF1828
NMELFEPI_01236 7.2e-68
NMELFEPI_01237 7.1e-33
NMELFEPI_01238 9e-80 mutT 3.6.1.55 F NUDIX domain
NMELFEPI_01239 2.5e-62
NMELFEPI_01241 3.7e-160 htpX O Peptidase family M48
NMELFEPI_01242 2.2e-187 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NMELFEPI_01243 1.5e-131 L An automated process has identified a potential problem with this gene model
NMELFEPI_01244 1.9e-211 glf 5.4.99.9 M UDP-galactopyranose mutase
NMELFEPI_01245 1.6e-29 rfaJ 2.4.1.44, 2.4.1.58 GT8 M Glycosyl transferase family 8
NMELFEPI_01246 1.2e-34 M Glycosyltransferase like family 2
NMELFEPI_01247 2.3e-193 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
NMELFEPI_01248 9.3e-53
NMELFEPI_01251 1.5e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
NMELFEPI_01252 1.5e-89 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMELFEPI_01253 4.5e-62 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMELFEPI_01254 3.1e-224 L Transposase IS66 family
NMELFEPI_01255 1.2e-27 S Transposase C of IS166 homeodomain
NMELFEPI_01256 4.1e-59 L PFAM IS66 Orf2 family protein
NMELFEPI_01257 1e-89 wbbI M transferase activity, transferring glycosyl groups
NMELFEPI_01258 2.9e-49 M Glycosyltransferase like family 2
NMELFEPI_01259 3e-94 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
NMELFEPI_01260 2.4e-73 M Glycosyltransferase like family 2
NMELFEPI_01261 3.1e-49 GT4 M Glycosyl transferases group 1
NMELFEPI_01262 2e-32 pssE S Glycosyltransferase family 28 C-terminal domain
NMELFEPI_01263 5.4e-35 pssD M Oligosaccharide biosynthesis protein Alg14 like
NMELFEPI_01264 4.9e-114 M Glycosyltransferase
NMELFEPI_01265 4.2e-113 rfbP M Bacterial sugar transferase
NMELFEPI_01266 2.9e-142 ywqE 3.1.3.48 GM PHP domain protein
NMELFEPI_01267 9.3e-125 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NMELFEPI_01268 2.2e-146 epsB M biosynthesis protein
NMELFEPI_01269 2.4e-152 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NMELFEPI_01270 3.1e-81 K DNA-templated transcription, initiation
NMELFEPI_01271 3.7e-162
NMELFEPI_01272 2.5e-121 frnE Q DSBA-like thioredoxin domain
NMELFEPI_01273 3.3e-215
NMELFEPI_01274 2.3e-77 S Domain of unknown function (DUF4767)
NMELFEPI_01275 1e-116 frnE Q DSBA-like thioredoxin domain
NMELFEPI_01277 5.1e-82
NMELFEPI_01278 9.7e-88 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMELFEPI_01279 1.5e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
NMELFEPI_01280 1.3e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NMELFEPI_01281 9.5e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NMELFEPI_01282 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NMELFEPI_01283 4.2e-158
NMELFEPI_01284 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMELFEPI_01285 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NMELFEPI_01286 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
NMELFEPI_01287 1.2e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
NMELFEPI_01288 0.0 comEC S Competence protein ComEC
NMELFEPI_01289 6.3e-88 comEA L Competence protein ComEA
NMELFEPI_01290 1.4e-184 ylbL T Belongs to the peptidase S16 family
NMELFEPI_01291 9.6e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NMELFEPI_01292 1.2e-94 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NMELFEPI_01293 7.4e-50 ylbG S UPF0298 protein
NMELFEPI_01294 7.7e-211 ftsW D Belongs to the SEDS family
NMELFEPI_01295 0.0 typA T GTP-binding protein TypA
NMELFEPI_01296 5.2e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NMELFEPI_01297 2.3e-34 ykzG S Belongs to the UPF0356 family
NMELFEPI_01298 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMELFEPI_01299 1.7e-168 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NMELFEPI_01300 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NMELFEPI_01301 1.3e-114 S Repeat protein
NMELFEPI_01302 3.1e-124 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NMELFEPI_01303 1.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NMELFEPI_01304 9.6e-58 XK27_04120 S Putative amino acid metabolism
NMELFEPI_01305 2.8e-213 iscS 2.8.1.7 E Aminotransferase class V
NMELFEPI_01306 4.5e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NMELFEPI_01308 1.7e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NMELFEPI_01309 2.3e-33 cspA K 'Cold-shock' DNA-binding domain
NMELFEPI_01310 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NMELFEPI_01311 3.4e-114 gpsB D DivIVA domain protein
NMELFEPI_01312 8.5e-145 ylmH S S4 domain protein
NMELFEPI_01313 1.2e-27 yggT S YGGT family
NMELFEPI_01314 1.3e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NMELFEPI_01315 1.5e-245 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NMELFEPI_01316 6e-239 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NMELFEPI_01317 1.4e-150 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NMELFEPI_01318 3.4e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NMELFEPI_01319 3.4e-258 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NMELFEPI_01320 7e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NMELFEPI_01321 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NMELFEPI_01322 4.8e-55 ftsL D Cell division protein FtsL
NMELFEPI_01323 3.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NMELFEPI_01324 4.1e-77 mraZ K Belongs to the MraZ family
NMELFEPI_01325 2.7e-52 S Protein of unknown function (DUF3397)
NMELFEPI_01326 3.6e-13 S Protein of unknown function (DUF4044)
NMELFEPI_01327 1.6e-94 mreD
NMELFEPI_01328 6.1e-141 mreC M Involved in formation and maintenance of cell shape
NMELFEPI_01329 2.7e-164 mreB D cell shape determining protein MreB
NMELFEPI_01330 2.1e-111 radC L DNA repair protein
NMELFEPI_01331 2e-123 S Haloacid dehalogenase-like hydrolase
NMELFEPI_01332 2e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NMELFEPI_01333 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NMELFEPI_01334 0.0 3.6.3.8 P P-type ATPase
NMELFEPI_01335 4.6e-118 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NMELFEPI_01336 2.1e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMELFEPI_01337 4.6e-216 iscS2 2.8.1.7 E Aminotransferase class V
NMELFEPI_01338 5.5e-290 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NMELFEPI_01340 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NMELFEPI_01341 5e-81 yueI S Protein of unknown function (DUF1694)
NMELFEPI_01342 1.4e-237 rarA L recombination factor protein RarA
NMELFEPI_01344 5.2e-81 usp6 T universal stress protein
NMELFEPI_01345 2e-222 rodA D Belongs to the SEDS family
NMELFEPI_01346 6.6e-34 S Protein of unknown function (DUF2969)
NMELFEPI_01347 2.6e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NMELFEPI_01348 6.8e-13 S DNA-directed RNA polymerase subunit beta
NMELFEPI_01349 1.7e-179 mbl D Cell shape determining protein MreB Mrl
NMELFEPI_01350 2.4e-31 ywzB S Protein of unknown function (DUF1146)
NMELFEPI_01351 1.4e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NMELFEPI_01352 9.6e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NMELFEPI_01353 1.7e-168 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NMELFEPI_01354 6.7e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NMELFEPI_01355 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMELFEPI_01356 3.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NMELFEPI_01357 4.7e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMELFEPI_01358 1.1e-127 atpB C it plays a direct role in the translocation of protons across the membrane
NMELFEPI_01359 1.5e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NMELFEPI_01360 5.9e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NMELFEPI_01361 7.1e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NMELFEPI_01362 3.8e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NMELFEPI_01363 5.5e-112 tdk 2.7.1.21 F thymidine kinase
NMELFEPI_01364 4.9e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
NMELFEPI_01365 2.3e-195 ampC V Beta-lactamase
NMELFEPI_01368 3.2e-69
NMELFEPI_01369 8.9e-238 EGP Major facilitator Superfamily
NMELFEPI_01370 1.9e-261 pgi 5.3.1.9 G Belongs to the GPI family
NMELFEPI_01371 1e-105 vanZ V VanZ like family
NMELFEPI_01372 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NMELFEPI_01373 1.7e-174 L Psort location Cytoplasmic, score
NMELFEPI_01374 1.4e-267 T PhoQ Sensor
NMELFEPI_01375 6.4e-128 K Transcriptional regulatory protein, C terminal
NMELFEPI_01376 6e-67 S SdpI/YhfL protein family
NMELFEPI_01377 1.9e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
NMELFEPI_01378 2.2e-181 patB 4.4.1.8 E Aminotransferase, class I
NMELFEPI_01379 1.2e-18 M Protein of unknown function (DUF3737)
NMELFEPI_01380 5.5e-55 M Protein of unknown function (DUF3737)
NMELFEPI_01381 2e-199 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NMELFEPI_01383 1e-226 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NMELFEPI_01384 4.7e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
NMELFEPI_01385 8.8e-81 comGF U Putative Competence protein ComGF
NMELFEPI_01386 1.7e-10
NMELFEPI_01387 1.7e-56
NMELFEPI_01388 1.5e-38 comGC U Required for transformation and DNA binding
NMELFEPI_01389 1e-171 comGB NU type II secretion system
NMELFEPI_01390 7.9e-177 comGA NU Type II IV secretion system protein
NMELFEPI_01391 1.5e-132 yebC K Transcriptional regulatory protein
NMELFEPI_01392 1.4e-95 S VanZ like family
NMELFEPI_01393 4.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NMELFEPI_01394 1.8e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
NMELFEPI_01395 4e-147 yisY 1.11.1.10 S Alpha/beta hydrolase family
NMELFEPI_01396 5.1e-109
NMELFEPI_01397 2.7e-198 S Putative adhesin
NMELFEPI_01398 3.4e-61 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMELFEPI_01399 7.7e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMELFEPI_01400 2.9e-148 S Sucrose-6F-phosphate phosphohydrolase
NMELFEPI_01401 1.7e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NMELFEPI_01402 7.6e-172 ybbR S YbbR-like protein
NMELFEPI_01403 2.9e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMELFEPI_01404 5.9e-210 potD P ABC transporter
NMELFEPI_01405 2.9e-137 potC P ABC transporter permease
NMELFEPI_01406 1.2e-130 potB P ABC transporter permease
NMELFEPI_01407 6e-202 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NMELFEPI_01408 2e-166 murB 1.3.1.98 M Cell wall formation
NMELFEPI_01409 1.2e-99 dnaQ 2.7.7.7 L DNA polymerase III
NMELFEPI_01410 2.2e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NMELFEPI_01411 2.9e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NMELFEPI_01412 2.8e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NMELFEPI_01413 1.2e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
NMELFEPI_01414 2.9e-93
NMELFEPI_01415 1.2e-76
NMELFEPI_01416 4.2e-106 3.2.2.20 K acetyltransferase
NMELFEPI_01417 8.7e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NMELFEPI_01418 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NMELFEPI_01419 1.9e-28 secG U Preprotein translocase
NMELFEPI_01420 3.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NMELFEPI_01421 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NMELFEPI_01422 4.6e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NMELFEPI_01423 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NMELFEPI_01424 1.4e-187 cggR K Putative sugar-binding domain
NMELFEPI_01426 2.6e-277 ycaM E amino acid
NMELFEPI_01427 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NMELFEPI_01428 6.2e-171 whiA K May be required for sporulation
NMELFEPI_01429 5.8e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NMELFEPI_01430 6e-160 rapZ S Displays ATPase and GTPase activities
NMELFEPI_01431 8.1e-91 S Short repeat of unknown function (DUF308)
NMELFEPI_01432 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NMELFEPI_01433 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NMELFEPI_01434 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NMELFEPI_01435 4.1e-149 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NMELFEPI_01436 6.8e-257 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NMELFEPI_01437 2.4e-204 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NMELFEPI_01438 7.8e-156 lacR K Transcriptional regulator
NMELFEPI_01439 4.6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NMELFEPI_01440 1.3e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NMELFEPI_01441 4.5e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NMELFEPI_01442 5.2e-173 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NMELFEPI_01443 7.6e-24
NMELFEPI_01444 3.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NMELFEPI_01445 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NMELFEPI_01446 1.3e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NMELFEPI_01447 4.1e-124 comFC S Competence protein
NMELFEPI_01448 4.5e-219 comFA L Helicase C-terminal domain protein
NMELFEPI_01449 5.3e-116 yvyE 3.4.13.9 S YigZ family
NMELFEPI_01450 1.6e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
NMELFEPI_01451 6.9e-194 rny S Endoribonuclease that initiates mRNA decay
NMELFEPI_01452 6e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NMELFEPI_01453 3e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMELFEPI_01454 7.5e-125 ymfM S Helix-turn-helix domain
NMELFEPI_01455 2.3e-128 IQ Enoyl-(Acyl carrier protein) reductase
NMELFEPI_01456 9.2e-231 S Peptidase M16
NMELFEPI_01457 1.1e-228 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
NMELFEPI_01458 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NMELFEPI_01459 1.9e-74 WQ51_03320 S Protein of unknown function (DUF1149)
NMELFEPI_01460 5.1e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NMELFEPI_01461 3e-207 yubA S AI-2E family transporter
NMELFEPI_01462 7.1e-65 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NMELFEPI_01463 4.5e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NMELFEPI_01464 1.1e-231 N Uncharacterized conserved protein (DUF2075)
NMELFEPI_01465 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NMELFEPI_01466 1.1e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMELFEPI_01467 7.3e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMELFEPI_01468 5.2e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
NMELFEPI_01469 6.9e-110 yjbK S CYTH
NMELFEPI_01470 5.9e-106 yjbH Q Thioredoxin
NMELFEPI_01471 7.7e-147 coiA 3.6.4.12 S Competence protein
NMELFEPI_01472 4.7e-117 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NMELFEPI_01473 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NMELFEPI_01474 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NMELFEPI_01475 4.2e-40 ptsH G phosphocarrier protein HPR
NMELFEPI_01476 5.9e-25
NMELFEPI_01477 0.0 clpE O Belongs to the ClpA ClpB family
NMELFEPI_01478 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
NMELFEPI_01479 4.3e-302 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NMELFEPI_01480 3.6e-157 hlyX S Transporter associated domain
NMELFEPI_01481 5.4e-75
NMELFEPI_01482 7e-89
NMELFEPI_01483 2.4e-112 ygaC J Belongs to the UPF0374 family
NMELFEPI_01484 7.8e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
NMELFEPI_01485 3.9e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMELFEPI_01486 2.7e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NMELFEPI_01487 1.1e-218 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NMELFEPI_01488 1.4e-217 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
NMELFEPI_01489 1.9e-180 D Alpha beta
NMELFEPI_01491 1.9e-147 S haloacid dehalogenase-like hydrolase
NMELFEPI_01492 2.4e-204 EGP Major facilitator Superfamily
NMELFEPI_01493 9.2e-261 glnA 6.3.1.2 E glutamine synthetase
NMELFEPI_01494 1.7e-165 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NMELFEPI_01495 8.1e-19 S Protein of unknown function (DUF3042)
NMELFEPI_01496 5.1e-58 yqhL P Rhodanese-like protein
NMELFEPI_01497 7.9e-35 yqgQ S Bacterial protein of unknown function (DUF910)
NMELFEPI_01498 4e-119 gluP 3.4.21.105 S Rhomboid family
NMELFEPI_01499 1.4e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NMELFEPI_01500 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NMELFEPI_01501 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NMELFEPI_01502 0.0 S membrane
NMELFEPI_01503 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NMELFEPI_01504 3.2e-203 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NMELFEPI_01505 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMELFEPI_01506 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NMELFEPI_01507 6.2e-63 yodB K Transcriptional regulator, HxlR family
NMELFEPI_01508 2.8e-137 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMELFEPI_01509 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NMELFEPI_01510 3.2e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMELFEPI_01511 1e-279 arlS 2.7.13.3 T Histidine kinase
NMELFEPI_01512 1.1e-130 K response regulator
NMELFEPI_01513 1.8e-93 yceD S Uncharacterized ACR, COG1399
NMELFEPI_01514 1.6e-216 ylbM S Belongs to the UPF0348 family
NMELFEPI_01515 3.7e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NMELFEPI_01516 1.7e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NMELFEPI_01517 5.3e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NMELFEPI_01518 2.3e-209 yqeH S Ribosome biogenesis GTPase YqeH
NMELFEPI_01519 7.3e-89 yqeG S HAD phosphatase, family IIIA
NMELFEPI_01520 2.6e-167 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NMELFEPI_01521 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NMELFEPI_01522 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NMELFEPI_01523 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NMELFEPI_01524 8.1e-235 S CAAX protease self-immunity
NMELFEPI_01525 1.6e-73 S Protein of unknown function (DUF3021)
NMELFEPI_01526 1.1e-74 K LytTr DNA-binding domain
NMELFEPI_01527 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMELFEPI_01528 2e-150 dnaI L Primosomal protein DnaI
NMELFEPI_01529 5.3e-240 dnaB L Replication initiation and membrane attachment
NMELFEPI_01530 7.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NMELFEPI_01531 6e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NMELFEPI_01532 5.7e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NMELFEPI_01533 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMELFEPI_01534 6.3e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NMELFEPI_01535 4.1e-121 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMELFEPI_01536 4.7e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NMELFEPI_01537 1.1e-62
NMELFEPI_01538 2.3e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NMELFEPI_01539 1.6e-224 ecsB U ABC transporter
NMELFEPI_01540 9.7e-135 ecsA V ABC transporter, ATP-binding protein
NMELFEPI_01541 9.2e-77 hit FG Scavenger mRNA decapping enzyme C-term binding
NMELFEPI_01542 5.2e-52
NMELFEPI_01543 9.5e-24 S YtxH-like protein
NMELFEPI_01544 2.1e-147 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NMELFEPI_01545 3e-184 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
NMELFEPI_01546 0.0 L AAA domain
NMELFEPI_01547 4e-218 yhaO L Ser Thr phosphatase family protein
NMELFEPI_01548 3.6e-55 yheA S Belongs to the UPF0342 family
NMELFEPI_01549 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NMELFEPI_01550 7.1e-158 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMELFEPI_01552 0.0 GH23 S M26 IgA1-specific Metallo-endopeptidase C-terminal region
NMELFEPI_01553 2.9e-77 3.6.1.55 L NUDIX domain
NMELFEPI_01554 1.9e-112 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
NMELFEPI_01555 6.8e-195 V Beta-lactamase
NMELFEPI_01556 1.5e-64 ung2 3.2.2.27 L Uracil-DNA glycosylase
NMELFEPI_01557 2.2e-111 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NMELFEPI_01558 2.2e-91 dps P Belongs to the Dps family
NMELFEPI_01559 7.9e-35 copZ C Heavy-metal-associated domain
NMELFEPI_01560 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NMELFEPI_01561 1.1e-48 XK27_01125 L PFAM IS66 Orf2 family protein
NMELFEPI_01562 2.8e-25
NMELFEPI_01563 1.1e-191 L COG3547 Transposase and inactivated derivatives
NMELFEPI_01564 1.5e-244 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMELFEPI_01565 7.6e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMELFEPI_01566 4.7e-120 spaE S ABC-2 family transporter protein
NMELFEPI_01567 1.2e-126 mutF V ABC transporter, ATP-binding protein
NMELFEPI_01568 9.9e-242 nhaC C Na H antiporter NhaC
NMELFEPI_01569 1.6e-205 L Putative transposase DNA-binding domain
NMELFEPI_01570 6.7e-57 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
NMELFEPI_01571 1.9e-95 S UPF0397 protein
NMELFEPI_01572 0.0 ykoD P ABC transporter, ATP-binding protein
NMELFEPI_01573 6.3e-143 cbiQ P cobalt transport
NMELFEPI_01574 2.1e-118 ybhL S Belongs to the BI1 family
NMELFEPI_01575 0.0 GT2,GT4 M family 8
NMELFEPI_01576 0.0 GT2,GT4 M family 8
NMELFEPI_01577 6.3e-27 UW Tetratricopeptide repeat
NMELFEPI_01578 7.6e-45 UW Tetratricopeptide repeat
NMELFEPI_01579 4.4e-94 UW Tetratricopeptide repeat
NMELFEPI_01580 1.3e-67 UW Tetratricopeptide repeat
NMELFEPI_01582 2.9e-148 S hydrolase
NMELFEPI_01584 9e-167 yegS 2.7.1.107 G Lipid kinase
NMELFEPI_01585 6e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMELFEPI_01586 5.2e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NMELFEPI_01587 3.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMELFEPI_01588 1.9e-206 camS S sex pheromone
NMELFEPI_01589 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NMELFEPI_01590 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NMELFEPI_01591 2.2e-111 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
NMELFEPI_01592 5.3e-102 S ECF transporter, substrate-specific component
NMELFEPI_01594 1.1e-83 ydcK S Belongs to the SprT family
NMELFEPI_01595 1.2e-131 M Glycosyltransferase sugar-binding region containing DXD motif
NMELFEPI_01596 6.2e-255 epsU S Polysaccharide biosynthesis protein
NMELFEPI_01597 3.7e-226 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NMELFEPI_01598 0.0 pacL 3.6.3.8 P P-type ATPase
NMELFEPI_01599 1.2e-294 spoVK O ATPase family associated with various cellular activities (AAA)
NMELFEPI_01600 1.3e-22 spoVK O ATPase family associated with various cellular activities (AAA)
NMELFEPI_01601 6.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NMELFEPI_01602 2.7e-282 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NMELFEPI_01603 0.0 S Glycosyltransferase like family 2
NMELFEPI_01604 2.7e-205 csaB M Glycosyl transferases group 1
NMELFEPI_01605 1.6e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NMELFEPI_01606 7.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
NMELFEPI_01607 1.6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
NMELFEPI_01608 3.6e-123 gntR1 K UTRA
NMELFEPI_01609 6.7e-188
NMELFEPI_01610 1.9e-52 P Rhodanese Homology Domain
NMELFEPI_01613 9.9e-166 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
NMELFEPI_01614 1.9e-36 K SIS domain
NMELFEPI_01615 1.5e-35 yjgN S Bacterial protein of unknown function (DUF898)
NMELFEPI_01617 2.6e-84 M LysM domain protein
NMELFEPI_01618 7.8e-114 M LysM domain protein
NMELFEPI_01619 5.4e-127 S Putative ABC-transporter type IV
NMELFEPI_01620 6.2e-59 psiE S Phosphate-starvation-inducible E
NMELFEPI_01621 9.3e-92 K acetyltransferase
NMELFEPI_01623 1.4e-141 yvgN C Aldo keto reductase
NMELFEPI_01624 7.5e-247 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NMELFEPI_01625 6e-85 S Uncharacterized protein conserved in bacteria (DUF2263)
NMELFEPI_01626 4.6e-38 S Uncharacterized protein conserved in bacteria (DUF2263)
NMELFEPI_01627 1.7e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NMELFEPI_01628 0.0 lhr L DEAD DEAH box helicase
NMELFEPI_01629 3.2e-253 P P-loop Domain of unknown function (DUF2791)
NMELFEPI_01630 0.0 S TerB-C domain
NMELFEPI_01631 4.1e-37 4.1.1.44 S decarboxylase
NMELFEPI_01632 1.1e-53 4.1.1.44 S decarboxylase
NMELFEPI_01633 1.5e-71
NMELFEPI_01634 1.7e-174 L Psort location Cytoplasmic, score
NMELFEPI_01635 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NMELFEPI_01636 1.2e-244 cycA E Amino acid permease
NMELFEPI_01638 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
NMELFEPI_01655 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
NMELFEPI_01656 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NMELFEPI_01657 7.9e-180 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NMELFEPI_01658 1.3e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
NMELFEPI_01659 1.3e-218 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
NMELFEPI_01671 1.9e-59
NMELFEPI_01672 8.5e-248 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMELFEPI_01689 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
NMELFEPI_01690 9.5e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NMELFEPI_01691 4.1e-98 J Acetyltransferase (GNAT) domain
NMELFEPI_01692 5.3e-107 yjbF S SNARE associated Golgi protein
NMELFEPI_01693 5e-153 I alpha/beta hydrolase fold
NMELFEPI_01694 2.3e-119 hipB K Helix-turn-helix
NMELFEPI_01695 1.5e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
NMELFEPI_01696 1.8e-24 hipB K Helix-turn-helix
NMELFEPI_01697 7.8e-255 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NMELFEPI_01698 1.6e-177
NMELFEPI_01699 2.9e-125 S SNARE associated Golgi protein
NMELFEPI_01700 2e-141 cof S haloacid dehalogenase-like hydrolase
NMELFEPI_01701 0.0 ydgH S MMPL family
NMELFEPI_01702 8.8e-96 yobS K Bacterial regulatory proteins, tetR family
NMELFEPI_01703 6.5e-160 3.5.2.6 V Beta-lactamase enzyme family
NMELFEPI_01704 2e-166 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
NMELFEPI_01705 2.6e-79 yjcF S Acetyltransferase (GNAT) domain
NMELFEPI_01706 2.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NMELFEPI_01707 2.4e-75 yybA 2.3.1.57 K Transcriptional regulator
NMELFEPI_01708 2.9e-39 ypaA S Protein of unknown function (DUF1304)
NMELFEPI_01709 5.7e-239 G Bacterial extracellular solute-binding protein
NMELFEPI_01710 3.3e-247 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
NMELFEPI_01711 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
NMELFEPI_01712 2.1e-157 gtsB P ABC-type sugar transport systems, permease components
NMELFEPI_01713 1.6e-202 malK P ATPases associated with a variety of cellular activities
NMELFEPI_01714 1.9e-222 pipD E Dipeptidase
NMELFEPI_01715 1.7e-34 pipD E Dipeptidase
NMELFEPI_01716 4.2e-201 L Putative transposase DNA-binding domain
NMELFEPI_01717 1.1e-153 endA F DNA RNA non-specific endonuclease
NMELFEPI_01718 1e-156 dkg S reductase
NMELFEPI_01719 4.2e-198 ltrA S Bacterial low temperature requirement A protein (LtrA)
NMELFEPI_01720 9.5e-183 dnaQ 2.7.7.7 L EXOIII
NMELFEPI_01721 1.1e-149 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NMELFEPI_01722 2e-112 yviA S Protein of unknown function (DUF421)
NMELFEPI_01723 7.8e-71 S Protein of unknown function (DUF3290)
NMELFEPI_01724 3.2e-239 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NMELFEPI_01725 6.2e-91 S PAS domain
NMELFEPI_01726 5.9e-143 pnuC H nicotinamide mononucleotide transporter
NMELFEPI_01727 8.3e-42 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NMELFEPI_01728 9e-133 S PAS domain
NMELFEPI_01729 1.5e-237 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMELFEPI_01730 8.8e-136 L transposase, IS605 OrfB family
NMELFEPI_01731 1.1e-64 tlpA2 L Transposase IS200 like
NMELFEPI_01732 3.2e-206 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
NMELFEPI_01733 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NMELFEPI_01734 3.6e-16
NMELFEPI_01735 2.1e-134 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylase
NMELFEPI_01736 1.6e-26 S Omega Transcriptional Repressor
NMELFEPI_01737 5e-145 G PTS system mannose/fructose/sorbose family IID component
NMELFEPI_01738 2.2e-140 G PTS system sorbose-specific iic component
NMELFEPI_01739 1.4e-162 2.7.1.191 G PTS system sorbose subfamily IIB component
NMELFEPI_01740 1.1e-59 V Type II restriction enzyme, methylase subunits
NMELFEPI_01741 7.3e-156 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NMELFEPI_01742 7.5e-127 S ABC-2 family transporter protein
NMELFEPI_01743 6.7e-170 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
NMELFEPI_01744 1.9e-107 K Cro/C1-type HTH DNA-binding domain
NMELFEPI_01745 1.2e-87 L Integrase
NMELFEPI_01747 1.7e-41 L Transposase
NMELFEPI_01748 3.1e-87 D AAA domain
NMELFEPI_01749 1.4e-38
NMELFEPI_01752 1.3e-236 EGP Major facilitator Superfamily
NMELFEPI_01753 1.1e-19 yrkL S Flavodoxin-like fold
NMELFEPI_01754 3.3e-156 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NMELFEPI_01755 1.2e-24 yrkL S Flavodoxin-like fold
NMELFEPI_01757 2.5e-133 L InterPro IPR002560 Transposase, IS204 IS1001 IS1096 IS1165
NMELFEPI_01758 9.9e-38 D Relaxase/Mobilisation nuclease domain
NMELFEPI_01759 4.7e-12 S Bacterial mobilisation protein (MobC)
NMELFEPI_01760 2.2e-87 S Phage plasmid primase, P4
NMELFEPI_01761 8.3e-40 L Belongs to the 'phage' integrase family
NMELFEPI_01762 0.0 oppA E ABC transporter substrate-binding protein
NMELFEPI_01763 2.2e-152 EG EamA-like transporter family
NMELFEPI_01764 6.3e-271 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMELFEPI_01765 4.1e-183 bglP 2.7.1.211 G phosphotransferase system
NMELFEPI_01766 2.4e-122 bglP 2.7.1.211 G phosphotransferase system
NMELFEPI_01767 1.7e-135 licT K CAT RNA binding domain
NMELFEPI_01768 7.5e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NMELFEPI_01769 1.9e-163 coaA 2.7.1.33 F Pantothenic acid kinase
NMELFEPI_01770 3.4e-103 E GDSL-like Lipase/Acylhydrolase
NMELFEPI_01771 4.1e-122 yvpB S Peptidase_C39 like family
NMELFEPI_01772 0.0 helD 3.6.4.12 L DNA helicase
NMELFEPI_01773 1.1e-115 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NMELFEPI_01775 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
NMELFEPI_01776 7e-27 rpiR1 K Helix-turn-helix domain, rpiR family
NMELFEPI_01777 5.4e-149 xth 3.1.11.2 L exodeoxyribonuclease III
NMELFEPI_01778 1.3e-52
NMELFEPI_01779 1.6e-26
NMELFEPI_01780 4.7e-125 pgm3 G Phosphoglycerate mutase family
NMELFEPI_01781 0.0 V FtsX-like permease family
NMELFEPI_01782 1.3e-131 cysA V ABC transporter, ATP-binding protein
NMELFEPI_01783 4.9e-276 E amino acid
NMELFEPI_01784 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NMELFEPI_01785 6.9e-231 S Putative peptidoglycan binding domain
NMELFEPI_01786 1.1e-114 M NlpC P60 family protein
NMELFEPI_01787 6e-97 gmk2 2.7.4.8 F Guanylate kinase
NMELFEPI_01788 1.5e-43
NMELFEPI_01789 6.8e-268 S O-antigen ligase like membrane protein
NMELFEPI_01790 9.1e-110
NMELFEPI_01791 9e-203 L COG2826 Transposase and inactivated derivatives, IS30 family
NMELFEPI_01792 2.9e-81 nrdI F Belongs to the NrdI family
NMELFEPI_01793 1.6e-67 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMELFEPI_01794 4.9e-96 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMELFEPI_01795 3.8e-79
NMELFEPI_01796 4.7e-60 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NMELFEPI_01797 4e-40
NMELFEPI_01798 5.9e-69 S Threonine/Serine exporter, ThrE
NMELFEPI_01799 2.3e-118 thrE S Putative threonine/serine exporter
NMELFEPI_01800 3.8e-282 S ABC transporter
NMELFEPI_01801 9e-60
NMELFEPI_01802 3.8e-36
NMELFEPI_01803 3.1e-209 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NMELFEPI_01804 0.0 pepF E oligoendopeptidase F
NMELFEPI_01805 2.7e-253 lctP C L-lactate permease
NMELFEPI_01806 2.5e-133 znuB U ABC 3 transport family
NMELFEPI_01807 7.3e-118 fhuC P ABC transporter
NMELFEPI_01808 3.3e-153 psaA P Belongs to the bacterial solute-binding protein 9 family
NMELFEPI_01809 4.1e-23 K helix_turn_helix, Arsenical Resistance Operon Repressor
NMELFEPI_01810 2.1e-227 L COG3547 Transposase and inactivated derivatives
NMELFEPI_01811 5.8e-138 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
NMELFEPI_01812 0.0 2.7.7.7 M domain protein
NMELFEPI_01813 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
NMELFEPI_01814 7.7e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NMELFEPI_01815 2e-135 fruR K DeoR C terminal sensor domain
NMELFEPI_01816 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NMELFEPI_01817 9.5e-220 natB CP ABC-2 family transporter protein
NMELFEPI_01818 1.7e-165 natA S ABC transporter, ATP-binding protein
NMELFEPI_01819 4.8e-142 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NMELFEPI_01820 7.7e-307 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NMELFEPI_01821 7.6e-203 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
NMELFEPI_01822 7.4e-121 K response regulator
NMELFEPI_01823 0.0 V ABC transporter
NMELFEPI_01824 2.7e-297 V ABC transporter, ATP-binding protein
NMELFEPI_01825 2e-133 XK27_01040 S Protein of unknown function (DUF1129)
NMELFEPI_01826 3.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NMELFEPI_01827 1.1e-42 yyzM S Bacterial protein of unknown function (DUF951)
NMELFEPI_01828 2.2e-154 spo0J K Belongs to the ParB family
NMELFEPI_01829 3.3e-138 soj D Sporulation initiation inhibitor
NMELFEPI_01830 3.8e-154 noc K Belongs to the ParB family
NMELFEPI_01831 6.3e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NMELFEPI_01832 6.4e-96 cvpA S Colicin V production protein
NMELFEPI_01833 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NMELFEPI_01834 1.4e-147 3.1.3.48 T Tyrosine phosphatase family
NMELFEPI_01835 1e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
NMELFEPI_01836 3.7e-99 azr 1.5.1.36 S NADPH-dependent FMN reductase
NMELFEPI_01837 6.4e-96 nqr 1.5.1.36 S reductase
NMELFEPI_01838 1.4e-107 K WHG domain
NMELFEPI_01839 3e-37
NMELFEPI_01840 7.7e-266 pipD E Dipeptidase
NMELFEPI_01841 2e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NMELFEPI_01842 7.9e-183 hrtB V ABC transporter permease
NMELFEPI_01843 7.1e-92 ygfC K Bacterial regulatory proteins, tetR family
NMELFEPI_01844 4.6e-111 G phosphoglycerate mutase
NMELFEPI_01845 3.6e-114 G Phosphoglycerate mutase family
NMELFEPI_01846 7e-141 aroD S Alpha/beta hydrolase family
NMELFEPI_01847 6e-140 S Belongs to the UPF0246 family
NMELFEPI_01848 8.5e-52
NMELFEPI_01849 1.3e-128
NMELFEPI_01850 3.9e-162 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NMELFEPI_01851 1e-201 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMELFEPI_01852 1.4e-37 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMELFEPI_01853 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NMELFEPI_01854 4.9e-60 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
NMELFEPI_01855 1.1e-43 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
NMELFEPI_01856 1.7e-151 ybbH_2 K Helix-turn-helix domain, rpiR family
NMELFEPI_01857 5.2e-155 2.7.7.12 C Domain of unknown function (DUF4931)
NMELFEPI_01858 5.6e-71 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
NMELFEPI_01859 1.1e-153
NMELFEPI_01860 2.5e-217 mdtG EGP Major facilitator Superfamily
NMELFEPI_01861 3.2e-124 puuD S peptidase C26
NMELFEPI_01862 5.3e-295 V ABC transporter transmembrane region
NMELFEPI_01863 2.9e-90 ymdB S Macro domain protein
NMELFEPI_01864 1.8e-183 V ABC-type multidrug transport system, ATPase and permease components
NMELFEPI_01865 1.1e-196 V ABC-type multidrug transport system, ATPase and permease components
NMELFEPI_01867 1.3e-36
NMELFEPI_01868 0.0 scrA 2.7.1.199, 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
NMELFEPI_01869 7.9e-298 scrB 3.2.1.26 GH32 G invertase
NMELFEPI_01870 1e-184 scrR K Transcriptional regulator, LacI family
NMELFEPI_01871 2.9e-142 ptp2 3.1.3.48 T Tyrosine phosphatase family
NMELFEPI_01872 3.2e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NMELFEPI_01873 2.1e-131 cobQ S glutamine amidotransferase
NMELFEPI_01874 4.6e-255 yfnA E Amino Acid
NMELFEPI_01875 3.9e-162 EG EamA-like transporter family
NMELFEPI_01876 4e-192 asnA 6.3.1.1 F aspartate--ammonia ligase
NMELFEPI_01877 1.6e-234 steT_1 E amino acid
NMELFEPI_01878 1e-136 puuD S peptidase C26
NMELFEPI_01879 7.9e-231 yifK E Amino acid permease
NMELFEPI_01880 2.5e-253 yifK E Amino acid permease
NMELFEPI_01881 1.8e-65 manO S Domain of unknown function (DUF956)
NMELFEPI_01882 1.1e-172 manN G system, mannose fructose sorbose family IID component
NMELFEPI_01883 1.3e-124 manY G PTS system
NMELFEPI_01884 4e-184 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NMELFEPI_01885 1.5e-247 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NMELFEPI_01887 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
NMELFEPI_01891 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
NMELFEPI_01895 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
NMELFEPI_01899 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
NMELFEPI_01902 2.4e-251 yfnA E Amino Acid
NMELFEPI_01903 0.0 clpE2 O AAA domain (Cdc48 subfamily)
NMELFEPI_01904 6.6e-162 S Alpha/beta hydrolase of unknown function (DUF915)
NMELFEPI_01905 2.7e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMELFEPI_01906 5.4e-39
NMELFEPI_01907 3.6e-216 lmrP E Major Facilitator Superfamily
NMELFEPI_01908 2.7e-143 pbpX2 V Beta-lactamase
NMELFEPI_01909 1.3e-251 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NMELFEPI_01910 6.7e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMELFEPI_01911 7.4e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
NMELFEPI_01912 4.8e-290 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMELFEPI_01914 3.9e-39
NMELFEPI_01915 7.5e-203 ywhK S Membrane
NMELFEPI_01916 8.8e-84 ykuL S (CBS) domain
NMELFEPI_01917 0.0 cadA P P-type ATPase
NMELFEPI_01918 1.9e-201 napA P Sodium/hydrogen exchanger family
NMELFEPI_01919 6.1e-38 S Putative adhesin
NMELFEPI_01920 2e-47 S Putative adhesin
NMELFEPI_01921 1.1e-281 V ABC transporter transmembrane region
NMELFEPI_01922 1.6e-160 mutR K Helix-turn-helix XRE-family like proteins
NMELFEPI_01923 3e-34
NMELFEPI_01924 7.9e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NMELFEPI_01925 2.8e-155 S Protein of unknown function (DUF979)
NMELFEPI_01926 2.8e-112 S Protein of unknown function (DUF969)
NMELFEPI_01927 1.1e-75 S Protein of unknown function (DUF805)
NMELFEPI_01928 3.4e-07
NMELFEPI_01929 4.2e-15
NMELFEPI_01930 8.8e-265 G PTS system Galactitol-specific IIC component
NMELFEPI_01931 2.6e-94 S Protein of unknown function (DUF1440)
NMELFEPI_01932 1.2e-101 S CAAX protease self-immunity
NMELFEPI_01933 3.8e-199 S DUF218 domain
NMELFEPI_01934 0.0 macB_3 V ABC transporter, ATP-binding protein
NMELFEPI_01935 1.2e-266 cydA 1.10.3.14 C ubiquinol oxidase
NMELFEPI_01936 5.3e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NMELFEPI_01937 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NMELFEPI_01938 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NMELFEPI_01939 2.4e-175 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NMELFEPI_01940 3.7e-168 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
NMELFEPI_01941 1.7e-180 tcsA S ABC transporter substrate-binding protein PnrA-like
NMELFEPI_01942 1.8e-148 K Helix-turn-helix domain, rpiR family
NMELFEPI_01943 6.6e-169 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
NMELFEPI_01944 9.8e-150 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NMELFEPI_01945 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMELFEPI_01946 3.9e-131 S membrane transporter protein
NMELFEPI_01947 3.9e-156 yeaE S Aldo/keto reductase family
NMELFEPI_01948 2.3e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NMELFEPI_01949 1.4e-118 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NMELFEPI_01950 1.5e-121 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NMELFEPI_01951 4.6e-230 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NMELFEPI_01952 6.7e-232 pbuG S permease
NMELFEPI_01953 6.5e-112 K helix_turn_helix, mercury resistance
NMELFEPI_01954 5.7e-231 pbuG S permease
NMELFEPI_01955 2.1e-225 pbuG S permease
NMELFEPI_01956 3e-76 K Bacteriophage CI repressor helix-turn-helix domain
NMELFEPI_01957 1.4e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NMELFEPI_01958 2.1e-86
NMELFEPI_01959 7.6e-92
NMELFEPI_01960 7.3e-74 atkY K Penicillinase repressor
NMELFEPI_01961 1.6e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NMELFEPI_01962 2.2e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NMELFEPI_01963 0.0 copA 3.6.3.54 P P-type ATPase
NMELFEPI_01964 3.4e-280 E Amino acid permease
NMELFEPI_01965 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NMELFEPI_01966 9.4e-247 ynbB 4.4.1.1 P aluminum resistance
NMELFEPI_01967 5.1e-69 K Acetyltransferase (GNAT) domain
NMELFEPI_01968 2.1e-230 EGP Sugar (and other) transporter
NMELFEPI_01969 5.1e-69 S Iron-sulphur cluster biosynthesis
NMELFEPI_01970 3.2e-11 S RelB antitoxin
NMELFEPI_01971 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NMELFEPI_01972 1.6e-288 clcA P chloride
NMELFEPI_01973 6e-271 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NMELFEPI_01974 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NMELFEPI_01975 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NMELFEPI_01976 2.8e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NMELFEPI_01977 1.6e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMELFEPI_01978 2.5e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NMELFEPI_01979 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NMELFEPI_01981 1.6e-15 L Transposase DDE domain
NMELFEPI_01982 4.7e-213 L Transposase DDE domain
NMELFEPI_01983 7.7e-09 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NMELFEPI_01984 8.7e-64 tipA K TipAS antibiotic-recognition domain
NMELFEPI_01985 2.4e-41 tipA K TipAS antibiotic-recognition domain
NMELFEPI_01986 2.7e-73 L Transposase DDE domain
NMELFEPI_01987 2.3e-159 L Transposase DDE domain
NMELFEPI_01988 3.5e-09 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NMELFEPI_01989 1.1e-125 tipA K TipAS antibiotic-recognition domain
NMELFEPI_01990 0.0 L Transposase DDE domain
NMELFEPI_01992 5.9e-77 S Fic/DOC family
NMELFEPI_01993 5.7e-142 soj D CobQ CobB MinD ParA nucleotide binding domain protein
NMELFEPI_01994 6.6e-31
NMELFEPI_01995 8.3e-54 vsr L DNA mismatch endonuclease Vsr
NMELFEPI_01996 1.8e-159 dcm 2.1.1.37 H cytosine-specific methyltransferase
NMELFEPI_01997 3.1e-104 S NgoFVII restriction endonuclease
NMELFEPI_02000 1.4e-47
NMELFEPI_02001 3.1e-48 S Lysin motif
NMELFEPI_02002 1.1e-125 L Replication initiation factor
NMELFEPI_02003 1.5e-34 L Single-strand binding protein family
NMELFEPI_02004 2.2e-91 L Phage integrase, N-terminal SAM-like domain
NMELFEPI_02005 1.8e-10 S Protein of unknown function (DUF2922)
NMELFEPI_02007 1.3e-107 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NMELFEPI_02008 7.7e-43 dhaM 2.7.1.121 S PTS system fructose IIA component
NMELFEPI_02009 4e-83 dhaL 2.7.1.121 S Dak2
NMELFEPI_02010 7.1e-157 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)