ORF_ID e_value Gene_name EC_number CAZy COGs Description
IEGPKIKM_00001 1.9e-221 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
IEGPKIKM_00002 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IEGPKIKM_00003 4.1e-234 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IEGPKIKM_00004 0.0 M Parallel beta-helix repeats
IEGPKIKM_00005 2.7e-227 M Glycosyl transferase 4-like domain
IEGPKIKM_00006 5.9e-199 ltaE 4.1.2.48 E Beta-eliminating lyase
IEGPKIKM_00008 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IEGPKIKM_00009 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IEGPKIKM_00010 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IEGPKIKM_00011 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IEGPKIKM_00012 0.0 S Esterase-like activity of phytase
IEGPKIKM_00013 1.7e-214 EGP Transmembrane secretion effector
IEGPKIKM_00015 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IEGPKIKM_00016 1.2e-94 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IEGPKIKM_00017 1e-237 carA 6.3.5.5 F Belongs to the CarA family
IEGPKIKM_00018 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
IEGPKIKM_00019 2e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
IEGPKIKM_00020 0.0 S Protein of unknown function DUF262
IEGPKIKM_00021 3.1e-116 K helix_turn_helix, Lux Regulon
IEGPKIKM_00022 8.1e-263 T Histidine kinase
IEGPKIKM_00023 1e-97 S Domain of unknown function (DUF5067)
IEGPKIKM_00024 6.6e-132 ybhL S Belongs to the BI1 family
IEGPKIKM_00025 1.3e-168 ydeD EG EamA-like transporter family
IEGPKIKM_00026 7.1e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
IEGPKIKM_00027 2.8e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IEGPKIKM_00028 3.1e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IEGPKIKM_00029 1.3e-136 fic D Fic/DOC family
IEGPKIKM_00030 0.0 ftsK D FtsK SpoIIIE family protein
IEGPKIKM_00031 3.2e-121 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEGPKIKM_00032 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
IEGPKIKM_00033 1.6e-80 K Helix-turn-helix XRE-family like proteins
IEGPKIKM_00034 1.8e-39 S Protein of unknown function (DUF3046)
IEGPKIKM_00035 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IEGPKIKM_00036 7.1e-74 recX S Modulates RecA activity
IEGPKIKM_00038 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IEGPKIKM_00039 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IEGPKIKM_00040 7.9e-191 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IEGPKIKM_00041 1.5e-109
IEGPKIKM_00042 5.1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
IEGPKIKM_00043 1.7e-180 pknL 2.7.11.1 KLT PASTA
IEGPKIKM_00044 2.2e-158 pknL 2.7.11.1 KLT PASTA
IEGPKIKM_00045 3.9e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
IEGPKIKM_00046 5e-122
IEGPKIKM_00047 3.5e-304 pepD E Peptidase family C69
IEGPKIKM_00048 0.0 S Glycosyl hydrolases related to GH101 family, GH129
IEGPKIKM_00049 1.5e-197 XK27_01805 M Glycosyltransferase like family 2
IEGPKIKM_00050 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
IEGPKIKM_00052 6.2e-203 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IEGPKIKM_00053 3.4e-220 amt U Ammonium Transporter Family
IEGPKIKM_00054 1e-54 glnB K Nitrogen regulatory protein P-II
IEGPKIKM_00055 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
IEGPKIKM_00056 3.5e-250 dinF V MatE
IEGPKIKM_00057 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IEGPKIKM_00058 3e-279 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
IEGPKIKM_00059 1.7e-142 cobQ S CobB/CobQ-like glutamine amidotransferase domain
IEGPKIKM_00060 3.5e-19 S granule-associated protein
IEGPKIKM_00061 0.0 ubiB S ABC1 family
IEGPKIKM_00062 0.0 pacS 3.6.3.54 P E1-E2 ATPase
IEGPKIKM_00063 9.6e-43 csoR S Metal-sensitive transcriptional repressor
IEGPKIKM_00064 1.3e-214 rmuC S RmuC family
IEGPKIKM_00065 2.7e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IEGPKIKM_00066 2.2e-154 spoU 2.1.1.185 J RNA methyltransferase TrmH family
IEGPKIKM_00067 3.3e-59 V ABC transporter
IEGPKIKM_00068 9e-63 V ABC transporter
IEGPKIKM_00069 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEGPKIKM_00070 6.4e-290 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IEGPKIKM_00071 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEGPKIKM_00072 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
IEGPKIKM_00073 3.3e-52 S Protein of unknown function (DUF2469)
IEGPKIKM_00074 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
IEGPKIKM_00075 1.2e-304 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IEGPKIKM_00076 3e-234 E Aminotransferase class I and II
IEGPKIKM_00077 1.5e-89 lrp_3 K helix_turn_helix ASNC type
IEGPKIKM_00078 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
IEGPKIKM_00079 1.6e-52 K Putative ATP-dependent DNA helicase recG C-terminal
IEGPKIKM_00080 2.7e-160 K Helix-turn-helix domain, rpiR family
IEGPKIKM_00081 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IEGPKIKM_00082 2.3e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
IEGPKIKM_00083 1.1e-129 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IEGPKIKM_00084 1.6e-140 guaB 1.1.1.205 F IMP dehydrogenase family protein
IEGPKIKM_00085 3.4e-91
IEGPKIKM_00086 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
IEGPKIKM_00087 5.8e-88 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IEGPKIKM_00088 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
IEGPKIKM_00089 7e-90 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IEGPKIKM_00090 2.4e-92 S Aminoacyl-tRNA editing domain
IEGPKIKM_00091 6.8e-63 K helix_turn_helix, Lux Regulon
IEGPKIKM_00092 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IEGPKIKM_00093 2.1e-263 hisS 6.1.1.21 J Histidyl-tRNA synthetase
IEGPKIKM_00094 4.4e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IEGPKIKM_00095 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IEGPKIKM_00096 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
IEGPKIKM_00097 4.3e-190
IEGPKIKM_00099 6.9e-201
IEGPKIKM_00101 5.5e-122 mgtC S MgtC family
IEGPKIKM_00102 1.8e-40 S Protein of unknown function (DUF2442)
IEGPKIKM_00103 1.6e-61 S Bacterial mobilisation protein (MobC)
IEGPKIKM_00104 2.1e-299 ltrBE1 U Relaxase/Mobilisation nuclease domain
IEGPKIKM_00105 5.5e-168 S Protein of unknown function (DUF3801)
IEGPKIKM_00106 2.5e-53 3.6.1.13 L NUDIX domain
IEGPKIKM_00107 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
IEGPKIKM_00108 7.9e-219 ykiI
IEGPKIKM_00109 2.8e-174 L Transposase and inactivated derivatives IS30 family
IEGPKIKM_00110 1.9e-25 K Putative ATP-dependent DNA helicase recG C-terminal
IEGPKIKM_00111 2.4e-44 S Memo-like protein
IEGPKIKM_00113 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IEGPKIKM_00114 2.9e-179 adh3 C Zinc-binding dehydrogenase
IEGPKIKM_00115 3.3e-132 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IEGPKIKM_00116 4.5e-79 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
IEGPKIKM_00117 3.4e-15
IEGPKIKM_00118 1.7e-120 K helix_turn_helix, Lux Regulon
IEGPKIKM_00119 5.2e-08 3.4.22.70 M Sortase family
IEGPKIKM_00120 3.3e-255 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IEGPKIKM_00121 4e-77 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
IEGPKIKM_00122 1.8e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEGPKIKM_00123 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEGPKIKM_00124 3.4e-73 nrdI F Probably involved in ribonucleotide reductase function
IEGPKIKM_00125 0.0 S Predicted membrane protein (DUF2207)
IEGPKIKM_00126 3.7e-94 lemA S LemA family
IEGPKIKM_00127 8e-115 xylR K purine nucleotide biosynthetic process
IEGPKIKM_00128 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IEGPKIKM_00129 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IEGPKIKM_00130 4e-119
IEGPKIKM_00131 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
IEGPKIKM_00132 6.1e-45 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
IEGPKIKM_00133 3.4e-63 S Bacterial PH domain
IEGPKIKM_00135 6.2e-56
IEGPKIKM_00138 8.8e-82 sppA OU Serine dehydrogenase proteinase
IEGPKIKM_00140 2.2e-134 int L Phage integrase, N-terminal SAM-like domain
IEGPKIKM_00142 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
IEGPKIKM_00143 1.1e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IEGPKIKM_00144 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
IEGPKIKM_00145 7.2e-308 pccB I Carboxyl transferase domain
IEGPKIKM_00146 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
IEGPKIKM_00147 4.2e-93 bioY S BioY family
IEGPKIKM_00148 1.1e-150 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
IEGPKIKM_00149 0.0
IEGPKIKM_00150 5.9e-146 QT PucR C-terminal helix-turn-helix domain
IEGPKIKM_00151 4.5e-39 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IEGPKIKM_00152 2.6e-87 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IEGPKIKM_00153 1.5e-67 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IEGPKIKM_00155 3.8e-218 U Type IV secretory system Conjugative DNA transfer
IEGPKIKM_00156 9.3e-31
IEGPKIKM_00157 3.2e-39
IEGPKIKM_00158 1e-154
IEGPKIKM_00160 1.1e-87
IEGPKIKM_00161 2.7e-213 S Phage portal protein, SPP1 Gp6-like
IEGPKIKM_00162 2.9e-216 S Terminase
IEGPKIKM_00163 9.2e-60 U Sodium:dicarboxylate symporter family
IEGPKIKM_00164 1.1e-47 U Sodium:dicarboxylate symporter family
IEGPKIKM_00165 0.0
IEGPKIKM_00167 3.2e-81
IEGPKIKM_00168 2.2e-59
IEGPKIKM_00169 3.8e-47
IEGPKIKM_00170 2.3e-227 S HipA-like C-terminal domain
IEGPKIKM_00171 3.4e-97
IEGPKIKM_00172 1.8e-19
IEGPKIKM_00173 6.1e-20 XK27_00515 D Cell surface antigen C-terminus
IEGPKIKM_00174 7.6e-22 D Cell surface antigen C-terminus
IEGPKIKM_00175 1e-26 XK27_00515 D Cell surface antigen C-terminus
IEGPKIKM_00176 2.7e-37 XK27_00515 D Cell surface antigen C-terminus
IEGPKIKM_00177 2e-15
IEGPKIKM_00178 5.3e-39 sprF 4.6.1.1 M Cell surface antigen C-terminus
IEGPKIKM_00179 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IEGPKIKM_00181 8.6e-190 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
IEGPKIKM_00182 8.3e-157 L Tetratricopeptide repeat
IEGPKIKM_00184 2.3e-278 aspA 4.3.1.1 E Fumarase C C-terminus
IEGPKIKM_00185 3.4e-267 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
IEGPKIKM_00186 8.1e-31 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IEGPKIKM_00187 5.1e-171 S Auxin Efflux Carrier
IEGPKIKM_00190 0.0 pgi 5.3.1.9 G Belongs to the GPI family
IEGPKIKM_00191 3.2e-276 G ABC transporter substrate-binding protein
IEGPKIKM_00192 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
IEGPKIKM_00193 7.8e-299 S ATPases associated with a variety of cellular activities
IEGPKIKM_00194 1.2e-55 EGP Major facilitator Superfamily
IEGPKIKM_00195 5.7e-146 I alpha/beta hydrolase fold
IEGPKIKM_00196 3.6e-114 S Pyridoxamine 5'-phosphate oxidase
IEGPKIKM_00198 1.3e-55 S DUF218 domain
IEGPKIKM_00199 6.2e-39 S Protein of unknown function (DUF979)
IEGPKIKM_00200 5.7e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IEGPKIKM_00202 5.7e-126
IEGPKIKM_00203 6.5e-162 M domain, Protein
IEGPKIKM_00204 4e-19 M domain, Protein
IEGPKIKM_00205 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
IEGPKIKM_00206 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
IEGPKIKM_00207 7.1e-172 tesB I Thioesterase-like superfamily
IEGPKIKM_00208 1.3e-77 S Protein of unknown function (DUF3180)
IEGPKIKM_00209 3e-292 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IEGPKIKM_00210 2.3e-164 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IEGPKIKM_00211 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
IEGPKIKM_00212 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IEGPKIKM_00213 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IEGPKIKM_00214 3.5e-213 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IEGPKIKM_00215 1.6e-261 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
IEGPKIKM_00216 5e-309
IEGPKIKM_00217 1.7e-168 natA V ATPases associated with a variety of cellular activities
IEGPKIKM_00218 3.7e-232 epsG M Glycosyl transferase family 21
IEGPKIKM_00219 4.6e-275 S AI-2E family transporter
IEGPKIKM_00220 4.3e-177 3.4.14.13 M Glycosyltransferase like family 2
IEGPKIKM_00221 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
IEGPKIKM_00222 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEGPKIKM_00223 1.6e-171 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
IEGPKIKM_00224 5.1e-89 pgp 3.1.3.18 S HAD-hyrolase-like
IEGPKIKM_00227 3.6e-90 K Putative zinc ribbon domain
IEGPKIKM_00228 2.1e-125 S GyrI-like small molecule binding domain
IEGPKIKM_00229 5.7e-24 L DNA integration
IEGPKIKM_00230 1.2e-152 yeaZ 2.3.1.234 O Glycoprotease family
IEGPKIKM_00231 5e-102 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
IEGPKIKM_00232 6.2e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IEGPKIKM_00234 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IEGPKIKM_00235 5e-246
IEGPKIKM_00236 2.3e-41 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IEGPKIKM_00237 3e-55
IEGPKIKM_00238 4.8e-108
IEGPKIKM_00239 6.8e-220 topB 5.99.1.2 L DNA topoisomerase
IEGPKIKM_00240 6.5e-139 topB 5.99.1.2 L DNA topoisomerase
IEGPKIKM_00241 1.1e-95 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEGPKIKM_00242 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEGPKIKM_00243 8e-171 S Endonuclease/Exonuclease/phosphatase family
IEGPKIKM_00245 0.0 fadD 6.2.1.3 I AMP-binding enzyme
IEGPKIKM_00246 2.1e-42 K Transcriptional regulator
IEGPKIKM_00247 2.5e-265 EGP Major Facilitator Superfamily
IEGPKIKM_00248 3.2e-116
IEGPKIKM_00249 1.9e-30 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
IEGPKIKM_00250 1.2e-174 K Psort location Cytoplasmic, score
IEGPKIKM_00251 2.6e-55 KLT Protein tyrosine kinase
IEGPKIKM_00252 6.3e-32
IEGPKIKM_00253 3e-146 V Phage capsid family
IEGPKIKM_00255 3e-46 S Phage protein Gp19/Gp15/Gp42
IEGPKIKM_00256 1e-30
IEGPKIKM_00258 1.5e-66 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
IEGPKIKM_00259 8.8e-300 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
IEGPKIKM_00260 2.8e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEGPKIKM_00261 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IEGPKIKM_00262 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IEGPKIKM_00263 2.1e-42 yggT S YGGT family
IEGPKIKM_00264 9.7e-90 3.1.21.3 V DivIVA protein
IEGPKIKM_00265 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IEGPKIKM_00266 3.4e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IEGPKIKM_00268 1.7e-62
IEGPKIKM_00269 2.6e-146 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
IEGPKIKM_00270 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IEGPKIKM_00271 5.9e-197 ftsE D Cell division ATP-binding protein FtsE
IEGPKIKM_00272 2.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
IEGPKIKM_00273 4.6e-168 usp 3.5.1.28 CBM50 D CHAP domain protein
IEGPKIKM_00274 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IEGPKIKM_00275 1e-147 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
IEGPKIKM_00276 1.7e-81
IEGPKIKM_00278 1.6e-203 2.7.11.1 NU Tfp pilus assembly protein FimV
IEGPKIKM_00279 5.2e-223 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IEGPKIKM_00280 3.9e-235 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IEGPKIKM_00281 1.2e-291 I acetylesterase activity
IEGPKIKM_00282 6.6e-142 recO L Involved in DNA repair and RecF pathway recombination
IEGPKIKM_00283 1.5e-154 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IEGPKIKM_00284 5.1e-192 ywqG S Domain of unknown function (DUF1963)
IEGPKIKM_00285 1.7e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
IEGPKIKM_00286 8.8e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
IEGPKIKM_00287 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
IEGPKIKM_00288 7.6e-106 S zinc-ribbon domain
IEGPKIKM_00289 4.6e-143 S Putative ABC-transporter type IV
IEGPKIKM_00290 7.2e-109 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IEGPKIKM_00291 3.4e-191 argH 4.3.2.1 E argininosuccinate lyase
IEGPKIKM_00292 1e-07
IEGPKIKM_00293 9.2e-38 L HNH endonuclease
IEGPKIKM_00296 2.9e-18
IEGPKIKM_00299 1.6e-57 M Peptidase family M23
IEGPKIKM_00300 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
IEGPKIKM_00301 5.5e-36 lhr L DEAD DEAH box helicase
IEGPKIKM_00302 3e-25 yozG K Cro/C1-type HTH DNA-binding domain
IEGPKIKM_00303 3.3e-59 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
IEGPKIKM_00304 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IEGPKIKM_00305 2.8e-123 pip 3.4.11.5 S alpha/beta hydrolase fold
IEGPKIKM_00306 5.4e-90 argH 4.3.2.1 E argininosuccinate lyase
IEGPKIKM_00307 7.7e-274 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IEGPKIKM_00308 5.7e-30
IEGPKIKM_00309 1.8e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IEGPKIKM_00310 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IEGPKIKM_00311 9.1e-99 clcA_2 P Voltage gated chloride channel
IEGPKIKM_00312 1.9e-68 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IEGPKIKM_00313 5.5e-242 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IEGPKIKM_00314 5.8e-164 EP Binding-protein-dependent transport system inner membrane component
IEGPKIKM_00315 9.8e-158 P Binding-protein-dependent transport system inner membrane component
IEGPKIKM_00316 1.6e-35 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
IEGPKIKM_00317 4.3e-26 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
IEGPKIKM_00318 3.2e-147 P NLPA lipoprotein
IEGPKIKM_00319 6.5e-187 acoA 1.2.4.1 C Dehydrogenase E1 component
IEGPKIKM_00320 6.6e-182 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
IEGPKIKM_00321 2.6e-203 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEGPKIKM_00322 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
IEGPKIKM_00323 6.4e-229 mtnE 2.6.1.83 E Aminotransferase class I and II
IEGPKIKM_00324 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IEGPKIKM_00325 1.3e-243 XK27_00240 K Fic/DOC family
IEGPKIKM_00326 3e-120 E Psort location Cytoplasmic, score 8.87
IEGPKIKM_00327 5.6e-59 yccF S Inner membrane component domain
IEGPKIKM_00328 3.6e-157 ksgA 2.1.1.182 J Methyltransferase domain
IEGPKIKM_00329 2.6e-63 S Cupin 2, conserved barrel domain protein
IEGPKIKM_00330 4.1e-258 KLT Protein tyrosine kinase
IEGPKIKM_00331 4.5e-79 K Psort location Cytoplasmic, score
IEGPKIKM_00332 5.3e-149
IEGPKIKM_00333 2.7e-22
IEGPKIKM_00334 1e-197 S Short C-terminal domain
IEGPKIKM_00335 2.7e-87 S Helix-turn-helix
IEGPKIKM_00336 1.1e-65 S Zincin-like metallopeptidase
IEGPKIKM_00337 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
IEGPKIKM_00338 2.5e-24
IEGPKIKM_00339 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IEGPKIKM_00340 1.2e-125 ypfH S Phospholipase/Carboxylesterase
IEGPKIKM_00341 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
IEGPKIKM_00343 2.2e-290 2.4.1.166 GT2 M Glycosyltransferase like family 2
IEGPKIKM_00344 1.4e-118 3.1.3.27 E haloacid dehalogenase-like hydrolase
IEGPKIKM_00345 2.3e-145 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
IEGPKIKM_00346 3.2e-187 MA20_14895 S Conserved hypothetical protein 698
IEGPKIKM_00347 2.3e-63 S Phospholipase/Carboxylesterase
IEGPKIKM_00348 7.1e-57 3.1.3.73 G Phosphoglycerate mutase family
IEGPKIKM_00350 2.9e-234 patB 4.4.1.8 E Aminotransferase, class I II
IEGPKIKM_00351 2.6e-106 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
IEGPKIKM_00352 3.7e-154 sapF E ATPases associated with a variety of cellular activities
IEGPKIKM_00353 4.9e-30 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEGPKIKM_00354 1.2e-33 argR K Regulates arginine biosynthesis genes
IEGPKIKM_00355 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IEGPKIKM_00356 9.7e-95 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
IEGPKIKM_00357 1.1e-112 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEGPKIKM_00358 1.1e-112 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IEGPKIKM_00359 6.3e-44 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IEGPKIKM_00361 5.6e-79 M Belongs to the glycosyl hydrolase 28 family
IEGPKIKM_00362 4.2e-233 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
IEGPKIKM_00363 4.3e-73 MA20_36090 S Psort location Cytoplasmic, score 8.87
IEGPKIKM_00364 1.7e-119 K Bacterial regulatory proteins, tetR family
IEGPKIKM_00365 2.1e-132 M Mechanosensitive ion channel
IEGPKIKM_00366 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IEGPKIKM_00367 4.3e-30 2.1.1.72 S Protein conserved in bacteria
IEGPKIKM_00368 2.4e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
IEGPKIKM_00369 1.6e-66 S Domain of unknown function (DUF4854)
IEGPKIKM_00370 1.1e-212 3.4.22.70 M Sortase family
IEGPKIKM_00371 2.8e-288 M LPXTG cell wall anchor motif
IEGPKIKM_00372 0.0 inlJ M domain protein
IEGPKIKM_00373 7.1e-76 inlJ M domain protein
IEGPKIKM_00374 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
IEGPKIKM_00375 2.2e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IEGPKIKM_00376 5.4e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
IEGPKIKM_00377 1.3e-129 M Protein of unknown function (DUF3152)
IEGPKIKM_00378 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
IEGPKIKM_00380 6.1e-67 E Domain of unknown function (DUF5011)
IEGPKIKM_00381 7.7e-35 S Parallel beta-helix repeats
IEGPKIKM_00382 6.6e-70 rplI J Binds to the 23S rRNA
IEGPKIKM_00383 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IEGPKIKM_00384 2.8e-75 ssb1 L Single-stranded DNA-binding protein
IEGPKIKM_00385 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
IEGPKIKM_00386 1.3e-162 T Pfam Adenylate and Guanylate cyclase catalytic domain
IEGPKIKM_00387 4e-114
IEGPKIKM_00388 2.4e-170
IEGPKIKM_00389 1.6e-120 L Single-strand binding protein family
IEGPKIKM_00390 0.0 pepO 3.4.24.71 O Peptidase family M13
IEGPKIKM_00391 6.9e-127 S Short repeat of unknown function (DUF308)
IEGPKIKM_00392 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
IEGPKIKM_00393 3.2e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
IEGPKIKM_00394 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
IEGPKIKM_00395 8.4e-198 yghZ C Aldo/keto reductase family
IEGPKIKM_00397 0.0 ctpE P E1-E2 ATPase
IEGPKIKM_00398 3.9e-112 macB_2 V ATPases associated with a variety of cellular activities
IEGPKIKM_00399 1.8e-226 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IEGPKIKM_00400 4.7e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
IEGPKIKM_00401 5.7e-233 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
IEGPKIKM_00402 8.4e-243 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
IEGPKIKM_00403 4.9e-128 XK27_08050 O prohibitin homologues
IEGPKIKM_00404 7.1e-275 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
IEGPKIKM_00405 3.8e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IEGPKIKM_00406 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IEGPKIKM_00407 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
IEGPKIKM_00408 2.3e-244 hsdM 2.1.1.72 V HsdM N-terminal domain
IEGPKIKM_00409 1.8e-38 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEGPKIKM_00410 8.5e-226 dapC E Aminotransferase class I and II
IEGPKIKM_00411 9e-61 fdxA C 4Fe-4S binding domain
IEGPKIKM_00412 1.1e-215 murB 1.3.1.98 M Cell wall formation
IEGPKIKM_00413 1.9e-25 rpmG J Ribosomal protein L33
IEGPKIKM_00417 1.2e-51 moxR S ATPase family associated with various cellular activities (AAA)
IEGPKIKM_00418 2.1e-132 bla1 3.5.2.6 V Beta-lactamase enzyme family
IEGPKIKM_00419 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IEGPKIKM_00420 6.3e-148
IEGPKIKM_00421 2e-93 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
IEGPKIKM_00422 2.4e-84 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
IEGPKIKM_00423 3.2e-38 fmdB S Putative regulatory protein
IEGPKIKM_00424 5.6e-110 flgA NO SAF
IEGPKIKM_00425 9.6e-42
IEGPKIKM_00426 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
IEGPKIKM_00427 2.1e-238 T Forkhead associated domain
IEGPKIKM_00429 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IEGPKIKM_00430 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IEGPKIKM_00431 5.6e-186 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
IEGPKIKM_00434 3.9e-21 pbuO S Permease family
IEGPKIKM_00435 6.3e-189 pbuO S Permease family
IEGPKIKM_00436 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
IEGPKIKM_00437 7e-161 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
IEGPKIKM_00438 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IEGPKIKM_00439 6.2e-180 pstA P Phosphate transport system permease
IEGPKIKM_00440 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
IEGPKIKM_00441 3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
IEGPKIKM_00442 1.3e-128 KT Transcriptional regulatory protein, C terminal
IEGPKIKM_00443 1.4e-245 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
IEGPKIKM_00444 1.2e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IEGPKIKM_00445 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IEGPKIKM_00446 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
IEGPKIKM_00447 0.0 helY L DEAD DEAH box helicase
IEGPKIKM_00448 1e-51
IEGPKIKM_00449 0.0 pafB K WYL domain
IEGPKIKM_00450 2e-288 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
IEGPKIKM_00452 1.3e-90 dkgB S Oxidoreductase, aldo keto reductase family protein
IEGPKIKM_00453 5.8e-143 4.1.1.44 S Carboxymuconolactone decarboxylase family
IEGPKIKM_00454 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IEGPKIKM_00455 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IEGPKIKM_00456 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
IEGPKIKM_00457 2.1e-85 T Domain of unknown function (DUF4234)
IEGPKIKM_00458 1.9e-101 K Bacterial regulatory proteins, tetR family
IEGPKIKM_00459 5.4e-19
IEGPKIKM_00460 3.4e-48 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
IEGPKIKM_00461 3.7e-41 K Helix-turn-helix
IEGPKIKM_00462 7e-225 hipA 2.7.11.1 S HipA N-terminal domain
IEGPKIKM_00463 2.4e-65 4.1.1.44 S Cupin domain
IEGPKIKM_00464 1.8e-176 S Membrane transport protein
IEGPKIKM_00465 1e-93 laaE K Transcriptional regulator PadR-like family
IEGPKIKM_00466 2.3e-133 magIII L endonuclease III
IEGPKIKM_00467 1.6e-131 S Enoyl-(Acyl carrier protein) reductase
IEGPKIKM_00468 5.2e-243 vbsD V MatE
IEGPKIKM_00469 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IEGPKIKM_00470 1.9e-15 KLT Protein tyrosine kinase
IEGPKIKM_00471 5.3e-140
IEGPKIKM_00472 9e-195 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
IEGPKIKM_00473 1.9e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IEGPKIKM_00474 9.6e-180 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IEGPKIKM_00475 1.7e-156 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
IEGPKIKM_00476 3.2e-26 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
IEGPKIKM_00477 3.1e-33 L Transposase and inactivated derivatives IS30 family
IEGPKIKM_00478 7.1e-200 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IEGPKIKM_00479 1.4e-88 S Fic/DOC family
IEGPKIKM_00480 1.2e-32 S Fic/DOC family
IEGPKIKM_00481 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IEGPKIKM_00482 5e-38 ptsH G PTS HPr component phosphorylation site
IEGPKIKM_00483 4.4e-200 K helix_turn _helix lactose operon repressor
IEGPKIKM_00484 3.5e-211 holB 2.7.7.7 L DNA polymerase III
IEGPKIKM_00485 1.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IEGPKIKM_00486 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IEGPKIKM_00487 3e-188 3.6.1.27 I PAP2 superfamily
IEGPKIKM_00488 0.0 vpr M PA domain
IEGPKIKM_00489 4e-122 yplQ S Haemolysin-III related
IEGPKIKM_00490 7.1e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
IEGPKIKM_00491 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
IEGPKIKM_00492 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IEGPKIKM_00493 3.5e-279 S Calcineurin-like phosphoesterase
IEGPKIKM_00494 3e-15 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
IEGPKIKM_00495 2.4e-284 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
IEGPKIKM_00496 1.7e-116
IEGPKIKM_00497 4e-181 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
IEGPKIKM_00498 1.3e-254 cdr OP Sulfurtransferase TusA
IEGPKIKM_00499 2.6e-149 moeB 2.7.7.80 H ThiF family
IEGPKIKM_00500 5.4e-133 tmp1 S Domain of unknown function (DUF4391)
IEGPKIKM_00501 7.6e-49 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
IEGPKIKM_00502 2.9e-229 aspB E Aminotransferase class-V
IEGPKIKM_00503 1.5e-88 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
IEGPKIKM_00504 9.1e-267 S zinc finger
IEGPKIKM_00505 8.8e-124 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IEGPKIKM_00506 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IEGPKIKM_00507 6.7e-293 O Subtilase family
IEGPKIKM_00508 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
IEGPKIKM_00509 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEGPKIKM_00510 8.5e-162 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEGPKIKM_00511 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IEGPKIKM_00512 5.5e-35 L Transposase
IEGPKIKM_00513 6.4e-24 relB L RelB antitoxin
IEGPKIKM_00514 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
IEGPKIKM_00515 2.9e-66 gsiA P ATPase activity
IEGPKIKM_00516 1.3e-257 G Major Facilitator Superfamily
IEGPKIKM_00517 8.6e-159 K -acetyltransferase
IEGPKIKM_00518 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
IEGPKIKM_00519 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
IEGPKIKM_00520 1.3e-268 KLT Protein tyrosine kinase
IEGPKIKM_00521 0.0 S Fibronectin type 3 domain
IEGPKIKM_00522 2.8e-220 S ATPase family associated with various cellular activities (AAA)
IEGPKIKM_00523 1.5e-226 S Protein of unknown function DUF58
IEGPKIKM_00524 0.0 E Transglutaminase-like superfamily
IEGPKIKM_00525 3.4e-166 3.1.3.16 T Sigma factor PP2C-like phosphatases
IEGPKIKM_00526 2.8e-68 B Belongs to the OprB family
IEGPKIKM_00527 7.2e-95 T Forkhead associated domain
IEGPKIKM_00528 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEGPKIKM_00529 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEGPKIKM_00530 1.4e-105
IEGPKIKM_00531 7.3e-183 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
IEGPKIKM_00532 8.4e-36 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G xyloglucan:xyloglucosyl transferase activity
IEGPKIKM_00533 2e-64 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
IEGPKIKM_00534 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IEGPKIKM_00535 3.3e-211 ugpC E Belongs to the ABC transporter superfamily
IEGPKIKM_00536 1.2e-100 L Helix-turn-helix domain
IEGPKIKM_00537 0.0 S LPXTG-motif cell wall anchor domain protein
IEGPKIKM_00538 1.4e-250 M LPXTG-motif cell wall anchor domain protein
IEGPKIKM_00539 4.5e-180 3.4.22.70 M Sortase family
IEGPKIKM_00540 3.7e-154
IEGPKIKM_00541 1e-270 KLT Domain of unknown function (DUF4032)
IEGPKIKM_00542 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEGPKIKM_00544 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
IEGPKIKM_00545 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
IEGPKIKM_00546 1.2e-111 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
IEGPKIKM_00547 0.0 yjcE P Sodium/hydrogen exchanger family
IEGPKIKM_00548 1.2e-145 ypfH S Phospholipase/Carboxylesterase
IEGPKIKM_00549 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IEGPKIKM_00550 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
IEGPKIKM_00551 3e-144 cobB2 K Sir2 family
IEGPKIKM_00552 5.6e-208 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
IEGPKIKM_00553 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IEGPKIKM_00554 3.6e-82
IEGPKIKM_00555 5.1e-245 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
IEGPKIKM_00556 8e-182 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
IEGPKIKM_00557 4.5e-158 ybeM S Carbon-nitrogen hydrolase
IEGPKIKM_00558 1.9e-49 S Sel1-like repeats.
IEGPKIKM_00559 2.9e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IEGPKIKM_00560 1.9e-181 L Transposase
IEGPKIKM_00561 1.6e-28
IEGPKIKM_00562 9.2e-271 L Uncharacterized conserved protein (DUF2075)
IEGPKIKM_00563 8.6e-30
IEGPKIKM_00564 8.3e-81 rarD 3.4.17.13 E Rard protein
IEGPKIKM_00565 1.4e-23 rarD S EamA-like transporter family
IEGPKIKM_00566 8.8e-178 I alpha/beta hydrolase fold
IEGPKIKM_00567 7.4e-208 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IEGPKIKM_00568 1.2e-100 sixA T Phosphoglycerate mutase family
IEGPKIKM_00569 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IEGPKIKM_00570 1.6e-162 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
IEGPKIKM_00572 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
IEGPKIKM_00573 2.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IEGPKIKM_00574 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
IEGPKIKM_00575 3.8e-281 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IEGPKIKM_00576 1.5e-133 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
IEGPKIKM_00578 1.9e-72
IEGPKIKM_00579 4.7e-252 S UPF0210 protein
IEGPKIKM_00580 4.2e-43 gcvR T Belongs to the UPF0237 family
IEGPKIKM_00581 8.6e-243 EGP Sugar (and other) transporter
IEGPKIKM_00582 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
IEGPKIKM_00583 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
IEGPKIKM_00584 3.1e-139 glpR K DeoR C terminal sensor domain
IEGPKIKM_00585 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
IEGPKIKM_00586 1.9e-219 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
IEGPKIKM_00587 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
IEGPKIKM_00588 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
IEGPKIKM_00589 9.9e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
IEGPKIKM_00590 4.5e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IEGPKIKM_00591 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
IEGPKIKM_00592 3.4e-239 S Uncharacterized conserved protein (DUF2183)
IEGPKIKM_00593 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
IEGPKIKM_00594 0.0 enhA_2 S L,D-transpeptidase catalytic domain
IEGPKIKM_00595 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
IEGPKIKM_00596 3.1e-161 mhpC I Alpha/beta hydrolase family
IEGPKIKM_00597 2.8e-119 F Domain of unknown function (DUF4916)
IEGPKIKM_00598 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
IEGPKIKM_00599 1.3e-179 S G5
IEGPKIKM_00600 7.4e-219 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
IEGPKIKM_00601 0.0 S Lysylphosphatidylglycerol synthase TM region
IEGPKIKM_00602 8.1e-42 hup L Belongs to the bacterial histone-like protein family
IEGPKIKM_00603 3.6e-274 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IEGPKIKM_00604 3.8e-09 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
IEGPKIKM_00605 2.4e-158 hisN 3.1.3.25 G Inositol monophosphatase family
IEGPKIKM_00606 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
IEGPKIKM_00607 0.0 arc O AAA ATPase forming ring-shaped complexes
IEGPKIKM_00608 4.7e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
IEGPKIKM_00609 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IEGPKIKM_00610 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IEGPKIKM_00611 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEGPKIKM_00612 1.7e-61 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEGPKIKM_00613 8.5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IEGPKIKM_00614 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IEGPKIKM_00615 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
IEGPKIKM_00616 9.4e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
IEGPKIKM_00617 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IEGPKIKM_00618 0.0 ctpE P E1-E2 ATPase
IEGPKIKM_00619 8.3e-108
IEGPKIKM_00620 2.8e-162 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEGPKIKM_00621 1.4e-234 S domain protein
IEGPKIKM_00622 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IEGPKIKM_00623 2.8e-293 E Bacterial extracellular solute-binding proteins, family 5 Middle
IEGPKIKM_00624 2.5e-126 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IEGPKIKM_00625 1.8e-133 KT Transcriptional regulatory protein, C terminal
IEGPKIKM_00626 1.4e-125
IEGPKIKM_00627 2.7e-100 mntP P Probably functions as a manganese efflux pump
IEGPKIKM_00629 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IEGPKIKM_00630 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
IEGPKIKM_00631 0.0 K RNA polymerase II activating transcription factor binding
IEGPKIKM_00632 1.1e-38
IEGPKIKM_00635 6.2e-07 K BetR domain
IEGPKIKM_00637 1.6e-38 O prohibitin homologues
IEGPKIKM_00641 3.4e-13 ssb1 L Single-stranded DNA-binding protein
IEGPKIKM_00642 7e-08
IEGPKIKM_00643 2.6e-11
IEGPKIKM_00644 2.2e-32 V HNH endonuclease
IEGPKIKM_00645 3.7e-137 KL DEAD-like helicases superfamily
IEGPKIKM_00646 7.2e-95 L N-4 methylation of cytosine
IEGPKIKM_00647 1.7e-63 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
IEGPKIKM_00653 3e-08
IEGPKIKM_00656 0.0 S Uncharacterised protein family (UPF0182)
IEGPKIKM_00657 6.2e-207 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IEGPKIKM_00658 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IEGPKIKM_00659 2.4e-220 I transferase activity, transferring acyl groups other than amino-acyl groups
IEGPKIKM_00662 1.8e-130 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IEGPKIKM_00663 2.1e-196 GM GDP-mannose 4,6 dehydratase
IEGPKIKM_00664 3.6e-151 GM ABC-2 type transporter
IEGPKIKM_00665 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
IEGPKIKM_00666 1.7e-96 2.3.1.183 M Acetyltransferase (GNAT) domain
IEGPKIKM_00667 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IEGPKIKM_00668 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IEGPKIKM_00669 6.9e-297 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
IEGPKIKM_00670 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
IEGPKIKM_00671 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IEGPKIKM_00672 2.5e-101 divIC D Septum formation initiator
IEGPKIKM_00673 2e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
IEGPKIKM_00674 8.9e-184 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
IEGPKIKM_00676 1.6e-97
IEGPKIKM_00677 1.4e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
IEGPKIKM_00678 3.5e-146 KT RESPONSE REGULATOR receiver
IEGPKIKM_00679 3.7e-193 V VanZ like family
IEGPKIKM_00680 3.9e-110 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
IEGPKIKM_00681 8.6e-96 ypjC S Putative ABC-transporter type IV
IEGPKIKM_00682 4e-159
IEGPKIKM_00684 3.4e-118 EGP Major facilitator Superfamily
IEGPKIKM_00685 1.3e-163 rpoC M heme binding
IEGPKIKM_00686 1.6e-79 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEGPKIKM_00687 1.8e-122
IEGPKIKM_00688 1.9e-132 S SOS response associated peptidase (SRAP)
IEGPKIKM_00689 7.7e-185 S Acetyltransferase (GNAT) domain
IEGPKIKM_00691 1.2e-19 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
IEGPKIKM_00692 6.9e-37 2.7.7.1, 3.6.1.13, 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
IEGPKIKM_00693 6.9e-11 K Transcriptional regulator
IEGPKIKM_00694 2.9e-42 K Transcriptional regulator
IEGPKIKM_00695 1.4e-89 MA20_25245 K FR47-like protein
IEGPKIKM_00696 1.2e-120 ydaF_1 J Acetyltransferase (GNAT) domain
IEGPKIKM_00697 7.6e-64 yeaO K Protein of unknown function, DUF488
IEGPKIKM_00698 9e-161 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IEGPKIKM_00699 8.8e-284 S Psort location Cytoplasmic, score 8.87
IEGPKIKM_00700 1.7e-108 S Domain of unknown function (DUF4194)
IEGPKIKM_00701 0.0 S Psort location Cytoplasmic, score 8.87
IEGPKIKM_00702 7e-300 E Serine carboxypeptidase
IEGPKIKM_00703 3.6e-162 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IEGPKIKM_00704 3.7e-171 corA P CorA-like Mg2+ transporter protein
IEGPKIKM_00705 1e-45 ET Bacterial periplasmic substrate-binding proteins
IEGPKIKM_00706 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
IEGPKIKM_00707 2.5e-214 I Diacylglycerol kinase catalytic domain
IEGPKIKM_00708 7.6e-152 arbG K CAT RNA binding domain
IEGPKIKM_00709 0.0 crr G pts system, glucose-specific IIABC component
IEGPKIKM_00710 5e-26 M Spy0128-like isopeptide containing domain
IEGPKIKM_00711 1.7e-67 M Spy0128-like isopeptide containing domain
IEGPKIKM_00712 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
IEGPKIKM_00713 3.1e-262 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEGPKIKM_00714 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
IEGPKIKM_00715 3.8e-204 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEGPKIKM_00716 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IEGPKIKM_00718 1.2e-106
IEGPKIKM_00719 1.6e-155 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IEGPKIKM_00720 7e-69 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IEGPKIKM_00721 6.9e-234 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
IEGPKIKM_00722 6.8e-116 trkA P TrkA-N domain
IEGPKIKM_00723 3.9e-236 trkB P Cation transport protein
IEGPKIKM_00724 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IEGPKIKM_00725 2.9e-294 recN L May be involved in recombinational repair of damaged DNA
IEGPKIKM_00726 3.4e-123 S Haloacid dehalogenase-like hydrolase
IEGPKIKM_00727 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
IEGPKIKM_00728 7.7e-177 V ATPases associated with a variety of cellular activities
IEGPKIKM_00729 1.2e-124 S ABC-2 family transporter protein
IEGPKIKM_00730 2.8e-123 S ABC-2 family transporter protein
IEGPKIKM_00731 2.3e-284 thrC 4.2.3.1 E Threonine synthase N terminus
IEGPKIKM_00732 1e-235 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IEGPKIKM_00733 1.3e-91
IEGPKIKM_00734 1.6e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IEGPKIKM_00735 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEGPKIKM_00737 9.2e-264 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IEGPKIKM_00738 2.4e-69 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IEGPKIKM_00739 4.2e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IEGPKIKM_00740 1.3e-78 S Bacterial PH domain
IEGPKIKM_00741 7.1e-255 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
IEGPKIKM_00743 1.4e-93
IEGPKIKM_00744 5e-133 C Putative TM nitroreductase
IEGPKIKM_00745 3.1e-143 yijF S Domain of unknown function (DUF1287)
IEGPKIKM_00746 2.7e-70 pdxH S Pfam:Pyridox_oxidase
IEGPKIKM_00747 3.1e-40 rpmA J Ribosomal L27 protein
IEGPKIKM_00748 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
IEGPKIKM_00749 0.0 rne 3.1.26.12 J Ribonuclease E/G family
IEGPKIKM_00750 1.7e-240 dapE 3.5.1.18 E Peptidase dimerisation domain
IEGPKIKM_00751 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
IEGPKIKM_00752 3.3e-256 V Efflux ABC transporter, permease protein
IEGPKIKM_00753 9.2e-164 V ATPases associated with a variety of cellular activities
IEGPKIKM_00754 6.1e-58
IEGPKIKM_00755 1.6e-64
IEGPKIKM_00756 1.8e-278 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
IEGPKIKM_00757 1.6e-188 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IEGPKIKM_00758 5.2e-240 hom 1.1.1.3 E Homoserine dehydrogenase
IEGPKIKM_00759 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
IEGPKIKM_00760 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IEGPKIKM_00761 4.6e-307 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IEGPKIKM_00762 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IEGPKIKM_00763 2.9e-179 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IEGPKIKM_00764 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
IEGPKIKM_00765 1.2e-207 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
IEGPKIKM_00766 4.3e-177 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IEGPKIKM_00768 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
IEGPKIKM_00769 1.8e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
IEGPKIKM_00770 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IEGPKIKM_00771 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
IEGPKIKM_00772 7.1e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
IEGPKIKM_00773 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
IEGPKIKM_00774 3.2e-41 S Protein of unknown function (DUF4244)
IEGPKIKM_00775 3.2e-15 gspF NU Type II secretion system (T2SS), protein F
IEGPKIKM_00776 1.8e-14 gspF NU Type II secretion system (T2SS), protein F
IEGPKIKM_00777 5.7e-121 U Type ii secretion system
IEGPKIKM_00778 3.4e-191 cpaF U Type II IV secretion system protein
IEGPKIKM_00779 2.6e-152 cpaE D bacterial-type flagellum organization
IEGPKIKM_00781 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IEGPKIKM_00782 6.3e-201 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
IEGPKIKM_00783 5e-91
IEGPKIKM_00784 6.6e-49 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IEGPKIKM_00785 2.5e-208 S Glycosyltransferase, group 2 family protein
IEGPKIKM_00786 5.2e-262
IEGPKIKM_00788 8.7e-27 thiS 2.8.1.10 H ThiS family
IEGPKIKM_00789 4.1e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IEGPKIKM_00790 0.0 S Psort location Cytoplasmic, score 8.87
IEGPKIKM_00791 2.4e-28 gtrB GT2 M Glycosyl transferase family 2
IEGPKIKM_00792 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
IEGPKIKM_00793 6.6e-249 V ABC transporter permease
IEGPKIKM_00794 2.4e-184 V ABC transporter
IEGPKIKM_00795 1.9e-138 T HD domain
IEGPKIKM_00796 7.3e-166 S Glutamine amidotransferase domain
IEGPKIKM_00798 0.0 kup P Transport of potassium into the cell
IEGPKIKM_00799 2.2e-184 tatD L TatD related DNase
IEGPKIKM_00800 7.5e-257 xylR 5.3.1.12 G MFS/sugar transport protein
IEGPKIKM_00802 1.7e-82 K Transcriptional regulator
IEGPKIKM_00803 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEGPKIKM_00804 1.6e-130
IEGPKIKM_00805 8.6e-59
IEGPKIKM_00806 5.2e-168 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IEGPKIKM_00807 2.7e-126 dedA S SNARE associated Golgi protein
IEGPKIKM_00809 1.6e-134 S HAD hydrolase, family IA, variant 3
IEGPKIKM_00810 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
IEGPKIKM_00811 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
IEGPKIKM_00812 6.8e-87 hspR K transcriptional regulator, MerR family
IEGPKIKM_00813 2.4e-173 dnaJ1 O DnaJ molecular chaperone homology domain
IEGPKIKM_00814 2.9e-235 G Major Facilitator Superfamily
IEGPKIKM_00815 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
IEGPKIKM_00816 1.3e-224 GK ROK family
IEGPKIKM_00817 2.2e-131 cutC P Participates in the control of copper homeostasis
IEGPKIKM_00818 3.5e-216 GK ROK family
IEGPKIKM_00819 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IEGPKIKM_00820 9.6e-244 nagA 3.5.1.25 G Amidohydrolase family
IEGPKIKM_00821 1.7e-304 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
IEGPKIKM_00822 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
IEGPKIKM_00823 5.1e-191 dppC EP Binding-protein-dependent transport system inner membrane component
IEGPKIKM_00824 0.0 P Belongs to the ABC transporter superfamily
IEGPKIKM_00825 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
IEGPKIKM_00826 5.6e-97 3.6.1.55 F NUDIX domain
IEGPKIKM_00828 4.8e-288 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
IEGPKIKM_00829 0.0 smc D Required for chromosome condensation and partitioning
IEGPKIKM_00830 3.2e-220 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
IEGPKIKM_00832 5.1e-180 S CAAX protease self-immunity
IEGPKIKM_00833 8.9e-220 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
IEGPKIKM_00834 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEGPKIKM_00835 7.4e-226 G Transmembrane secretion effector
IEGPKIKM_00836 8.7e-133 K Bacterial regulatory proteins, tetR family
IEGPKIKM_00837 3e-133
IEGPKIKM_00838 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IEGPKIKM_00839 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IEGPKIKM_00840 2e-167 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
IEGPKIKM_00841 1.2e-186
IEGPKIKM_00842 7.9e-180
IEGPKIKM_00843 1.3e-163 trxA2 O Tetratricopeptide repeat
IEGPKIKM_00844 8.8e-121 cyaA 4.6.1.1 S CYTH
IEGPKIKM_00847 1.4e-184 K Bacterial regulatory proteins, lacI family
IEGPKIKM_00848 1e-16 4.2.1.68 M carboxylic acid catabolic process
IEGPKIKM_00849 6.7e-65 4.2.1.68 M Enolase C-terminal domain-like
IEGPKIKM_00850 2e-163 IQ KR domain
IEGPKIKM_00852 3.9e-172 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
IEGPKIKM_00853 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IEGPKIKM_00854 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEGPKIKM_00855 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
IEGPKIKM_00856 3.7e-201 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IEGPKIKM_00857 8.3e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IEGPKIKM_00858 2.1e-177 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
IEGPKIKM_00859 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
IEGPKIKM_00860 9.8e-107 nusG K Participates in transcription elongation, termination and antitermination
IEGPKIKM_00861 4.7e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IEGPKIKM_00863 6.9e-231 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
IEGPKIKM_00864 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IEGPKIKM_00865 4.1e-298 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IEGPKIKM_00866 3.1e-38 K Psort location Cytoplasmic, score
IEGPKIKM_00867 1.2e-131 K Psort location Cytoplasmic, score
IEGPKIKM_00868 6.1e-32 S Protein of unknown function (DUF3107)
IEGPKIKM_00869 4.6e-245 mphA S Aminoglycoside phosphotransferase
IEGPKIKM_00870 1.3e-282 uvrD2 3.6.4.12 L DNA helicase
IEGPKIKM_00871 1.8e-284 S Zincin-like metallopeptidase
IEGPKIKM_00872 5.5e-150 lon T Belongs to the peptidase S16 family
IEGPKIKM_00873 5.7e-47 S Protein of unknown function (DUF3052)
IEGPKIKM_00874 7.6e-194 K helix_turn _helix lactose operon repressor
IEGPKIKM_00875 2.7e-61 S Thiamine-binding protein
IEGPKIKM_00876 4.6e-163 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IEGPKIKM_00877 6.9e-231 O AAA domain (Cdc48 subfamily)
IEGPKIKM_00878 1.3e-84
IEGPKIKM_00879 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IEGPKIKM_00880 3.4e-158 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IEGPKIKM_00881 4.6e-43 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
IEGPKIKM_00882 1.5e-36 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
IEGPKIKM_00883 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
IEGPKIKM_00884 8.3e-24 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
IEGPKIKM_00885 3.4e-24 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
IEGPKIKM_00886 4.3e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
IEGPKIKM_00887 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
IEGPKIKM_00888 1.3e-199 gluD E Binding-protein-dependent transport system inner membrane component
IEGPKIKM_00889 2.4e-184 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
IEGPKIKM_00890 0.0 L DEAD DEAH box helicase
IEGPKIKM_00891 8.5e-257 rarA L Recombination factor protein RarA
IEGPKIKM_00893 5.7e-256 EGP Major facilitator Superfamily
IEGPKIKM_00894 0.0 ecfA GP ABC transporter, ATP-binding protein
IEGPKIKM_00895 9.6e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IEGPKIKM_00897 1.3e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
IEGPKIKM_00898 2e-213 E Aminotransferase class I and II
IEGPKIKM_00899 4.9e-137 bioM P ATPases associated with a variety of cellular activities
IEGPKIKM_00900 1.3e-69 2.8.2.22 S Arylsulfotransferase Ig-like domain
IEGPKIKM_00901 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IEGPKIKM_00902 1.1e-155 S Tetratricopeptide repeat
IEGPKIKM_00903 7.5e-180 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
IEGPKIKM_00904 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IEGPKIKM_00905 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IEGPKIKM_00906 3e-76
IEGPKIKM_00907 3.1e-58 V MacB-like periplasmic core domain
IEGPKIKM_00908 1.6e-117 K Transcriptional regulatory protein, C terminal
IEGPKIKM_00909 1.3e-239 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IEGPKIKM_00910 4.5e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IEGPKIKM_00911 8.9e-303 ybiT S ABC transporter
IEGPKIKM_00912 8.5e-198 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IEGPKIKM_00913 3.3e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IEGPKIKM_00914 4.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
IEGPKIKM_00915 6.4e-218 GK ROK family
IEGPKIKM_00916 1.5e-177 2.7.1.2 GK ROK family
IEGPKIKM_00917 4.6e-19 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
IEGPKIKM_00918 0.0 tcsS2 T Histidine kinase
IEGPKIKM_00919 3.9e-131 K helix_turn_helix, Lux Regulon
IEGPKIKM_00920 0.0 phoN I PAP2 superfamily
IEGPKIKM_00921 0.0 MV MacB-like periplasmic core domain
IEGPKIKM_00922 8.2e-163 V ABC transporter, ATP-binding protein
IEGPKIKM_00923 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
IEGPKIKM_00924 7.9e-157 S Putative ABC-transporter type IV
IEGPKIKM_00925 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IEGPKIKM_00926 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
IEGPKIKM_00927 3.9e-284 dprA 5.99.1.2 LU DNA recombination-mediator protein A
IEGPKIKM_00928 1e-24 comM O Magnesium chelatase, subunit ChlI C-terminal
IEGPKIKM_00929 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
IEGPKIKM_00930 3e-114
IEGPKIKM_00931 2.5e-94 S Protein of unknown function (DUF4230)
IEGPKIKM_00932 8.5e-119 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
IEGPKIKM_00933 6.2e-29 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEGPKIKM_00934 1.8e-68 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEGPKIKM_00935 1e-31
IEGPKIKM_00936 6.8e-303 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
IEGPKIKM_00937 1.1e-291 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IEGPKIKM_00938 6.8e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IEGPKIKM_00939 7.2e-239 purD 6.3.4.13 F Belongs to the GARS family
IEGPKIKM_00940 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
IEGPKIKM_00941 1.7e-246 S Putative esterase
IEGPKIKM_00942 0.0 lysX S Uncharacterised conserved protein (DUF2156)
IEGPKIKM_00944 1.5e-22 P Zinc-uptake complex component A periplasmic
IEGPKIKM_00946 8.8e-91
IEGPKIKM_00947 1.2e-64 D MobA/MobL family
IEGPKIKM_00948 2.8e-46 L Transposase
IEGPKIKM_00949 2.8e-179 tnp7109-21 L Integrase core domain
IEGPKIKM_00950 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
IEGPKIKM_00951 9e-40
IEGPKIKM_00952 3.6e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
IEGPKIKM_00954 8.1e-47 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IEGPKIKM_00956 6.3e-241 pbuX F Permease family
IEGPKIKM_00957 1.9e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IEGPKIKM_00958 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
IEGPKIKM_00959 0.0 pcrA 3.6.4.12 L DNA helicase
IEGPKIKM_00960 4.8e-64 S Domain of unknown function (DUF4418)
IEGPKIKM_00961 8.5e-213 V FtsX-like permease family
IEGPKIKM_00962 1.9e-128 lolD V ABC transporter
IEGPKIKM_00963 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IEGPKIKM_00964 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
IEGPKIKM_00965 3.4e-123 S HAD hydrolase, family IA, variant 3
IEGPKIKM_00966 8.6e-201 P NMT1/THI5 like
IEGPKIKM_00967 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
IEGPKIKM_00968 1.2e-140
IEGPKIKM_00969 1.1e-126 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
IEGPKIKM_00970 1.8e-262 EGP Major facilitator Superfamily
IEGPKIKM_00971 6.8e-98 S GtrA-like protein
IEGPKIKM_00972 1.3e-62 S Macrophage migration inhibitory factor (MIF)
IEGPKIKM_00973 3.8e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
IEGPKIKM_00974 0.0 pepD E Peptidase family C69
IEGPKIKM_00975 1.3e-107 S Phosphatidylethanolamine-binding protein
IEGPKIKM_00976 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
IEGPKIKM_00979 2.6e-68 S Domain of unknown function (DUF4190)
IEGPKIKM_00980 6.9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IEGPKIKM_00981 3e-153 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IEGPKIKM_00983 3.6e-22 S Helix-turn-helix domain
IEGPKIKM_00984 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
IEGPKIKM_00985 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
IEGPKIKM_00986 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
IEGPKIKM_00987 8.9e-184 lacR K Transcriptional regulator, LacI family
IEGPKIKM_00988 5.2e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IEGPKIKM_00989 3.9e-119 K Transcriptional regulatory protein, C terminal
IEGPKIKM_00990 2.2e-95
IEGPKIKM_00991 9.7e-178 V N-Acetylmuramoyl-L-alanine amidase
IEGPKIKM_00992 7.4e-109 ytrE V ABC transporter
IEGPKIKM_00993 6.6e-172
IEGPKIKM_00994 1.7e-11 S Psort location CytoplasmicMembrane, score 9.99
IEGPKIKM_00995 2.3e-219 vex3 V ABC transporter permease
IEGPKIKM_00996 3.6e-211 vex1 V Efflux ABC transporter, permease protein
IEGPKIKM_00997 9.9e-112 vex2 V ABC transporter, ATP-binding protein
IEGPKIKM_00998 2.2e-38 azlD E Branched-chain amino acid transport protein (AzlD)
IEGPKIKM_00999 4.8e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
IEGPKIKM_01000 1.8e-95 ptpA 3.1.3.48 T low molecular weight
IEGPKIKM_01001 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
IEGPKIKM_01002 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IEGPKIKM_01003 3.8e-72 attW O OsmC-like protein
IEGPKIKM_01004 1.6e-191 T Universal stress protein family
IEGPKIKM_01005 2.4e-107 M NlpC/P60 family
IEGPKIKM_01006 3.1e-176 usp 3.5.1.28 CBM50 S CHAP domain
IEGPKIKM_01007 8.5e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IEGPKIKM_01008 2.6e-39
IEGPKIKM_01009 6.6e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
IEGPKIKM_01010 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
IEGPKIKM_01011 4.2e-07 EGP Major facilitator Superfamily
IEGPKIKM_01012 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IEGPKIKM_01013 4.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
IEGPKIKM_01014 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IEGPKIKM_01016 2.8e-216 araJ EGP Major facilitator Superfamily
IEGPKIKM_01017 0.0 S Domain of unknown function (DUF4037)
IEGPKIKM_01018 1.5e-112 S Protein of unknown function (DUF4125)
IEGPKIKM_01019 2.9e-131
IEGPKIKM_01020 3.6e-289 pspC KT PspC domain
IEGPKIKM_01021 2.7e-266 tcsS3 KT PspC domain
IEGPKIKM_01022 9.2e-126 degU K helix_turn_helix, Lux Regulon
IEGPKIKM_01023 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IEGPKIKM_01025 2.3e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
IEGPKIKM_01026 4.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
IEGPKIKM_01027 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IEGPKIKM_01028 5.3e-95
IEGPKIKM_01030 3.6e-290 sufB O FeS assembly protein SufB
IEGPKIKM_01031 2.6e-233 sufD O FeS assembly protein SufD
IEGPKIKM_01032 1.4e-144 sufC O FeS assembly ATPase SufC
IEGPKIKM_01033 3.5e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IEGPKIKM_01034 8.8e-101 iscU C SUF system FeS assembly protein, NifU family
IEGPKIKM_01035 5.2e-92 yitW S Iron-sulfur cluster assembly protein
IEGPKIKM_01036 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IEGPKIKM_01037 7.6e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
IEGPKIKM_01039 1.4e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IEGPKIKM_01040 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
IEGPKIKM_01041 2e-197 phoH T PhoH-like protein
IEGPKIKM_01042 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IEGPKIKM_01043 2.4e-251 corC S CBS domain
IEGPKIKM_01044 5.1e-187 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IEGPKIKM_01045 0.0 fadD 6.2.1.3 I AMP-binding enzyme
IEGPKIKM_01046 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
IEGPKIKM_01047 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
IEGPKIKM_01048 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
IEGPKIKM_01049 1.4e-172 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IEGPKIKM_01050 0.0 gcs2 S A circularly permuted ATPgrasp
IEGPKIKM_01051 1.3e-153 E Transglutaminase/protease-like homologues
IEGPKIKM_01053 3.4e-131 L Transposase and inactivated derivatives
IEGPKIKM_01054 7.9e-161
IEGPKIKM_01055 2.8e-188 nusA K Participates in both transcription termination and antitermination
IEGPKIKM_01056 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IEGPKIKM_01057 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IEGPKIKM_01058 2.1e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IEGPKIKM_01060 6.5e-219 steT E amino acid
IEGPKIKM_01061 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
IEGPKIKM_01062 1.4e-29 rpmB J Ribosomal L28 family
IEGPKIKM_01063 3.2e-200 yegV G pfkB family carbohydrate kinase
IEGPKIKM_01065 5e-243 yxiO S Vacuole effluxer Atg22 like
IEGPKIKM_01066 1.7e-131 K helix_turn_helix, mercury resistance
IEGPKIKM_01067 2.6e-17 T Toxic component of a toxin-antitoxin (TA) module
IEGPKIKM_01068 3.7e-54 relB L RelB antitoxin
IEGPKIKM_01069 3e-74
IEGPKIKM_01070 5.6e-119 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
IEGPKIKM_01071 2.5e-20 relB L RelB antitoxin
IEGPKIKM_01072 1e-162 L Transposase
IEGPKIKM_01073 3.2e-33 3.4.11.5 I carboxylic ester hydrolase activity
IEGPKIKM_01074 3e-237 K Helix-turn-helix XRE-family like proteins
IEGPKIKM_01075 2.6e-129 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
IEGPKIKM_01080 4.2e-11
IEGPKIKM_01081 3.5e-07 S Scramblase
IEGPKIKM_01082 5.5e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IEGPKIKM_01083 7e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
IEGPKIKM_01084 2.9e-179 xerD D recombinase XerD
IEGPKIKM_01085 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IEGPKIKM_01086 2.1e-25 rpmI J Ribosomal protein L35
IEGPKIKM_01087 2.1e-110 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IEGPKIKM_01089 8e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
IEGPKIKM_01090 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IEGPKIKM_01091 2.4e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IEGPKIKM_01093 2e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IEGPKIKM_01094 9.1e-194 galM 5.1.3.3 G Aldose 1-epimerase
IEGPKIKM_01095 2e-64
IEGPKIKM_01096 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
IEGPKIKM_01097 4.8e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IEGPKIKM_01098 1.3e-190 V Acetyltransferase (GNAT) domain
IEGPKIKM_01099 7.6e-230 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
IEGPKIKM_01100 5.5e-244 yxbA 6.3.1.12 S ATP-grasp
IEGPKIKM_01101 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
IEGPKIKM_01102 2e-25 ywiC S YwiC-like protein
IEGPKIKM_01103 4.2e-08 ywiC S YwiC-like protein
IEGPKIKM_01104 8.7e-167 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
IEGPKIKM_01105 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IEGPKIKM_01106 3.7e-232 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
IEGPKIKM_01107 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
IEGPKIKM_01108 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
IEGPKIKM_01109 1e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IEGPKIKM_01110 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
IEGPKIKM_01111 1.2e-118
IEGPKIKM_01112 2.6e-112 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
IEGPKIKM_01113 1.3e-246 M Bacterial capsule synthesis protein PGA_cap
IEGPKIKM_01115 1.3e-38 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEGPKIKM_01116 2.3e-41 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEGPKIKM_01117 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
IEGPKIKM_01118 4.9e-171 L Transposase and inactivated derivatives IS30 family
IEGPKIKM_01119 0.0 yegQ O Peptidase family U32 C-terminal domain
IEGPKIKM_01120 3.3e-186 yfiH Q Multi-copper polyphenol oxidoreductase laccase
IEGPKIKM_01121 6.5e-145 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IEGPKIKM_01122 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IEGPKIKM_01123 3.1e-52 D nuclear chromosome segregation
IEGPKIKM_01124 3.2e-269 pepC 3.4.22.40 E Peptidase C1-like family
IEGPKIKM_01125 2.8e-164 L Excalibur calcium-binding domain
IEGPKIKM_01126 1.3e-218 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IEGPKIKM_01127 4e-243 EGP Major facilitator Superfamily
IEGPKIKM_01128 1e-105 K helix_turn_helix, Arsenical Resistance Operon Repressor
IEGPKIKM_01129 5.5e-65 rplQ J Ribosomal protein L17
IEGPKIKM_01130 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEGPKIKM_01131 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IEGPKIKM_01132 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IEGPKIKM_01133 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IEGPKIKM_01134 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IEGPKIKM_01135 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IEGPKIKM_01136 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IEGPKIKM_01137 2.7e-63 rplO J binds to the 23S rRNA
IEGPKIKM_01138 1e-24 rpmD J Ribosomal protein L30p/L7e
IEGPKIKM_01139 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IEGPKIKM_01140 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IEGPKIKM_01141 4e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IEGPKIKM_01142 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IEGPKIKM_01143 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IEGPKIKM_01144 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IEGPKIKM_01145 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IEGPKIKM_01146 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IEGPKIKM_01147 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IEGPKIKM_01148 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
IEGPKIKM_01149 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IEGPKIKM_01150 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IEGPKIKM_01151 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IEGPKIKM_01152 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IEGPKIKM_01153 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IEGPKIKM_01154 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IEGPKIKM_01155 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
IEGPKIKM_01156 1.2e-117 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IEGPKIKM_01157 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
IEGPKIKM_01158 9.9e-13 3.2.1.14 GH18 EM Domain of unknown function (DUF5011)
IEGPKIKM_01159 3.2e-201 K helix_turn _helix lactose operon repressor
IEGPKIKM_01160 2.5e-103 G Glycosyl hydrolases family 43
IEGPKIKM_01161 2.2e-174 G Glycosyl hydrolases family 43
IEGPKIKM_01164 3.7e-111 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IEGPKIKM_01165 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IEGPKIKM_01166 0.0 fadD 6.2.1.3 I AMP-binding enzyme
IEGPKIKM_01167 4.4e-208 K helix_turn _helix lactose operon repressor
IEGPKIKM_01168 2.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEGPKIKM_01169 4.4e-157 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IEGPKIKM_01170 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IEGPKIKM_01171 1.1e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
IEGPKIKM_01172 3.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
IEGPKIKM_01173 4.7e-31 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
IEGPKIKM_01174 1.7e-191 V N-Acetylmuramoyl-L-alanine amidase
IEGPKIKM_01175 4e-259 argE E Peptidase dimerisation domain
IEGPKIKM_01176 4.2e-104 S Protein of unknown function (DUF3043)
IEGPKIKM_01177 8.9e-281 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEGPKIKM_01178 9.4e-144 S Domain of unknown function (DUF4191)
IEGPKIKM_01179 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
IEGPKIKM_01180 2.6e-160 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
IEGPKIKM_01181 5.7e-211 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IEGPKIKM_01182 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IEGPKIKM_01183 3e-173 S Tetratricopeptide repeat
IEGPKIKM_01184 2.1e-25 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
IEGPKIKM_01185 3e-31 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
IEGPKIKM_01186 1.3e-11 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
IEGPKIKM_01187 2.8e-293 plyA3 M Parallel beta-helix repeats
IEGPKIKM_01188 5.2e-19 plyA3 M Parallel beta-helix repeats
IEGPKIKM_01189 1.9e-255 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
IEGPKIKM_01190 5.1e-162
IEGPKIKM_01191 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
IEGPKIKM_01193 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IEGPKIKM_01194 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
IEGPKIKM_01195 2e-46 yhbY J CRS1_YhbY
IEGPKIKM_01196 0.0 4.2.1.53 S MCRA family
IEGPKIKM_01199 1.2e-202 K WYL domain
IEGPKIKM_01200 1.3e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
IEGPKIKM_01201 5.4e-172 dkgA 1.1.1.346 C Aldo/keto reductase family
IEGPKIKM_01202 1.3e-75 yneG S Domain of unknown function (DUF4186)
IEGPKIKM_01204 7.8e-08 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
IEGPKIKM_01205 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
IEGPKIKM_01206 5.5e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IEGPKIKM_01207 4.2e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IEGPKIKM_01208 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
IEGPKIKM_01209 5.9e-113
IEGPKIKM_01210 1.1e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IEGPKIKM_01211 1.2e-129 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
IEGPKIKM_01212 1.6e-282 S Uncharacterized protein conserved in bacteria (DUF2252)
IEGPKIKM_01213 1.1e-264 glnA2 6.3.1.2 E glutamine synthetase
IEGPKIKM_01214 1.8e-251 S Domain of unknown function (DUF5067)
IEGPKIKM_01215 2.3e-60 EGP Major facilitator Superfamily
IEGPKIKM_01216 1.1e-176 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
IEGPKIKM_01217 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
IEGPKIKM_01218 1.4e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
IEGPKIKM_01219 2.3e-170
IEGPKIKM_01220 4.5e-272 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IEGPKIKM_01221 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
IEGPKIKM_01222 1.2e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEGPKIKM_01223 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IEGPKIKM_01224 1.6e-45 M Lysin motif
IEGPKIKM_01225 8.8e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IEGPKIKM_01226 6.4e-229 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IEGPKIKM_01227 0.0 L DNA helicase
IEGPKIKM_01228 1.3e-90 mraZ K Belongs to the MraZ family
IEGPKIKM_01229 1.2e-186 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IEGPKIKM_01230 2.5e-59 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IEGPKIKM_01231 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
IEGPKIKM_01232 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IEGPKIKM_01233 2e-283 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IEGPKIKM_01234 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IEGPKIKM_01235 1.2e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IEGPKIKM_01236 9e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
IEGPKIKM_01237 5.5e-217 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IEGPKIKM_01238 6.1e-296 murC 6.3.2.8 M Belongs to the MurCDEF family
IEGPKIKM_01239 5e-160 ftsQ 6.3.2.4 D Cell division protein FtsQ
IEGPKIKM_01240 1.3e-37
IEGPKIKM_01242 1e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IEGPKIKM_01243 1.7e-85 brnQ U Component of the transport system for branched-chain amino acids
IEGPKIKM_01244 1.2e-143 yoaK S Protein of unknown function (DUF1275)
IEGPKIKM_01245 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IEGPKIKM_01246 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
IEGPKIKM_01247 2.5e-207 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IEGPKIKM_01248 1.4e-209 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IEGPKIKM_01249 1.7e-158 G Fructosamine kinase
IEGPKIKM_01250 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IEGPKIKM_01251 2.8e-156 S PAC2 family
IEGPKIKM_01255 1.3e-261
IEGPKIKM_01258 1.5e-20 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IEGPKIKM_01259 2.1e-118 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IEGPKIKM_01260 3.1e-45 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IEGPKIKM_01261 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IEGPKIKM_01262 5.7e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IEGPKIKM_01264 7.6e-92 ilvN 2.2.1.6 E ACT domain
IEGPKIKM_01265 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
IEGPKIKM_01266 1e-139 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IEGPKIKM_01267 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IEGPKIKM_01268 1e-113 yceD S Uncharacterized ACR, COG1399
IEGPKIKM_01269 5.2e-106
IEGPKIKM_01270 3.1e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IEGPKIKM_01271 2e-58 S Protein of unknown function (DUF3039)
IEGPKIKM_01272 0.0 yjjK S ABC transporter
IEGPKIKM_01273 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
IEGPKIKM_01274 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
IEGPKIKM_01276 7.2e-75
IEGPKIKM_01277 3.1e-147 S von Willebrand factor (vWF) type A domain
IEGPKIKM_01278 2.3e-190 S von Willebrand factor (vWF) type A domain
IEGPKIKM_01279 6.4e-94
IEGPKIKM_01280 1.5e-175 S Protein of unknown function DUF58
IEGPKIKM_01281 5e-196 moxR S ATPase family associated with various cellular activities (AAA)
IEGPKIKM_01282 3.1e-144 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IEGPKIKM_01283 3.4e-71 S LytR cell envelope-related transcriptional attenuator
IEGPKIKM_01284 1.4e-43 cspA K 'Cold-shock' DNA-binding domain
IEGPKIKM_01285 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IEGPKIKM_01286 1.7e-10 S Proteins of 100 residues with WXG
IEGPKIKM_01287 1.4e-161
IEGPKIKM_01288 2.1e-134 KT Response regulator receiver domain protein
IEGPKIKM_01289 2.4e-75 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
IEGPKIKM_01290 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IEGPKIKM_01291 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IEGPKIKM_01292 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IEGPKIKM_01293 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IEGPKIKM_01294 1.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IEGPKIKM_01295 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IEGPKIKM_01296 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IEGPKIKM_01298 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
IEGPKIKM_01299 4.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IEGPKIKM_01301 2.4e-91 L Phage integrase family
IEGPKIKM_01303 1.2e-38
IEGPKIKM_01304 2.4e-12 S Putative phage holin Dp-1
IEGPKIKM_01305 2e-125 3.5.1.28 M NLP P60 protein
IEGPKIKM_01306 7.9e-65 S SPP1 phage holin
IEGPKIKM_01308 1.4e-69
IEGPKIKM_01309 1.6e-35
IEGPKIKM_01310 4.6e-310 E ABC transporter, substrate-binding protein, family 5
IEGPKIKM_01311 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IEGPKIKM_01312 2e-277 G Bacterial extracellular solute-binding protein
IEGPKIKM_01313 1.2e-62 G carbohydrate transport
IEGPKIKM_01314 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
IEGPKIKM_01315 5.5e-124 G ABC transporter permease
IEGPKIKM_01316 2.9e-190 K Periplasmic binding protein domain
IEGPKIKM_01317 7.7e-21 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IEGPKIKM_01318 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
IEGPKIKM_01319 1.3e-284 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
IEGPKIKM_01320 1.3e-249 V ABC-2 family transporter protein
IEGPKIKM_01321 8.1e-227 V ABC-2 family transporter protein
IEGPKIKM_01322 1.3e-182 V ATPases associated with a variety of cellular activities
IEGPKIKM_01323 1.2e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
IEGPKIKM_01324 3.2e-234 T Histidine kinase
IEGPKIKM_01325 1.7e-120 K helix_turn_helix, Lux Regulon
IEGPKIKM_01326 1.1e-115 MA20_27875 P Protein of unknown function DUF47
IEGPKIKM_01327 1.5e-189 pit P Phosphate transporter family
IEGPKIKM_01328 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
IEGPKIKM_01329 2.1e-108 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IEGPKIKM_01330 1.9e-162 sprF 4.6.1.1 M Cell surface antigen C-terminus
IEGPKIKM_01331 8.9e-26
IEGPKIKM_01332 3.3e-139
IEGPKIKM_01333 1e-62 S PrgI family protein
IEGPKIKM_01334 0.0 trsE U type IV secretory pathway VirB4
IEGPKIKM_01335 1.4e-205 isp2 3.2.1.96 M CHAP domain
IEGPKIKM_01336 3.6e-14 U Type IV secretory system Conjugative DNA transfer
IEGPKIKM_01337 1.1e-126
IEGPKIKM_01339 1.1e-100 K Helix-turn-helix domain protein
IEGPKIKM_01342 2e-58 U Type IV secretory system Conjugative DNA transfer
IEGPKIKM_01343 9.8e-241 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IEGPKIKM_01345 6.5e-273 recD2 3.6.4.12 L PIF1-like helicase
IEGPKIKM_01346 1.1e-161 supH S Sucrose-6F-phosphate phosphohydrolase
IEGPKIKM_01347 6.3e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
IEGPKIKM_01348 3.6e-123 KT Transcriptional regulatory protein, C terminal
IEGPKIKM_01349 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
IEGPKIKM_01350 2.7e-267 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IEGPKIKM_01351 6.2e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
IEGPKIKM_01352 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
IEGPKIKM_01353 1.7e-120 rsmD 2.1.1.171 L Conserved hypothetical protein 95
IEGPKIKM_01354 1.7e-105 XK27_02070 S Nitroreductase family
IEGPKIKM_01355 3.8e-81 hsp20 O Hsp20/alpha crystallin family
IEGPKIKM_01356 4.3e-162 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IEGPKIKM_01357 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IEGPKIKM_01358 1.8e-34 CP_0960 S Belongs to the UPF0109 family
IEGPKIKM_01359 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IEGPKIKM_01360 1.5e-294 ydfD EK Alanine-glyoxylate amino-transferase
IEGPKIKM_01361 1.3e-93 argO S LysE type translocator
IEGPKIKM_01362 2.8e-221 S Endonuclease/Exonuclease/phosphatase family
IEGPKIKM_01363 1.9e-271 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IEGPKIKM_01364 1.4e-164 P Cation efflux family
IEGPKIKM_01365 1.2e-41
IEGPKIKM_01366 1.2e-183 xerC D Belongs to the 'phage' integrase family. XerC subfamily
IEGPKIKM_01367 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
IEGPKIKM_01368 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
IEGPKIKM_01369 0.0 oppD P Belongs to the ABC transporter superfamily
IEGPKIKM_01370 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
IEGPKIKM_01371 3.1e-275 pepC 3.4.22.40 E Peptidase C1-like family
IEGPKIKM_01372 4.8e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
IEGPKIKM_01373 2.1e-138 S Protein of unknown function (DUF3710)
IEGPKIKM_01374 6.1e-124 S Protein of unknown function (DUF3159)
IEGPKIKM_01375 3.1e-29 L Transposase
IEGPKIKM_01376 4.4e-45 L Transposase DDE domain
IEGPKIKM_01377 1.6e-290 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IEGPKIKM_01378 0.0 3.6.4.12 K Putative DNA-binding domain
IEGPKIKM_01379 2.5e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IEGPKIKM_01380 0.0
IEGPKIKM_01381 1.8e-173 rfbJ M Glycosyl transferase family 2
IEGPKIKM_01382 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
IEGPKIKM_01383 1.1e-24 I transferase activity, transferring acyl groups other than amino-acyl groups
IEGPKIKM_01384 1e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IEGPKIKM_01385 2.7e-111 T protein histidine kinase activity
IEGPKIKM_01386 2.4e-53 K LytTr DNA-binding domain
IEGPKIKM_01387 1.1e-25 K LytTr DNA-binding domain
IEGPKIKM_01388 1e-47 S Protein of unknown function (DUF3073)
IEGPKIKM_01389 3.2e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IEGPKIKM_01390 1.5e-194 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
IEGPKIKM_01391 5.2e-17 S Amidohydrolase family
IEGPKIKM_01392 7e-155 S Amidohydrolase family
IEGPKIKM_01393 0.0 yjjP S Threonine/Serine exporter, ThrE
IEGPKIKM_01394 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IEGPKIKM_01395 1.2e-236 yhjX EGP Major facilitator Superfamily
IEGPKIKM_01396 6.5e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
IEGPKIKM_01397 0.0 trxB1 1.8.1.9 C Thioredoxin domain
IEGPKIKM_01398 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
IEGPKIKM_01399 6.9e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
IEGPKIKM_01400 1.1e-95 K helix_turn _helix lactose operon repressor
IEGPKIKM_01401 1.2e-241 ytfL P Transporter associated domain
IEGPKIKM_01402 1.3e-188 yddG EG EamA-like transporter family
IEGPKIKM_01403 1.9e-83 dps P Belongs to the Dps family
IEGPKIKM_01404 1.2e-137 S Protein of unknown function DUF45
IEGPKIKM_01405 1.6e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
IEGPKIKM_01406 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
IEGPKIKM_01407 8.6e-78 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IEGPKIKM_01408 1.3e-188 K helix_turn _helix lactose operon repressor
IEGPKIKM_01409 0.0 G Glycosyl hydrolase family 20, domain 2
IEGPKIKM_01412 0.0 3.2.1.55 GH51 G arabinose metabolic process
IEGPKIKM_01413 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IEGPKIKM_01414 2.5e-124 gntR K FCD
IEGPKIKM_01415 5.4e-113 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IEGPKIKM_01416 1.1e-149 nrtR 3.6.1.55 F NUDIX hydrolase
IEGPKIKM_01417 9.8e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IEGPKIKM_01418 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
IEGPKIKM_01419 1.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
IEGPKIKM_01420 3.4e-236 iscS1 2.8.1.7 E Aminotransferase class-V
IEGPKIKM_01421 0.0 typA T Elongation factor G C-terminus
IEGPKIKM_01422 7.8e-78
IEGPKIKM_01423 1.7e-198 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
IEGPKIKM_01424 1.9e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
IEGPKIKM_01425 3.5e-100 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
IEGPKIKM_01426 2.3e-150 L HNH endonuclease
IEGPKIKM_01427 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
IEGPKIKM_01428 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IEGPKIKM_01429 3.9e-129 L Transposase
IEGPKIKM_01430 2.1e-41 XAC3035 O Glutaredoxin
IEGPKIKM_01431 2.1e-150 S Virulence factor BrkB
IEGPKIKM_01432 7.6e-100 bcp 1.11.1.15 O Redoxin
IEGPKIKM_01433 1.2e-39 E ABC transporter
IEGPKIKM_01435 9.8e-277 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IEGPKIKM_01436 2.6e-97 S Domain of unknown function (DUF4143)
IEGPKIKM_01437 3.6e-45 S Domain of unknown function (DUF4143)
IEGPKIKM_01440 3.7e-251 S Calcineurin-like phosphoesterase
IEGPKIKM_01441 8.2e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
IEGPKIKM_01442 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IEGPKIKM_01443 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IEGPKIKM_01444 1.2e-177 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
IEGPKIKM_01445 1.2e-48 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IEGPKIKM_01446 2.1e-249 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEGPKIKM_01447 4.6e-67 S haloacid dehalogenase-like hydrolase
IEGPKIKM_01448 3.6e-131 yydK K UTRA
IEGPKIKM_01449 1.3e-70 S FMN_bind
IEGPKIKM_01450 1.8e-147 macB V ABC transporter, ATP-binding protein
IEGPKIKM_01451 4.8e-206 Z012_06715 V FtsX-like permease family
IEGPKIKM_01452 9.7e-223 macB_2 V ABC transporter permease
IEGPKIKM_01453 9.2e-234 S Predicted membrane protein (DUF2318)
IEGPKIKM_01454 1.8e-106 tpd P Fe2+ transport protein
IEGPKIKM_01455 7.3e-306 efeU_1 P Iron permease FTR1 family
IEGPKIKM_01456 4.7e-141 3.5.2.6 V Beta-lactamase enzyme family
IEGPKIKM_01457 1.6e-168 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
IEGPKIKM_01458 3.2e-103
IEGPKIKM_01459 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
IEGPKIKM_01460 1.2e-178 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
IEGPKIKM_01461 2.6e-163 glcU G Sugar transport protein
IEGPKIKM_01462 7.6e-194 K helix_turn_helix, arabinose operon control protein
IEGPKIKM_01464 3.9e-36 rpmE J Binds the 23S rRNA
IEGPKIKM_01465 1.2e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IEGPKIKM_01466 3.1e-189 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IEGPKIKM_01467 5.5e-178 3.4.22.70 M Sortase family
IEGPKIKM_01468 0.0 M chlorophyll binding
IEGPKIKM_01469 6.4e-304 M LPXTG cell wall anchor motif
IEGPKIKM_01470 2.7e-82 K Winged helix DNA-binding domain
IEGPKIKM_01471 1.8e-301 V ABC transporter, ATP-binding protein
IEGPKIKM_01472 0.0 V ABC transporter transmembrane region
IEGPKIKM_01473 1.7e-81
IEGPKIKM_01474 1.3e-69 XK26_04485 P Cobalt transport protein
IEGPKIKM_01475 2.9e-19 XK26_04485 P Cobalt transport protein
IEGPKIKM_01477 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
IEGPKIKM_01478 0.0 S Glycosyl transferase, family 2
IEGPKIKM_01479 7.5e-259
IEGPKIKM_01480 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
IEGPKIKM_01481 3.4e-157 cof 5.2.1.8 T Eukaryotic phosphomannomutase
IEGPKIKM_01482 1.4e-130 ctsW S Phosphoribosyl transferase domain
IEGPKIKM_01483 3.6e-72 rulA 3.4.21.88 KT Peptidase S24-like
IEGPKIKM_01484 4.3e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
IEGPKIKM_01485 1.9e-127 T Response regulator receiver domain protein
IEGPKIKM_01486 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IEGPKIKM_01487 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IEGPKIKM_01488 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
IEGPKIKM_01489 1e-131 yebC K transcriptional regulatory protein
IEGPKIKM_01490 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IEGPKIKM_01491 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IEGPKIKM_01492 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IEGPKIKM_01493 2.6e-44 yajC U Preprotein translocase subunit
IEGPKIKM_01494 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IEGPKIKM_01495 4.3e-71 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IEGPKIKM_01496 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IEGPKIKM_01497 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
IEGPKIKM_01498 5.9e-227 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IEGPKIKM_01499 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IEGPKIKM_01500 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IEGPKIKM_01501 7.1e-308 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IEGPKIKM_01502 8.2e-246 G Bacterial extracellular solute-binding protein
IEGPKIKM_01503 1.1e-173 G Binding-protein-dependent transport system inner membrane component
IEGPKIKM_01504 6.5e-168 G ABC transporter permease
IEGPKIKM_01505 6.4e-221 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
IEGPKIKM_01506 8.8e-213 gatC G PTS system sugar-specific permease component
IEGPKIKM_01507 1.4e-173 K Putative sugar-binding domain
IEGPKIKM_01509 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
IEGPKIKM_01510 3.5e-277 abcT3 P ATPases associated with a variety of cellular activities
IEGPKIKM_01511 6.9e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
IEGPKIKM_01512 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
IEGPKIKM_01513 5.9e-85 yjcF Q Acetyltransferase (GNAT) domain
IEGPKIKM_01514 7.6e-157 I Serine aminopeptidase, S33
IEGPKIKM_01515 9.3e-53 ybjQ S Putative heavy-metal-binding
IEGPKIKM_01516 5.7e-36 D DivIVA domain protein
IEGPKIKM_01517 2.5e-89 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
IEGPKIKM_01518 0.0 KL Domain of unknown function (DUF3427)
IEGPKIKM_01520 3.5e-196 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IEGPKIKM_01522 7.6e-103
IEGPKIKM_01523 7.4e-167 yicL EG EamA-like transporter family
IEGPKIKM_01524 1.5e-205 pldB 3.1.1.5 I Serine aminopeptidase, S33
IEGPKIKM_01525 3e-146 pip S YhgE Pip domain protein
IEGPKIKM_01526 0.0 pip S YhgE Pip domain protein
IEGPKIKM_01527 0.0 pip S YhgE Pip domain protein
IEGPKIKM_01528 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
IEGPKIKM_01529 1e-130 fhaA T Protein of unknown function (DUF2662)
IEGPKIKM_01530 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
IEGPKIKM_01531 1.4e-258 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
IEGPKIKM_01532 2.8e-266 rodA D Belongs to the SEDS family
IEGPKIKM_01533 1.7e-263 pbpA M penicillin-binding protein
IEGPKIKM_01534 2e-183 T Protein tyrosine kinase
IEGPKIKM_01535 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
IEGPKIKM_01536 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
IEGPKIKM_01537 1.7e-232 srtA 3.4.22.70 M Sortase family
IEGPKIKM_01538 7.9e-143 S Bacterial protein of unknown function (DUF881)
IEGPKIKM_01539 2.6e-71 crgA D Involved in cell division
IEGPKIKM_01540 2.8e-257 L ribosomal rna small subunit methyltransferase
IEGPKIKM_01541 1.3e-120 L HTH-like domain
IEGPKIKM_01542 1.9e-144 gluP 3.4.21.105 S Rhomboid family
IEGPKIKM_01543 3.4e-35
IEGPKIKM_01544 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IEGPKIKM_01545 2e-73 I Sterol carrier protein
IEGPKIKM_01546 2.6e-38 V ATPases associated with a variety of cellular activities
IEGPKIKM_01547 6.2e-44 L Transposase
IEGPKIKM_01548 2.7e-26 L IstB-like ATP binding protein
IEGPKIKM_01549 8.1e-41 tnp7109-21 L Integrase core domain
IEGPKIKM_01550 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
IEGPKIKM_01551 3.5e-12
IEGPKIKM_01552 1.9e-15 yccF S Inner membrane component domain
IEGPKIKM_01553 7e-256 S Domain of unknown function (DUF4143)
IEGPKIKM_01554 1.5e-112 K WHG domain
IEGPKIKM_01555 1.4e-90 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
IEGPKIKM_01557 7.9e-17 M Belongs to the glycosyl hydrolase 30 family
IEGPKIKM_01558 2.6e-99 M Belongs to the glycosyl hydrolase 30 family
IEGPKIKM_01560 3.3e-191 1.1.1.65 C Aldo/keto reductase family
IEGPKIKM_01561 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
IEGPKIKM_01562 0.0 lmrA1 V ABC transporter, ATP-binding protein
IEGPKIKM_01563 0.0 lmrA2 V ABC transporter transmembrane region
IEGPKIKM_01564 2.4e-256 L Phage integrase family
IEGPKIKM_01565 1.1e-49 relB L RelB antitoxin
IEGPKIKM_01566 1.8e-68 T Toxic component of a toxin-antitoxin (TA) module
IEGPKIKM_01567 1.3e-207 E Belongs to the peptidase S1B family
IEGPKIKM_01568 6.9e-12
IEGPKIKM_01569 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IEGPKIKM_01570 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IEGPKIKM_01571 1.4e-47 S Domain of unknown function (DUF4193)
IEGPKIKM_01572 1.2e-173 S Protein of unknown function (DUF3071)
IEGPKIKM_01573 3.3e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
IEGPKIKM_01574 7.6e-115 S Vitamin K epoxide reductase
IEGPKIKM_01575 1.5e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
IEGPKIKM_01576 1.1e-152 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IEGPKIKM_01577 3.6e-169 S Patatin-like phospholipase
IEGPKIKM_01578 0.0 V ABC transporter transmembrane region
IEGPKIKM_01579 0.0 V ABC transporter, ATP-binding protein
IEGPKIKM_01580 1.1e-90 K MarR family
IEGPKIKM_01581 7.9e-69 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
IEGPKIKM_01582 1.2e-269 yhdG E aromatic amino acid transport protein AroP K03293
IEGPKIKM_01583 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IEGPKIKM_01584 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IEGPKIKM_01585 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IEGPKIKM_01586 1.1e-217 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
IEGPKIKM_01587 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
IEGPKIKM_01588 4.4e-109
IEGPKIKM_01589 4.8e-117 parA D AAA domain
IEGPKIKM_01590 4e-92 S Transcription factor WhiB
IEGPKIKM_01591 1.1e-42
IEGPKIKM_01592 3e-183 S Helix-turn-helix domain
IEGPKIKM_01593 1.3e-17
IEGPKIKM_01594 5.9e-28
IEGPKIKM_01595 5.5e-118
IEGPKIKM_01596 4.3e-132
IEGPKIKM_01597 6.3e-50
IEGPKIKM_01598 1.1e-176 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IEGPKIKM_01599 7.1e-166 S Sucrose-6F-phosphate phosphohydrolase
IEGPKIKM_01600 1.1e-87 P ABC-type metal ion transport system permease component
IEGPKIKM_01601 1.3e-19 S Peptidase dimerisation domain
IEGPKIKM_01602 2.8e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IEGPKIKM_01603 6e-249 rnd 3.1.13.5 J 3'-5' exonuclease
IEGPKIKM_01604 4.4e-114 S Protein of unknown function (DUF3000)
IEGPKIKM_01605 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IEGPKIKM_01606 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
IEGPKIKM_01607 1.2e-38
IEGPKIKM_01608 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IEGPKIKM_01609 2.8e-96 S Peptidase dimerisation domain
IEGPKIKM_01610 1.4e-58 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IEGPKIKM_01611 0.0 dnaK O Heat shock 70 kDa protein
IEGPKIKM_01612 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
IEGPKIKM_01613 6.5e-190 K Psort location Cytoplasmic, score
IEGPKIKM_01615 1.2e-131 G Phosphoglycerate mutase family
IEGPKIKM_01616 8e-70 S Protein of unknown function (DUF4235)
IEGPKIKM_01617 2.3e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
IEGPKIKM_01618 1.1e-45
IEGPKIKM_01619 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
IEGPKIKM_01621 5.7e-226 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IEGPKIKM_01622 3.8e-138 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
IEGPKIKM_01623 9.9e-106 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IEGPKIKM_01624 5.1e-246 hemN H Involved in the biosynthesis of porphyrin-containing compound
IEGPKIKM_01625 3.4e-12 S Membrane
IEGPKIKM_01626 1.4e-287 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
IEGPKIKM_01627 0.0 tetP J Elongation factor G, domain IV
IEGPKIKM_01628 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
IEGPKIKM_01629 1.8e-198 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
IEGPKIKM_01630 1.2e-146 rapZ S Displays ATPase and GTPase activities
IEGPKIKM_01631 3.1e-173 whiA K May be required for sporulation
IEGPKIKM_01632 2e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
IEGPKIKM_01633 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IEGPKIKM_01634 8e-33 secG U Preprotein translocase SecG subunit
IEGPKIKM_01635 9.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IEGPKIKM_01636 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
IEGPKIKM_01637 2e-242 mepA_6 V MatE
IEGPKIKM_01639 3.5e-138 brnQ U Component of the transport system for branched-chain amino acids
IEGPKIKM_01640 1.1e-149 KLT Protein tyrosine kinase
IEGPKIKM_01641 1.4e-150 O Thioredoxin
IEGPKIKM_01643 9.1e-212 S G5
IEGPKIKM_01644 2.1e-166 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IEGPKIKM_01645 6.7e-166 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IEGPKIKM_01646 4.4e-112 S LytR cell envelope-related transcriptional attenuator
IEGPKIKM_01647 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
IEGPKIKM_01648 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
IEGPKIKM_01649 0.0 M Conserved repeat domain
IEGPKIKM_01650 0.0 murJ KLT MviN-like protein
IEGPKIKM_01651 1e-202 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IEGPKIKM_01652 9.8e-242 parB K Belongs to the ParB family
IEGPKIKM_01653 8.5e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
IEGPKIKM_01654 6.5e-125 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IEGPKIKM_01655 1.5e-92 jag S Putative single-stranded nucleic acids-binding domain
IEGPKIKM_01656 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
IEGPKIKM_01657 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IEGPKIKM_01658 4.1e-300 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IEGPKIKM_01659 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IEGPKIKM_01660 2.1e-241 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IEGPKIKM_01661 3.2e-93 S Protein of unknown function (DUF721)
IEGPKIKM_01662 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEGPKIKM_01663 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEGPKIKM_01664 4.6e-73 S Transmembrane domain of unknown function (DUF3566)
IEGPKIKM_01665 3.2e-15 abfA1 3.2.1.55 GH51 G arabinose metabolic process
IEGPKIKM_01667 3.5e-187 G Glycosyl hydrolases family 43
IEGPKIKM_01668 3.6e-187 K Periplasmic binding protein domain
IEGPKIKM_01669 6.1e-229 I Serine aminopeptidase, S33
IEGPKIKM_01670 6.7e-09 K helix_turn _helix lactose operon repressor
IEGPKIKM_01671 9.6e-42 S Protein of unknown function (DUF2442)
IEGPKIKM_01672 3.4e-18 S Domain of unknown function (DUF4160)
IEGPKIKM_01673 1.4e-14 K Helix-turn-helix domain
IEGPKIKM_01676 2.2e-179 K Cell envelope-related transcriptional attenuator domain
IEGPKIKM_01677 0.0 D FtsK/SpoIIIE family
IEGPKIKM_01678 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
IEGPKIKM_01679 7.3e-286 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
IEGPKIKM_01680 2e-142 yplQ S Haemolysin-III related
IEGPKIKM_01681 1.7e-105
IEGPKIKM_01683 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IEGPKIKM_01684 4.5e-24 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
IEGPKIKM_01685 3.1e-95 rpsA J Ribosomal protein S1
IEGPKIKM_01686 4.5e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IEGPKIKM_01687 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IEGPKIKM_01688 1.7e-179 terC P Integral membrane protein, TerC family
IEGPKIKM_01689 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
IEGPKIKM_01690 6.7e-110 aspA 3.6.1.13 L NUDIX domain
IEGPKIKM_01692 9.2e-120 pdtaR T Response regulator receiver domain protein
IEGPKIKM_01695 6.6e-180 S Prophage endopeptidase tail
IEGPKIKM_01696 1.1e-69 S phage tail
IEGPKIKM_01697 8.8e-83 NT phage tail tape measure protein
IEGPKIKM_01698 6.4e-29
IEGPKIKM_01699 9.9e-28
IEGPKIKM_01700 5.9e-59 eae N domain, Protein
IEGPKIKM_01701 6.6e-86 L protein secretion by the type IV secretion system
IEGPKIKM_01703 1.3e-115 S AIPR protein
IEGPKIKM_01704 1.9e-13
IEGPKIKM_01705 2.1e-84 pin L Resolvase, N terminal domain
IEGPKIKM_01706 1.6e-18 L Helix-turn-helix domain
IEGPKIKM_01707 4.4e-18 S Protein of unknown function (DUF2442)
IEGPKIKM_01708 2.6e-16 K Helix-turn-helix domain
IEGPKIKM_01709 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
IEGPKIKM_01710 1.3e-87
IEGPKIKM_01711 2.5e-203 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IEGPKIKM_01712 5.7e-214 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IEGPKIKM_01713 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IEGPKIKM_01714 3.3e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
IEGPKIKM_01715 3.3e-183 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IEGPKIKM_01716 2.4e-33 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IEGPKIKM_01717 6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IEGPKIKM_01718 1.3e-47 3.4.23.43 S Type IV leader peptidase family
IEGPKIKM_01719 2.1e-187 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IEGPKIKM_01720 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IEGPKIKM_01721 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IEGPKIKM_01722 1.1e-36
IEGPKIKM_01723 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
IEGPKIKM_01724 2.5e-129 pgm3 G Phosphoglycerate mutase family
IEGPKIKM_01725 1.8e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
IEGPKIKM_01726 0.0 comE S Competence protein
IEGPKIKM_01727 4.7e-90 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
IEGPKIKM_01728 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IEGPKIKM_01729 4e-69 ET Bacterial periplasmic substrate-binding proteins
IEGPKIKM_01730 2.4e-182 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
IEGPKIKM_01734 0.0 clpC O ATPase family associated with various cellular activities (AAA)
IEGPKIKM_01735 3e-184 uspA T Belongs to the universal stress protein A family
IEGPKIKM_01736 3.3e-192 S Protein of unknown function (DUF3027)
IEGPKIKM_01737 1e-66 cspB K 'Cold-shock' DNA-binding domain
IEGPKIKM_01738 1.9e-22 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
IEGPKIKM_01739 4.2e-164 EG EamA-like transporter family
IEGPKIKM_01741 2.7e-125 V FtsX-like permease family
IEGPKIKM_01742 7.5e-147 S Sulfite exporter TauE/SafE
IEGPKIKM_01744 4.4e-216 MA20_36090 S Psort location Cytoplasmic, score 8.87
IEGPKIKM_01745 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
IEGPKIKM_01746 9.3e-36 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
IEGPKIKM_01747 2.3e-76 EGP Major facilitator superfamily
IEGPKIKM_01748 3.5e-108 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IEGPKIKM_01749 4.2e-09 S Domain of unknown function (DUF4339)
IEGPKIKM_01750 2.2e-80
IEGPKIKM_01751 6.8e-71 XK27_07020 S Domain of unknown function (DUF1846)
IEGPKIKM_01752 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IEGPKIKM_01753 9.8e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IEGPKIKM_01754 1.2e-199 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IEGPKIKM_01755 1.3e-54 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IEGPKIKM_01756 0.0 V FtsX-like permease family
IEGPKIKM_01757 2.2e-128 V ABC transporter
IEGPKIKM_01758 1.7e-99 K Transcriptional regulator C-terminal region
IEGPKIKM_01759 1.3e-274 aroP E aromatic amino acid transport protein AroP K03293
IEGPKIKM_01760 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
IEGPKIKM_01761 8.8e-184 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
IEGPKIKM_01762 8.2e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IEGPKIKM_01763 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IEGPKIKM_01764 5e-254 yhjE EGP Sugar (and other) transporter
IEGPKIKM_01765 1.1e-298 scrT G Transporter major facilitator family protein
IEGPKIKM_01766 6.8e-72 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
IEGPKIKM_01767 2.1e-196 K helix_turn _helix lactose operon repressor
IEGPKIKM_01768 1.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEGPKIKM_01769 2.2e-163 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEGPKIKM_01770 1.7e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IEGPKIKM_01771 3.6e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
IEGPKIKM_01772 5.6e-247 3.5.1.104 G Polysaccharide deacetylase
IEGPKIKM_01773 4.9e-57 K Cro/C1-type HTH DNA-binding domain
IEGPKIKM_01774 2e-12 E IrrE N-terminal-like domain
IEGPKIKM_01775 3.9e-50 E IrrE N-terminal-like domain
IEGPKIKM_01776 6.8e-65
IEGPKIKM_01777 1.9e-61
IEGPKIKM_01779 2.3e-127 S Domain of unknown function (DUF4417)
IEGPKIKM_01780 2.9e-43 S Bacterial mobilisation protein (MobC)
IEGPKIKM_01781 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
IEGPKIKM_01783 2e-169 htpX O Belongs to the peptidase M48B family
IEGPKIKM_01784 5e-273 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
IEGPKIKM_01785 0.0 cadA P E1-E2 ATPase
IEGPKIKM_01786 1e-241 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
IEGPKIKM_01787 3.5e-257 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IEGPKIKM_01789 1.2e-118 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IEGPKIKM_01790 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
IEGPKIKM_01791 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
IEGPKIKM_01792 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
IEGPKIKM_01793 1.8e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEGPKIKM_01794 4e-173 S Bacterial protein of unknown function (DUF881)
IEGPKIKM_01795 2.6e-31 sbp S Protein of unknown function (DUF1290)
IEGPKIKM_01796 1.2e-141 S Bacterial protein of unknown function (DUF881)
IEGPKIKM_01797 7.3e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
IEGPKIKM_01798 2.7e-120 K helix_turn_helix, mercury resistance
IEGPKIKM_01799 7.3e-62
IEGPKIKM_01801 2.1e-117 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
IEGPKIKM_01802 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IEGPKIKM_01803 2.1e-160 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEGPKIKM_01804 2.5e-127 ybbL V ATPases associated with a variety of cellular activities
IEGPKIKM_01805 2.5e-136 ybbM V Uncharacterised protein family (UPF0014)
IEGPKIKM_01806 3e-53 IQ oxidoreductase activity
IEGPKIKM_01808 6.1e-79 K AraC-like ligand binding domain
IEGPKIKM_01809 8.1e-238 rutG F Permease family
IEGPKIKM_01811 1.2e-65 L Helix-turn-helix domain
IEGPKIKM_01812 4.4e-127 insK L Integrase core domain
IEGPKIKM_01813 2.3e-192
IEGPKIKM_01814 7.4e-15 L PFAM Integrase catalytic
IEGPKIKM_01815 5.4e-144 L IstB-like ATP binding protein
IEGPKIKM_01816 1.7e-110 L PFAM Integrase catalytic
IEGPKIKM_01817 8.8e-190 L PFAM Integrase catalytic
IEGPKIKM_01818 0.0 lhr L DEAD DEAH box helicase
IEGPKIKM_01819 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
IEGPKIKM_01820 8.6e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
IEGPKIKM_01821 1.2e-135 S UPF0126 domain
IEGPKIKM_01822 2.8e-119 3.1.4.37 T RNA ligase
IEGPKIKM_01823 2.9e-46 S phosphoesterase or phosphohydrolase
IEGPKIKM_01824 1.8e-225 ilvE 2.6.1.42 E Amino-transferase class IV
IEGPKIKM_01825 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IEGPKIKM_01826 4.8e-190 S alpha beta
IEGPKIKM_01827 9e-180 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IEGPKIKM_01828 2.1e-134 L Protein of unknown function (DUF1524)
IEGPKIKM_01829 5.5e-226 mntH P H( )-stimulated, divalent metal cation uptake system
IEGPKIKM_01830 1.5e-305 EGP Major facilitator Superfamily
IEGPKIKM_01831 2.5e-233
IEGPKIKM_01832 5.1e-102 carD K CarD-like/TRCF domain
IEGPKIKM_01833 1.9e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IEGPKIKM_01834 4.3e-139 znuB U ABC 3 transport family
IEGPKIKM_01835 1.8e-164 znuC P ATPases associated with a variety of cellular activities
IEGPKIKM_01836 2.5e-173 P Zinc-uptake complex component A periplasmic
IEGPKIKM_01837 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IEGPKIKM_01838 1.6e-132 rpsA J Ribosomal protein S1
IEGPKIKM_01840 8.1e-09 S Sucrose-6F-phosphate phosphohydrolase
IEGPKIKM_01841 2.3e-161 S Sucrose-6F-phosphate phosphohydrolase
IEGPKIKM_01842 2.3e-240 S Putative ABC-transporter type IV
IEGPKIKM_01843 7e-81
IEGPKIKM_01844 6.2e-35 Q phosphatase activity
IEGPKIKM_01845 1.2e-295 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
IEGPKIKM_01846 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IEGPKIKM_01847 5.9e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IEGPKIKM_01848 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
IEGPKIKM_01849 9.7e-118 safC S O-methyltransferase
IEGPKIKM_01850 6.6e-184 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
IEGPKIKM_01851 1.1e-70 yraN L Belongs to the UPF0102 family
IEGPKIKM_01852 7.7e-22 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IEGPKIKM_01853 2.4e-228 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IEGPKIKM_01854 5.1e-74 zur P Belongs to the Fur family
IEGPKIKM_01855 1.5e-45
IEGPKIKM_01856 2.6e-154 S TIGRFAM TIGR03943 family protein
IEGPKIKM_01857 1.6e-202 ycgR S Predicted permease
IEGPKIKM_01858 2.3e-23 J Ribosomal L32p protein family
IEGPKIKM_01859 8.2e-15 rpmJ J Ribosomal protein L36
IEGPKIKM_01860 2e-42 rpmE2 J Ribosomal protein L31
IEGPKIKM_01861 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IEGPKIKM_01862 5.5e-48 rpmB J Ribosomal L28 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)