ORF_ID e_value Gene_name EC_number CAZy COGs Description
OFKINFCL_00001 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OFKINFCL_00002 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OFKINFCL_00003 2.4e-33 yaaA S S4 domain
OFKINFCL_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OFKINFCL_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
OFKINFCL_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OFKINFCL_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OFKINFCL_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
OFKINFCL_00011 3.9e-181 yaaC S YaaC-like Protein
OFKINFCL_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
OFKINFCL_00013 1.5e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OFKINFCL_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OFKINFCL_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OFKINFCL_00016 1.2e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OFKINFCL_00017 1.3e-09
OFKINFCL_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
OFKINFCL_00019 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
OFKINFCL_00020 1.4e-213 yaaH M Glycoside Hydrolase Family
OFKINFCL_00021 2.5e-95 yaaI Q COG1335 Amidases related to nicotinamidase
OFKINFCL_00022 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OFKINFCL_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OFKINFCL_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OFKINFCL_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OFKINFCL_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
OFKINFCL_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
OFKINFCL_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
OFKINFCL_00031 1.7e-30 csfB S Inhibitor of sigma-G Gin
OFKINFCL_00032 6.8e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
OFKINFCL_00033 8.4e-202 yaaN P Belongs to the TelA family
OFKINFCL_00034 8.7e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
OFKINFCL_00035 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OFKINFCL_00036 2.2e-54 yaaQ S protein conserved in bacteria
OFKINFCL_00037 1.5e-71 yaaR S protein conserved in bacteria
OFKINFCL_00038 2.2e-182 holB 2.7.7.7 L DNA polymerase III
OFKINFCL_00039 6.1e-146 yaaT S stage 0 sporulation protein
OFKINFCL_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
OFKINFCL_00041 4.2e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
OFKINFCL_00042 1.5e-49 yazA L endonuclease containing a URI domain
OFKINFCL_00043 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OFKINFCL_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
OFKINFCL_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OFKINFCL_00046 1.2e-143 tatD L hydrolase, TatD
OFKINFCL_00047 9.5e-194 rpfB GH23 T protein conserved in bacteria
OFKINFCL_00048 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OFKINFCL_00049 2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OFKINFCL_00050 1.6e-136 yabG S peptidase
OFKINFCL_00051 7.8e-39 veg S protein conserved in bacteria
OFKINFCL_00052 8.3e-27 sspF S DNA topological change
OFKINFCL_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OFKINFCL_00054 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OFKINFCL_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
OFKINFCL_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
OFKINFCL_00057 2.5e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OFKINFCL_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OFKINFCL_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OFKINFCL_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OFKINFCL_00061 2.4e-39 yabK S Peptide ABC transporter permease
OFKINFCL_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OFKINFCL_00063 1.5e-92 spoVT K stage V sporulation protein
OFKINFCL_00064 1.1e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OFKINFCL_00065 1.1e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
OFKINFCL_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
OFKINFCL_00067 1.5e-49 yabP S Sporulation protein YabP
OFKINFCL_00068 9.5e-107 yabQ S spore cortex biosynthesis protein
OFKINFCL_00069 1.1e-44 divIC D Septum formation initiator
OFKINFCL_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
OFKINFCL_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
OFKINFCL_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
OFKINFCL_00075 1.9e-186 KLT serine threonine protein kinase
OFKINFCL_00076 4.7e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OFKINFCL_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OFKINFCL_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OFKINFCL_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OFKINFCL_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OFKINFCL_00081 3.4e-152 yacD 5.2.1.8 O peptidyl-prolyl isomerase
OFKINFCL_00082 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OFKINFCL_00083 1.5e-269 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OFKINFCL_00084 3.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
OFKINFCL_00085 2.3e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
OFKINFCL_00086 8.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OFKINFCL_00087 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OFKINFCL_00088 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OFKINFCL_00089 4.1e-30 yazB K transcriptional
OFKINFCL_00090 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OFKINFCL_00091 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OFKINFCL_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
OFKINFCL_00097 2e-08
OFKINFCL_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
OFKINFCL_00103 2.9e-76 ctsR K Belongs to the CtsR family
OFKINFCL_00104 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
OFKINFCL_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
OFKINFCL_00106 0.0 clpC O Belongs to the ClpA ClpB family
OFKINFCL_00107 3.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OFKINFCL_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OFKINFCL_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
OFKINFCL_00110 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
OFKINFCL_00111 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
OFKINFCL_00112 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OFKINFCL_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
OFKINFCL_00114 1.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OFKINFCL_00115 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OFKINFCL_00116 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OFKINFCL_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
OFKINFCL_00118 4.4e-115 sigH K Belongs to the sigma-70 factor family
OFKINFCL_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OFKINFCL_00120 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
OFKINFCL_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OFKINFCL_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OFKINFCL_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OFKINFCL_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OFKINFCL_00125 3.1e-107 rsmC 2.1.1.172 J Methyltransferase
OFKINFCL_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OFKINFCL_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OFKINFCL_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
OFKINFCL_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OFKINFCL_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OFKINFCL_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OFKINFCL_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OFKINFCL_00133 4.5e-177 ybaC 3.4.11.5 S Alpha/beta hydrolase family
OFKINFCL_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
OFKINFCL_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OFKINFCL_00136 3e-105 rplD J Forms part of the polypeptide exit tunnel
OFKINFCL_00137 2.6e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OFKINFCL_00138 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OFKINFCL_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OFKINFCL_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OFKINFCL_00141 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OFKINFCL_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OFKINFCL_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
OFKINFCL_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OFKINFCL_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OFKINFCL_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OFKINFCL_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OFKINFCL_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OFKINFCL_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OFKINFCL_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OFKINFCL_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OFKINFCL_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OFKINFCL_00153 1.9e-23 rpmD J Ribosomal protein L30
OFKINFCL_00154 1.8e-72 rplO J binds to the 23S rRNA
OFKINFCL_00155 5.5e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OFKINFCL_00156 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OFKINFCL_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
OFKINFCL_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OFKINFCL_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
OFKINFCL_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OFKINFCL_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OFKINFCL_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OFKINFCL_00163 3.6e-58 rplQ J Ribosomal protein L17
OFKINFCL_00164 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OFKINFCL_00165 3.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OFKINFCL_00166 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OFKINFCL_00167 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OFKINFCL_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OFKINFCL_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
OFKINFCL_00170 6.9e-144 ybaJ Q Methyltransferase domain
OFKINFCL_00171 9.7e-66 ybaK S Protein of unknown function (DUF2521)
OFKINFCL_00172 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OFKINFCL_00173 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
OFKINFCL_00174 1.2e-84 gerD
OFKINFCL_00175 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
OFKINFCL_00176 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
OFKINFCL_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
OFKINFCL_00180 2e-08
OFKINFCL_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
OFKINFCL_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
OFKINFCL_00186 6.8e-18 S ORF located using Blastx
OFKINFCL_00187 1.5e-245 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
OFKINFCL_00189 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
OFKINFCL_00190 5.4e-141 ybbA S Putative esterase
OFKINFCL_00191 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFKINFCL_00192 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFKINFCL_00193 1.4e-165 feuA P Iron-uptake system-binding protein
OFKINFCL_00194 9.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
OFKINFCL_00195 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
OFKINFCL_00196 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
OFKINFCL_00197 1.1e-250 yfeW 3.4.16.4 V Belongs to the UPF0214 family
OFKINFCL_00198 4.9e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFKINFCL_00199 1.2e-149 ybbH K transcriptional
OFKINFCL_00200 2.3e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OFKINFCL_00201 1.9e-86 ybbJ J acetyltransferase
OFKINFCL_00202 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
OFKINFCL_00208 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
OFKINFCL_00209 5.3e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
OFKINFCL_00210 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OFKINFCL_00211 3e-225 ybbR S protein conserved in bacteria
OFKINFCL_00212 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OFKINFCL_00213 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OFKINFCL_00214 1.6e-171 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OFKINFCL_00215 4.4e-120 adaA 3.2.2.21 K Transcriptional regulator
OFKINFCL_00216 1.4e-98 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OFKINFCL_00217 9.1e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OFKINFCL_00218 0.0 ybcC S Belongs to the UPF0753 family
OFKINFCL_00219 2.7e-91 can 4.2.1.1 P carbonic anhydrase
OFKINFCL_00220 8.7e-47
OFKINFCL_00221 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
OFKINFCL_00222 5.1e-50 ybzH K Helix-turn-helix domain
OFKINFCL_00223 4.5e-203 ybcL EGP Major facilitator Superfamily
OFKINFCL_00224 3.3e-56
OFKINFCL_00225 5.3e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OFKINFCL_00226 1.5e-123 T Transcriptional regulatory protein, C terminal
OFKINFCL_00227 2e-167 T His Kinase A (phospho-acceptor) domain
OFKINFCL_00229 3e-139 KLT Protein tyrosine kinase
OFKINFCL_00230 8.5e-151 ybdN
OFKINFCL_00231 2.2e-213 ybdO S Domain of unknown function (DUF4885)
OFKINFCL_00232 5.8e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
OFKINFCL_00233 4.8e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
OFKINFCL_00234 4.9e-30 ybxH S Family of unknown function (DUF5370)
OFKINFCL_00235 1.2e-149 ybxI 3.5.2.6 V beta-lactamase
OFKINFCL_00236 7.3e-244 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
OFKINFCL_00237 4.9e-41 ybyB
OFKINFCL_00238 1.8e-290 ybeC E amino acid
OFKINFCL_00239 7.6e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OFKINFCL_00240 7.3e-258 glpT G -transporter
OFKINFCL_00241 1.5e-34 S Protein of unknown function (DUF2651)
OFKINFCL_00242 2.8e-168 ybfA 3.4.15.5 K FR47-like protein
OFKINFCL_00243 4.8e-219 ybfB G COG0477 Permeases of the major facilitator superfamily
OFKINFCL_00244 5.7e-161 ybfH EG EamA-like transporter family
OFKINFCL_00245 2.3e-145 msmR K AraC-like ligand binding domain
OFKINFCL_00246 3.7e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OFKINFCL_00247 2e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
OFKINFCL_00249 6.7e-167 S Alpha/beta hydrolase family
OFKINFCL_00250 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OFKINFCL_00251 2.7e-85 ybfM S SNARE associated Golgi protein
OFKINFCL_00252 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
OFKINFCL_00253 1.3e-44 ybfN
OFKINFCL_00254 2.5e-250 S Erythromycin esterase
OFKINFCL_00255 6.7e-167 ybfP K Transcriptional regulator
OFKINFCL_00256 3.9e-192 yceA S Belongs to the UPF0176 family
OFKINFCL_00257 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OFKINFCL_00258 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFKINFCL_00259 8e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OFKINFCL_00260 4.9e-128 K UTRA
OFKINFCL_00262 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OFKINFCL_00263 3.3e-261 mmuP E amino acid
OFKINFCL_00264 2.3e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
OFKINFCL_00266 2.8e-255 agcS E Sodium alanine symporter
OFKINFCL_00267 1.9e-186 glsA 3.5.1.2 E Belongs to the glutaminase family
OFKINFCL_00268 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
OFKINFCL_00269 2.6e-169 glnL T Regulator
OFKINFCL_00270 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
OFKINFCL_00271 3.4e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OFKINFCL_00272 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
OFKINFCL_00273 1.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OFKINFCL_00274 1.5e-124 ycbG K FCD
OFKINFCL_00275 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
OFKINFCL_00276 1.5e-174 ycbJ S Macrolide 2'-phosphotransferase
OFKINFCL_00277 1.3e-23 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
OFKINFCL_00278 1.9e-167 eamA1 EG spore germination
OFKINFCL_00279 2.2e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFKINFCL_00280 3.4e-169 T PhoQ Sensor
OFKINFCL_00281 3.8e-165 ycbN V ABC transporter, ATP-binding protein
OFKINFCL_00282 6.7e-114 S ABC-2 family transporter protein
OFKINFCL_00283 8.2e-53 ycbP S Protein of unknown function (DUF2512)
OFKINFCL_00284 1.3e-78 sleB 3.5.1.28 M Cell wall
OFKINFCL_00285 1.9e-135 ycbR T vWA found in TerF C terminus
OFKINFCL_00286 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
OFKINFCL_00287 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OFKINFCL_00288 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OFKINFCL_00289 2.5e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OFKINFCL_00290 1.1e-203 ycbU E Selenocysteine lyase
OFKINFCL_00291 3e-225 lmrB EGP the major facilitator superfamily
OFKINFCL_00292 1.6e-100 yxaF K Transcriptional regulator
OFKINFCL_00293 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
OFKINFCL_00294 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OFKINFCL_00295 4.5e-59 S RDD family
OFKINFCL_00296 2.1e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
OFKINFCL_00297 2.9e-160 2.7.13.3 T GHKL domain
OFKINFCL_00298 1.2e-126 lytR_2 T LytTr DNA-binding domain
OFKINFCL_00299 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
OFKINFCL_00300 3.2e-201 natB CP ABC-2 family transporter protein
OFKINFCL_00301 1e-173 yccK C Aldo keto reductase
OFKINFCL_00302 6.6e-177 ycdA S Domain of unknown function (DUF5105)
OFKINFCL_00303 4.1e-275 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
OFKINFCL_00304 2.5e-259 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
OFKINFCL_00305 2.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
OFKINFCL_00306 1.2e-173 S response regulator aspartate phosphatase
OFKINFCL_00307 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
OFKINFCL_00308 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
OFKINFCL_00309 2.1e-166 adcA P Belongs to the bacterial solute-binding protein 9 family
OFKINFCL_00310 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OFKINFCL_00311 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OFKINFCL_00312 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFKINFCL_00313 2.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
OFKINFCL_00314 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
OFKINFCL_00315 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
OFKINFCL_00316 1.4e-136 terC P Protein of unknown function (DUF475)
OFKINFCL_00317 0.0 yceG S Putative component of 'biosynthetic module'
OFKINFCL_00318 2e-192 yceH P Belongs to the TelA family
OFKINFCL_00319 3e-218 naiP P Uncharacterised MFS-type transporter YbfB
OFKINFCL_00320 1.8e-207 yceJ EGP Uncharacterised MFS-type transporter YbfB
OFKINFCL_00321 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
OFKINFCL_00322 1.9e-228 proV 3.6.3.32 E glycine betaine
OFKINFCL_00323 1.3e-127 opuAB P glycine betaine
OFKINFCL_00324 1.5e-163 opuAC E glycine betaine
OFKINFCL_00325 2.4e-217 amhX S amidohydrolase
OFKINFCL_00326 8.7e-257 ycgA S Membrane
OFKINFCL_00327 4.1e-81 ycgB
OFKINFCL_00328 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
OFKINFCL_00329 4e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OFKINFCL_00330 5.5e-184 lctP C L-lactate permease
OFKINFCL_00331 5.8e-95 lctP C L-lactate permease
OFKINFCL_00332 3.9e-263 mdr EGP Major facilitator Superfamily
OFKINFCL_00333 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
OFKINFCL_00334 6.8e-113 ycgF E Lysine exporter protein LysE YggA
OFKINFCL_00335 1.3e-150 yqcI S YqcI/YcgG family
OFKINFCL_00336 3.1e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
OFKINFCL_00337 2.4e-112 ycgI S Domain of unknown function (DUF1989)
OFKINFCL_00338 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OFKINFCL_00339 4.7e-108 tmrB S AAA domain
OFKINFCL_00341 1.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OFKINFCL_00342 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
OFKINFCL_00343 3.2e-178 oxyR3 K LysR substrate binding domain
OFKINFCL_00344 8e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
OFKINFCL_00345 1.6e-143 ycgL S Predicted nucleotidyltransferase
OFKINFCL_00346 5.1e-170 ycgM E Proline dehydrogenase
OFKINFCL_00347 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OFKINFCL_00348 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OFKINFCL_00349 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
OFKINFCL_00350 1.4e-145 ycgQ S membrane
OFKINFCL_00351 1.2e-139 ycgR S permeases
OFKINFCL_00352 1.1e-158 I alpha/beta hydrolase fold
OFKINFCL_00353 2.2e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
OFKINFCL_00354 1.5e-272 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OFKINFCL_00355 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
OFKINFCL_00356 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OFKINFCL_00357 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OFKINFCL_00358 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
OFKINFCL_00359 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
OFKINFCL_00360 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
OFKINFCL_00361 6.1e-108 yciB M ErfK YbiS YcfS YnhG
OFKINFCL_00362 1.3e-226 yciC S GTPases (G3E family)
OFKINFCL_00363 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
OFKINFCL_00364 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
OFKINFCL_00366 7.8e-52 yckD S Protein of unknown function (DUF2680)
OFKINFCL_00367 5.7e-39 K MarR family
OFKINFCL_00368 2.3e-22
OFKINFCL_00369 2.6e-66 S AAA domain
OFKINFCL_00370 1.7e-45 S AAA domain
OFKINFCL_00371 4.9e-292 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFKINFCL_00372 1.1e-68 nin S Competence protein J (ComJ)
OFKINFCL_00373 3.5e-71 nucA M Deoxyribonuclease NucA/NucB
OFKINFCL_00374 3.9e-187 tlpC 2.7.13.3 NT chemotaxis protein
OFKINFCL_00375 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
OFKINFCL_00376 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
OFKINFCL_00377 1.3e-63 hxlR K transcriptional
OFKINFCL_00378 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFKINFCL_00379 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFKINFCL_00380 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
OFKINFCL_00381 5.7e-140 srfAD Q thioesterase
OFKINFCL_00382 1.5e-225 EGP Major Facilitator Superfamily
OFKINFCL_00383 1.2e-84 S YcxB-like protein
OFKINFCL_00384 3.8e-160 ycxC EG EamA-like transporter family
OFKINFCL_00385 8e-58 ycxD K GntR family transcriptional regulator
OFKINFCL_00386 1.1e-144 ycxD K GntR family transcriptional regulator
OFKINFCL_00387 2.9e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
OFKINFCL_00388 9.7e-115 yczE S membrane
OFKINFCL_00389 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OFKINFCL_00390 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
OFKINFCL_00391 4.1e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
OFKINFCL_00392 1.9e-161 bsdA K LysR substrate binding domain
OFKINFCL_00393 4.9e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
OFKINFCL_00394 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
OFKINFCL_00395 4e-39 bsdD 4.1.1.61 S response to toxic substance
OFKINFCL_00396 3.5e-82 yclD
OFKINFCL_00397 4.4e-160 yclE 3.4.11.5 S Alpha beta hydrolase
OFKINFCL_00398 4.7e-266 dtpT E amino acid peptide transporter
OFKINFCL_00399 3.2e-306 yclG M Pectate lyase superfamily protein
OFKINFCL_00401 4.4e-281 gerKA EG Spore germination protein
OFKINFCL_00402 1.3e-232 gerKC S spore germination
OFKINFCL_00403 1.7e-199 gerKB F Spore germination protein
OFKINFCL_00404 1.5e-121 yclH P ABC transporter
OFKINFCL_00405 4e-201 yclI V ABC transporter (permease) YclI
OFKINFCL_00406 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFKINFCL_00407 9.8e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
OFKINFCL_00408 5.2e-71 S aspartate phosphatase
OFKINFCL_00411 1.7e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
OFKINFCL_00412 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFKINFCL_00413 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFKINFCL_00414 6.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
OFKINFCL_00415 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
OFKINFCL_00416 4.1e-251 ycnB EGP Major facilitator Superfamily
OFKINFCL_00417 1.6e-152 ycnC K Transcriptional regulator
OFKINFCL_00418 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
OFKINFCL_00419 1.6e-45 ycnE S Monooxygenase
OFKINFCL_00420 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
OFKINFCL_00421 2.5e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFKINFCL_00422 3.7e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OFKINFCL_00423 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OFKINFCL_00424 6.1e-149 glcU U Glucose uptake
OFKINFCL_00425 6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFKINFCL_00426 1.4e-99 ycnI S protein conserved in bacteria
OFKINFCL_00427 2.3e-306 ycnJ P protein, homolog of Cu resistance protein CopC
OFKINFCL_00428 2.8e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
OFKINFCL_00429 3.4e-53
OFKINFCL_00430 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
OFKINFCL_00431 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
OFKINFCL_00432 6.9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
OFKINFCL_00433 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
OFKINFCL_00434 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OFKINFCL_00435 7.1e-74 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OFKINFCL_00436 2e-106 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
OFKINFCL_00437 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
OFKINFCL_00439 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OFKINFCL_00440 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
OFKINFCL_00441 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
OFKINFCL_00442 1.8e-147 ycsI S Belongs to the D-glutamate cyclase family
OFKINFCL_00443 1.4e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
OFKINFCL_00444 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
OFKINFCL_00445 6e-132 kipR K Transcriptional regulator
OFKINFCL_00446 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
OFKINFCL_00448 8e-47 yczJ S biosynthesis
OFKINFCL_00449 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
OFKINFCL_00450 1.7e-173 ydhF S Oxidoreductase
OFKINFCL_00451 0.0 mtlR K transcriptional regulator, MtlR
OFKINFCL_00452 7.1e-294 ydaB IQ acyl-CoA ligase
OFKINFCL_00453 4.5e-98 ydaC Q Methyltransferase domain
OFKINFCL_00454 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFKINFCL_00455 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
OFKINFCL_00456 5.4e-98 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OFKINFCL_00457 6.8e-77 ydaG 1.4.3.5 S general stress protein
OFKINFCL_00458 7.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
OFKINFCL_00459 3.3e-46 ydzA EGP Major facilitator Superfamily
OFKINFCL_00460 2.5e-74 lrpC K Transcriptional regulator
OFKINFCL_00461 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OFKINFCL_00462 1.2e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
OFKINFCL_00463 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
OFKINFCL_00464 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
OFKINFCL_00465 1.3e-232 ydaM M Glycosyl transferase family group 2
OFKINFCL_00466 0.0 ydaN S Bacterial cellulose synthase subunit
OFKINFCL_00467 0.0 ydaO E amino acid
OFKINFCL_00468 3.9e-78 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
OFKINFCL_00469 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OFKINFCL_00470 2.1e-39
OFKINFCL_00471 8.6e-224 mntH P H( )-stimulated, divalent metal cation uptake system
OFKINFCL_00473 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
OFKINFCL_00474 2.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
OFKINFCL_00476 8.9e-59 ydbB G Cupin domain
OFKINFCL_00477 1.1e-62 ydbC S Domain of unknown function (DUF4937
OFKINFCL_00478 6.7e-153 ydbD P Catalase
OFKINFCL_00479 7.9e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
OFKINFCL_00480 2.4e-295 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OFKINFCL_00481 2.3e-119 dctR T COG4565 Response regulator of citrate malate metabolism
OFKINFCL_00482 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OFKINFCL_00483 3.7e-180 ydbI S AI-2E family transporter
OFKINFCL_00484 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
OFKINFCL_00485 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OFKINFCL_00486 2.7e-52 ydbL
OFKINFCL_00487 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
OFKINFCL_00488 1.1e-18 S Fur-regulated basic protein B
OFKINFCL_00489 2.2e-07 S Fur-regulated basic protein A
OFKINFCL_00490 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OFKINFCL_00491 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OFKINFCL_00492 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OFKINFCL_00493 1.1e-253 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OFKINFCL_00494 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OFKINFCL_00495 2.1e-82 ydbS S Bacterial PH domain
OFKINFCL_00496 5.1e-260 ydbT S Membrane
OFKINFCL_00497 4.5e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
OFKINFCL_00498 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OFKINFCL_00499 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
OFKINFCL_00500 1.3e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OFKINFCL_00501 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
OFKINFCL_00502 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
OFKINFCL_00503 3.7e-143 rsbR T Positive regulator of sigma-B
OFKINFCL_00504 5.2e-57 rsbS T antagonist
OFKINFCL_00505 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
OFKINFCL_00506 7.1e-189 rsbU 3.1.3.3 KT phosphatase
OFKINFCL_00507 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
OFKINFCL_00508 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
OFKINFCL_00509 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFKINFCL_00510 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
OFKINFCL_00514 1.5e-82 ydcG S EVE domain
OFKINFCL_00515 1e-75 ydcH K helix_turn_helix multiple antibiotic resistance protein
OFKINFCL_00516 0.0 yhgF K COG2183 Transcriptional accessory protein
OFKINFCL_00517 8.9e-83 ydcK S Belongs to the SprT family
OFKINFCL_00526 3.4e-33 K Helix-turn-helix XRE-family like proteins
OFKINFCL_00527 9.6e-40
OFKINFCL_00528 5.4e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
OFKINFCL_00529 8.7e-30 cspL K Cold shock
OFKINFCL_00530 6.1e-79 carD K Transcription factor
OFKINFCL_00531 2e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OFKINFCL_00532 1.4e-164 rhaS5 K AraC-like ligand binding domain
OFKINFCL_00533 4.9e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OFKINFCL_00534 1.8e-164 ydeE K AraC family transcriptional regulator
OFKINFCL_00535 4.3e-261 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFKINFCL_00536 1.8e-216 ydeG EGP Major facilitator superfamily
OFKINFCL_00537 1.4e-44 ydeH
OFKINFCL_00538 3.2e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
OFKINFCL_00539 4.8e-109
OFKINFCL_00540 1.1e-31 S SNARE associated Golgi protein
OFKINFCL_00541 1.8e-14 ptsH G PTS HPr component phosphorylation site
OFKINFCL_00542 8.8e-85 K Transcriptional regulator C-terminal region
OFKINFCL_00543 1.8e-153 ydeK EG -transporter
OFKINFCL_00544 6.4e-273 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFKINFCL_00545 7.1e-74 maoC I N-terminal half of MaoC dehydratase
OFKINFCL_00546 1.1e-104 ydeN S Serine hydrolase
OFKINFCL_00547 8.9e-56 K HxlR-like helix-turn-helix
OFKINFCL_00548 3.5e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OFKINFCL_00549 4.8e-69 ydeP K Transcriptional regulator
OFKINFCL_00550 5.1e-107 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
OFKINFCL_00551 3.1e-183 ydeR EGP Major facilitator Superfamily
OFKINFCL_00552 1e-102 ydeS K Transcriptional regulator
OFKINFCL_00553 2.8e-57 arsR K transcriptional
OFKINFCL_00554 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OFKINFCL_00555 2.1e-148 ydfB J GNAT acetyltransferase
OFKINFCL_00556 8.8e-162 ydfC EG EamA-like transporter family
OFKINFCL_00557 7.4e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFKINFCL_00558 1.4e-115 ydfE S Flavin reductase like domain
OFKINFCL_00559 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
OFKINFCL_00560 6.5e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OFKINFCL_00562 1.8e-175 ydfH 2.7.13.3 T Histidine kinase
OFKINFCL_00563 9.3e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFKINFCL_00564 0.0 ydfJ S drug exporters of the RND superfamily
OFKINFCL_00565 1.4e-175 S Alpha/beta hydrolase family
OFKINFCL_00566 1.9e-116 S Protein of unknown function (DUF554)
OFKINFCL_00567 9.2e-147 K Bacterial transcription activator, effector binding domain
OFKINFCL_00568 2.9e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OFKINFCL_00569 6.2e-111 ydfN C nitroreductase
OFKINFCL_00570 2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
OFKINFCL_00571 8.8e-63 mhqP S DoxX
OFKINFCL_00572 1.7e-54 traF CO Thioredoxin
OFKINFCL_00574 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
OFKINFCL_00575 6.3e-29
OFKINFCL_00577 4.4e-118 ydfR S Protein of unknown function (DUF421)
OFKINFCL_00578 5.2e-122 ydfS S Protein of unknown function (DUF421)
OFKINFCL_00579 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
OFKINFCL_00580 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
OFKINFCL_00581 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
OFKINFCL_00582 2.8e-100 K Bacterial regulatory proteins, tetR family
OFKINFCL_00583 1.6e-52 S DoxX-like family
OFKINFCL_00584 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
OFKINFCL_00585 1.6e-302 expZ S ABC transporter
OFKINFCL_00586 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
OFKINFCL_00587 1.1e-81 dinB S DinB family
OFKINFCL_00588 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
OFKINFCL_00589 0.0 ydgH S drug exporters of the RND superfamily
OFKINFCL_00590 3.4e-112 drgA C nitroreductase
OFKINFCL_00591 7.1e-69 ydgJ K Winged helix DNA-binding domain
OFKINFCL_00592 7.4e-209 tcaB EGP Major facilitator Superfamily
OFKINFCL_00593 3.5e-121 ydhB S membrane transporter protein
OFKINFCL_00594 6.5e-122 ydhC K FCD
OFKINFCL_00595 1.6e-243 ydhD M Glycosyl hydrolase
OFKINFCL_00596 2.7e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OFKINFCL_00597 6.2e-123
OFKINFCL_00598 4.2e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
OFKINFCL_00599 1.1e-67 frataxin S Domain of unknown function (DU1801)
OFKINFCL_00601 5.2e-81 K Acetyltransferase (GNAT) domain
OFKINFCL_00602 3.4e-180 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
OFKINFCL_00603 1e-96 ydhK M Protein of unknown function (DUF1541)
OFKINFCL_00604 1.8e-199 pbuE EGP Major facilitator Superfamily
OFKINFCL_00605 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
OFKINFCL_00606 4.3e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
OFKINFCL_00607 3.4e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OFKINFCL_00608 7.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFKINFCL_00609 4.3e-132 ydhQ K UTRA
OFKINFCL_00610 3e-170 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
OFKINFCL_00611 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
OFKINFCL_00612 6.2e-215 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
OFKINFCL_00613 2.3e-156 ydhU P Catalase
OFKINFCL_00616 3.4e-39 S COG NOG14552 non supervised orthologous group
OFKINFCL_00617 7.8e-08
OFKINFCL_00619 4e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OFKINFCL_00620 1.2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
OFKINFCL_00621 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
OFKINFCL_00622 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OFKINFCL_00623 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OFKINFCL_00624 0.0 ydiF S ABC transporter
OFKINFCL_00625 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
OFKINFCL_00626 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OFKINFCL_00627 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OFKINFCL_00628 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OFKINFCL_00629 2.9e-27 ydiK S Domain of unknown function (DUF4305)
OFKINFCL_00630 1.3e-128 ydiL S CAAX protease self-immunity
OFKINFCL_00631 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OFKINFCL_00632 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OFKINFCL_00633 9.8e-145 L Belongs to the 'phage' integrase family
OFKINFCL_00634 3.6e-48 xkdA E IrrE N-terminal-like domain
OFKINFCL_00635 4.7e-23 S Protein of unknown function (DUF4064)
OFKINFCL_00636 3.3e-49
OFKINFCL_00637 1.5e-16 xre K Helix-turn-helix XRE-family like proteins
OFKINFCL_00638 1.1e-12 K Helix-turn-helix domain
OFKINFCL_00639 5.3e-34
OFKINFCL_00640 8.4e-73 K BRO family, N-terminal domain
OFKINFCL_00641 7.5e-87
OFKINFCL_00646 1.2e-105 S YqaJ-like viral recombinase domain
OFKINFCL_00647 2e-110 recT L Recombinational DNA repair protein (RecE pathway)
OFKINFCL_00648 3.9e-37 3.1.3.16 L DnaD domain protein
OFKINFCL_00649 4.2e-120 xkdC L IstB-like ATP binding protein
OFKINFCL_00651 1.8e-61 rusA L Endodeoxyribonuclease RusA
OFKINFCL_00652 2.3e-25 yqaO S Phage-like element PBSX protein XtrA
OFKINFCL_00655 1.8e-62
OFKINFCL_00667 1.4e-38 L Transposase
OFKINFCL_00671 4.8e-91 yqaS L DNA packaging
OFKINFCL_00672 3.9e-216 S phage terminase, large subunit
OFKINFCL_00673 3.1e-206 S Phage portal protein, SPP1 Gp6-like
OFKINFCL_00674 2.2e-80 S Phage Mu protein F like protein
OFKINFCL_00675 2.3e-59 S Domain of unknown function (DUF4355)
OFKINFCL_00676 9.8e-145 S Phage capsid family
OFKINFCL_00679 2.4e-28 S Phage gp6-like head-tail connector protein
OFKINFCL_00680 1.8e-27 S Phage head-tail joining protein
OFKINFCL_00681 7.3e-11 S Bacteriophage HK97-gp10, putative tail-component
OFKINFCL_00682 6.2e-80 S sequence-specific DNA binding transcription factor activity
OFKINFCL_00683 2.9e-29 S Protein of unknown function (DUF3168)
OFKINFCL_00684 3e-34 S Phage tail tube protein
OFKINFCL_00685 1.3e-08 chiA 3.2.1.14 GH18 G Belongs to the glycosyl hydrolase 18 family
OFKINFCL_00686 1.4e-28 S Phage tail assembly chaperone protein, TAC
OFKINFCL_00687 4.1e-138
OFKINFCL_00688 1.3e-49
OFKINFCL_00689 4.8e-221 S peptidoglycan catabolic process
OFKINFCL_00694 8.6e-28 xhlA S Haemolysin XhlA
OFKINFCL_00695 3.9e-30 xhlB S SPP1 phage holin
OFKINFCL_00696 4e-128 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
OFKINFCL_00697 1.9e-36
OFKINFCL_00698 9e-19
OFKINFCL_00700 2.1e-25 K Helix-turn-helix domain
OFKINFCL_00701 6.6e-49 gepA S Protein of unknown function (DUF4065)
OFKINFCL_00702 7e-37
OFKINFCL_00703 2.4e-13
OFKINFCL_00704 4.8e-233 M peptidoglycan-binding domain-containing protein
OFKINFCL_00706 3.3e-57
OFKINFCL_00707 0.0 K NB-ARC domain
OFKINFCL_00708 4.7e-199 gutB 1.1.1.14 E Dehydrogenase
OFKINFCL_00709 9.6e-253 gutA G MFS/sugar transport protein
OFKINFCL_00710 6.4e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
OFKINFCL_00711 1.5e-113 pspA KT Phage shock protein A
OFKINFCL_00712 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OFKINFCL_00713 1.2e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
OFKINFCL_00714 1.8e-149 ydjI S virion core protein (lumpy skin disease virus)
OFKINFCL_00715 5.2e-195 S Ion transport 2 domain protein
OFKINFCL_00716 1.7e-257 iolT EGP Major facilitator Superfamily
OFKINFCL_00717 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OFKINFCL_00718 4.5e-64 ydjM M Lytic transglycolase
OFKINFCL_00719 3.1e-155 ydjN U Involved in the tonB-independent uptake of proteins
OFKINFCL_00720 1.4e-34 ydjO S Cold-inducible protein YdjO
OFKINFCL_00721 6.8e-158 ydjP I Alpha/beta hydrolase family
OFKINFCL_00722 1.7e-174 yeaA S Protein of unknown function (DUF4003)
OFKINFCL_00723 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
OFKINFCL_00724 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
OFKINFCL_00725 2.4e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OFKINFCL_00726 4.7e-174 yeaC S COG0714 MoxR-like ATPases
OFKINFCL_00727 2.6e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
OFKINFCL_00728 0.0 yebA E COG1305 Transglutaminase-like enzymes
OFKINFCL_00729 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OFKINFCL_00730 6.4e-88 K Belongs to the sigma-70 factor family. ECF subfamily
OFKINFCL_00731 9.8e-248 S Domain of unknown function (DUF4179)
OFKINFCL_00732 1.1e-210 pbuG S permease
OFKINFCL_00733 1.9e-115 yebC M Membrane
OFKINFCL_00735 1.7e-91 yebE S UPF0316 protein
OFKINFCL_00736 8e-28 yebG S NETI protein
OFKINFCL_00737 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OFKINFCL_00738 2.2e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OFKINFCL_00739 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OFKINFCL_00740 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
OFKINFCL_00741 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OFKINFCL_00742 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OFKINFCL_00743 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OFKINFCL_00744 2.1e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OFKINFCL_00745 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
OFKINFCL_00746 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OFKINFCL_00747 8.6e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
OFKINFCL_00748 1.3e-232 purD 6.3.4.13 F Belongs to the GARS family
OFKINFCL_00749 1.1e-71 K helix_turn_helix ASNC type
OFKINFCL_00750 7.5e-228 yjeH E Amino acid permease
OFKINFCL_00751 2.7e-27 S Protein of unknown function (DUF2892)
OFKINFCL_00752 0.0 yerA 3.5.4.2 F adenine deaminase
OFKINFCL_00753 6.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
OFKINFCL_00754 4.8e-51 yerC S protein conserved in bacteria
OFKINFCL_00755 7.9e-304 yerD 1.4.7.1 E Belongs to the glutamate synthase family
OFKINFCL_00756 8.4e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OFKINFCL_00757 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OFKINFCL_00758 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OFKINFCL_00759 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
OFKINFCL_00760 9.2e-197 yerI S homoserine kinase type II (protein kinase fold)
OFKINFCL_00761 1.6e-123 sapB S MgtC SapB transporter
OFKINFCL_00762 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OFKINFCL_00763 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OFKINFCL_00764 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OFKINFCL_00765 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OFKINFCL_00766 1.5e-147 yerO K Transcriptional regulator
OFKINFCL_00767 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OFKINFCL_00768 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OFKINFCL_00769 4.9e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OFKINFCL_00770 3.1e-196 V Domain of unknown function (DUF3578)
OFKINFCL_00771 2.9e-10 S Immunity protein 50
OFKINFCL_00772 1.5e-157 L nucleic acid phosphodiester bond hydrolysis
OFKINFCL_00773 5.1e-179 3.4.24.40 CO amine dehydrogenase activity
OFKINFCL_00774 5.5e-53
OFKINFCL_00775 1.1e-52
OFKINFCL_00776 4.1e-209 S Tetratricopeptide repeat
OFKINFCL_00778 2.7e-126 yeeN K transcriptional regulatory protein
OFKINFCL_00780 8.5e-102 dhaR3 K Transcriptional regulator
OFKINFCL_00781 2.2e-81 yesE S SnoaL-like domain
OFKINFCL_00782 3.8e-143 yesF GM NAD(P)H-binding
OFKINFCL_00783 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
OFKINFCL_00784 1.5e-45 cotJB S CotJB protein
OFKINFCL_00785 5.2e-104 cotJC P Spore Coat
OFKINFCL_00786 1.2e-102 yesJ K Acetyltransferase (GNAT) family
OFKINFCL_00787 1.8e-102 yesL S Protein of unknown function, DUF624
OFKINFCL_00788 0.0 yesM 2.7.13.3 T Histidine kinase
OFKINFCL_00789 3.4e-200 yesN K helix_turn_helix, arabinose operon control protein
OFKINFCL_00790 7.3e-247 yesO G Bacterial extracellular solute-binding protein
OFKINFCL_00791 8e-171 yesP G Binding-protein-dependent transport system inner membrane component
OFKINFCL_00792 2.4e-164 yesQ P Binding-protein-dependent transport system inner membrane component
OFKINFCL_00793 2.5e-197 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
OFKINFCL_00794 0.0 yesS K Transcriptional regulator
OFKINFCL_00795 3e-130 E GDSL-like Lipase/Acylhydrolase
OFKINFCL_00796 1e-127 yesU S Domain of unknown function (DUF1961)
OFKINFCL_00797 1e-113 yesV S Protein of unknown function, DUF624
OFKINFCL_00798 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
OFKINFCL_00799 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
OFKINFCL_00800 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
OFKINFCL_00801 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
OFKINFCL_00802 0.0 yetA
OFKINFCL_00803 4e-289 lplA G Bacterial extracellular solute-binding protein
OFKINFCL_00804 3.6e-174 lplB G COG4209 ABC-type polysaccharide transport system, permease component
OFKINFCL_00805 2.2e-162 lplC G Binding-protein-dependent transport system inner membrane component
OFKINFCL_00806 7.6e-255 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
OFKINFCL_00807 5.2e-122 yetF S membrane
OFKINFCL_00808 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
OFKINFCL_00809 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OFKINFCL_00810 2.2e-34
OFKINFCL_00811 1.6e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OFKINFCL_00812 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
OFKINFCL_00813 9.1e-105 yetJ S Belongs to the BI1 family
OFKINFCL_00814 9.2e-30 yetM CH FAD binding domain
OFKINFCL_00815 1.8e-132 M Membrane
OFKINFCL_00816 3.7e-196 yetN S Protein of unknown function (DUF3900)
OFKINFCL_00817 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OFKINFCL_00818 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OFKINFCL_00819 7.9e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
OFKINFCL_00820 3.2e-172 yfnG 4.2.1.45 M dehydratase
OFKINFCL_00821 1.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
OFKINFCL_00822 4.7e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
OFKINFCL_00823 3e-189 yfnD M Nucleotide-diphospho-sugar transferase
OFKINFCL_00824 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
OFKINFCL_00825 3.9e-133 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
OFKINFCL_00826 6.4e-241 yfnA E amino acid
OFKINFCL_00827 3.7e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OFKINFCL_00828 1.1e-113 yfmS NT chemotaxis protein
OFKINFCL_00829 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OFKINFCL_00830 3.7e-73 yfmQ S Uncharacterised protein from bacillus cereus group
OFKINFCL_00831 1.4e-69 yfmP K transcriptional
OFKINFCL_00832 1.5e-209 yfmO EGP Major facilitator Superfamily
OFKINFCL_00833 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OFKINFCL_00834 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
OFKINFCL_00835 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
OFKINFCL_00836 2.7e-188 yfmJ S N-terminal domain of oxidoreductase
OFKINFCL_00837 2.2e-213 G Major Facilitator Superfamily
OFKINFCL_00838 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
OFKINFCL_00839 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
OFKINFCL_00840 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFKINFCL_00841 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFKINFCL_00842 6.3e-155 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
OFKINFCL_00843 5e-24 S Protein of unknown function (DUF3212)
OFKINFCL_00844 7.6e-58 yflT S Heat induced stress protein YflT
OFKINFCL_00845 2.5e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
OFKINFCL_00846 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
OFKINFCL_00847 1.4e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OFKINFCL_00848 8.9e-119 citT T response regulator
OFKINFCL_00849 3.1e-178 yflP S Tripartite tricarboxylate transporter family receptor
OFKINFCL_00850 1.9e-226 citM C Citrate transporter
OFKINFCL_00851 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
OFKINFCL_00852 1.3e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OFKINFCL_00853 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OFKINFCL_00854 6.4e-122 yflK S protein conserved in bacteria
OFKINFCL_00855 4e-18 yflJ S Protein of unknown function (DUF2639)
OFKINFCL_00856 4.1e-19 yflI
OFKINFCL_00857 2.4e-50 yflH S Protein of unknown function (DUF3243)
OFKINFCL_00858 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
OFKINFCL_00859 1.5e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
OFKINFCL_00860 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OFKINFCL_00861 6e-67 yhdN S Domain of unknown function (DUF1992)
OFKINFCL_00862 2.2e-252 agcS_1 E Sodium alanine symporter
OFKINFCL_00863 1.1e-192 E Spore germination protein
OFKINFCL_00865 5.1e-207 yfkR S spore germination
OFKINFCL_00866 1.5e-283 yfkQ EG Spore germination protein
OFKINFCL_00867 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFKINFCL_00868 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OFKINFCL_00869 1.8e-133 treR K transcriptional
OFKINFCL_00870 1.6e-125 yfkO C nitroreductase
OFKINFCL_00871 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
OFKINFCL_00872 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
OFKINFCL_00873 8.9e-207 ydiM EGP Major facilitator Superfamily
OFKINFCL_00874 2.1e-29 yfkK S Belongs to the UPF0435 family
OFKINFCL_00875 3e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OFKINFCL_00876 2.4e-50 yfkI S gas vesicle protein
OFKINFCL_00877 9.7e-144 yihY S Belongs to the UPF0761 family
OFKINFCL_00879 4.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
OFKINFCL_00880 2.3e-182 cax P COG0387 Ca2 H antiporter
OFKINFCL_00881 1.2e-146 yfkD S YfkD-like protein
OFKINFCL_00882 6e-149 yfkC M Mechanosensitive ion channel
OFKINFCL_00883 6e-221 yfkA S YfkB-like domain
OFKINFCL_00884 1.1e-26 yfjT
OFKINFCL_00885 4.5e-154 pdaA G deacetylase
OFKINFCL_00886 2.1e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
OFKINFCL_00887 1.7e-184 corA P Mediates influx of magnesium ions
OFKINFCL_00888 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OFKINFCL_00889 1.5e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OFKINFCL_00890 5.1e-44 S YfzA-like protein
OFKINFCL_00891 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OFKINFCL_00892 1.1e-83 yfjM S Psort location Cytoplasmic, score
OFKINFCL_00893 2.8e-27 yfjL
OFKINFCL_00894 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OFKINFCL_00895 3.8e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OFKINFCL_00896 9.3e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OFKINFCL_00897 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OFKINFCL_00898 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OFKINFCL_00899 1.2e-25 sspH S Belongs to the SspH family
OFKINFCL_00900 4e-56 yfjF S UPF0060 membrane protein
OFKINFCL_00901 4e-85 S Family of unknown function (DUF5381)
OFKINFCL_00902 1.2e-124 yfjC
OFKINFCL_00903 9.6e-172 yfjB
OFKINFCL_00904 5.7e-44 yfjA S Belongs to the WXG100 family
OFKINFCL_00905 1.4e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OFKINFCL_00906 6e-140 glvR K Helix-turn-helix domain, rpiR family
OFKINFCL_00907 5.7e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFKINFCL_00908 0.0 yobO M COG5434 Endopolygalacturonase
OFKINFCL_00909 1.6e-305 yfiB3 V ABC transporter
OFKINFCL_00910 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
OFKINFCL_00911 6.4e-64 mhqP S DoxX
OFKINFCL_00912 5.7e-163 yfiE 1.13.11.2 S glyoxalase
OFKINFCL_00914 8.9e-212 yxjM T Histidine kinase
OFKINFCL_00915 2.1e-112 KT LuxR family transcriptional regulator
OFKINFCL_00916 1.5e-169 V ABC transporter, ATP-binding protein
OFKINFCL_00917 2.3e-207 V ABC-2 family transporter protein
OFKINFCL_00918 4.9e-202 V COG0842 ABC-type multidrug transport system, permease component
OFKINFCL_00919 8.3e-99 padR K transcriptional
OFKINFCL_00920 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OFKINFCL_00921 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OFKINFCL_00922 1.6e-99 yfiT S Belongs to the metal hydrolase YfiT family
OFKINFCL_00923 6.9e-284 yfiU EGP Major facilitator Superfamily
OFKINFCL_00924 5.8e-80 yfiV K transcriptional
OFKINFCL_00925 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OFKINFCL_00926 7.9e-177 yfiY P ABC transporter substrate-binding protein
OFKINFCL_00927 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFKINFCL_00928 1.5e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFKINFCL_00929 2.1e-165 yfhB 5.3.3.17 S PhzF family
OFKINFCL_00930 1.5e-106 yfhC C nitroreductase
OFKINFCL_00931 2.1e-25 yfhD S YfhD-like protein
OFKINFCL_00933 1.6e-171 yfhF S nucleoside-diphosphate sugar epimerase
OFKINFCL_00934 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
OFKINFCL_00935 9.7e-52 yfhH S Protein of unknown function (DUF1811)
OFKINFCL_00937 1.5e-209 yfhI EGP Major facilitator Superfamily
OFKINFCL_00938 6.2e-20 sspK S reproduction
OFKINFCL_00939 1.3e-44 yfhJ S WVELL protein
OFKINFCL_00940 7.3e-89 batE T Bacterial SH3 domain homologues
OFKINFCL_00941 4.3e-50 yfhL S SdpI/YhfL protein family
OFKINFCL_00942 6.7e-172 yfhM S Alpha beta hydrolase
OFKINFCL_00943 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OFKINFCL_00944 0.0 yfhO S Bacterial membrane protein YfhO
OFKINFCL_00945 5.5e-186 yfhP S membrane-bound metal-dependent
OFKINFCL_00946 1e-209 mutY L A G-specific
OFKINFCL_00947 6.9e-36 yfhS
OFKINFCL_00948 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFKINFCL_00949 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
OFKINFCL_00950 1.5e-37 ygaB S YgaB-like protein
OFKINFCL_00951 1.3e-104 ygaC J Belongs to the UPF0374 family
OFKINFCL_00952 1.8e-301 ygaD V ABC transporter
OFKINFCL_00953 8.7e-180 ygaE S Membrane
OFKINFCL_00954 8.1e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OFKINFCL_00955 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
OFKINFCL_00956 4e-80 perR P Belongs to the Fur family
OFKINFCL_00957 2.8e-55 ygzB S UPF0295 protein
OFKINFCL_00958 4.3e-166 ygxA S Nucleotidyltransferase-like
OFKINFCL_00959 1.5e-50 S COG NOG14600 non supervised orthologous group
OFKINFCL_00964 7.8e-08
OFKINFCL_00972 2e-08
OFKINFCL_00976 2.7e-143 spo0M S COG4326 Sporulation control protein
OFKINFCL_00977 3e-27
OFKINFCL_00978 2.9e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
OFKINFCL_00979 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OFKINFCL_00980 2.2e-262 ygaK C Berberine and berberine like
OFKINFCL_00982 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OFKINFCL_00983 4.8e-137 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
OFKINFCL_00984 4e-168 ssuA M Sulfonate ABC transporter
OFKINFCL_00985 3.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OFKINFCL_00986 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
OFKINFCL_00988 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OFKINFCL_00989 4.1e-78 ygaO
OFKINFCL_00990 4.4e-29 K Transcriptional regulator
OFKINFCL_00992 7.9e-114 yhzB S B3/4 domain
OFKINFCL_00993 5.1e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OFKINFCL_00994 4.8e-176 yhbB S Putative amidase domain
OFKINFCL_00995 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OFKINFCL_00996 1.8e-108 yhbD K Protein of unknown function (DUF4004)
OFKINFCL_00997 2.7e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
OFKINFCL_00998 2.1e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
OFKINFCL_00999 0.0 prkA T Ser protein kinase
OFKINFCL_01000 2.5e-225 yhbH S Belongs to the UPF0229 family
OFKINFCL_01001 2.2e-76 yhbI K DNA-binding transcription factor activity
OFKINFCL_01002 1.2e-96 yhbJ V COG1566 Multidrug resistance efflux pump
OFKINFCL_01003 3.1e-271 yhcA EGP Major facilitator Superfamily
OFKINFCL_01004 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
OFKINFCL_01005 2.8e-37 yhcC
OFKINFCL_01006 7.8e-55
OFKINFCL_01007 6.6e-60 yhcF K Transcriptional regulator
OFKINFCL_01008 1.6e-123 yhcG V ABC transporter, ATP-binding protein
OFKINFCL_01009 2.6e-166 yhcH V ABC transporter, ATP-binding protein
OFKINFCL_01010 2.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OFKINFCL_01011 1e-30 cspB K Cold-shock protein
OFKINFCL_01012 1.3e-148 metQ M Belongs to the nlpA lipoprotein family
OFKINFCL_01013 3.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
OFKINFCL_01014 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OFKINFCL_01015 2.9e-41 yhcM
OFKINFCL_01016 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OFKINFCL_01017 4.2e-137 yhcP
OFKINFCL_01018 1.5e-99 yhcQ M Spore coat protein
OFKINFCL_01019 3.9e-36 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
OFKINFCL_01020 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
OFKINFCL_01021 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
OFKINFCL_01022 1.9e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OFKINFCL_01023 9.3e-68 yhcU S Family of unknown function (DUF5365)
OFKINFCL_01024 3.8e-67 yhcV S COG0517 FOG CBS domain
OFKINFCL_01025 5.1e-119 yhcW 5.4.2.6 S hydrolase
OFKINFCL_01026 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OFKINFCL_01027 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OFKINFCL_01028 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OFKINFCL_01029 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
OFKINFCL_01030 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OFKINFCL_01031 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OFKINFCL_01032 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
OFKINFCL_01033 1.5e-211 yhcY 2.7.13.3 T Histidine kinase
OFKINFCL_01034 2e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFKINFCL_01035 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
OFKINFCL_01036 1.2e-38 yhdB S YhdB-like protein
OFKINFCL_01037 4.8e-54 yhdC S Protein of unknown function (DUF3889)
OFKINFCL_01038 3e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OFKINFCL_01039 1e-75 nsrR K Transcriptional regulator
OFKINFCL_01040 4.3e-238 ygxB M Conserved TM helix
OFKINFCL_01041 2.1e-276 ycgB S Stage V sporulation protein R
OFKINFCL_01042 6.4e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
OFKINFCL_01043 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OFKINFCL_01044 3.8e-162 citR K Transcriptional regulator
OFKINFCL_01045 1.5e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
OFKINFCL_01046 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFKINFCL_01047 3.4e-250 yhdG E amino acid
OFKINFCL_01048 5.7e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OFKINFCL_01049 6.9e-267 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFKINFCL_01050 3.8e-75 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFKINFCL_01051 8.1e-45 yhdK S Sigma-M inhibitor protein
OFKINFCL_01052 6.6e-201 yhdL S Sigma factor regulator N-terminal
OFKINFCL_01053 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
OFKINFCL_01054 5.7e-191 yhdN C Aldo keto reductase
OFKINFCL_01055 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OFKINFCL_01056 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OFKINFCL_01057 4.1e-74 cueR K transcriptional
OFKINFCL_01058 5.7e-222 yhdR 2.6.1.1 E Aminotransferase
OFKINFCL_01059 4.9e-241 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
OFKINFCL_01060 1.2e-42 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OFKINFCL_01061 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OFKINFCL_01062 1.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OFKINFCL_01064 5.6e-203 yhdY M Mechanosensitive ion channel
OFKINFCL_01065 7.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
OFKINFCL_01066 1.7e-151 yheN G deacetylase
OFKINFCL_01067 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
OFKINFCL_01068 3.5e-231 nhaC C Na H antiporter
OFKINFCL_01069 3.4e-84 nhaX T Belongs to the universal stress protein A family
OFKINFCL_01070 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
OFKINFCL_01071 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
OFKINFCL_01072 3.1e-110 yheG GM NAD(P)H-binding
OFKINFCL_01073 6.3e-28 sspB S spore protein
OFKINFCL_01074 1.3e-36 yheE S Family of unknown function (DUF5342)
OFKINFCL_01075 6.3e-265 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
OFKINFCL_01076 6.2e-215 yheC HJ YheC/D like ATP-grasp
OFKINFCL_01077 5.3e-201 yheB S Belongs to the UPF0754 family
OFKINFCL_01078 9.5e-48 yheA S Belongs to the UPF0342 family
OFKINFCL_01079 5.8e-205 yhaZ L DNA alkylation repair enzyme
OFKINFCL_01080 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
OFKINFCL_01081 1.8e-292 hemZ H coproporphyrinogen III oxidase
OFKINFCL_01082 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
OFKINFCL_01083 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
OFKINFCL_01085 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
OFKINFCL_01086 1.1e-26 S YhzD-like protein
OFKINFCL_01087 2e-166 yhaQ S ABC transporter, ATP-binding protein
OFKINFCL_01088 9.4e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
OFKINFCL_01089 1.4e-223 yhaO L DNA repair exonuclease
OFKINFCL_01090 0.0 yhaN L AAA domain
OFKINFCL_01091 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
OFKINFCL_01092 1.6e-21 yhaL S Sporulation protein YhaL
OFKINFCL_01093 2e-115 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OFKINFCL_01094 8.7e-90 yhaK S Putative zincin peptidase
OFKINFCL_01095 2.2e-54 yhaI S Protein of unknown function (DUF1878)
OFKINFCL_01096 1e-113 hpr K Negative regulator of protease production and sporulation
OFKINFCL_01097 7e-39 yhaH S YtxH-like protein
OFKINFCL_01098 5.4e-21
OFKINFCL_01099 3.6e-80 trpP S Tryptophan transporter TrpP
OFKINFCL_01100 7.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OFKINFCL_01101 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
OFKINFCL_01102 4.6e-137 ecsA V transporter (ATP-binding protein)
OFKINFCL_01103 1.1e-212 ecsB U ABC transporter
OFKINFCL_01104 6.9e-114 ecsC S EcsC protein family
OFKINFCL_01105 8.3e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OFKINFCL_01106 2.8e-244 yhfA C membrane
OFKINFCL_01107 7.5e-17 1.15.1.2 C Rubrerythrin
OFKINFCL_01108 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
OFKINFCL_01109 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OFKINFCL_01110 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OFKINFCL_01111 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
OFKINFCL_01112 4.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OFKINFCL_01113 5.4e-101 yhgD K Transcriptional regulator
OFKINFCL_01114 1e-238 yhgE S YhgE Pip N-terminal domain protein
OFKINFCL_01115 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OFKINFCL_01116 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
OFKINFCL_01117 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
OFKINFCL_01118 3.7e-72 3.4.13.21 S ASCH
OFKINFCL_01119 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OFKINFCL_01120 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
OFKINFCL_01121 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
OFKINFCL_01122 5e-111 yhfK GM NmrA-like family
OFKINFCL_01123 2.4e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OFKINFCL_01124 1.9e-65 yhfM
OFKINFCL_01125 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
OFKINFCL_01126 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
OFKINFCL_01127 1.7e-78 VY92_01935 K acetyltransferase
OFKINFCL_01128 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
OFKINFCL_01129 4.3e-159 yfmC M Periplasmic binding protein
OFKINFCL_01130 1.2e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
OFKINFCL_01131 3.2e-195 vraB 2.3.1.9 I Belongs to the thiolase family
OFKINFCL_01132 1.8e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OFKINFCL_01133 1.1e-90 bioY S BioY family
OFKINFCL_01134 1.7e-182 hemAT NT chemotaxis protein
OFKINFCL_01135 5.2e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
OFKINFCL_01136 6.1e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFKINFCL_01137 1.3e-32 yhzC S IDEAL
OFKINFCL_01138 9.3e-109 comK K Competence transcription factor
OFKINFCL_01139 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
OFKINFCL_01140 7e-37 yhjA S Excalibur calcium-binding domain
OFKINFCL_01141 5.7e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OFKINFCL_01142 6.9e-27 yhjC S Protein of unknown function (DUF3311)
OFKINFCL_01143 6.7e-60 yhjD
OFKINFCL_01144 1e-108 yhjE S SNARE associated Golgi protein
OFKINFCL_01145 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
OFKINFCL_01146 1.3e-282 yhjG CH FAD binding domain
OFKINFCL_01147 1.7e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
OFKINFCL_01148 5.8e-214 glcP G Major Facilitator Superfamily
OFKINFCL_01149 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
OFKINFCL_01150 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
OFKINFCL_01151 6.3e-254 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
OFKINFCL_01152 5.9e-188 yhjM 5.1.1.1 K Transcriptional regulator
OFKINFCL_01153 4.2e-201 abrB S membrane
OFKINFCL_01154 4.6e-211 EGP Transmembrane secretion effector
OFKINFCL_01155 0.0 S Sugar transport-related sRNA regulator N-term
OFKINFCL_01156 1.6e-36 yhjQ C COG1145 Ferredoxin
OFKINFCL_01157 2.2e-78 yhjR S Rubrerythrin
OFKINFCL_01158 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
OFKINFCL_01159 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OFKINFCL_01160 2e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
OFKINFCL_01161 0.0 sbcC L COG0419 ATPase involved in DNA repair
OFKINFCL_01162 1.1e-49 yisB V COG1403 Restriction endonuclease
OFKINFCL_01163 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
OFKINFCL_01164 3e-66 gerPE S Spore germination protein GerPE
OFKINFCL_01165 6.3e-24 gerPD S Spore germination protein
OFKINFCL_01166 5.3e-54 gerPC S Spore germination protein
OFKINFCL_01167 4e-34 gerPB S cell differentiation
OFKINFCL_01168 1.9e-33 gerPA S Spore germination protein
OFKINFCL_01169 1.5e-22 yisI S Spo0E like sporulation regulatory protein
OFKINFCL_01170 5.9e-174 cotH M Spore Coat
OFKINFCL_01171 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OFKINFCL_01172 3e-57 yisL S UPF0344 protein
OFKINFCL_01173 0.0 wprA O Belongs to the peptidase S8 family
OFKINFCL_01174 5.8e-100 yisN S Protein of unknown function (DUF2777)
OFKINFCL_01175 0.0 asnO 6.3.5.4 E Asparagine synthase
OFKINFCL_01176 4.7e-88 yizA S Damage-inducible protein DinB
OFKINFCL_01177 9.8e-149 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
OFKINFCL_01178 4e-243 yisQ V Mate efflux family protein
OFKINFCL_01179 1.2e-160 yisR K Transcriptional regulator
OFKINFCL_01180 4.5e-183 purR K helix_turn _helix lactose operon repressor
OFKINFCL_01182 1.5e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
OFKINFCL_01183 7e-92 yisT S DinB family
OFKINFCL_01184 7.2e-89 argO S Lysine exporter protein LysE YggA
OFKINFCL_01185 3.8e-276 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFKINFCL_01186 2e-35 mcbG S Pentapeptide repeats (9 copies)
OFKINFCL_01187 9.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OFKINFCL_01188 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
OFKINFCL_01189 2.7e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OFKINFCL_01190 2.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OFKINFCL_01191 3e-122 comB 3.1.3.71 H Belongs to the ComB family
OFKINFCL_01192 1e-139 yitD 4.4.1.19 S synthase
OFKINFCL_01193 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OFKINFCL_01194 4e-217 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OFKINFCL_01195 2.8e-227 yitG EGP Major facilitator Superfamily
OFKINFCL_01196 7.9e-149 yitH K Acetyltransferase (GNAT) domain
OFKINFCL_01197 1.2e-71 yjcF S Acetyltransferase (GNAT) domain
OFKINFCL_01198 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
OFKINFCL_01199 4.3e-54 yajQ S Belongs to the UPF0234 family
OFKINFCL_01200 6.9e-161 cvfB S protein conserved in bacteria
OFKINFCL_01201 8.5e-94
OFKINFCL_01202 6.8e-170
OFKINFCL_01203 1.5e-97 S Sporulation delaying protein SdpA
OFKINFCL_01204 1.5e-58 K Transcriptional regulator PadR-like family
OFKINFCL_01205 2.9e-94
OFKINFCL_01206 1.4e-44 yitR S Domain of unknown function (DUF3784)
OFKINFCL_01207 6.7e-311 nprB 3.4.24.28 E Peptidase M4
OFKINFCL_01208 1.6e-157 yitS S protein conserved in bacteria
OFKINFCL_01209 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
OFKINFCL_01210 5e-73 ipi S Intracellular proteinase inhibitor
OFKINFCL_01211 2.8e-17 S Protein of unknown function (DUF3813)
OFKINFCL_01213 2.1e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
OFKINFCL_01214 3.8e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
OFKINFCL_01215 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
OFKINFCL_01216 1.5e-22 pilT S Proteolipid membrane potential modulator
OFKINFCL_01217 3.2e-267 yitY C D-arabinono-1,4-lactone oxidase
OFKINFCL_01218 3.8e-88 norB G Major Facilitator Superfamily
OFKINFCL_01219 5.6e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OFKINFCL_01220 2.6e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OFKINFCL_01221 2.7e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
OFKINFCL_01222 1.3e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
OFKINFCL_01223 1.1e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OFKINFCL_01224 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
OFKINFCL_01225 1.9e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OFKINFCL_01226 9.5e-28 yjzC S YjzC-like protein
OFKINFCL_01227 2.3e-16 yjzD S Protein of unknown function (DUF2929)
OFKINFCL_01228 6.2e-142 yjaU I carboxylic ester hydrolase activity
OFKINFCL_01229 1.8e-101 yjaV
OFKINFCL_01230 2.5e-183 med S Transcriptional activator protein med
OFKINFCL_01231 7.3e-26 comZ S ComZ
OFKINFCL_01232 2.7e-22 yjzB
OFKINFCL_01233 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OFKINFCL_01234 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OFKINFCL_01235 1.1e-149 yjaZ O Zn-dependent protease
OFKINFCL_01236 1.8e-184 appD P Belongs to the ABC transporter superfamily
OFKINFCL_01237 4.2e-186 appF E Belongs to the ABC transporter superfamily
OFKINFCL_01238 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
OFKINFCL_01239 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFKINFCL_01240 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFKINFCL_01241 1.5e-146 yjbA S Belongs to the UPF0736 family
OFKINFCL_01242 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
OFKINFCL_01243 0.0 oppA E ABC transporter substrate-binding protein
OFKINFCL_01244 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFKINFCL_01245 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFKINFCL_01246 1.5e-197 oppD P Belongs to the ABC transporter superfamily
OFKINFCL_01247 5.5e-172 oppF E Belongs to the ABC transporter superfamily
OFKINFCL_01248 4.9e-205 yjbB EGP Major Facilitator Superfamily
OFKINFCL_01249 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFKINFCL_01250 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OFKINFCL_01251 6e-112 yjbE P Integral membrane protein TerC family
OFKINFCL_01252 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OFKINFCL_01253 1.8e-220 yjbF S Competence protein
OFKINFCL_01254 0.0 pepF E oligoendopeptidase F
OFKINFCL_01255 1.8e-20
OFKINFCL_01257 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OFKINFCL_01258 3.7e-72 yjbI S Bacterial-like globin
OFKINFCL_01259 5.3e-85 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OFKINFCL_01260 2.4e-101 yjbK S protein conserved in bacteria
OFKINFCL_01261 7.1e-62 yjbL S Belongs to the UPF0738 family
OFKINFCL_01262 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
OFKINFCL_01263 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OFKINFCL_01264 4e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OFKINFCL_01265 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
OFKINFCL_01266 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OFKINFCL_01267 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OFKINFCL_01268 4.2e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
OFKINFCL_01269 1.3e-215 thiO 1.4.3.19 E Glycine oxidase
OFKINFCL_01270 6.7e-30 thiS H thiamine diphosphate biosynthetic process
OFKINFCL_01271 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
OFKINFCL_01272 2.3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OFKINFCL_01273 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OFKINFCL_01274 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
OFKINFCL_01275 6.5e-53 yjbX S Spore coat protein
OFKINFCL_01276 4.4e-82 cotZ S Spore coat protein
OFKINFCL_01277 7.6e-96 cotY S Spore coat protein Z
OFKINFCL_01278 1.2e-67 cotX S Spore Coat Protein X and V domain
OFKINFCL_01279 7.4e-23 cotW
OFKINFCL_01280 3.2e-49 cotV S Spore Coat Protein X and V domain
OFKINFCL_01281 1.9e-56 yjcA S Protein of unknown function (DUF1360)
OFKINFCL_01284 2.9e-38 spoVIF S Stage VI sporulation protein F
OFKINFCL_01285 0.0 yjcD 3.6.4.12 L DNA helicase
OFKINFCL_01286 1.7e-38
OFKINFCL_01287 1.5e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFKINFCL_01288 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
OFKINFCL_01289 2.2e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
OFKINFCL_01290 9.5e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OFKINFCL_01291 1.9e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OFKINFCL_01292 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
OFKINFCL_01293 3e-210 yjcL S Protein of unknown function (DUF819)
OFKINFCL_01295 1.8e-12
OFKINFCL_01296 8.7e-31
OFKINFCL_01297 1.1e-243 M nucleic acid phosphodiester bond hydrolysis
OFKINFCL_01298 8.3e-21
OFKINFCL_01301 1.2e-128 S response regulator aspartate phosphatase
OFKINFCL_01302 5.4e-46 yjcS S Antibiotic biosynthesis monooxygenase
OFKINFCL_01303 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
OFKINFCL_01305 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
OFKINFCL_01306 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
OFKINFCL_01307 1.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
OFKINFCL_01308 4.1e-50 yjdF S Protein of unknown function (DUF2992)
OFKINFCL_01309 2.2e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
OFKINFCL_01311 1.2e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OFKINFCL_01312 1.6e-28 S Domain of unknown function (DUF4177)
OFKINFCL_01313 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
OFKINFCL_01314 1.6e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OFKINFCL_01316 1.4e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
OFKINFCL_01317 1.4e-81 S Protein of unknown function (DUF2690)
OFKINFCL_01318 8.9e-20 yjfB S Putative motility protein
OFKINFCL_01319 2.1e-168 yjfC O Predicted Zn-dependent protease (DUF2268)
OFKINFCL_01320 2.7e-45 T PhoQ Sensor
OFKINFCL_01321 2e-103 yjgB S Domain of unknown function (DUF4309)
OFKINFCL_01322 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
OFKINFCL_01323 1.6e-94 yjgD S Protein of unknown function (DUF1641)
OFKINFCL_01324 8.7e-07 S Domain of unknown function (DUF4352)
OFKINFCL_01325 6e-114 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
OFKINFCL_01327 6.9e-33 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
OFKINFCL_01328 2.7e-174 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
OFKINFCL_01329 1e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OFKINFCL_01330 8.2e-30
OFKINFCL_01331 3.6e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OFKINFCL_01332 1.9e-122 ybbM S transport system, permease component
OFKINFCL_01333 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
OFKINFCL_01334 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
OFKINFCL_01335 9.8e-91 yjlB S Cupin domain
OFKINFCL_01336 7.1e-66 yjlC S Protein of unknown function (DUF1641)
OFKINFCL_01337 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
OFKINFCL_01338 1e-278 uxaC 5.3.1.12 G glucuronate isomerase
OFKINFCL_01339 8.3e-249 yjmB G symporter YjmB
OFKINFCL_01340 8.1e-193 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
OFKINFCL_01341 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
OFKINFCL_01342 1.5e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
OFKINFCL_01343 2.6e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OFKINFCL_01344 3.2e-223 exuT G Sugar (and other) transporter
OFKINFCL_01345 6.8e-184 exuR K transcriptional
OFKINFCL_01346 2.3e-281 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
OFKINFCL_01347 1e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
OFKINFCL_01348 4.3e-130 MA20_18170 S membrane transporter protein
OFKINFCL_01349 2.3e-78 yjoA S DinB family
OFKINFCL_01350 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
OFKINFCL_01351 1e-212 S response regulator aspartate phosphatase
OFKINFCL_01353 5.3e-40 S YCII-related domain
OFKINFCL_01354 1.6e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
OFKINFCL_01355 6.1e-61 yjqA S Bacterial PH domain
OFKINFCL_01356 7.9e-111 yjqB S Pfam:DUF867
OFKINFCL_01357 4.4e-160 ydbD P Catalase
OFKINFCL_01358 1e-110 xkdA E IrrE N-terminal-like domain
OFKINFCL_01359 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
OFKINFCL_01361 5.9e-157 xkdB K sequence-specific DNA binding
OFKINFCL_01362 4.1e-118 xkdC L Bacterial dnaA protein
OFKINFCL_01365 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
OFKINFCL_01366 1.8e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OFKINFCL_01367 4.5e-138 xtmA L phage terminase small subunit
OFKINFCL_01368 8.1e-254 xtmB S phage terminase, large subunit
OFKINFCL_01369 1.7e-284 yqbA S portal protein
OFKINFCL_01370 7.7e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
OFKINFCL_01371 5.8e-169 xkdG S Phage capsid family
OFKINFCL_01372 5.6e-62 yqbG S Protein of unknown function (DUF3199)
OFKINFCL_01373 8.7e-65 yqbH S Domain of unknown function (DUF3599)
OFKINFCL_01374 9.9e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
OFKINFCL_01375 1.9e-77 xkdJ
OFKINFCL_01376 2.5e-256 xkdK S Phage tail sheath C-terminal domain
OFKINFCL_01377 6.1e-76 xkdM S Phage tail tube protein
OFKINFCL_01378 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
OFKINFCL_01379 0.0 xkdO L Transglycosylase SLT domain
OFKINFCL_01380 3.7e-122 xkdP S Lysin motif
OFKINFCL_01381 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
OFKINFCL_01382 2.1e-39 xkdR S Protein of unknown function (DUF2577)
OFKINFCL_01383 9.6e-71 xkdS S Protein of unknown function (DUF2634)
OFKINFCL_01384 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OFKINFCL_01385 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
OFKINFCL_01386 6.7e-41
OFKINFCL_01387 3.5e-190
OFKINFCL_01388 1e-51 xkdW S XkdW protein
OFKINFCL_01389 1.2e-21 xkdX
OFKINFCL_01390 8.3e-151 xepA
OFKINFCL_01391 6.2e-39 xhlA S Haemolysin XhlA
OFKINFCL_01392 9.3e-40 xhlB S SPP1 phage holin
OFKINFCL_01393 1.8e-159 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OFKINFCL_01394 1e-63 G Acyltransferase family
OFKINFCL_01396 6.7e-23 spoIISB S Stage II sporulation protein SB
OFKINFCL_01397 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
OFKINFCL_01398 5.8e-175 pit P phosphate transporter
OFKINFCL_01399 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
OFKINFCL_01400 5.2e-240 steT E amino acid
OFKINFCL_01401 2.1e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
OFKINFCL_01403 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OFKINFCL_01404 1.9e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OFKINFCL_01406 2e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OFKINFCL_01407 1.2e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
OFKINFCL_01408 3.3e-152 dppA E D-aminopeptidase
OFKINFCL_01409 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFKINFCL_01410 8.1e-174 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFKINFCL_01411 1.9e-186 dppD P Belongs to the ABC transporter superfamily
OFKINFCL_01412 0.0 dppE E ABC transporter substrate-binding protein
OFKINFCL_01414 7.6e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
OFKINFCL_01415 5.2e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OFKINFCL_01416 4.1e-164 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OFKINFCL_01417 5e-187 ykfD E Belongs to the ABC transporter superfamily
OFKINFCL_01418 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
OFKINFCL_01419 1.2e-160 ykgA E Amidinotransferase
OFKINFCL_01420 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
OFKINFCL_01421 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OFKINFCL_01422 7.2e-09
OFKINFCL_01423 2.7e-129 ykjA S Protein of unknown function (DUF421)
OFKINFCL_01424 2e-97 ykkA S Protein of unknown function (DUF664)
OFKINFCL_01425 1.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OFKINFCL_01426 3.5e-55 ykkC P Multidrug resistance protein
OFKINFCL_01427 7e-50 ykkD P Multidrug resistance protein
OFKINFCL_01428 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
OFKINFCL_01429 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OFKINFCL_01430 1.1e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OFKINFCL_01431 1.3e-70 ohrA O Organic hydroperoxide resistance protein
OFKINFCL_01432 2.2e-73 ohrR K COG1846 Transcriptional regulators
OFKINFCL_01433 8.4e-72 ohrB O Organic hydroperoxide resistance protein
OFKINFCL_01435 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
OFKINFCL_01436 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OFKINFCL_01437 5e-176 isp O Belongs to the peptidase S8 family
OFKINFCL_01438 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OFKINFCL_01439 4.5e-135 ykoC P Cobalt transport protein
OFKINFCL_01440 1.2e-307 P ABC transporter, ATP-binding protein
OFKINFCL_01441 3.3e-77 ykoE S ABC-type cobalt transport system, permease component
OFKINFCL_01442 1.8e-110 ykoF S YKOF-related Family
OFKINFCL_01443 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFKINFCL_01444 8.3e-241 ykoH 2.7.13.3 T Histidine kinase
OFKINFCL_01445 2.1e-112 ykoI S Peptidase propeptide and YPEB domain
OFKINFCL_01446 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
OFKINFCL_01449 2.2e-222 mgtE P Acts as a magnesium transporter
OFKINFCL_01450 1.4e-53 tnrA K transcriptional
OFKINFCL_01451 5.9e-18
OFKINFCL_01452 6.9e-26 ykoL
OFKINFCL_01453 1.3e-81 mhqR K transcriptional
OFKINFCL_01454 1e-212 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
OFKINFCL_01455 1.1e-98 ykoP G polysaccharide deacetylase
OFKINFCL_01456 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
OFKINFCL_01457 0.0 ykoS
OFKINFCL_01458 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OFKINFCL_01459 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
OFKINFCL_01460 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OFKINFCL_01461 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
OFKINFCL_01462 7.8e-109 ykoX S membrane-associated protein
OFKINFCL_01463 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
OFKINFCL_01464 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFKINFCL_01465 1.7e-114 rsgI S Anti-sigma factor N-terminus
OFKINFCL_01466 1.9e-26 sspD S small acid-soluble spore protein
OFKINFCL_01467 1.9e-124 ykrK S Domain of unknown function (DUF1836)
OFKINFCL_01468 3.5e-155 htpX O Belongs to the peptidase M48B family
OFKINFCL_01469 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
OFKINFCL_01470 1.2e-10 ydfR S Protein of unknown function (DUF421)
OFKINFCL_01471 4.1e-18 ykzE
OFKINFCL_01472 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
OFKINFCL_01473 0.0 kinE 2.7.13.3 T Histidine kinase
OFKINFCL_01474 1.6e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OFKINFCL_01476 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OFKINFCL_01477 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OFKINFCL_01478 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OFKINFCL_01479 1.1e-231 mtnE 2.6.1.83 E Aminotransferase
OFKINFCL_01480 2.9e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
OFKINFCL_01481 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OFKINFCL_01482 2.7e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
OFKINFCL_01483 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OFKINFCL_01484 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
OFKINFCL_01485 7.5e-10 S Spo0E like sporulation regulatory protein
OFKINFCL_01486 2e-63 eag
OFKINFCL_01487 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
OFKINFCL_01488 1.3e-75 ykvE K transcriptional
OFKINFCL_01489 2.5e-125 motB N Flagellar motor protein
OFKINFCL_01490 1e-137 motA N flagellar motor
OFKINFCL_01491 0.0 clpE O Belongs to the ClpA ClpB family
OFKINFCL_01492 1.8e-179 ykvI S membrane
OFKINFCL_01493 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OFKINFCL_01494 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
OFKINFCL_01495 6.4e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
OFKINFCL_01496 7.8e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OFKINFCL_01497 2e-61 ykvN K Transcriptional regulator
OFKINFCL_01498 1.6e-132 IQ Enoyl-(Acyl carrier protein) reductase
OFKINFCL_01499 9.9e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
OFKINFCL_01500 1e-29 3.5.1.104 M LysM domain
OFKINFCL_01501 6.9e-162 G Glycosyl hydrolases family 18
OFKINFCL_01502 1.4e-44 ykvR S Protein of unknown function (DUF3219)
OFKINFCL_01503 6e-25 ykvS S protein conserved in bacteria
OFKINFCL_01504 2.8e-28
OFKINFCL_01505 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
OFKINFCL_01506 4.2e-237 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OFKINFCL_01507 4.9e-90 stoA CO thiol-disulfide
OFKINFCL_01508 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OFKINFCL_01509 2.3e-09
OFKINFCL_01510 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OFKINFCL_01511 5.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
OFKINFCL_01512 7.6e-128 glcT K antiterminator
OFKINFCL_01513 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFKINFCL_01514 2.1e-39 ptsH G phosphocarrier protein HPr
OFKINFCL_01515 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OFKINFCL_01516 7.2e-39 splA S Transcriptional regulator
OFKINFCL_01517 1.7e-201 splB 4.1.99.14 L Spore photoproduct lyase
OFKINFCL_01518 8.3e-128 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFKINFCL_01519 2.9e-263 mcpC NT chemotaxis protein
OFKINFCL_01520 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OFKINFCL_01521 7e-120 ykwD J protein with SCP PR1 domains
OFKINFCL_01522 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
OFKINFCL_01523 0.0 pilS 2.7.13.3 T Histidine kinase
OFKINFCL_01524 5.7e-222 patA 2.6.1.1 E Aminotransferase
OFKINFCL_01525 2.2e-15
OFKINFCL_01526 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
OFKINFCL_01527 1.7e-84 ykyB S YkyB-like protein
OFKINFCL_01528 2.8e-238 ykuC EGP Major facilitator Superfamily
OFKINFCL_01529 1.8e-87 ykuD S protein conserved in bacteria
OFKINFCL_01530 2.1e-165 ykuE S Metallophosphoesterase
OFKINFCL_01531 4.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFKINFCL_01532 5.2e-234 ykuI T Diguanylate phosphodiesterase
OFKINFCL_01533 3.9e-37 ykuJ S protein conserved in bacteria
OFKINFCL_01534 4.4e-94 ykuK S Ribonuclease H-like
OFKINFCL_01535 3.9e-27 ykzF S Antirepressor AbbA
OFKINFCL_01536 1.6e-76 ykuL S CBS domain
OFKINFCL_01537 3.5e-168 ccpC K Transcriptional regulator
OFKINFCL_01538 2.4e-86 fld C Flavodoxin domain
OFKINFCL_01539 6.1e-176 ykuO
OFKINFCL_01540 4.6e-79 fld C Flavodoxin
OFKINFCL_01541 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OFKINFCL_01542 4.9e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OFKINFCL_01543 2e-36 ykuS S Belongs to the UPF0180 family
OFKINFCL_01544 8.8e-142 ykuT M Mechanosensitive ion channel
OFKINFCL_01545 3.9e-101 ykuU O Alkyl hydroperoxide reductase
OFKINFCL_01546 4.4e-82 ykuV CO thiol-disulfide
OFKINFCL_01547 5.8e-95 rok K Repressor of ComK
OFKINFCL_01548 2.9e-147 yknT
OFKINFCL_01549 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
OFKINFCL_01550 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OFKINFCL_01551 1.5e-244 moeA 2.10.1.1 H molybdopterin
OFKINFCL_01552 6.4e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
OFKINFCL_01553 7.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
OFKINFCL_01554 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OFKINFCL_01555 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
OFKINFCL_01556 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
OFKINFCL_01557 2.9e-117 yknW S Yip1 domain
OFKINFCL_01558 4.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OFKINFCL_01559 2.5e-124 macB V ABC transporter, ATP-binding protein
OFKINFCL_01560 2.8e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
OFKINFCL_01561 5.2e-136 fruR K Transcriptional regulator
OFKINFCL_01562 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
OFKINFCL_01563 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
OFKINFCL_01564 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OFKINFCL_01565 8.1e-39 ykoA
OFKINFCL_01566 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OFKINFCL_01567 1.1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OFKINFCL_01568 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
OFKINFCL_01569 1.1e-12 S Uncharacterized protein YkpC
OFKINFCL_01570 7.7e-183 mreB D Rod-share determining protein MreBH
OFKINFCL_01571 1.5e-43 abrB K of stationary sporulation gene expression
OFKINFCL_01572 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
OFKINFCL_01573 6.5e-156 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
OFKINFCL_01574 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
OFKINFCL_01575 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OFKINFCL_01576 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OFKINFCL_01577 8.2e-31 ykzG S Belongs to the UPF0356 family
OFKINFCL_01578 1e-145 ykrA S hydrolases of the HAD superfamily
OFKINFCL_01579 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OFKINFCL_01581 4.6e-109 recN L Putative cell-wall binding lipoprotein
OFKINFCL_01582 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OFKINFCL_01583 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OFKINFCL_01584 2.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OFKINFCL_01585 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OFKINFCL_01586 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
OFKINFCL_01587 3.5e-277 speA 4.1.1.19 E Arginine
OFKINFCL_01588 1.6e-42 yktA S Belongs to the UPF0223 family
OFKINFCL_01589 2.1e-117 yktB S Belongs to the UPF0637 family
OFKINFCL_01590 7.1e-26 ykzI
OFKINFCL_01591 4.3e-149 suhB 3.1.3.25 G Inositol monophosphatase
OFKINFCL_01592 6.9e-78 ykzC S Acetyltransferase (GNAT) family
OFKINFCL_01593 9.3e-172 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OFKINFCL_01594 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
OFKINFCL_01595 0.0 ylaA
OFKINFCL_01596 2.7e-42 ylaB
OFKINFCL_01597 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
OFKINFCL_01598 7.1e-12 sigC S Putative zinc-finger
OFKINFCL_01599 4.1e-38 ylaE
OFKINFCL_01600 8.2e-22 S Family of unknown function (DUF5325)
OFKINFCL_01601 0.0 typA T GTP-binding protein TypA
OFKINFCL_01602 4.2e-47 ylaH S YlaH-like protein
OFKINFCL_01603 2.5e-32 ylaI S protein conserved in bacteria
OFKINFCL_01604 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OFKINFCL_01605 6.8e-248 phoH T ATPase related to phosphate starvation-inducible protein PhoH
OFKINFCL_01606 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OFKINFCL_01607 1.2e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
OFKINFCL_01608 8.7e-44 ylaN S Belongs to the UPF0358 family
OFKINFCL_01609 4.5e-214 ftsW D Belongs to the SEDS family
OFKINFCL_01610 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OFKINFCL_01611 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
OFKINFCL_01612 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OFKINFCL_01613 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
OFKINFCL_01614 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OFKINFCL_01615 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
OFKINFCL_01616 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
OFKINFCL_01617 1.5e-166 ctaG S cytochrome c oxidase
OFKINFCL_01618 7e-62 ylbA S YugN-like family
OFKINFCL_01619 2.6e-74 ylbB T COG0517 FOG CBS domain
OFKINFCL_01620 9.6e-200 ylbC S protein with SCP PR1 domains
OFKINFCL_01621 4.1e-63 ylbD S Putative coat protein
OFKINFCL_01622 6.7e-37 ylbE S YlbE-like protein
OFKINFCL_01623 1.8e-75 ylbF S Belongs to the UPF0342 family
OFKINFCL_01624 3.7e-38 ylbG S UPF0298 protein
OFKINFCL_01625 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
OFKINFCL_01626 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OFKINFCL_01627 2.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
OFKINFCL_01628 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
OFKINFCL_01629 2.6e-186 ylbL T Belongs to the peptidase S16 family
OFKINFCL_01630 1.1e-228 ylbM S Belongs to the UPF0348 family
OFKINFCL_01632 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
OFKINFCL_01633 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OFKINFCL_01634 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
OFKINFCL_01635 1.5e-88 ylbP K n-acetyltransferase
OFKINFCL_01636 1.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OFKINFCL_01637 1.2e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OFKINFCL_01638 2.9e-78 mraZ K Belongs to the MraZ family
OFKINFCL_01639 1.8e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OFKINFCL_01640 3.7e-44 ftsL D Essential cell division protein
OFKINFCL_01641 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OFKINFCL_01642 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
OFKINFCL_01643 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OFKINFCL_01644 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OFKINFCL_01645 2.9e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OFKINFCL_01646 5.7e-186 spoVE D Belongs to the SEDS family
OFKINFCL_01647 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OFKINFCL_01648 5.3e-167 murB 1.3.1.98 M cell wall formation
OFKINFCL_01649 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OFKINFCL_01650 2.4e-103 ylxW S protein conserved in bacteria
OFKINFCL_01651 4.3e-93 ylxX S protein conserved in bacteria
OFKINFCL_01652 6.2e-58 sbp S small basic protein
OFKINFCL_01653 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OFKINFCL_01654 6.2e-173 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OFKINFCL_01655 2.3e-264 Q Non-ribosomal peptide synthetase modules and related proteins
OFKINFCL_01656 3.6e-42 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OFKINFCL_01657 0.0 bpr O COG1404 Subtilisin-like serine proteases
OFKINFCL_01658 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
OFKINFCL_01659 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFKINFCL_01660 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFKINFCL_01661 2.6e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
OFKINFCL_01662 2.3e-253 argE 3.5.1.16 E Acetylornithine deacetylase
OFKINFCL_01663 2.4e-37 ylmC S sporulation protein
OFKINFCL_01664 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
OFKINFCL_01665 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OFKINFCL_01666 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OFKINFCL_01667 1.6e-39 yggT S membrane
OFKINFCL_01668 7.5e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
OFKINFCL_01669 2.6e-67 divIVA D Cell division initiation protein
OFKINFCL_01670 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OFKINFCL_01671 1.3e-63 dksA T COG1734 DnaK suppressor protein
OFKINFCL_01672 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OFKINFCL_01673 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OFKINFCL_01674 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OFKINFCL_01675 4.5e-231 pyrP F Xanthine uracil
OFKINFCL_01676 5.9e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OFKINFCL_01677 9.2e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OFKINFCL_01678 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OFKINFCL_01679 0.0 carB 6.3.5.5 F Belongs to the CarB family
OFKINFCL_01680 1.4e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
OFKINFCL_01681 1.4e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OFKINFCL_01682 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OFKINFCL_01683 1e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OFKINFCL_01684 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OFKINFCL_01685 1.4e-179 cysP P phosphate transporter
OFKINFCL_01686 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OFKINFCL_01687 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
OFKINFCL_01688 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OFKINFCL_01689 5.8e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
OFKINFCL_01690 1.4e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
OFKINFCL_01691 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
OFKINFCL_01692 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
OFKINFCL_01693 3.1e-156 yloC S stress-induced protein
OFKINFCL_01694 1.5e-40 ylzA S Belongs to the UPF0296 family
OFKINFCL_01695 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
OFKINFCL_01696 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OFKINFCL_01697 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OFKINFCL_01698 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OFKINFCL_01699 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OFKINFCL_01700 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OFKINFCL_01701 4.2e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OFKINFCL_01702 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
OFKINFCL_01703 1.6e-140 stp 3.1.3.16 T phosphatase
OFKINFCL_01704 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
OFKINFCL_01705 4.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OFKINFCL_01706 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OFKINFCL_01707 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
OFKINFCL_01708 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OFKINFCL_01709 5.5e-59 asp S protein conserved in bacteria
OFKINFCL_01710 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
OFKINFCL_01711 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
OFKINFCL_01712 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
OFKINFCL_01713 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OFKINFCL_01714 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
OFKINFCL_01715 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OFKINFCL_01716 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OFKINFCL_01717 6.1e-129 IQ reductase
OFKINFCL_01718 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OFKINFCL_01719 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OFKINFCL_01720 0.0 smc D Required for chromosome condensation and partitioning
OFKINFCL_01721 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OFKINFCL_01722 2.9e-87
OFKINFCL_01723 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OFKINFCL_01724 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OFKINFCL_01725 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OFKINFCL_01726 4.5e-36 ylqC S Belongs to the UPF0109 family
OFKINFCL_01727 1.4e-60 ylqD S YlqD protein
OFKINFCL_01728 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OFKINFCL_01729 2.1e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OFKINFCL_01730 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OFKINFCL_01731 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OFKINFCL_01732 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OFKINFCL_01733 8.5e-291 ylqG
OFKINFCL_01734 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
OFKINFCL_01735 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
OFKINFCL_01736 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OFKINFCL_01737 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
OFKINFCL_01738 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OFKINFCL_01739 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OFKINFCL_01740 2.5e-169 xerC L tyrosine recombinase XerC
OFKINFCL_01741 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OFKINFCL_01742 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OFKINFCL_01743 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OFKINFCL_01744 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
OFKINFCL_01745 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
OFKINFCL_01746 1.9e-31 fliE N Flagellar hook-basal body
OFKINFCL_01747 2.6e-254 fliF N The M ring may be actively involved in energy transduction
OFKINFCL_01748 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OFKINFCL_01749 1.3e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
OFKINFCL_01750 9.4e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
OFKINFCL_01751 3.2e-69 fliJ N Flagellar biosynthesis chaperone
OFKINFCL_01752 7.7e-37 ylxF S MgtE intracellular N domain
OFKINFCL_01753 4.4e-216 fliK N Flagellar hook-length control protein
OFKINFCL_01754 1.7e-72 flgD N Flagellar basal body rod modification protein
OFKINFCL_01755 8.2e-140 flgG N Flagellar basal body rod
OFKINFCL_01756 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
OFKINFCL_01757 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OFKINFCL_01758 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OFKINFCL_01759 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
OFKINFCL_01760 2.7e-96 fliZ N Flagellar biosynthesis protein, FliO
OFKINFCL_01761 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
OFKINFCL_01762 2.2e-36 fliQ N Role in flagellar biosynthesis
OFKINFCL_01763 3.6e-132 fliR N Flagellar biosynthetic protein FliR
OFKINFCL_01764 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OFKINFCL_01765 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OFKINFCL_01766 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
OFKINFCL_01767 7.5e-158 flhG D Belongs to the ParA family
OFKINFCL_01768 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
OFKINFCL_01769 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
OFKINFCL_01770 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
OFKINFCL_01771 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
OFKINFCL_01772 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
OFKINFCL_01773 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFKINFCL_01774 1.3e-77 ylxL
OFKINFCL_01775 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
OFKINFCL_01776 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OFKINFCL_01777 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OFKINFCL_01778 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OFKINFCL_01779 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OFKINFCL_01780 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
OFKINFCL_01781 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
OFKINFCL_01782 7.7e-233 rasP M zinc metalloprotease
OFKINFCL_01783 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OFKINFCL_01784 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OFKINFCL_01785 1.6e-79 rimP S Required for maturation of 30S ribosomal subunits
OFKINFCL_01786 1.1e-203 nusA K Participates in both transcription termination and antitermination
OFKINFCL_01787 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
OFKINFCL_01788 3.1e-47 ylxQ J ribosomal protein
OFKINFCL_01789 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OFKINFCL_01790 3.9e-44 ylxP S protein conserved in bacteria
OFKINFCL_01791 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OFKINFCL_01792 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OFKINFCL_01793 2.3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OFKINFCL_01794 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OFKINFCL_01795 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
OFKINFCL_01796 2.1e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
OFKINFCL_01797 4.4e-233 pepR S Belongs to the peptidase M16 family
OFKINFCL_01798 2.6e-42 ymxH S YlmC YmxH family
OFKINFCL_01799 1.5e-161 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
OFKINFCL_01800 1.1e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
OFKINFCL_01801 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OFKINFCL_01802 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OFKINFCL_01803 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OFKINFCL_01804 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OFKINFCL_01805 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
OFKINFCL_01806 5.8e-32 S YlzJ-like protein
OFKINFCL_01807 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OFKINFCL_01808 1.4e-133 ymfC K Transcriptional regulator
OFKINFCL_01809 3.8e-205 ymfD EGP Major facilitator Superfamily
OFKINFCL_01810 7e-234 ymfF S Peptidase M16
OFKINFCL_01811 5.1e-240 ymfH S zinc protease
OFKINFCL_01812 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
OFKINFCL_01813 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
OFKINFCL_01814 2.7e-143 ymfK S Protein of unknown function (DUF3388)
OFKINFCL_01815 1.9e-124 ymfM S protein conserved in bacteria
OFKINFCL_01816 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OFKINFCL_01817 1.3e-235 cinA 3.5.1.42 S Belongs to the CinA family
OFKINFCL_01818 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OFKINFCL_01819 1.8e-215 pbpX V Beta-lactamase
OFKINFCL_01820 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
OFKINFCL_01821 1.9e-152 ymdB S protein conserved in bacteria
OFKINFCL_01822 1.2e-36 spoVS S Stage V sporulation protein S
OFKINFCL_01823 6e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
OFKINFCL_01824 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OFKINFCL_01825 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OFKINFCL_01826 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
OFKINFCL_01827 2.2e-88 cotE S Spore coat protein
OFKINFCL_01828 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OFKINFCL_01829 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OFKINFCL_01830 8.9e-70 S Regulatory protein YrvL
OFKINFCL_01831 1.2e-97 ymcC S Membrane
OFKINFCL_01832 4.4e-109 pksA K Transcriptional regulator
OFKINFCL_01833 4.2e-129 pksB 3.1.2.6 S Polyketide biosynthesis
OFKINFCL_01834 4.1e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OFKINFCL_01835 2.7e-185 pksD Q Acyl transferase domain
OFKINFCL_01836 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OFKINFCL_01837 1.4e-37 acpK IQ Phosphopantetheine attachment site
OFKINFCL_01838 4.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OFKINFCL_01839 3.9e-245 pksG 2.3.3.10 I synthase
OFKINFCL_01840 7.2e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
OFKINFCL_01841 2.3e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
OFKINFCL_01842 0.0 rhiB IQ polyketide synthase
OFKINFCL_01843 0.0 pfaA Q Polyketide synthase of type I
OFKINFCL_01844 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
OFKINFCL_01845 0.0 dhbF IQ polyketide synthase
OFKINFCL_01846 0.0 pks13 HQ Beta-ketoacyl synthase
OFKINFCL_01847 3.7e-232 cypA C Cytochrome P450
OFKINFCL_01848 4.4e-61 ymzB
OFKINFCL_01849 8.1e-162 ymaE S Metallo-beta-lactamase superfamily
OFKINFCL_01850 1.7e-251 aprX O Belongs to the peptidase S8 family
OFKINFCL_01851 1.9e-07 K Transcriptional regulator
OFKINFCL_01852 2.1e-126 ymaC S Replication protein
OFKINFCL_01853 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
OFKINFCL_01854 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
OFKINFCL_01855 4.9e-51 ebrA P Small Multidrug Resistance protein
OFKINFCL_01857 2.1e-46 ymaF S YmaF family
OFKINFCL_01858 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OFKINFCL_01859 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
OFKINFCL_01860 8.2e-23
OFKINFCL_01861 4.5e-22 ymzA
OFKINFCL_01862 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
OFKINFCL_01863 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OFKINFCL_01864 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OFKINFCL_01865 2e-109 ymaB
OFKINFCL_01866 5.2e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OFKINFCL_01867 1.7e-176 spoVK O stage V sporulation protein K
OFKINFCL_01868 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OFKINFCL_01869 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
OFKINFCL_01870 3.3e-68 glnR K transcriptional
OFKINFCL_01871 7e-261 glnA 6.3.1.2 E glutamine synthetase
OFKINFCL_01872 2.9e-10
OFKINFCL_01874 1.4e-37
OFKINFCL_01875 8.9e-90 G SMI1-KNR4 cell-wall
OFKINFCL_01876 2.6e-115 ynaC
OFKINFCL_01877 2.9e-96 ynaD J Acetyltransferase (GNAT) domain
OFKINFCL_01879 2.6e-73 S CAAX protease self-immunity
OFKINFCL_01880 4.7e-08 S Uncharacterised protein family (UPF0715)
OFKINFCL_01881 5.5e-20 K Cro/C1-type HTH DNA-binding domain
OFKINFCL_01882 4.2e-110 ynaE S Domain of unknown function (DUF3885)
OFKINFCL_01885 1.2e-25 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
OFKINFCL_01886 3.9e-254 xynT G MFS/sugar transport protein
OFKINFCL_01887 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
OFKINFCL_01888 6.8e-212 xylR GK ROK family
OFKINFCL_01889 6.4e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
OFKINFCL_01890 5.1e-292 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
OFKINFCL_01891 1.1e-110 yokF 3.1.31.1 L RNA catabolic process
OFKINFCL_01892 4.7e-255 iolT EGP Major facilitator Superfamily
OFKINFCL_01893 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OFKINFCL_01894 4.5e-82 yncE S Protein of unknown function (DUF2691)
OFKINFCL_01895 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OFKINFCL_01896 8.9e-15
OFKINFCL_01899 2.1e-162 S Thymidylate synthase
OFKINFCL_01901 3.2e-133 S Domain of unknown function, YrpD
OFKINFCL_01904 7.9e-25 tatA U protein secretion
OFKINFCL_01905 4.1e-71
OFKINFCL_01906 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
OFKINFCL_01909 2.8e-52 gerAA EG Spore germination protein
OFKINFCL_01910 4.8e-144 gerAA EG Spore germination protein
OFKINFCL_01911 7.6e-88 gerLC S Spore germination protein
OFKINFCL_01912 1.8e-81 yndG S DoxX-like family
OFKINFCL_01913 1.9e-115 yndH S Domain of unknown function (DUF4166)
OFKINFCL_01914 7.8e-294 yndJ S YndJ-like protein
OFKINFCL_01916 4.7e-137 yndL S Replication protein
OFKINFCL_01917 5.8e-74 yndM S Protein of unknown function (DUF2512)
OFKINFCL_01918 5.8e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
OFKINFCL_01919 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OFKINFCL_01920 9.9e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
OFKINFCL_01921 4.5e-112 yneB L resolvase
OFKINFCL_01922 1.3e-32 ynzC S UPF0291 protein
OFKINFCL_01923 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OFKINFCL_01924 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
OFKINFCL_01925 1.8e-28 yneF S UPF0154 protein
OFKINFCL_01926 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
OFKINFCL_01927 2.1e-126 ccdA O cytochrome c biogenesis protein
OFKINFCL_01928 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
OFKINFCL_01929 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
OFKINFCL_01930 7.2e-74 yneK S Protein of unknown function (DUF2621)
OFKINFCL_01931 5.9e-64 hspX O Spore coat protein
OFKINFCL_01932 3.9e-19 sspP S Belongs to the SspP family
OFKINFCL_01933 2.2e-14 sspO S Belongs to the SspO family
OFKINFCL_01934 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OFKINFCL_01935 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OFKINFCL_01937 3.1e-08 sspN S Small acid-soluble spore protein N family
OFKINFCL_01938 3.9e-35 tlp S Belongs to the Tlp family
OFKINFCL_01939 1.6e-73 yneP S Thioesterase-like superfamily
OFKINFCL_01940 2.2e-53 yneQ
OFKINFCL_01941 4.1e-49 yneR S Belongs to the HesB IscA family
OFKINFCL_01942 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OFKINFCL_01943 6.6e-69 yccU S CoA-binding protein
OFKINFCL_01944 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OFKINFCL_01945 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OFKINFCL_01946 2.3e-12
OFKINFCL_01947 1.3e-57 ynfC
OFKINFCL_01948 3.9e-238 agcS E Sodium alanine symporter
OFKINFCL_01949 8.1e-290 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
OFKINFCL_01951 2.6e-249 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
OFKINFCL_01952 7.8e-296 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
OFKINFCL_01953 1.6e-79 yngA S membrane
OFKINFCL_01954 3.8e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OFKINFCL_01955 2.7e-103 yngC S membrane-associated protein
OFKINFCL_01956 3.3e-233 nrnB S phosphohydrolase (DHH superfamily)
OFKINFCL_01957 2e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OFKINFCL_01958 8.3e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OFKINFCL_01959 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
OFKINFCL_01960 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
OFKINFCL_01961 2.9e-246 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
OFKINFCL_01962 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OFKINFCL_01963 3.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
OFKINFCL_01964 1.1e-302 yngK T Glycosyl hydrolase-like 10
OFKINFCL_01965 1.1e-63 yngL S Protein of unknown function (DUF1360)
OFKINFCL_01966 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
OFKINFCL_01967 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFKINFCL_01968 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFKINFCL_01969 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFKINFCL_01970 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFKINFCL_01971 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFKINFCL_01972 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFKINFCL_01973 3.4e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
OFKINFCL_01974 8.1e-190 yoxA 5.1.3.3 G Aldose 1-epimerase
OFKINFCL_01975 2.3e-246 yoeA V MATE efflux family protein
OFKINFCL_01976 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
OFKINFCL_01978 2.2e-96 L Integrase
OFKINFCL_01979 3e-34 yoeD G Helix-turn-helix domain
OFKINFCL_01980 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OFKINFCL_01981 2.5e-158 gltR1 K Transcriptional regulator
OFKINFCL_01982 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
OFKINFCL_01983 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
OFKINFCL_01984 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
OFKINFCL_01985 1.3e-154 gltC K Transcriptional regulator
OFKINFCL_01986 7.8e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OFKINFCL_01987 3.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OFKINFCL_01988 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
OFKINFCL_01989 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OFKINFCL_01990 2.8e-40 yoxC S Bacterial protein of unknown function (DUF948)
OFKINFCL_01991 1e-139 yoxB
OFKINFCL_01992 1.3e-93 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OFKINFCL_01993 1.5e-127 V ABC-2 family transporter protein
OFKINFCL_01994 1.9e-93 V ABC-2 family transporter protein
OFKINFCL_01995 2.8e-139 V AAA domain, putative AbiEii toxin, Type IV TA system
OFKINFCL_01996 3e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
OFKINFCL_01997 8.9e-234 yoaB EGP Major facilitator Superfamily
OFKINFCL_01998 6.7e-281 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
OFKINFCL_01999 2.9e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OFKINFCL_02000 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OFKINFCL_02001 1.4e-33 yoaF
OFKINFCL_02002 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
OFKINFCL_02003 7.7e-13
OFKINFCL_02004 7.7e-35 S Protein of unknown function (DUF4025)
OFKINFCL_02005 7e-181 mcpU NT methyl-accepting chemotaxis protein
OFKINFCL_02006 5.6e-280 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
OFKINFCL_02007 1.1e-132 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
OFKINFCL_02008 6.8e-111 yoaK S Membrane
OFKINFCL_02009 2.8e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
OFKINFCL_02010 6.6e-130 yoqW S Belongs to the SOS response-associated peptidase family
OFKINFCL_02013 1.7e-164 oxdC 4.1.1.2 G Oxalate decarboxylase
OFKINFCL_02015 2.1e-145 yoaP 3.1.3.18 K YoaP-like
OFKINFCL_02016 2.7e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
OFKINFCL_02017 1.8e-84
OFKINFCL_02018 2.1e-171 yoaR V vancomycin resistance protein
OFKINFCL_02019 9.6e-75 yoaS S Protein of unknown function (DUF2975)
OFKINFCL_02020 1.3e-29 yozG K Transcriptional regulator
OFKINFCL_02021 1.4e-147 yoaT S Protein of unknown function (DUF817)
OFKINFCL_02022 2.8e-157 yoaU K LysR substrate binding domain
OFKINFCL_02023 3.7e-157 yijE EG EamA-like transporter family
OFKINFCL_02024 3.7e-78 yoaW
OFKINFCL_02025 1e-116 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
OFKINFCL_02026 5.9e-166 bla 3.5.2.6 V beta-lactamase
OFKINFCL_02029 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
OFKINFCL_02030 3.1e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
OFKINFCL_02031 2.1e-12 S YolD-like protein
OFKINFCL_02032 1.3e-40
OFKINFCL_02034 6.3e-47
OFKINFCL_02035 9.7e-85 S SMI1-KNR4 cell-wall
OFKINFCL_02036 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OFKINFCL_02037 1.1e-101 yokH G SMI1 / KNR4 family
OFKINFCL_02038 1.7e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
OFKINFCL_02039 6.4e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
OFKINFCL_02040 1.3e-131 yobQ K helix_turn_helix, arabinose operon control protein
OFKINFCL_02041 2e-140 yobR 2.3.1.1 J FR47-like protein
OFKINFCL_02042 1.3e-94 yobS K Transcriptional regulator
OFKINFCL_02043 6.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
OFKINFCL_02044 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
OFKINFCL_02045 1.4e-175 yobV K WYL domain
OFKINFCL_02046 7.2e-95 yobW
OFKINFCL_02047 1e-51 czrA K transcriptional
OFKINFCL_02048 2.4e-108 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OFKINFCL_02049 1.5e-92 yozB S membrane
OFKINFCL_02050 1.4e-101
OFKINFCL_02051 4.9e-13
OFKINFCL_02052 8e-93 yocC
OFKINFCL_02053 9.3e-186 yocD 3.4.17.13 V peptidase S66
OFKINFCL_02054 3.4e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
OFKINFCL_02055 4.6e-197 desK 2.7.13.3 T Histidine kinase
OFKINFCL_02056 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFKINFCL_02057 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
OFKINFCL_02058 0.0 recQ 3.6.4.12 L DNA helicase
OFKINFCL_02060 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OFKINFCL_02061 7.4e-83 dksA T general stress protein
OFKINFCL_02062 5.4e-53 yocL
OFKINFCL_02063 6.2e-32
OFKINFCL_02064 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
OFKINFCL_02065 1.1e-40 yozN
OFKINFCL_02066 1.9e-36 yocN
OFKINFCL_02067 4.2e-56 yozO S Bacterial PH domain
OFKINFCL_02068 2.7e-31 yozC
OFKINFCL_02069 1.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
OFKINFCL_02070 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
OFKINFCL_02071 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
OFKINFCL_02072 4.5e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OFKINFCL_02073 4.3e-167 yocS S -transporter
OFKINFCL_02074 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
OFKINFCL_02075 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
OFKINFCL_02076 0.0 yojO P Von Willebrand factor
OFKINFCL_02077 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
OFKINFCL_02078 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OFKINFCL_02079 1.9e-196 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OFKINFCL_02080 9e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
OFKINFCL_02081 9.9e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OFKINFCL_02083 4.2e-245 norM V Multidrug efflux pump
OFKINFCL_02084 4.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OFKINFCL_02085 2.1e-125 yojG S deacetylase
OFKINFCL_02086 2.2e-60 yojF S Protein of unknown function (DUF1806)
OFKINFCL_02087 1.5e-43
OFKINFCL_02088 8.6e-162 rarD S -transporter
OFKINFCL_02089 1.3e-60 yozR S COG0071 Molecular chaperone (small heat shock protein)
OFKINFCL_02090 3.4e-09
OFKINFCL_02091 5.6e-202 gntP EG COG2610 H gluconate symporter and related permeases
OFKINFCL_02092 8e-64 yodA S tautomerase
OFKINFCL_02093 5.7e-55 yodB K transcriptional
OFKINFCL_02094 1.4e-107 yodC C nitroreductase
OFKINFCL_02095 1.1e-112 mhqD S Carboxylesterase
OFKINFCL_02096 3.2e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
OFKINFCL_02097 6.2e-28 S Protein of unknown function (DUF3311)
OFKINFCL_02098 3.3e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OFKINFCL_02099 1.8e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
OFKINFCL_02100 6.3e-128 yodH Q Methyltransferase
OFKINFCL_02101 5.2e-24 yodI
OFKINFCL_02102 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
OFKINFCL_02103 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
OFKINFCL_02104 5.3e-09
OFKINFCL_02105 3.6e-54 yodL S YodL-like
OFKINFCL_02106 7.8e-106 yodM 3.6.1.27 I Acid phosphatase homologues
OFKINFCL_02107 2.8e-24 yozD S YozD-like protein
OFKINFCL_02109 1.6e-123 yodN
OFKINFCL_02110 1.4e-36 yozE S Belongs to the UPF0346 family
OFKINFCL_02111 2.9e-47 yokU S YokU-like protein, putative antitoxin
OFKINFCL_02112 4.4e-277 kamA 5.4.3.2 E lysine 2,3-aminomutase
OFKINFCL_02113 7.9e-154 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
OFKINFCL_02114 4.2e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
OFKINFCL_02115 2e-115 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OFKINFCL_02116 3.2e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OFKINFCL_02117 3.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OFKINFCL_02119 1.2e-143 yiiD K acetyltransferase
OFKINFCL_02120 8.5e-256 cgeD M maturation of the outermost layer of the spore
OFKINFCL_02121 5.9e-38 cgeC
OFKINFCL_02122 1.2e-65 cgeA
OFKINFCL_02123 1.1e-186 cgeB S Spore maturation protein
OFKINFCL_02124 3.7e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
OFKINFCL_02125 6.2e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
OFKINFCL_02127 2.7e-103 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OFKINFCL_02128 8.4e-11 K Cro/C1-type HTH DNA-binding domain
OFKINFCL_02131 2.4e-42
OFKINFCL_02132 7.2e-163 S Calcineurin-like phosphoesterase
OFKINFCL_02133 2.5e-30 sspB S spore protein
OFKINFCL_02135 3.9e-67
OFKINFCL_02138 1.6e-157 S Thymidylate synthase
OFKINFCL_02139 2.6e-08 S Protein of unknown function (DUF1643)
OFKINFCL_02142 1.3e-73 yosT L Bacterial transcription activator, effector binding domain
OFKINFCL_02143 1.1e-71 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OFKINFCL_02144 4.5e-10
OFKINFCL_02145 4.9e-35 O Glutaredoxin
OFKINFCL_02146 1.6e-185 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OFKINFCL_02148 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OFKINFCL_02149 2.5e-65 S NrdI Flavodoxin like
OFKINFCL_02159 7.6e-51 M self proteolysis
OFKINFCL_02166 7e-81 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
OFKINFCL_02169 4.3e-23 S protein conserved in bacteria
OFKINFCL_02170 1.5e-292 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
OFKINFCL_02171 1.9e-168 S PD-(D/E)XK nuclease superfamily
OFKINFCL_02172 2e-151 3.6.4.12 L DNA primase activity
OFKINFCL_02173 2e-240 3.6.4.12 L DnaB-like helicase C terminal domain
OFKINFCL_02174 1.6e-36 KLT RIO1 family
OFKINFCL_02184 1.2e-230 S DNA replication origin binding
OFKINFCL_02187 4.3e-16
OFKINFCL_02188 3.2e-53 bldD K domain, Protein
OFKINFCL_02189 4.3e-46
OFKINFCL_02192 0.0
OFKINFCL_02193 1.8e-33 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OFKINFCL_02195 1.2e-22 S Calcineurin-like phosphoesterase superfamily domain
OFKINFCL_02196 4.9e-131 S Calcineurin-like phosphoesterase superfamily domain
OFKINFCL_02200 9.1e-175
OFKINFCL_02201 0.0 gp17a S Terminase-like family
OFKINFCL_02202 1.6e-277
OFKINFCL_02203 1.2e-258
OFKINFCL_02204 5.1e-93
OFKINFCL_02205 8.2e-185
OFKINFCL_02206 1.1e-80
OFKINFCL_02207 1.1e-63
OFKINFCL_02209 6.5e-119
OFKINFCL_02210 4.2e-89
OFKINFCL_02211 8.1e-131
OFKINFCL_02212 1.6e-87
OFKINFCL_02215 1.9e-51
OFKINFCL_02216 2e-54
OFKINFCL_02217 7.4e-59
OFKINFCL_02218 1e-56
OFKINFCL_02219 3e-123 xerH L Belongs to the 'phage' integrase family
OFKINFCL_02221 5.3e-93
OFKINFCL_02223 0.0 S peptidoglycan catabolic process
OFKINFCL_02224 1.3e-83 S Phage tail protein
OFKINFCL_02225 3.6e-301 S Pfam Transposase IS66
OFKINFCL_02226 1.1e-99
OFKINFCL_02227 1.4e-54
OFKINFCL_02229 3.3e-10 S Phage uncharacterised protein (Phage_XkdX)
OFKINFCL_02230 2.5e-07
OFKINFCL_02231 3.7e-175 S N-acetylmuramoyl-L-alanine amidase activity
OFKINFCL_02233 9.2e-37 S Bacteriophage holin
OFKINFCL_02234 4.8e-93 S aspartate phosphatase
OFKINFCL_02236 9.7e-74
OFKINFCL_02237 2.6e-118 J tRNA cytidylyltransferase activity
OFKINFCL_02238 1.2e-233 S impB/mucB/samB family C-terminal domain
OFKINFCL_02239 1.6e-52 S YolD-like protein
OFKINFCL_02241 5.1e-37
OFKINFCL_02243 4e-09 S Domain of unknown function (DUF4879)
OFKINFCL_02244 4.4e-97 J Acetyltransferase (GNAT) domain
OFKINFCL_02245 3e-20 yokK S SMI1 / KNR4 family
OFKINFCL_02246 1.1e-59 yokK S SMI1-KNR4 cell-wall
OFKINFCL_02247 4.8e-76 S SMI1-KNR4 cell-wall
OFKINFCL_02248 1.6e-55 S SMI1-KNR4 cell-wall
OFKINFCL_02249 2.5e-274 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OFKINFCL_02250 2.6e-65 G SMI1-KNR4 cell-wall
OFKINFCL_02251 1.6e-141 S Protein of unknown function (DUF4238)
OFKINFCL_02252 7.3e-105 yokF 3.1.31.1 L RNA catabolic process
OFKINFCL_02253 2e-81 yhbS S family acetyltransferase
OFKINFCL_02255 7.6e-241 yokA L Recombinase
OFKINFCL_02256 4.1e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
OFKINFCL_02257 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
OFKINFCL_02258 1e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OFKINFCL_02259 1.6e-70 ypoP K transcriptional
OFKINFCL_02260 3.4e-223 mepA V MATE efflux family protein
OFKINFCL_02261 5.5e-29 ypmT S Uncharacterized ympT
OFKINFCL_02262 5e-99 ypmS S protein conserved in bacteria
OFKINFCL_02263 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
OFKINFCL_02264 3.5e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
OFKINFCL_02265 3.1e-40 ypmP S Protein of unknown function (DUF2535)
OFKINFCL_02266 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OFKINFCL_02267 2.6e-183 pspF K Transcriptional regulator
OFKINFCL_02268 4.2e-110 hlyIII S protein, Hemolysin III
OFKINFCL_02269 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OFKINFCL_02270 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OFKINFCL_02271 7.6e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OFKINFCL_02272 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OFKINFCL_02273 8.6e-113 ypjP S YpjP-like protein
OFKINFCL_02274 1.6e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
OFKINFCL_02275 1.7e-75 yphP S Belongs to the UPF0403 family
OFKINFCL_02276 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OFKINFCL_02277 5.8e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
OFKINFCL_02278 3.9e-105 ypgQ S phosphohydrolase
OFKINFCL_02279 4.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
OFKINFCL_02280 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OFKINFCL_02282 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
OFKINFCL_02283 7.9e-31 cspD K Cold-shock protein
OFKINFCL_02284 3.8e-16 degR
OFKINFCL_02285 8.1e-31 S Protein of unknown function (DUF2564)
OFKINFCL_02286 3e-29 ypeQ S Zinc-finger
OFKINFCL_02287 4.7e-135 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
OFKINFCL_02288 1.3e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OFKINFCL_02289 2.5e-68 rnhA 3.1.26.4 L Ribonuclease
OFKINFCL_02291 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
OFKINFCL_02292 2e-07
OFKINFCL_02293 1e-38 ypbS S Protein of unknown function (DUF2533)
OFKINFCL_02294 0.0 ypbR S Dynamin family
OFKINFCL_02295 5.1e-87 ypbQ S protein conserved in bacteria
OFKINFCL_02296 1.5e-205 bcsA Q Naringenin-chalcone synthase
OFKINFCL_02297 2.9e-227 pbuX F xanthine
OFKINFCL_02298 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OFKINFCL_02299 3.9e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OFKINFCL_02300 2.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
OFKINFCL_02301 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
OFKINFCL_02302 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
OFKINFCL_02303 4.1e-184 ptxS K transcriptional
OFKINFCL_02304 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OFKINFCL_02305 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFKINFCL_02306 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
OFKINFCL_02308 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OFKINFCL_02309 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OFKINFCL_02310 3.3e-92 ypsA S Belongs to the UPF0398 family
OFKINFCL_02311 5.1e-237 yprB L RNase_H superfamily
OFKINFCL_02312 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
OFKINFCL_02313 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
OFKINFCL_02314 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
OFKINFCL_02315 1.2e-48 yppG S YppG-like protein
OFKINFCL_02317 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
OFKINFCL_02320 3.7e-187 yppC S Protein of unknown function (DUF2515)
OFKINFCL_02321 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OFKINFCL_02322 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
OFKINFCL_02323 1.8e-92 ypoC
OFKINFCL_02324 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OFKINFCL_02325 5.7e-129 dnaD L DNA replication protein DnaD
OFKINFCL_02326 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
OFKINFCL_02327 7.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
OFKINFCL_02328 2.2e-79 ypmB S protein conserved in bacteria
OFKINFCL_02329 1.9e-22 ypmA S Protein of unknown function (DUF4264)
OFKINFCL_02330 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OFKINFCL_02331 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OFKINFCL_02332 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OFKINFCL_02333 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
OFKINFCL_02334 2.5e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OFKINFCL_02335 7.5e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OFKINFCL_02336 1.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
OFKINFCL_02337 4.5e-129 bshB1 S proteins, LmbE homologs
OFKINFCL_02338 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
OFKINFCL_02339 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OFKINFCL_02340 2.6e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
OFKINFCL_02341 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
OFKINFCL_02342 1e-142 ypjB S sporulation protein
OFKINFCL_02343 3.4e-98 ypjA S membrane
OFKINFCL_02344 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
OFKINFCL_02345 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
OFKINFCL_02346 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
OFKINFCL_02347 1.4e-75 ypiF S Protein of unknown function (DUF2487)
OFKINFCL_02348 2.8e-99 ypiB S Belongs to the UPF0302 family
OFKINFCL_02349 2.7e-233 S COG0457 FOG TPR repeat
OFKINFCL_02350 3.8e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
OFKINFCL_02351 5.8e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
OFKINFCL_02352 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OFKINFCL_02353 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
OFKINFCL_02354 5.2e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OFKINFCL_02355 2.7e-117 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
OFKINFCL_02356 9.5e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
OFKINFCL_02357 5.1e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OFKINFCL_02358 4e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OFKINFCL_02359 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
OFKINFCL_02360 5.8e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OFKINFCL_02361 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OFKINFCL_02362 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
OFKINFCL_02363 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
OFKINFCL_02364 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OFKINFCL_02365 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OFKINFCL_02366 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
OFKINFCL_02367 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
OFKINFCL_02368 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
OFKINFCL_02369 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OFKINFCL_02370 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OFKINFCL_02371 5.4e-138 yphF
OFKINFCL_02372 1.6e-18 yphE S Protein of unknown function (DUF2768)
OFKINFCL_02373 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OFKINFCL_02374 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OFKINFCL_02375 7.9e-28 ypzH
OFKINFCL_02376 2.5e-161 seaA S YIEGIA protein
OFKINFCL_02377 1.3e-102 yphA
OFKINFCL_02378 1.4e-07 S YpzI-like protein
OFKINFCL_02379 1.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OFKINFCL_02380 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
OFKINFCL_02381 1.6e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OFKINFCL_02382 1.8e-23 S Family of unknown function (DUF5359)
OFKINFCL_02383 2e-112 ypfA M Flagellar protein YcgR
OFKINFCL_02384 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
OFKINFCL_02385 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
OFKINFCL_02386 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
OFKINFCL_02387 6.2e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
OFKINFCL_02388 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OFKINFCL_02389 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OFKINFCL_02390 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
OFKINFCL_02391 2.8e-81 ypbF S Protein of unknown function (DUF2663)
OFKINFCL_02392 1.3e-75 ypbE M Lysin motif
OFKINFCL_02393 1.1e-99 ypbD S metal-dependent membrane protease
OFKINFCL_02394 3.2e-286 recQ 3.6.4.12 L DNA helicase
OFKINFCL_02395 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
OFKINFCL_02396 4.7e-41 fer C Ferredoxin
OFKINFCL_02397 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OFKINFCL_02398 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OFKINFCL_02399 1e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
OFKINFCL_02400 2.5e-195 rsiX
OFKINFCL_02401 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
OFKINFCL_02402 0.0 resE 2.7.13.3 T Histidine kinase
OFKINFCL_02403 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFKINFCL_02404 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
OFKINFCL_02405 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
OFKINFCL_02406 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
OFKINFCL_02407 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OFKINFCL_02408 1.9e-87 spmB S Spore maturation protein
OFKINFCL_02409 3.5e-103 spmA S Spore maturation protein
OFKINFCL_02410 1.4e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
OFKINFCL_02411 1.7e-96 ypuI S Protein of unknown function (DUF3907)
OFKINFCL_02412 3.5e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OFKINFCL_02413 3.8e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OFKINFCL_02414 2.7e-91 ypuF S Domain of unknown function (DUF309)
OFKINFCL_02415 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFKINFCL_02416 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OFKINFCL_02417 1.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OFKINFCL_02418 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
OFKINFCL_02419 1.4e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OFKINFCL_02420 6.6e-54 ypuD
OFKINFCL_02421 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OFKINFCL_02422 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
OFKINFCL_02423 7e-16 S SNARE associated Golgi protein
OFKINFCL_02426 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OFKINFCL_02427 8.1e-149 ypuA S Secreted protein
OFKINFCL_02428 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OFKINFCL_02429 4e-273 spoVAF EG Stage V sporulation protein AF
OFKINFCL_02430 1.4e-110 spoVAEA S stage V sporulation protein
OFKINFCL_02431 2.2e-57 spoVAEB S stage V sporulation protein
OFKINFCL_02432 9e-192 spoVAD I Stage V sporulation protein AD
OFKINFCL_02433 2.3e-78 spoVAC S stage V sporulation protein AC
OFKINFCL_02434 1e-67 spoVAB S Stage V sporulation protein AB
OFKINFCL_02435 9.6e-112 spoVAA S Stage V sporulation protein AA
OFKINFCL_02436 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFKINFCL_02437 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
OFKINFCL_02438 1.9e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
OFKINFCL_02439 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
OFKINFCL_02440 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OFKINFCL_02441 1.1e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
OFKINFCL_02442 5.7e-166 xerD L recombinase XerD
OFKINFCL_02443 1.4e-36 S Protein of unknown function (DUF4227)
OFKINFCL_02444 2.4e-80 fur P Belongs to the Fur family
OFKINFCL_02445 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
OFKINFCL_02446 2.2e-31 yqkK
OFKINFCL_02447 2.1e-241 mleA 1.1.1.38 C malic enzyme
OFKINFCL_02448 3.1e-235 mleN C Na H antiporter
OFKINFCL_02449 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
OFKINFCL_02450 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
OFKINFCL_02451 4.5e-58 ansR K Transcriptional regulator
OFKINFCL_02452 1.2e-219 yqxK 3.6.4.12 L DNA helicase
OFKINFCL_02453 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
OFKINFCL_02455 6.3e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
OFKINFCL_02456 3.1e-12 yqkE S Protein of unknown function (DUF3886)
OFKINFCL_02457 1.2e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
OFKINFCL_02458 3.9e-37 yqkC S Protein of unknown function (DUF2552)
OFKINFCL_02459 2.8e-54 yqkB S Belongs to the HesB IscA family
OFKINFCL_02460 1.1e-192 yqkA K GrpB protein
OFKINFCL_02461 3.5e-55 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
OFKINFCL_02462 3.6e-87 yqjY K acetyltransferase
OFKINFCL_02463 7.5e-50 S YolD-like protein
OFKINFCL_02464 2.7e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OFKINFCL_02466 5.8e-225 yqjV G Major Facilitator Superfamily
OFKINFCL_02468 2e-70 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OFKINFCL_02469 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
OFKINFCL_02470 3.9e-259 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
OFKINFCL_02471 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
OFKINFCL_02472 8.3e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
OFKINFCL_02473 1.1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OFKINFCL_02474 0.0 rocB E arginine degradation protein
OFKINFCL_02475 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
OFKINFCL_02476 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OFKINFCL_02477 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OFKINFCL_02478 8.5e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OFKINFCL_02479 1.4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OFKINFCL_02480 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OFKINFCL_02481 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OFKINFCL_02482 4.5e-24 yqzJ
OFKINFCL_02483 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OFKINFCL_02484 3.4e-140 yqjF S Uncharacterized conserved protein (COG2071)
OFKINFCL_02485 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
OFKINFCL_02486 3.5e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OFKINFCL_02487 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
OFKINFCL_02489 4.4e-97 yqjB S protein conserved in bacteria
OFKINFCL_02490 3.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
OFKINFCL_02491 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OFKINFCL_02492 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
OFKINFCL_02493 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
OFKINFCL_02494 9.3e-77 yqiW S Belongs to the UPF0403 family
OFKINFCL_02495 3.4e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OFKINFCL_02496 3.3e-206 norA EGP Major facilitator Superfamily
OFKINFCL_02497 1.3e-151 bmrR K helix_turn_helix, mercury resistance
OFKINFCL_02498 2.9e-219 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OFKINFCL_02499 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OFKINFCL_02500 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OFKINFCL_02501 2.2e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OFKINFCL_02502 3.5e-202 buk 2.7.2.7 C Belongs to the acetokinase family
OFKINFCL_02503 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
OFKINFCL_02504 5.1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
OFKINFCL_02505 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
OFKINFCL_02506 4e-34 yqzF S Protein of unknown function (DUF2627)
OFKINFCL_02507 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OFKINFCL_02508 2.4e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
OFKINFCL_02509 2.9e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
OFKINFCL_02510 6.3e-210 mmgC I acyl-CoA dehydrogenase
OFKINFCL_02511 7.5e-155 hbdA 1.1.1.157 I Dehydrogenase
OFKINFCL_02512 4.5e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
OFKINFCL_02513 3.2e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OFKINFCL_02514 1.7e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
OFKINFCL_02515 2.3e-26
OFKINFCL_02516 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
OFKINFCL_02518 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
OFKINFCL_02519 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
OFKINFCL_02520 6.5e-307 recN L May be involved in recombinational repair of damaged DNA
OFKINFCL_02521 3.9e-78 argR K Regulates arginine biosynthesis genes
OFKINFCL_02522 1.9e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
OFKINFCL_02523 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OFKINFCL_02524 5e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OFKINFCL_02525 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OFKINFCL_02526 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OFKINFCL_02527 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OFKINFCL_02528 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OFKINFCL_02529 2.1e-67 yqhY S protein conserved in bacteria
OFKINFCL_02530 5.9e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
OFKINFCL_02531 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OFKINFCL_02532 9.9e-91 spoIIIAH S SpoIIIAH-like protein
OFKINFCL_02533 8.5e-109 spoIIIAG S stage III sporulation protein AG
OFKINFCL_02534 4.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
OFKINFCL_02535 8.4e-197 spoIIIAE S stage III sporulation protein AE
OFKINFCL_02536 2.3e-58 spoIIIAD S Stage III sporulation protein AD
OFKINFCL_02537 7.6e-29 spoIIIAC S stage III sporulation protein AC
OFKINFCL_02538 1.1e-84 spoIIIAB S Stage III sporulation protein
OFKINFCL_02539 3e-170 spoIIIAA S stage III sporulation protein AA
OFKINFCL_02540 7.9e-37 yqhV S Protein of unknown function (DUF2619)
OFKINFCL_02541 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OFKINFCL_02542 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OFKINFCL_02543 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
OFKINFCL_02544 2.3e-93 yqhR S Conserved membrane protein YqhR
OFKINFCL_02545 8e-174 yqhQ S Protein of unknown function (DUF1385)
OFKINFCL_02546 2.2e-61 yqhP
OFKINFCL_02547 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
OFKINFCL_02548 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
OFKINFCL_02549 2.2e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
OFKINFCL_02550 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
OFKINFCL_02551 2.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OFKINFCL_02552 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OFKINFCL_02553 2.1e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
OFKINFCL_02554 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OFKINFCL_02555 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
OFKINFCL_02556 1.2e-24 sinI S Anti-repressor SinI
OFKINFCL_02557 1e-54 sinR K transcriptional
OFKINFCL_02558 6.6e-142 tasA S Cell division protein FtsN
OFKINFCL_02559 3.3e-58 sipW 3.4.21.89 U Signal peptidase
OFKINFCL_02560 2.2e-113 yqxM
OFKINFCL_02561 7.3e-54 yqzG S Protein of unknown function (DUF3889)
OFKINFCL_02562 1.4e-26 yqzE S YqzE-like protein
OFKINFCL_02563 4e-44 S ComG operon protein 7
OFKINFCL_02564 1.2e-45 comGF U Putative Competence protein ComGF
OFKINFCL_02565 1.1e-59 comGE
OFKINFCL_02566 4.9e-70 gspH NU protein transport across the cell outer membrane
OFKINFCL_02567 6.8e-47 comGC U Required for transformation and DNA binding
OFKINFCL_02568 2.5e-173 comGB NU COG1459 Type II secretory pathway, component PulF
OFKINFCL_02569 2.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OFKINFCL_02571 1.1e-172 corA P Mg2 transporter protein
OFKINFCL_02572 1.5e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OFKINFCL_02573 6.4e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OFKINFCL_02575 2.3e-63 yqgZ 1.20.4.1 P Belongs to the ArsC family
OFKINFCL_02576 1.8e-37 yqgY S Protein of unknown function (DUF2626)
OFKINFCL_02577 4.7e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
OFKINFCL_02578 8.9e-23 yqgW S Protein of unknown function (DUF2759)
OFKINFCL_02579 6.9e-50 yqgV S Thiamine-binding protein
OFKINFCL_02580 2.7e-199 yqgU
OFKINFCL_02581 1.2e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
OFKINFCL_02582 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OFKINFCL_02583 1.5e-180 glcK 2.7.1.2 G Glucokinase
OFKINFCL_02584 4.3e-33 yqgQ S Protein conserved in bacteria
OFKINFCL_02585 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
OFKINFCL_02586 2.5e-09 yqgO
OFKINFCL_02587 5.7e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OFKINFCL_02588 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OFKINFCL_02589 2.3e-201 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
OFKINFCL_02591 9.2e-51 yqzD
OFKINFCL_02592 2.1e-71 yqzC S YceG-like family
OFKINFCL_02593 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OFKINFCL_02594 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OFKINFCL_02595 4.8e-157 pstA P Phosphate transport system permease
OFKINFCL_02596 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
OFKINFCL_02597 2e-150 pstS P Phosphate
OFKINFCL_02598 0.0 pbpA 3.4.16.4 M penicillin-binding protein
OFKINFCL_02599 2.8e-230 yqgE EGP Major facilitator superfamily
OFKINFCL_02600 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
OFKINFCL_02601 4e-73 yqgC S protein conserved in bacteria
OFKINFCL_02602 8.7e-131 yqgB S Protein of unknown function (DUF1189)
OFKINFCL_02603 1.5e-46 yqfZ M LysM domain
OFKINFCL_02604 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OFKINFCL_02605 4.3e-62 yqfX S membrane
OFKINFCL_02606 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
OFKINFCL_02607 4.2e-77 zur P Belongs to the Fur family
OFKINFCL_02608 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OFKINFCL_02609 2.1e-36 yqfT S Protein of unknown function (DUF2624)
OFKINFCL_02610 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OFKINFCL_02611 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OFKINFCL_02612 2.9e-14 yqfQ S YqfQ-like protein
OFKINFCL_02613 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OFKINFCL_02614 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OFKINFCL_02615 3e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
OFKINFCL_02616 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
OFKINFCL_02617 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OFKINFCL_02618 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OFKINFCL_02619 4.5e-88 yaiI S Belongs to the UPF0178 family
OFKINFCL_02620 1.3e-148 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OFKINFCL_02621 4.5e-112 ccpN K CBS domain
OFKINFCL_02622 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
OFKINFCL_02623 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
OFKINFCL_02624 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
OFKINFCL_02625 8.4e-19 S YqzL-like protein
OFKINFCL_02626 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OFKINFCL_02627 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OFKINFCL_02628 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
OFKINFCL_02629 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OFKINFCL_02630 0.0 yqfF S membrane-associated HD superfamily hydrolase
OFKINFCL_02632 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
OFKINFCL_02633 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
OFKINFCL_02634 2.7e-45 yqfC S sporulation protein YqfC
OFKINFCL_02635 2.4e-21 yqfB
OFKINFCL_02636 4.3e-122 yqfA S UPF0365 protein
OFKINFCL_02637 1e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
OFKINFCL_02638 2.5e-61 yqeY S Yqey-like protein
OFKINFCL_02639 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OFKINFCL_02640 8.2e-158 yqeW P COG1283 Na phosphate symporter
OFKINFCL_02641 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
OFKINFCL_02642 3e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OFKINFCL_02643 4.6e-174 prmA J Methylates ribosomal protein L11
OFKINFCL_02644 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OFKINFCL_02645 0.0 dnaK O Heat shock 70 kDa protein
OFKINFCL_02646 3.6e-73 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OFKINFCL_02647 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OFKINFCL_02648 4.5e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
OFKINFCL_02649 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OFKINFCL_02650 7.2e-53 yqxA S Protein of unknown function (DUF3679)
OFKINFCL_02651 2e-222 spoIIP M stage II sporulation protein P
OFKINFCL_02652 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OFKINFCL_02653 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
OFKINFCL_02654 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
OFKINFCL_02655 4.1e-15 S YqzM-like protein
OFKINFCL_02656 0.0 comEC S Competence protein ComEC
OFKINFCL_02657 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
OFKINFCL_02658 7.3e-104 wza L COG1555 DNA uptake protein and related DNA-binding proteins
OFKINFCL_02659 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OFKINFCL_02660 2.9e-139 yqeM Q Methyltransferase
OFKINFCL_02661 2e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OFKINFCL_02662 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
OFKINFCL_02663 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OFKINFCL_02664 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
OFKINFCL_02665 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OFKINFCL_02666 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
OFKINFCL_02667 5.3e-95 yqeG S hydrolase of the HAD superfamily
OFKINFCL_02669 3.1e-141 yqeF E GDSL-like Lipase/Acylhydrolase
OFKINFCL_02670 1.8e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OFKINFCL_02671 1.8e-105 yqeD S SNARE associated Golgi protein
OFKINFCL_02672 2.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
OFKINFCL_02673 2.3e-133 yqeB
OFKINFCL_02674 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
OFKINFCL_02675 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFKINFCL_02676 5.1e-276 cisA2 L Recombinase
OFKINFCL_02677 1.7e-141 yfiE K LysR substrate binding domain
OFKINFCL_02678 3.6e-84 E LysE type translocator
OFKINFCL_02679 9.4e-46 K regulatory protein GntR HTH
OFKINFCL_02680 1.1e-81 H PFAM Dimethylmenaquinone methyltransferase
OFKINFCL_02681 5.6e-62 dlpA H Aldolase/RraA
OFKINFCL_02682 1.8e-79 6.2.1.3 H PFAM Dimethylmenaquinone methyltransferase
OFKINFCL_02683 7.6e-116 tyrB 2.6.1.1, 2.6.1.57 E Aminotransferase, class I
OFKINFCL_02684 4e-190 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
OFKINFCL_02685 1.5e-65 S response regulator aspartate phosphatase
OFKINFCL_02687 1.4e-29
OFKINFCL_02688 1.3e-302 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OFKINFCL_02689 7.8e-82 S SMI1-KNR4 cell-wall
OFKINFCL_02690 5.7e-116 EGP Necrosis inducing protein (NPP1)
OFKINFCL_02691 6.5e-100 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OFKINFCL_02692 8.1e-27 S phage terminase, large subunit
OFKINFCL_02693 1.9e-69 yqaS L DNA packaging
OFKINFCL_02695 3.7e-26 cotD S Inner spore coat protein D
OFKINFCL_02696 1.9e-40 L Transposase
OFKINFCL_02699 1.3e-38 xkdC L IstB-like ATP binding protein
OFKINFCL_02701 2.6e-160 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
OFKINFCL_02702 5.9e-89 K Transcriptional regulator PadR-like family
OFKINFCL_02703 2.9e-96 adk 2.7.4.3 F adenylate kinase activity
OFKINFCL_02705 4.4e-94 yqaB E IrrE N-terminal-like domain
OFKINFCL_02706 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFKINFCL_02707 3.6e-112 tetR3 K Transcriptional regulator
OFKINFCL_02708 9.1e-216 mepA V Multidrug transporter MatE
OFKINFCL_02709 6e-165 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
OFKINFCL_02710 6.5e-97 yrkJ S membrane transporter protein
OFKINFCL_02711 1.6e-35 yrkI O Belongs to the sulfur carrier protein TusA family
OFKINFCL_02712 1.9e-206 yrkH P Rhodanese Homology Domain
OFKINFCL_02714 4.2e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
OFKINFCL_02715 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
OFKINFCL_02716 7.8e-39 yrkD S protein conserved in bacteria
OFKINFCL_02717 1.4e-106 yrkC G Cupin domain
OFKINFCL_02718 3.1e-150 bltR K helix_turn_helix, mercury resistance
OFKINFCL_02719 1e-210 blt EGP Major facilitator Superfamily
OFKINFCL_02720 5.9e-82 bltD 2.3.1.57 K FR47-like protein
OFKINFCL_02721 1.3e-235 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OFKINFCL_02722 6.3e-11 S YrzO-like protein
OFKINFCL_02723 1.4e-170 yrdR EG EamA-like transporter family
OFKINFCL_02724 5.6e-158 yrdQ K Transcriptional regulator
OFKINFCL_02725 3.3e-197 trkA P Oxidoreductase
OFKINFCL_02726 2.2e-147 czcD P COG1230 Co Zn Cd efflux system component
OFKINFCL_02727 1.3e-66 yodA S tautomerase
OFKINFCL_02728 1.9e-161 gltR K LysR substrate binding domain
OFKINFCL_02729 3.3e-226 brnQ E Component of the transport system for branched-chain amino acids
OFKINFCL_02730 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
OFKINFCL_02731 2.8e-137 azlC E AzlC protein
OFKINFCL_02732 8.2e-79 bkdR K helix_turn_helix ASNC type
OFKINFCL_02733 2.2e-27 yrdF K ribonuclease inhibitor
OFKINFCL_02734 7.3e-228 cypA C Cytochrome P450
OFKINFCL_02735 5.3e-28 K Acetyltransferase (GNAT) family
OFKINFCL_02736 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
OFKINFCL_02737 1.9e-57 S Protein of unknown function (DUF2568)
OFKINFCL_02739 6.4e-90 yrdA S DinB family
OFKINFCL_02740 1e-164 aadK G Streptomycin adenylyltransferase
OFKINFCL_02741 8.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OFKINFCL_02742 1.8e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OFKINFCL_02743 1.6e-123 yrpD S Domain of unknown function, YrpD
OFKINFCL_02745 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
OFKINFCL_02746 9.1e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
OFKINFCL_02747 2.9e-187 yrpG C Aldo/keto reductase family
OFKINFCL_02748 1e-224 yraO C Citrate transporter
OFKINFCL_02749 3.4e-163 yraN K Transcriptional regulator
OFKINFCL_02750 1.6e-205 yraM S PrpF protein
OFKINFCL_02751 2.3e-14 yraM S PrpF protein
OFKINFCL_02752 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
OFKINFCL_02753 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFKINFCL_02754 2.8e-151 S Alpha beta hydrolase
OFKINFCL_02755 4.9e-60 T sh3 domain protein
OFKINFCL_02756 2.4e-61 T sh3 domain protein
OFKINFCL_02757 3.8e-66 E Glyoxalase-like domain
OFKINFCL_02758 1.5e-36 yraG
OFKINFCL_02759 6.4e-63 yraF M Spore coat protein
OFKINFCL_02760 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OFKINFCL_02761 7.5e-26 yraE
OFKINFCL_02762 1.1e-49 yraD M Spore coat protein
OFKINFCL_02763 4.3e-47 yraB K helix_turn_helix, mercury resistance
OFKINFCL_02764 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
OFKINFCL_02765 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
OFKINFCL_02766 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
OFKINFCL_02767 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
OFKINFCL_02768 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
OFKINFCL_02769 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
OFKINFCL_02770 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
OFKINFCL_02771 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
OFKINFCL_02772 0.0 levR K PTS system fructose IIA component
OFKINFCL_02773 3e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
OFKINFCL_02774 3.6e-106 yrhP E LysE type translocator
OFKINFCL_02775 2e-149 yrhO K Archaeal transcriptional regulator TrmB
OFKINFCL_02776 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
OFKINFCL_02777 3.8e-151 rsiV S Protein of unknown function (DUF3298)
OFKINFCL_02778 0.0 yrhL I Acyltransferase family
OFKINFCL_02779 4e-44 yrhK S YrhK-like protein
OFKINFCL_02780 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OFKINFCL_02781 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
OFKINFCL_02782 1.1e-95 yrhH Q methyltransferase
OFKINFCL_02785 1.8e-142 focA P Formate nitrite
OFKINFCL_02787 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
OFKINFCL_02788 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
OFKINFCL_02789 4.1e-78 yrhD S Protein of unknown function (DUF1641)
OFKINFCL_02790 4.6e-35 yrhC S YrhC-like protein
OFKINFCL_02791 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OFKINFCL_02792 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
OFKINFCL_02793 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OFKINFCL_02794 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
OFKINFCL_02795 1e-25 yrzA S Protein of unknown function (DUF2536)
OFKINFCL_02796 9.3e-63 yrrS S Protein of unknown function (DUF1510)
OFKINFCL_02797 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
OFKINFCL_02798 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OFKINFCL_02799 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
OFKINFCL_02800 2.7e-246 yegQ O COG0826 Collagenase and related proteases
OFKINFCL_02801 1.1e-172 yegQ O Peptidase U32
OFKINFCL_02802 6.6e-119 yrrM 2.1.1.104 S O-methyltransferase
OFKINFCL_02803 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OFKINFCL_02804 1.2e-45 yrzB S Belongs to the UPF0473 family
OFKINFCL_02805 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OFKINFCL_02806 1.7e-41 yrzL S Belongs to the UPF0297 family
OFKINFCL_02807 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OFKINFCL_02808 4.1e-163 yrrI S AI-2E family transporter
OFKINFCL_02809 8.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OFKINFCL_02810 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
OFKINFCL_02811 3.6e-109 gluC P ABC transporter
OFKINFCL_02812 4.9e-106 glnP P ABC transporter
OFKINFCL_02813 8e-08 S Protein of unknown function (DUF3918)
OFKINFCL_02814 9.8e-31 yrzR
OFKINFCL_02815 3.9e-81 yrrD S protein conserved in bacteria
OFKINFCL_02816 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OFKINFCL_02817 1.4e-15 S COG0457 FOG TPR repeat
OFKINFCL_02818 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OFKINFCL_02819 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
OFKINFCL_02820 1.2e-70 cymR K Transcriptional regulator
OFKINFCL_02821 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
OFKINFCL_02822 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
OFKINFCL_02823 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OFKINFCL_02824 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
OFKINFCL_02826 2.1e-256 lytH 3.5.1.28 M COG3103 SH3 domain protein
OFKINFCL_02827 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OFKINFCL_02828 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OFKINFCL_02829 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OFKINFCL_02830 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OFKINFCL_02831 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
OFKINFCL_02832 3.9e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
OFKINFCL_02833 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OFKINFCL_02834 9.4e-49 yrzD S Post-transcriptional regulator
OFKINFCL_02835 4.1e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OFKINFCL_02836 1.7e-111 yrbG S membrane
OFKINFCL_02837 3.8e-73 yrzE S Protein of unknown function (DUF3792)
OFKINFCL_02838 1.1e-38 yajC U Preprotein translocase subunit YajC
OFKINFCL_02839 8.8e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OFKINFCL_02840 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OFKINFCL_02841 2.6e-18 yrzS S Protein of unknown function (DUF2905)
OFKINFCL_02842 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OFKINFCL_02843 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OFKINFCL_02844 4.8e-93 bofC S BofC C-terminal domain
OFKINFCL_02845 5.3e-253 csbX EGP Major facilitator Superfamily
OFKINFCL_02846 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
OFKINFCL_02847 6.5e-119 yrzF T serine threonine protein kinase
OFKINFCL_02849 6.8e-51 S Family of unknown function (DUF5412)
OFKINFCL_02850 2e-261 alsT E Sodium alanine symporter
OFKINFCL_02851 1.9e-127 yebC K transcriptional regulatory protein
OFKINFCL_02852 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OFKINFCL_02853 1.8e-156 safA M spore coat assembly protein SafA
OFKINFCL_02854 3.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OFKINFCL_02855 6.2e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
OFKINFCL_02856 4.3e-305 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
OFKINFCL_02857 1.9e-228 nifS 2.8.1.7 E Cysteine desulfurase
OFKINFCL_02858 1e-93 niaR S small molecule binding protein (contains 3H domain)
OFKINFCL_02859 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
OFKINFCL_02860 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
OFKINFCL_02861 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OFKINFCL_02862 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
OFKINFCL_02863 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OFKINFCL_02864 4.1e-56 ysxB J ribosomal protein
OFKINFCL_02865 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
OFKINFCL_02866 9.2e-161 spoIVFB S Stage IV sporulation protein
OFKINFCL_02867 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
OFKINFCL_02868 2.5e-144 minD D Belongs to the ParA family
OFKINFCL_02869 7.1e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OFKINFCL_02870 1.4e-84 mreD M shape-determining protein
OFKINFCL_02871 2.8e-157 mreC M Involved in formation and maintenance of cell shape
OFKINFCL_02872 1.8e-184 mreB D Rod shape-determining protein MreB
OFKINFCL_02873 1.3e-125 radC E Belongs to the UPF0758 family
OFKINFCL_02874 2.8e-102 maf D septum formation protein Maf
OFKINFCL_02875 5.1e-163 spoIIB S Sporulation related domain
OFKINFCL_02876 2.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
OFKINFCL_02877 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OFKINFCL_02878 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OFKINFCL_02879 1.6e-25
OFKINFCL_02880 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OFKINFCL_02881 2.8e-209 spoVID M stage VI sporulation protein D
OFKINFCL_02882 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OFKINFCL_02883 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
OFKINFCL_02884 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OFKINFCL_02885 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
OFKINFCL_02886 5.2e-145 hemX O cytochrome C
OFKINFCL_02887 7.7e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OFKINFCL_02888 2.4e-89 ysxD
OFKINFCL_02889 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
OFKINFCL_02890 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OFKINFCL_02891 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
OFKINFCL_02892 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OFKINFCL_02893 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OFKINFCL_02894 5.1e-187 ysoA H Tetratricopeptide repeat
OFKINFCL_02895 2.6e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OFKINFCL_02896 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OFKINFCL_02897 1.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
OFKINFCL_02898 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OFKINFCL_02899 9.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OFKINFCL_02900 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
OFKINFCL_02901 0.0 ilvB 2.2.1.6 E Acetolactate synthase
OFKINFCL_02903 2.1e-76 ysnE K acetyltransferase
OFKINFCL_02904 5.1e-131 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
OFKINFCL_02905 7.7e-133 ysnF S protein conserved in bacteria
OFKINFCL_02907 1.4e-92 ysnB S Phosphoesterase
OFKINFCL_02908 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OFKINFCL_02909 2.6e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OFKINFCL_02910 2.9e-196 gerM S COG5401 Spore germination protein
OFKINFCL_02911 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OFKINFCL_02912 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
OFKINFCL_02913 3.3e-30 gerE K Transcriptional regulator
OFKINFCL_02914 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
OFKINFCL_02915 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OFKINFCL_02916 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OFKINFCL_02917 2.4e-107 sdhC C succinate dehydrogenase
OFKINFCL_02918 1.2e-79 yslB S Protein of unknown function (DUF2507)
OFKINFCL_02919 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OFKINFCL_02920 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OFKINFCL_02921 2e-52 trxA O Belongs to the thioredoxin family
OFKINFCL_02922 4.1e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
OFKINFCL_02924 4.2e-178 etfA C Electron transfer flavoprotein
OFKINFCL_02925 1.2e-135 etfB C Electron transfer flavoprotein
OFKINFCL_02926 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OFKINFCL_02927 2.7e-100 fadR K Transcriptional regulator
OFKINFCL_02928 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OFKINFCL_02929 7.3e-68 yshE S membrane
OFKINFCL_02930 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OFKINFCL_02931 0.0 polX L COG1796 DNA polymerase IV (family X)
OFKINFCL_02932 1.3e-85 cvpA S membrane protein, required for colicin V production
OFKINFCL_02933 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OFKINFCL_02934 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OFKINFCL_02935 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OFKINFCL_02936 4.7e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OFKINFCL_02937 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OFKINFCL_02938 5.8e-32 sspI S Belongs to the SspI family
OFKINFCL_02939 2e-205 ysfB KT regulator
OFKINFCL_02940 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
OFKINFCL_02941 8.1e-257 glcF C Glycolate oxidase
OFKINFCL_02942 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
OFKINFCL_02944 0.0 cstA T Carbon starvation protein
OFKINFCL_02945 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
OFKINFCL_02946 2.2e-143 araQ G transport system permease
OFKINFCL_02947 7.1e-167 araP G carbohydrate transport
OFKINFCL_02948 8.1e-254 araN G carbohydrate transport
OFKINFCL_02949 9.8e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
OFKINFCL_02950 1.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
OFKINFCL_02951 2.4e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
OFKINFCL_02952 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
OFKINFCL_02953 5.4e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
OFKINFCL_02954 1.5e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OFKINFCL_02955 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
OFKINFCL_02956 3.5e-67 ysdB S Sigma-w pathway protein YsdB
OFKINFCL_02957 7.5e-45 ysdA S Membrane
OFKINFCL_02958 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OFKINFCL_02959 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OFKINFCL_02960 2e-55 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OFKINFCL_02963 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OFKINFCL_02964 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OFKINFCL_02965 5.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
OFKINFCL_02966 0.0 lytS 2.7.13.3 T Histidine kinase
OFKINFCL_02967 1.8e-147 ysaA S HAD-hyrolase-like
OFKINFCL_02968 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OFKINFCL_02969 1.3e-26 ytxC S YtxC-like family
OFKINFCL_02970 6e-157 ytxC S YtxC-like family
OFKINFCL_02971 2.3e-108 ytxB S SNARE associated Golgi protein
OFKINFCL_02972 3e-173 dnaI L Primosomal protein DnaI
OFKINFCL_02973 7.7e-266 dnaB L Membrane attachment protein
OFKINFCL_02974 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OFKINFCL_02975 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OFKINFCL_02976 1.4e-192 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OFKINFCL_02977 9.9e-67 ytcD K Transcriptional regulator
OFKINFCL_02978 3.6e-200 ytbD EGP Major facilitator Superfamily
OFKINFCL_02979 8.9e-161 ytbE S reductase
OFKINFCL_02980 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OFKINFCL_02981 1.1e-107 ytaF P Probably functions as a manganese efflux pump
OFKINFCL_02982 3.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OFKINFCL_02983 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OFKINFCL_02984 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
OFKINFCL_02985 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFKINFCL_02986 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
OFKINFCL_02987 1.8e-242 icd 1.1.1.42 C isocitrate
OFKINFCL_02988 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
OFKINFCL_02989 2.3e-70 yeaL S membrane
OFKINFCL_02990 2.6e-192 ytvI S sporulation integral membrane protein YtvI
OFKINFCL_02991 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
OFKINFCL_02992 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OFKINFCL_02993 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OFKINFCL_02994 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
OFKINFCL_02995 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OFKINFCL_02996 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
OFKINFCL_02997 0.0 dnaE 2.7.7.7 L DNA polymerase
OFKINFCL_02998 3.2e-56 ytrH S Sporulation protein YtrH
OFKINFCL_02999 8.2e-69 ytrI
OFKINFCL_03000 9.2e-29
OFKINFCL_03001 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
OFKINFCL_03002 2.4e-47 ytpI S YtpI-like protein
OFKINFCL_03003 8e-241 ytoI K transcriptional regulator containing CBS domains
OFKINFCL_03004 1.4e-156 ytnM S membrane transporter protein
OFKINFCL_03005 2.8e-235 ytnL 3.5.1.47 E hydrolase activity
OFKINFCL_03006 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
OFKINFCL_03007 5.7e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFKINFCL_03008 2.1e-45 ytnI O COG0695 Glutaredoxin and related proteins
OFKINFCL_03009 4e-184 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFKINFCL_03010 2.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OFKINFCL_03011 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
OFKINFCL_03012 1.6e-121 tcyL P Binding-protein-dependent transport system inner membrane component
OFKINFCL_03013 6.4e-148 tcyK M Bacterial periplasmic substrate-binding proteins
OFKINFCL_03014 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
OFKINFCL_03015 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
OFKINFCL_03016 3.6e-171 ytlI K LysR substrate binding domain
OFKINFCL_03017 1.7e-130 ytkL S Belongs to the UPF0173 family
OFKINFCL_03018 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFKINFCL_03020 8.3e-265 argH 4.3.2.1 E argininosuccinate lyase
OFKINFCL_03021 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
OFKINFCL_03022 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
OFKINFCL_03023 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OFKINFCL_03024 7e-165 ytxK 2.1.1.72 L DNA methylase
OFKINFCL_03025 7.1e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OFKINFCL_03026 2.3e-70 ytfJ S Sporulation protein YtfJ
OFKINFCL_03027 5.6e-116 ytfI S Protein of unknown function (DUF2953)
OFKINFCL_03028 8.5e-87 yteJ S RDD family
OFKINFCL_03029 3.5e-180 sppA OU signal peptide peptidase SppA
OFKINFCL_03030 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OFKINFCL_03031 0.0 ytcJ S amidohydrolase
OFKINFCL_03032 5.5e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OFKINFCL_03033 2e-29 sspB S spore protein
OFKINFCL_03034 1.7e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OFKINFCL_03035 2.3e-207 iscS2 2.8.1.7 E Cysteine desulfurase
OFKINFCL_03036 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
OFKINFCL_03037 1.2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OFKINFCL_03038 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
OFKINFCL_03039 1e-108 yttP K Transcriptional regulator
OFKINFCL_03040 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
OFKINFCL_03041 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
OFKINFCL_03042 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OFKINFCL_03044 8e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OFKINFCL_03045 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OFKINFCL_03046 1.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
OFKINFCL_03047 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
OFKINFCL_03048 5.4e-225 acuC BQ histone deacetylase
OFKINFCL_03049 1.4e-125 motS N Flagellar motor protein
OFKINFCL_03050 2.1e-146 motA N flagellar motor
OFKINFCL_03051 1.7e-182 ccpA K catabolite control protein A
OFKINFCL_03052 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
OFKINFCL_03053 3.1e-53 ytxJ O Protein of unknown function (DUF2847)
OFKINFCL_03054 6.6e-17 ytxH S COG4980 Gas vesicle protein
OFKINFCL_03055 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OFKINFCL_03056 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OFKINFCL_03057 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
OFKINFCL_03058 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OFKINFCL_03059 3.7e-148 ytpQ S Belongs to the UPF0354 family
OFKINFCL_03060 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OFKINFCL_03061 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
OFKINFCL_03062 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
OFKINFCL_03063 1.1e-50 ytzB S small secreted protein
OFKINFCL_03064 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
OFKINFCL_03065 9.3e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
OFKINFCL_03066 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OFKINFCL_03067 2e-45 ytzH S YtzH-like protein
OFKINFCL_03068 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
OFKINFCL_03069 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
OFKINFCL_03070 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
OFKINFCL_03071 8.5e-165 ytlQ
OFKINFCL_03072 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OFKINFCL_03073 2.5e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OFKINFCL_03074 3e-270 pepV 3.5.1.18 E Dipeptidase
OFKINFCL_03075 1.3e-224 pbuO S permease
OFKINFCL_03076 4.2e-201 ythQ U Bacterial ABC transporter protein EcsB
OFKINFCL_03077 1.4e-130 ythP V ABC transporter
OFKINFCL_03078 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
OFKINFCL_03079 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OFKINFCL_03080 2.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OFKINFCL_03081 1.4e-231 ytfP S HI0933-like protein
OFKINFCL_03082 2.2e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
OFKINFCL_03083 3.1e-26 yteV S Sporulation protein Cse60
OFKINFCL_03084 7.7e-115 yteU S Integral membrane protein
OFKINFCL_03085 3.9e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
OFKINFCL_03086 1.3e-72 yteS G transport
OFKINFCL_03087 1.6e-218 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
OFKINFCL_03088 5.8e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
OFKINFCL_03089 0.0 ytdP K Transcriptional regulator
OFKINFCL_03090 1.8e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
OFKINFCL_03091 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
OFKINFCL_03092 5.3e-136 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
OFKINFCL_03093 9.5e-217 bioI 1.14.14.46 C Cytochrome P450
OFKINFCL_03094 6.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OFKINFCL_03095 1.3e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OFKINFCL_03096 8.7e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OFKINFCL_03097 1.1e-256 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
OFKINFCL_03098 2e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
OFKINFCL_03099 1.1e-172 ytaP S Acetyl xylan esterase (AXE1)
OFKINFCL_03100 4.3e-189 msmR K Transcriptional regulator
OFKINFCL_03101 1.5e-244 msmE G Bacterial extracellular solute-binding protein
OFKINFCL_03102 6.2e-168 amyD P ABC transporter
OFKINFCL_03103 1.1e-142 amyC P ABC transporter (permease)
OFKINFCL_03104 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
OFKINFCL_03105 8.1e-51 ytwF P Sulfurtransferase
OFKINFCL_03106 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OFKINFCL_03107 7.7e-55 ytvB S Protein of unknown function (DUF4257)
OFKINFCL_03108 5.1e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
OFKINFCL_03109 1.3e-210 yttB EGP Major facilitator Superfamily
OFKINFCL_03110 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
OFKINFCL_03111 0.0 bceB V ABC transporter (permease)
OFKINFCL_03112 1.1e-138 bceA V ABC transporter, ATP-binding protein
OFKINFCL_03113 1.2e-185 T PhoQ Sensor
OFKINFCL_03114 2.6e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFKINFCL_03115 5.5e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
OFKINFCL_03116 9.1e-127 ytrE V ABC transporter, ATP-binding protein
OFKINFCL_03117 1.3e-147
OFKINFCL_03118 4.7e-153 P ABC-2 family transporter protein
OFKINFCL_03119 2.7e-160 ytrB P abc transporter atp-binding protein
OFKINFCL_03120 5.1e-66 ytrA K GntR family transcriptional regulator
OFKINFCL_03122 6.7e-41 ytzC S Protein of unknown function (DUF2524)
OFKINFCL_03123 8.1e-190 yhcC S Fe-S oxidoreductase
OFKINFCL_03124 1.2e-103 ytqB J Putative rRNA methylase
OFKINFCL_03125 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
OFKINFCL_03126 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
OFKINFCL_03127 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OFKINFCL_03128 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
OFKINFCL_03129 0.0 asnB 6.3.5.4 E Asparagine synthase
OFKINFCL_03130 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OFKINFCL_03131 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OFKINFCL_03132 1.2e-38 ytmB S Protein of unknown function (DUF2584)
OFKINFCL_03133 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
OFKINFCL_03134 1.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OFKINFCL_03135 1.4e-144 ytlC P ABC transporter
OFKINFCL_03136 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OFKINFCL_03137 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
OFKINFCL_03138 5.4e-63 ytkC S Bacteriophage holin family
OFKINFCL_03139 2.1e-76 dps P Belongs to the Dps family
OFKINFCL_03141 2.4e-72 ytkA S YtkA-like
OFKINFCL_03142 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OFKINFCL_03143 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OFKINFCL_03144 3.6e-41 rpmE2 J Ribosomal protein L31
OFKINFCL_03145 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
OFKINFCL_03146 1.6e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
OFKINFCL_03147 1.1e-24 S Domain of Unknown Function (DUF1540)
OFKINFCL_03148 9.7e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
OFKINFCL_03149 9.7e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OFKINFCL_03150 3.3e-138 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OFKINFCL_03151 6.7e-170 troA P Belongs to the bacterial solute-binding protein 9 family
OFKINFCL_03152 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
OFKINFCL_03153 8.8e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OFKINFCL_03154 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OFKINFCL_03155 3.3e-152 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
OFKINFCL_03156 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OFKINFCL_03157 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
OFKINFCL_03158 5.7e-132 dksA T COG1734 DnaK suppressor protein
OFKINFCL_03159 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
OFKINFCL_03160 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OFKINFCL_03161 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
OFKINFCL_03162 1.4e-234 ytcC M Glycosyltransferase Family 4
OFKINFCL_03164 6.3e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
OFKINFCL_03165 2e-216 cotSA M Glycosyl transferases group 1
OFKINFCL_03166 3.7e-204 cotI S Spore coat protein
OFKINFCL_03167 4.9e-76 tspO T membrane
OFKINFCL_03168 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
OFKINFCL_03169 1.2e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
OFKINFCL_03170 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
OFKINFCL_03171 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OFKINFCL_03172 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OFKINFCL_03181 7.8e-08
OFKINFCL_03189 2e-08
OFKINFCL_03194 3.4e-39 S COG NOG14552 non supervised orthologous group
OFKINFCL_03195 5e-86 thiT S Thiamine transporter protein (Thia_YuaJ)
OFKINFCL_03196 6.4e-93 M1-753 M FR47-like protein
OFKINFCL_03197 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
OFKINFCL_03198 1e-74 yuaF OU Membrane protein implicated in regulation of membrane protease activity
OFKINFCL_03199 3.9e-84 yuaE S DinB superfamily
OFKINFCL_03200 2.3e-107 yuaD
OFKINFCL_03201 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
OFKINFCL_03202 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
OFKINFCL_03203 1.4e-95 yuaC K Belongs to the GbsR family
OFKINFCL_03204 2.2e-91 yuaB
OFKINFCL_03205 3.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
OFKINFCL_03206 9.6e-234 ktrB P Potassium
OFKINFCL_03207 1e-38 yiaA S yiaA/B two helix domain
OFKINFCL_03208 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OFKINFCL_03209 2.4e-273 yubD P Major Facilitator Superfamily
OFKINFCL_03210 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
OFKINFCL_03212 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
OFKINFCL_03213 6.3e-197 yubA S transporter activity
OFKINFCL_03214 9.7e-183 ygjR S Oxidoreductase
OFKINFCL_03215 4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
OFKINFCL_03216 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
OFKINFCL_03217 6.7e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
OFKINFCL_03218 5e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
OFKINFCL_03219 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
OFKINFCL_03220 7.3e-238 mcpA NT chemotaxis protein
OFKINFCL_03221 1.4e-294 mcpA NT chemotaxis protein
OFKINFCL_03222 1.1e-220 mcpA NT chemotaxis protein
OFKINFCL_03223 9.3e-225 mcpA NT chemotaxis protein
OFKINFCL_03224 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
OFKINFCL_03225 1e-35
OFKINFCL_03226 2.1e-72 yugU S Uncharacterised protein family UPF0047
OFKINFCL_03227 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
OFKINFCL_03228 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
OFKINFCL_03229 1.4e-116 yugP S Zn-dependent protease
OFKINFCL_03230 2.3e-38
OFKINFCL_03231 1.1e-53 mstX S Membrane-integrating protein Mistic
OFKINFCL_03232 2.2e-182 yugO P COG1226 Kef-type K transport systems
OFKINFCL_03233 1.4e-71 yugN S YugN-like family
OFKINFCL_03235 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
OFKINFCL_03236 3.1e-228 yugK C Dehydrogenase
OFKINFCL_03237 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
OFKINFCL_03238 1.1e-34 yuzA S Domain of unknown function (DUF378)
OFKINFCL_03239 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
OFKINFCL_03240 9e-198 yugH 2.6.1.1 E Aminotransferase
OFKINFCL_03241 1.6e-85 alaR K Transcriptional regulator
OFKINFCL_03242 4.9e-156 yugF I Hydrolase
OFKINFCL_03243 1.6e-39 yugE S Domain of unknown function (DUF1871)
OFKINFCL_03244 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
OFKINFCL_03245 4.6e-233 T PhoQ Sensor
OFKINFCL_03246 9.7e-70 kapB G Kinase associated protein B
OFKINFCL_03247 1.9e-115 kapD L the KinA pathway to sporulation
OFKINFCL_03249 4.2e-184 yuxJ EGP Major facilitator Superfamily
OFKINFCL_03250 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
OFKINFCL_03251 1.8e-74 yuxK S protein conserved in bacteria
OFKINFCL_03252 6.3e-78 yufK S Family of unknown function (DUF5366)
OFKINFCL_03253 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OFKINFCL_03254 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
OFKINFCL_03255 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
OFKINFCL_03256 3.2e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
OFKINFCL_03257 1.9e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
OFKINFCL_03258 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
OFKINFCL_03259 3.1e-232 maeN C COG3493 Na citrate symporter
OFKINFCL_03260 3.2e-14
OFKINFCL_03261 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OFKINFCL_03262 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OFKINFCL_03263 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OFKINFCL_03264 1.4e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OFKINFCL_03265 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OFKINFCL_03266 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OFKINFCL_03267 2.2e-58 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
OFKINFCL_03268 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
OFKINFCL_03269 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFKINFCL_03270 7.1e-269 comP 2.7.13.3 T Histidine kinase
OFKINFCL_03272 7.5e-140 comQ H Belongs to the FPP GGPP synthase family
OFKINFCL_03274 3.8e-23 yuzC
OFKINFCL_03275 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
OFKINFCL_03276 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OFKINFCL_03277 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
OFKINFCL_03278 1.8e-66 yueI S Protein of unknown function (DUF1694)
OFKINFCL_03279 7.4e-39 yueH S YueH-like protein
OFKINFCL_03280 6.6e-31 yueG S Spore germination protein gerPA/gerPF
OFKINFCL_03281 7.1e-190 yueF S transporter activity
OFKINFCL_03282 1.3e-69 S Protein of unknown function (DUF2283)
OFKINFCL_03283 2.9e-24 S Protein of unknown function (DUF2642)
OFKINFCL_03284 1.4e-95 yueE S phosphohydrolase
OFKINFCL_03285 4.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFKINFCL_03286 5.6e-64 yueC S Family of unknown function (DUF5383)
OFKINFCL_03287 0.0 esaA S type VII secretion protein EsaA
OFKINFCL_03288 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OFKINFCL_03289 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
OFKINFCL_03290 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
OFKINFCL_03291 2.8e-45 esxA S Belongs to the WXG100 family
OFKINFCL_03292 2.8e-227 yukF QT Transcriptional regulator
OFKINFCL_03293 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
OFKINFCL_03294 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
OFKINFCL_03295 8.5e-36 mbtH S MbtH-like protein
OFKINFCL_03296 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFKINFCL_03297 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
OFKINFCL_03298 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
OFKINFCL_03299 4.3e-225 entC 5.4.4.2 HQ Isochorismate synthase
OFKINFCL_03300 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OFKINFCL_03301 1.5e-166 besA S Putative esterase
OFKINFCL_03302 1.7e-121 yuiH S Oxidoreductase molybdopterin binding domain
OFKINFCL_03303 5.7e-93 bioY S Biotin biosynthesis protein
OFKINFCL_03304 3.9e-211 yuiF S antiporter
OFKINFCL_03305 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OFKINFCL_03306 1.2e-77 yuiD S protein conserved in bacteria
OFKINFCL_03307 1.4e-116 yuiC S protein conserved in bacteria
OFKINFCL_03308 8.4e-27 yuiB S Putative membrane protein
OFKINFCL_03309 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
OFKINFCL_03310 3.9e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
OFKINFCL_03312 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OFKINFCL_03313 3.8e-116 paiB K Putative FMN-binding domain
OFKINFCL_03314 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFKINFCL_03315 3.7e-63 erpA S Belongs to the HesB IscA family
OFKINFCL_03316 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OFKINFCL_03317 1.2e-198 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OFKINFCL_03318 3.2e-39 yuzB S Belongs to the UPF0349 family
OFKINFCL_03319 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
OFKINFCL_03320 3.5e-57 yuzD S protein conserved in bacteria
OFKINFCL_03321 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
OFKINFCL_03322 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
OFKINFCL_03323 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OFKINFCL_03324 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OFKINFCL_03325 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
OFKINFCL_03326 2.9e-198 yutH S Spore coat protein
OFKINFCL_03327 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OFKINFCL_03328 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OFKINFCL_03329 1e-75 yutE S Protein of unknown function DUF86
OFKINFCL_03330 9.7e-48 yutD S protein conserved in bacteria
OFKINFCL_03331 1.1e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OFKINFCL_03332 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OFKINFCL_03333 4.5e-196 lytH M Peptidase, M23
OFKINFCL_03334 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
OFKINFCL_03335 3.1e-47 yunC S Domain of unknown function (DUF1805)
OFKINFCL_03336 1.6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OFKINFCL_03337 1e-140 yunE S membrane transporter protein
OFKINFCL_03338 4.3e-171 yunF S Protein of unknown function DUF72
OFKINFCL_03339 2.8e-60 yunG
OFKINFCL_03340 2.4e-256 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
OFKINFCL_03341 3.2e-300 pucR QT COG2508 Regulator of polyketide synthase expression
OFKINFCL_03342 3.7e-233 pbuX F Permease family
OFKINFCL_03343 8.7e-224 pbuX F xanthine
OFKINFCL_03344 1.8e-281 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
OFKINFCL_03345 2.1e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
OFKINFCL_03346 1.4e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
OFKINFCL_03347 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
OFKINFCL_03348 5.7e-144 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
OFKINFCL_03349 1.2e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
OFKINFCL_03350 4.1e-189 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OFKINFCL_03351 8.7e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
OFKINFCL_03352 7e-231 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OFKINFCL_03353 3.5e-168 bsn L Ribonuclease
OFKINFCL_03354 1.7e-204 msmX P Belongs to the ABC transporter superfamily
OFKINFCL_03355 3.3e-135 yurK K UTRA
OFKINFCL_03356 3.3e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
OFKINFCL_03357 5.2e-167 yurM P COG0395 ABC-type sugar transport system, permease component
OFKINFCL_03358 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
OFKINFCL_03359 7.2e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
OFKINFCL_03360 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
OFKINFCL_03361 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
OFKINFCL_03362 6.4e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
OFKINFCL_03364 1.5e-40
OFKINFCL_03365 6.6e-156
OFKINFCL_03367 7.3e-61 yfmQ S Uncharacterised protein from bacillus cereus group
OFKINFCL_03369 3.6e-109 S aspartate phosphatase
OFKINFCL_03370 2.5e-266 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OFKINFCL_03371 4.8e-52 S SMI1-KNR4 cell-wall
OFKINFCL_03372 6.1e-129 xlyB 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
OFKINFCL_03373 4.2e-58 S Bacteriophage holin family
OFKINFCL_03375 3.4e-08
OFKINFCL_03376 4e-86
OFKINFCL_03377 1.8e-60
OFKINFCL_03378 3.2e-102 mur1 NU Prophage endopeptidase tail
OFKINFCL_03379 2e-43 S Phage tail protein
OFKINFCL_03380 6.8e-148 D Phage-related minor tail protein
OFKINFCL_03382 1.8e-52 S phage major tail protein, phi13 family
OFKINFCL_03383 1.9e-17
OFKINFCL_03384 9.5e-15 S Bacteriophage HK97-gp10, putative tail-component
OFKINFCL_03385 2.1e-07 S head-tail adaptor
OFKINFCL_03386 1.3e-10 S Phage gp6-like head-tail connector protein
OFKINFCL_03387 8.1e-89 S Phage capsid family
OFKINFCL_03388 1.9e-48 S Caudovirus prohead serine protease
OFKINFCL_03389 2.5e-105 S Phage portal protein
OFKINFCL_03390 1.1e-149 S Phage Terminase
OFKINFCL_03391 3.1e-18
OFKINFCL_03392 3.9e-28 L HNH endonuclease
OFKINFCL_03394 4.9e-11
OFKINFCL_03395 4.1e-51 wecC 1.1.1.336 M ArpU family transcriptional regulator
OFKINFCL_03396 4e-19 S Phage-like element PBSX protein XtrA
OFKINFCL_03397 3.2e-22
OFKINFCL_03398 4.4e-170 dnaB 3.6.4.12 L replicative DNA helicase
OFKINFCL_03399 7.2e-27 S Loader and inhibitor of phage G40P
OFKINFCL_03400 4.4e-98 L DnaD domain protein
OFKINFCL_03402 3.4e-11
OFKINFCL_03403 3.2e-81 S Phage regulatory protein Rha (Phage_pRha)
OFKINFCL_03407 3.6e-23
OFKINFCL_03409 8.3e-26 K Helix-turn-helix XRE-family like proteins
OFKINFCL_03410 2.5e-43 E Zn peptidase
OFKINFCL_03411 5.2e-151 S Pfam:Arm-DNA-bind_4
OFKINFCL_03412 1e-270 sufB O FeS cluster assembly
OFKINFCL_03413 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
OFKINFCL_03414 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OFKINFCL_03415 1.4e-245 sufD O assembly protein SufD
OFKINFCL_03416 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
OFKINFCL_03417 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OFKINFCL_03418 9.4e-147 metQ P Belongs to the NlpA lipoprotein family
OFKINFCL_03419 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
OFKINFCL_03420 1.8e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OFKINFCL_03421 2.4e-56 yusD S SCP-2 sterol transfer family
OFKINFCL_03422 5.6e-55 traF CO Thioredoxin
OFKINFCL_03423 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
OFKINFCL_03424 1.1e-39 yusG S Protein of unknown function (DUF2553)
OFKINFCL_03425 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
OFKINFCL_03426 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
OFKINFCL_03427 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
OFKINFCL_03428 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
OFKINFCL_03429 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
OFKINFCL_03430 8.1e-09 S YuzL-like protein
OFKINFCL_03431 7.1e-164 fadM E Proline dehydrogenase
OFKINFCL_03432 5.1e-40
OFKINFCL_03433 9.3e-53 yusN M Coat F domain
OFKINFCL_03434 6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
OFKINFCL_03435 8.5e-293 yusP P Major facilitator superfamily
OFKINFCL_03436 2.1e-64 yusQ S Tautomerase enzyme
OFKINFCL_03437 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OFKINFCL_03438 5.7e-158 yusT K LysR substrate binding domain
OFKINFCL_03439 1.1e-46 yusU S Protein of unknown function (DUF2573)
OFKINFCL_03440 3.9e-153 yusV 3.6.3.34 HP ABC transporter
OFKINFCL_03441 2.5e-66 S YusW-like protein
OFKINFCL_03442 2.7e-300 pepF2 E COG1164 Oligoendopeptidase F
OFKINFCL_03443 5.2e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OFKINFCL_03444 4.7e-79 dps P Ferritin-like domain
OFKINFCL_03445 7.8e-231 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OFKINFCL_03446 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFKINFCL_03447 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
OFKINFCL_03448 4.3e-158 yuxN K Transcriptional regulator
OFKINFCL_03449 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OFKINFCL_03450 2.3e-24 S Protein of unknown function (DUF3970)
OFKINFCL_03451 3.1e-246 gerAA EG Spore germination protein
OFKINFCL_03452 3.8e-196 gerAB E Spore germination protein
OFKINFCL_03453 3.6e-181 gerAC S Spore germination B3/ GerAC like, C-terminal
OFKINFCL_03454 7.3e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFKINFCL_03455 1.1e-184 vraS 2.7.13.3 T Histidine kinase
OFKINFCL_03456 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
OFKINFCL_03457 8.7e-127 liaG S Putative adhesin
OFKINFCL_03458 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
OFKINFCL_03459 5.6e-62 liaI S membrane
OFKINFCL_03460 5.9e-225 yvqJ EGP Major facilitator Superfamily
OFKINFCL_03461 9.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
OFKINFCL_03462 8.6e-243 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
OFKINFCL_03463 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFKINFCL_03464 5.5e-167 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
OFKINFCL_03465 1.2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OFKINFCL_03466 6.9e-138 yvrE G SMP-30/Gluconolaconase/LRE-like region
OFKINFCL_03467 5e-17 yvrE G SMP-30/Gluconolaconase/LRE-like region
OFKINFCL_03468 0.0 T PhoQ Sensor
OFKINFCL_03469 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFKINFCL_03470 3.6e-22
OFKINFCL_03471 1.6e-97 yvrI K RNA polymerase
OFKINFCL_03472 2.4e-19 S YvrJ protein family
OFKINFCL_03473 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
OFKINFCL_03474 1.3e-64 yvrL S Regulatory protein YrvL
OFKINFCL_03475 4.5e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
OFKINFCL_03476 1.6e-123 macB V ABC transporter, ATP-binding protein
OFKINFCL_03477 1.7e-173 M Efflux transporter rnd family, mfp subunit
OFKINFCL_03478 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
OFKINFCL_03479 9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFKINFCL_03480 1.8e-182 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFKINFCL_03481 1.4e-178 fhuD P ABC transporter
OFKINFCL_03483 4.9e-236 yvsH E Arginine ornithine antiporter
OFKINFCL_03484 6.5e-16 S Small spore protein J (Spore_SspJ)
OFKINFCL_03485 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
OFKINFCL_03486 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OFKINFCL_03487 2.9e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
OFKINFCL_03488 4.9e-137 modA P COG0725 ABC-type molybdate transport system, periplasmic component
OFKINFCL_03489 9e-119 modB P COG4149 ABC-type molybdate transport system, permease component
OFKINFCL_03490 1.7e-156 yvgN S reductase
OFKINFCL_03491 5.4e-86 yvgO
OFKINFCL_03492 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
OFKINFCL_03493 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
OFKINFCL_03494 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OFKINFCL_03495 0.0 helD 3.6.4.12 L DNA helicase
OFKINFCL_03497 1.6e-106 yvgT S membrane
OFKINFCL_03498 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
OFKINFCL_03499 2.7e-104 bdbD O Thioredoxin
OFKINFCL_03500 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OFKINFCL_03501 0.0 copA 3.6.3.54 P P-type ATPase
OFKINFCL_03502 1.5e-29 copZ P Copper resistance protein CopZ
OFKINFCL_03503 2.2e-48 csoR S transcriptional
OFKINFCL_03504 1.2e-194 yvaA 1.1.1.371 S Oxidoreductase
OFKINFCL_03505 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OFKINFCL_03506 0.0 yvaC S Fusaric acid resistance protein-like
OFKINFCL_03507 5.7e-73 yvaD S Family of unknown function (DUF5360)
OFKINFCL_03508 2e-53 yvaE P Small Multidrug Resistance protein
OFKINFCL_03509 1.3e-99 K Bacterial regulatory proteins, tetR family
OFKINFCL_03510 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OFKINFCL_03512 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OFKINFCL_03513 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OFKINFCL_03514 5.6e-143 est 3.1.1.1 S Carboxylesterase
OFKINFCL_03515 2.4e-23 secG U Preprotein translocase subunit SecG
OFKINFCL_03516 5.9e-151 yvaM S Serine aminopeptidase, S33
OFKINFCL_03517 7.5e-36 yvzC K Transcriptional
OFKINFCL_03518 4e-69 K transcriptional
OFKINFCL_03519 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
OFKINFCL_03520 2.2e-54 yodB K transcriptional
OFKINFCL_03521 6.7e-224 NT chemotaxis protein
OFKINFCL_03522 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OFKINFCL_03523 2.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OFKINFCL_03524 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OFKINFCL_03525 5.7e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OFKINFCL_03526 7.4e-60 yvbF K Belongs to the GbsR family
OFKINFCL_03527 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OFKINFCL_03528 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OFKINFCL_03529 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OFKINFCL_03530 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OFKINFCL_03531 1.4e-98 yvbF K Belongs to the GbsR family
OFKINFCL_03532 1.9e-102 yvbG U UPF0056 membrane protein
OFKINFCL_03533 8.6e-113 yvbH S YvbH-like oligomerisation region
OFKINFCL_03534 3.6e-123 exoY M Membrane
OFKINFCL_03535 0.0 tcaA S response to antibiotic
OFKINFCL_03536 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
OFKINFCL_03537 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OFKINFCL_03538 3.7e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
OFKINFCL_03539 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OFKINFCL_03540 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OFKINFCL_03541 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OFKINFCL_03542 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OFKINFCL_03543 1.6e-252 araE EGP Major facilitator Superfamily
OFKINFCL_03544 5.5e-203 araR K transcriptional
OFKINFCL_03545 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFKINFCL_03546 3.9e-159 yvbU K Transcriptional regulator
OFKINFCL_03547 1.6e-155 yvbV EG EamA-like transporter family
OFKINFCL_03548 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
OFKINFCL_03549 2.9e-193 yvbX S Glycosyl hydrolase
OFKINFCL_03550 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OFKINFCL_03551 1.1e-272 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
OFKINFCL_03552 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OFKINFCL_03553 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFKINFCL_03554 2.1e-197 desK 2.7.13.3 T Histidine kinase
OFKINFCL_03555 1.8e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
OFKINFCL_03556 8.6e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
OFKINFCL_03557 2.6e-157 rsbQ S Alpha/beta hydrolase family
OFKINFCL_03558 7.7e-198 rsbU 3.1.3.3 T response regulator
OFKINFCL_03559 3e-248 galA 3.2.1.89 G arabinogalactan
OFKINFCL_03560 0.0 lacA 3.2.1.23 G beta-galactosidase
OFKINFCL_03561 7.2e-150 ganQ P transport
OFKINFCL_03562 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
OFKINFCL_03563 2.6e-225 cycB G COG2182 Maltose-binding periplasmic proteins domains
OFKINFCL_03564 5.2e-184 lacR K Transcriptional regulator
OFKINFCL_03565 1e-112 yvfI K COG2186 Transcriptional regulators
OFKINFCL_03566 5.7e-308 yvfH C L-lactate permease
OFKINFCL_03567 1.4e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
OFKINFCL_03568 1e-31 yvfG S YvfG protein
OFKINFCL_03569 1.7e-187 yvfF GM Exopolysaccharide biosynthesis protein
OFKINFCL_03570 6.2e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OFKINFCL_03571 9e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
OFKINFCL_03572 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OFKINFCL_03573 2.8e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OFKINFCL_03574 1.4e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
OFKINFCL_03575 3.7e-204 epsI GM pyruvyl transferase
OFKINFCL_03576 2e-194 epsH GT2 S Glycosyltransferase like family 2
OFKINFCL_03577 4.1e-206 epsG S EpsG family
OFKINFCL_03578 1.2e-216 epsF GT4 M Glycosyl transferases group 1
OFKINFCL_03579 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OFKINFCL_03580 2.7e-221 epsD GT4 M Glycosyl transferase 4-like
OFKINFCL_03581 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
OFKINFCL_03582 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
OFKINFCL_03583 1.5e-121 ywqC M biosynthesis protein
OFKINFCL_03584 2.8e-76 slr K transcriptional
OFKINFCL_03585 1.6e-285 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
OFKINFCL_03587 1.7e-92 padC Q Phenolic acid decarboxylase
OFKINFCL_03588 9.5e-46 MA20_18690 S Protein of unknown function (DUF3237)
OFKINFCL_03589 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
OFKINFCL_03590 3.2e-261 pbpE V Beta-lactamase
OFKINFCL_03591 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
OFKINFCL_03592 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
OFKINFCL_03593 3.9e-295 yveA E amino acid
OFKINFCL_03594 7.4e-106 yvdT K Transcriptional regulator
OFKINFCL_03595 1.5e-50 ykkC P Small Multidrug Resistance protein
OFKINFCL_03596 4.1e-50 sugE P Small Multidrug Resistance protein
OFKINFCL_03597 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
OFKINFCL_03598 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
OFKINFCL_03599 1.2e-182 S Patatin-like phospholipase
OFKINFCL_03601 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OFKINFCL_03602 2.8e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
OFKINFCL_03603 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
OFKINFCL_03604 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
OFKINFCL_03605 9.1e-156 malA S Protein of unknown function (DUF1189)
OFKINFCL_03606 3.9e-148 malD P transport
OFKINFCL_03607 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
OFKINFCL_03608 3.1e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
OFKINFCL_03609 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
OFKINFCL_03610 3.3e-172 yvdE K Transcriptional regulator
OFKINFCL_03611 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
OFKINFCL_03612 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
OFKINFCL_03613 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
OFKINFCL_03614 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OFKINFCL_03615 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OFKINFCL_03616 0.0 yxdM V ABC transporter (permease)
OFKINFCL_03617 5.6e-141 yvcR V ABC transporter, ATP-binding protein
OFKINFCL_03618 3.1e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
OFKINFCL_03619 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFKINFCL_03620 1.8e-33
OFKINFCL_03621 2.3e-139 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
OFKINFCL_03622 1.6e-36 crh G Phosphocarrier protein Chr
OFKINFCL_03623 1.4e-170 whiA K May be required for sporulation
OFKINFCL_03624 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OFKINFCL_03625 5.7e-166 rapZ S Displays ATPase and GTPase activities
OFKINFCL_03626 1.5e-86 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OFKINFCL_03627 3.2e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OFKINFCL_03628 1.8e-97 usp CBM50 M protein conserved in bacteria
OFKINFCL_03629 2.4e-278 S COG0457 FOG TPR repeat
OFKINFCL_03630 0.0 msbA2 3.6.3.44 V ABC transporter
OFKINFCL_03632 0.0
OFKINFCL_03633 4.9e-75
OFKINFCL_03634 4.6e-16
OFKINFCL_03635 3e-22
OFKINFCL_03637 5.3e-69
OFKINFCL_03638 3.7e-94 Otg1 S Predicted membrane protein (DUF2339)
OFKINFCL_03639 7.4e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
OFKINFCL_03640 4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
OFKINFCL_03641 2e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OFKINFCL_03642 6.9e-113 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OFKINFCL_03643 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
OFKINFCL_03644 4.4e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OFKINFCL_03645 6.2e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
OFKINFCL_03646 1.5e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OFKINFCL_03647 1.1e-138 yvpB NU protein conserved in bacteria
OFKINFCL_03648 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
OFKINFCL_03649 7.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
OFKINFCL_03650 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
OFKINFCL_03651 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
OFKINFCL_03652 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OFKINFCL_03653 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OFKINFCL_03654 7.8e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OFKINFCL_03655 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OFKINFCL_03656 3.6e-134 yvoA K transcriptional
OFKINFCL_03657 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
OFKINFCL_03658 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
OFKINFCL_03659 4.1e-231 cypX 1.14.15.13 C Cytochrome P450
OFKINFCL_03660 3.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
OFKINFCL_03661 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
OFKINFCL_03662 2.7e-203 yvmA EGP Major facilitator Superfamily
OFKINFCL_03663 1.2e-50 yvlD S Membrane
OFKINFCL_03664 4.4e-26 pspB KT PspC domain
OFKINFCL_03665 9.8e-168 yvlB S Putative adhesin
OFKINFCL_03666 8e-49 yvlA
OFKINFCL_03667 5.7e-33 yvkN
OFKINFCL_03668 8.7e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OFKINFCL_03669 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OFKINFCL_03670 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OFKINFCL_03671 1.2e-30 csbA S protein conserved in bacteria
OFKINFCL_03672 0.0 yvkC 2.7.9.2 GT Phosphotransferase
OFKINFCL_03673 7e-101 yvkB K Transcriptional regulator
OFKINFCL_03674 2.8e-225 yvkA EGP Major facilitator Superfamily
OFKINFCL_03675 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OFKINFCL_03676 5.3e-56 swrA S Swarming motility protein
OFKINFCL_03677 4.5e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
OFKINFCL_03678 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
OFKINFCL_03679 1.6e-123 ftsE D cell division ATP-binding protein FtsE
OFKINFCL_03680 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
OFKINFCL_03681 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
OFKINFCL_03682 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OFKINFCL_03683 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OFKINFCL_03684 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OFKINFCL_03685 1.8e-65
OFKINFCL_03686 2.5e-08 fliT S bacterial-type flagellum organization
OFKINFCL_03687 2.9e-69 fliS N flagellar protein FliS
OFKINFCL_03688 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OFKINFCL_03689 1.2e-55 flaG N flagellar protein FlaG
OFKINFCL_03690 7.1e-110 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OFKINFCL_03691 5.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OFKINFCL_03692 8e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OFKINFCL_03693 5.7e-50 yviE
OFKINFCL_03694 7.8e-155 flgL N Belongs to the bacterial flagellin family
OFKINFCL_03695 1.2e-264 flgK N flagellar hook-associated protein
OFKINFCL_03696 1.6e-77 flgN NOU FlgN protein
OFKINFCL_03697 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
OFKINFCL_03698 7e-74 yvyF S flagellar protein
OFKINFCL_03699 1.2e-126 comFC S Phosphoribosyl transferase domain
OFKINFCL_03700 1.1e-44 comFB S Late competence development protein ComFB
OFKINFCL_03701 4.9e-265 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OFKINFCL_03702 7.3e-155 degV S protein conserved in bacteria
OFKINFCL_03703 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFKINFCL_03704 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
OFKINFCL_03705 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
OFKINFCL_03706 6e-163 yvhJ K Transcriptional regulator
OFKINFCL_03707 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
OFKINFCL_03708 6e-235 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
OFKINFCL_03709 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
OFKINFCL_03710 1.2e-112 tuaF M protein involved in exopolysaccharide biosynthesis
OFKINFCL_03711 1.3e-252 tuaE M Teichuronic acid biosynthesis protein
OFKINFCL_03712 1.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OFKINFCL_03713 1.7e-218 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
OFKINFCL_03714 1.7e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OFKINFCL_03715 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OFKINFCL_03716 1.5e-94 M Glycosyltransferase like family 2
OFKINFCL_03717 2.6e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OFKINFCL_03718 0.0 lytB 3.5.1.28 D Stage II sporulation protein
OFKINFCL_03719 1e-11
OFKINFCL_03720 5.9e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OFKINFCL_03721 1e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OFKINFCL_03722 2.1e-88 M Glycosyltransferase like family 2
OFKINFCL_03723 7.1e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
OFKINFCL_03724 1.1e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
OFKINFCL_03725 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OFKINFCL_03726 5.8e-270 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OFKINFCL_03727 1e-132 tagG GM Transport permease protein
OFKINFCL_03728 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
OFKINFCL_03729 9e-240 ggaA M Glycosyltransferase like family 2
OFKINFCL_03730 1.1e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OFKINFCL_03731 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
OFKINFCL_03732 9.2e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OFKINFCL_03733 1.5e-105 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OFKINFCL_03734 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
OFKINFCL_03735 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
OFKINFCL_03736 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
OFKINFCL_03737 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
OFKINFCL_03738 2.8e-216 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OFKINFCL_03739 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
OFKINFCL_03740 3.5e-266 gerBA EG Spore germination protein
OFKINFCL_03741 7.5e-200 gerBB E Spore germination protein
OFKINFCL_03742 7.6e-216 gerAC S Spore germination protein
OFKINFCL_03743 4.1e-248 ywtG EGP Major facilitator Superfamily
OFKINFCL_03744 1.1e-170 ywtF K Transcriptional regulator
OFKINFCL_03745 2.9e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
OFKINFCL_03746 4.5e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OFKINFCL_03747 1.4e-20 ywtC
OFKINFCL_03748 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
OFKINFCL_03749 8.6e-70 pgsC S biosynthesis protein
OFKINFCL_03750 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
OFKINFCL_03751 6.1e-177 rbsR K transcriptional
OFKINFCL_03752 2.7e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OFKINFCL_03753 9e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
OFKINFCL_03754 8.6e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
OFKINFCL_03755 1.8e-152 rbsC G Belongs to the binding-protein-dependent transport system permease family
OFKINFCL_03756 4.5e-158 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
OFKINFCL_03757 5.2e-90 batE T Sh3 type 3 domain protein
OFKINFCL_03758 8e-48 ywsA S Protein of unknown function (DUF3892)
OFKINFCL_03759 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
OFKINFCL_03760 6.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
OFKINFCL_03761 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OFKINFCL_03762 1.1e-169 alsR K LysR substrate binding domain
OFKINFCL_03763 2.5e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OFKINFCL_03764 4.5e-123 ywrJ
OFKINFCL_03765 7.6e-131 cotB
OFKINFCL_03766 6e-210 cotH M Spore Coat
OFKINFCL_03767 3.7e-12
OFKINFCL_03768 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OFKINFCL_03769 1.4e-53 S Domain of unknown function (DUF4181)
OFKINFCL_03770 1.4e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OFKINFCL_03771 8e-82 ywrC K Transcriptional regulator
OFKINFCL_03772 1.2e-103 ywrB P Chromate transporter
OFKINFCL_03773 2.2e-88 ywrA P COG2059 Chromate transport protein ChrA
OFKINFCL_03775 1.1e-100 ywqN S NAD(P)H-dependent
OFKINFCL_03776 4.9e-162 K Transcriptional regulator
OFKINFCL_03777 6.7e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
OFKINFCL_03778 3.9e-25
OFKINFCL_03779 2.7e-242 ywqJ S Pre-toxin TG
OFKINFCL_03780 3.1e-38 ywqI S Family of unknown function (DUF5344)
OFKINFCL_03781 1e-19 S Domain of unknown function (DUF5082)
OFKINFCL_03782 5.4e-152 ywqG S Domain of unknown function (DUF1963)
OFKINFCL_03783 5.2e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OFKINFCL_03784 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
OFKINFCL_03785 2.9e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
OFKINFCL_03786 5.9e-116 ywqC M biosynthesis protein
OFKINFCL_03787 1.2e-17
OFKINFCL_03788 2.1e-307 ywqB S SWIM zinc finger
OFKINFCL_03789 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OFKINFCL_03790 3.9e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
OFKINFCL_03791 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
OFKINFCL_03792 3.7e-57 ssbB L Single-stranded DNA-binding protein
OFKINFCL_03793 3.8e-66 ywpG
OFKINFCL_03794 1.1e-66 ywpF S YwpF-like protein
OFKINFCL_03795 1.8e-84 srtA 3.4.22.70 M Sortase family
OFKINFCL_03796 0.0 M1-568 M cell wall anchor domain
OFKINFCL_03797 5.3e-174 M1-574 T Transcriptional regulatory protein, C terminal
OFKINFCL_03798 0.0 ywpD T PhoQ Sensor
OFKINFCL_03799 1.5e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OFKINFCL_03800 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OFKINFCL_03801 2.3e-198 S aspartate phosphatase
OFKINFCL_03802 3.7e-140 flhP N flagellar basal body
OFKINFCL_03803 3.4e-125 flhO N flagellar basal body
OFKINFCL_03804 3.5e-180 mbl D Rod shape-determining protein
OFKINFCL_03805 3e-44 spoIIID K Stage III sporulation protein D
OFKINFCL_03806 2.1e-70 ywoH K COG1846 Transcriptional regulators
OFKINFCL_03807 2.7e-211 ywoG EGP Major facilitator Superfamily
OFKINFCL_03808 1.4e-230 ywoF P Right handed beta helix region
OFKINFCL_03809 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
OFKINFCL_03810 2.4e-240 ywoD EGP Major facilitator superfamily
OFKINFCL_03811 6.8e-104 phzA Q Isochorismatase family
OFKINFCL_03812 1.7e-76
OFKINFCL_03813 4.3e-225 amt P Ammonium transporter
OFKINFCL_03814 1.6e-58 nrgB K Belongs to the P(II) protein family
OFKINFCL_03815 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
OFKINFCL_03816 1e-72 ywnJ S VanZ like family
OFKINFCL_03817 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
OFKINFCL_03818 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
OFKINFCL_03819 7.5e-09 ywnC S Family of unknown function (DUF5362)
OFKINFCL_03820 2.2e-70 ywnF S Family of unknown function (DUF5392)
OFKINFCL_03821 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OFKINFCL_03822 2.9e-142 mta K transcriptional
OFKINFCL_03823 1.7e-58 ywnC S Family of unknown function (DUF5362)
OFKINFCL_03824 5.8e-112 ywnB S NAD(P)H-binding
OFKINFCL_03825 1.7e-64 ywnA K Transcriptional regulator
OFKINFCL_03826 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
OFKINFCL_03827 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
OFKINFCL_03828 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
OFKINFCL_03829 3.8e-11 csbD K CsbD-like
OFKINFCL_03830 3e-84 ywmF S Peptidase M50
OFKINFCL_03831 7.9e-104 S response regulator aspartate phosphatase
OFKINFCL_03832 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OFKINFCL_03833 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OFKINFCL_03835 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
OFKINFCL_03836 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
OFKINFCL_03837 1e-174 spoIID D Stage II sporulation protein D
OFKINFCL_03838 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OFKINFCL_03839 4.5e-132 ywmB S TATA-box binding
OFKINFCL_03840 1.3e-32 ywzB S membrane
OFKINFCL_03841 4.8e-87 ywmA
OFKINFCL_03842 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OFKINFCL_03843 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OFKINFCL_03844 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OFKINFCL_03845 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OFKINFCL_03846 4.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OFKINFCL_03847 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OFKINFCL_03848 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OFKINFCL_03849 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
OFKINFCL_03850 2.5e-62 atpI S ATP synthase
OFKINFCL_03851 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OFKINFCL_03852 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OFKINFCL_03853 3.6e-94 ywlG S Belongs to the UPF0340 family
OFKINFCL_03854 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
OFKINFCL_03855 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OFKINFCL_03856 1.7e-91 mntP P Probably functions as a manganese efflux pump
OFKINFCL_03857 1.1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OFKINFCL_03858 2.3e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
OFKINFCL_03859 8.4e-109 spoIIR S stage II sporulation protein R
OFKINFCL_03860 4.8e-55 ywlA S Uncharacterised protein family (UPF0715)
OFKINFCL_03862 1.7e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OFKINFCL_03863 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OFKINFCL_03864 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OFKINFCL_03865 2.3e-88 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
OFKINFCL_03866 8.6e-160 ywkB S Membrane transport protein
OFKINFCL_03867 0.0 sfcA 1.1.1.38 C malic enzyme
OFKINFCL_03868 7e-104 tdk 2.7.1.21 F thymidine kinase
OFKINFCL_03869 1.1e-32 rpmE J Binds the 23S rRNA
OFKINFCL_03870 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OFKINFCL_03871 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
OFKINFCL_03872 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OFKINFCL_03873 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OFKINFCL_03874 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
OFKINFCL_03875 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
OFKINFCL_03876 7.9e-91 ywjG S Domain of unknown function (DUF2529)
OFKINFCL_03877 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OFKINFCL_03878 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OFKINFCL_03879 4.4e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
OFKINFCL_03880 0.0 fadF C COG0247 Fe-S oxidoreductase
OFKINFCL_03881 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
OFKINFCL_03882 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
OFKINFCL_03883 2.7e-42 ywjC
OFKINFCL_03884 4.8e-96 ywjB H RibD C-terminal domain
OFKINFCL_03885 0.0 ywjA V ABC transporter
OFKINFCL_03886 1.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OFKINFCL_03887 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
OFKINFCL_03888 6.2e-94 narJ 1.7.5.1 C nitrate reductase
OFKINFCL_03889 1.9e-296 narH 1.7.5.1 C Nitrate reductase, beta
OFKINFCL_03890 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OFKINFCL_03891 7e-86 arfM T cyclic nucleotide binding
OFKINFCL_03892 3.1e-138 ywiC S YwiC-like protein
OFKINFCL_03893 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
OFKINFCL_03894 2.3e-213 narK P COG2223 Nitrate nitrite transporter
OFKINFCL_03895 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OFKINFCL_03896 4.7e-73 ywiB S protein conserved in bacteria
OFKINFCL_03897 1e-07 S Bacteriocin subtilosin A
OFKINFCL_03898 1.3e-270 C Fe-S oxidoreductases
OFKINFCL_03900 3.3e-132 cbiO V ABC transporter
OFKINFCL_03901 7.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
OFKINFCL_03902 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
OFKINFCL_03903 2.3e-248 L Peptidase, M16
OFKINFCL_03905 1.2e-234 ywhL CO amine dehydrogenase activity
OFKINFCL_03906 2.3e-198 ywhK CO amine dehydrogenase activity
OFKINFCL_03907 8.9e-79 S aspartate phosphatase
OFKINFCL_03910 1.7e-20
OFKINFCL_03913 4.1e-57 V ATPases associated with a variety of cellular activities
OFKINFCL_03915 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
OFKINFCL_03916 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OFKINFCL_03917 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OFKINFCL_03918 2e-94 ywhD S YwhD family
OFKINFCL_03919 5.1e-119 ywhC S Peptidase family M50
OFKINFCL_03920 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
OFKINFCL_03921 3.3e-71 ywhA K Transcriptional regulator
OFKINFCL_03922 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OFKINFCL_03924 2.5e-237 mmr U Major Facilitator Superfamily
OFKINFCL_03925 6.2e-79 yffB K Transcriptional regulator
OFKINFCL_03926 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
OFKINFCL_03927 5.1e-256 ywfO S COG1078 HD superfamily phosphohydrolases
OFKINFCL_03928 3.1e-36 ywzC S Belongs to the UPF0741 family
OFKINFCL_03929 1e-110 rsfA_1
OFKINFCL_03930 1.7e-157 ywfM EG EamA-like transporter family
OFKINFCL_03931 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
OFKINFCL_03932 5.4e-156 cysL K Transcriptional regulator
OFKINFCL_03933 1.3e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
OFKINFCL_03934 3.3e-146 ywfI C May function as heme-dependent peroxidase
OFKINFCL_03935 1.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
OFKINFCL_03936 3.3e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
OFKINFCL_03937 1.9e-209 bacE EGP Major facilitator Superfamily
OFKINFCL_03938 6.1e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
OFKINFCL_03939 1.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFKINFCL_03940 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
OFKINFCL_03941 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
OFKINFCL_03942 5.1e-205 ywfA EGP Major facilitator Superfamily
OFKINFCL_03943 5.7e-261 lysP E amino acid
OFKINFCL_03944 0.0 rocB E arginine degradation protein
OFKINFCL_03945 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OFKINFCL_03946 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OFKINFCL_03947 1.2e-77
OFKINFCL_03948 1.3e-86 spsL 5.1.3.13 M Spore Coat
OFKINFCL_03949 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OFKINFCL_03950 1.5e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OFKINFCL_03951 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OFKINFCL_03952 1.3e-185 spsG M Spore Coat
OFKINFCL_03953 5.3e-130 spsF M Spore Coat
OFKINFCL_03954 3.5e-213 spsE 2.5.1.56 M acid synthase
OFKINFCL_03955 7.5e-163 spsD 2.3.1.210 K Spore Coat
OFKINFCL_03956 5.1e-223 spsC E Belongs to the DegT DnrJ EryC1 family
OFKINFCL_03957 2.3e-267 spsB M Capsule polysaccharide biosynthesis protein
OFKINFCL_03958 7.7e-143 spsA M Spore Coat
OFKINFCL_03959 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
OFKINFCL_03960 4.3e-59 ywdK S small membrane protein
OFKINFCL_03961 3.7e-238 ywdJ F Xanthine uracil
OFKINFCL_03962 1.7e-48 ywdI S Family of unknown function (DUF5327)
OFKINFCL_03963 4.2e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OFKINFCL_03964 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OFKINFCL_03965 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
OFKINFCL_03967 5.2e-90 ywdD
OFKINFCL_03968 1.3e-57 pex K Transcriptional regulator PadR-like family
OFKINFCL_03969 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OFKINFCL_03970 2e-28 ywdA
OFKINFCL_03971 1.3e-284 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
OFKINFCL_03972 7.3e-253 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFKINFCL_03973 5.7e-138 focA P Formate/nitrite transporter
OFKINFCL_03974 2.7e-149 sacT K transcriptional antiterminator
OFKINFCL_03976 0.0 vpr O Belongs to the peptidase S8 family
OFKINFCL_03977 9.5e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFKINFCL_03978 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
OFKINFCL_03979 2.9e-202 rodA D Belongs to the SEDS family
OFKINFCL_03980 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
OFKINFCL_03981 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OFKINFCL_03982 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OFKINFCL_03983 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OFKINFCL_03984 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
OFKINFCL_03985 1e-35 ywzA S membrane
OFKINFCL_03986 4e-300 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OFKINFCL_03987 7.6e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OFKINFCL_03988 9.5e-60 gtcA S GtrA-like protein
OFKINFCL_03989 2.2e-122 ywcC K transcriptional regulator
OFKINFCL_03991 2.9e-48 ywcB S Protein of unknown function, DUF485
OFKINFCL_03992 6.9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OFKINFCL_03993 9.3e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OFKINFCL_03994 4.6e-222 ywbN P Dyp-type peroxidase family protein
OFKINFCL_03995 3.2e-185 ycdO P periplasmic lipoprotein involved in iron transport
OFKINFCL_03996 3.8e-252 P COG0672 High-affinity Fe2 Pb2 permease
OFKINFCL_03997 5.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
OFKINFCL_03998 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OFKINFCL_03999 4.3e-153 ywbI K Transcriptional regulator
OFKINFCL_04000 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
OFKINFCL_04001 2.3e-111 ywbG M effector of murein hydrolase
OFKINFCL_04002 3.7e-208 ywbF EGP Major facilitator Superfamily
OFKINFCL_04003 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
OFKINFCL_04004 4.1e-220 ywbD 2.1.1.191 J Methyltransferase
OFKINFCL_04005 4.4e-67 ywbC 4.4.1.5 E glyoxalase
OFKINFCL_04006 8.3e-125 ywbB S Protein of unknown function (DUF2711)
OFKINFCL_04007 6.4e-246 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OFKINFCL_04008 4.9e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
OFKINFCL_04009 2.2e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFKINFCL_04010 2.6e-152 sacY K transcriptional antiterminator
OFKINFCL_04011 4.5e-168 gspA M General stress
OFKINFCL_04012 6e-126 ywaF S Integral membrane protein
OFKINFCL_04013 4e-87 ywaE K Transcriptional regulator
OFKINFCL_04014 1.3e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OFKINFCL_04015 3e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
OFKINFCL_04016 1.4e-92 K Helix-turn-helix XRE-family like proteins
OFKINFCL_04017 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
OFKINFCL_04018 3e-130 ynfM EGP Major facilitator Superfamily
OFKINFCL_04019 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
OFKINFCL_04020 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
OFKINFCL_04021 5.1e-15 S D-Ala-teichoic acid biosynthesis protein
OFKINFCL_04022 2.5e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFKINFCL_04023 1.2e-232 dltB M membrane protein involved in D-alanine export
OFKINFCL_04024 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFKINFCL_04025 2e-230 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OFKINFCL_04026 9.6e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
OFKINFCL_04027 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OFKINFCL_04028 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OFKINFCL_04029 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
OFKINFCL_04030 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OFKINFCL_04031 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
OFKINFCL_04032 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
OFKINFCL_04033 1.1e-19 yxzF
OFKINFCL_04034 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
OFKINFCL_04035 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OFKINFCL_04036 4.5e-214 yxlH EGP Major facilitator Superfamily
OFKINFCL_04037 4e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OFKINFCL_04038 2.2e-165 yxlF V ABC transporter, ATP-binding protein
OFKINFCL_04039 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
OFKINFCL_04040 1.2e-31
OFKINFCL_04041 3.9e-48 yxlC S Family of unknown function (DUF5345)
OFKINFCL_04042 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
OFKINFCL_04043 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
OFKINFCL_04044 5.3e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OFKINFCL_04045 0.0 cydD V ATP-binding protein
OFKINFCL_04046 3.5e-310 cydD V ATP-binding
OFKINFCL_04047 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
OFKINFCL_04048 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
OFKINFCL_04049 1.5e-229 cimH C COG3493 Na citrate symporter
OFKINFCL_04050 3.5e-310 3.4.24.84 O Peptidase family M48
OFKINFCL_04052 6.2e-154 yxkH G Polysaccharide deacetylase
OFKINFCL_04053 5.9e-205 msmK P Belongs to the ABC transporter superfamily
OFKINFCL_04054 4.1e-164 lrp QT PucR C-terminal helix-turn-helix domain
OFKINFCL_04055 1.3e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OFKINFCL_04056 7.3e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OFKINFCL_04057 2.8e-74 yxkC S Domain of unknown function (DUF4352)
OFKINFCL_04058 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OFKINFCL_04059 3.4e-77 S Protein of unknown function (DUF1453)
OFKINFCL_04060 8.3e-192 yxjM T Signal transduction histidine kinase
OFKINFCL_04061 7.8e-112 K helix_turn_helix, Lux Regulon
OFKINFCL_04062 4.7e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OFKINFCL_04065 5e-43 yxjI S LURP-one-related
OFKINFCL_04066 1.6e-17 yxjI S LURP-one-related
OFKINFCL_04067 5.7e-219 yxjG 2.1.1.14 E Methionine synthase
OFKINFCL_04068 4.8e-218 yxjG 2.1.1.14 E Methionine synthase
OFKINFCL_04069 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
OFKINFCL_04070 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OFKINFCL_04071 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OFKINFCL_04072 1.7e-252 yxjC EG COG2610 H gluconate symporter and related permeases
OFKINFCL_04073 2.7e-157 rlmA 2.1.1.187 Q Methyltransferase domain
OFKINFCL_04074 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OFKINFCL_04075 4e-103 T Domain of unknown function (DUF4163)
OFKINFCL_04076 5.1e-47 yxiS
OFKINFCL_04077 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
OFKINFCL_04078 2.5e-223 citH C Citrate transporter
OFKINFCL_04079 3.3e-143 exoK GH16 M licheninase activity
OFKINFCL_04080 1.6e-149 licT K transcriptional antiterminator
OFKINFCL_04081 6.2e-112
OFKINFCL_04082 1.6e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
OFKINFCL_04083 4.3e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
OFKINFCL_04084 2.2e-210 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
OFKINFCL_04087 1.6e-48 yxiJ S YxiJ-like protein
OFKINFCL_04088 6.5e-63 yxiI S Protein of unknown function (DUF2716)
OFKINFCL_04089 7.2e-142
OFKINFCL_04090 3.7e-75 yxiG
OFKINFCL_04091 6.4e-63
OFKINFCL_04092 1.1e-83
OFKINFCL_04093 1.5e-71 yxxG
OFKINFCL_04094 0.0 wapA M COG3209 Rhs family protein
OFKINFCL_04095 2.8e-163 yxxF EG EamA-like transporter family
OFKINFCL_04096 1.1e-72 yxiE T Belongs to the universal stress protein A family
OFKINFCL_04097 2.7e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFKINFCL_04098 1.5e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFKINFCL_04099 9.6e-26
OFKINFCL_04101 5.5e-57
OFKINFCL_04102 3.9e-27
OFKINFCL_04103 3.4e-42
OFKINFCL_04104 5.2e-56
OFKINFCL_04105 1.1e-212 S nuclease activity
OFKINFCL_04106 1.4e-38 yxiC S Family of unknown function (DUF5344)
OFKINFCL_04107 2.3e-20 S Domain of unknown function (DUF5082)
OFKINFCL_04108 7.9e-279 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OFKINFCL_04109 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
OFKINFCL_04110 1.3e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
OFKINFCL_04111 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OFKINFCL_04112 2.8e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
OFKINFCL_04113 4e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
OFKINFCL_04114 2.8e-249 lysP E amino acid
OFKINFCL_04115 1.8e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
OFKINFCL_04116 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OFKINFCL_04117 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OFKINFCL_04118 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OFKINFCL_04119 2.5e-148 yxxB S Domain of Unknown Function (DUF1206)
OFKINFCL_04120 2.7e-197 eutH E Ethanolamine utilisation protein, EutH
OFKINFCL_04121 6.2e-249 yxeQ S MmgE/PrpD family
OFKINFCL_04122 2.3e-212 yxeP 3.5.1.47 E hydrolase activity
OFKINFCL_04123 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
OFKINFCL_04124 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
OFKINFCL_04125 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
OFKINFCL_04126 1.6e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFKINFCL_04127 9.2e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFKINFCL_04128 6.1e-185 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
OFKINFCL_04129 4.4e-149 yidA S hydrolases of the HAD superfamily
OFKINFCL_04132 1.3e-20 yxeE
OFKINFCL_04133 5.6e-16 yxeD
OFKINFCL_04134 8.5e-69
OFKINFCL_04135 2.3e-176 fhuD P ABC transporter
OFKINFCL_04136 1.5e-58 yxeA S Protein of unknown function (DUF1093)
OFKINFCL_04137 0.0 yxdM V ABC transporter (permease)
OFKINFCL_04138 9.4e-141 yxdL V ABC transporter, ATP-binding protein
OFKINFCL_04139 2e-180 T PhoQ Sensor
OFKINFCL_04140 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFKINFCL_04141 3e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
OFKINFCL_04142 4.7e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
OFKINFCL_04143 8.6e-167 iolH G Xylose isomerase-like TIM barrel
OFKINFCL_04144 1.4e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
OFKINFCL_04145 9.6e-234 iolF EGP Major facilitator Superfamily
OFKINFCL_04146 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
OFKINFCL_04147 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
OFKINFCL_04148 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
OFKINFCL_04149 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
OFKINFCL_04150 1.1e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OFKINFCL_04151 9.5e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
OFKINFCL_04152 8.3e-176 iolS C Aldo keto reductase
OFKINFCL_04154 8.3e-48 yxcD S Protein of unknown function (DUF2653)
OFKINFCL_04155 1.1e-245 csbC EGP Major facilitator Superfamily
OFKINFCL_04156 0.0 htpG O Molecular chaperone. Has ATPase activity
OFKINFCL_04158 1.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
OFKINFCL_04159 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
OFKINFCL_04160 1.3e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OFKINFCL_04162 1.9e-21 yxaI S membrane protein domain
OFKINFCL_04163 5.3e-77 S PQQ-like domain
OFKINFCL_04164 3.5e-65 S Family of unknown function (DUF5391)
OFKINFCL_04165 1.4e-75 yxaI S membrane protein domain
OFKINFCL_04166 7.9e-227 P Protein of unknown function (DUF418)
OFKINFCL_04167 3.8e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
OFKINFCL_04168 2.3e-99 yxaF K Transcriptional regulator
OFKINFCL_04169 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OFKINFCL_04170 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
OFKINFCL_04171 8.7e-48 S LrgA family
OFKINFCL_04172 2.6e-118 yxaC M effector of murein hydrolase
OFKINFCL_04173 1.3e-190 yxaB GM Polysaccharide pyruvyl transferase
OFKINFCL_04174 3.6e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OFKINFCL_04175 7.3e-127 gntR K transcriptional
OFKINFCL_04176 9.5e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
OFKINFCL_04177 2.5e-229 gntP EG COG2610 H gluconate symporter and related permeases
OFKINFCL_04178 3.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OFKINFCL_04179 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
OFKINFCL_04180 1.9e-286 ahpF O Alkyl hydroperoxide reductase
OFKINFCL_04181 1.6e-188 wgaE S Polysaccharide pyruvyl transferase
OFKINFCL_04182 6e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFKINFCL_04183 3.7e-32 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
OFKINFCL_04184 1.1e-124 yydK K Transcriptional regulator
OFKINFCL_04185 7.6e-13
OFKINFCL_04186 8.9e-117 S ABC-2 family transporter protein
OFKINFCL_04187 9e-91 prrC P ABC transporter
OFKINFCL_04189 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
OFKINFCL_04191 1.5e-18 S DNA-sulfur modification-associated
OFKINFCL_04192 1.5e-11 sfsA S Belongs to the SfsA family
OFKINFCL_04193 1.1e-27 sfsA S Belongs to the SfsA family
OFKINFCL_04194 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OFKINFCL_04195 1.6e-141
OFKINFCL_04196 3.8e-149 KLT serine threonine protein kinase
OFKINFCL_04197 5.7e-201 S Domain of unknown function (DUF4338)
OFKINFCL_04199 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OFKINFCL_04200 1.1e-09 S YyzF-like protein
OFKINFCL_04201 6.7e-61
OFKINFCL_04202 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OFKINFCL_04204 1.7e-30 yycQ S Protein of unknown function (DUF2651)
OFKINFCL_04205 5.3e-204 yycP
OFKINFCL_04206 2.9e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OFKINFCL_04207 7.1e-83 yycN 2.3.1.128 K Acetyltransferase
OFKINFCL_04208 8.8e-185 S aspartate phosphatase
OFKINFCL_04210 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
OFKINFCL_04211 9.7e-261 rocE E amino acid
OFKINFCL_04212 4.7e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
OFKINFCL_04213 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OFKINFCL_04214 1.4e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
OFKINFCL_04215 1.5e-94 K PFAM response regulator receiver
OFKINFCL_04216 1.2e-73 S Peptidase propeptide and YPEB domain
OFKINFCL_04217 3.8e-18 S Peptidase propeptide and YPEB domain
OFKINFCL_04218 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OFKINFCL_04219 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
OFKINFCL_04220 1.1e-153 yycI S protein conserved in bacteria
OFKINFCL_04221 2.9e-257 yycH S protein conserved in bacteria
OFKINFCL_04222 0.0 vicK 2.7.13.3 T Histidine kinase
OFKINFCL_04223 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFKINFCL_04228 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OFKINFCL_04229 1.5e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OFKINFCL_04230 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OFKINFCL_04231 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
OFKINFCL_04233 1.9e-15 yycC K YycC-like protein
OFKINFCL_04234 1.2e-219 yeaN P COG2807 Cyanate permease
OFKINFCL_04235 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OFKINFCL_04236 2.2e-73 rplI J binds to the 23S rRNA
OFKINFCL_04237 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OFKINFCL_04238 2.9e-160 yybS S membrane
OFKINFCL_04240 3.3e-83 cotF M Spore coat protein
OFKINFCL_04241 1.7e-66 ydeP3 K Transcriptional regulator
OFKINFCL_04242 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
OFKINFCL_04243 1.2e-58
OFKINFCL_04245 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
OFKINFCL_04246 2.4e-109 K TipAS antibiotic-recognition domain
OFKINFCL_04247 2e-122
OFKINFCL_04248 6.5e-66 yybH S SnoaL-like domain
OFKINFCL_04249 1.8e-121 yybG S Pentapeptide repeat-containing protein
OFKINFCL_04250 4.3e-217 ynfM EGP Major facilitator Superfamily
OFKINFCL_04251 6.9e-164 yybE K Transcriptional regulator
OFKINFCL_04252 2.9e-78 yjcF S Acetyltransferase (GNAT) domain
OFKINFCL_04253 8.9e-73 yybC
OFKINFCL_04254 5.3e-124 S Metallo-beta-lactamase superfamily
OFKINFCL_04255 5.6e-77 yybA 2.3.1.57 K transcriptional
OFKINFCL_04256 2.4e-72 yjcF S Acetyltransferase (GNAT) domain
OFKINFCL_04257 5.5e-96 yyaS S Membrane
OFKINFCL_04258 3e-90 yyaR K Acetyltransferase (GNAT) domain
OFKINFCL_04259 3e-65 yyaQ S YjbR
OFKINFCL_04260 2.6e-103 yyaP 1.5.1.3 H RibD C-terminal domain
OFKINFCL_04261 1.7e-249 tetL EGP Major facilitator Superfamily
OFKINFCL_04262 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
OFKINFCL_04263 5.1e-61 yyaN K MerR HTH family regulatory protein
OFKINFCL_04264 2.2e-160 yyaM EG EamA-like transporter family
OFKINFCL_04265 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
OFKINFCL_04266 8e-168 yyaK S CAAX protease self-immunity
OFKINFCL_04267 3.9e-243 EGP Major facilitator superfamily
OFKINFCL_04268 9.6e-95 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
OFKINFCL_04269 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OFKINFCL_04270 6.8e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
OFKINFCL_04271 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
OFKINFCL_04272 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OFKINFCL_04273 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OFKINFCL_04274 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
OFKINFCL_04275 3.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OFKINFCL_04276 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OFKINFCL_04277 2.3e-33 yyzM S protein conserved in bacteria
OFKINFCL_04278 8.1e-177 yyaD S Membrane
OFKINFCL_04279 2.8e-111 yyaC S Sporulation protein YyaC
OFKINFCL_04280 2.1e-149 spo0J K Belongs to the ParB family
OFKINFCL_04281 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
OFKINFCL_04282 1.3e-73 S Bacterial PH domain
OFKINFCL_04283 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
OFKINFCL_04284 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
OFKINFCL_04285 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OFKINFCL_04286 8.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OFKINFCL_04287 6.5e-108 jag S single-stranded nucleic acid binding R3H
OFKINFCL_04288 1.9e-117 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OFKINFCL_04289 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)