ORF_ID e_value Gene_name EC_number CAZy COGs Description
CADDLEGK_00001 2.7e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CADDLEGK_00002 7.1e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CADDLEGK_00003 5.2e-298 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CADDLEGK_00004 1.5e-86 ytsP 1.8.4.14 T GAF domain-containing protein
CADDLEGK_00005 1.6e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CADDLEGK_00006 6.5e-21 WQ51_02665 S Protein of unknown function (DUF3042)
CADDLEGK_00007 6.6e-08
CADDLEGK_00008 5.6e-132 K cell adhesion
CADDLEGK_00010 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CADDLEGK_00011 9.1e-215 XK27_05110 P Chloride transporter ClC family
CADDLEGK_00012 1.9e-40 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
CADDLEGK_00013 1.9e-278 clcA P Chloride transporter, ClC family
CADDLEGK_00014 1e-75 fld C Flavodoxin
CADDLEGK_00015 9.8e-19 XK27_08880
CADDLEGK_00016 1.6e-126 XK27_08875 O Zinc-dependent metalloprotease
CADDLEGK_00017 3.1e-147 estA CE1 S Esterase
CADDLEGK_00018 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CADDLEGK_00019 3.1e-136 XK27_08845 S abc transporter atp-binding protein
CADDLEGK_00020 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
CADDLEGK_00021 2.8e-177 XK27_08835 S ABC transporter substrate binding protein
CADDLEGK_00022 3.8e-18 S Domain of unknown function (DUF4649)
CADDLEGK_00023 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CADDLEGK_00024 2.1e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CADDLEGK_00025 0.0 dnaE 2.7.7.7 L DNA polymerase
CADDLEGK_00026 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CADDLEGK_00027 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CADDLEGK_00028 1.9e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CADDLEGK_00029 4.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CADDLEGK_00030 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CADDLEGK_00031 1.8e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
CADDLEGK_00033 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CADDLEGK_00034 2.9e-94 ypmS S Protein conserved in bacteria
CADDLEGK_00035 6.9e-156 ypmR E COG2755 Lysophospholipase L1 and related esterases
CADDLEGK_00036 1.3e-143 DegV S DegV family
CADDLEGK_00037 3.9e-301 recN L May be involved in recombinational repair of damaged DNA
CADDLEGK_00038 8.3e-73 argR K Regulates arginine biosynthesis genes
CADDLEGK_00039 4.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CADDLEGK_00040 1.3e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CADDLEGK_00041 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CADDLEGK_00042 3.6e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CADDLEGK_00044 1.3e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CADDLEGK_00045 1.3e-125 dnaD
CADDLEGK_00046 1.5e-180 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CADDLEGK_00047 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CADDLEGK_00048 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
CADDLEGK_00049 6.1e-67 GnaT 2.5.1.16 K acetyltransferase
CADDLEGK_00050 1.5e-33 Q Methyltransferase domain
CADDLEGK_00051 6.3e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CADDLEGK_00052 4.6e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CADDLEGK_00053 5.8e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
CADDLEGK_00054 3.2e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CADDLEGK_00055 1.5e-237 rodA D Belongs to the SEDS family
CADDLEGK_00056 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
CADDLEGK_00057 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
CADDLEGK_00058 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
CADDLEGK_00059 6.1e-180 XK27_08075 M glycosyl transferase family 2
CADDLEGK_00060 6.2e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
CADDLEGK_00061 1.4e-147 P molecular chaperone
CADDLEGK_00062 3.7e-96 XK27_05505 S Psort location CytoplasmicMembrane, score
CADDLEGK_00064 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
CADDLEGK_00065 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CADDLEGK_00066 7.3e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CADDLEGK_00067 2.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CADDLEGK_00068 2.3e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CADDLEGK_00069 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
CADDLEGK_00070 1.6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CADDLEGK_00071 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CADDLEGK_00072 5.5e-178 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CADDLEGK_00073 4.2e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CADDLEGK_00074 1.8e-60 XK27_08085
CADDLEGK_00075 8e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
CADDLEGK_00079 5.4e-44 spiA K sequence-specific DNA binding
CADDLEGK_00081 1.3e-134 agrA KT LytTr DNA-binding domain
CADDLEGK_00082 2.7e-228 blpH 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
CADDLEGK_00087 1.1e-25 S Bacteriocin class II with double-glycine leader peptide
CADDLEGK_00088 0.0 mdlB V abc transporter atp-binding protein
CADDLEGK_00089 0.0 mdlA V abc transporter atp-binding protein
CADDLEGK_00092 3e-90 XK27_09885 V Glycopeptide antibiotics resistance protein
CADDLEGK_00093 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CADDLEGK_00094 4.7e-65 yutD J protein conserved in bacteria
CADDLEGK_00095 1.3e-257 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CADDLEGK_00098 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CADDLEGK_00099 1.7e-182 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CADDLEGK_00100 0.0 ftsI 3.4.16.4 M penicillin-binding protein
CADDLEGK_00101 2.4e-45 ftsL D cell division protein FtsL
CADDLEGK_00102 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CADDLEGK_00105 1.9e-68 yhaI J Protein of unknown function (DUF805)
CADDLEGK_00106 4.3e-65 yhaI S Protein of unknown function (DUF805)
CADDLEGK_00107 1.5e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CADDLEGK_00108 5.2e-142 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CADDLEGK_00109 2.1e-272 XK27_00765
CADDLEGK_00110 4.4e-132 ecsA_2 V abc transporter atp-binding protein
CADDLEGK_00111 3.1e-125 S Protein of unknown function (DUF554)
CADDLEGK_00112 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CADDLEGK_00113 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CADDLEGK_00114 3e-246 2.7.13.3 T protein histidine kinase activity
CADDLEGK_00115 4.1e-237 dcuS 2.7.13.3 T protein histidine kinase activity
CADDLEGK_00116 8.9e-14
CADDLEGK_00119 5.8e-146 V Psort location CytoplasmicMembrane, score
CADDLEGK_00121 9.2e-300 O MreB/Mbl protein
CADDLEGK_00122 6.3e-112 liaI S membrane
CADDLEGK_00123 6.8e-75 XK27_02470 K LytTr DNA-binding domain protein
CADDLEGK_00124 7.8e-297 KT response to antibiotic
CADDLEGK_00125 1.5e-110 yebC M Membrane
CADDLEGK_00126 1.8e-259 XK27_03190 S hydrolases of the HAD superfamily
CADDLEGK_00127 1.6e-177 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CADDLEGK_00129 2.9e-31 yozG K Transcriptional regulator
CADDLEGK_00133 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CADDLEGK_00134 2.2e-191 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CADDLEGK_00135 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CADDLEGK_00136 1.9e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CADDLEGK_00137 3.3e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CADDLEGK_00138 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CADDLEGK_00140 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
CADDLEGK_00141 4.5e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
CADDLEGK_00142 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CADDLEGK_00143 4.4e-285 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
CADDLEGK_00144 6e-177 scrR K purine nucleotide biosynthetic process
CADDLEGK_00145 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CADDLEGK_00146 1.7e-61 yqhY S protein conserved in bacteria
CADDLEGK_00147 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CADDLEGK_00148 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
CADDLEGK_00149 6.3e-188 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
CADDLEGK_00150 7.2e-65 L Transposase (IS116 IS110 IS902 family)
CADDLEGK_00151 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CADDLEGK_00153 5.1e-73 K Helix-turn-helix
CADDLEGK_00155 1.5e-166 fhuR K transcriptional regulator (lysR family)
CADDLEGK_00156 9.8e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CADDLEGK_00157 4.2e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CADDLEGK_00158 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CADDLEGK_00159 1.6e-222 pyrP F uracil Permease
CADDLEGK_00160 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CADDLEGK_00161 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
CADDLEGK_00162 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
CADDLEGK_00163 4.6e-132 2.1.1.223 S Putative SAM-dependent methyltransferase
CADDLEGK_00164 3.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CADDLEGK_00165 9.9e-121 macB V ABC transporter, ATP-binding protein
CADDLEGK_00166 3e-210 V permease protein
CADDLEGK_00167 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CADDLEGK_00168 7.9e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CADDLEGK_00169 0.0 mdlB V abc transporter atp-binding protein
CADDLEGK_00170 0.0 lmrA V abc transporter atp-binding protein
CADDLEGK_00171 8.7e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CADDLEGK_00172 4e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CADDLEGK_00173 1.8e-197 yceA S Belongs to the UPF0176 family
CADDLEGK_00174 1.6e-28 XK27_00085 K Transcriptional
CADDLEGK_00175 2.1e-21
CADDLEGK_00176 1.1e-141 deoD_1 2.4.2.3 F Phosphorylase superfamily
CADDLEGK_00177 3.9e-114 S VIT family
CADDLEGK_00178 3.5e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CADDLEGK_00179 2.8e-218 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CADDLEGK_00180 4.4e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
CADDLEGK_00182 2.8e-140 E Alpha beta hydrolase
CADDLEGK_00183 1.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CADDLEGK_00184 3.9e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
CADDLEGK_00185 1.7e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CADDLEGK_00186 7.8e-172 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
CADDLEGK_00187 1.7e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CADDLEGK_00189 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
CADDLEGK_00190 8.3e-257 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CADDLEGK_00191 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
CADDLEGK_00192 2.9e-25
CADDLEGK_00193 1.7e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CADDLEGK_00194 0.0 U protein secretion
CADDLEGK_00195 2.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
CADDLEGK_00196 3.7e-246 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
CADDLEGK_00197 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CADDLEGK_00198 1.7e-160 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CADDLEGK_00199 1.2e-194 S Protein of unknown function (DUF3114)
CADDLEGK_00200 4.1e-29 pspC KT PspC domain protein
CADDLEGK_00201 5.2e-119 yqfA K protein, Hemolysin III
CADDLEGK_00202 8.6e-78 K hmm pf08876
CADDLEGK_00203 2.8e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
CADDLEGK_00204 6.9e-212 mvaS 2.3.3.10 I synthase
CADDLEGK_00205 2.3e-63 L Transposase (IS116 IS110 IS902 family)
CADDLEGK_00206 0.0 M family 8
CADDLEGK_00207 3e-108 cutC P Participates in the control of copper homeostasis
CADDLEGK_00208 8.9e-129 S CAAX amino terminal protease family
CADDLEGK_00209 1.6e-97 ypgQ F HD superfamily hydrolase
CADDLEGK_00210 5.2e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
CADDLEGK_00211 2.2e-151 yitS S EDD domain protein, DegV family
CADDLEGK_00212 9.1e-204 yeaN P transporter
CADDLEGK_00213 4e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CADDLEGK_00214 4.1e-56 S ParE toxin of type II toxin-antitoxin system, parDE
CADDLEGK_00215 2.4e-44
CADDLEGK_00216 9.1e-51 ycf23 1.1.1.205, 1.13.12.16 S 2-Nitropropane dioxygenase
CADDLEGK_00217 3.6e-85
CADDLEGK_00218 2.7e-181
CADDLEGK_00219 1.5e-127 S CAAX amino terminal protease family protein
CADDLEGK_00220 8.6e-105 L Transposase
CADDLEGK_00221 8.9e-105 L Transposase
CADDLEGK_00222 1.2e-92
CADDLEGK_00223 1.8e-181
CADDLEGK_00224 3.3e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CADDLEGK_00225 2.9e-96 mip S hydroperoxide reductase activity
CADDLEGK_00226 1.1e-200 I acyl-CoA dehydrogenase
CADDLEGK_00227 1.3e-152 ydiA P C4-dicarboxylate transporter malic acid transport
CADDLEGK_00228 1.8e-238 msrR K Transcriptional regulator
CADDLEGK_00229 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
CADDLEGK_00230 8.8e-76 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CADDLEGK_00231 1.6e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CADDLEGK_00232 7.2e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CADDLEGK_00233 4.2e-53 yheA S Belongs to the UPF0342 family
CADDLEGK_00234 8.3e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CADDLEGK_00235 9.9e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CADDLEGK_00236 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CADDLEGK_00237 3.5e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CADDLEGK_00238 2.1e-120 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CADDLEGK_00239 3.8e-218 ywbD 2.1.1.191 J Methyltransferase
CADDLEGK_00240 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CADDLEGK_00241 1.2e-25 WQ51_00785
CADDLEGK_00242 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CADDLEGK_00243 8.7e-78 yueI S Protein of unknown function (DUF1694)
CADDLEGK_00244 1.8e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CADDLEGK_00245 4.2e-200 yyaQ S YjbR
CADDLEGK_00246 2.4e-181 ccpA K Catabolite control protein A
CADDLEGK_00247 1.7e-196 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
CADDLEGK_00248 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
CADDLEGK_00249 5.7e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CADDLEGK_00250 1.9e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CADDLEGK_00251 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CADDLEGK_00252 2e-33 secG U Preprotein translocase subunit SecG
CADDLEGK_00253 1e-221 mdtG EGP Major facilitator Superfamily
CADDLEGK_00254 2.4e-96 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CADDLEGK_00255 3.7e-151 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CADDLEGK_00256 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CADDLEGK_00257 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CADDLEGK_00258 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CADDLEGK_00259 4e-153 licT K antiterminator
CADDLEGK_00260 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CADDLEGK_00261 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
CADDLEGK_00262 5.2e-145 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CADDLEGK_00263 1.4e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CADDLEGK_00264 1.3e-150 I Alpha/beta hydrolase family
CADDLEGK_00265 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CADDLEGK_00266 1.3e-134 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CADDLEGK_00267 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CADDLEGK_00268 4.3e-215 ftsW D Belongs to the SEDS family
CADDLEGK_00269 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CADDLEGK_00270 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CADDLEGK_00271 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CADDLEGK_00272 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CADDLEGK_00273 1.7e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CADDLEGK_00274 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CADDLEGK_00275 2.8e-123 atpB C it plays a direct role in the translocation of protons across the membrane
CADDLEGK_00276 5.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CADDLEGK_00277 1.6e-187 femA 2.3.2.10, 2.3.2.16 V FemAB family
CADDLEGK_00279 1e-57 arsC 1.20.4.1 P Belongs to the ArsC family
CADDLEGK_00280 3.5e-72 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
CADDLEGK_00281 7.4e-222 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CADDLEGK_00282 1e-104 wecD M Acetyltransferase (GNAT) domain
CADDLEGK_00283 3.9e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CADDLEGK_00284 5.5e-161 GK ROK family
CADDLEGK_00285 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
CADDLEGK_00286 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
CADDLEGK_00287 4.4e-205 potD P spermidine putrescine ABC transporter
CADDLEGK_00288 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
CADDLEGK_00289 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
CADDLEGK_00290 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CADDLEGK_00291 7.3e-169 murB 1.3.1.98 M cell wall formation
CADDLEGK_00292 2e-80 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CADDLEGK_00293 4.5e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CADDLEGK_00294 1.4e-291 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
CADDLEGK_00295 1.6e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CADDLEGK_00296 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
CADDLEGK_00297 0.0 ydaO E amino acid
CADDLEGK_00298 4.1e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CADDLEGK_00299 2.4e-37 ylqC L Belongs to the UPF0109 family
CADDLEGK_00300 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CADDLEGK_00302 7.8e-198 2.7.13.3 T GHKL domain
CADDLEGK_00303 2.1e-129 agrA KT phosphorelay signal transduction system
CADDLEGK_00304 2.8e-190 O protein import
CADDLEGK_00305 5.1e-167 tehB 2.1.1.265 PQ tellurite resistance protein tehb
CADDLEGK_00306 2.9e-17 yjdB S Domain of unknown function (DUF4767)
CADDLEGK_00307 2.7e-199 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CADDLEGK_00309 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
CADDLEGK_00310 4.4e-72 S QueT transporter
CADDLEGK_00312 2.2e-171 yfjR K regulation of single-species biofilm formation
CADDLEGK_00313 7.4e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CADDLEGK_00314 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CADDLEGK_00315 8.2e-85 ccl S cog cog4708
CADDLEGK_00316 3.7e-163 rbn E Belongs to the UPF0761 family
CADDLEGK_00317 1.2e-165 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
CADDLEGK_00318 1.1e-231 ytoI K transcriptional regulator containing CBS domains
CADDLEGK_00319 2e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
CADDLEGK_00320 7.1e-138 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
CADDLEGK_00321 6.5e-119 ylfI S tigr01906
CADDLEGK_00322 1.4e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CADDLEGK_00323 1.3e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
CADDLEGK_00324 2.9e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
CADDLEGK_00325 2.9e-30 KT response to antibiotic
CADDLEGK_00327 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CADDLEGK_00328 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CADDLEGK_00329 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CADDLEGK_00330 2.5e-258 S phospholipase Carboxylesterase
CADDLEGK_00331 1.1e-200 yurR 1.4.5.1 E oxidoreductase
CADDLEGK_00332 8e-146 zupT P Mediates zinc uptake. May also transport other divalent cations
CADDLEGK_00333 2.2e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CADDLEGK_00334 2.6e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
CADDLEGK_00335 1.3e-64 gtrA S GtrA-like protein
CADDLEGK_00336 8.2e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CADDLEGK_00337 6e-169 ybbR S Protein conserved in bacteria
CADDLEGK_00338 1.5e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CADDLEGK_00339 3.1e-256 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
CADDLEGK_00340 8.7e-150 cobQ S glutamine amidotransferase
CADDLEGK_00341 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CADDLEGK_00342 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
CADDLEGK_00343 1.6e-39 MA20_06245 S yiaA/B two helix domain
CADDLEGK_00344 0.0 uup S abc transporter atp-binding protein
CADDLEGK_00345 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
CADDLEGK_00346 3.2e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
CADDLEGK_00347 3.8e-226 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
CADDLEGK_00348 2.7e-153 XK27_05675 S Esterase
CADDLEGK_00349 6.1e-162 XK27_05670 S Putative esterase
CADDLEGK_00350 1.9e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
CADDLEGK_00351 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CADDLEGK_00352 3e-38 ptsH G phosphocarrier protein Hpr
CADDLEGK_00353 3.9e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
CADDLEGK_00354 2.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
CADDLEGK_00355 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CADDLEGK_00356 2.9e-34 nrdH O Glutaredoxin
CADDLEGK_00357 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CADDLEGK_00358 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CADDLEGK_00359 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CADDLEGK_00360 8.4e-138 divIVA D Cell division initiation protein
CADDLEGK_00361 1.9e-144 ylmH S conserved protein, contains S4-like domain
CADDLEGK_00362 6.5e-30 yggT D integral membrane protein
CADDLEGK_00363 3.2e-101 sepF D cell septum assembly
CADDLEGK_00364 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CADDLEGK_00365 3.2e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CADDLEGK_00366 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CADDLEGK_00371 2.6e-10
CADDLEGK_00374 1.9e-07
CADDLEGK_00379 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CADDLEGK_00380 1.5e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
CADDLEGK_00381 5.5e-36 XK27_02060 S Transglycosylase associated protein
CADDLEGK_00382 2.6e-71 badR K Transcriptional regulator, marr family
CADDLEGK_00383 3.2e-95 S reductase
CADDLEGK_00385 6.6e-287 ahpF O alkyl hydroperoxide reductase
CADDLEGK_00386 3.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
CADDLEGK_00387 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
CADDLEGK_00388 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CADDLEGK_00389 1.6e-82 S Putative small multi-drug export protein
CADDLEGK_00390 1.8e-75 ctsR K Belongs to the CtsR family
CADDLEGK_00391 0.0 clpC O Belongs to the ClpA ClpB family
CADDLEGK_00392 4.5e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CADDLEGK_00393 1.1e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CADDLEGK_00394 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CADDLEGK_00395 1e-139 S SseB protein N-terminal domain
CADDLEGK_00396 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
CADDLEGK_00398 8.1e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CADDLEGK_00399 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CADDLEGK_00401 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CADDLEGK_00402 2.7e-91 yacP S RNA-binding protein containing a PIN domain
CADDLEGK_00403 4.1e-153 degV S DegV family
CADDLEGK_00405 5.1e-22 K Transcriptional
CADDLEGK_00406 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CADDLEGK_00407 7.3e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
CADDLEGK_00408 1.7e-89 S Protein conserved in bacteria
CADDLEGK_00409 6.7e-89 H Methyltransferase
CADDLEGK_00410 3.4e-101 cadD P cadmium resistance
CADDLEGK_00411 4.5e-55 cadC K Bacterial regulatory protein, arsR family
CADDLEGK_00412 1.6e-16
CADDLEGK_00413 3.5e-49 yiiE S protein homotetramerization
CADDLEGK_00414 2.6e-18
CADDLEGK_00415 1.5e-29 K Helix-turn-helix domain
CADDLEGK_00416 6e-85
CADDLEGK_00417 8.5e-140 srtB 3.4.22.70 S sortase, SrtB family
CADDLEGK_00418 2.2e-232 capA M Bacterial capsule synthesis protein
CADDLEGK_00419 6.1e-39 gcvR T UPF0237 protein
CADDLEGK_00420 8.7e-243 XK27_08635 S UPF0210 protein
CADDLEGK_00421 5.6e-132 ais G Phosphoglycerate mutase
CADDLEGK_00422 6.7e-142 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
CADDLEGK_00423 1.2e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
CADDLEGK_00424 1.3e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CADDLEGK_00425 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CADDLEGK_00426 6e-303 dnaK O Heat shock 70 kDa protein
CADDLEGK_00427 1.7e-103 thiJ-2 3.5.1.124 S DJ-1/PfpI family
CADDLEGK_00428 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CADDLEGK_00429 2e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CADDLEGK_00430 2.4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
CADDLEGK_00431 7.4e-80 hmpT S cog cog4720
CADDLEGK_00432 3.5e-158 K sequence-specific DNA binding
CADDLEGK_00433 1.2e-09
CADDLEGK_00435 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
CADDLEGK_00436 1.6e-137 agrA KT response regulator
CADDLEGK_00437 3.1e-07
CADDLEGK_00438 5.6e-135 agrA KT response regulator
CADDLEGK_00439 6.8e-232 2.7.13.3 T GHKL domain
CADDLEGK_00441 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
CADDLEGK_00442 1.3e-142 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CADDLEGK_00443 9.1e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
CADDLEGK_00444 5.9e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CADDLEGK_00445 1.3e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CADDLEGK_00446 5.6e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
CADDLEGK_00447 7.2e-206 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
CADDLEGK_00448 3.6e-128 yxkH G deacetylase
CADDLEGK_00449 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CADDLEGK_00450 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CADDLEGK_00451 3.7e-149 rarD S Transporter
CADDLEGK_00452 2.6e-16 T peptidase
CADDLEGK_00453 3e-14 coiA 3.6.4.12 S Competence protein
CADDLEGK_00454 1.2e-103 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CADDLEGK_00455 6.6e-107 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CADDLEGK_00456 4.2e-175 S Helix-hairpin-helix DNA-binding motif class 1
CADDLEGK_00457 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CADDLEGK_00458 7.2e-164
CADDLEGK_00459 1.4e-218 dcm 2.1.1.37 H cytosine-specific methyltransferase
CADDLEGK_00460 1.2e-304
CADDLEGK_00461 3.5e-56 lrgA S Effector of murein hydrolase LrgA
CADDLEGK_00462 3.2e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CADDLEGK_00463 7.6e-100 3.1.3.18 S IA, variant 1
CADDLEGK_00464 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CADDLEGK_00465 6e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CADDLEGK_00466 3.5e-112 serB 3.1.3.3 E phosphoserine phosphatase
CADDLEGK_00467 2.5e-07 N PFAM Uncharacterised protein family UPF0150
CADDLEGK_00468 1.8e-151 EG Permeases of the drug metabolite transporter (DMT) superfamily
CADDLEGK_00470 2.3e-60 ycaO O OsmC-like protein
CADDLEGK_00471 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
CADDLEGK_00472 5.7e-10 O ADP-ribosylglycohydrolase
CADDLEGK_00473 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CADDLEGK_00475 1.5e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CADDLEGK_00476 1.7e-17 XK27_00735
CADDLEGK_00477 4.7e-25 L Transposase
CADDLEGK_00484 2.6e-10
CADDLEGK_00490 9.2e-110 mreC M Involved in formation and maintenance of cell shape
CADDLEGK_00491 4.2e-84 mreD M rod shape-determining protein MreD
CADDLEGK_00492 1.1e-89 usp 3.5.1.28 CBM50 S CHAP domain
CADDLEGK_00493 3.5e-48 L COG1943 Transposase and inactivated derivatives
CADDLEGK_00494 2.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CADDLEGK_00495 1.1e-217 araT 2.6.1.1 E Aminotransferase
CADDLEGK_00496 5.5e-141 recO L Involved in DNA repair and RecF pathway recombination
CADDLEGK_00497 6.2e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CADDLEGK_00498 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CADDLEGK_00499 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CADDLEGK_00500 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CADDLEGK_00501 6.4e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CADDLEGK_00502 1.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CADDLEGK_00503 8.8e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CADDLEGK_00504 4.7e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CADDLEGK_00505 3e-237 purD 6.3.4.13 F Belongs to the GARS family
CADDLEGK_00506 5.3e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CADDLEGK_00507 3.8e-196 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CADDLEGK_00508 3.1e-152
CADDLEGK_00509 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CADDLEGK_00510 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
CADDLEGK_00511 3.1e-69 argR K Regulates arginine biosynthesis genes
CADDLEGK_00512 1.9e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
CADDLEGK_00513 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CADDLEGK_00514 1e-78 S Protein of unknown function (DUF3021)
CADDLEGK_00515 1.4e-69 K LytTr DNA-binding domain
CADDLEGK_00517 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CADDLEGK_00519 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CADDLEGK_00520 2.3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
CADDLEGK_00521 4e-229 cinA 3.5.1.42 S Belongs to the CinA family
CADDLEGK_00522 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CADDLEGK_00523 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
CADDLEGK_00525 3.3e-117 nudL L hydrolase
CADDLEGK_00526 9.1e-53 K transcriptional regulator, PadR family
CADDLEGK_00527 1.9e-61 XK27_06920 S Protein of unknown function (DUF1700)
CADDLEGK_00528 3.7e-106 S Putative adhesin
CADDLEGK_00529 1.2e-157 XK27_06930 V domain protein
CADDLEGK_00530 3.8e-96 XK27_06935 K transcriptional regulator
CADDLEGK_00531 2e-53 ypaA M Membrane
CADDLEGK_00532 1.9e-10
CADDLEGK_00533 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CADDLEGK_00534 1.8e-47 veg S Biofilm formation stimulator VEG
CADDLEGK_00535 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CADDLEGK_00536 2.2e-73 rplI J binds to the 23S rRNA
CADDLEGK_00537 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CADDLEGK_00538 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CADDLEGK_00539 4.2e-99 yvbG U UPF0056 membrane protein
CADDLEGK_00540 5.6e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CADDLEGK_00541 0.0 S Bacterial membrane protein, YfhO
CADDLEGK_00542 5.8e-65 isaA GH23 M Immunodominant staphylococcal antigen A
CADDLEGK_00543 2.1e-57 lytE M LysM domain protein
CADDLEGK_00544 2.8e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CADDLEGK_00545 1.6e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CADDLEGK_00546 4.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CADDLEGK_00547 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CADDLEGK_00548 5.2e-132 S sequence-specific DNA binding
CADDLEGK_00549 5e-240 ymfH S Peptidase M16
CADDLEGK_00550 4.8e-235 ymfF S Peptidase M16
CADDLEGK_00551 8.9e-60 yaaA S S4 domain protein YaaA
CADDLEGK_00552 1e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CADDLEGK_00553 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CADDLEGK_00554 2.4e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
CADDLEGK_00555 7.1e-153 yvjA S membrane
CADDLEGK_00556 3.3e-305 ybiT S abc transporter atp-binding protein
CADDLEGK_00557 0.0 XK27_10405 S Bacterial membrane protein YfhO
CADDLEGK_00558 1.7e-102 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CADDLEGK_00559 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CADDLEGK_00560 1e-125 gntR1 K transcriptional
CADDLEGK_00561 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CADDLEGK_00562 2.9e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CADDLEGK_00563 2.7e-86
CADDLEGK_00564 2.7e-91 niaR S small molecule binding protein (contains 3H domain)
CADDLEGK_00565 4e-127 K DNA-binding helix-turn-helix protein
CADDLEGK_00566 2.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CADDLEGK_00567 7.7e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CADDLEGK_00568 4.4e-161 GK ROK family
CADDLEGK_00569 2.5e-155 dprA LU DNA protecting protein DprA
CADDLEGK_00570 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CADDLEGK_00571 4.6e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
CADDLEGK_00572 1.3e-51 V ABC-2 family transporter protein
CADDLEGK_00574 7.9e-146 S TraX protein
CADDLEGK_00575 4.3e-118 KT Transcriptional regulatory protein, C terminal
CADDLEGK_00576 4.7e-236 T PhoQ Sensor
CADDLEGK_00577 1.1e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CADDLEGK_00578 2.7e-224 XK27_05470 E Methionine synthase
CADDLEGK_00579 1.8e-50 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CADDLEGK_00580 2.5e-253 V Glucan-binding protein C
CADDLEGK_00581 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CADDLEGK_00582 1.3e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
CADDLEGK_00583 5.5e-95 S Protein of unknown function (DUF1697)
CADDLEGK_00584 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CADDLEGK_00585 2.3e-181 clcA_2 P Chloride transporter, ClC family
CADDLEGK_00586 5.8e-137 yfeJ 6.3.5.2 F glutamine amidotransferase
CADDLEGK_00587 5.3e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
CADDLEGK_00588 1e-20 L the current gene model (or a revised gene model) may contain a frame shift
CADDLEGK_00590 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CADDLEGK_00593 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CADDLEGK_00594 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
CADDLEGK_00595 4.3e-42 C Pyridoxamine 5'-phosphate oxidase
CADDLEGK_00596 5.8e-96 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
CADDLEGK_00597 4.5e-79 S Macro domain
CADDLEGK_00598 1.4e-67 mgrA K Transcriptional regulator, MarR family
CADDLEGK_00599 2e-147 1.6.5.2 GM NmrA family
CADDLEGK_00600 9.2e-122 proV E abc transporter atp-binding protein
CADDLEGK_00601 2.4e-233 proWX P ABC transporter
CADDLEGK_00602 5e-120 ybhF_2 V abc transporter atp-binding protein
CADDLEGK_00603 3.9e-161 ybhR V ABC transporter
CADDLEGK_00604 8.8e-97 K Bacterial regulatory proteins, tetR family
CADDLEGK_00605 4.8e-150 L Transposase
CADDLEGK_00606 1.8e-17 L Transposase
CADDLEGK_00607 1.2e-69 K Bacterial regulatory proteins, tetR family
CADDLEGK_00608 1.9e-266 P ABC transporter transmembrane region
CADDLEGK_00609 7.9e-265 ndvA 3.6.3.25 P ABC transporter transmembrane region
CADDLEGK_00610 1.8e-80 S Hypothetical bacterial integral membrane protein (Trep_Strep)
CADDLEGK_00611 2.4e-87 P cobalt transport protein
CADDLEGK_00612 3.8e-185 P AAA domain, putative AbiEii toxin, Type IV TA system
CADDLEGK_00613 0.0 V ABC transporter (Permease
CADDLEGK_00614 1.2e-123 V abc transporter atp-binding protein
CADDLEGK_00615 4.4e-92 tetR K transcriptional regulator
CADDLEGK_00616 1.7e-137 S Phenazine biosynthesis protein
CADDLEGK_00617 1.8e-91 2.7.7.65 T Psort location CytoplasmicMembrane, score
CADDLEGK_00618 3.1e-131 cbiQ P cobalt transport
CADDLEGK_00619 1e-156 P abc transporter atp-binding protein
CADDLEGK_00620 3.1e-147 cbiO2 P ABC transporter, ATP-binding protein
CADDLEGK_00621 2.5e-83 tnp L DDE domain
CADDLEGK_00622 1.4e-59 pnuC H nicotinamide mononucleotide transporter
CADDLEGK_00623 1.8e-11
CADDLEGK_00624 5.9e-61 S Protein of unknown function with HXXEE motif
CADDLEGK_00625 4.7e-105 K Transcriptional regulator, TetR family
CADDLEGK_00626 3.9e-154 czcD P cation diffusion facilitator family transporter
CADDLEGK_00627 2e-192 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CADDLEGK_00628 1.5e-186 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
CADDLEGK_00629 3.3e-42 2.4.2.3 F Phosphorylase superfamily
CADDLEGK_00630 8.3e-111 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
CADDLEGK_00631 1.5e-152 S von Willebrand factor (vWF) type A domain
CADDLEGK_00632 1.8e-181 yclQ P ABC-type enterochelin transport system, periplasmic component
CADDLEGK_00633 8.5e-227 dinF V Mate efflux family protein
CADDLEGK_00634 4.8e-261 S Psort location CytoplasmicMembrane, score
CADDLEGK_00635 5.1e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
CADDLEGK_00636 2.6e-133 S TraX protein
CADDLEGK_00637 2.7e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
CADDLEGK_00638 1.6e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CADDLEGK_00639 1e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CADDLEGK_00640 1.3e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CADDLEGK_00641 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CADDLEGK_00642 3.2e-243 nylA 3.5.1.4 J Belongs to the amidase family
CADDLEGK_00643 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
CADDLEGK_00644 2.1e-80 yecS P ABC transporter (Permease
CADDLEGK_00645 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
CADDLEGK_00646 6.6e-170 bglC K Transcriptional regulator
CADDLEGK_00647 3.6e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CADDLEGK_00648 2.4e-240 agcS E (Alanine) symporter
CADDLEGK_00649 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CADDLEGK_00650 4.3e-239 metY 2.5.1.49 E o-acetylhomoserine
CADDLEGK_00651 2.9e-27 S haloacid dehalogenase-like hydrolase
CADDLEGK_00652 8.7e-60 S haloacid dehalogenase-like hydrolase
CADDLEGK_00653 8.5e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CADDLEGK_00654 1.3e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
CADDLEGK_00655 6.1e-35 M1-755 P Hemerythrin HHE cation binding domain protein
CADDLEGK_00656 1.4e-237 XK27_04775 S hemerythrin HHE cation binding domain
CADDLEGK_00657 1.2e-149 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CADDLEGK_00658 6e-171 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CADDLEGK_00659 1.6e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CADDLEGK_00660 1e-44 yktA S Belongs to the UPF0223 family
CADDLEGK_00661 1.3e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
CADDLEGK_00662 1.6e-249 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
CADDLEGK_00663 9.9e-155 pstS P phosphate
CADDLEGK_00664 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
CADDLEGK_00665 1.5e-155 pstA P phosphate transport system permease
CADDLEGK_00666 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CADDLEGK_00667 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CADDLEGK_00668 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
CADDLEGK_00669 0.0 pepN 3.4.11.2 E aminopeptidase
CADDLEGK_00670 3.5e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
CADDLEGK_00671 2.7e-185 lplA 6.3.1.20 H Lipoate-protein ligase
CADDLEGK_00673 1.2e-11
CADDLEGK_00674 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CADDLEGK_00675 1e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
CADDLEGK_00676 8.7e-171 malR K Transcriptional regulator
CADDLEGK_00677 2.5e-228 malX G ABC transporter
CADDLEGK_00678 9.7e-250 malF P ABC transporter (Permease
CADDLEGK_00679 9.8e-152 malG P ABC transporter (Permease
CADDLEGK_00680 1.4e-212 msmX P Belongs to the ABC transporter superfamily
CADDLEGK_00681 9.5e-23 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CADDLEGK_00682 4.6e-118 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CADDLEGK_00683 3.8e-288 ywbL P COG0672 High-affinity Fe2 Pb2 permease
CADDLEGK_00684 3.9e-234 ycdB P peroxidase
CADDLEGK_00685 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
CADDLEGK_00686 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CADDLEGK_00687 1.5e-251 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CADDLEGK_00688 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
CADDLEGK_00689 0.0 lpdA 1.8.1.4 C Dehydrogenase
CADDLEGK_00690 2.2e-217 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CADDLEGK_00691 1.4e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CADDLEGK_00692 7.8e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
CADDLEGK_00693 9.4e-207 hpk9 2.7.13.3 T protein histidine kinase activity
CADDLEGK_00694 2.4e-234 2.7.13.3 T protein histidine kinase activity
CADDLEGK_00695 0.0 S the current gene model (or a revised gene model) may contain a frame shift
CADDLEGK_00696 7.5e-236 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CADDLEGK_00697 1.7e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CADDLEGK_00698 6e-219 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CADDLEGK_00699 2.4e-253 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
CADDLEGK_00700 1.5e-160 rssA S Phospholipase, patatin family
CADDLEGK_00701 6.7e-105 estA E Lysophospholipase L1 and related esterases
CADDLEGK_00702 3e-287 S unusual protein kinase
CADDLEGK_00703 4.9e-39 S granule-associated protein
CADDLEGK_00704 1.3e-284 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CADDLEGK_00705 1e-196 S hmm pf01594
CADDLEGK_00706 4e-107 G Belongs to the phosphoglycerate mutase family
CADDLEGK_00707 1e-105 G Belongs to the phosphoglycerate mutase family
CADDLEGK_00708 1.3e-108 pgm G Belongs to the phosphoglycerate mutase family
CADDLEGK_00709 2.4e-150 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CADDLEGK_00710 5.5e-243 S Polysaccharide biosynthesis protein
CADDLEGK_00711 0.0 M Polysaccharide biosynthesis protein
CADDLEGK_00712 1.3e-204 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CADDLEGK_00713 2.7e-171 S glycosyl transferase family 2
CADDLEGK_00714 4e-85
CADDLEGK_00715 4.4e-205 M glycosyl transferase group 1
CADDLEGK_00716 2e-163 S Glycosyl transferase family 2
CADDLEGK_00717 7.4e-160 licD M LICD family
CADDLEGK_00718 1.7e-126 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CADDLEGK_00719 2.8e-257 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
CADDLEGK_00720 6.1e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
CADDLEGK_00721 7.2e-116 cps4C M biosynthesis protein
CADDLEGK_00722 1.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
CADDLEGK_00723 4e-241 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
CADDLEGK_00724 9.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
CADDLEGK_00725 1.9e-272 pepV 3.5.1.18 E Dipeptidase
CADDLEGK_00726 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CADDLEGK_00727 1.9e-92 yybC
CADDLEGK_00728 1.1e-83 XK27_03610 K Gnat family
CADDLEGK_00729 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CADDLEGK_00730 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CADDLEGK_00731 5.6e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CADDLEGK_00732 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CADDLEGK_00733 2.4e-17 M LysM domain
CADDLEGK_00734 8.6e-87 ebsA S Family of unknown function (DUF5322)
CADDLEGK_00735 2e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CADDLEGK_00736 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
CADDLEGK_00737 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CADDLEGK_00738 4.4e-225 G COG0457 FOG TPR repeat
CADDLEGK_00739 4.3e-177 yubA S permease
CADDLEGK_00740 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
CADDLEGK_00741 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CADDLEGK_00742 3.2e-124 ftsE D cell division ATP-binding protein FtsE
CADDLEGK_00743 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CADDLEGK_00744 2.3e-201 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CADDLEGK_00745 6.2e-154 yjjH S Calcineurin-like phosphoesterase
CADDLEGK_00746 4.2e-130 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CADDLEGK_00747 0.0 pacL 3.6.3.8 P cation transport ATPase
CADDLEGK_00748 5.3e-68 ywiB S Domain of unknown function (DUF1934)
CADDLEGK_00749 3.7e-108 XK27_00120 2.4.2.3 F Phosphorylase superfamily
CADDLEGK_00750 2e-155 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
CADDLEGK_00751 2e-146 yidA S hydrolases of the HAD superfamily
CADDLEGK_00752 4.1e-207 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
CADDLEGK_00753 1.3e-57 S Protein of unknown function (DUF454)
CADDLEGK_00754 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
CADDLEGK_00755 1e-235 vicK 2.7.13.3 T Histidine kinase
CADDLEGK_00756 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CADDLEGK_00757 1.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
CADDLEGK_00758 3.8e-148 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CADDLEGK_00759 1.9e-116 gltJ P ABC transporter (Permease
CADDLEGK_00760 2.9e-111 tcyB_2 P ABC transporter (permease)
CADDLEGK_00761 1e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
CADDLEGK_00762 7.5e-144 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CADDLEGK_00763 1.9e-116 gltJ P ABC transporter (Permease
CADDLEGK_00764 2.9e-111 tcyB_2 P ABC transporter (permease)
CADDLEGK_00765 2.7e-152 endA F DNA RNA non-specific endonuclease
CADDLEGK_00766 2.5e-26 epuA S DNA-directed RNA polymerase subunit beta
CADDLEGK_00767 2e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CADDLEGK_00769 2e-208 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
CADDLEGK_00770 5.5e-250 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
CADDLEGK_00772 1.7e-137
CADDLEGK_00773 1.1e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CADDLEGK_00774 2.6e-65 S ABC-2 family transporter protein
CADDLEGK_00775 6.5e-103 V ABC transporter, ATP-binding protein
CADDLEGK_00776 2.8e-31 S Putative zincin peptidase
CADDLEGK_00778 9.8e-13 yydH S Peptidase M50
CADDLEGK_00781 1.8e-142 ycaO S YcaO cyclodehydratase, ATP-ad Mg2+-binding
CADDLEGK_00782 6.4e-99 K Transcriptional regulator C-terminal region
CADDLEGK_00783 3.8e-187 M Pilin isopeptide linkage domain protein
CADDLEGK_00784 6e-25 XK27_02070 S nitroreductase
CADDLEGK_00785 1.4e-150 1.13.11.2 S glyoxalase
CADDLEGK_00786 6.8e-75 ywnA K Transcriptional regulator
CADDLEGK_00787 6.3e-154 E Alpha/beta hydrolase of unknown function (DUF915)
CADDLEGK_00788 9.3e-226 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CADDLEGK_00789 3.7e-168 bcrA V abc transporter atp-binding protein
CADDLEGK_00790 8.1e-129 S ABC-2 family transporter protein
CADDLEGK_00791 3.4e-131 T PhoQ Sensor
CADDLEGK_00792 1.1e-124 T Xre family transcriptional regulator
CADDLEGK_00793 8.3e-111 drgA C nitroreductase
CADDLEGK_00794 2.2e-109 yoaK S Protein of unknown function (DUF1275)
CADDLEGK_00795 7.6e-39 DJ nuclease activity
CADDLEGK_00796 3.2e-30 XK27_10490
CADDLEGK_00797 3.5e-157 yvgN C reductase
CADDLEGK_00798 1.2e-211 S Tetratricopeptide repeat
CADDLEGK_00799 0.0 lacL 3.2.1.23 G -beta-galactosidase
CADDLEGK_00800 0.0 lacS G transporter
CADDLEGK_00801 1.5e-194 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CADDLEGK_00802 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CADDLEGK_00803 1.5e-283 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
CADDLEGK_00804 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CADDLEGK_00805 3.9e-150 galR K Transcriptional regulator
CADDLEGK_00806 4.2e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
CADDLEGK_00807 3.6e-26 L Transposase
CADDLEGK_00808 1e-93 cvpA S toxin biosynthetic process
CADDLEGK_00809 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CADDLEGK_00810 5.9e-155 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CADDLEGK_00811 2.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CADDLEGK_00812 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CADDLEGK_00813 3.7e-46 azlD S branched-chain amino acid
CADDLEGK_00814 3.9e-114 azlC E AzlC protein
CADDLEGK_00815 8.2e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CADDLEGK_00816 2.6e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CADDLEGK_00817 4.2e-116 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
CADDLEGK_00818 2.5e-33 ykzG S Belongs to the UPF0356 family
CADDLEGK_00819 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CADDLEGK_00820 3.3e-115 pscB M CHAP domain protein
CADDLEGK_00821 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
CADDLEGK_00822 2.5e-62 glnR K Transcriptional regulator
CADDLEGK_00823 3e-87 S Fusaric acid resistance protein-like
CADDLEGK_00824 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CADDLEGK_00825 7.1e-14
CADDLEGK_00826 7.9e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CADDLEGK_00827 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CADDLEGK_00828 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CADDLEGK_00829 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CADDLEGK_00830 4e-142 purR 2.4.2.7 F operon repressor
CADDLEGK_00831 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
CADDLEGK_00832 1.6e-169 rmuC S RmuC domain protein
CADDLEGK_00833 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
CADDLEGK_00834 1.7e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CADDLEGK_00835 4e-164 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CADDLEGK_00837 3.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CADDLEGK_00838 3.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CADDLEGK_00839 8.2e-10 T Histidine kinase
CADDLEGK_00840 1e-142 tatD L Hydrolase, tatd
CADDLEGK_00841 1.6e-73 yccU S CoA-binding protein
CADDLEGK_00842 2.4e-50 trxA O Belongs to the thioredoxin family
CADDLEGK_00843 1.5e-141 S Macro domain protein
CADDLEGK_00844 1e-34 ykuJ S protein conserved in bacteria
CADDLEGK_00845 3.7e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CADDLEGK_00846 0.0 clpE O Belongs to the ClpA ClpB family
CADDLEGK_00847 3e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
CADDLEGK_00848 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
CADDLEGK_00849 1e-176 S oxidoreductase
CADDLEGK_00850 4.4e-118 M Pfam SNARE associated Golgi protein
CADDLEGK_00851 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
CADDLEGK_00854 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
CADDLEGK_00857 4.8e-16 S Protein of unknown function (DUF2969)
CADDLEGK_00858 2.6e-199 ilvE 2.6.1.42 E Aminotransferase
CADDLEGK_00859 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CADDLEGK_00860 6.8e-54 S CAAX amino terminal protease family protein
CADDLEGK_00861 5.4e-134 aadK G adenylyltransferase
CADDLEGK_00862 5.9e-64 1.1.1.25, 2.3.1.128, 4.2.1.10 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CADDLEGK_00863 9.2e-38
CADDLEGK_00864 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CADDLEGK_00865 1.8e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CADDLEGK_00866 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
CADDLEGK_00867 2.2e-30 S Domain of unknown function (DUF1912)
CADDLEGK_00868 1.2e-174 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
CADDLEGK_00869 1.5e-250 mmuP E amino acid
CADDLEGK_00870 1.1e-275 2.7.7.49 L Reverse transcriptase (RNA-dependent DNA polymerase)
CADDLEGK_00871 8.7e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
CADDLEGK_00872 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CADDLEGK_00873 9.7e-22
CADDLEGK_00874 5.8e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CADDLEGK_00875 3.8e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CADDLEGK_00876 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CADDLEGK_00877 4.1e-09 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CADDLEGK_00878 4.8e-252 cycA E permease
CADDLEGK_00879 1.3e-38 ynzC S UPF0291 protein
CADDLEGK_00880 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CADDLEGK_00881 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CADDLEGK_00882 1.4e-218 S membrane
CADDLEGK_00883 6.8e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CADDLEGK_00884 2e-294 nptA P COG1283 Na phosphate symporter
CADDLEGK_00885 1.2e-114 3.4.17.14, 3.5.1.28 NU amidase activity
CADDLEGK_00886 1e-74 S Bacterial inner membrane protein
CADDLEGK_00887 5e-140 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
CADDLEGK_00888 1.3e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
CADDLEGK_00889 1.6e-52 glnB K Belongs to the P(II) protein family
CADDLEGK_00890 4.3e-228 amt P Ammonium Transporter
CADDLEGK_00891 1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CADDLEGK_00892 1.2e-54 yabA L Involved in initiation control of chromosome replication
CADDLEGK_00893 2.2e-132 yaaT S stage 0 sporulation protein
CADDLEGK_00894 5.1e-159 holB 2.7.7.7 L dna polymerase iii
CADDLEGK_00895 2.7e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CADDLEGK_00897 9.5e-33 blpT
CADDLEGK_00901 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CADDLEGK_00902 8.4e-168 corA P COG0598 Mg2 and Co2 transporters
CADDLEGK_00903 2.6e-123 XK27_01040 S Protein of unknown function (DUF1129)
CADDLEGK_00905 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CADDLEGK_00906 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CADDLEGK_00907 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
CADDLEGK_00908 1.5e-42 XK27_05745
CADDLEGK_00909 6.1e-229 mutY L A G-specific adenine glycosylase
CADDLEGK_00911 4.8e-07
CADDLEGK_00912 1.3e-37
CADDLEGK_00913 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CADDLEGK_00914 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CADDLEGK_00918 6.2e-120 yoaK S Protein of unknown function (DUF1275)
CADDLEGK_00919 4.8e-85 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CADDLEGK_00920 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
CADDLEGK_00921 1.9e-133 parB K Belongs to the ParB family
CADDLEGK_00922 1e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CADDLEGK_00923 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CADDLEGK_00924 1.1e-29 yyzM S Protein conserved in bacteria
CADDLEGK_00925 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CADDLEGK_00926 2e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CADDLEGK_00927 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CADDLEGK_00928 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CADDLEGK_00929 3e-60 divIC D Septum formation initiator
CADDLEGK_00931 4.8e-238 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
CADDLEGK_00932 5.5e-231 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CADDLEGK_00933 5.9e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CADDLEGK_00934 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CADDLEGK_00935 8.4e-186 D nuclear chromosome segregation
CADDLEGK_00936 9.5e-85 V VanZ like family
CADDLEGK_00937 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CADDLEGK_00938 3e-191 yhjX P Major Facilitator
CADDLEGK_00939 2.2e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
CADDLEGK_00940 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CADDLEGK_00941 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CADDLEGK_00942 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CADDLEGK_00943 2.6e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CADDLEGK_00944 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CADDLEGK_00945 5.9e-82 nrdI F Belongs to the NrdI family
CADDLEGK_00946 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CADDLEGK_00947 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CADDLEGK_00948 1.2e-218 metE 2.1.1.14 E Methionine synthase
CADDLEGK_00949 2.4e-151 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CADDLEGK_00950 4.1e-75 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CADDLEGK_00951 9.5e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
CADDLEGK_00953 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CADDLEGK_00954 1.4e-167 XK27_01785 S cog cog1284
CADDLEGK_00955 1.5e-124 yaaA S Belongs to the UPF0246 family
CADDLEGK_00956 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CADDLEGK_00957 2e-91 XK27_10930 K acetyltransferase
CADDLEGK_00958 7.5e-14
CADDLEGK_00959 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CADDLEGK_00960 7.5e-289 ccs S the current gene model (or a revised gene model) may contain a frame shift
CADDLEGK_00961 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CADDLEGK_00962 1e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CADDLEGK_00963 1.3e-176 prmA J Ribosomal protein L11 methyltransferase
CADDLEGK_00964 4.2e-75 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
CADDLEGK_00965 9.3e-83 XK27_03960 S Protein of unknown function (DUF3013)
CADDLEGK_00966 9.8e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CADDLEGK_00967 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CADDLEGK_00968 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CADDLEGK_00969 4e-139 ykuT M mechanosensitive ion channel
CADDLEGK_00970 1.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CADDLEGK_00971 3.4e-14 rpmH J Ribosomal protein L34
CADDLEGK_00972 1.5e-103 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
CADDLEGK_00973 2e-106 K Transcriptional regulator
CADDLEGK_00974 1.3e-180 jag S RNA-binding protein
CADDLEGK_00975 1.3e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CADDLEGK_00976 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CADDLEGK_00977 3.3e-269 argH 4.3.2.1 E Argininosuccinate lyase
CADDLEGK_00978 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CADDLEGK_00979 3e-187 adhP 1.1.1.1 C alcohol dehydrogenase
CADDLEGK_00980 6e-45
CADDLEGK_00981 1.4e-49
CADDLEGK_00982 1.5e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CADDLEGK_00983 7.9e-157 aatB ET ABC transporter substrate-binding protein
CADDLEGK_00984 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
CADDLEGK_00985 1.4e-105 artQ P ABC transporter (Permease
CADDLEGK_00986 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
CADDLEGK_00987 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CADDLEGK_00988 2.9e-165 cpsY K Transcriptional regulator
CADDLEGK_00989 1.3e-128 mur1 3.4.17.14, 3.5.1.28 NU muramidase
CADDLEGK_00990 2.1e-169 yeiH S Membrane
CADDLEGK_00992 2.6e-09
CADDLEGK_00993 5.6e-294 adcA P Belongs to the bacterial solute-binding protein 9 family
CADDLEGK_00994 7.1e-147 XK27_10720 D peptidase activity
CADDLEGK_00995 4e-275 pepD E Dipeptidase
CADDLEGK_00996 2.2e-160 whiA K May be required for sporulation
CADDLEGK_00997 1.4e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CADDLEGK_00998 1.6e-163 rapZ S Displays ATPase and GTPase activities
CADDLEGK_00999 1.4e-136 yejC S cyclic nucleotide-binding protein
CADDLEGK_01000 5.6e-201 D nuclear chromosome segregation
CADDLEGK_01001 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
CADDLEGK_01002 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CADDLEGK_01003 3.3e-82 queD 4.1.2.50, 4.2.3.12 H synthase
CADDLEGK_01004 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CADDLEGK_01005 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
CADDLEGK_01006 1.4e-18
CADDLEGK_01007 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
CADDLEGK_01008 1e-210 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CADDLEGK_01009 1.5e-80 ypmB S Protein conserved in bacteria
CADDLEGK_01010 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CADDLEGK_01011 5.8e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
CADDLEGK_01012 1.2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
CADDLEGK_01013 1.9e-176 yufP S Belongs to the binding-protein-dependent transport system permease family
CADDLEGK_01014 2.9e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
CADDLEGK_01015 4.7e-191 tcsA S membrane
CADDLEGK_01016 1.8e-66 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CADDLEGK_01017 7.9e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CADDLEGK_01018 5.6e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
CADDLEGK_01019 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
CADDLEGK_01020 2.8e-171 coaA 2.7.1.33 F Pantothenic acid kinase
CADDLEGK_01021 1e-29 rpsT J Binds directly to 16S ribosomal RNA
CADDLEGK_01022 9.5e-240 T PhoQ Sensor
CADDLEGK_01023 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CADDLEGK_01024 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CADDLEGK_01025 1e-114 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
CADDLEGK_01026 7.4e-92 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CADDLEGK_01027 7.1e-93 panT S ECF transporter, substrate-specific component
CADDLEGK_01028 2.9e-91 panT S Psort location CytoplasmicMembrane, score
CADDLEGK_01029 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
CADDLEGK_01030 1.6e-165 metF 1.5.1.20 E reductase
CADDLEGK_01031 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CADDLEGK_01033 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
CADDLEGK_01034 0.0 3.6.3.8 P cation transport ATPase
CADDLEGK_01035 1.5e-244 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CADDLEGK_01036 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CADDLEGK_01037 3.1e-234 dltB M Membrane protein involved in D-alanine export
CADDLEGK_01038 1.3e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CADDLEGK_01039 0.0 XK27_10035 V abc transporter atp-binding protein
CADDLEGK_01040 9.1e-293 yfiB1 V abc transporter atp-binding protein
CADDLEGK_01041 7e-99 pvaA M lytic transglycosylase activity
CADDLEGK_01042 2.5e-178 ndpA S 37-kD nucleoid-associated bacterial protein
CADDLEGK_01043 6.2e-235 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CADDLEGK_01044 1.3e-108 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CADDLEGK_01045 3.1e-150 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CADDLEGK_01046 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CADDLEGK_01047 2.8e-108 tdk 2.7.1.21 F thymidine kinase
CADDLEGK_01048 2.1e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CADDLEGK_01049 1.5e-154 gst O Glutathione S-transferase
CADDLEGK_01050 1e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
CADDLEGK_01051 3.4e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CADDLEGK_01052 4.4e-45 rpmE2 J 50S ribosomal protein L31
CADDLEGK_01053 2.3e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
CADDLEGK_01054 5.8e-164 ypuA S secreted protein
CADDLEGK_01055 2.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
CADDLEGK_01056 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
CADDLEGK_01057 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CADDLEGK_01058 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CADDLEGK_01059 1.4e-256 noxE P NADH oxidase
CADDLEGK_01060 1.5e-294 yfmM S abc transporter atp-binding protein
CADDLEGK_01061 6.1e-83 XK27_01265 S ECF-type riboflavin transporter, S component
CADDLEGK_01062 5.9e-152 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
CADDLEGK_01063 3.3e-86 S ECF-type riboflavin transporter, S component
CADDLEGK_01065 1.1e-236 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CADDLEGK_01066 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
CADDLEGK_01068 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CADDLEGK_01069 1.7e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CADDLEGK_01070 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CADDLEGK_01071 2.9e-22 WQ51_00220 K Helix-turn-helix domain
CADDLEGK_01072 1e-93 S Protein of unknown function (DUF3278)
CADDLEGK_01073 0.0 smc D Required for chromosome condensation and partitioning
CADDLEGK_01074 7.1e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CADDLEGK_01075 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CADDLEGK_01076 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CADDLEGK_01077 1.8e-124 alkD L Dna alkylation repair
CADDLEGK_01078 1.4e-300 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CADDLEGK_01079 1.1e-92 pat 2.3.1.183 M acetyltransferase
CADDLEGK_01080 2.9e-273 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CADDLEGK_01081 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CADDLEGK_01082 8.2e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
CADDLEGK_01083 2.5e-121 sdaAB 4.3.1.17 E L-serine dehydratase
CADDLEGK_01084 1.4e-148 sdaAA 4.3.1.17 E L-serine dehydratase
CADDLEGK_01085 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
CADDLEGK_01086 4.8e-160 yjlA EG membrane
CADDLEGK_01087 2.1e-80 3.4.21.89 S RDD family
CADDLEGK_01088 1.6e-163 K sequence-specific DNA binding
CADDLEGK_01089 4e-153 V ABC transporter, ATP-binding protein
CADDLEGK_01090 7.2e-103 S ABC-2 family transporter protein
CADDLEGK_01091 2.2e-165 K sequence-specific DNA binding
CADDLEGK_01092 2.7e-51 ywrO S general stress protein
CADDLEGK_01093 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
CADDLEGK_01094 1.2e-77 yfiQ K Acetyltransferase (GNAT) domain
CADDLEGK_01095 5.6e-141 S ABC-2 family transporter protein
CADDLEGK_01096 1.2e-141 S ABC-2 family transporter protein
CADDLEGK_01097 6.1e-185 S AAA domain, putative AbiEii toxin, Type IV TA system
CADDLEGK_01098 3.7e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CADDLEGK_01099 1.1e-187 desK 2.7.13.3 T Histidine kinase
CADDLEGK_01100 1.2e-132 yvfS V ABC-2 type transporter
CADDLEGK_01101 1.4e-156 XK27_09825 V 'abc transporter, ATP-binding protein
CADDLEGK_01104 6.7e-165 yocS S Transporter
CADDLEGK_01105 5.8e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
CADDLEGK_01106 3.8e-115 yvfS V Transporter
CADDLEGK_01107 6.5e-154 XK27_09825 V abc transporter atp-binding protein
CADDLEGK_01108 1.2e-14 liaI KT membrane
CADDLEGK_01109 1.8e-31 liaI KT membrane
CADDLEGK_01110 6.1e-93 XK27_05000 S metal cluster binding
CADDLEGK_01111 0.0 V ABC transporter (permease)
CADDLEGK_01112 7.1e-133 macB2 V ABC transporter, ATP-binding protein
CADDLEGK_01113 5.7e-151 T Histidine kinase
CADDLEGK_01114 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CADDLEGK_01115 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CADDLEGK_01116 2.5e-223 pbuX F xanthine permease
CADDLEGK_01117 2e-60 pdxH S pyridoxamine 5'-phosphate oxidase
CADDLEGK_01118 6.9e-271 V (ABC) transporter
CADDLEGK_01119 2.9e-143 K sequence-specific DNA binding
CADDLEGK_01120 5.9e-239 norM V Multidrug efflux pump
CADDLEGK_01122 2e-180 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CADDLEGK_01123 3.1e-232 brnQ E Component of the transport system for branched-chain amino acids
CADDLEGK_01124 3.3e-180 manA 5.3.1.8 G mannose-6-phosphate isomerase
CADDLEGK_01125 1.8e-59 S Protein of unknown function (DUF3290)
CADDLEGK_01126 1.5e-107 S Protein of unknown function (DUF421)
CADDLEGK_01127 1.4e-16 csbD S CsbD-like
CADDLEGK_01128 1.8e-114 S Carbohydrate-binding domain-containing protein Cthe_2159
CADDLEGK_01129 2.3e-51 XK27_01300 P Protein conserved in bacteria
CADDLEGK_01130 1.6e-215 yfnA E amino acid
CADDLEGK_01131 0.0 S dextransucrase activity
CADDLEGK_01132 4e-60 M Putative cell wall binding repeat
CADDLEGK_01134 1.3e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
CADDLEGK_01135 6e-115 yxeN P ABC transporter, permease protein
CADDLEGK_01136 9.1e-111 ytmL P ABC transporter (Permease
CADDLEGK_01137 4e-164 ET ABC transporter substrate-binding protein
CADDLEGK_01138 3.4e-175 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
CADDLEGK_01139 6.2e-82 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
CADDLEGK_01140 1.5e-42 S Sugar efflux transporter for intercellular exchange
CADDLEGK_01141 2.6e-203 P FtsX-like permease family
CADDLEGK_01142 5.4e-124 V abc transporter atp-binding protein
CADDLEGK_01143 3.6e-97 K WHG domain
CADDLEGK_01144 1.7e-168 ydhF S Aldo keto reductase
CADDLEGK_01146 9.5e-18 3.2.1.51 GH95 U LPXTG cell wall anchor motif
CADDLEGK_01148 5.8e-115 V ATPases associated with a variety of cellular activities
CADDLEGK_01149 1.1e-119
CADDLEGK_01150 1.8e-232 2.7.13.3 T GHKL domain
CADDLEGK_01151 2.6e-135 agrA KT Response regulator of the LytR AlgR family
CADDLEGK_01153 1.8e-33 3.4.24.40 U Large extracellular alpha-helical protein
CADDLEGK_01155 6.6e-08
CADDLEGK_01156 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
CADDLEGK_01157 1.4e-78 feoA P FeoA domain protein
CADDLEGK_01158 6.4e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
CADDLEGK_01159 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
CADDLEGK_01160 6.7e-61 L thioesterase
CADDLEGK_01161 1e-51 bta 1.8.1.8 CO cell redox homeostasis
CADDLEGK_01163 6.9e-215 L Transposase IS116 IS110 IS902
CADDLEGK_01165 3.9e-87 sigH K DNA-templated transcription, initiation
CADDLEGK_01166 2.2e-15 L PFAM Integrase, catalytic core
CADDLEGK_01167 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CADDLEGK_01168 2e-83 comFC K competence protein
CADDLEGK_01169 2.6e-247 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CADDLEGK_01170 3.2e-107 yvyE 3.4.13.9 S YigZ family
CADDLEGK_01171 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CADDLEGK_01172 3e-111 acuB S CBS domain
CADDLEGK_01173 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
CADDLEGK_01174 3.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
CADDLEGK_01175 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
CADDLEGK_01176 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
CADDLEGK_01177 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
CADDLEGK_01178 1.9e-46 ylbG S UPF0298 protein
CADDLEGK_01179 1.4e-72 ylbF S Belongs to the UPF0342 family
CADDLEGK_01180 1.1e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CADDLEGK_01181 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CADDLEGK_01182 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
CADDLEGK_01183 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
CADDLEGK_01184 1.3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CADDLEGK_01185 1.1e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
CADDLEGK_01186 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
CADDLEGK_01187 2.2e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
CADDLEGK_01188 4.9e-268 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CADDLEGK_01189 1.3e-99 yvdD 3.2.2.10 S Belongs to the LOG family
CADDLEGK_01190 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CADDLEGK_01191 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CADDLEGK_01192 8e-42 ylxQ J ribosomal protein
CADDLEGK_01193 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
CADDLEGK_01194 2.4e-196 nusA K Participates in both transcription termination and antitermination
CADDLEGK_01195 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
CADDLEGK_01196 2.8e-211 brpA K Transcriptional
CADDLEGK_01197 6e-91 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
CADDLEGK_01198 4.7e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
CADDLEGK_01199 2.1e-247 pbuO S permease
CADDLEGK_01200 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
CADDLEGK_01201 8.7e-136 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
CADDLEGK_01202 6.2e-169 manL 2.7.1.191 G pts system
CADDLEGK_01203 5.7e-133 manY G pts system
CADDLEGK_01204 3.4e-158 manN G PTS system mannose fructose sorbose family IID component
CADDLEGK_01205 2e-67 manO S Protein conserved in bacteria
CADDLEGK_01206 4.9e-174 manL 2.7.1.191 G pts system
CADDLEGK_01207 7.2e-115 manM G pts system
CADDLEGK_01208 3.1e-167 manN G PTS system mannose fructose sorbose family IID component
CADDLEGK_01209 2.5e-62 manO S protein conserved in bacteria
CADDLEGK_01210 3.1e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CADDLEGK_01211 2.2e-111
CADDLEGK_01212 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CADDLEGK_01213 1.5e-166 dnaI L Primosomal protein DnaI
CADDLEGK_01214 6.1e-216 dnaB L Replication initiation and membrane attachment
CADDLEGK_01215 1.4e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CADDLEGK_01216 1.2e-280 T PhoQ Sensor
CADDLEGK_01217 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CADDLEGK_01218 1.8e-90 yceD K metal-binding, possibly nucleic acid-binding protein
CADDLEGK_01219 2.6e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
CADDLEGK_01220 9.5e-237 P COG0168 Trk-type K transport systems, membrane components
CADDLEGK_01221 4.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
CADDLEGK_01222 2e-149 cbiQ P cobalt transport
CADDLEGK_01223 0.0 ykoD P abc transporter atp-binding protein
CADDLEGK_01224 8e-94 S UPF0397 protein
CADDLEGK_01225 1.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
CADDLEGK_01226 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CADDLEGK_01227 1.2e-99 metI P ABC transporter (Permease
CADDLEGK_01228 4.6e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CADDLEGK_01229 1.2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
CADDLEGK_01230 3.5e-163 metQ M Belongs to the NlpA lipoprotein family
CADDLEGK_01231 6.3e-138 ET ABC transporter substrate-binding protein
CADDLEGK_01232 5.3e-130 cbiO P ABC transporter
CADDLEGK_01233 1.1e-136 P cobalt transport protein
CADDLEGK_01234 1.3e-176 cbiM P biosynthesis protein CbiM
CADDLEGK_01235 4e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
CADDLEGK_01236 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CADDLEGK_01237 3.4e-129 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
CADDLEGK_01238 1.9e-77 ureE O enzyme active site formation
CADDLEGK_01239 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CADDLEGK_01240 5.1e-53 ureB 3.5.1.5 E Belongs to the urease beta subunit family
CADDLEGK_01241 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
CADDLEGK_01242 1.8e-95 ureI S AmiS/UreI family transporter
CADDLEGK_01243 2.5e-237 S Domain of unknown function (DUF4173)
CADDLEGK_01244 8.7e-51 yhaI L Membrane
CADDLEGK_01245 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CADDLEGK_01246 3.9e-154 K sequence-specific DNA binding
CADDLEGK_01247 2.8e-106 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
CADDLEGK_01248 5.5e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CADDLEGK_01249 5.1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CADDLEGK_01250 2.6e-247 trkA P Potassium transporter peripheral membrane component
CADDLEGK_01251 4.2e-259 trkH P Cation transport protein
CADDLEGK_01252 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
CADDLEGK_01253 4.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CADDLEGK_01254 3.8e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CADDLEGK_01255 2.6e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CADDLEGK_01256 7.2e-133 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
CADDLEGK_01257 8.3e-87 ykuL S CBS domain
CADDLEGK_01258 3.9e-98 XK27_09740 S Phosphoesterase
CADDLEGK_01259 5.1e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CADDLEGK_01260 5.8e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CADDLEGK_01261 1.6e-36 yneF S UPF0154 protein
CADDLEGK_01262 1.8e-90 K transcriptional regulator
CADDLEGK_01263 6.2e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CADDLEGK_01264 9.3e-12 ycdA S Domain of unknown function (DUF4352)
CADDLEGK_01265 8.5e-101 ybhL S Belongs to the BI1 family
CADDLEGK_01266 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
CADDLEGK_01267 8.7e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CADDLEGK_01268 9.2e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CADDLEGK_01269 3.4e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CADDLEGK_01270 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CADDLEGK_01271 4.2e-302 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CADDLEGK_01272 6.5e-87 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
CADDLEGK_01273 1.2e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CADDLEGK_01274 9.6e-23
CADDLEGK_01275 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
CADDLEGK_01276 2.3e-276 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
CADDLEGK_01277 1.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CADDLEGK_01278 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CADDLEGK_01279 5.8e-94 ypsA S Belongs to the UPF0398 family
CADDLEGK_01280 8.1e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CADDLEGK_01281 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CADDLEGK_01282 1.6e-257 pepC 3.4.22.40 E aminopeptidase
CADDLEGK_01283 1.1e-77 yhaI S Protein of unknown function (DUF805)
CADDLEGK_01284 4.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CADDLEGK_01285 1.9e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CADDLEGK_01286 1.6e-217 macB_2 V FtsX-like permease family
CADDLEGK_01287 3.3e-121 yhcA V abc transporter atp-binding protein
CADDLEGK_01288 5.6e-124 mta K Transcriptional
CADDLEGK_01289 8.9e-32 S Protein of unknown function (DUF3021)
CADDLEGK_01290 9e-75 K COG3279 Response regulator of the LytR AlgR family
CADDLEGK_01291 5.3e-129 cylB V ABC-2 type transporter
CADDLEGK_01292 6.6e-151 cylA V abc transporter atp-binding protein
CADDLEGK_01293 7.8e-25 yjdF S Protein of unknown function (DUF2992)
CADDLEGK_01294 4e-234 S COG1073 Hydrolases of the alpha beta superfamily
CADDLEGK_01295 3.8e-73 K transcriptional
CADDLEGK_01296 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CADDLEGK_01297 1e-134 glcR K transcriptional regulator (DeoR family)
CADDLEGK_01298 7.8e-146 cof S Sucrose-6F-phosphate phosphohydrolase
CADDLEGK_01299 3e-67 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
CADDLEGK_01300 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
CADDLEGK_01301 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
CADDLEGK_01302 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CADDLEGK_01303 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CADDLEGK_01304 5.2e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CADDLEGK_01305 5.8e-55 S TM2 domain
CADDLEGK_01306 5.5e-44
CADDLEGK_01308 2.2e-285 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CADDLEGK_01309 1.9e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CADDLEGK_01310 1.4e-142 cmpC S abc transporter atp-binding protein
CADDLEGK_01311 0.0 WQ51_06230 S ABC transporter
CADDLEGK_01312 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CADDLEGK_01313 6.5e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CADDLEGK_01314 2.1e-143 cdsA 2.7.7.41 S Belongs to the CDS family
CADDLEGK_01315 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CADDLEGK_01316 1.7e-46 yajC U protein transport
CADDLEGK_01317 6.1e-126 yeeN K transcriptional regulatory protein
CADDLEGK_01318 8.3e-277 V ABC transporter
CADDLEGK_01319 2.3e-151 Z012_04635 K sequence-specific DNA binding
CADDLEGK_01320 2.4e-256 pgi 5.3.1.9 G Belongs to the GPI family
CADDLEGK_01321 3.1e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
CADDLEGK_01322 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CADDLEGK_01323 5.3e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
CADDLEGK_01324 5.6e-128 adcB P ABC transporter (Permease
CADDLEGK_01325 5.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
CADDLEGK_01326 1.6e-71 adcR K transcriptional
CADDLEGK_01327 6.2e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CADDLEGK_01328 1e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CADDLEGK_01329 4.7e-26
CADDLEGK_01330 2.9e-273 sufB O assembly protein SufB
CADDLEGK_01331 6.8e-72 nifU C SUF system FeS assembly protein, NifU family
CADDLEGK_01332 8.6e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CADDLEGK_01333 2e-233 sufD O assembly protein SufD
CADDLEGK_01334 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CADDLEGK_01335 1.5e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
CADDLEGK_01336 2.7e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CADDLEGK_01337 8.3e-18 S Protein of unknown function (DUF3021)
CADDLEGK_01338 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CADDLEGK_01339 4.2e-273 glnP P ABC transporter
CADDLEGK_01340 2.2e-123 glnQ E abc transporter atp-binding protein
CADDLEGK_01341 1.1e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
CADDLEGK_01342 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
CADDLEGK_01343 3.4e-169 S CAAX amino terminal protease family protein
CADDLEGK_01345 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CADDLEGK_01346 2e-88 MA20_25245 K Gnat family
CADDLEGK_01347 1.8e-113 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
CADDLEGK_01348 7.6e-21 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CADDLEGK_01349 3.7e-84 mutT 3.6.1.55 F Nudix family
CADDLEGK_01350 9.3e-139 ET ABC transporter
CADDLEGK_01351 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
CADDLEGK_01352 2.3e-209 arcT 2.6.1.1 E Aminotransferase
CADDLEGK_01353 2.1e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
CADDLEGK_01354 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CADDLEGK_01355 9.8e-51 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CADDLEGK_01356 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CADDLEGK_01357 2.3e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CADDLEGK_01358 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
CADDLEGK_01359 3.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
CADDLEGK_01360 4.3e-267 S Glucosyl transferase GtrII
CADDLEGK_01361 1.7e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CADDLEGK_01362 1.2e-167 amrA S polysaccharide biosynthetic process
CADDLEGK_01363 1.6e-140 M Glycosyl transferase family 8
CADDLEGK_01364 7e-127 arnC M group 2 family protein
CADDLEGK_01365 1.8e-46 S Uncharacterized conserved protein (DUF2304)
CADDLEGK_01366 1.1e-152 2.4.1.60 S Glycosyltransferase group 2 family protein
CADDLEGK_01367 4.1e-117
CADDLEGK_01368 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
CADDLEGK_01369 1.7e-221 M Psort location CytoplasmicMembrane, score
CADDLEGK_01370 6.9e-234 GT4 M transferase activity, transferring glycosyl groups
CADDLEGK_01371 1.5e-259 S Glucosyl transferase GtrII
CADDLEGK_01372 5.4e-225 rgpA GT4 M Domain of unknown function (DUF1972)
CADDLEGK_01373 1.2e-174 rgpB GT2 M Glycosyltransferase, group 2 family protein
CADDLEGK_01374 6.8e-142 rgpC GM Transport permease protein
CADDLEGK_01375 3.3e-225 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CADDLEGK_01376 1.5e-305 rgpF M Rhamnan synthesis protein F
CADDLEGK_01377 6.7e-114 radC E Belongs to the UPF0758 family
CADDLEGK_01378 8.2e-128 puuD T peptidase C26
CADDLEGK_01379 6.2e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CADDLEGK_01380 8.2e-60 XK27_04120 S Putative amino acid metabolism
CADDLEGK_01381 1.5e-203 iscS 2.8.1.7 E Cysteine desulfurase
CADDLEGK_01382 6.6e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CADDLEGK_01383 7.8e-100 yjbK S Adenylate cyclase
CADDLEGK_01384 2e-118 yjbM 2.7.6.5 S Gtp pyrophosphokinase
CADDLEGK_01385 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CADDLEGK_01386 9.2e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
CADDLEGK_01387 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CADDLEGK_01388 0.0 amiA E ABC transporter, substrate-binding protein, family 5
CADDLEGK_01389 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
CADDLEGK_01390 4.9e-279 amiC P ABC transporter (Permease
CADDLEGK_01391 1.4e-167 amiD P ABC transporter (Permease
CADDLEGK_01392 4.6e-202 oppD P Belongs to the ABC transporter superfamily
CADDLEGK_01393 4.7e-171 oppF P Belongs to the ABC transporter superfamily
CADDLEGK_01394 9.9e-130 V Psort location CytoplasmicMembrane, score
CADDLEGK_01395 1.8e-119 skfE V abc transporter atp-binding protein
CADDLEGK_01396 5.6e-62 yvoA_1 K Transcriptional
CADDLEGK_01397 1.4e-147 supH S overlaps another CDS with the same product name
CADDLEGK_01398 2.3e-145 XK27_02985 S overlaps another CDS with the same product name
CADDLEGK_01399 1.6e-194 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CADDLEGK_01400 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CADDLEGK_01401 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
CADDLEGK_01402 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CADDLEGK_01403 8.1e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CADDLEGK_01404 8e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CADDLEGK_01405 4.8e-137 stp 3.1.3.16 T phosphatase
CADDLEGK_01406 1.4e-302 prkC 2.7.11.1 KLT serine threonine protein kinase
CADDLEGK_01407 3.8e-94 kcsA P Ion transport protein
CADDLEGK_01408 8.6e-117 yvqF S Membrane
CADDLEGK_01409 1.9e-170 vraS 2.7.13.3 T Histidine kinase
CADDLEGK_01410 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CADDLEGK_01413 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CADDLEGK_01414 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CADDLEGK_01415 1.2e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
CADDLEGK_01416 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CADDLEGK_01417 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CADDLEGK_01418 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CADDLEGK_01419 5.8e-187 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CADDLEGK_01420 4e-180 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
CADDLEGK_01421 7e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
CADDLEGK_01422 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CADDLEGK_01423 6.5e-99 2.3.1.128 K Acetyltransferase GNAT Family
CADDLEGK_01424 4.7e-285 S Protein of unknown function (DUF3114)
CADDLEGK_01426 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
CADDLEGK_01427 4e-296 V abc transporter atp-binding protein
CADDLEGK_01428 0.0 V abc transporter atp-binding protein
CADDLEGK_01429 1.9e-193 XK27_10075 S abc transporter atp-binding protein
CADDLEGK_01430 0.0 glgE 2.3.1.12, 2.4.99.16, 3.2.1.1, 3.2.1.14 GH13,GH18 M Pilin isopeptide linkage domain protein
CADDLEGK_01431 0.0 M Pilin isopeptide linkage domain protein
CADDLEGK_01432 0.0 zmpB M signal peptide protein, YSIRK family
CADDLEGK_01433 0.0 GM domain, Protein
CADDLEGK_01434 1e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CADDLEGK_01435 0.0 sbcC L ATPase involved in DNA repair
CADDLEGK_01436 3.4e-155 cat 2.3.1.28 S acetyltransferase'
CADDLEGK_01437 0.0 M family 8
CADDLEGK_01438 3.4e-147 epsH S acetyltransferase'
CADDLEGK_01439 1.2e-235 M Glycosyltransferase, family 8
CADDLEGK_01440 3.4e-288 tagE 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CADDLEGK_01441 3.3e-196 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CADDLEGK_01442 1.3e-185 nss M transferase activity, transferring glycosyl groups
CADDLEGK_01443 8.4e-237 M Glycosyltransferase, family 8
CADDLEGK_01444 5.1e-167 cpsJ M Glycosyltransferase group 2 family protein
CADDLEGK_01445 0.0 M cog cog1442
CADDLEGK_01446 3.1e-242 M family 8
CADDLEGK_01447 1.2e-163 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
CADDLEGK_01448 9.5e-310 asp1 S Accessory Sec system protein Asp1
CADDLEGK_01449 9.4e-302 asp2 3.4.11.5 S Accessory Sec system protein Asp2
CADDLEGK_01450 1.6e-68 asp3 S Accessory Sec system protein Asp3
CADDLEGK_01451 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CADDLEGK_01452 3.9e-13 S Accessory secretory protein Sec Asp4
CADDLEGK_01453 7e-12 S Accessory secretory protein Sec, Asp5
CADDLEGK_01455 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CADDLEGK_01456 0.0 comEC S Competence protein ComEC
CADDLEGK_01457 1.1e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
CADDLEGK_01458 9.8e-143 plsC 2.3.1.51 I Acyltransferase
CADDLEGK_01459 2.1e-153 nodB3 G deacetylase
CADDLEGK_01460 8.7e-139 yabB 2.1.1.223 L Methyltransferase
CADDLEGK_01461 1.1e-40 yazA L endonuclease containing a URI domain
CADDLEGK_01462 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CADDLEGK_01463 8.1e-152 corA P CorA-like protein
CADDLEGK_01464 3.3e-62 yjqA S Bacterial PH domain
CADDLEGK_01465 7.8e-100 thiT S Thiamine transporter
CADDLEGK_01466 1.8e-153 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CADDLEGK_01467 1.9e-193 yjbB G Permeases of the major facilitator superfamily
CADDLEGK_01468 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CADDLEGK_01470 2.4e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
CADDLEGK_01471 3.2e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CADDLEGK_01475 2.2e-154 cjaA ET ABC transporter substrate-binding protein
CADDLEGK_01476 5.2e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
CADDLEGK_01477 8.6e-106 P ABC transporter (Permease
CADDLEGK_01478 3e-114 papP P ABC transporter (Permease
CADDLEGK_01479 1e-190 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CADDLEGK_01480 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
CADDLEGK_01481 0.0 copA 3.6.3.54 P P-type ATPase
CADDLEGK_01482 6.8e-72 copY K negative regulation of transcription, DNA-templated
CADDLEGK_01483 6.4e-157 EGP Major facilitator Superfamily
CADDLEGK_01484 7.8e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CADDLEGK_01485 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CADDLEGK_01486 1.4e-96 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
CADDLEGK_01487 9.4e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
CADDLEGK_01488 5.6e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CADDLEGK_01489 1.4e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
CADDLEGK_01490 3.4e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CADDLEGK_01491 1.2e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
CADDLEGK_01492 3.5e-120 yujD V lipoprotein transporter activity
CADDLEGK_01493 0.0 S bacteriocin-associated integral membrane protein
CADDLEGK_01494 2.1e-19 S Bacteriocin (Lactococcin_972)
CADDLEGK_01495 4.3e-59
CADDLEGK_01496 0.0 ctpE P E1-E2 ATPase
CADDLEGK_01497 4.1e-44
CADDLEGK_01498 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CADDLEGK_01500 1.5e-124 V abc transporter atp-binding protein
CADDLEGK_01501 0.0 V ABC transporter (Permease
CADDLEGK_01502 7.8e-121 K transcriptional regulator, MerR family
CADDLEGK_01503 9.8e-106 dnaQ 2.7.7.7 L DNA polymerase III
CADDLEGK_01504 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
CADDLEGK_01505 2.1e-63 XK27_02560 S cog cog2151
CADDLEGK_01506 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CADDLEGK_01507 4.7e-224 ytfP S Flavoprotein
CADDLEGK_01509 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CADDLEGK_01510 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
CADDLEGK_01511 2.4e-176 ecsB U Bacterial ABC transporter protein EcsB
CADDLEGK_01512 1.6e-129 ecsA V abc transporter atp-binding protein
CADDLEGK_01513 1.1e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CADDLEGK_01517 1.6e-103
CADDLEGK_01519 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
CADDLEGK_01521 3.9e-43 yoeB S Addiction module toxin, Txe YoeB family
CADDLEGK_01522 7.6e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
CADDLEGK_01523 0.0 hsdR 3.1.21.3 L COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
CADDLEGK_01524 1e-157 K SIR2-like domain
CADDLEGK_01525 4.3e-82 3.1.21.3 V Type I restriction modification DNA specificity domain
CADDLEGK_01526 0.0 2.1.1.72 V type I restriction-modification system
CADDLEGK_01527 5.3e-198 ylbM S Belongs to the UPF0348 family
CADDLEGK_01528 8.4e-139 yqeM Q Methyltransferase domain protein
CADDLEGK_01529 7.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CADDLEGK_01530 1.1e-84 entB 3.5.1.19 Q Isochorismatase family
CADDLEGK_01531 1.6e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
CADDLEGK_01532 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CADDLEGK_01533 7.7e-49 yhbY J RNA-binding protein
CADDLEGK_01534 9.2e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CADDLEGK_01535 3.3e-97 yqeG S hydrolase of the HAD superfamily
CADDLEGK_01536 1.5e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CADDLEGK_01537 3.9e-63
CADDLEGK_01538 8.2e-217 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CADDLEGK_01539 3.2e-57
CADDLEGK_01540 2.9e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
CADDLEGK_01541 2.7e-277 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
CADDLEGK_01542 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
CADDLEGK_01543 7.2e-31 S PQ loop repeat
CADDLEGK_01544 1.9e-283 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CADDLEGK_01546 8.7e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CADDLEGK_01547 6.3e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CADDLEGK_01548 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CADDLEGK_01549 1.8e-44 tagE 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
CADDLEGK_01550 7.7e-41 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CADDLEGK_01551 4.9e-224 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CADDLEGK_01552 2e-100 pncA Q isochorismatase
CADDLEGK_01553 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CADDLEGK_01554 6.9e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
CADDLEGK_01555 9e-75 XK27_03180 T universal stress protein
CADDLEGK_01557 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CADDLEGK_01558 5.1e-08 MU outer membrane autotransporter barrel domain protein
CADDLEGK_01559 8.4e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
CADDLEGK_01560 7.8e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
CADDLEGK_01561 0.0 yjcE P NhaP-type Na H and K H antiporters
CADDLEGK_01563 1e-96 ytqB 2.1.1.176 J (SAM)-dependent
CADDLEGK_01564 8.4e-184 yhcC S radical SAM protein
CADDLEGK_01565 4.2e-187 ylbL T Belongs to the peptidase S16 family
CADDLEGK_01566 1e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CADDLEGK_01567 2.9e-105 rsmD 2.1.1.171 L Methyltransferase
CADDLEGK_01568 1.7e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CADDLEGK_01569 5e-10 S Protein of unknown function (DUF4059)
CADDLEGK_01570 1.4e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
CADDLEGK_01571 6.1e-163 yxeN P ABC transporter (Permease
CADDLEGK_01572 1.9e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CADDLEGK_01573 3.3e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CADDLEGK_01574 3.6e-35
CADDLEGK_01575 9.5e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CADDLEGK_01576 0.0 pflB 2.3.1.54 C formate acetyltransferase'
CADDLEGK_01578 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
CADDLEGK_01579 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
CADDLEGK_01580 2.8e-76 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CADDLEGK_01582 1.6e-179 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
CADDLEGK_01583 3.2e-141 cppA E CppA N-terminal
CADDLEGK_01584 7e-108 V CAAX protease self-immunity
CADDLEGK_01585 1.2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
CADDLEGK_01586 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CADDLEGK_01589 2.8e-134 fasA KT Response regulator of the LytR AlgR family
CADDLEGK_01590 1e-243 fasC 2.7.13.3 T protein histidine kinase activity
CADDLEGK_01591 4.6e-209 hpk9 2.7.13.3 T protein histidine kinase activity
CADDLEGK_01592 2e-155 hpk9 2.7.13.3 T protein histidine kinase activity
CADDLEGK_01593 6.7e-232 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
CADDLEGK_01594 3.5e-274 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CADDLEGK_01595 0.0 amiA E ABC transporter, substrate-binding protein, family 5
CADDLEGK_01596 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CADDLEGK_01597 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CADDLEGK_01598 1.2e-50 S Protein of unknown function (DUF3397)
CADDLEGK_01599 3e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
CADDLEGK_01600 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
CADDLEGK_01601 1.5e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CADDLEGK_01602 3e-74 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
CADDLEGK_01603 1.2e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
CADDLEGK_01604 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
CADDLEGK_01605 7.9e-230 XK27_09615 C reductase
CADDLEGK_01606 4e-139 fnt P Formate nitrite transporter
CADDLEGK_01607 3.2e-98 XK27_08585 S Psort location CytoplasmicMembrane, score
CADDLEGK_01608 9.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CADDLEGK_01609 6.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CADDLEGK_01610 2e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
CADDLEGK_01611 2.8e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CADDLEGK_01612 7.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CADDLEGK_01613 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CADDLEGK_01614 1.8e-141 S HAD hydrolase, family IA, variant
CADDLEGK_01615 1.2e-160 rrmA 2.1.1.187 Q methyltransferase
CADDLEGK_01619 3.9e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CADDLEGK_01620 3.3e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CADDLEGK_01621 8.3e-37 yeeD O sulfur carrier activity
CADDLEGK_01622 5.8e-186 yeeE S Sulphur transport
CADDLEGK_01623 1.1e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CADDLEGK_01624 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CADDLEGK_01625 2e-08 XK27_10305 S Domain of unknown function (DUF4651)
CADDLEGK_01626 2e-202 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
CADDLEGK_01627 3.7e-129 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CADDLEGK_01628 3e-103 S CAAX amino terminal protease family protein
CADDLEGK_01630 2.1e-109 V CAAX protease self-immunity
CADDLEGK_01631 8.8e-27 lanR K sequence-specific DNA binding
CADDLEGK_01632 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CADDLEGK_01633 2.5e-175 ytxK 2.1.1.72 L DNA methylase
CADDLEGK_01634 2e-12 comGF U Putative Competence protein ComGF
CADDLEGK_01635 2e-71 comGF U Competence protein ComGF
CADDLEGK_01636 3.1e-15 NU Type II secretory pathway pseudopilin
CADDLEGK_01637 8.4e-70 cglD NU Competence protein
CADDLEGK_01638 2.2e-43 comGC U Required for transformation and DNA binding
CADDLEGK_01639 1.4e-145 cglB U protein transport across the cell outer membrane
CADDLEGK_01640 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CADDLEGK_01641 1e-68 S cog cog4699
CADDLEGK_01642 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CADDLEGK_01643 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CADDLEGK_01644 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CADDLEGK_01645 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CADDLEGK_01646 3e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CADDLEGK_01647 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
CADDLEGK_01648 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
CADDLEGK_01649 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CADDLEGK_01650 3.8e-304 yloV S kinase related to dihydroxyacetone kinase
CADDLEGK_01651 1.4e-57 asp S cog cog1302
CADDLEGK_01652 2.7e-225 norN V Mate efflux family protein
CADDLEGK_01653 3.5e-277 thrC 4.2.3.1 E Threonine synthase
CADDLEGK_01656 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CADDLEGK_01657 0.0 pepO 3.4.24.71 O Peptidase family M13
CADDLEGK_01658 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CADDLEGK_01659 3.2e-220 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CADDLEGK_01660 1.7e-49 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CADDLEGK_01661 5.1e-125 treR K trehalose operon
CADDLEGK_01662 1.9e-95 ywlG S Belongs to the UPF0340 family
CADDLEGK_01665 3.1e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
CADDLEGK_01667 3.9e-240 6.3.2.2 H gamma-glutamylcysteine synthetase
CADDLEGK_01668 4.4e-62 rplQ J ribosomal protein l17
CADDLEGK_01669 4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CADDLEGK_01670 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CADDLEGK_01671 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CADDLEGK_01672 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CADDLEGK_01673 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CADDLEGK_01674 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CADDLEGK_01675 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CADDLEGK_01676 5.7e-58 rplO J binds to the 23S rRNA
CADDLEGK_01677 1.9e-23 rpmD J ribosomal protein l30
CADDLEGK_01678 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CADDLEGK_01679 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CADDLEGK_01680 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CADDLEGK_01681 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CADDLEGK_01682 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CADDLEGK_01683 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CADDLEGK_01684 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CADDLEGK_01685 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CADDLEGK_01686 7.8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CADDLEGK_01687 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
CADDLEGK_01688 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CADDLEGK_01689 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CADDLEGK_01690 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CADDLEGK_01691 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CADDLEGK_01692 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CADDLEGK_01693 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CADDLEGK_01694 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
CADDLEGK_01695 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CADDLEGK_01696 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
CADDLEGK_01697 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CADDLEGK_01698 0.0 XK27_09800 I Acyltransferase
CADDLEGK_01699 9.7e-36 XK27_09805 S MORN repeat protein
CADDLEGK_01700 2.4e-77 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CADDLEGK_01701 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CADDLEGK_01702 4.8e-93 adk 2.7.4.3 F topology modulation protein
CADDLEGK_01704 4.7e-197 ltrA S Low temperature requirement protein
CADDLEGK_01705 5.5e-173 yeiH S membrane
CADDLEGK_01706 8e-88 K sequence-specific DNA binding
CADDLEGK_01707 1.2e-156 L Replication initiation factor
CADDLEGK_01708 1.9e-18 S Domain of unknown function (DUF3173)
CADDLEGK_01709 1.3e-215 int L Belongs to the 'phage' integrase family
CADDLEGK_01711 7e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
CADDLEGK_01712 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CADDLEGK_01713 6.3e-44 yrzL S Belongs to the UPF0297 family
CADDLEGK_01714 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CADDLEGK_01715 3.2e-44 yrzB S Belongs to the UPF0473 family
CADDLEGK_01717 3.5e-220 vncS 2.7.13.3 T Histidine kinase
CADDLEGK_01718 4.4e-115 K Response regulator receiver domain protein
CADDLEGK_01719 3.5e-239 vex3 V Efflux ABC transporter, permease protein
CADDLEGK_01720 1.9e-107 vex2 V abc transporter atp-binding protein
CADDLEGK_01721 3.7e-211 vex1 V Efflux ABC transporter, permease protein
CADDLEGK_01722 1.1e-283 XK27_07020 S Belongs to the UPF0371 family
CADDLEGK_01724 3.8e-196 gldA 1.1.1.6 C glycerol dehydrogenase
CADDLEGK_01725 4.2e-178 XK27_10475 S oxidoreductase
CADDLEGK_01726 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
CADDLEGK_01727 9.9e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
CADDLEGK_01728 9.4e-178 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
CADDLEGK_01729 3.2e-223 thrE K Psort location CytoplasmicMembrane, score
CADDLEGK_01730 0.0 M Putative cell wall binding repeat
CADDLEGK_01731 6.4e-35 S Immunity protein 41
CADDLEGK_01732 0.0 pepO 3.4.24.71 O Peptidase family M13
CADDLEGK_01733 2.4e-08 S Enterocin A Immunity
CADDLEGK_01734 1.7e-190 mccF V LD-carboxypeptidase
CADDLEGK_01735 8.8e-14 S integral membrane protein
CADDLEGK_01736 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
CADDLEGK_01737 2.3e-120 yhfC S Putative membrane peptidase family (DUF2324)
CADDLEGK_01738 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
CADDLEGK_01740 1.6e-240 S dextransucrase activity
CADDLEGK_01741 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
CADDLEGK_01742 0.0 S dextransucrase activity
CADDLEGK_01743 0.0 S dextransucrase activity
CADDLEGK_01744 0.0 S dextransucrase activity
CADDLEGK_01745 3.8e-82 S dextransucrase activity
CADDLEGK_01746 0.0 M Putative cell wall binding repeat
CADDLEGK_01747 1.6e-240 tcdB S dextransucrase activity
CADDLEGK_01748 0.0 S dextransucrase activity
CADDLEGK_01749 2.8e-100 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CADDLEGK_01750 5.2e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CADDLEGK_01751 0.0 M Putative cell wall binding repeat
CADDLEGK_01752 1.4e-286 S dextransucrase activity
CADDLEGK_01753 0.0 S dextransucrase activity
CADDLEGK_01754 0.0 S dextransucrase activity
CADDLEGK_01756 1.3e-134 XK27_00785 S CAAX protease self-immunity
CADDLEGK_01757 1.1e-240 EGP Major facilitator Superfamily
CADDLEGK_01758 6.5e-64 rmaI K Transcriptional regulator, MarR family
CADDLEGK_01759 1.5e-92 maa 2.3.1.79 GK Maltose O-acetyltransferase
CADDLEGK_01760 4e-136 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
CADDLEGK_01761 0.0 3.5.1.28 M domain protein
CADDLEGK_01762 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
CADDLEGK_01763 1.5e-109 K Helix-turn-helix domain, rpiR family
CADDLEGK_01764 3.8e-17 3.2.1.51 GH95 U LPXTG cell wall anchor motif
CADDLEGK_01765 7.9e-34 L COG1943 Transposase and inactivated derivatives
CADDLEGK_01766 2.2e-133 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CADDLEGK_01767 5.6e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CADDLEGK_01768 1e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CADDLEGK_01770 0.0 typA T GTP-binding protein TypA
CADDLEGK_01771 1.2e-177 glk 2.7.1.2 G Glucokinase
CADDLEGK_01772 5.4e-27 yqgQ S protein conserved in bacteria
CADDLEGK_01773 5.2e-83 perR P Belongs to the Fur family
CADDLEGK_01774 9.3e-92 dps P Belongs to the Dps family
CADDLEGK_01775 1.7e-114 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
CADDLEGK_01776 3.6e-172 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
CADDLEGK_01777 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
CADDLEGK_01778 1.3e-185 holA 2.7.7.7 L DNA polymerase III delta subunit
CADDLEGK_01779 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CADDLEGK_01780 1.8e-63 S Domain of unknown function (DUF4430)
CADDLEGK_01781 6.7e-73 S Psort location CytoplasmicMembrane, score
CADDLEGK_01782 6e-129 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
CADDLEGK_01783 2.1e-133 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
CADDLEGK_01784 1.9e-164 sitA P Belongs to the bacterial solute-binding protein 9 family
CADDLEGK_01785 3.6e-117 sirR K iron dependent repressor
CADDLEGK_01786 9.9e-134 htpX O Belongs to the peptidase M48B family
CADDLEGK_01787 7.7e-92 lemA S LemA family
CADDLEGK_01788 5.1e-171 spd F DNA RNA non-specific endonuclease
CADDLEGK_01789 0.0 2.4.1.21 GT5 M Right handed beta helix region
CADDLEGK_01790 1.9e-135 S double-stranded DNA endodeoxyribonuclease activity
CADDLEGK_01791 8.1e-304 hsdM 2.1.1.72 V type I restriction-modification system
CADDLEGK_01792 1.9e-130 S Protein conserved in bacteria
CADDLEGK_01793 1.3e-105
CADDLEGK_01794 1e-141 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
CADDLEGK_01795 3.7e-192
CADDLEGK_01796 0.0 S Domain of unknown function DUF87
CADDLEGK_01797 1.1e-160 S SIR2-like domain
CADDLEGK_01798 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
CADDLEGK_01799 1.1e-44 K Helix-turn-helix domain
CADDLEGK_01800 9.9e-45 S Phage derived protein Gp49-like (DUF891)
CADDLEGK_01801 2.7e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CADDLEGK_01802 8.4e-210 MA20_36090 S Protein of unknown function (DUF2974)
CADDLEGK_01803 2.8e-111 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CADDLEGK_01804 1.6e-157 5.2.1.8 G hydrolase
CADDLEGK_01805 5.3e-27 P Hemerythrin HHE cation binding domain protein
CADDLEGK_01806 2e-142 XK27_00880 3.4.17.14, 3.5.1.28 M Glycosyl hydrolase, family 25
CADDLEGK_01807 8.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CADDLEGK_01808 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
CADDLEGK_01809 1.5e-174 S hydrolase
CADDLEGK_01810 8.4e-23
CADDLEGK_01811 6e-137 M LysM domain
CADDLEGK_01812 8.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CADDLEGK_01813 3.8e-11
CADDLEGK_01814 3.6e-180 dapB 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
CADDLEGK_01815 9.4e-97 K MerR, DNA binding
CADDLEGK_01816 0.0 L helicase
CADDLEGK_01817 2.7e-48 L helicase
CADDLEGK_01818 9.5e-65 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
CADDLEGK_01819 8.1e-11
CADDLEGK_01820 2.4e-232 mntH P H( )-stimulated, divalent metal cation uptake system
CADDLEGK_01821 1.1e-33 XK27_12190 S protein conserved in bacteria
CADDLEGK_01823 1e-85 bioY S biotin synthase
CADDLEGK_01824 7.5e-252 yegQ O Peptidase U32
CADDLEGK_01825 2e-177 yegQ O Peptidase U32
CADDLEGK_01827 4.2e-69 ytxH S General stress protein
CADDLEGK_01828 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CADDLEGK_01829 2.1e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CADDLEGK_01830 2e-166 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CADDLEGK_01831 2.2e-41 pspC KT PspC domain
CADDLEGK_01832 0.0 yhgF K Transcriptional accessory protein
CADDLEGK_01834 4.6e-155 XK27_03015 S permease
CADDLEGK_01835 2.9e-148 ycgQ S TIGR03943 family
CADDLEGK_01836 1.1e-287 sulP P Sulfate permease and related transporters (MFS superfamily)
CADDLEGK_01837 7.3e-104
CADDLEGK_01838 6e-117 estA E GDSL-like Lipase/Acylhydrolase
CADDLEGK_01839 4.1e-45 S CAAX protease self-immunity
CADDLEGK_01840 1.1e-37 S CAAX protease self-immunity
CADDLEGK_01841 3.7e-37
CADDLEGK_01843 5.2e-65 yqeB S Pyrimidine dimer DNA glycosylase
CADDLEGK_01844 2.7e-59 S Protein of unknown function (DUF1722)
CADDLEGK_01845 2.2e-19 S Bacterial lipoprotein
CADDLEGK_01846 6.8e-11
CADDLEGK_01847 5.2e-120 V CAAX protease self-immunity
CADDLEGK_01848 9.3e-47
CADDLEGK_01849 5.2e-59 K TetR family transcriptional regulator
CADDLEGK_01850 7.1e-80 Q Methyltransferase domain
CADDLEGK_01851 1.6e-114 ybbA S Putative esterase
CADDLEGK_01852 2.1e-172 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
CADDLEGK_01853 3.4e-135 fecE 3.6.3.34 HP ABC transporter
CADDLEGK_01854 6.1e-151 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CADDLEGK_01855 1.6e-124 V CAAX protease self-immunity
CADDLEGK_01856 1.6e-157 S Domain of unknown function (DUF4300)
CADDLEGK_01857 1.9e-95 tetR K transcriptional regulator
CADDLEGK_01858 2.4e-285 norB P Major facilitator superfamily
CADDLEGK_01859 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CADDLEGK_01860 3.3e-83 yxjI S LURP-one-related
CADDLEGK_01861 7.8e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
CADDLEGK_01862 1.9e-127 yrrM 2.1.1.104 S O-Methyltransferase
CADDLEGK_01863 2e-217 oxlT P COG0477 Permeases of the major facilitator superfamily
CADDLEGK_01864 0.0 pepF E oligoendopeptidase F
CADDLEGK_01865 1.9e-162 coiA 3.6.4.12 S Competence protein
CADDLEGK_01866 5.2e-78 L transposition
CADDLEGK_01867 1.3e-55 insK L Integrase core domain protein
CADDLEGK_01868 7.3e-163 S CHAP domain
CADDLEGK_01869 2.5e-307 S Glucan-binding protein C
CADDLEGK_01870 2.7e-105 S CAAX amino terminal protease family protein
CADDLEGK_01871 4.7e-168 K transcriptional regulator (lysR family)
CADDLEGK_01872 9.6e-163 S reductase
CADDLEGK_01873 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CADDLEGK_01878 2.8e-191 phoH T phosphate starvation-inducible protein PhoH
CADDLEGK_01879 6e-137 sip M LysM domain protein
CADDLEGK_01880 3.7e-34 yozE S Belongs to the UPF0346 family
CADDLEGK_01881 7.7e-160 cvfB S Protein conserved in bacteria
CADDLEGK_01882 1.7e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CADDLEGK_01883 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CADDLEGK_01884 2.8e-216 sptS 2.7.13.3 T Histidine kinase
CADDLEGK_01885 6.4e-117 T response regulator
CADDLEGK_01886 5.3e-110 2.7.6.5 S Region found in RelA / SpoT proteins
CADDLEGK_01887 1.8e-113 K Acetyltransferase (GNAT) family
CADDLEGK_01888 0.0 lmrA2 V abc transporter atp-binding protein
CADDLEGK_01889 0.0 lmrA1 V abc transporter atp-binding protein
CADDLEGK_01890 3.1e-50 K DNA-binding transcription factor activity
CADDLEGK_01891 5.1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CADDLEGK_01892 4.9e-280 S Psort location CytoplasmicMembrane, score
CADDLEGK_01893 1.5e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
CADDLEGK_01894 5.5e-211 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
CADDLEGK_01895 1.6e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
CADDLEGK_01896 2.9e-26 U response to pH
CADDLEGK_01897 0.0 yfmR S abc transporter atp-binding protein
CADDLEGK_01898 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CADDLEGK_01899 1.3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CADDLEGK_01900 1.4e-150 XK27_08360 S EDD domain protein, DegV family
CADDLEGK_01901 5e-63 WQ51_03320 S cog cog4835
CADDLEGK_01902 1.7e-133 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CADDLEGK_01903 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CADDLEGK_01904 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
CADDLEGK_01905 3.8e-96 2.3.1.128 K acetyltransferase
CADDLEGK_01906 5.2e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CADDLEGK_01907 1.1e-291 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CADDLEGK_01908 6.3e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CADDLEGK_01909 8e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
CADDLEGK_01911 7.6e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CADDLEGK_01912 3.2e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CADDLEGK_01913 0.0 fruA 2.7.1.202 G phosphotransferase system
CADDLEGK_01914 1.1e-164 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CADDLEGK_01915 3.1e-125 fruR K transcriptional
CADDLEGK_01916 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
CADDLEGK_01917 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CADDLEGK_01918 2e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CADDLEGK_01919 5e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CADDLEGK_01920 4.1e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CADDLEGK_01921 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CADDLEGK_01922 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CADDLEGK_01923 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CADDLEGK_01924 1.8e-125 IQ reductase
CADDLEGK_01925 5.2e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
CADDLEGK_01926 3.7e-171 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
CADDLEGK_01927 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CADDLEGK_01928 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CADDLEGK_01929 5.2e-72 marR K Transcriptional regulator, MarR family
CADDLEGK_01930 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
CADDLEGK_01931 1.8e-113 S HAD hydrolase, family IA, variant 3
CADDLEGK_01932 8.2e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
CADDLEGK_01933 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
CADDLEGK_01934 1.5e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CADDLEGK_01935 2e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
CADDLEGK_01936 7.8e-102 ygaC J Belongs to the UPF0374 family
CADDLEGK_01937 1.4e-107 S Domain of unknown function (DUF1803)
CADDLEGK_01938 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)