ORF_ID e_value Gene_name EC_number CAZy COGs Description
BLKGCIPE_00001 2.4e-130 cbiO P ABC transporter
BLKGCIPE_00002 1.1e-137 ET ABC transporter substrate-binding protein
BLKGCIPE_00003 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
BLKGCIPE_00004 4.5e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
BLKGCIPE_00005 7.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BLKGCIPE_00006 1.2e-99 metI P ABC transporter (Permease
BLKGCIPE_00007 4.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BLKGCIPE_00008 2.3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
BLKGCIPE_00009 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
BLKGCIPE_00010 1.1e-138 S HAD hydrolase, family IA, variant
BLKGCIPE_00011 1.3e-159 rrmA 2.1.1.187 Q methyltransferase
BLKGCIPE_00015 2.9e-44 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BLKGCIPE_00016 5e-108
BLKGCIPE_00017 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
BLKGCIPE_00018 1.5e-166 dnaI L Primosomal protein DnaI
BLKGCIPE_00019 1.6e-216 dnaB L Replication initiation and membrane attachment
BLKGCIPE_00020 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BLKGCIPE_00021 2.3e-176 T PhoQ Sensor
BLKGCIPE_00022 2.5e-131 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
BLKGCIPE_00023 2.9e-168 sitA P Belongs to the bacterial solute-binding protein 9 family
BLKGCIPE_00024 1.4e-118 sirR K iron dependent repressor
BLKGCIPE_00025 1.2e-134 htpX O Belongs to the peptidase M48B family
BLKGCIPE_00026 1e-91 lemA S LemA family
BLKGCIPE_00027 4.2e-173 spd F DNA RNA non-specific endonuclease
BLKGCIPE_00028 3.5e-15 2.4.1.21 GT5 M Right handed beta helix region
BLKGCIPE_00030 3e-176 S oxidoreductase
BLKGCIPE_00031 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
BLKGCIPE_00032 8.2e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
BLKGCIPE_00033 0.0 clpE O Belongs to the ClpA ClpB family
BLKGCIPE_00034 3.7e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BLKGCIPE_00035 1e-34 ykuJ S protein conserved in bacteria
BLKGCIPE_00036 2.8e-140 ykuT M mechanosensitive ion channel
BLKGCIPE_00037 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BLKGCIPE_00038 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
BLKGCIPE_00039 6.4e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
BLKGCIPE_00040 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
BLKGCIPE_00041 1.9e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BLKGCIPE_00042 1.9e-203 iscS 2.8.1.7 E Cysteine desulfurase
BLKGCIPE_00043 8.2e-60 XK27_04120 S Putative amino acid metabolism
BLKGCIPE_00044 2.1e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BLKGCIPE_00045 1.8e-127 puuD T peptidase C26
BLKGCIPE_00046 1.8e-114 radC E Belongs to the UPF0758 family
BLKGCIPE_00047 7.5e-166
BLKGCIPE_00048 4.3e-46 M Psort location CytoplasmicMembrane, score
BLKGCIPE_00049 4.3e-156 rfbJ M Glycosyl transferase family 2
BLKGCIPE_00050 0.0 rgpF M Rhamnan synthesis protein F
BLKGCIPE_00051 9.2e-184 rgpEc GT2 M Glycosyl transferase family 2
BLKGCIPE_00052 2e-222 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
BLKGCIPE_00053 5.2e-142 rgpC GM Transport permease protein
BLKGCIPE_00054 1e-173 rgpB GT2 M Glycosyltransferase, group 2 family protein
BLKGCIPE_00055 6.1e-213 rgpA GT4 M Domain of unknown function (DUF1972)
BLKGCIPE_00056 1.9e-158 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
BLKGCIPE_00057 6.1e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
BLKGCIPE_00058 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
BLKGCIPE_00059 1.5e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
BLKGCIPE_00060 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
BLKGCIPE_00061 4.6e-32 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
BLKGCIPE_00062 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
BLKGCIPE_00063 1.9e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
BLKGCIPE_00064 1.1e-211 arcT 2.6.1.1 E Aminotransferase
BLKGCIPE_00065 2.8e-114 S HAD hydrolase, family IA, variant 3
BLKGCIPE_00066 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
BLKGCIPE_00067 5.2e-72 marR K Transcriptional regulator, MarR family
BLKGCIPE_00068 4.6e-169 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLKGCIPE_00069 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLKGCIPE_00070 2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
BLKGCIPE_00071 7.2e-62 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLKGCIPE_00072 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
BLKGCIPE_00073 0.0 smc D Required for chromosome condensation and partitioning
BLKGCIPE_00074 1.7e-91 S Protein of unknown function (DUF3278)
BLKGCIPE_00075 2.9e-82 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
BLKGCIPE_00076 1.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
BLKGCIPE_00077 1.5e-86 ebsA S Family of unknown function (DUF5322)
BLKGCIPE_00078 2.4e-17 M LysM domain
BLKGCIPE_00079 4.7e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
BLKGCIPE_00080 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BLKGCIPE_00081 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
BLKGCIPE_00082 2.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BLKGCIPE_00083 2.5e-52 XK27_03610 K Gnat family
BLKGCIPE_00084 5.8e-297 ccs S the current gene model (or a revised gene model) may contain a frame shift
BLKGCIPE_00085 3.2e-44 yrzB S Belongs to the UPF0473 family
BLKGCIPE_00086 2.3e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BLKGCIPE_00087 6.3e-44 yrzL S Belongs to the UPF0297 family
BLKGCIPE_00088 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
BLKGCIPE_00089 7e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
BLKGCIPE_00091 3.4e-51 int L Belongs to the 'phage' integrase family
BLKGCIPE_00092 1.6e-126 XK27_08875 O Zinc-dependent metalloprotease
BLKGCIPE_00093 2.2e-18 XK27_08880
BLKGCIPE_00094 1e-75 fld C Flavodoxin
BLKGCIPE_00095 7e-281 clcA P Chloride transporter, ClC family
BLKGCIPE_00096 4.5e-29 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
BLKGCIPE_00097 3.8e-213 XK27_05110 P Chloride transporter ClC family
BLKGCIPE_00098 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
BLKGCIPE_00100 5.5e-13 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
BLKGCIPE_00101 2.1e-90 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
BLKGCIPE_00102 4.3e-177 yubA S permease
BLKGCIPE_00103 4.4e-225 G COG0457 FOG TPR repeat
BLKGCIPE_00104 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
BLKGCIPE_00105 2e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
BLKGCIPE_00106 4.8e-174 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
BLKGCIPE_00107 0.0 amiA E ABC transporter, substrate-binding protein, family 5
BLKGCIPE_00108 1.6e-52 bta 1.8.1.8 CO cell redox homeostasis
BLKGCIPE_00109 8.2e-59 L thioesterase
BLKGCIPE_00110 6e-143 S Macro domain protein
BLKGCIPE_00111 2.4e-50 trxA O Belongs to the thioredoxin family
BLKGCIPE_00112 7.2e-74 yccU S CoA-binding protein
BLKGCIPE_00113 6.6e-145 tatD L Hydrolase, tatd
BLKGCIPE_00114 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BLKGCIPE_00115 3.8e-154 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
BLKGCIPE_00118 1.1e-178 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
BLKGCIPE_00119 1.1e-259 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
BLKGCIPE_00120 7.4e-116 yebC M Membrane
BLKGCIPE_00121 1.8e-165 yocS S Transporter
BLKGCIPE_00122 2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
BLKGCIPE_00123 1.3e-274 V ABC transporter transmembrane region
BLKGCIPE_00125 6.7e-75 XK27_01300 P Protein conserved in bacteria
BLKGCIPE_00126 1.1e-84 FNV0100 F Belongs to the Nudix hydrolase family
BLKGCIPE_00127 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BLKGCIPE_00128 4.9e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
BLKGCIPE_00129 2.7e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
BLKGCIPE_00130 1.8e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
BLKGCIPE_00131 1.9e-132 ais G Phosphoglycerate mutase
BLKGCIPE_00132 8.2e-238 XK27_08635 S UPF0210 protein
BLKGCIPE_00133 2.4e-84 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
BLKGCIPE_00134 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BLKGCIPE_00135 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
BLKGCIPE_00136 3.4e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
BLKGCIPE_00137 2.2e-194 yhjX P Major Facilitator
BLKGCIPE_00138 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BLKGCIPE_00139 2.6e-36 cylB V ABC-2 type transporter
BLKGCIPE_00140 9e-75 K COG3279 Response regulator of the LytR AlgR family
BLKGCIPE_00141 7.6e-31 S Protein of unknown function (DUF3021)
BLKGCIPE_00142 1.1e-116 mta K Transcriptional
BLKGCIPE_00143 3.3e-121 yhcA V abc transporter atp-binding protein
BLKGCIPE_00144 1.6e-217 macB_2 V FtsX-like permease family
BLKGCIPE_00145 1.1e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BLKGCIPE_00146 9e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
BLKGCIPE_00147 1.7e-73 yhaI S Protein of unknown function (DUF805)
BLKGCIPE_00148 1.7e-254 pepC 3.4.22.40 E aminopeptidase
BLKGCIPE_00149 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BLKGCIPE_00150 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
BLKGCIPE_00151 5.8e-94 ypsA S Belongs to the UPF0398 family
BLKGCIPE_00152 9.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
BLKGCIPE_00153 8.7e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
BLKGCIPE_00154 2.8e-277 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
BLKGCIPE_00155 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
BLKGCIPE_00156 7.4e-23
BLKGCIPE_00157 4.7e-257 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
BLKGCIPE_00158 3.6e-105 S CAAX amino terminal protease family protein
BLKGCIPE_00159 4.7e-168 K transcriptional regulator (lysR family)
BLKGCIPE_00160 6.2e-162 S reductase
BLKGCIPE_00161 1.2e-82 S Putative small multi-drug export protein
BLKGCIPE_00162 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BLKGCIPE_00163 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
BLKGCIPE_00164 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
BLKGCIPE_00165 1e-287 ahpF O alkyl hydroperoxide reductase
BLKGCIPE_00167 4.1e-238 nylA 3.5.1.4 J Belongs to the amidase family
BLKGCIPE_00168 5.1e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
BLKGCIPE_00169 2.4e-81 yecS P ABC transporter (Permease
BLKGCIPE_00171 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
BLKGCIPE_00172 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
BLKGCIPE_00173 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
BLKGCIPE_00174 9.5e-169 murB 1.3.1.98 M cell wall formation
BLKGCIPE_00175 2.9e-81 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BLKGCIPE_00176 1.1e-81 ypmB S Protein conserved in bacteria
BLKGCIPE_00177 5.4e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
BLKGCIPE_00178 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
BLKGCIPE_00179 8.2e-19
BLKGCIPE_00180 9.6e-201 pmrB EGP Major facilitator Superfamily
BLKGCIPE_00181 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
BLKGCIPE_00182 1.3e-122 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BLKGCIPE_00183 9.7e-82 queD 4.1.2.50, 4.2.3.12 H synthase
BLKGCIPE_00184 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
BLKGCIPE_00185 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
BLKGCIPE_00186 2.2e-202 D nuclear chromosome segregation
BLKGCIPE_00187 1.2e-135 yejC S cyclic nucleotide-binding protein
BLKGCIPE_00188 7e-164 rapZ S Displays ATPase and GTPase activities
BLKGCIPE_00189 4.3e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
BLKGCIPE_00190 5.7e-161 whiA K May be required for sporulation
BLKGCIPE_00191 1.1e-275 pepD E Dipeptidase
BLKGCIPE_00192 2.1e-146 XK27_10720 D peptidase activity
BLKGCIPE_00193 5.6e-294 adcA P Belongs to the bacterial solute-binding protein 9 family
BLKGCIPE_00194 2.6e-09
BLKGCIPE_00196 1.2e-167 yeiH S Membrane
BLKGCIPE_00197 2.7e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
BLKGCIPE_00198 1.1e-68 nrnA 3.1.13.3, 3.1.3.7 S domain protein
BLKGCIPE_00199 3.4e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
BLKGCIPE_00200 4.4e-45 rpmE2 J 50S ribosomal protein L31
BLKGCIPE_00201 2.7e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
BLKGCIPE_00202 7.6e-164 ypuA S secreted protein
BLKGCIPE_00203 3.5e-70 yaeR E COG0346 Lactoylglutathione lyase and related lyases
BLKGCIPE_00204 6.3e-45 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
BLKGCIPE_00205 8.3e-15 XK27_06920 S membrane
BLKGCIPE_00206 3.6e-109 S Putative adhesin
BLKGCIPE_00207 5.6e-160 XK27_06930 V domain protein
BLKGCIPE_00208 9.9e-97 XK27_06935 K transcriptional regulator
BLKGCIPE_00209 4.1e-54 ypaA M Membrane
BLKGCIPE_00210 1.9e-10
BLKGCIPE_00211 1e-296 V abc transporter atp-binding protein
BLKGCIPE_00212 0.0 V abc transporter atp-binding protein
BLKGCIPE_00213 4.9e-185 XK27_10075 S abc transporter atp-binding protein
BLKGCIPE_00214 2.1e-247 pbuO S permease
BLKGCIPE_00215 4.7e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
BLKGCIPE_00216 7.1e-92 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
BLKGCIPE_00217 2.8e-211 brpA K Transcriptional
BLKGCIPE_00218 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
BLKGCIPE_00219 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BLKGCIPE_00220 1.7e-61 yqhY S protein conserved in bacteria
BLKGCIPE_00221 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLKGCIPE_00222 3.7e-179 scrR K Transcriptional regulator
BLKGCIPE_00223 1.3e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
BLKGCIPE_00224 2.1e-184 D nuclear chromosome segregation
BLKGCIPE_00225 2.2e-123 glnQ E abc transporter atp-binding protein
BLKGCIPE_00226 2.1e-272 glnP P ABC transporter
BLKGCIPE_00227 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
BLKGCIPE_00228 8.3e-18 S Protein of unknown function (DUF3021)
BLKGCIPE_00229 2.7e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
BLKGCIPE_00230 1e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
BLKGCIPE_00231 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
BLKGCIPE_00232 2.4e-234 sufD O assembly protein SufD
BLKGCIPE_00233 1.7e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BLKGCIPE_00234 2.3e-72 nifU C SUF system FeS assembly protein, NifU family
BLKGCIPE_00235 1e-273 sufB O assembly protein SufB
BLKGCIPE_00236 2.3e-311 oppA E ABC transporter substrate-binding protein
BLKGCIPE_00237 9.7e-161 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLKGCIPE_00238 1.9e-165 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLKGCIPE_00239 4.6e-157 oppD P Belongs to the ABC transporter superfamily
BLKGCIPE_00240 7.6e-169 oppF P Belongs to the ABC transporter superfamily
BLKGCIPE_00241 8.5e-122 sdaAB 4.3.1.17 E L-serine dehydratase
BLKGCIPE_00242 3.4e-147 sdaAA 4.3.1.17 E L-serine dehydratase
BLKGCIPE_00243 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
BLKGCIPE_00244 2.4e-45 ftsL D cell division protein FtsL
BLKGCIPE_00245 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
BLKGCIPE_00246 3.7e-25
BLKGCIPE_00249 8.5e-69 yhaI J Protein of unknown function (DUF805)
BLKGCIPE_00250 3.6e-64 yhaI S Protein of unknown function (DUF805)
BLKGCIPE_00251 1.7e-218 pcrA 3.6.4.12 L ATP-dependent DNA helicase
BLKGCIPE_00252 8.6e-240 metY 2.5.1.49 E o-acetylhomoserine
BLKGCIPE_00253 1.3e-93 S haloacid dehalogenase-like hydrolase
BLKGCIPE_00254 1.2e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BLKGCIPE_00255 6.2e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
BLKGCIPE_00256 2.8e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
BLKGCIPE_00257 1.7e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BLKGCIPE_00258 5.4e-145 ycdO P periplasmic lipoprotein involved in iron transport
BLKGCIPE_00259 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BLKGCIPE_00260 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLKGCIPE_00261 1.8e-96 3.1.3.18 S IA, variant 1
BLKGCIPE_00262 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
BLKGCIPE_00263 3.5e-56 lrgA S Effector of murein hydrolase LrgA
BLKGCIPE_00264 2.3e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BLKGCIPE_00265 6.2e-91 yceD K metal-binding, possibly nucleic acid-binding protein
BLKGCIPE_00266 2.6e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
BLKGCIPE_00267 1.9e-237 P COG0168 Trk-type K transport systems, membrane components
BLKGCIPE_00268 4.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
BLKGCIPE_00269 3e-306 ybiT S ABC transporter
BLKGCIPE_00270 2e-194 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
BLKGCIPE_00272 2.1e-50
BLKGCIPE_00273 2.3e-94 S CAAX protease self-immunity
BLKGCIPE_00274 7.1e-118 estA E GDSL-like Lipase/Acylhydrolase
BLKGCIPE_00275 7.3e-104
BLKGCIPE_00276 1.9e-10 S dextransucrase activity
BLKGCIPE_00277 5.6e-34 rarD S Transporter
BLKGCIPE_00278 3.4e-16 T peptidase
BLKGCIPE_00279 3e-14 coiA 3.6.4.12 S Competence protein
BLKGCIPE_00280 7.1e-109 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BLKGCIPE_00281 1.1e-106 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
BLKGCIPE_00282 5.7e-172 S Helix-hairpin-helix DNA-binding motif class 1
BLKGCIPE_00283 3.9e-151 ftsI 3.4.16.4 M penicillin-binding protein
BLKGCIPE_00284 1.4e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLKGCIPE_00285 3.7e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
BLKGCIPE_00287 1.7e-84 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BLKGCIPE_00288 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BLKGCIPE_00289 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BLKGCIPE_00290 1e-68 S cog cog4699
BLKGCIPE_00291 2.1e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BLKGCIPE_00292 3.7e-143 cglB U protein transport across the cell outer membrane
BLKGCIPE_00293 2.2e-43 comGC U Required for transformation and DNA binding
BLKGCIPE_00294 8.4e-70 cglD NU Competence protein
BLKGCIPE_00295 3.1e-15 NU Type II secretory pathway pseudopilin
BLKGCIPE_00296 2e-71 comGF U Competence protein ComGF
BLKGCIPE_00297 2e-12 comGF U Putative Competence protein ComGF
BLKGCIPE_00298 2.5e-175 ytxK 2.1.1.72 L DNA methylase
BLKGCIPE_00299 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BLKGCIPE_00300 1.5e-26 lanR K sequence-specific DNA binding
BLKGCIPE_00301 2.1e-109 V CAAX protease self-immunity
BLKGCIPE_00303 3e-103 S CAAX amino terminal protease family protein
BLKGCIPE_00304 3.7e-129 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLKGCIPE_00305 2e-202 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
BLKGCIPE_00306 2e-08 XK27_10305 S Domain of unknown function (DUF4651)
BLKGCIPE_00307 1.1e-153 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
BLKGCIPE_00308 1.4e-43 veg S Biofilm formation stimulator VEG
BLKGCIPE_00309 5.1e-131 tauC P ABC transporter (Permease
BLKGCIPE_00310 2.9e-190 tauA P ABC transporter, substratebinding protein
BLKGCIPE_00311 8.4e-131 tauB P abc transporter atp-binding protein
BLKGCIPE_00312 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BLKGCIPE_00313 2.1e-117 ywaF S Integral membrane protein (intg_mem_TP0381)
BLKGCIPE_00314 5.7e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
BLKGCIPE_00315 4.3e-197 S dextransucrase activity
BLKGCIPE_00316 1.3e-114 L Transposase
BLKGCIPE_00317 6.5e-74 L Transposase
BLKGCIPE_00318 1.5e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
BLKGCIPE_00319 2.4e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
BLKGCIPE_00320 2.1e-76 yueI S Protein of unknown function (DUF1694)
BLKGCIPE_00321 2.4e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
BLKGCIPE_00322 7.2e-200 yyaQ S YjbR
BLKGCIPE_00323 3.2e-181 ccpA K Catabolite control protein A
BLKGCIPE_00324 1.7e-196 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
BLKGCIPE_00325 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
BLKGCIPE_00326 5.7e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BLKGCIPE_00327 1.9e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
BLKGCIPE_00328 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
BLKGCIPE_00329 2e-33 secG U Preprotein translocase subunit SecG
BLKGCIPE_00330 2.2e-221 mdtG EGP Major facilitator Superfamily
BLKGCIPE_00331 1.3e-102 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BLKGCIPE_00332 1.3e-148 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
BLKGCIPE_00333 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BLKGCIPE_00334 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
BLKGCIPE_00335 3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BLKGCIPE_00336 1.6e-149 licT K antiterminator
BLKGCIPE_00337 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BLKGCIPE_00338 6.1e-146 pbp2b 3.4.16.4 M penicillin-binding protein
BLKGCIPE_00339 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BLKGCIPE_00340 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BLKGCIPE_00341 8e-42 ylxQ J ribosomal protein
BLKGCIPE_00342 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
BLKGCIPE_00344 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLKGCIPE_00346 1.3e-37
BLKGCIPE_00347 8.7e-201 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BLKGCIPE_00348 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BLKGCIPE_00349 3.2e-124 ftsE D cell division ATP-binding protein FtsE
BLKGCIPE_00350 5e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BLKGCIPE_00351 9.6e-94 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BLKGCIPE_00352 9.7e-22
BLKGCIPE_00353 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BLKGCIPE_00354 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
BLKGCIPE_00355 6.5e-182 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
BLKGCIPE_00356 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BLKGCIPE_00357 1.3e-121 L overlaps another CDS with the same product name
BLKGCIPE_00358 8.5e-47 L Helix-turn-helix domain
BLKGCIPE_00359 4.6e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
BLKGCIPE_00360 0.0 yjcE P NhaP-type Na H and K H antiporters
BLKGCIPE_00362 1e-96 ytqB 2.1.1.176 J (SAM)-dependent
BLKGCIPE_00363 5.4e-183 yhcC S radical SAM protein
BLKGCIPE_00364 3.5e-186 ylbL T Belongs to the peptidase S16 family
BLKGCIPE_00365 1.1e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BLKGCIPE_00366 1.9e-92 rsmD 2.1.1.171 L Methyltransferase
BLKGCIPE_00367 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
BLKGCIPE_00368 5e-10 S Protein of unknown function (DUF4059)
BLKGCIPE_00369 1.6e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
BLKGCIPE_00370 6.1e-163 yxeN P ABC transporter (Permease
BLKGCIPE_00371 3.3e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
BLKGCIPE_00372 3.6e-35
BLKGCIPE_00373 1.2e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLKGCIPE_00374 0.0 pflB 2.3.1.54 C formate acetyltransferase'
BLKGCIPE_00376 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
BLKGCIPE_00378 6.2e-120 yoaK S Protein of unknown function (DUF1275)
BLKGCIPE_00379 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BLKGCIPE_00380 2.4e-202 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
BLKGCIPE_00381 1.1e-133 parB K Belongs to the ParB family
BLKGCIPE_00382 1.2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BLKGCIPE_00383 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
BLKGCIPE_00384 1.1e-29 yyzM S Protein conserved in bacteria
BLKGCIPE_00385 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
BLKGCIPE_00386 2e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
BLKGCIPE_00387 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BLKGCIPE_00388 6.3e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
BLKGCIPE_00389 3e-60 divIC D Septum formation initiator
BLKGCIPE_00391 4.5e-236 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
BLKGCIPE_00392 1.1e-236 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
BLKGCIPE_00393 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
BLKGCIPE_00394 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BLKGCIPE_00395 1e-145 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
BLKGCIPE_00396 1.6e-188 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
BLKGCIPE_00397 3.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
BLKGCIPE_00398 1.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BLKGCIPE_00399 2.3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
BLKGCIPE_00400 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLKGCIPE_00401 2.6e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
BLKGCIPE_00405 9.2e-110 mreC M Involved in formation and maintenance of cell shape
BLKGCIPE_00406 4.2e-84 mreD M rod shape-determining protein MreD
BLKGCIPE_00407 1.1e-89 usp 3.5.1.28 CBM50 S CHAP domain
BLKGCIPE_00408 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BLKGCIPE_00409 2.1e-76 S Domain of unknown function (DUF1803)
BLKGCIPE_00410 7.8e-102 ygaC J Belongs to the UPF0374 family
BLKGCIPE_00411 1.7e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
BLKGCIPE_00412 3.4e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLKGCIPE_00413 1.8e-171 1.8.5.7 O Glutathione S-transferase, C-terminal domain
BLKGCIPE_00414 2.5e-151 1.8.5.7 O Glutathione S-transferase
BLKGCIPE_00416 8.7e-60 K Acetyltransferase (GNAT) domain
BLKGCIPE_00417 1.4e-97 ET Bacterial extracellular solute-binding proteins, family 3
BLKGCIPE_00419 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
BLKGCIPE_00420 6.1e-180 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BLKGCIPE_00421 2.1e-191 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BLKGCIPE_00422 3.3e-40 XK27_08085
BLKGCIPE_00423 5.2e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLKGCIPE_00424 3.1e-59 5.2.1.8 G hydrolase
BLKGCIPE_00425 1.6e-69 5.2.1.8 G hydrolase
BLKGCIPE_00426 5.3e-27 P Hemerythrin HHE cation binding domain protein
BLKGCIPE_00427 1e-141 XK27_00880 3.4.17.14, 3.5.1.28 M Glycosyl hydrolase, family 25
BLKGCIPE_00428 1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BLKGCIPE_00429 1.4e-150 S von Willebrand factor (vWF) type A domain
BLKGCIPE_00430 1.8e-181 yclQ P ABC-type enterochelin transport system, periplasmic component
BLKGCIPE_00431 3.5e-214 dinF V Mate efflux family protein
BLKGCIPE_00432 3.9e-159 holB 2.7.7.7 L dna polymerase iii
BLKGCIPE_00433 1.9e-107 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BLKGCIPE_00435 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BLKGCIPE_00436 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
BLKGCIPE_00437 2e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
BLKGCIPE_00438 3.3e-73 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
BLKGCIPE_00439 6.9e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BLKGCIPE_00440 3.1e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
BLKGCIPE_00441 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
BLKGCIPE_00442 1.2e-50 S Protein of unknown function (DUF3397)
BLKGCIPE_00443 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BLKGCIPE_00444 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
BLKGCIPE_00445 0.0 amiA E ABC transporter, substrate-binding protein, family 5
BLKGCIPE_00446 1.8e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BLKGCIPE_00447 6.7e-232 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
BLKGCIPE_00448 3.7e-157 hpk9 2.7.13.3 T protein histidine kinase activity
BLKGCIPE_00449 7.1e-210 hpk9 2.7.13.3 T protein histidine kinase activity
BLKGCIPE_00450 4.5e-244 fasC 2.7.13.3 T protein histidine kinase activity
BLKGCIPE_00451 2.8e-134 fasA KT Response regulator of the LytR AlgR family
BLKGCIPE_00452 6.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
BLKGCIPE_00453 3.7e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
BLKGCIPE_00454 3.9e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
BLKGCIPE_00455 3.5e-135 fnt P Formate nitrite transporter
BLKGCIPE_00456 3e-82 XK27_09615 C reductase
BLKGCIPE_00457 4.1e-29 pspC KT PspC domain protein
BLKGCIPE_00458 5.2e-119 yqfA K protein, Hemolysin III
BLKGCIPE_00459 3e-78 K hmm pf08876
BLKGCIPE_00460 4.7e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
BLKGCIPE_00461 7.9e-216 mvaS 2.3.3.10 I synthase
BLKGCIPE_00463 1.3e-121 XK27_00785 S CAAX protease self-immunity
BLKGCIPE_00464 1.2e-195 EGP Major facilitator Superfamily
BLKGCIPE_00465 3e-24 EGP Major facilitator Superfamily
BLKGCIPE_00466 1.9e-47 rmaI K Transcriptional regulator, MarR family
BLKGCIPE_00467 6.5e-62 S Psort location Cytoplasmic, score
BLKGCIPE_00468 9.9e-40 vapD S Virulence-associated protein D
BLKGCIPE_00469 5.8e-16
BLKGCIPE_00470 0.0 scrA 2.7.1.211 G pts system
BLKGCIPE_00471 2.6e-174 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
BLKGCIPE_00472 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BLKGCIPE_00473 3.5e-158 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
BLKGCIPE_00474 3.7e-196 S Protein of unknown function (DUF3114)
BLKGCIPE_00475 0.0 mdlB V abc transporter atp-binding protein
BLKGCIPE_00476 0.0 mdlA V abc transporter atp-binding protein
BLKGCIPE_00478 1.7e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLKGCIPE_00479 8e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
BLKGCIPE_00481 8.2e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BLKGCIPE_00482 3.9e-259 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLKGCIPE_00483 0.0 fruA 2.7.1.202 G phosphotransferase system
BLKGCIPE_00484 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
BLKGCIPE_00485 3.1e-125 fruR K transcriptional
BLKGCIPE_00486 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
BLKGCIPE_00487 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
BLKGCIPE_00488 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
BLKGCIPE_00489 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BLKGCIPE_00490 4.1e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
BLKGCIPE_00491 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
BLKGCIPE_00492 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
BLKGCIPE_00493 9.2e-135 adcC P ABC transporter, ATP-binding protein
BLKGCIPE_00494 2.6e-71 adcR K transcriptional
BLKGCIPE_00495 1.1e-181 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BLKGCIPE_00496 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BLKGCIPE_00497 3.6e-26
BLKGCIPE_00498 1.9e-186 lplA 6.3.1.20 H Lipoate-protein ligase
BLKGCIPE_00499 1.8e-39
BLKGCIPE_00500 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
BLKGCIPE_00501 2.7e-301 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
BLKGCIPE_00502 7.8e-180 malR K Transcriptional regulator
BLKGCIPE_00503 5.6e-228 malX G ABC transporter
BLKGCIPE_00504 7.4e-250 malF P ABC transporter (Permease
BLKGCIPE_00505 9.8e-152 malG P ABC transporter (Permease
BLKGCIPE_00506 2.3e-212 msmX P Belongs to the ABC transporter superfamily
BLKGCIPE_00507 1e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
BLKGCIPE_00508 1.6e-118 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BLKGCIPE_00509 1.6e-286 ywbL P COG0672 High-affinity Fe2 Pb2 permease
BLKGCIPE_00510 1.1e-172 ycdB P peroxidase
BLKGCIPE_00513 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLKGCIPE_00514 4.5e-239 agcS E (Alanine) symporter
BLKGCIPE_00515 1e-125 gntR1 K transcriptional
BLKGCIPE_00516 4.9e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BLKGCIPE_00517 2.9e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BLKGCIPE_00518 2.7e-86
BLKGCIPE_00519 2.7e-91 niaR S small molecule binding protein (contains 3H domain)
BLKGCIPE_00520 4e-127 K DNA-binding helix-turn-helix protein
BLKGCIPE_00521 6.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BLKGCIPE_00522 1.8e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLKGCIPE_00523 1.1e-164 GK ROK family
BLKGCIPE_00524 2.4e-158 dprA LU DNA protecting protein DprA
BLKGCIPE_00525 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLKGCIPE_00526 4.6e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
BLKGCIPE_00527 1.3e-51 V ABC-2 family transporter protein
BLKGCIPE_00529 2e-149 S TraX protein
BLKGCIPE_00530 1.5e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BLKGCIPE_00531 2e-11
BLKGCIPE_00533 5.5e-151 V Abi-like protein
BLKGCIPE_00534 5.1e-46 L Single-strand binding protein family
BLKGCIPE_00535 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
BLKGCIPE_00537 1e-20 L the current gene model (or a revised gene model) may contain a frame shift
BLKGCIPE_00538 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
BLKGCIPE_00539 5.8e-137 yfeJ 6.3.5.2 F glutamine amidotransferase
BLKGCIPE_00540 2.3e-181 clcA_2 P Chloride transporter, ClC family
BLKGCIPE_00541 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BLKGCIPE_00542 3.6e-94 S Protein of unknown function (DUF1697)
BLKGCIPE_00543 8e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
BLKGCIPE_00544 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BLKGCIPE_00546 1.8e-50 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
BLKGCIPE_00547 4.1e-225 XK27_05470 E Methionine synthase
BLKGCIPE_00548 8.2e-38 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BLKGCIPE_00549 2.1e-85 mmuP E amino acid
BLKGCIPE_00550 2.8e-171 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
BLKGCIPE_00551 2.2e-30 S Domain of unknown function (DUF1912)
BLKGCIPE_00552 1.1e-12 L Helix-hairpin-helix DNA-binding motif class 1
BLKGCIPE_00553 8.7e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
BLKGCIPE_00554 1.5e-76 corA P CorA-like protein
BLKGCIPE_00555 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
BLKGCIPE_00556 6.6e-41 yazA L endonuclease containing a URI domain
BLKGCIPE_00557 7.9e-140 yabB 2.1.1.223 L Methyltransferase
BLKGCIPE_00558 2.5e-64 nodB3 G deacetylase
BLKGCIPE_00559 1.9e-283 XK27_07020 S Belongs to the UPF0371 family
BLKGCIPE_00561 4.6e-194 gldA 1.1.1.6 C glycerol dehydrogenase
BLKGCIPE_00562 7.2e-178 XK27_10475 S oxidoreductase
BLKGCIPE_00563 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
BLKGCIPE_00564 2.9e-94 dhaL 2.7.1.121 S Dihydroxyacetone kinase
BLKGCIPE_00565 8e-177 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
BLKGCIPE_00566 9.4e-223 thrE K Psort location CytoplasmicMembrane, score
BLKGCIPE_00567 0.0 M Putative cell wall binding repeat
BLKGCIPE_00568 3.5e-133 T Ser Thr phosphatase family protein
BLKGCIPE_00569 1.2e-33 S Immunity protein 41
BLKGCIPE_00570 0.0 pepO 3.4.24.71 O Peptidase family M13
BLKGCIPE_00571 1.9e-217 araT 2.6.1.1 E Aminotransferase
BLKGCIPE_00572 6.1e-140 recO L Involved in DNA repair and RecF pathway recombination
BLKGCIPE_00573 6.2e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
BLKGCIPE_00574 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLKGCIPE_00575 3.8e-243 dcuS 2.7.13.3 T protein histidine kinase activity
BLKGCIPE_00576 1e-246 2.7.13.3 T protein histidine kinase activity
BLKGCIPE_00577 2.7e-91 yacP S RNA-binding protein containing a PIN domain
BLKGCIPE_00578 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLKGCIPE_00580 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BLKGCIPE_00581 8.1e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
BLKGCIPE_00583 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
BLKGCIPE_00584 1e-139 S SseB protein N-terminal domain
BLKGCIPE_00585 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
BLKGCIPE_00586 2.1e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BLKGCIPE_00587 3.5e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BLKGCIPE_00588 0.0 clpC O Belongs to the ClpA ClpB family
BLKGCIPE_00589 1.8e-75 ctsR K Belongs to the CtsR family
BLKGCIPE_00590 3.4e-155 cat 2.3.1.28 S acetyltransferase'
BLKGCIPE_00591 0.0 M family 8
BLKGCIPE_00592 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BLKGCIPE_00594 7.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BLKGCIPE_00595 5.7e-10 O ADP-ribosylglycohydrolase
BLKGCIPE_00596 1e-57 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BLKGCIPE_00597 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BLKGCIPE_00598 4.4e-62 rplQ J ribosomal protein l17
BLKGCIPE_00599 4.6e-241 6.3.2.2 H gamma-glutamylcysteine synthetase
BLKGCIPE_00601 9.2e-192 S hmm pf08843
BLKGCIPE_00602 5.2e-113 K Psort location Cytoplasmic, score
BLKGCIPE_00603 1.7e-59
BLKGCIPE_00604 2e-173 L Belongs to the 'phage' integrase family
BLKGCIPE_00605 3.4e-135 fecE 3.6.3.34 HP ABC transporter
BLKGCIPE_00606 9.4e-160 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLKGCIPE_00607 1.6e-124 V CAAX protease self-immunity
BLKGCIPE_00608 4.9e-53 S Domain of unknown function (DUF4300)
BLKGCIPE_00609 1.8e-243 norM V Multidrug efflux pump
BLKGCIPE_00610 2.6e-152 K sequence-specific DNA binding
BLKGCIPE_00611 3.6e-272 V (ABC) transporter
BLKGCIPE_00612 2.5e-223 pbuX F xanthine permease
BLKGCIPE_00613 2.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
BLKGCIPE_00614 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BLKGCIPE_00615 1.5e-151 T Histidine kinase
BLKGCIPE_00616 1.2e-132 macB2 V ABC transporter, ATP-binding protein
BLKGCIPE_00617 0.0 V ABC transporter (permease)
BLKGCIPE_00618 6.1e-93 XK27_05000 S metal cluster binding
BLKGCIPE_00619 7.6e-30 liaI KT membrane
BLKGCIPE_00620 8.3e-16 liaI KT membrane
BLKGCIPE_00621 1.1e-156 XK27_09825 V abc transporter atp-binding protein
BLKGCIPE_00622 3.4e-132 yvfS V Transporter
BLKGCIPE_00623 7.9e-25 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
BLKGCIPE_00624 2.7e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BLKGCIPE_00625 6.6e-173 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
BLKGCIPE_00626 2.2e-140 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BLKGCIPE_00627 2e-80 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BLKGCIPE_00628 4.2e-23 rpmD J ribosomal protein l30
BLKGCIPE_00629 6.7e-59 rplO J binds to the 23S rRNA
BLKGCIPE_00630 9.5e-210 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
BLKGCIPE_00631 6.6e-116 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
BLKGCIPE_00632 3.5e-120 yujD V lipoprotein transporter activity
BLKGCIPE_00633 0.0 S bacteriocin-associated integral membrane protein
BLKGCIPE_00634 5.5e-19 S Bacteriocin (Lactococcin_972)
BLKGCIPE_00635 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BLKGCIPE_00636 1.7e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BLKGCIPE_00637 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BLKGCIPE_00639 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
BLKGCIPE_00640 3.2e-239 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
BLKGCIPE_00642 2.6e-86 S ECF-type riboflavin transporter, S component
BLKGCIPE_00643 1.3e-154 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
BLKGCIPE_00644 1.2e-81 XK27_01265 S ECF-type riboflavin transporter, S component
BLKGCIPE_00645 1.1e-294 yfmM S abc transporter atp-binding protein
BLKGCIPE_00646 1.4e-256 noxE P NADH oxidase
BLKGCIPE_00647 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
BLKGCIPE_00648 9.9e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
BLKGCIPE_00649 5.9e-216 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
BLKGCIPE_00650 7.9e-103 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BLKGCIPE_00651 1.6e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
BLKGCIPE_00652 5.5e-144 cdsA 2.7.7.41 S Belongs to the CDS family
BLKGCIPE_00653 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BLKGCIPE_00654 5.9e-47 yajC U protein transport
BLKGCIPE_00655 6.1e-126 yeeN K transcriptional regulatory protein
BLKGCIPE_00656 6.5e-282 V ABC transporter
BLKGCIPE_00657 2.5e-150 Z012_04635 K sequence-specific DNA binding
BLKGCIPE_00658 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
BLKGCIPE_00659 1.4e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
BLKGCIPE_00660 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
BLKGCIPE_00661 3.4e-161 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
BLKGCIPE_00662 1.9e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BLKGCIPE_00663 1.2e-88 norM V Multidrug efflux pump
BLKGCIPE_00665 2e-180 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLKGCIPE_00666 5.8e-231 brnQ E Component of the transport system for branched-chain amino acids
BLKGCIPE_00667 1.6e-179 manA 5.3.1.8 G mannose-6-phosphate isomerase
BLKGCIPE_00668 2e-58 S Protein of unknown function (DUF3290)
BLKGCIPE_00669 1.4e-105 S Protein of unknown function (DUF421)
BLKGCIPE_00670 2.5e-13 csbD K CsbD-like
BLKGCIPE_00671 7e-106 S Carbohydrate-binding domain-containing protein Cthe_2159
BLKGCIPE_00672 2e-50 XK27_01300 P Protein conserved in bacteria
BLKGCIPE_00673 5.1e-214 yfnA E amino acid
BLKGCIPE_00675 1.6e-41 C Pyridoxamine 5'-phosphate oxidase
BLKGCIPE_00676 6.9e-97 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
BLKGCIPE_00677 2.7e-79 S Macro domain
BLKGCIPE_00678 3.3e-69 mgrA K Transcriptional regulator, MarR family
BLKGCIPE_00679 3e-156 yvgN C reductase
BLKGCIPE_00680 1.9e-30 XK27_10490
BLKGCIPE_00681 5.3e-40 DJ nuclease activity
BLKGCIPE_00682 1.1e-103 yoaK S Protein of unknown function (DUF1275)
BLKGCIPE_00683 1.9e-107 drgA C nitroreductase
BLKGCIPE_00684 2.7e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
BLKGCIPE_00685 4.4e-64 2.7.13.3 T Histidine kinase
BLKGCIPE_00686 1.1e-73 K Transcriptional regulatory protein, C terminal
BLKGCIPE_00688 2.4e-14
BLKGCIPE_00689 5e-88 V abc transporter atp-binding protein
BLKGCIPE_00690 0.0 3.5.1.28 M domain protein
BLKGCIPE_00691 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
BLKGCIPE_00692 0.0 yfmR S abc transporter atp-binding protein
BLKGCIPE_00693 3.9e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BLKGCIPE_00694 6.7e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BLKGCIPE_00695 1.8e-61 yutD J protein conserved in bacteria
BLKGCIPE_00696 1e-176 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
BLKGCIPE_00698 3.6e-152 EG Permeases of the drug metabolite transporter (DMT) superfamily
BLKGCIPE_00699 3.2e-07 N PFAM Uncharacterised protein family UPF0150
BLKGCIPE_00700 3.5e-112 serB 3.1.3.3 E phosphoserine phosphatase
BLKGCIPE_00701 8.1e-123 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BLKGCIPE_00702 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BLKGCIPE_00703 2.3e-150 cobQ S glutamine amidotransferase
BLKGCIPE_00704 3.1e-14 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
BLKGCIPE_00705 7.6e-289 yfiB1 V abc transporter atp-binding protein
BLKGCIPE_00706 0.0 XK27_10035 V abc transporter atp-binding protein
BLKGCIPE_00707 1.3e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BLKGCIPE_00708 6.6e-237 dltB M Membrane protein involved in D-alanine export
BLKGCIPE_00709 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BLKGCIPE_00710 6.7e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BLKGCIPE_00711 0.0 3.6.3.8 P cation transport ATPase
BLKGCIPE_00712 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
BLKGCIPE_00714 3.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
BLKGCIPE_00715 2e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
BLKGCIPE_00716 1.6e-192 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
BLKGCIPE_00717 2e-203 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
BLKGCIPE_00718 6.1e-94 cvpA S toxin biosynthetic process
BLKGCIPE_00719 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BLKGCIPE_00720 5.9e-155 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLKGCIPE_00721 2.7e-47 K Helix-turn-helix
BLKGCIPE_00722 4.5e-311 sfcA 1.1.1.38, 4.1.1.101 C malic enzyme
BLKGCIPE_00723 4.3e-170 mleP S Sodium Bile acid symporter family
BLKGCIPE_00724 1e-43 XK27_05745
BLKGCIPE_00725 3.6e-230 cinA 3.5.1.42 S Belongs to the CinA family
BLKGCIPE_00726 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BLKGCIPE_00727 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
BLKGCIPE_00728 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
BLKGCIPE_00729 1.5e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
BLKGCIPE_00731 4.7e-168 fhuR K transcriptional regulator (lysR family)
BLKGCIPE_00732 4.4e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BLKGCIPE_00733 0.0 lmrA V abc transporter atp-binding protein
BLKGCIPE_00734 4.2e-181 mdlB V abc transporter atp-binding protein
BLKGCIPE_00735 1.8e-45 K TetR family transcriptional regulator
BLKGCIPE_00736 1.8e-45
BLKGCIPE_00737 4.4e-119 V CAAX protease self-immunity
BLKGCIPE_00738 3.4e-10
BLKGCIPE_00739 2.2e-19 S Bacterial lipoprotein
BLKGCIPE_00740 1.1e-57 S Protein of unknown function (DUF1722)
BLKGCIPE_00741 1.9e-124 V abc transporter atp-binding protein
BLKGCIPE_00742 0.0 V ABC transporter (Permease
BLKGCIPE_00743 1.3e-120 K transcriptional regulator, MerR family
BLKGCIPE_00744 9.8e-106 dnaQ 2.7.7.7 L DNA polymerase III
BLKGCIPE_00745 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
BLKGCIPE_00746 2.8e-63 XK27_02560 S cog cog2151
BLKGCIPE_00747 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
BLKGCIPE_00748 4.7e-224 ytfP S Flavoprotein
BLKGCIPE_00750 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
BLKGCIPE_00751 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
BLKGCIPE_00752 9.3e-176 ecsB U Bacterial ABC transporter protein EcsB
BLKGCIPE_00753 5.4e-37 ecsA V abc transporter atp-binding protein
BLKGCIPE_00755 7.7e-09
BLKGCIPE_00756 6.9e-142 K sequence-specific DNA binding
BLKGCIPE_00757 2.7e-11 K sequence-specific DNA binding
BLKGCIPE_00758 3e-33 L COG1943 Transposase and inactivated derivatives
BLKGCIPE_00759 6.5e-73 K helix_turn_helix multiple antibiotic resistance protein
BLKGCIPE_00760 7.9e-260 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
BLKGCIPE_00761 1.3e-159 S CHAP domain
BLKGCIPE_00762 8.6e-93 L overlaps another CDS with the same product name
BLKGCIPE_00763 4e-33 L transposition
BLKGCIPE_00764 1.5e-180 coiA 3.6.4.12 S Competence protein
BLKGCIPE_00765 0.0 pepF E oligoendopeptidase F
BLKGCIPE_00766 1.6e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
BLKGCIPE_00767 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
BLKGCIPE_00768 7.8e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
BLKGCIPE_00769 8.7e-84 yxjI S LURP-one-related
BLKGCIPE_00770 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BLKGCIPE_00772 3.3e-234 mntH P H( )-stimulated, divalent metal cation uptake system
BLKGCIPE_00773 8.9e-33 XK27_12190 S protein conserved in bacteria
BLKGCIPE_00775 3.2e-87 bioY S biotin synthase
BLKGCIPE_00776 7.5e-252 yegQ O Peptidase U32
BLKGCIPE_00777 2e-177 yegQ O Peptidase U32
BLKGCIPE_00779 4.2e-69 ytxH S General stress protein
BLKGCIPE_00780 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BLKGCIPE_00781 9.6e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BLKGCIPE_00782 8e-171 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BLKGCIPE_00783 2.2e-41 pspC KT PspC domain
BLKGCIPE_00784 0.0 yhgF K Transcriptional accessory protein
BLKGCIPE_00785 2e-39 ynzC S UPF0291 protein
BLKGCIPE_00786 6.7e-254 cycA E permease
BLKGCIPE_00787 6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
BLKGCIPE_00788 7.9e-236 vicK 2.7.13.3 T Histidine kinase
BLKGCIPE_00789 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BLKGCIPE_00790 6.5e-35 E nucleotide metabolic process
BLKGCIPE_00791 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BLKGCIPE_00792 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
BLKGCIPE_00793 1.5e-219 metE 2.1.1.14 E Methionine synthase
BLKGCIPE_00794 7e-240 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
BLKGCIPE_00795 2.8e-238 hisS 6.1.1.21 J histidyl-tRNA synthetase
BLKGCIPE_00797 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
BLKGCIPE_00798 2.4e-167 XK27_01785 S cog cog1284
BLKGCIPE_00799 7.5e-121 yaaA S Belongs to the UPF0246 family
BLKGCIPE_00800 2.4e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BLKGCIPE_00801 3.5e-88 XK27_10930 K acetyltransferase
BLKGCIPE_00802 7.5e-14
BLKGCIPE_00803 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
BLKGCIPE_00804 6.5e-129 rpsA 1.17.7.4 J ribosomal protein S1
BLKGCIPE_00807 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
BLKGCIPE_00808 4.4e-118 M Pfam SNARE associated Golgi protein
BLKGCIPE_00809 3e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
BLKGCIPE_00810 2.9e-151 yitS S EDD domain protein, DegV family
BLKGCIPE_00811 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
BLKGCIPE_00813 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLKGCIPE_00814 1.6e-25 epuA S DNA-directed RNA polymerase subunit beta
BLKGCIPE_00815 6.5e-154 endA F DNA RNA non-specific endonuclease
BLKGCIPE_00816 2.9e-58
BLKGCIPE_00817 0.0 ctpE P E1-E2 ATPase
BLKGCIPE_00818 1.5e-247 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
BLKGCIPE_00819 2.2e-69 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
BLKGCIPE_00820 3e-87 S Fusaric acid resistance protein-like
BLKGCIPE_00821 2.5e-62 glnR K Transcriptional regulator
BLKGCIPE_00822 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
BLKGCIPE_00823 6.6e-116 pscB M CHAP domain protein
BLKGCIPE_00824 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLKGCIPE_00825 1.5e-33 ykzG S Belongs to the UPF0356 family
BLKGCIPE_00826 3.9e-114 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
BLKGCIPE_00827 2.6e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
BLKGCIPE_00828 1.3e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BLKGCIPE_00829 3e-114 azlC E AzlC protein
BLKGCIPE_00830 1.3e-46 azlD S branched-chain amino acid
BLKGCIPE_00831 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
BLKGCIPE_00832 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
BLKGCIPE_00833 1e-29 rpsT J Binds directly to 16S ribosomal RNA
BLKGCIPE_00834 5.6e-172 coaA 2.7.1.33 F Pantothenic acid kinase
BLKGCIPE_00835 7e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
BLKGCIPE_00836 1.9e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
BLKGCIPE_00837 7.1e-113 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BLKGCIPE_00838 3.1e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
BLKGCIPE_00839 4.7e-191 tcsA S membrane
BLKGCIPE_00840 1.4e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
BLKGCIPE_00841 3.9e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
BLKGCIPE_00842 1.2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
BLKGCIPE_00843 5.8e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
BLKGCIPE_00844 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
BLKGCIPE_00845 6.9e-22 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BLKGCIPE_00846 7.8e-15 rpmJ J Ribosomal protein L36
BLKGCIPE_00847 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BLKGCIPE_00848 1.3e-61 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BLKGCIPE_00849 6.8e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BLKGCIPE_00850 2e-62 rplQ J Ribosomal protein L17
BLKGCIPE_00851 1.7e-226 recJ L Single-strand DNA-specific exonuclease, C terminal domain
BLKGCIPE_00852 1.1e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLKGCIPE_00853 5.1e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BLKGCIPE_00854 1.3e-125 dnaD
BLKGCIPE_00855 4.5e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BLKGCIPE_00857 3.6e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BLKGCIPE_00858 1e-28 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BLKGCIPE_00859 1.3e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
BLKGCIPE_00860 4.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
BLKGCIPE_00861 8.3e-73 argR K Regulates arginine biosynthesis genes
BLKGCIPE_00862 1.8e-301 recN L May be involved in recombinational repair of damaged DNA
BLKGCIPE_00863 2.9e-143 DegV S DegV family
BLKGCIPE_00864 9.1e-265 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
BLKGCIPE_00865 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
BLKGCIPE_00866 1.7e-17 XK27_00735
BLKGCIPE_00867 1.2e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
BLKGCIPE_00868 5.1e-59 rplO J binds to the 23S rRNA
BLKGCIPE_00869 1.9e-23 rpmD J Ribosomal protein L30p/L7e
BLKGCIPE_00870 1e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BLKGCIPE_00871 1.7e-75 S Carbohydrate-binding domain-containing protein Cthe_2159
BLKGCIPE_00872 1.6e-143 P VTC domain
BLKGCIPE_00873 1.3e-167 cpsJ M Glycosyltransferase group 2 family protein
BLKGCIPE_00874 2.6e-62 rplQ J ribosomal protein l17
BLKGCIPE_00875 1.8e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BLKGCIPE_00876 1.1e-56 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BLKGCIPE_00877 1.8e-136 amiD P ABC transporter (Permease
BLKGCIPE_00878 1.6e-202 oppD P Belongs to the ABC transporter superfamily
BLKGCIPE_00879 5e-186 femA 2.3.2.10, 2.3.2.16 V FemAB family
BLKGCIPE_00880 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLKGCIPE_00881 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
BLKGCIPE_00882 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BLKGCIPE_00883 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLKGCIPE_00884 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BLKGCIPE_00885 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BLKGCIPE_00886 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BLKGCIPE_00887 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
BLKGCIPE_00888 1.5e-215 ftsW D Belongs to the SEDS family
BLKGCIPE_00889 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BLKGCIPE_00890 1.9e-105 P ABC transporter (Permease
BLKGCIPE_00891 3e-114 papP P ABC transporter (Permease
BLKGCIPE_00892 2.5e-58 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
BLKGCIPE_00893 1.2e-38 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
BLKGCIPE_00894 1.3e-173 S hydrolase
BLKGCIPE_00895 1.4e-22
BLKGCIPE_00896 6.9e-63 M LysM domain
BLKGCIPE_00897 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
BLKGCIPE_00898 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
BLKGCIPE_00899 8.3e-109 yaaT S stage 0 sporulation protein
BLKGCIPE_00900 1.2e-54 yabA L Involved in initiation control of chromosome replication
BLKGCIPE_00901 4e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BLKGCIPE_00902 4.3e-228 amt P Ammonium Transporter
BLKGCIPE_00903 1.9e-53 glnB K Belongs to the P(II) protein family
BLKGCIPE_00904 8.6e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
BLKGCIPE_00905 3.3e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
BLKGCIPE_00906 1.8e-82 S Bacterial inner membrane protein
BLKGCIPE_00907 8e-114 3.4.17.14, 3.5.1.28 NU amidase activity
BLKGCIPE_00908 7.2e-292 nptA P COG1283 Na phosphate symporter
BLKGCIPE_00909 1.5e-211 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
BLKGCIPE_00910 1.3e-219 S membrane
BLKGCIPE_00911 1.1e-107 magIII L Base excision DNA repair protein, HhH-GPD family
BLKGCIPE_00912 2.3e-263 proWX P ABC transporter
BLKGCIPE_00913 2.2e-54 proV E abc transporter atp-binding protein
BLKGCIPE_00914 1e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
BLKGCIPE_00915 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BLKGCIPE_00916 1.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLKGCIPE_00917 3.2e-136 E Alpha beta hydrolase
BLKGCIPE_00918 1.9e-141 plsC 2.3.1.51 I Acyltransferase
BLKGCIPE_00919 4.3e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
BLKGCIPE_00920 3e-67 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
BLKGCIPE_00921 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
BLKGCIPE_00922 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
BLKGCIPE_00923 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BLKGCIPE_00924 3.7e-111 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BLKGCIPE_00925 3.2e-127 K Psort location Cytoplasmic, score
BLKGCIPE_00926 3.7e-171 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
BLKGCIPE_00927 1.5e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BLKGCIPE_00928 5.2e-142 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BLKGCIPE_00929 1e-35 XK27_00765
BLKGCIPE_00930 2.9e-165 cpsY K Transcriptional regulator
BLKGCIPE_00931 1.5e-186 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
BLKGCIPE_00932 0.0 dnaE 2.7.7.7 L DNA polymerase
BLKGCIPE_00933 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BLKGCIPE_00934 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BLKGCIPE_00935 2.1e-37 ysdA L Membrane
BLKGCIPE_00936 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
BLKGCIPE_00937 4.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLKGCIPE_00938 1.9e-55 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BLKGCIPE_00939 1.9e-181 XK27_08075 M glycosyl transferase family 2
BLKGCIPE_00940 1.2e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
BLKGCIPE_00941 1.6e-241 malC P ABC transporter (Permease
BLKGCIPE_00942 6.9e-181 mdxE G ABC transporter, substratebinding protein
BLKGCIPE_00943 3.4e-169 S CAAX amino terminal protease family protein
BLKGCIPE_00944 2.5e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
BLKGCIPE_00945 8.4e-30 KT response to antibiotic
BLKGCIPE_00949 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BLKGCIPE_00950 3.3e-59 pts33BCA G pts system
BLKGCIPE_00951 1.2e-160 prmA J Ribosomal protein L11 methyltransferase
BLKGCIPE_00952 4.1e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
BLKGCIPE_00953 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
BLKGCIPE_00954 5e-81 nrdI F Belongs to the NrdI family
BLKGCIPE_00955 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BLKGCIPE_00956 6.7e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
BLKGCIPE_00957 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BLKGCIPE_00958 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
BLKGCIPE_00959 7.3e-71 ylbF S Belongs to the UPF0342 family
BLKGCIPE_00960 1.9e-46 ylbG S UPF0298 protein
BLKGCIPE_00961 2.8e-213 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
BLKGCIPE_00962 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
BLKGCIPE_00963 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
BLKGCIPE_00964 3.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
BLKGCIPE_00965 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
BLKGCIPE_00966 7.1e-113 acuB S CBS domain
BLKGCIPE_00967 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
BLKGCIPE_00968 3.2e-107 yvyE 3.4.13.9 S YigZ family
BLKGCIPE_00969 2.9e-111 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
BLKGCIPE_00970 7.4e-121 ybbA S Putative esterase
BLKGCIPE_00971 7.1e-80 Q Methyltransferase domain
BLKGCIPE_00972 3.3e-100 L Phage integrase family
BLKGCIPE_00977 4.9e-25
BLKGCIPE_00980 9.9e-19 S Protein of unknown function (DUF1642)
BLKGCIPE_00981 8.5e-24 S Protein of unknown function (DUF1642)
BLKGCIPE_00982 3e-12 S Protein of unknown function (DUF1642)
BLKGCIPE_00983 1.7e-08
BLKGCIPE_00984 1.3e-78 M Pilin isopeptide linkage domain protein
BLKGCIPE_00985 6.8e-84 mazG FG Mazg nucleotide pyrophosphohydrolase
BLKGCIPE_00988 1.5e-126 L Phage replisome organizer, N-terminal domain protein
BLKGCIPE_00989 9.1e-58 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BLKGCIPE_00990 2.6e-33 S Protein of unknwon function (DUF3310)
BLKGCIPE_00994 2.3e-20
BLKGCIPE_00997 1.4e-61 S ORF6C domain
BLKGCIPE_00998 1.6e-57
BLKGCIPE_01000 1.7e-21 S Domain of unknown function (DUF4145)
BLKGCIPE_01003 2e-45 ps115 K Transcriptional regulator
BLKGCIPE_01004 6.9e-31 S Pfam:Peptidase_M78
BLKGCIPE_01005 2.9e-164 sip L Belongs to the 'phage' integrase family
BLKGCIPE_01007 1.3e-80
BLKGCIPE_01009 3.7e-76
BLKGCIPE_01010 6.8e-81 S peptidoglycan catabolic process
BLKGCIPE_01011 1.6e-36 hol S COG5546 Small integral membrane protein
BLKGCIPE_01013 1.1e-52
BLKGCIPE_01015 0.0 S Phage minor structural protein
BLKGCIPE_01016 3.7e-128
BLKGCIPE_01017 0.0 D Phage-related minor tail protein
BLKGCIPE_01021 2.7e-50 S Phage tail tube protein
BLKGCIPE_01022 1e-63
BLKGCIPE_01023 3.2e-15
BLKGCIPE_01024 8.3e-66
BLKGCIPE_01026 1.1e-44
BLKGCIPE_01027 6.2e-194 S Phage capsid family
BLKGCIPE_01028 9.1e-136 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
BLKGCIPE_01029 1.1e-214 S portal protein
BLKGCIPE_01031 0.0 L Terminase
BLKGCIPE_01032 1.7e-54
BLKGCIPE_01033 3.4e-94 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BLKGCIPE_01034 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BLKGCIPE_01035 7.2e-98 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BLKGCIPE_01037 1.8e-102 pyrP F uracil Permease
BLKGCIPE_01038 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
BLKGCIPE_01039 4.6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
BLKGCIPE_01040 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
BLKGCIPE_01041 1.7e-126 2.1.1.223 S Putative SAM-dependent methyltransferase
BLKGCIPE_01042 1.4e-181 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLKGCIPE_01043 1.1e-122 macB V ABC transporter, ATP-binding protein
BLKGCIPE_01044 4.3e-237 vex3 V Efflux ABC transporter, permease protein
BLKGCIPE_01045 1.9e-107 vex2 V abc transporter atp-binding protein
BLKGCIPE_01046 2.5e-91 Q Nodulation protein S (NodS)
BLKGCIPE_01047 1.9e-46 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLKGCIPE_01048 3.2e-203 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLKGCIPE_01049 3.5e-51 amiA E ABC transporter, substrate-binding protein, family 5
BLKGCIPE_01050 2.1e-277 amiC P ABC transporter (Permease
BLKGCIPE_01051 1.1e-139 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
BLKGCIPE_01052 2.9e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
BLKGCIPE_01053 8.8e-187 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BLKGCIPE_01054 7.8e-219 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BLKGCIPE_01055 1.5e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
BLKGCIPE_01056 1.9e-206 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
BLKGCIPE_01057 2.7e-128 yxkH G deacetylase
BLKGCIPE_01058 1.5e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
BLKGCIPE_01059 1.6e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
BLKGCIPE_01060 4.3e-121 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
BLKGCIPE_01061 1e-176 bglC K Transcriptional regulator
BLKGCIPE_01062 2.8e-67 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BLKGCIPE_01063 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
BLKGCIPE_01064 3.1e-69 argR K Regulates arginine biosynthesis genes
BLKGCIPE_01065 1.9e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
BLKGCIPE_01066 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BLKGCIPE_01067 1.9e-77 S Protein of unknown function (DUF3021)
BLKGCIPE_01068 3.2e-69 K LytTr DNA-binding domain
BLKGCIPE_01070 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BLKGCIPE_01072 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
BLKGCIPE_01073 1.9e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
BLKGCIPE_01074 2.5e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BLKGCIPE_01075 6.4e-37 yeeD O sulfur carrier activity
BLKGCIPE_01076 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
BLKGCIPE_01077 6.1e-162 XK27_05670 S Putative esterase
BLKGCIPE_01078 2.7e-153 XK27_05675 S Esterase
BLKGCIPE_01079 9.9e-227 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
BLKGCIPE_01080 3.2e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
BLKGCIPE_01081 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
BLKGCIPE_01082 0.0 uup S abc transporter atp-binding protein
BLKGCIPE_01083 5.3e-34 MA20_06245 S yiaA/B two helix domain
BLKGCIPE_01084 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
BLKGCIPE_01085 6e-117 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
BLKGCIPE_01086 4.5e-130 V Psort location CytoplasmicMembrane, score
BLKGCIPE_01087 4.1e-119 skfE V abc transporter atp-binding protein
BLKGCIPE_01088 5.6e-62 yvoA_1 K Transcriptional
BLKGCIPE_01089 1e-145 supH S overlaps another CDS with the same product name
BLKGCIPE_01090 1e-145 XK27_02985 S overlaps another CDS with the same product name
BLKGCIPE_01091 1.8e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BLKGCIPE_01092 5.7e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
BLKGCIPE_01093 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
BLKGCIPE_01094 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BLKGCIPE_01095 1.6e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BLKGCIPE_01096 4.9e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BLKGCIPE_01097 4.8e-137 stp 3.1.3.16 T phosphatase
BLKGCIPE_01098 2.3e-289 prkC 2.7.11.1 KLT serine threonine protein kinase
BLKGCIPE_01099 3.8e-102 kcsA P Ion transport protein
BLKGCIPE_01100 3.3e-116 yvqF S Membrane
BLKGCIPE_01101 1.9e-170 vraS 2.7.13.3 T Histidine kinase
BLKGCIPE_01102 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BLKGCIPE_01105 9.9e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BLKGCIPE_01106 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
BLKGCIPE_01107 6.6e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
BLKGCIPE_01108 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
BLKGCIPE_01109 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BLKGCIPE_01110 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BLKGCIPE_01111 1.1e-185 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BLKGCIPE_01112 5.7e-187 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
BLKGCIPE_01113 8.3e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
BLKGCIPE_01114 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
BLKGCIPE_01115 5.3e-101 2.3.1.128 K Acetyltransferase GNAT Family
BLKGCIPE_01116 1.5e-286 S Protein of unknown function (DUF3114)
BLKGCIPE_01118 2e-97 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
BLKGCIPE_01119 2.4e-101 yjbK S Adenylate cyclase
BLKGCIPE_01120 6.7e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
BLKGCIPE_01121 8.1e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
BLKGCIPE_01122 1.2e-165 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
BLKGCIPE_01123 1e-38 gcvR T UPF0237 protein
BLKGCIPE_01124 3e-234 capA M Bacterial capsule synthesis protein
BLKGCIPE_01125 2.5e-231 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BLKGCIPE_01127 4.2e-62 phoU P Plays a role in the regulation of phosphate uptake
BLKGCIPE_01128 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BLKGCIPE_01129 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
BLKGCIPE_01130 3.1e-125 S Protein of unknown function (DUF554)
BLKGCIPE_01131 4.4e-132 ecsA_2 V abc transporter atp-binding protein
BLKGCIPE_01132 6.1e-146 V 'abc transporter, ATP-binding protein
BLKGCIPE_01134 3.5e-212 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BLKGCIPE_01135 1.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BLKGCIPE_01136 5.8e-55 S TM2 domain
BLKGCIPE_01137 5.5e-44
BLKGCIPE_01139 1.5e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
BLKGCIPE_01140 1.9e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BLKGCIPE_01141 1.4e-142 cmpC S abc transporter atp-binding protein
BLKGCIPE_01142 0.0 WQ51_06230 S ABC transporter
BLKGCIPE_01143 3.3e-159 L Replication initiation factor
BLKGCIPE_01144 1.9e-18 S Domain of unknown function (DUF3173)
BLKGCIPE_01145 1.8e-72 copY K negative regulation of transcription, DNA-templated
BLKGCIPE_01146 9.2e-164 EGP Major facilitator Superfamily
BLKGCIPE_01147 8.5e-101 S SIR2-like domain
BLKGCIPE_01148 1.9e-167 S cog cog0433
BLKGCIPE_01149 1.7e-85 ccl S cog cog4708
BLKGCIPE_01150 4.8e-163 rbn E Belongs to the UPF0761 family
BLKGCIPE_01151 4.2e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
BLKGCIPE_01152 3e-232 ytoI K transcriptional regulator containing CBS domains
BLKGCIPE_01153 2.8e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
BLKGCIPE_01154 6.1e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLKGCIPE_01155 1.4e-147 T PhoQ Sensor
BLKGCIPE_01156 1.2e-25 WQ51_00785
BLKGCIPE_01157 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
BLKGCIPE_01158 1.5e-219 ywbD 2.1.1.191 J Methyltransferase
BLKGCIPE_01159 1.5e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
BLKGCIPE_01160 1.3e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BLKGCIPE_01161 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BLKGCIPE_01162 9.9e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BLKGCIPE_01163 8.3e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
BLKGCIPE_01164 4.2e-53 yheA S Belongs to the UPF0342 family
BLKGCIPE_01165 2.7e-38 K Acetyltransferase (GNAT) family
BLKGCIPE_01166 5.3e-110 2.7.6.5 S Region found in RelA / SpoT proteins
BLKGCIPE_01167 1.7e-117 T response regulator
BLKGCIPE_01168 2.9e-213 sptS 2.7.13.3 T Histidine kinase
BLKGCIPE_01169 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
BLKGCIPE_01170 1.7e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
BLKGCIPE_01171 1e-159 cvfB S Protein conserved in bacteria
BLKGCIPE_01172 3.7e-34 yozE S Belongs to the UPF0346 family
BLKGCIPE_01173 3.5e-128 sip M LysM domain protein
BLKGCIPE_01174 4e-190 phoH T phosphate starvation-inducible protein PhoH
BLKGCIPE_01177 1e-134 glcR K transcriptional regulator (DeoR family)
BLKGCIPE_01178 7.8e-146 cof S Sucrose-6F-phosphate phosphohydrolase
BLKGCIPE_01179 2.1e-69 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
BLKGCIPE_01180 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BLKGCIPE_01181 2.5e-258 S phospholipase Carboxylesterase
BLKGCIPE_01182 5.7e-200 yurR 1.4.5.1 E oxidoreductase
BLKGCIPE_01183 4e-145 zupT P Mediates zinc uptake. May also transport other divalent cations
BLKGCIPE_01184 1.1e-144 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BLKGCIPE_01185 1.7e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
BLKGCIPE_01186 1.6e-65 gtrA S GtrA-like protein
BLKGCIPE_01187 2.8e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLKGCIPE_01188 2.4e-122 ybbR S Protein conserved in bacteria
BLKGCIPE_01189 2.7e-151 gst O Glutathione S-transferase
BLKGCIPE_01190 2.5e-186 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BLKGCIPE_01191 1.9e-109 tdk 2.7.1.21 F thymidine kinase
BLKGCIPE_01192 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BLKGCIPE_01193 1.4e-142 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
BLKGCIPE_01194 3.7e-100 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
BLKGCIPE_01195 1.3e-62 XK27_05710 K Acetyltransferase (GNAT) domain
BLKGCIPE_01196 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BLKGCIPE_01197 5.5e-178 ndpA S 37-kD nucleoid-associated bacterial protein
BLKGCIPE_01198 4.1e-99 pvaA M lytic transglycosylase activity
BLKGCIPE_01199 2.3e-188
BLKGCIPE_01200 6.5e-14 S Sigma-70, region 4
BLKGCIPE_01201 4.8e-43
BLKGCIPE_01202 1.1e-192 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
BLKGCIPE_01203 2.7e-53
BLKGCIPE_01204 1e-91 S Plasmid replication protein
BLKGCIPE_01205 1.5e-18 S MerR HTH family regulatory protein
BLKGCIPE_01206 5.2e-213 sip L Phage integrase, N-terminal SAM-like domain
BLKGCIPE_01207 2.5e-07
BLKGCIPE_01210 7.5e-117 nudL L hydrolase
BLKGCIPE_01211 1.8e-53 K transcriptional regulator, PadR family
BLKGCIPE_01212 1.4e-104 K Transcriptional regulator, TetR family
BLKGCIPE_01213 5.9e-61 S Protein of unknown function with HXXEE motif
BLKGCIPE_01214 9e-294 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
BLKGCIPE_01215 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BLKGCIPE_01216 1.3e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BLKGCIPE_01217 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
BLKGCIPE_01218 0.0 ydaO E amino acid
BLKGCIPE_01219 9.2e-234 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BLKGCIPE_01220 1.5e-36 ylqC L Belongs to the UPF0109 family
BLKGCIPE_01221 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
BLKGCIPE_01223 7.8e-198 2.7.13.3 T GHKL domain
BLKGCIPE_01224 8.9e-119 agrA KT phosphorelay signal transduction system
BLKGCIPE_01225 6.6e-300 treC 3.2.1.93 GH13 G COG0366 Glycosidases
BLKGCIPE_01226 3e-38 ptsH G phosphocarrier protein Hpr
BLKGCIPE_01227 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
BLKGCIPE_01228 2.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
BLKGCIPE_01229 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BLKGCIPE_01230 1.9e-33 nrdH O Glutaredoxin
BLKGCIPE_01231 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLKGCIPE_01232 8.5e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLKGCIPE_01233 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BLKGCIPE_01234 2.7e-136 divIVA D Cell division initiation protein
BLKGCIPE_01235 5e-145 ylmH S conserved protein, contains S4-like domain
BLKGCIPE_01236 6.5e-30 yggT D integral membrane protein
BLKGCIPE_01237 3.2e-101 sepF D cell septum assembly
BLKGCIPE_01238 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BLKGCIPE_01239 3.2e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BLKGCIPE_01240 2e-242 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
BLKGCIPE_01241 3.5e-136 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
BLKGCIPE_01242 5.6e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLKGCIPE_01243 1e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BLKGCIPE_01245 0.0 typA T GTP-binding protein TypA
BLKGCIPE_01246 1.9e-178 glk 2.7.1.2 G Glucokinase
BLKGCIPE_01247 2.4e-27 yqgQ S protein conserved in bacteria
BLKGCIPE_01248 6.9e-80 perR P Belongs to the Fur family
BLKGCIPE_01249 9.3e-92 dps P Belongs to the Dps family
BLKGCIPE_01250 1.7e-114 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
BLKGCIPE_01251 3.6e-172 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
BLKGCIPE_01252 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
BLKGCIPE_01253 1.9e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
BLKGCIPE_01254 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BLKGCIPE_01255 4.8e-64 S Domain of unknown function (DUF4430)
BLKGCIPE_01256 6.7e-73 S Psort location CytoplasmicMembrane, score
BLKGCIPE_01257 2e-269 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLKGCIPE_01258 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BLKGCIPE_01259 5.1e-22 K Transcriptional
BLKGCIPE_01261 4.1e-207 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
BLKGCIPE_01262 2e-146 yidA S hydrolases of the HAD superfamily
BLKGCIPE_01263 4e-156 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
BLKGCIPE_01264 2.4e-130 XK27_00120 2.4.2.3 F Phosphorylase superfamily
BLKGCIPE_01265 5.3e-68 ywiB S Domain of unknown function (DUF1934)
BLKGCIPE_01266 0.0 pacL 3.6.3.8 P cation transport ATPase
BLKGCIPE_01267 7.7e-132 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
BLKGCIPE_01268 2.5e-62 manO S protein conserved in bacteria
BLKGCIPE_01269 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
BLKGCIPE_01270 2.6e-117 manM G pts system
BLKGCIPE_01271 4.9e-174 manL 2.7.1.191 G pts system
BLKGCIPE_01272 2e-67 manO S Protein conserved in bacteria
BLKGCIPE_01273 3.4e-158 manN G PTS system mannose fructose sorbose family IID component
BLKGCIPE_01274 5.7e-133 manY G pts system
BLKGCIPE_01275 6.2e-169 manL 2.7.1.191 G pts system
BLKGCIPE_01276 9.6e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
BLKGCIPE_01277 6.4e-17 yhaI L Membrane
BLKGCIPE_01278 1.1e-13 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLKGCIPE_01279 9.6e-73 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLKGCIPE_01280 2.2e-73 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLKGCIPE_01282 2e-157 xth 3.1.11.2 L exodeoxyribonuclease III
BLKGCIPE_01283 5.8e-72 S QueT transporter
BLKGCIPE_01285 1.1e-173 yfjR K regulation of single-species biofilm formation
BLKGCIPE_01287 5.8e-40
BLKGCIPE_01288 0.0 comEC S Competence protein ComEC
BLKGCIPE_01289 4.4e-101 IQ reductase
BLKGCIPE_01290 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
BLKGCIPE_01291 1.5e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
BLKGCIPE_01292 6.6e-285 S Psort location CytoplasmicMembrane, score
BLKGCIPE_01293 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
BLKGCIPE_01294 3.3e-74 K DNA-binding transcription factor activity
BLKGCIPE_01295 0.0 lmrA1 V abc transporter atp-binding protein
BLKGCIPE_01296 0.0 lmrA2 V abc transporter atp-binding protein
BLKGCIPE_01297 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BLKGCIPE_01298 1.3e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BLKGCIPE_01299 1.3e-150 I Alpha/beta hydrolase family
BLKGCIPE_01300 6.6e-08
BLKGCIPE_01301 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
BLKGCIPE_01302 1.4e-78 feoA P FeoA domain protein
BLKGCIPE_01303 6.4e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
BLKGCIPE_01304 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
BLKGCIPE_01305 1e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
BLKGCIPE_01308 1.6e-103
BLKGCIPE_01310 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
BLKGCIPE_01311 1.6e-44 yoeB S Addiction module toxin, Txe YoeB family
BLKGCIPE_01312 3.4e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
BLKGCIPE_01313 2.2e-196 ylbM S Belongs to the UPF0348 family
BLKGCIPE_01314 2.9e-139 yqeM Q Methyltransferase domain protein
BLKGCIPE_01315 7.9e-255 L Transposase
BLKGCIPE_01316 1.1e-83 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
BLKGCIPE_01317 4e-122
BLKGCIPE_01319 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
BLKGCIPE_01320 2.7e-88 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
BLKGCIPE_01321 6.9e-305 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BLKGCIPE_01322 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BLKGCIPE_01323 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BLKGCIPE_01324 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
BLKGCIPE_01325 2.1e-129 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLKGCIPE_01326 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
BLKGCIPE_01327 2.2e-101 ybhL S Belongs to the BI1 family
BLKGCIPE_01328 5.5e-12 ycdA S Domain of unknown function (DUF4352)
BLKGCIPE_01329 6.2e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
BLKGCIPE_01330 1.4e-90 K transcriptional regulator
BLKGCIPE_01331 1.6e-36 yneF S UPF0154 protein
BLKGCIPE_01332 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
BLKGCIPE_01333 3.5e-185 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BLKGCIPE_01334 1.1e-97 XK27_09740 S Phosphoesterase
BLKGCIPE_01335 8.3e-87 ykuL S CBS domain
BLKGCIPE_01336 1.7e-134 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
BLKGCIPE_01337 1e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BLKGCIPE_01338 6.5e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BLKGCIPE_01339 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BLKGCIPE_01340 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
BLKGCIPE_01341 9.3e-259 trkH P Cation transport protein
BLKGCIPE_01342 1.2e-247 trkA P Potassium transporter peripheral membrane component
BLKGCIPE_01343 1.4e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
BLKGCIPE_01344 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BLKGCIPE_01345 2.8e-106 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
BLKGCIPE_01346 7.8e-155 K sequence-specific DNA binding
BLKGCIPE_01347 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BLKGCIPE_01348 6.4e-54 yhaI L Membrane
BLKGCIPE_01349 3.6e-94 S Domain of unknown function (DUF4173)
BLKGCIPE_01350 1.5e-94 ureI S AmiS/UreI family transporter
BLKGCIPE_01351 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
BLKGCIPE_01352 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
BLKGCIPE_01353 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
BLKGCIPE_01354 2.5e-77 ureE O enzyme active site formation
BLKGCIPE_01355 2.6e-129 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
BLKGCIPE_01356 1.4e-110 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BLKGCIPE_01357 8.6e-156 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
BLKGCIPE_01358 4.5e-172 cbiM P biosynthesis protein CbiM
BLKGCIPE_01359 1.6e-68 asp3 S Accessory Sec system protein Asp3
BLKGCIPE_01360 1.5e-302 asp2 3.4.11.5 S Accessory Sec system protein Asp2
BLKGCIPE_01361 6.2e-309 asp1 S Accessory Sec system protein Asp1
BLKGCIPE_01362 3.9e-165 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
BLKGCIPE_01363 5.8e-241 M family 8
BLKGCIPE_01364 4.8e-86 M cog cog1442
BLKGCIPE_01365 1.3e-218 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
BLKGCIPE_01366 8.4e-304 yloV S kinase related to dihydroxyacetone kinase
BLKGCIPE_01367 1.4e-57 asp S cog cog1302
BLKGCIPE_01368 4.6e-225 norN V Mate efflux family protein
BLKGCIPE_01369 1.7e-276 thrC 4.2.3.1 E Threonine synthase
BLKGCIPE_01372 7.4e-91 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
BLKGCIPE_01373 1.8e-104 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
BLKGCIPE_01374 8.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BLKGCIPE_01375 1.1e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
BLKGCIPE_01376 0.0 lacS G transporter
BLKGCIPE_01377 0.0 lacL 3.2.1.23 G -beta-galactosidase
BLKGCIPE_01378 5.5e-175 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BLKGCIPE_01379 4e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
BLKGCIPE_01380 2.3e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
BLKGCIPE_01381 0.0 U protein secretion
BLKGCIPE_01382 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BLKGCIPE_01383 2e-26
BLKGCIPE_01384 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
BLKGCIPE_01385 3.3e-62 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
BLKGCIPE_01386 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
BLKGCIPE_01387 1.4e-105 artQ P ABC transporter (Permease
BLKGCIPE_01388 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
BLKGCIPE_01389 7.9e-157 aatB ET ABC transporter substrate-binding protein
BLKGCIPE_01390 1.5e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLKGCIPE_01391 1.4e-49
BLKGCIPE_01392 6e-45
BLKGCIPE_01393 1e-187 adhP 1.1.1.1 C alcohol dehydrogenase
BLKGCIPE_01394 6.5e-102 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
BLKGCIPE_01395 1.9e-07
BLKGCIPE_01400 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BLKGCIPE_01401 4.3e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
BLKGCIPE_01402 5.5e-36 XK27_02060 S Transglycosylase associated protein
BLKGCIPE_01403 3.9e-72 badR K Transcriptional regulator, marr family
BLKGCIPE_01404 3.2e-95 S reductase
BLKGCIPE_01405 1.4e-236 GM domain, Protein
BLKGCIPE_01406 4.2e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
BLKGCIPE_01407 0.0 sbcC L ATPase involved in DNA repair
BLKGCIPE_01408 6.9e-09
BLKGCIPE_01410 3e-185 desK 2.7.13.3 T Histidine kinase
BLKGCIPE_01411 5.4e-98 yvfS V ABC-2 type transporter
BLKGCIPE_01412 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
BLKGCIPE_01413 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
BLKGCIPE_01414 9.3e-275 argH 4.3.2.1 E Argininosuccinate lyase
BLKGCIPE_01415 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
BLKGCIPE_01416 1.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BLKGCIPE_01417 1.6e-180 jag S RNA-binding protein
BLKGCIPE_01418 6.9e-107 K Transcriptional regulator
BLKGCIPE_01419 1.5e-103 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
BLKGCIPE_01420 3.4e-14 rpmH J Ribosomal protein L34
BLKGCIPE_01421 2.4e-107 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BLKGCIPE_01422 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
BLKGCIPE_01423 6.9e-156 pstS P phosphate
BLKGCIPE_01424 1.6e-249 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
BLKGCIPE_01425 1.3e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
BLKGCIPE_01426 1e-44 yktA S Belongs to the UPF0223 family
BLKGCIPE_01427 1.6e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
BLKGCIPE_01428 1.8e-170 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
BLKGCIPE_01429 1.9e-147 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BLKGCIPE_01430 1.8e-68 XK27_04775 S hemerythrin HHE cation binding domain
BLKGCIPE_01431 3.2e-52 manA 5.3.1.8 G mannose-6-phosphate isomerase
BLKGCIPE_01433 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BLKGCIPE_01434 4.2e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BLKGCIPE_01435 1.9e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BLKGCIPE_01436 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
BLKGCIPE_01437 2.2e-191 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BLKGCIPE_01438 3.2e-141 cppA E CppA N-terminal
BLKGCIPE_01439 1.3e-100 V CAAX protease self-immunity
BLKGCIPE_01440 5.7e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
BLKGCIPE_01441 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
BLKGCIPE_01442 6.7e-07
BLKGCIPE_01444 5.4e-44 spiA K sequence-specific DNA binding
BLKGCIPE_01445 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BLKGCIPE_01446 2e-83 comFC K competence protein
BLKGCIPE_01447 3.8e-91 panT S Psort location CytoplasmicMembrane, score
BLKGCIPE_01448 1.2e-92 panT S ECF transporter, substrate-specific component
BLKGCIPE_01449 4.8e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BLKGCIPE_01450 1e-114 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
BLKGCIPE_01451 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
BLKGCIPE_01452 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BLKGCIPE_01453 6.6e-241 T PhoQ Sensor
BLKGCIPE_01454 1.3e-66 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
BLKGCIPE_01455 1.9e-227 rodA D Belongs to the SEDS family
BLKGCIPE_01456 5.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BLKGCIPE_01457 3.1e-113 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
BLKGCIPE_01458 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
BLKGCIPE_01459 2.5e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
BLKGCIPE_01460 2.6e-65 GnaT 2.5.1.16 K acetyltransferase
BLKGCIPE_01461 6.6e-111 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
BLKGCIPE_01462 6.4e-18 S Domain of unknown function (DUF4649)
BLKGCIPE_01463 2.8e-177 XK27_08835 S ABC transporter substrate binding protein
BLKGCIPE_01464 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
BLKGCIPE_01465 2.6e-135 XK27_08845 S abc transporter atp-binding protein
BLKGCIPE_01466 1.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLKGCIPE_01467 8.6e-150 estA CE1 S Esterase
BLKGCIPE_01469 0.0 XK27_10405 S Bacterial membrane protein YfhO
BLKGCIPE_01470 5.1e-306 ybiT S abc transporter atp-binding protein
BLKGCIPE_01471 2.2e-154 yvjA S membrane
BLKGCIPE_01472 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
BLKGCIPE_01473 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
BLKGCIPE_01474 1e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BLKGCIPE_01475 3.1e-60 yaaA S S4 domain protein YaaA
BLKGCIPE_01476 4.8e-235 ymfF S Peptidase M16
BLKGCIPE_01477 3.1e-242 ymfH S Peptidase M16
BLKGCIPE_01478 3.3e-134 S sequence-specific DNA binding
BLKGCIPE_01479 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BLKGCIPE_01480 1.3e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BLKGCIPE_01481 4.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BLKGCIPE_01482 8.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BLKGCIPE_01483 2e-71 lytE M LysM domain protein
BLKGCIPE_01484 1.4e-58 isaA GH23 M Immunodominant staphylococcal antigen A
BLKGCIPE_01485 2.3e-304 S Bacterial membrane protein, YfhO
BLKGCIPE_01486 1.9e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
BLKGCIPE_01487 2.4e-99 yvbG U UPF0056 membrane protein
BLKGCIPE_01488 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
BLKGCIPE_01489 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
BLKGCIPE_01490 2.2e-73 rplI J binds to the 23S rRNA
BLKGCIPE_01491 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
BLKGCIPE_01492 1.8e-47 veg S Biofilm formation stimulator VEG
BLKGCIPE_01493 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BLKGCIPE_01494 2.5e-65 L Transposase (IS116 IS110 IS902 family)
BLKGCIPE_01495 7.1e-141 L PFAM transposase IS116 IS110 IS902 family
BLKGCIPE_01496 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BLKGCIPE_01497 2.5e-167 corA P COG0598 Mg2 and Co2 transporters
BLKGCIPE_01498 2.6e-123 XK27_01040 S Protein of unknown function (DUF1129)
BLKGCIPE_01500 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BLKGCIPE_01501 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BLKGCIPE_01502 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
BLKGCIPE_01503 8.1e-196 mccF V LD-carboxypeptidase
BLKGCIPE_01504 9.2e-300 O MreB/Mbl protein
BLKGCIPE_01506 1.1e-144 V Psort location CytoplasmicMembrane, score
BLKGCIPE_01509 1.3e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
BLKGCIPE_01512 8.3e-31 yozG K Transcriptional regulator
BLKGCIPE_01513 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
BLKGCIPE_01514 2.7e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
BLKGCIPE_01515 4.7e-148 cah 4.2.1.1 P carbonic anhydrase
BLKGCIPE_01516 6.2e-76 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BLKGCIPE_01517 2.1e-117 agrA KT response regulator
BLKGCIPE_01519 1e-57 arsC 1.20.4.1 P Belongs to the ArsC family
BLKGCIPE_01520 7.8e-72 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
BLKGCIPE_01521 7.4e-222 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLKGCIPE_01522 1e-104 wecD M Acetyltransferase (GNAT) domain
BLKGCIPE_01523 3.9e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BLKGCIPE_01524 5.5e-161 GK ROK family
BLKGCIPE_01525 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
BLKGCIPE_01526 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
BLKGCIPE_01527 3.7e-60 potD P spermidine putrescine ABC transporter
BLKGCIPE_01528 2.2e-232 hsdM 2.1.1.72 V HsdM N-terminal domain
BLKGCIPE_01529 8.8e-87 2.1.1.72, 3.1.21.3 L Type I restriction modification DNA specificity domain
BLKGCIPE_01530 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
BLKGCIPE_01531 2.2e-292 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BLKGCIPE_01532 1.7e-99 pncA Q isochorismatase
BLKGCIPE_01533 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BLKGCIPE_01534 1.5e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
BLKGCIPE_01535 9e-75 XK27_03180 T universal stress protein
BLKGCIPE_01537 4.4e-73 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BLKGCIPE_01538 0.0 XK27_09800 I Acyltransferase
BLKGCIPE_01539 9.7e-36 XK27_09805 S MORN repeat protein
BLKGCIPE_01540 1.4e-77 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLKGCIPE_01541 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BLKGCIPE_01542 4.8e-93 adk 2.7.4.3 F topology modulation protein
BLKGCIPE_01544 5.4e-151 yeiH S Conserved hypothetical protein 698
BLKGCIPE_01545 0.0 zmpB M signal peptide protein, YSIRK family
BLKGCIPE_01546 1.6e-65 lytE M LysM domain
BLKGCIPE_01547 8.5e-122 sdaAB 4.3.1.17 E L-serine dehydratase
BLKGCIPE_01548 2.1e-152 sdaAA 4.3.1.17 E L-serine dehydratase
BLKGCIPE_01549 3.8e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
BLKGCIPE_01550 0.0 pepN 3.4.11.2 E aminopeptidase
BLKGCIPE_01551 1.7e-34 phoU P Plays a role in the regulation of phosphate uptake
BLKGCIPE_01552 2.6e-217 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BLKGCIPE_01554 1.2e-11
BLKGCIPE_01555 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BLKGCIPE_01556 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
BLKGCIPE_01557 4.8e-16 S Protein of unknown function (DUF2969)
BLKGCIPE_01560 2.9e-195 yceA S Belongs to the UPF0176 family
BLKGCIPE_01561 1.5e-119 sagI S ABC-2 type transporter
BLKGCIPE_01562 4.2e-164 V ABC transporter
BLKGCIPE_01563 1.7e-128 rr02 KT response regulator
BLKGCIPE_01564 7.7e-212 T signal transduction protein with a C-terminal ATPase domain
BLKGCIPE_01565 8.9e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
BLKGCIPE_01566 7.3e-32 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BLKGCIPE_01567 2e-97 mip S hydroperoxide reductase activity
BLKGCIPE_01568 1e-201 I acyl-CoA dehydrogenase
BLKGCIPE_01569 6.7e-149 ydiA P C4-dicarboxylate transporter malic acid transport
BLKGCIPE_01570 2.6e-245 msrR K Transcriptional regulator
BLKGCIPE_01571 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
BLKGCIPE_01572 4.5e-80 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BLKGCIPE_01573 9.1e-139 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
BLKGCIPE_01574 1.4e-150 XK27_08360 S EDD domain protein, DegV family
BLKGCIPE_01575 5e-63 WQ51_03320 S cog cog4835
BLKGCIPE_01576 7.2e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLKGCIPE_01577 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
BLKGCIPE_01578 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
BLKGCIPE_01579 7.1e-95 2.3.1.128 K acetyltransferase
BLKGCIPE_01580 6.7e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
BLKGCIPE_01581 3.1e-217 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
BLKGCIPE_01582 3.3e-115 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
BLKGCIPE_01583 2.3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
BLKGCIPE_01584 9.2e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
BLKGCIPE_01585 1.6e-169 rmuC S RmuC domain protein
BLKGCIPE_01586 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
BLKGCIPE_01587 4e-142 purR 2.4.2.7 F operon repressor
BLKGCIPE_01588 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BLKGCIPE_01589 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
BLKGCIPE_01590 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BLKGCIPE_01591 2.2e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
BLKGCIPE_01592 1.9e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BLKGCIPE_01593 1.6e-64
BLKGCIPE_01594 3e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
BLKGCIPE_01595 1.4e-98 yqeG S hydrolase of the HAD superfamily
BLKGCIPE_01596 1.2e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)