ORF_ID e_value Gene_name EC_number CAZy COGs Description
HFHCMLFP_00001 1.2e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFHCMLFP_00002 5.2e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFHCMLFP_00003 1.7e-31 yaaA S S4 domain protein YaaA
HFHCMLFP_00004 2.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFHCMLFP_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFHCMLFP_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFHCMLFP_00007 2.3e-125 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HFHCMLFP_00008 8.5e-75 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFHCMLFP_00009 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HFHCMLFP_00010 8.5e-65 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFHCMLFP_00011 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFHCMLFP_00012 5.6e-283 cydA 1.10.3.14 C Cytochrome bd terminal oxidase subunit I
HFHCMLFP_00013 2.6e-178 cydB 1.10.3.14 C Cytochrome bd terminal oxidase subunit II
HFHCMLFP_00014 4.2e-29
HFHCMLFP_00015 3.4e-106 S Protein of unknown function (DUF1211)
HFHCMLFP_00016 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00018 1e-140 S CAAX protease self-immunity
HFHCMLFP_00021 4.7e-110 usp 3.5.1.28 CBM50 D CHAP domain
HFHCMLFP_00022 0.0 ylbB V ABC transporter permease
HFHCMLFP_00023 2.8e-128 macB V ABC transporter, ATP-binding protein
HFHCMLFP_00024 7.5e-100 K transcriptional regulator
HFHCMLFP_00025 5.4e-155 supH G Sucrose-6F-phosphate phosphohydrolase
HFHCMLFP_00026 2.1e-49
HFHCMLFP_00029 0.0 ybfG M peptidoglycan-binding domain-containing protein
HFHCMLFP_00030 5.4e-30 ybfG M peptidoglycan-binding domain-containing protein
HFHCMLFP_00031 4.7e-124 S membrane transporter protein
HFHCMLFP_00032 4.7e-95 S Protein of unknown function (DUF1211)
HFHCMLFP_00033 4.5e-163 corA P CorA-like Mg2+ transporter protein
HFHCMLFP_00034 2.6e-112 K Bacterial regulatory proteins, tetR family
HFHCMLFP_00036 3.4e-242 mntH P H( )-stimulated, divalent metal cation uptake system
HFHCMLFP_00038 2.1e-287 pipD E Dipeptidase
HFHCMLFP_00039 1.1e-105 S Membrane
HFHCMLFP_00040 1.1e-102
HFHCMLFP_00041 2.4e-54
HFHCMLFP_00042 3.6e-20 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HFHCMLFP_00043 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00044 1.1e-43 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HFHCMLFP_00045 1.6e-76
HFHCMLFP_00046 3.4e-121 azlC E branched-chain amino acid
HFHCMLFP_00047 7.3e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HFHCMLFP_00049 5.1e-28
HFHCMLFP_00050 2.5e-144 S CAAX protease self-immunity
HFHCMLFP_00051 1.3e-114 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HFHCMLFP_00052 2.2e-125 kdgR K FCD domain
HFHCMLFP_00054 2.5e-55
HFHCMLFP_00055 2.3e-162 K Transcriptional activator, Rgg GadR MutR family
HFHCMLFP_00056 3.7e-285 V ABC-type multidrug transport system, ATPase and permease components
HFHCMLFP_00057 5e-23
HFHCMLFP_00059 2e-242 EGP Major facilitator Superfamily
HFHCMLFP_00060 4.2e-50 K TRANSCRIPTIONal
HFHCMLFP_00061 0.0 ydgH S MMPL family
HFHCMLFP_00062 7.4e-109 K Tetracycline repressor, C-terminal all-alpha domain
HFHCMLFP_00064 3.3e-110 opuCD P Binding-protein-dependent transport system inner membrane component
HFHCMLFP_00065 3.3e-172 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFHCMLFP_00066 1e-105 opuCB E ABC transporter permease
HFHCMLFP_00067 1.3e-216 opuCA 2.7.7.7 E ABC transporter, ATP-binding protein
HFHCMLFP_00068 6.7e-23 ypbD S CAAX protease self-immunity
HFHCMLFP_00070 0.0 3.6.3.3, 3.6.3.5 P P-type ATPase
HFHCMLFP_00071 9.5e-33 copZ P Heavy-metal-associated domain
HFHCMLFP_00072 1.5e-98 dps P Belongs to the Dps family
HFHCMLFP_00073 4e-116 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HFHCMLFP_00074 9.7e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HFHCMLFP_00075 2.1e-227 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HFHCMLFP_00076 1.3e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HFHCMLFP_00077 1.5e-138 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HFHCMLFP_00078 1e-182 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HFHCMLFP_00079 3.6e-205
HFHCMLFP_00080 3.6e-308 norB EGP Major Facilitator
HFHCMLFP_00081 1.8e-107 K Bacterial regulatory proteins, tetR family
HFHCMLFP_00083 6.5e-128
HFHCMLFP_00084 1.4e-226 S ABC-type transport system involved in multi-copper enzyme maturation permease component
HFHCMLFP_00085 2.6e-166
HFHCMLFP_00086 1.1e-121 V ATPases associated with a variety of cellular activities
HFHCMLFP_00087 8.9e-65 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
HFHCMLFP_00088 1.7e-17
HFHCMLFP_00089 1.3e-176 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00090 4e-46 M Peptidoglycan-binding domain 1 protein
HFHCMLFP_00091 0.0 ybfG M peptidoglycan-binding domain-containing protein
HFHCMLFP_00093 4.6e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFHCMLFP_00094 5.2e-167 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFHCMLFP_00095 4.7e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFHCMLFP_00096 2.1e-70 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFHCMLFP_00097 1.1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFHCMLFP_00098 1.1e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
HFHCMLFP_00099 2.3e-187 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFHCMLFP_00100 3.7e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFHCMLFP_00101 5.6e-62
HFHCMLFP_00102 1.3e-72 3.6.1.55 L NUDIX domain
HFHCMLFP_00103 6.8e-148 EG EamA-like transporter family
HFHCMLFP_00104 2.3e-86 S Phospholipase A2
HFHCMLFP_00106 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HFHCMLFP_00107 9e-75 rplI J Binds to the 23S rRNA
HFHCMLFP_00108 1.8e-33 D nuclear chromosome segregation
HFHCMLFP_00109 2.4e-212 tagE3 2.4.1.52 GT4 M Glycosyltransferase, group 1 family protein
HFHCMLFP_00110 7.3e-193 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HFHCMLFP_00111 2.2e-48 prgA D nuclear chromosome segregation
HFHCMLFP_00115 7.9e-09
HFHCMLFP_00117 4.6e-247 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HFHCMLFP_00118 1.3e-218
HFHCMLFP_00120 2.4e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFHCMLFP_00121 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HFHCMLFP_00122 1.1e-56 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HFHCMLFP_00123 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HFHCMLFP_00124 7.9e-160 lysR5 K LysR substrate binding domain
HFHCMLFP_00125 2.1e-202 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_00126 1.1e-33 S Phospholipase_D-nuclease N-terminal
HFHCMLFP_00127 3.5e-166 yxlF V ABC transporter
HFHCMLFP_00128 2.7e-132 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HFHCMLFP_00129 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HFHCMLFP_00130 2.4e-124
HFHCMLFP_00131 6.8e-102 K Bacteriophage CI repressor helix-turn-helix domain
HFHCMLFP_00132 5.1e-259
HFHCMLFP_00133 2.6e-106 T Calcineurin-like phosphoesterase superfamily domain
HFHCMLFP_00134 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00135 6.9e-164 C COG0277 FAD FMN-containing dehydrogenases
HFHCMLFP_00136 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00137 2.8e-85 C COG0277 FAD FMN-containing dehydrogenases
HFHCMLFP_00139 3.2e-38
HFHCMLFP_00140 3.1e-41 S Protein of unknown function (DUF2089)
HFHCMLFP_00141 3.4e-180 I PAP2 superfamily
HFHCMLFP_00142 9.5e-208 mccF V LD-carboxypeptidase
HFHCMLFP_00143 4.3e-42
HFHCMLFP_00144 4e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HFHCMLFP_00145 3.1e-89 ogt 2.1.1.63 L Methyltransferase
HFHCMLFP_00146 2.8e-193 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFHCMLFP_00147 1.2e-43
HFHCMLFP_00148 2.8e-85 slyA K Transcriptional regulator
HFHCMLFP_00149 7.3e-164 1.6.5.5 C alcohol dehydrogenase
HFHCMLFP_00150 4.1e-54 ypaA S Protein of unknown function (DUF1304)
HFHCMLFP_00151 4.4e-53 S Protein of unknown function (DUF1516)
HFHCMLFP_00152 9.1e-254 pbuO S permease
HFHCMLFP_00153 6.3e-46 S DsrE/DsrF-like family
HFHCMLFP_00154 2.9e-179 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFHCMLFP_00155 4.9e-29
HFHCMLFP_00156 3.1e-104 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HFHCMLFP_00157 0.0
HFHCMLFP_00159 1.3e-121 S WxL domain surface cell wall-binding
HFHCMLFP_00160 1.5e-122 S WxL domain surface cell wall-binding
HFHCMLFP_00161 5.3e-182 ynjC S Cell surface protein
HFHCMLFP_00163 3.8e-268 L Mga helix-turn-helix domain
HFHCMLFP_00164 2.2e-174 yhaI S Protein of unknown function (DUF805)
HFHCMLFP_00165 1.2e-57
HFHCMLFP_00166 4.2e-253 rarA L recombination factor protein RarA
HFHCMLFP_00167 2.2e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFHCMLFP_00168 7.4e-160 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
HFHCMLFP_00169 1.2e-137 magIII L Base excision DNA repair protein, HhH-GPD family
HFHCMLFP_00170 8.3e-45 S Thiamine-binding protein
HFHCMLFP_00171 8.1e-229 yhgE V domain protein
HFHCMLFP_00172 3.3e-98 yobS K Bacterial regulatory proteins, tetR family
HFHCMLFP_00173 3.8e-252 bmr3 EGP Major facilitator Superfamily
HFHCMLFP_00175 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HFHCMLFP_00176 3.9e-298 oppA E ABC transporter, substratebinding protein
HFHCMLFP_00177 1.1e-19
HFHCMLFP_00178 6.6e-15
HFHCMLFP_00179 8.1e-79 S NUDIX domain
HFHCMLFP_00180 1.5e-211 S nuclear-transcribed mRNA catabolic process, no-go decay
HFHCMLFP_00181 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
HFHCMLFP_00182 2.2e-257 nox 1.6.3.4 C NADH oxidase
HFHCMLFP_00183 1.7e-116
HFHCMLFP_00184 5.2e-216 S TPM domain
HFHCMLFP_00185 4.6e-125 yxaA S Sulfite exporter TauE/SafE
HFHCMLFP_00186 1e-55 ywjH S Protein of unknown function (DUF1634)
HFHCMLFP_00188 6.5e-90
HFHCMLFP_00189 2.8e-48
HFHCMLFP_00190 2.4e-83 fld C Flavodoxin
HFHCMLFP_00191 1.2e-36
HFHCMLFP_00192 1.1e-26
HFHCMLFP_00193 9.2e-170 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFHCMLFP_00194 1.4e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
HFHCMLFP_00195 3.5e-39 S Transglycosylase associated protein
HFHCMLFP_00196 1.5e-81 S Protein conserved in bacteria
HFHCMLFP_00197 2.8e-25
HFHCMLFP_00198 7.4e-68 asp23 S Asp23 family, cell envelope-related function
HFHCMLFP_00199 1.6e-62 asp2 S Asp23 family, cell envelope-related function
HFHCMLFP_00200 1.1e-113 S Protein of unknown function (DUF969)
HFHCMLFP_00201 2.2e-152 S Protein of unknown function (DUF979)
HFHCMLFP_00202 1.4e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HFHCMLFP_00203 6.5e-108 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HFHCMLFP_00204 3e-127 cobQ S glutamine amidotransferase
HFHCMLFP_00205 1.3e-66
HFHCMLFP_00206 8.4e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HFHCMLFP_00207 1.7e-143 noc K Belongs to the ParB family
HFHCMLFP_00208 9.7e-138 soj D Sporulation initiation inhibitor
HFHCMLFP_00209 5.2e-156 spo0J K Belongs to the ParB family
HFHCMLFP_00210 1.8e-29 yyzM S Bacterial protein of unknown function (DUF951)
HFHCMLFP_00211 1.3e-185 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFHCMLFP_00212 2.1e-106 XK27_01040 S Protein of unknown function (DUF1129)
HFHCMLFP_00213 2.5e-275 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFHCMLFP_00214 1.6e-120
HFHCMLFP_00215 1.9e-121 K response regulator
HFHCMLFP_00216 3.9e-218 hpk31 2.7.13.3 T Histidine kinase
HFHCMLFP_00217 1.6e-236 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HFHCMLFP_00218 1.6e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFHCMLFP_00219 6.6e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFHCMLFP_00220 1.8e-141 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HFHCMLFP_00221 1e-164 yvgN C Aldo keto reductase
HFHCMLFP_00222 2.5e-123 gntR K rpiR family
HFHCMLFP_00223 2.5e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HFHCMLFP_00224 1.9e-305 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HFHCMLFP_00225 8.8e-211 gntP EG Gluconate
HFHCMLFP_00226 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00227 1.2e-204 S O-antigen ligase like membrane protein
HFHCMLFP_00228 7.2e-91 S Glycosyl transferase family 2
HFHCMLFP_00229 3.2e-95 welB S Glycosyltransferase like family 2
HFHCMLFP_00230 3e-118 rgpB GT2 M Glycosyl transferase family 2
HFHCMLFP_00231 7.2e-227 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HFHCMLFP_00232 8.4e-153 S Protein conserved in bacteria
HFHCMLFP_00233 7.6e-58
HFHCMLFP_00234 4.5e-129 fhuC 3.6.3.35 P ABC transporter
HFHCMLFP_00235 4e-134 znuB U ABC 3 transport family
HFHCMLFP_00236 4.2e-166 T Calcineurin-like phosphoesterase superfamily domain
HFHCMLFP_00237 3.2e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HFHCMLFP_00238 0.0 pepF E oligoendopeptidase F
HFHCMLFP_00239 7.4e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFHCMLFP_00240 2.9e-249 brnQ U Component of the transport system for branched-chain amino acids
HFHCMLFP_00241 7e-71 T Sh3 type 3 domain protein
HFHCMLFP_00242 1.1e-133 glcR K DeoR C terminal sensor domain
HFHCMLFP_00243 4.4e-146 M Glycosyltransferase like family 2
HFHCMLFP_00244 3.3e-135 XK27_06755 S Protein of unknown function (DUF975)
HFHCMLFP_00245 1.4e-40
HFHCMLFP_00246 1.1e-107 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HFHCMLFP_00247 6e-174 draG O ADP-ribosylglycohydrolase
HFHCMLFP_00248 4.3e-294 S ABC transporter
HFHCMLFP_00249 3.3e-135 Q Methyltransferase domain
HFHCMLFP_00250 6.1e-35
HFHCMLFP_00251 1.9e-68 S COG NOG38524 non supervised orthologous group
HFHCMLFP_00252 4e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
HFHCMLFP_00253 6.6e-11
HFHCMLFP_00254 2.1e-52 trxC O Belongs to the thioredoxin family
HFHCMLFP_00255 6.3e-137 thrE S Putative threonine/serine exporter
HFHCMLFP_00256 1.4e-75 S Threonine/Serine exporter, ThrE
HFHCMLFP_00257 5.8e-214 livJ E Receptor family ligand binding region
HFHCMLFP_00258 4.3e-150 livH U Branched-chain amino acid transport system / permease component
HFHCMLFP_00259 2.7e-121 livM E Branched-chain amino acid transport system / permease component
HFHCMLFP_00260 2.8e-140 livG E Branched-chain amino acid ATP-binding cassette transporter
HFHCMLFP_00261 5.1e-125 livF E ABC transporter
HFHCMLFP_00262 3.1e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HFHCMLFP_00263 1.9e-234 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCMLFP_00264 7.6e-118 XK27_12570 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HFHCMLFP_00265 2.8e-117 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HFHCMLFP_00266 1.3e-229 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HFHCMLFP_00267 3.4e-129 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HFHCMLFP_00268 1.6e-152 M NlpC P60 family protein
HFHCMLFP_00269 6.6e-237 L Transposase
HFHCMLFP_00272 2.7e-260 nox 1.6.3.4 C NADH oxidase
HFHCMLFP_00273 1.3e-159 sepS16B
HFHCMLFP_00274 2.3e-119
HFHCMLFP_00275 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HFHCMLFP_00276 1.7e-240 G Bacterial extracellular solute-binding protein
HFHCMLFP_00277 3.9e-85
HFHCMLFP_00278 0.0 strH 3.2.1.52 GH20 G Gram-positive signal peptide protein, YSIRK family
HFHCMLFP_00279 3.1e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
HFHCMLFP_00280 1.2e-129 XK27_08435 K UTRA
HFHCMLFP_00281 5.9e-219 agaS G SIS domain
HFHCMLFP_00282 2.2e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HFHCMLFP_00283 0.0 bgaC 3.2.1.23 G Glycosyl hydrolases family 35
HFHCMLFP_00284 3.6e-82 manX_1 2.7.1.191 G PTS system sorbose subfamily IIB component
HFHCMLFP_00285 2.3e-145 XK27_08455 G PTS system sorbose-specific iic component
HFHCMLFP_00286 6.8e-145 manZ_1 G PTS system mannose/fructose/sorbose family IID component
HFHCMLFP_00287 4.1e-58 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HFHCMLFP_00288 4.6e-82 tnp2PF3 L Transposase DDE domain
HFHCMLFP_00289 9.2e-65 XK27_08465 2.7.1.191 G PTS system fructose IIA component
HFHCMLFP_00290 1.1e-218 S Uncharacterized protein conserved in bacteria (DUF2325)
HFHCMLFP_00291 1.8e-191 4.4.1.8 E Aminotransferase, class I
HFHCMLFP_00292 4.4e-197 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HFHCMLFP_00293 8.6e-251 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCMLFP_00294 4e-59 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFHCMLFP_00295 2.5e-50 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HFHCMLFP_00296 2.1e-188 ypdE E M42 glutamyl aminopeptidase
HFHCMLFP_00297 0.0 licR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFHCMLFP_00298 9.5e-244 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HFHCMLFP_00299 7e-295 E ABC transporter, substratebinding protein
HFHCMLFP_00300 4e-121 S Acetyltransferase (GNAT) family
HFHCMLFP_00302 9.8e-95 S ABC-type cobalt transport system, permease component
HFHCMLFP_00303 1.1e-245 P ABC transporter
HFHCMLFP_00304 2.3e-108 P cobalt transport
HFHCMLFP_00305 2.6e-126 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HFHCMLFP_00306 1.3e-82 thiW S Thiamine-precursor transporter protein (ThiW)
HFHCMLFP_00307 2.1e-149 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFHCMLFP_00308 3.1e-105 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFHCMLFP_00309 2.5e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HFHCMLFP_00310 5.6e-272 E Amino acid permease
HFHCMLFP_00311 7.4e-31
HFHCMLFP_00312 3.5e-188 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HFHCMLFP_00313 8.6e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HFHCMLFP_00314 2e-283 rbsA 3.6.3.17 G ABC transporter
HFHCMLFP_00315 3.6e-145 rbsC U Belongs to the binding-protein-dependent transport system permease family
HFHCMLFP_00316 9.5e-167 rbsB G Periplasmic binding protein domain
HFHCMLFP_00317 3.1e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFHCMLFP_00318 1.4e-40 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HFHCMLFP_00319 0.0 pbpC M NTF2-like N-terminal transpeptidase domain
HFHCMLFP_00320 1.9e-237 ydiC1 EGP Major facilitator Superfamily
HFHCMLFP_00321 7.5e-71 K helix_turn_helix multiple antibiotic resistance protein
HFHCMLFP_00322 2e-100
HFHCMLFP_00323 1.8e-17
HFHCMLFP_00324 1.2e-62
HFHCMLFP_00325 2.1e-46
HFHCMLFP_00326 2.3e-268 frdC 1.3.5.4 C HI0933-like protein
HFHCMLFP_00327 3.5e-198 GKT transcriptional antiterminator
HFHCMLFP_00328 1.5e-49 ptxB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HFHCMLFP_00329 2.7e-209 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HFHCMLFP_00330 2.6e-68
HFHCMLFP_00331 7.5e-163 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HFHCMLFP_00332 7.4e-115 6.3.4.4 S Zeta toxin
HFHCMLFP_00333 1.2e-157 K Sugar-specific transcriptional regulator TrmB
HFHCMLFP_00334 3.4e-147 S Sulfite exporter TauE/SafE
HFHCMLFP_00335 8.6e-179 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
HFHCMLFP_00336 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00337 3.1e-124 3.1.1.24 S Alpha/beta hydrolase family
HFHCMLFP_00340 1.6e-141 M Bacterial Ig-like domain (group 3)
HFHCMLFP_00341 1.7e-69 pdxH S Pyridoxamine 5'-phosphate oxidase
HFHCMLFP_00342 1.1e-70 yqeB S Pyrimidine dimer DNA glycosylase
HFHCMLFP_00343 8.4e-152 3.5.2.6 V Beta-lactamase
HFHCMLFP_00344 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00345 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00346 2e-40 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HFHCMLFP_00347 2.1e-74 2.7.1.191 G PTS system sorbose subfamily IIB component
HFHCMLFP_00348 2.5e-58 2.7.1.191 G PTS system fructose IIA component
HFHCMLFP_00349 3e-293 G PTS system sorbose-specific iic component
HFHCMLFP_00350 1e-109 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
HFHCMLFP_00351 4.5e-138 K helix_turn _helix lactose operon repressor
HFHCMLFP_00352 1.1e-218 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HFHCMLFP_00353 3.1e-206 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HFHCMLFP_00354 1.1e-35 glvR K Helix-turn-helix domain, rpiR family
HFHCMLFP_00355 1.1e-09
HFHCMLFP_00356 3.5e-20 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HFHCMLFP_00357 1.1e-46 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HFHCMLFP_00358 7.9e-51 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HFHCMLFP_00359 2.3e-162 P YhfZ C-terminal domain
HFHCMLFP_00360 5.6e-08
HFHCMLFP_00361 1.3e-55 yhfU S Protein of unknown function DUF2620
HFHCMLFP_00362 4e-192 yhfT S Protein of unknown function
HFHCMLFP_00363 4.1e-156 php S Phosphotriesterase family
HFHCMLFP_00364 8.3e-183 bioF 2.3.1.47, 2.8.1.6 E Cys/Met metabolism PLP-dependent enzyme
HFHCMLFP_00365 1.2e-200 yhfX E Alanine racemase, N-terminal domain
HFHCMLFP_00366 6.3e-232 yhfW G Metalloenzyme superfamily
HFHCMLFP_00367 0.0 ebgA 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HFHCMLFP_00368 4.9e-271 ygjI E Amino Acid
HFHCMLFP_00369 2.8e-239 lysP E amino acid
HFHCMLFP_00370 5.1e-143 K helix_turn_helix, arabinose operon control protein
HFHCMLFP_00371 9e-50
HFHCMLFP_00373 0.0 K Sigma-54 interaction domain
HFHCMLFP_00374 2.4e-72 levA G PTS system fructose IIA component
HFHCMLFP_00375 4.8e-90 2.7.1.191 G PTS system sorbose subfamily IIB component
HFHCMLFP_00376 4.1e-153 M PTS system sorbose-specific iic component
HFHCMLFP_00377 1.9e-147 levD G PTS system mannose/fructose/sorbose family IID component
HFHCMLFP_00378 1.2e-55
HFHCMLFP_00379 2.2e-270 G Glycosyl hydrolases family 32
HFHCMLFP_00381 1.4e-121 S Haloacid dehalogenase-like hydrolase
HFHCMLFP_00382 3.8e-134 fruR K DeoR C terminal sensor domain
HFHCMLFP_00383 2.6e-112 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HFHCMLFP_00384 1.8e-96 hxlB 4.1.2.43, 5.3.1.27 M SIS domain
HFHCMLFP_00385 0.0 mtlF 2.7.1.197 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFHCMLFP_00386 9.8e-222 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HFHCMLFP_00387 4.6e-191 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
HFHCMLFP_00388 6.6e-131 E ABC transporter
HFHCMLFP_00389 1.8e-159 ET Bacterial periplasmic substrate-binding proteins
HFHCMLFP_00390 2.9e-114 P Binding-protein-dependent transport system inner membrane component
HFHCMLFP_00391 4.6e-115 P Binding-protein-dependent transport system inner membrane component
HFHCMLFP_00392 2.3e-237 kgtP EGP Sugar (and other) transporter
HFHCMLFP_00394 8.1e-12 S YvrJ protein family
HFHCMLFP_00395 6.4e-142 3.2.1.17 M hydrolase, family 25
HFHCMLFP_00396 6.5e-131 VY92_08700 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HFHCMLFP_00397 3.6e-114 C Flavodoxin
HFHCMLFP_00398 8.7e-87 ygfC K Bacterial regulatory proteins, tetR family
HFHCMLFP_00399 1.7e-185 hrtB V ABC transporter permease
HFHCMLFP_00400 2.4e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HFHCMLFP_00401 1.2e-39 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_00402 4.4e-64 S Phage derived protein Gp49-like (DUF891)
HFHCMLFP_00403 2.9e-262 npr 1.11.1.1 C NADH oxidase
HFHCMLFP_00404 6.3e-151 S hydrolase
HFHCMLFP_00405 1.9e-43 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HFHCMLFP_00406 6.2e-185 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HFHCMLFP_00407 3e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
HFHCMLFP_00408 2.8e-127 G PTS system sorbose-specific iic component
HFHCMLFP_00409 8.2e-154 G PTS system mannose/fructose/sorbose family IID component
HFHCMLFP_00410 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HFHCMLFP_00411 6.8e-69 2.7.1.191 G PTS system fructose IIA component
HFHCMLFP_00412 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HFHCMLFP_00413 1.8e-310 md2 V ABC transporter
HFHCMLFP_00414 5.1e-304 yfiB V ABC transporter transmembrane region
HFHCMLFP_00416 0.0 pip V domain protein
HFHCMLFP_00417 1.5e-155 metQ_4 P Belongs to the nlpA lipoprotein family
HFHCMLFP_00418 1.1e-197 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HFHCMLFP_00419 3e-83
HFHCMLFP_00420 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HFHCMLFP_00421 1.7e-15
HFHCMLFP_00422 1.5e-100 K Bacterial regulatory proteins, tetR family
HFHCMLFP_00423 7.3e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
HFHCMLFP_00424 1.3e-102 dhaL 2.7.1.121 S Dak2
HFHCMLFP_00425 1.4e-189 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HFHCMLFP_00426 1e-75 ohr O OsmC-like protein
HFHCMLFP_00427 3.1e-270 L Exonuclease
HFHCMLFP_00428 1.4e-47 K Helix-turn-helix domain
HFHCMLFP_00429 4.5e-203 yceJ EGP Major facilitator Superfamily
HFHCMLFP_00430 1.3e-18 K transcriptional regulator
HFHCMLFP_00431 5.2e-35
HFHCMLFP_00432 4.9e-102 tag 3.2.2.20 L glycosylase
HFHCMLFP_00433 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HFHCMLFP_00434 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HFHCMLFP_00435 1.8e-195 V Beta-lactamase
HFHCMLFP_00436 3.1e-150 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HFHCMLFP_00437 2.8e-142 H Protein of unknown function (DUF1698)
HFHCMLFP_00438 5.7e-143 puuD S peptidase C26
HFHCMLFP_00439 8.1e-257 6.3.1.2 E Glutamine synthetase, catalytic domain
HFHCMLFP_00440 7.1e-222 S Amidohydrolase
HFHCMLFP_00441 1.3e-238 E Amino acid permease
HFHCMLFP_00442 6.5e-75 K helix_turn_helix, mercury resistance
HFHCMLFP_00443 1.5e-163 morA2 S reductase
HFHCMLFP_00444 6.9e-200 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HFHCMLFP_00445 6.4e-57 hxlR K Transcriptional regulator, HxlR family
HFHCMLFP_00446 8.5e-97
HFHCMLFP_00447 4.8e-292 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCMLFP_00448 4.4e-56 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HFHCMLFP_00449 4.3e-228 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCMLFP_00450 1.5e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFHCMLFP_00451 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
HFHCMLFP_00452 4.5e-103 L Resolvase, N terminal domain
HFHCMLFP_00453 0.0 yvcC M Cna protein B-type domain
HFHCMLFP_00454 8.8e-125 M domain protein
HFHCMLFP_00455 1.4e-184 M LPXTG cell wall anchor motif
HFHCMLFP_00456 1.9e-27 3.4.22.70 M Sortase family
HFHCMLFP_00457 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00458 8.1e-154 3.4.22.70 M Sortase family
HFHCMLFP_00459 1.3e-126 XK27_12140 V ATPases associated with a variety of cellular activities
HFHCMLFP_00460 3.3e-297 S Psort location CytoplasmicMembrane, score
HFHCMLFP_00461 2.7e-126 K Transcriptional regulatory protein, C terminal
HFHCMLFP_00462 2.3e-196 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HFHCMLFP_00463 7e-140 V ATPases associated with a variety of cellular activities
HFHCMLFP_00464 2.7e-208
HFHCMLFP_00465 8.6e-92
HFHCMLFP_00466 0.0 O Belongs to the peptidase S8 family
HFHCMLFP_00467 0.0 O Belongs to the peptidase S8 family
HFHCMLFP_00468 0.0 pepN 3.4.11.2 E aminopeptidase
HFHCMLFP_00469 7.8e-274 ycaM E amino acid
HFHCMLFP_00470 1.3e-77 S Protein of unknown function (DUF1440)
HFHCMLFP_00471 1.1e-164 K Transcriptional regulator, LysR family
HFHCMLFP_00472 1.2e-160 G Xylose isomerase-like TIM barrel
HFHCMLFP_00473 1.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
HFHCMLFP_00474 1e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFHCMLFP_00475 1.2e-211 ydiN EGP Major Facilitator Superfamily
HFHCMLFP_00476 1.2e-168 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFHCMLFP_00477 8.1e-159 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HFHCMLFP_00478 4.6e-174 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HFHCMLFP_00479 9.1e-34
HFHCMLFP_00480 7.3e-35 lytN 3.5.1.104 M LysM domain
HFHCMLFP_00481 1.3e-18 S peptidase inhibitor activity
HFHCMLFP_00484 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00485 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00486 1.2e-43 lytN 3.5.1.104 M LysM domain
HFHCMLFP_00487 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00488 5.4e-33 S peptidase inhibitor activity
HFHCMLFP_00489 7.2e-48
HFHCMLFP_00490 6.7e-07 K sequence-specific DNA binding
HFHCMLFP_00491 8.7e-10 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_00492 6e-19 K sequence-specific DNA binding
HFHCMLFP_00493 1.9e-14 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_00494 2.1e-55
HFHCMLFP_00497 4.2e-144
HFHCMLFP_00498 2.1e-213 metC 4.4.1.8 E cystathionine
HFHCMLFP_00499 1.1e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HFHCMLFP_00500 5.3e-122 tcyB E ABC transporter
HFHCMLFP_00501 1.4e-31
HFHCMLFP_00502 1.6e-252 brnQ U Component of the transport system for branched-chain amino acids
HFHCMLFP_00503 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00504 7.4e-118 S WxL domain surface cell wall-binding
HFHCMLFP_00505 3.2e-173 S Cell surface protein
HFHCMLFP_00506 3.6e-29
HFHCMLFP_00507 5.9e-124 XK27_00720 S Leucine-rich repeat (LRR) protein
HFHCMLFP_00508 5.4e-58 XK27_00720 S Leucine-rich repeat (LRR) protein
HFHCMLFP_00509 4.9e-50 S WxL domain surface cell wall-binding
HFHCMLFP_00510 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_00511 1.1e-47 S WxL domain surface cell wall-binding
HFHCMLFP_00512 6.7e-57
HFHCMLFP_00513 8.3e-104 N WxL domain surface cell wall-binding
HFHCMLFP_00514 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HFHCMLFP_00515 4.6e-177 yicL EG EamA-like transporter family
HFHCMLFP_00516 0.0
HFHCMLFP_00517 2.2e-145 CcmA5 V ABC transporter
HFHCMLFP_00518 1.3e-88 S ECF-type riboflavin transporter, S component
HFHCMLFP_00519 3.8e-148 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HFHCMLFP_00520 1.6e-165 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
HFHCMLFP_00521 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HFHCMLFP_00523 0.0 XK27_09600 V ABC transporter, ATP-binding protein
HFHCMLFP_00524 0.0 V ABC transporter
HFHCMLFP_00525 4.2e-223 oxlT P Major Facilitator Superfamily
HFHCMLFP_00526 7.7e-129 treR K UTRA
HFHCMLFP_00527 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HFHCMLFP_00528 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFHCMLFP_00529 1.5e-215 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HFHCMLFP_00530 1.9e-267 yfnA E Amino Acid
HFHCMLFP_00531 3e-173 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HFHCMLFP_00532 7.1e-253 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HFHCMLFP_00533 4.6e-31 K 'Cold-shock' DNA-binding domain
HFHCMLFP_00534 1.9e-69
HFHCMLFP_00535 1.6e-76 O OsmC-like protein
HFHCMLFP_00536 3e-276 lsa S ABC transporter
HFHCMLFP_00537 6.1e-114 ylbE GM NAD(P)H-binding
HFHCMLFP_00538 7e-07 yeaE S Aldo/keto reductase family
HFHCMLFP_00539 1.9e-158 yeaE S Aldo/keto reductase family
HFHCMLFP_00540 5.7e-250 yifK E Amino acid permease
HFHCMLFP_00541 6.5e-259 S Protein of unknown function (DUF3800)
HFHCMLFP_00542 0.0 yjcE P Sodium proton antiporter
HFHCMLFP_00543 1.5e-44 S Protein of unknown function (DUF3021)
HFHCMLFP_00544 1.7e-73 K LytTr DNA-binding domain
HFHCMLFP_00545 1.6e-149 cylB V ABC-2 type transporter
HFHCMLFP_00546 7e-164 cylA V ABC transporter
HFHCMLFP_00547 1.8e-144 S Alpha/beta hydrolase of unknown function (DUF915)
HFHCMLFP_00548 1.4e-121 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HFHCMLFP_00549 2.6e-52 ybjQ S Belongs to the UPF0145 family
HFHCMLFP_00550 2.1e-160 3.5.1.10 C nadph quinone reductase
HFHCMLFP_00551 1.3e-246 amt P ammonium transporter
HFHCMLFP_00552 2.4e-178 yfeX P Peroxidase
HFHCMLFP_00553 2e-118 yhiD S MgtC family
HFHCMLFP_00554 6.9e-118 F DNA RNA non-specific endonuclease
HFHCMLFP_00556 2.1e-114 L COG3666 Transposase and inactivated derivatives
HFHCMLFP_00559 1.7e-40 gluP 3.4.21.105 S proteolysis
HFHCMLFP_00560 7.9e-123 gluP 3.4.21.105 S proteolysis
HFHCMLFP_00561 0.0 ybiT S ABC transporter, ATP-binding protein
HFHCMLFP_00562 0.0 mutS L ATPase domain of DNA mismatch repair MUTS family
HFHCMLFP_00563 4.9e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
HFHCMLFP_00564 2.4e-130 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HFHCMLFP_00565 1.2e-303 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HFHCMLFP_00566 5e-295 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFHCMLFP_00567 7.2e-135 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
HFHCMLFP_00568 1.1e-153 lacT K PRD domain
HFHCMLFP_00569 4e-309 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HFHCMLFP_00570 1.3e-273 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HFHCMLFP_00571 1.9e-50 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HFHCMLFP_00572 3.3e-222 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFHCMLFP_00573 3.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HFHCMLFP_00574 4.3e-280 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HFHCMLFP_00575 5.4e-165 K Transcriptional regulator
HFHCMLFP_00576 7.6e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HFHCMLFP_00578 1.6e-85 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFHCMLFP_00579 1.4e-50 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HFHCMLFP_00580 7.2e-267 gatC G PTS system sugar-specific permease component
HFHCMLFP_00581 2.1e-25
HFHCMLFP_00582 5.2e-127 S Domain of unknown function (DUF4867)
HFHCMLFP_00583 3.8e-176 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HFHCMLFP_00584 8.6e-187 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HFHCMLFP_00585 3.8e-93 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HFHCMLFP_00586 7.9e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
HFHCMLFP_00587 4.2e-141 lacR K DeoR C terminal sensor domain
HFHCMLFP_00588 3.8e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HFHCMLFP_00589 5.1e-212 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HFHCMLFP_00590 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HFHCMLFP_00591 2.1e-14
HFHCMLFP_00593 2.2e-76 hsp1 O Belongs to the small heat shock protein (HSP20) family
HFHCMLFP_00595 9.3e-212 mutY L A G-specific adenine glycosylase
HFHCMLFP_00596 1.1e-107 cytC6 I alpha/beta hydrolase fold
HFHCMLFP_00597 4.6e-28 cytC6 I alpha/beta hydrolase fold
HFHCMLFP_00598 9.4e-121 yrkL S Flavodoxin-like fold
HFHCMLFP_00600 2e-86 S Short repeat of unknown function (DUF308)
HFHCMLFP_00601 4.1e-118 S Psort location Cytoplasmic, score
HFHCMLFP_00602 4.6e-154 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HFHCMLFP_00603 8.2e-196
HFHCMLFP_00604 3.9e-07
HFHCMLFP_00605 1.5e-115 ywnB S NAD(P)H-binding
HFHCMLFP_00606 0.0 bglB 3.2.1.21 GH3 G hydrolase, family 3
HFHCMLFP_00607 1.8e-165 XK27_00670 S ABC transporter substrate binding protein
HFHCMLFP_00608 2.2e-163 XK27_00670 S ABC transporter
HFHCMLFP_00609 6.5e-155 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HFHCMLFP_00610 8.8e-142 cmpC S ABC transporter, ATP-binding protein
HFHCMLFP_00611 1e-173 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
HFHCMLFP_00612 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HFHCMLFP_00613 6.2e-182 ykcC GT2 M Glycosyl transferase family 2
HFHCMLFP_00614 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
HFHCMLFP_00615 4.1e-71 S GtrA-like protein
HFHCMLFP_00616 5.3e-124 K cheY-homologous receiver domain
HFHCMLFP_00617 2.4e-242 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HFHCMLFP_00618 3.1e-68 yqkB S Belongs to the HesB IscA family
HFHCMLFP_00619 5.5e-220 QT PucR C-terminal helix-turn-helix domain
HFHCMLFP_00620 2.5e-43 L 4.5 Transposon and IS
HFHCMLFP_00621 6.1e-154 L 4.5 Transposon and IS
HFHCMLFP_00622 2.9e-16 QT PucR C-terminal helix-turn-helix domain
HFHCMLFP_00623 2.8e-162 ptlF S KR domain
HFHCMLFP_00624 1.4e-158 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HFHCMLFP_00625 1.3e-122 drgA C Nitroreductase family
HFHCMLFP_00626 2e-205 lctO C IMP dehydrogenase / GMP reductase domain
HFHCMLFP_00629 6.6e-190 K DNA-binding helix-turn-helix protein
HFHCMLFP_00630 1.5e-58 K Transcriptional regulator PadR-like family
HFHCMLFP_00631 1.2e-41 ygbF S Sugar efflux transporter for intercellular exchange
HFHCMLFP_00632 8.7e-42
HFHCMLFP_00633 4.5e-191 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HFHCMLFP_00635 3.1e-54
HFHCMLFP_00636 1.5e-80
HFHCMLFP_00637 3.2e-209 yubA S AI-2E family transporter
HFHCMLFP_00638 3.1e-24
HFHCMLFP_00639 1.5e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFHCMLFP_00640 2.7e-45
HFHCMLFP_00641 1e-165 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HFHCMLFP_00642 2.5e-88 ywrF S Flavin reductase like domain
HFHCMLFP_00643 4.9e-72
HFHCMLFP_00644 3e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFHCMLFP_00645 5.7e-61 yeaO S Protein of unknown function, DUF488
HFHCMLFP_00646 1.3e-173 corA P CorA-like Mg2+ transporter protein
HFHCMLFP_00647 1.3e-157 mleR K LysR family
HFHCMLFP_00648 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HFHCMLFP_00649 3.2e-170 mleP S Sodium Bile acid symporter family
HFHCMLFP_00650 1.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HFHCMLFP_00651 9.4e-86 C FMN binding
HFHCMLFP_00652 0.0 pepF E Oligopeptidase F
HFHCMLFP_00653 2.4e-59
HFHCMLFP_00654 5.8e-132 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HFHCMLFP_00655 1.7e-81 ndk 2.7.4.6 F Belongs to the NDK family
HFHCMLFP_00656 0.0 yfgQ P E1-E2 ATPase
HFHCMLFP_00657 1.9e-180 3.4.11.5 I carboxylic ester hydrolase activity
HFHCMLFP_00658 2.6e-45
HFHCMLFP_00659 2.6e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HFHCMLFP_00660 3.6e-197 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HFHCMLFP_00661 2.2e-122 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
HFHCMLFP_00662 8.8e-78 K Transcriptional regulator
HFHCMLFP_00663 9.5e-180 D Alpha beta
HFHCMLFP_00664 1.1e-83 nrdI F Belongs to the NrdI family
HFHCMLFP_00665 1.3e-156 dkgB S reductase
HFHCMLFP_00666 1e-155
HFHCMLFP_00667 2.2e-143 S Alpha beta hydrolase
HFHCMLFP_00668 6.6e-119 yviA S Protein of unknown function (DUF421)
HFHCMLFP_00669 3.5e-74 S Protein of unknown function (DUF3290)
HFHCMLFP_00671 1.6e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HFHCMLFP_00672 2.2e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFHCMLFP_00673 1.4e-104 yjbF S SNARE associated Golgi protein
HFHCMLFP_00674 6e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFHCMLFP_00675 5.5e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFHCMLFP_00676 1e-206 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HFHCMLFP_00677 3.9e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFHCMLFP_00678 2.4e-66 yajC U Preprotein translocase
HFHCMLFP_00679 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HFHCMLFP_00680 2.3e-116 sirR K Helix-turn-helix diphteria tox regulatory element
HFHCMLFP_00681 2.5e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFHCMLFP_00682 9.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFHCMLFP_00683 2.3e-240 ytoI K DRTGG domain
HFHCMLFP_00684 3.1e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HFHCMLFP_00685 1.1e-250 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFHCMLFP_00686 2.1e-174
HFHCMLFP_00687 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFHCMLFP_00689 4e-43 yrzL S Belongs to the UPF0297 family
HFHCMLFP_00690 1.6e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFHCMLFP_00691 6.8e-53 yrzB S Belongs to the UPF0473 family
HFHCMLFP_00692 5.8e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HFHCMLFP_00693 4.7e-91 cvpA S Colicin V production protein
HFHCMLFP_00694 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFHCMLFP_00695 6.6e-53 trxA O Belongs to the thioredoxin family
HFHCMLFP_00696 6.1e-20 dltX S D-Ala-teichoic acid biosynthesis protein
HFHCMLFP_00697 7.2e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFHCMLFP_00698 2.6e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
HFHCMLFP_00699 1.2e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFHCMLFP_00700 3.3e-244 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFHCMLFP_00701 3.6e-85 yslB S Protein of unknown function (DUF2507)
HFHCMLFP_00702 5e-276 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HFHCMLFP_00703 1.6e-96 S Phosphoesterase
HFHCMLFP_00704 2.5e-135 gla U Major intrinsic protein
HFHCMLFP_00705 2.1e-85 ykuL S CBS domain
HFHCMLFP_00706 1.3e-157 XK27_00890 S Domain of unknown function (DUF368)
HFHCMLFP_00707 3.2e-153 ykuT M mechanosensitive ion channel
HFHCMLFP_00708 6e-12 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFHCMLFP_00709 1.2e-86 ytxH S YtxH-like protein
HFHCMLFP_00710 1.8e-90 niaR S 3H domain
HFHCMLFP_00711 2.8e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HFHCMLFP_00712 6e-180 ccpA K catabolite control protein A
HFHCMLFP_00713 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
HFHCMLFP_00714 4e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
HFHCMLFP_00715 9.5e-138 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFHCMLFP_00716 1.1e-272 pepV 3.5.1.18 E dipeptidase PepV
HFHCMLFP_00717 7.3e-258 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HFHCMLFP_00718 2.7e-54
HFHCMLFP_00719 7.5e-189 yibE S overlaps another CDS with the same product name
HFHCMLFP_00720 1.4e-114 yibF S overlaps another CDS with the same product name
HFHCMLFP_00721 6.3e-116 S Calcineurin-like phosphoesterase
HFHCMLFP_00722 2.2e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HFHCMLFP_00723 5.1e-116 yutD S Protein of unknown function (DUF1027)
HFHCMLFP_00724 2.8e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFHCMLFP_00725 1.1e-112 S Protein of unknown function (DUF1461)
HFHCMLFP_00726 5.2e-116 dedA S SNARE-like domain protein
HFHCMLFP_00727 6.7e-87 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HFHCMLFP_00728 5.1e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HFHCMLFP_00729 2.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFHCMLFP_00730 1.1e-62 yugI 5.3.1.9 J general stress protein
HFHCMLFP_00731 6.1e-35
HFHCMLFP_00732 1.9e-68 S COG NOG38524 non supervised orthologous group
HFHCMLFP_00733 4e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
HFHCMLFP_00759 2.1e-94 sigH K DNA-templated transcription, initiation
HFHCMLFP_00760 1e-283 ybeC E amino acid
HFHCMLFP_00761 5.8e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HFHCMLFP_00762 5e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
HFHCMLFP_00763 1.9e-165 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFHCMLFP_00765 2.1e-216 patA 2.6.1.1 E Aminotransferase
HFHCMLFP_00766 1.9e-43 ykuJ S Protein of unknown function (DUF1797)
HFHCMLFP_00767 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFHCMLFP_00768 4e-80 perR P Belongs to the Fur family
HFHCMLFP_00769 6.1e-35
HFHCMLFP_00770 1.9e-68 S COG NOG38524 non supervised orthologous group
HFHCMLFP_00771 4e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
HFHCMLFP_00775 4.3e-70
HFHCMLFP_00776 1.1e-209 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFHCMLFP_00777 4e-265 emrY EGP Major facilitator Superfamily
HFHCMLFP_00778 6.7e-81 merR K MerR HTH family regulatory protein
HFHCMLFP_00779 8.1e-266 lmrB EGP Major facilitator Superfamily
HFHCMLFP_00780 4.1e-106 S Domain of unknown function (DUF4811)
HFHCMLFP_00781 2.4e-119 3.6.1.27 I Acid phosphatase homologues
HFHCMLFP_00782 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFHCMLFP_00783 2.2e-280 ytgP S Polysaccharide biosynthesis protein
HFHCMLFP_00784 7.6e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFHCMLFP_00785 1.4e-33 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HFHCMLFP_00786 4.8e-143 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFHCMLFP_00787 1.3e-93 FNV0100 F NUDIX domain
HFHCMLFP_00789 1.2e-216 L Belongs to the 'phage' integrase family
HFHCMLFP_00791 7.2e-25
HFHCMLFP_00792 2.2e-73 kch J Ion transport protein
HFHCMLFP_00793 5e-16 E Zn peptidase
HFHCMLFP_00794 3.1e-16 ps115 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_00796 5.2e-125 K Phage regulatory protein
HFHCMLFP_00798 1.1e-38 S Domain of unknown function (DUF771)
HFHCMLFP_00801 2.3e-167 yqaJ L YqaJ-like viral recombinase domain
HFHCMLFP_00803 4.2e-161 recT L RecT family
HFHCMLFP_00804 3.8e-35 K Transcriptional regulator
HFHCMLFP_00805 6.2e-122 L Transcriptional regulator
HFHCMLFP_00806 6.7e-153 dnaC L IstB-like ATP binding protein
HFHCMLFP_00808 3.7e-42
HFHCMLFP_00810 1.3e-102 S HNH endonuclease
HFHCMLFP_00811 1.2e-73 rusA L Endodeoxyribonuclease RusA
HFHCMLFP_00812 6e-39
HFHCMLFP_00814 9.2e-80
HFHCMLFP_00816 1.2e-08
HFHCMLFP_00817 1.8e-68 V HNH endonuclease
HFHCMLFP_00818 1.1e-59
HFHCMLFP_00819 0.0 S overlaps another CDS with the same product name
HFHCMLFP_00820 2.4e-231 S Phage portal protein
HFHCMLFP_00821 1e-125 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HFHCMLFP_00822 6.4e-216 S Phage capsid family
HFHCMLFP_00824 3.1e-53
HFHCMLFP_00825 9.7e-58 S Phage head-tail joining protein
HFHCMLFP_00826 1.8e-56
HFHCMLFP_00827 2.2e-66
HFHCMLFP_00828 9.1e-113
HFHCMLFP_00829 2e-61
HFHCMLFP_00830 0.0 D Phage tail tape measure protein
HFHCMLFP_00831 2.9e-125 S phage tail
HFHCMLFP_00832 0.0 tcdA2 GT2,GT4 LM gp58-like protein
HFHCMLFP_00833 3.9e-72
HFHCMLFP_00834 8.1e-39
HFHCMLFP_00835 7.1e-43
HFHCMLFP_00836 5.6e-50 hol S Bacteriophage holin
HFHCMLFP_00838 1.2e-196 M Bacteriophage peptidoglycan hydrolase
HFHCMLFP_00839 3.4e-288 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
HFHCMLFP_00840 1.4e-305 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HFHCMLFP_00841 2.4e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HFHCMLFP_00843 3.9e-234 malY 4.4.1.8 E Aminotransferase, class I
HFHCMLFP_00844 2.9e-259 cpdA S Calcineurin-like phosphoesterase
HFHCMLFP_00845 1e-38 gcvR T Belongs to the UPF0237 family
HFHCMLFP_00846 1.2e-244 XK27_08635 S UPF0210 protein
HFHCMLFP_00847 1.9e-213 coiA 3.6.4.12 S Competence protein
HFHCMLFP_00848 1.1e-113 yjbH Q Thioredoxin
HFHCMLFP_00849 7.5e-106 yjbK S CYTH
HFHCMLFP_00850 1.3e-122 yjbM 2.7.6.5 S RelA SpoT domain protein
HFHCMLFP_00851 4.6e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFHCMLFP_00852 5.1e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HFHCMLFP_00853 1.5e-202 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFHCMLFP_00854 7.5e-112 cutC P Participates in the control of copper homeostasis
HFHCMLFP_00855 2.1e-143 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HFHCMLFP_00856 3.5e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HFHCMLFP_00857 2.5e-62 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HFHCMLFP_00858 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFHCMLFP_00859 1.7e-190 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFHCMLFP_00860 5.7e-172 corA P CorA-like Mg2+ transporter protein
HFHCMLFP_00861 1.1e-155 rrmA 2.1.1.187 H Methyltransferase
HFHCMLFP_00862 9.4e-97 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFHCMLFP_00863 8.4e-72 WQ51_03320 S Protein of unknown function (DUF1149)
HFHCMLFP_00864 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HFHCMLFP_00865 4.7e-230 ymfF S Peptidase M16 inactive domain protein
HFHCMLFP_00866 8.4e-243 ymfH S Peptidase M16
HFHCMLFP_00867 6e-129 IQ Enoyl-(Acyl carrier protein) reductase
HFHCMLFP_00868 1.3e-109 ymfM S Helix-turn-helix domain
HFHCMLFP_00869 1.9e-104 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFHCMLFP_00870 8.6e-229 cinA 3.5.1.42 S Belongs to the CinA family
HFHCMLFP_00871 3e-190 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFHCMLFP_00872 3.1e-231 rny S Endoribonuclease that initiates mRNA decay
HFHCMLFP_00873 5.2e-116 yvyE 3.4.13.9 S YigZ family
HFHCMLFP_00874 9.7e-236 comFA L Helicase C-terminal domain protein
HFHCMLFP_00875 6.6e-82 comFC S Competence protein
HFHCMLFP_00876 2.1e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFHCMLFP_00877 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFHCMLFP_00878 3.9e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFHCMLFP_00879 5.4e-124 ftsE D ABC transporter
HFHCMLFP_00881 8e-202 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HFHCMLFP_00882 2.4e-130 K response regulator
HFHCMLFP_00883 1.1e-308 phoR 2.7.13.3 T Histidine kinase
HFHCMLFP_00884 1.2e-152 pstS P Phosphate
HFHCMLFP_00885 3.6e-155 pstC P probably responsible for the translocation of the substrate across the membrane
HFHCMLFP_00886 1.8e-156 pstA P Phosphate transport system permease protein PstA
HFHCMLFP_00887 3.1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFHCMLFP_00888 1.6e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFHCMLFP_00889 1e-119 phoU P Plays a role in the regulation of phosphate uptake
HFHCMLFP_00890 2.4e-262 yvlB S Putative adhesin
HFHCMLFP_00891 1.4e-30
HFHCMLFP_00892 4.4e-34 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HFHCMLFP_00893 2.1e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFHCMLFP_00894 2e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFHCMLFP_00895 2e-194 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HFHCMLFP_00896 2.4e-178 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFHCMLFP_00897 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HFHCMLFP_00898 1.4e-113 T Transcriptional regulatory protein, C terminal
HFHCMLFP_00899 8.4e-174 T His Kinase A (phosphoacceptor) domain
HFHCMLFP_00900 2.6e-91 V ABC transporter
HFHCMLFP_00901 0.0 V FtsX-like permease family
HFHCMLFP_00902 9.4e-118 yfbR S HD containing hydrolase-like enzyme
HFHCMLFP_00903 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFHCMLFP_00904 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFHCMLFP_00905 1.8e-85 S Short repeat of unknown function (DUF308)
HFHCMLFP_00906 9.7e-166 rapZ S Displays ATPase and GTPase activities
HFHCMLFP_00907 2.4e-192 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HFHCMLFP_00908 8.2e-171 whiA K May be required for sporulation
HFHCMLFP_00909 8.4e-81 ohrR K helix_turn_helix multiple antibiotic resistance protein
HFHCMLFP_00910 1.9e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFHCMLFP_00912 6.6e-215 L Belongs to the 'phage' integrase family
HFHCMLFP_00915 6.3e-22 E Zn peptidase
HFHCMLFP_00916 1.9e-48 ps115 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_00918 1.2e-10
HFHCMLFP_00921 2.9e-38 F nucleoside 2-deoxyribosyltransferase
HFHCMLFP_00923 1.5e-22
HFHCMLFP_00926 1.6e-57 S Domain of unknown function (DUF771)
HFHCMLFP_00929 8.9e-22
HFHCMLFP_00932 2.8e-82 S Siphovirus Gp157
HFHCMLFP_00933 2.2e-257 res L Helicase C-terminal domain protein
HFHCMLFP_00934 4.6e-129 L AAA domain
HFHCMLFP_00935 1.2e-91
HFHCMLFP_00936 1.5e-149 L Bifunctional DNA primase/polymerase, N-terminal
HFHCMLFP_00937 6.4e-224 S Virulence-associated protein E
HFHCMLFP_00938 3.9e-53 S VRR_NUC
HFHCMLFP_00939 3.7e-42
HFHCMLFP_00941 2.4e-104 S HNH endonuclease
HFHCMLFP_00943 9.2e-71 S Transcriptional regulator, RinA family
HFHCMLFP_00944 3.6e-23 V HNH nucleases
HFHCMLFP_00945 1e-25 L Phage terminase, small subunit
HFHCMLFP_00946 2.4e-216 S Terminase
HFHCMLFP_00947 6.9e-109 S Phage portal protein
HFHCMLFP_00948 7.6e-37 S Caudovirus prohead serine protease
HFHCMLFP_00949 4.1e-53 S Phage capsid family
HFHCMLFP_00950 1.5e-14 pi235
HFHCMLFP_00951 4.2e-11
HFHCMLFP_00952 3.2e-22 S Psort location Cytoplasmic, score
HFHCMLFP_00953 7.2e-11
HFHCMLFP_00954 5.5e-43 S phage tail protein
HFHCMLFP_00955 2.3e-20
HFHCMLFP_00957 4.4e-112 D Phage tail tape measure protein
HFHCMLFP_00958 4.5e-17 S phage tail
HFHCMLFP_00959 3.2e-222 tcdA2 GT2,GT4 LM gp58-like protein
HFHCMLFP_00960 3.8e-46
HFHCMLFP_00961 6.5e-28
HFHCMLFP_00962 5.5e-22
HFHCMLFP_00964 1.2e-27
HFHCMLFP_00965 2.9e-116 S peptidoglycan catabolic process
HFHCMLFP_00966 5.2e-23 doc
HFHCMLFP_00969 4e-187 cggR K Putative sugar-binding domain
HFHCMLFP_00970 1.1e-192 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFHCMLFP_00971 4.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HFHCMLFP_00972 7.8e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFHCMLFP_00973 1.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFHCMLFP_00974 6.1e-230 mdt(A) EGP Major facilitator Superfamily
HFHCMLFP_00975 6.2e-48
HFHCMLFP_00976 4.8e-293 clcA P chloride
HFHCMLFP_00977 2.4e-31 secG U Preprotein translocase
HFHCMLFP_00978 1.5e-140 est 3.1.1.1 S Serine aminopeptidase, S33
HFHCMLFP_00979 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFHCMLFP_00980 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFHCMLFP_00981 1.3e-176 yvdE K helix_turn _helix lactose operon repressor
HFHCMLFP_00982 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HFHCMLFP_00983 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HFHCMLFP_00984 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HFHCMLFP_00985 2.8e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HFHCMLFP_00986 5.5e-17 msmX P Belongs to the ABC transporter superfamily
HFHCMLFP_00987 1.2e-12 msmX P Belongs to the ABC transporter superfamily
HFHCMLFP_00988 2e-17
HFHCMLFP_00989 1.9e-23 ydcG K Helix-turn-helix XRE-family like proteins
HFHCMLFP_00990 3.7e-240 YSH1 S Metallo-beta-lactamase superfamily
HFHCMLFP_00991 3e-232 malE G Bacterial extracellular solute-binding protein
HFHCMLFP_00992 1.9e-147 malF G Binding-protein-dependent transport system inner membrane component
HFHCMLFP_00993 5.7e-166 malG P ABC-type sugar transport systems, permease components
HFHCMLFP_00994 1.3e-193 malK P ATPases associated with a variety of cellular activities
HFHCMLFP_00995 3.7e-105 3.2.2.20 K Acetyltransferase (GNAT) domain
HFHCMLFP_00996 9e-92 yxjI
HFHCMLFP_00997 4.1e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
HFHCMLFP_00998 6.6e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFHCMLFP_00999 5.5e-178 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HFHCMLFP_01000 1.3e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HFHCMLFP_01002 2.4e-164 natA S ABC transporter, ATP-binding protein
HFHCMLFP_01003 7.7e-217 ysdA CP ABC-2 family transporter protein
HFHCMLFP_01004 9e-98 dnaQ 2.7.7.7 L DNA polymerase III
HFHCMLFP_01005 7.5e-151 xth 3.1.11.2 L exodeoxyribonuclease III
HFHCMLFP_01006 2e-166 murB 1.3.1.98 M Cell wall formation
HFHCMLFP_01007 0.0 yjcE P Sodium proton antiporter
HFHCMLFP_01008 2.9e-96 puuR K Cupin domain
HFHCMLFP_01009 4e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFHCMLFP_01010 5.5e-147 potB P ABC transporter permease
HFHCMLFP_01011 4.1e-142 potC P ABC transporter permease
HFHCMLFP_01012 8e-207 potD P ABC transporter
HFHCMLFP_01014 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HFHCMLFP_01015 7.2e-110 K Transcriptional regulator
HFHCMLFP_01016 7.8e-184 V ABC transporter
HFHCMLFP_01017 1.3e-128 V AAA domain, putative AbiEii toxin, Type IV TA system
HFHCMLFP_01018 2.2e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFHCMLFP_01019 6.3e-167 ybbR S YbbR-like protein
HFHCMLFP_01020 2.4e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFHCMLFP_01021 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFHCMLFP_01023 0.0 pepF2 E Oligopeptidase F
HFHCMLFP_01024 1.5e-78 S VanZ like family
HFHCMLFP_01025 7.6e-132 yebC K Transcriptional regulatory protein
HFHCMLFP_01026 3.2e-153 comGA NU Type II IV secretion system protein
HFHCMLFP_01027 1.3e-168 comGB NU type II secretion system
HFHCMLFP_01028 1.9e-26
HFHCMLFP_01030 1.6e-22
HFHCMLFP_01031 1.9e-19
HFHCMLFP_01032 4.4e-10
HFHCMLFP_01033 1.8e-184 ytxK 2.1.1.72 L N-6 DNA Methylase
HFHCMLFP_01034 3.1e-51
HFHCMLFP_01035 2.4e-256 cycA E Amino acid permease
HFHCMLFP_01036 1.3e-147 arbV 2.3.1.51 I Phosphate acyltransferases
HFHCMLFP_01037 2.5e-163 arbx M Glycosyl transferase family 8
HFHCMLFP_01038 1.2e-180 arbY M family 8
HFHCMLFP_01039 4.3e-166 arbZ I Phosphate acyltransferases
HFHCMLFP_01040 0.0 rafA 3.2.1.22 G alpha-galactosidase
HFHCMLFP_01043 5.8e-70 S SdpI/YhfL protein family
HFHCMLFP_01044 8e-134 K response regulator
HFHCMLFP_01045 5.7e-272 T PhoQ Sensor
HFHCMLFP_01046 3.6e-75 yhbS S acetyltransferase
HFHCMLFP_01047 5.3e-14
HFHCMLFP_01048 1.5e-71 pheB 5.4.99.5 S Belongs to the UPF0735 family
HFHCMLFP_01049 1e-63
HFHCMLFP_01050 5.9e-55
HFHCMLFP_01051 3.1e-253 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HFHCMLFP_01053 2e-182 S response to antibiotic
HFHCMLFP_01054 4.5e-130 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HFHCMLFP_01055 3.8e-27 yjgN S Bacterial protein of unknown function (DUF898)
HFHCMLFP_01057 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HFHCMLFP_01058 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFHCMLFP_01059 5.2e-212 camS S sex pheromone
HFHCMLFP_01060 6.3e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFHCMLFP_01061 1.1e-264 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFHCMLFP_01062 8.9e-278 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFHCMLFP_01063 4.4e-194 yegS 2.7.1.107 G Lipid kinase
HFHCMLFP_01064 7.4e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFHCMLFP_01065 3.6e-219 yttB EGP Major facilitator Superfamily
HFHCMLFP_01066 5.6e-147 cof S Sucrose-6F-phosphate phosphohydrolase
HFHCMLFP_01067 8.1e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HFHCMLFP_01068 0.0 pepO 3.4.24.71 O Peptidase family M13
HFHCMLFP_01069 2.5e-264 ydiC1 EGP Major facilitator Superfamily
HFHCMLFP_01070 2.2e-79 K Acetyltransferase (GNAT) family
HFHCMLFP_01071 4.3e-166 degV S Uncharacterised protein, DegV family COG1307
HFHCMLFP_01072 1.9e-119 qmcA O prohibitin homologues
HFHCMLFP_01073 1.2e-28
HFHCMLFP_01075 1.9e-138 lys M Glycosyl hydrolases family 25
HFHCMLFP_01076 2.2e-60 S Protein of unknown function (DUF1093)
HFHCMLFP_01077 1.7e-60 S Domain of unknown function (DUF4828)
HFHCMLFP_01078 2.5e-175 mocA S Oxidoreductase
HFHCMLFP_01079 1.1e-237 yfmL 3.6.4.13 L DEAD DEAH box helicase
HFHCMLFP_01080 7.6e-56 chbA 2.7.1.196, 2.7.1.205 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HFHCMLFP_01081 7.3e-71 S Domain of unknown function (DUF3284)
HFHCMLFP_01083 4.4e-07
HFHCMLFP_01084 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HFHCMLFP_01085 2.7e-238 pepS E Thermophilic metalloprotease (M29)
HFHCMLFP_01086 9.4e-112 K Bacterial regulatory proteins, tetR family
HFHCMLFP_01088 1e-259 S Uncharacterized protein conserved in bacteria (DUF2252)
HFHCMLFP_01089 7.9e-180 yihY S Belongs to the UPF0761 family
HFHCMLFP_01090 7.2e-80 fld C Flavodoxin
HFHCMLFP_01091 4.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
HFHCMLFP_01092 1e-201 M Glycosyltransferase like family 2
HFHCMLFP_01094 3.1e-14
HFHCMLFP_01095 4e-198 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HFHCMLFP_01096 1.1e-167 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HFHCMLFP_01099 7.1e-33 L 4.5 Transposon and IS
HFHCMLFP_01100 2.5e-53 L 4.5 Transposon and IS
HFHCMLFP_01102 2.6e-118 L 4.5 Transposon and IS
HFHCMLFP_01103 1.3e-32 L 4.5 Transposon and IS
HFHCMLFP_01105 4e-64
HFHCMLFP_01106 1.9e-21 S WxL domain surface cell wall-binding
HFHCMLFP_01107 3.2e-128 S Cell surface protein
HFHCMLFP_01109 1.3e-288 N domain, Protein
HFHCMLFP_01110 4.8e-287 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCMLFP_01111 0.0 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFHCMLFP_01112 5.3e-150 licT2 K CAT RNA binding domain
HFHCMLFP_01113 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_01114 0.0 S Bacterial membrane protein YfhO
HFHCMLFP_01115 0.0 S Psort location CytoplasmicMembrane, score
HFHCMLFP_01116 2e-169 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HFHCMLFP_01117 8.8e-76
HFHCMLFP_01118 6.6e-168 yqjA S Putative aromatic acid exporter C-terminal domain
HFHCMLFP_01119 1e-10
HFHCMLFP_01120 1.6e-31 cspC K Cold shock protein
HFHCMLFP_01121 8.6e-84 yvbK 3.1.3.25 K GNAT family
HFHCMLFP_01122 1.9e-115 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HFHCMLFP_01123 5.5e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFHCMLFP_01124 2e-239 pbuX F xanthine permease
HFHCMLFP_01125 3.9e-204 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFHCMLFP_01126 1.8e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFHCMLFP_01127 2.8e-105
HFHCMLFP_01128 1.8e-104
HFHCMLFP_01129 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFHCMLFP_01130 1.4e-110 vanZ V VanZ like family
HFHCMLFP_01131 2e-152 glcU U sugar transport
HFHCMLFP_01132 5.6e-258 pgi 5.3.1.9 G Belongs to the GPI family
HFHCMLFP_01133 3.2e-225 L Pfam:Integrase_AP2
HFHCMLFP_01134 7.2e-32
HFHCMLFP_01135 1.5e-60 S Pyridoxamine 5'-phosphate oxidase
HFHCMLFP_01137 6.4e-65 S Domain of unknown function (DUF5067)
HFHCMLFP_01138 4.6e-35
HFHCMLFP_01139 5.1e-14 E IrrE N-terminal-like domain
HFHCMLFP_01140 2.3e-25 K Cro/C1-type HTH DNA-binding domain
HFHCMLFP_01141 5.5e-08 ropB K sequence-specific DNA binding
HFHCMLFP_01143 3e-13
HFHCMLFP_01145 1.2e-97
HFHCMLFP_01147 3.9e-15
HFHCMLFP_01150 4.6e-11 S ERF superfamily
HFHCMLFP_01151 2.9e-46 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFHCMLFP_01152 1.5e-64 L DnaD domain protein
HFHCMLFP_01153 1.3e-121 dnaC 3.4.21.53 L IstB-like ATP binding protein
HFHCMLFP_01155 2.5e-34
HFHCMLFP_01156 3e-65 S magnesium ion binding
HFHCMLFP_01158 9.6e-47
HFHCMLFP_01160 6.8e-20
HFHCMLFP_01163 1.1e-74
HFHCMLFP_01165 6.7e-234
HFHCMLFP_01166 7.3e-50
HFHCMLFP_01167 1.8e-16 L DNA packaging
HFHCMLFP_01168 3.6e-177 S Phage terminase large subunit
HFHCMLFP_01169 4.5e-179 S Phage portal protein, SPP1 Gp6-like
HFHCMLFP_01170 7.5e-60 S Phage Mu protein F like protein
HFHCMLFP_01172 6.3e-22 S Domain of unknown function (DUF4355)
HFHCMLFP_01173 2.7e-110
HFHCMLFP_01174 1.9e-145
HFHCMLFP_01175 4.8e-23 S Phage gp6-like head-tail connector protein
HFHCMLFP_01176 2.3e-10
HFHCMLFP_01177 1e-15 S exonuclease activity
HFHCMLFP_01179 1.7e-81 S Phage major tail protein 2
HFHCMLFP_01180 3.6e-20 S Pfam:Phage_TAC_12
HFHCMLFP_01182 8.1e-103 S Phage-related minor tail protein
HFHCMLFP_01183 2e-69 S Phage tail protein
HFHCMLFP_01184 1.3e-208 S peptidoglycan catabolic process
HFHCMLFP_01185 5.2e-27 S Domain of unknown function (DUF2479)
HFHCMLFP_01186 2.3e-63
HFHCMLFP_01188 2.3e-67 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HFHCMLFP_01189 6.8e-87 M Glycosyl hydrolases family 25
HFHCMLFP_01190 6.6e-66 S Domain of unknown function DUF1829
HFHCMLFP_01191 2.3e-53 S Domain of unknown function DUF1829
HFHCMLFP_01192 8.6e-47 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HFHCMLFP_01194 5.9e-152 F DNA/RNA non-specific endonuclease
HFHCMLFP_01195 1.3e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HFHCMLFP_01196 2.5e-230 wbbX GT2,GT4 M Glycosyl transferases group 1
HFHCMLFP_01197 5e-173 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HFHCMLFP_01198 3.8e-84 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
HFHCMLFP_01200 1.7e-79 tspO T TspO/MBR family
HFHCMLFP_01201 3.2e-13
HFHCMLFP_01202 1.7e-210 yttB EGP Major facilitator Superfamily
HFHCMLFP_01203 3.2e-104 S Protein of unknown function (DUF1211)
HFHCMLFP_01204 1.2e-285 pipD E Dipeptidase
HFHCMLFP_01206 7e-08
HFHCMLFP_01207 4e-125 G Phosphoglycerate mutase family
HFHCMLFP_01208 2.6e-120 K Bacterial regulatory proteins, tetR family
HFHCMLFP_01209 0.0 ycfI V ABC transporter, ATP-binding protein
HFHCMLFP_01210 0.0 yfiC V ABC transporter
HFHCMLFP_01211 3.5e-140 S NADPH-dependent FMN reductase
HFHCMLFP_01212 4e-164 1.13.11.2 S glyoxalase
HFHCMLFP_01213 1.5e-194 ampC V Beta-lactamase
HFHCMLFP_01214 1.1e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HFHCMLFP_01215 4.5e-111 tdk 2.7.1.21 F thymidine kinase
HFHCMLFP_01216 1.9e-176 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFHCMLFP_01217 2e-152 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFHCMLFP_01218 3.6e-185 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFHCMLFP_01219 2.6e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFHCMLFP_01220 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFHCMLFP_01221 4.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
HFHCMLFP_01222 3.3e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFHCMLFP_01223 3.1e-41 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFHCMLFP_01224 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFHCMLFP_01225 9.5e-286 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFHCMLFP_01226 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFHCMLFP_01227 1.3e-244 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFHCMLFP_01228 8.3e-70 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HFHCMLFP_01229 4.2e-31 ywzB S Protein of unknown function (DUF1146)
HFHCMLFP_01230 1.1e-178 mbl D Cell shape determining protein MreB Mrl
HFHCMLFP_01231 2.2e-18 epuA S DNA-directed RNA polymerase subunit beta
HFHCMLFP_01232 9.1e-55 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HFHCMLFP_01233 1.1e-30 S Protein of unknown function (DUF2969)
HFHCMLFP_01234 1.8e-223 rodA D Belongs to the SEDS family
HFHCMLFP_01235 9.5e-49 gcvH E glycine cleavage
HFHCMLFP_01236 1.2e-222 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HFHCMLFP_01237 6.8e-137 P Belongs to the nlpA lipoprotein family
HFHCMLFP_01239 3.5e-149 P Belongs to the nlpA lipoprotein family
HFHCMLFP_01240 6.1e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFHCMLFP_01241 3.7e-104 metI P ABC transporter permease
HFHCMLFP_01242 2.9e-142 sufC O FeS assembly ATPase SufC
HFHCMLFP_01243 5e-190 sufD O FeS assembly protein SufD
HFHCMLFP_01244 6.4e-221 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFHCMLFP_01245 1.3e-78 nifU C SUF system FeS assembly protein, NifU family
HFHCMLFP_01246 1.1e-280 sufB O assembly protein SufB
HFHCMLFP_01247 2.7e-22
HFHCMLFP_01248 2.9e-66 yueI S Protein of unknown function (DUF1694)
HFHCMLFP_01249 1.5e-180 S Protein of unknown function (DUF2785)
HFHCMLFP_01250 3e-116 yhfA S HAD hydrolase, family IA, variant 3
HFHCMLFP_01251 2.1e-152 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_01252 2.9e-82 usp6 T universal stress protein
HFHCMLFP_01253 9.2e-38
HFHCMLFP_01255 8.7e-240 rarA L recombination factor protein RarA
HFHCMLFP_01256 0.0 gshF 6.3.2.2, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
HFHCMLFP_01257 6e-76 yueI S Protein of unknown function (DUF1694)
HFHCMLFP_01258 3.1e-107 yktB S Belongs to the UPF0637 family
HFHCMLFP_01259 4.9e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HFHCMLFP_01260 6.2e-149 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HFHCMLFP_01261 4.7e-120 G alpha-ribazole phosphatase activity
HFHCMLFP_01262 2.7e-154 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFHCMLFP_01263 3.4e-169 IQ NAD dependent epimerase/dehydratase family
HFHCMLFP_01264 1.6e-137 pnuC H nicotinamide mononucleotide transporter
HFHCMLFP_01265 1.4e-133 dck 2.7.1.74 F deoxynucleoside kinase
HFHCMLFP_01266 1.2e-157 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HFHCMLFP_01267 0.0 oppA E ABC transporter, substratebinding protein
HFHCMLFP_01268 9.8e-158 T GHKL domain
HFHCMLFP_01269 2.1e-120 T Transcriptional regulatory protein, C terminal
HFHCMLFP_01270 7.5e-169 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
HFHCMLFP_01271 5.2e-99 S ABC-2 family transporter protein
HFHCMLFP_01272 3.3e-158 K Transcriptional regulator
HFHCMLFP_01273 3e-77 yphH S Cupin domain
HFHCMLFP_01274 5.5e-55 yphJ 4.1.1.44 S decarboxylase
HFHCMLFP_01275 8.6e-116 GM NAD(P)H-binding
HFHCMLFP_01276 2e-34 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HFHCMLFP_01277 6.6e-237 L Transposase
HFHCMLFP_01278 7.5e-120 gst 2.5.1.18 O Glutathione S-transferase, C-terminal domain
HFHCMLFP_01279 2.7e-109 K Psort location Cytoplasmic, score
HFHCMLFP_01280 1.2e-155 2.3.1.128 K Acetyltransferase (GNAT) domain
HFHCMLFP_01281 1.2e-31 K Acetyltransferase (GNAT) domain
HFHCMLFP_01282 7.7e-41 K Acetyltransferase (GNAT) domain
HFHCMLFP_01283 7.5e-132 T Histidine kinase
HFHCMLFP_01284 2.6e-87 K helix_turn_helix, arabinose operon control protein
HFHCMLFP_01285 3.4e-149 P Bacterial extracellular solute-binding protein
HFHCMLFP_01286 1.7e-156 fbpC 3.6.3.30, 3.6.3.31 P TOBE domain
HFHCMLFP_01287 3.5e-249 sfuB P Binding-protein-dependent transport system inner membrane component
HFHCMLFP_01288 8.2e-154 S Uncharacterised protein, DegV family COG1307
HFHCMLFP_01289 1.2e-101 desR K helix_turn_helix, Lux Regulon
HFHCMLFP_01290 1.7e-151 desK 2.7.13.3 T Histidine kinase
HFHCMLFP_01291 3.1e-96 yvfS V ABC-2 type transporter
HFHCMLFP_01292 1.2e-123 yvfR V ABC transporter
HFHCMLFP_01293 4.9e-209
HFHCMLFP_01294 6.1e-67 K helix_turn_helix, mercury resistance
HFHCMLFP_01295 1.1e-47 S Protein of unknown function (DUF2568)
HFHCMLFP_01296 6.2e-50 S Protein of unknown function C-terminus (DUF2399)
HFHCMLFP_01297 7e-47 S Protein of unknown function C-terminus (DUF2399)
HFHCMLFP_01298 9.1e-121 K Acetyltransferase (GNAT) domain
HFHCMLFP_01299 3.5e-42 L RelB antitoxin
HFHCMLFP_01300 1.5e-46 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HFHCMLFP_01302 0.0 yhgF K Tex-like protein N-terminal domain protein
HFHCMLFP_01304 1.7e-21 XK27_01125 L PFAM IS66 Orf2 family protein
HFHCMLFP_01305 1.3e-125 L Transposase IS66 family
HFHCMLFP_01306 1.5e-217 sthIM 2.1.1.72 L DNA methylase
HFHCMLFP_01307 0.0 res_1 3.1.21.5 S Type III restriction
HFHCMLFP_01308 3.1e-17 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HFHCMLFP_01309 7.1e-16 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HFHCMLFP_01310 4.4e-117 L AAA ATPase domain
HFHCMLFP_01311 1.1e-59 F UvrD/REP helicase N-terminal domain
HFHCMLFP_01312 1.6e-89 L PFAM transposase IS116 IS110 IS902 family
HFHCMLFP_01313 6.4e-18 L PFAM transposase IS116 IS110 IS902 family
HFHCMLFP_01314 1.2e-68 K Cro/C1-type HTH DNA-binding domain
HFHCMLFP_01315 1.8e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFHCMLFP_01316 4.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
HFHCMLFP_01317 5.8e-276 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFHCMLFP_01318 6.2e-214 iscS2 2.8.1.7 E Aminotransferase class V
HFHCMLFP_01319 3.9e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFHCMLFP_01320 1.7e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFHCMLFP_01321 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFHCMLFP_01322 7e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HFHCMLFP_01323 4.3e-115 S Haloacid dehalogenase-like hydrolase
HFHCMLFP_01324 2e-118 radC L DNA repair protein
HFHCMLFP_01325 1e-179 mreB D cell shape determining protein MreB
HFHCMLFP_01326 7.2e-150 mreC M Involved in formation and maintenance of cell shape
HFHCMLFP_01327 2.3e-85 mreD M rod shape-determining protein MreD
HFHCMLFP_01328 1.3e-114 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HFHCMLFP_01329 2.6e-141 minD D Belongs to the ParA family
HFHCMLFP_01330 1.2e-109 artQ P ABC transporter permease
HFHCMLFP_01331 2e-112 glnQ 3.6.3.21 E ABC transporter
HFHCMLFP_01332 1.2e-151 aatB ET ABC transporter substrate-binding protein
HFHCMLFP_01333 4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFHCMLFP_01334 4.2e-45
HFHCMLFP_01335 9.8e-79 mraZ K Belongs to the MraZ family
HFHCMLFP_01336 1.1e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFHCMLFP_01337 3.1e-49 ftsL D cell division protein FtsL
HFHCMLFP_01338 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HFHCMLFP_01339 2e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFHCMLFP_01340 6.4e-265 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFHCMLFP_01341 1.8e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFHCMLFP_01342 9.8e-155 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFHCMLFP_01343 4.2e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFHCMLFP_01344 5.9e-225 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFHCMLFP_01345 8.7e-78 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFHCMLFP_01346 2.4e-44 yggT S integral membrane protein
HFHCMLFP_01347 1.7e-145 ylmH S S4 domain protein
HFHCMLFP_01348 8.8e-86 divIVA D DivIVA protein
HFHCMLFP_01349 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFHCMLFP_01350 6.9e-36 cspA K Cold shock protein
HFHCMLFP_01351 6.7e-154 pstS P Phosphate
HFHCMLFP_01352 2.5e-264 ydiC1 EGP Major facilitator Superfamily
HFHCMLFP_01353 5.1e-210 yaaN P Toxic anion resistance protein (TelA)
HFHCMLFP_01354 2e-115 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HFHCMLFP_01355 1.2e-94 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HFHCMLFP_01356 1.2e-28
HFHCMLFP_01357 4.8e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFHCMLFP_01358 1.3e-218 iscS 2.8.1.7 E Aminotransferase class V
HFHCMLFP_01359 2.9e-57 XK27_04120 S Putative amino acid metabolism
HFHCMLFP_01360 0.0 uvrA2 L ABC transporter
HFHCMLFP_01361 2.6e-241 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFHCMLFP_01363 9.9e-123 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HFHCMLFP_01364 1.8e-116 S Repeat protein
HFHCMLFP_01365 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFHCMLFP_01366 1.4e-244 els S Sterol carrier protein domain
HFHCMLFP_01367 1.6e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HFHCMLFP_01368 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFHCMLFP_01369 2.9e-31 ykzG S Belongs to the UPF0356 family
HFHCMLFP_01370 9.5e-69
HFHCMLFP_01371 2.5e-46
HFHCMLFP_01372 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFHCMLFP_01373 5.2e-89 S E1-E2 ATPase
HFHCMLFP_01374 1.5e-211 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HFHCMLFP_01375 6.2e-182 pdhB 1.2.4.1, 1.2.4.4 C Transketolase, C-terminal domain protein
HFHCMLFP_01376 1.6e-262 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFHCMLFP_01377 3.7e-260 lpdA 1.8.1.4 C Dehydrogenase
HFHCMLFP_01378 3.7e-157 1.1.1.27 C L-malate dehydrogenase activity
HFHCMLFP_01379 2.4e-46 yktA S Belongs to the UPF0223 family
HFHCMLFP_01380 1.3e-145 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HFHCMLFP_01381 0.0 typA T GTP-binding protein TypA
HFHCMLFP_01382 7.6e-211 ftsW D Belongs to the SEDS family
HFHCMLFP_01383 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HFHCMLFP_01384 2.5e-62 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HFHCMLFP_01385 5.9e-100 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HFHCMLFP_01386 1.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFHCMLFP_01387 7.1e-181 ylbL T Belongs to the peptidase S16 family
HFHCMLFP_01388 2.1e-112 comEA L Competence protein ComEA
HFHCMLFP_01389 0.0 comEC S Competence protein ComEC
HFHCMLFP_01390 4.9e-169 holA 2.7.7.7 L DNA polymerase III delta subunit
HFHCMLFP_01391 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
HFHCMLFP_01392 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFHCMLFP_01393 1.1e-50
HFHCMLFP_01394 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFHCMLFP_01395 4.9e-165 S Tetratricopeptide repeat
HFHCMLFP_01396 2.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFHCMLFP_01397 0.0 yknV V ABC transporter
HFHCMLFP_01398 1.4e-221 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFHCMLFP_01399 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFHCMLFP_01400 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HFHCMLFP_01401 7.8e-48 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HFHCMLFP_01402 1.3e-20
HFHCMLFP_01403 1.5e-259 arpJ P ABC transporter permease
HFHCMLFP_01404 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFHCMLFP_01405 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFHCMLFP_01406 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HFHCMLFP_01407 6.7e-170 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HFHCMLFP_01408 6.6e-131 fruR K DeoR C terminal sensor domain
HFHCMLFP_01409 3.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFHCMLFP_01410 0.0 oatA I Acyltransferase
HFHCMLFP_01411 8.6e-184 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFHCMLFP_01412 1e-142 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HFHCMLFP_01413 4.1e-48 yrvD S Lipopolysaccharide assembly protein A domain
HFHCMLFP_01414 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFHCMLFP_01415 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HFHCMLFP_01416 2.8e-94 M1-874 K Domain of unknown function (DUF1836)
HFHCMLFP_01417 1.3e-303 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
HFHCMLFP_01418 1e-125
HFHCMLFP_01419 2.5e-18 S Protein of unknown function (DUF2929)
HFHCMLFP_01420 0.0 dnaE 2.7.7.7 L DNA polymerase
HFHCMLFP_01421 7e-178 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HFHCMLFP_01422 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HFHCMLFP_01423 1.5e-72 yeaL S Protein of unknown function (DUF441)
HFHCMLFP_01424 4.9e-162 cvfB S S1 domain
HFHCMLFP_01425 4e-164 xerD D recombinase XerD
HFHCMLFP_01426 2e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFHCMLFP_01427 2e-124 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFHCMLFP_01428 5.5e-107 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFHCMLFP_01429 6.7e-136 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFHCMLFP_01430 1e-94 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFHCMLFP_01431 3.2e-45 fer C 4Fe-4S single cluster domain of Ferredoxin I
HFHCMLFP_01432 1.9e-178 ypbB 5.1.3.1 S Helix-turn-helix domain
HFHCMLFP_01433 8.5e-265 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HFHCMLFP_01434 6.1e-66 M Lysin motif
HFHCMLFP_01435 5.8e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HFHCMLFP_01436 2.1e-225 rpsA 1.17.7.4 J Ribosomal protein S1
HFHCMLFP_01437 2e-244 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HFHCMLFP_01438 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFHCMLFP_01439 2.3e-237 S Tetratricopeptide repeat protein
HFHCMLFP_01440 2.6e-147 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFHCMLFP_01441 7.5e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFHCMLFP_01442 1.3e-84
HFHCMLFP_01443 0.0 yfmR S ABC transporter, ATP-binding protein
HFHCMLFP_01444 6e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFHCMLFP_01445 5.7e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFHCMLFP_01446 2.1e-114 hly S protein, hemolysin III
HFHCMLFP_01447 5e-146 DegV S EDD domain protein, DegV family
HFHCMLFP_01448 6.9e-153 ypmR E GDSL-like Lipase/Acylhydrolase
HFHCMLFP_01449 5.2e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HFHCMLFP_01450 7.7e-85 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFHCMLFP_01451 1.1e-39 yozE S Belongs to the UPF0346 family
HFHCMLFP_01452 9.3e-240 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HFHCMLFP_01453 5.4e-27 K Helix-turn-helix domain
HFHCMLFP_01454 5e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFHCMLFP_01455 1.1e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFHCMLFP_01456 5.1e-145 dprA LU DNA protecting protein DprA
HFHCMLFP_01457 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFHCMLFP_01458 3.2e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HFHCMLFP_01459 2.1e-168 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HFHCMLFP_01460 7.2e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HFHCMLFP_01461 2.6e-258 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HFHCMLFP_01462 1.8e-172 lacX 5.1.3.3 G Aldose 1-epimerase
HFHCMLFP_01463 1.7e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFHCMLFP_01464 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFHCMLFP_01465 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFHCMLFP_01466 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HFHCMLFP_01467 5.6e-171 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFHCMLFP_01468 3.4e-180 K LysR substrate binding domain
HFHCMLFP_01469 8.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
HFHCMLFP_01470 1.2e-208 xerS L Belongs to the 'phage' integrase family
HFHCMLFP_01471 8.1e-39
HFHCMLFP_01472 0.0 ysaB V FtsX-like permease family
HFHCMLFP_01473 6.3e-137 XK27_05695 V ABC transporter, ATP-binding protein
HFHCMLFP_01474 4.8e-171 T PhoQ Sensor
HFHCMLFP_01475 1.4e-122 T Transcriptional regulatory protein, C terminal
HFHCMLFP_01476 1e-190 EGP Transmembrane secretion effector
HFHCMLFP_01477 5.7e-49 msi198 K Acetyltransferase (GNAT) domain
HFHCMLFP_01478 4.5e-70 K Acetyltransferase (GNAT) domain
HFHCMLFP_01479 3.7e-111 nfnB 1.5.1.34 C Nitroreductase family
HFHCMLFP_01480 3.8e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HFHCMLFP_01481 2.1e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HFHCMLFP_01482 1.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HFHCMLFP_01483 2.3e-131 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HFHCMLFP_01484 1.3e-123 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HFHCMLFP_01485 5.2e-113 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HFHCMLFP_01486 1.8e-104 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HFHCMLFP_01487 2.4e-229 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HFHCMLFP_01488 3.4e-112 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HFHCMLFP_01489 2.8e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HFHCMLFP_01490 4.1e-206 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HFHCMLFP_01491 2.3e-99 3.6.1.13 L Belongs to the Nudix hydrolase family
HFHCMLFP_01492 5.9e-160 degV S EDD domain protein, DegV family
HFHCMLFP_01493 0.0 FbpA K Fibronectin-binding protein
HFHCMLFP_01494 1.2e-49 S MazG-like family
HFHCMLFP_01495 3.4e-195 pfoS S Phosphotransferase system, EIIC
HFHCMLFP_01496 4e-178 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFHCMLFP_01497 1.1e-205 bfmBB 2.3.1.168, 2.3.1.61 C 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HFHCMLFP_01498 1.7e-182 bfmBAB 1.2.4.1, 1.2.4.4 C Transketolase, pyrimidine binding domain
HFHCMLFP_01499 1.9e-186 bfmBAA 1.2.4.4 C Dehydrogenase E1 component
HFHCMLFP_01500 2e-258 lpdA 1.8.1.4 C 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
HFHCMLFP_01501 8.1e-202 buk 2.7.2.7 C Acetokinase family
HFHCMLFP_01502 1.4e-148 pta 2.3.1.19, 2.3.1.8 C Phosphate acetyl/butaryl transferase
HFHCMLFP_01503 8.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFHCMLFP_01504 3.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFHCMLFP_01505 2.4e-156 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFHCMLFP_01506 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HFHCMLFP_01507 3e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HFHCMLFP_01508 2.7e-238 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFHCMLFP_01509 1.6e-179 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HFHCMLFP_01510 2.6e-236 pyrP F Permease
HFHCMLFP_01511 1.7e-96 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFHCMLFP_01512 5e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFHCMLFP_01513 4.3e-80 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFHCMLFP_01514 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HFHCMLFP_01515 1.7e-45 S Family of unknown function (DUF5322)
HFHCMLFP_01516 1.7e-69 rnhA 3.1.26.4 L Ribonuclease HI
HFHCMLFP_01517 5.1e-110 XK27_02070 S Nitroreductase family
HFHCMLFP_01518 2.6e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFHCMLFP_01519 1.8e-48
HFHCMLFP_01520 1.8e-273 S Mga helix-turn-helix domain
HFHCMLFP_01521 2e-38 nrdH O Glutaredoxin
HFHCMLFP_01522 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFHCMLFP_01523 2.4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFHCMLFP_01524 1.1e-161 K Transcriptional regulator
HFHCMLFP_01525 0.0 pepO 3.4.24.71 O Peptidase family M13
HFHCMLFP_01526 7.4e-194 lplA 6.3.1.20 H Lipoate-protein ligase
HFHCMLFP_01527 3.9e-34
HFHCMLFP_01528 1.2e-171 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HFHCMLFP_01529 1.7e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HFHCMLFP_01530 2.3e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFHCMLFP_01531 1.3e-107 ypsA S Belongs to the UPF0398 family
HFHCMLFP_01532 5.1e-121 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFHCMLFP_01533 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HFHCMLFP_01534 4.4e-85 comEB 3.5.4.12 F ComE operon protein 2
HFHCMLFP_01535 2.5e-113 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFHCMLFP_01536 1.8e-113 dnaD L DnaD domain protein
HFHCMLFP_01537 1.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HFHCMLFP_01538 2.9e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HFHCMLFP_01539 7.1e-86 ypmB S Protein conserved in bacteria
HFHCMLFP_01540 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HFHCMLFP_01541 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HFHCMLFP_01542 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HFHCMLFP_01543 3.2e-167 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HFHCMLFP_01544 3.9e-179 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HFHCMLFP_01545 4.1e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFHCMLFP_01546 5.2e-264 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HFHCMLFP_01547 3.6e-174
HFHCMLFP_01548 4.8e-142
HFHCMLFP_01549 8.2e-60 yitW S Iron-sulfur cluster assembly protein
HFHCMLFP_01550 3.5e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HFHCMLFP_01551 6e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFHCMLFP_01552 1.8e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
HFHCMLFP_01553 3.4e-188 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFHCMLFP_01554 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFHCMLFP_01555 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HFHCMLFP_01556 2e-171 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HFHCMLFP_01558 2e-41
HFHCMLFP_01559 2.3e-53
HFHCMLFP_01560 3.3e-141 recO L Involved in DNA repair and RecF pathway recombination
HFHCMLFP_01561 9.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFHCMLFP_01562 4e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HFHCMLFP_01563 3.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HFHCMLFP_01564 2e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFHCMLFP_01565 5.9e-180 phoH T phosphate starvation-inducible protein PhoH
HFHCMLFP_01567 6.1e-68 yqeY S YqeY-like protein
HFHCMLFP_01568 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HFHCMLFP_01569 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HFHCMLFP_01570 9.1e-164 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HFHCMLFP_01571 7.4e-169 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFHCMLFP_01572 1.3e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HFHCMLFP_01573 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HFHCMLFP_01574 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HFHCMLFP_01575 1.7e-35 XK27_04345 3.6.1.1 C Inorganic pyrophosphatase
HFHCMLFP_01576 1.7e-82 1.6.5.5 C nadph quinone reductase
HFHCMLFP_01577 9.3e-278
HFHCMLFP_01578 6.9e-156 V ABC transporter
HFHCMLFP_01579 3e-83 FG adenosine 5'-monophosphoramidase activity
HFHCMLFP_01580 1e-243 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
HFHCMLFP_01581 2.6e-117 3.1.3.18 J HAD-hyrolase-like
HFHCMLFP_01582 4.2e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFHCMLFP_01583 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFHCMLFP_01584 1.3e-43
HFHCMLFP_01585 6.5e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFHCMLFP_01586 1e-173 prmA J Ribosomal protein L11 methyltransferase
HFHCMLFP_01587 2.9e-87 XK27_03960 S Protein of unknown function (DUF3013)
HFHCMLFP_01588 7.3e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HFHCMLFP_01589 5.3e-37
HFHCMLFP_01590 3.8e-66 S Protein of unknown function (DUF1093)
HFHCMLFP_01591 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_01592 6.3e-19
HFHCMLFP_01593 2.7e-48
HFHCMLFP_01594 1.3e-84 XK27_02675 K Acetyltransferase (GNAT) domain
HFHCMLFP_01596 5.6e-52 1.6.5.2 S Flavodoxin-like fold
HFHCMLFP_01597 2.1e-34 1.6.5.2 S Flavodoxin-like fold
HFHCMLFP_01598 2.6e-95 K Bacterial regulatory proteins, tetR family
HFHCMLFP_01599 1.4e-155 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
HFHCMLFP_01600 3.6e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HFHCMLFP_01601 4.5e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFHCMLFP_01602 5.3e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFHCMLFP_01603 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HFHCMLFP_01604 5.3e-57
HFHCMLFP_01605 1.5e-83 6.3.3.2 S ASCH
HFHCMLFP_01606 4.9e-24
HFHCMLFP_01607 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFHCMLFP_01608 1.9e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFHCMLFP_01609 9.7e-309 dnaK O Heat shock 70 kDa protein
HFHCMLFP_01610 9.8e-98 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFHCMLFP_01611 1.4e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFHCMLFP_01612 4.1e-225 hemN H Involved in the biosynthesis of porphyrin-containing compound
HFHCMLFP_01613 8.5e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HFHCMLFP_01614 1.3e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFHCMLFP_01615 3.5e-143 terC P Integral membrane protein TerC family
HFHCMLFP_01616 4.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFHCMLFP_01617 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFHCMLFP_01618 1.9e-44 ylxQ J ribosomal protein
HFHCMLFP_01619 1.7e-45 ylxR K Protein of unknown function (DUF448)
HFHCMLFP_01620 2.8e-195 nusA K Participates in both transcription termination and antitermination
HFHCMLFP_01621 1.7e-84 rimP J Required for maturation of 30S ribosomal subunits
HFHCMLFP_01622 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFHCMLFP_01623 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFHCMLFP_01624 9.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HFHCMLFP_01625 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HFHCMLFP_01626 1.3e-139 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFHCMLFP_01627 1.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFHCMLFP_01628 5.9e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HFHCMLFP_01629 1e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFHCMLFP_01630 1e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
HFHCMLFP_01631 1.5e-45 yazA L GIY-YIG catalytic domain protein
HFHCMLFP_01632 3.2e-130 yabB 2.1.1.223 L Methyltransferase small domain
HFHCMLFP_01633 1.1e-218 M Glycosyl hydrolases family 25
HFHCMLFP_01634 1.5e-66 S Pfam:Phage_holin_6_1
HFHCMLFP_01636 3e-63
HFHCMLFP_01637 1e-18 3.1.4.46 C glycerophosphodiester phosphodiesterase activity
HFHCMLFP_01638 3.9e-50 S Prophage endopeptidase tail
HFHCMLFP_01639 1.6e-41 S phage tail
HFHCMLFP_01640 1.8e-266 S peptidoglycan catabolic process
HFHCMLFP_01641 1.8e-21
HFHCMLFP_01642 7.8e-74 S Pfam:Phage_TTP_1
HFHCMLFP_01643 6.4e-29
HFHCMLFP_01644 1.4e-65 S exonuclease activity
HFHCMLFP_01645 1.5e-37 S Phage head-tail joining protein
HFHCMLFP_01646 5.2e-25 S Phage gp6-like head-tail connector protein
HFHCMLFP_01647 3.3e-20 S peptidase activity
HFHCMLFP_01648 2.4e-215 S peptidase activity
HFHCMLFP_01649 9.8e-112 S peptidase activity
HFHCMLFP_01650 4e-234 S Phage portal protein
HFHCMLFP_01652 0.0 S Phage Terminase
HFHCMLFP_01653 1.8e-78 S Phage terminase, small subunit
HFHCMLFP_01654 6.1e-154 L 4.5 Transposon and IS
HFHCMLFP_01655 2.5e-43 L 4.5 Transposon and IS
HFHCMLFP_01656 3.3e-124 S GcrA cell cycle regulator
HFHCMLFP_01659 2.4e-48
HFHCMLFP_01662 2.5e-27
HFHCMLFP_01664 5.9e-233 S DNA helicase activity
HFHCMLFP_01665 8e-154 S calcium ion binding
HFHCMLFP_01672 2.5e-79 K Phage regulatory protein
HFHCMLFP_01675 5e-15
HFHCMLFP_01676 5.2e-107 K BRO family, N-terminal domain
HFHCMLFP_01677 1.9e-10
HFHCMLFP_01679 4.5e-50 ps115 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_01680 2.8e-22 E Zn peptidase
HFHCMLFP_01681 4.6e-67 tcdC
HFHCMLFP_01685 3.8e-09
HFHCMLFP_01686 6.9e-103 L Belongs to the 'phage' integrase family
HFHCMLFP_01687 2.6e-123 plsC 2.3.1.51 I Acyltransferase
HFHCMLFP_01688 2e-218 yfnA E Amino Acid
HFHCMLFP_01689 6.7e-142 yejC S Protein of unknown function (DUF1003)
HFHCMLFP_01690 0.0 mdlB V ABC transporter
HFHCMLFP_01691 0.0 mdlA V ABC transporter
HFHCMLFP_01692 4.8e-29 yneF S UPF0154 protein
HFHCMLFP_01693 4.1e-37 ynzC S UPF0291 protein
HFHCMLFP_01694 9.4e-20
HFHCMLFP_01696 2.9e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFHCMLFP_01697 5.3e-144 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HFHCMLFP_01698 3.2e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFHCMLFP_01699 2.9e-38 ylqC S Belongs to the UPF0109 family
HFHCMLFP_01700 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HFHCMLFP_01701 6.3e-231 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFHCMLFP_01702 3.8e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFHCMLFP_01704 8.8e-53
HFHCMLFP_01705 4.1e-181 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFHCMLFP_01706 0.0 smc D Required for chromosome condensation and partitioning
HFHCMLFP_01707 3.8e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFHCMLFP_01708 0.0 oppA1 E ABC transporter substrate-binding protein
HFHCMLFP_01709 1.4e-135 oppC EP Binding-protein-dependent transport system inner membrane component
HFHCMLFP_01710 9.2e-170 oppB P ABC transporter permease
HFHCMLFP_01711 4.1e-178 oppF P Belongs to the ABC transporter superfamily
HFHCMLFP_01712 5.7e-194 oppD P Belongs to the ABC transporter superfamily
HFHCMLFP_01713 3e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFHCMLFP_01714 1.7e-185 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFHCMLFP_01715 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFHCMLFP_01716 4.6e-310 yloV S DAK2 domain fusion protein YloV
HFHCMLFP_01717 2.3e-57 asp S Asp23 family, cell envelope-related function
HFHCMLFP_01718 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HFHCMLFP_01719 2.3e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
HFHCMLFP_01720 3.6e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HFHCMLFP_01721 7.6e-174 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFHCMLFP_01722 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HFHCMLFP_01723 9.7e-135 stp 3.1.3.16 T phosphatase
HFHCMLFP_01724 4.4e-255 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFHCMLFP_01725 2.2e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFHCMLFP_01726 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFHCMLFP_01727 1.5e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFHCMLFP_01728 1.3e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFHCMLFP_01729 1.9e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HFHCMLFP_01730 1.2e-91 rssA S Patatin-like phospholipase
HFHCMLFP_01731 1.9e-49
HFHCMLFP_01733 0.0 recN L May be involved in recombinational repair of damaged DNA
HFHCMLFP_01734 4.4e-74 argR K Regulates arginine biosynthesis genes
HFHCMLFP_01735 3.6e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HFHCMLFP_01736 1.8e-148 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFHCMLFP_01737 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFHCMLFP_01738 4.5e-199 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFHCMLFP_01739 7.9e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFHCMLFP_01740 1.1e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFHCMLFP_01741 2.2e-76 yqhY S Asp23 family, cell envelope-related function
HFHCMLFP_01742 1.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFHCMLFP_01744 2.7e-202 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HFHCMLFP_01745 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HFHCMLFP_01746 1.1e-56 ysxB J Cysteine protease Prp
HFHCMLFP_01747 4.9e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
HFHCMLFP_01748 3.2e-11
HFHCMLFP_01749 5.5e-16
HFHCMLFP_01751 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HFHCMLFP_01752 5.4e-261 glnA 6.3.1.2 E glutamine synthetase
HFHCMLFP_01753 1e-60 glnR K Transcriptional regulator
HFHCMLFP_01754 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HFHCMLFP_01755 1.2e-238 ynbB 4.4.1.1 P aluminum resistance
HFHCMLFP_01756 2.9e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFHCMLFP_01757 1.5e-25 WQ51_02665 S Protein of unknown function (DUF3042)
HFHCMLFP_01758 2.6e-73 yqhL P Rhodanese-like protein
HFHCMLFP_01759 1.8e-178 glk 2.7.1.2 G Glucokinase
HFHCMLFP_01760 6.2e-41 yqgQ S Bacterial protein of unknown function (DUF910)
HFHCMLFP_01761 2.1e-120 gluP 3.4.21.105 S Peptidase, S54 family
HFHCMLFP_01762 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HFHCMLFP_01763 0.0 S Bacterial membrane protein YfhO
HFHCMLFP_01764 2.9e-53 yneR S Belongs to the HesB IscA family
HFHCMLFP_01765 6.9e-116 vraR K helix_turn_helix, Lux Regulon
HFHCMLFP_01766 2.4e-179 vraS 2.7.13.3 T Histidine kinase
HFHCMLFP_01767 7.8e-118 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HFHCMLFP_01768 6.9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFHCMLFP_01769 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HFHCMLFP_01770 1.5e-206 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFHCMLFP_01771 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFHCMLFP_01772 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFHCMLFP_01773 6.3e-66 yodB K Transcriptional regulator, HxlR family
HFHCMLFP_01775 7.3e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFHCMLFP_01776 5.1e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFHCMLFP_01777 1.9e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HFHCMLFP_01778 6.4e-174 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFHCMLFP_01779 2.9e-290 arlS 2.7.13.3 T Histidine kinase
HFHCMLFP_01780 7.9e-123 K response regulator
HFHCMLFP_01781 1.1e-267 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFHCMLFP_01782 8.8e-37 yhcX S Psort location Cytoplasmic, score
HFHCMLFP_01783 1.6e-97 yceD S Uncharacterized ACR, COG1399
HFHCMLFP_01784 2.8e-210 ylbM S Belongs to the UPF0348 family
HFHCMLFP_01785 1.3e-136 yccK Q ubiE/COQ5 methyltransferase family
HFHCMLFP_01786 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFHCMLFP_01787 5.6e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HFHCMLFP_01788 8.2e-122 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFHCMLFP_01789 3.8e-48 yhbY J RNA-binding protein
HFHCMLFP_01790 2.7e-205 yqeH S Ribosome biogenesis GTPase YqeH
HFHCMLFP_01791 2.9e-96 yqeG S HAD phosphatase, family IIIA
HFHCMLFP_01792 6e-171 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFHCMLFP_01793 2.8e-190 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFHCMLFP_01794 4.8e-122 mhqD S Dienelactone hydrolase family
HFHCMLFP_01795 5.8e-180 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
HFHCMLFP_01796 2.8e-97 yvdD 3.2.2.10 S Belongs to the LOG family
HFHCMLFP_01797 8.7e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFHCMLFP_01798 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HFHCMLFP_01799 1.5e-77 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFHCMLFP_01800 2.6e-129 S SseB protein N-terminal domain
HFHCMLFP_01801 1.6e-53
HFHCMLFP_01802 1.3e-102 yrgI 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
HFHCMLFP_01803 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFHCMLFP_01805 1.2e-171 dnaI L Primosomal protein DnaI
HFHCMLFP_01806 8.7e-251 dnaB L replication initiation and membrane attachment
HFHCMLFP_01807 1.2e-79 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFHCMLFP_01808 1.4e-99 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFHCMLFP_01809 2.6e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFHCMLFP_01810 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFHCMLFP_01811 4.2e-119 ybhL S Inhibitor of apoptosis-promoting Bax1
HFHCMLFP_01812 2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HFHCMLFP_01813 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HFHCMLFP_01814 1.1e-115 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFHCMLFP_01815 1.5e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HFHCMLFP_01817 1.8e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFHCMLFP_01818 3.9e-147 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HFHCMLFP_01820 9.1e-215 ecsB U ABC transporter
HFHCMLFP_01821 3.1e-133 ecsA V ABC transporter, ATP-binding protein
HFHCMLFP_01822 1.6e-76 hit FG histidine triad
HFHCMLFP_01823 3.9e-60 yhaH S YtxH-like protein
HFHCMLFP_01824 3.1e-159 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFHCMLFP_01825 1.4e-181 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFHCMLFP_01826 1e-54 yheA S Control of competence regulator ComK, YlbF/YmcA
HFHCMLFP_01827 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HFHCMLFP_01828 8e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFHCMLFP_01829 5.3e-75 argR K Regulates arginine biosynthesis genes
HFHCMLFP_01830 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HFHCMLFP_01832 3.4e-67
HFHCMLFP_01833 2.1e-22
HFHCMLFP_01834 5.2e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HFHCMLFP_01835 0.0 glpQ 3.1.4.46 C phosphodiesterase
HFHCMLFP_01836 5.1e-122 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HFHCMLFP_01837 3.2e-68 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFHCMLFP_01838 2.3e-136 yhfI S Metallo-beta-lactamase superfamily
HFHCMLFP_01839 4.8e-93 traP 1.14.99.57, 6.2.1.3 S heme oxygenase (decyclizing) activity
HFHCMLFP_01840 0.0 V ABC transporter (permease)
HFHCMLFP_01841 5.7e-138 bceA V ABC transporter
HFHCMLFP_01842 5.9e-123 K response regulator
HFHCMLFP_01843 2.6e-208 T PhoQ Sensor
HFHCMLFP_01844 6.4e-110 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFHCMLFP_01845 0.0 copB 3.6.3.4 P P-type ATPase
HFHCMLFP_01846 7.9e-76 copR K Copper transport repressor CopY TcrY
HFHCMLFP_01847 1.6e-235 purD 6.3.4.13 F Belongs to the GARS family
HFHCMLFP_01848 3.8e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HFHCMLFP_01849 2.5e-98 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFHCMLFP_01850 4.5e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HFHCMLFP_01851 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFHCMLFP_01852 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFHCMLFP_01853 1.4e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFHCMLFP_01854 6.4e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFHCMLFP_01855 3.1e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HFHCMLFP_01856 2.5e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFHCMLFP_01857 3.2e-78 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFHCMLFP_01858 4.7e-103 thiT S Thiamine transporter protein (Thia_YuaJ)
HFHCMLFP_01859 5.9e-258 iolT EGP Major facilitator Superfamily
HFHCMLFP_01860 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFHCMLFP_01861 2.7e-39 ptsH G phosphocarrier protein HPR
HFHCMLFP_01862 2e-28
HFHCMLFP_01863 0.0 clpE O Belongs to the ClpA ClpB family
HFHCMLFP_01864 2.8e-45 XK27_09445 S Domain of unknown function (DUF1827)
HFHCMLFP_01866 5e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFHCMLFP_01867 2.5e-245 hlyX S Transporter associated domain
HFHCMLFP_01868 4.1e-196 yueF S AI-2E family transporter
HFHCMLFP_01869 2.3e-72 S Acetyltransferase (GNAT) domain
HFHCMLFP_01870 8.9e-95
HFHCMLFP_01871 2.2e-104 ygaC J Belongs to the UPF0374 family
HFHCMLFP_01872 7.9e-143 recX 2.4.1.337 GT4 S Regulatory protein RecX
HFHCMLFP_01873 1.9e-144 frvR K transcriptional antiterminator
HFHCMLFP_01874 6.7e-133 frvR K transcriptional antiterminator
HFHCMLFP_01875 2.9e-63
HFHCMLFP_01876 6.1e-252 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFHCMLFP_01877 8.2e-79 F Nucleoside 2-deoxyribosyltransferase
HFHCMLFP_01878 1.8e-133 K UTRA
HFHCMLFP_01879 3.5e-290 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCMLFP_01880 2.7e-252 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCMLFP_01881 6.1e-85
HFHCMLFP_01882 2e-49 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HFHCMLFP_01883 6.9e-50 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFHCMLFP_01884 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HFHCMLFP_01885 4.5e-219 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HFHCMLFP_01886 3.2e-202 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
HFHCMLFP_01887 3.6e-208 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HFHCMLFP_01888 2.1e-48
HFHCMLFP_01889 1.3e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HFHCMLFP_01890 4.8e-102 V Restriction endonuclease
HFHCMLFP_01891 5.8e-157 5.1.3.3 G converts alpha-aldose to the beta-anomer
HFHCMLFP_01892 1.5e-211 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HFHCMLFP_01893 1e-102 S ECF transporter, substrate-specific component
HFHCMLFP_01895 7.3e-80 yodP 2.3.1.264 K Acetyltransferase GNAT Family
HFHCMLFP_01896 1.1e-85 ydcK S Belongs to the SprT family
HFHCMLFP_01897 7.3e-130 XK27_08845 S ABC transporter, ATP-binding protein
HFHCMLFP_01898 4.2e-140 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HFHCMLFP_01899 1.7e-155 XK27_08835 S ABC transporter
HFHCMLFP_01901 9e-72
HFHCMLFP_01902 0.0 pacL 3.6.3.8 P P-type ATPase
HFHCMLFP_01903 6e-216 V Beta-lactamase
HFHCMLFP_01904 2.1e-09 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFHCMLFP_01905 5.7e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFHCMLFP_01906 1.1e-217 V Beta-lactamase
HFHCMLFP_01907 7.2e-275 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFHCMLFP_01908 5e-125 gntR1 K UbiC transcription regulator-associated domain protein
HFHCMLFP_01909 2.6e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HFHCMLFP_01910 2.2e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFHCMLFP_01911 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
HFHCMLFP_01914 2e-157 yjjH S Calcineurin-like phosphoesterase
HFHCMLFP_01915 1.6e-266 dtpT U amino acid peptide transporter
HFHCMLFP_01916 0.0 macB_3 V ABC transporter, ATP-binding protein
HFHCMLFP_01917 1.1e-65
HFHCMLFP_01918 7.6e-76 S function, without similarity to other proteins
HFHCMLFP_01919 7.3e-264 G MFS/sugar transport protein
HFHCMLFP_01920 1.6e-229 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
HFHCMLFP_01921 5.4e-58
HFHCMLFP_01922 0.0 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
HFHCMLFP_01923 1.4e-17 S Virus attachment protein p12 family
HFHCMLFP_01924 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HFHCMLFP_01925 9.4e-70 feoA P FeoA
HFHCMLFP_01926 3.9e-123 E lipolytic protein G-D-S-L family
HFHCMLFP_01929 3e-116 ywnB S NAD(P)H-binding
HFHCMLFP_01930 1.3e-61 S MucBP domain
HFHCMLFP_01931 1.2e-62
HFHCMLFP_01933 6.6e-11
HFHCMLFP_01934 4e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
HFHCMLFP_01935 1.9e-68 S COG NOG38524 non supervised orthologous group
HFHCMLFP_01938 6.1e-35
HFHCMLFP_01939 8.6e-224 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFHCMLFP_01940 1.4e-303 frvR K Mga helix-turn-helix domain
HFHCMLFP_01941 1.5e-37 frvR K Mga helix-turn-helix domain
HFHCMLFP_01942 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_01943 1.2e-249 frvR K Mga helix-turn-helix domain
HFHCMLFP_01944 2.3e-265 lysP E amino acid
HFHCMLFP_01946 1.1e-130 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HFHCMLFP_01947 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HFHCMLFP_01948 1e-96
HFHCMLFP_01949 6.7e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
HFHCMLFP_01950 1.1e-192 S Protein of unknown function C-terminal (DUF3324)
HFHCMLFP_01951 1.2e-87
HFHCMLFP_01952 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HFHCMLFP_01953 2.6e-117 sodA 1.15.1.1 C Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HFHCMLFP_01954 3e-159 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HFHCMLFP_01955 8.9e-158 I alpha/beta hydrolase fold
HFHCMLFP_01956 3.6e-28
HFHCMLFP_01957 9.3e-74
HFHCMLFP_01958 4.7e-154 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HFHCMLFP_01959 2.5e-124 citR K FCD
HFHCMLFP_01960 6.9e-267 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
HFHCMLFP_01961 1.2e-92 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HFHCMLFP_01962 5.9e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HFHCMLFP_01963 9e-156 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HFHCMLFP_01964 1.3e-48 citD C Covalent carrier of the coenzyme of citrate lyase
HFHCMLFP_01965 3.3e-178 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HFHCMLFP_01967 1.8e-196 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
HFHCMLFP_01968 2.6e-41 gcdC 2.3.1.12 I Biotin-requiring enzyme
HFHCMLFP_01969 5.9e-52
HFHCMLFP_01970 1.1e-240 citM C Citrate transporter
HFHCMLFP_01971 2.8e-41
HFHCMLFP_01972 5.1e-104 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HFHCMLFP_01973 1.6e-88 K GNAT family
HFHCMLFP_01974 1e-105 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HFHCMLFP_01975 9.7e-58 K Transcriptional regulator PadR-like family
HFHCMLFP_01976 7.3e-131 ORF00048
HFHCMLFP_01977 6.2e-137 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HFHCMLFP_01978 1.5e-169 yjjC V ABC transporter
HFHCMLFP_01979 1.2e-291 M Exporter of polyketide antibiotics
HFHCMLFP_01980 4.7e-114 K Transcriptional regulator
HFHCMLFP_01981 1e-257 EGP Major facilitator Superfamily
HFHCMLFP_01982 1.8e-125 S membrane transporter protein
HFHCMLFP_01983 1.3e-156 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_01984 4e-161 S Alpha beta hydrolase
HFHCMLFP_01985 5.2e-60 yvoA_1 K Transcriptional regulator, GntR family
HFHCMLFP_01986 7.4e-124 skfE V ATPases associated with a variety of cellular activities
HFHCMLFP_01987 6.7e-19
HFHCMLFP_01988 1.2e-100 ydaF J Acetyltransferase (GNAT) domain
HFHCMLFP_01989 3e-159 oppF P Oligopeptide/dipeptide transporter, C-terminal region
HFHCMLFP_01990 9.6e-200 oppD P Oligopeptide/dipeptide transporter, C-terminal region
HFHCMLFP_01991 1.2e-22
HFHCMLFP_01992 3.6e-177 amiD EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFHCMLFP_01993 2.5e-167 oppB P Binding-protein-dependent transport system inner membrane component
HFHCMLFP_01994 1.5e-292 E Bacterial extracellular solute-binding proteins, family 5 Middle
HFHCMLFP_01995 1.8e-98 hchA S DJ-1/PfpI family
HFHCMLFP_01996 4.6e-52 K Transcriptional
HFHCMLFP_01997 8.2e-36
HFHCMLFP_01998 1e-264 V ABC transporter transmembrane region
HFHCMLFP_01999 3.4e-286 V ABC transporter transmembrane region
HFHCMLFP_02001 3.2e-68 S Iron-sulphur cluster biosynthesis
HFHCMLFP_02002 1.4e-15 2.7.1.39 S Phosphotransferase enzyme family
HFHCMLFP_02003 1.7e-258 lytN 3.5.1.104 M LysM domain
HFHCMLFP_02004 8.4e-134 zmp3 O Zinc-dependent metalloprotease
HFHCMLFP_02006 6.9e-128 repA K DeoR C terminal sensor domain
HFHCMLFP_02008 1e-48 lciIC K Helix-turn-helix XRE-family like proteins
HFHCMLFP_02009 3e-84 yjdB S Domain of unknown function (DUF4767)
HFHCMLFP_02010 1.3e-31 S Abortive infection C-terminus
HFHCMLFP_02012 2.8e-103 L reverse transcriptase
HFHCMLFP_02013 1.6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HFHCMLFP_02014 3e-178 coaA 2.7.1.33 F Pantothenic acid kinase
HFHCMLFP_02015 9.2e-14
HFHCMLFP_02016 7.9e-24
HFHCMLFP_02017 2.8e-276 pipD E Dipeptidase
HFHCMLFP_02018 5.2e-51 S Psort location Cytoplasmic, score
HFHCMLFP_02019 4.2e-83 ykhA 3.1.2.20 I Thioesterase superfamily
HFHCMLFP_02020 0.0 helD 3.6.4.12 L DNA helicase
HFHCMLFP_02022 1.4e-21
HFHCMLFP_02023 0.0 yjbQ P TrkA C-terminal domain protein
HFHCMLFP_02024 1.1e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HFHCMLFP_02025 8.5e-81 yjhE S Phage tail protein
HFHCMLFP_02026 8.2e-241 mntH P H( )-stimulated, divalent metal cation uptake system
HFHCMLFP_02027 5.4e-186 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HFHCMLFP_02028 3.5e-128 pgm3 G Phosphoglycerate mutase family
HFHCMLFP_02029 0.0 V FtsX-like permease family
HFHCMLFP_02030 2.6e-135 cysA V ABC transporter, ATP-binding protein
HFHCMLFP_02031 0.0 E amino acid
HFHCMLFP_02032 3.4e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HFHCMLFP_02033 2.1e-238 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFHCMLFP_02034 2.5e-154 nodB3 G Polysaccharide deacetylase
HFHCMLFP_02035 9.1e-104 M Peptidase_C39 like family
HFHCMLFP_02036 2.7e-57
HFHCMLFP_02037 5.7e-55 S Glucosyl transferase GtrII
HFHCMLFP_02038 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_02039 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_02040 1.8e-27 S Glucosyl transferase GtrII
HFHCMLFP_02041 2.4e-131 3.1.4.46 M Peptidase_C39 like family
HFHCMLFP_02042 2.9e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFHCMLFP_02043 1.1e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFHCMLFP_02044 3e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HFHCMLFP_02045 1.3e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFHCMLFP_02046 4.2e-137 M Glycosyl hydrolases family 25
HFHCMLFP_02047 2e-258 wcaJ M Bacterial sugar transferase
HFHCMLFP_02048 3.2e-175 cps2D 5.1.3.2 M RmlD substrate binding domain
HFHCMLFP_02049 4.8e-109 glnP P ABC transporter permease
HFHCMLFP_02050 4.6e-109 gluC P ABC transporter permease
HFHCMLFP_02051 3.8e-148 glnH ET ABC transporter substrate-binding protein
HFHCMLFP_02052 7.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFHCMLFP_02053 7.2e-178
HFHCMLFP_02055 6.1e-84 zur P Belongs to the Fur family
HFHCMLFP_02056 2.2e-09
HFHCMLFP_02057 1.3e-110 gmk2 2.7.4.8 F Guanylate kinase
HFHCMLFP_02058 2.5e-68 GnaT 2.5.1.16 K Acetyltransferase (GNAT) domain
HFHCMLFP_02059 1.9e-124 spl M NlpC/P60 family
HFHCMLFP_02060 1.2e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFHCMLFP_02061 3.3e-172 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFHCMLFP_02062 1e-54 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HFHCMLFP_02063 2.3e-173 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFHCMLFP_02064 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HFHCMLFP_02065 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HFHCMLFP_02066 8.9e-286 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HFHCMLFP_02067 9.4e-201 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HFHCMLFP_02068 3.6e-197 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HFHCMLFP_02069 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HFHCMLFP_02070 4.7e-204 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HFHCMLFP_02071 7.7e-102 ylcC 3.4.22.70 M Sortase family
HFHCMLFP_02072 1.4e-145 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFHCMLFP_02073 0.0 fbp 3.1.3.11 G phosphatase activity
HFHCMLFP_02074 2.6e-65 nrp 1.20.4.1 P ArsC family
HFHCMLFP_02075 0.0 clpL O associated with various cellular activities
HFHCMLFP_02076 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFHCMLFP_02077 1.1e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFHCMLFP_02078 3e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HFHCMLFP_02079 1.3e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFHCMLFP_02080 1.1e-144 ywqE 3.1.3.48 GM PHP domain protein
HFHCMLFP_02081 5.2e-151 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFHCMLFP_02082 3.1e-13 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFHCMLFP_02083 4e-209 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFHCMLFP_02084 8.3e-77 cpsE M Bacterial sugar transferase
HFHCMLFP_02085 1.5e-31 rgpB GT2 M Glycosyltransferase, group 2 family protein
HFHCMLFP_02086 5.6e-21 S O-antigen ligase like membrane protein
HFHCMLFP_02087 1.2e-146 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HFHCMLFP_02088 1.3e-44 cps1B GT2,GT4 M Glycosyl transferases group 1
HFHCMLFP_02089 1.7e-50 S Glycosyl transferase family 2
HFHCMLFP_02090 3.9e-68 licD M LicD family
HFHCMLFP_02091 1.7e-35 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HFHCMLFP_02092 2e-63 MA20_43635 M Capsular polysaccharide synthesis protein
HFHCMLFP_02093 9.5e-153 rgpAc GT4 M Domain of unknown function (DUF1972)
HFHCMLFP_02094 1.1e-28 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HFHCMLFP_02095 5.7e-61 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HFHCMLFP_02096 9.8e-121 epsB M biosynthesis protein
HFHCMLFP_02097 1.3e-131 E lipolytic protein G-D-S-L family
HFHCMLFP_02098 1.4e-81 ccl S QueT transporter
HFHCMLFP_02099 2.3e-125 IQ Enoyl-(Acyl carrier protein) reductase
HFHCMLFP_02100 3.7e-37 XK27_01315 S Protein of unknown function (DUF2829)
HFHCMLFP_02101 1.9e-47 K sequence-specific DNA binding
HFHCMLFP_02102 7.3e-115 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
HFHCMLFP_02103 1.3e-179 oppF P Belongs to the ABC transporter superfamily
HFHCMLFP_02104 1.1e-197 oppD P Belongs to the ABC transporter superfamily
HFHCMLFP_02105 2.5e-178 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFHCMLFP_02106 8e-163 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFHCMLFP_02107 1.5e-302 oppA E ABC transporter, substratebinding protein
HFHCMLFP_02108 1.4e-251 EGP Major facilitator Superfamily
HFHCMLFP_02109 1.3e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFHCMLFP_02110 9.5e-132 yrjD S LUD domain
HFHCMLFP_02111 3.4e-288 lutB C 4Fe-4S dicluster domain
HFHCMLFP_02112 3.3e-149 lutA C Cysteine-rich domain
HFHCMLFP_02113 4.5e-84
HFHCMLFP_02114 1.5e-50 chbA 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
HFHCMLFP_02115 1.6e-210 S Bacterial protein of unknown function (DUF871)
HFHCMLFP_02116 6.7e-69 S Domain of unknown function (DUF3284)
HFHCMLFP_02117 4.8e-07
HFHCMLFP_02118 2.9e-265 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCMLFP_02119 0.0 rafA 3.2.1.22 G alpha-galactosidase
HFHCMLFP_02120 4.8e-134 S Belongs to the UPF0246 family
HFHCMLFP_02121 4.4e-135 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
HFHCMLFP_02122 0.0 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
HFHCMLFP_02123 3.4e-149 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
HFHCMLFP_02124 4.1e-80
HFHCMLFP_02125 1.1e-59 S WxL domain surface cell wall-binding
HFHCMLFP_02126 2.3e-145 frlD 2.7.1.218 G pfkB family carbohydrate kinase
HFHCMLFP_02127 2.4e-284 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
HFHCMLFP_02128 3.2e-203 S Protein of unknown function (DUF917)
HFHCMLFP_02129 5.7e-212 F Permease for cytosine/purines, uracil, thiamine, allantoin
HFHCMLFP_02130 1.6e-138
HFHCMLFP_02131 7.2e-152 S Protein of unknown function (DUF1524)
HFHCMLFP_02132 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_02133 4.6e-231 S Protein of unknown function (DUF1524)
HFHCMLFP_02134 1.5e-73 3.1.21.3 V Type I restriction modification DNA specificity domain
HFHCMLFP_02135 3.8e-173 L Belongs to the 'phage' integrase family
HFHCMLFP_02136 4.7e-86 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
HFHCMLFP_02137 1.2e-217 hsdM 2.1.1.72 V type I restriction-modification system
HFHCMLFP_02138 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HFHCMLFP_02139 8.2e-131 3.1.11.5 L Viral (Superfamily 1) RNA helicase
HFHCMLFP_02140 4.1e-212 ykiI
HFHCMLFP_02141 0.0 scrA 2.7.1.211 G phosphotransferase system
HFHCMLFP_02142 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HFHCMLFP_02143 9.2e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HFHCMLFP_02144 5.7e-304 scrB 3.2.1.26 GH32 G invertase
HFHCMLFP_02145 5.3e-164 azoB GM NmrA-like family
HFHCMLFP_02146 1.7e-234 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HFHCMLFP_02147 7.7e-143 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HFHCMLFP_02148 6.2e-151 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFHCMLFP_02149 7.4e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HFHCMLFP_02150 3.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFHCMLFP_02151 1.7e-62 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFHCMLFP_02152 2.4e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFHCMLFP_02153 4.7e-126 IQ reductase
HFHCMLFP_02154 1.5e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HFHCMLFP_02155 8.2e-174 fabK 1.3.1.9 S Nitronate monooxygenase
HFHCMLFP_02156 1.2e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFHCMLFP_02157 5.9e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFHCMLFP_02158 6.2e-76 marR K Winged helix DNA-binding domain
HFHCMLFP_02159 3.1e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HFHCMLFP_02160 4.6e-193 bioH 2.1.1.197, 3.1.1.85, 3.7.1.13, 3.7.1.9, 4.2.99.20 E Alpha/beta hydrolase family
HFHCMLFP_02161 5.9e-227 bdhA C Iron-containing alcohol dehydrogenase
HFHCMLFP_02162 6.6e-237 L Transposase
HFHCMLFP_02163 3.6e-48 S Uncharacterized protein conserved in bacteria (DUF2316)
HFHCMLFP_02164 1.8e-66 K MarR family
HFHCMLFP_02165 1.3e-12 S response to antibiotic
HFHCMLFP_02166 3.5e-164 S Putative esterase
HFHCMLFP_02167 5.3e-198
HFHCMLFP_02168 2.7e-103 rmaB K Transcriptional regulator, MarR family
HFHCMLFP_02169 0.0 lmrA 3.6.3.44 V ABC transporter
HFHCMLFP_02170 8.4e-84 F NUDIX domain
HFHCMLFP_02171 3.9e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFHCMLFP_02172 3.4e-21
HFHCMLFP_02173 2.9e-116 S zinc-ribbon domain
HFHCMLFP_02174 5e-204 pbpX1 V Beta-lactamase
HFHCMLFP_02175 1.7e-185 K AI-2E family transporter
HFHCMLFP_02176 1.3e-128 srtA 3.4.22.70 M Sortase family
HFHCMLFP_02177 7.6e-65 gtcA S Teichoic acid glycosylation protein
HFHCMLFP_02178 1.9e-175 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HFHCMLFP_02179 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HFHCMLFP_02180 4e-167 gbuC E glycine betaine
HFHCMLFP_02181 1.1e-147 proW E glycine betaine
HFHCMLFP_02182 2.2e-221 gbuA 3.6.3.32 E glycine betaine
HFHCMLFP_02183 9.2e-138 sfsA S Belongs to the SfsA family
HFHCMLFP_02184 1.8e-67 usp1 T Universal stress protein family
HFHCMLFP_02185 3.3e-252 yxbA 6.3.1.12 S ATP-grasp enzyme
HFHCMLFP_02186 7.7e-131 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFHCMLFP_02187 5.5e-286 thrC 4.2.3.1 E Threonine synthase
HFHCMLFP_02188 1.1e-228 hom 1.1.1.3 E homoserine dehydrogenase
HFHCMLFP_02189 1.3e-251 yclM 2.7.2.4 E Belongs to the aspartokinase family
HFHCMLFP_02190 6.6e-237 L Transposase
HFHCMLFP_02191 1.1e-166 yqiK S SPFH domain / Band 7 family
HFHCMLFP_02192 2.3e-39
HFHCMLFP_02193 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_02194 9.6e-173 pfoS S Phosphotransferase system, EIIC
HFHCMLFP_02195 5.5e-178 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFHCMLFP_02196 2.4e-217 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HFHCMLFP_02197 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_02198 3.3e-124 WQ51_05710 S Mitochondrial biogenesis AIM24
HFHCMLFP_02199 2.8e-68 K Bacterial regulatory proteins, tetR family
HFHCMLFP_02200 1.7e-122 XK27_06930 V domain protein
HFHCMLFP_02201 2.3e-115 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFHCMLFP_02202 1.8e-68 FG Scavenger mRNA decapping enzyme C-term binding
HFHCMLFP_02203 0.0 asnB 6.3.5.4 E Asparagine synthase
HFHCMLFP_02205 3.1e-137 mprF 2.3.2.3 M lysyltransferase activity
HFHCMLFP_02207 6.3e-204 S Calcineurin-like phosphoesterase
HFHCMLFP_02208 2e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HFHCMLFP_02209 1e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFHCMLFP_02210 6.4e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFHCMLFP_02211 4.8e-165 natA S abc transporter atp-binding protein
HFHCMLFP_02212 1.4e-218 ysdA CP ABC-2 family transporter protein
HFHCMLFP_02213 9.6e-65 K helix_turn_helix gluconate operon transcriptional repressor
HFHCMLFP_02214 7.5e-163 CcmA V ABC transporter
HFHCMLFP_02215 1e-111 I ABC-2 family transporter protein
HFHCMLFP_02216 8.9e-147 IQ reductase
HFHCMLFP_02217 9e-201 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HFHCMLFP_02218 2.2e-185 tdcB 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HFHCMLFP_02219 6.7e-297 S OPT oligopeptide transporter protein
HFHCMLFP_02220 1.5e-61 S Coenzyme PQQ synthesis protein D (PqqD)
HFHCMLFP_02221 2.3e-281 pipD E Dipeptidase
HFHCMLFP_02222 5.2e-256 gor 1.8.1.7 C Glutathione reductase
HFHCMLFP_02223 4.3e-248 lmrB EGP Major facilitator Superfamily
HFHCMLFP_02224 3.6e-97 yxaF K Bacterial regulatory proteins, tetR family
HFHCMLFP_02225 4.7e-295 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCMLFP_02226 0.0 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFHCMLFP_02227 2.8e-154 licT K CAT RNA binding domain
HFHCMLFP_02228 1.8e-290 cydC V ABC transporter transmembrane region
HFHCMLFP_02229 0.0 cydD CO ABC transporter transmembrane region
HFHCMLFP_02230 4.6e-73 S NusG domain II
HFHCMLFP_02231 9.6e-155 M Peptidoglycan-binding domain 1 protein
HFHCMLFP_02232 1.1e-40 P Cadmium resistance transporter
HFHCMLFP_02233 3.9e-106 S CRISPR-associated protein (Cas_Csn2)
HFHCMLFP_02234 3.1e-45 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFHCMLFP_02235 8.7e-90 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFHCMLFP_02236 2.4e-60 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFHCMLFP_02237 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HFHCMLFP_02238 1.9e-141
HFHCMLFP_02239 5.9e-216 ywhK S Membrane
HFHCMLFP_02240 3.8e-63 S Protein of unknown function (DUF1093)
HFHCMLFP_02241 4.2e-50 yvlA
HFHCMLFP_02242 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HFHCMLFP_02243 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HFHCMLFP_02244 1.3e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HFHCMLFP_02245 6.8e-278 cydA 1.10.3.14 C ubiquinol oxidase
HFHCMLFP_02247 9.1e-237 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HFHCMLFP_02248 5.5e-189 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HFHCMLFP_02249 9.3e-16
HFHCMLFP_02250 1.6e-85
HFHCMLFP_02251 8e-24
HFHCMLFP_02252 7e-167 yicL EG EamA-like transporter family
HFHCMLFP_02253 1.5e-112 tag 3.2.2.20 L glycosylase
HFHCMLFP_02254 5e-78 usp5 T universal stress protein
HFHCMLFP_02255 1.8e-55 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_02256 2.9e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
HFHCMLFP_02257 1.2e-224 queG 1.17.99.6 C Domain of unknown function (DUF1730)
HFHCMLFP_02258 1.7e-63
HFHCMLFP_02259 7.1e-87 bioY S BioY family
HFHCMLFP_02260 3.5e-70 adhR K helix_turn_helix, mercury resistance
HFHCMLFP_02261 1.7e-79 C Flavodoxin
HFHCMLFP_02262 3.5e-193 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HFHCMLFP_02263 2.2e-114 GM NmrA-like family
HFHCMLFP_02265 4e-101 Q methyltransferase
HFHCMLFP_02266 3.4e-93 T Sh3 type 3 domain protein
HFHCMLFP_02267 1.8e-118 yfeJ 6.3.5.2 F glutamine amidotransferase
HFHCMLFP_02268 1.1e-133 S Uncharacterized protein conserved in bacteria (DUF2263)
HFHCMLFP_02269 5.3e-259 yhdP S Transporter associated domain
HFHCMLFP_02270 2.1e-258 lmrB EGP Major facilitator Superfamily
HFHCMLFP_02271 1.6e-61 S Domain of unknown function (DUF4811)
HFHCMLFP_02272 3.8e-99 maf D nucleoside-triphosphate diphosphatase activity
HFHCMLFP_02273 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFHCMLFP_02274 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFHCMLFP_02275 0.0 ydaO E amino acid
HFHCMLFP_02276 3.6e-56 S Domain of unknown function (DUF1827)
HFHCMLFP_02277 3.8e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFHCMLFP_02278 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFHCMLFP_02279 1.1e-110 S CAAX protease self-immunity
HFHCMLFP_02280 8.2e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFHCMLFP_02281 1.1e-184
HFHCMLFP_02282 1.1e-158 ytrB V ABC transporter
HFHCMLFP_02283 2.7e-61 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HFHCMLFP_02284 7.2e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFHCMLFP_02285 0.0 uup S ABC transporter, ATP-binding protein
HFHCMLFP_02286 3.9e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFHCMLFP_02287 4.2e-189 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFHCMLFP_02288 2.1e-99 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HFHCMLFP_02289 5.3e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HFHCMLFP_02290 1e-73
HFHCMLFP_02291 3.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HFHCMLFP_02292 2e-180 ansA 3.5.1.1 EJ Asparaginase
HFHCMLFP_02293 3.9e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
HFHCMLFP_02294 4.5e-144 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFHCMLFP_02295 2.2e-57 yabA L Involved in initiation control of chromosome replication
HFHCMLFP_02296 5.3e-173 holB 2.7.7.7 L DNA polymerase III
HFHCMLFP_02297 4.6e-52 yaaQ S Cyclic-di-AMP receptor
HFHCMLFP_02298 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFHCMLFP_02299 5.8e-34 S Protein of unknown function (DUF2508)
HFHCMLFP_02300 1.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFHCMLFP_02301 8.4e-32 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFHCMLFP_02302 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFHCMLFP_02303 3.8e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFHCMLFP_02304 5.6e-50
HFHCMLFP_02305 2.2e-105 rsmC 2.1.1.172 J Methyltransferase
HFHCMLFP_02306 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFHCMLFP_02307 2e-44
HFHCMLFP_02308 2.2e-176 ccpB 5.1.1.1 K lacI family
HFHCMLFP_02309 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
HFHCMLFP_02310 9.9e-158 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFHCMLFP_02311 1.1e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFHCMLFP_02312 6.5e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFHCMLFP_02313 3e-221 mdtG EGP Major facilitator Superfamily
HFHCMLFP_02314 4.7e-154 K acetyltransferase
HFHCMLFP_02315 6.2e-67
HFHCMLFP_02316 3e-218 yceI G Sugar (and other) transporter
HFHCMLFP_02317 4.2e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HFHCMLFP_02318 1.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFHCMLFP_02319 8.2e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFHCMLFP_02320 0.0 mgtA 3.6.3.2, 3.6.3.6 P COG0474 Cation transport ATPase
HFHCMLFP_02321 6.5e-268 nylA 3.5.1.4 J Belongs to the amidase family
HFHCMLFP_02322 2.1e-66 frataxin S Domain of unknown function (DU1801)
HFHCMLFP_02323 1.2e-91 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
HFHCMLFP_02324 4e-96 S ECF transporter, substrate-specific component
HFHCMLFP_02325 2e-62 S Domain of unknown function (DUF4430)
HFHCMLFP_02326 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HFHCMLFP_02327 5e-78 F Nucleoside 2-deoxyribosyltransferase
HFHCMLFP_02328 5.8e-160 S Alpha/beta hydrolase of unknown function (DUF915)
HFHCMLFP_02329 3.4e-100 nusG K Participates in transcription elongation, termination and antitermination
HFHCMLFP_02330 5.7e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFHCMLFP_02331 1.5e-155 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HFHCMLFP_02332 2.6e-169 menA 2.5.1.74 M UbiA prenyltransferase family
HFHCMLFP_02333 4e-198 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFHCMLFP_02334 2.6e-137 cad S FMN_bind
HFHCMLFP_02335 0.0 ndh 1.6.99.3 C NADH dehydrogenase
HFHCMLFP_02336 3.1e-80 ynhH S NusG domain II
HFHCMLFP_02337 1.2e-98 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HFHCMLFP_02338 9.3e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFHCMLFP_02340 3e-122 1.5.1.40 S Rossmann-like domain
HFHCMLFP_02341 2.6e-189 XK27_00915 C Luciferase-like monooxygenase
HFHCMLFP_02342 2.1e-120 V ATPases associated with a variety of cellular activities
HFHCMLFP_02343 3e-173
HFHCMLFP_02344 9.7e-147
HFHCMLFP_02345 1.3e-97 T Calcineurin-like phosphoesterase superfamily domain
HFHCMLFP_02347 2.4e-98 yacP S YacP-like NYN domain
HFHCMLFP_02348 3.3e-141 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFHCMLFP_02349 5.5e-74 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFHCMLFP_02350 9.3e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFHCMLFP_02351 4.3e-261 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HFHCMLFP_02352 3e-107
HFHCMLFP_02354 5.3e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFHCMLFP_02355 1.1e-186 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HFHCMLFP_02356 5.7e-118 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HFHCMLFP_02357 9.1e-142 K SIS domain
HFHCMLFP_02358 2e-112 yhfC S Putative membrane peptidase family (DUF2324)
HFHCMLFP_02359 4.1e-176 S Membrane
HFHCMLFP_02360 8e-61 K helix_turn_helix gluconate operon transcriptional repressor
HFHCMLFP_02361 6.4e-219 inlJ M MucBP domain
HFHCMLFP_02362 3e-131 S ABC-2 family transporter protein
HFHCMLFP_02363 1.3e-157 V ABC transporter, ATP-binding protein
HFHCMLFP_02364 3.3e-203 yacL S domain protein
HFHCMLFP_02365 1.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFHCMLFP_02366 4.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
HFHCMLFP_02367 9.9e-51 HA62_12640 S GCN5-related N-acetyl-transferase
HFHCMLFP_02368 9.5e-70 S Protein of unknown function (DUF805)
HFHCMLFP_02369 3.6e-257 pepC 3.4.22.40 E aminopeptidase
HFHCMLFP_02370 9.3e-261 pepC 3.4.22.40 E Peptidase C1-like family
HFHCMLFP_02371 5.7e-200
HFHCMLFP_02372 7e-220 S ABC-2 family transporter protein
HFHCMLFP_02373 5.1e-167 V ATPases associated with a variety of cellular activities
HFHCMLFP_02374 0.0 kup P Transport of potassium into the cell
HFHCMLFP_02375 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
HFHCMLFP_02376 1.1e-104 ccpN K Domain in cystathionine beta-synthase and other proteins.
HFHCMLFP_02377 7.7e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFHCMLFP_02378 1.1e-206 ltrA S Bacterial low temperature requirement A protein (LtrA)
HFHCMLFP_02379 7.2e-46
HFHCMLFP_02380 4.9e-207 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HFHCMLFP_02381 6.6e-237 L Transposase
HFHCMLFP_02382 1e-09 yhjA K CsbD-like
HFHCMLFP_02383 7e-08
HFHCMLFP_02384 1.9e-32
HFHCMLFP_02385 1.3e-38
HFHCMLFP_02386 3.7e-224 pimH EGP Major facilitator Superfamily
HFHCMLFP_02387 2.4e-202 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFHCMLFP_02388 3.3e-147 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFHCMLFP_02390 3.1e-42
HFHCMLFP_02391 1.8e-231 ywhK S Membrane
HFHCMLFP_02392 1.9e-147 3.4.22.70 M Sortase family
HFHCMLFP_02393 2.6e-299 M Cna protein B-type domain
HFHCMLFP_02394 8e-241
HFHCMLFP_02395 0.0 M domain protein
HFHCMLFP_02396 1.9e-103
HFHCMLFP_02397 4e-231 N Uncharacterized conserved protein (DUF2075)
HFHCMLFP_02398 1e-206 MA20_36090 S Protein of unknown function (DUF2974)
HFHCMLFP_02399 1.2e-77 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_02400 2.2e-54 K Transcriptional regulator PadR-like family
HFHCMLFP_02401 3.4e-20
HFHCMLFP_02402 2e-24
HFHCMLFP_02403 1.3e-137
HFHCMLFP_02404 5.4e-46 S Enterocin A Immunity
HFHCMLFP_02405 1.4e-44 S Enterocin A Immunity
HFHCMLFP_02406 1.1e-44 spiA K TRANSCRIPTIONal
HFHCMLFP_02407 1.5e-250 yjjP S Putative threonine/serine exporter
HFHCMLFP_02409 1e-53
HFHCMLFP_02410 6.7e-222 mesE M Transport protein ComB
HFHCMLFP_02411 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HFHCMLFP_02414 1.5e-134 2.7.13.3 T protein histidine kinase activity
HFHCMLFP_02415 9.5e-144 plnD K LytTr DNA-binding domain
HFHCMLFP_02417 7e-10
HFHCMLFP_02421 7.5e-141 S CAAX protease self-immunity
HFHCMLFP_02423 6.8e-56
HFHCMLFP_02425 8.4e-54 S Enterocin A Immunity
HFHCMLFP_02426 1.7e-102 yncA 2.3.1.79 S Maltose acetyltransferase
HFHCMLFP_02427 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_02431 3e-181 S Aldo keto reductase
HFHCMLFP_02432 2.7e-121 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HFHCMLFP_02433 1.6e-216 yqiG C Oxidoreductase
HFHCMLFP_02434 1.9e-253 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFHCMLFP_02435 6.4e-134
HFHCMLFP_02436 4.5e-20
HFHCMLFP_02437 1.3e-261 mntH P H( )-stimulated, divalent metal cation uptake system
HFHCMLFP_02438 0.0 pacL P P-type ATPase
HFHCMLFP_02439 2.2e-55
HFHCMLFP_02440 9.2e-240 EGP Major Facilitator Superfamily
HFHCMLFP_02441 0.0 mco Q Multicopper oxidase
HFHCMLFP_02442 1.2e-25
HFHCMLFP_02443 8.4e-111 2.5.1.105 P Cation efflux family
HFHCMLFP_02444 5.4e-53 czrA K Transcriptional regulator, ArsR family
HFHCMLFP_02445 7.6e-177 sitA P Belongs to the bacterial solute-binding protein 9 family
HFHCMLFP_02446 3.6e-144 mtsB U ABC 3 transport family
HFHCMLFP_02447 3.4e-132 mntB 3.6.3.35 P AAA domain, putative AbiEii toxin, Type IV TA system
HFHCMLFP_02448 3.2e-275 aldA 1.2.1.21, 1.2.1.22 C Belongs to the aldehyde dehydrogenase family
HFHCMLFP_02449 5e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFHCMLFP_02450 3.4e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
HFHCMLFP_02451 1.6e-117 GM NmrA-like family
HFHCMLFP_02452 1.5e-112 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HFHCMLFP_02453 1.2e-70
HFHCMLFP_02454 4.5e-250 M domain protein
HFHCMLFP_02455 1.9e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
HFHCMLFP_02456 1.8e-19
HFHCMLFP_02457 1.9e-41
HFHCMLFP_02458 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_02459 3.4e-13
HFHCMLFP_02462 2.4e-51 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFHCMLFP_02463 1.9e-68 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFHCMLFP_02465 4e-221 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFHCMLFP_02466 6.4e-230 3.6.3.6 P Cation transporter/ATPase, N-terminus
HFHCMLFP_02467 2.3e-157 phnD P Phosphonate ABC transporter
HFHCMLFP_02468 7.5e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HFHCMLFP_02469 7.8e-135 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HFHCMLFP_02470 5e-145 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HFHCMLFP_02471 1.1e-173 ssuA P NMT1-like family
HFHCMLFP_02472 6.8e-292 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
HFHCMLFP_02473 1.1e-231 yfiQ I Acyltransferase family
HFHCMLFP_02474 1.2e-115 ssuB P ATPases associated with a variety of cellular activities
HFHCMLFP_02475 3.2e-147 ssuC U Binding-protein-dependent transport system inner membrane component
HFHCMLFP_02476 2.5e-133 S ABC-2 family transporter protein
HFHCMLFP_02477 1.2e-132 S ABC-2 family transporter protein
HFHCMLFP_02478 1.2e-132 S ABC transporter
HFHCMLFP_02479 1.1e-82
HFHCMLFP_02480 5.6e-55
HFHCMLFP_02481 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HFHCMLFP_02482 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFHCMLFP_02483 6e-106 K Bacterial regulatory proteins, tetR family
HFHCMLFP_02484 1.7e-185 yxeA V FtsX-like permease family
HFHCMLFP_02485 2.9e-128 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
HFHCMLFP_02486 1.1e-33
HFHCMLFP_02487 5.3e-112 tipA K TipAS antibiotic-recognition domain
HFHCMLFP_02488 1.8e-20 M1-1017
HFHCMLFP_02489 8.2e-33 K Transcriptional regulator PadR-like family
HFHCMLFP_02490 1.4e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFHCMLFP_02491 8.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFHCMLFP_02492 1e-156 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFHCMLFP_02493 1.6e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFHCMLFP_02494 4.5e-115
HFHCMLFP_02495 4.8e-61 rplQ J Ribosomal protein L17
HFHCMLFP_02496 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFHCMLFP_02497 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFHCMLFP_02498 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFHCMLFP_02499 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HFHCMLFP_02500 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFHCMLFP_02501 1.6e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFHCMLFP_02502 1.5e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFHCMLFP_02503 6.5e-62 rplO J Binds to the 23S rRNA
HFHCMLFP_02504 3.9e-24 rpmD J Ribosomal protein L30
HFHCMLFP_02505 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFHCMLFP_02506 1.8e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFHCMLFP_02507 1.7e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFHCMLFP_02508 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFHCMLFP_02509 8.5e-96 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFHCMLFP_02510 1.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFHCMLFP_02511 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFHCMLFP_02512 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFHCMLFP_02513 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HFHCMLFP_02514 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFHCMLFP_02515 6.2e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFHCMLFP_02516 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFHCMLFP_02517 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFHCMLFP_02518 2.9e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFHCMLFP_02519 2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFHCMLFP_02520 1.7e-108 rplD J Forms part of the polypeptide exit tunnel
HFHCMLFP_02521 4e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFHCMLFP_02522 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HFHCMLFP_02523 1.6e-68 psiE S Phosphate-starvation-inducible E
HFHCMLFP_02524 5.5e-106 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HFHCMLFP_02525 3.5e-199 yfjR K WYL domain
HFHCMLFP_02526 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFHCMLFP_02527 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFHCMLFP_02528 1.2e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFHCMLFP_02529 0.0 M domain protein
HFHCMLFP_02530 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_02531 5.2e-20 3.4.23.43
HFHCMLFP_02532 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFHCMLFP_02533 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFHCMLFP_02534 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFHCMLFP_02535 4.3e-80 ctsR K Belongs to the CtsR family
HFHCMLFP_02544 4e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
HFHCMLFP_02545 1.9e-68 S COG NOG38524 non supervised orthologous group
HFHCMLFP_02548 6.1e-35
HFHCMLFP_02549 6.6e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HFHCMLFP_02550 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFHCMLFP_02551 1.7e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFHCMLFP_02552 5.1e-162 S WxL domain surface cell wall-binding
HFHCMLFP_02553 1.3e-185 S Bacterial protein of unknown function (DUF916)
HFHCMLFP_02554 4e-195 S Protein of unknown function C-terminal (DUF3324)
HFHCMLFP_02555 0.0 S Leucine-rich repeat (LRR) protein
HFHCMLFP_02556 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFHCMLFP_02557 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HFHCMLFP_02558 3.9e-240 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFHCMLFP_02559 9.3e-70 yabR J RNA binding
HFHCMLFP_02560 1.1e-66 divIC D cell cycle
HFHCMLFP_02561 2.7e-39 yabO J S4 domain protein
HFHCMLFP_02562 2.5e-281 yabM S Polysaccharide biosynthesis protein
HFHCMLFP_02563 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFHCMLFP_02564 3.6e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFHCMLFP_02565 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HFHCMLFP_02566 1.5e-261 S Putative peptidoglycan binding domain
HFHCMLFP_02567 2.3e-119 S (CBS) domain
HFHCMLFP_02568 4e-122 yciB M ErfK YbiS YcfS YnhG
HFHCMLFP_02569 5.8e-285 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HFHCMLFP_02570 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
HFHCMLFP_02571 4.5e-86 S QueT transporter
HFHCMLFP_02572 5.6e-62 ndoA L Toxic component of a toxin-antitoxin (TA) module
HFHCMLFP_02573 5.2e-32
HFHCMLFP_02574 3.1e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFHCMLFP_02575 8.5e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFHCMLFP_02576 7e-265 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFHCMLFP_02578 1.3e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFHCMLFP_02579 1.1e-144
HFHCMLFP_02580 9.6e-123 S Tetratricopeptide repeat
HFHCMLFP_02581 3.7e-125
HFHCMLFP_02582 1.2e-65
HFHCMLFP_02583 2.5e-42 rpmE2 J Ribosomal protein L31
HFHCMLFP_02584 1.6e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFHCMLFP_02585 2.2e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFHCMLFP_02586 1.3e-157 S Protein of unknown function (DUF1211)
HFHCMLFP_02587 4.5e-54 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFHCMLFP_02588 1e-78 ywiB S Domain of unknown function (DUF1934)
HFHCMLFP_02589 4.3e-155 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HFHCMLFP_02590 7.1e-269 ywfO S HD domain protein
HFHCMLFP_02591 1.4e-80 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
HFHCMLFP_02592 7.5e-181 S DUF218 domain
HFHCMLFP_02593 7.9e-53 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFHCMLFP_02594 3.8e-79 E glutamate:sodium symporter activity
HFHCMLFP_02595 1.3e-54 nudA S ASCH
HFHCMLFP_02596 1.3e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFHCMLFP_02597 2.9e-217 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFHCMLFP_02598 4e-223 ysaA V RDD family
HFHCMLFP_02599 1e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HFHCMLFP_02600 2.9e-119 ybbL S ABC transporter, ATP-binding protein
HFHCMLFP_02601 9e-120 ybbM S Uncharacterised protein family (UPF0014)
HFHCMLFP_02602 1.3e-159 czcD P cation diffusion facilitator family transporter
HFHCMLFP_02603 6.7e-181 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFHCMLFP_02604 1.1e-37 veg S Biofilm formation stimulator VEG
HFHCMLFP_02605 2e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFHCMLFP_02606 1.3e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFHCMLFP_02607 3.6e-148 tatD L hydrolase, TatD family
HFHCMLFP_02608 2.6e-80 manR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HFHCMLFP_02609 1.5e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HFHCMLFP_02610 1.9e-169 yqhA G Aldose 1-epimerase
HFHCMLFP_02611 3.1e-122 T LytTr DNA-binding domain
HFHCMLFP_02612 8.5e-141 2.7.13.3 T GHKL domain
HFHCMLFP_02613 0.0 V ABC transporter
HFHCMLFP_02614 0.0 V ABC transporter
HFHCMLFP_02615 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFHCMLFP_02616 4.3e-174 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HFHCMLFP_02617 2.5e-152 yunF F Protein of unknown function DUF72
HFHCMLFP_02618 1.1e-91 3.6.1.55 F NUDIX domain
HFHCMLFP_02619 3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HFHCMLFP_02620 1.6e-106 yiiE S Protein of unknown function (DUF1211)
HFHCMLFP_02621 1.4e-127 cobB K Sir2 family
HFHCMLFP_02622 1.4e-16
HFHCMLFP_02623 4.2e-172
HFHCMLFP_02624 2.1e-96 yxkA S Phosphatidylethanolamine-binding protein
HFHCMLFP_02625 1.6e-18
HFHCMLFP_02626 2.4e-149 ypuA S Protein of unknown function (DUF1002)
HFHCMLFP_02627 2.7e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HFHCMLFP_02628 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HFHCMLFP_02629 1.2e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HFHCMLFP_02630 8.3e-176 S Aldo keto reductase
HFHCMLFP_02631 6.1e-154 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HFHCMLFP_02632 4e-92 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HFHCMLFP_02633 6.3e-241 dinF V MatE
HFHCMLFP_02634 1.9e-110 S TPM domain
HFHCMLFP_02635 1e-102 lemA S LemA family
HFHCMLFP_02636 1.6e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFHCMLFP_02637 1.3e-251 gshR 1.8.1.7 C Glutathione reductase
HFHCMLFP_02638 1.3e-176 proV E ABC transporter, ATP-binding protein
HFHCMLFP_02639 3.4e-275 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFHCMLFP_02641 0.0 helD 3.6.4.12 L DNA helicase
HFHCMLFP_02642 3.5e-149 rlrG K Transcriptional regulator
HFHCMLFP_02643 2.2e-171 shetA P Voltage-dependent anion channel
HFHCMLFP_02644 3.4e-112 S CAAX protease self-immunity
HFHCMLFP_02646 3.8e-114 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFHCMLFP_02647 3e-69 K MarR family
HFHCMLFP_02648 0.0 uvrA3 L excinuclease ABC
HFHCMLFP_02649 1.1e-192 yghZ C Aldo keto reductase family protein
HFHCMLFP_02650 3e-145 S hydrolase
HFHCMLFP_02651 3.1e-59
HFHCMLFP_02652 4.1e-11
HFHCMLFP_02653 3e-106 yoaK S Protein of unknown function (DUF1275)
HFHCMLFP_02654 1.4e-124 yjhF G Phosphoglycerate mutase family
HFHCMLFP_02655 3e-153 yitU 3.1.3.104 S hydrolase
HFHCMLFP_02656 2.6e-88 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFHCMLFP_02657 1.7e-165 K LysR substrate binding domain
HFHCMLFP_02658 3.5e-227 EK Aminotransferase, class I
HFHCMLFP_02659 4.9e-181 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFHCMLFP_02660 2.7e-118 ydfK S Protein of unknown function (DUF554)
HFHCMLFP_02661 2.3e-89
HFHCMLFP_02662 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFHCMLFP_02663 3.3e-172 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HFHCMLFP_02664 8e-129 rpl K Helix-turn-helix domain, rpiR family
HFHCMLFP_02665 3.6e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFHCMLFP_02666 1.5e-135 K UTRA domain
HFHCMLFP_02667 2.8e-251 fucA 3.2.1.51 GH29 G Alpha-L-fucosidase
HFHCMLFP_02668 1.3e-163 2.7.1.191 G PTS system sorbose subfamily IIB component
HFHCMLFP_02669 9.5e-128 G PTS system sorbose-specific iic component
HFHCMLFP_02670 5.3e-150 G PTS system mannose/fructose/sorbose family IID component
HFHCMLFP_02671 9.5e-47 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HFHCMLFP_02672 1.2e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFHCMLFP_02673 6.6e-289 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFHCMLFP_02674 5.4e-153 ypbG 2.7.1.2 GK ROK family
HFHCMLFP_02675 2.8e-238 S Metal-independent alpha-mannosidase (GH125)
HFHCMLFP_02676 0.0 mngB 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HFHCMLFP_02677 1.5e-239 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCMLFP_02678 7.2e-135 K UbiC transcription regulator-associated domain protein
HFHCMLFP_02679 1e-136 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HFHCMLFP_02681 2e-246 pts36C G PTS system sugar-specific permease component
HFHCMLFP_02682 1.3e-51 sgcB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HFHCMLFP_02683 2.1e-82 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFHCMLFP_02684 2.3e-142 K DeoR C terminal sensor domain
HFHCMLFP_02685 2.1e-162 J Methyltransferase domain
HFHCMLFP_02686 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HFHCMLFP_02688 7.9e-117 alkD L DNA alkylation repair enzyme
HFHCMLFP_02689 2.2e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFHCMLFP_02690 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFHCMLFP_02691 8.1e-171 ykoT GT2 M Glycosyl transferase family 2
HFHCMLFP_02692 5.2e-119 lssY 3.6.1.27 I phosphatase
HFHCMLFP_02693 6.8e-116 dedA S SNARE-like domain protein
HFHCMLFP_02694 1.9e-240 T PhoQ Sensor
HFHCMLFP_02695 1.6e-126 K Transcriptional regulatory protein, C terminal
HFHCMLFP_02696 7e-272 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HFHCMLFP_02697 4.3e-275 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HFHCMLFP_02698 0.0 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
HFHCMLFP_02700 1.7e-08 S Addiction module antitoxin, RelB DinJ family
HFHCMLFP_02701 0.0
HFHCMLFP_02703 1.1e-107
HFHCMLFP_02704 1.1e-84
HFHCMLFP_02705 3.2e-63 mga K M protein trans-acting positive regulator
HFHCMLFP_02706 2.4e-128 mga K transcriptional antiterminator
HFHCMLFP_02707 1.9e-117 K Helix-turn-helix domain, rpiR family
HFHCMLFP_02708 3.6e-82 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HFHCMLFP_02709 6.1e-67 S Uncharacterised protein family UPF0047
HFHCMLFP_02710 3.6e-75 tpiA 5.3.1.1 G Triose-phosphate isomerase
HFHCMLFP_02711 1.6e-96 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HFHCMLFP_02712 5.9e-30 2.7.1.200 G Phosphotransferase system, galactitol-specific IIB component
HFHCMLFP_02713 3e-158 G PTS system sugar-specific permease component
HFHCMLFP_02714 2.5e-27 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFHCMLFP_02716 1.5e-81 manR K PRD domain
HFHCMLFP_02717 1.5e-200 S DUF218 domain
HFHCMLFP_02718 3.1e-136 4.1.2.14 S KDGP aldolase
HFHCMLFP_02719 1e-204 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
HFHCMLFP_02720 7.1e-214 dho 3.5.2.3 S Amidohydrolase family
HFHCMLFP_02721 3.1e-119 S Domain of unknown function (DUF4310)
HFHCMLFP_02722 4.9e-137 S Domain of unknown function (DUF4311)
HFHCMLFP_02723 8.1e-58 S Domain of unknown function (DUF4312)
HFHCMLFP_02724 6.9e-62 S Glycine-rich SFCGS
HFHCMLFP_02725 7.3e-56 S PRD domain
HFHCMLFP_02726 0.0 K Mga helix-turn-helix domain
HFHCMLFP_02727 5.3e-124 tal 2.2.1.2 H Pfam:Transaldolase
HFHCMLFP_02728 1.3e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HFHCMLFP_02729 5.4e-206 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HFHCMLFP_02730 6.3e-102 srlA G PTS system enzyme II sorbitol-specific factor
HFHCMLFP_02731 2.5e-89 gutM K Glucitol operon activator protein (GutM)
HFHCMLFP_02732 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
HFHCMLFP_02733 5e-145 IQ NAD dependent epimerase/dehydratase family
HFHCMLFP_02734 9.2e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HFHCMLFP_02735 9e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HFHCMLFP_02736 5e-167 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HFHCMLFP_02737 5.7e-138 repA K DeoR C terminal sensor domain
HFHCMLFP_02738 9.6e-115 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HFHCMLFP_02739 9.7e-46 sgaB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HFHCMLFP_02740 3.5e-280 ulaA S PTS system sugar-specific permease component
HFHCMLFP_02741 1.1e-80 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFHCMLFP_02742 1.9e-216 ulaG S Beta-lactamase superfamily domain
HFHCMLFP_02743 3.4e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFHCMLFP_02744 8.2e-196 C Zinc-binding dehydrogenase
HFHCMLFP_02745 2.6e-91 4.1.2.13 G DeoC/LacD family aldolase
HFHCMLFP_02746 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HFHCMLFP_02747 1.1e-158 G PTS system mannose/fructose/sorbose family IID component
HFHCMLFP_02748 1.7e-126 G PTS system sorbose-specific iic component
HFHCMLFP_02749 3.6e-82 2.7.1.191 G PTS system sorbose subfamily IIB component
HFHCMLFP_02750 1e-72 2.7.1.191 G PTS system fructose IIA component
HFHCMLFP_02751 2.2e-204 gutB 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HFHCMLFP_02752 5.4e-133 K DeoR C terminal sensor domain
HFHCMLFP_02753 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HFHCMLFP_02754 3.2e-156 bglK_1 GK ROK family
HFHCMLFP_02755 6.1e-182 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
HFHCMLFP_02756 2.6e-255 3.5.1.18 E Peptidase family M20/M25/M40
HFHCMLFP_02757 1.1e-130 ymfC K UTRA
HFHCMLFP_02758 2.7e-304 aspD 4.1.1.12 E Aminotransferase
HFHCMLFP_02759 2e-214 uhpT EGP Major facilitator Superfamily
HFHCMLFP_02760 2.4e-208 3.2.1.51 GH29 G Alpha-L-fucosidase
HFHCMLFP_02761 3.7e-67 S Domain of unknown function (DUF4428)
HFHCMLFP_02762 4.1e-270 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HFHCMLFP_02763 6.8e-203 C Zinc-binding dehydrogenase
HFHCMLFP_02764 3.7e-154 G PTS system mannose/fructose/sorbose family IID component
HFHCMLFP_02765 1.8e-136 G PTS system sorbose-specific iic component
HFHCMLFP_02766 2.1e-82 2.7.1.191 G PTS system sorbose subfamily IIB component
HFHCMLFP_02767 7.2e-71 ahaA 2.7.1.191 G PTS system fructose IIA component
HFHCMLFP_02768 2.2e-284 licR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFHCMLFP_02769 8.9e-34 G Fructose-bisphosphate aldolase class-II
HFHCMLFP_02770 1.6e-117 G Fructose-bisphosphate aldolase class-II
HFHCMLFP_02771 8.4e-279 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HFHCMLFP_02772 8.3e-257 gatC G PTS system sugar-specific permease component
HFHCMLFP_02773 1.1e-47 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HFHCMLFP_02774 8.4e-79 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFHCMLFP_02775 6.9e-161 gatY G Fructose-bisphosphate aldolase class-II
HFHCMLFP_02776 5.3e-133 farR K Helix-turn-helix domain
HFHCMLFP_02777 7.8e-88 hisA 5.3.1.16 M Acetyltransferase (GNAT) domain
HFHCMLFP_02778 2.1e-100 laaE K Transcriptional regulator PadR-like family
HFHCMLFP_02779 1.6e-288 chaT1 EGP Major facilitator Superfamily
HFHCMLFP_02780 6.7e-87 K Acetyltransferase (GNAT) domain
HFHCMLFP_02781 2.8e-93 yveA 3.5.1.19 Q Isochorismatase family
HFHCMLFP_02782 2.4e-46 6.3.4.4 S Zeta toxin
HFHCMLFP_02783 2.7e-128 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HFHCMLFP_02784 1.2e-103 IQ KR domain
HFHCMLFP_02785 1.8e-65 2.7.1.191 G PTS system sorbose subfamily IIB component
HFHCMLFP_02786 8e-36 2.7.1.191 G PTS system fructose IIA component
HFHCMLFP_02787 1.6e-246 G PTS system sorbose-specific iic component
HFHCMLFP_02788 5.3e-152 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HFHCMLFP_02789 1.3e-81 K Helix-turn-helix domain, rpiR family
HFHCMLFP_02790 6.1e-54
HFHCMLFP_02791 3.9e-07 S Protein of unknown function (DUF3923)
HFHCMLFP_02792 1.1e-95 K Helix-turn-helix domain
HFHCMLFP_02793 4.4e-121 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HFHCMLFP_02794 5.9e-73 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFHCMLFP_02795 5.6e-253 ugpB G Bacterial extracellular solute-binding protein
HFHCMLFP_02796 3.4e-149 ugpE G ABC transporter permease
HFHCMLFP_02797 2.5e-164 ugpA P ABC-type sugar transport systems, permease components
HFHCMLFP_02798 1.5e-211 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HFHCMLFP_02799 1.2e-266 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFHCMLFP_02800 9.9e-108 pncA Q Isochorismatase family
HFHCMLFP_02801 1.2e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
HFHCMLFP_02802 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
HFHCMLFP_02803 1.2e-146 3.5.2.6 V Beta-lactamase enzyme family
HFHCMLFP_02804 9.5e-192 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HFHCMLFP_02805 3.3e-194 blaA6 V Beta-lactamase
HFHCMLFP_02806 5.4e-156 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HFHCMLFP_02807 8.9e-162 ybbH_2 K Helix-turn-helix domain, rpiR family
HFHCMLFP_02808 3.1e-81 2.7.1.191 G PTS system sorbose subfamily IIB component
HFHCMLFP_02809 8.3e-151 G PTS system mannose/fructose/sorbose family IID component
HFHCMLFP_02810 3.1e-129 G PTS system sorbose-specific iic component
HFHCMLFP_02811 5.9e-202 S endonuclease exonuclease phosphatase family protein
HFHCMLFP_02812 3e-173 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HFHCMLFP_02813 2e-137 draG 3.2.2.24 O ADP-ribosylglycohydrolase
HFHCMLFP_02814 9.9e-52 sugE U Multidrug resistance protein
HFHCMLFP_02815 4.7e-134 S -acetyltransferase
HFHCMLFP_02816 2.9e-90 MA20_25245 K FR47-like protein
HFHCMLFP_02817 1.3e-93 hisB 2.7.7.71, 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19, 5.3.1.28, 6.3.2.10 GT9 E HAD-hyrolase-like
HFHCMLFP_02818 3e-190 1.1.1.1 C nadph quinone reductase
HFHCMLFP_02819 1.6e-137 wzb 3.1.3.48 T Tyrosine phosphatase family
HFHCMLFP_02820 2.6e-78 K Acetyltransferase (GNAT) domain
HFHCMLFP_02821 1.2e-42 K helix_turn_helix, mercury resistance
HFHCMLFP_02822 1.4e-123 1.1.1.219 GM Male sterility protein
HFHCMLFP_02823 5.2e-42
HFHCMLFP_02824 2.5e-77 yiaC K Acetyltransferase (GNAT) domain
HFHCMLFP_02825 3.7e-76 2.3.1.82 K Acetyltransferase (GNAT) domain
HFHCMLFP_02826 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFHCMLFP_02827 4.1e-198 ybiR P Citrate transporter
HFHCMLFP_02828 1.2e-69
HFHCMLFP_02829 1e-259 E Peptidase dimerisation domain
HFHCMLFP_02830 1.5e-297 E ABC transporter, substratebinding protein
HFHCMLFP_02831 1.2e-102
HFHCMLFP_02832 0.0 cadA P P-type ATPase
HFHCMLFP_02833 1.6e-76 hsp3 O Belongs to the small heat shock protein (HSP20) family
HFHCMLFP_02834 4.1e-71 S Iron-sulphur cluster biosynthesis
HFHCMLFP_02835 1e-211 htrA 3.4.21.107 O serine protease
HFHCMLFP_02837 1.2e-154 vicX 3.1.26.11 S domain protein
HFHCMLFP_02838 1.3e-140 yycI S YycH protein
HFHCMLFP_02839 3.3e-256 yycH S YycH protein
HFHCMLFP_02840 0.0 vicK 2.7.13.3 T Histidine kinase
HFHCMLFP_02841 8.1e-131 K response regulator
HFHCMLFP_02842 1.5e-121 3.1.1.24 S Alpha/beta hydrolase family
HFHCMLFP_02843 4.2e-259 arpJ P ABC transporter permease
HFHCMLFP_02844 3.7e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFHCMLFP_02845 2.4e-264 argH 4.3.2.1 E argininosuccinate lyase
HFHCMLFP_02846 3.1e-214 S Bacterial protein of unknown function (DUF871)
HFHCMLFP_02847 1.6e-73 S Domain of unknown function (DUF3284)
HFHCMLFP_02848 3.6e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCMLFP_02849 4e-130 K UTRA
HFHCMLFP_02850 1.3e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFHCMLFP_02851 2.4e-53 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HFHCMLFP_02852 7e-106 speG J Acetyltransferase (GNAT) domain
HFHCMLFP_02853 4.9e-84 F NUDIX domain
HFHCMLFP_02854 2.5e-89 S AAA domain
HFHCMLFP_02855 1e-113 ycaC Q Isochorismatase family
HFHCMLFP_02856 2.1e-242 ydiC1 EGP Major Facilitator Superfamily
HFHCMLFP_02857 2e-214 yeaN P Transporter, major facilitator family protein
HFHCMLFP_02858 1.4e-170 iolS C Aldo keto reductase
HFHCMLFP_02859 3.4e-64 manO S Domain of unknown function (DUF956)
HFHCMLFP_02860 2.5e-169 manN G system, mannose fructose sorbose family IID component
HFHCMLFP_02861 8.7e-121 manY G PTS system
HFHCMLFP_02862 8.1e-182 manL 2.7.1.191, 2.7.1.206 G PTS system sorbose subfamily IIB component
HFHCMLFP_02863 2.4e-218 EGP Major facilitator Superfamily
HFHCMLFP_02865 1.2e-188 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_02866 3.2e-150 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_02867 1.1e-158 K Helix-turn-helix XRE-family like proteins
HFHCMLFP_02869 3.1e-287 glnP P ABC transporter permease
HFHCMLFP_02870 3.1e-133 glnQ E ABC transporter, ATP-binding protein
HFHCMLFP_02871 3.4e-31
HFHCMLFP_02872 8.8e-237 G Bacterial extracellular solute-binding protein
HFHCMLFP_02873 1.5e-129 S Protein of unknown function (DUF975)
HFHCMLFP_02874 4.9e-41 yqkB S Iron-sulphur cluster biosynthesis
HFHCMLFP_02875 3.4e-52
HFHCMLFP_02876 2.9e-68 S Bacterial PH domain
HFHCMLFP_02877 6.3e-269 ydbT S Bacterial PH domain
HFHCMLFP_02878 1.1e-144 S AAA ATPase domain
HFHCMLFP_02879 5e-167 yniA G Phosphotransferase enzyme family
HFHCMLFP_02880 3.4e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFHCMLFP_02881 1.5e-264 glnP P ABC transporter
HFHCMLFP_02882 8e-266 glnP P ABC transporter
HFHCMLFP_02883 3.7e-99 ydaF J Acetyltransferase (GNAT) domain
HFHCMLFP_02884 3.6e-106 S Stage II sporulation protein M
HFHCMLFP_02885 2.1e-142 yeaC S ATPase family associated with various cellular activities (AAA)
HFHCMLFP_02886 2.3e-184 yeaD S Protein of unknown function DUF58
HFHCMLFP_02887 0.0 yebA E Transglutaminase/protease-like homologues
HFHCMLFP_02888 2.8e-215 lsgC M Glycosyl transferases group 1
HFHCMLFP_02889 4.8e-90 maa 2.3.1.79 S Maltose acetyltransferase
HFHCMLFP_02890 5.5e-144 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
HFHCMLFP_02891 2.7e-255 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HFHCMLFP_02892 9.7e-114 S Bacteriocin-protection, YdeI or OmpD-Associated
HFHCMLFP_02893 2.2e-35 yjdF S Protein of unknown function (DUF2992)
HFHCMLFP_02894 3.7e-213 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HFHCMLFP_02895 2.3e-38 maeN C 2-hydroxycarboxylate transporter family
HFHCMLFP_02896 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_02897 5.3e-171 maeN C 2-hydroxycarboxylate transporter family
HFHCMLFP_02898 7e-270 dpiB 2.7.13.3 T Single cache domain 3
HFHCMLFP_02899 4.8e-120 dpiA KT cheY-homologous receiver domain
HFHCMLFP_02900 5e-151 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
HFHCMLFP_02901 6.7e-95 M1-431 S Protein of unknown function (DUF1706)
HFHCMLFP_02902 3.9e-66
HFHCMLFP_02903 3e-224 yagE E Amino acid permease
HFHCMLFP_02904 2.8e-171 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HFHCMLFP_02905 1.8e-127 sip L Belongs to the 'phage' integrase family
HFHCMLFP_02906 1.4e-12 K Transcriptional regulator
HFHCMLFP_02907 7.1e-12 S sequence-specific DNA binding
HFHCMLFP_02913 3.3e-75 L Bifunctional DNA primase/polymerase, N-terminal
HFHCMLFP_02914 1.3e-68 S Virulence-associated protein E
HFHCMLFP_02915 1.3e-19
HFHCMLFP_02918 4.7e-25
HFHCMLFP_02920 2.1e-221 sip L Belongs to the 'phage' integrase family
HFHCMLFP_02921 2.3e-07 K Cro/C1-type HTH DNA-binding domain
HFHCMLFP_02922 2.9e-39
HFHCMLFP_02923 1.5e-57
HFHCMLFP_02924 2.8e-16
HFHCMLFP_02925 9.5e-26
HFHCMLFP_02926 2.5e-27
HFHCMLFP_02927 5.1e-24
HFHCMLFP_02928 3.8e-156 L Bifunctional DNA primase/polymerase, N-terminal
HFHCMLFP_02929 3.6e-271 S Virulence-associated protein E
HFHCMLFP_02932 9e-78 terS L Phage terminase, small subunit
HFHCMLFP_02933 0.0 terL S overlaps another CDS with the same product name
HFHCMLFP_02934 3.9e-21
HFHCMLFP_02935 5.4e-220 S Phage portal protein
HFHCMLFP_02936 1.5e-270 S Phage capsid family
HFHCMLFP_02937 8.7e-47 S Phage gp6-like head-tail connector protein
HFHCMLFP_02938 7.4e-13 S Phage head-tail joining protein
HFHCMLFP_02939 1.5e-15
HFHCMLFP_02940 2.2e-14 ytgB S Transglycosylase associated protein
HFHCMLFP_02942 1e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFHCMLFP_02943 6.6e-181 D Alpha beta
HFHCMLFP_02944 1.4e-186 lipA I Carboxylesterase family
HFHCMLFP_02945 5.1e-207 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HFHCMLFP_02946 1.1e-77 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFHCMLFP_02947 0.0 mtlR K Mga helix-turn-helix domain
HFHCMLFP_02948 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HFHCMLFP_02949 6.9e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFHCMLFP_02950 3.3e-149 S haloacid dehalogenase-like hydrolase
HFHCMLFP_02951 3.1e-43
HFHCMLFP_02952 5.2e-10
HFHCMLFP_02953 3.6e-183 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFHCMLFP_02954 1.1e-124 V ABC transporter
HFHCMLFP_02955 6.4e-205 bacI V MacB-like periplasmic core domain
HFHCMLFP_02956 0.0 M Leucine rich repeats (6 copies)
HFHCMLFP_02957 3.3e-200 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
HFHCMLFP_02958 3.4e-106 amd 3.5.1.47 E Peptidase family M20/M25/M40
HFHCMLFP_02959 1.9e-90 amd 3.5.1.47 E Peptidase family M20/M25/M40
HFHCMLFP_02960 2.6e-80 S Threonine/Serine exporter, ThrE
HFHCMLFP_02961 1.3e-134 thrE S Putative threonine/serine exporter
HFHCMLFP_02963 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFHCMLFP_02964 8.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFHCMLFP_02965 8.2e-129 jag S R3H domain protein
HFHCMLFP_02966 2.2e-135 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFHCMLFP_02967 2.1e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFHCMLFP_02968 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HFHCMLFP_02970 3.4e-23
HFHCMLFP_02972 1.6e-71
HFHCMLFP_02973 5.7e-70
HFHCMLFP_02974 3.8e-125 tnp L DDE domain
HFHCMLFP_02976 1.3e-101 D CobQ CobB MinD ParA nucleotide binding domain protein
HFHCMLFP_02977 2.5e-94 repE K Primase C terminal 1 (PriCT-1)
HFHCMLFP_02978 2.8e-10 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HFHCMLFP_02979 1.9e-58 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HFHCMLFP_02980 5.6e-80 tnp2PF3 L Transposase DDE domain
HFHCMLFP_02981 3.9e-44 relB L Addiction module antitoxin, RelB DinJ family
HFHCMLFP_02982 7.4e-86
HFHCMLFP_02983 1.2e-40
HFHCMLFP_02984 1e-25
HFHCMLFP_02985 0.0 L MobA MobL family protein
HFHCMLFP_02986 2.5e-43 L 4.5 Transposon and IS
HFHCMLFP_02987 6.1e-154 L 4.5 Transposon and IS
HFHCMLFP_02988 4.5e-49
HFHCMLFP_02989 5.8e-126 tnp L DDE domain
HFHCMLFP_02990 1.8e-80 3.1.21.3 V type I restriction modification DNA specificity domain protein
HFHCMLFP_02991 1.3e-15 S PASTA domain
HFHCMLFP_02992 5.3e-49 S Protein of unknown function (DUF1093)
HFHCMLFP_02993 1.1e-113 L Resolvase, N terminal domain
HFHCMLFP_02994 1e-44 ligA 6.5.1.2 L BRCA1 C Terminus (BRCT) domain
HFHCMLFP_02995 3.3e-135 yvdE K helix_turn _helix lactose operon repressor
HFHCMLFP_02996 2.5e-134 malG P ABC transporter permease
HFHCMLFP_02997 2.1e-204 malF P Binding-protein-dependent transport system inner membrane component
HFHCMLFP_02998 3.5e-166 malE G Bacterial extracellular solute-binding protein
HFHCMLFP_02999 6.6e-229 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HFHCMLFP_03000 7.2e-174 msmX P Belongs to the ABC transporter superfamily
HFHCMLFP_03001 4.8e-72 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HFHCMLFP_03002 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HFHCMLFP_03003 1.8e-248 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HFHCMLFP_03004 7.5e-228 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HFHCMLFP_03005 1e-45 L 4.5 Transposon and IS
HFHCMLFP_03006 3.7e-148 L hmm pf00665
HFHCMLFP_03007 2.6e-132 L Helix-turn-helix domain
HFHCMLFP_03008 8.9e-45 L 4.5 Transposon and IS
HFHCMLFP_03009 1.4e-172 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_03010 4.7e-160 3.4.11.5 I Alpha/beta hydrolase family
HFHCMLFP_03011 1e-156 E D-aminopeptidase
HFHCMLFP_03012 9.8e-208 pepA E M42 glutamyl aminopeptidase
HFHCMLFP_03013 3.2e-83 E ABC transporter, substratebinding protein
HFHCMLFP_03014 1e-81 repB L Initiator Replication protein
HFHCMLFP_03016 1.4e-10
HFHCMLFP_03018 3e-229 ybfG M peptidoglycan-binding domain-containing protein
HFHCMLFP_03019 1e-178 L Transposase and inactivated derivatives, IS30 family
HFHCMLFP_03020 6.8e-167 ybfG M peptidoglycan-binding domain-containing protein
HFHCMLFP_03021 1.7e-07
HFHCMLFP_03022 1.1e-13
HFHCMLFP_03023 4.6e-11 yokH G SMI1 / KNR4 family
HFHCMLFP_03024 2.7e-78 V HNH endonuclease
HFHCMLFP_03025 5.3e-48 repB L Protein involved in initiation of plasmid replication
HFHCMLFP_03026 3.6e-11
HFHCMLFP_03027 5.3e-49 S Protein of unknown function (DUF1093)
HFHCMLFP_03028 1.3e-15 S PASTA domain
HFHCMLFP_03029 5.8e-89 3.1.21.3 V type I restriction modification DNA specificity domain protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)