ORF_ID e_value Gene_name EC_number CAZy COGs Description
IOGPPLLF_00001 5.6e-157 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
IOGPPLLF_00002 1.3e-77 S CRISPR-associated protein (Cas_Csn2)
IOGPPLLF_00003 7.5e-126 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IOGPPLLF_00004 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IOGPPLLF_00005 1.4e-13
IOGPPLLF_00006 5.6e-272
IOGPPLLF_00007 7.6e-299 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
IOGPPLLF_00009 6.5e-229 3.1.21.3 V Type I restriction modification DNA specificity domain
IOGPPLLF_00010 2e-180 V Abi-like protein
IOGPPLLF_00011 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IOGPPLLF_00012 1.4e-59 S Bacterial mobilisation protein (MobC)
IOGPPLLF_00013 0.0 ltrBE1 U Relaxase/Mobilisation nuclease domain
IOGPPLLF_00014 4.7e-105
IOGPPLLF_00017 4.4e-259 L Phage integrase, N-terminal SAM-like domain
IOGPPLLF_00019 7.9e-17 M Belongs to the glycosyl hydrolase 30 family
IOGPPLLF_00020 8.1e-98 M Belongs to the glycosyl hydrolase 30 family
IOGPPLLF_00021 5.7e-191 1.1.1.65 C Aldo/keto reductase family
IOGPPLLF_00022 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
IOGPPLLF_00023 0.0 lmrA1 V ABC transporter, ATP-binding protein
IOGPPLLF_00024 0.0 lmrA2 V ABC transporter transmembrane region
IOGPPLLF_00025 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
IOGPPLLF_00026 1.3e-107 S Phosphatidylethanolamine-binding protein
IOGPPLLF_00027 0.0 pepD E Peptidase family C69
IOGPPLLF_00028 2.9e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
IOGPPLLF_00029 1.5e-61 S Macrophage migration inhibitory factor (MIF)
IOGPPLLF_00030 2.6e-97 S GtrA-like protein
IOGPPLLF_00031 6.2e-263 EGP Major facilitator Superfamily
IOGPPLLF_00032 1.1e-126 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
IOGPPLLF_00033 6.9e-143
IOGPPLLF_00034 5.8e-138 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
IOGPPLLF_00035 8.6e-201 P NMT1/THI5 like
IOGPPLLF_00036 9.9e-123 S HAD hydrolase, family IA, variant 3
IOGPPLLF_00038 6.3e-298 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOGPPLLF_00039 4.5e-94 S Domain of unknown function (DUF4143)
IOGPPLLF_00040 8.1e-64 S Domain of unknown function (DUF4143)
IOGPPLLF_00043 3.7e-251 S Calcineurin-like phosphoesterase
IOGPPLLF_00044 2.8e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
IOGPPLLF_00045 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOGPPLLF_00046 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOGPPLLF_00047 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
IOGPPLLF_00049 5.4e-182 S CAAX protease self-immunity
IOGPPLLF_00050 2.1e-221 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
IOGPPLLF_00051 3.7e-254 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOGPPLLF_00052 3.1e-224 G Transmembrane secretion effector
IOGPPLLF_00053 2.6e-129 K Bacterial regulatory proteins, tetR family
IOGPPLLF_00054 4e-125
IOGPPLLF_00055 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOGPPLLF_00056 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOGPPLLF_00057 2.3e-168 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
IOGPPLLF_00058 8.4e-188
IOGPPLLF_00059 7.9e-180
IOGPPLLF_00060 8.5e-163 trxA2 O Tetratricopeptide repeat
IOGPPLLF_00061 1.4e-118 cyaA 4.6.1.1 S CYTH
IOGPPLLF_00064 6.3e-185 K Bacterial regulatory proteins, lacI family
IOGPPLLF_00065 5.3e-18 4.2.1.68 M carboxylic acid catabolic process
IOGPPLLF_00066 6.7e-65 4.2.1.68 M Enolase C-terminal domain-like
IOGPPLLF_00067 6.8e-164 IQ KR domain
IOGPPLLF_00069 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
IOGPPLLF_00070 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
IOGPPLLF_00071 6.8e-181 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IOGPPLLF_00072 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IOGPPLLF_00073 1.1e-305 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOGPPLLF_00074 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IOGPPLLF_00075 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
IOGPPLLF_00076 5.2e-240 hom 1.1.1.3 E Homoserine dehydrogenase
IOGPPLLF_00077 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOGPPLLF_00078 5.2e-278 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
IOGPPLLF_00079 5.4e-65
IOGPPLLF_00080 6.1e-58
IOGPPLLF_00081 5.4e-164 V ATPases associated with a variety of cellular activities
IOGPPLLF_00082 3.3e-256 V Efflux ABC transporter, permease protein
IOGPPLLF_00083 1.9e-167 mdcF S Transporter, auxin efflux carrier (AEC) family protein
IOGPPLLF_00084 4.9e-240 dapE 3.5.1.18 E Peptidase dimerisation domain
IOGPPLLF_00085 0.0 rne 3.1.26.12 J Ribonuclease E/G family
IOGPPLLF_00086 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
IOGPPLLF_00087 3.1e-40 rpmA J Ribosomal L27 protein
IOGPPLLF_00088 1.8e-214 K Psort location Cytoplasmic, score
IOGPPLLF_00089 1.8e-298 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOGPPLLF_00090 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOGPPLLF_00091 2e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
IOGPPLLF_00093 1.8e-31 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOGPPLLF_00094 3.5e-117 nusG K Participates in transcription elongation, termination and antitermination
IOGPPLLF_00095 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
IOGPPLLF_00096 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
IOGPPLLF_00097 1.3e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IOGPPLLF_00098 3.7e-201 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IOGPPLLF_00099 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
IOGPPLLF_00100 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOGPPLLF_00101 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IOGPPLLF_00102 3.3e-116
IOGPPLLF_00104 2.3e-176 T Pfam Adenylate and Guanylate cyclase catalytic domain
IOGPPLLF_00105 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
IOGPPLLF_00106 1.5e-78 ssb1 L Single-stranded DNA-binding protein
IOGPPLLF_00107 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOGPPLLF_00108 6.6e-70 rplI J Binds to the 23S rRNA
IOGPPLLF_00109 5.9e-35 S Parallel beta-helix repeats
IOGPPLLF_00110 2.3e-35 E Domain of unknown function (DUF5011)
IOGPPLLF_00112 1.1e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
IOGPPLLF_00113 1.3e-129 M Protein of unknown function (DUF3152)
IOGPPLLF_00114 5.4e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOGPPLLF_00115 2.2e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IOGPPLLF_00116 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
IOGPPLLF_00117 0.0 inlJ M domain protein
IOGPPLLF_00118 7.4e-281 M LPXTG cell wall anchor motif
IOGPPLLF_00119 2.8e-213 3.4.22.70 M Sortase family
IOGPPLLF_00120 3.6e-82 S Domain of unknown function (DUF4854)
IOGPPLLF_00121 2.4e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
IOGPPLLF_00122 4.8e-27 2.1.1.72 S Protein conserved in bacteria
IOGPPLLF_00123 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOGPPLLF_00124 1.6e-132 M Mechanosensitive ion channel
IOGPPLLF_00125 3.8e-119 K Bacterial regulatory proteins, tetR family
IOGPPLLF_00126 1.5e-139 MA20_36090 S Psort location Cytoplasmic, score 8.87
IOGPPLLF_00127 1.2e-232 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
IOGPPLLF_00128 1.1e-66
IOGPPLLF_00131 7.2e-43 K Transcriptional regulator
IOGPPLLF_00132 0.0 fadD 6.2.1.3 I AMP-binding enzyme
IOGPPLLF_00133 3.5e-07 S Scramblase
IOGPPLLF_00134 1.9e-31
IOGPPLLF_00139 3e-31 K Helix-turn-helix domain
IOGPPLLF_00140 2.7e-210 S Poxvirus D5 protein-like
IOGPPLLF_00145 4.7e-94 S Bacterial mobilisation protein (MobC)
IOGPPLLF_00146 9.3e-225 S Relaxase/Mobilisation nuclease domain
IOGPPLLF_00147 3e-28 virC1 D Involved in chromosome partitioning
IOGPPLLF_00148 2.5e-59 virC1 D Involved in chromosome partitioning
IOGPPLLF_00149 1.4e-28
IOGPPLLF_00150 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IOGPPLLF_00151 5.3e-300 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
IOGPPLLF_00152 6.8e-140
IOGPPLLF_00153 6e-104 3.1.21.3 L Type I restriction modification DNA specificity domain
IOGPPLLF_00154 2.8e-304 L Recombinase
IOGPPLLF_00155 4e-128 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
IOGPPLLF_00156 4.4e-233 K Helix-turn-helix XRE-family like proteins
IOGPPLLF_00157 3.7e-54 relB L RelB antitoxin
IOGPPLLF_00158 2.6e-17 T Toxic component of a toxin-antitoxin (TA) module
IOGPPLLF_00159 5.9e-132 K helix_turn_helix, mercury resistance
IOGPPLLF_00160 6.6e-243 yxiO S Vacuole effluxer Atg22 like
IOGPPLLF_00162 6.5e-201 yegV G pfkB family carbohydrate kinase
IOGPPLLF_00163 1.4e-29 rpmB J Ribosomal L28 family
IOGPPLLF_00164 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
IOGPPLLF_00165 3.8e-219 steT E amino acid
IOGPPLLF_00168 0.0
IOGPPLLF_00169 2e-219 U Sodium:dicarboxylate symporter family
IOGPPLLF_00170 8.9e-122 rsmD 2.1.1.171 L Conserved hypothetical protein 95
IOGPPLLF_00171 3.1e-107 XK27_02070 S Nitroreductase family
IOGPPLLF_00172 7.6e-82 hsp20 O Hsp20/alpha crystallin family
IOGPPLLF_00173 1.1e-168 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IOGPPLLF_00174 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOGPPLLF_00175 1.8e-34 CP_0960 S Belongs to the UPF0109 family
IOGPPLLF_00176 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IOGPPLLF_00177 8.5e-295 ydfD EK Alanine-glyoxylate amino-transferase
IOGPPLLF_00178 1.3e-93 argO S LysE type translocator
IOGPPLLF_00179 9e-220 S Endonuclease/Exonuclease/phosphatase family
IOGPPLLF_00180 8.4e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOGPPLLF_00181 3.2e-164 P Cation efflux family
IOGPPLLF_00182 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOGPPLLF_00183 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
IOGPPLLF_00184 0.0 yjjK S ABC transporter
IOGPPLLF_00185 2e-58 S Protein of unknown function (DUF3039)
IOGPPLLF_00186 1.7e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOGPPLLF_00187 3.6e-107
IOGPPLLF_00188 1.6e-111 yceD S Uncharacterized ACR, COG1399
IOGPPLLF_00189 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IOGPPLLF_00190 3e-139 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOGPPLLF_00191 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
IOGPPLLF_00192 7.6e-92 ilvN 2.2.1.6 E ACT domain
IOGPPLLF_00194 7.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOGPPLLF_00195 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IOGPPLLF_00196 1.7e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOGPPLLF_00197 2.4e-176 S Auxin Efflux Carrier
IOGPPLLF_00200 0.0 pgi 5.3.1.9 G Belongs to the GPI family
IOGPPLLF_00201 3.3e-190
IOGPPLLF_00204 6.9e-201
IOGPPLLF_00206 3e-120 mgtC S MgtC family
IOGPPLLF_00207 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
IOGPPLLF_00208 6.9e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
IOGPPLLF_00209 2.5e-275 abcT3 P ATPases associated with a variety of cellular activities
IOGPPLLF_00210 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
IOGPPLLF_00211 5.2e-173 K Putative sugar-binding domain
IOGPPLLF_00212 7.5e-212 gatC G PTS system sugar-specific permease component
IOGPPLLF_00213 8e-293 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
IOGPPLLF_00214 1.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
IOGPPLLF_00215 1.1e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
IOGPPLLF_00216 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOGPPLLF_00217 1.8e-158 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IOGPPLLF_00218 2.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOGPPLLF_00219 8.7e-201 K helix_turn _helix lactose operon repressor
IOGPPLLF_00220 4.9e-10 tnp7109-21 L Integrase core domain
IOGPPLLF_00221 0.0 fadD 6.2.1.3 I AMP-binding enzyme
IOGPPLLF_00222 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IOGPPLLF_00223 8.1e-111 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IOGPPLLF_00226 2.2e-174 G Glycosyl hydrolases family 43
IOGPPLLF_00227 2.5e-103 G Glycosyl hydrolases family 43
IOGPPLLF_00228 5.9e-203 K helix_turn _helix lactose operon repressor
IOGPPLLF_00229 9.3e-11 3.2.1.14 GH18 EM Domain of unknown function (DUF5011)
IOGPPLLF_00230 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
IOGPPLLF_00231 6.2e-134 L Protein of unknown function (DUF1524)
IOGPPLLF_00232 5.5e-226 mntH P H( )-stimulated, divalent metal cation uptake system
IOGPPLLF_00233 1.5e-305 EGP Major facilitator Superfamily
IOGPPLLF_00234 7.7e-144 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IOGPPLLF_00235 7.1e-94 lacG G Binding-protein-dependent transport system inner membrane component
IOGPPLLF_00236 4.7e-109 M1-530 S Protein of unknown function (DUF4127)
IOGPPLLF_00237 1.3e-57 2.7.1.2 GK ROK family
IOGPPLLF_00238 4.9e-85 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IOGPPLLF_00241 2e-122 topB 5.99.1.2 L DNA topoisomerase
IOGPPLLF_00242 2e-67 topB 5.99.1.2 L DNA topoisomerase
IOGPPLLF_00244 3.6e-69
IOGPPLLF_00245 6e-58 S pathogenesis
IOGPPLLF_00246 5.8e-35 L Psort location Cytoplasmic, score 8.87
IOGPPLLF_00247 2.8e-164 tnp7109-2 L PFAM Transposase, Mutator family
IOGPPLLF_00248 2.9e-104 L Integrase core domain
IOGPPLLF_00249 1.4e-12 L Transposase
IOGPPLLF_00250 5.4e-104 K cell envelope-related transcriptional attenuator
IOGPPLLF_00252 2.2e-213
IOGPPLLF_00253 1.3e-179 S G5
IOGPPLLF_00254 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
IOGPPLLF_00255 2.8e-119 F Domain of unknown function (DUF4916)
IOGPPLLF_00256 1.5e-160 mhpC I Alpha/beta hydrolase family
IOGPPLLF_00257 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
IOGPPLLF_00258 0.0 enhA_2 S L,D-transpeptidase catalytic domain
IOGPPLLF_00259 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
IOGPPLLF_00260 4.1e-240 S Uncharacterized conserved protein (DUF2183)
IOGPPLLF_00261 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
IOGPPLLF_00262 2.4e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IOGPPLLF_00263 9.9e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
IOGPPLLF_00264 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
IOGPPLLF_00265 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
IOGPPLLF_00266 1.9e-219 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
IOGPPLLF_00267 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
IOGPPLLF_00268 3.1e-139 glpR K DeoR C terminal sensor domain
IOGPPLLF_00269 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
IOGPPLLF_00270 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
IOGPPLLF_00271 8.6e-243 EGP Sugar (and other) transporter
IOGPPLLF_00272 4.2e-43 gcvR T Belongs to the UPF0237 family
IOGPPLLF_00273 4.7e-252 S UPF0210 protein
IOGPPLLF_00274 9.9e-109
IOGPPLLF_00275 1.1e-06 S Membrane
IOGPPLLF_00276 6.9e-121 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOGPPLLF_00277 1.5e-67 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
IOGPPLLF_00278 5.5e-30 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G xyloglucan:xyloglucosyl transferase activity
IOGPPLLF_00279 3e-184 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
IOGPPLLF_00280 3.3e-110
IOGPPLLF_00281 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOGPPLLF_00282 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOGPPLLF_00283 1.3e-96 T Forkhead associated domain
IOGPPLLF_00284 9.2e-67 B Belongs to the OprB family
IOGPPLLF_00285 6.3e-165 3.1.3.16 T Sigma factor PP2C-like phosphatases
IOGPPLLF_00286 0.0 E Transglutaminase-like superfamily
IOGPPLLF_00287 1.8e-224 S Protein of unknown function DUF58
IOGPPLLF_00288 2.8e-190 S ATPase family associated with various cellular activities (AAA)
IOGPPLLF_00289 3.5e-126 S Fibronectin type 3 domain
IOGPPLLF_00290 9.2e-251 S Fibronectin type 3 domain
IOGPPLLF_00291 0.0 S Fibronectin type 3 domain
IOGPPLLF_00292 5.2e-270 KLT Protein tyrosine kinase
IOGPPLLF_00293 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
IOGPPLLF_00294 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
IOGPPLLF_00295 4.3e-158 K -acetyltransferase
IOGPPLLF_00296 1.3e-257 G Major Facilitator Superfamily
IOGPPLLF_00297 2.9e-66 gsiA P ATPase activity
IOGPPLLF_00298 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
IOGPPLLF_00299 1e-09 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
IOGPPLLF_00300 6.4e-24 relB L RelB antitoxin
IOGPPLLF_00301 1.1e-35 L Transposase
IOGPPLLF_00302 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOGPPLLF_00303 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOGPPLLF_00304 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOGPPLLF_00305 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
IOGPPLLF_00306 6.5e-286 O Subtilase family
IOGPPLLF_00307 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOGPPLLF_00308 2.6e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOGPPLLF_00309 1.4e-270 S zinc finger
IOGPPLLF_00310 1.5e-112 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
IOGPPLLF_00311 2.9e-229 aspB E Aminotransferase class-V
IOGPPLLF_00312 6.9e-157 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
IOGPPLLF_00313 1.9e-130 tmp1 S Domain of unknown function (DUF4391)
IOGPPLLF_00314 2.6e-149 moeB 2.7.7.80 H ThiF family
IOGPPLLF_00315 1.6e-255 cdr OP Sulfurtransferase TusA
IOGPPLLF_00316 1.2e-180 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
IOGPPLLF_00319 2.5e-203 S Endonuclease/Exonuclease/phosphatase family
IOGPPLLF_00320 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOGPPLLF_00321 4.2e-272 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOGPPLLF_00322 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
IOGPPLLF_00323 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOGPPLLF_00325 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
IOGPPLLF_00326 2.9e-165
IOGPPLLF_00327 9.4e-255 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
IOGPPLLF_00328 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
IOGPPLLF_00329 5.8e-89 K MarR family
IOGPPLLF_00330 0.0 V ABC transporter, ATP-binding protein
IOGPPLLF_00331 0.0 V ABC transporter transmembrane region
IOGPPLLF_00332 3.6e-169 S Patatin-like phospholipase
IOGPPLLF_00333 3.9e-153 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IOGPPLLF_00334 1.5e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
IOGPPLLF_00335 7.6e-115 S Vitamin K epoxide reductase
IOGPPLLF_00336 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
IOGPPLLF_00337 6.1e-32 S Protein of unknown function (DUF3107)
IOGPPLLF_00338 1.2e-245 mphA S Aminoglycoside phosphotransferase
IOGPPLLF_00339 3.6e-282 uvrD2 3.6.4.12 L DNA helicase
IOGPPLLF_00340 5.6e-278 S Zincin-like metallopeptidase
IOGPPLLF_00341 1.4e-150 lon T Belongs to the peptidase S16 family
IOGPPLLF_00342 5.5e-66 S Protein of unknown function (DUF3052)
IOGPPLLF_00343 2e-194 K helix_turn _helix lactose operon repressor
IOGPPLLF_00344 1.2e-61 S Thiamine-binding protein
IOGPPLLF_00345 5.4e-164 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IOGPPLLF_00346 7.6e-230 O AAA domain (Cdc48 subfamily)
IOGPPLLF_00347 9.2e-35
IOGPPLLF_00348 6.7e-311 L Recombinase zinc beta ribbon domain
IOGPPLLF_00349 2.1e-235 K Psort location Cytoplasmic, score 8.87
IOGPPLLF_00350 1.2e-112
IOGPPLLF_00351 1.1e-172 P FtsX-like permease family
IOGPPLLF_00352 1.6e-115 V ATPases associated with a variety of cellular activities
IOGPPLLF_00353 1.7e-94 K WHG domain
IOGPPLLF_00354 6.7e-120 S Psort location CytoplasmicMembrane, score
IOGPPLLF_00355 1.6e-55 S Psort location Cytoplasmic, score
IOGPPLLF_00356 7.2e-39 S Psort location Cytoplasmic, score
IOGPPLLF_00357 5.1e-34 L Excisionase from transposon Tn916
IOGPPLLF_00358 2.4e-110 K Helix-turn-helix domain
IOGPPLLF_00359 2.1e-249 L Phage integrase family
IOGPPLLF_00360 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IOGPPLLF_00361 2e-158 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IOGPPLLF_00362 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
IOGPPLLF_00363 3e-300 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
IOGPPLLF_00364 2e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOGPPLLF_00365 2.1e-230 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOGPPLLF_00366 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOGPPLLF_00367 2.1e-42 yggT S YGGT family
IOGPPLLF_00368 9.7e-90 3.1.21.3 V DivIVA protein
IOGPPLLF_00369 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOGPPLLF_00370 5.8e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IOGPPLLF_00372 6e-63
IOGPPLLF_00373 1.2e-146 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
IOGPPLLF_00374 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOGPPLLF_00375 2.9e-188 ftsE D Cell division ATP-binding protein FtsE
IOGPPLLF_00376 2.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
IOGPPLLF_00377 9.7e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
IOGPPLLF_00378 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IOGPPLLF_00379 2.5e-146 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
IOGPPLLF_00380 1.3e-61
IOGPPLLF_00382 4.8e-200 2.7.11.1 NU Tfp pilus assembly protein FimV
IOGPPLLF_00383 6.4e-221 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IOGPPLLF_00384 3.9e-235 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IOGPPLLF_00385 1.2e-291 I acetylesterase activity
IOGPPLLF_00386 3.9e-142 recO L Involved in DNA repair and RecF pathway recombination
IOGPPLLF_00387 1.8e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOGPPLLF_00388 1.5e-191 ywqG S Domain of unknown function (DUF1963)
IOGPPLLF_00389 2.9e-36 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
IOGPPLLF_00390 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
IOGPPLLF_00391 1e-97 S zinc-ribbon domain
IOGPPLLF_00392 2e-46 yhbY J CRS1_YhbY
IOGPPLLF_00393 0.0 4.2.1.53 S MCRA family
IOGPPLLF_00394 1.7e-20 4.2.1.53 S MCRA family
IOGPPLLF_00397 7.5e-202 K WYL domain
IOGPPLLF_00398 1.3e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
IOGPPLLF_00399 3.8e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
IOGPPLLF_00400 1.3e-75 yneG S Domain of unknown function (DUF4186)
IOGPPLLF_00403 2.6e-180 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
IOGPPLLF_00404 5.5e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IOGPPLLF_00405 2.5e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IOGPPLLF_00406 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
IOGPPLLF_00407 1.7e-112
IOGPPLLF_00408 4.8e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IOGPPLLF_00409 4.9e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
IOGPPLLF_00410 5.4e-283 S Uncharacterized protein conserved in bacteria (DUF2252)
IOGPPLLF_00411 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
IOGPPLLF_00412 1.4e-248 S Domain of unknown function (DUF5067)
IOGPPLLF_00413 5.3e-57 EGP Major facilitator Superfamily
IOGPPLLF_00414 1.4e-176 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
IOGPPLLF_00415 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
IOGPPLLF_00416 2.4e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
IOGPPLLF_00417 3.9e-173
IOGPPLLF_00418 3.2e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOGPPLLF_00419 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
IOGPPLLF_00420 6e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOGPPLLF_00421 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOGPPLLF_00422 4.9e-50 M Lysin motif
IOGPPLLF_00423 1.1e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOGPPLLF_00424 3.2e-228 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IOGPPLLF_00425 0.0 L DNA helicase
IOGPPLLF_00426 1.3e-90 mraZ K Belongs to the MraZ family
IOGPPLLF_00427 9.2e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOGPPLLF_00428 2.8e-63 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IOGPPLLF_00429 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
IOGPPLLF_00430 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOGPPLLF_00431 2.2e-282 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOGPPLLF_00432 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOGPPLLF_00433 3.9e-265 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOGPPLLF_00434 4e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
IOGPPLLF_00435 6.5e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOGPPLLF_00436 3.4e-294 murC 6.3.2.8 M Belongs to the MurCDEF family
IOGPPLLF_00437 5.8e-148 ftsQ 6.3.2.4 D Cell division protein FtsQ
IOGPPLLF_00438 1.3e-37
IOGPPLLF_00440 2.9e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOGPPLLF_00441 2.9e-235 G Major Facilitator Superfamily
IOGPPLLF_00442 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
IOGPPLLF_00443 1.3e-224 GK ROK family
IOGPPLLF_00444 2.9e-131 cutC P Participates in the control of copper homeostasis
IOGPPLLF_00445 7e-217 GK ROK family
IOGPPLLF_00446 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOGPPLLF_00447 9.6e-244 nagA 3.5.1.25 G Amidohydrolase family
IOGPPLLF_00448 1.7e-304 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
IOGPPLLF_00449 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
IOGPPLLF_00450 5.1e-191 dppC EP Binding-protein-dependent transport system inner membrane component
IOGPPLLF_00451 0.0 P Belongs to the ABC transporter superfamily
IOGPPLLF_00452 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
IOGPPLLF_00453 4.3e-97 3.6.1.55 F NUDIX domain
IOGPPLLF_00455 4.7e-283 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
IOGPPLLF_00456 0.0 smc D Required for chromosome condensation and partitioning
IOGPPLLF_00457 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
IOGPPLLF_00458 2.1e-243 yxbA 6.3.1.12 S ATP-grasp
IOGPPLLF_00459 1.1e-228 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
IOGPPLLF_00460 6.8e-192 V Acetyltransferase (GNAT) domain
IOGPPLLF_00461 2.6e-297 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOGPPLLF_00462 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
IOGPPLLF_00463 2e-64
IOGPPLLF_00464 1.4e-194 galM 5.1.3.3 G Aldose 1-epimerase
IOGPPLLF_00465 5.5e-178 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IOGPPLLF_00467 7.1e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOGPPLLF_00468 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOGPPLLF_00469 1.8e-133 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
IOGPPLLF_00470 7.1e-68 S Spermine/spermidine synthase domain
IOGPPLLF_00471 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOGPPLLF_00472 2.1e-25 rpmI J Ribosomal protein L35
IOGPPLLF_00473 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOGPPLLF_00474 1.9e-178 xerD D recombinase XerD
IOGPPLLF_00475 1.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
IOGPPLLF_00476 5.5e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOGPPLLF_00477 5.4e-113 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOGPPLLF_00478 2.1e-148 nrtR 3.6.1.55 F NUDIX hydrolase
IOGPPLLF_00479 9.8e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IOGPPLLF_00480 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
IOGPPLLF_00481 5.9e-163 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
IOGPPLLF_00482 2.6e-236 iscS1 2.8.1.7 E Aminotransferase class-V
IOGPPLLF_00483 0.0 typA T Elongation factor G C-terminus
IOGPPLLF_00484 3.5e-91
IOGPPLLF_00485 5.5e-197 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
IOGPPLLF_00486 1.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
IOGPPLLF_00487 7.3e-42
IOGPPLLF_00488 1.6e-185 xerC D Belongs to the 'phage' integrase family. XerC subfamily
IOGPPLLF_00489 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
IOGPPLLF_00490 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
IOGPPLLF_00491 0.0 oppD P Belongs to the ABC transporter superfamily
IOGPPLLF_00492 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
IOGPPLLF_00493 3.5e-274 pepC 3.4.22.40 E Peptidase C1-like family
IOGPPLLF_00494 1.1e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
IOGPPLLF_00495 3.2e-139 S Protein of unknown function (DUF3710)
IOGPPLLF_00496 5.4e-128 S Protein of unknown function (DUF3159)
IOGPPLLF_00497 2.2e-248 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOGPPLLF_00498 2e-109
IOGPPLLF_00499 0.0 ctpE P E1-E2 ATPase
IOGPPLLF_00500 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IOGPPLLF_00502 1.1e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
IOGPPLLF_00503 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
IOGPPLLF_00504 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOGPPLLF_00505 8.5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOGPPLLF_00506 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOGPPLLF_00508 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IOGPPLLF_00509 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOGPPLLF_00510 2.8e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
IOGPPLLF_00511 0.0 arc O AAA ATPase forming ring-shaped complexes
IOGPPLLF_00512 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
IOGPPLLF_00513 2.4e-158 hisN 3.1.3.25 G Inositol monophosphatase family
IOGPPLLF_00514 1.6e-10 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
IOGPPLLF_00515 7.7e-277 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IOGPPLLF_00516 8.1e-42 hup L Belongs to the bacterial histone-like protein family
IOGPPLLF_00517 0.0 S Lysylphosphatidylglycerol synthase TM region
IOGPPLLF_00518 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
IOGPPLLF_00519 8.3e-290 S PGAP1-like protein
IOGPPLLF_00521 2.7e-74
IOGPPLLF_00522 1.6e-148 S von Willebrand factor (vWF) type A domain
IOGPPLLF_00523 6.8e-190 S von Willebrand factor (vWF) type A domain
IOGPPLLF_00524 6.4e-94
IOGPPLLF_00525 1.5e-175 S Protein of unknown function DUF58
IOGPPLLF_00526 5e-196 moxR S ATPase family associated with various cellular activities (AAA)
IOGPPLLF_00527 1.1e-144 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOGPPLLF_00528 7.6e-71 S LytR cell envelope-related transcriptional attenuator
IOGPPLLF_00529 2.2e-44 cspA K 'Cold-shock' DNA-binding domain
IOGPPLLF_00530 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOGPPLLF_00531 1.7e-10 S Proteins of 100 residues with WXG
IOGPPLLF_00532 1.2e-163
IOGPPLLF_00533 1.6e-134 KT Response regulator receiver domain protein
IOGPPLLF_00534 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOGPPLLF_00535 1e-66 cspB K 'Cold-shock' DNA-binding domain
IOGPPLLF_00536 5.6e-200 S Protein of unknown function (DUF3027)
IOGPPLLF_00537 4.7e-185 uspA T Belongs to the universal stress protein A family
IOGPPLLF_00538 0.0 clpC O ATPase family associated with various cellular activities (AAA)
IOGPPLLF_00542 1.5e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
IOGPPLLF_00543 8.7e-262 hisS 6.1.1.21 J Histidyl-tRNA synthetase
IOGPPLLF_00544 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IOGPPLLF_00545 1.4e-63 K helix_turn_helix, Lux Regulon
IOGPPLLF_00546 5.8e-85 S Aminoacyl-tRNA editing domain
IOGPPLLF_00547 3.6e-140 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
IOGPPLLF_00548 9.5e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
IOGPPLLF_00549 6.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
IOGPPLLF_00550 8.2e-199 gluD E Binding-protein-dependent transport system inner membrane component
IOGPPLLF_00551 6e-194 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
IOGPPLLF_00552 0.0 L DEAD DEAH box helicase
IOGPPLLF_00553 2.2e-257 rarA L Recombination factor protein RarA
IOGPPLLF_00555 3.4e-256 EGP Major facilitator Superfamily
IOGPPLLF_00556 0.0 ecfA GP ABC transporter, ATP-binding protein
IOGPPLLF_00557 1.1e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOGPPLLF_00559 5.1e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
IOGPPLLF_00560 2.3e-212 E Aminotransferase class I and II
IOGPPLLF_00561 3.4e-138 bioM P ATPases associated with a variety of cellular activities
IOGPPLLF_00562 5.8e-76 2.8.2.22 S Arylsulfotransferase Ig-like domain
IOGPPLLF_00563 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOGPPLLF_00564 0.0 S Tetratricopeptide repeat
IOGPPLLF_00565 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOGPPLLF_00566 6.3e-210 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IOGPPLLF_00567 8.8e-161 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
IOGPPLLF_00568 3.1e-286 glnA 6.3.1.2 E glutamine synthetase
IOGPPLLF_00569 7.4e-141 S Domain of unknown function (DUF4191)
IOGPPLLF_00570 8.9e-281 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IOGPPLLF_00571 5.5e-104 S Protein of unknown function (DUF3043)
IOGPPLLF_00572 1.2e-258 argE E Peptidase dimerisation domain
IOGPPLLF_00573 8.3e-191 V N-Acetylmuramoyl-L-alanine amidase
IOGPPLLF_00574 1.3e-148 ytrE V ATPases associated with a variety of cellular activities
IOGPPLLF_00575 2.9e-196
IOGPPLLF_00576 3.6e-230 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
IOGPPLLF_00577 0.0 S Uncharacterised protein family (UPF0182)
IOGPPLLF_00578 9.6e-208 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOGPPLLF_00579 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOGPPLLF_00580 8.6e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
IOGPPLLF_00582 1.8e-130 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IOGPPLLF_00583 4.3e-197 GM GDP-mannose 4,6 dehydratase
IOGPPLLF_00584 3.6e-151 GM ABC-2 type transporter
IOGPPLLF_00585 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
IOGPPLLF_00586 1.7e-96 2.3.1.183 M Acetyltransferase (GNAT) domain
IOGPPLLF_00587 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOGPPLLF_00588 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOGPPLLF_00589 2.2e-298 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
IOGPPLLF_00590 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
IOGPPLLF_00591 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOGPPLLF_00592 3.2e-101 divIC D Septum formation initiator
IOGPPLLF_00593 2e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
IOGPPLLF_00594 2.6e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
IOGPPLLF_00596 6.1e-97
IOGPPLLF_00597 8.8e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
IOGPPLLF_00598 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
IOGPPLLF_00599 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOGPPLLF_00601 2.3e-107
IOGPPLLF_00602 2.6e-142 yplQ S Haemolysin-III related
IOGPPLLF_00603 4e-284 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOGPPLLF_00604 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
IOGPPLLF_00605 0.0 D FtsK/SpoIIIE family
IOGPPLLF_00606 2.7e-269 K Cell envelope-related transcriptional attenuator domain
IOGPPLLF_00607 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
IOGPPLLF_00608 0.0 S Glycosyl transferase, family 2
IOGPPLLF_00609 2.6e-259
IOGPPLLF_00610 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
IOGPPLLF_00611 5e-156 cof 5.2.1.8 T Eukaryotic phosphomannomutase
IOGPPLLF_00612 6.3e-131 ctsW S Phosphoribosyl transferase domain
IOGPPLLF_00613 2.1e-72 rulA 3.4.21.88 KT Peptidase S24-like
IOGPPLLF_00614 4.3e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOGPPLLF_00615 1.9e-127 T Response regulator receiver domain protein
IOGPPLLF_00616 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOGPPLLF_00617 5.1e-102 carD K CarD-like/TRCF domain
IOGPPLLF_00618 1.9e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IOGPPLLF_00619 4.3e-139 znuB U ABC 3 transport family
IOGPPLLF_00620 1.8e-164 znuC P ATPases associated with a variety of cellular activities
IOGPPLLF_00621 3.7e-172 P Zinc-uptake complex component A periplasmic
IOGPPLLF_00622 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOGPPLLF_00623 3.3e-243 rpsA J Ribosomal protein S1
IOGPPLLF_00624 2.7e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOGPPLLF_00625 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOGPPLLF_00626 5.6e-178 terC P Integral membrane protein, TerC family
IOGPPLLF_00627 1.9e-272 pyk 2.7.1.40 G Pyruvate kinase
IOGPPLLF_00628 7.4e-109 aspA 3.6.1.13 L NUDIX domain
IOGPPLLF_00630 9.2e-120 pdtaR T Response regulator receiver domain protein
IOGPPLLF_00631 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOGPPLLF_00632 2.7e-171 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
IOGPPLLF_00633 3.7e-120 3.6.1.13 L NUDIX domain
IOGPPLLF_00634 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
IOGPPLLF_00635 6.4e-217 ykiI
IOGPPLLF_00637 2.1e-134 L Phage integrase family
IOGPPLLF_00638 2.9e-108 3.4.13.21 E Peptidase family S51
IOGPPLLF_00639 2.9e-276 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IOGPPLLF_00640 1.3e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOGPPLLF_00641 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IOGPPLLF_00642 6.8e-71 XK27_07020 S Domain of unknown function (DUF1846)
IOGPPLLF_00643 2.2e-80
IOGPPLLF_00644 4.2e-09 S Domain of unknown function (DUF4339)
IOGPPLLF_00645 3e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IOGPPLLF_00646 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
IOGPPLLF_00647 6.8e-190 pit P Phosphate transporter family
IOGPPLLF_00648 1.1e-115 MA20_27875 P Protein of unknown function DUF47
IOGPPLLF_00649 1.3e-120 K helix_turn_helix, Lux Regulon
IOGPPLLF_00650 5.4e-234 T Histidine kinase
IOGPPLLF_00651 3.4e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
IOGPPLLF_00652 3.8e-187 V ATPases associated with a variety of cellular activities
IOGPPLLF_00653 8.1e-227 V ABC-2 family transporter protein
IOGPPLLF_00654 6e-250 V ABC-2 family transporter protein
IOGPPLLF_00655 1.3e-284 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
IOGPPLLF_00656 4.4e-109
IOGPPLLF_00657 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
IOGPPLLF_00658 1.8e-220 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
IOGPPLLF_00659 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IOGPPLLF_00660 3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOGPPLLF_00661 1.4e-10 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOGPPLLF_00662 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IOGPPLLF_00663 1.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
IOGPPLLF_00664 7.7e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOGPPLLF_00665 2.3e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
IOGPPLLF_00666 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOGPPLLF_00667 2.7e-160 K Helix-turn-helix domain, rpiR family
IOGPPLLF_00668 5.8e-230 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
IOGPPLLF_00669 3.3e-43 S Memo-like protein
IOGPPLLF_00671 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOGPPLLF_00672 8.5e-179 adh3 C Zinc-binding dehydrogenase
IOGPPLLF_00673 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOGPPLLF_00674 2.4e-228 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOGPPLLF_00675 5.1e-74 zur P Belongs to the Fur family
IOGPPLLF_00676 1.3e-44
IOGPPLLF_00677 1e-153 S TIGRFAM TIGR03943 family protein
IOGPPLLF_00678 1.4e-201 ycgR S Predicted permease
IOGPPLLF_00679 2.3e-23 J Ribosomal L32p protein family
IOGPPLLF_00680 8.2e-15 rpmJ J Ribosomal protein L36
IOGPPLLF_00681 2e-42 rpmE2 J Ribosomal protein L31
IOGPPLLF_00682 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOGPPLLF_00683 6.1e-48 rpmB J Ribosomal L28 family
IOGPPLLF_00684 1.8e-139 S cobalamin synthesis protein
IOGPPLLF_00685 1.3e-162 P Zinc-uptake complex component A periplasmic
IOGPPLLF_00687 0.0 lysX S Uncharacterised conserved protein (DUF2156)
IOGPPLLF_00688 2.7e-247 S Putative esterase
IOGPPLLF_00689 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
IOGPPLLF_00690 5e-240 purD 6.3.4.13 F Belongs to the GARS family
IOGPPLLF_00691 2e-186 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IOGPPLLF_00692 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOGPPLLF_00693 9.8e-302 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
IOGPPLLF_00694 2e-32
IOGPPLLF_00695 1.8e-68 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOGPPLLF_00696 7.8e-16 K DNA-binding transcription factor activity
IOGPPLLF_00697 2.3e-104 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
IOGPPLLF_00698 1.7e-95 S Protein of unknown function (DUF4230)
IOGPPLLF_00699 1.3e-103
IOGPPLLF_00700 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
IOGPPLLF_00701 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IOGPPLLF_00702 8.3e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IOGPPLLF_00703 0.0 M Parallel beta-helix repeats
IOGPPLLF_00705 5.4e-228 M Glycosyl transferase 4-like domain
IOGPPLLF_00706 6.5e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
IOGPPLLF_00708 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOGPPLLF_00709 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOGPPLLF_00710 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOGPPLLF_00711 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOGPPLLF_00712 0.0 S Esterase-like activity of phytase
IOGPPLLF_00713 1.3e-71 EGP Transmembrane secretion effector
IOGPPLLF_00714 7.8e-130 EGP Transmembrane secretion effector
IOGPPLLF_00716 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOGPPLLF_00717 1.3e-93 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOGPPLLF_00718 1e-237 carA 6.3.5.5 F Belongs to the CarA family
IOGPPLLF_00719 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
IOGPPLLF_00720 2.6e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
IOGPPLLF_00721 0.0 S Protein of unknown function DUF262
IOGPPLLF_00722 1.1e-116 K helix_turn_helix, Lux Regulon
IOGPPLLF_00723 3.2e-267 T Histidine kinase
IOGPPLLF_00724 1e-97 S Domain of unknown function (DUF5067)
IOGPPLLF_00725 6.6e-132 ybhL S Belongs to the BI1 family
IOGPPLLF_00726 4.1e-170 ydeD EG EamA-like transporter family
IOGPPLLF_00727 7.1e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
IOGPPLLF_00728 2.8e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IOGPPLLF_00729 3.1e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOGPPLLF_00730 1.2e-137 fic D Fic/DOC family
IOGPPLLF_00731 0.0 ftsK D FtsK SpoIIIE family protein
IOGPPLLF_00732 7.1e-121 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOGPPLLF_00733 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
IOGPPLLF_00734 7.3e-81 K Helix-turn-helix XRE-family like proteins
IOGPPLLF_00735 1.8e-39 S Protein of unknown function (DUF3046)
IOGPPLLF_00736 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOGPPLLF_00737 7.1e-74 recX S Modulates RecA activity
IOGPPLLF_00738 6.1e-27 marR5 K Winged helix DNA-binding domain
IOGPPLLF_00740 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOGPPLLF_00741 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOGPPLLF_00742 1.8e-190 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IOGPPLLF_00743 1.6e-108
IOGPPLLF_00744 4.6e-134 plsC2 2.3.1.51 I Phosphate acyltransferases
IOGPPLLF_00745 0.0 pknL 2.7.11.1 KLT PASTA
IOGPPLLF_00746 1e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
IOGPPLLF_00747 6.5e-122
IOGPPLLF_00748 6.3e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOGPPLLF_00749 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
IOGPPLLF_00750 2.6e-277 aspA 4.3.1.1 E Fumarase C C-terminus
IOGPPLLF_00751 5.9e-42 S Protein of unknown function (DUF2975)
IOGPPLLF_00752 0.0 lhr L DEAD DEAH box helicase
IOGPPLLF_00753 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
IOGPPLLF_00754 6.5e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
IOGPPLLF_00755 5.4e-187 S Protein of unknown function (DUF3071)
IOGPPLLF_00756 1.4e-47 S Domain of unknown function (DUF4193)
IOGPPLLF_00757 3.8e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IOGPPLLF_00758 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOGPPLLF_00759 9e-28
IOGPPLLF_00760 3.6e-233 L Phage integrase family
IOGPPLLF_00761 7.8e-131 fic D Fic/DOC family
IOGPPLLF_00762 1.1e-26
IOGPPLLF_00763 1.6e-26 L DNA integration
IOGPPLLF_00765 4.6e-73 S EcsC protein family
IOGPPLLF_00766 2e-232 hsdM 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
IOGPPLLF_00767 1.1e-205 S HipA-like C-terminal domain
IOGPPLLF_00768 3.1e-34
IOGPPLLF_00769 2.5e-208 E Belongs to the peptidase S1B family
IOGPPLLF_00770 5.7e-67 T Toxic component of a toxin-antitoxin (TA) module
IOGPPLLF_00771 1.1e-49 relB L RelB antitoxin
IOGPPLLF_00772 5.4e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOGPPLLF_00773 5.5e-166 S Sucrose-6F-phosphate phosphohydrolase
IOGPPLLF_00774 1.6e-41 P ABC-type metal ion transport system permease component
IOGPPLLF_00775 6.3e-10 P ABC-type metal ion transport system permease component
IOGPPLLF_00776 2.7e-224 S Peptidase dimerisation domain
IOGPPLLF_00777 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IOGPPLLF_00778 4.9e-40
IOGPPLLF_00779 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
IOGPPLLF_00780 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOGPPLLF_00781 4.4e-114 S Protein of unknown function (DUF3000)
IOGPPLLF_00782 6e-249 rnd 3.1.13.5 J 3'-5' exonuclease
IOGPPLLF_00783 2.8e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOGPPLLF_00784 6.1e-255 clcA_2 P Voltage gated chloride channel
IOGPPLLF_00785 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOGPPLLF_00786 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOGPPLLF_00787 8.5e-243 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOGPPLLF_00790 1.1e-233 patB 4.4.1.8 E Aminotransferase, class I II
IOGPPLLF_00791 4.5e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IOGPPLLF_00792 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
IOGPPLLF_00793 4.4e-118 safC S O-methyltransferase
IOGPPLLF_00794 6.6e-184 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
IOGPPLLF_00795 3e-71 yraN L Belongs to the UPF0102 family
IOGPPLLF_00796 1.9e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
IOGPPLLF_00797 8.8e-284 dprA 5.99.1.2 LU DNA recombination-mediator protein A
IOGPPLLF_00798 1.3e-57 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
IOGPPLLF_00799 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
IOGPPLLF_00800 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IOGPPLLF_00801 4.6e-157 S Putative ABC-transporter type IV
IOGPPLLF_00802 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
IOGPPLLF_00803 2.3e-38
IOGPPLLF_00804 2.2e-35
IOGPPLLF_00805 1.7e-140
IOGPPLLF_00806 7.3e-35 M Domain of unknown function (DUF1906)
IOGPPLLF_00807 4e-162 V ABC transporter, ATP-binding protein
IOGPPLLF_00808 0.0 MV MacB-like periplasmic core domain
IOGPPLLF_00809 0.0 phoN I PAP2 superfamily
IOGPPLLF_00810 1.5e-130 K helix_turn_helix, Lux Regulon
IOGPPLLF_00811 0.0 tcsS2 T Histidine kinase
IOGPPLLF_00812 2.2e-265 pip 3.4.11.5 S alpha/beta hydrolase fold
IOGPPLLF_00813 3.2e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOGPPLLF_00814 1.6e-166 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
IOGPPLLF_00815 3.5e-146 P NLPA lipoprotein
IOGPPLLF_00816 3.8e-187 acoA 1.2.4.1 C Dehydrogenase E1 component
IOGPPLLF_00817 2.3e-182 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
IOGPPLLF_00818 1.3e-166 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOGPPLLF_00819 1.1e-92 metI P Binding-protein-dependent transport system inner membrane component
IOGPPLLF_00820 5.4e-228 mtnE 2.6.1.83 E Aminotransferase class I and II
IOGPPLLF_00821 3e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOGPPLLF_00822 1.3e-195 int L Phage integrase, N-terminal SAM-like domain
IOGPPLLF_00823 1.7e-27 S Protein of unknown function (DUF3800)
IOGPPLLF_00824 9.7e-30
IOGPPLLF_00825 6.8e-08 int L Phage integrase, N-terminal SAM-like domain
IOGPPLLF_00826 2.6e-119 dprA LU DNA recombination-mediator protein A
IOGPPLLF_00827 8.2e-61 S competence protein
IOGPPLLF_00828 3.4e-09
IOGPPLLF_00831 5e-16
IOGPPLLF_00832 3.4e-111 L Integrase core domain
IOGPPLLF_00833 2.1e-37 L Psort location Cytoplasmic, score 8.87
IOGPPLLF_00834 8.6e-120 E Psort location Cytoplasmic, score 8.87
IOGPPLLF_00835 5.6e-59 yccF S Inner membrane component domain
IOGPPLLF_00836 2.3e-156 ksgA 2.1.1.182 J Methyltransferase domain
IOGPPLLF_00837 7.9e-66 S Cupin 2, conserved barrel domain protein
IOGPPLLF_00838 4.1e-258 KLT Protein tyrosine kinase
IOGPPLLF_00839 4.5e-79 K Psort location Cytoplasmic, score
IOGPPLLF_00840 4.1e-149
IOGPPLLF_00841 2.7e-22
IOGPPLLF_00842 9.3e-199 S Short C-terminal domain
IOGPPLLF_00843 3.9e-86 S Helix-turn-helix
IOGPPLLF_00844 5.2e-65 S Zincin-like metallopeptidase
IOGPPLLF_00845 2.1e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
IOGPPLLF_00846 1.1e-24
IOGPPLLF_00847 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IOGPPLLF_00848 2.5e-126 ypfH S Phospholipase/Carboxylesterase
IOGPPLLF_00849 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
IOGPPLLF_00851 1.4e-289 2.4.1.166 GT2 M Glycosyltransferase like family 2
IOGPPLLF_00852 8.4e-119 3.1.3.27 E haloacid dehalogenase-like hydrolase
IOGPPLLF_00853 6.6e-145 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
IOGPPLLF_00854 3.6e-186 MA20_14895 S Conserved hypothetical protein 698
IOGPPLLF_00855 5.7e-55 estB S Phospholipase/Carboxylesterase
IOGPPLLF_00856 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
IOGPPLLF_00857 2.4e-237 rutG F Permease family
IOGPPLLF_00858 1e-104 K AraC-like ligand binding domain
IOGPPLLF_00860 4.3e-46 IQ oxidoreductase activity
IOGPPLLF_00861 4.2e-136 ybbM V Uncharacterised protein family (UPF0014)
IOGPPLLF_00862 3.4e-135 ybbL V ATPases associated with a variety of cellular activities
IOGPPLLF_00863 1.7e-159 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOGPPLLF_00864 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOGPPLLF_00865 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
IOGPPLLF_00866 2.5e-86
IOGPPLLF_00867 8.5e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IOGPPLLF_00868 5.1e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IOGPPLLF_00869 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IOGPPLLF_00870 2.5e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
IOGPPLLF_00871 1.6e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOGPPLLF_00872 1.1e-84 argR K Regulates arginine biosynthesis genes
IOGPPLLF_00873 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IOGPPLLF_00874 9.5e-67 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
IOGPPLLF_00875 1.6e-178 L Phage integrase family
IOGPPLLF_00876 2.4e-30
IOGPPLLF_00877 1.9e-155 S Domain of unknown function (DUF4357)
IOGPPLLF_00878 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
IOGPPLLF_00879 2.3e-141 3.1.21.3 V type I restriction modification DNA specificity domain
IOGPPLLF_00880 3.1e-276 3.6.4.12 K Putative DNA-binding domain
IOGPPLLF_00881 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IOGPPLLF_00882 1.4e-281 argH 4.3.2.1 E argininosuccinate lyase
IOGPPLLF_00883 4e-107 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOGPPLLF_00884 1.6e-143 S Putative ABC-transporter type IV
IOGPPLLF_00885 1.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOGPPLLF_00886 1.5e-158 L Tetratricopeptide repeat
IOGPPLLF_00887 2.3e-190 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
IOGPPLLF_00889 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IOGPPLLF_00890 3.6e-104
IOGPPLLF_00891 6.8e-116 trkA P TrkA-N domain
IOGPPLLF_00892 3.5e-237 trkB P Cation transport protein
IOGPPLLF_00893 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOGPPLLF_00894 1.1e-290 recN L May be involved in recombinational repair of damaged DNA
IOGPPLLF_00895 4.1e-121 S Haloacid dehalogenase-like hydrolase
IOGPPLLF_00896 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
IOGPPLLF_00897 2.7e-177 V ATPases associated with a variety of cellular activities
IOGPPLLF_00898 2.8e-126 S ABC-2 family transporter protein
IOGPPLLF_00899 4e-122 S ABC-2 family transporter protein
IOGPPLLF_00900 1.9e-283 thrC 4.2.3.1 E Threonine synthase N terminus
IOGPPLLF_00901 4e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IOGPPLLF_00902 7.5e-92
IOGPPLLF_00903 1.6e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOGPPLLF_00904 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOGPPLLF_00906 4.6e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOGPPLLF_00907 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOGPPLLF_00908 4.2e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IOGPPLLF_00909 1.3e-78 S Bacterial PH domain
IOGPPLLF_00910 3.2e-255 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
IOGPPLLF_00912 1.2e-108
IOGPPLLF_00913 2.5e-132 C Putative TM nitroreductase
IOGPPLLF_00914 5.7e-142 yijF S Domain of unknown function (DUF1287)
IOGPPLLF_00915 2.3e-69 pdxH S Pfam:Pyridox_oxidase
IOGPPLLF_00916 4.2e-147 KT RESPONSE REGULATOR receiver
IOGPPLLF_00917 2.4e-192 V VanZ like family
IOGPPLLF_00918 2.3e-110 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
IOGPPLLF_00919 1.8e-110 ypjC S Putative ABC-transporter type IV
IOGPPLLF_00920 1.2e-150 3.6.4.12
IOGPPLLF_00922 3.4e-118 EGP Major facilitator Superfamily
IOGPPLLF_00923 9.8e-164 rpoC M heme binding
IOGPPLLF_00924 4.7e-79 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOGPPLLF_00925 2.9e-116
IOGPPLLF_00926 9.4e-132 S SOS response associated peptidase (SRAP)
IOGPPLLF_00927 4.9e-78 qseC 2.7.13.3 T Histidine kinase
IOGPPLLF_00928 6.6e-184 S Acetyltransferase (GNAT) domain
IOGPPLLF_00929 1.3e-37 J Aminoacyl-tRNA editing domain
IOGPPLLF_00930 4.9e-35 2.7.7.1, 3.6.1.13, 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
IOGPPLLF_00931 4.3e-56 K Transcriptional regulator
IOGPPLLF_00932 1.2e-97 MA20_25245 K FR47-like protein
IOGPPLLF_00933 1.2e-120 ydaF_1 J Acetyltransferase (GNAT) domain
IOGPPLLF_00934 1.5e-64 yeaO K Protein of unknown function, DUF488
IOGPPLLF_00935 2.5e-163 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IOGPPLLF_00936 2.6e-283 S Psort location Cytoplasmic, score 8.87
IOGPPLLF_00937 1.7e-113 S Domain of unknown function (DUF4194)
IOGPPLLF_00938 0.0 S Psort location Cytoplasmic, score 8.87
IOGPPLLF_00939 2e-299 E Serine carboxypeptidase
IOGPPLLF_00940 1e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IOGPPLLF_00941 3.7e-171 corA P CorA-like Mg2+ transporter protein
IOGPPLLF_00942 1.7e-168 ET Bacterial periplasmic substrate-binding proteins
IOGPPLLF_00943 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOGPPLLF_00944 4.4e-91 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
IOGPPLLF_00945 0.0 comE S Competence protein
IOGPPLLF_00946 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
IOGPPLLF_00947 1.7e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
IOGPPLLF_00948 3.3e-158 yeaZ 2.3.1.234 O Glycoprotease family
IOGPPLLF_00949 3.1e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
IOGPPLLF_00950 6.9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOGPPLLF_00952 1.2e-130 M Peptidase family M23
IOGPPLLF_00953 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
IOGPPLLF_00954 5.6e-273 G ABC transporter substrate-binding protein
IOGPPLLF_00955 2.2e-240 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
IOGPPLLF_00956 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
IOGPPLLF_00957 3.4e-91
IOGPPLLF_00958 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
IOGPPLLF_00959 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOGPPLLF_00960 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
IOGPPLLF_00961 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOGPPLLF_00962 5.2e-127 3.2.1.8 S alpha beta
IOGPPLLF_00963 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IOGPPLLF_00964 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOGPPLLF_00965 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
IOGPPLLF_00966 9.8e-230 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IOGPPLLF_00967 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IOGPPLLF_00968 1.2e-73 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IOGPPLLF_00969 1.3e-309 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IOGPPLLF_00970 9.7e-247 G Bacterial extracellular solute-binding protein
IOGPPLLF_00971 1.1e-173 G Binding-protein-dependent transport system inner membrane component
IOGPPLLF_00972 1.7e-168 G ABC transporter permease
IOGPPLLF_00973 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
IOGPPLLF_00974 6.9e-178 2.7.1.2 GK ROK family
IOGPPLLF_00975 6.4e-218 GK ROK family
IOGPPLLF_00976 2.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
IOGPPLLF_00977 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IOGPPLLF_00978 3.2e-197 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IOGPPLLF_00979 2e-302 ybiT S ABC transporter
IOGPPLLF_00980 1.7e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IOGPPLLF_00981 9.7e-240 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IOGPPLLF_00982 3.3e-118 K Transcriptional regulatory protein, C terminal
IOGPPLLF_00983 5.6e-60 V MacB-like periplasmic core domain
IOGPPLLF_00984 1.2e-77
IOGPPLLF_00985 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOGPPLLF_00986 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOGPPLLF_00987 4.4e-180 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
IOGPPLLF_00988 6.9e-178 rapZ S Displays ATPase and GTPase activities
IOGPPLLF_00989 3.1e-173 whiA K May be required for sporulation
IOGPPLLF_00990 2e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
IOGPPLLF_00991 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOGPPLLF_00992 8e-33 secG U Preprotein translocase SecG subunit
IOGPPLLF_00993 3.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IOGPPLLF_00994 8e-162 S Sucrose-6F-phosphate phosphohydrolase
IOGPPLLF_00995 1.5e-242 mepA_6 V MatE
IOGPPLLF_00998 6.8e-254 brnQ U Component of the transport system for branched-chain amino acids
IOGPPLLF_00999 1.2e-143 yoaK S Protein of unknown function (DUF1275)
IOGPPLLF_01000 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IOGPPLLF_01001 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
IOGPPLLF_01002 2.3e-221 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOGPPLLF_01003 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOGPPLLF_01004 1.7e-158 G Fructosamine kinase
IOGPPLLF_01005 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IOGPPLLF_01006 2.8e-156 S PAC2 family
IOGPPLLF_01010 4.3e-214
IOGPPLLF_01014 2.2e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOGPPLLF_01015 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOGPPLLF_01016 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
IOGPPLLF_01017 1e-131 yebC K transcriptional regulatory protein
IOGPPLLF_01018 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IOGPPLLF_01020 3.3e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOGPPLLF_01021 3e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOGPPLLF_01022 2.6e-44 yajC U Preprotein translocase subunit
IOGPPLLF_01023 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOGPPLLF_01024 1.9e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IOGPPLLF_01025 1.4e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IOGPPLLF_01026 3.2e-245
IOGPPLLF_01027 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IOGPPLLF_01028 5.7e-30
IOGPPLLF_01029 1.8e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IOGPPLLF_01030 1.7e-145 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IOGPPLLF_01031 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
IOGPPLLF_01032 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IOGPPLLF_01033 1.4e-161 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IOGPPLLF_01034 4.4e-183 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOGPPLLF_01035 8.2e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
IOGPPLLF_01036 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
IOGPPLLF_01037 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
IOGPPLLF_01038 1e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOGPPLLF_01039 1.8e-173 S Bacterial protein of unknown function (DUF881)
IOGPPLLF_01040 2.6e-31 sbp S Protein of unknown function (DUF1290)
IOGPPLLF_01041 1.2e-141 S Bacterial protein of unknown function (DUF881)
IOGPPLLF_01042 9.6e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
IOGPPLLF_01043 6.8e-119 K helix_turn_helix, mercury resistance
IOGPPLLF_01044 4.3e-62
IOGPPLLF_01046 5.7e-24 L DNA integration
IOGPPLLF_01047 7.2e-126 S GyrI-like small molecule binding domain
IOGPPLLF_01048 6.2e-90 K Putative zinc ribbon domain
IOGPPLLF_01051 7.3e-143 pgp 3.1.3.18 S HAD-hyrolase-like
IOGPPLLF_01052 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
IOGPPLLF_01053 0.0 helY L DEAD DEAH box helicase
IOGPPLLF_01054 1e-51
IOGPPLLF_01055 0.0 pafB K WYL domain
IOGPPLLF_01056 5.1e-289 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
IOGPPLLF_01058 1.3e-90 dkgB S Oxidoreductase, aldo keto reductase family protein
IOGPPLLF_01059 4e-144 4.1.1.44 S Carboxymuconolactone decarboxylase family
IOGPPLLF_01060 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOGPPLLF_01061 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IOGPPLLF_01062 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
IOGPPLLF_01063 4.7e-85 T Domain of unknown function (DUF4234)
IOGPPLLF_01064 4.2e-101 K Bacterial regulatory proteins, tetR family
IOGPPLLF_01065 3.5e-18
IOGPPLLF_01066 1.7e-47 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
IOGPPLLF_01067 3.7e-41 K Helix-turn-helix
IOGPPLLF_01068 2e-224 hipA 2.7.11.1 S HipA N-terminal domain
IOGPPLLF_01069 1.2e-66 4.1.1.44 S Cupin domain
IOGPPLLF_01070 4.4e-175 S Membrane transport protein
IOGPPLLF_01071 2.1e-91 laaE K Transcriptional regulator PadR-like family
IOGPPLLF_01072 2.3e-133 magIII L endonuclease III
IOGPPLLF_01073 9.6e-132 S Enoyl-(Acyl carrier protein) reductase
IOGPPLLF_01074 1.1e-242 vbsD V MatE
IOGPPLLF_01075 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IOGPPLLF_01076 4.5e-15 KLT Protein tyrosine kinase
IOGPPLLF_01077 2.5e-17 K Psort location Cytoplasmic, score
IOGPPLLF_01079 4.9e-130
IOGPPLLF_01080 4.7e-196 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
IOGPPLLF_01081 3e-16 K MerR family regulatory protein
IOGPPLLF_01082 2.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOGPPLLF_01083 8.2e-179 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOGPPLLF_01084 1.7e-156 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
IOGPPLLF_01085 8.9e-181 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
IOGPPLLF_01086 2.5e-280 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOGPPLLF_01087 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
IOGPPLLF_01088 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IOGPPLLF_01089 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
IOGPPLLF_01091 2.4e-158 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
IOGPPLLF_01092 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOGPPLLF_01093 2.6e-100 sixA T Phosphoglycerate mutase family
IOGPPLLF_01094 1.1e-206 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IOGPPLLF_01095 1e-178 I alpha/beta hydrolase fold
IOGPPLLF_01096 5.8e-25 rarD S Rard protein
IOGPPLLF_01097 2.4e-92 rarD 3.4.17.13 E Rard protein
IOGPPLLF_01098 1.9e-29
IOGPPLLF_01099 2.2e-122 L Transposase
IOGPPLLF_01100 1.7e-61 S Short C-terminal domain
IOGPPLLF_01101 8.2e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOGPPLLF_01102 2.1e-48 S Sel1-like repeats.
IOGPPLLF_01103 1.7e-151 ybeM S Carbon-nitrogen hydrolase
IOGPPLLF_01104 8.9e-164 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
IOGPPLLF_01105 2.5e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
IOGPPLLF_01106 3.6e-82
IOGPPLLF_01107 1e-303 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IOGPPLLF_01108 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
IOGPPLLF_01109 0.0 tetP J Elongation factor G, domain IV
IOGPPLLF_01110 2.2e-290 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
IOGPPLLF_01111 2.5e-245 hemN H Involved in the biosynthesis of porphyrin-containing compound
IOGPPLLF_01112 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOGPPLLF_01113 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
IOGPPLLF_01114 1.2e-135 S UPF0126 domain
IOGPPLLF_01115 2.7e-99 3.1.4.37 T RNA ligase
IOGPPLLF_01116 4e-46 S phosphoesterase or phosphohydrolase
IOGPPLLF_01117 2.4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
IOGPPLLF_01118 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IOGPPLLF_01119 4.8e-190 S alpha beta
IOGPPLLF_01120 3.3e-232 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IOGPPLLF_01121 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
IOGPPLLF_01122 3.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
IOGPPLLF_01123 0.0 fadD 6.2.1.3 I AMP-binding enzyme
IOGPPLLF_01124 1.5e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOGPPLLF_01125 2.4e-251 corC S CBS domain
IOGPPLLF_01126 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOGPPLLF_01127 3.4e-197 phoH T PhoH-like protein
IOGPPLLF_01128 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
IOGPPLLF_01129 7.2e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IOGPPLLF_01131 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
IOGPPLLF_01132 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOGPPLLF_01133 1.2e-108 yitW S Iron-sulfur cluster assembly protein
IOGPPLLF_01134 8.8e-101 iscU C SUF system FeS assembly protein, NifU family
IOGPPLLF_01135 8.5e-240 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOGPPLLF_01136 1.4e-144 sufC O FeS assembly ATPase SufC
IOGPPLLF_01137 3e-234 sufD O FeS assembly protein SufD
IOGPPLLF_01138 3.6e-290 sufB O FeS assembly protein SufB
IOGPPLLF_01139 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOGPPLLF_01140 2.4e-07 3.4.22.70 M Sortase family
IOGPPLLF_01141 1.7e-120 K helix_turn_helix, Lux Regulon
IOGPPLLF_01142 3.4e-15
IOGPPLLF_01143 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
IOGPPLLF_01144 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IOGPPLLF_01145 3.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IOGPPLLF_01146 6.3e-47 3.4.23.43 S Type IV leader peptidase family
IOGPPLLF_01147 7.8e-187 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IOGPPLLF_01148 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOGPPLLF_01149 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOGPPLLF_01150 1.1e-36
IOGPPLLF_01151 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
IOGPPLLF_01152 6.5e-136 pgm3 G Phosphoglycerate mutase family
IOGPPLLF_01153 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
IOGPPLLF_01154 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOGPPLLF_01155 1.9e-128 lolD V ABC transporter
IOGPPLLF_01156 3.2e-212 V FtsX-like permease family
IOGPPLLF_01157 8.2e-64 S Domain of unknown function (DUF4418)
IOGPPLLF_01158 0.0 pcrA 3.6.4.12 L DNA helicase
IOGPPLLF_01159 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
IOGPPLLF_01160 3.3e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOGPPLLF_01161 1.8e-240 pbuX F Permease family
IOGPPLLF_01163 1.4e-46 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOGPPLLF_01165 1.1e-110 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
IOGPPLLF_01166 5.8e-39
IOGPPLLF_01167 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
IOGPPLLF_01168 1.6e-179 tnp7109-21 L Integrase core domain
IOGPPLLF_01169 4.3e-47 L Transposase
IOGPPLLF_01170 1.2e-64 D MobA/MobL family
IOGPPLLF_01172 0.0 tetP J elongation factor G
IOGPPLLF_01173 4.8e-19 S Maff2 family
IOGPPLLF_01174 0.0 U Type IV secretory system Conjugative DNA transfer
IOGPPLLF_01175 2.3e-65 S Protein of unknown function (DUF3801)
IOGPPLLF_01176 5.6e-35 S Domain of unknown function (DUF5348)
IOGPPLLF_01177 3.8e-162 L Psort location Cytoplasmic, score
IOGPPLLF_01178 4.1e-169 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
IOGPPLLF_01179 5.1e-140 3.5.2.6 V Beta-lactamase enzyme family
IOGPPLLF_01180 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
IOGPPLLF_01181 1.2e-163 EG EamA-like transporter family
IOGPPLLF_01183 1.8e-120 V FtsX-like permease family
IOGPPLLF_01184 1.5e-147 S Sulfite exporter TauE/SafE
IOGPPLLF_01186 1.9e-26 L Transposase
IOGPPLLF_01187 8.4e-215 MA20_36090 S Psort location Cytoplasmic, score 8.87
IOGPPLLF_01188 1.7e-251 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
IOGPPLLF_01189 2.1e-35 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
IOGPPLLF_01190 3.1e-73 EGP Major facilitator superfamily
IOGPPLLF_01191 3.7e-179 glkA 2.7.1.2 G ROK family
IOGPPLLF_01192 1.2e-299 S ATPases associated with a variety of cellular activities
IOGPPLLF_01193 2.5e-56 EGP Major facilitator Superfamily
IOGPPLLF_01194 4.9e-159 I alpha/beta hydrolase fold
IOGPPLLF_01195 1.1e-110 S Pyridoxamine 5'-phosphate oxidase
IOGPPLLF_01197 1.3e-55 S DUF218 domain
IOGPPLLF_01198 6.2e-39 S Protein of unknown function (DUF979)
IOGPPLLF_01199 4.4e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOGPPLLF_01201 5.7e-126
IOGPPLLF_01202 4.7e-48 M domain, Protein
IOGPPLLF_01203 4e-19 M domain, Protein
IOGPPLLF_01204 5.3e-306 yjjK S ATP-binding cassette protein, ChvD family
IOGPPLLF_01205 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
IOGPPLLF_01206 7.1e-172 tesB I Thioesterase-like superfamily
IOGPPLLF_01207 1.3e-77 S Protein of unknown function (DUF3180)
IOGPPLLF_01208 2.1e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IOGPPLLF_01209 3.4e-163 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IOGPPLLF_01210 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
IOGPPLLF_01211 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOGPPLLF_01212 2.1e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IOGPPLLF_01213 1.1e-211 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOGPPLLF_01214 3.5e-261 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
IOGPPLLF_01215 1.9e-308
IOGPPLLF_01216 3.7e-168 natA V ATPases associated with a variety of cellular activities
IOGPPLLF_01217 1.3e-232 epsG M Glycosyl transferase family 21
IOGPPLLF_01218 4.6e-275 S AI-2E family transporter
IOGPPLLF_01219 4.3e-177 3.4.14.13 M Glycosyltransferase like family 2
IOGPPLLF_01220 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
IOGPPLLF_01223 4.8e-67 S Domain of unknown function (DUF4190)
IOGPPLLF_01224 6.9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IOGPPLLF_01225 1.4e-175 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOGPPLLF_01227 1e-16 S Transcription factor WhiB
IOGPPLLF_01228 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
IOGPPLLF_01229 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
IOGPPLLF_01230 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
IOGPPLLF_01231 7.5e-183 lacR K Transcriptional regulator, LacI family
IOGPPLLF_01232 5.2e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IOGPPLLF_01233 3.9e-119 K Transcriptional regulatory protein, C terminal
IOGPPLLF_01234 4.8e-101
IOGPPLLF_01235 1.9e-179 V N-Acetylmuramoyl-L-alanine amidase
IOGPPLLF_01236 2e-106 ytrE V ABC transporter
IOGPPLLF_01237 8.6e-172
IOGPPLLF_01238 1.7e-11 S Psort location CytoplasmicMembrane, score 9.99
IOGPPLLF_01239 4.7e-220 vex3 V ABC transporter permease
IOGPPLLF_01240 3.6e-211 vex1 V Efflux ABC transporter, permease protein
IOGPPLLF_01241 9.9e-112 vex2 V ABC transporter, ATP-binding protein
IOGPPLLF_01242 9.8e-49 azlD E Branched-chain amino acid transport protein (AzlD)
IOGPPLLF_01243 2.2e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
IOGPPLLF_01244 4e-95 ptpA 3.1.3.48 T low molecular weight
IOGPPLLF_01245 1.7e-127 folA 1.5.1.3 H dihydrofolate reductase
IOGPPLLF_01246 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOGPPLLF_01247 3.8e-72 attW O OsmC-like protein
IOGPPLLF_01248 1.6e-191 T Universal stress protein family
IOGPPLLF_01249 2.4e-107 M NlpC/P60 family
IOGPPLLF_01250 1.6e-175 usp 3.5.1.28 CBM50 S CHAP domain
IOGPPLLF_01251 8.5e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IOGPPLLF_01252 2.6e-39
IOGPPLLF_01253 2.3e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
IOGPPLLF_01254 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
IOGPPLLF_01255 1e-09 EGP Major facilitator Superfamily
IOGPPLLF_01256 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOGPPLLF_01257 4.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
IOGPPLLF_01258 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IOGPPLLF_01260 4.3e-217 araJ EGP Major facilitator Superfamily
IOGPPLLF_01261 0.0 S Domain of unknown function (DUF4037)
IOGPPLLF_01262 1.5e-112 S Protein of unknown function (DUF4125)
IOGPPLLF_01263 7.3e-135
IOGPPLLF_01264 3.6e-289 pspC KT PspC domain
IOGPPLLF_01265 8.9e-273 tcsS3 KT PspC domain
IOGPPLLF_01266 9.2e-126 degU K helix_turn_helix, Lux Regulon
IOGPPLLF_01267 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOGPPLLF_01269 2.3e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
IOGPPLLF_01270 4.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
IOGPPLLF_01271 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOGPPLLF_01272 1.8e-95
IOGPPLLF_01274 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
IOGPPLLF_01276 3e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOGPPLLF_01277 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
IOGPPLLF_01278 3.2e-214 I Diacylglycerol kinase catalytic domain
IOGPPLLF_01279 1.3e-151 arbG K CAT RNA binding domain
IOGPPLLF_01280 0.0 crr G pts system, glucose-specific IIABC component
IOGPPLLF_01281 4.4e-42 M Spy0128-like isopeptide containing domain
IOGPPLLF_01282 2.7e-43 M Spy0128-like isopeptide containing domain
IOGPPLLF_01284 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
IOGPPLLF_01285 4e-262 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IOGPPLLF_01286 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
IOGPPLLF_01287 3.8e-204 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOGPPLLF_01288 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IOGPPLLF_01290 1.2e-106
IOGPPLLF_01291 6.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOGPPLLF_01292 6.9e-234 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
IOGPPLLF_01293 1.6e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOGPPLLF_01294 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOGPPLLF_01295 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOGPPLLF_01296 2.8e-188 nusA K Participates in both transcription termination and antitermination
IOGPPLLF_01297 7.6e-164
IOGPPLLF_01298 6.5e-27 L Transposase and inactivated derivatives
IOGPPLLF_01299 1.7e-33
IOGPPLLF_01301 5e-153 E Transglutaminase/protease-like homologues
IOGPPLLF_01302 0.0 gcs2 S A circularly permuted ATPgrasp
IOGPPLLF_01303 6.4e-173 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOGPPLLF_01304 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
IOGPPLLF_01305 2.8e-64 rplQ J Ribosomal protein L17
IOGPPLLF_01306 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOGPPLLF_01307 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOGPPLLF_01308 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOGPPLLF_01309 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IOGPPLLF_01310 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOGPPLLF_01311 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOGPPLLF_01312 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOGPPLLF_01313 2.7e-63 rplO J binds to the 23S rRNA
IOGPPLLF_01314 1e-24 rpmD J Ribosomal protein L30p/L7e
IOGPPLLF_01315 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOGPPLLF_01316 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOGPPLLF_01317 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOGPPLLF_01318 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOGPPLLF_01319 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOGPPLLF_01320 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOGPPLLF_01321 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOGPPLLF_01322 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOGPPLLF_01323 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOGPPLLF_01324 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
IOGPPLLF_01325 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOGPPLLF_01326 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOGPPLLF_01327 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOGPPLLF_01328 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOGPPLLF_01329 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOGPPLLF_01330 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOGPPLLF_01331 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
IOGPPLLF_01332 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOGPPLLF_01333 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
IOGPPLLF_01334 3e-14 ywiC S YwiC-like protein
IOGPPLLF_01335 1e-74 ywiC S YwiC-like protein
IOGPPLLF_01336 3.8e-38 ywiC S YwiC-like protein
IOGPPLLF_01337 8.7e-167 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
IOGPPLLF_01338 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IOGPPLLF_01339 1e-234 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
IOGPPLLF_01340 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
IOGPPLLF_01341 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
IOGPPLLF_01342 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOGPPLLF_01343 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
IOGPPLLF_01344 8.9e-112
IOGPPLLF_01345 4e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
IOGPPLLF_01346 1.1e-256 M Bacterial capsule synthesis protein PGA_cap
IOGPPLLF_01348 3.1e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOGPPLLF_01349 1.2e-224 dapC E Aminotransferase class I and II
IOGPPLLF_01350 9e-61 fdxA C 4Fe-4S binding domain
IOGPPLLF_01351 6.9e-215 murB 1.3.1.98 M Cell wall formation
IOGPPLLF_01352 1.9e-25 rpmG J Ribosomal protein L33
IOGPPLLF_01356 1.3e-50 moxR S ATPase family associated with various cellular activities (AAA)
IOGPPLLF_01357 2.1e-132 bla1 3.5.2.6 V Beta-lactamase enzyme family
IOGPPLLF_01358 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOGPPLLF_01359 1e-145
IOGPPLLF_01360 2.3e-149 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
IOGPPLLF_01361 2e-120 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
IOGPPLLF_01362 3.2e-38 fmdB S Putative regulatory protein
IOGPPLLF_01363 1.4e-108 flgA NO SAF
IOGPPLLF_01364 9.6e-42
IOGPPLLF_01365 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
IOGPPLLF_01366 1e-248 T Forkhead associated domain
IOGPPLLF_01368 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOGPPLLF_01369 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOGPPLLF_01370 5.6e-186 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
IOGPPLLF_01371 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
IOGPPLLF_01373 8.8e-222 pbuO S Permease family
IOGPPLLF_01374 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
IOGPPLLF_01375 2.3e-167 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
IOGPPLLF_01376 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOGPPLLF_01377 6.2e-180 pstA P Phosphate transport system permease
IOGPPLLF_01378 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
IOGPPLLF_01379 3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
IOGPPLLF_01380 1.3e-128 KT Transcriptional regulatory protein, C terminal
IOGPPLLF_01381 1.4e-243 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
IOGPPLLF_01382 1.9e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOGPPLLF_01383 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IOGPPLLF_01384 9.1e-107 K helix_turn_helix, Arsenical Resistance Operon Repressor
IOGPPLLF_01385 2e-242 EGP Major facilitator Superfamily
IOGPPLLF_01386 4.3e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IOGPPLLF_01387 2.3e-166 L Excalibur calcium-binding domain
IOGPPLLF_01388 7.9e-268 pepC 3.4.22.40 E Peptidase C1-like family
IOGPPLLF_01389 3.4e-46 D nuclear chromosome segregation
IOGPPLLF_01390 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOGPPLLF_01391 8e-143 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IOGPPLLF_01392 7.9e-188 yfiH Q Multi-copper polyphenol oxidoreductase laccase
IOGPPLLF_01393 0.0 yegQ O Peptidase family U32 C-terminal domain
IOGPPLLF_01394 2.9e-171 L Transposase and inactivated derivatives IS30 family
IOGPPLLF_01395 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
IOGPPLLF_01396 2.2e-41 nrdH O Glutaredoxin
IOGPPLLF_01397 9.5e-98 nrdI F Probably involved in ribonucleotide reductase function
IOGPPLLF_01398 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOGPPLLF_01399 7e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOGPPLLF_01400 4.6e-74 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
IOGPPLLF_01401 0.0 S Predicted membrane protein (DUF2207)
IOGPPLLF_01402 3.7e-94 lemA S LemA family
IOGPPLLF_01403 2.3e-41 K purine nucleotide biosynthetic process
IOGPPLLF_01404 2.6e-151 xylR K purine nucleotide biosynthetic process
IOGPPLLF_01405 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IOGPPLLF_01406 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOGPPLLF_01407 4e-119
IOGPPLLF_01408 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
IOGPPLLF_01410 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
IOGPPLLF_01411 3.2e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOGPPLLF_01412 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
IOGPPLLF_01413 7.2e-308 pccB I Carboxyl transferase domain
IOGPPLLF_01414 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
IOGPPLLF_01415 4.2e-93 bioY S BioY family
IOGPPLLF_01416 1.3e-151 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
IOGPPLLF_01417 0.0
IOGPPLLF_01418 5.9e-146 QT PucR C-terminal helix-turn-helix domain
IOGPPLLF_01419 9.5e-132 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IOGPPLLF_01420 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IOGPPLLF_01421 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOGPPLLF_01422 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOGPPLLF_01423 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOGPPLLF_01424 1.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOGPPLLF_01425 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOGPPLLF_01426 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOGPPLLF_01428 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
IOGPPLLF_01429 4.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IOGPPLLF_01431 1e-44
IOGPPLLF_01432 0.0 K RNA polymerase II activating transcription factor binding
IOGPPLLF_01433 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
IOGPPLLF_01434 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IOGPPLLF_01436 1.3e-102 mntP P Probably functions as a manganese efflux pump
IOGPPLLF_01437 7e-125
IOGPPLLF_01438 1.5e-132 KT Transcriptional regulatory protein, C terminal
IOGPPLLF_01439 5.1e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOGPPLLF_01440 2.1e-293 E Bacterial extracellular solute-binding proteins, family 5 Middle
IOGPPLLF_01441 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOGPPLLF_01442 0.0 S domain protein
IOGPPLLF_01443 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
IOGPPLLF_01444 2.4e-90 lrp_3 K helix_turn_helix ASNC type
IOGPPLLF_01445 4.7e-235 E Aminotransferase class I and II
IOGPPLLF_01446 3e-306 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IOGPPLLF_01447 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
IOGPPLLF_01448 3.3e-52 S Protein of unknown function (DUF2469)
IOGPPLLF_01449 8.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
IOGPPLLF_01450 9.3e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOGPPLLF_01451 1.6e-288 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOGPPLLF_01452 1.8e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOGPPLLF_01453 1e-60 V ABC transporter
IOGPPLLF_01454 9.6e-59 V ABC transporter
IOGPPLLF_01455 2.2e-154 spoU 2.1.1.185 J RNA methyltransferase TrmH family
IOGPPLLF_01456 2.7e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOGPPLLF_01457 1.3e-214 rmuC S RmuC family
IOGPPLLF_01458 1.4e-42 csoR S Metal-sensitive transcriptional repressor
IOGPPLLF_01459 0.0 pacS 3.6.3.54 P E1-E2 ATPase
IOGPPLLF_01460 0.0 ubiB S ABC1 family
IOGPPLLF_01461 3.5e-19 S granule-associated protein
IOGPPLLF_01462 7.5e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
IOGPPLLF_01463 1.7e-282 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
IOGPPLLF_01464 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IOGPPLLF_01465 8.2e-252 dinF V MatE
IOGPPLLF_01466 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
IOGPPLLF_01467 1e-54 glnB K Nitrogen regulatory protein P-II
IOGPPLLF_01468 1.3e-219 amt U Ammonium Transporter Family
IOGPPLLF_01469 6.2e-203 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOGPPLLF_01470 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
IOGPPLLF_01471 1.5e-197 XK27_01805 M Glycosyltransferase like family 2
IOGPPLLF_01472 0.0 S Glycosyl hydrolases related to GH101 family, GH129
IOGPPLLF_01473 3.5e-304 pepD E Peptidase family C69
IOGPPLLF_01475 3.5e-85 XK26_04485 P Cobalt transport protein
IOGPPLLF_01476 9e-36
IOGPPLLF_01477 0.0 V ABC transporter transmembrane region
IOGPPLLF_01478 1.8e-301 V ABC transporter, ATP-binding protein
IOGPPLLF_01479 7.7e-82 K Winged helix DNA-binding domain
IOGPPLLF_01480 2.2e-09
IOGPPLLF_01481 3.1e-120 L Integrase core domain
IOGPPLLF_01482 4.9e-42 L Psort location Cytoplasmic, score 8.87
IOGPPLLF_01484 7e-09 S Sucrose-6F-phosphate phosphohydrolase
IOGPPLLF_01485 2.1e-162 S Sucrose-6F-phosphate phosphohydrolase
IOGPPLLF_01486 3.5e-241 S Putative ABC-transporter type IV
IOGPPLLF_01487 7e-81
IOGPPLLF_01488 1.4e-34 Q phosphatase activity
IOGPPLLF_01489 1.2e-295 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
IOGPPLLF_01490 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IOGPPLLF_01491 4.3e-49 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IOGPPLLF_01492 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOGPPLLF_01493 3.2e-68 S haloacid dehalogenase-like hydrolase
IOGPPLLF_01494 3.6e-131 yydK K UTRA
IOGPPLLF_01495 1.6e-68 S FMN_bind
IOGPPLLF_01496 5.7e-149 macB V ABC transporter, ATP-binding protein
IOGPPLLF_01497 3.4e-204 Z012_06715 V FtsX-like permease family
IOGPPLLF_01498 1.3e-222 macB_2 V ABC transporter permease
IOGPPLLF_01499 1.2e-233 S Predicted membrane protein (DUF2318)
IOGPPLLF_01500 6.4e-109 tpd P Fe2+ transport protein
IOGPPLLF_01501 1.9e-306 efeU_1 P Iron permease FTR1 family
IOGPPLLF_01502 5.9e-22 G MFS/sugar transport protein
IOGPPLLF_01503 1.2e-199 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOGPPLLF_01504 3.8e-54 S Fic/DOC family
IOGPPLLF_01505 8.3e-60 S Fic/DOC family
IOGPPLLF_01506 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOGPPLLF_01507 5e-38 ptsH G PTS HPr component phosphorylation site
IOGPPLLF_01508 1.7e-199 K helix_turn _helix lactose operon repressor
IOGPPLLF_01509 6.3e-213 holB 2.7.7.7 L DNA polymerase III
IOGPPLLF_01510 3.7e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOGPPLLF_01511 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOGPPLLF_01512 7.2e-190 3.6.1.27 I PAP2 superfamily
IOGPPLLF_01513 0.0 vpr M PA domain
IOGPPLLF_01514 4.7e-123 yplQ S Haemolysin-III related
IOGPPLLF_01515 2.4e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
IOGPPLLF_01516 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
IOGPPLLF_01517 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IOGPPLLF_01518 8.7e-278 S Calcineurin-like phosphoesterase
IOGPPLLF_01519 1.1e-14 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
IOGPPLLF_01520 1e-284 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
IOGPPLLF_01521 1.7e-116
IOGPPLLF_01522 2.6e-213 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOGPPLLF_01524 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
IOGPPLLF_01525 1.8e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
IOGPPLLF_01526 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOGPPLLF_01527 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
IOGPPLLF_01528 3.7e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
IOGPPLLF_01529 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
IOGPPLLF_01530 4.8e-55 U TadE-like protein
IOGPPLLF_01531 1.9e-41 S Protein of unknown function (DUF4244)
IOGPPLLF_01532 3.2e-15 gspF NU Type II secretion system (T2SS), protein F
IOGPPLLF_01533 8.3e-15 gspF NU Type II secretion system (T2SS), protein F
IOGPPLLF_01534 5.1e-122 U Type ii secretion system
IOGPPLLF_01535 3.4e-191 cpaF U Type II IV secretion system protein
IOGPPLLF_01536 2.6e-152 cpaE D bacterial-type flagellum organization
IOGPPLLF_01538 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IOGPPLLF_01539 1.6e-221 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
IOGPPLLF_01540 5.9e-92
IOGPPLLF_01541 1.4e-47 cbiM P PDGLE domain
IOGPPLLF_01542 2.7e-58 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IOGPPLLF_01543 1.8e-209 S Glycosyltransferase, group 2 family protein
IOGPPLLF_01544 4e-262
IOGPPLLF_01546 8.7e-27 thiS 2.8.1.10 H ThiS family
IOGPPLLF_01547 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IOGPPLLF_01548 0.0 S Psort location Cytoplasmic, score 8.87
IOGPPLLF_01549 5.3e-28 gtrB GT2 M Glycosyl transferase family 2
IOGPPLLF_01550 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
IOGPPLLF_01551 8.7e-249 V ABC transporter permease
IOGPPLLF_01552 1.9e-181 V ABC transporter
IOGPPLLF_01553 5.4e-138 T HD domain
IOGPPLLF_01554 3e-164 S Glutamine amidotransferase domain
IOGPPLLF_01556 0.0 kup P Transport of potassium into the cell
IOGPPLLF_01557 2.9e-184 tatD L TatD related DNase
IOGPPLLF_01558 2.4e-127 xylR 5.3.1.12 G MFS/sugar transport protein
IOGPPLLF_01559 5.6e-65 xylR 5.3.1.12 G MFS/sugar transport protein
IOGPPLLF_01560 1.1e-16 G Bacterial extracellular solute-binding protein
IOGPPLLF_01561 5e-74 K Transcriptional regulator
IOGPPLLF_01562 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOGPPLLF_01563 3.6e-130
IOGPPLLF_01564 8.6e-59
IOGPPLLF_01565 5.2e-168 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOGPPLLF_01566 2.7e-126 dedA S SNARE associated Golgi protein
IOGPPLLF_01568 1.6e-134 S HAD hydrolase, family IA, variant 3
IOGPPLLF_01569 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
IOGPPLLF_01570 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
IOGPPLLF_01571 5.2e-87 hspR K transcriptional regulator, MerR family
IOGPPLLF_01572 9.3e-173 dnaJ1 O DnaJ molecular chaperone homology domain
IOGPPLLF_01574 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOGPPLLF_01575 0.0 dnaK O Heat shock 70 kDa protein
IOGPPLLF_01576 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
IOGPPLLF_01577 1.1e-189 K Psort location Cytoplasmic, score
IOGPPLLF_01578 1.8e-138 G Phosphoglycerate mutase family
IOGPPLLF_01579 5.6e-69 S Protein of unknown function (DUF4235)
IOGPPLLF_01580 3e-141 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
IOGPPLLF_01581 1.1e-45
IOGPPLLF_01582 5.4e-192 M Glycosyltransferase like family 2
IOGPPLLF_01583 0.0 rgpF M Rhamnan synthesis protein F
IOGPPLLF_01584 5.5e-294 S Tetratricopeptide repeat
IOGPPLLF_01585 1.3e-208 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
IOGPPLLF_01586 3.8e-140 rgpC U Transport permease protein
IOGPPLLF_01587 1.2e-168 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IOGPPLLF_01588 2.5e-155 L Transposase, Mutator family
IOGPPLLF_01589 8.2e-106 L PFAM Integrase catalytic
IOGPPLLF_01590 2.2e-105 L transposase activity
IOGPPLLF_01591 5.9e-24 L Transposase
IOGPPLLF_01592 4.4e-45 L Transposase DDE domain
IOGPPLLF_01593 1.6e-290 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IOGPPLLF_01594 0.0 3.6.4.12 K Putative DNA-binding domain
IOGPPLLF_01595 2.5e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOGPPLLF_01596 0.0
IOGPPLLF_01597 2.3e-173 rfbJ M Glycosyl transferase family 2
IOGPPLLF_01598 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
IOGPPLLF_01599 2.1e-22 I transferase activity, transferring acyl groups other than amino-acyl groups
IOGPPLLF_01600 2.6e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOGPPLLF_01601 7.9e-63 T protein histidine kinase activity
IOGPPLLF_01602 7.7e-89 K LytTr DNA-binding domain
IOGPPLLF_01603 1e-47 S Protein of unknown function (DUF3073)
IOGPPLLF_01604 6.5e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOGPPLLF_01605 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
IOGPPLLF_01606 2.9e-180 S Amidohydrolase family
IOGPPLLF_01607 0.0 yjjP S Threonine/Serine exporter, ThrE
IOGPPLLF_01608 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IOGPPLLF_01609 7.3e-239 yhjX EGP Major facilitator Superfamily
IOGPPLLF_01610 5e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
IOGPPLLF_01611 0.0 trxB1 1.8.1.9 C Thioredoxin domain
IOGPPLLF_01612 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
IOGPPLLF_01613 6.9e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
IOGPPLLF_01614 2.7e-94 K helix_turn _helix lactose operon repressor
IOGPPLLF_01615 1.2e-241 ytfL P Transporter associated domain
IOGPPLLF_01616 1.3e-188 yddG EG EamA-like transporter family
IOGPPLLF_01617 1.9e-83 dps P Belongs to the Dps family
IOGPPLLF_01618 2.3e-136 S Protein of unknown function DUF45
IOGPPLLF_01619 4.7e-228 ulaA 2.7.1.194 S PTS system sugar-specific permease component
IOGPPLLF_01620 1.2e-10 ulaA 2.7.1.194 S PTS system sugar-specific permease component
IOGPPLLF_01621 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
IOGPPLLF_01622 8.6e-78 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IOGPPLLF_01623 2.8e-188 K helix_turn _helix lactose operon repressor
IOGPPLLF_01624 0.0 G Glycosyl hydrolase family 20, domain 2
IOGPPLLF_01627 0.0 3.2.1.55 GH51 G arabinose metabolic process
IOGPPLLF_01628 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOGPPLLF_01629 3.6e-123 gntR K FCD
IOGPPLLF_01630 1.5e-258 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IOGPPLLF_01633 1.4e-14 K Helix-turn-helix domain
IOGPPLLF_01634 3.4e-18 S Domain of unknown function (DUF4160)
IOGPPLLF_01635 9.6e-42 S Protein of unknown function (DUF2442)
IOGPPLLF_01636 6.7e-09 K helix_turn _helix lactose operon repressor
IOGPPLLF_01637 3.4e-227 I Serine aminopeptidase, S33
IOGPPLLF_01638 5.5e-188 K Periplasmic binding protein domain
IOGPPLLF_01639 7.9e-187 G Glycosyl hydrolases family 43
IOGPPLLF_01641 5.7e-21 abfA1 3.2.1.55 GH51 G arabinose metabolic process
IOGPPLLF_01642 4.6e-73 S Transmembrane domain of unknown function (DUF3566)
IOGPPLLF_01643 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOGPPLLF_01644 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOGPPLLF_01645 2e-87 S Protein of unknown function (DUF721)
IOGPPLLF_01646 2e-239 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOGPPLLF_01647 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOGPPLLF_01648 1.6e-291 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOGPPLLF_01649 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IOGPPLLF_01650 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
IOGPPLLF_01651 5e-93 jag S Putative single-stranded nucleic acids-binding domain
IOGPPLLF_01652 3.5e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IOGPPLLF_01653 3.8e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
IOGPPLLF_01654 1.8e-243 parB K Belongs to the ParB family
IOGPPLLF_01655 2.2e-202 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOGPPLLF_01656 0.0 murJ KLT MviN-like protein
IOGPPLLF_01657 0.0 M Conserved repeat domain
IOGPPLLF_01658 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
IOGPPLLF_01659 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
IOGPPLLF_01660 8.8e-113 S LytR cell envelope-related transcriptional attenuator
IOGPPLLF_01661 7.1e-168 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IOGPPLLF_01662 8.2e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOGPPLLF_01663 8.9e-220 S G5
IOGPPLLF_01665 2.4e-150 O Thioredoxin
IOGPPLLF_01666 0.0 KLT Protein tyrosine kinase
IOGPPLLF_01667 1.2e-174 K Psort location Cytoplasmic, score
IOGPPLLF_01668 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
IOGPPLLF_01669 2.5e-103 L Helix-turn-helix domain
IOGPPLLF_01670 0.0 S LPXTG-motif cell wall anchor domain protein
IOGPPLLF_01671 6.5e-245 M LPXTG-motif cell wall anchor domain protein
IOGPPLLF_01672 1.7e-166 3.4.22.70 M Sortase family
IOGPPLLF_01673 1.7e-154
IOGPPLLF_01674 1e-270 KLT Domain of unknown function (DUF4032)
IOGPPLLF_01675 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOGPPLLF_01677 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
IOGPPLLF_01678 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
IOGPPLLF_01679 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
IOGPPLLF_01680 0.0 yjcE P Sodium/hydrogen exchanger family
IOGPPLLF_01681 1.2e-145 ypfH S Phospholipase/Carboxylesterase
IOGPPLLF_01682 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOGPPLLF_01683 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
IOGPPLLF_01684 3e-144 cobB2 K Sir2 family
IOGPPLLF_01685 7.5e-258 S Domain of unknown function (DUF4143)
IOGPPLLF_01686 2e-17 yccF S Inner membrane component domain
IOGPPLLF_01687 3.5e-12
IOGPPLLF_01688 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
IOGPPLLF_01689 3.9e-43 tnp7109-21 L Integrase core domain
IOGPPLLF_01690 1.2e-66 L IstB-like ATP binding protein
IOGPPLLF_01691 4.1e-84 V ATPases associated with a variety of cellular activities
IOGPPLLF_01692 2e-73 I Sterol carrier protein
IOGPPLLF_01693 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IOGPPLLF_01695 3.4e-35
IOGPPLLF_01696 6.4e-145 gluP 3.4.21.105 S Rhomboid family
IOGPPLLF_01697 3.5e-117 L HTH-like domain
IOGPPLLF_01698 6.1e-257 L ribosomal rna small subunit methyltransferase
IOGPPLLF_01699 6.9e-67 crgA D Involved in cell division
IOGPPLLF_01700 3.5e-143 S Bacterial protein of unknown function (DUF881)
IOGPPLLF_01701 5.7e-233 srtA 3.4.22.70 M Sortase family
IOGPPLLF_01702 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
IOGPPLLF_01703 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
IOGPPLLF_01704 2e-183 T Protein tyrosine kinase
IOGPPLLF_01705 2.8e-263 pbpA M penicillin-binding protein
IOGPPLLF_01706 8e-266 rodA D Belongs to the SEDS family
IOGPPLLF_01707 6.9e-258 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
IOGPPLLF_01708 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
IOGPPLLF_01709 3e-130 fhaA T Protein of unknown function (DUF2662)
IOGPPLLF_01710 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
IOGPPLLF_01711 0.0 pip S YhgE Pip domain protein
IOGPPLLF_01712 0.0 pip S YhgE Pip domain protein
IOGPPLLF_01713 3.9e-206 pldB 3.1.1.5 I Serine aminopeptidase, S33
IOGPPLLF_01714 7.4e-167 yicL EG EamA-like transporter family
IOGPPLLF_01715 7.6e-103
IOGPPLLF_01717 6e-196 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOGPPLLF_01719 0.0 KL Domain of unknown function (DUF3427)
IOGPPLLF_01720 3e-90 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
IOGPPLLF_01721 1.6e-35 D DivIVA domain protein
IOGPPLLF_01722 2.7e-52 ybjQ S Putative heavy-metal-binding
IOGPPLLF_01723 7.6e-157 I Serine aminopeptidase, S33
IOGPPLLF_01724 2.9e-84 yjcF Q Acetyltransferase (GNAT) domain
IOGPPLLF_01726 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IOGPPLLF_01727 5.5e-243 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
IOGPPLLF_01728 0.0 cadA P E1-E2 ATPase
IOGPPLLF_01729 4.2e-272 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
IOGPPLLF_01730 5.3e-170 htpX O Belongs to the peptidase M48B family
IOGPPLLF_01732 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
IOGPPLLF_01733 1.4e-42 S Bacterial mobilisation protein (MobC)
IOGPPLLF_01734 4.4e-75 S Domain of unknown function (DUF4417)
IOGPPLLF_01736 1.9e-61
IOGPPLLF_01737 2e-64
IOGPPLLF_01738 3.9e-50 E IrrE N-terminal-like domain
IOGPPLLF_01739 2e-12 E IrrE N-terminal-like domain
IOGPPLLF_01740 3.2e-56 K Cro/C1-type HTH DNA-binding domain
IOGPPLLF_01741 4.3e-251 3.5.1.104 G Polysaccharide deacetylase
IOGPPLLF_01742 3.3e-200 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
IOGPPLLF_01743 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOGPPLLF_01744 3.7e-163 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOGPPLLF_01745 1.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOGPPLLF_01746 5.6e-197 K helix_turn _helix lactose operon repressor
IOGPPLLF_01747 4.2e-74 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
IOGPPLLF_01748 3.2e-295 scrT G Transporter major facilitator family protein
IOGPPLLF_01749 5e-254 yhjE EGP Sugar (and other) transporter
IOGPPLLF_01750 2.1e-199 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IOGPPLLF_01751 4e-83 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IOGPPLLF_01752 2.3e-184 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
IOGPPLLF_01753 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
IOGPPLLF_01754 9.6e-275 aroP E aromatic amino acid transport protein AroP K03293
IOGPPLLF_01755 7e-101 K Transcriptional regulator C-terminal region
IOGPPLLF_01756 2.6e-129 V ABC transporter
IOGPPLLF_01757 0.0 V FtsX-like permease family
IOGPPLLF_01758 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOGPPLLF_01759 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOGPPLLF_01760 7.6e-39 E ABC transporter
IOGPPLLF_01761 1.7e-99 bcp 1.11.1.15 O Redoxin
IOGPPLLF_01762 2e-156 S Virulence factor BrkB
IOGPPLLF_01763 2.1e-41 XAC3035 O Glutaredoxin
IOGPPLLF_01764 4.8e-48
IOGPPLLF_01766 8.1e-99 L Restriction endonuclease NotI
IOGPPLLF_01767 9.1e-82
IOGPPLLF_01768 2.1e-23 L Transposase, Mutator family
IOGPPLLF_01769 4.1e-189 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOGPPLLF_01770 1.2e-152 sapF E ATPases associated with a variety of cellular activities
IOGPPLLF_01771 5.7e-141 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
IOGPPLLF_01772 5.8e-164 EP Binding-protein-dependent transport system inner membrane component
IOGPPLLF_01773 1.4e-170 P Binding-protein-dependent transport system inner membrane component
IOGPPLLF_01774 4.6e-310 E ABC transporter, substrate-binding protein, family 5
IOGPPLLF_01775 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IOGPPLLF_01776 2e-277 G Bacterial extracellular solute-binding protein
IOGPPLLF_01777 3.3e-62 G carbohydrate transport
IOGPPLLF_01778 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
IOGPPLLF_01779 2.6e-126 G ABC transporter permease
IOGPPLLF_01780 2.9e-190 K Periplasmic binding protein domain
IOGPPLLF_01781 1.4e-17 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IOGPPLLF_01782 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
IOGPPLLF_01784 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOGPPLLF_01785 3.8e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IOGPPLLF_01786 1e-273 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
IOGPPLLF_01787 2.4e-127 XK27_08050 O prohibitin homologues
IOGPPLLF_01788 4.5e-244 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
IOGPPLLF_01789 1.2e-233 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
IOGPPLLF_01790 2.1e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
IOGPPLLF_01791 2.4e-218 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IOGPPLLF_01792 0.0 macB_2 V ATPases associated with a variety of cellular activities
IOGPPLLF_01793 0.0 ctpE P E1-E2 ATPase
IOGPPLLF_01794 1.3e-54 racA K MerR, DNA binding
IOGPPLLF_01795 3.2e-197 yghZ C Aldo/keto reductase family
IOGPPLLF_01796 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
IOGPPLLF_01797 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
IOGPPLLF_01798 5.5e-149 map 3.4.11.18 E Methionine aminopeptidase
IOGPPLLF_01799 7.9e-123 S Short repeat of unknown function (DUF308)
IOGPPLLF_01800 0.0 pepO 3.4.24.71 O Peptidase family M13
IOGPPLLF_01801 7.9e-120 L Single-strand binding protein family
IOGPPLLF_01802 3e-114
IOGPPLLF_01803 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOGPPLLF_01804 4.2e-272 recD2 3.6.4.12 L PIF1-like helicase
IOGPPLLF_01805 1.5e-160 supH S Sucrose-6F-phosphate phosphohydrolase
IOGPPLLF_01806 9.1e-121 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
IOGPPLLF_01807 3.2e-57 KT Transcriptional regulatory protein, C terminal
IOGPPLLF_01808 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
IOGPPLLF_01809 4.1e-289 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IOGPPLLF_01810 8e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
IOGPPLLF_01811 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
IOGPPLLF_01812 1e-49 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
IOGPPLLF_01813 2.5e-186 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOGPPLLF_01814 1.2e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOGPPLLF_01815 3.9e-36 rpmE J Binds the 23S rRNA
IOGPPLLF_01817 9e-195 K helix_turn_helix, arabinose operon control protein
IOGPPLLF_01818 2.6e-163 glcU G Sugar transport protein
IOGPPLLF_01819 3.4e-178 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
IOGPPLLF_01820 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
IOGPPLLF_01821 1.5e-108
IOGPPLLF_01822 2.4e-128 S Metallo-beta-lactamase domain protein
IOGPPLLF_01823 4.7e-137 L IstB-like ATP binding protein
IOGPPLLF_01824 1.3e-245 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)