ORF_ID e_value Gene_name EC_number CAZy COGs Description
KCBBIPOP_00002 1.1e-25 S Bacteriocin class II with double-glycine leader peptide
KCBBIPOP_00003 0.0 mdlB V abc transporter atp-binding protein
KCBBIPOP_00004 0.0 mdlA V abc transporter atp-binding protein
KCBBIPOP_00007 1.3e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
KCBBIPOP_00008 3.9e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KCBBIPOP_00009 1.7e-62 yutD J protein conserved in bacteria
KCBBIPOP_00010 9.6e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KCBBIPOP_00013 3.6e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KCBBIPOP_00014 3.5e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCBBIPOP_00015 0.0 ftsI 3.4.16.4 M penicillin-binding protein
KCBBIPOP_00016 2.4e-45 ftsL D cell division protein FtsL
KCBBIPOP_00017 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KCBBIPOP_00018 3.7e-25
KCBBIPOP_00021 5e-69 yhaI J Protein of unknown function (DUF805)
KCBBIPOP_00022 4.4e-62 yhaI S Protein of unknown function (DUF805)
KCBBIPOP_00023 1.4e-223 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCBBIPOP_00024 1.3e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KCBBIPOP_00025 8.4e-253 XK27_00765
KCBBIPOP_00026 6.8e-133 ecsA_2 V abc transporter atp-binding protein
KCBBIPOP_00027 3.1e-125 S Protein of unknown function (DUF554)
KCBBIPOP_00028 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KCBBIPOP_00029 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KCBBIPOP_00030 5.2e-243 2.7.13.3 T protein histidine kinase activity
KCBBIPOP_00031 9.4e-234 dcuS 2.7.13.3 T protein histidine kinase activity
KCBBIPOP_00032 8.9e-14
KCBBIPOP_00035 1.3e-145 V Psort location CytoplasmicMembrane, score
KCBBIPOP_00037 9.2e-300 O MreB/Mbl protein
KCBBIPOP_00038 6.3e-112 liaI S membrane
KCBBIPOP_00039 6.8e-75 XK27_02470 K LytTr DNA-binding domain protein
KCBBIPOP_00040 0.0 KT response to antibiotic
KCBBIPOP_00041 3.4e-129 yebC M Membrane
KCBBIPOP_00042 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
KCBBIPOP_00043 2e-180 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KCBBIPOP_00045 2.9e-31 yozG K Transcriptional regulator
KCBBIPOP_00049 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCBBIPOP_00050 5.2e-201 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KCBBIPOP_00051 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KCBBIPOP_00052 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCBBIPOP_00053 3.3e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCBBIPOP_00054 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KCBBIPOP_00056 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCBBIPOP_00057 1.2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
KCBBIPOP_00058 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KCBBIPOP_00059 4.7e-287 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
KCBBIPOP_00060 2.4e-178 scrR K Transcriptional regulator
KCBBIPOP_00061 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCBBIPOP_00062 1.7e-61 yqhY S protein conserved in bacteria
KCBBIPOP_00063 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCBBIPOP_00064 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
KCBBIPOP_00065 1.7e-188 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
KCBBIPOP_00072 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
KCBBIPOP_00073 1.4e-107 S Domain of unknown function (DUF1803)
KCBBIPOP_00074 7.8e-102 ygaC J Belongs to the UPF0374 family
KCBBIPOP_00075 2e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
KCBBIPOP_00076 1.4e-248 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCBBIPOP_00077 1.4e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
KCBBIPOP_00078 8.2e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
KCBBIPOP_00079 1.8e-113 S HAD hydrolase, family IA, variant 3
KCBBIPOP_00080 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
KCBBIPOP_00081 5.2e-72 marR K Transcriptional regulator, MarR family
KCBBIPOP_00082 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCBBIPOP_00083 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCBBIPOP_00084 2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
KCBBIPOP_00085 5.2e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KCBBIPOP_00086 6.9e-125 IQ reductase
KCBBIPOP_00087 2.2e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KCBBIPOP_00088 5.2e-52 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KCBBIPOP_00089 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KCBBIPOP_00090 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KCBBIPOP_00091 9.5e-158 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCBBIPOP_00092 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KCBBIPOP_00093 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KCBBIPOP_00094 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
KCBBIPOP_00095 4e-112 fruR K transcriptional
KCBBIPOP_00096 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KCBBIPOP_00097 0.0 fruA 2.7.1.202 G phosphotransferase system
KCBBIPOP_00098 1.1e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCBBIPOP_00099 1.2e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KCBBIPOP_00101 8e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KCBBIPOP_00102 1.7e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCBBIPOP_00103 1.1e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KCBBIPOP_00104 6.7e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KCBBIPOP_00105 7.1e-95 2.3.1.128 K acetyltransferase
KCBBIPOP_00106 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KCBBIPOP_00107 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KCBBIPOP_00108 4.5e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCBBIPOP_00109 5e-63 WQ51_03320 S cog cog4835
KCBBIPOP_00110 1.4e-150 XK27_08360 S EDD domain protein, DegV family
KCBBIPOP_00111 6.3e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KCBBIPOP_00112 1.6e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KCBBIPOP_00113 0.0 yfmR S abc transporter atp-binding protein
KCBBIPOP_00114 1e-26 U response to pH
KCBBIPOP_00115 8.1e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
KCBBIPOP_00116 2.9e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KCBBIPOP_00117 4.1e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KCBBIPOP_00118 4e-282 S Psort location CytoplasmicMembrane, score
KCBBIPOP_00119 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KCBBIPOP_00120 3.3e-74 K DNA-binding transcription factor activity
KCBBIPOP_00121 0.0 lmrA1 V abc transporter atp-binding protein
KCBBIPOP_00122 0.0 lmrA2 V abc transporter atp-binding protein
KCBBIPOP_00123 3.3e-112 K Acetyltransferase (GNAT) family
KCBBIPOP_00124 5.1e-113 2.7.6.5 S Region found in RelA / SpoT proteins
KCBBIPOP_00125 1.7e-117 T response regulator
KCBBIPOP_00126 8.5e-213 sptS 2.7.13.3 T Histidine kinase
KCBBIPOP_00127 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KCBBIPOP_00128 1.7e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KCBBIPOP_00129 4.5e-160 cvfB S Protein conserved in bacteria
KCBBIPOP_00130 3.7e-34 yozE S Belongs to the UPF0346 family
KCBBIPOP_00131 6e-137 sip M LysM domain protein
KCBBIPOP_00132 5.7e-189 phoH T phosphate starvation-inducible protein PhoH
KCBBIPOP_00137 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCBBIPOP_00138 7.4e-169 S Conjugative transposon protein TcpC
KCBBIPOP_00139 8.3e-128 D Domain of unknown function DUF87
KCBBIPOP_00140 1e-63 S Bacterial protein of unknown function (DUF961)
KCBBIPOP_00141 2.3e-53 S Bacterial protein of unknown function (DUF961)
KCBBIPOP_00143 1.5e-66
KCBBIPOP_00144 1e-231 S dextransucrase activity
KCBBIPOP_00145 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KCBBIPOP_00146 0.0 S dextransucrase activity
KCBBIPOP_00147 0.0 S dextransucrase activity
KCBBIPOP_00148 0.0 S dextransucrase activity
KCBBIPOP_00149 4.5e-83 M Putative cell wall binding repeat
KCBBIPOP_00150 0.0 M Putative cell wall binding repeat
KCBBIPOP_00151 1.6e-240 tcdB S dextransucrase activity
KCBBIPOP_00152 0.0 S dextransucrase activity
KCBBIPOP_00153 1.4e-104 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KCBBIPOP_00154 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KCBBIPOP_00155 0.0 M Putative cell wall binding repeat
KCBBIPOP_00156 0.0 M Putative cell wall binding repeat
KCBBIPOP_00157 0.0 S dextransucrase activity
KCBBIPOP_00158 0.0 S dextransucrase activity
KCBBIPOP_00160 3e-131 XK27_00785 S CAAX protease self-immunity
KCBBIPOP_00161 9.3e-240 EGP Major facilitator Superfamily
KCBBIPOP_00162 1.8e-66 rmaI K Transcriptional regulator, MarR family
KCBBIPOP_00163 6.7e-88 maa 2.3.1.79 GK Maltose O-acetyltransferase
KCBBIPOP_00164 6.1e-137 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
KCBBIPOP_00165 0.0 3.5.1.28 M domain protein
KCBBIPOP_00166 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KCBBIPOP_00167 1.5e-109 K Helix-turn-helix domain, rpiR family
KCBBIPOP_00168 2.7e-17 3.2.1.51 GH95 U LPXTG cell wall anchor motif
KCBBIPOP_00169 2.7e-51 ywrO S general stress protein
KCBBIPOP_00170 2.2e-165 K sequence-specific DNA binding
KCBBIPOP_00171 7.2e-103 S ABC-2 family transporter protein
KCBBIPOP_00172 4e-153 V ABC transporter, ATP-binding protein
KCBBIPOP_00173 1.6e-163 K sequence-specific DNA binding
KCBBIPOP_00174 2.1e-80 3.4.21.89 S RDD family
KCBBIPOP_00175 1.9e-22 yjlA EG membrane
KCBBIPOP_00176 3.5e-121 yjlA EG membrane
KCBBIPOP_00177 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
KCBBIPOP_00178 7.6e-147 sdaAA 4.3.1.17 E L-serine dehydratase
KCBBIPOP_00179 1.8e-119 sdaAB 4.3.1.17 E L-serine dehydratase
KCBBIPOP_00180 1.1e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KCBBIPOP_00181 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KCBBIPOP_00182 1.3e-271 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCBBIPOP_00183 3.1e-92 pat 2.3.1.183 M acetyltransferase
KCBBIPOP_00184 3.7e-293 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCBBIPOP_00185 4.8e-122 alkD L Dna alkylation repair
KCBBIPOP_00186 1.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCBBIPOP_00187 1.7e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCBBIPOP_00188 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KCBBIPOP_00189 0.0 smc D Required for chromosome condensation and partitioning
KCBBIPOP_00190 1e-93 S Protein of unknown function (DUF3278)
KCBBIPOP_00191 2.9e-22 WQ51_00220 K Helix-turn-helix domain
KCBBIPOP_00192 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KCBBIPOP_00193 1.7e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KCBBIPOP_00194 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KCBBIPOP_00196 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
KCBBIPOP_00197 2e-236 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KCBBIPOP_00199 9.4e-81 S ECF-type riboflavin transporter, S component
KCBBIPOP_00200 1.2e-144 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KCBBIPOP_00201 6.1e-83 XK27_01265 S ECF-type riboflavin transporter, S component
KCBBIPOP_00202 1.1e-294 yfmM S abc transporter atp-binding protein
KCBBIPOP_00203 1.4e-256 noxE P NADH oxidase
KCBBIPOP_00204 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KCBBIPOP_00205 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCBBIPOP_00206 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
KCBBIPOP_00207 2.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
KCBBIPOP_00208 7.6e-164 ypuA S secreted protein
KCBBIPOP_00209 2.7e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
KCBBIPOP_00210 4.4e-45 rpmE2 J 50S ribosomal protein L31
KCBBIPOP_00211 3.4e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KCBBIPOP_00212 1e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
KCBBIPOP_00213 1.5e-154 gst O Glutathione S-transferase
KCBBIPOP_00214 1.1e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KCBBIPOP_00215 1.9e-109 tdk 2.7.1.21 F thymidine kinase
KCBBIPOP_00216 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCBBIPOP_00217 7e-142 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KCBBIPOP_00218 4.2e-104 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KCBBIPOP_00219 4.6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KCBBIPOP_00220 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
KCBBIPOP_00221 6.4e-100 pvaA M lytic transglycosylase activity
KCBBIPOP_00222 9.4e-290 yfiB1 V abc transporter atp-binding protein
KCBBIPOP_00223 0.0 XK27_10035 V abc transporter atp-binding protein
KCBBIPOP_00224 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KCBBIPOP_00225 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KCBBIPOP_00228 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KCBBIPOP_00230 1e-20 L the current gene model (or a revised gene model) may contain a frame shift
KCBBIPOP_00231 5.3e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
KCBBIPOP_00232 5.8e-137 yfeJ 6.3.5.2 F glutamine amidotransferase
KCBBIPOP_00233 2.3e-181 clcA_2 P Chloride transporter, ClC family
KCBBIPOP_00234 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KCBBIPOP_00235 5.5e-95 S Protein of unknown function (DUF1697)
KCBBIPOP_00236 5.2e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KCBBIPOP_00237 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KCBBIPOP_00238 2.5e-253 V Glucan-binding protein C
KCBBIPOP_00239 1.4e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KCBBIPOP_00240 1.1e-222 XK27_05470 E Methionine synthase
KCBBIPOP_00241 2.1e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KCBBIPOP_00242 4.7e-236 T PhoQ Sensor
KCBBIPOP_00243 1.5e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCBBIPOP_00244 2e-149 S TraX protein
KCBBIPOP_00246 3.8e-51 V ABC-2 family transporter protein
KCBBIPOP_00247 4.6e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
KCBBIPOP_00248 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCBBIPOP_00249 4.6e-157 dprA LU DNA protecting protein DprA
KCBBIPOP_00250 3.7e-160 GK ROK family
KCBBIPOP_00251 3.8e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCBBIPOP_00252 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KCBBIPOP_00253 1.2e-126 K DNA-binding helix-turn-helix protein
KCBBIPOP_00254 7.7e-91 niaR S small molecule binding protein (contains 3H domain)
KCBBIPOP_00255 4.5e-86
KCBBIPOP_00256 1e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCBBIPOP_00257 8.4e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KCBBIPOP_00258 2.7e-126 gntR1 K transcriptional
KCBBIPOP_00259 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KCBBIPOP_00260 3.7e-97
KCBBIPOP_00261 2.4e-56 S ABC-2 type transporter
KCBBIPOP_00262 2.9e-162 V AAA domain, putative AbiEii toxin, Type IV TA system
KCBBIPOP_00263 3e-184 L PFAM Integrase, catalytic core
KCBBIPOP_00264 5.1e-107 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KCBBIPOP_00265 5e-31 adhP 1.1.1.1 P alcohol dehydrogenase
KCBBIPOP_00266 9.3e-40 adhP 1.1.1.1 P alcohol dehydrogenase
KCBBIPOP_00267 3e-57 adhP 1.1.1.1 P alcohol dehydrogenase
KCBBIPOP_00268 1.9e-46
KCBBIPOP_00269 2.6e-51
KCBBIPOP_00270 2.1e-271 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCBBIPOP_00271 4.9e-159 aatB ET ABC transporter substrate-binding protein
KCBBIPOP_00272 4e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCBBIPOP_00273 1.4e-105 artQ P ABC transporter (Permease
KCBBIPOP_00274 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
KCBBIPOP_00275 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KCBBIPOP_00276 2.9e-165 cpsY K Transcriptional regulator
KCBBIPOP_00277 1.3e-128 mur1 3.4.17.14, 3.5.1.28 NU muramidase
KCBBIPOP_00278 5.5e-173 yeiH S Membrane
KCBBIPOP_00280 2.6e-09
KCBBIPOP_00281 1.4e-167 L Transposase
KCBBIPOP_00282 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KCBBIPOP_00283 8.4e-138 divIVA D Cell division initiation protein
KCBBIPOP_00284 5e-145 ylmH S conserved protein, contains S4-like domain
KCBBIPOP_00285 6.5e-30 yggT D integral membrane protein
KCBBIPOP_00286 3.2e-101 sepF D cell septum assembly
KCBBIPOP_00287 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KCBBIPOP_00288 1.7e-238 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KCBBIPOP_00289 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KCBBIPOP_00290 2.2e-133 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KCBBIPOP_00291 8.6e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCBBIPOP_00292 2.1e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KCBBIPOP_00294 0.0 typA T GTP-binding protein TypA
KCBBIPOP_00295 1.4e-178 glk 2.7.1.2 G Glucokinase
KCBBIPOP_00296 2.4e-27 yqgQ S protein conserved in bacteria
KCBBIPOP_00297 5.2e-83 perR P Belongs to the Fur family
KCBBIPOP_00298 9.3e-92 dps P Belongs to the Dps family
KCBBIPOP_00299 1.7e-114 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
KCBBIPOP_00300 3.6e-172 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
KCBBIPOP_00301 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
KCBBIPOP_00302 1.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
KCBBIPOP_00303 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KCBBIPOP_00304 2e-62 S Domain of unknown function (DUF4430)
KCBBIPOP_00305 6.7e-73 S Psort location CytoplasmicMembrane, score
KCBBIPOP_00306 7.5e-124 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
KCBBIPOP_00307 2.1e-133 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
KCBBIPOP_00308 1.9e-164 sitA P Belongs to the bacterial solute-binding protein 9 family
KCBBIPOP_00309 9.4e-118 sirR K iron dependent repressor
KCBBIPOP_00310 4.6e-131 htpX O Belongs to the peptidase M48B family
KCBBIPOP_00311 3.8e-91 lemA S LemA family
KCBBIPOP_00312 2.7e-172 spd F DNA RNA non-specific endonuclease
KCBBIPOP_00313 0.0 2.4.1.21 GT5 M Right handed beta helix region
KCBBIPOP_00314 4.5e-155 S double-stranded DNA endodeoxyribonuclease activity
KCBBIPOP_00315 4.3e-305 hsdM 2.1.1.72 V type I restriction-modification system
KCBBIPOP_00316 4.1e-125 S Protein conserved in bacteria
KCBBIPOP_00317 6.4e-197 E Psort location Cytoplasmic, score
KCBBIPOP_00318 4e-93 3.1.21.3 V Type I restriction modification DNA specificity domain
KCBBIPOP_00319 1.4e-107 L Reverse transcriptase (RNA-dependent DNA polymerase)
KCBBIPOP_00320 7.3e-91
KCBBIPOP_00321 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KCBBIPOP_00322 1.7e-45 K Helix-turn-helix domain
KCBBIPOP_00323 4.4e-45 S Phage derived protein Gp49-like (DUF891)
KCBBIPOP_00324 1.4e-133 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KCBBIPOP_00325 4.4e-211 MA20_36090 S Protein of unknown function (DUF2974)
KCBBIPOP_00326 2.8e-111 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCBBIPOP_00327 4.6e-157 5.2.1.8 G hydrolase
KCBBIPOP_00328 7.8e-27 P Hemerythrin HHE cation binding domain protein
KCBBIPOP_00329 5.8e-142 XK27_00880 3.4.17.14, 3.5.1.28 M Glycosyl hydrolase, family 25
KCBBIPOP_00330 7.5e-62 XK27_08085
KCBBIPOP_00331 4.7e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KCBBIPOP_00332 1.6e-137 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KCBBIPOP_00333 1.6e-117 ylfI S tigr01906
KCBBIPOP_00334 5.2e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KCBBIPOP_00335 2.2e-142 fat 3.1.2.21 I Acyl-ACP thioesterase
KCBBIPOP_00336 8.2e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
KCBBIPOP_00337 3.7e-30 KT response to antibiotic
KCBBIPOP_00339 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KCBBIPOP_00340 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KCBBIPOP_00341 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KCBBIPOP_00342 4.3e-258 S phospholipase Carboxylesterase
KCBBIPOP_00343 1.1e-200 yurR 1.4.5.1 E oxidoreductase
KCBBIPOP_00344 8e-146 zupT P Mediates zinc uptake. May also transport other divalent cations
KCBBIPOP_00345 2.2e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KCBBIPOP_00346 2.6e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
KCBBIPOP_00347 3.3e-63 gtrA S GtrA-like protein
KCBBIPOP_00348 1.3e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCBBIPOP_00349 8.4e-163 ybbR S Protein conserved in bacteria
KCBBIPOP_00350 1.8e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KCBBIPOP_00351 1.2e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
KCBBIPOP_00352 8.7e-150 cobQ S glutamine amidotransferase
KCBBIPOP_00353 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KCBBIPOP_00354 1.8e-130 pip 1.11.1.10 S Alpha beta hydrolase
KCBBIPOP_00355 1.6e-39 MA20_06245 S yiaA/B two helix domain
KCBBIPOP_00356 0.0 uup S abc transporter atp-binding protein
KCBBIPOP_00357 5.2e-113 udk 2.7.1.48 F Cytidine monophosphokinase
KCBBIPOP_00358 1.2e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
KCBBIPOP_00359 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
KCBBIPOP_00360 2.7e-153 XK27_05675 S Esterase
KCBBIPOP_00361 6.1e-162 XK27_05670 S Putative esterase
KCBBIPOP_00362 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KCBBIPOP_00363 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCBBIPOP_00364 3e-38 ptsH G phosphocarrier protein Hpr
KCBBIPOP_00365 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
KCBBIPOP_00366 1.3e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
KCBBIPOP_00367 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KCBBIPOP_00368 2.2e-34 nrdH O Glutaredoxin
KCBBIPOP_00369 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCBBIPOP_00370 4.2e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCBBIPOP_00372 8.3e-290 ahpF O alkyl hydroperoxide reductase
KCBBIPOP_00373 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
KCBBIPOP_00374 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
KCBBIPOP_00375 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCBBIPOP_00376 1.2e-82 S Putative small multi-drug export protein
KCBBIPOP_00377 4.8e-76 ctsR K Belongs to the CtsR family
KCBBIPOP_00378 0.0 clpC O Belongs to the ClpA ClpB family
KCBBIPOP_00379 2e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCBBIPOP_00380 6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCBBIPOP_00381 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KCBBIPOP_00382 5.7e-138 S SseB protein N-terminal domain
KCBBIPOP_00383 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
KCBBIPOP_00385 8.1e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCBBIPOP_00386 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KCBBIPOP_00388 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCBBIPOP_00389 2.7e-91 yacP S RNA-binding protein containing a PIN domain
KCBBIPOP_00390 1.4e-153 degV S DegV family
KCBBIPOP_00392 5.1e-22 K Transcriptional
KCBBIPOP_00393 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KCBBIPOP_00394 7.3e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KCBBIPOP_00395 3.4e-18
KCBBIPOP_00396 1.5e-29 K Helix-turn-helix domain
KCBBIPOP_00397 6e-85
KCBBIPOP_00398 3.2e-139 srtB 3.4.22.70 S sortase, SrtB family
KCBBIPOP_00399 2.2e-232 capA M Bacterial capsule synthesis protein
KCBBIPOP_00400 6.1e-39 gcvR T UPF0237 protein
KCBBIPOP_00401 2.3e-243 XK27_08635 S UPF0210 protein
KCBBIPOP_00402 2.5e-132 ais G Phosphoglycerate mutase
KCBBIPOP_00403 1.8e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KCBBIPOP_00404 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
KCBBIPOP_00405 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KCBBIPOP_00406 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCBBIPOP_00407 8.9e-307 dnaK O Heat shock 70 kDa protein
KCBBIPOP_00408 1e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KCBBIPOP_00409 1.7e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KCBBIPOP_00410 7.3e-138 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
KCBBIPOP_00411 1.5e-80 hmpT S cog cog4720
KCBBIPOP_00412 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KCBBIPOP_00413 3.8e-91 panT S Psort location CytoplasmicMembrane, score
KCBBIPOP_00414 1.9e-93 panT S ECF transporter, substrate-specific component
KCBBIPOP_00415 4.8e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCBBIPOP_00416 1e-114 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
KCBBIPOP_00417 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KCBBIPOP_00418 2.1e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCBBIPOP_00419 6.6e-241 T PhoQ Sensor
KCBBIPOP_00420 1e-29 rpsT J Binds directly to 16S ribosomal RNA
KCBBIPOP_00421 3e-170 coaA 2.7.1.33 F Pantothenic acid kinase
KCBBIPOP_00422 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
KCBBIPOP_00423 1.1e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KCBBIPOP_00424 3.9e-108 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KCBBIPOP_00425 1.3e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KCBBIPOP_00426 1.1e-192 tcsA S membrane
KCBBIPOP_00427 2.9e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KCBBIPOP_00428 1.3e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
KCBBIPOP_00429 9.1e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
KCBBIPOP_00430 2.8e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KCBBIPOP_00431 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KCBBIPOP_00432 1.1e-81 ypmB S Protein conserved in bacteria
KCBBIPOP_00433 2.8e-213 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KCBBIPOP_00434 2.4e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KCBBIPOP_00435 1.4e-18
KCBBIPOP_00436 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
KCBBIPOP_00437 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KCBBIPOP_00438 7.4e-82 queD 4.1.2.50, 4.2.3.12 H synthase
KCBBIPOP_00439 1e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KCBBIPOP_00440 1.6e-93 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KCBBIPOP_00441 1.3e-199 D nuclear chromosome segregation
KCBBIPOP_00442 3.7e-137 yejC S cyclic nucleotide-binding protein
KCBBIPOP_00443 7e-164 rapZ S Displays ATPase and GTPase activities
KCBBIPOP_00444 2.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KCBBIPOP_00445 8.2e-160 whiA K May be required for sporulation
KCBBIPOP_00446 1.5e-274 pepD E Dipeptidase
KCBBIPOP_00447 2.3e-145 XK27_10720 D peptidase activity
KCBBIPOP_00448 4e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
KCBBIPOP_00449 1.5e-290 norB P Major facilitator superfamily
KCBBIPOP_00450 3.6e-94 tetR K transcriptional regulator
KCBBIPOP_00451 1.9e-155 S Domain of unknown function (DUF4300)
KCBBIPOP_00452 7.3e-130 V CAAX protease self-immunity
KCBBIPOP_00453 1.1e-155 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCBBIPOP_00454 1.2e-135 fecE 3.6.3.34 HP ABC transporter
KCBBIPOP_00455 5.5e-165 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KCBBIPOP_00456 1.6e-123 ybbA S Putative esterase
KCBBIPOP_00457 1.8e-83 Q Methyltransferase domain
KCBBIPOP_00458 8.5e-78 K TetR family transcriptional regulator
KCBBIPOP_00459 5.8e-49
KCBBIPOP_00460 5.9e-124 V CAAX protease self-immunity
KCBBIPOP_00461 1.5e-10
KCBBIPOP_00462 8.4e-19 S Bacterial lipoprotein
KCBBIPOP_00463 4.1e-60 S Protein of unknown function (DUF1722)
KCBBIPOP_00464 2.6e-64 yqeB S Pyrimidine dimer DNA glycosylase
KCBBIPOP_00466 2e-49
KCBBIPOP_00467 5.2e-94 S CAAX protease self-immunity
KCBBIPOP_00468 3.3e-115 estA E GDSL-like Lipase/Acylhydrolase
KCBBIPOP_00469 1.4e-102
KCBBIPOP_00470 5.8e-289 sulP P Sulfate permease and related transporters (MFS superfamily)
KCBBIPOP_00471 3.8e-148 ycgQ S TIGR03943 family
KCBBIPOP_00472 7.1e-156 XK27_03015 S permease
KCBBIPOP_00474 0.0 yhgF K Transcriptional accessory protein
KCBBIPOP_00475 3.9e-83 ydcK S Belongs to the SprT family
KCBBIPOP_00476 2.2e-41 pspC KT PspC domain
KCBBIPOP_00477 2e-166 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KCBBIPOP_00478 2.1e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KCBBIPOP_00479 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KCBBIPOP_00480 1.6e-68 ytxH S General stress protein
KCBBIPOP_00482 6.8e-178 yegQ O Peptidase U32
KCBBIPOP_00483 1.7e-251 yegQ O Peptidase U32
KCBBIPOP_00484 1e-88 bioY S biotin synthase
KCBBIPOP_00486 1.8e-33 XK27_12190 S protein conserved in bacteria
KCBBIPOP_00487 3e-235 mntH P H( )-stimulated, divalent metal cation uptake system
KCBBIPOP_00489 7.5e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KCBBIPOP_00490 3.9e-136 M LysM domain
KCBBIPOP_00491 8.4e-23
KCBBIPOP_00492 5.9e-88 sigH K DNA-templated transcription, initiation
KCBBIPOP_00493 2.8e-140 ykuT M mechanosensitive ion channel
KCBBIPOP_00494 1.8e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KCBBIPOP_00495 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KCBBIPOP_00496 4.9e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KCBBIPOP_00497 6.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
KCBBIPOP_00498 1.1e-77 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
KCBBIPOP_00499 7.2e-83 XK27_02675 K Acetyltransferase GNAT Family
KCBBIPOP_00500 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
KCBBIPOP_00501 2e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KCBBIPOP_00502 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KCBBIPOP_00503 5e-81 nrdI F Belongs to the NrdI family
KCBBIPOP_00504 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCBBIPOP_00505 4.7e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KCBBIPOP_00506 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KCBBIPOP_00507 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCBBIPOP_00508 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KCBBIPOP_00509 3.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KCBBIPOP_00510 9.6e-198 yhjX P Major Facilitator
KCBBIPOP_00511 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KCBBIPOP_00512 1.4e-72 V VanZ like family
KCBBIPOP_00513 9.9e-179 D nuclear chromosome segregation
KCBBIPOP_00514 2.2e-123 glnQ E abc transporter atp-binding protein
KCBBIPOP_00515 1.6e-272 glnP P ABC transporter
KCBBIPOP_00516 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KCBBIPOP_00517 3.1e-17 S Protein of unknown function (DUF3021)
KCBBIPOP_00518 5.9e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KCBBIPOP_00519 3.9e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
KCBBIPOP_00520 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KCBBIPOP_00521 2e-233 sufD O assembly protein SufD
KCBBIPOP_00522 1.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCBBIPOP_00523 1.6e-73 nifU C SUF system FeS assembly protein, NifU family
KCBBIPOP_00524 1.1e-272 sufB O assembly protein SufB
KCBBIPOP_00525 2.3e-311 oppA E ABC transporter substrate-binding protein
KCBBIPOP_00526 9.7e-161 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCBBIPOP_00527 1.9e-165 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCBBIPOP_00528 1.9e-197 oppD P Belongs to the ABC transporter superfamily
KCBBIPOP_00529 5.8e-169 oppF P Belongs to the ABC transporter superfamily
KCBBIPOP_00530 3.6e-26
KCBBIPOP_00531 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KCBBIPOP_00532 1.1e-181 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCBBIPOP_00533 2.6e-71 adcR K transcriptional
KCBBIPOP_00534 9.2e-135 adcC P ABC transporter, ATP-binding protein
KCBBIPOP_00535 9.6e-128 adcB P ABC transporter (Permease
KCBBIPOP_00536 1.3e-160 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KCBBIPOP_00537 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KCBBIPOP_00538 1.4e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
KCBBIPOP_00539 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
KCBBIPOP_00540 2.1e-149 Z012_04635 K sequence-specific DNA binding
KCBBIPOP_00541 6.5e-282 V ABC transporter
KCBBIPOP_00542 9.4e-127 yeeN K transcriptional regulatory protein
KCBBIPOP_00543 3.1e-48 yajC U protein transport
KCBBIPOP_00544 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCBBIPOP_00545 8.5e-145 cdsA 2.7.7.41 S Belongs to the CDS family
KCBBIPOP_00546 4.7e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KCBBIPOP_00547 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KCBBIPOP_00548 0.0 WQ51_06230 S ABC transporter
KCBBIPOP_00549 3e-142 cmpC S abc transporter atp-binding protein
KCBBIPOP_00550 8.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KCBBIPOP_00551 2.4e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KCBBIPOP_00553 5.5e-44
KCBBIPOP_00554 5.8e-55 S TM2 domain
KCBBIPOP_00555 5.6e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KCBBIPOP_00556 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCBBIPOP_00557 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KCBBIPOP_00558 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
KCBBIPOP_00559 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
KCBBIPOP_00560 2.4e-73 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
KCBBIPOP_00561 5.8e-149 cof S Sucrose-6F-phosphate phosphohydrolase
KCBBIPOP_00562 4.8e-137 glcR K transcriptional regulator (DeoR family)
KCBBIPOP_00563 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCBBIPOP_00564 1e-73 K transcriptional
KCBBIPOP_00565 2.8e-235 S COG1073 Hydrolases of the alpha beta superfamily
KCBBIPOP_00566 1.3e-35 yjdF S Protein of unknown function (DUF2992)
KCBBIPOP_00567 2.1e-149 cylA V abc transporter atp-binding protein
KCBBIPOP_00568 9e-129 cylB V ABC-2 type transporter
KCBBIPOP_00569 9e-75 K COG3279 Response regulator of the LytR AlgR family
KCBBIPOP_00570 8.9e-32 S Protein of unknown function (DUF3021)
KCBBIPOP_00571 1.1e-116 mta K Transcriptional
KCBBIPOP_00572 3.3e-121 yhcA V abc transporter atp-binding protein
KCBBIPOP_00573 1.6e-217 macB_2 V FtsX-like permease family
KCBBIPOP_00574 1.9e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KCBBIPOP_00575 4.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KCBBIPOP_00576 1.1e-77 yhaI S Protein of unknown function (DUF805)
KCBBIPOP_00577 1.6e-257 pepC 3.4.22.40 E aminopeptidase
KCBBIPOP_00578 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCBBIPOP_00579 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KCBBIPOP_00580 8e-96 ypsA S Belongs to the UPF0398 family
KCBBIPOP_00581 1.1e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KCBBIPOP_00582 1.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KCBBIPOP_00583 1.1e-286 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KCBBIPOP_00584 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KCBBIPOP_00585 9.6e-23
KCBBIPOP_00586 4.7e-257 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KCBBIPOP_00587 4.1e-89 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
KCBBIPOP_00588 2.1e-306 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCBBIPOP_00589 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KCBBIPOP_00590 3.4e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KCBBIPOP_00591 9.2e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KCBBIPOP_00592 5.5e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCBBIPOP_00593 2.5e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
KCBBIPOP_00594 1.2e-102 ybhL S Belongs to the BI1 family
KCBBIPOP_00595 8.4e-13 ycdA S Domain of unknown function (DUF4352)
KCBBIPOP_00596 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KCBBIPOP_00597 1.4e-90 K transcriptional regulator
KCBBIPOP_00598 1.6e-36 yneF S UPF0154 protein
KCBBIPOP_00599 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KCBBIPOP_00600 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KCBBIPOP_00601 1.7e-98 XK27_09740 S Phosphoesterase
KCBBIPOP_00602 8.3e-87 ykuL S CBS domain
KCBBIPOP_00603 1e-134 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KCBBIPOP_00604 1.8e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCBBIPOP_00605 6.5e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCBBIPOP_00606 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCBBIPOP_00607 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
KCBBIPOP_00608 4.9e-260 trkH P Cation transport protein
KCBBIPOP_00609 1.2e-247 trkA P Potassium transporter peripheral membrane component
KCBBIPOP_00610 6.1e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KCBBIPOP_00611 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KCBBIPOP_00612 2.8e-106 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
KCBBIPOP_00613 3e-154 K sequence-specific DNA binding
KCBBIPOP_00614 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCBBIPOP_00615 6.4e-54 yhaI L Membrane
KCBBIPOP_00616 2.8e-38 S Domain of unknown function (DUF4173)
KCBBIPOP_00617 6.8e-95 ureI S AmiS/UreI family transporter
KCBBIPOP_00618 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KCBBIPOP_00619 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KCBBIPOP_00620 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KCBBIPOP_00621 6.6e-78 ureE O enzyme active site formation
KCBBIPOP_00622 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KCBBIPOP_00623 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KCBBIPOP_00624 4e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KCBBIPOP_00625 1.3e-176 cbiM P biosynthesis protein CbiM
KCBBIPOP_00626 1.1e-136 P cobalt transport protein
KCBBIPOP_00627 8.2e-131 cbiO P ABC transporter
KCBBIPOP_00628 6.3e-138 ET ABC transporter substrate-binding protein
KCBBIPOP_00629 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
KCBBIPOP_00630 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KCBBIPOP_00631 1.9e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCBBIPOP_00632 8e-99 metI P ABC transporter (Permease
KCBBIPOP_00633 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KCBBIPOP_00634 6.1e-120 ktrA P COG0569 K transport systems, NAD-binding component
KCBBIPOP_00635 1.9e-237 P COG0168 Trk-type K transport systems, membrane components
KCBBIPOP_00636 2.6e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
KCBBIPOP_00637 1.8e-90 yceD K metal-binding, possibly nucleic acid-binding protein
KCBBIPOP_00638 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCBBIPOP_00639 3.7e-282 T PhoQ Sensor
KCBBIPOP_00640 1.4e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCBBIPOP_00641 6.1e-216 dnaB L Replication initiation and membrane attachment
KCBBIPOP_00642 4.4e-166 dnaI L Primosomal protein DnaI
KCBBIPOP_00643 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KCBBIPOP_00644 2.3e-108
KCBBIPOP_00645 5.6e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KCBBIPOP_00646 2.5e-62 manO S protein conserved in bacteria
KCBBIPOP_00647 4e-167 manN G PTS system mannose fructose sorbose family IID component
KCBBIPOP_00648 1.2e-114 manM G pts system
KCBBIPOP_00649 3e-176 manL 2.7.1.191 G pts system
KCBBIPOP_00650 1e-66 manO S Protein conserved in bacteria
KCBBIPOP_00651 9.1e-159 manN G PTS system mannose fructose sorbose family IID component
KCBBIPOP_00652 4.1e-131 manY G pts system
KCBBIPOP_00653 6.9e-168 manL 2.7.1.191 G pts system
KCBBIPOP_00654 3.5e-137 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
KCBBIPOP_00655 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KCBBIPOP_00656 1.6e-247 pbuO S permease
KCBBIPOP_00657 8.5e-78 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
KCBBIPOP_00658 2.4e-92 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
KCBBIPOP_00659 1.1e-212 brpA K Transcriptional
KCBBIPOP_00660 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
KCBBIPOP_00661 2.4e-196 nusA K Participates in both transcription termination and antitermination
KCBBIPOP_00662 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
KCBBIPOP_00663 8e-42 ylxQ J ribosomal protein
KCBBIPOP_00664 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KCBBIPOP_00665 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KCBBIPOP_00666 1.3e-99 yvdD 3.2.2.10 S Belongs to the LOG family
KCBBIPOP_00667 3.1e-270 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KCBBIPOP_00668 1.2e-278 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
KCBBIPOP_00669 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
KCBBIPOP_00670 1.1e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
KCBBIPOP_00671 1.3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KCBBIPOP_00672 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
KCBBIPOP_00673 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
KCBBIPOP_00674 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KCBBIPOP_00675 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KCBBIPOP_00676 3e-72 ylbF S Belongs to the UPF0342 family
KCBBIPOP_00677 1.9e-46 ylbG S UPF0298 protein
KCBBIPOP_00678 2.8e-213 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KCBBIPOP_00679 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
KCBBIPOP_00680 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
KCBBIPOP_00681 3.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KCBBIPOP_00682 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KCBBIPOP_00683 5.4e-113 acuB S CBS domain
KCBBIPOP_00684 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KCBBIPOP_00685 3.1e-110 yvyE 3.4.13.9 S YigZ family
KCBBIPOP_00686 1.9e-250 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KCBBIPOP_00687 5.3e-84 comFC K competence protein
KCBBIPOP_00688 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KCBBIPOP_00689 4.8e-16 S Protein of unknown function (DUF2969)
KCBBIPOP_00692 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
KCBBIPOP_00695 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
KCBBIPOP_00696 2.2e-117 M Pfam SNARE associated Golgi protein
KCBBIPOP_00697 4.6e-177 S oxidoreductase
KCBBIPOP_00698 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
KCBBIPOP_00699 7.9e-87 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KCBBIPOP_00700 0.0 clpE O Belongs to the ClpA ClpB family
KCBBIPOP_00701 3.7e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KCBBIPOP_00702 1e-34 ykuJ S protein conserved in bacteria
KCBBIPOP_00703 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
KCBBIPOP_00704 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCBBIPOP_00705 9.1e-78 feoA P FeoA domain protein
KCBBIPOP_00706 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KCBBIPOP_00707 6.6e-08
KCBBIPOP_00708 1.3e-150 I Alpha/beta hydrolase family
KCBBIPOP_00709 6.9e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCBBIPOP_00710 8.3e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KCBBIPOP_00711 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
KCBBIPOP_00712 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KCBBIPOP_00713 2e-144 licT K antiterminator
KCBBIPOP_00714 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KCBBIPOP_00715 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KCBBIPOP_00716 5.8e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KCBBIPOP_00717 3.7e-151 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KCBBIPOP_00718 2.1e-100 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KCBBIPOP_00719 2.2e-221 mdtG EGP Major facilitator Superfamily
KCBBIPOP_00720 2e-33 secG U Preprotein translocase subunit SecG
KCBBIPOP_00721 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KCBBIPOP_00722 2.5e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KCBBIPOP_00723 2.1e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCBBIPOP_00724 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
KCBBIPOP_00725 6e-210 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KCBBIPOP_00726 1.9e-181 ccpA K Catabolite control protein A
KCBBIPOP_00727 2.3e-188 yyaQ S YjbR
KCBBIPOP_00728 1.6e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KCBBIPOP_00729 2.3e-78 yueI S Protein of unknown function (DUF1694)
KCBBIPOP_00730 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KCBBIPOP_00731 1.2e-25 WQ51_00785
KCBBIPOP_00732 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KCBBIPOP_00733 3.1e-220 ywbD 2.1.1.191 J Methyltransferase
KCBBIPOP_00734 7.3e-121 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KCBBIPOP_00735 3.1e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KCBBIPOP_00736 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KCBBIPOP_00737 5.8e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KCBBIPOP_00738 8.6e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KCBBIPOP_00739 4.2e-53 yheA S Belongs to the UPF0342 family
KCBBIPOP_00740 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KCBBIPOP_00741 1.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KCBBIPOP_00742 2.9e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KCBBIPOP_00743 3e-153 pheA 4.2.1.51 E Prephenate dehydratase
KCBBIPOP_00744 2.3e-249 msrR K Transcriptional regulator
KCBBIPOP_00745 1.6e-155 ydiA P C4-dicarboxylate transporter malic acid transport
KCBBIPOP_00746 2.7e-202 I acyl-CoA dehydrogenase
KCBBIPOP_00747 2e-97 mip S hydroperoxide reductase activity
KCBBIPOP_00748 3.2e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCBBIPOP_00749 1.9e-46 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCBBIPOP_00750 2.5e-91 Q Nodulation protein S (NodS)
KCBBIPOP_00751 3.5e-121 U COG COG3505 Type IV secretory pathway, VirD4 components
KCBBIPOP_00752 1e-69 L Integrase core domain
KCBBIPOP_00753 4.5e-18 K Psort location Cytoplasmic, score 8.87
KCBBIPOP_00754 9.7e-66 yvbK 3.1.3.25 K Acetyltransferase (GNAT) domain
KCBBIPOP_00755 1.2e-95
KCBBIPOP_00757 2.4e-102 K Transcriptional regulator
KCBBIPOP_00758 2.1e-126 ecsA V AAA domain, putative AbiEii toxin, Type IV TA system
KCBBIPOP_00759 1.5e-254 6.1.1.6 S Psort location CytoplasmicMembrane, score
KCBBIPOP_00760 2.8e-29 S Protein of unknown function (DUF1648)
KCBBIPOP_00761 1.4e-43 K Transcriptional regulator
KCBBIPOP_00762 1.1e-12
KCBBIPOP_00763 9.8e-138 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KCBBIPOP_00764 1e-199 yeaN P transporter
KCBBIPOP_00765 8.9e-153 yitS S EDD domain protein, DegV family
KCBBIPOP_00766 2e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
KCBBIPOP_00767 1.2e-112 cutC P Participates in the control of copper homeostasis
KCBBIPOP_00768 0.0 M family 8
KCBBIPOP_00769 2.6e-206 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
KCBBIPOP_00770 3.3e-144 yidA S hydrolases of the HAD superfamily
KCBBIPOP_00771 1.7e-159 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
KCBBIPOP_00772 8.4e-142 XK27_00120 2.4.2.3 F Phosphorylase superfamily
KCBBIPOP_00773 5.3e-68 ywiB S Domain of unknown function (DUF1934)
KCBBIPOP_00774 0.0 pacL 3.6.3.8 P cation transport ATPase
KCBBIPOP_00775 7.7e-132 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KCBBIPOP_00776 6.4e-159 yjjH S Calcineurin-like phosphoesterase
KCBBIPOP_00777 7.1e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCBBIPOP_00778 1.3e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KCBBIPOP_00779 3.2e-124 ftsE D cell division ATP-binding protein FtsE
KCBBIPOP_00780 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KCBBIPOP_00781 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
KCBBIPOP_00782 4.3e-177 yubA S permease
KCBBIPOP_00783 1.1e-223 G COG0457 FOG TPR repeat
KCBBIPOP_00784 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KCBBIPOP_00785 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KCBBIPOP_00786 1.9e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KCBBIPOP_00787 3.9e-87 ebsA S Family of unknown function (DUF5322)
KCBBIPOP_00788 2.4e-17 M LysM domain
KCBBIPOP_00789 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KCBBIPOP_00790 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCBBIPOP_00791 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KCBBIPOP_00792 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KCBBIPOP_00793 2e-85 XK27_03610 K Gnat family
KCBBIPOP_00794 5.5e-92 yybC
KCBBIPOP_00795 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KCBBIPOP_00796 7.9e-271 pepV 3.5.1.18 E Dipeptidase
KCBBIPOP_00797 9.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
KCBBIPOP_00798 4e-241 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
KCBBIPOP_00799 3.6e-134 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
KCBBIPOP_00800 1.6e-115 cps4C M biosynthesis protein
KCBBIPOP_00801 6.1e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
KCBBIPOP_00802 1.3e-257 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KCBBIPOP_00803 4.8e-126 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KCBBIPOP_00804 7.4e-160 licD M LICD family
KCBBIPOP_00805 6e-143 S Macro domain protein
KCBBIPOP_00806 6.3e-51 trxA O Belongs to the thioredoxin family
KCBBIPOP_00807 2.5e-74 yccU S CoA-binding protein
KCBBIPOP_00808 6.6e-145 tatD L Hydrolase, tatd
KCBBIPOP_00809 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KCBBIPOP_00810 3.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KCBBIPOP_00812 4e-164 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KCBBIPOP_00813 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KCBBIPOP_00814 1.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
KCBBIPOP_00815 1.4e-170 rmuC S RmuC domain protein
KCBBIPOP_00816 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
KCBBIPOP_00817 4e-142 purR 2.4.2.7 F operon repressor
KCBBIPOP_00818 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KCBBIPOP_00819 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KCBBIPOP_00820 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KCBBIPOP_00821 6.2e-185 gap 1.2.1.12 C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KCBBIPOP_00822 1.8e-122
KCBBIPOP_00823 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KCBBIPOP_00824 3e-87 S Fusaric acid resistance protein-like
KCBBIPOP_00825 2.5e-62 glnR K Transcriptional regulator
KCBBIPOP_00826 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
KCBBIPOP_00827 6.6e-116 pscB M CHAP domain protein
KCBBIPOP_00828 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCBBIPOP_00829 1.5e-33 ykzG S Belongs to the UPF0356 family
KCBBIPOP_00830 1.6e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
KCBBIPOP_00831 2e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KCBBIPOP_00832 1.5e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KCBBIPOP_00833 1.1e-113 azlC E AzlC protein
KCBBIPOP_00834 5.7e-47 azlD S branched-chain amino acid
KCBBIPOP_00835 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KCBBIPOP_00836 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KCBBIPOP_00837 2.5e-153 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCBBIPOP_00838 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KCBBIPOP_00839 6.1e-94 cvpA S toxin biosynthetic process
KCBBIPOP_00841 6.1e-146 V 'abc transporter, ATP-binding protein
KCBBIPOP_00842 9.5e-33 blpT
KCBBIPOP_00846 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KCBBIPOP_00847 8.4e-168 corA P COG0598 Mg2 and Co2 transporters
KCBBIPOP_00848 2.6e-123 XK27_01040 S Protein of unknown function (DUF1129)
KCBBIPOP_00850 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KCBBIPOP_00851 4.3e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KCBBIPOP_00852 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KCBBIPOP_00853 1.1e-42 XK27_05745
KCBBIPOP_00854 9e-223 mutY L A G-specific adenine glycosylase
KCBBIPOP_00855 2.9e-34
KCBBIPOP_00857 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCBBIPOP_00858 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KCBBIPOP_00859 3.8e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
KCBBIPOP_00860 4.3e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KCBBIPOP_00861 0.0 yjcE P NhaP-type Na H and K H antiporters
KCBBIPOP_00863 3.5e-97 ytqB J (SAM)-dependent
KCBBIPOP_00864 5.4e-183 yhcC S radical SAM protein
KCBBIPOP_00865 9.3e-187 ylbL T Belongs to the peptidase S16 family
KCBBIPOP_00866 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KCBBIPOP_00867 1.3e-91 rsmD 2.1.1.171 L Methyltransferase
KCBBIPOP_00868 3e-170 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KCBBIPOP_00869 5e-10 S Protein of unknown function (DUF4059)
KCBBIPOP_00870 4.2e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
KCBBIPOP_00871 8e-163 yxeN P ABC transporter (Permease
KCBBIPOP_00872 3.7e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KCBBIPOP_00873 3.6e-35
KCBBIPOP_00874 3.6e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCBBIPOP_00875 0.0 pflB 2.3.1.54 C formate acetyltransferase'
KCBBIPOP_00877 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
KCBBIPOP_00878 4.4e-146 cah 4.2.1.1 P carbonic anhydrase
KCBBIPOP_00879 9.4e-80 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KCBBIPOP_00880 3e-14 coiA 3.6.4.12 S Competence protein
KCBBIPOP_00881 3.4e-16 T peptidase
KCBBIPOP_00882 8.2e-149 rarD S Transporter
KCBBIPOP_00883 6.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KCBBIPOP_00884 3.4e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KCBBIPOP_00885 7.9e-136 yxkH G deacetylase
KCBBIPOP_00886 2.7e-205 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KCBBIPOP_00887 5.6e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KCBBIPOP_00888 1.3e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KCBBIPOP_00889 5.9e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KCBBIPOP_00890 2.9e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KCBBIPOP_00891 1.3e-142 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KCBBIPOP_00892 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
KCBBIPOP_00894 2e-231 2.7.13.3 T GHKL domain
KCBBIPOP_00895 5.6e-135 agrA KT response regulator
KCBBIPOP_00896 3.1e-07
KCBBIPOP_00897 4.3e-138 agrA KT response regulator
KCBBIPOP_00898 2.3e-81 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCBBIPOP_00899 1.1e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KCBBIPOP_00901 5e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KCBBIPOP_00902 4.5e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KCBBIPOP_00903 1.2e-238 purD 6.3.4.13 F Belongs to the GARS family
KCBBIPOP_00904 6.6e-156 S CHAP domain
KCBBIPOP_00905 4e-292 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KCBBIPOP_00906 2.2e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCBBIPOP_00907 6.1e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KCBBIPOP_00908 2.4e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KCBBIPOP_00909 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCBBIPOP_00910 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KCBBIPOP_00911 6.2e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCBBIPOP_00912 1.9e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KCBBIPOP_00913 3.1e-144 recO L Involved in DNA repair and RecF pathway recombination
KCBBIPOP_00914 3.8e-218 araT 2.6.1.1 E Aminotransferase
KCBBIPOP_00915 9.6e-163 S reductase
KCBBIPOP_00916 4.7e-168 K transcriptional regulator (lysR family)
KCBBIPOP_00917 2.7e-105 S CAAX amino terminal protease family protein
KCBBIPOP_00918 1.7e-308 S Glucan-binding protein C
KCBBIPOP_00919 1.5e-160 S CHAP domain
KCBBIPOP_00920 1.6e-22 L overlaps another CDS with the same product name
KCBBIPOP_00921 4.7e-50 insK L Integrase core domain protein
KCBBIPOP_00922 5.2e-33 L transposition
KCBBIPOP_00923 2.3e-181 coiA 3.6.4.12 S Competence protein
KCBBIPOP_00924 0.0 pepF E oligoendopeptidase F
KCBBIPOP_00925 4.5e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
KCBBIPOP_00926 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
KCBBIPOP_00927 7.8e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
KCBBIPOP_00928 1.7e-84 yxjI S LURP-one-related
KCBBIPOP_00929 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KCBBIPOP_00930 7.7e-143 M Polysaccharide biosynthesis protein
KCBBIPOP_00931 5.5e-243 S Polysaccharide biosynthesis protein
KCBBIPOP_00932 9.2e-26 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KCBBIPOP_00933 6.3e-89 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KCBBIPOP_00934 4.8e-108 pgm G Belongs to the phosphoglycerate mutase family
KCBBIPOP_00935 1.4e-107 G Belongs to the phosphoglycerate mutase family
KCBBIPOP_00936 1.7e-105 G Belongs to the phosphoglycerate mutase family
KCBBIPOP_00937 6.8e-196 S hmm pf01594
KCBBIPOP_00938 4.4e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCBBIPOP_00939 4.1e-38 S granule-associated protein
KCBBIPOP_00940 2e-278 S unusual protein kinase
KCBBIPOP_00941 8.4e-100 estA E Lysophospholipase L1 and related esterases
KCBBIPOP_00942 6.9e-153 rssA S Phospholipase, patatin family
KCBBIPOP_00943 5.3e-248 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
KCBBIPOP_00944 2.1e-211 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCBBIPOP_00945 1.7e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCBBIPOP_00946 8.2e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KCBBIPOP_00947 0.0 S the current gene model (or a revised gene model) may contain a frame shift
KCBBIPOP_00948 7.1e-109 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KCBBIPOP_00949 5.9e-108 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KCBBIPOP_00950 5.7e-172 S Helix-hairpin-helix DNA-binding motif class 1
KCBBIPOP_00951 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KCBBIPOP_00952 7.2e-164
KCBBIPOP_00953 1.4e-218 dcm 2.1.1.37 H cytosine-specific methyltransferase
KCBBIPOP_00954 1.2e-304
KCBBIPOP_00955 3.5e-56 lrgA S Effector of murein hydrolase LrgA
KCBBIPOP_00956 3.2e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KCBBIPOP_00957 1.7e-99 3.1.3.18 S IA, variant 1
KCBBIPOP_00958 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCBBIPOP_00959 6e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KCBBIPOP_00960 2.2e-114 serB 3.1.3.3 E phosphoserine phosphatase
KCBBIPOP_00961 5.5e-07 N PFAM Uncharacterised protein family UPF0150
KCBBIPOP_00962 1.1e-153 EG Permeases of the drug metabolite transporter (DMT) superfamily
KCBBIPOP_00964 6.4e-63 ycaO O OsmC-like protein
KCBBIPOP_00965 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
KCBBIPOP_00966 5.7e-10 O ADP-ribosylglycohydrolase
KCBBIPOP_00967 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCBBIPOP_00969 5.7e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KCBBIPOP_00970 1.7e-17 XK27_00735
KCBBIPOP_00971 3.9e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCBBIPOP_00972 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
KCBBIPOP_00973 3.6e-163 S CAAX amino terminal protease family protein
KCBBIPOP_00975 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KCBBIPOP_00976 3.4e-83 MA20_25245 K Gnat family
KCBBIPOP_00977 5.5e-115 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
KCBBIPOP_00978 8.3e-84 mutT 3.6.1.55 F Nudix family
KCBBIPOP_00979 1.6e-130 ET Belongs to the bacterial solute-binding protein 3 family
KCBBIPOP_00980 4.8e-132 ET Belongs to the bacterial solute-binding protein 3 family
KCBBIPOP_00981 4e-201 arcT 2.6.1.1 E Aminotransferase
KCBBIPOP_00982 3.8e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
KCBBIPOP_00983 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KCBBIPOP_00984 8.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KCBBIPOP_00985 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KCBBIPOP_00986 2.6e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KCBBIPOP_00987 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
KCBBIPOP_00988 1.5e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KCBBIPOP_00989 9.4e-218 S Predicted membrane protein (DUF2142)
KCBBIPOP_00990 4.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KCBBIPOP_00991 7.2e-90 S Psort location CytoplasmicMembrane, score
KCBBIPOP_00992 9.3e-226 amrA S membrane protein involved in the export of O-antigen and teichoic acid
KCBBIPOP_00993 6.3e-182 M Glycosyltransferase group 2 family protein
KCBBIPOP_00994 3.5e-126 arnC M group 2 family protein
KCBBIPOP_00995 3.8e-44 S Uncharacterized conserved protein (DUF2304)
KCBBIPOP_00996 7.7e-151 2.4.1.60 S Glycosyltransferase group 2 family protein
KCBBIPOP_00997 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
KCBBIPOP_00998 1.2e-222 M Psort location CytoplasmicMembrane, score
KCBBIPOP_00999 2.3e-221 GT4 M transferase activity, transferring glycosyl groups
KCBBIPOP_01000 3.5e-224 rgpA GT4 M Domain of unknown function (DUF1972)
KCBBIPOP_01001 1.9e-172 rgpB GT2 M Glycosyltransferase, group 2 family protein
KCBBIPOP_01002 4.4e-141 rgpC GM Transport permease protein
KCBBIPOP_01003 8.1e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KCBBIPOP_01004 4e-306 rgpF M Rhamnan synthesis protein F
KCBBIPOP_01005 1.5e-118 radC E Belongs to the UPF0758 family
KCBBIPOP_01006 8.2e-128 puuD T peptidase C26
KCBBIPOP_01007 2.1e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KCBBIPOP_01008 8.2e-60 XK27_04120 S Putative amino acid metabolism
KCBBIPOP_01009 7.5e-208 iscS 2.8.1.7 E Cysteine desulfurase
KCBBIPOP_01010 3.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCBBIPOP_01011 2.4e-101 yjbK S Adenylate cyclase
KCBBIPOP_01012 6.1e-120 yjbM 2.7.6.5 S Gtp pyrophosphokinase
KCBBIPOP_01013 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KCBBIPOP_01014 1e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KCBBIPOP_01015 2.1e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KCBBIPOP_01016 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KCBBIPOP_01017 4.9e-279 amiC P ABC transporter (Permease
KCBBIPOP_01018 1.4e-167 amiD P ABC transporter (Permease
KCBBIPOP_01019 3.9e-201 oppD P Belongs to the ABC transporter superfamily
KCBBIPOP_01020 1.2e-171 oppF P Belongs to the ABC transporter superfamily
KCBBIPOP_01021 8.1e-124 V Psort location CytoplasmicMembrane, score
KCBBIPOP_01022 4e-122 skfE V abc transporter atp-binding protein
KCBBIPOP_01023 5.6e-62 yvoA_1 K Transcriptional
KCBBIPOP_01024 1.4e-147 supH S overlaps another CDS with the same product name
KCBBIPOP_01025 3.5e-146 XK27_02985 S overlaps another CDS with the same product name
KCBBIPOP_01026 1e-193 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KCBBIPOP_01027 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KCBBIPOP_01028 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
KCBBIPOP_01029 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCBBIPOP_01030 8.1e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCBBIPOP_01031 1.6e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCBBIPOP_01032 4.8e-137 stp 3.1.3.16 T phosphatase
KCBBIPOP_01033 8.9e-302 prkC 2.7.11.1 KLT serine threonine protein kinase
KCBBIPOP_01034 3.8e-94 kcsA P Ion transport protein
KCBBIPOP_01035 8.6e-117 yvqF S Membrane
KCBBIPOP_01036 1.9e-170 vraS 2.7.13.3 T Histidine kinase
KCBBIPOP_01037 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KCBBIPOP_01040 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCBBIPOP_01041 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KCBBIPOP_01042 3.5e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KCBBIPOP_01043 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KCBBIPOP_01044 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCBBIPOP_01045 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KCBBIPOP_01046 3.1e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KCBBIPOP_01047 2.8e-181 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
KCBBIPOP_01048 1.3e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KCBBIPOP_01049 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KCBBIPOP_01050 6.5e-99 2.3.1.128 K Acetyltransferase GNAT Family
KCBBIPOP_01051 4.7e-285 S Protein of unknown function (DUF3114)
KCBBIPOP_01053 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
KCBBIPOP_01054 5.7e-295 V abc transporter atp-binding protein
KCBBIPOP_01055 0.0 V abc transporter atp-binding protein
KCBBIPOP_01056 6.9e-188 XK27_10075 S abc transporter atp-binding protein
KCBBIPOP_01058 0.0 glgE 2.3.1.12, 2.4.99.16, 3.2.1.1, 3.2.1.14 GH13,GH18 M Pilin isopeptide linkage domain protein
KCBBIPOP_01060 0.0 M Pilin isopeptide linkage domain protein
KCBBIPOP_01061 0.0 zmpB M signal peptide protein, YSIRK family
KCBBIPOP_01062 0.0 GM domain, Protein
KCBBIPOP_01063 7.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KCBBIPOP_01064 0.0 sbcC L ATPase involved in DNA repair
KCBBIPOP_01065 3.4e-155 cat 2.3.1.28 S acetyltransferase'
KCBBIPOP_01066 0.0 M family 8
KCBBIPOP_01067 2e-147 epsH S acetyltransferase'
KCBBIPOP_01068 2e-238 M Glycosyltransferase, family 8
KCBBIPOP_01069 3.1e-289 tagE 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KCBBIPOP_01070 4.3e-196 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KCBBIPOP_01071 1.6e-185 nss M transferase activity, transferring glycosyl groups
KCBBIPOP_01072 4.8e-243 M Glycosyltransferase, family 8
KCBBIPOP_01073 1.3e-167 cpsJ M Glycosyltransferase group 2 family protein
KCBBIPOP_01074 0.0 M cog cog1442
KCBBIPOP_01075 1.1e-242 M family 8
KCBBIPOP_01076 2.3e-165 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
KCBBIPOP_01077 6.9e-308 asp1 S Accessory Sec system protein Asp1
KCBBIPOP_01078 2.1e-301 asp2 3.4.11.5 S Accessory Sec system protein Asp2
KCBBIPOP_01079 1.6e-68 asp3 S Accessory Sec system protein Asp3
KCBBIPOP_01080 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KCBBIPOP_01081 1.1e-12 S Accessory secretory protein Sec Asp4
KCBBIPOP_01082 7e-12 S Accessory secretory protein Sec, Asp5
KCBBIPOP_01083 1.3e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCBBIPOP_01084 6.6e-237 dltB M Membrane protein involved in D-alanine export
KCBBIPOP_01085 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCBBIPOP_01086 3e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KCBBIPOP_01087 0.0 3.6.3.8 P cation transport ATPase
KCBBIPOP_01088 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
KCBBIPOP_01090 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KCBBIPOP_01091 1.6e-165 metF 1.5.1.20 E reductase
KCBBIPOP_01092 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KCBBIPOP_01093 6.3e-70 argR K Regulates arginine biosynthesis genes
KCBBIPOP_01094 7.9e-58 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KCBBIPOP_01095 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KCBBIPOP_01096 4.2e-80 S Protein of unknown function (DUF3021)
KCBBIPOP_01097 1.8e-72 K LytTr DNA-binding domain
KCBBIPOP_01099 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KCBBIPOP_01101 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KCBBIPOP_01102 3.4e-100 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
KCBBIPOP_01103 1.6e-230 cinA 3.5.1.42 S Belongs to the CinA family
KCBBIPOP_01104 6.1e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCBBIPOP_01105 1.9e-153 endA F DNA RNA non-specific endonuclease
KCBBIPOP_01106 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
KCBBIPOP_01107 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCBBIPOP_01109 2e-208 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
KCBBIPOP_01110 5.5e-250 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
KCBBIPOP_01112 8.4e-137
KCBBIPOP_01113 1.1e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KCBBIPOP_01114 1.9e-149 L PFAM Integrase, catalytic core
KCBBIPOP_01115 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KCBBIPOP_01116 1.3e-268 argH 4.3.2.1 E Argininosuccinate lyase
KCBBIPOP_01117 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KCBBIPOP_01118 1.3e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KCBBIPOP_01119 1.5e-181 jag S RNA-binding protein
KCBBIPOP_01120 6.9e-107 K Transcriptional regulator
KCBBIPOP_01121 1.5e-103 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
KCBBIPOP_01122 3.4e-14 rpmH J Ribosomal protein L34
KCBBIPOP_01123 2.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KCBBIPOP_01126 3.8e-96 S reductase
KCBBIPOP_01127 3.9e-72 badR K Transcriptional regulator, marr family
KCBBIPOP_01128 5.5e-36 XK27_02060 S Transglycosylase associated protein
KCBBIPOP_01129 3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KCBBIPOP_01130 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCBBIPOP_01135 1.9e-07
KCBBIPOP_01137 1.9e-169 G Belongs to the carbohydrate kinase PfkB family
KCBBIPOP_01138 9.4e-253 F Belongs to the purine-cytosine permease (2.A.39) family
KCBBIPOP_01139 5.6e-194 yegU O ADP-ribosylglycohydrolase
KCBBIPOP_01140 9.1e-39 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
KCBBIPOP_01141 1.1e-149 cbiO2 P 'abc transporter, ATP-binding protein
KCBBIPOP_01142 1.1e-158 P abc transporter atp-binding protein
KCBBIPOP_01143 9.7e-133 cbiQ P cobalt transport
KCBBIPOP_01144 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
KCBBIPOP_01145 2.3e-24 L Transposase
KCBBIPOP_01146 2.9e-111 tcyB_2 P ABC transporter (permease)
KCBBIPOP_01147 1.9e-116 gltJ P ABC transporter (Permease
KCBBIPOP_01148 2.2e-143 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KCBBIPOP_01149 3.3e-138 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCBBIPOP_01150 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCBBIPOP_01151 9.2e-220 vicK 2.7.13.3 T Histidine kinase
KCBBIPOP_01152 4.6e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KCBBIPOP_01153 8.7e-57 S Protein of unknown function (DUF454)
KCBBIPOP_01155 1.6e-179 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
KCBBIPOP_01156 3.2e-141 cppA E CppA N-terminal
KCBBIPOP_01157 7e-108 V CAAX protease self-immunity
KCBBIPOP_01158 1.2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KCBBIPOP_01159 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KCBBIPOP_01160 7.9e-34 L COG1943 Transposase and inactivated derivatives
KCBBIPOP_01162 1.7e-27 M Plasmid recombination enzyme
KCBBIPOP_01164 7.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KCBBIPOP_01165 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KCBBIPOP_01166 1.4e-202 V permease protein
KCBBIPOP_01167 9.9e-121 macB V ABC transporter, ATP-binding protein
KCBBIPOP_01168 9.4e-183 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCBBIPOP_01169 4.7e-129 2.1.1.223 S Putative SAM-dependent methyltransferase
KCBBIPOP_01170 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
KCBBIPOP_01171 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
KCBBIPOP_01172 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KCBBIPOP_01173 1.6e-222 pyrP F uracil Permease
KCBBIPOP_01174 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KCBBIPOP_01175 2.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KCBBIPOP_01176 9.8e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KCBBIPOP_01177 1.5e-166 fhuR K transcriptional regulator (lysR family)
KCBBIPOP_01179 5.1e-73 K Helix-turn-helix
KCBBIPOP_01181 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCBBIPOP_01182 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KCBBIPOP_01183 6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
KCBBIPOP_01184 1.2e-255 cycA E permease
KCBBIPOP_01185 2e-39 ynzC S UPF0291 protein
KCBBIPOP_01186 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KCBBIPOP_01187 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KCBBIPOP_01188 1.1e-218 S membrane
KCBBIPOP_01189 9.8e-211 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCBBIPOP_01190 1.9e-292 nptA P COG1283 Na phosphate symporter
KCBBIPOP_01191 3.6e-114 3.4.17.14, 3.5.1.28 NU amidase activity
KCBBIPOP_01192 1.2e-81 S Bacterial inner membrane protein
KCBBIPOP_01193 6.6e-145 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
KCBBIPOP_01194 1.7e-108 S HD domain
KCBBIPOP_01195 1.6e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
KCBBIPOP_01196 1.9e-53 glnB K Belongs to the P(II) protein family
KCBBIPOP_01197 1.9e-228 amt P Ammonium Transporter
KCBBIPOP_01198 4e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KCBBIPOP_01199 8.1e-54 yabA L Involved in initiation control of chromosome replication
KCBBIPOP_01200 2.6e-133 yaaT S stage 0 sporulation protein
KCBBIPOP_01201 9.6e-158 holB 2.7.7.7 L dna polymerase iii
KCBBIPOP_01202 2.4e-110 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCBBIPOP_01204 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KCBBIPOP_01205 2.6e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KCBBIPOP_01206 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCBBIPOP_01207 5.1e-216 ftsW D Belongs to the SEDS family
KCBBIPOP_01208 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KCBBIPOP_01209 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KCBBIPOP_01210 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KCBBIPOP_01211 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KCBBIPOP_01212 4.6e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCBBIPOP_01213 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KCBBIPOP_01214 2.8e-123 atpB C it plays a direct role in the translocation of protons across the membrane
KCBBIPOP_01215 5.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCBBIPOP_01216 1.6e-187 femA 2.3.2.10, 2.3.2.16 V FemAB family
KCBBIPOP_01218 4.9e-60 arsC 1.20.4.1 P Belongs to the ArsC family
KCBBIPOP_01219 5.4e-73 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
KCBBIPOP_01220 7.4e-222 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCBBIPOP_01221 5.1e-104 wecD M Acetyltransferase (GNAT) domain
KCBBIPOP_01222 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KCBBIPOP_01223 8.3e-157 GK ROK family
KCBBIPOP_01224 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
KCBBIPOP_01225 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
KCBBIPOP_01226 1.8e-203 potD P spermidine putrescine ABC transporter
KCBBIPOP_01227 4.4e-130 potC P ABC-type spermidine putrescine transport system, permease component II
KCBBIPOP_01228 1.5e-138 potB P ABC-type spermidine putrescine transport system, permease component I
KCBBIPOP_01229 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KCBBIPOP_01230 7.3e-169 murB 1.3.1.98 M cell wall formation
KCBBIPOP_01231 2.4e-81 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KCBBIPOP_01232 4.1e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KCBBIPOP_01233 9e-294 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KCBBIPOP_01234 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCBBIPOP_01235 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
KCBBIPOP_01236 0.0 ydaO E amino acid
KCBBIPOP_01237 4.1e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KCBBIPOP_01238 2.4e-37 ylqC L Belongs to the UPF0109 family
KCBBIPOP_01239 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KCBBIPOP_01241 7.8e-198 2.7.13.3 T GHKL domain
KCBBIPOP_01242 2.1e-129 agrA KT phosphorelay signal transduction system
KCBBIPOP_01243 1.8e-189 O protein import
KCBBIPOP_01244 5.1e-167 tehB 2.1.1.265 PQ tellurite resistance protein tehb
KCBBIPOP_01245 2.9e-17 yjdB S Domain of unknown function (DUF4767)
KCBBIPOP_01246 1.6e-196 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCBBIPOP_01248 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
KCBBIPOP_01249 5.8e-72 S QueT transporter
KCBBIPOP_01251 3.5e-172 yfjR K regulation of single-species biofilm formation
KCBBIPOP_01252 7.4e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KCBBIPOP_01253 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCBBIPOP_01254 1.7e-85 ccl S cog cog4708
KCBBIPOP_01255 2.8e-163 rbn E Belongs to the UPF0761 family
KCBBIPOP_01256 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KCBBIPOP_01257 3e-232 ytoI K transcriptional regulator containing CBS domains
KCBBIPOP_01258 2.8e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
KCBBIPOP_01259 2.6e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCBBIPOP_01260 0.0 comEC S Competence protein ComEC
KCBBIPOP_01261 1.2e-94 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KCBBIPOP_01262 4.9e-142 plsC 2.3.1.51 I Acyltransferase
KCBBIPOP_01263 1.2e-156 nodB3 G deacetylase
KCBBIPOP_01264 5.5e-141 yabB 2.1.1.223 L Methyltransferase
KCBBIPOP_01265 7e-43 yazA L endonuclease containing a URI domain
KCBBIPOP_01266 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KCBBIPOP_01267 7.4e-153 corA P CorA-like protein
KCBBIPOP_01268 2.5e-62 yjqA S Bacterial PH domain
KCBBIPOP_01269 7.8e-100 thiT S Thiamine transporter
KCBBIPOP_01270 2e-152 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KCBBIPOP_01271 2.1e-192 yjbB G Permeases of the major facilitator superfamily
KCBBIPOP_01272 4e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KCBBIPOP_01273 4e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
KCBBIPOP_01274 8.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KCBBIPOP_01275 3.3e-155 cjaA ET ABC transporter substrate-binding protein
KCBBIPOP_01276 1.5e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCBBIPOP_01277 1e-106 P ABC transporter (Permease
KCBBIPOP_01278 3e-114 papP P ABC transporter (Permease
KCBBIPOP_01279 5.4e-192 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KCBBIPOP_01280 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
KCBBIPOP_01281 0.0 copA 3.6.3.54 P P-type ATPase
KCBBIPOP_01282 1.2e-73 copY K negative regulation of transcription, DNA-templated
KCBBIPOP_01283 3e-175 EGP Major facilitator Superfamily
KCBBIPOP_01287 1.1e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KCBBIPOP_01288 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KCBBIPOP_01289 2.7e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
KCBBIPOP_01290 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KCBBIPOP_01291 1.1e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCBBIPOP_01292 2.7e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
KCBBIPOP_01293 1.2e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCBBIPOP_01294 1.5e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
KCBBIPOP_01295 1.2e-59
KCBBIPOP_01296 0.0 ctpE P E1-E2 ATPase
KCBBIPOP_01297 4.1e-44
KCBBIPOP_01298 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KCBBIPOP_01300 1.5e-124 V abc transporter atp-binding protein
KCBBIPOP_01301 0.0 V ABC transporter (Permease
KCBBIPOP_01302 1.2e-129 K transcriptional regulator, MerR family
KCBBIPOP_01303 6.4e-105 dnaQ 2.7.7.7 L DNA polymerase III
KCBBIPOP_01304 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
KCBBIPOP_01305 6.3e-63 XK27_02560 S cog cog2151
KCBBIPOP_01306 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KCBBIPOP_01307 4.7e-224 ytfP S Flavoprotein
KCBBIPOP_01309 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KCBBIPOP_01310 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
KCBBIPOP_01311 3.8e-177 ecsB U Bacterial ABC transporter protein EcsB
KCBBIPOP_01312 2e-132 ecsA V abc transporter atp-binding protein
KCBBIPOP_01313 5e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KCBBIPOP_01316 1.6e-103
KCBBIPOP_01318 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
KCBBIPOP_01319 7.9e-44 yoeB S Addiction module toxin, Txe YoeB family
KCBBIPOP_01320 7.6e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
KCBBIPOP_01321 2.2e-196 ylbM S Belongs to the UPF0348 family
KCBBIPOP_01322 1.3e-139 yqeM Q Methyltransferase domain protein
KCBBIPOP_01323 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KCBBIPOP_01324 1.8e-104 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KCBBIPOP_01325 2.9e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCBBIPOP_01326 7.7e-49 yhbY J RNA-binding protein
KCBBIPOP_01327 5.4e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KCBBIPOP_01328 1e-98 yqeG S hydrolase of the HAD superfamily
KCBBIPOP_01329 3.1e-151 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KCBBIPOP_01330 4.2e-65
KCBBIPOP_01332 1.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCBBIPOP_01333 2.2e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KCBBIPOP_01334 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCBBIPOP_01335 3.6e-63 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KCBBIPOP_01336 9.8e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCBBIPOP_01337 3.7e-99 pncA Q isochorismatase
KCBBIPOP_01338 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KCBBIPOP_01339 5.3e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
KCBBIPOP_01340 9e-75 XK27_03180 T universal stress protein
KCBBIPOP_01342 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCBBIPOP_01343 5.6e-10 MU outer membrane autotransporter barrel domain protein
KCBBIPOP_01347 5.4e-44 spiA K sequence-specific DNA binding
KCBBIPOP_01349 1.3e-134 agrA KT LytTr DNA-binding domain
KCBBIPOP_01350 2.7e-228 blpH 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KCBBIPOP_01354 1.3e-204 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KCBBIPOP_01355 5.4e-172 S glycosyl transferase family 2
KCBBIPOP_01356 4e-85
KCBBIPOP_01357 1.7e-204 M glycosyl transferase group 1
KCBBIPOP_01358 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCBBIPOP_01359 3.3e-91 usp 3.5.1.28 CBM50 S CHAP domain
KCBBIPOP_01360 1.9e-84 mreD M rod shape-determining protein MreD
KCBBIPOP_01361 1.2e-106 mreC M Involved in formation and maintenance of cell shape
KCBBIPOP_01367 2.6e-10
KCBBIPOP_01377 5.9e-33 3.4.24.40 U Large extracellular alpha-helical protein
KCBBIPOP_01378 1.5e-174 S hydrolase
KCBBIPOP_01379 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
KCBBIPOP_01380 1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KCBBIPOP_01381 3e-63 K sequence-specific DNA binding
KCBBIPOP_01382 0.0 cbpD 3.5.1.28 NU GBS Bsp-like repeat
KCBBIPOP_01383 4.3e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KCBBIPOP_01384 8.4e-66 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCBBIPOP_01385 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
KCBBIPOP_01386 3.4e-77 yfiQ K Acetyltransferase (GNAT) domain
KCBBIPOP_01387 4.6e-143 S ABC-2 family transporter protein
KCBBIPOP_01388 1.2e-141 S ABC-2 family transporter protein
KCBBIPOP_01389 6.1e-185 S AAA domain, putative AbiEii toxin, Type IV TA system
KCBBIPOP_01390 3.7e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KCBBIPOP_01391 2.5e-184 desK 2.7.13.3 T Histidine kinase
KCBBIPOP_01392 5.3e-133 yvfS V ABC-2 type transporter
KCBBIPOP_01393 1.5e-158 XK27_09825 V 'abc transporter, ATP-binding protein
KCBBIPOP_01396 5.1e-165 yocS S Transporter
KCBBIPOP_01397 1.5e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
KCBBIPOP_01398 1.2e-275 P ABC transporter transmembrane region
KCBBIPOP_01400 6.7e-75 XK27_01300 P Protein conserved in bacteria
KCBBIPOP_01401 8e-85 FNV0100 F Belongs to the Nudix hydrolase family
KCBBIPOP_01402 2.9e-48 3.6.1.55 F NUDIX domain
KCBBIPOP_01403 5.9e-10
KCBBIPOP_01404 1.3e-142
KCBBIPOP_01405 1.6e-25 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
KCBBIPOP_01406 2.2e-115 yvfS V Transporter
KCBBIPOP_01407 2.2e-157 XK27_09825 V abc transporter atp-binding protein
KCBBIPOP_01408 9.1e-15 liaI KT membrane
KCBBIPOP_01409 3.4e-30 liaI KT membrane
KCBBIPOP_01410 6.1e-93 XK27_05000 S metal cluster binding
KCBBIPOP_01411 0.0 V ABC transporter (permease)
KCBBIPOP_01412 3.2e-133 macB2 V ABC transporter, ATP-binding protein
KCBBIPOP_01413 7.4e-151 T Histidine kinase
KCBBIPOP_01414 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCBBIPOP_01415 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KCBBIPOP_01416 1.1e-223 pbuX F xanthine permease
KCBBIPOP_01417 4.4e-60 pdxH S pyridoxamine 5'-phosphate oxidase
KCBBIPOP_01418 8.7e-243 norM V Multidrug efflux pump
KCBBIPOP_01420 1.8e-181 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCBBIPOP_01421 1.2e-231 brnQ E Component of the transport system for branched-chain amino acids
KCBBIPOP_01422 1.6e-182 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCBBIPOP_01423 1.8e-59 S Protein of unknown function (DUF3290)
KCBBIPOP_01424 1.5e-107 S Protein of unknown function (DUF421)
KCBBIPOP_01425 7.4e-18 csbD K CsbD-like
KCBBIPOP_01426 1.5e-105 S Carbohydrate-binding domain-containing protein Cthe_2159
KCBBIPOP_01427 6.8e-51 XK27_01300 P Protein conserved in bacteria
KCBBIPOP_01428 2.1e-215 yfnA E amino acid
KCBBIPOP_01429 0.0 S dextransucrase activity
KCBBIPOP_01430 8.7e-139 tcyC2 3.6.3.21 E abc transporter atp-binding protein
KCBBIPOP_01431 4.3e-113 yxeN P ABC transporter, permease protein
KCBBIPOP_01432 9.1e-111 ytmL P ABC transporter (Permease
KCBBIPOP_01433 4e-164 ET ABC transporter substrate-binding protein
KCBBIPOP_01434 9.5e-178 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
KCBBIPOP_01435 2.3e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KCBBIPOP_01436 1.5e-42 S Sugar efflux transporter for intercellular exchange
KCBBIPOP_01437 4.1e-201 P FtsX-like permease family
KCBBIPOP_01438 6.6e-122 V abc transporter atp-binding protein
KCBBIPOP_01439 2.1e-97 K WHG domain
KCBBIPOP_01440 1.7e-168 ydhF S Aldo keto reductase
KCBBIPOP_01441 1.6e-211 natB CP ABC-type Na efflux pump, permease component
KCBBIPOP_01442 3.3e-161 natA S abc transporter atp-binding protein
KCBBIPOP_01443 1.7e-07 S Protein of unknown function (DUF3169)
KCBBIPOP_01444 9.4e-27 XK27_07105 K transcriptional
KCBBIPOP_01445 4.4e-35
KCBBIPOP_01446 4.3e-109 XK27_02070 S nitroreductase
KCBBIPOP_01447 3.8e-143 1.13.11.2 S glyoxalase
KCBBIPOP_01448 3.7e-73 ywnA K Transcriptional regulator
KCBBIPOP_01449 3.6e-157 E Alpha/beta hydrolase of unknown function (DUF915)
KCBBIPOP_01450 1.6e-230 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KCBBIPOP_01451 4.3e-107 drgA C Nitroreductase family
KCBBIPOP_01452 4.6e-99 yoaK S Protein of unknown function (DUF1275)
KCBBIPOP_01453 2.4e-158 yvgN C reductase
KCBBIPOP_01454 1e-210 S Tetratricopeptide repeat
KCBBIPOP_01455 0.0 lacL 3.2.1.23 G -beta-galactosidase
KCBBIPOP_01456 0.0 lacS G transporter
KCBBIPOP_01457 5.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KCBBIPOP_01458 8.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCBBIPOP_01459 4.1e-286 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KCBBIPOP_01460 1.8e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KCBBIPOP_01461 1.2e-151 galR K Transcriptional regulator
KCBBIPOP_01462 1.3e-306 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
KCBBIPOP_01463 6.7e-196 gtfA 2.4.1.329, 2.4.1.7 GH13 G Alpha amylase, catalytic domain
KCBBIPOP_01464 2.9e-96 iolC 2.7.1.4 G pfkB family carbohydrate kinase
KCBBIPOP_01465 8e-189 msmX P Belongs to the ABC transporter superfamily
KCBBIPOP_01466 2.4e-142 msmG P ABC-type sugar transport system, permease component
KCBBIPOP_01467 4.1e-145 msmF P Binding-protein-dependent transport system inner membrane component
KCBBIPOP_01468 7e-194 msmE G Bacterial extracellular solute-binding protein
KCBBIPOP_01469 0.0 rafA 3.2.1.22 G alpha-galactosidase
KCBBIPOP_01470 1.9e-147 msmR K AraC family transcriptional regulator
KCBBIPOP_01471 1.5e-289 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
KCBBIPOP_01472 1.2e-215 vncS 2.7.13.3 T Histidine kinase
KCBBIPOP_01473 2.2e-114 K Response regulator receiver domain protein
KCBBIPOP_01474 2.2e-233 vex3 V Efflux ABC transporter, permease protein
KCBBIPOP_01475 1e-108 vex2 V abc transporter atp-binding protein
KCBBIPOP_01476 6.4e-179 vex1 V Efflux ABC transporter, permease protein
KCBBIPOP_01477 6.2e-282 XK27_07020 S Belongs to the UPF0371 family
KCBBIPOP_01479 3.8e-196 gldA 1.1.1.6 C glycerol dehydrogenase
KCBBIPOP_01480 1.6e-177 XK27_10475 S oxidoreductase
KCBBIPOP_01481 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
KCBBIPOP_01482 1.7e-94 dhaL 2.7.1.121 S Dihydroxyacetone kinase
KCBBIPOP_01483 1.8e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
KCBBIPOP_01484 7.7e-225 thrE K Psort location CytoplasmicMembrane, score
KCBBIPOP_01485 0.0 M Putative cell wall binding repeat
KCBBIPOP_01486 4.1e-34 S Immunity protein 41
KCBBIPOP_01487 0.0 pepO 3.4.24.71 O Peptidase family M13
KCBBIPOP_01488 2.4e-08 S Enterocin A Immunity
KCBBIPOP_01489 7.8e-191 mccF V LD-carboxypeptidase
KCBBIPOP_01490 3.6e-15 S integral membrane protein
KCBBIPOP_01491 4.2e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
KCBBIPOP_01492 4.9e-110 yhfC S Putative membrane peptidase family (DUF2324)
KCBBIPOP_01493 4.4e-49 3.6.1.55 F NUDIX domain
KCBBIPOP_01495 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KCBBIPOP_01496 1.3e-232 L DNA binding domain of tn916 integrase
KCBBIPOP_01497 1.8e-30 xis S Excisionase from transposon Tn916
KCBBIPOP_01498 9.3e-36 S Helix-turn-helix domain
KCBBIPOP_01499 1.1e-71 phyR K Sigma-70, region 4
KCBBIPOP_01500 3.9e-37 K Helix-turn-helix domain
KCBBIPOP_01501 0.0 L Transposase and inactivated derivatives, TnpA family
KCBBIPOP_01502 5.6e-95 L Resolvase, N terminal domain
KCBBIPOP_01503 1.6e-16
KCBBIPOP_01504 1.6e-134 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
KCBBIPOP_01505 0.0 tetP J elongation factor G
KCBBIPOP_01507 4.8e-59 L thioesterase
KCBBIPOP_01508 2.6e-55 bta 1.8.1.8 CO cell redox homeostasis
KCBBIPOP_01510 3.2e-65 L Transposase (IS116 IS110 IS902 family)
KCBBIPOP_01511 4.9e-142 L PFAM transposase IS116 IS110 IS902 family
KCBBIPOP_01512 2.1e-12
KCBBIPOP_01515 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCBBIPOP_01516 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KCBBIPOP_01517 2.5e-231 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KCBBIPOP_01518 1.3e-238 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
KCBBIPOP_01520 3e-60 divIC D Septum formation initiator
KCBBIPOP_01521 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KCBBIPOP_01522 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCBBIPOP_01523 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KCBBIPOP_01524 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KCBBIPOP_01525 1.1e-29 yyzM S Protein conserved in bacteria
KCBBIPOP_01526 2.1e-197 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KCBBIPOP_01527 1.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KCBBIPOP_01528 2.6e-135 parB K Belongs to the ParB family
KCBBIPOP_01529 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KCBBIPOP_01530 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KCBBIPOP_01531 6.2e-120 yoaK S Protein of unknown function (DUF1275)
KCBBIPOP_01535 0.0 XK27_10405 S Bacterial membrane protein YfhO
KCBBIPOP_01536 5.1e-306 ybiT S abc transporter atp-binding protein
KCBBIPOP_01537 4.9e-154 yvjA S membrane
KCBBIPOP_01538 2.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KCBBIPOP_01539 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KCBBIPOP_01540 1e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCBBIPOP_01541 8.9e-60 yaaA S S4 domain protein YaaA
KCBBIPOP_01542 4.8e-235 ymfF S Peptidase M16
KCBBIPOP_01543 1.9e-239 ymfH S Peptidase M16
KCBBIPOP_01544 7.5e-131 S sequence-specific DNA binding
KCBBIPOP_01545 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCBBIPOP_01546 4.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCBBIPOP_01547 1.6e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCBBIPOP_01548 2.8e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCBBIPOP_01549 1.7e-70 lytE M LysM domain protein
KCBBIPOP_01550 5.8e-65 isaA GH23 M Immunodominant staphylococcal antigen A
KCBBIPOP_01551 0.0 S Bacterial membrane protein, YfhO
KCBBIPOP_01552 9.6e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KCBBIPOP_01553 2.4e-99 yvbG U UPF0056 membrane protein
KCBBIPOP_01554 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KCBBIPOP_01555 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KCBBIPOP_01556 2.2e-73 rplI J binds to the 23S rRNA
KCBBIPOP_01557 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KCBBIPOP_01558 1.8e-47 veg S Biofilm formation stimulator VEG
KCBBIPOP_01559 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KCBBIPOP_01560 6.1e-184 sip L Belongs to the 'phage' integrase family
KCBBIPOP_01561 3.2e-18 xre K Cro/C1-type HTH DNA-binding domain
KCBBIPOP_01562 1.8e-19 K Cro/C1-type HTH DNA-binding domain
KCBBIPOP_01566 2.2e-14
KCBBIPOP_01567 9e-22
KCBBIPOP_01568 9.8e-139 KL Phage plasmid primase P4 family
KCBBIPOP_01569 1.7e-242 S DNA primase
KCBBIPOP_01571 2.3e-14
KCBBIPOP_01574 2.5e-31
KCBBIPOP_01575 2.5e-19
KCBBIPOP_01576 1.9e-10
KCBBIPOP_01577 4.1e-54 ypaA M Membrane
KCBBIPOP_01578 9.9e-97 XK27_06935 K transcriptional regulator
KCBBIPOP_01579 5.6e-160 XK27_06930 V domain protein
KCBBIPOP_01580 3.6e-109 S Putative adhesin
KCBBIPOP_01581 7.8e-63 XK27_06920 S Protein of unknown function (DUF1700)
KCBBIPOP_01582 6.3e-54 K transcriptional regulator, PadR family
KCBBIPOP_01583 7.5e-117 nudL L hydrolase
KCBBIPOP_01587 0.0 S Protein of unknown function DUF262
KCBBIPOP_01588 1.3e-77 S EcsC protein family
KCBBIPOP_01590 3.9e-130
KCBBIPOP_01591 7e-262 mloB K Transcriptional regulator
KCBBIPOP_01592 2.6e-65
KCBBIPOP_01593 4.4e-13
KCBBIPOP_01594 6.4e-62
KCBBIPOP_01595 1.1e-197 L Replication initiation factor
KCBBIPOP_01597 1.3e-276 L DNA integration
KCBBIPOP_01598 1.8e-229
KCBBIPOP_01599 7.4e-127 P ATPases associated with a variety of cellular activities
KCBBIPOP_01600 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KCBBIPOP_01601 3.4e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KCBBIPOP_01602 3.6e-218 metE 2.1.1.14 E Methionine synthase
KCBBIPOP_01603 1.4e-07 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KCBBIPOP_01604 9.2e-48 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KCBBIPOP_01605 3.6e-53 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KCBBIPOP_01606 3.1e-237 hisS 6.1.1.21 J histidyl-tRNA synthetase
KCBBIPOP_01608 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KCBBIPOP_01609 3.2e-167 XK27_01785 S cog cog1284
KCBBIPOP_01610 5.7e-121 yaaA S Belongs to the UPF0246 family
KCBBIPOP_01611 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCBBIPOP_01612 1.6e-88 XK27_10930 K acetyltransferase
KCBBIPOP_01613 1.7e-13
KCBBIPOP_01614 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KCBBIPOP_01615 1.7e-288 ccs S the current gene model (or a revised gene model) may contain a frame shift
KCBBIPOP_01616 3.2e-44 yrzB S Belongs to the UPF0473 family
KCBBIPOP_01617 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCBBIPOP_01618 6.3e-44 yrzL S Belongs to the UPF0297 family
KCBBIPOP_01619 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KCBBIPOP_01620 1.7e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
KCBBIPOP_01622 7.2e-214 int L Belongs to the 'phage' integrase family
KCBBIPOP_01623 1.9e-18 S Domain of unknown function (DUF3173)
KCBBIPOP_01624 1.1e-157 L Replication initiation factor
KCBBIPOP_01625 8e-88 K sequence-specific DNA binding
KCBBIPOP_01626 2.5e-173 yeiH S membrane
KCBBIPOP_01627 4.7e-197 ltrA S Low temperature requirement protein
KCBBIPOP_01629 3.8e-90 adk 2.7.4.3 F topology modulation protein
KCBBIPOP_01630 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KCBBIPOP_01631 9.8e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCBBIPOP_01632 2.8e-35 XK27_09805 S MORN repeat protein
KCBBIPOP_01633 0.0 XK27_09800 I Acyltransferase
KCBBIPOP_01634 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KCBBIPOP_01635 0.0 cas3 L CRISPR-associated helicase cas3
KCBBIPOP_01636 0.0 casA L An automated process has identified a potential problem with this gene model
KCBBIPOP_01637 7.5e-106 casB S CRISPR system CASCADE complex protein CasB
KCBBIPOP_01638 1.4e-182 casC L CT1975-like protein
KCBBIPOP_01639 7.7e-137 casD S CRISPR system CASCADE complex protein CasD
KCBBIPOP_01640 3.4e-112 casE S CRISPR system CASCADE complex protein CasE
KCBBIPOP_01641 2.1e-171 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCBBIPOP_01642 1.1e-169 cas2 2.7.7.7 L CRISPR-associated endoribonuclease Cas2
KCBBIPOP_01644 3.2e-234 2.7.13.3 T protein histidine kinase activity
KCBBIPOP_01645 1.1e-215 hpk9 2.7.13.3 T protein histidine kinase activity
KCBBIPOP_01646 7.8e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KCBBIPOP_01647 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KCBBIPOP_01648 1.4e-194 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KCBBIPOP_01649 0.0 lpdA 1.8.1.4 C Dehydrogenase
KCBBIPOP_01650 5e-290 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
KCBBIPOP_01651 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCBBIPOP_01652 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
KCBBIPOP_01653 1.7e-229 ycdB P peroxidase
KCBBIPOP_01654 9.1e-290 ywbL P COG0672 High-affinity Fe2 Pb2 permease
KCBBIPOP_01655 6.4e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCBBIPOP_01656 1e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KCBBIPOP_01657 1e-212 msmX P Belongs to the ABC transporter superfamily
KCBBIPOP_01658 9.8e-152 malG P ABC transporter (Permease
KCBBIPOP_01659 7e-248 malF P ABC transporter (Permease
KCBBIPOP_01660 1.5e-228 malX G ABC transporter
KCBBIPOP_01661 3.5e-180 malR K Transcriptional regulator
KCBBIPOP_01662 8.6e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
KCBBIPOP_01663 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KCBBIPOP_01664 1.2e-38
KCBBIPOP_01665 2.2e-182 lplA 6.3.1.20 H Lipoate-protein ligase
KCBBIPOP_01666 1.1e-192 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KCBBIPOP_01667 0.0 pepN 3.4.11.2 E aminopeptidase
KCBBIPOP_01668 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
KCBBIPOP_01669 5.1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KCBBIPOP_01670 1.5e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KCBBIPOP_01671 9.1e-156 pstA P phosphate transport system permease
KCBBIPOP_01672 9.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
KCBBIPOP_01673 7.6e-155 pstS P phosphate
KCBBIPOP_01674 2.4e-253 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KCBBIPOP_01675 2e-143 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KCBBIPOP_01676 3e-44 yktA S Belongs to the UPF0223 family
KCBBIPOP_01677 1.6e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KCBBIPOP_01678 1.6e-171 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KCBBIPOP_01679 1.8e-145 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KCBBIPOP_01680 7.4e-242 XK27_04775 S hemerythrin HHE cation binding domain
KCBBIPOP_01681 6.1e-35 M1-755 P Hemerythrin HHE cation binding domain protein
KCBBIPOP_01682 6.2e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
KCBBIPOP_01683 4.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KCBBIPOP_01684 3.8e-93 S haloacid dehalogenase-like hydrolase
KCBBIPOP_01685 4.3e-239 metY 2.5.1.49 E o-acetylhomoserine
KCBBIPOP_01686 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KCBBIPOP_01687 4.3e-242 agcS E (Alanine) symporter
KCBBIPOP_01688 1.2e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KCBBIPOP_01689 1.1e-169 bglC K Transcriptional regulator
KCBBIPOP_01690 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KCBBIPOP_01691 2.1e-80 yecS P ABC transporter (Permease
KCBBIPOP_01692 4.6e-149 yckB ET Belongs to the bacterial solute-binding protein 3 family
KCBBIPOP_01693 1.6e-237 nylA 3.5.1.4 J Belongs to the amidase family
KCBBIPOP_01694 1.7e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCBBIPOP_01695 3.5e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KCBBIPOP_01696 4.5e-177 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KCBBIPOP_01697 3.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KCBBIPOP_01698 2e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
KCBBIPOP_01699 1.8e-142 S TraX protein
KCBBIPOP_01700 4e-306 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KCBBIPOP_01701 8.7e-271 S Psort location CytoplasmicMembrane, score
KCBBIPOP_01702 1.9e-234 dinF V Mate efflux family protein
KCBBIPOP_01703 8.9e-181 yclQ P ABC-type enterochelin transport system, periplasmic component
KCBBIPOP_01704 5.5e-167 S von Willebrand factor (vWF) type A domain
KCBBIPOP_01705 1.6e-109 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
KCBBIPOP_01706 9.3e-141 2.4.2.3 F Phosphorylase superfamily
KCBBIPOP_01707 5.3e-145 G protein with an alpha beta hydrolase fold
KCBBIPOP_01708 1.3e-179 S Hydrolases of the alpha beta superfamily
KCBBIPOP_01709 1.6e-157 K Transcriptional regulator
KCBBIPOP_01710 3.8e-111 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
KCBBIPOP_01711 8.1e-32 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
KCBBIPOP_01712 6.7e-201 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KCBBIPOP_01713 3.3e-161 czcD P cation diffusion facilitator family transporter
KCBBIPOP_01714 1.7e-96 K Transcriptional regulator, TetR family
KCBBIPOP_01715 7.2e-67 S Protein of unknown function with HXXEE motif
KCBBIPOP_01716 3.1e-11
KCBBIPOP_01717 2.2e-162 L Transposase
KCBBIPOP_01718 2.8e-134 fasA KT Response regulator of the LytR AlgR family
KCBBIPOP_01719 4.5e-244 fasC 2.7.13.3 T protein histidine kinase activity
KCBBIPOP_01720 7.1e-210 hpk9 2.7.13.3 T protein histidine kinase activity
KCBBIPOP_01721 3.7e-157 hpk9 2.7.13.3 T protein histidine kinase activity
KCBBIPOP_01722 6.7e-232 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KCBBIPOP_01723 3.5e-274 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCBBIPOP_01724 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KCBBIPOP_01725 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KCBBIPOP_01726 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KCBBIPOP_01727 1.2e-50 S Protein of unknown function (DUF3397)
KCBBIPOP_01728 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KCBBIPOP_01729 3.1e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
KCBBIPOP_01730 1.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KCBBIPOP_01731 3.3e-73 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
KCBBIPOP_01732 2e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KCBBIPOP_01733 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
KCBBIPOP_01734 6.7e-229 XK27_09615 C reductase
KCBBIPOP_01735 4.8e-140 fnt P Formate nitrite transporter
KCBBIPOP_01736 3.9e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
KCBBIPOP_01737 3.7e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KCBBIPOP_01738 6.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KCBBIPOP_01739 2e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KCBBIPOP_01740 2.8e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCBBIPOP_01741 7.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KCBBIPOP_01742 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KCBBIPOP_01743 1.8e-141 S HAD hydrolase, family IA, variant
KCBBIPOP_01744 1.2e-160 rrmA 2.1.1.187 Q methyltransferase
KCBBIPOP_01748 3.9e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KCBBIPOP_01749 3.3e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KCBBIPOP_01750 8.3e-37 yeeD O sulfur carrier activity
KCBBIPOP_01751 5.8e-186 yeeE S Sulphur transport
KCBBIPOP_01752 1.1e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KCBBIPOP_01753 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KCBBIPOP_01754 1.6e-08 XK27_10305 S Domain of unknown function (DUF4651)
KCBBIPOP_01755 7.7e-202 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KCBBIPOP_01756 6.1e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCBBIPOP_01757 2.7e-112 S CAAX amino terminal protease family protein
KCBBIPOP_01759 2.5e-110 V CAAX protease self-immunity
KCBBIPOP_01760 8.8e-27 lanR K sequence-specific DNA binding
KCBBIPOP_01761 1.4e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KCBBIPOP_01762 7.7e-177 ytxK 2.1.1.72 L DNA methylase
KCBBIPOP_01763 5.8e-12 comGF U Putative Competence protein ComGF
KCBBIPOP_01764 5.3e-72 comGF U Competence protein ComGF
KCBBIPOP_01765 3.1e-15 NU Type II secretory pathway pseudopilin
KCBBIPOP_01766 6.4e-70 cglD NU Competence protein
KCBBIPOP_01767 2.2e-43 comGC U Required for transformation and DNA binding
KCBBIPOP_01768 1.4e-145 cglB U protein transport across the cell outer membrane
KCBBIPOP_01769 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCBBIPOP_01770 1e-68 S cog cog4699
KCBBIPOP_01771 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCBBIPOP_01772 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCBBIPOP_01773 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCBBIPOP_01774 1.9e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KCBBIPOP_01775 3e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KCBBIPOP_01776 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
KCBBIPOP_01777 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
KCBBIPOP_01778 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KCBBIPOP_01779 3.8e-304 yloV S kinase related to dihydroxyacetone kinase
KCBBIPOP_01780 1.4e-57 asp S cog cog1302
KCBBIPOP_01781 3.2e-226 norN V Mate efflux family protein
KCBBIPOP_01782 1.1e-278 thrC 4.2.3.1 E Threonine synthase
KCBBIPOP_01785 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KCBBIPOP_01786 0.0 pepO 3.4.24.71 O Peptidase family M13
KCBBIPOP_01787 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KCBBIPOP_01788 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KCBBIPOP_01789 6e-126 treR K trehalose operon
KCBBIPOP_01790 4.8e-94 ywlG S Belongs to the UPF0340 family
KCBBIPOP_01793 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
KCBBIPOP_01795 2.7e-241 6.3.2.2 H gamma-glutamylcysteine synthetase
KCBBIPOP_01796 4.4e-62 rplQ J ribosomal protein l17
KCBBIPOP_01797 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCBBIPOP_01798 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KCBBIPOP_01799 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KCBBIPOP_01800 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KCBBIPOP_01801 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KCBBIPOP_01802 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KCBBIPOP_01803 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KCBBIPOP_01804 1.7e-57 rplO J binds to the 23S rRNA
KCBBIPOP_01805 1.9e-23 rpmD J ribosomal protein l30
KCBBIPOP_01806 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KCBBIPOP_01807 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KCBBIPOP_01808 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KCBBIPOP_01809 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KCBBIPOP_01810 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KCBBIPOP_01811 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KCBBIPOP_01812 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KCBBIPOP_01813 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KCBBIPOP_01814 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCBBIPOP_01815 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KCBBIPOP_01816 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KCBBIPOP_01817 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KCBBIPOP_01818 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KCBBIPOP_01819 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KCBBIPOP_01820 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KCBBIPOP_01821 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KCBBIPOP_01822 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
KCBBIPOP_01823 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KCBBIPOP_01824 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
KCBBIPOP_01825 2.7e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCBBIPOP_01826 3.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KCBBIPOP_01827 2.6e-305 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCBBIPOP_01828 1.5e-86 ytsP 1.8.4.14 T GAF domain-containing protein
KCBBIPOP_01829 1.6e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCBBIPOP_01830 6.5e-21 WQ51_02665 S Protein of unknown function (DUF3042)
KCBBIPOP_01831 6.6e-08
KCBBIPOP_01832 7.9e-126 K cell adhesion
KCBBIPOP_01834 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KCBBIPOP_01835 1e-210 XK27_05110 P Chloride transporter ClC family
KCBBIPOP_01836 7.4e-40 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
KCBBIPOP_01837 7.8e-280 clcA P Chloride transporter, ClC family
KCBBIPOP_01838 1e-75 fld C Flavodoxin
KCBBIPOP_01839 6.3e-18 XK27_08880
KCBBIPOP_01840 1.6e-126 XK27_08875 O Zinc-dependent metalloprotease
KCBBIPOP_01841 1.9e-149 estA CE1 S Esterase
KCBBIPOP_01842 1.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCBBIPOP_01843 6.8e-136 XK27_08845 S abc transporter atp-binding protein
KCBBIPOP_01844 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
KCBBIPOP_01845 2.8e-177 XK27_08835 S ABC transporter substrate binding protein
KCBBIPOP_01846 6.4e-18 S Domain of unknown function (DUF4649)
KCBBIPOP_01847 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KCBBIPOP_01848 2.1e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KCBBIPOP_01849 0.0 dnaE 2.7.7.7 L DNA polymerase
KCBBIPOP_01850 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCBBIPOP_01851 3.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCBBIPOP_01852 1.1e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KCBBIPOP_01853 8.4e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCBBIPOP_01854 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KCBBIPOP_01855 1.2e-177 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
KCBBIPOP_01857 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KCBBIPOP_01858 4e-96 ypmS S Protein conserved in bacteria
KCBBIPOP_01859 2.2e-162 ypmR E COG2755 Lysophospholipase L1 and related esterases
KCBBIPOP_01860 2e-144 DegV S DegV family
KCBBIPOP_01861 2.1e-299 recN L May be involved in recombinational repair of damaged DNA
KCBBIPOP_01862 2.8e-73 argR K Regulates arginine biosynthesis genes
KCBBIPOP_01863 4e-145 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KCBBIPOP_01864 2e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KCBBIPOP_01865 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KCBBIPOP_01866 5.2e-232 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KCBBIPOP_01868 3.8e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCBBIPOP_01869 7.2e-124 dnaD
KCBBIPOP_01870 1e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCBBIPOP_01871 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCBBIPOP_01872 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
KCBBIPOP_01873 2e-65 GnaT 2.5.1.16 K acetyltransferase
KCBBIPOP_01874 2.4e-130 Q Methyltransferase domain
KCBBIPOP_01875 1.3e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KCBBIPOP_01876 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KCBBIPOP_01877 6.9e-113 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KCBBIPOP_01878 5.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCBBIPOP_01879 4.6e-226 rodA D Belongs to the SEDS family
KCBBIPOP_01880 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KCBBIPOP_01881 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KCBBIPOP_01882 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KCBBIPOP_01883 1.2e-178 XK27_08075 M glycosyl transferase family 2
KCBBIPOP_01884 4.8e-102 S Carbohydrate-binding domain-containing protein Cthe_2159
KCBBIPOP_01885 2.2e-145 P molecular chaperone
KCBBIPOP_01886 1.1e-92 XK27_05505 S Psort location CytoplasmicMembrane, score
KCBBIPOP_01889 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
KCBBIPOP_01890 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KCBBIPOP_01891 1.4e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KCBBIPOP_01892 5.9e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KCBBIPOP_01893 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KCBBIPOP_01894 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KCBBIPOP_01895 1.9e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KCBBIPOP_01896 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KCBBIPOP_01897 2.9e-179 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KCBBIPOP_01898 1.6e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCBBIPOP_01899 2.7e-61 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCBBIPOP_01900 2.4e-86 L COG1943 Transposase and inactivated derivatives
KCBBIPOP_01901 4.9e-71 2.7.13.3 T Histidine kinase
KCBBIPOP_01902 8.8e-111 K Transcriptional regulatory protein, C terminal
KCBBIPOP_01904 1.9e-48 6.3.5.4 E Asparagine synthase
KCBBIPOP_01906 5.1e-24 S Transglutaminase-like superfamily
KCBBIPOP_01907 3.8e-120 V abc transporter atp-binding protein
KCBBIPOP_01908 3e-17
KCBBIPOP_01910 4.3e-85 V ABC transporter, ATP-binding protein
KCBBIPOP_01911 5.9e-36 K Helix-turn-helix
KCBBIPOP_01912 6.7e-41 D LPXTG cell wall anchor motif
KCBBIPOP_01914 2.2e-94 amiB 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
KCBBIPOP_01916 6.3e-71
KCBBIPOP_01917 1.3e-131 L Integrase
KCBBIPOP_01920 5e-17 S Domain of unknown function (DUF3173)
KCBBIPOP_01921 7e-148 L Phage integrase SAM-like domain
KCBBIPOP_01923 1.3e-65 traG U COG3505 Type IV secretory pathway, VirD4 components
KCBBIPOP_01924 5e-105 XK27_00530 M CHAP domain protein
KCBBIPOP_01925 3.1e-107 abiGI K Transcriptional regulator, AbiEi antitoxin
KCBBIPOP_01926 2.2e-274 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KCBBIPOP_01927 0.0 mdlB V abc transporter atp-binding protein
KCBBIPOP_01928 0.0 lmrA V abc transporter atp-binding protein
KCBBIPOP_01929 1.5e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KCBBIPOP_01930 6.8e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KCBBIPOP_01931 6.9e-197 yceA S Belongs to the UPF0176 family
KCBBIPOP_01932 5.2e-27 XK27_00085 K Transcriptional
KCBBIPOP_01933 3.1e-20
KCBBIPOP_01934 7.3e-113 S VIT family
KCBBIPOP_01935 9.4e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCBBIPOP_01936 5.5e-214 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KCBBIPOP_01937 2.1e-194 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KCBBIPOP_01940 1.4e-126 E Alpha beta hydrolase
KCBBIPOP_01941 9.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCBBIPOP_01942 3.1e-140 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KCBBIPOP_01943 5.3e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KCBBIPOP_01944 6e-164 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KCBBIPOP_01945 1.6e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KCBBIPOP_01946 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KCBBIPOP_01947 2.1e-255 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KCBBIPOP_01948 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
KCBBIPOP_01949 2.9e-25
KCBBIPOP_01950 1.7e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KCBBIPOP_01951 0.0 U protein secretion
KCBBIPOP_01952 2.3e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
KCBBIPOP_01953 4e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KCBBIPOP_01954 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KCBBIPOP_01955 1.8e-170 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KCBBIPOP_01956 5.7e-205 S Protein of unknown function (DUF3114)
KCBBIPOP_01957 9.2e-29 pspC KT PspC domain protein
KCBBIPOP_01958 5.2e-119 yqfA K protein, Hemolysin III
KCBBIPOP_01959 3e-78 K hmm pf08876
KCBBIPOP_01960 4.7e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KCBBIPOP_01961 7.9e-216 mvaS 2.3.3.10 I synthase
KCBBIPOP_01962 5.9e-168 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KCBBIPOP_01963 9.6e-94 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KCBBIPOP_01964 9.7e-22
KCBBIPOP_01965 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KCBBIPOP_01966 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
KCBBIPOP_01967 1.2e-250 mmuP E amino acid
KCBBIPOP_01968 1.7e-171 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KCBBIPOP_01969 2.2e-30 S Domain of unknown function (DUF1912)
KCBBIPOP_01970 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
KCBBIPOP_01971 1.8e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KCBBIPOP_01972 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KCBBIPOP_01974 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KCBBIPOP_01975 2.6e-199 ilvE 2.6.1.42 E Aminotransferase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)