ORF_ID e_value Gene_name EC_number CAZy COGs Description
JHOFNEDM_00001 1e-72 C FMN binding
JHOFNEDM_00002 5.7e-158 K LysR family
JHOFNEDM_00003 1.6e-258 P Sodium:sulfate symporter transmembrane region
JHOFNEDM_00004 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
JHOFNEDM_00005 2e-115 S Elongation factor G-binding protein, N-terminal
JHOFNEDM_00006 5.8e-64 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
JHOFNEDM_00007 9.1e-121 pnb C nitroreductase
JHOFNEDM_00008 6.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
JHOFNEDM_00009 4.4e-261 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
JHOFNEDM_00010 1.5e-95 K Bacterial regulatory proteins, tetR family
JHOFNEDM_00011 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JHOFNEDM_00012 6.8e-173 htrA 3.4.21.107 O serine protease
JHOFNEDM_00013 8.9e-158 vicX 3.1.26.11 S domain protein
JHOFNEDM_00014 2.9e-151 yycI S YycH protein
JHOFNEDM_00015 2e-244 yycH S YycH protein
JHOFNEDM_00016 0.0 vicK 2.7.13.3 T Histidine kinase
JHOFNEDM_00017 6.2e-131 K response regulator
JHOFNEDM_00019 1.7e-37
JHOFNEDM_00020 1.6e-31 cspA K Cold shock protein domain
JHOFNEDM_00021 2e-32 S Pyridoxamine 5'-phosphate oxidase
JHOFNEDM_00022 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
JHOFNEDM_00023 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
JHOFNEDM_00024 4.5e-143 S haloacid dehalogenase-like hydrolase
JHOFNEDM_00026 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
JHOFNEDM_00027 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
JHOFNEDM_00028 8.1e-279 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
JHOFNEDM_00029 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
JHOFNEDM_00030 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JHOFNEDM_00031 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JHOFNEDM_00033 1.9e-276 E ABC transporter, substratebinding protein
JHOFNEDM_00035 5e-229 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JHOFNEDM_00036 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JHOFNEDM_00037 8.8e-226 yttB EGP Major facilitator Superfamily
JHOFNEDM_00038 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JHOFNEDM_00039 1.4e-67 rplI J Binds to the 23S rRNA
JHOFNEDM_00040 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JHOFNEDM_00041 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JHOFNEDM_00042 6.8e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JHOFNEDM_00043 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
JHOFNEDM_00044 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JHOFNEDM_00045 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JHOFNEDM_00046 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JHOFNEDM_00047 5e-37 yaaA S S4 domain protein YaaA
JHOFNEDM_00048 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JHOFNEDM_00049 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JHOFNEDM_00050 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JHOFNEDM_00051 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JHOFNEDM_00052 2e-310 E ABC transporter, substratebinding protein
JHOFNEDM_00053 1.8e-237 Q Imidazolonepropionase and related amidohydrolases
JHOFNEDM_00054 2.1e-129 jag S R3H domain protein
JHOFNEDM_00055 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JHOFNEDM_00056 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JHOFNEDM_00057 6.9e-93 S Cell surface protein
JHOFNEDM_00058 1.2e-159 S Bacterial protein of unknown function (DUF916)
JHOFNEDM_00060 1.3e-303
JHOFNEDM_00061 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JHOFNEDM_00063 1.5e-255 pepC 3.4.22.40 E aminopeptidase
JHOFNEDM_00064 2.4e-58 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
JHOFNEDM_00065 1.2e-157 degV S DegV family
JHOFNEDM_00066 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
JHOFNEDM_00067 4.4e-141 tesE Q hydratase
JHOFNEDM_00068 3.2e-103 padC Q Phenolic acid decarboxylase
JHOFNEDM_00069 2.2e-99 padR K Virulence activator alpha C-term
JHOFNEDM_00070 2.7e-79 T Universal stress protein family
JHOFNEDM_00071 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JHOFNEDM_00072 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
JHOFNEDM_00073 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHOFNEDM_00074 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
JHOFNEDM_00075 2.7e-160 rbsU U ribose uptake protein RbsU
JHOFNEDM_00076 1.5e-144 IQ NAD dependent epimerase/dehydratase family
JHOFNEDM_00077 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
JHOFNEDM_00078 1.1e-86 gutM K Glucitol operon activator protein (GutM)
JHOFNEDM_00079 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
JHOFNEDM_00080 1e-174 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
JHOFNEDM_00081 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
JHOFNEDM_00082 6.8e-156 lrp QT PucR C-terminal helix-turn-helix domain
JHOFNEDM_00083 2.2e-193 rliB K helix_turn_helix gluconate operon transcriptional repressor
JHOFNEDM_00084 2.5e-311 yknV V ABC transporter
JHOFNEDM_00085 0.0 mdlA2 V ABC transporter
JHOFNEDM_00086 6.5e-156 K AraC-like ligand binding domain
JHOFNEDM_00087 0.0 3.2.1.52 GH20 G Glycosyl hydrolase family 20, catalytic domain
JHOFNEDM_00088 5.2e-181 U Binding-protein-dependent transport system inner membrane component
JHOFNEDM_00089 1.3e-160 lplC U Binding-protein-dependent transport system inner membrane component
JHOFNEDM_00090 9.8e-280 G Domain of unknown function (DUF3502)
JHOFNEDM_00091 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
JHOFNEDM_00092 4.1e-107 ypcB S integral membrane protein
JHOFNEDM_00093 0.0 yesM 2.7.13.3 T Histidine kinase
JHOFNEDM_00094 6.3e-271 yesN K helix_turn_helix, arabinose operon control protein
JHOFNEDM_00095 2.1e-165 scrK 2.7.1.2, 2.7.1.4 GK ROK family
JHOFNEDM_00096 9.1e-217 msmX P Belongs to the ABC transporter superfamily
JHOFNEDM_00097 0.0 ypdD G Glycosyl hydrolase family 92
JHOFNEDM_00098 1e-193 rliB K Transcriptional regulator
JHOFNEDM_00099 1.2e-252 S Metal-independent alpha-mannosidase (GH125)
JHOFNEDM_00100 0.0 mngB 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
JHOFNEDM_00101 3.9e-159 ypbG 2.7.1.2 GK ROK family
JHOFNEDM_00102 1.9e-285 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHOFNEDM_00103 4.8e-20
JHOFNEDM_00104 5.4e-74 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
JHOFNEDM_00105 3.6e-28 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
JHOFNEDM_00106 5.9e-105 M Glycosyl hydrolases family 25
JHOFNEDM_00108 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JHOFNEDM_00109 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHOFNEDM_00110 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JHOFNEDM_00111 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JHOFNEDM_00112 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JHOFNEDM_00113 2.2e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JHOFNEDM_00114 3.1e-74 yabR J RNA binding
JHOFNEDM_00115 1.1e-63 divIC D Septum formation initiator
JHOFNEDM_00117 2.2e-42 yabO J S4 domain protein
JHOFNEDM_00118 3.3e-289 yabM S Polysaccharide biosynthesis protein
JHOFNEDM_00119 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JHOFNEDM_00120 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JHOFNEDM_00121 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JHOFNEDM_00122 2.4e-264 S Putative peptidoglycan binding domain
JHOFNEDM_00123 2.1e-114 S (CBS) domain
JHOFNEDM_00124 4.1e-84 S QueT transporter
JHOFNEDM_00125 9.4e-189 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JHOFNEDM_00126 4.6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine
JHOFNEDM_00127 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
JHOFNEDM_00128 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JHOFNEDM_00129 3e-187 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JHOFNEDM_00130 6.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JHOFNEDM_00131 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
JHOFNEDM_00132 5e-134 P ATPases associated with a variety of cellular activities
JHOFNEDM_00133 6.3e-129 ssuC2 U Binding-protein-dependent transport system inner membrane component
JHOFNEDM_00134 2.9e-193 P ABC transporter, substratebinding protein
JHOFNEDM_00135 0.0 kup P Transport of potassium into the cell
JHOFNEDM_00136 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
JHOFNEDM_00137 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHOFNEDM_00138 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JHOFNEDM_00139 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JHOFNEDM_00140 1.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JHOFNEDM_00141 2e-146
JHOFNEDM_00142 2.1e-139 htpX O Belongs to the peptidase M48B family
JHOFNEDM_00143 1.7e-91 lemA S LemA family
JHOFNEDM_00144 9.2e-127 srtA 3.4.22.70 M sortase family
JHOFNEDM_00145 5.1e-212 J translation release factor activity
JHOFNEDM_00146 7.8e-41 rpmE2 J Ribosomal protein L31
JHOFNEDM_00147 8.7e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JHOFNEDM_00148 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JHOFNEDM_00149 5.1e-27
JHOFNEDM_00150 1.1e-130 S YheO-like PAS domain
JHOFNEDM_00151 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
JHOFNEDM_00152 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
JHOFNEDM_00153 3.1e-229 tdcC E amino acid
JHOFNEDM_00154 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JHOFNEDM_00155 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JHOFNEDM_00156 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JHOFNEDM_00157 3.8e-78 ywiB S Domain of unknown function (DUF1934)
JHOFNEDM_00158 1.4e-153 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
JHOFNEDM_00159 2.6e-263 ywfO S HD domain protein
JHOFNEDM_00160 3.7e-148 yxeH S hydrolase
JHOFNEDM_00161 4.1e-125
JHOFNEDM_00162 2.4e-184 S DUF218 domain
JHOFNEDM_00163 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JHOFNEDM_00164 1.8e-150 bla1 3.5.2.6 V Beta-lactamase enzyme family
JHOFNEDM_00165 1.2e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JHOFNEDM_00166 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
JHOFNEDM_00167 2.1e-31
JHOFNEDM_00168 6.4e-43 ankB S ankyrin repeats
JHOFNEDM_00169 9.2e-131 znuB U ABC 3 transport family
JHOFNEDM_00170 9.8e-129 fhuC 3.6.3.35 P ABC transporter
JHOFNEDM_00171 1.3e-181 S Prolyl oligopeptidase family
JHOFNEDM_00172 5.7e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JHOFNEDM_00173 3.2e-37 veg S Biofilm formation stimulator VEG
JHOFNEDM_00174 8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JHOFNEDM_00175 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JHOFNEDM_00176 5.7e-146 tatD L hydrolase, TatD family
JHOFNEDM_00177 1.3e-210 bcr1 EGP Major facilitator Superfamily
JHOFNEDM_00178 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHOFNEDM_00179 5.2e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
JHOFNEDM_00180 2e-160 yunF F Protein of unknown function DUF72
JHOFNEDM_00181 2.5e-132 cobB K SIR2 family
JHOFNEDM_00182 3.1e-178
JHOFNEDM_00183 8.9e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
JHOFNEDM_00184 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
JHOFNEDM_00185 3.5e-151 S Psort location Cytoplasmic, score
JHOFNEDM_00186 1.1e-206
JHOFNEDM_00187 8.1e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHOFNEDM_00188 4.1e-133 K Helix-turn-helix domain, rpiR family
JHOFNEDM_00189 1e-162 GK ROK family
JHOFNEDM_00190 2.8e-295 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHOFNEDM_00191 1.5e-250 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHOFNEDM_00192 2.6e-76 S Domain of unknown function (DUF3284)
JHOFNEDM_00193 3.9e-24
JHOFNEDM_00194 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHOFNEDM_00195 4.5e-129 K UbiC transcription regulator-associated domain protein
JHOFNEDM_00196 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
JHOFNEDM_00197 1.2e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
JHOFNEDM_00198 0.0 helD 3.6.4.12 L DNA helicase
JHOFNEDM_00199 2.6e-29
JHOFNEDM_00200 1e-114 S CAAX protease self-immunity
JHOFNEDM_00201 4.7e-112 V CAAX protease self-immunity
JHOFNEDM_00202 1.6e-120 ypbD S CAAX protease self-immunity
JHOFNEDM_00203 5.5e-95 S CAAX protease self-immunity
JHOFNEDM_00204 1.4e-243 mesE M Transport protein ComB
JHOFNEDM_00205 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JHOFNEDM_00206 6.7e-23
JHOFNEDM_00207 2.4e-22 plnF
JHOFNEDM_00208 2.2e-129 S CAAX protease self-immunity
JHOFNEDM_00209 3.7e-134 plnD K LytTr DNA-binding domain
JHOFNEDM_00210 9.1e-133 plnC K LytTr DNA-binding domain
JHOFNEDM_00211 1e-235 plnB 2.7.13.3 T GHKL domain
JHOFNEDM_00212 4e-09
JHOFNEDM_00214 1.1e-53
JHOFNEDM_00215 8.1e-28
JHOFNEDM_00216 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
JHOFNEDM_00217 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
JHOFNEDM_00218 5.8e-48 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
JHOFNEDM_00219 7.9e-41
JHOFNEDM_00220 4.3e-67 tspO T TspO/MBR family
JHOFNEDM_00221 1.4e-75 uspA T Belongs to the universal stress protein A family
JHOFNEDM_00222 8e-66 S Protein of unknown function (DUF805)
JHOFNEDM_00223 1.8e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
JHOFNEDM_00224 3.5e-36
JHOFNEDM_00225 3.1e-14
JHOFNEDM_00226 6.5e-41 S transglycosylase associated protein
JHOFNEDM_00227 4.8e-29 S CsbD-like
JHOFNEDM_00228 9.4e-40
JHOFNEDM_00229 1.6e-279 pipD E Dipeptidase
JHOFNEDM_00230 5.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
JHOFNEDM_00231 5.7e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JHOFNEDM_00232 1e-170 2.5.1.74 H UbiA prenyltransferase family
JHOFNEDM_00233 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
JHOFNEDM_00234 3.9e-50
JHOFNEDM_00235 1.3e-42
JHOFNEDM_00236 8.7e-259 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHOFNEDM_00237 1.4e-265 yfnA E Amino Acid
JHOFNEDM_00238 1.2e-149 yitU 3.1.3.104 S hydrolase
JHOFNEDM_00239 5.5e-269 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
JHOFNEDM_00240 5.2e-79 S Domain of unknown function (DUF4767)
JHOFNEDM_00241 2.5e-250 malT G Major Facilitator
JHOFNEDM_00242 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
JHOFNEDM_00243 6.2e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JHOFNEDM_00244 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JHOFNEDM_00245 7.6e-205 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
JHOFNEDM_00246 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
JHOFNEDM_00247 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
JHOFNEDM_00248 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JHOFNEDM_00249 2.1e-72 ypmB S protein conserved in bacteria
JHOFNEDM_00250 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JHOFNEDM_00251 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
JHOFNEDM_00252 1.3e-128 dnaD L Replication initiation and membrane attachment
JHOFNEDM_00253 2.4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JHOFNEDM_00254 2e-99 metI P ABC transporter permease
JHOFNEDM_00255 5.5e-158 metQ_4 P Belongs to the nlpA lipoprotein family
JHOFNEDM_00256 2e-83 uspA T Universal stress protein family
JHOFNEDM_00257 2e-147 ftpA P Binding-protein-dependent transport system inner membrane component
JHOFNEDM_00258 2.5e-141 ftpA P Binding-protein-dependent transport system inner membrane component
JHOFNEDM_00259 3.8e-182 ftpB P Bacterial extracellular solute-binding protein
JHOFNEDM_00260 7.4e-180 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
JHOFNEDM_00261 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
JHOFNEDM_00262 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JHOFNEDM_00263 8.3e-110 ypsA S Belongs to the UPF0398 family
JHOFNEDM_00264 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JHOFNEDM_00266 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JHOFNEDM_00267 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
JHOFNEDM_00268 2.5e-181 P Major Facilitator Superfamily
JHOFNEDM_00269 8.9e-51 P Major Facilitator Superfamily
JHOFNEDM_00270 8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
JHOFNEDM_00271 9.9e-73 S SnoaL-like domain
JHOFNEDM_00272 1.9e-200 M Glycosyltransferase, group 2 family protein
JHOFNEDM_00273 3.6e-207 mccF V LD-carboxypeptidase
JHOFNEDM_00274 2.5e-75 K Acetyltransferase (GNAT) domain
JHOFNEDM_00275 4.5e-239 M hydrolase, family 25
JHOFNEDM_00276 1.6e-182 mccF 3.4.17.13 V LD-carboxypeptidase
JHOFNEDM_00277 1.7e-73 XK27_05710 K Acetyltransferase (GNAT) domain
JHOFNEDM_00278 7.3e-122
JHOFNEDM_00279 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
JHOFNEDM_00280 2.1e-194
JHOFNEDM_00281 1.5e-146 S hydrolase activity, acting on ester bonds
JHOFNEDM_00282 9.5e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
JHOFNEDM_00283 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
JHOFNEDM_00284 2.2e-61 esbA S Family of unknown function (DUF5322)
JHOFNEDM_00285 2.1e-294 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
JHOFNEDM_00286 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JHOFNEDM_00287 1e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JHOFNEDM_00288 1.3e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JHOFNEDM_00289 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
JHOFNEDM_00290 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
JHOFNEDM_00291 8.8e-288 S Bacterial membrane protein, YfhO
JHOFNEDM_00292 5.5e-112 pgm5 G Phosphoglycerate mutase family
JHOFNEDM_00293 5.8e-70 frataxin S Domain of unknown function (DU1801)
JHOFNEDM_00295 4.6e-128 cat 2.3.1.28 V Chloramphenicol acetyltransferase
JHOFNEDM_00296 3.5e-69 S LuxR family transcriptional regulator
JHOFNEDM_00297 3.6e-134 S Uncharacterized protein conserved in bacteria (DUF2087)
JHOFNEDM_00299 2.2e-90 3.6.1.55 F NUDIX domain
JHOFNEDM_00300 1.5e-57 V ABC transporter, ATP-binding protein
JHOFNEDM_00301 0.0 FbpA K Fibronectin-binding protein
JHOFNEDM_00302 1.9e-66 K Transcriptional regulator
JHOFNEDM_00303 2.1e-160 degV S EDD domain protein, DegV family
JHOFNEDM_00304 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
JHOFNEDM_00305 3.4e-132 S Protein of unknown function (DUF975)
JHOFNEDM_00306 4.3e-10
JHOFNEDM_00307 1.4e-49
JHOFNEDM_00308 1.6e-148 2.7.7.12 C Domain of unknown function (DUF4931)
JHOFNEDM_00309 1.6e-211 pmrB EGP Major facilitator Superfamily
JHOFNEDM_00310 4.6e-12
JHOFNEDM_00311 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
JHOFNEDM_00312 1.5e-128 yejC S Protein of unknown function (DUF1003)
JHOFNEDM_00313 2.5e-134 XK27_00890 S Domain of unknown function (DUF368)
JHOFNEDM_00314 5.4e-245 cycA E Amino acid permease
JHOFNEDM_00315 3.5e-123
JHOFNEDM_00316 4.1e-59
JHOFNEDM_00317 1.8e-279 lldP C L-lactate permease
JHOFNEDM_00318 2.6e-226
JHOFNEDM_00319 3.7e-128 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
JHOFNEDM_00320 7.7e-191 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
JHOFNEDM_00321 8.6e-196 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
JHOFNEDM_00322 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
JHOFNEDM_00323 8.5e-93 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
JHOFNEDM_00324 1.8e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
JHOFNEDM_00325 2e-239 gshR1 1.8.1.7 C Glutathione reductase
JHOFNEDM_00326 1.3e-129 tcyA ET Belongs to the bacterial solute-binding protein 3 family
JHOFNEDM_00327 3.8e-78 KT response to antibiotic
JHOFNEDM_00328 1.5e-52 K Transcriptional regulator
JHOFNEDM_00329 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
JHOFNEDM_00330 1.7e-128 S Putative adhesin
JHOFNEDM_00331 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
JHOFNEDM_00332 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
JHOFNEDM_00333 3.7e-182 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
JHOFNEDM_00334 2.2e-204 S DUF218 domain
JHOFNEDM_00335 2e-127 ybbM S Uncharacterised protein family (UPF0014)
JHOFNEDM_00336 9.4e-118 ybbL S ABC transporter, ATP-binding protein
JHOFNEDM_00337 1.2e-274 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JHOFNEDM_00338 9.4e-77
JHOFNEDM_00339 3.4e-152 qorB 1.6.5.2 GM NmrA-like family
JHOFNEDM_00340 1.4e-147 cof S haloacid dehalogenase-like hydrolase
JHOFNEDM_00341 5.3e-92 scrK 2.7.1.2, 2.7.1.4 GK ROK family
JHOFNEDM_00342 1.5e-307 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
JHOFNEDM_00343 2.8e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
JHOFNEDM_00344 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
JHOFNEDM_00345 2.9e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
JHOFNEDM_00346 2.2e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JHOFNEDM_00347 2e-77 merR K MerR family regulatory protein
JHOFNEDM_00348 1.4e-156 1.6.5.2 GM NmrA-like family
JHOFNEDM_00349 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
JHOFNEDM_00350 3.9e-127 magIII L Base excision DNA repair protein, HhH-GPD family
JHOFNEDM_00351 1.4e-08
JHOFNEDM_00352 2e-100 S NADPH-dependent FMN reductase
JHOFNEDM_00353 7.9e-238 S module of peptide synthetase
JHOFNEDM_00354 4.2e-104
JHOFNEDM_00355 9.8e-88 perR P Belongs to the Fur family
JHOFNEDM_00356 7.1e-59 S Enterocin A Immunity
JHOFNEDM_00357 5.4e-36 S Phospholipase_D-nuclease N-terminal
JHOFNEDM_00358 1.8e-169 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
JHOFNEDM_00359 3.8e-104 J Acetyltransferase (GNAT) domain
JHOFNEDM_00360 5.1e-64 lrgA S LrgA family
JHOFNEDM_00361 7.3e-127 lrgB M LrgB-like family
JHOFNEDM_00362 2.5e-145 DegV S EDD domain protein, DegV family
JHOFNEDM_00363 4.1e-25
JHOFNEDM_00364 3.5e-118 yugP S Putative neutral zinc metallopeptidase
JHOFNEDM_00365 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
JHOFNEDM_00366 7.4e-166 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
JHOFNEDM_00367 1.7e-184 D Alpha beta
JHOFNEDM_00368 7.1e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JHOFNEDM_00369 8.1e-257 gor 1.8.1.7 C Glutathione reductase
JHOFNEDM_00370 3.4e-55 S Enterocin A Immunity
JHOFNEDM_00371 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JHOFNEDM_00372 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JHOFNEDM_00373 3.5e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JHOFNEDM_00374 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
JHOFNEDM_00375 4.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHOFNEDM_00377 3.1e-81
JHOFNEDM_00378 1.5e-256 yhdG E C-terminus of AA_permease
JHOFNEDM_00380 0.0 kup P Transport of potassium into the cell
JHOFNEDM_00381 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JHOFNEDM_00382 9e-179 K AI-2E family transporter
JHOFNEDM_00383 4e-217 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
JHOFNEDM_00384 4.4e-59 qacC P Small Multidrug Resistance protein
JHOFNEDM_00385 1.1e-44 qacH U Small Multidrug Resistance protein
JHOFNEDM_00386 3e-116 hly S protein, hemolysin III
JHOFNEDM_00387 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
JHOFNEDM_00388 2.7e-160 czcD P cation diffusion facilitator family transporter
JHOFNEDM_00389 2.7e-103 K Helix-turn-helix XRE-family like proteins
JHOFNEDM_00391 2.1e-21
JHOFNEDM_00393 6.5e-96 tag 3.2.2.20 L glycosylase
JHOFNEDM_00394 1.2e-213 folP 2.5.1.15 H dihydropteroate synthase
JHOFNEDM_00395 1.7e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
JHOFNEDM_00396 4.8e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JHOFNEDM_00397 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
JHOFNEDM_00398 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
JHOFNEDM_00399 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JHOFNEDM_00400 4.7e-83 cvpA S Colicin V production protein
JHOFNEDM_00401 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
JHOFNEDM_00402 8.6e-249 EGP Major facilitator Superfamily
JHOFNEDM_00404 7e-40
JHOFNEDM_00405 5.8e-12 S TfoX C-terminal domain
JHOFNEDM_00406 1.5e-226 hpk9 2.7.13.3 T GHKL domain
JHOFNEDM_00407 8.4e-263
JHOFNEDM_00408 8.4e-75
JHOFNEDM_00409 8e-183 S Cell surface protein
JHOFNEDM_00410 5.1e-101 S WxL domain surface cell wall-binding
JHOFNEDM_00411 1.7e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
JHOFNEDM_00412 9.3e-68 S Iron-sulphur cluster biosynthesis
JHOFNEDM_00413 6.6e-116 S GyrI-like small molecule binding domain
JHOFNEDM_00414 3.6e-188 S Cell surface protein
JHOFNEDM_00416 1.7e-100 S WxL domain surface cell wall-binding
JHOFNEDM_00417 1.1e-62
JHOFNEDM_00418 2.1e-219 NU Mycoplasma protein of unknown function, DUF285
JHOFNEDM_00419 5.9e-117
JHOFNEDM_00420 5.7e-115 S Haloacid dehalogenase-like hydrolase
JHOFNEDM_00421 2e-61 K Transcriptional regulator, HxlR family
JHOFNEDM_00422 4.9e-213 ytbD EGP Major facilitator Superfamily
JHOFNEDM_00423 1.4e-94 M ErfK YbiS YcfS YnhG
JHOFNEDM_00424 0.0 asnB 6.3.5.4 E Asparagine synthase
JHOFNEDM_00425 1.7e-134 K LytTr DNA-binding domain
JHOFNEDM_00426 3e-205 2.7.13.3 T GHKL domain
JHOFNEDM_00427 7.9e-100 fadR K Bacterial regulatory proteins, tetR family
JHOFNEDM_00428 2.8e-168 GM NmrA-like family
JHOFNEDM_00429 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
JHOFNEDM_00430 0.0 M Glycosyl hydrolases family 25
JHOFNEDM_00431 1e-47 S Domain of unknown function (DUF1905)
JHOFNEDM_00432 3.7e-63 hxlR K HxlR-like helix-turn-helix
JHOFNEDM_00433 9.8e-132 ydfG S KR domain
JHOFNEDM_00434 1.2e-95 K Bacterial regulatory proteins, tetR family
JHOFNEDM_00435 1.2e-191 1.1.1.219 GM Male sterility protein
JHOFNEDM_00436 4.1e-101 S Protein of unknown function (DUF1211)
JHOFNEDM_00437 1.5e-180 S Aldo keto reductase
JHOFNEDM_00438 4.9e-180 yfjF U Sugar (and other) transporter
JHOFNEDM_00439 2.9e-64 yfjF U Sugar (and other) transporter
JHOFNEDM_00440 7.4e-109 K Bacterial regulatory proteins, tetR family
JHOFNEDM_00441 4e-170 fhuD P Periplasmic binding protein
JHOFNEDM_00442 4.6e-143 fhuC 3.6.3.34 HP ABC transporter
JHOFNEDM_00443 2.1e-177 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHOFNEDM_00444 3.9e-171 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHOFNEDM_00445 5.4e-92 K Bacterial regulatory proteins, tetR family
JHOFNEDM_00446 2.9e-162 GM NmrA-like family
JHOFNEDM_00447 1.2e-129 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JHOFNEDM_00448 1.3e-68 maa S transferase hexapeptide repeat
JHOFNEDM_00449 7.5e-152 IQ Enoyl-(Acyl carrier protein) reductase
JHOFNEDM_00450 1.6e-64 K helix_turn_helix, mercury resistance
JHOFNEDM_00451 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
JHOFNEDM_00452 8.6e-177 S Bacterial protein of unknown function (DUF916)
JHOFNEDM_00453 9.6e-90 S WxL domain surface cell wall-binding
JHOFNEDM_00454 5.4e-189 NU Mycoplasma protein of unknown function, DUF285
JHOFNEDM_00455 2.1e-117 K Bacterial regulatory proteins, tetR family
JHOFNEDM_00456 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JHOFNEDM_00457 1.3e-290 yjcE P Sodium proton antiporter
JHOFNEDM_00458 4.3e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
JHOFNEDM_00459 7.9e-163 K LysR substrate binding domain
JHOFNEDM_00460 1.7e-284 1.3.5.4 C FAD binding domain
JHOFNEDM_00461 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
JHOFNEDM_00462 1.9e-30
JHOFNEDM_00464 1.9e-147 licT2 K CAT RNA binding domain
JHOFNEDM_00465 1.9e-291 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHOFNEDM_00466 0.0 bglF 2.7.1.193, 2.7.1.211 G phosphotransferase system
JHOFNEDM_00467 1.1e-65 S Protein of unknown function (DUF1093)
JHOFNEDM_00468 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JHOFNEDM_00469 5.8e-234 ulaA 2.7.1.194 S PTS system sugar-specific permease component
JHOFNEDM_00470 1.4e-47 ulaB 2.7.1.194, 2.7.1.200 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHOFNEDM_00471 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JHOFNEDM_00472 2e-209 S Membrane
JHOFNEDM_00473 6.5e-44 S Protein of unknown function (DUF3781)
JHOFNEDM_00474 2.7e-108 ydeA S intracellular protease amidase
JHOFNEDM_00475 1.5e-42 K HxlR-like helix-turn-helix
JHOFNEDM_00476 7.2e-42 C Alcohol dehydrogenase GroES-like domain
JHOFNEDM_00477 7.2e-95 C Alcohol dehydrogenase GroES-like domain
JHOFNEDM_00478 5.8e-205 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
JHOFNEDM_00480 8.1e-84 3.2.1.17, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JHOFNEDM_00481 4.2e-71 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JHOFNEDM_00482 1.2e-104 M ErfK YbiS YcfS YnhG
JHOFNEDM_00483 2.3e-101 akr5f 1.1.1.346 S reductase
JHOFNEDM_00484 4.6e-35 S aldo-keto reductase (NADP) activity
JHOFNEDM_00485 3.3e-109 GM NAD(P)H-binding
JHOFNEDM_00486 2.2e-78 3.5.4.1 GM SnoaL-like domain
JHOFNEDM_00487 6.5e-260 qacA EGP Fungal trichothecene efflux pump (TRI12)
JHOFNEDM_00488 1.6e-64 S Domain of unknown function (DUF4440)
JHOFNEDM_00489 2.4e-104 K Bacterial regulatory proteins, tetR family
JHOFNEDM_00491 6.8e-33 L transposase activity
JHOFNEDM_00493 8.8e-40
JHOFNEDM_00494 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JHOFNEDM_00495 1.9e-171 K AI-2E family transporter
JHOFNEDM_00496 2.9e-210 xylR GK ROK family
JHOFNEDM_00497 2.1e-79
JHOFNEDM_00498 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
JHOFNEDM_00499 3.9e-162
JHOFNEDM_00500 3.2e-200 KLT Protein tyrosine kinase
JHOFNEDM_00501 2.9e-23 S Protein of unknown function (DUF4064)
JHOFNEDM_00502 6e-97 S Domain of unknown function (DUF4352)
JHOFNEDM_00503 3.9e-75 S Psort location Cytoplasmic, score
JHOFNEDM_00504 4.8e-55
JHOFNEDM_00505 3.6e-110 S membrane transporter protein
JHOFNEDM_00506 2.3e-54 azlD S branched-chain amino acid
JHOFNEDM_00507 5.1e-131 azlC E branched-chain amino acid
JHOFNEDM_00508 1.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
JHOFNEDM_00509 4.9e-238 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JHOFNEDM_00510 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
JHOFNEDM_00511 3.2e-124 K response regulator
JHOFNEDM_00512 5.5e-124 yoaK S Protein of unknown function (DUF1275)
JHOFNEDM_00513 2.9e-160 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JHOFNEDM_00514 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JHOFNEDM_00515 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
JHOFNEDM_00516 9.8e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JHOFNEDM_00517 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
JHOFNEDM_00518 4.8e-157 spo0J K Belongs to the ParB family
JHOFNEDM_00519 1.8e-136 soj D Sporulation initiation inhibitor
JHOFNEDM_00520 2.7e-149 noc K Belongs to the ParB family
JHOFNEDM_00521 1.7e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
JHOFNEDM_00522 4.1e-226 nupG F Nucleoside
JHOFNEDM_00523 0.0 S Bacterial membrane protein YfhO
JHOFNEDM_00524 4.3e-147 S Alpha/beta hydrolase of unknown function (DUF915)
JHOFNEDM_00525 2.1e-168 K LysR substrate binding domain
JHOFNEDM_00526 5.5e-236 EK Aminotransferase, class I
JHOFNEDM_00527 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
JHOFNEDM_00528 8.1e-123 tcyB E ABC transporter
JHOFNEDM_00529 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JHOFNEDM_00530 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JHOFNEDM_00531 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JHOFNEDM_00532 1.6e-120 S Repeat protein
JHOFNEDM_00533 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
JHOFNEDM_00534 3.8e-268 N domain, Protein
JHOFNEDM_00535 1.7e-193 S Bacterial protein of unknown function (DUF916)
JHOFNEDM_00536 5.1e-120 N WxL domain surface cell wall-binding
JHOFNEDM_00537 4.5e-115 ktrA P domain protein
JHOFNEDM_00538 1.3e-241 ktrB P Potassium uptake protein
JHOFNEDM_00539 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JHOFNEDM_00540 4.9e-57 XK27_04120 S Putative amino acid metabolism
JHOFNEDM_00541 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
JHOFNEDM_00542 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JHOFNEDM_00543 4.6e-28
JHOFNEDM_00544 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
JHOFNEDM_00545 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JHOFNEDM_00546 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JHOFNEDM_00547 1.2e-86 divIVA D DivIVA domain protein
JHOFNEDM_00548 3.4e-146 ylmH S S4 domain protein
JHOFNEDM_00549 1.2e-36 yggT S YGGT family
JHOFNEDM_00550 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JHOFNEDM_00551 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JHOFNEDM_00552 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JHOFNEDM_00553 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JHOFNEDM_00554 5.9e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JHOFNEDM_00555 1.4e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JHOFNEDM_00556 2.4e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JHOFNEDM_00557 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
JHOFNEDM_00558 7.5e-54 ftsL D Cell division protein FtsL
JHOFNEDM_00559 2.9e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JHOFNEDM_00560 1.9e-77 mraZ K Belongs to the MraZ family
JHOFNEDM_00561 1.9e-62 S Protein of unknown function (DUF3397)
JHOFNEDM_00562 4.2e-175 corA P CorA-like Mg2+ transporter protein
JHOFNEDM_00563 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JHOFNEDM_00564 1.4e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JHOFNEDM_00565 1.8e-113 ywnB S NAD(P)H-binding
JHOFNEDM_00566 3.7e-209 brnQ U Component of the transport system for branched-chain amino acids
JHOFNEDM_00568 1.1e-161 rrmA 2.1.1.187 H Methyltransferase
JHOFNEDM_00569 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JHOFNEDM_00570 4.3e-206 XK27_05220 S AI-2E family transporter
JHOFNEDM_00571 2.2e-55 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
JHOFNEDM_00572 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
JHOFNEDM_00573 5.1e-116 cutC P Participates in the control of copper homeostasis
JHOFNEDM_00574 8.9e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
JHOFNEDM_00575 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JHOFNEDM_00576 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
JHOFNEDM_00577 3.6e-114 yjbH Q Thioredoxin
JHOFNEDM_00578 0.0 pepF E oligoendopeptidase F
JHOFNEDM_00579 3.5e-202 coiA 3.6.4.12 S Competence protein
JHOFNEDM_00580 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
JHOFNEDM_00581 7.9e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JHOFNEDM_00582 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
JHOFNEDM_00583 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
JHOFNEDM_00593 5.5e-08
JHOFNEDM_00604 4.2e-43
JHOFNEDM_00605 8.7e-93 K Transcriptional regulator PadR-like family
JHOFNEDM_00606 3.5e-258 P Major Facilitator Superfamily
JHOFNEDM_00607 1.8e-240 amtB P ammonium transporter
JHOFNEDM_00608 1.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
JHOFNEDM_00609 3.7e-44
JHOFNEDM_00610 6.3e-102 zmp1 O Zinc-dependent metalloprotease
JHOFNEDM_00611 4.6e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
JHOFNEDM_00612 1.5e-310 mco Q Multicopper oxidase
JHOFNEDM_00613 1.1e-54 ypaA S Protein of unknown function (DUF1304)
JHOFNEDM_00614 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
JHOFNEDM_00615 1.1e-231 flhF N Uncharacterized conserved protein (DUF2075)
JHOFNEDM_00616 1.6e-82 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
JHOFNEDM_00617 9.3e-80
JHOFNEDM_00618 1.4e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JHOFNEDM_00619 1e-173 rihC 3.2.2.1 F Nucleoside
JHOFNEDM_00620 3.3e-161 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
JHOFNEDM_00621 1.1e-77 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
JHOFNEDM_00622 1.8e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JHOFNEDM_00623 9.9e-180 proV E ABC transporter, ATP-binding protein
JHOFNEDM_00624 7.5e-255 gshR 1.8.1.7 C Glutathione reductase
JHOFNEDM_00625 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JHOFNEDM_00626 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
JHOFNEDM_00627 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
JHOFNEDM_00628 0.0 M domain protein
JHOFNEDM_00629 6.1e-31 M dTDP-4-dehydrorhamnose reductase activity
JHOFNEDM_00630 1.4e-175
JHOFNEDM_00631 6.5e-33
JHOFNEDM_00632 7e-38
JHOFNEDM_00633 9.6e-120 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
JHOFNEDM_00634 4.8e-197 uhpT EGP Major facilitator Superfamily
JHOFNEDM_00635 6.9e-147 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
JHOFNEDM_00636 3.3e-166 K Transcriptional regulator
JHOFNEDM_00637 1.4e-150 S hydrolase
JHOFNEDM_00638 1.6e-255 brnQ U Component of the transport system for branched-chain amino acids
JHOFNEDM_00639 2.1e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JHOFNEDM_00641 7.2e-32
JHOFNEDM_00642 2.9e-17 plnR
JHOFNEDM_00643 1.7e-117
JHOFNEDM_00644 5.2e-23 plnK
JHOFNEDM_00645 3.5e-24 plnJ
JHOFNEDM_00646 2.8e-28
JHOFNEDM_00648 1.4e-127 M Glycosyl transferase family 2
JHOFNEDM_00650 0.0 ybfG M peptidoglycan-binding domain-containing protein
JHOFNEDM_00651 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
JHOFNEDM_00652 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
JHOFNEDM_00653 1.9e-50 L Integrase
JHOFNEDM_00654 8.1e-91 L Reverse transcriptase (RNA-dependent DNA polymerase)
JHOFNEDM_00655 1.1e-54 S Bacterial mobilisation protein (MobC)
JHOFNEDM_00656 5.5e-185 U Relaxase/Mobilisation nuclease domain
JHOFNEDM_00657 9.6e-56 repA S Replication initiator protein A
JHOFNEDM_00658 1.3e-41
JHOFNEDM_00659 0.0 pacL 3.6.3.8 P P-type ATPase
JHOFNEDM_00660 1e-28
JHOFNEDM_00661 3.8e-51 K Helix-turn-helix XRE-family like proteins
JHOFNEDM_00662 7.4e-138 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JHOFNEDM_00663 4.3e-86 K PFAM helix-turn-helix- domain containing protein AraC type
JHOFNEDM_00664 1.9e-138 K Helix-turn-helix domain
JHOFNEDM_00665 7.1e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
JHOFNEDM_00666 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
JHOFNEDM_00667 3e-99 L Integrase
JHOFNEDM_00668 6.9e-62
JHOFNEDM_00669 4.6e-28
JHOFNEDM_00670 1.1e-84
JHOFNEDM_00671 6.2e-96 V VanZ like family
JHOFNEDM_00672 5e-195 blaA6 V Beta-lactamase
JHOFNEDM_00673 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
JHOFNEDM_00674 6.7e-161 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHOFNEDM_00675 5.1e-53 yitW S Pfam:DUF59
JHOFNEDM_00676 7.7e-174 S Aldo keto reductase
JHOFNEDM_00677 2.9e-30 FG HIT domain
JHOFNEDM_00678 5.6e-55 FG HIT domain
JHOFNEDM_00679 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
JHOFNEDM_00680 1.4e-77
JHOFNEDM_00681 6.2e-122 E GDSL-like Lipase/Acylhydrolase family
JHOFNEDM_00682 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
JHOFNEDM_00683 0.0 cadA P P-type ATPase
JHOFNEDM_00685 7.7e-123 yyaQ S YjbR
JHOFNEDM_00686 4.8e-221 S Uncharacterized protein conserved in bacteria (DUF2325)
JHOFNEDM_00687 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JHOFNEDM_00688 9.1e-181 frlB M SIS domain
JHOFNEDM_00689 3.5e-64
JHOFNEDM_00690 1.6e-75 yugI 5.3.1.9 J general stress protein
JHOFNEDM_00691 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JHOFNEDM_00692 3e-119 dedA S SNARE-like domain protein
JHOFNEDM_00693 4.6e-117 S Protein of unknown function (DUF1461)
JHOFNEDM_00694 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JHOFNEDM_00695 1.5e-80 yutD S Protein of unknown function (DUF1027)
JHOFNEDM_00696 8.7e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JHOFNEDM_00697 2.2e-116 S Calcineurin-like phosphoesterase
JHOFNEDM_00698 5.6e-253 cycA E Amino acid permease
JHOFNEDM_00699 1.6e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHOFNEDM_00700 3.6e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
JHOFNEDM_00702 4.5e-88 S Prokaryotic N-terminal methylation motif
JHOFNEDM_00703 8.6e-20
JHOFNEDM_00704 3.2e-83 gspG NU general secretion pathway protein
JHOFNEDM_00705 5.5e-43 comGC U competence protein ComGC
JHOFNEDM_00706 1.9e-189 comGB NU type II secretion system
JHOFNEDM_00707 2.4e-173 comGA NU Type II IV secretion system protein
JHOFNEDM_00708 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHOFNEDM_00709 8.3e-131 yebC K Transcriptional regulatory protein
JHOFNEDM_00710 2.3e-48 S DsrE/DsrF-like family
JHOFNEDM_00711 2.3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
JHOFNEDM_00712 1.9e-181 ccpA K catabolite control protein A
JHOFNEDM_00713 1.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
JHOFNEDM_00714 1.1e-80 K helix_turn_helix, mercury resistance
JHOFNEDM_00715 2.8e-56
JHOFNEDM_00716 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JHOFNEDM_00717 2.6e-158 ykuT M mechanosensitive ion channel
JHOFNEDM_00718 1.1e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JHOFNEDM_00719 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JHOFNEDM_00720 6.5e-87 ykuL S (CBS) domain
JHOFNEDM_00721 1.2e-94 S Phosphoesterase
JHOFNEDM_00722 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JHOFNEDM_00723 4.1e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JHOFNEDM_00724 9.9e-126 yslB S Protein of unknown function (DUF2507)
JHOFNEDM_00725 3.3e-52 trxA O Belongs to the thioredoxin family
JHOFNEDM_00726 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JHOFNEDM_00727 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JHOFNEDM_00728 1.6e-48 yrzB S Belongs to the UPF0473 family
JHOFNEDM_00729 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JHOFNEDM_00730 2.4e-43 yrzL S Belongs to the UPF0297 family
JHOFNEDM_00731 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JHOFNEDM_00732 7.1e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JHOFNEDM_00733 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
JHOFNEDM_00734 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JHOFNEDM_00735 6.3e-29 yajC U Preprotein translocase
JHOFNEDM_00736 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JHOFNEDM_00737 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JHOFNEDM_00738 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JHOFNEDM_00739 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JHOFNEDM_00740 2.7e-91
JHOFNEDM_00741 0.0 S Bacterial membrane protein YfhO
JHOFNEDM_00742 1.3e-72
JHOFNEDM_00743 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JHOFNEDM_00744 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JHOFNEDM_00745 2.7e-154 ymdB S YmdB-like protein
JHOFNEDM_00746 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
JHOFNEDM_00747 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JHOFNEDM_00748 7.2e-231 cinA 3.5.1.42 S Belongs to the CinA family
JHOFNEDM_00749 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JHOFNEDM_00750 5.7e-110 ymfM S Helix-turn-helix domain
JHOFNEDM_00751 2.9e-251 ymfH S Peptidase M16
JHOFNEDM_00752 6.5e-232 ymfF S Peptidase M16 inactive domain protein
JHOFNEDM_00753 1e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
JHOFNEDM_00754 1.5e-155 aatB ET ABC transporter substrate-binding protein
JHOFNEDM_00755 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JHOFNEDM_00756 4.6e-109 glnP P ABC transporter permease
JHOFNEDM_00757 1.2e-146 minD D Belongs to the ParA family
JHOFNEDM_00758 1.4e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
JHOFNEDM_00759 1.2e-88 mreD M rod shape-determining protein MreD
JHOFNEDM_00760 2.6e-144 mreC M Involved in formation and maintenance of cell shape
JHOFNEDM_00761 2.8e-161 mreB D cell shape determining protein MreB
JHOFNEDM_00762 1.3e-116 radC L DNA repair protein
JHOFNEDM_00763 4.7e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JHOFNEDM_00764 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JHOFNEDM_00765 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JHOFNEDM_00766 2e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
JHOFNEDM_00767 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHOFNEDM_00768 1.7e-218 iscS2 2.8.1.7 E Aminotransferase class V
JHOFNEDM_00769 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JHOFNEDM_00770 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
JHOFNEDM_00771 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JHOFNEDM_00772 5.2e-113 yktB S Belongs to the UPF0637 family
JHOFNEDM_00773 2.5e-80 yueI S Protein of unknown function (DUF1694)
JHOFNEDM_00774 7e-110 S Protein of unknown function (DUF1648)
JHOFNEDM_00775 5.6e-43 czrA K Helix-turn-helix domain
JHOFNEDM_00776 6.2e-230 malL 3.2.1.10 GH13 G COG0366 Glycosidases
JHOFNEDM_00777 9.2e-42 2.7.1.191 G PTS system fructose IIA component
JHOFNEDM_00778 2.7e-104 G PTS system mannose fructose sorbose family IID component
JHOFNEDM_00779 3.6e-103 G PTS system sorbose-specific iic component
JHOFNEDM_00780 6e-66 2.7.1.191 G PTS system sorbose subfamily IIB component
JHOFNEDM_00781 1.1e-93 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
JHOFNEDM_00782 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
JHOFNEDM_00783 8e-238 rarA L recombination factor protein RarA
JHOFNEDM_00784 1.5e-38
JHOFNEDM_00785 6.2e-82 usp6 T universal stress protein
JHOFNEDM_00786 1e-199 bla2 3.5.2.6 V Beta-lactamase enzyme family
JHOFNEDM_00787 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
JHOFNEDM_00788 5.1e-295 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
JHOFNEDM_00789 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JHOFNEDM_00790 6.8e-187 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
JHOFNEDM_00791 3.5e-177 S Protein of unknown function (DUF2785)
JHOFNEDM_00792 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
JHOFNEDM_00793 3.2e-147 metQ M Belongs to the nlpA lipoprotein family
JHOFNEDM_00794 1.4e-111 metI U ABC transporter permease
JHOFNEDM_00795 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JHOFNEDM_00796 3.6e-48 gcsH2 E glycine cleavage
JHOFNEDM_00797 9.3e-220 rodA D Belongs to the SEDS family
JHOFNEDM_00798 3.3e-33 S Protein of unknown function (DUF2969)
JHOFNEDM_00799 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
JHOFNEDM_00800 2.7e-180 mbl D Cell shape determining protein MreB Mrl
JHOFNEDM_00801 2.1e-102 J Acetyltransferase (GNAT) domain
JHOFNEDM_00802 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JHOFNEDM_00803 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JHOFNEDM_00804 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JHOFNEDM_00805 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JHOFNEDM_00806 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JHOFNEDM_00807 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JHOFNEDM_00808 1.6e-40 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JHOFNEDM_00809 1.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JHOFNEDM_00810 5.5e-103 atpB C it plays a direct role in the translocation of protons across the membrane
JHOFNEDM_00811 1e-232 pyrP F Permease
JHOFNEDM_00812 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JHOFNEDM_00813 3.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JHOFNEDM_00814 6.9e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JHOFNEDM_00815 1e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JHOFNEDM_00816 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JHOFNEDM_00817 9.3e-109 tdk 2.7.1.21 F thymidine kinase
JHOFNEDM_00818 1.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
JHOFNEDM_00819 5.9e-137 cobQ S glutamine amidotransferase
JHOFNEDM_00820 9.8e-196 manA 5.3.1.8 G mannose-6-phosphate isomerase
JHOFNEDM_00821 1.4e-192 ampC V Beta-lactamase
JHOFNEDM_00822 5.2e-29
JHOFNEDM_00823 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JHOFNEDM_00824 1.9e-58
JHOFNEDM_00825 5.3e-125
JHOFNEDM_00826 0.0 yfiC V ABC transporter
JHOFNEDM_00827 0.0 ycfI V ABC transporter, ATP-binding protein
JHOFNEDM_00828 4.3e-65 S Protein of unknown function (DUF1093)
JHOFNEDM_00829 3.8e-135 yxkH G Polysaccharide deacetylase
JHOFNEDM_00831 1.1e-28 hol S Bacteriophage holin
JHOFNEDM_00832 6.1e-48
JHOFNEDM_00833 4.8e-173 M Glycosyl hydrolases family 25
JHOFNEDM_00835 5.1e-70 S Protein of unknown function (DUF1617)
JHOFNEDM_00836 0.0 sidC GT2,GT4 LM DNA recombination
JHOFNEDM_00837 5.9e-61
JHOFNEDM_00838 0.0 D NLP P60 protein
JHOFNEDM_00839 8e-23
JHOFNEDM_00840 6.3e-64
JHOFNEDM_00841 6.9e-78 S Phage tail tube protein, TTP
JHOFNEDM_00842 1.4e-54
JHOFNEDM_00843 1e-88
JHOFNEDM_00844 1.5e-50
JHOFNEDM_00845 5.1e-51
JHOFNEDM_00847 2e-175 S Phage major capsid protein E
JHOFNEDM_00848 2.6e-50
JHOFNEDM_00849 2.7e-14 S Domain of unknown function (DUF4355)
JHOFNEDM_00851 2.4e-30
JHOFNEDM_00852 5.2e-301 S Phage Mu protein F like protein
JHOFNEDM_00853 3.3e-267 S Phage portal protein, SPP1 Gp6-like
JHOFNEDM_00854 4.1e-239 ps334 S Terminase-like family
JHOFNEDM_00855 4e-87 xtmA L Terminase small subunit
JHOFNEDM_00856 1.2e-26 S RloB-like protein
JHOFNEDM_00857 1.4e-146 S AAA domain, putative AbiEii toxin, Type IV TA system
JHOFNEDM_00860 1.1e-80 arpU S Phage transcriptional regulator, ArpU family
JHOFNEDM_00862 7.1e-65 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
JHOFNEDM_00863 2.4e-63
JHOFNEDM_00864 1.1e-63 ps308 K AntA/AntB antirepressor
JHOFNEDM_00865 1.2e-48
JHOFNEDM_00866 1.6e-152 3.1.3.16 L DnaD domain protein
JHOFNEDM_00867 1.3e-139 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
JHOFNEDM_00868 3.4e-150 recT L RecT family
JHOFNEDM_00869 1.1e-68
JHOFNEDM_00870 7.8e-08 S Domain of unknown function (DUF1508)
JHOFNEDM_00871 1.6e-75
JHOFNEDM_00872 2.9e-53
JHOFNEDM_00875 5.8e-26 K Cro/C1-type HTH DNA-binding domain
JHOFNEDM_00876 1.7e-37 K sequence-specific DNA binding
JHOFNEDM_00879 5.2e-18 K sequence-specific DNA binding
JHOFNEDM_00880 3.6e-09 S Pfam:Peptidase_M78
JHOFNEDM_00881 8.5e-11 S DNA/RNA non-specific endonuclease
JHOFNEDM_00884 3.5e-24 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JHOFNEDM_00885 3.2e-27
JHOFNEDM_00886 3.3e-35 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
JHOFNEDM_00891 3e-158 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
JHOFNEDM_00892 1.9e-83 S Protein of unknown function DUF262
JHOFNEDM_00893 1.8e-29
JHOFNEDM_00894 2.5e-219 int L Belongs to the 'phage' integrase family
JHOFNEDM_00896 8.9e-30
JHOFNEDM_00898 2e-38
JHOFNEDM_00899 1.4e-43
JHOFNEDM_00900 7.3e-83 K MarR family
JHOFNEDM_00901 0.0 bztC D nuclear chromosome segregation
JHOFNEDM_00902 7.9e-267 M MucBP domain
JHOFNEDM_00903 2.7e-16
JHOFNEDM_00904 7.2e-17
JHOFNEDM_00905 5.2e-15
JHOFNEDM_00906 1.1e-18
JHOFNEDM_00907 1.6e-16
JHOFNEDM_00908 1.6e-16
JHOFNEDM_00909 1.6e-16
JHOFNEDM_00910 1.9e-18
JHOFNEDM_00911 1.6e-16
JHOFNEDM_00912 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
JHOFNEDM_00913 2.9e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
JHOFNEDM_00914 0.0 macB3 V ABC transporter, ATP-binding protein
JHOFNEDM_00915 6.8e-24
JHOFNEDM_00916 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
JHOFNEDM_00917 9.7e-155 glcU U sugar transport
JHOFNEDM_00918 9.4e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
JHOFNEDM_00919 2.9e-287 yclK 2.7.13.3 T Histidine kinase
JHOFNEDM_00920 8.9e-133 K response regulator
JHOFNEDM_00921 3e-243 XK27_08635 S UPF0210 protein
JHOFNEDM_00922 8.9e-38 gcvR T Belongs to the UPF0237 family
JHOFNEDM_00923 2e-169 EG EamA-like transporter family
JHOFNEDM_00925 7.7e-92 S ECF-type riboflavin transporter, S component
JHOFNEDM_00926 8.6e-48
JHOFNEDM_00927 9.8e-214 yceI EGP Major facilitator Superfamily
JHOFNEDM_00928 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
JHOFNEDM_00929 3.8e-23
JHOFNEDM_00931 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
JHOFNEDM_00932 2.8e-173 ykfC 3.4.14.13 M NlpC/P60 family
JHOFNEDM_00933 6.6e-81 K AsnC family
JHOFNEDM_00934 2e-35
JHOFNEDM_00935 5.1e-34
JHOFNEDM_00936 7.8e-219 2.7.7.65 T diguanylate cyclase
JHOFNEDM_00937 7.8e-296 S ABC transporter, ATP-binding protein
JHOFNEDM_00938 2e-106 3.2.2.20 K acetyltransferase
JHOFNEDM_00939 5.8e-82 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JHOFNEDM_00940 2.7e-39
JHOFNEDM_00941 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
JHOFNEDM_00942 3.4e-188 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JHOFNEDM_00943 5e-162 degV S Uncharacterised protein, DegV family COG1307
JHOFNEDM_00944 7.3e-231 hom1 1.1.1.3 E Homoserine dehydrogenase
JHOFNEDM_00945 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
JHOFNEDM_00946 3.6e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
JHOFNEDM_00947 1.4e-176 XK27_08835 S ABC transporter
JHOFNEDM_00948 2.5e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
JHOFNEDM_00949 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
JHOFNEDM_00950 3.7e-257 npr 1.11.1.1 C NADH oxidase
JHOFNEDM_00951 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
JHOFNEDM_00952 4.8e-137 terC P membrane
JHOFNEDM_00953 2.4e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
JHOFNEDM_00954 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JHOFNEDM_00955 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
JHOFNEDM_00956 2.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JHOFNEDM_00957 3.8e-134 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JHOFNEDM_00958 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JHOFNEDM_00959 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JHOFNEDM_00960 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
JHOFNEDM_00961 1.2e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JHOFNEDM_00962 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JHOFNEDM_00963 1.3e-215 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JHOFNEDM_00964 1.7e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
JHOFNEDM_00965 1.8e-215 ysaA V RDD family
JHOFNEDM_00966 9.9e-166 corA P CorA-like Mg2+ transporter protein
JHOFNEDM_00967 2.1e-55 S Domain of unknown function (DU1801)
JHOFNEDM_00968 3.8e-90 rmeB K transcriptional regulator, MerR family
JHOFNEDM_00969 9.4e-147 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
JHOFNEDM_00970 8.6e-98 J glyoxalase III activity
JHOFNEDM_00971 8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JHOFNEDM_00972 1.1e-186 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
JHOFNEDM_00973 3.7e-34
JHOFNEDM_00974 9.2e-112 S Protein of unknown function (DUF1211)
JHOFNEDM_00975 0.0 ydgH S MMPL family
JHOFNEDM_00976 1.6e-288 M domain protein
JHOFNEDM_00977 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
JHOFNEDM_00978 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
JHOFNEDM_00979 0.0 glpQ 3.1.4.46 C phosphodiesterase
JHOFNEDM_00980 2.3e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JHOFNEDM_00981 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
JHOFNEDM_00982 4e-184 3.6.4.13 S domain, Protein
JHOFNEDM_00983 3.6e-168 S Polyphosphate kinase 2 (PPK2)
JHOFNEDM_00984 2.7e-97 drgA C Nitroreductase family
JHOFNEDM_00985 3.1e-178 iunH2 3.2.2.1 F nucleoside hydrolase
JHOFNEDM_00986 5.8e-150 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JHOFNEDM_00987 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
JHOFNEDM_00988 6.7e-157 ccpB 5.1.1.1 K lacI family
JHOFNEDM_00989 8.1e-117 K Helix-turn-helix domain, rpiR family
JHOFNEDM_00990 2.5e-175 S Oxidoreductase family, NAD-binding Rossmann fold
JHOFNEDM_00991 5.9e-199 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
JHOFNEDM_00992 0.0 yjcE P Sodium proton antiporter
JHOFNEDM_00993 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JHOFNEDM_00994 3.7e-107 pncA Q Isochorismatase family
JHOFNEDM_00995 2.7e-132
JHOFNEDM_00996 5.1e-125 skfE V ABC transporter
JHOFNEDM_00997 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
JHOFNEDM_00998 2.7e-45 S Enterocin A Immunity
JHOFNEDM_00999 5.3e-175 D Alpha beta
JHOFNEDM_01000 0.0 pepF2 E Oligopeptidase F
JHOFNEDM_01001 1.3e-72 K Transcriptional regulator
JHOFNEDM_01002 3e-164
JHOFNEDM_01003 1.3e-57
JHOFNEDM_01004 2.2e-47
JHOFNEDM_01005 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JHOFNEDM_01006 1.2e-67
JHOFNEDM_01007 3.2e-144 yjfP S Dienelactone hydrolase family
JHOFNEDM_01008 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
JHOFNEDM_01009 9.3e-206 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
JHOFNEDM_01010 5.2e-47
JHOFNEDM_01011 6.1e-43
JHOFNEDM_01012 5e-82 yybC S Protein of unknown function (DUF2798)
JHOFNEDM_01013 1.7e-73
JHOFNEDM_01014 4e-60
JHOFNEDM_01015 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
JHOFNEDM_01016 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
JHOFNEDM_01017 4.7e-79 uspA T universal stress protein
JHOFNEDM_01018 8.7e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JHOFNEDM_01019 5e-20
JHOFNEDM_01020 4.2e-44 S zinc-ribbon domain
JHOFNEDM_01021 3.7e-69 S response to antibiotic
JHOFNEDM_01022 1.7e-48 K Cro/C1-type HTH DNA-binding domain
JHOFNEDM_01023 5.6e-21 S Protein of unknown function (DUF2929)
JHOFNEDM_01024 9.4e-225 lsgC M Glycosyl transferases group 1
JHOFNEDM_01025 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
JHOFNEDM_01026 4.8e-162 S Putative esterase
JHOFNEDM_01027 2.4e-130 gntR2 K Transcriptional regulator
JHOFNEDM_01028 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JHOFNEDM_01029 5.8e-138
JHOFNEDM_01030 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
JHOFNEDM_01031 5.5e-138 rrp8 K LytTr DNA-binding domain
JHOFNEDM_01032 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
JHOFNEDM_01033 7.7e-61
JHOFNEDM_01034 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
JHOFNEDM_01035 4.4e-58
JHOFNEDM_01036 1.2e-239 yhdP S Transporter associated domain
JHOFNEDM_01037 4.9e-87 nrdI F Belongs to the NrdI family
JHOFNEDM_01038 2.9e-269 yjcE P Sodium proton antiporter
JHOFNEDM_01039 1.5e-211 yttB EGP Major facilitator Superfamily
JHOFNEDM_01040 2.5e-62 K helix_turn_helix, mercury resistance
JHOFNEDM_01041 1.8e-173 C Zinc-binding dehydrogenase
JHOFNEDM_01042 8.5e-57 S SdpI/YhfL protein family
JHOFNEDM_01043 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JHOFNEDM_01044 5.5e-261 gabR K Bacterial regulatory proteins, gntR family
JHOFNEDM_01045 1.4e-217 patA 2.6.1.1 E Aminotransferase
JHOFNEDM_01046 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JHOFNEDM_01047 3e-18
JHOFNEDM_01048 1.7e-126 S membrane transporter protein
JHOFNEDM_01049 1.9e-161 mleR K LysR family
JHOFNEDM_01050 5.6e-115 ylbE GM NAD(P)H-binding
JHOFNEDM_01051 8.2e-96 wecD K Acetyltransferase (GNAT) family
JHOFNEDM_01052 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JHOFNEDM_01053 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
JHOFNEDM_01054 4.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
JHOFNEDM_01055 1.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JHOFNEDM_01056 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JHOFNEDM_01057 9.7e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JHOFNEDM_01058 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
JHOFNEDM_01059 1.5e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JHOFNEDM_01060 1.5e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JHOFNEDM_01061 1.2e-171 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JHOFNEDM_01062 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JHOFNEDM_01063 3.9e-298 pucR QT Purine catabolism regulatory protein-like family
JHOFNEDM_01064 3.5e-236 pbuX F xanthine permease
JHOFNEDM_01065 2.4e-221 pbuG S Permease family
JHOFNEDM_01066 3.9e-162 GM NmrA-like family
JHOFNEDM_01067 6.5e-156 T EAL domain
JHOFNEDM_01068 1.3e-93
JHOFNEDM_01069 9.2e-253 pgaC GT2 M Glycosyl transferase
JHOFNEDM_01070 4.5e-123 2.1.1.14 E Methionine synthase
JHOFNEDM_01071 3.2e-215 purD 6.3.4.13 F Belongs to the GARS family
JHOFNEDM_01072 7.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JHOFNEDM_01073 2.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JHOFNEDM_01074 9.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JHOFNEDM_01075 1.1e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JHOFNEDM_01076 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JHOFNEDM_01077 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JHOFNEDM_01078 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JHOFNEDM_01079 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JHOFNEDM_01080 1.9e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JHOFNEDM_01081 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JHOFNEDM_01082 1.5e-223 XK27_09615 1.3.5.4 S reductase
JHOFNEDM_01083 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
JHOFNEDM_01084 1.4e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
JHOFNEDM_01085 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
JHOFNEDM_01086 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
JHOFNEDM_01087 1.1e-147 S Alpha/beta hydrolase of unknown function (DUF915)
JHOFNEDM_01088 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
JHOFNEDM_01089 2.3e-139 cysA V ABC transporter, ATP-binding protein
JHOFNEDM_01090 0.0 V FtsX-like permease family
JHOFNEDM_01091 8e-42
JHOFNEDM_01092 7.9e-61 gntR1 K Transcriptional regulator, GntR family
JHOFNEDM_01093 6.9e-164 V ABC transporter, ATP-binding protein
JHOFNEDM_01094 2.9e-148
JHOFNEDM_01095 6.7e-81 uspA T universal stress protein
JHOFNEDM_01096 1.2e-35
JHOFNEDM_01097 4.2e-71 gtcA S Teichoic acid glycosylation protein
JHOFNEDM_01098 2.5e-88
JHOFNEDM_01099 1e-48
JHOFNEDM_01101 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
JHOFNEDM_01102 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
JHOFNEDM_01103 5.4e-118
JHOFNEDM_01104 1.5e-52
JHOFNEDM_01106 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
JHOFNEDM_01107 1.5e-280 thrC 4.2.3.1 E Threonine synthase
JHOFNEDM_01108 8.5e-145 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
JHOFNEDM_01109 9.8e-11 mcbG S Pentapeptide repeats (8 copies)
JHOFNEDM_01110 1.7e-111 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
JHOFNEDM_01111 3.1e-101 3.6.1.13 L Belongs to the Nudix hydrolase family
JHOFNEDM_01112 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
JHOFNEDM_01113 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
JHOFNEDM_01114 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
JHOFNEDM_01115 3.8e-212 S Bacterial protein of unknown function (DUF871)
JHOFNEDM_01116 2.1e-232 S Sterol carrier protein domain
JHOFNEDM_01117 3.6e-88 niaR S 3H domain
JHOFNEDM_01118 8.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JHOFNEDM_01119 1.3e-117 K Transcriptional regulator
JHOFNEDM_01120 3.2e-154 V ABC transporter
JHOFNEDM_01121 2.4e-133 V AAA domain, putative AbiEii toxin, Type IV TA system
JHOFNEDM_01122 1.1e-245 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
JHOFNEDM_01123 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHOFNEDM_01124 9.5e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHOFNEDM_01125 5.1e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
JHOFNEDM_01126 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
JHOFNEDM_01127 1.8e-130 gntR K UTRA
JHOFNEDM_01128 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
JHOFNEDM_01129 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
JHOFNEDM_01130 1.8e-81
JHOFNEDM_01131 9.8e-152 S hydrolase
JHOFNEDM_01132 6.5e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JHOFNEDM_01133 4.1e-151 EG EamA-like transporter family
JHOFNEDM_01134 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
JHOFNEDM_01135 1.2e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
JHOFNEDM_01136 4.1e-234
JHOFNEDM_01137 1.1e-77 fld C Flavodoxin
JHOFNEDM_01138 0.0 M Bacterial Ig-like domain (group 3)
JHOFNEDM_01139 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
JHOFNEDM_01140 2.7e-32
JHOFNEDM_01141 6.1e-129 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
JHOFNEDM_01142 7.6e-269 ycaM E amino acid
JHOFNEDM_01143 7.9e-79 K Winged helix DNA-binding domain
JHOFNEDM_01144 3.3e-166 S Oxidoreductase, aldo keto reductase family protein
JHOFNEDM_01145 5.7e-163 akr5f 1.1.1.346 S reductase
JHOFNEDM_01146 4.6e-163 K Transcriptional regulator
JHOFNEDM_01148 2e-61 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
JHOFNEDM_01150 4.7e-81 nrdI F NrdI Flavodoxin like
JHOFNEDM_01151 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHOFNEDM_01152 8.9e-170 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
JHOFNEDM_01153 2.3e-181 1.17.4.1 F Ribonucleotide reductase, small chain
JHOFNEDM_01154 1.6e-38 L hmm pf00665
JHOFNEDM_01155 9.5e-107 L Resolvase, N terminal domain
JHOFNEDM_01156 2.1e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHOFNEDM_01157 1.6e-75 L Putative transposase of IS4/5 family (DUF4096)
JHOFNEDM_01158 1.6e-60 L Transposase DDE domain
JHOFNEDM_01159 1.1e-193 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JHOFNEDM_01160 6.5e-290 clcA P chloride
JHOFNEDM_01161 7.8e-59 K Transcriptional regulator, LysR family
JHOFNEDM_01162 1.8e-107 E Peptidase family M20/M25/M40
JHOFNEDM_01163 1.7e-155 G Major Facilitator Superfamily
JHOFNEDM_01164 1.6e-162 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
JHOFNEDM_01165 1.7e-91 L Integrase core domain
JHOFNEDM_01166 7.6e-191 L Transposase and inactivated derivatives, IS30 family
JHOFNEDM_01167 1e-247 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
JHOFNEDM_01168 2.1e-133 scrK 2.7.1.2, 2.7.1.4 GK ROK family
JHOFNEDM_01169 8.4e-34 4.4.1.5 E Glyoxalase-like domain
JHOFNEDM_01170 5.6e-53 yraE S haloacid dehalogenase-like hydrolase
JHOFNEDM_01171 1.2e-149 3.2.1.26 GH32 G Glycosyl hydrolases family 32 N-terminal domain
JHOFNEDM_01172 5.8e-101 G Phosphotransferase system, EIIC
JHOFNEDM_01173 2.8e-27 G PTS system, Lactose/Cellobiose specific IIB subunit
JHOFNEDM_01174 7.4e-32 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JHOFNEDM_01175 9.8e-110 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JHOFNEDM_01176 1.5e-191 L Transposase and inactivated derivatives, IS30 family
JHOFNEDM_01177 4.3e-224 Z012_07420 3.1.21.5 V Z1 domain
JHOFNEDM_01178 7.8e-105 L NgoFVII restriction endonuclease
JHOFNEDM_01179 3.6e-189 2.1.1.37 H C-5 cytosine-specific DNA methylase
JHOFNEDM_01180 1.4e-111 S VIT family
JHOFNEDM_01181 1.8e-119 S membrane
JHOFNEDM_01182 1.6e-158 EG EamA-like transporter family
JHOFNEDM_01183 1.3e-81 elaA S GNAT family
JHOFNEDM_01184 7.3e-115 GM NmrA-like family
JHOFNEDM_01185 2.1e-14
JHOFNEDM_01186 2.6e-55
JHOFNEDM_01187 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
JHOFNEDM_01188 1.3e-85
JHOFNEDM_01189 1.9e-62
JHOFNEDM_01190 5.3e-214 mutY L A G-specific adenine glycosylase
JHOFNEDM_01191 4e-53
JHOFNEDM_01192 6.3e-66 yeaO S Protein of unknown function, DUF488
JHOFNEDM_01193 7e-71 spx4 1.20.4.1 P ArsC family
JHOFNEDM_01194 2.1e-65 K Winged helix DNA-binding domain
JHOFNEDM_01195 4.1e-161 azoB GM NmrA-like family
JHOFNEDM_01196 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
JHOFNEDM_01197 1.8e-167 S Alpha/beta hydrolase of unknown function (DUF915)
JHOFNEDM_01198 2.6e-250 cycA E Amino acid permease
JHOFNEDM_01199 4.7e-255 nhaC C Na H antiporter NhaC
JHOFNEDM_01200 6.1e-27 3.2.2.10 S Belongs to the LOG family
JHOFNEDM_01201 9.1e-192 L Transposase and inactivated derivatives, IS30 family
JHOFNEDM_01203 4.9e-159 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JHOFNEDM_01204 4e-29 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
JHOFNEDM_01205 3.1e-11 relB L bacterial-type proximal promoter sequence-specific DNA binding
JHOFNEDM_01206 4.5e-94 cps2I S Psort location CytoplasmicMembrane, score
JHOFNEDM_01207 2.8e-31 cpsJ S Glycosyltransferase like family 2
JHOFNEDM_01208 9.8e-86 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
JHOFNEDM_01209 1.1e-38 wzy S EpsG family
JHOFNEDM_01210 7.7e-17 M Glycosyltransferase, group 1 family protein
JHOFNEDM_01211 5.2e-08 GT4 M Glycosyl transferases group 1
JHOFNEDM_01212 2.9e-38 L Transposase and inactivated derivatives
JHOFNEDM_01213 2.6e-60 M Glycosyltransferase sugar-binding region containing DXD motif
JHOFNEDM_01214 3.5e-47 tuaG GT2 M Glycosyltransferase like family 2
JHOFNEDM_01215 2.9e-122 tuaA M Bacterial sugar transferase
JHOFNEDM_01216 9.7e-172 cps2D 5.1.3.2 M RmlD substrate binding domain
JHOFNEDM_01217 3e-139 ywqE 3.1.3.48 GM PHP domain protein
JHOFNEDM_01218 1.6e-126 ywqD 2.7.10.1 D Capsular exopolysaccharide family
JHOFNEDM_01219 2.2e-121 epsB M biosynthesis protein
JHOFNEDM_01220 4.9e-39
JHOFNEDM_01221 4.7e-26
JHOFNEDM_01222 0.0 L MobA MobL family protein
JHOFNEDM_01223 7.6e-49
JHOFNEDM_01224 1.2e-106
JHOFNEDM_01225 1.3e-51 S Cag pathogenicity island, type IV secretory system
JHOFNEDM_01226 7.8e-37
JHOFNEDM_01227 5.2e-116
JHOFNEDM_01228 0.0 U AAA-like domain
JHOFNEDM_01229 6.2e-231 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
JHOFNEDM_01230 7.6e-211 M CHAP domain
JHOFNEDM_01231 3.7e-87
JHOFNEDM_01232 2.4e-62 CO COG0526, thiol-disulfide isomerase and thioredoxins
JHOFNEDM_01233 2.1e-79
JHOFNEDM_01234 2.2e-261 traK U TraM recognition site of TraD and TraG
JHOFNEDM_01235 4e-63
JHOFNEDM_01236 1.7e-151
JHOFNEDM_01237 2.5e-68
JHOFNEDM_01238 3.9e-219 yfjM S Protein of unknown function DUF262
JHOFNEDM_01239 2.8e-61
JHOFNEDM_01240 4.4e-52
JHOFNEDM_01241 1e-248 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
JHOFNEDM_01242 1e-06 S FRG domain
JHOFNEDM_01243 5.7e-93 S SIR2-like domain
JHOFNEDM_01244 1.7e-209 S Domain of unknown function DUF87
JHOFNEDM_01246 4.4e-188 L PFAM Integrase catalytic region
JHOFNEDM_01247 8.5e-75 L Transposase DDE domain
JHOFNEDM_01248 1.1e-65 L Putative transposase of IS4/5 family (DUF4096)
JHOFNEDM_01249 0.0 kup P Transport of potassium into the cell
JHOFNEDM_01250 5e-64 KT Transcriptional regulatory protein, C terminal
JHOFNEDM_01251 3.8e-181 T PhoQ Sensor
JHOFNEDM_01252 2.3e-38 kdpC 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JHOFNEDM_01253 1.5e-254 kdpB 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JHOFNEDM_01254 2.5e-173 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JHOFNEDM_01257 3.6e-235 L Transposase
JHOFNEDM_01258 2.4e-19
JHOFNEDM_01259 0.0 O Belongs to the peptidase S8 family
JHOFNEDM_01261 3.4e-18 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JHOFNEDM_01262 1.6e-127 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
JHOFNEDM_01263 9.9e-183 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
JHOFNEDM_01264 2.1e-109 D This gene contains a nucleotide ambiguity which may be the result of a sequencing error
JHOFNEDM_01265 2.2e-75 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
JHOFNEDM_01266 1.1e-36 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
JHOFNEDM_01267 1.4e-183 ycsG P Natural resistance-associated macrophage protein
JHOFNEDM_01268 8.9e-112 ycsF S LamB/YcsF family
JHOFNEDM_01269 4.5e-130 ycsI S Protein of unknown function (DUF1445)
JHOFNEDM_01270 1.1e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
JHOFNEDM_01271 3.4e-36 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JHOFNEDM_01272 3e-91 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
JHOFNEDM_01273 8.3e-76 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
JHOFNEDM_01274 4e-19 K helix_turn_helix multiple antibiotic resistance protein
JHOFNEDM_01275 2.5e-152
JHOFNEDM_01276 5.3e-35 S Cell surface protein
JHOFNEDM_01279 2.1e-08 L Helix-turn-helix domain
JHOFNEDM_01280 1.8e-12 L Helix-turn-helix domain
JHOFNEDM_01281 5.9e-17 K helix_turn_helix multiple antibiotic resistance protein
JHOFNEDM_01282 7.5e-19 M Bacterial Ig-like domain (group 3)
JHOFNEDM_01283 4.3e-09 3.4.21.72 M Bacterial Ig-like domain (group 3)
JHOFNEDM_01285 6.7e-48 K sequence-specific DNA binding
JHOFNEDM_01286 9.2e-181 L PFAM Integrase, catalytic core
JHOFNEDM_01287 2e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
JHOFNEDM_01288 2.7e-163 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
JHOFNEDM_01289 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
JHOFNEDM_01290 7.4e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
JHOFNEDM_01291 7.9e-208 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
JHOFNEDM_01292 2.9e-179 citR K sugar-binding domain protein
JHOFNEDM_01293 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
JHOFNEDM_01294 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JHOFNEDM_01295 3.1e-50
JHOFNEDM_01296 3.5e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
JHOFNEDM_01297 4.8e-141 mtsB U ABC 3 transport family
JHOFNEDM_01298 4.5e-132 mntB 3.6.3.35 P ABC transporter
JHOFNEDM_01299 3.6e-154 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
JHOFNEDM_01300 1.2e-199 K Helix-turn-helix domain
JHOFNEDM_01301 4.4e-177 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
JHOFNEDM_01302 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
JHOFNEDM_01303 4.1e-53 yitW S Iron-sulfur cluster assembly protein
JHOFNEDM_01304 1.2e-263 P Sodium:sulfate symporter transmembrane region
JHOFNEDM_01305 4.9e-196 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JHOFNEDM_01306 4e-184 aroF 2.5.1.54 E DAHP synthetase I family
JHOFNEDM_01307 1.2e-163 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JHOFNEDM_01308 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JHOFNEDM_01309 2.5e-203 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
JHOFNEDM_01310 1.7e-183 ywhK S Membrane
JHOFNEDM_01311 2.3e-164 degV S Uncharacterised protein, DegV family COG1307
JHOFNEDM_01312 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
JHOFNEDM_01313 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JHOFNEDM_01314 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JHOFNEDM_01315 5e-145 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JHOFNEDM_01316 2.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JHOFNEDM_01317 4.7e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JHOFNEDM_01318 1.5e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JHOFNEDM_01319 3.5e-142 cad S FMN_bind
JHOFNEDM_01320 0.0 ndh 1.6.99.3 C NADH dehydrogenase
JHOFNEDM_01321 1.4e-86 ynhH S NusG domain II
JHOFNEDM_01322 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
JHOFNEDM_01323 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JHOFNEDM_01324 2.1e-61 rplQ J Ribosomal protein L17
JHOFNEDM_01325 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JHOFNEDM_01326 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JHOFNEDM_01327 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JHOFNEDM_01328 3.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JHOFNEDM_01329 6.2e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JHOFNEDM_01330 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JHOFNEDM_01331 6.3e-70 rplO J Binds to the 23S rRNA
JHOFNEDM_01332 2.2e-24 rpmD J Ribosomal protein L30
JHOFNEDM_01333 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JHOFNEDM_01334 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JHOFNEDM_01335 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JHOFNEDM_01336 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JHOFNEDM_01337 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JHOFNEDM_01338 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JHOFNEDM_01339 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JHOFNEDM_01340 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JHOFNEDM_01341 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
JHOFNEDM_01342 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JHOFNEDM_01343 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JHOFNEDM_01344 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JHOFNEDM_01345 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JHOFNEDM_01346 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JHOFNEDM_01347 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JHOFNEDM_01348 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
JHOFNEDM_01349 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JHOFNEDM_01350 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
JHOFNEDM_01351 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JHOFNEDM_01352 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JHOFNEDM_01353 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JHOFNEDM_01354 6.6e-114 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
JHOFNEDM_01355 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JHOFNEDM_01356 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JHOFNEDM_01357 1.5e-109 K Bacterial regulatory proteins, tetR family
JHOFNEDM_01358 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
JHOFNEDM_01359 6.9e-78 ctsR K Belongs to the CtsR family
JHOFNEDM_01367 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JHOFNEDM_01368 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
JHOFNEDM_01369 2.5e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
JHOFNEDM_01370 1.5e-264 lysP E amino acid
JHOFNEDM_01371 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JHOFNEDM_01372 4.2e-92 K Transcriptional regulator
JHOFNEDM_01373 8.2e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
JHOFNEDM_01374 2e-154 I alpha/beta hydrolase fold
JHOFNEDM_01375 2.3e-119 lssY 3.6.1.27 I phosphatase
JHOFNEDM_01376 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
JHOFNEDM_01377 2.2e-76 S Threonine/Serine exporter, ThrE
JHOFNEDM_01378 7.2e-130 thrE S Putative threonine/serine exporter
JHOFNEDM_01379 6e-31 cspC K Cold shock protein
JHOFNEDM_01380 2e-120 sirR K iron dependent repressor
JHOFNEDM_01381 2.6e-58
JHOFNEDM_01382 1.7e-84 merR K MerR HTH family regulatory protein
JHOFNEDM_01383 7e-270 lmrB EGP Major facilitator Superfamily
JHOFNEDM_01384 1.4e-117 S Domain of unknown function (DUF4811)
JHOFNEDM_01385 1e-106
JHOFNEDM_01386 4.4e-35 yyaN K MerR HTH family regulatory protein
JHOFNEDM_01387 1.1e-119 azlC E branched-chain amino acid
JHOFNEDM_01388 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
JHOFNEDM_01389 0.0 asnB 6.3.5.4 E Asparagine synthase
JHOFNEDM_01390 3.5e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
JHOFNEDM_01391 6.8e-281 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JHOFNEDM_01392 6.1e-255 xylP2 G symporter
JHOFNEDM_01393 2.6e-191 nlhH_1 I alpha/beta hydrolase fold
JHOFNEDM_01394 5.6e-49
JHOFNEDM_01395 5e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
JHOFNEDM_01396 2.4e-101 3.2.2.20 K FR47-like protein
JHOFNEDM_01397 1.3e-126 yibF S overlaps another CDS with the same product name
JHOFNEDM_01398 1.4e-218 yibE S overlaps another CDS with the same product name
JHOFNEDM_01399 2.3e-179
JHOFNEDM_01400 5.6e-138 S NADPH-dependent FMN reductase
JHOFNEDM_01401 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
JHOFNEDM_01402 1.4e-161 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
JHOFNEDM_01403 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
JHOFNEDM_01404 4.1e-32 L leucine-zipper of insertion element IS481
JHOFNEDM_01405 1e-41
JHOFNEDM_01406 3.9e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JHOFNEDM_01407 6.7e-278 pipD E Dipeptidase
JHOFNEDM_01408 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
JHOFNEDM_01409 2.8e-254 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
JHOFNEDM_01410 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JHOFNEDM_01411 2.3e-81 rmaD K Transcriptional regulator
JHOFNEDM_01413 0.0 1.3.5.4 C FMN_bind
JHOFNEDM_01414 9.5e-172 K Transcriptional regulator
JHOFNEDM_01415 7.8e-97 K Helix-turn-helix domain
JHOFNEDM_01416 2.9e-139 K sequence-specific DNA binding
JHOFNEDM_01417 8e-73 S AAA domain
JHOFNEDM_01419 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
JHOFNEDM_01420 3e-90 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
JHOFNEDM_01421 2.6e-44 S MazG-like family
JHOFNEDM_01422 0.0 N Uncharacterized conserved protein (DUF2075)
JHOFNEDM_01423 0.0 pepN 3.4.11.2 E aminopeptidase
JHOFNEDM_01424 4.1e-101 G Glycogen debranching enzyme
JHOFNEDM_01425 3.4e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
JHOFNEDM_01426 1e-155 yjdB S Domain of unknown function (DUF4767)
JHOFNEDM_01427 7e-147 Q Fumarylacetoacetate (FAA) hydrolase family
JHOFNEDM_01428 5.3e-72 asp2 S Asp23 family, cell envelope-related function
JHOFNEDM_01429 8.7e-72 asp S Asp23 family, cell envelope-related function
JHOFNEDM_01430 7.2e-23
JHOFNEDM_01431 2.6e-84
JHOFNEDM_01432 7.1e-37 S Transglycosylase associated protein
JHOFNEDM_01433 0.0 XK27_09800 I Acyltransferase family
JHOFNEDM_01434 7.4e-38 S MORN repeat
JHOFNEDM_01435 6.7e-164 S Cysteine-rich secretory protein family
JHOFNEDM_01436 7.1e-234 EGP Major facilitator Superfamily
JHOFNEDM_01437 4.2e-56 hxlR K HxlR-like helix-turn-helix
JHOFNEDM_01438 2e-110 XK27_07075 V CAAX protease self-immunity
JHOFNEDM_01439 1.7e-63 K Helix-turn-helix XRE-family like proteins
JHOFNEDM_01440 6.2e-50
JHOFNEDM_01441 1.1e-78
JHOFNEDM_01442 8.9e-23 L hmm pf00665
JHOFNEDM_01443 6.9e-29 L hmm pf00665
JHOFNEDM_01444 2e-18 L hmm pf00665
JHOFNEDM_01445 7.6e-46 L Helix-turn-helix domain
JHOFNEDM_01447 5.1e-143 spoVK O ATPase family associated with various cellular activities (AAA)
JHOFNEDM_01449 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JHOFNEDM_01450 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
JHOFNEDM_01451 1.7e-165 fabK 1.3.1.9 S Nitronate monooxygenase
JHOFNEDM_01452 0.0 helD 3.6.4.12 L DNA helicase
JHOFNEDM_01453 7.7e-112 dedA S SNARE associated Golgi protein
JHOFNEDM_01454 7e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
JHOFNEDM_01455 0.0 yjbQ P TrkA C-terminal domain protein
JHOFNEDM_01456 4.7e-125 pgm3 G Phosphoglycerate mutase family
JHOFNEDM_01457 5.5e-129 pgm3 G Phosphoglycerate mutase family
JHOFNEDM_01458 1.2e-26
JHOFNEDM_01459 1.3e-48 sugE U Multidrug resistance protein
JHOFNEDM_01460 6.4e-78 3.6.1.55 F NUDIX domain
JHOFNEDM_01461 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JHOFNEDM_01462 4.6e-97 K Bacterial regulatory proteins, tetR family
JHOFNEDM_01463 3.8e-85 S membrane transporter protein
JHOFNEDM_01464 8.3e-210 EGP Major facilitator Superfamily
JHOFNEDM_01465 2e-71 K MarR family
JHOFNEDM_01466 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
JHOFNEDM_01467 4.8e-73 mgrA K helix_turn_helix multiple antibiotic resistance protein
JHOFNEDM_01468 2.4e-245 steT E amino acid
JHOFNEDM_01469 4.6e-140 G YdjC-like protein
JHOFNEDM_01470 3.9e-257 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
JHOFNEDM_01471 4.7e-154 K CAT RNA binding domain
JHOFNEDM_01472 2.6e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
JHOFNEDM_01473 4e-108 glnP P ABC transporter permease
JHOFNEDM_01474 1.3e-108 gluC P ABC transporter permease
JHOFNEDM_01475 7.8e-149 glnH ET ABC transporter substrate-binding protein
JHOFNEDM_01476 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JHOFNEDM_01477 3.6e-41
JHOFNEDM_01478 3.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHOFNEDM_01479 1.1e-209 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
JHOFNEDM_01480 2e-112 gph 3.1.3.18 S HAD hydrolase, family IA, variant
JHOFNEDM_01481 4.9e-148
JHOFNEDM_01482 7.1e-12 3.2.1.14 GH18
JHOFNEDM_01483 1.3e-81 zur P Belongs to the Fur family
JHOFNEDM_01484 6.3e-105 gmk2 2.7.4.8 F Guanylate kinase
JHOFNEDM_01485 1.8e-19
JHOFNEDM_01486 1.7e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
JHOFNEDM_01487 9.9e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
JHOFNEDM_01488 2.5e-88
JHOFNEDM_01489 8.2e-252 yfnA E Amino Acid
JHOFNEDM_01490 5.8e-46
JHOFNEDM_01491 5e-69 O OsmC-like protein
JHOFNEDM_01492 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
JHOFNEDM_01493 0.0 oatA I Acyltransferase
JHOFNEDM_01494 2e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JHOFNEDM_01495 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
JHOFNEDM_01496 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JHOFNEDM_01497 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JHOFNEDM_01498 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JHOFNEDM_01499 1.2e-225 pbuG S permease
JHOFNEDM_01500 1.5e-19
JHOFNEDM_01501 1.3e-82 K Transcriptional regulator
JHOFNEDM_01502 5e-153 licD M LicD family
JHOFNEDM_01503 1.8e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
JHOFNEDM_01504 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JHOFNEDM_01505 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
JHOFNEDM_01506 6.7e-241 EGP Major facilitator Superfamily
JHOFNEDM_01507 1.1e-89 V VanZ like family
JHOFNEDM_01508 2.5e-33
JHOFNEDM_01509 1.9e-71 spxA 1.20.4.1 P ArsC family
JHOFNEDM_01511 2.5e-141
JHOFNEDM_01512 2.8e-298 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JHOFNEDM_01513 1.2e-33 G Transmembrane secretion effector
JHOFNEDM_01514 9.2e-139 EGP Transmembrane secretion effector
JHOFNEDM_01515 3e-131 1.5.1.39 C nitroreductase
JHOFNEDM_01516 3e-72
JHOFNEDM_01517 1.5e-52
JHOFNEDM_01518 1.3e-206 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JHOFNEDM_01519 7e-104 K Bacterial regulatory proteins, tetR family
JHOFNEDM_01520 6.4e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
JHOFNEDM_01521 1.3e-122 yliE T EAL domain
JHOFNEDM_01522 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JHOFNEDM_01523 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHOFNEDM_01524 1.6e-129 ybbR S YbbR-like protein
JHOFNEDM_01525 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JHOFNEDM_01526 1.8e-119 S Protein of unknown function (DUF1361)
JHOFNEDM_01527 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
JHOFNEDM_01528 0.0 yjcE P Sodium proton antiporter
JHOFNEDM_01529 1.4e-167 murB 1.3.1.98 M Cell wall formation
JHOFNEDM_01530 3.9e-162 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
JHOFNEDM_01531 2.8e-153 xth 3.1.11.2 L exodeoxyribonuclease III
JHOFNEDM_01532 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
JHOFNEDM_01533 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
JHOFNEDM_01534 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
JHOFNEDM_01535 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
JHOFNEDM_01536 6.3e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JHOFNEDM_01537 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
JHOFNEDM_01538 6.1e-105 yxjI
JHOFNEDM_01539 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JHOFNEDM_01540 1.5e-256 glnP P ABC transporter
JHOFNEDM_01541 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
JHOFNEDM_01542 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
JHOFNEDM_01543 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JHOFNEDM_01544 1.3e-139 est 3.1.1.1 S Serine aminopeptidase, S33
JHOFNEDM_01545 1.2e-30 secG U Preprotein translocase
JHOFNEDM_01546 6.6e-295 clcA P chloride
JHOFNEDM_01547 1.3e-133
JHOFNEDM_01548 6.2e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JHOFNEDM_01549 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JHOFNEDM_01550 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JHOFNEDM_01551 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JHOFNEDM_01552 7.3e-189 cggR K Putative sugar-binding domain
JHOFNEDM_01553 4.2e-245 rpoN K Sigma-54 factor, core binding domain
JHOFNEDM_01555 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JHOFNEDM_01556 3.9e-176 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHOFNEDM_01557 2.6e-305 oppA E ABC transporter, substratebinding protein
JHOFNEDM_01558 3.7e-168 whiA K May be required for sporulation
JHOFNEDM_01559 2.9e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JHOFNEDM_01560 1.1e-161 rapZ S Displays ATPase and GTPase activities
JHOFNEDM_01561 9.3e-87 S Short repeat of unknown function (DUF308)
JHOFNEDM_01562 7.2e-264 argH 4.3.2.1 E argininosuccinate lyase
JHOFNEDM_01563 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JHOFNEDM_01564 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JHOFNEDM_01565 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
JHOFNEDM_01566 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JHOFNEDM_01567 1.2e-117 yfbR S HD containing hydrolase-like enzyme
JHOFNEDM_01568 9.2e-212 norA EGP Major facilitator Superfamily
JHOFNEDM_01569 1.1e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
JHOFNEDM_01570 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
JHOFNEDM_01571 3.3e-132 yliE T Putative diguanylate phosphodiesterase
JHOFNEDM_01572 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
JHOFNEDM_01573 1.1e-61 S Protein of unknown function (DUF3290)
JHOFNEDM_01574 2e-109 yviA S Protein of unknown function (DUF421)
JHOFNEDM_01575 8.4e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JHOFNEDM_01576 1e-132 2.7.7.65 T diguanylate cyclase activity
JHOFNEDM_01577 0.0 ydaN S Bacterial cellulose synthase subunit
JHOFNEDM_01578 6.8e-218 ydaM M Glycosyl transferase family group 2
JHOFNEDM_01579 2.5e-204 S Protein conserved in bacteria
JHOFNEDM_01580 3.6e-245
JHOFNEDM_01581 4.3e-163 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
JHOFNEDM_01582 6.7e-270 nox C NADH oxidase
JHOFNEDM_01583 1.9e-124 yliE T Putative diguanylate phosphodiesterase
JHOFNEDM_01584 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JHOFNEDM_01585 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JHOFNEDM_01586 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JHOFNEDM_01587 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JHOFNEDM_01588 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
JHOFNEDM_01589 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
JHOFNEDM_01590 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
JHOFNEDM_01591 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JHOFNEDM_01592 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JHOFNEDM_01593 1.5e-155 pstA P Phosphate transport system permease protein PstA
JHOFNEDM_01594 1.5e-161 pstC P probably responsible for the translocation of the substrate across the membrane
JHOFNEDM_01595 6.7e-151 pstS P Phosphate
JHOFNEDM_01596 9.2e-251 phoR 2.7.13.3 T Histidine kinase
JHOFNEDM_01597 1.5e-132 K response regulator
JHOFNEDM_01598 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
JHOFNEDM_01599 3.2e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JHOFNEDM_01600 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JHOFNEDM_01601 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JHOFNEDM_01602 4.8e-125 comFC S Competence protein
JHOFNEDM_01603 3.7e-257 comFA L Helicase C-terminal domain protein
JHOFNEDM_01604 6.3e-114 yvyE 3.4.13.9 S YigZ family
JHOFNEDM_01605 2.8e-144 pstS P Phosphate
JHOFNEDM_01606 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
JHOFNEDM_01607 0.0 ydaO E amino acid
JHOFNEDM_01608 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JHOFNEDM_01609 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JHOFNEDM_01610 6.1e-109 ydiL S CAAX protease self-immunity
JHOFNEDM_01611 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JHOFNEDM_01612 7.4e-307 uup S ABC transporter, ATP-binding protein
JHOFNEDM_01613 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JHOFNEDM_01614 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JHOFNEDM_01615 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
JHOFNEDM_01616 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
JHOFNEDM_01617 8.2e-188 phnD P Phosphonate ABC transporter
JHOFNEDM_01618 9.7e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JHOFNEDM_01619 7.7e-138 phnE 3.6.1.63 U Phosphonate ABC transporter permease
JHOFNEDM_01620 1e-143 phnE1 3.6.1.63 U ABC transporter permease
JHOFNEDM_01621 3.2e-144 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
JHOFNEDM_01622 5.5e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
JHOFNEDM_01623 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JHOFNEDM_01624 2.1e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
JHOFNEDM_01625 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JHOFNEDM_01626 1e-57 yabA L Involved in initiation control of chromosome replication
JHOFNEDM_01627 3.3e-186 holB 2.7.7.7 L DNA polymerase III
JHOFNEDM_01628 2.4e-53 yaaQ S Cyclic-di-AMP receptor
JHOFNEDM_01629 3.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JHOFNEDM_01630 2.5e-99 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
JHOFNEDM_01631 2e-220 ulaA 2.7.1.194 S PTS system sugar-specific permease component
JHOFNEDM_01632 1.1e-40 ulaB_1 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
JHOFNEDM_01633 1.1e-50 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JHOFNEDM_01634 5.6e-241 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JHOFNEDM_01635 2.2e-38 yaaL S Protein of unknown function (DUF2508)
JHOFNEDM_01636 2.1e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JHOFNEDM_01637 3.7e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JHOFNEDM_01638 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JHOFNEDM_01639 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JHOFNEDM_01640 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
JHOFNEDM_01641 6.5e-37 nrdH O Glutaredoxin
JHOFNEDM_01642 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHOFNEDM_01643 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHOFNEDM_01644 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
JHOFNEDM_01645 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JHOFNEDM_01646 9e-39 L nuclease
JHOFNEDM_01647 9.3e-178 F DNA/RNA non-specific endonuclease
JHOFNEDM_01648 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JHOFNEDM_01649 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JHOFNEDM_01650 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JHOFNEDM_01651 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JHOFNEDM_01652 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
JHOFNEDM_01653 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
JHOFNEDM_01654 5.8e-28 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
JHOFNEDM_01655 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JHOFNEDM_01656 2e-100 sigH K Sigma-70 region 2
JHOFNEDM_01657 5.3e-98 yacP S YacP-like NYN domain
JHOFNEDM_01658 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHOFNEDM_01659 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JHOFNEDM_01660 2.6e-269 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JHOFNEDM_01661 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JHOFNEDM_01662 3.7e-205 yacL S domain protein
JHOFNEDM_01663 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JHOFNEDM_01664 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
JHOFNEDM_01665 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
JHOFNEDM_01666 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JHOFNEDM_01667 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
JHOFNEDM_01668 1.8e-113 zmp2 O Zinc-dependent metalloprotease
JHOFNEDM_01669 7.2e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JHOFNEDM_01670 1.7e-177 EG EamA-like transporter family
JHOFNEDM_01671 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
JHOFNEDM_01672 4.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
JHOFNEDM_01673 1.8e-136 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
JHOFNEDM_01674 9.8e-141 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JHOFNEDM_01675 3.4e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
JHOFNEDM_01676 3.7e-64 accB 2.3.1.12 I Biotin-requiring enzyme
JHOFNEDM_01677 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JHOFNEDM_01678 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
JHOFNEDM_01679 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
JHOFNEDM_01680 0.0 levR K Sigma-54 interaction domain
JHOFNEDM_01681 4.7e-64 S Domain of unknown function (DUF956)
JHOFNEDM_01682 3.6e-171 manN G system, mannose fructose sorbose family IID component
JHOFNEDM_01683 3.4e-133 manY G PTS system
JHOFNEDM_01684 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
JHOFNEDM_01685 6.4e-156 G Peptidase_C39 like family
JHOFNEDM_01687 1.6e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JHOFNEDM_01688 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
JHOFNEDM_01689 5.2e-83 ydcK S Belongs to the SprT family
JHOFNEDM_01690 0.0 yhgF K Tex-like protein N-terminal domain protein
JHOFNEDM_01691 8.9e-72
JHOFNEDM_01692 0.0 pacL 3.6.3.8 P P-type ATPase
JHOFNEDM_01693 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JHOFNEDM_01694 3.4e-288 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JHOFNEDM_01695 4.6e-137 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
JHOFNEDM_01696 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
JHOFNEDM_01697 1e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JHOFNEDM_01698 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JHOFNEDM_01699 1.6e-151 pnuC H nicotinamide mononucleotide transporter
JHOFNEDM_01700 4.7e-194 ybiR P Citrate transporter
JHOFNEDM_01701 4.6e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
JHOFNEDM_01702 2.5e-53 S Cupin domain
JHOFNEDM_01703 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
JHOFNEDM_01705 7.3e-38 S Protein of unknown function (DUF1722)
JHOFNEDM_01706 1.9e-49 S Pyrimidine dimer DNA glycosylase
JHOFNEDM_01708 1.9e-42 K LytTr DNA-binding domain
JHOFNEDM_01709 4e-30 S Protein of unknown function (DUF3021)
JHOFNEDM_01710 6.6e-36
JHOFNEDM_01712 6.5e-55
JHOFNEDM_01713 7.4e-216 S Virulence-associated protein E
JHOFNEDM_01714 5.3e-123 L Primase C terminal 1 (PriCT-1)
JHOFNEDM_01715 3.5e-24
JHOFNEDM_01716 5.4e-37
JHOFNEDM_01718 1.3e-42
JHOFNEDM_01719 5.7e-81 S Phage regulatory protein Rha (Phage_pRha)
JHOFNEDM_01720 1.3e-24 S Phage regulatory protein Rha (Phage_pRha)
JHOFNEDM_01723 2.2e-178 sip L Belongs to the 'phage' integrase family
JHOFNEDM_01726 2e-151 yjjH S Calcineurin-like phosphoesterase
JHOFNEDM_01727 3e-252 dtpT U amino acid peptide transporter
JHOFNEDM_01730 1.1e-111 norB EGP Major Facilitator
JHOFNEDM_01731 2.2e-21
JHOFNEDM_01732 3.2e-20
JHOFNEDM_01733 4e-150 D CobQ CobB MinD ParA nucleotide binding domain protein
JHOFNEDM_01734 2.9e-35
JHOFNEDM_01735 1.1e-166 repA S Replication initiator protein A
JHOFNEDM_01736 2.1e-28
JHOFNEDM_01737 1.7e-124 S Fic/DOC family
JHOFNEDM_01738 3.1e-41
JHOFNEDM_01739 5.5e-27
JHOFNEDM_01740 5.4e-34
JHOFNEDM_01743 2.1e-98 soj D CobQ CobB MinD ParA nucleotide binding domain protein
JHOFNEDM_01744 6.7e-212 P Belongs to the ABC transporter superfamily
JHOFNEDM_01745 5.6e-247 G Bacterial extracellular solute-binding protein
JHOFNEDM_01746 1.7e-151 U Binding-protein-dependent transport system inner membrane component
JHOFNEDM_01747 1.5e-141 U Binding-protein-dependent transport system inner membrane component
JHOFNEDM_01748 3.3e-29 tnpR1 L Resolvase, N terminal domain
JHOFNEDM_01749 2.6e-56 L recombinase activity
JHOFNEDM_01752 4e-87 D CobQ CobB MinD ParA nucleotide binding domain protein
JHOFNEDM_01753 9.3e-108 K Primase C terminal 1 (PriCT-1)
JHOFNEDM_01754 1.1e-68 tnp2PF3 L manually curated
JHOFNEDM_01755 1.2e-50 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JHOFNEDM_01756 3.8e-163 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
JHOFNEDM_01757 2.3e-116 mutH L DNA mismatch repair enzyme MutH
JHOFNEDM_01758 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JHOFNEDM_01759 2e-177 xopQ 3.2.2.1, 3.2.2.8 F inosine-uridine preferring nucleoside hydrolase
JHOFNEDM_01760 4.1e-108 tra L Transposase and inactivated derivatives, IS30 family
JHOFNEDM_01762 2.5e-132 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
JHOFNEDM_01763 5.9e-102 ybfG M Domain of unknown function (DUF1906)
JHOFNEDM_01764 3.3e-17 ybfG M peptidoglycan-binding domain-containing protein
JHOFNEDM_01765 1.1e-131 D CobQ CobB MinD ParA nucleotide binding domain protein
JHOFNEDM_01767 5.8e-128 repA S Replication initiator protein A
JHOFNEDM_01768 3.8e-30
JHOFNEDM_01769 3.6e-07
JHOFNEDM_01771 4e-135 D Cellulose biosynthesis protein BcsQ
JHOFNEDM_01772 2.1e-99 K Primase C terminal 1 (PriCT-1)
JHOFNEDM_01773 7.6e-75 repA S Replication initiator protein A
JHOFNEDM_01774 4.9e-09
JHOFNEDM_01775 1e-78 S Initiator Replication protein
JHOFNEDM_01776 4.4e-07 S Enterocin A Immunity
JHOFNEDM_01777 2.1e-19
JHOFNEDM_01778 7.8e-46 pre D Plasmid recombination enzyme
JHOFNEDM_01779 1.2e-40
JHOFNEDM_01780 7.1e-84
JHOFNEDM_01781 4.3e-43 relB L Addiction module antitoxin, RelB DinJ family
JHOFNEDM_01783 1.2e-143 D CobQ CobB MinD ParA nucleotide binding domain protein
JHOFNEDM_01785 1.5e-178 arsB U Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JHOFNEDM_01786 2.5e-32 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
JHOFNEDM_01787 8.7e-145 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
JHOFNEDM_01788 9e-50
JHOFNEDM_01789 2e-121 M Glycosyl transferase family group 2
JHOFNEDM_01790 2.2e-105 M Glycosyl transferase family group 2
JHOFNEDM_01791 3e-276 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JHOFNEDM_01792 2.1e-157 xerD L Phage integrase, N-terminal SAM-like domain
JHOFNEDM_01793 4.2e-32 S YozE SAM-like fold
JHOFNEDM_01794 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHOFNEDM_01795 1.5e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
JHOFNEDM_01796 1.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
JHOFNEDM_01797 1.2e-177 K Transcriptional regulator
JHOFNEDM_01798 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JHOFNEDM_01799 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JHOFNEDM_01800 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JHOFNEDM_01801 2.2e-170 lacX 5.1.3.3 G Aldose 1-epimerase
JHOFNEDM_01802 2.3e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JHOFNEDM_01803 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JHOFNEDM_01804 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
JHOFNEDM_01805 2.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JHOFNEDM_01806 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHOFNEDM_01807 3.3e-158 dprA LU DNA protecting protein DprA
JHOFNEDM_01808 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JHOFNEDM_01809 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JHOFNEDM_01810 1.4e-228 XK27_05470 E Methionine synthase
JHOFNEDM_01811 2.3e-170 cpsY K Transcriptional regulator, LysR family
JHOFNEDM_01812 1.6e-126 L restriction endonuclease
JHOFNEDM_01813 1.9e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
JHOFNEDM_01814 7.4e-197 XK27_00915 C Luciferase-like monooxygenase
JHOFNEDM_01815 3.3e-251 emrY EGP Major facilitator Superfamily
JHOFNEDM_01816 3.5e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
JHOFNEDM_01817 3.4e-35 yozE S Belongs to the UPF0346 family
JHOFNEDM_01818 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
JHOFNEDM_01819 2.1e-150 ypmR E GDSL-like Lipase/Acylhydrolase
JHOFNEDM_01820 5.1e-148 DegV S EDD domain protein, DegV family
JHOFNEDM_01821 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JHOFNEDM_01822 1e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JHOFNEDM_01823 0.0 yfmR S ABC transporter, ATP-binding protein
JHOFNEDM_01824 9.6e-85
JHOFNEDM_01825 7.2e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JHOFNEDM_01826 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JHOFNEDM_01827 9.7e-149 3.1.3.102, 3.1.3.104 S hydrolase
JHOFNEDM_01828 4.7e-206 S Tetratricopeptide repeat protein
JHOFNEDM_01829 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JHOFNEDM_01830 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JHOFNEDM_01831 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
JHOFNEDM_01832 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JHOFNEDM_01833 2e-19 M Lysin motif
JHOFNEDM_01834 2e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
JHOFNEDM_01835 9.9e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
JHOFNEDM_01836 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JHOFNEDM_01837 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JHOFNEDM_01838 8.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JHOFNEDM_01839 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JHOFNEDM_01840 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JHOFNEDM_01841 1.1e-164 xerD D recombinase XerD
JHOFNEDM_01842 1.4e-169 cvfB S S1 domain
JHOFNEDM_01843 1.5e-74 yeaL S Protein of unknown function (DUF441)
JHOFNEDM_01844 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JHOFNEDM_01845 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JHOFNEDM_01846 0.0 dnaE 2.7.7.7 L DNA polymerase
JHOFNEDM_01847 5.6e-29 S Protein of unknown function (DUF2929)
JHOFNEDM_01849 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
JHOFNEDM_01850 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JHOFNEDM_01851 8.5e-198 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JHOFNEDM_01852 1.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
JHOFNEDM_01853 1.1e-220 M O-Antigen ligase
JHOFNEDM_01854 5.4e-120 drrB U ABC-2 type transporter
JHOFNEDM_01855 1.8e-165 drrA V ABC transporter
JHOFNEDM_01856 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
JHOFNEDM_01857 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
JHOFNEDM_01858 2.1e-61 P Rhodanese Homology Domain
JHOFNEDM_01859 3.6e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
JHOFNEDM_01860 5.7e-181
JHOFNEDM_01861 5.7e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
JHOFNEDM_01862 6.2e-182 C Zinc-binding dehydrogenase
JHOFNEDM_01863 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
JHOFNEDM_01864 8.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JHOFNEDM_01865 2.5e-240 EGP Major facilitator Superfamily
JHOFNEDM_01866 4.3e-77 K Transcriptional regulator
JHOFNEDM_01867 7e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
JHOFNEDM_01868 5.8e-176 tanA S alpha beta
JHOFNEDM_01869 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
JHOFNEDM_01870 8e-137 K DeoR C terminal sensor domain
JHOFNEDM_01871 1.7e-108 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
JHOFNEDM_01872 9.1e-71 yneH 1.20.4.1 P ArsC family
JHOFNEDM_01873 1.4e-68 S Protein of unknown function (DUF1722)
JHOFNEDM_01874 1.2e-112 GM epimerase
JHOFNEDM_01875 0.0 CP_1020 S Zinc finger, swim domain protein
JHOFNEDM_01876 7.8e-81 K Bacterial regulatory proteins, tetR family
JHOFNEDM_01877 6.2e-214 S membrane
JHOFNEDM_01878 9.4e-15 K Bacterial regulatory proteins, tetR family
JHOFNEDM_01879 3.4e-72 S Alpha/beta hydrolase of unknown function (DUF915)
JHOFNEDM_01880 1.1e-07 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHOFNEDM_01881 3.5e-09 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHOFNEDM_01882 2.3e-113 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
JHOFNEDM_01883 2.9e-76 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
JHOFNEDM_01884 3.8e-128 K Helix-turn-helix domain, rpiR family
JHOFNEDM_01885 1e-159 S Alpha beta hydrolase
JHOFNEDM_01886 1.4e-113 GM NmrA-like family
JHOFNEDM_01887 8.3e-78 S Uncharacterized protein conserved in bacteria (DUF2255)
JHOFNEDM_01888 1.9e-161 K Transcriptional regulator
JHOFNEDM_01889 1.9e-172 C nadph quinone reductase
JHOFNEDM_01890 2.8e-14 S Alpha beta hydrolase
JHOFNEDM_01891 2.3e-270 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
JHOFNEDM_01892 1.2e-103 desR K helix_turn_helix, Lux Regulon
JHOFNEDM_01893 8.2e-207 desK 2.7.13.3 T Histidine kinase
JHOFNEDM_01894 3.1e-136 yvfS V ABC-2 type transporter
JHOFNEDM_01895 1.1e-156 yvfR V ABC transporter
JHOFNEDM_01897 6e-82 K Acetyltransferase (GNAT) domain
JHOFNEDM_01898 6.2e-73 K MarR family
JHOFNEDM_01899 2.4e-50 S Psort location CytoplasmicMembrane, score
JHOFNEDM_01900 2.6e-12 yjdF S Protein of unknown function (DUF2992)
JHOFNEDM_01901 3.9e-162 V ABC transporter, ATP-binding protein
JHOFNEDM_01902 9.8e-127 S ABC-2 family transporter protein
JHOFNEDM_01903 5.1e-198
JHOFNEDM_01904 1.1e-200
JHOFNEDM_01905 4.8e-165 ytrB V ABC transporter, ATP-binding protein
JHOFNEDM_01906 1.4e-63 K helix_turn_helix gluconate operon transcriptional repressor
JHOFNEDM_01907 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JHOFNEDM_01908 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JHOFNEDM_01909 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JHOFNEDM_01910 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JHOFNEDM_01911 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
JHOFNEDM_01912 5.6e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JHOFNEDM_01913 2.9e-72 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JHOFNEDM_01914 6.6e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JHOFNEDM_01915 5.8e-180 phoH T phosphate starvation-inducible protein PhoH
JHOFNEDM_01916 2.6e-71 yqeY S YqeY-like protein
JHOFNEDM_01917 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JHOFNEDM_01918 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
JHOFNEDM_01919 1.7e-128 C Enoyl-(Acyl carrier protein) reductase
JHOFNEDM_01920 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JHOFNEDM_01921 2.9e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
JHOFNEDM_01922 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHOFNEDM_01923 1.6e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHOFNEDM_01924 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
JHOFNEDM_01925 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
JHOFNEDM_01926 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JHOFNEDM_01927 7.8e-165 yniA G Fructosamine kinase
JHOFNEDM_01928 7.9e-114 3.1.3.18 J HAD-hyrolase-like
JHOFNEDM_01929 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JHOFNEDM_01930 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JHOFNEDM_01931 9.6e-58
JHOFNEDM_01932 1.1e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JHOFNEDM_01933 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
JHOFNEDM_01934 3.6e-114 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
JHOFNEDM_01935 1.4e-49
JHOFNEDM_01936 1.4e-49
JHOFNEDM_01937 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JHOFNEDM_01938 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JHOFNEDM_01939 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHOFNEDM_01940 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
JHOFNEDM_01941 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHOFNEDM_01942 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
JHOFNEDM_01943 4.4e-198 pbpX2 V Beta-lactamase
JHOFNEDM_01944 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JHOFNEDM_01945 0.0 dnaK O Heat shock 70 kDa protein
JHOFNEDM_01946 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JHOFNEDM_01947 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JHOFNEDM_01948 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
JHOFNEDM_01949 1.2e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JHOFNEDM_01950 9.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JHOFNEDM_01951 2.4e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JHOFNEDM_01952 1.9e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
JHOFNEDM_01953 2.9e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JHOFNEDM_01954 1.9e-92
JHOFNEDM_01955 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JHOFNEDM_01956 3.3e-264 ydiN 5.4.99.5 G Major Facilitator
JHOFNEDM_01957 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JHOFNEDM_01958 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JHOFNEDM_01959 1.1e-47 ylxQ J ribosomal protein
JHOFNEDM_01960 9.5e-49 ylxR K Protein of unknown function (DUF448)
JHOFNEDM_01961 3.3e-217 nusA K Participates in both transcription termination and antitermination
JHOFNEDM_01962 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
JHOFNEDM_01963 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JHOFNEDM_01964 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JHOFNEDM_01965 3.6e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
JHOFNEDM_01966 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
JHOFNEDM_01967 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JHOFNEDM_01968 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JHOFNEDM_01969 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JHOFNEDM_01970 3.9e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JHOFNEDM_01971 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
JHOFNEDM_01972 4.7e-134 S Haloacid dehalogenase-like hydrolase
JHOFNEDM_01973 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHOFNEDM_01974 2e-49 yazA L GIY-YIG catalytic domain protein
JHOFNEDM_01975 4.2e-133 yabB 2.1.1.223 L Methyltransferase small domain
JHOFNEDM_01976 1.2e-117 plsC 2.3.1.51 I Acyltransferase
JHOFNEDM_01977 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
JHOFNEDM_01978 2.9e-36 ynzC S UPF0291 protein
JHOFNEDM_01979 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JHOFNEDM_01980 3.2e-86
JHOFNEDM_01981 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
JHOFNEDM_01982 1.1e-76
JHOFNEDM_01983 3.5e-67
JHOFNEDM_01984 3.4e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
JHOFNEDM_01987 7.2e-17 S Short C-terminal domain
JHOFNEDM_01988 1.1e-23 S Short C-terminal domain
JHOFNEDM_01990 4.9e-43 L HTH-like domain
JHOFNEDM_01991 9.8e-36 L transposase activity
JHOFNEDM_01992 4e-50 L Belongs to the 'phage' integrase family
JHOFNEDM_01995 1.6e-31
JHOFNEDM_01996 2.1e-140 Q Methyltransferase
JHOFNEDM_01997 8.5e-57 ybjQ S Belongs to the UPF0145 family
JHOFNEDM_01998 7.2e-212 EGP Major facilitator Superfamily
JHOFNEDM_01999 1.5e-103 K Helix-turn-helix domain
JHOFNEDM_02000 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JHOFNEDM_02001 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
JHOFNEDM_02002 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
JHOFNEDM_02003 5.6e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JHOFNEDM_02004 2.8e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JHOFNEDM_02005 3.2e-46
JHOFNEDM_02006 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JHOFNEDM_02007 2.2e-134 fruR K DeoR C terminal sensor domain
JHOFNEDM_02008 5.1e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
JHOFNEDM_02009 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
JHOFNEDM_02010 5.4e-253 cpdA S Calcineurin-like phosphoesterase
JHOFNEDM_02011 1.4e-262 cps4J S Polysaccharide biosynthesis protein
JHOFNEDM_02012 5.1e-176 cps4I M Glycosyltransferase like family 2
JHOFNEDM_02013 5.6e-231
JHOFNEDM_02014 1.1e-184 cps4G M Glycosyltransferase Family 4
JHOFNEDM_02015 1.2e-202 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
JHOFNEDM_02016 1.8e-127 tuaA M Bacterial sugar transferase
JHOFNEDM_02017 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
JHOFNEDM_02018 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
JHOFNEDM_02019 7.3e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
JHOFNEDM_02020 2.9e-126 epsB M biosynthesis protein
JHOFNEDM_02021 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JHOFNEDM_02022 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JHOFNEDM_02023 9.2e-270 glnPH2 P ABC transporter permease
JHOFNEDM_02024 4.3e-22
JHOFNEDM_02025 9.9e-73 S Iron-sulphur cluster biosynthesis
JHOFNEDM_02026 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
JHOFNEDM_02027 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
JHOFNEDM_02028 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JHOFNEDM_02029 4.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JHOFNEDM_02030 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JHOFNEDM_02031 1.1e-159 S Tetratricopeptide repeat
JHOFNEDM_02032 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JHOFNEDM_02033 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JHOFNEDM_02034 6.3e-192 mdtG EGP Major Facilitator Superfamily
JHOFNEDM_02035 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JHOFNEDM_02036 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
JHOFNEDM_02037 1.1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
JHOFNEDM_02038 0.0 comEC S Competence protein ComEC
JHOFNEDM_02039 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
JHOFNEDM_02040 1.2e-121 comEA L Competence protein ComEA
JHOFNEDM_02041 9.6e-197 ylbL T Belongs to the peptidase S16 family
JHOFNEDM_02042 2.1e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JHOFNEDM_02043 1.7e-102 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
JHOFNEDM_02044 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
JHOFNEDM_02045 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JHOFNEDM_02046 1.6e-205 ftsW D Belongs to the SEDS family
JHOFNEDM_02047 2.8e-185
JHOFNEDM_02048 6e-120 ica2 GT2 M Glycosyl transferase family group 2
JHOFNEDM_02049 0.0 typA T GTP-binding protein TypA
JHOFNEDM_02050 6.3e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
JHOFNEDM_02051 3.6e-45 yktA S Belongs to the UPF0223 family
JHOFNEDM_02052 1.4e-162 1.1.1.27 C L-malate dehydrogenase activity
JHOFNEDM_02053 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
JHOFNEDM_02054 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JHOFNEDM_02055 4.5e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
JHOFNEDM_02056 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
JHOFNEDM_02057 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JHOFNEDM_02058 1.6e-85
JHOFNEDM_02059 3.1e-33 ykzG S Belongs to the UPF0356 family
JHOFNEDM_02060 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JHOFNEDM_02061 1.7e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
JHOFNEDM_02062 3.7e-28
JHOFNEDM_02063 2e-58 L MobA MobL family protein
JHOFNEDM_02064 3.1e-153 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
JHOFNEDM_02065 2.3e-31 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
JHOFNEDM_02066 1e-187 L Helix-turn-helix domain
JHOFNEDM_02067 2.7e-48 GT4 M Glycosyl transferases group 1
JHOFNEDM_02068 5.1e-246 cycA E Amino acid permease
JHOFNEDM_02069 2.8e-120 repA S Replication initiator protein A
JHOFNEDM_02070 1.2e-26
JHOFNEDM_02071 1.6e-26
JHOFNEDM_02072 3.1e-41
JHOFNEDM_02073 6.6e-27
JHOFNEDM_02074 7.4e-43 relB L Addiction module antitoxin, RelB DinJ family
JHOFNEDM_02075 3e-97 repA S Replication initiator protein A
JHOFNEDM_02076 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
JHOFNEDM_02077 1.5e-167 L Replication protein
JHOFNEDM_02079 1.5e-42 S COG NOG38524 non supervised orthologous group
JHOFNEDM_02080 1.3e-271 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
JHOFNEDM_02081 3.7e-14 tnpR1 L Resolvase, N terminal domain
JHOFNEDM_02082 3e-63 tnpR1 L Resolvase, N terminal domain
JHOFNEDM_02083 3.2e-277 S Psort location CytoplasmicMembrane, score
JHOFNEDM_02084 2.6e-07 S Enterocin A Immunity
JHOFNEDM_02085 1e-124 S Plasmid replication protein
JHOFNEDM_02086 3.9e-17
JHOFNEDM_02087 2.3e-93 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
JHOFNEDM_02088 4.1e-108 mltD CBM50 M NlpC P60 family protein
JHOFNEDM_02089 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JHOFNEDM_02090 2.3e-164 ptlF S KR domain
JHOFNEDM_02091 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
JHOFNEDM_02092 1.3e-122 drgA C Nitroreductase family
JHOFNEDM_02093 1.3e-290 QT PucR C-terminal helix-turn-helix domain
JHOFNEDM_02094 5.5e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
JHOFNEDM_02095 1.1e-194 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
JHOFNEDM_02096 7.4e-250 yjjP S Putative threonine/serine exporter
JHOFNEDM_02097 1.7e-134 wzb 3.1.3.48 T Tyrosine phosphatase family
JHOFNEDM_02098 1.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
JHOFNEDM_02099 2.9e-81 6.3.3.2 S ASCH
JHOFNEDM_02100 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
JHOFNEDM_02101 1.8e-170 yobV1 K WYL domain
JHOFNEDM_02102 1e-116 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JHOFNEDM_02103 0.0 tetP J elongation factor G
JHOFNEDM_02104 8.2e-39 S Protein of unknown function
JHOFNEDM_02105 2.7e-61 S Protein of unknown function
JHOFNEDM_02106 3.6e-152 EG EamA-like transporter family
JHOFNEDM_02107 3.6e-93 MA20_25245 K FR47-like protein
JHOFNEDM_02108 2e-126 hchA S DJ-1/PfpI family
JHOFNEDM_02109 1.6e-180 1.1.1.1 C nadph quinone reductase
JHOFNEDM_02110 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
JHOFNEDM_02111 4.3e-234 mepA V MATE efflux family protein
JHOFNEDM_02112 2.5e-166 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
JHOFNEDM_02113 1e-139 S Belongs to the UPF0246 family
JHOFNEDM_02114 6e-76
JHOFNEDM_02115 2.7e-310 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
JHOFNEDM_02116 1.2e-140
JHOFNEDM_02118 7e-110 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
JHOFNEDM_02119 4.8e-40
JHOFNEDM_02120 1.9e-127 cbiO P ABC transporter
JHOFNEDM_02121 2.6e-149 P Cobalt transport protein
JHOFNEDM_02122 2.6e-172 nikMN P PDGLE domain
JHOFNEDM_02123 4.2e-121 K Crp-like helix-turn-helix domain
JHOFNEDM_02124 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
JHOFNEDM_02125 2.4e-125 larB S AIR carboxylase
JHOFNEDM_02126 6.3e-132 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JHOFNEDM_02127 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
JHOFNEDM_02128 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
JHOFNEDM_02129 2.8e-151 larE S NAD synthase
JHOFNEDM_02130 8.7e-176 1.6.5.5 C Zinc-binding dehydrogenase
JHOFNEDM_02131 2.2e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JHOFNEDM_02132 9.1e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JHOFNEDM_02133 7.3e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
JHOFNEDM_02134 1.9e-204 cytX U Belongs to the purine-cytosine permease (2.A.39) family
JHOFNEDM_02135 5.1e-136 S peptidase C26
JHOFNEDM_02136 4e-303 L HIRAN domain
JHOFNEDM_02137 9.9e-85 F NUDIX domain
JHOFNEDM_02138 2.6e-250 yifK E Amino acid permease
JHOFNEDM_02139 1.7e-120
JHOFNEDM_02140 5.6e-149 ydjP I Alpha/beta hydrolase family
JHOFNEDM_02141 0.0 pacL1 P P-type ATPase
JHOFNEDM_02142 1.6e-28 KT PspC domain
JHOFNEDM_02143 3e-110 S NADPH-dependent FMN reductase
JHOFNEDM_02144 1.9e-75 papX3 K Transcriptional regulator
JHOFNEDM_02145 1.7e-72 hsp1 O Belongs to the small heat shock protein (HSP20) family
JHOFNEDM_02146 4.2e-80 S Protein of unknown function (DUF3021)
JHOFNEDM_02147 4.7e-227 mdtG EGP Major facilitator Superfamily
JHOFNEDM_02148 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
JHOFNEDM_02149 8.1e-216 yeaN P Transporter, major facilitator family protein
JHOFNEDM_02151 2.9e-159 S reductase
JHOFNEDM_02152 3.6e-165 1.1.1.65 C Aldo keto reductase
JHOFNEDM_02153 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
JHOFNEDM_02154 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
JHOFNEDM_02155 5e-52
JHOFNEDM_02156 1.7e-258
JHOFNEDM_02157 1.5e-208 C Oxidoreductase
JHOFNEDM_02158 2.4e-150 cbiQ P cobalt transport
JHOFNEDM_02159 0.0 ykoD P ABC transporter, ATP-binding protein
JHOFNEDM_02160 2.5e-98 S UPF0397 protein
JHOFNEDM_02161 1.6e-129 K UbiC transcription regulator-associated domain protein
JHOFNEDM_02162 4.1e-53 K Transcriptional regulator PadR-like family
JHOFNEDM_02163 4.6e-143
JHOFNEDM_02164 7.6e-149
JHOFNEDM_02165 9.1e-89
JHOFNEDM_02166 5.5e-144 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
JHOFNEDM_02167 2.3e-170 yjjC V ABC transporter
JHOFNEDM_02168 7.2e-300 M Exporter of polyketide antibiotics
JHOFNEDM_02169 1.6e-117 K Transcriptional regulator
JHOFNEDM_02170 4.7e-277 C Electron transfer flavoprotein FAD-binding domain
JHOFNEDM_02171 1.1e-73 folT 2.7.13.3 T ECF transporter, substrate-specific component
JHOFNEDM_02173 2.4e-92 K Bacterial regulatory proteins, tetR family
JHOFNEDM_02174 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
JHOFNEDM_02175 5e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
JHOFNEDM_02176 1.9e-101 dhaL 2.7.1.121 S Dak2
JHOFNEDM_02177 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
JHOFNEDM_02178 8.6e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
JHOFNEDM_02179 1e-190 malR K Transcriptional regulator, LacI family
JHOFNEDM_02180 4.4e-180 yvdE K helix_turn _helix lactose operon repressor
JHOFNEDM_02181 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
JHOFNEDM_02182 2.1e-230 mdxE G Bacterial extracellular solute-binding protein
JHOFNEDM_02183 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
JHOFNEDM_02184 1.4e-161 malD P ABC transporter permease
JHOFNEDM_02185 1.8e-150 malA S maltodextrose utilization protein MalA
JHOFNEDM_02186 9.1e-261 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
JHOFNEDM_02187 4e-209 msmK P Belongs to the ABC transporter superfamily
JHOFNEDM_02188 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
JHOFNEDM_02189 0.0 3.2.1.96 G Glycosyl hydrolase family 85
JHOFNEDM_02190 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
JHOFNEDM_02191 1.8e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
JHOFNEDM_02192 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
JHOFNEDM_02193 1.4e-305 scrB 3.2.1.26 GH32 G invertase
JHOFNEDM_02194 9.1e-173 scrR K Transcriptional regulator, LacI family
JHOFNEDM_02195 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
JHOFNEDM_02196 1.7e-165 3.5.1.10 C nadph quinone reductase
JHOFNEDM_02197 1.1e-217 nhaC C Na H antiporter NhaC
JHOFNEDM_02198 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
JHOFNEDM_02199 7.7e-166 mleR K LysR substrate binding domain
JHOFNEDM_02200 5.1e-236 3.6.4.13 M domain protein
JHOFNEDM_02201 7.3e-101 3.6.4.13 M domain protein
JHOFNEDM_02203 2.1e-157 hipB K Helix-turn-helix
JHOFNEDM_02204 0.0 oppA E ABC transporter, substratebinding protein
JHOFNEDM_02205 7.8e-310 oppA E ABC transporter, substratebinding protein
JHOFNEDM_02206 7.7e-79 yiaC K Acetyltransferase (GNAT) domain
JHOFNEDM_02207 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHOFNEDM_02208 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JHOFNEDM_02209 6.7e-113 pgm1 G phosphoglycerate mutase
JHOFNEDM_02210 1e-179 yghZ C Aldo keto reductase family protein
JHOFNEDM_02211 4.9e-34
JHOFNEDM_02212 1.3e-60 S Domain of unknown function (DU1801)
JHOFNEDM_02213 3.8e-162 FbpA K Domain of unknown function (DUF814)
JHOFNEDM_02214 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHOFNEDM_02216 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JHOFNEDM_02217 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JHOFNEDM_02218 2.9e-258 S ATPases associated with a variety of cellular activities
JHOFNEDM_02219 2.4e-61
JHOFNEDM_02220 1.5e-115 P cobalt transport
JHOFNEDM_02221 2e-258 P ABC transporter
JHOFNEDM_02222 3.1e-101 S ABC transporter permease
JHOFNEDM_02223 6.9e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
JHOFNEDM_02224 4.1e-158 dkgB S reductase
JHOFNEDM_02225 4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JHOFNEDM_02226 1e-69
JHOFNEDM_02227 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JHOFNEDM_02228 4.5e-174 P Major Facilitator Superfamily
JHOFNEDM_02229 1.3e-223 1.3.5.4 C FAD dependent oxidoreductase
JHOFNEDM_02230 4.8e-99 K Helix-turn-helix domain
JHOFNEDM_02231 3.9e-278 pipD E Dipeptidase
JHOFNEDM_02232 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
JHOFNEDM_02233 0.0 mtlR K Mga helix-turn-helix domain
JHOFNEDM_02234 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHOFNEDM_02235 2.8e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
JHOFNEDM_02236 2.1e-73
JHOFNEDM_02237 6.2e-57 trxA1 O Belongs to the thioredoxin family
JHOFNEDM_02238 6.1e-49
JHOFNEDM_02239 6.6e-96
JHOFNEDM_02240 2e-62
JHOFNEDM_02241 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
JHOFNEDM_02242 7.6e-255 S Uncharacterized protein conserved in bacteria (DUF2252)
JHOFNEDM_02243 3.5e-97 yieF S NADPH-dependent FMN reductase
JHOFNEDM_02244 6.1e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
JHOFNEDM_02245 9.8e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JHOFNEDM_02246 5.8e-166 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JHOFNEDM_02247 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
JHOFNEDM_02248 4.3e-141 pnuC H nicotinamide mononucleotide transporter
JHOFNEDM_02249 7.3e-43 S Protein of unknown function (DUF2089)
JHOFNEDM_02250 1.7e-42
JHOFNEDM_02251 3.5e-129 treR K UTRA
JHOFNEDM_02252 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
JHOFNEDM_02253 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
JHOFNEDM_02254 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
JHOFNEDM_02255 1.4e-144
JHOFNEDM_02256 6.3e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
JHOFNEDM_02257 1.3e-69
JHOFNEDM_02258 1.8e-72 K Transcriptional regulator
JHOFNEDM_02259 5.7e-121 K Bacterial regulatory proteins, tetR family
JHOFNEDM_02260 8.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
JHOFNEDM_02261 5.5e-118
JHOFNEDM_02262 2e-41
JHOFNEDM_02263 1e-40
JHOFNEDM_02264 9.7e-253 ydiC1 EGP Major facilitator Superfamily
JHOFNEDM_02265 3.3e-65 K helix_turn_helix, mercury resistance
JHOFNEDM_02266 6.8e-251 T PhoQ Sensor
JHOFNEDM_02267 6.4e-128 K Transcriptional regulatory protein, C terminal
JHOFNEDM_02268 1.8e-49
JHOFNEDM_02269 2.1e-129 yidA K Helix-turn-helix domain, rpiR family
JHOFNEDM_02270 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHOFNEDM_02271 9.9e-57
JHOFNEDM_02272 2.1e-41
JHOFNEDM_02273 1.6e-183 brpA K Cell envelope-like function transcriptional attenuator common domain protein
JHOFNEDM_02274 2e-258 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
JHOFNEDM_02275 1.3e-47
JHOFNEDM_02276 2.7e-123 2.7.6.5 S RelA SpoT domain protein
JHOFNEDM_02277 1.2e-103 K transcriptional regulator
JHOFNEDM_02278 0.0 ydgH S MMPL family
JHOFNEDM_02279 1.1e-106 tag 3.2.2.20 L glycosylase
JHOFNEDM_02280 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
JHOFNEDM_02281 2e-192 yclI V MacB-like periplasmic core domain
JHOFNEDM_02282 7.1e-121 yclH V ABC transporter
JHOFNEDM_02283 1.6e-113 V CAAX protease self-immunity
JHOFNEDM_02284 1.6e-118 S CAAX protease self-immunity
JHOFNEDM_02285 1.7e-52 M Lysin motif
JHOFNEDM_02286 9.4e-54 lytE M LysM domain protein
JHOFNEDM_02287 7.4e-67 gcvH E Glycine cleavage H-protein
JHOFNEDM_02288 7.4e-177 sepS16B
JHOFNEDM_02289 1.3e-131
JHOFNEDM_02290 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
JHOFNEDM_02291 6.8e-57
JHOFNEDM_02292 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHOFNEDM_02293 3.8e-78 elaA S GNAT family
JHOFNEDM_02294 1.7e-75 K Transcriptional regulator
JHOFNEDM_02295 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
JHOFNEDM_02296 2.6e-37
JHOFNEDM_02297 2.5e-08 S Motility quorum-sensing regulator, toxin of MqsA
JHOFNEDM_02298 2.2e-30
JHOFNEDM_02299 7.1e-21 U Preprotein translocase subunit SecB
JHOFNEDM_02300 4e-206 potD P ABC transporter
JHOFNEDM_02301 3.4e-141 potC P ABC transporter permease
JHOFNEDM_02302 2.7e-149 potB P ABC transporter permease
JHOFNEDM_02303 3.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JHOFNEDM_02304 3.8e-96 puuR K Cupin domain
JHOFNEDM_02305 1.1e-83 6.3.3.2 S ASCH
JHOFNEDM_02306 1e-84 K GNAT family
JHOFNEDM_02307 3e-90 K acetyltransferase
JHOFNEDM_02308 8.1e-22
JHOFNEDM_02309 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
JHOFNEDM_02310 2e-163 ytrB V ABC transporter
JHOFNEDM_02311 4.9e-190
JHOFNEDM_02312 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
JHOFNEDM_02313 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
JHOFNEDM_02315 2.3e-240 xylP1 G MFS/sugar transport protein
JHOFNEDM_02316 6.7e-122 qmcA O prohibitin homologues
JHOFNEDM_02317 1.1e-29
JHOFNEDM_02318 2.5e-280 pipD E Dipeptidase
JHOFNEDM_02319 3e-40
JHOFNEDM_02320 6.8e-96 bioY S BioY family
JHOFNEDM_02321 1e-176 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JHOFNEDM_02322 1.4e-59 S CHY zinc finger
JHOFNEDM_02323 2.2e-111 metQ P NLPA lipoprotein
JHOFNEDM_02324 8.7e-126 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JHOFNEDM_02325 1.3e-85 metI U Binding-protein-dependent transport system inner membrane component
JHOFNEDM_02326 7.7e-148 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JHOFNEDM_02327 1.2e-224 mtnE 2.6.1.83 E Aminotransferase
JHOFNEDM_02328 1.4e-217
JHOFNEDM_02329 3.5e-154 tagG U Transport permease protein
JHOFNEDM_02330 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JHOFNEDM_02331 3.5e-36 M Glycosyl transferase family 2
JHOFNEDM_02332 7e-117 plnP S CAAX protease self-immunity
JHOFNEDM_02333 2.5e-26
JHOFNEDM_02334 4.3e-18 plnA
JHOFNEDM_02335 6.9e-33 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JHOFNEDM_02336 2.3e-98 S Plasmid replication protein
JHOFNEDM_02338 2e-32
JHOFNEDM_02340 5.7e-23 M domain protein
JHOFNEDM_02341 1e-51 M domain protein
JHOFNEDM_02342 6e-140 K Helix-turn-helix domain
JHOFNEDM_02343 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JHOFNEDM_02344 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
JHOFNEDM_02345 2.4e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
JHOFNEDM_02346 0.0 ctpA 3.6.3.54 P P-type ATPase
JHOFNEDM_02347 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
JHOFNEDM_02348 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
JHOFNEDM_02349 3.9e-66 lysM M LysM domain
JHOFNEDM_02350 2.8e-266 yjeM E Amino Acid
JHOFNEDM_02351 1.5e-144 K Helix-turn-helix XRE-family like proteins
JHOFNEDM_02352 1.4e-69
JHOFNEDM_02354 5e-162 IQ KR domain
JHOFNEDM_02355 8.3e-229 amd 3.5.1.47 E Peptidase family M20/M25/M40
JHOFNEDM_02356 9.1e-177 O protein import
JHOFNEDM_02357 4.8e-311 XK27_09600 V ABC transporter, ATP-binding protein
JHOFNEDM_02358 0.0 V ABC transporter
JHOFNEDM_02359 8.6e-218 ykiI
JHOFNEDM_02360 1.1e-116 GM NAD(P)H-binding
JHOFNEDM_02361 2.4e-53 IQ reductase
JHOFNEDM_02362 1e-66 IQ reductase
JHOFNEDM_02363 3.7e-60 I sulfurtransferase activity
JHOFNEDM_02364 2.7e-78 yphH S Cupin domain
JHOFNEDM_02365 4.7e-93 S Phosphatidylethanolamine-binding protein
JHOFNEDM_02366 1.6e-117 GM NAD(P)H-binding
JHOFNEDM_02367 1.6e-175 C C4-dicarboxylate transmembrane transporter activity
JHOFNEDM_02368 3.8e-131 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JHOFNEDM_02369 1.2e-166 K Bacterial regulatory helix-turn-helix protein, lysR family
JHOFNEDM_02370 2e-283 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
JHOFNEDM_02371 1.2e-73 S Psort location Cytoplasmic, score
JHOFNEDM_02372 3.7e-218 T diguanylate cyclase
JHOFNEDM_02373 2.6e-120 tag 3.2.2.20 L Methyladenine glycosylase
JHOFNEDM_02374 3.6e-91
JHOFNEDM_02375 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
JHOFNEDM_02376 1.8e-54 nudA S ASCH
JHOFNEDM_02377 4e-107 S SdpI/YhfL protein family
JHOFNEDM_02378 6.3e-93 M Lysin motif
JHOFNEDM_02379 2.3e-65 M LysM domain
JHOFNEDM_02380 5.1e-75 K helix_turn_helix, mercury resistance
JHOFNEDM_02381 1.7e-185 1.1.1.219 GM Male sterility protein
JHOFNEDM_02382 2e-279 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHOFNEDM_02383 3.3e-267 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHOFNEDM_02384 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
JHOFNEDM_02385 8.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
JHOFNEDM_02386 2e-149 dicA K Helix-turn-helix domain
JHOFNEDM_02387 3.2e-55
JHOFNEDM_02388 3.4e-160 T Calcineurin-like phosphoesterase superfamily domain
JHOFNEDM_02389 7.4e-64
JHOFNEDM_02390 6.3e-141 P Concanavalin A-like lectin/glucanases superfamily
JHOFNEDM_02391 0.0 P Concanavalin A-like lectin/glucanases superfamily
JHOFNEDM_02392 0.0 yhcA V ABC transporter, ATP-binding protein
JHOFNEDM_02393 1.6e-92 cadD P Cadmium resistance transporter
JHOFNEDM_02394 1.9e-47 K Transcriptional regulator, ArsR family
JHOFNEDM_02395 1.9e-116 S SNARE associated Golgi protein
JHOFNEDM_02396 1.1e-46
JHOFNEDM_02397 6.8e-72 T Belongs to the universal stress protein A family
JHOFNEDM_02398 2.1e-283 mntH P H( )-stimulated, divalent metal cation uptake system
JHOFNEDM_02399 2.2e-122 K Helix-turn-helix XRE-family like proteins
JHOFNEDM_02400 2.8e-82 gtrA S GtrA-like protein
JHOFNEDM_02401 1.7e-113 zmp3 O Zinc-dependent metalloprotease
JHOFNEDM_02402 2e-32
JHOFNEDM_02404 5.4e-212 livJ E Receptor family ligand binding region
JHOFNEDM_02405 6.5e-154 livH U Branched-chain amino acid transport system / permease component
JHOFNEDM_02406 9e-141 livM E Branched-chain amino acid transport system / permease component
JHOFNEDM_02407 1.8e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
JHOFNEDM_02408 2.1e-123 livF E ABC transporter
JHOFNEDM_02409 2.4e-97 acuB S Domain in cystathionine beta-synthase and other proteins.
JHOFNEDM_02410 1e-91 S WxL domain surface cell wall-binding
JHOFNEDM_02411 9.1e-27 S Cell surface protein
JHOFNEDM_02412 7.2e-144 S Cell surface protein
JHOFNEDM_02413 8.2e-61
JHOFNEDM_02414 1e-260
JHOFNEDM_02415 3.5e-169 XK27_00670 S ABC transporter
JHOFNEDM_02416 2.4e-152 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
JHOFNEDM_02417 8.1e-109 cmpC S ATPases associated with a variety of cellular activities
JHOFNEDM_02418 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
JHOFNEDM_02419 5e-119 drgA C Nitroreductase family
JHOFNEDM_02420 2.9e-96 rmaB K Transcriptional regulator, MarR family
JHOFNEDM_02421 0.0 lmrA 3.6.3.44 V ABC transporter
JHOFNEDM_02422 2.5e-161 ypbG 2.7.1.2 GK ROK family
JHOFNEDM_02423 1.4e-47 3.6.4.12 K HxlR-like helix-turn-helix
JHOFNEDM_02424 2.1e-111 K Transcriptional regulator C-terminal region
JHOFNEDM_02425 7.5e-177 4.1.1.52 S Amidohydrolase
JHOFNEDM_02426 4.4e-129 E lipolytic protein G-D-S-L family
JHOFNEDM_02427 1.1e-159 yicL EG EamA-like transporter family
JHOFNEDM_02428 2.1e-223 sdrF M Collagen binding domain
JHOFNEDM_02429 9.7e-269 I acetylesterase activity
JHOFNEDM_02430 5.2e-177 S Phosphotransferase system, EIIC
JHOFNEDM_02431 2.7e-137 aroD S Alpha/beta hydrolase family
JHOFNEDM_02432 3.2e-37
JHOFNEDM_02434 8.8e-136 S zinc-ribbon domain
JHOFNEDM_02435 1.3e-265 S response to antibiotic
JHOFNEDM_02436 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
JHOFNEDM_02437 2.4e-243 P Sodium:sulfate symporter transmembrane region
JHOFNEDM_02438 2.2e-165 K LysR substrate binding domain
JHOFNEDM_02439 4.4e-79
JHOFNEDM_02440 4.9e-22
JHOFNEDM_02441 1.5e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHOFNEDM_02442 6.8e-192 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JHOFNEDM_02443 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
JHOFNEDM_02444 2e-80
JHOFNEDM_02445 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
JHOFNEDM_02446 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHOFNEDM_02447 2.6e-126 yliE T EAL domain
JHOFNEDM_02448 6.2e-218 2.7.7.65 T Diguanylate cyclase, GGDEF domain
JHOFNEDM_02449 1.7e-88 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
JHOFNEDM_02450 5.6e-39 S Cytochrome B5
JHOFNEDM_02451 1.6e-237
JHOFNEDM_02452 7e-130 treR K UTRA
JHOFNEDM_02453 1.7e-159 I alpha/beta hydrolase fold
JHOFNEDM_02454 1.6e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
JHOFNEDM_02455 1.5e-233 yxiO S Vacuole effluxer Atg22 like
JHOFNEDM_02456 2.4e-172 ropB K Helix-turn-helix XRE-family like proteins
JHOFNEDM_02457 4.8e-208 EGP Major facilitator Superfamily
JHOFNEDM_02458 0.0 uvrA3 L excinuclease ABC
JHOFNEDM_02459 0.0 S Predicted membrane protein (DUF2207)
JHOFNEDM_02460 2.4e-147 3.1.3.102, 3.1.3.104 S hydrolase
JHOFNEDM_02461 7.1e-308 ybiT S ABC transporter, ATP-binding protein
JHOFNEDM_02462 1.7e-221 S CAAX protease self-immunity
JHOFNEDM_02463 5.7e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
JHOFNEDM_02464 2.1e-102 speG J Acetyltransferase (GNAT) domain
JHOFNEDM_02465 8.8e-141 endA F DNA RNA non-specific endonuclease
JHOFNEDM_02466 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
JHOFNEDM_02467 1.1e-95 K Transcriptional regulator (TetR family)
JHOFNEDM_02468 1.6e-176 yhgE V domain protein
JHOFNEDM_02469 6.4e-08
JHOFNEDM_02471 7.4e-245 EGP Major facilitator Superfamily
JHOFNEDM_02472 0.0 mdlA V ABC transporter
JHOFNEDM_02473 0.0 mdlB V ABC transporter
JHOFNEDM_02475 6.3e-193 C Aldo/keto reductase family
JHOFNEDM_02476 9.7e-102 M Protein of unknown function (DUF3737)
JHOFNEDM_02477 1.3e-221 patB 4.4.1.8 E Aminotransferase, class I
JHOFNEDM_02478 3.9e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
JHOFNEDM_02479 1.5e-81
JHOFNEDM_02480 1.1e-124 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
JHOFNEDM_02481 5.8e-95 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
JHOFNEDM_02482 6.1e-76 T Belongs to the universal stress protein A family
JHOFNEDM_02483 5.7e-83 GM NAD(P)H-binding
JHOFNEDM_02484 1.3e-142 EGP Major Facilitator Superfamily
JHOFNEDM_02485 1.5e-142 akr5f 1.1.1.346 S reductase
JHOFNEDM_02486 1.3e-130 C Aldo keto reductase
JHOFNEDM_02487 2.5e-114 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JHOFNEDM_02488 8.2e-20 adhR K helix_turn_helix, mercury resistance
JHOFNEDM_02489 3e-25 fldA C Flavodoxin
JHOFNEDM_02491 2e-78 K Transcriptional regulator
JHOFNEDM_02492 5.6e-105 akr5f 1.1.1.346 S reductase
JHOFNEDM_02493 1.3e-87 GM NAD(P)H-binding
JHOFNEDM_02495 1.2e-70 glcU U sugar transport
JHOFNEDM_02496 3e-126 IQ reductase
JHOFNEDM_02497 2.5e-76 darA C Flavodoxin
JHOFNEDM_02498 1.3e-81 yiiE S Protein of unknown function (DUF1211)
JHOFNEDM_02499 1.1e-142 aRA11 1.1.1.346 S reductase
JHOFNEDM_02500 3.2e-150 IQ Enoyl-(Acyl carrier protein) reductase
JHOFNEDM_02501 2.3e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
JHOFNEDM_02502 1.2e-103 GM NAD(P)H-binding
JHOFNEDM_02503 2.8e-157 K LysR substrate binding domain
JHOFNEDM_02504 8.4e-60 S Domain of unknown function (DUF4440)
JHOFNEDM_02505 1.2e-112 pgm8 G Histidine phosphatase superfamily (branch 1)
JHOFNEDM_02506 8.2e-48
JHOFNEDM_02507 7e-37
JHOFNEDM_02508 7.3e-86 yvbK 3.1.3.25 K GNAT family
JHOFNEDM_02509 2.4e-83
JHOFNEDM_02510 2.7e-114 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JHOFNEDM_02511 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
JHOFNEDM_02512 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JHOFNEDM_02514 3.7e-120 macB V ABC transporter, ATP-binding protein
JHOFNEDM_02515 0.0 ylbB V ABC transporter permease
JHOFNEDM_02516 2.3e-237 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
JHOFNEDM_02517 1.7e-78 K transcriptional regulator, MerR family
JHOFNEDM_02518 1.3e-52 yphH S Cupin domain
JHOFNEDM_02519 5.6e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
JHOFNEDM_02520 1.1e-116 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JHOFNEDM_02521 4.7e-211 natB CP ABC-2 family transporter protein
JHOFNEDM_02522 3.6e-168 natA S ABC transporter, ATP-binding protein
JHOFNEDM_02523 5.2e-92 ogt 2.1.1.63 L Methyltransferase
JHOFNEDM_02524 1.2e-52 lytE M LysM domain
JHOFNEDM_02526 1.8e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
JHOFNEDM_02527 2.4e-297 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
JHOFNEDM_02528 3.7e-151 rlrG K Transcriptional regulator
JHOFNEDM_02529 9.3e-173 S Conserved hypothetical protein 698
JHOFNEDM_02530 2.1e-102 rimL J Acetyltransferase (GNAT) domain
JHOFNEDM_02531 1.4e-76 S Domain of unknown function (DUF4811)
JHOFNEDM_02532 2.4e-270 lmrB EGP Major facilitator Superfamily
JHOFNEDM_02533 1.9e-126 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
JHOFNEDM_02534 1.2e-179 ynfM EGP Major facilitator Superfamily
JHOFNEDM_02535 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
JHOFNEDM_02536 1.2e-155 mleP3 S Membrane transport protein
JHOFNEDM_02537 4.9e-109 S Membrane
JHOFNEDM_02538 4.1e-188 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JHOFNEDM_02539 8.1e-99 1.5.1.3 H RibD C-terminal domain
JHOFNEDM_02540 1.4e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
JHOFNEDM_02541 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
JHOFNEDM_02542 2.1e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
JHOFNEDM_02543 5.2e-174 hrtB V ABC transporter permease
JHOFNEDM_02544 6.6e-95 S Protein of unknown function (DUF1440)
JHOFNEDM_02545 8.5e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JHOFNEDM_02546 6.4e-148 KT helix_turn_helix, mercury resistance
JHOFNEDM_02547 1.6e-115 S Protein of unknown function (DUF554)
JHOFNEDM_02548 1.1e-92 yueI S Protein of unknown function (DUF1694)
JHOFNEDM_02549 2e-143 yvpB S Peptidase_C39 like family
JHOFNEDM_02550 4e-152 M Glycosyl hydrolases family 25
JHOFNEDM_02551 1e-111
JHOFNEDM_02552 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JHOFNEDM_02553 1.8e-84 hmpT S Pfam:DUF3816
JHOFNEDM_02554 1.1e-56 K helix_turn_helix multiple antibiotic resistance protein
JHOFNEDM_02555 7e-62 M domain protein
JHOFNEDM_02556 2.1e-25 S COG0463 Glycosyltransferases involved in cell wall biogenesis
JHOFNEDM_02557 3.8e-31 ymbI L Transposase and inactivated derivatives
JHOFNEDM_02558 5.7e-191 L PFAM Integrase, catalytic core
JHOFNEDM_02559 8e-24 tnpR1 L Resolvase, N terminal domain
JHOFNEDM_02560 5.3e-175 L Integrase core domain
JHOFNEDM_02562 1.9e-12 L Phage integrase, N-terminal SAM-like domain
JHOFNEDM_02563 2.2e-39 L Pfam:Integrase_AP2
JHOFNEDM_02564 4.4e-139 f42a O Band 7 protein
JHOFNEDM_02565 5.6e-303 norB EGP Major Facilitator
JHOFNEDM_02566 6.8e-93 K transcriptional regulator
JHOFNEDM_02567 6.5e-193 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JHOFNEDM_02568 4.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
JHOFNEDM_02569 2.7e-160 K LysR substrate binding domain
JHOFNEDM_02570 1.3e-123 S Protein of unknown function (DUF554)
JHOFNEDM_02571 2.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
JHOFNEDM_02572 1.3e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
JHOFNEDM_02573 8.8e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
JHOFNEDM_02574 3.5e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JHOFNEDM_02575 2.1e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
JHOFNEDM_02576 1.2e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
JHOFNEDM_02577 5.9e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JHOFNEDM_02578 2.1e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JHOFNEDM_02579 1.2e-126 IQ reductase
JHOFNEDM_02580 2e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
JHOFNEDM_02581 3.8e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JHOFNEDM_02582 7.7e-180 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JHOFNEDM_02583 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JHOFNEDM_02584 3.8e-179 yneE K Transcriptional regulator
JHOFNEDM_02585 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JHOFNEDM_02586 2.7e-58 S Protein of unknown function (DUF1648)
JHOFNEDM_02587 3.3e-197 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
JHOFNEDM_02588 2.9e-215 3.5.1.47 E Peptidase family M20/M25/M40
JHOFNEDM_02589 4.4e-217 E glutamate:sodium symporter activity
JHOFNEDM_02590 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
JHOFNEDM_02591 2.6e-177 1.6.5.5 C Zinc-binding dehydrogenase
JHOFNEDM_02592 1.5e-97 entB 3.5.1.19 Q Isochorismatase family
JHOFNEDM_02593 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JHOFNEDM_02594 2.3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JHOFNEDM_02595 3.8e-108 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
JHOFNEDM_02596 2.4e-123 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
JHOFNEDM_02597 5.9e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JHOFNEDM_02598 5.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
JHOFNEDM_02599 2.9e-268 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
JHOFNEDM_02601 8.1e-272 XK27_00765
JHOFNEDM_02602 3.9e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
JHOFNEDM_02603 1.4e-86
JHOFNEDM_02604 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
JHOFNEDM_02605 1.4e-50
JHOFNEDM_02606 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JHOFNEDM_02607 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JHOFNEDM_02608 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JHOFNEDM_02609 2.6e-39 ylqC S Belongs to the UPF0109 family
JHOFNEDM_02610 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JHOFNEDM_02611 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JHOFNEDM_02612 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JHOFNEDM_02613 6.6e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JHOFNEDM_02614 0.0 smc D Required for chromosome condensation and partitioning
JHOFNEDM_02615 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JHOFNEDM_02616 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JHOFNEDM_02617 6.7e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JHOFNEDM_02618 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JHOFNEDM_02619 0.0 yloV S DAK2 domain fusion protein YloV
JHOFNEDM_02620 1.8e-57 asp S Asp23 family, cell envelope-related function
JHOFNEDM_02621 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JHOFNEDM_02622 5.8e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
JHOFNEDM_02623 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JHOFNEDM_02624 1.6e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JHOFNEDM_02625 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
JHOFNEDM_02626 1.7e-134 stp 3.1.3.16 T phosphatase
JHOFNEDM_02627 1.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JHOFNEDM_02628 4.2e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JHOFNEDM_02629 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JHOFNEDM_02630 4e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JHOFNEDM_02631 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
JHOFNEDM_02632 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JHOFNEDM_02633 1.7e-54
JHOFNEDM_02634 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
JHOFNEDM_02635 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JHOFNEDM_02636 1.2e-104 opuCB E ABC transporter permease
JHOFNEDM_02637 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
JHOFNEDM_02638 6.3e-307 recN L May be involved in recombinational repair of damaged DNA
JHOFNEDM_02639 7.4e-77 argR K Regulates arginine biosynthesis genes
JHOFNEDM_02640 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
JHOFNEDM_02641 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JHOFNEDM_02642 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JHOFNEDM_02643 1.6e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JHOFNEDM_02644 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JHOFNEDM_02645 1.7e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JHOFNEDM_02646 1.7e-73 yqhY S Asp23 family, cell envelope-related function
JHOFNEDM_02647 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JHOFNEDM_02648 5.9e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
JHOFNEDM_02649 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JHOFNEDM_02650 3.2e-53 ysxB J Cysteine protease Prp
JHOFNEDM_02651 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
JHOFNEDM_02652 5.2e-89 K Transcriptional regulator
JHOFNEDM_02653 5.4e-19
JHOFNEDM_02657 1.7e-30
JHOFNEDM_02658 9.1e-56
JHOFNEDM_02659 3.1e-98 dut S Protein conserved in bacteria
JHOFNEDM_02660 4e-181
JHOFNEDM_02661 2.5e-161
JHOFNEDM_02662 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
JHOFNEDM_02663 4.6e-64 glnR K Transcriptional regulator
JHOFNEDM_02664 2.4e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JHOFNEDM_02665 2.2e-139 glpQ 3.1.4.46 C phosphodiesterase
JHOFNEDM_02666 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
JHOFNEDM_02667 4.4e-68 yqhL P Rhodanese-like protein
JHOFNEDM_02668 1.9e-110 pepE 3.4.13.21 E Belongs to the peptidase S51 family
JHOFNEDM_02669 5.7e-180 glk 2.7.1.2 G Glucokinase
JHOFNEDM_02670 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
JHOFNEDM_02671 1e-114 gluP 3.4.21.105 S Peptidase, S54 family
JHOFNEDM_02672 2.8e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JHOFNEDM_02673 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JHOFNEDM_02674 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
JHOFNEDM_02675 0.0 S membrane
JHOFNEDM_02676 1.5e-54 yneR S Belongs to the HesB IscA family
JHOFNEDM_02677 4e-75 XK27_02470 K LytTr DNA-binding domain
JHOFNEDM_02678 2.3e-96 liaI S membrane
JHOFNEDM_02679 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JHOFNEDM_02680 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
JHOFNEDM_02681 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JHOFNEDM_02682 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JHOFNEDM_02683 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JHOFNEDM_02684 7.4e-64 yodB K Transcriptional regulator, HxlR family
JHOFNEDM_02685 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
JHOFNEDM_02686 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHOFNEDM_02687 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JHOFNEDM_02688 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JHOFNEDM_02689 3.9e-99 S SdpI/YhfL protein family
JHOFNEDM_02690 4.5e-227 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JHOFNEDM_02691 0.0 sbcC L Putative exonuclease SbcCD, C subunit
JHOFNEDM_02692 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
JHOFNEDM_02693 5.2e-306 arlS 2.7.13.3 T Histidine kinase
JHOFNEDM_02694 4.3e-121 K response regulator
JHOFNEDM_02695 4.2e-245 rarA L recombination factor protein RarA
JHOFNEDM_02696 3e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JHOFNEDM_02697 1e-168 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JHOFNEDM_02698 2.2e-89 S Peptidase propeptide and YPEB domain
JHOFNEDM_02699 1.6e-97 yceD S Uncharacterized ACR, COG1399
JHOFNEDM_02700 4.9e-218 ylbM S Belongs to the UPF0348 family
JHOFNEDM_02701 5.8e-140 yqeM Q Methyltransferase
JHOFNEDM_02702 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JHOFNEDM_02703 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
JHOFNEDM_02704 7e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JHOFNEDM_02705 1.1e-50 yhbY J RNA-binding protein
JHOFNEDM_02706 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
JHOFNEDM_02707 1.4e-98 yqeG S HAD phosphatase, family IIIA
JHOFNEDM_02708 2.9e-79
JHOFNEDM_02709 1e-248 pgaC GT2 M Glycosyl transferase
JHOFNEDM_02710 1.5e-135 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
JHOFNEDM_02711 1e-62 hxlR K Transcriptional regulator, HxlR family
JHOFNEDM_02712 1.3e-60 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
JHOFNEDM_02713 6.4e-122 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
JHOFNEDM_02714 3.6e-238 yrvN L AAA C-terminal domain
JHOFNEDM_02715 9.9e-57
JHOFNEDM_02716 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JHOFNEDM_02717 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JHOFNEDM_02718 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JHOFNEDM_02719 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JHOFNEDM_02720 2.1e-171 dnaI L Primosomal protein DnaI
JHOFNEDM_02721 1.1e-248 dnaB L replication initiation and membrane attachment
JHOFNEDM_02722 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JHOFNEDM_02723 3e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JHOFNEDM_02724 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JHOFNEDM_02725 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHOFNEDM_02726 4.5e-121 ybhL S Belongs to the BI1 family
JHOFNEDM_02727 2.3e-111 hipB K Helix-turn-helix
JHOFNEDM_02728 5.5e-45 yitW S Iron-sulfur cluster assembly protein
JHOFNEDM_02729 1.4e-272 sufB O assembly protein SufB
JHOFNEDM_02730 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
JHOFNEDM_02731 8.9e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JHOFNEDM_02732 8.4e-243 sufD O FeS assembly protein SufD
JHOFNEDM_02733 4.2e-144 sufC O FeS assembly ATPase SufC
JHOFNEDM_02734 1.3e-34 feoA P FeoA domain
JHOFNEDM_02735 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
JHOFNEDM_02736 7.9e-21 S Virus attachment protein p12 family
JHOFNEDM_02737 9.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JHOFNEDM_02738 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
JHOFNEDM_02739 1.5e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JHOFNEDM_02740 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
JHOFNEDM_02741 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JHOFNEDM_02742 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
JHOFNEDM_02743 4.8e-224 ecsB U ABC transporter
JHOFNEDM_02744 1.6e-134 ecsA V ABC transporter, ATP-binding protein
JHOFNEDM_02745 9.9e-82 hit FG histidine triad
JHOFNEDM_02746 3.5e-39
JHOFNEDM_02747 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JHOFNEDM_02748 3.5e-78 S WxL domain surface cell wall-binding
JHOFNEDM_02749 2e-102 S WxL domain surface cell wall-binding
JHOFNEDM_02750 1.4e-192 S Fn3-like domain
JHOFNEDM_02751 7.9e-61
JHOFNEDM_02752 0.0
JHOFNEDM_02753 9.4e-242 npr 1.11.1.1 C NADH oxidase
JHOFNEDM_02754 3.3e-112 K Bacterial regulatory proteins, tetR family
JHOFNEDM_02755 5.1e-116 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
JHOFNEDM_02756 1.4e-106
JHOFNEDM_02757 9.3e-106 GBS0088 S Nucleotidyltransferase
JHOFNEDM_02758 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
JHOFNEDM_02759 6.9e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
JHOFNEDM_02760 1.8e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
JHOFNEDM_02761 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHOFNEDM_02762 0.0 S membrane
JHOFNEDM_02763 4.8e-67 S NUDIX domain
JHOFNEDM_02764 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JHOFNEDM_02765 8.9e-184 ykoT GT2 M Glycosyl transferase family 2
JHOFNEDM_02766 1e-268 mutS L MutS domain V
JHOFNEDM_02767 1e-271 mutS L ATPase domain of DNA mismatch repair MUTS family
JHOFNEDM_02768 1e-200 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JHOFNEDM_02769 7.5e-227 3.6.3.6 P Cation transporter/ATPase, N-terminus
JHOFNEDM_02770 4.8e-127 3.6.3.6 P Cation transporter/ATPase, N-terminus
JHOFNEDM_02771 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
JHOFNEDM_02772 0.0 copB 3.6.3.4 P P-type ATPase
JHOFNEDM_02773 9.4e-74 copR K Copper transport repressor CopY TcrY
JHOFNEDM_02774 7.4e-40
JHOFNEDM_02775 7.7e-73 S COG NOG18757 non supervised orthologous group
JHOFNEDM_02776 2.5e-248 lmrB EGP Major facilitator Superfamily
JHOFNEDM_02777 3.4e-25
JHOFNEDM_02778 4.2e-49
JHOFNEDM_02779 9.4e-65 ycgX S Protein of unknown function (DUF1398)
JHOFNEDM_02780 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
JHOFNEDM_02781 7.7e-214 mdtG EGP Major facilitator Superfamily
JHOFNEDM_02782 6.8e-181 D Alpha beta
JHOFNEDM_02783 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
JHOFNEDM_02784 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
JHOFNEDM_02785 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
JHOFNEDM_02786 8.6e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JHOFNEDM_02787 3.8e-152 ywkB S Membrane transport protein
JHOFNEDM_02788 5.2e-164 yvgN C Aldo keto reductase
JHOFNEDM_02789 9.2e-133 thrE S Putative threonine/serine exporter
JHOFNEDM_02790 2e-77 S Threonine/Serine exporter, ThrE
JHOFNEDM_02791 2.3e-43 S Protein of unknown function (DUF1093)
JHOFNEDM_02792 1.5e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JHOFNEDM_02793 1.9e-89 ymdB S Macro domain protein
JHOFNEDM_02794 1.2e-95 K transcriptional regulator
JHOFNEDM_02795 5.5e-50 yvlA
JHOFNEDM_02796 7.9e-161 ypuA S Protein of unknown function (DUF1002)
JHOFNEDM_02797 0.0
JHOFNEDM_02798 1.5e-186 S Bacterial protein of unknown function (DUF916)
JHOFNEDM_02799 1.7e-129 S WxL domain surface cell wall-binding
JHOFNEDM_02800 1.5e-135 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
JHOFNEDM_02801 1.2e-88 K Winged helix DNA-binding domain
JHOFNEDM_02802 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
JHOFNEDM_02803 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
JHOFNEDM_02804 1.8e-27
JHOFNEDM_02805 1.6e-284 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
JHOFNEDM_02806 1.5e-75 mltD CBM50 M PFAM NLP P60 protein
JHOFNEDM_02807 1.1e-53
JHOFNEDM_02808 2.1e-61
JHOFNEDM_02810 8.1e-108
JHOFNEDM_02811 2.5e-52 S Uncharacterized protein conserved in bacteria (DUF2316)
JHOFNEDM_02812 2.6e-159 4.1.1.46 S Amidohydrolase
JHOFNEDM_02813 6.7e-99 K transcriptional regulator
JHOFNEDM_02814 2.1e-182 yfeX P Peroxidase
JHOFNEDM_02815 4.9e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
JHOFNEDM_02816 2.4e-127 ydcF S Gram-negative-bacterium-type cell wall biogenesis
JHOFNEDM_02817 6.9e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
JHOFNEDM_02818 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
JHOFNEDM_02819 9.8e-143 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
JHOFNEDM_02820 1.5e-55 txlA O Thioredoxin-like domain
JHOFNEDM_02821 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
JHOFNEDM_02822 1.6e-18
JHOFNEDM_02823 2.8e-94 dps P Belongs to the Dps family
JHOFNEDM_02824 1.6e-32 copZ P Heavy-metal-associated domain
JHOFNEDM_02825 4.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
JHOFNEDM_02826 0.0 pepO 3.4.24.71 O Peptidase family M13
JHOFNEDM_02827 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JHOFNEDM_02828 3.8e-262 nox C NADH oxidase
JHOFNEDM_02829 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
JHOFNEDM_02830 6.1e-164 S Cell surface protein
JHOFNEDM_02831 1.5e-118 S WxL domain surface cell wall-binding
JHOFNEDM_02832 2.3e-99 S WxL domain surface cell wall-binding
JHOFNEDM_02833 4.6e-45
JHOFNEDM_02834 2.7e-103 K Bacterial regulatory proteins, tetR family
JHOFNEDM_02835 1.5e-49
JHOFNEDM_02836 1.4e-248 S Putative metallopeptidase domain
JHOFNEDM_02837 7.8e-219 3.1.3.1 S associated with various cellular activities
JHOFNEDM_02838 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
JHOFNEDM_02839 0.0 ubiB S ABC1 family
JHOFNEDM_02840 4.5e-250 brnQ U Component of the transport system for branched-chain amino acids
JHOFNEDM_02841 0.0 lacS G Transporter
JHOFNEDM_02842 0.0 lacA 3.2.1.23 G -beta-galactosidase
JHOFNEDM_02843 1.6e-188 lacR K Transcriptional regulator
JHOFNEDM_02844 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
JHOFNEDM_02845 3.6e-230 mdtH P Sugar (and other) transporter
JHOFNEDM_02846 2.3e-303 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
JHOFNEDM_02847 8.6e-232 EGP Major facilitator Superfamily
JHOFNEDM_02848 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
JHOFNEDM_02849 5e-100 fic D Fic/DOC family
JHOFNEDM_02850 1.6e-76 K Helix-turn-helix XRE-family like proteins
JHOFNEDM_02851 2e-183 galR K Transcriptional regulator
JHOFNEDM_02852 1.3e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JHOFNEDM_02853 8.9e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JHOFNEDM_02854 9.3e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JHOFNEDM_02855 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
JHOFNEDM_02856 7e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
JHOFNEDM_02857 0.0 rafA 3.2.1.22 G alpha-galactosidase
JHOFNEDM_02858 0.0 lacS G Transporter
JHOFNEDM_02859 4.1e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JHOFNEDM_02860 7e-173 galR K Transcriptional regulator
JHOFNEDM_02861 2.2e-193 C Aldo keto reductase family protein
JHOFNEDM_02862 3.1e-65 S pyridoxamine 5-phosphate
JHOFNEDM_02863 0.0 1.3.5.4 C FAD binding domain
JHOFNEDM_02864 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JHOFNEDM_02865 2.4e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JHOFNEDM_02866 2.5e-166 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JHOFNEDM_02867 1e-173 K Transcriptional regulator, LysR family
JHOFNEDM_02868 1.2e-219 ydiN EGP Major Facilitator Superfamily
JHOFNEDM_02869 5e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JHOFNEDM_02870 9.4e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JHOFNEDM_02871 3e-156 IQ Enoyl-(Acyl carrier protein) reductase
JHOFNEDM_02872 2.3e-164 G Xylose isomerase-like TIM barrel
JHOFNEDM_02873 4.7e-168 K Transcriptional regulator, LysR family
JHOFNEDM_02874 1.2e-201 EGP Major Facilitator Superfamily
JHOFNEDM_02875 7.6e-64
JHOFNEDM_02876 1.8e-155 estA S Putative esterase
JHOFNEDM_02877 1.2e-134 K UTRA domain
JHOFNEDM_02878 3.6e-249 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHOFNEDM_02879 8.8e-165 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JHOFNEDM_02880 7.6e-158 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
JHOFNEDM_02881 1.1e-211 S Bacterial protein of unknown function (DUF871)
JHOFNEDM_02882 5.5e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHOFNEDM_02883 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
JHOFNEDM_02884 3.6e-154 licT K CAT RNA binding domain
JHOFNEDM_02885 0.0 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JHOFNEDM_02886 3.2e-225 malY 4.4.1.8 E Aminotransferase class I and II
JHOFNEDM_02887 2.6e-147 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
JHOFNEDM_02888 9e-69 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
JHOFNEDM_02889 3.3e-74 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JHOFNEDM_02890 3.7e-79 ptsG 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
JHOFNEDM_02891 1.3e-137 yleF K Helix-turn-helix domain, rpiR family
JHOFNEDM_02892 7.2e-246 sacX 2.7.1.193, 2.7.1.211 G phosphotransferase system
JHOFNEDM_02893 5.4e-156 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JHOFNEDM_02894 1.8e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
JHOFNEDM_02895 3.1e-294 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHOFNEDM_02896 2.7e-290 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHOFNEDM_02897 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
JHOFNEDM_02898 3.8e-159 licT K CAT RNA binding domain
JHOFNEDM_02899 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
JHOFNEDM_02900 1.1e-173 K Transcriptional regulator, LacI family
JHOFNEDM_02901 8.8e-270 G Major Facilitator
JHOFNEDM_02902 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
JHOFNEDM_02904 1.3e-174 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
JHOFNEDM_02905 3e-145 yxeH S hydrolase
JHOFNEDM_02906 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JHOFNEDM_02907 7e-113 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JHOFNEDM_02908 3.2e-240 ulaA 2.7.1.194 S PTS system sugar-specific permease component
JHOFNEDM_02909 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
JHOFNEDM_02910 2e-77 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JHOFNEDM_02911 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JHOFNEDM_02912 1.3e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
JHOFNEDM_02913 2.5e-187 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
JHOFNEDM_02914 1.1e-231 gatC G PTS system sugar-specific permease component
JHOFNEDM_02915 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
JHOFNEDM_02916 3.3e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JHOFNEDM_02917 5.2e-123 K DeoR C terminal sensor domain
JHOFNEDM_02918 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
JHOFNEDM_02919 2.6e-70 yueI S Protein of unknown function (DUF1694)
JHOFNEDM_02920 9.6e-103 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
JHOFNEDM_02921 7.8e-266 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
JHOFNEDM_02922 1e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
JHOFNEDM_02923 3e-306 araB 2.7.1.12, 2.7.1.16, 2.7.1.5 G carbohydrate kinase FGGY
JHOFNEDM_02924 1.6e-255 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
JHOFNEDM_02925 3.1e-206 araR K Transcriptional regulator
JHOFNEDM_02926 6.7e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JHOFNEDM_02927 4.2e-228 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
JHOFNEDM_02928 4.2e-70 S Pyrimidine dimer DNA glycosylase
JHOFNEDM_02929 4.5e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
JHOFNEDM_02930 3.6e-11
JHOFNEDM_02931 9e-13 ytgB S Transglycosylase associated protein
JHOFNEDM_02932 1.6e-290 katA 1.11.1.6 C Belongs to the catalase family
JHOFNEDM_02933 4.9e-78 yneH 1.20.4.1 K ArsC family
JHOFNEDM_02934 2.8e-134 K LytTr DNA-binding domain
JHOFNEDM_02935 8.7e-160 2.7.13.3 T GHKL domain
JHOFNEDM_02936 1.8e-12
JHOFNEDM_02937 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
JHOFNEDM_02938 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
JHOFNEDM_02940 6.1e-202 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
JHOFNEDM_02941 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JHOFNEDM_02942 8.7e-72 K Transcriptional regulator
JHOFNEDM_02943 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JHOFNEDM_02944 1.1e-71 yueI S Protein of unknown function (DUF1694)
JHOFNEDM_02945 1e-125 S Membrane
JHOFNEDM_02946 1.3e-164 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
JHOFNEDM_02947 1.3e-256 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
JHOFNEDM_02948 5e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
JHOFNEDM_02949 3.4e-285 rhaB 2.7.1.12, 2.7.1.16, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
JHOFNEDM_02950 7.8e-244 iolF EGP Major facilitator Superfamily
JHOFNEDM_02951 7.1e-178 rhaR K helix_turn_helix, arabinose operon control protein
JHOFNEDM_02952 1e-139 K DeoR C terminal sensor domain
JHOFNEDM_02958 5.1e-08
JHOFNEDM_02964 1.4e-90 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
JHOFNEDM_02965 1.8e-182 P secondary active sulfate transmembrane transporter activity
JHOFNEDM_02966 5.8e-94
JHOFNEDM_02967 1.7e-93 K Acetyltransferase (GNAT) domain
JHOFNEDM_02968 1.1e-155 T Calcineurin-like phosphoesterase superfamily domain
JHOFNEDM_02970 5.2e-232 mntH P H( )-stimulated, divalent metal cation uptake system
JHOFNEDM_02971 7.6e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JHOFNEDM_02972 3e-254 mmuP E amino acid
JHOFNEDM_02973 1.7e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
JHOFNEDM_02974 9.3e-294 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
JHOFNEDM_02975 3.1e-122
JHOFNEDM_02976 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JHOFNEDM_02977 1.4e-278 bmr3 EGP Major facilitator Superfamily
JHOFNEDM_02978 4.1e-139 N Cell shape-determining protein MreB
JHOFNEDM_02979 0.0 S Pfam Methyltransferase
JHOFNEDM_02980 6.7e-268 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
JHOFNEDM_02981 1.8e-297 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
JHOFNEDM_02982 4.2e-29
JHOFNEDM_02983 7.7e-94 ytqB 2.1.1.176 J Putative rRNA methylase
JHOFNEDM_02984 1.5e-123 3.6.1.27 I Acid phosphatase homologues
JHOFNEDM_02985 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JHOFNEDM_02986 3e-301 ytgP S Polysaccharide biosynthesis protein
JHOFNEDM_02987 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JHOFNEDM_02988 3.7e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JHOFNEDM_02989 1.3e-273 pepV 3.5.1.18 E dipeptidase PepV
JHOFNEDM_02990 4.1e-84 uspA T Belongs to the universal stress protein A family
JHOFNEDM_02991 5.2e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
JHOFNEDM_02992 1.5e-172 ugpA U Binding-protein-dependent transport system inner membrane component
JHOFNEDM_02993 1.1e-150 ugpE G ABC transporter permease
JHOFNEDM_02994 6.4e-262 ugpB G Bacterial extracellular solute-binding protein
JHOFNEDM_02995 3.8e-125 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JHOFNEDM_02996 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
JHOFNEDM_02997 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JHOFNEDM_02998 1.5e-178 XK27_06930 V domain protein
JHOFNEDM_03000 1.2e-124 V Transport permease protein
JHOFNEDM_03001 2.3e-156 V ABC transporter
JHOFNEDM_03002 4e-176 K LytTr DNA-binding domain
JHOFNEDM_03003 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHOFNEDM_03004 1.6e-64 K helix_turn_helix, mercury resistance
JHOFNEDM_03005 8.8e-113 GM NAD(P)H-binding
JHOFNEDM_03006 9.3e-159 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JHOFNEDM_03007 2.9e-148 S Sucrose-6F-phosphate phosphohydrolase
JHOFNEDM_03008 1.7e-108
JHOFNEDM_03009 2.2e-224 pltK 2.7.13.3 T GHKL domain
JHOFNEDM_03010 1.6e-137 pltR K LytTr DNA-binding domain
JHOFNEDM_03011 4.5e-55
JHOFNEDM_03012 2.5e-59
JHOFNEDM_03013 8.7e-114 S CAAX protease self-immunity
JHOFNEDM_03014 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
JHOFNEDM_03015 1e-90
JHOFNEDM_03016 2.5e-46
JHOFNEDM_03017 0.0 uvrA2 L ABC transporter
JHOFNEDM_03019 2.6e-211 L Belongs to the 'phage' integrase family
JHOFNEDM_03026 1.5e-36 S Pfam:Peptidase_M78
JHOFNEDM_03027 8e-25 ps115 K Helix-turn-helix XRE-family like proteins
JHOFNEDM_03029 1.3e-62 S ORF6C domain
JHOFNEDM_03031 1.3e-06
JHOFNEDM_03032 8.9e-56 S Domain of unknown function (DUF771)
JHOFNEDM_03037 2.1e-58 S Putative HNHc nuclease
JHOFNEDM_03038 1.6e-38 S Putative HNHc nuclease
JHOFNEDM_03039 3.6e-71 L DnaD domain protein
JHOFNEDM_03040 2.4e-144 pi346 L IstB-like ATP binding protein
JHOFNEDM_03042 7.8e-46
JHOFNEDM_03043 4.1e-17
JHOFNEDM_03045 8.2e-26 S YopX protein
JHOFNEDM_03047 1.4e-17
JHOFNEDM_03048 4.3e-64 S Transcriptional regulator, RinA family
JHOFNEDM_03050 8.6e-13
JHOFNEDM_03051 6.4e-69 L HNH nucleases
JHOFNEDM_03052 5.2e-29 S HNH endonuclease
JHOFNEDM_03053 1.4e-78 L Phage terminase, small subunit
JHOFNEDM_03054 0.0 S Phage Terminase
JHOFNEDM_03055 1.1e-24 S Protein of unknown function (DUF1056)
JHOFNEDM_03056 6.2e-224 S Phage portal protein
JHOFNEDM_03057 8.4e-126 S Clp protease
JHOFNEDM_03058 2.6e-209 S Phage capsid family
JHOFNEDM_03059 3.6e-52 S Phage gp6-like head-tail connector protein
JHOFNEDM_03060 1.4e-25 S Phage head-tail joining protein
JHOFNEDM_03061 9.1e-40
JHOFNEDM_03062 5.9e-27
JHOFNEDM_03063 1e-71 S Phage tail tube protein
JHOFNEDM_03066 0.0 S peptidoglycan catabolic process
JHOFNEDM_03067 1.3e-225 S Phage tail protein
JHOFNEDM_03068 5.1e-294 S Phage minor structural protein
JHOFNEDM_03069 2.4e-160
JHOFNEDM_03072 4.5e-53
JHOFNEDM_03073 3.7e-177 3.5.1.28 M Glycosyl hydrolases family 25
JHOFNEDM_03074 5.3e-31 S Haemolysin XhlA
JHOFNEDM_03077 1.1e-53
JHOFNEDM_03078 3.5e-10
JHOFNEDM_03079 2.1e-180
JHOFNEDM_03080 1.9e-89 gtcA S Teichoic acid glycosylation protein
JHOFNEDM_03081 1.8e-57 S Protein of unknown function (DUF1516)
JHOFNEDM_03082 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
JHOFNEDM_03083 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JHOFNEDM_03084 6.1e-307 S Protein conserved in bacteria
JHOFNEDM_03085 9.7e-230 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
JHOFNEDM_03086 8.7e-113 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
JHOFNEDM_03087 3.7e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
JHOFNEDM_03088 1.8e-304 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
JHOFNEDM_03089 0.0 yfbS P Sodium:sulfate symporter transmembrane region
JHOFNEDM_03090 1.4e-243 dinF V MatE
JHOFNEDM_03091 1.9e-31
JHOFNEDM_03094 1.7e-78 elaA S Acetyltransferase (GNAT) domain
JHOFNEDM_03095 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
JHOFNEDM_03096 6.7e-81
JHOFNEDM_03097 0.0 yhcA V MacB-like periplasmic core domain
JHOFNEDM_03098 3.7e-106
JHOFNEDM_03099 0.0 K PRD domain
JHOFNEDM_03100 2.4e-62 S Domain of unknown function (DUF3284)
JHOFNEDM_03101 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
JHOFNEDM_03102 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
JHOFNEDM_03103 2.3e-219 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHOFNEDM_03104 6.1e-290 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHOFNEDM_03105 4.4e-147 EGP Major facilitator Superfamily
JHOFNEDM_03106 3.1e-56 EGP Major facilitator Superfamily
JHOFNEDM_03107 1e-113 M ErfK YbiS YcfS YnhG
JHOFNEDM_03108 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHOFNEDM_03109 8.4e-284 ydfD K Alanine-glyoxylate amino-transferase
JHOFNEDM_03110 4e-102 argO S LysE type translocator
JHOFNEDM_03111 1.9e-214 arcT 2.6.1.1 E Aminotransferase
JHOFNEDM_03112 4.4e-77 argR K Regulates arginine biosynthesis genes
JHOFNEDM_03113 2.9e-12
JHOFNEDM_03114 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JHOFNEDM_03115 1e-54 yheA S Belongs to the UPF0342 family
JHOFNEDM_03116 4.5e-230 yhaO L Ser Thr phosphatase family protein
JHOFNEDM_03117 0.0 L AAA domain
JHOFNEDM_03118 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
JHOFNEDM_03119 8.7e-215
JHOFNEDM_03120 5.2e-181 3.4.21.102 M Peptidase family S41
JHOFNEDM_03121 1.2e-177 K LysR substrate binding domain
JHOFNEDM_03122 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
JHOFNEDM_03123 0.0 1.3.5.4 C FAD binding domain
JHOFNEDM_03124 1.7e-99
JHOFNEDM_03125 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
JHOFNEDM_03126 8.4e-60 M domain protein
JHOFNEDM_03127 1.5e-22 M domain protein
JHOFNEDM_03128 6.4e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
JHOFNEDM_03129 3.9e-262 frdC 1.3.5.4 C FAD binding domain
JHOFNEDM_03130 3.6e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
JHOFNEDM_03131 4.9e-162 mleR K LysR family transcriptional regulator
JHOFNEDM_03132 1.7e-165 mleR K LysR family
JHOFNEDM_03133 3.6e-307 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
JHOFNEDM_03134 2e-164 mleP S Sodium Bile acid symporter family
JHOFNEDM_03135 5.8e-253 yfnA E Amino Acid
JHOFNEDM_03136 3e-99 S ECF transporter, substrate-specific component
JHOFNEDM_03137 5.3e-23
JHOFNEDM_03138 1.2e-283 S Alpha beta
JHOFNEDM_03139 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
JHOFNEDM_03140 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
JHOFNEDM_03141 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
JHOFNEDM_03142 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JHOFNEDM_03143 3.4e-156 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
JHOFNEDM_03144 1.5e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JHOFNEDM_03145 1.1e-164 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
JHOFNEDM_03146 8.7e-184 S Oxidoreductase family, NAD-binding Rossmann fold
JHOFNEDM_03147 2.6e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
JHOFNEDM_03148 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JHOFNEDM_03149 1e-93 S UPF0316 protein
JHOFNEDM_03150 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JHOFNEDM_03151 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JHOFNEDM_03152 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JHOFNEDM_03153 7.5e-198 camS S sex pheromone
JHOFNEDM_03154 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JHOFNEDM_03155 8.5e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JHOFNEDM_03156 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JHOFNEDM_03157 1e-190 yegS 2.7.1.107 G Lipid kinase
JHOFNEDM_03158 1.2e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JHOFNEDM_03159 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
JHOFNEDM_03160 0.0 yfgQ P E1-E2 ATPase
JHOFNEDM_03161 6.1e-241 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHOFNEDM_03162 1.3e-167 S Alpha/beta hydrolase of unknown function (DUF915)
JHOFNEDM_03163 2.3e-151 gntR K rpiR family
JHOFNEDM_03164 5.4e-144 lys M Glycosyl hydrolases family 25
JHOFNEDM_03165 1.1e-62 S Domain of unknown function (DUF4828)
JHOFNEDM_03166 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
JHOFNEDM_03167 2.4e-189 mocA S Oxidoreductase
JHOFNEDM_03168 7.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
JHOFNEDM_03170 2.3e-75 T Universal stress protein family
JHOFNEDM_03171 1.4e-245 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHOFNEDM_03172 1.8e-164 S Alpha/beta hydrolase of unknown function (DUF915)
JHOFNEDM_03174 1.3e-73
JHOFNEDM_03175 1.4e-106
JHOFNEDM_03176 2.9e-254 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
JHOFNEDM_03177 1.2e-219 pbpX1 V Beta-lactamase
JHOFNEDM_03178 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JHOFNEDM_03179 1.3e-157 yihY S Belongs to the UPF0761 family
JHOFNEDM_03180 3.7e-131 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
JHOFNEDM_03181 2e-15 L Transposase
JHOFNEDM_03182 1.8e-68 L Transposase
JHOFNEDM_03183 1.9e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
JHOFNEDM_03184 1.1e-50 gtcA S Teichoic acid glycosylation protein
JHOFNEDM_03185 2.3e-305
JHOFNEDM_03186 2.1e-112 cps3D
JHOFNEDM_03188 6.6e-168 cps3F
JHOFNEDM_03189 1.2e-136 rfbN GT2 S Glycosyltransferase like family 2
JHOFNEDM_03190 1.4e-78 S Glycosyl transferase family 2
JHOFNEDM_03191 8.5e-88 welB S Glycosyltransferase like family 2
JHOFNEDM_03192 2.2e-131 rgpB GT2 M Glycosyl transferase family 2
JHOFNEDM_03193 5.8e-147 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JHOFNEDM_03194 1.4e-120 1.1.1.133 S Glycosyltransferase like family 2
JHOFNEDM_03195 4.7e-138 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
JHOFNEDM_03196 2.5e-159 rfbJ M Glycosyl transferase family 2
JHOFNEDM_03197 6e-226 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
JHOFNEDM_03198 9.7e-106 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
JHOFNEDM_03199 1.4e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JHOFNEDM_03200 6e-149 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JHOFNEDM_03201 2.7e-92
JHOFNEDM_03202 5.6e-101 L Integrase
JHOFNEDM_03203 0.0 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JHOFNEDM_03204 9.6e-74 K helix_turn_helix multiple antibiotic resistance protein
JHOFNEDM_03205 8.3e-260 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
JHOFNEDM_03206 3.2e-121 rfbP M Bacterial sugar transferase
JHOFNEDM_03207 3.8e-53
JHOFNEDM_03208 7.3e-33 S Protein of unknown function (DUF2922)
JHOFNEDM_03209 7e-30
JHOFNEDM_03210 6.2e-25
JHOFNEDM_03211 1.5e-100 K DNA-templated transcription, initiation
JHOFNEDM_03212 3.9e-125
JHOFNEDM_03213 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
JHOFNEDM_03214 4.1e-106 ygaC J Belongs to the UPF0374 family
JHOFNEDM_03215 4e-133 cwlO M NlpC/P60 family
JHOFNEDM_03216 7.8e-48 K sequence-specific DNA binding
JHOFNEDM_03217 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
JHOFNEDM_03218 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
JHOFNEDM_03219 9.3e-188 yueF S AI-2E family transporter
JHOFNEDM_03220 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
JHOFNEDM_03221 1.6e-212 gntP EG Gluconate
JHOFNEDM_03222 4.6e-293 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
JHOFNEDM_03223 3.6e-168 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
JHOFNEDM_03224 2.8e-254 gor 1.8.1.7 C Glutathione reductase
JHOFNEDM_03225 1.7e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JHOFNEDM_03226 2.5e-272
JHOFNEDM_03227 6.5e-198 M MucBP domain
JHOFNEDM_03228 7.1e-161 lysR5 K LysR substrate binding domain
JHOFNEDM_03229 5.5e-126 yxaA S membrane transporter protein
JHOFNEDM_03230 3.2e-57 ywjH S Protein of unknown function (DUF1634)
JHOFNEDM_03231 1.3e-309 oppA E ABC transporter, substratebinding protein
JHOFNEDM_03232 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHOFNEDM_03233 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHOFNEDM_03234 9.2e-203 oppD P Belongs to the ABC transporter superfamily
JHOFNEDM_03235 1.8e-181 oppF P Belongs to the ABC transporter superfamily
JHOFNEDM_03236 1e-63 K Winged helix DNA-binding domain
JHOFNEDM_03237 1.6e-102 L Integrase
JHOFNEDM_03238 0.0 clpE O Belongs to the ClpA ClpB family
JHOFNEDM_03239 6.5e-30
JHOFNEDM_03240 2.7e-39 ptsH G phosphocarrier protein HPR
JHOFNEDM_03241 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JHOFNEDM_03242 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
JHOFNEDM_03243 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
JHOFNEDM_03244 9.7e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JHOFNEDM_03245 1.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JHOFNEDM_03246 1.8e-228 patA 2.6.1.1 E Aminotransferase
JHOFNEDM_03247 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
JHOFNEDM_03248 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)