ORF_ID e_value Gene_name EC_number CAZy COGs Description
KDIFEGBE_00001 4.1e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KDIFEGBE_00002 3.4e-14 rpmH J Ribosomal protein L34
KDIFEGBE_00003 1.3e-99 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
KDIFEGBE_00004 6e-103 K Transcriptional regulator
KDIFEGBE_00005 1e-150 jag S RNA-binding protein
KDIFEGBE_00006 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KDIFEGBE_00007 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KDIFEGBE_00008 3.3e-269 argH 4.3.2.1 E Argininosuccinate lyase
KDIFEGBE_00009 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KDIFEGBE_00010 1.8e-128 fasA KT Response regulator of the LytR AlgR family
KDIFEGBE_00011 8e-225 fasC 2.7.13.3 T protein histidine kinase activity
KDIFEGBE_00012 1.9e-207 hpk9 2.7.13.3 T protein histidine kinase activity
KDIFEGBE_00013 1.2e-150 hpk9 2.7.13.3 T protein histidine kinase activity
KDIFEGBE_00014 1.4e-229 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KDIFEGBE_00015 1.8e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KDIFEGBE_00016 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KDIFEGBE_00017 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KDIFEGBE_00018 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KDIFEGBE_00019 1.2e-50 S Protein of unknown function (DUF3397)
KDIFEGBE_00020 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KDIFEGBE_00021 7e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
KDIFEGBE_00022 1.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KDIFEGBE_00023 9.3e-76 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
KDIFEGBE_00024 2.7e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KDIFEGBE_00025 1.8e-107 XK27_09620 S FMN reductase (NADPH) activity
KDIFEGBE_00026 7.9e-230 XK27_09615 C reductase
KDIFEGBE_00027 8.2e-140 fnt P Formate nitrite transporter
KDIFEGBE_00028 6.7e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
KDIFEGBE_00029 9.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KDIFEGBE_00030 1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KDIFEGBE_00031 2.4e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KDIFEGBE_00032 1.8e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KDIFEGBE_00033 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KDIFEGBE_00034 2e-57 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KDIFEGBE_00035 4e-136 S HAD hydrolase, family IA, variant
KDIFEGBE_00036 7.8e-157 rrmA 2.1.1.187 Q methyltransferase
KDIFEGBE_00040 6.6e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KDIFEGBE_00041 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KDIFEGBE_00042 5e-114 S CAAX protease self-immunity
KDIFEGBE_00043 6.7e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KDIFEGBE_00045 7.9e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KDIFEGBE_00046 2.7e-08 XK27_10305 S Domain of unknown function (DUF4651)
KDIFEGBE_00047 4.8e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KDIFEGBE_00048 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KDIFEGBE_00049 9.6e-102 S CAAX amino terminal protease family protein
KDIFEGBE_00051 2.1e-104 V CAAX protease self-immunity
KDIFEGBE_00052 1.3e-25 lanR K sequence-specific DNA binding
KDIFEGBE_00053 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KDIFEGBE_00054 5e-176 ytxK 2.1.1.72 L DNA methylase
KDIFEGBE_00055 2e-12 comGF U Putative Competence protein ComGF
KDIFEGBE_00056 5.4e-69 comGF U Competence protein ComGF
KDIFEGBE_00057 5.3e-15 NU Type II secretory pathway pseudopilin
KDIFEGBE_00058 1.4e-69 cglD NU Competence protein
KDIFEGBE_00059 2.2e-43 comGC U Required for transformation and DNA binding
KDIFEGBE_00060 6.3e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KDIFEGBE_00061 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KDIFEGBE_00062 1e-68 S cog cog4699
KDIFEGBE_00063 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
KDIFEGBE_00064 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KDIFEGBE_00065 4e-229 cinA 3.5.1.42 S Belongs to the CinA family
KDIFEGBE_00066 7.1e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
KDIFEGBE_00067 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KDIFEGBE_00069 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KDIFEGBE_00071 8.4e-70 K LytTr DNA-binding domain
KDIFEGBE_00072 1.2e-79 S Protein of unknown function (DUF3021)
KDIFEGBE_00073 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KDIFEGBE_00074 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KDIFEGBE_00075 6.9e-69 argR K Regulates arginine biosynthesis genes
KDIFEGBE_00076 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KDIFEGBE_00077 5.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KDIFEGBE_00082 6.1e-16
KDIFEGBE_00083 5.1e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KDIFEGBE_00084 5.9e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KDIFEGBE_00085 3.2e-239 purD 6.3.4.13 F Belongs to the GARS family
KDIFEGBE_00086 3.3e-155 S CHAP domain
KDIFEGBE_00087 2.6e-291 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KDIFEGBE_00088 5.2e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KDIFEGBE_00089 7.2e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KDIFEGBE_00090 6.4e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KDIFEGBE_00091 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KDIFEGBE_00092 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KDIFEGBE_00093 2.4e-29 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KDIFEGBE_00094 9.2e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KDIFEGBE_00095 1e-139 recO L Involved in DNA repair and RecF pathway recombination
KDIFEGBE_00096 9.4e-217 araT 2.6.1.1 E Aminotransferase
KDIFEGBE_00097 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KDIFEGBE_00098 4.5e-83 usp 3.5.1.28 CBM50 S CHAP domain
KDIFEGBE_00099 2.3e-82 mreD M rod shape-determining protein MreD
KDIFEGBE_00100 1.7e-87 mreC M Involved in formation and maintenance of cell shape
KDIFEGBE_00106 2.6e-10
KDIFEGBE_00114 1.1e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KDIFEGBE_00115 2.7e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
KDIFEGBE_00116 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KDIFEGBE_00117 3.6e-228 vicK 2.7.13.3 T Histidine kinase
KDIFEGBE_00118 1.7e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KDIFEGBE_00119 6.7e-57 S Protein of unknown function (DUF454)
KDIFEGBE_00120 2.3e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
KDIFEGBE_00121 7.8e-146 yidA S hydrolases of the HAD superfamily
KDIFEGBE_00122 5.4e-145 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
KDIFEGBE_00123 5.3e-68 ywiB S Domain of unknown function (DUF1934)
KDIFEGBE_00124 0.0 pacL 3.6.3.8 P cation transport ATPase
KDIFEGBE_00125 3.1e-133 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KDIFEGBE_00126 1.5e-155 yjjH S Calcineurin-like phosphoesterase
KDIFEGBE_00127 1.9e-203 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KDIFEGBE_00128 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KDIFEGBE_00129 3.2e-124 ftsE D cell division ATP-binding protein FtsE
KDIFEGBE_00130 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KDIFEGBE_00131 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
KDIFEGBE_00132 7.3e-177 yubA S permease
KDIFEGBE_00133 1.2e-222 G COG0457 FOG TPR repeat
KDIFEGBE_00134 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KDIFEGBE_00135 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KDIFEGBE_00136 3.1e-231 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KDIFEGBE_00137 8.6e-87 ebsA S Family of unknown function (DUF5322)
KDIFEGBE_00138 2.5e-17 M LysM domain
KDIFEGBE_00139 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KDIFEGBE_00140 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KDIFEGBE_00141 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KDIFEGBE_00142 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KDIFEGBE_00143 1.9e-83 XK27_03610 K Gnat family
KDIFEGBE_00144 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KDIFEGBE_00145 2.1e-271 pepV 3.5.1.18 E Dipeptidase
KDIFEGBE_00146 3.6e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
KDIFEGBE_00147 1.5e-12
KDIFEGBE_00149 2.4e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KDIFEGBE_00150 1.9e-138 glnQ 3.6.3.21 E abc transporter atp-binding protein
KDIFEGBE_00151 6.5e-111 tcyB_2 P ABC transporter (permease)
KDIFEGBE_00152 1.9e-116 gltJ P ABC transporter (Permease
KDIFEGBE_00153 8.7e-43 bipA Q Transposase
KDIFEGBE_00154 1.3e-38 M COG3209 Rhs family protein
KDIFEGBE_00161 3.9e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
KDIFEGBE_00162 1.5e-104 S Domain of unknown function (DUF1803)
KDIFEGBE_00163 7.8e-102 ygaC J Belongs to the UPF0374 family
KDIFEGBE_00164 5.4e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
KDIFEGBE_00165 4.5e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KDIFEGBE_00166 8.8e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
KDIFEGBE_00167 3.1e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
KDIFEGBE_00168 8.1e-114 S HAD hydrolase, family IA, variant 3
KDIFEGBE_00169 3.1e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
KDIFEGBE_00170 5.2e-72 marR K Transcriptional regulator, MarR family
KDIFEGBE_00171 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KDIFEGBE_00172 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KDIFEGBE_00173 9.9e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
KDIFEGBE_00174 3.3e-161 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KDIFEGBE_00175 1.1e-125 IQ reductase
KDIFEGBE_00176 1.3e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KDIFEGBE_00177 1.6e-53 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KDIFEGBE_00178 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KDIFEGBE_00179 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KDIFEGBE_00180 3.9e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KDIFEGBE_00181 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KDIFEGBE_00182 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KDIFEGBE_00183 1.9e-207 rny D Endoribonuclease that initiates mRNA decay
KDIFEGBE_00184 1.4e-112 fruR K transcriptional
KDIFEGBE_00185 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KDIFEGBE_00186 0.0 fruA 2.7.1.202 G phosphotransferase system
KDIFEGBE_00187 4.6e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KDIFEGBE_00188 1.9e-228 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KDIFEGBE_00190 3.5e-208 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KDIFEGBE_00191 3.7e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KDIFEGBE_00192 9.7e-291 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KDIFEGBE_00193 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KDIFEGBE_00194 2.4e-90 2.3.1.128 K acetyltransferase
KDIFEGBE_00195 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KDIFEGBE_00196 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KDIFEGBE_00197 9.4e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KDIFEGBE_00198 5e-63 WQ51_03320 S cog cog4835
KDIFEGBE_00199 9.6e-147 XK27_08360 S EDD domain protein, DegV family
KDIFEGBE_00200 3.9e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KDIFEGBE_00201 9.6e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KDIFEGBE_00202 0.0 yfmR S abc transporter atp-binding protein
KDIFEGBE_00203 1.3e-26 U response to pH
KDIFEGBE_00204 3.1e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
KDIFEGBE_00205 5.5e-211 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KDIFEGBE_00206 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KDIFEGBE_00207 1.7e-280 S Psort location CytoplasmicMembrane, score
KDIFEGBE_00208 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KDIFEGBE_00209 4.1e-72 K DNA-binding transcription factor activity
KDIFEGBE_00210 0.0 lmrA1 V abc transporter atp-binding protein
KDIFEGBE_00211 0.0 lmrA2 V abc transporter atp-binding protein
KDIFEGBE_00212 1.9e-112 K Acetyltransferase (GNAT) family
KDIFEGBE_00213 3.7e-111 2.7.6.5 S Region found in RelA / SpoT proteins
KDIFEGBE_00214 2.9e-117 T response regulator
KDIFEGBE_00215 1.3e-216 sptS 2.7.13.3 T Histidine kinase
KDIFEGBE_00216 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KDIFEGBE_00217 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KDIFEGBE_00218 6.5e-159 cvfB S Protein conserved in bacteria
KDIFEGBE_00219 3.7e-34 yozE S Belongs to the UPF0346 family
KDIFEGBE_00220 7.7e-124 sip M LysM domain protein
KDIFEGBE_00221 3.1e-187 phoH T phosphate starvation-inducible protein PhoH
KDIFEGBE_00225 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KDIFEGBE_00226 3.8e-159 S reductase
KDIFEGBE_00227 4.7e-168 K transcriptional regulator (lysR family)
KDIFEGBE_00228 4.2e-106 S CAAX amino terminal protease family protein
KDIFEGBE_00229 1.2e-274 S Glucan-binding protein C
KDIFEGBE_00230 4.7e-174 coiA 3.6.4.12 S Competence protein
KDIFEGBE_00231 0.0 pepF E oligoendopeptidase F
KDIFEGBE_00232 3.5e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
KDIFEGBE_00233 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
KDIFEGBE_00234 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
KDIFEGBE_00235 3e-84 yxjI S LURP-one-related
KDIFEGBE_00236 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KDIFEGBE_00237 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KDIFEGBE_00238 3e-136 agrA KT response regulator
KDIFEGBE_00239 1.5e-06
KDIFEGBE_00240 3.5e-83 L Transposase
KDIFEGBE_00241 1.8e-59 L Transposase and inactivated derivatives
KDIFEGBE_00243 1.3e-201 6.3.5.4 E Asparagine synthase
KDIFEGBE_00244 6.2e-33 S Coenzyme PQQ synthesis protein D (PqqD)
KDIFEGBE_00245 0.0 V ABC transporter transmembrane region
KDIFEGBE_00246 7.4e-124 V AAA domain, putative AbiEii toxin, Type IV TA system
KDIFEGBE_00247 1.1e-123 S ABC-2 family transporter protein
KDIFEGBE_00248 6.1e-78
KDIFEGBE_00249 3.3e-105 T Transcriptional regulatory protein, C terminal
KDIFEGBE_00250 2.9e-159 2.7.13.3 T Histidine kinase
KDIFEGBE_00251 2.2e-39 L Integrase core domain
KDIFEGBE_00252 2.5e-50 L transposase and inactivated derivatives, IS30 family
KDIFEGBE_00253 1.8e-133 agrA KT phosphorelay signal transduction system
KDIFEGBE_00254 3.5e-228 2.7.13.3 T GHKL domain
KDIFEGBE_00255 3.9e-15
KDIFEGBE_00257 4.2e-101 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
KDIFEGBE_00258 7.3e-141 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KDIFEGBE_00259 1.8e-223 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KDIFEGBE_00260 3.1e-184 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KDIFEGBE_00261 7.8e-219 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KDIFEGBE_00262 8.7e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KDIFEGBE_00263 8.2e-202 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KDIFEGBE_00264 1.4e-132 yxkH G deacetylase
KDIFEGBE_00265 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KDIFEGBE_00266 2e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KDIFEGBE_00267 3.1e-148 rarD S Transporter
KDIFEGBE_00268 8.3e-15 T peptidase
KDIFEGBE_00269 3e-14 coiA 3.6.4.12 S Competence protein
KDIFEGBE_00272 2.6e-103 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KDIFEGBE_00273 6.5e-99 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
KDIFEGBE_00274 5.6e-98 F Shikimate kinase
KDIFEGBE_00275 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KDIFEGBE_00276 9.6e-245 V site-specific DNA-methyltransferase (adenine-specific) activity
KDIFEGBE_00277 0.0 T Histidine kinase
KDIFEGBE_00279 3.1e-83 L HNH nucleases
KDIFEGBE_00280 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KDIFEGBE_00281 3.4e-121 atpB C it plays a direct role in the translocation of protons across the membrane
KDIFEGBE_00282 3.6e-61 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KDIFEGBE_00283 3.9e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KDIFEGBE_00284 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KDIFEGBE_00285 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KDIFEGBE_00286 6.7e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KDIFEGBE_00287 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KDIFEGBE_00288 1.2e-217 ftsW D Belongs to the SEDS family
KDIFEGBE_00289 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KDIFEGBE_00290 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KDIFEGBE_00291 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KDIFEGBE_00293 2.3e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KDIFEGBE_00294 3.9e-159 holB 2.7.7.7 L dna polymerase iii
KDIFEGBE_00295 1.3e-132 yaaT S stage 0 sporulation protein
KDIFEGBE_00296 1.2e-54 yabA L Involved in initiation control of chromosome replication
KDIFEGBE_00297 2.8e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KDIFEGBE_00298 2.8e-227 amt P Ammonium Transporter
KDIFEGBE_00299 1.9e-53 glnB K Belongs to the P(II) protein family
KDIFEGBE_00300 1.2e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
KDIFEGBE_00301 1.9e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
KDIFEGBE_00302 2.2e-80 S Bacterial inner membrane protein
KDIFEGBE_00303 9.8e-112 3.4.17.14, 3.5.1.28 NU amidase activity
KDIFEGBE_00304 3.5e-294 nptA P COG1283 Na phosphate symporter
KDIFEGBE_00305 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KDIFEGBE_00306 4.6e-222 S membrane
KDIFEGBE_00307 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KDIFEGBE_00308 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KDIFEGBE_00309 1.7e-38 ynzC S UPF0291 protein
KDIFEGBE_00310 7.9e-255 cycA E permease
KDIFEGBE_00311 6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
KDIFEGBE_00312 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KDIFEGBE_00313 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KDIFEGBE_00317 6e-66 K Helix-turn-helix
KDIFEGBE_00318 5.9e-16
KDIFEGBE_00320 4.7e-168 fhuR K transcriptional regulator (lysR family)
KDIFEGBE_00321 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KDIFEGBE_00322 2.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KDIFEGBE_00323 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KDIFEGBE_00324 1.2e-222 pyrP F uracil Permease
KDIFEGBE_00325 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KDIFEGBE_00326 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
KDIFEGBE_00327 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
KDIFEGBE_00328 2.6e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
KDIFEGBE_00329 1.4e-178 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KDIFEGBE_00330 6.8e-122 macB V ABC transporter, ATP-binding protein
KDIFEGBE_00331 7.9e-211 V permease protein
KDIFEGBE_00332 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KDIFEGBE_00333 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KDIFEGBE_00337 2e-15 D ftsk spoiiie
KDIFEGBE_00338 3.5e-142
KDIFEGBE_00339 2.6e-14 S Domain of unknown function (DUF3173)
KDIFEGBE_00340 2.9e-189 L DNA integration
KDIFEGBE_00341 0.0 mdlB V abc transporter atp-binding protein
KDIFEGBE_00342 0.0 lmrA V abc transporter atp-binding protein
KDIFEGBE_00343 5.6e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KDIFEGBE_00344 2.2e-120 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KDIFEGBE_00345 1.2e-196 yceA S Belongs to the UPF0176 family
KDIFEGBE_00346 1.6e-28 XK27_00085 K Transcriptional
KDIFEGBE_00347 2.7e-24
KDIFEGBE_00348 9.1e-136 deoD_1 2.4.2.3 F Phosphorylase superfamily
KDIFEGBE_00349 3.9e-114 S VIT family
KDIFEGBE_00350 4.7e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KDIFEGBE_00351 7.7e-216 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KDIFEGBE_00352 1.2e-197 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KDIFEGBE_00354 1.9e-128 E alpha/beta hydrolase fold
KDIFEGBE_00355 3.3e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KDIFEGBE_00356 5.1e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KDIFEGBE_00357 1e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KDIFEGBE_00358 4.9e-166 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KDIFEGBE_00359 3.6e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KDIFEGBE_00360 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KDIFEGBE_00361 3.3e-245 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KDIFEGBE_00362 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
KDIFEGBE_00363 1.1e-24
KDIFEGBE_00364 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KDIFEGBE_00365 0.0 U protein secretion
KDIFEGBE_00366 1.5e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
KDIFEGBE_00367 1.2e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KDIFEGBE_00368 8.8e-10
KDIFEGBE_00369 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KDIFEGBE_00370 1.3e-157 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KDIFEGBE_00371 2.1e-199 S Protein of unknown function (DUF3114)
KDIFEGBE_00372 4.1e-29 pspC KT PspC domain protein
KDIFEGBE_00373 5.2e-119 yqfA K protein, Hemolysin III
KDIFEGBE_00374 3e-78 K hmm pf08876
KDIFEGBE_00375 7.7e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KDIFEGBE_00376 4e-212 mvaS 2.3.3.10 I synthase
KDIFEGBE_00377 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KDIFEGBE_00378 5.8e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KDIFEGBE_00379 9.7e-22
KDIFEGBE_00380 4.4e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KDIFEGBE_00381 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
KDIFEGBE_00382 5.8e-250 mmuP E amino acid
KDIFEGBE_00383 2.3e-173 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KDIFEGBE_00384 2.2e-30 S Domain of unknown function (DUF1912)
KDIFEGBE_00385 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
KDIFEGBE_00386 7.4e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KDIFEGBE_00387 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KDIFEGBE_00388 7.1e-147 aadK G adenylyltransferase
KDIFEGBE_00389 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KDIFEGBE_00390 3.1e-200 ilvE 2.6.1.42 E Aminotransferase
KDIFEGBE_00391 4.8e-16 S Protein of unknown function (DUF2969)
KDIFEGBE_00394 7.1e-204 rpsA 1.17.7.4 J ribosomal protein S1
KDIFEGBE_00397 1e-105 S Domain of Unknown Function with PDB structure (DUF3862)
KDIFEGBE_00398 4.9e-82 M Pfam SNARE associated Golgi protein
KDIFEGBE_00399 2.5e-228 murN 2.3.2.16 V FemAB family
KDIFEGBE_00400 2.6e-172 S oxidoreductase
KDIFEGBE_00401 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
KDIFEGBE_00402 5.1e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KDIFEGBE_00403 0.0 clpE O Belongs to the ClpA ClpB family
KDIFEGBE_00404 6.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KDIFEGBE_00405 1e-34 ykuJ S protein conserved in bacteria
KDIFEGBE_00406 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
KDIFEGBE_00407 6.4e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
KDIFEGBE_00408 2.7e-77 feoA P FeoA domain protein
KDIFEGBE_00409 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KDIFEGBE_00410 6.6e-08
KDIFEGBE_00411 3.6e-148 I Alpha/beta hydrolase family
KDIFEGBE_00412 1.4e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KDIFEGBE_00413 8.3e-143 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KDIFEGBE_00414 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
KDIFEGBE_00415 1.7e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KDIFEGBE_00416 7.5e-152 licT K antiterminator
KDIFEGBE_00417 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KDIFEGBE_00418 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KDIFEGBE_00419 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KDIFEGBE_00420 2.5e-152 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KDIFEGBE_00421 6e-103 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KDIFEGBE_00422 2.1e-219 mdtG EGP Major facilitator Superfamily
KDIFEGBE_00423 2e-33 secG U Preprotein translocase subunit SecG
KDIFEGBE_00424 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KDIFEGBE_00425 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KDIFEGBE_00426 3.7e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KDIFEGBE_00427 3.8e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
KDIFEGBE_00428 1.1e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KDIFEGBE_00429 3.2e-181 ccpA K Catabolite control protein A
KDIFEGBE_00430 6.5e-201 yyaQ S YjbR
KDIFEGBE_00431 2.4e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KDIFEGBE_00432 1.1e-77 yueI S Protein of unknown function (DUF1694)
KDIFEGBE_00433 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KDIFEGBE_00434 1.2e-25 WQ51_00785
KDIFEGBE_00435 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KDIFEGBE_00436 4.5e-219 ywbD 2.1.1.191 J Methyltransferase
KDIFEGBE_00437 2e-115 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KDIFEGBE_00438 3.7e-154 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KDIFEGBE_00439 7.2e-200 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KDIFEGBE_00440 1.7e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KDIFEGBE_00441 3.5e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KDIFEGBE_00442 4.2e-53 yheA S Belongs to the UPF0342 family
KDIFEGBE_00443 2.9e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KDIFEGBE_00444 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KDIFEGBE_00445 1e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KDIFEGBE_00446 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
KDIFEGBE_00447 2e-245 msrR K Transcriptional regulator
KDIFEGBE_00448 9.3e-151 ydiA P C4-dicarboxylate transporter malic acid transport
KDIFEGBE_00449 8.5e-201 I acyl-CoA dehydrogenase
KDIFEGBE_00450 2e-97 mip S hydroperoxide reductase activity
KDIFEGBE_00451 1.5e-250 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KDIFEGBE_00452 7.5e-16 K Helix-turn-helix domain
KDIFEGBE_00453 1.7e-12
KDIFEGBE_00454 6.5e-243 L Transposase
KDIFEGBE_00455 1.4e-25
KDIFEGBE_00456 4.1e-276 L resolvase
KDIFEGBE_00457 1.7e-72 S Recombinase
KDIFEGBE_00458 1.8e-254 L resolvase
KDIFEGBE_00459 2e-217 EGP Transmembrane secretion effector
KDIFEGBE_00460 1.8e-254 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
KDIFEGBE_00461 6.1e-75 S DinB superfamily
KDIFEGBE_00462 2.3e-83 ydjA C Nitroreductase family
KDIFEGBE_00463 7.9e-61 yqkA K GrpB protein
KDIFEGBE_00464 3.5e-112 cat 2.3.1.28 V This enzyme is an effector of chloramphenicol resistance in bacteria
KDIFEGBE_00465 5.5e-91 Q Nodulation protein S (NodS)
KDIFEGBE_00466 6.3e-123 U COG COG3505 Type IV secretory pathway, VirD4 components
KDIFEGBE_00467 3.4e-70 L Integrase core domain
KDIFEGBE_00468 1e-17 S alpha beta
KDIFEGBE_00469 4.8e-65 yvbK 3.1.3.25 K Acetyltransferase (GNAT) domain
KDIFEGBE_00470 5.9e-100 J Acetyltransferase (GNAT) domain
KDIFEGBE_00471 2.3e-96
KDIFEGBE_00472 3e-113 K Bacterial regulatory proteins, tetR family
KDIFEGBE_00473 6.5e-115 S ABC-type transport system involved in multi-copper enzyme maturation, permease component
KDIFEGBE_00474 1.1e-130 bcrA V abc transporter atp-binding protein
KDIFEGBE_00475 7e-290 V ABC transporter transmembrane region
KDIFEGBE_00476 6.6e-12
KDIFEGBE_00477 2.3e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KDIFEGBE_00478 1.6e-129 S Domain of unknown function (DUF4336)
KDIFEGBE_00479 5.3e-204 yeaN P transporter
KDIFEGBE_00480 1.7e-151 yitS S EDD domain protein, DegV family
KDIFEGBE_00481 4.9e-94 XK27_08140 K Bacterial regulatory proteins, tetR family
KDIFEGBE_00482 1.4e-110 cutC P Participates in the control of copper homeostasis
KDIFEGBE_00484 3.2e-21 S Domain of unknown function (DUF4767)
KDIFEGBE_00485 1.1e-153 S Domain of unknown function (DUF4300)
KDIFEGBE_00486 6.6e-123 V CAAX protease self-immunity
KDIFEGBE_00487 1.4e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KDIFEGBE_00488 1.4e-133 fecE 3.6.3.34 HP ABC transporter
KDIFEGBE_00489 3.8e-174 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KDIFEGBE_00490 1.6e-120 ybbA S Putative esterase
KDIFEGBE_00491 1.3e-157 yegS 2.7.1.107 I Diacylglycerol kinase
KDIFEGBE_00492 3.6e-172 S Domain of unknown function (DUF389)
KDIFEGBE_00493 7.2e-31 S Membrane
KDIFEGBE_00494 5.5e-98
KDIFEGBE_00495 1.3e-21 S Small integral membrane protein
KDIFEGBE_00496 1.2e-68 S Asp23 family, cell envelope-related function
KDIFEGBE_00497 3.3e-08 K CsbD-like
KDIFEGBE_00498 3.3e-08 K CsbD-like
KDIFEGBE_00499 1.2e-172 pdhD 1.8.1.4 C Dehydrogenase
KDIFEGBE_00500 9e-166 acoA C Acetoin dehydrogenase E1 component subunit alpha
KDIFEGBE_00501 4.6e-175 acoB C dehydrogenase E1 component
KDIFEGBE_00502 6.7e-141 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KDIFEGBE_00503 1.8e-83 Q Methyltransferase domain
KDIFEGBE_00504 2.9e-78 K TetR family transcriptional regulator
KDIFEGBE_00505 5.8e-49
KDIFEGBE_00506 1.7e-126 V CAAX protease self-immunity
KDIFEGBE_00507 1.5e-10
KDIFEGBE_00508 8.4e-19 S Bacterial lipoprotein
KDIFEGBE_00509 4.1e-60 S Protein of unknown function (DUF1722)
KDIFEGBE_00510 2.2e-63 yqeB S Pyrimidine dimer DNA glycosylase
KDIFEGBE_00512 9.4e-51
KDIFEGBE_00513 8.9e-94 S CAAX protease self-immunity
KDIFEGBE_00514 8.4e-119 estA E GDSL-like Lipase/Acylhydrolase
KDIFEGBE_00515 1.2e-101
KDIFEGBE_00516 2.1e-286 sulP P Sulfate permease and related transporters (MFS superfamily)
KDIFEGBE_00517 9.9e-149 ycgQ S TIGR03943 family
KDIFEGBE_00518 1.9e-156 XK27_03015 S permease
KDIFEGBE_00520 0.0 yhgF K Transcriptional accessory protein
KDIFEGBE_00521 3.9e-83 ydcK S Belongs to the SprT family
KDIFEGBE_00522 2.2e-41 pspC KT PspC domain
KDIFEGBE_00523 2.2e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KDIFEGBE_00524 1.2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KDIFEGBE_00525 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KDIFEGBE_00526 3e-67 ytxH S General stress protein
KDIFEGBE_00528 1.7e-176 yegQ O Peptidase U32
KDIFEGBE_00529 1.7e-251 yegQ O Peptidase U32
KDIFEGBE_00530 2.5e-87 bioY S biotin synthase
KDIFEGBE_00532 1.1e-33 XK27_12190 S protein conserved in bacteria
KDIFEGBE_00533 3.3e-234 mntH P H( )-stimulated, divalent metal cation uptake system
KDIFEGBE_00534 6.7e-13
KDIFEGBE_00535 4.1e-210 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KDIFEGBE_00536 8.2e-226 mutH L DNA mismatch repair enzyme MutH
KDIFEGBE_00537 4.5e-202 S SIR2-like domain
KDIFEGBE_00538 3.3e-236 S Domain of unknown function DUF87
KDIFEGBE_00540 2.8e-35
KDIFEGBE_00541 3.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KDIFEGBE_00542 4.3e-138 M LysM domain
KDIFEGBE_00543 8.4e-23
KDIFEGBE_00544 5.2e-175 S hydrolase
KDIFEGBE_00546 7.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
KDIFEGBE_00547 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KDIFEGBE_00548 3.5e-139 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
KDIFEGBE_00549 1.3e-26 P Hemerythrin HHE cation binding domain protein
KDIFEGBE_00550 1.2e-152 5.2.1.8 G hydrolase
KDIFEGBE_00551 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KDIFEGBE_00552 3.1e-212 MA20_36090 S Protein of unknown function (DUF2974)
KDIFEGBE_00553 7.9e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KDIFEGBE_00555 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KDIFEGBE_00556 6.6e-95
KDIFEGBE_00557 1.4e-19
KDIFEGBE_00559 5.2e-133 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
KDIFEGBE_00560 0.0 S KAP family P-loop domain
KDIFEGBE_00561 2.3e-128 S Protein conserved in bacteria
KDIFEGBE_00562 2.1e-304 hsdM 2.1.1.72 V type I restriction-modification system
KDIFEGBE_00563 1e-133 S double-stranded DNA endodeoxyribonuclease activity
KDIFEGBE_00564 0.0 2.4.1.21 GT5 M Right handed beta helix region
KDIFEGBE_00565 2.9e-174 spd F DNA RNA non-specific endonuclease
KDIFEGBE_00566 7.7e-92 lemA S LemA family
KDIFEGBE_00567 4e-135 htpX O Belongs to the peptidase M48B family
KDIFEGBE_00568 5e-119 sirR K iron dependent repressor
KDIFEGBE_00569 1.2e-171 sitA P Belongs to the bacterial solute-binding protein 9 family
KDIFEGBE_00570 4.6e-133 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
KDIFEGBE_00571 2.8e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
KDIFEGBE_00572 1.6e-74 S Psort location CytoplasmicMembrane, score
KDIFEGBE_00573 5.6e-65 S Domain of unknown function (DUF4430)
KDIFEGBE_00574 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KDIFEGBE_00575 1.6e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
KDIFEGBE_00576 2.7e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
KDIFEGBE_00577 6e-170 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
KDIFEGBE_00578 8.1e-101 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
KDIFEGBE_00579 9e-79 dps P Belongs to the Dps family
KDIFEGBE_00580 3.4e-79 perR P Belongs to the Fur family
KDIFEGBE_00581 2.4e-27 yqgQ S protein conserved in bacteria
KDIFEGBE_00582 7.8e-177 glk 2.7.1.2 G Glucokinase
KDIFEGBE_00583 0.0 typA T GTP-binding protein TypA
KDIFEGBE_00585 5.1e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KDIFEGBE_00586 2.8e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KDIFEGBE_00587 6.9e-132 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KDIFEGBE_00588 3.5e-223 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KDIFEGBE_00589 4.3e-234 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KDIFEGBE_00590 6.2e-120 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KDIFEGBE_00591 1.1e-93 sepF D cell septum assembly
KDIFEGBE_00592 1.7e-30 yggT D integral membrane protein
KDIFEGBE_00593 9.5e-136 ylmH S conserved protein, contains S4-like domain
KDIFEGBE_00594 5.5e-137 divIVA D Cell division initiation protein
KDIFEGBE_00595 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KDIFEGBE_00596 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KDIFEGBE_00597 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KDIFEGBE_00598 6.5e-34 nrdH O Glutaredoxin
KDIFEGBE_00599 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KDIFEGBE_00600 2.8e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
KDIFEGBE_00601 7.4e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
KDIFEGBE_00602 3e-38 ptsH G phosphocarrier protein Hpr
KDIFEGBE_00603 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KDIFEGBE_00604 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KDIFEGBE_00605 6.1e-162 XK27_05670 S Putative esterase
KDIFEGBE_00606 2.7e-153 XK27_05675 S Esterase
KDIFEGBE_00607 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
KDIFEGBE_00608 6e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
KDIFEGBE_00609 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
KDIFEGBE_00610 0.0 uup S abc transporter atp-binding protein
KDIFEGBE_00611 1.6e-39 MA20_06245 S yiaA/B two helix domain
KDIFEGBE_00612 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
KDIFEGBE_00613 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KDIFEGBE_00614 8.7e-150 cobQ S glutamine amidotransferase
KDIFEGBE_00615 1.7e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
KDIFEGBE_00616 1.5e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KDIFEGBE_00617 3.8e-163 ybbR S Protein conserved in bacteria
KDIFEGBE_00618 5.7e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KDIFEGBE_00619 1.3e-64 gtrA S GtrA-like protein
KDIFEGBE_00620 4e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
KDIFEGBE_00621 7.1e-144 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KDIFEGBE_00622 5.7e-144 zupT P Mediates zinc uptake. May also transport other divalent cations
KDIFEGBE_00623 8.7e-201 yurR 1.4.5.1 E oxidoreductase
KDIFEGBE_00624 4.3e-258 S phospholipase Carboxylesterase
KDIFEGBE_00625 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KDIFEGBE_00626 6.4e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KDIFEGBE_00627 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KDIFEGBE_00629 2.9e-30 KT response to antibiotic
KDIFEGBE_00630 1.1e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
KDIFEGBE_00631 9.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
KDIFEGBE_00632 2.3e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KDIFEGBE_00633 3.3e-115 ylfI S tigr01906
KDIFEGBE_00634 2.1e-137 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KDIFEGBE_00635 7.5e-145 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KDIFEGBE_00636 1.1e-60 XK27_08085
KDIFEGBE_00637 1.9e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KDIFEGBE_00638 2.9e-179 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KDIFEGBE_00639 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KDIFEGBE_00640 1.4e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KDIFEGBE_00641 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KDIFEGBE_00642 2.3e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KDIFEGBE_00643 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KDIFEGBE_00644 8.1e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KDIFEGBE_00645 2e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KDIFEGBE_00646 9.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
KDIFEGBE_00648 8.7e-43 bipA Q Transposase
KDIFEGBE_00649 1.8e-61 L thioesterase
KDIFEGBE_00650 1.2e-52 bta 1.8.1.8 CO cell redox homeostasis
KDIFEGBE_00652 6e-143 S Macro domain protein
KDIFEGBE_00653 2.4e-50 trxA O Belongs to the thioredoxin family
KDIFEGBE_00654 2.7e-73 yccU S CoA-binding protein
KDIFEGBE_00655 6.1e-143 tatD L Hydrolase, tatd
KDIFEGBE_00656 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KDIFEGBE_00657 5.8e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KDIFEGBE_00659 1.2e-160 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KDIFEGBE_00660 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KDIFEGBE_00661 2.3e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
KDIFEGBE_00662 2.5e-170 rmuC S RmuC domain protein
KDIFEGBE_00663 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
KDIFEGBE_00664 4e-142 purR 2.4.2.7 F operon repressor
KDIFEGBE_00665 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KDIFEGBE_00666 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KDIFEGBE_00667 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KDIFEGBE_00668 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
KDIFEGBE_00669 5.6e-124
KDIFEGBE_00670 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KDIFEGBE_00671 8.7e-87 S Fusaric acid resistance protein-like
KDIFEGBE_00672 2.5e-62 glnR K Transcriptional regulator
KDIFEGBE_00673 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
KDIFEGBE_00674 8e-114 pscB M CHAP domain protein
KDIFEGBE_00675 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KDIFEGBE_00676 1.5e-33 ykzG S Belongs to the UPF0356 family
KDIFEGBE_00677 1.3e-114 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
KDIFEGBE_00678 9e-72 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KDIFEGBE_00679 3.1e-184 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KDIFEGBE_00680 2.2e-112 azlC E AzlC protein
KDIFEGBE_00681 7.5e-47 azlD S branched-chain amino acid
KDIFEGBE_00682 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KDIFEGBE_00683 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KDIFEGBE_00684 4.2e-153 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KDIFEGBE_00685 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KDIFEGBE_00686 6.1e-94 cvpA S toxin biosynthetic process
KDIFEGBE_00687 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KDIFEGBE_00688 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KDIFEGBE_00690 1.3e-37
KDIFEGBE_00691 7.6e-10
KDIFEGBE_00693 2.7e-224 mutY L A G-specific adenine glycosylase
KDIFEGBE_00694 2.7e-41 XK27_05745
KDIFEGBE_00695 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KDIFEGBE_00696 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KDIFEGBE_00697 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KDIFEGBE_00699 2.9e-122 XK27_01040 S Protein of unknown function (DUF1129)
KDIFEGBE_00700 4.2e-167 corA P COG0598 Mg2 and Co2 transporters
KDIFEGBE_00701 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KDIFEGBE_00705 1.2e-32 blpT
KDIFEGBE_00706 1.1e-144 V 'abc transporter, ATP-binding protein
KDIFEGBE_00708 4.1e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
KDIFEGBE_00709 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
KDIFEGBE_00710 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KDIFEGBE_00711 1.7e-61 yqhY S protein conserved in bacteria
KDIFEGBE_00712 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KDIFEGBE_00713 1.2e-177 scrR K Transcriptional regulator
KDIFEGBE_00714 1.2e-285 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
KDIFEGBE_00715 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KDIFEGBE_00716 7.7e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
KDIFEGBE_00717 8.2e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
KDIFEGBE_00719 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KDIFEGBE_00720 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KDIFEGBE_00721 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KDIFEGBE_00722 4.7e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KDIFEGBE_00723 2.1e-202 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KDIFEGBE_00724 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KDIFEGBE_00728 2.9e-31 yozG K Transcriptional regulator
KDIFEGBE_00730 2.6e-169 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KDIFEGBE_00731 2.4e-259 XK27_03190 S hydrolases of the HAD superfamily
KDIFEGBE_00732 2e-102 yebC M Membrane
KDIFEGBE_00733 3.4e-308 KT response to antibiotic
KDIFEGBE_00734 1.3e-73 XK27_02470 K LytTr DNA-binding domain
KDIFEGBE_00735 5.3e-119 liaI S membrane
KDIFEGBE_00736 8.7e-78 mccF V LD-carboxypeptidase
KDIFEGBE_00737 5.3e-43 S Sugar efflux transporter for intercellular exchange
KDIFEGBE_00738 2.6e-194 mccF V LD-carboxypeptidase
KDIFEGBE_00739 1.7e-298 O MreB/Mbl protein
KDIFEGBE_00741 5.8e-146 V Psort location CytoplasmicMembrane, score
KDIFEGBE_00744 6.8e-14
KDIFEGBE_00745 6.1e-233 dcuS 2.7.13.3 T protein histidine kinase activity
KDIFEGBE_00746 4e-243 2.7.13.3 T protein histidine kinase activity
KDIFEGBE_00747 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KDIFEGBE_00748 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KDIFEGBE_00749 4e-125 S Protein of unknown function (DUF554)
KDIFEGBE_00750 4e-133 ecsA_2 V abc transporter atp-binding protein
KDIFEGBE_00751 3e-266 XK27_00765
KDIFEGBE_00752 7.5e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KDIFEGBE_00753 3.2e-223 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KDIFEGBE_00754 3.4e-54 yhaI S Protein of unknown function (DUF805)
KDIFEGBE_00755 3.8e-61 yhaI J Protein of unknown function (DUF805)
KDIFEGBE_00756 3.7e-48 yhaI J Protein of unknown function (DUF805)
KDIFEGBE_00758 7.2e-96
KDIFEGBE_00759 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KDIFEGBE_00760 2.4e-45 ftsL D cell division protein FtsL
KDIFEGBE_00761 0.0 ftsI 3.4.16.4 M penicillin-binding protein
KDIFEGBE_00762 3.7e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KDIFEGBE_00763 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KDIFEGBE_00764 5.2e-156 V ATPases associated with a variety of cellular activities
KDIFEGBE_00765 3.9e-123
KDIFEGBE_00766 2.3e-128 KT COG3279 Response regulator of the LytR AlgR family
KDIFEGBE_00767 4.6e-214 T GHKL domain
KDIFEGBE_00769 1.1e-256 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KDIFEGBE_00770 1.8e-61 yutD J protein conserved in bacteria
KDIFEGBE_00771 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KDIFEGBE_00772 9.7e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
KDIFEGBE_00775 0.0 mdlA V abc transporter atp-binding protein
KDIFEGBE_00776 0.0 mdlB V abc transporter atp-binding protein
KDIFEGBE_00777 6.8e-10 S Bacteriocin class II with double-glycine leader peptide
KDIFEGBE_00783 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KDIFEGBE_00784 3.6e-157 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KDIFEGBE_00785 2e-91 V CAAX protease self-immunity
KDIFEGBE_00786 4.6e-140 cppA E CppA N-terminal
KDIFEGBE_00787 1.1e-167 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
KDIFEGBE_00790 1.1e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KDIFEGBE_00791 5.4e-144 cah 4.2.1.1 P carbonic anhydrase
KDIFEGBE_00792 0.0 pflB 2.3.1.54 C formate acetyltransferase'
KDIFEGBE_00793 1.6e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KDIFEGBE_00794 4.7e-35
KDIFEGBE_00795 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KDIFEGBE_00796 1.9e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KDIFEGBE_00797 8e-163 yxeN P ABC transporter (Permease
KDIFEGBE_00798 1.4e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
KDIFEGBE_00799 5e-10 S Protein of unknown function (DUF4059)
KDIFEGBE_00800 1.4e-170 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KDIFEGBE_00801 4.2e-104 rsmD 2.1.1.171 L Methyltransferase
KDIFEGBE_00802 6.6e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KDIFEGBE_00803 4.2e-187 ylbL T Belongs to the peptidase S16 family
KDIFEGBE_00804 9.3e-183 yhcC S radical SAM protein
KDIFEGBE_00805 2.2e-96 ytqB J (SAM)-dependent
KDIFEGBE_00807 0.0 yjcE P NhaP-type Na H and K H antiporters
KDIFEGBE_00808 7.9e-25
KDIFEGBE_00810 6.6e-142 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KDIFEGBE_00811 1.5e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
KDIFEGBE_00812 3.3e-10 MU outer membrane autotransporter barrel domain protein
KDIFEGBE_00813 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KDIFEGBE_00815 1.2e-74 XK27_03180 T universal stress protein
KDIFEGBE_00816 1.7e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
KDIFEGBE_00817 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KDIFEGBE_00818 2e-100 pncA Q isochorismatase
KDIFEGBE_00819 2.6e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KDIFEGBE_00820 6.7e-218 M lipopolysaccharide 3-alpha-galactosyltransferase activity
KDIFEGBE_00821 8.2e-157 H COG0463 Glycosyltransferases involved in cell wall biogenesis
KDIFEGBE_00822 5.4e-189 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KDIFEGBE_00823 1.2e-234 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KDIFEGBE_00824 2.6e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KDIFEGBE_00825 2.2e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KDIFEGBE_00826 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KDIFEGBE_00828 4.1e-283 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KDIFEGBE_00829 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
KDIFEGBE_00830 2.9e-279 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
KDIFEGBE_00831 1.7e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
KDIFEGBE_00832 3.2e-57
KDIFEGBE_00833 5.3e-216 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KDIFEGBE_00834 4.6e-64
KDIFEGBE_00835 2.3e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KDIFEGBE_00836 1.4e-98 yqeG S hydrolase of the HAD superfamily
KDIFEGBE_00837 7.1e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KDIFEGBE_00838 2.9e-48 yhbY J RNA-binding protein
KDIFEGBE_00839 4.5e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KDIFEGBE_00840 4.1e-104 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KDIFEGBE_00841 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KDIFEGBE_00842 1.9e-138 yqeM Q Methyltransferase domain protein
KDIFEGBE_00843 1.6e-194 ylbM S Belongs to the UPF0348 family
KDIFEGBE_00844 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
KDIFEGBE_00847 4.1e-07
KDIFEGBE_00848 1e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KDIFEGBE_00849 3.7e-131 ecsA V abc transporter atp-binding protein
KDIFEGBE_00850 1e-174 ecsB U Bacterial ABC transporter protein EcsB
KDIFEGBE_00851 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
KDIFEGBE_00852 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KDIFEGBE_00854 4e-223 ytfP S Flavoprotein
KDIFEGBE_00855 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KDIFEGBE_00856 9.6e-64 XK27_02560 S cog cog2151
KDIFEGBE_00857 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
KDIFEGBE_00858 5.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
KDIFEGBE_00859 8.9e-125 K transcriptional regulator, MerR family
KDIFEGBE_00860 0.0 V ABC transporter (Permease
KDIFEGBE_00861 9.5e-124 V abc transporter atp-binding protein
KDIFEGBE_00863 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KDIFEGBE_00864 4.4e-46
KDIFEGBE_00865 3.1e-47
KDIFEGBE_00866 0.0 ctpE P E1-E2 ATPase
KDIFEGBE_00867 1.2e-59
KDIFEGBE_00868 2.2e-39 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
KDIFEGBE_00869 2e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KDIFEGBE_00870 3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
KDIFEGBE_00871 8.7e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KDIFEGBE_00872 7.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KDIFEGBE_00873 3e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
KDIFEGBE_00874 1.3e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KDIFEGBE_00875 1.5e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KDIFEGBE_00878 7.8e-163 EGP Major facilitator Superfamily
KDIFEGBE_00879 1.8e-72 copY K negative regulation of transcription, DNA-templated
KDIFEGBE_00880 0.0 copA 3.6.3.54 P P-type ATPase
KDIFEGBE_00881 1.4e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
KDIFEGBE_00882 3.5e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KDIFEGBE_00883 6.6e-114 papP P ABC transporter (Permease
KDIFEGBE_00884 4.6e-107 P ABC transporter (Permease
KDIFEGBE_00885 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
KDIFEGBE_00886 3.3e-155 cjaA ET ABC transporter substrate-binding protein
KDIFEGBE_00890 1.6e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KDIFEGBE_00891 5.3e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
KDIFEGBE_00892 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KDIFEGBE_00893 1.7e-99 thiT S Thiamine transporter
KDIFEGBE_00894 3.3e-62 yjqA S Bacterial PH domain
KDIFEGBE_00895 1.6e-152 corA P CorA-like protein
KDIFEGBE_00896 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KDIFEGBE_00897 6.6e-41 yazA L endonuclease containing a URI domain
KDIFEGBE_00898 3.5e-140 yabB 2.1.1.223 L Methyltransferase
KDIFEGBE_00899 8.1e-147 nodB3 G Polysaccharide deacetylase
KDIFEGBE_00900 2.9e-142 plsC 2.3.1.51 I Acyltransferase
KDIFEGBE_00901 1.5e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KDIFEGBE_00902 0.0 comEC S Competence protein ComEC
KDIFEGBE_00903 2.3e-229 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KDIFEGBE_00904 7e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
KDIFEGBE_00905 3e-232 ytoI K transcriptional regulator containing CBS domains
KDIFEGBE_00906 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KDIFEGBE_00907 4.8e-163 rbn E Belongs to the UPF0761 family
KDIFEGBE_00908 1.7e-85 ccl S cog cog4708
KDIFEGBE_00909 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KDIFEGBE_00910 8.4e-182 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KDIFEGBE_00912 2.2e-171 yfjR K regulation of single-species biofilm formation
KDIFEGBE_00914 6.4e-71 S QueT transporter
KDIFEGBE_00915 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
KDIFEGBE_00917 2.7e-199 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KDIFEGBE_00918 3.7e-17 yjdB S Domain of unknown function (DUF4767)
KDIFEGBE_00919 1.5e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
KDIFEGBE_00920 1.1e-165 O protein import
KDIFEGBE_00921 2.6e-124 agrA KT phosphorelay signal transduction system
KDIFEGBE_00922 4.8e-201 2.7.13.3 T protein histidine kinase activity
KDIFEGBE_00924 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KDIFEGBE_00925 1.5e-36 ylqC L Belongs to the UPF0109 family
KDIFEGBE_00926 2e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KDIFEGBE_00927 0.0 ydaO E amino acid
KDIFEGBE_00928 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
KDIFEGBE_00929 4.5e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KDIFEGBE_00930 2.4e-291 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KDIFEGBE_00931 1.7e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KDIFEGBE_00932 3.7e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KDIFEGBE_00933 6.2e-168 murB 1.3.1.98 M cell wall formation
KDIFEGBE_00934 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KDIFEGBE_00935 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
KDIFEGBE_00936 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
KDIFEGBE_00937 1.7e-204 potD P spermidine putrescine ABC transporter
KDIFEGBE_00938 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
KDIFEGBE_00939 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
KDIFEGBE_00940 9.8e-158 GK ROK family
KDIFEGBE_00941 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KDIFEGBE_00942 3e-104 wecD M Acetyltransferase (GNAT) domain
KDIFEGBE_00943 3.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KDIFEGBE_00944 2.1e-67 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
KDIFEGBE_00946 3.5e-56 lrgA S Effector of murein hydrolase LrgA
KDIFEGBE_00947 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KDIFEGBE_00948 4.1e-93 3.1.3.18 S IA, variant 1
KDIFEGBE_00949 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KDIFEGBE_00950 8.4e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KDIFEGBE_00951 2.6e-112 serB 3.1.3.3 E phosphoserine phosphatase
KDIFEGBE_00953 7e-148 EG Permeases of the drug metabolite transporter (DMT) superfamily
KDIFEGBE_00955 6e-61 ycaO O OsmC-like protein
KDIFEGBE_00956 1.1e-62 paaI Q protein possibly involved in aromatic compounds catabolism
KDIFEGBE_00957 2.8e-09 O ADP-ribosylglycohydrolase
KDIFEGBE_00958 5.2e-125 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KDIFEGBE_00960 8.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KDIFEGBE_00961 1.7e-17 XK27_00735
KDIFEGBE_00962 3.9e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
KDIFEGBE_00963 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
KDIFEGBE_00964 5.4e-159 S CAAX amino terminal protease family protein
KDIFEGBE_00966 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KDIFEGBE_00967 1.8e-78 mutT 3.6.1.55 F Nudix family
KDIFEGBE_00968 2.2e-140 ET ABC transporter
KDIFEGBE_00969 7.2e-136 ET Belongs to the bacterial solute-binding protein 3 family
KDIFEGBE_00970 2.5e-211 arcT 2.6.1.1 E Aminotransferase
KDIFEGBE_00971 1.9e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
KDIFEGBE_00972 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KDIFEGBE_00973 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KDIFEGBE_00974 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KDIFEGBE_00975 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KDIFEGBE_00976 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
KDIFEGBE_00977 4e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KDIFEGBE_00978 1.3e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KDIFEGBE_00979 1e-88 S Psort location CytoplasmicMembrane, score
KDIFEGBE_00980 4.3e-220 amrA S membrane protein involved in the export of O-antigen and teichoic acid
KDIFEGBE_00981 1e-176 M Glycosyltransferase group 2 family protein
KDIFEGBE_00982 9.2e-127 arnC M group 2 family protein
KDIFEGBE_00983 3.2e-43 S Uncharacterized conserved protein (DUF2304)
KDIFEGBE_00984 1.7e-150 2.4.1.60 S Glycosyltransferase group 2 family protein
KDIFEGBE_00985 3.9e-93 S Psort location CytoplasmicMembrane, score
KDIFEGBE_00986 8.8e-25 S Psort location CytoplasmicMembrane, score
KDIFEGBE_00987 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
KDIFEGBE_00988 6.6e-221 M Psort location CytoplasmicMembrane, score
KDIFEGBE_00989 5.8e-225 GT4 M transferase activity, transferring glycosyl groups
KDIFEGBE_00990 1.5e-222 rgpA GT4 M Domain of unknown function (DUF1972)
KDIFEGBE_00991 1.6e-171 rgpB GT2 M Glycosyltransferase, group 2 family protein
KDIFEGBE_00992 8.9e-142 rgpC GM Transport permease protein
KDIFEGBE_00993 7.3e-225 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KDIFEGBE_00994 2.6e-305 rgpF M Rhamnan synthesis protein F
KDIFEGBE_00995 7.6e-118 radC E Belongs to the UPF0758 family
KDIFEGBE_00996 5.1e-130 puuD T peptidase C26
KDIFEGBE_00997 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KDIFEGBE_00998 8.2e-60 XK27_04120 S Putative amino acid metabolism
KDIFEGBE_00999 1.4e-206 iscS 2.8.1.7 E Cysteine desulfurase
KDIFEGBE_01000 3.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KDIFEGBE_01001 2.4e-101 yjbK S Adenylate cyclase
KDIFEGBE_01002 1e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
KDIFEGBE_01003 1.3e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KDIFEGBE_01004 3.5e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KDIFEGBE_01005 3e-176 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KDIFEGBE_01006 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KDIFEGBE_01007 2.5e-310 amiA E ABC transporter, substrate-binding protein, family 5
KDIFEGBE_01008 1.1e-275 amiC P ABC transporter (Permease
KDIFEGBE_01009 2.3e-165 amiD P ABC transporter (Permease
KDIFEGBE_01010 2.1e-202 oppD P Belongs to the ABC transporter superfamily
KDIFEGBE_01011 3.6e-171 oppF P Belongs to the ABC transporter superfamily
KDIFEGBE_01012 8.4e-129 V Psort location CytoplasmicMembrane, score
KDIFEGBE_01013 3.5e-118 skfE V abc transporter atp-binding protein
KDIFEGBE_01014 5.6e-62 yvoA_1 K Transcriptional
KDIFEGBE_01015 5.9e-146 supH S overlaps another CDS with the same product name
KDIFEGBE_01016 2.7e-146 XK27_02985 S overlaps another CDS with the same product name
KDIFEGBE_01017 2.4e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KDIFEGBE_01018 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KDIFEGBE_01019 1.4e-45 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
KDIFEGBE_01020 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KDIFEGBE_01021 3.1e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KDIFEGBE_01022 7.8e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KDIFEGBE_01023 1.3e-134 stp 3.1.3.16 T phosphatase
KDIFEGBE_01024 1.4e-291 prkC 2.7.11.1 KLT serine threonine protein kinase
KDIFEGBE_01025 4.1e-104 kcsA P Ion transport protein
KDIFEGBE_01026 1.6e-115 yvqF S Membrane
KDIFEGBE_01027 1.3e-169 vraS 2.7.13.3 T Histidine kinase
KDIFEGBE_01028 1.8e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KDIFEGBE_01031 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KDIFEGBE_01032 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KDIFEGBE_01033 1.9e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KDIFEGBE_01034 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KDIFEGBE_01035 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KDIFEGBE_01036 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KDIFEGBE_01037 1e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KDIFEGBE_01038 5.7e-179 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
KDIFEGBE_01039 9.2e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KDIFEGBE_01040 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KDIFEGBE_01041 1.8e-101 2.3.1.128 K Acetyltransferase GNAT Family
KDIFEGBE_01042 6.1e-285 S Protein of unknown function (DUF3114)
KDIFEGBE_01044 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
KDIFEGBE_01045 5e-299 V abc transporter atp-binding protein
KDIFEGBE_01046 0.0 V abc transporter atp-binding protein
KDIFEGBE_01047 1.7e-186 XK27_10075 S abc transporter atp-binding protein
KDIFEGBE_01048 1.7e-10
KDIFEGBE_01049 0.0 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KDIFEGBE_01050 0.0 M Pilin isopeptide linkage domain protein
KDIFEGBE_01051 3.6e-12
KDIFEGBE_01053 4e-42 bipA S protein secretion
KDIFEGBE_01054 0.0 3.5.1.28 NU amidase activity
KDIFEGBE_01055 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
KDIFEGBE_01056 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KDIFEGBE_01057 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
KDIFEGBE_01058 6.2e-232 ycdB P peroxidase
KDIFEGBE_01059 3.2e-287 ywbL P COG0672 High-affinity Fe2 Pb2 permease
KDIFEGBE_01060 5.4e-119 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KDIFEGBE_01061 3e-24 tatA U protein secretion
KDIFEGBE_01062 7.9e-213 msmX P Belongs to the ABC transporter superfamily
KDIFEGBE_01063 3.7e-151 malG P ABC transporter (Permease
KDIFEGBE_01064 8.2e-249 malF P ABC transporter (Permease
KDIFEGBE_01065 1.5e-228 malX G ABC transporter
KDIFEGBE_01066 2.1e-156 malR K Transcriptional regulator
KDIFEGBE_01067 2.3e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
KDIFEGBE_01068 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KDIFEGBE_01069 1.2e-38
KDIFEGBE_01070 5.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
KDIFEGBE_01071 3.5e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KDIFEGBE_01072 0.0 pepN 3.4.11.2 E aminopeptidase
KDIFEGBE_01073 7.1e-113 phoU P Plays a role in the regulation of phosphate uptake
KDIFEGBE_01074 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KDIFEGBE_01075 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KDIFEGBE_01076 1.5e-155 pstA P phosphate transport system permease
KDIFEGBE_01077 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
KDIFEGBE_01078 1.1e-156 pstS P phosphate
KDIFEGBE_01079 2e-252 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KDIFEGBE_01080 5.9e-143 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KDIFEGBE_01081 1e-44 yktA S Belongs to the UPF0223 family
KDIFEGBE_01082 7.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KDIFEGBE_01083 1.5e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KDIFEGBE_01084 3e-148 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KDIFEGBE_01085 2.5e-245 XK27_04775 S hemerythrin HHE cation binding domain
KDIFEGBE_01086 2.3e-34 M1-755 P Hemerythrin HHE cation binding domain protein
KDIFEGBE_01087 1.4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
KDIFEGBE_01088 3.6e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KDIFEGBE_01089 1.2e-140 S haloacid dehalogenase-like hydrolase
KDIFEGBE_01090 2.8e-238 metY 2.5.1.49 E o-acetylhomoserine
KDIFEGBE_01091 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KDIFEGBE_01092 3.1e-240 agcS E (Alanine) symporter
KDIFEGBE_01093 2.8e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KDIFEGBE_01094 4e-167 bglC K Transcriptional regulator
KDIFEGBE_01095 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KDIFEGBE_01096 1.1e-81 yecS P ABC transporter (Permease
KDIFEGBE_01097 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
KDIFEGBE_01098 4.7e-242 nylA 3.5.1.4 J Belongs to the amidase family
KDIFEGBE_01099 9.8e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KDIFEGBE_01100 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KDIFEGBE_01102 4.5e-177 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KDIFEGBE_01103 2.9e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KDIFEGBE_01104 8.8e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
KDIFEGBE_01105 1.3e-132 S TraX protein
KDIFEGBE_01106 8.6e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KDIFEGBE_01107 3.9e-263 S Psort location CytoplasmicMembrane, score
KDIFEGBE_01108 4e-232 dinF V Mate efflux family protein
KDIFEGBE_01109 4.1e-178 yclQ P ABC-type enterochelin transport system, periplasmic component
KDIFEGBE_01110 0.0 V Type III restriction enzyme, res subunit
KDIFEGBE_01111 1.1e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
KDIFEGBE_01112 7e-242 S the current gene model (or a revised gene model) may contain a frame shift
KDIFEGBE_01113 3.4e-186 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
KDIFEGBE_01114 4.2e-195 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KDIFEGBE_01115 1.5e-153 czcD P cation diffusion facilitator family transporter
KDIFEGBE_01116 6e-94 K Transcriptional regulator, TetR family
KDIFEGBE_01117 3.1e-70 S Protein of unknown function with HXXEE motif
KDIFEGBE_01118 4.2e-45
KDIFEGBE_01119 5.7e-48 L Transposase
KDIFEGBE_01120 1.2e-272 S Signal peptide protein, YSIRK family
KDIFEGBE_01121 3.1e-127 K response regulator
KDIFEGBE_01122 1.4e-176 saeS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KDIFEGBE_01123 3.4e-104 L Transposase
KDIFEGBE_01124 5.2e-150 cbiO2 P Zeta toxin
KDIFEGBE_01125 3.5e-157 P abc transporter atp-binding protein
KDIFEGBE_01126 1.3e-132 cbiQ P Cobalt transport protein
KDIFEGBE_01127 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
KDIFEGBE_01128 1.6e-143 S Phenazine biosynthesis protein
KDIFEGBE_01129 8.5e-108 magIII L Base excision DNA repair protein, HhH-GPD family
KDIFEGBE_01130 4e-260 proWX P ABC transporter
KDIFEGBE_01131 1.1e-127 proV E abc transporter atp-binding protein
KDIFEGBE_01132 6.3e-138 1.6.5.2 GM epimerase
KDIFEGBE_01133 1.1e-67 mgrA K Transcriptional regulator, MarR family
KDIFEGBE_01134 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KDIFEGBE_01135 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KDIFEGBE_01138 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KDIFEGBE_01140 2.4e-136 IQ Acetoin reductase
KDIFEGBE_01141 9.1e-44 pspE P Rhodanese-like protein
KDIFEGBE_01142 1.4e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KDIFEGBE_01143 2.9e-223 XK27_05470 E Methionine synthase
KDIFEGBE_01144 4.8e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KDIFEGBE_01145 1.1e-227 T PhoQ Sensor
KDIFEGBE_01146 5.1e-119 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KDIFEGBE_01147 1.4e-142 S TraX protein
KDIFEGBE_01149 2.8e-54 V ABC-2 family transporter protein
KDIFEGBE_01150 1.3e-82 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
KDIFEGBE_01151 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KDIFEGBE_01152 5e-156 dprA LU DNA protecting protein DprA
KDIFEGBE_01153 4e-162 GK ROK family
KDIFEGBE_01154 1.5e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KDIFEGBE_01155 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KDIFEGBE_01156 4e-127 K DNA-binding helix-turn-helix protein
KDIFEGBE_01157 2.7e-91 niaR S small molecule binding protein (contains 3H domain)
KDIFEGBE_01158 2.7e-86
KDIFEGBE_01159 2.9e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KDIFEGBE_01160 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KDIFEGBE_01161 7.7e-126 gntR1 K transcriptional
KDIFEGBE_01162 5.1e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KDIFEGBE_01163 1.4e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KDIFEGBE_01164 4.6e-188 adhP 1.1.1.1 C alcohol dehydrogenase
KDIFEGBE_01165 1.2e-45
KDIFEGBE_01166 5.8e-51
KDIFEGBE_01167 1.7e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KDIFEGBE_01168 5.1e-156 aatB ET ABC transporter substrate-binding protein
KDIFEGBE_01169 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
KDIFEGBE_01170 4e-105 artQ P ABC transporter (Permease
KDIFEGBE_01171 1.9e-58 phnA P Alkylphosphonate utilization operon protein PhnA
KDIFEGBE_01172 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KDIFEGBE_01173 8.4e-165 cpsY K Transcriptional regulator
KDIFEGBE_01174 3.5e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
KDIFEGBE_01175 6e-95 yeiH S Membrane
KDIFEGBE_01176 3.8e-65 yeiH S Membrane
KDIFEGBE_01178 3.4e-09
KDIFEGBE_01179 9.9e-291 adcA P Belongs to the bacterial solute-binding protein 9 family
KDIFEGBE_01180 9.3e-147 XK27_10720 D peptidase activity
KDIFEGBE_01181 3.9e-278 pepD E Dipeptidase
KDIFEGBE_01182 8.2e-160 whiA K May be required for sporulation
KDIFEGBE_01183 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KDIFEGBE_01184 4.5e-163 rapZ S Displays ATPase and GTPase activities
KDIFEGBE_01185 2.6e-135 yejC S cyclic nucleotide-binding protein
KDIFEGBE_01186 5.4e-183 D nuclear chromosome segregation
KDIFEGBE_01187 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KDIFEGBE_01188 9.3e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KDIFEGBE_01189 9.7e-82 queD 4.1.2.50, 4.2.3.12 H synthase
KDIFEGBE_01190 1.5e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KDIFEGBE_01191 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
KDIFEGBE_01192 2.8e-19
KDIFEGBE_01193 2.4e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KDIFEGBE_01194 1.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KDIFEGBE_01195 5.2e-81 ypmB S Protein conserved in bacteria
KDIFEGBE_01196 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KDIFEGBE_01197 1.2e-112 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KDIFEGBE_01198 3.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
KDIFEGBE_01199 1.7e-180 yufP S Belongs to the binding-protein-dependent transport system permease family
KDIFEGBE_01200 2.1e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KDIFEGBE_01201 3.2e-187 tcsA S membrane
KDIFEGBE_01202 6.3e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KDIFEGBE_01203 3.9e-108 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KDIFEGBE_01204 1.9e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KDIFEGBE_01205 9.2e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
KDIFEGBE_01206 6.8e-170 coaA 2.7.1.33 F Pantothenic acid kinase
KDIFEGBE_01207 1e-29 rpsT J Binds directly to 16S ribosomal RNA
KDIFEGBE_01208 6.6e-241 T PhoQ Sensor
KDIFEGBE_01209 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KDIFEGBE_01210 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KDIFEGBE_01211 9e-111 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
KDIFEGBE_01212 1.4e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KDIFEGBE_01213 7.8e-92 panT S ECF transporter, substrate-specific component
KDIFEGBE_01214 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KDIFEGBE_01215 5.3e-164 metF 1.5.1.20 E reductase
KDIFEGBE_01216 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KDIFEGBE_01218 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
KDIFEGBE_01219 0.0 3.6.3.8 P cation transport ATPase
KDIFEGBE_01220 1.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KDIFEGBE_01221 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KDIFEGBE_01222 2.5e-236 dltB M Membrane protein involved in D-alanine export
KDIFEGBE_01223 1.6e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KDIFEGBE_01224 0.0 XK27_10035 V abc transporter atp-binding protein
KDIFEGBE_01225 2.2e-291 yfiB1 V abc transporter atp-binding protein
KDIFEGBE_01226 1.1e-99 pvaA M lytic transglycosylase activity
KDIFEGBE_01227 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
KDIFEGBE_01228 5.1e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KDIFEGBE_01229 1.1e-98 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KDIFEGBE_01230 2.5e-139 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KDIFEGBE_01231 1.1e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KDIFEGBE_01232 7.8e-111 tdk 2.7.1.21 F thymidine kinase
KDIFEGBE_01233 2e-183 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KDIFEGBE_01234 5.4e-152 gst O Glutathione S-transferase
KDIFEGBE_01235 1e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
KDIFEGBE_01236 1.7e-173 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KDIFEGBE_01237 4.4e-45 rpmE2 J 50S ribosomal protein L31
KDIFEGBE_01238 6.1e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
KDIFEGBE_01239 3.2e-162 ypuA S secreted protein
KDIFEGBE_01240 3.7e-72 yaeR E COG0346 Lactoylglutathione lyase and related lyases
KDIFEGBE_01241 4.6e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
KDIFEGBE_01242 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KDIFEGBE_01243 9.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KDIFEGBE_01244 1.2e-255 noxE P NADH oxidase
KDIFEGBE_01245 1.1e-294 yfmM S abc transporter atp-binding protein
KDIFEGBE_01246 8e-83 XK27_01265 S ECF-type riboflavin transporter, S component
KDIFEGBE_01247 1.1e-153 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KDIFEGBE_01248 8.2e-85 S ECF-type riboflavin transporter, S component
KDIFEGBE_01250 3.3e-236 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KDIFEGBE_01251 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
KDIFEGBE_01253 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KDIFEGBE_01254 9.2e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KDIFEGBE_01255 1.5e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KDIFEGBE_01256 1.3e-22 WQ51_00220 K Helix-turn-helix domain
KDIFEGBE_01257 3.7e-91 S Protein of unknown function (DUF3278)
KDIFEGBE_01258 0.0 smc D Required for chromosome condensation and partitioning
KDIFEGBE_01259 2.7e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KDIFEGBE_01260 1.9e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KDIFEGBE_01261 2.8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KDIFEGBE_01262 8.8e-124 alkD L DNA alkylation repair enzyme
KDIFEGBE_01263 3.3e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KDIFEGBE_01264 5.2e-87 pat 2.3.1.183 M acetyltransferase
KDIFEGBE_01265 4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KDIFEGBE_01266 2.6e-152 L PFAM Integrase catalytic region
KDIFEGBE_01267 7.4e-278 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KDIFEGBE_01268 3.4e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KDIFEGBE_01269 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KDIFEGBE_01270 3.2e-98 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KDIFEGBE_01271 1.5e-18 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KDIFEGBE_01272 3e-119 sdaAB 4.3.1.17 E L-serine dehydratase
KDIFEGBE_01273 5.8e-147 sdaAA 4.3.1.17 E L-serine dehydratase
KDIFEGBE_01274 7.3e-124 tktC 2.2.1.1 G Transketolase, pyrimidine binding domain
KDIFEGBE_01275 4e-124 tktN 2.2.1.1 G Transketolase
KDIFEGBE_01276 1.4e-219 ulaA 2.7.1.194 S PTS system sugar-specific permease component
KDIFEGBE_01277 3.7e-42 ulaB 2.7.1.194 G COG3414 Phosphotransferase system galactitol-specific IIB component
KDIFEGBE_01278 8e-224 2.7.1.194, 2.7.1.202, 2.7.1.204 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KDIFEGBE_01279 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
KDIFEGBE_01280 1.9e-133 L Integrase
KDIFEGBE_01281 2e-202 S Protein of unknown function DUF262
KDIFEGBE_01282 2.1e-151 S Protein of unknown function DUF262
KDIFEGBE_01283 3.8e-78 mutT 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KDIFEGBE_01284 1.4e-79 3.4.21.89 S RDD family
KDIFEGBE_01285 2.1e-147 K sequence-specific DNA binding
KDIFEGBE_01286 1e-148 V ABC transporter, ATP-binding protein
KDIFEGBE_01287 8.6e-96 S ABC-2 family transporter protein
KDIFEGBE_01288 2.5e-132 K sequence-specific DNA binding
KDIFEGBE_01289 5.9e-46
KDIFEGBE_01290 2.7e-86
KDIFEGBE_01291 1.3e-76 K Acetyltransferase (GNAT) domain
KDIFEGBE_01292 1.9e-141 S ABC-2 family transporter protein
KDIFEGBE_01293 5.3e-142 S ABC-2 family transporter protein
KDIFEGBE_01294 1.5e-186 S abc transporter atp-binding protein
KDIFEGBE_01295 3.3e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KDIFEGBE_01296 3.8e-188 desK 2.7.13.3 T Histidine kinase
KDIFEGBE_01297 9.9e-132 yvfS V ABC-2 type transporter
KDIFEGBE_01298 1.9e-158 XK27_09825 V 'abc transporter, ATP-binding protein
KDIFEGBE_01302 2.3e-195 anK3 G response to abiotic stimulus
KDIFEGBE_01303 0.0 hscC O Belongs to the heat shock protein 70 family
KDIFEGBE_01304 1.9e-164 yocS S Transporter
KDIFEGBE_01305 1.8e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
KDIFEGBE_01306 9.9e-132 yvfS V Transporter
KDIFEGBE_01307 1.7e-154 XK27_09825 V abc transporter atp-binding protein
KDIFEGBE_01308 8.8e-18 liaI KT membrane
KDIFEGBE_01309 3.6e-32 liaI KT membrane
KDIFEGBE_01310 6.1e-93 XK27_05000 S metal cluster binding
KDIFEGBE_01311 0.0 V ABC transporter (permease)
KDIFEGBE_01312 4.6e-132 macB2 V ABC transporter, ATP-binding protein
KDIFEGBE_01313 2.6e-164 T Histidine kinase
KDIFEGBE_01314 1.2e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KDIFEGBE_01315 4.3e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KDIFEGBE_01316 1.2e-222 pbuX F xanthine permease
KDIFEGBE_01317 2.2e-277 V (ABC) transporter
KDIFEGBE_01318 3.7e-143 K sequence-specific DNA binding
KDIFEGBE_01319 5.1e-243 norM V Multidrug efflux pump
KDIFEGBE_01321 3e-181 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KDIFEGBE_01322 2.3e-227 brnQ E Component of the transport system for branched-chain amino acids
KDIFEGBE_01323 1.7e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
KDIFEGBE_01324 2e-58 S Protein of unknown function (DUF3290)
KDIFEGBE_01325 2.8e-106 S Protein of unknown function (DUF421)
KDIFEGBE_01326 1.4e-16 csbD S CsbD-like
KDIFEGBE_01327 1.7e-104 S Carbohydrate-binding domain-containing protein Cthe_2159
KDIFEGBE_01328 6.8e-51 XK27_01300 P Protein conserved in bacteria
KDIFEGBE_01329 1.1e-213 yfnA E amino acid
KDIFEGBE_01330 0.0 S dextransucrase activity
KDIFEGBE_01331 5.8e-59 M Putative cell wall binding repeat
KDIFEGBE_01333 4.8e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
KDIFEGBE_01334 1.9e-113 yxeN P ABC transporter, permease protein
KDIFEGBE_01335 9.1e-111 ytmL P ABC transporter (Permease
KDIFEGBE_01336 4.7e-165 ET ABC transporter substrate-binding protein
KDIFEGBE_01337 3.6e-177 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
KDIFEGBE_01338 6.6e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KDIFEGBE_01339 1.5e-42 S Sugar efflux transporter for intercellular exchange
KDIFEGBE_01340 3e-204 P FtsX-like permease family
KDIFEGBE_01341 6e-123 V abc transporter atp-binding protein
KDIFEGBE_01342 1.1e-96 K WHG domain
KDIFEGBE_01343 7.5e-169 ydhF S Aldo keto reductase
KDIFEGBE_01344 4.8e-07 S Protein of unknown function (DUF3169)
KDIFEGBE_01345 2.5e-27 XK27_07105 K transcriptional
KDIFEGBE_01346 2.8e-35
KDIFEGBE_01347 8.7e-110 XK27_02070 S nitroreductase
KDIFEGBE_01348 1.2e-147 1.13.11.2 S glyoxalase
KDIFEGBE_01349 2.6e-74 ywnA K Transcriptional regulator
KDIFEGBE_01350 1.1e-153 E Alpha/beta hydrolase of unknown function (DUF915)
KDIFEGBE_01351 1.9e-226 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KDIFEGBE_01352 5.3e-167 bcrA V abc transporter atp-binding protein
KDIFEGBE_01353 2e-127 S ABC-2 family transporter protein
KDIFEGBE_01354 5.9e-147 T PhoQ Sensor
KDIFEGBE_01355 4.9e-125 T Xre family transcriptional regulator
KDIFEGBE_01356 3.5e-109 drgA C nitroreductase
KDIFEGBE_01357 3.5e-66 yoaK S Protein of unknown function (DUF1275)
KDIFEGBE_01358 2.9e-31 yoaK S Protein of unknown function (DUF1275)
KDIFEGBE_01359 4.5e-39 DJ nuclease activity
KDIFEGBE_01360 4.2e-30 XK27_10490
KDIFEGBE_01361 1.3e-156 yvgN C reductase
KDIFEGBE_01362 6.5e-210 S Tetratricopeptide repeat
KDIFEGBE_01363 0.0 lacL 3.2.1.23 G -beta-galactosidase
KDIFEGBE_01364 0.0 lacS G transporter
KDIFEGBE_01365 1e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KDIFEGBE_01366 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KDIFEGBE_01367 6.6e-284 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KDIFEGBE_01368 2.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KDIFEGBE_01369 1.4e-181 galR K Transcriptional regulator
KDIFEGBE_01370 1.1e-305 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
KDIFEGBE_01371 1.3e-160 gtfA 2.4.1.329, 2.4.1.7 GH13 G Sucrose glucosyltransferase
KDIFEGBE_01372 2.8e-199 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
KDIFEGBE_01373 7.2e-218 vncS 2.7.13.3 T Histidine kinase
KDIFEGBE_01374 5.2e-116 K Response regulator receiver domain protein
KDIFEGBE_01375 2.2e-233 vex3 V Efflux ABC transporter, permease protein
KDIFEGBE_01376 6.6e-108 vex2 V abc transporter atp-binding protein
KDIFEGBE_01377 2.8e-211 vex1 V Efflux ABC transporter, permease protein
KDIFEGBE_01378 1.9e-283 XK27_07020 S Belongs to the UPF0371 family
KDIFEGBE_01380 1.4e-195 gldA 1.1.1.6 C glycerol dehydrogenase
KDIFEGBE_01381 1.8e-176 XK27_10475 S oxidoreductase
KDIFEGBE_01382 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
KDIFEGBE_01383 3.8e-94 dhaL 2.7.1.121 S Dihydroxyacetone kinase
KDIFEGBE_01384 1.4e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
KDIFEGBE_01385 3.7e-227 thrE K Psort location CytoplasmicMembrane, score
KDIFEGBE_01386 0.0 M Putative cell wall binding repeat
KDIFEGBE_01387 1.6e-33 S Immunity protein 41
KDIFEGBE_01388 0.0 pepO 3.4.24.71 O Peptidase family M13
KDIFEGBE_01389 1.8e-08 S Enterocin A Immunity
KDIFEGBE_01390 1.1e-192 mccF V LD-carboxypeptidase
KDIFEGBE_01391 2.7e-15 S integral membrane protein
KDIFEGBE_01392 4.2e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
KDIFEGBE_01393 1.4e-109 yhfC S Putative membrane peptidase family (DUF2324)
KDIFEGBE_01394 3.4e-49 3.6.1.55 F NUDIX domain
KDIFEGBE_01396 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KDIFEGBE_01398 1.1e-244 S dextransucrase activity
KDIFEGBE_01399 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KDIFEGBE_01400 6.7e-92 M Putative cell wall binding repeat
KDIFEGBE_01401 2.5e-240 M Putative cell wall binding repeat
KDIFEGBE_01402 1.1e-222 S dextransucrase activity
KDIFEGBE_01403 0.0 S dextransucrase activity
KDIFEGBE_01404 2.9e-90 S dextransucrase activity
KDIFEGBE_01405 0.0 S dextransucrase activity
KDIFEGBE_01406 5.5e-63
KDIFEGBE_01407 7.3e-101 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KDIFEGBE_01408 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KDIFEGBE_01409 0.0 M Putative cell wall binding repeat
KDIFEGBE_01410 0.0 M Putative cell wall binding repeat
KDIFEGBE_01411 0.0 M Putative cell wall binding repeat
KDIFEGBE_01412 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KDIFEGBE_01413 2.2e-82 comFC S Competence protein
KDIFEGBE_01414 2.1e-249 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KDIFEGBE_01415 2.9e-108 yvyE 3.4.13.9 S YigZ family
KDIFEGBE_01416 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KDIFEGBE_01417 4.6e-112 acuB S CBS domain
KDIFEGBE_01418 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KDIFEGBE_01419 1.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KDIFEGBE_01420 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
KDIFEGBE_01421 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
KDIFEGBE_01422 7e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KDIFEGBE_01423 5.4e-46 ylbG S UPF0298 protein
KDIFEGBE_01424 9.2e-72 ylbF S Belongs to the UPF0342 family
KDIFEGBE_01425 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KDIFEGBE_01426 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KDIFEGBE_01427 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
KDIFEGBE_01428 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
KDIFEGBE_01429 3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KDIFEGBE_01430 2.6e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
KDIFEGBE_01431 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
KDIFEGBE_01432 2.9e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
KDIFEGBE_01433 1.7e-268 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KDIFEGBE_01434 1.7e-99 yvdD 3.2.2.10 S Belongs to the LOG family
KDIFEGBE_01435 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KDIFEGBE_01436 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KDIFEGBE_01437 8e-42 ylxQ J ribosomal protein
KDIFEGBE_01438 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
KDIFEGBE_01439 1.6e-195 nusA K Participates in both transcription termination and antitermination
KDIFEGBE_01440 6.7e-81 rimP S Required for maturation of 30S ribosomal subunits
KDIFEGBE_01441 4.4e-188 brpA K Transcriptional
KDIFEGBE_01442 8.7e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
KDIFEGBE_01443 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
KDIFEGBE_01444 1.2e-247 pbuO S permease
KDIFEGBE_01445 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KDIFEGBE_01446 5.4e-61 agrA KT LytTr DNA-binding domain
KDIFEGBE_01447 7.2e-96 blpH 2.7.13.3 T protein histidine kinase activity
KDIFEGBE_01448 1.3e-100 mesE M Transport protein ComB
KDIFEGBE_01449 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KDIFEGBE_01450 6.5e-10
KDIFEGBE_01451 1.1e-48 blpT
KDIFEGBE_01452 1.3e-23 L Transposase
KDIFEGBE_01453 3.5e-137 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
KDIFEGBE_01454 6.2e-169 manL 2.7.1.191 G pts system
KDIFEGBE_01455 3.4e-133 manY G pts system
KDIFEGBE_01456 6.7e-162 manN G PTS system mannose fructose sorbose family IID component
KDIFEGBE_01457 1e-66 manO S Protein conserved in bacteria
KDIFEGBE_01458 6.3e-174 manL 2.7.1.191 G pts system
KDIFEGBE_01459 2e-117 manM G pts system
KDIFEGBE_01460 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
KDIFEGBE_01461 2.5e-62 manO S protein conserved in bacteria
KDIFEGBE_01462 3.1e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KDIFEGBE_01463 4.8e-111
KDIFEGBE_01464 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KDIFEGBE_01465 4.4e-166 dnaI L Primosomal protein DnaI
KDIFEGBE_01466 8.8e-215 dnaB L Replication initiation and membrane attachment
KDIFEGBE_01467 3.6e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KDIFEGBE_01468 5.9e-280 T PhoQ Sensor
KDIFEGBE_01469 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KDIFEGBE_01470 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
KDIFEGBE_01471 1.2e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
KDIFEGBE_01472 2e-234 P COG0168 Trk-type K transport systems, membrane components
KDIFEGBE_01473 3.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
KDIFEGBE_01474 2e-149 cbiQ P cobalt transport
KDIFEGBE_01475 1.9e-308 ykoD P abc transporter atp-binding protein
KDIFEGBE_01476 2.3e-93 S UPF0397 protein
KDIFEGBE_01477 3.5e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KDIFEGBE_01478 5.1e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KDIFEGBE_01479 1.2e-99 metI P ABC transporter (Permease
KDIFEGBE_01480 1.7e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KDIFEGBE_01481 4.5e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KDIFEGBE_01482 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
KDIFEGBE_01483 6.3e-138 ET ABC transporter substrate-binding protein
KDIFEGBE_01484 2.8e-252 S Domain of unknown function (DUF4173)
KDIFEGBE_01485 1.3e-54 yhaI L Membrane
KDIFEGBE_01486 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KDIFEGBE_01487 2.3e-154 K sequence-specific DNA binding
KDIFEGBE_01488 1.4e-100 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
KDIFEGBE_01489 6e-89 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KDIFEGBE_01490 1.1e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KDIFEGBE_01491 1.2e-244 trkA P Potassium transporter peripheral membrane component
KDIFEGBE_01492 1.8e-257 trkH P Cation transport protein
KDIFEGBE_01493 1.8e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
KDIFEGBE_01494 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KDIFEGBE_01495 1.2e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KDIFEGBE_01496 3.4e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KDIFEGBE_01497 1e-126 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KDIFEGBE_01498 2.7e-85 ykuL S CBS domain
KDIFEGBE_01499 1.6e-96 XK27_09740 S Phosphoesterase
KDIFEGBE_01500 1.1e-181 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KDIFEGBE_01501 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KDIFEGBE_01502 1.6e-36 yneF S UPF0154 protein
KDIFEGBE_01503 4.1e-90 K transcriptional regulator
KDIFEGBE_01504 6.9e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KDIFEGBE_01505 4.2e-12 ycdA S Domain of unknown function (DUF4352)
KDIFEGBE_01506 4.8e-96 ybhL S Belongs to the BI1 family
KDIFEGBE_01507 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
KDIFEGBE_01508 3.9e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KDIFEGBE_01509 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KDIFEGBE_01510 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KDIFEGBE_01511 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KDIFEGBE_01512 1.7e-303 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KDIFEGBE_01513 3.2e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
KDIFEGBE_01514 1.2e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KDIFEGBE_01515 9.6e-23
KDIFEGBE_01516 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KDIFEGBE_01517 7.5e-275 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KDIFEGBE_01518 9.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KDIFEGBE_01519 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KDIFEGBE_01520 5.2e-95 ypsA S Belongs to the UPF0398 family
KDIFEGBE_01521 4.8e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KDIFEGBE_01522 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KDIFEGBE_01523 1.3e-254 pepC 3.4.22.40 E aminopeptidase
KDIFEGBE_01524 2e-74 yhaI S Protein of unknown function (DUF805)
KDIFEGBE_01525 2.9e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KDIFEGBE_01526 1.6e-271 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KDIFEGBE_01527 7.9e-217 macB_2 V FtsX-like permease family
KDIFEGBE_01528 4.7e-120 yhcA V abc transporter atp-binding protein
KDIFEGBE_01529 9.6e-124 mta K Transcriptional
KDIFEGBE_01530 8.9e-32 S Protein of unknown function (DUF3021)
KDIFEGBE_01531 7.6e-74 K COG3279 Response regulator of the LytR AlgR family
KDIFEGBE_01532 3.4e-128 cylB V ABC-2 type transporter
KDIFEGBE_01533 6e-152 cylA V abc transporter atp-binding protein
KDIFEGBE_01534 2.5e-231 S COG1073 Hydrolases of the alpha beta superfamily
KDIFEGBE_01535 5.8e-74 K helix_turn_helix multiple antibiotic resistance protein
KDIFEGBE_01536 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KDIFEGBE_01537 3.6e-132 glcR K transcriptional regulator (DeoR family)
KDIFEGBE_01538 2.7e-146 cof S Sucrose-6F-phosphate phosphohydrolase
KDIFEGBE_01539 1.4e-67 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
KDIFEGBE_01540 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
KDIFEGBE_01541 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
KDIFEGBE_01542 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KDIFEGBE_01543 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KDIFEGBE_01544 1.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KDIFEGBE_01545 5.8e-55 S TM2 domain
KDIFEGBE_01546 1.9e-44
KDIFEGBE_01548 2.4e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KDIFEGBE_01549 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KDIFEGBE_01550 1.4e-142 cmpC S abc transporter atp-binding protein
KDIFEGBE_01551 0.0 WQ51_06230 S ABC transporter
KDIFEGBE_01552 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KDIFEGBE_01553 3e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KDIFEGBE_01554 9.3e-144 cdsA 2.7.7.41 S Belongs to the CDS family
KDIFEGBE_01555 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KDIFEGBE_01556 1.7e-46 yajC U protein transport
KDIFEGBE_01557 6.1e-126 yeeN K transcriptional regulatory protein
KDIFEGBE_01558 2.3e-271 V ABC transporter
KDIFEGBE_01559 1.4e-153 Z012_04635 K sequence-specific DNA binding
KDIFEGBE_01560 2.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
KDIFEGBE_01561 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KDIFEGBE_01562 1.1e-108 L Transposase IS116 IS110 IS902
KDIFEGBE_01563 9.2e-59 L MULE transposase domain
KDIFEGBE_01564 8.1e-16 tnp* L An automated process has identified a potential problem with this gene model
KDIFEGBE_01565 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
KDIFEGBE_01566 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
KDIFEGBE_01567 1.1e-95 srlA G PTS system glucitol sorbitol-specific
KDIFEGBE_01568 6.8e-84 gutM K phosphoenolpyruvate-dependent sugar phosphotransferase system
KDIFEGBE_01569 0.0 srlM 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
KDIFEGBE_01570 1.4e-142 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KDIFEGBE_01571 4.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
KDIFEGBE_01572 4.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
KDIFEGBE_01573 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KDIFEGBE_01574 5.5e-159 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KDIFEGBE_01575 1.9e-128 adcB P ABC transporter (Permease
KDIFEGBE_01576 7.1e-135 adcC P ABC transporter, ATP-binding protein
KDIFEGBE_01577 1e-70 adcR K transcriptional
KDIFEGBE_01578 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KDIFEGBE_01579 5.2e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KDIFEGBE_01580 2.7e-26
KDIFEGBE_01581 2.9e-273 sufB O assembly protein SufB
KDIFEGBE_01582 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
KDIFEGBE_01583 2.8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KDIFEGBE_01584 1.2e-233 sufD O assembly protein SufD
KDIFEGBE_01585 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KDIFEGBE_01586 7.4e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
KDIFEGBE_01587 1.6e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KDIFEGBE_01588 6.3e-18 S Protein of unknown function (DUF3021)
KDIFEGBE_01589 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KDIFEGBE_01590 7.9e-272 glnP P ABC transporter
KDIFEGBE_01591 2.2e-123 glnQ E abc transporter atp-binding protein
KDIFEGBE_01592 2.1e-184 D nuclear chromosome segregation
KDIFEGBE_01593 1.2e-71 V VanZ like family
KDIFEGBE_01594 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KDIFEGBE_01595 2.1e-192 yhjX P Major Facilitator
KDIFEGBE_01596 1.3e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KDIFEGBE_01597 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KDIFEGBE_01598 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KDIFEGBE_01599 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KDIFEGBE_01600 4.4e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KDIFEGBE_01601 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KDIFEGBE_01602 4.1e-83 nrdI F Belongs to the NrdI family
KDIFEGBE_01603 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KDIFEGBE_01604 6.5e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KDIFEGBE_01605 1e-176 prmA J Ribosomal protein L11 methyltransferase
KDIFEGBE_01606 1.9e-75 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
KDIFEGBE_01607 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
KDIFEGBE_01608 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KDIFEGBE_01609 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KDIFEGBE_01610 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KDIFEGBE_01611 5.8e-138 ykuT M mechanosensitive ion channel
KDIFEGBE_01612 4.3e-86 sigH K DNA-templated transcription, initiation
KDIFEGBE_01614 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KDIFEGBE_01615 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KDIFEGBE_01616 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KDIFEGBE_01617 4.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KDIFEGBE_01618 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KDIFEGBE_01619 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
KDIFEGBE_01620 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
KDIFEGBE_01621 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KDIFEGBE_01622 1.2e-302 yloV S kinase related to dihydroxyacetone kinase
KDIFEGBE_01623 1.4e-57 asp S cog cog1302
KDIFEGBE_01624 2.1e-225 norN V Mate efflux family protein
KDIFEGBE_01625 2.7e-277 thrC 4.2.3.1 E Threonine synthase
KDIFEGBE_01628 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KDIFEGBE_01629 0.0 pepO 3.4.24.71 O Peptidase family M13
KDIFEGBE_01630 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KDIFEGBE_01631 4.7e-290 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KDIFEGBE_01632 3.9e-125 treR K trehalose operon
KDIFEGBE_01633 3.1e-93 ywlG S Belongs to the UPF0340 family
KDIFEGBE_01636 2e-166 lacX G Aldose 1-epimerase
KDIFEGBE_01637 1.5e-285 lacG 3.2.1.85 G Glycosyl hydrolase family 1
KDIFEGBE_01638 0.0 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
KDIFEGBE_01639 2.4e-50 lacF 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
KDIFEGBE_01640 1e-179 lacD 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
KDIFEGBE_01641 1.3e-93 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
KDIFEGBE_01642 6.7e-72 lacA 5.3.1.26 G Ribose/Galactose Isomerase
KDIFEGBE_01643 1.7e-110 lacR K DeoR C terminal sensor domain
KDIFEGBE_01644 2.6e-79 S Haloacid dehalogenase-like hydrolase
KDIFEGBE_01645 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
KDIFEGBE_01647 6e-241 6.3.2.2 H gamma-glutamylcysteine synthetase
KDIFEGBE_01648 4.4e-62 rplQ J ribosomal protein l17
KDIFEGBE_01649 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KDIFEGBE_01650 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KDIFEGBE_01651 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KDIFEGBE_01652 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KDIFEGBE_01653 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KDIFEGBE_01654 6.2e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KDIFEGBE_01655 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KDIFEGBE_01656 5.7e-58 rplO J binds to the 23S rRNA
KDIFEGBE_01657 1.9e-23 rpmD J ribosomal protein l30
KDIFEGBE_01658 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KDIFEGBE_01659 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KDIFEGBE_01660 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KDIFEGBE_01661 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KDIFEGBE_01662 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KDIFEGBE_01663 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KDIFEGBE_01664 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KDIFEGBE_01665 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KDIFEGBE_01666 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KDIFEGBE_01667 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KDIFEGBE_01668 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KDIFEGBE_01669 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KDIFEGBE_01670 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KDIFEGBE_01671 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KDIFEGBE_01672 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KDIFEGBE_01673 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KDIFEGBE_01674 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
KDIFEGBE_01675 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KDIFEGBE_01676 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
KDIFEGBE_01677 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KDIFEGBE_01678 0.0 XK27_09800 I Acyltransferase
KDIFEGBE_01679 2.8e-35 XK27_09805 S MORN repeat protein
KDIFEGBE_01680 2.6e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KDIFEGBE_01681 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KDIFEGBE_01682 5e-90 adk 2.7.4.3 F topology modulation protein
KDIFEGBE_01684 4.9e-174 yeiH S membrane
KDIFEGBE_01685 5.6e-81 S Short repeat of unknown function (DUF308)
KDIFEGBE_01686 8e-88 K TRANSCRIPTIONal
KDIFEGBE_01687 2.8e-144 L Replication initiation factor
KDIFEGBE_01688 1.9e-18 S Domain of unknown function (DUF3173)
KDIFEGBE_01689 2.9e-215 int L Belongs to the 'phage' integrase family
KDIFEGBE_01691 1.8e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
KDIFEGBE_01692 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KDIFEGBE_01693 6.3e-44 yrzL S Belongs to the UPF0297 family
KDIFEGBE_01694 2.3e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KDIFEGBE_01695 3.2e-44 yrzB S Belongs to the UPF0473 family
KDIFEGBE_01696 4.4e-297 ccs S the current gene model (or a revised gene model) may contain a frame shift
KDIFEGBE_01697 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KDIFEGBE_01698 7.5e-14
KDIFEGBE_01699 1.9e-89 XK27_10930 K acetyltransferase
KDIFEGBE_01700 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KDIFEGBE_01701 3.6e-123 yaaA S Belongs to the UPF0246 family
KDIFEGBE_01702 3.2e-167 XK27_01785 S cog cog1284
KDIFEGBE_01703 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KDIFEGBE_01705 1.9e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
KDIFEGBE_01706 4.1e-75 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KDIFEGBE_01707 9.2e-102 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KDIFEGBE_01708 1.2e-218 metE 2.1.1.14 E Methionine synthase
KDIFEGBE_01709 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KDIFEGBE_01710 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KDIFEGBE_01711 4.3e-127 P ATPases associated with a variety of cellular activities
KDIFEGBE_01712 7.4e-231
KDIFEGBE_01713 5.2e-281 L DNA integration
KDIFEGBE_01715 1e-198 L Replication initiation factor
KDIFEGBE_01716 5.4e-61
KDIFEGBE_01717 2e-13
KDIFEGBE_01719 2.9e-64
KDIFEGBE_01720 7e-262 mloB K Transcriptional regulator
KDIFEGBE_01721 2.9e-218 KLT Protein tyrosine kinase
KDIFEGBE_01722 3e-62 tnp* 1.1.1.193 L An automated process has identified a potential problem with this gene model
KDIFEGBE_01723 4.5e-186 L Transposase
KDIFEGBE_01724 1.5e-60 fruR K transcriptional
KDIFEGBE_01725 4.3e-36 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KDIFEGBE_01726 5.8e-162 T Diguanylate cyclase
KDIFEGBE_01728 2.2e-148 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KDIFEGBE_01729 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
KDIFEGBE_01730 0.0
KDIFEGBE_01734 1.8e-115 nudL L hydrolase
KDIFEGBE_01735 1.6e-52 K transcriptional regulator, PadR family
KDIFEGBE_01736 1e-70 XK27_06920 S Protein of unknown function (DUF1700)
KDIFEGBE_01737 1.1e-105 S Putative adhesin
KDIFEGBE_01738 1.6e-159 XK27_06930 V domain protein
KDIFEGBE_01739 1.9e-95 XK27_06935 K transcriptional regulator
KDIFEGBE_01740 4.1e-54 ypaA M Membrane
KDIFEGBE_01741 1.9e-10
KDIFEGBE_01742 7.1e-124
KDIFEGBE_01743 9.6e-08
KDIFEGBE_01744 2.6e-173 L virion core protein, lumpy skin disease virus
KDIFEGBE_01745 1.2e-74
KDIFEGBE_01746 7.5e-16
KDIFEGBE_01748 3.5e-09
KDIFEGBE_01749 3.1e-81 K Transcriptional
KDIFEGBE_01750 5.7e-182 sip L Phage integrase, N-terminal SAM-like domain
KDIFEGBE_01751 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KDIFEGBE_01752 1.8e-47 veg S Biofilm formation stimulator VEG
KDIFEGBE_01753 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KDIFEGBE_01754 2.2e-73 rplI J binds to the 23S rRNA
KDIFEGBE_01755 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KDIFEGBE_01756 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KDIFEGBE_01757 5.4e-99 yvbG U UPF0056 membrane protein
KDIFEGBE_01758 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KDIFEGBE_01759 0.0 S Bacterial membrane protein, YfhO
KDIFEGBE_01760 8.4e-64 isaA GH23 M Immunodominant staphylococcal antigen A
KDIFEGBE_01761 1e-70 lytE M LysM domain protein
KDIFEGBE_01762 2.8e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KDIFEGBE_01763 6.2e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KDIFEGBE_01764 1.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KDIFEGBE_01765 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KDIFEGBE_01766 1.4e-129 S sequence-specific DNA binding
KDIFEGBE_01767 5.9e-233 ymfH S Peptidase M16
KDIFEGBE_01768 3.5e-230 ymfF S Peptidase M16
KDIFEGBE_01769 4.9e-58 yaaA S S4 domain protein YaaA
KDIFEGBE_01770 5.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KDIFEGBE_01771 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KDIFEGBE_01772 4.5e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KDIFEGBE_01773 7.1e-153 yvjA S membrane
KDIFEGBE_01774 3.3e-305 ybiT S abc transporter atp-binding protein
KDIFEGBE_01775 0.0 XK27_10405 S Bacterial membrane protein YfhO
KDIFEGBE_01779 6.2e-120 yoaK S Protein of unknown function (DUF1275)
KDIFEGBE_01780 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KDIFEGBE_01781 5.1e-205 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KDIFEGBE_01782 1.4e-133 parB K Belongs to the ParB family
KDIFEGBE_01783 1.3e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KDIFEGBE_01784 2.7e-197 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KDIFEGBE_01785 1.1e-29 yyzM S Protein conserved in bacteria
KDIFEGBE_01786 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KDIFEGBE_01787 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KDIFEGBE_01788 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KDIFEGBE_01789 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KDIFEGBE_01790 3e-60 divIC D Septum formation initiator
KDIFEGBE_01792 1.7e-235 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
KDIFEGBE_01793 5.3e-234 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KDIFEGBE_01794 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KDIFEGBE_01795 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KDIFEGBE_01796 5.3e-95 XK27_05505 S Psort location CytoplasmicMembrane, score
KDIFEGBE_01797 3.5e-143 P molecular chaperone
KDIFEGBE_01798 1.6e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
KDIFEGBE_01799 7.5e-178 XK27_08075 M glycosyl transferase family 2
KDIFEGBE_01800 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KDIFEGBE_01801 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KDIFEGBE_01802 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KDIFEGBE_01803 7.6e-229 rodA D Belongs to the SEDS family
KDIFEGBE_01804 6.6e-221 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KDIFEGBE_01805 1.5e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KDIFEGBE_01806 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KDIFEGBE_01807 2.4e-136 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KDIFEGBE_01808 1.1e-19 Q Methyltransferase domain
KDIFEGBE_01809 3.1e-66 GnaT 2.5.1.16 K acetyltransferase
KDIFEGBE_01810 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
KDIFEGBE_01811 4.9e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KDIFEGBE_01812 1.1e-180 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KDIFEGBE_01813 7.2e-124 dnaD
KDIFEGBE_01814 3.8e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KDIFEGBE_01816 8.9e-232 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KDIFEGBE_01817 1.3e-28 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KDIFEGBE_01818 6.9e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KDIFEGBE_01819 1.5e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KDIFEGBE_01820 3.7e-73 argR K Regulates arginine biosynthesis genes
KDIFEGBE_01821 2.5e-300 recN L May be involved in recombinational repair of damaged DNA
KDIFEGBE_01822 1.3e-143 DegV S DegV family
KDIFEGBE_01823 2.8e-157 ypmR E COG2755 Lysophospholipase L1 and related esterases
KDIFEGBE_01824 1.3e-94 ypmS S Protein conserved in bacteria
KDIFEGBE_01825 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KDIFEGBE_01827 1.4e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
KDIFEGBE_01828 6.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KDIFEGBE_01829 5.4e-53 hxlR K HxlR-like helix-turn-helix
KDIFEGBE_01830 2e-70 S SnoaL-like polyketide cyclase
KDIFEGBE_01831 1.4e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KDIFEGBE_01832 8.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KDIFEGBE_01833 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KDIFEGBE_01834 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KDIFEGBE_01835 0.0 dnaE 2.7.7.7 L DNA polymerase
KDIFEGBE_01836 8.8e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KDIFEGBE_01837 3.9e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KDIFEGBE_01838 1.9e-234 Q the current gene model (or a revised gene model) may contain a frame shift
KDIFEGBE_01839 1.7e-18 S Domain of unknown function (DUF4649)
KDIFEGBE_01840 4e-176 XK27_08835 S ABC transporter substrate binding protein
KDIFEGBE_01841 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
KDIFEGBE_01842 3.1e-136 XK27_08845 S abc transporter atp-binding protein
KDIFEGBE_01843 2.1e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KDIFEGBE_01844 2.5e-149 estA CE1 S Esterase
KDIFEGBE_01845 3.9e-125 XK27_08875 O Zinc-dependent metalloprotease
KDIFEGBE_01846 5.7e-19 XK27_08880
KDIFEGBE_01847 1e-75 fld C Flavodoxin
KDIFEGBE_01848 2.7e-280 clcA P Chloride transporter, ClC family
KDIFEGBE_01849 1.9e-40 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
KDIFEGBE_01850 5.4e-215 XK27_05110 P Chloride transporter ClC family
KDIFEGBE_01851 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KDIFEGBE_01854 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
KDIFEGBE_01855 6.5e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KDIFEGBE_01856 2.3e-87 ytsP 1.8.4.14 T GAF domain-containing protein
KDIFEGBE_01857 2e-297 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KDIFEGBE_01858 1.6e-171 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KDIFEGBE_01859 1.2e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KDIFEGBE_01860 1e-275 5.1.3.2 GM Psort location CytoplasmicMembrane, score
KDIFEGBE_01861 5.7e-145
KDIFEGBE_01862 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
KDIFEGBE_01863 2.4e-267 pelF GT4 M Domain of unknown function (DUF3492)
KDIFEGBE_01864 4.2e-182 pelG M Putative exopolysaccharide Exporter (EPS-E)
KDIFEGBE_01865 2.2e-222 cotH M CotH kinase protein
KDIFEGBE_01866 8.7e-96 P VTC domain
KDIFEGBE_01867 5.4e-84 S membrane
KDIFEGBE_01868 2e-133 G Domain of unknown function (DUF4832)
KDIFEGBE_01869 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KDIFEGBE_01870 3.7e-11 S Protein of unknown function (DUF1146)
KDIFEGBE_01871 5e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KDIFEGBE_01872 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
KDIFEGBE_01873 4.6e-152 endA F DNA RNA non-specific endonuclease
KDIFEGBE_01874 1.6e-27 bipA S protein secretion
KDIFEGBE_01875 2.7e-24 L the current gene model (or a revised gene model) may contain a frame shift
KDIFEGBE_01876 1.2e-92 L Transposase
KDIFEGBE_01877 1.5e-30 L PFAM transposase IS116 IS110 IS902 family
KDIFEGBE_01878 0.0 zmpB M signal peptide protein, YSIRK family
KDIFEGBE_01879 0.0 GM domain, Protein
KDIFEGBE_01880 1.3e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KDIFEGBE_01881 0.0 sbcC L ATPase involved in DNA repair
KDIFEGBE_01882 0.0 M family 8
KDIFEGBE_01883 1.6e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
KDIFEGBE_01884 9.4e-289 asp1 S Accessory Sec system protein Asp1
KDIFEGBE_01885 3.1e-292 asp2 3.4.11.5 S Accessory Sec system protein Asp2
KDIFEGBE_01886 1.1e-77 asp3 S Accessory Sec system protein Asp3
KDIFEGBE_01887 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KDIFEGBE_01888 4.5e-280 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KDIFEGBE_01889 3e-243 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KDIFEGBE_01890 2.6e-17 S Accessory secretory protein Sec Asp4
KDIFEGBE_01891 3.6e-16 S Accessory secretory protein Sec, Asp5
KDIFEGBE_01892 7.3e-186 nss M transferase activity, transferring glycosyl groups
KDIFEGBE_01894 1.2e-114 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
KDIFEGBE_01899 1.4e-08 sraP UW domain, Protein
KDIFEGBE_01900 8.3e-25
KDIFEGBE_01901 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KDIFEGBE_01902 0.0 3.5.1.28 M domain protein
KDIFEGBE_01903 1.2e-137 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
KDIFEGBE_01904 5.1e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
KDIFEGBE_01905 6.9e-66 rmaI K Transcriptional regulator, MarR family
KDIFEGBE_01906 3.3e-237 EGP Major facilitator Superfamily
KDIFEGBE_01907 1.1e-122 XK27_00785 S CAAX protease self-immunity
KDIFEGBE_01909 3.9e-228 S dextransucrase activity
KDIFEGBE_01910 0.0 M Putative cell wall binding repeat
KDIFEGBE_01911 1.1e-281 S dextransucrase activity
KDIFEGBE_01912 1.5e-173 S dextransucrase activity
KDIFEGBE_01914 1.9e-07
KDIFEGBE_01919 4.4e-195 L Belongs to the 'phage' integrase family
KDIFEGBE_01920 3.5e-28 S Domain of unknown function (DUF3173)
KDIFEGBE_01921 1e-66
KDIFEGBE_01922 1.3e-229 L Replication initiation factor
KDIFEGBE_01923 1.4e-75
KDIFEGBE_01924 4e-75 K Transcriptional
KDIFEGBE_01925 3.8e-114 S CAAX protease self-immunity
KDIFEGBE_01926 1.2e-106 S Tetratricopeptide repeat
KDIFEGBE_01928 3.6e-159
KDIFEGBE_01930 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KDIFEGBE_01931 1.9e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KDIFEGBE_01932 1.2e-35 XK27_02060 S Transglycosylase associated protein
KDIFEGBE_01933 4.8e-70 badR K Transcriptional regulator, marr family
KDIFEGBE_01934 1.4e-93 S reductase
KDIFEGBE_01936 3.5e-288 ahpF O alkyl hydroperoxide reductase
KDIFEGBE_01937 4.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
KDIFEGBE_01938 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
KDIFEGBE_01939 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KDIFEGBE_01940 1.2e-82 S Putative small multi-drug export protein
KDIFEGBE_01941 2e-74 ctsR K Belongs to the CtsR family
KDIFEGBE_01942 0.0 clpC O Belongs to the ClpA ClpB family
KDIFEGBE_01943 1.9e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KDIFEGBE_01944 7.6e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KDIFEGBE_01945 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KDIFEGBE_01946 2.1e-140 S SseB protein N-terminal domain
KDIFEGBE_01947 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
KDIFEGBE_01948 1.5e-255 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KDIFEGBE_01949 1.4e-66 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KDIFEGBE_01951 1.8e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KDIFEGBE_01952 6e-91 yacP S RNA-binding protein containing a PIN domain
KDIFEGBE_01953 4.5e-152 degV S DegV family
KDIFEGBE_01955 5.1e-22 K Transcriptional
KDIFEGBE_01956 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KDIFEGBE_01957 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KDIFEGBE_01958 1.6e-32 int L DNA integration
KDIFEGBE_01959 9.3e-51 S membrane protein of uknown function UCP014873
KDIFEGBE_01960 1e-31 yegS 2.7.1.107 I lipid kinase activity
KDIFEGBE_01961 1.6e-105 L Transposase
KDIFEGBE_01962 9.8e-40
KDIFEGBE_01963 0.0 ctpC 3.6.3.10, 3.6.3.4 P p-ATPase superfamily P-type ATPase copper transporter
KDIFEGBE_01964 1.2e-101 cadD P cadmium resistance
KDIFEGBE_01965 4.5e-55 cadC K Bacterial regulatory protein, arsR family
KDIFEGBE_01966 7.6e-18
KDIFEGBE_01967 1.5e-29 K Helix-turn-helix domain
KDIFEGBE_01969 4.6e-149 srtB 3.4.22.70 S Sortase family
KDIFEGBE_01970 1.3e-232 capA M Bacterial capsule synthesis protein
KDIFEGBE_01971 6.1e-39 gcvR T UPF0237 protein
KDIFEGBE_01972 6.6e-243 XK27_08635 S UPF0210 protein
KDIFEGBE_01973 1.4e-130 ais G Phosphoglycerate mutase
KDIFEGBE_01974 5.3e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KDIFEGBE_01975 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
KDIFEGBE_01976 9.2e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KDIFEGBE_01977 6.3e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KDIFEGBE_01978 1.1e-301 dnaK O Heat shock 70 kDa protein
KDIFEGBE_01979 2.2e-103 thiJ-2 3.5.1.124 S DJ-1/PfpI family
KDIFEGBE_01980 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KDIFEGBE_01981 2e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KDIFEGBE_01982 3.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
KDIFEGBE_01983 1.5e-80 hmpT S cog cog4720
KDIFEGBE_01984 0.0 lpdA 1.8.1.4 C Dehydrogenase
KDIFEGBE_01985 2.1e-212 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KDIFEGBE_01986 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KDIFEGBE_01987 4.3e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KDIFEGBE_01988 1.8e-202 hpk9 2.7.13.3 T protein histidine kinase activity
KDIFEGBE_01989 7.3e-231 2.7.13.3 T protein histidine kinase activity
KDIFEGBE_01990 0.0 S the current gene model (or a revised gene model) may contain a frame shift
KDIFEGBE_01991 1.4e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KDIFEGBE_01992 4.5e-120 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KDIFEGBE_01993 3.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KDIFEGBE_01994 6.2e-249 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
KDIFEGBE_01995 1.6e-183 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
KDIFEGBE_01996 6.7e-156 rssA S Phospholipase, patatin family
KDIFEGBE_01997 1.4e-99 estA E Lysophospholipase L1 and related esterases
KDIFEGBE_01998 1.5e-286 S unusual protein kinase
KDIFEGBE_01999 4.9e-39 S granule-associated protein
KDIFEGBE_02000 9.8e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KDIFEGBE_02001 3e-196 S hmm pf01594
KDIFEGBE_02002 2.2e-105 G Belongs to the phosphoglycerate mutase family
KDIFEGBE_02003 2.8e-108 G Belongs to the phosphoglycerate mutase family
KDIFEGBE_02004 8.2e-108 pgm G Belongs to the phosphoglycerate mutase family
KDIFEGBE_02005 6.9e-150 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KDIFEGBE_02007 9.1e-187 wbbI M transferase activity, transferring glycosyl groups
KDIFEGBE_02008 2.3e-184 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
KDIFEGBE_02009 4.1e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
KDIFEGBE_02010 1.9e-157 S Acyltransferase family
KDIFEGBE_02011 7e-251 epsU S Polysaccharide biosynthesis protein
KDIFEGBE_02012 1.5e-174
KDIFEGBE_02013 1.1e-152 M Glycosyltransferase like family 2
KDIFEGBE_02014 6.5e-163 M Glycosyltransferase, group 2 family protein
KDIFEGBE_02015 7.1e-118 Z012_10770 M Domain of unknown function (DUF1919)
KDIFEGBE_02016 9.8e-211 wcoF M Glycosyltransferase, group 1 family protein
KDIFEGBE_02017 1.6e-221 rgpAc GT4 M group 1 family protein
KDIFEGBE_02018 1e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KDIFEGBE_02019 3.4e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
KDIFEGBE_02020 3.5e-110 cps4C M biosynthesis protein
KDIFEGBE_02021 3.4e-132 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
KDIFEGBE_02022 6.3e-247 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
KDIFEGBE_02023 2.6e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
KDIFEGBE_02024 1.8e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
KDIFEGBE_02025 1.8e-173 clcA_2 P Chloride transporter, ClC family
KDIFEGBE_02026 9.8e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KDIFEGBE_02027 2.7e-86 S Protein of unknown function (DUF1697)
KDIFEGBE_02028 2.3e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KDIFEGBE_02029 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KDIFEGBE_02030 2.5e-253 V Glucan-binding protein C
KDIFEGBE_02031 5.5e-226 V Glucan-binding protein C

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)