ORF_ID e_value Gene_name EC_number CAZy COGs Description
IKFEDCGB_00007 2.6e-161 ppaC 3.6.1.1 C inorganic pyrophosphatase
IKFEDCGB_00008 1.7e-100 S Domain of unknown function (DUF1803)
IKFEDCGB_00009 7.8e-102 ygaC J Belongs to the UPF0374 family
IKFEDCGB_00010 1.7e-134 recX 2.4.1.337 GT4 S Regulatory protein RecX
IKFEDCGB_00011 2.9e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IKFEDCGB_00012 8.8e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
IKFEDCGB_00013 3.1e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
IKFEDCGB_00014 8.1e-114 S HAD hydrolase, family IA, variant 3
IKFEDCGB_00015 3.1e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
IKFEDCGB_00016 5.2e-72 marR K Transcriptional regulator, MarR family
IKFEDCGB_00017 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IKFEDCGB_00018 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IKFEDCGB_00019 9.9e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
IKFEDCGB_00020 3.3e-161 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IKFEDCGB_00021 1.1e-125 IQ reductase
IKFEDCGB_00022 1.3e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IKFEDCGB_00023 1.6e-53 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IKFEDCGB_00024 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IKFEDCGB_00025 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IKFEDCGB_00026 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IKFEDCGB_00027 2.6e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IKFEDCGB_00028 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IKFEDCGB_00029 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
IKFEDCGB_00030 1.4e-112 fruR K transcriptional
IKFEDCGB_00031 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IKFEDCGB_00032 0.0 fruA 2.7.1.202 G phosphotransferase system
IKFEDCGB_00033 7.6e-255 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IKFEDCGB_00034 1.3e-229 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IKFEDCGB_00036 1.7e-210 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
IKFEDCGB_00037 1.8e-223 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IKFEDCGB_00038 1.8e-289 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IKFEDCGB_00039 4.1e-253 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IKFEDCGB_00040 6e-86 2.3.1.128 K acetyltransferase
IKFEDCGB_00041 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IKFEDCGB_00042 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IKFEDCGB_00043 3.9e-130 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IKFEDCGB_00044 5e-63 WQ51_03320 S cog cog4835
IKFEDCGB_00045 2.8e-146 XK27_08360 S EDD domain protein, DegV family
IKFEDCGB_00046 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IKFEDCGB_00047 8.4e-221 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IKFEDCGB_00048 0.0 yfmR S abc transporter atp-binding protein
IKFEDCGB_00049 3.8e-26 U response to pH
IKFEDCGB_00050 3.7e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
IKFEDCGB_00051 3.6e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
IKFEDCGB_00052 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IKFEDCGB_00053 2.1e-267 S Psort location CytoplasmicMembrane, score
IKFEDCGB_00054 1.8e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IKFEDCGB_00055 4.8e-73 K DNA-binding transcription factor activity
IKFEDCGB_00056 2.3e-310 lmrA1 V abc transporter atp-binding protein
IKFEDCGB_00057 0.0 lmrA2 V abc transporter atp-binding protein
IKFEDCGB_00058 7.4e-112 K Acetyltransferase (GNAT) family
IKFEDCGB_00059 3.3e-112 2.7.6.5 S Region found in RelA / SpoT proteins
IKFEDCGB_00060 8.3e-117 T response regulator
IKFEDCGB_00061 1.2e-214 sptS 2.7.13.3 T Histidine kinase
IKFEDCGB_00062 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IKFEDCGB_00063 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IKFEDCGB_00064 4.5e-160 cvfB S Protein conserved in bacteria
IKFEDCGB_00065 3.7e-34 yozE S Belongs to the UPF0346 family
IKFEDCGB_00066 1.3e-123 sip M LysM domain protein
IKFEDCGB_00067 5.2e-190 phoH T phosphate starvation-inducible protein PhoH
IKFEDCGB_00071 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IKFEDCGB_00072 4.4e-160 S reductase
IKFEDCGB_00073 4.7e-168 K transcriptional regulator (lysR family)
IKFEDCGB_00074 5.5e-106 S CAAX amino terminal protease family protein
IKFEDCGB_00075 3.2e-262 S Glucan-binding protein C
IKFEDCGB_00076 7e-170 coiA 3.6.4.12 S Competence protein
IKFEDCGB_00077 0.0 pepF E oligoendopeptidase F
IKFEDCGB_00078 4.5e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
IKFEDCGB_00079 6.7e-119 yrrM 2.1.1.104 S O-Methyltransferase
IKFEDCGB_00080 5.1e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
IKFEDCGB_00081 3e-84 yxjI S LURP-one-related
IKFEDCGB_00082 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IKFEDCGB_00083 6.1e-163 K sequence-specific DNA binding
IKFEDCGB_00084 5.9e-09
IKFEDCGB_00086 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IKFEDCGB_00087 1.8e-133 agrA KT phosphorelay signal transduction system
IKFEDCGB_00088 1.2e-228 2.7.13.3 T GHKL domain
IKFEDCGB_00089 7e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IKFEDCGB_00090 0.0 ftsI 3.4.16.4 M penicillin-binding protein
IKFEDCGB_00091 8.1e-46 ftsL D cell division protein FtsL
IKFEDCGB_00092 6.7e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IKFEDCGB_00093 1.4e-94
IKFEDCGB_00095 6.3e-48 yhaI J Protein of unknown function (DUF805)
IKFEDCGB_00096 1.3e-61 yhaI J Protein of unknown function (DUF805)
IKFEDCGB_00097 1e-32 yhaI J Protein of unknown function (DUF805)
IKFEDCGB_00098 1.6e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IKFEDCGB_00099 2.2e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IKFEDCGB_00100 1.1e-284 XK27_00765
IKFEDCGB_00101 8.9e-133 ecsA_2 V abc transporter atp-binding protein
IKFEDCGB_00102 1.5e-124 S Protein of unknown function (DUF554)
IKFEDCGB_00103 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IKFEDCGB_00104 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IKFEDCGB_00105 9.2e-240 2.7.13.3 T protein histidine kinase activity
IKFEDCGB_00106 9.4e-234 dcuS 2.7.13.3 T protein histidine kinase activity
IKFEDCGB_00107 6.8e-14
IKFEDCGB_00110 1.7e-145 V Psort location CytoplasmicMembrane, score
IKFEDCGB_00112 1.7e-298 O MreB/Mbl protein
IKFEDCGB_00113 2.6e-194 mccF V LD-carboxypeptidase
IKFEDCGB_00114 5.3e-119 liaI S membrane
IKFEDCGB_00115 1.5e-74 XK27_02470 K LytTr DNA-binding domain
IKFEDCGB_00116 3.4e-308 KT response to antibiotic
IKFEDCGB_00117 7.4e-113 yebC M Membrane
IKFEDCGB_00118 1.2e-258 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
IKFEDCGB_00119 3e-170 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IKFEDCGB_00121 2.9e-31 yozG K Transcriptional regulator
IKFEDCGB_00125 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IKFEDCGB_00126 5.7e-192 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IKFEDCGB_00127 5.8e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IKFEDCGB_00128 2.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IKFEDCGB_00129 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IKFEDCGB_00130 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IKFEDCGB_00132 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
IKFEDCGB_00133 3.8e-170 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
IKFEDCGB_00134 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
IKFEDCGB_00135 7.8e-290 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
IKFEDCGB_00136 9.2e-178 scrR K Transcriptional regulator
IKFEDCGB_00137 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IKFEDCGB_00138 1.7e-61 yqhY S protein conserved in bacteria
IKFEDCGB_00139 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IKFEDCGB_00140 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
IKFEDCGB_00141 7e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
IKFEDCGB_00142 2.8e-32 blpT
IKFEDCGB_00146 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IKFEDCGB_00147 1e-168 corA P COG0598 Mg2 and Co2 transporters
IKFEDCGB_00148 1e-122 XK27_01040 S Protein of unknown function (DUF1129)
IKFEDCGB_00150 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IKFEDCGB_00151 1.3e-80 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IKFEDCGB_00152 3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
IKFEDCGB_00153 8.5e-15 XK27_05745
IKFEDCGB_00154 4.4e-219 mutY L A G-specific adenine glycosylase
IKFEDCGB_00156 3.8e-34
IKFEDCGB_00158 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IKFEDCGB_00159 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IKFEDCGB_00160 6.1e-94 cvpA S toxin biosynthetic process
IKFEDCGB_00161 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IKFEDCGB_00162 2.2e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IKFEDCGB_00163 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IKFEDCGB_00164 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IKFEDCGB_00165 1.3e-46 azlD S branched-chain amino acid
IKFEDCGB_00166 9.7e-113 azlC E AzlC protein
IKFEDCGB_00167 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IKFEDCGB_00168 5.9e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IKFEDCGB_00169 1.2e-118 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
IKFEDCGB_00170 1.5e-33 ykzG S Belongs to the UPF0356 family
IKFEDCGB_00171 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IKFEDCGB_00172 3.2e-195 ylbM S Belongs to the UPF0348 family
IKFEDCGB_00173 1.9e-138 yqeM Q Methyltransferase domain protein
IKFEDCGB_00174 7.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IKFEDCGB_00175 3e-87 entB 3.5.1.19 Q Isochorismatase family
IKFEDCGB_00176 8.3e-105 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IKFEDCGB_00177 5.9e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IKFEDCGB_00178 7.7e-49 yhbY J RNA-binding protein
IKFEDCGB_00179 7.8e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IKFEDCGB_00180 5.1e-98 yqeG S hydrolase of the HAD superfamily
IKFEDCGB_00181 9.8e-145 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IKFEDCGB_00182 3.9e-190 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
IKFEDCGB_00183 2.8e-61
IKFEDCGB_00184 3.5e-215 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IKFEDCGB_00185 1.5e-57
IKFEDCGB_00186 2.2e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
IKFEDCGB_00187 5.7e-275 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
IKFEDCGB_00188 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
IKFEDCGB_00189 2.7e-30 S PQ loop repeat
IKFEDCGB_00190 3e-281 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IKFEDCGB_00192 1.1e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IKFEDCGB_00193 6.5e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IKFEDCGB_00194 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IKFEDCGB_00195 2.8e-42 tagE 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
IKFEDCGB_00196 5.4e-291 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IKFEDCGB_00197 6.4e-99 pncA Q isochorismatase
IKFEDCGB_00198 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IKFEDCGB_00199 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
IKFEDCGB_00200 1.2e-74 XK27_03180 T universal stress protein
IKFEDCGB_00202 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IKFEDCGB_00203 2.4e-10 MU outer membrane autotransporter barrel domain protein
IKFEDCGB_00204 3.8e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
IKFEDCGB_00205 5.6e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
IKFEDCGB_00206 0.0 yjcE P NhaP-type Na H and K H antiporters
IKFEDCGB_00208 5.5e-95 ytqB 2.1.1.176 J (SAM)-dependent
IKFEDCGB_00209 2.3e-181 yhcC S radical SAM protein
IKFEDCGB_00210 7.1e-187 ylbL T Belongs to the peptidase S16 family
IKFEDCGB_00211 1.1e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IKFEDCGB_00212 2.5e-92 rsmD 2.1.1.171 L Methyltransferase
IKFEDCGB_00213 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IKFEDCGB_00214 5e-10 S Protein of unknown function (DUF4059)
IKFEDCGB_00215 6.1e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
IKFEDCGB_00216 1.4e-162 yxeN P ABC transporter (Permease
IKFEDCGB_00217 9.7e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IKFEDCGB_00218 8e-35
IKFEDCGB_00219 1.2e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IKFEDCGB_00220 0.0 pflB 2.3.1.54 C formate acetyltransferase'
IKFEDCGB_00221 1.9e-141 cah 4.2.1.1 P carbonic anhydrase
IKFEDCGB_00222 1e-70 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKFEDCGB_00224 5.3e-170 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
IKFEDCGB_00225 4.7e-137 cppA E CppA N-terminal
IKFEDCGB_00226 2e-94 V CAAX protease self-immunity
IKFEDCGB_00227 5.6e-150 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
IKFEDCGB_00228 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IKFEDCGB_00229 1.8e-44 spiA K sequence-specific DNA binding
IKFEDCGB_00236 0.0 mdlB V abc transporter atp-binding protein
IKFEDCGB_00237 0.0 mdlA V abc transporter atp-binding protein
IKFEDCGB_00239 2.6e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
IKFEDCGB_00240 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IKFEDCGB_00241 1.8e-61 yutD J protein conserved in bacteria
IKFEDCGB_00242 1.1e-256 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IKFEDCGB_00245 2.9e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IKFEDCGB_00246 1.9e-289 amiA E ABC transporter, substrate-binding protein, family 5
IKFEDCGB_00247 2.8e-271 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IKFEDCGB_00248 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
IKFEDCGB_00249 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
IKFEDCGB_00250 2.4e-210 hpk9 2.7.13.3 T protein histidine kinase activity
IKFEDCGB_00251 2.3e-224 fasC 2.7.13.3 T protein histidine kinase activity
IKFEDCGB_00252 7.2e-130 fasA KT Response regulator of the LytR AlgR family
IKFEDCGB_00253 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IKFEDCGB_00254 7.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
IKFEDCGB_00255 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IKFEDCGB_00256 1.4e-145 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IKFEDCGB_00257 1.1e-168 jag S RNA-binding protein
IKFEDCGB_00258 2.4e-99 K Transcriptional regulator
IKFEDCGB_00259 1.2e-97 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
IKFEDCGB_00260 3.4e-14 rpmH J Ribosomal protein L34
IKFEDCGB_00261 2.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IKFEDCGB_00262 2.4e-49 L COG1943 Transposase and inactivated derivatives
IKFEDCGB_00263 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IKFEDCGB_00264 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IKFEDCGB_00265 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IKFEDCGB_00266 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IKFEDCGB_00267 1.5e-67 S cog cog4699
IKFEDCGB_00268 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IKFEDCGB_00269 2.4e-159 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IKFEDCGB_00270 2.2e-43 comGC U Required for transformation and DNA binding
IKFEDCGB_00271 1.4e-69 cglD NU Competence protein
IKFEDCGB_00272 5.3e-15 NU Type II secretory pathway pseudopilin
IKFEDCGB_00273 5.4e-69 comGF U Competence protein ComGF
IKFEDCGB_00274 2e-12 comGF U Putative Competence protein ComGF
IKFEDCGB_00275 5e-176 ytxK 2.1.1.72 L DNA methylase
IKFEDCGB_00276 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IKFEDCGB_00277 8.8e-27 lanR K sequence-specific DNA binding
IKFEDCGB_00278 2.5e-110 V CAAX protease self-immunity
IKFEDCGB_00280 1.4e-100 S CAAX amino terminal protease family protein
IKFEDCGB_00281 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IKFEDCGB_00282 3.5e-202 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IKFEDCGB_00283 2.7e-08 XK27_10305 S Domain of unknown function (DUF4651)
IKFEDCGB_00284 4.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IKFEDCGB_00286 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IKFEDCGB_00287 3.7e-117 S CAAX protease self-immunity
IKFEDCGB_00288 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IKFEDCGB_00289 6.6e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IKFEDCGB_00293 2e-157 rrmA 2.1.1.187 Q methyltransferase
IKFEDCGB_00294 5.6e-138 S HAD hydrolase, family IA, variant
IKFEDCGB_00295 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IKFEDCGB_00296 6.7e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IKFEDCGB_00297 1.6e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IKFEDCGB_00298 7.5e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
IKFEDCGB_00299 1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IKFEDCGB_00300 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IKFEDCGB_00301 7.9e-97 XK27_08585 S Psort location CytoplasmicMembrane, score
IKFEDCGB_00302 1.4e-139 fnt P Formate nitrite transporter
IKFEDCGB_00303 7.9e-230 XK27_09615 C reductase
IKFEDCGB_00304 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
IKFEDCGB_00305 8e-76 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IKFEDCGB_00306 6.6e-73 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
IKFEDCGB_00307 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IKFEDCGB_00308 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
IKFEDCGB_00309 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
IKFEDCGB_00310 1.2e-50 S Protein of unknown function (DUF3397)
IKFEDCGB_00311 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IKFEDCGB_00312 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IKFEDCGB_00313 1.5e-207 trsE S COG0433 Predicted ATPase
IKFEDCGB_00314 4.3e-07
IKFEDCGB_00315 2e-162 3.4.17.14 NU amidase activity
IKFEDCGB_00316 1.7e-25
IKFEDCGB_00318 5.7e-32
IKFEDCGB_00319 1.7e-202 repE K Primase C terminal 1 (PriCT-1)
IKFEDCGB_00321 2.9e-21
IKFEDCGB_00322 9.1e-16 S Thioredoxin
IKFEDCGB_00323 1.3e-72
IKFEDCGB_00325 1.6e-18 S the current gene model (or a revised gene model) may contain a frame shift
IKFEDCGB_00326 3.5e-34 S the current gene model (or a revised gene model) may contain a frame shift
IKFEDCGB_00327 2.7e-103 ada 3.2.2.21 F DNA/RNA non-specific endonuclease
IKFEDCGB_00328 1.6e-18
IKFEDCGB_00329 2.6e-210 ruvB 3.6.4.12 L four-way junction helicase activity
IKFEDCGB_00332 2.7e-41 yhaM L Shows a 3'-5' exoribonuclease activity
IKFEDCGB_00333 3.5e-07
IKFEDCGB_00334 0.0 EL Toprim-like
IKFEDCGB_00337 5e-190 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IKFEDCGB_00338 2.6e-245 clpB O Belongs to the ClpA ClpB family
IKFEDCGB_00339 1.7e-17
IKFEDCGB_00340 2.6e-96
IKFEDCGB_00342 8.4e-15 M LPXTG cell wall anchor motif
IKFEDCGB_00344 0.0 U COG3505 Type IV secretory pathway, VirD4 components
IKFEDCGB_00345 3.9e-62 tnpR L Resolvase, N terminal domain
IKFEDCGB_00346 2.7e-122 D CobQ CobB MinD ParA nucleotide binding domain protein
IKFEDCGB_00349 6.2e-10
IKFEDCGB_00350 7.3e-209 I mechanosensitive ion channel activity
IKFEDCGB_00351 3.2e-22 S BRCA1 C Terminus (BRCT) domain
IKFEDCGB_00354 4.9e-16 S Uncharacterized protein pXO2-11
IKFEDCGB_00355 8.4e-41
IKFEDCGB_00360 2.6e-10
IKFEDCGB_00363 1.9e-07
IKFEDCGB_00368 4.2e-198 L Belongs to the 'phage' integrase family
IKFEDCGB_00369 3.5e-28 S Domain of unknown function (DUF3173)
IKFEDCGB_00370 3.4e-67
IKFEDCGB_00371 1e-226 L Replication initiation factor
IKFEDCGB_00372 7.2e-75
IKFEDCGB_00373 1e-75 K Transcriptional
IKFEDCGB_00374 3.6e-49 qacC P COG2076 Membrane transporters of cations and cationic drugs
IKFEDCGB_00375 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IKFEDCGB_00376 6.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IKFEDCGB_00377 5.5e-36 XK27_02060 S Transglycosylase associated protein
IKFEDCGB_00378 8.3e-38 badR K Transcriptional regulator, marr family
IKFEDCGB_00379 3.2e-95 S reductase
IKFEDCGB_00381 1.5e-286 ahpF O alkyl hydroperoxide reductase
IKFEDCGB_00382 3.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
IKFEDCGB_00383 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
IKFEDCGB_00384 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IKFEDCGB_00385 1.6e-82 S Putative small multi-drug export protein
IKFEDCGB_00386 1.8e-75 ctsR K Belongs to the CtsR family
IKFEDCGB_00387 0.0 clpC O Belongs to the ClpA ClpB family
IKFEDCGB_00388 2.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IKFEDCGB_00389 2.6e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IKFEDCGB_00390 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IKFEDCGB_00391 2.7e-140 S SseB protein N-terminal domain
IKFEDCGB_00392 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
IKFEDCGB_00393 3.1e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IKFEDCGB_00394 3.6e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IKFEDCGB_00396 3.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IKFEDCGB_00397 6e-91 yacP S RNA-binding protein containing a PIN domain
IKFEDCGB_00398 4.5e-152 degV S DegV family
IKFEDCGB_00400 5.1e-22 K Transcriptional
IKFEDCGB_00401 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IKFEDCGB_00402 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
IKFEDCGB_00403 3e-31 int L DNA integration
IKFEDCGB_00404 3.8e-52 S membrane protein of uknown function UCP014873
IKFEDCGB_00405 6.4e-60 L MULE transposase domain
IKFEDCGB_00406 2.6e-40
IKFEDCGB_00407 0.0 ctpC 3.6.3.10, 3.6.3.4 P p-ATPase superfamily P-type ATPase copper transporter
IKFEDCGB_00409 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IKFEDCGB_00411 5.4e-69 K LytTr DNA-binding domain
IKFEDCGB_00412 1.3e-78 S Protein of unknown function (DUF3021)
IKFEDCGB_00413 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IKFEDCGB_00414 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IKFEDCGB_00415 3.1e-69 argR K Regulates arginine biosynthesis genes
IKFEDCGB_00416 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IKFEDCGB_00417 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IKFEDCGB_00418 6.2e-93
IKFEDCGB_00419 2.4e-107 comF 2.4.2.14 K competence protein
IKFEDCGB_00420 1.9e-30
IKFEDCGB_00421 2.4e-217
IKFEDCGB_00422 9.7e-200 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IKFEDCGB_00423 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IKFEDCGB_00424 7.9e-238 purD 6.3.4.13 F Belongs to the GARS family
IKFEDCGB_00425 1.6e-20 D Plasmid stabilization system
IKFEDCGB_00426 4.3e-14 XK27_10545
IKFEDCGB_00427 3.9e-156 S CHAP domain
IKFEDCGB_00428 5.6e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IKFEDCGB_00429 1.1e-98 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IKFEDCGB_00430 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IKFEDCGB_00431 7.8e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IKFEDCGB_00432 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IKFEDCGB_00433 3.4e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IKFEDCGB_00434 4.8e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IKFEDCGB_00435 3.5e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IKFEDCGB_00436 1.3e-137 recO L Involved in DNA repair and RecF pathway recombination
IKFEDCGB_00437 6.7e-215 araT 2.6.1.1 E Aminotransferase
IKFEDCGB_00438 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IKFEDCGB_00439 2.3e-82 usp 3.5.1.28 CBM50 S CHAP domain
IKFEDCGB_00440 3.9e-82 mreD M rod shape-determining protein MreD
IKFEDCGB_00441 4.9e-111 mreC M Involved in formation and maintenance of cell shape
IKFEDCGB_00447 2.6e-10
IKFEDCGB_00455 1.9e-67 M Pfam:DUF1792
IKFEDCGB_00456 1.7e-85 M Pfam:DUF1792
IKFEDCGB_00457 9.1e-108 M Pfam:DUF1792
IKFEDCGB_00458 1.2e-185 nss M transferase activity, transferring glycosyl groups
IKFEDCGB_00459 3.6e-16 S Accessory secretory protein Sec, Asp5
IKFEDCGB_00460 2.6e-17 S Accessory secretory protein Sec Asp4
IKFEDCGB_00461 5.7e-242 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IKFEDCGB_00462 2e-280 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IKFEDCGB_00463 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IKFEDCGB_00464 5e-78 asp3 S Accessory Sec system protein Asp3
IKFEDCGB_00465 6.4e-290 asp2 3.4.11.5 S Accessory Sec system protein Asp2
IKFEDCGB_00466 2.3e-287 asp1 S Accessory Sec system protein Asp1
IKFEDCGB_00467 9.5e-212 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
IKFEDCGB_00468 0.0 M family 8
IKFEDCGB_00470 0.0 sbcC L ATPase involved in DNA repair
IKFEDCGB_00471 6e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IKFEDCGB_00472 0.0 GM domain, Protein
IKFEDCGB_00473 0.0 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
IKFEDCGB_00474 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKFEDCGB_00475 3.2e-220 vicK 2.7.13.3 T Histidine kinase
IKFEDCGB_00476 2.3e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
IKFEDCGB_00477 4.3e-56 S Protein of unknown function (DUF454)
IKFEDCGB_00478 2.3e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
IKFEDCGB_00479 5e-145 yidA S hydrolases of the HAD superfamily
IKFEDCGB_00480 1.3e-135 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
IKFEDCGB_00481 5.1e-131 XK27_00120 2.4.2.3 F Phosphorylase superfamily
IKFEDCGB_00482 1.7e-66 ywiB S Domain of unknown function (DUF1934)
IKFEDCGB_00483 0.0 pacL 3.6.3.8 P cation transport ATPase
IKFEDCGB_00484 6.1e-129 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IKFEDCGB_00485 9.5e-155 yjjH S Calcineurin-like phosphoesterase
IKFEDCGB_00486 4.2e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IKFEDCGB_00487 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IKFEDCGB_00488 5.5e-124 ftsE D cell division ATP-binding protein FtsE
IKFEDCGB_00489 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IKFEDCGB_00490 3.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
IKFEDCGB_00491 4.3e-177 yubA S permease
IKFEDCGB_00492 1.7e-224 G COG0457 FOG TPR repeat
IKFEDCGB_00493 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IKFEDCGB_00494 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IKFEDCGB_00495 3.3e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IKFEDCGB_00496 6.6e-87 ebsA S Family of unknown function (DUF5322)
IKFEDCGB_00497 2.5e-17 M LysM domain
IKFEDCGB_00498 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IKFEDCGB_00499 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IKFEDCGB_00500 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IKFEDCGB_00501 2.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IKFEDCGB_00502 1.1e-83 XK27_03610 K Gnat family
IKFEDCGB_00503 3.9e-90 yybC
IKFEDCGB_00504 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IKFEDCGB_00505 1.8e-270 pepV 3.5.1.18 E Dipeptidase
IKFEDCGB_00506 2.1e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
IKFEDCGB_00507 0.0 M domain protein
IKFEDCGB_00508 0.0 M domain protein
IKFEDCGB_00509 6.8e-179 bipA Q Transposase
IKFEDCGB_00510 7.7e-155 endA F DNA RNA non-specific endonuclease
IKFEDCGB_00511 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
IKFEDCGB_00512 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IKFEDCGB_00513 4.8e-11 S Protein of unknown function (DUF1146)
IKFEDCGB_00514 2.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IKFEDCGB_00515 1.4e-134 G Domain of unknown function (DUF4832)
IKFEDCGB_00516 9.2e-84 S membrane
IKFEDCGB_00517 5.1e-96 P VTC domain
IKFEDCGB_00518 1.5e-221 cotH M CotH kinase protein
IKFEDCGB_00519 2.6e-184 pelG M Putative exopolysaccharide Exporter (EPS-E)
IKFEDCGB_00520 1.1e-272 pelF GT4 M Domain of unknown function (DUF3492)
IKFEDCGB_00521 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
IKFEDCGB_00522 1.5e-145
IKFEDCGB_00523 1.8e-275 5.1.3.2 GM Psort location CytoplasmicMembrane, score
IKFEDCGB_00524 3.5e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IKFEDCGB_00525 7.3e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IKFEDCGB_00526 5.4e-303 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IKFEDCGB_00527 3.3e-86 ytsP 1.8.4.14 T GAF domain-containing protein
IKFEDCGB_00528 1.6e-163 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IKFEDCGB_00529 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
IKFEDCGB_00532 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IKFEDCGB_00533 2.8e-211 XK27_05110 P Chloride transporter ClC family
IKFEDCGB_00534 1.8e-38 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
IKFEDCGB_00535 2.1e-280 clcA P Chloride transporter, ClC family
IKFEDCGB_00536 1e-75 fld C Flavodoxin
IKFEDCGB_00537 2.8e-18 XK27_08880
IKFEDCGB_00538 5.5e-127 XK27_08875 O Zinc-dependent metalloprotease
IKFEDCGB_00539 9.5e-149 estA CE1 S Esterase
IKFEDCGB_00540 7.8e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IKFEDCGB_00541 7.6e-135 XK27_08845 S abc transporter atp-binding protein
IKFEDCGB_00542 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
IKFEDCGB_00543 1.1e-176 XK27_08835 S ABC transporter substrate binding protein
IKFEDCGB_00544 1.7e-18 S Domain of unknown function (DUF4649)
IKFEDCGB_00545 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
IKFEDCGB_00546 1e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IKFEDCGB_00547 2.6e-186 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IKFEDCGB_00548 0.0 dnaE 2.7.7.7 L DNA polymerase
IKFEDCGB_00549 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IKFEDCGB_00550 1.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IKFEDCGB_00551 5.5e-16 ysdA L Membrane
IKFEDCGB_00552 1.1e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IKFEDCGB_00553 4.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IKFEDCGB_00554 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IKFEDCGB_00555 1.4e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
IKFEDCGB_00557 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IKFEDCGB_00558 1.8e-96 ypmS S Protein conserved in bacteria
IKFEDCGB_00559 1.5e-155 ypmR E COG2755 Lysophospholipase L1 and related esterases
IKFEDCGB_00560 7.1e-142 DegV S DegV family
IKFEDCGB_00561 8.7e-301 recN L May be involved in recombinational repair of damaged DNA
IKFEDCGB_00562 2.8e-73 argR K Regulates arginine biosynthesis genes
IKFEDCGB_00563 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IKFEDCGB_00564 1.8e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IKFEDCGB_00565 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IKFEDCGB_00566 6.2e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IKFEDCGB_00568 3.8e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IKFEDCGB_00569 2.1e-123 dnaD
IKFEDCGB_00570 3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IKFEDCGB_00571 4.9e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IKFEDCGB_00572 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
IKFEDCGB_00573 2.9e-64 GnaT 2.5.1.16 K acetyltransferase
IKFEDCGB_00574 2.1e-32 Q Methyltransferase domain
IKFEDCGB_00575 6.2e-80 Q Methyltransferase domain
IKFEDCGB_00576 2e-135 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IKFEDCGB_00577 5.9e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IKFEDCGB_00578 2.9e-111 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IKFEDCGB_00579 5.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IKFEDCGB_00580 4.9e-236 rodA D Belongs to the SEDS family
IKFEDCGB_00581 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
IKFEDCGB_00582 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
IKFEDCGB_00583 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
IKFEDCGB_00584 6.7e-179 XK27_08075 M glycosyl transferase family 2
IKFEDCGB_00585 2.8e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
IKFEDCGB_00586 3.5e-143 P molecular chaperone
IKFEDCGB_00587 6.9e-95 XK27_05505 S Psort location CytoplasmicMembrane, score
IKFEDCGB_00591 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
IKFEDCGB_00592 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IKFEDCGB_00593 1.8e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IKFEDCGB_00594 2.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IKFEDCGB_00595 2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IKFEDCGB_00596 2.6e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IKFEDCGB_00597 4.6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IKFEDCGB_00598 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IKFEDCGB_00599 4.5e-180 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IKFEDCGB_00600 9.3e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IKFEDCGB_00601 3.7e-61 XK27_08085
IKFEDCGB_00602 1.2e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IKFEDCGB_00603 3.7e-134 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
IKFEDCGB_00604 4.3e-115 ylfI S tigr01906
IKFEDCGB_00605 1.2e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IKFEDCGB_00606 6.9e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
IKFEDCGB_00607 2.5e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
IKFEDCGB_00608 3.7e-30 KT response to antibiotic
IKFEDCGB_00610 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IKFEDCGB_00611 3.5e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IKFEDCGB_00612 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IKFEDCGB_00613 1.1e-258 S phospholipase Carboxylesterase
IKFEDCGB_00614 7.9e-202 yurR 1.4.5.1 E oxidoreductase
IKFEDCGB_00615 3.3e-144 zupT P Mediates zinc uptake. May also transport other divalent cations
IKFEDCGB_00616 1.7e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IKFEDCGB_00617 3.4e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
IKFEDCGB_00618 1.3e-64 gtrA S GtrA-like protein
IKFEDCGB_00619 3.7e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IKFEDCGB_00620 1.1e-162 ybbR S Protein conserved in bacteria
IKFEDCGB_00621 7.9e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IKFEDCGB_00622 1e-251 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
IKFEDCGB_00623 8.1e-148 cobQ S glutamine amidotransferase
IKFEDCGB_00624 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IKFEDCGB_00625 4.4e-132 pip 1.11.1.10 S Alpha beta hydrolase
IKFEDCGB_00626 7.5e-62 CP_0600 3.5.4.2, 3.5.4.4 F Adenosine/AMP deaminase
IKFEDCGB_00628 2.7e-39 MA20_06245 S yiaA/B two helix domain
IKFEDCGB_00629 0.0 uup S abc transporter atp-binding protein
IKFEDCGB_00630 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
IKFEDCGB_00631 3.9e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
IKFEDCGB_00632 4.6e-224 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
IKFEDCGB_00633 2.7e-153 XK27_05675 S Esterase
IKFEDCGB_00634 3.9e-161 XK27_05670 S Putative esterase
IKFEDCGB_00635 1.5e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
IKFEDCGB_00636 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IKFEDCGB_00637 3e-38 ptsH G phosphocarrier protein Hpr
IKFEDCGB_00638 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
IKFEDCGB_00639 1.3e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
IKFEDCGB_00640 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IKFEDCGB_00641 6.5e-34 nrdH O Glutaredoxin
IKFEDCGB_00642 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IKFEDCGB_00643 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IKFEDCGB_00644 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IKFEDCGB_00645 5.5e-137 divIVA D Cell division initiation protein
IKFEDCGB_00646 2.3e-137 ylmH S conserved protein, contains S4-like domain
IKFEDCGB_00647 1.7e-30 yggT D integral membrane protein
IKFEDCGB_00648 2e-90 sepF D cell septum assembly
IKFEDCGB_00649 6.9e-119 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IKFEDCGB_00650 3.3e-234 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IKFEDCGB_00651 2.8e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IKFEDCGB_00652 1.7e-130 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IKFEDCGB_00653 2.3e-198 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IKFEDCGB_00654 6.1e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IKFEDCGB_00656 0.0 typA T GTP-binding protein TypA
IKFEDCGB_00657 5.4e-178 glk 2.7.1.2 G Glucokinase
IKFEDCGB_00658 7.1e-27 yqgQ S protein conserved in bacteria
IKFEDCGB_00659 4.4e-79 perR P Belongs to the Fur family
IKFEDCGB_00660 4.9e-85 dps P Belongs to the Dps family
IKFEDCGB_00661 5.4e-105 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
IKFEDCGB_00662 1.5e-160 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
IKFEDCGB_00663 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
IKFEDCGB_00664 2.9e-185 holA 2.7.7.7 L DNA polymerase III delta subunit
IKFEDCGB_00665 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IKFEDCGB_00666 2.1e-64 S Domain of unknown function (DUF4430)
IKFEDCGB_00667 2.1e-74 S Psort location CytoplasmicMembrane, score
IKFEDCGB_00668 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
IKFEDCGB_00669 8.7e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
IKFEDCGB_00670 3.3e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
IKFEDCGB_00671 9.1e-113 sirR K iron dependent repressor
IKFEDCGB_00672 4e-135 htpX O Belongs to the peptidase M48B family
IKFEDCGB_00673 1.1e-90 lemA S LemA family
IKFEDCGB_00674 1.3e-171 spd F DNA RNA non-specific endonuclease
IKFEDCGB_00675 0.0 2.4.1.21 GT5 M Right handed beta helix region
IKFEDCGB_00676 2.1e-70 S double-stranded DNA endodeoxyribonuclease activity
IKFEDCGB_00677 1.1e-50 S PD-(D/E)XK nuclease family transposase
IKFEDCGB_00678 1.2e-188 L Uncharacterized conserved protein (DUF2075)
IKFEDCGB_00679 1e-43 S Nucleotide pyrophosphohydrolase
IKFEDCGB_00680 2.5e-133 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IKFEDCGB_00681 4.2e-193 MA20_36090 S Protein of unknown function (DUF2974)
IKFEDCGB_00682 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKFEDCGB_00683 8.6e-156 5.2.1.8 G hydrolase
IKFEDCGB_00684 3e-26 P Hemerythrin HHE cation binding domain protein
IKFEDCGB_00685 9.3e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
IKFEDCGB_00686 5.7e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IKFEDCGB_00687 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
IKFEDCGB_00689 1.2e-174 S hydrolase
IKFEDCGB_00690 8.4e-23
IKFEDCGB_00691 2.4e-136 M LysM domain
IKFEDCGB_00692 3.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IKFEDCGB_00693 3.8e-11
IKFEDCGB_00694 0.0 L helicase
IKFEDCGB_00695 1.2e-64 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
IKFEDCGB_00696 5.1e-13
IKFEDCGB_00697 1.3e-233 mntH P H( )-stimulated, divalent metal cation uptake system
IKFEDCGB_00698 1.1e-33 XK27_12190 S protein conserved in bacteria
IKFEDCGB_00700 1.1e-87 bioY S biotin synthase
IKFEDCGB_00701 7.5e-252 yegQ O Peptidase U32
IKFEDCGB_00702 1.5e-177 yegQ O Peptidase U32
IKFEDCGB_00704 3e-67 ytxH S General stress protein
IKFEDCGB_00705 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IKFEDCGB_00706 2.6e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IKFEDCGB_00707 8.3e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IKFEDCGB_00708 2.2e-41 pspC KT PspC domain
IKFEDCGB_00709 0.0 yhgF K Transcriptional accessory protein
IKFEDCGB_00711 1.9e-156 XK27_03015 S permease
IKFEDCGB_00712 8.4e-148 ycgQ S TIGR03943 family
IKFEDCGB_00713 1.8e-285 sulP P Sulfate permease and related transporters (MFS superfamily)
IKFEDCGB_00714 3.8e-100
IKFEDCGB_00715 3.5e-42 estA E GDSL-like Lipase/Acylhydrolase
IKFEDCGB_00716 2.7e-42 estA E GDSL-like Lipase/Acylhydrolase
IKFEDCGB_00717 3.7e-92 S CAAX protease self-immunity
IKFEDCGB_00718 8.8e-49
IKFEDCGB_00720 8.2e-63 yqeB S Pyrimidine dimer DNA glycosylase
IKFEDCGB_00721 3.7e-61 S Protein of unknown function (DUF1722)
IKFEDCGB_00722 1.3e-19 M Bacterial lipoprotein
IKFEDCGB_00723 7.5e-10
IKFEDCGB_00724 1.3e-126 V CAAX protease self-immunity
IKFEDCGB_00725 1.2e-46
IKFEDCGB_00726 1.7e-73 K TetR family transcriptional regulator
IKFEDCGB_00727 9.9e-82 Q Methyltransferase domain
IKFEDCGB_00728 1.2e-142 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IKFEDCGB_00729 1.3e-174 acoB C dehydrogenase E1 component
IKFEDCGB_00730 3.6e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
IKFEDCGB_00731 4.3e-173 pdhD 1.8.1.4 C Dehydrogenase
IKFEDCGB_00732 7.8e-10 S CsbD-like
IKFEDCGB_00733 8.6e-09 K CsbD-like
IKFEDCGB_00734 7.7e-68 S Asp23 family, cell envelope-related function
IKFEDCGB_00735 1.3e-21 S Small integral membrane protein
IKFEDCGB_00736 4.7e-97
IKFEDCGB_00737 3e-29 S Transglycosylase associated protein
IKFEDCGB_00739 4.7e-172 S Domain of unknown function (DUF389)
IKFEDCGB_00740 7.4e-158 yegS 2.7.1.107 I Diacylglycerol kinase
IKFEDCGB_00741 8.4e-125 ybbA S Putative esterase
IKFEDCGB_00742 3.2e-173 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IKFEDCGB_00743 3.7e-134 fecE 3.6.3.34 HP ABC transporter
IKFEDCGB_00744 3.6e-159 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKFEDCGB_00745 3.5e-124 V CAAX protease self-immunity
IKFEDCGB_00746 4.3e-147 S Domain of unknown function (DUF4300)
IKFEDCGB_00748 1.2e-112 cutC P Participates in the control of copper homeostasis
IKFEDCGB_00749 6.8e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
IKFEDCGB_00750 2.4e-153 yitS S EDD domain protein, DegV family
IKFEDCGB_00751 1.3e-202 yeaN P transporter
IKFEDCGB_00752 6.7e-136 S Domain of unknown function (DUF4336)
IKFEDCGB_00753 4.7e-132 S Alpha/beta hydrolase family
IKFEDCGB_00755 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IKFEDCGB_00756 1.6e-61 smtB K Transcriptional regulator
IKFEDCGB_00757 1.1e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
IKFEDCGB_00758 5.1e-78 P Mediates zinc uptake. May also transport other divalent cations
IKFEDCGB_00759 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IKFEDCGB_00760 5.9e-55
IKFEDCGB_00761 8.7e-60
IKFEDCGB_00762 1.1e-49
IKFEDCGB_00763 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
IKFEDCGB_00764 2e-217 EGP Transmembrane secretion effector
IKFEDCGB_00765 4.3e-22
IKFEDCGB_00766 3.2e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IKFEDCGB_00767 2e-97 mip S hydroperoxide reductase activity
IKFEDCGB_00768 5.5e-200 I acyl-CoA dehydrogenase
IKFEDCGB_00769 1.3e-149 ydiA P C4-dicarboxylate transporter malic acid transport
IKFEDCGB_00770 6.4e-244 msrR K Transcriptional regulator
IKFEDCGB_00771 3.9e-153 pheA 4.2.1.51 E Prephenate dehydratase
IKFEDCGB_00772 4.5e-80 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IKFEDCGB_00773 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IKFEDCGB_00774 3.3e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IKFEDCGB_00775 4.2e-53 yheA S Belongs to the UPF0342 family
IKFEDCGB_00776 1e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IKFEDCGB_00777 1.9e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IKFEDCGB_00778 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IKFEDCGB_00779 2.2e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IKFEDCGB_00780 7.5e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IKFEDCGB_00781 3.5e-216 ywbD 2.1.1.191 J Methyltransferase
IKFEDCGB_00782 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IKFEDCGB_00783 1.2e-25 WQ51_00785
IKFEDCGB_00784 8e-137 S peptidoglycan catabolic process
IKFEDCGB_00785 2.1e-22 S COG5546 Small integral membrane protein
IKFEDCGB_00786 4.4e-63 S Pfam:Phage_holin_4_1
IKFEDCGB_00787 5e-21
IKFEDCGB_00788 1.8e-166 S peptidoglycan catabolic process
IKFEDCGB_00789 6.4e-107
IKFEDCGB_00790 3.2e-252 S transmembrane transport
IKFEDCGB_00791 3.6e-87 S Bacteriophage Gp15 protein
IKFEDCGB_00792 2.6e-24
IKFEDCGB_00793 7.6e-76
IKFEDCGB_00794 4.3e-52 S Minor capsid protein from bacteriophage
IKFEDCGB_00795 3.1e-23 S Minor capsid protein
IKFEDCGB_00796 2.5e-26 S Minor capsid protein
IKFEDCGB_00797 1.7e-37
IKFEDCGB_00799 3.1e-140
IKFEDCGB_00800 1.4e-48 S Phage minor structural protein GP20
IKFEDCGB_00801 6.3e-125 M Phage minor capsid protein 2
IKFEDCGB_00802 2.2e-234 S Phage portal protein, SPP1 Gp6-like
IKFEDCGB_00803 5.7e-223 S Phage terminase large subunit
IKFEDCGB_00804 2.7e-40 L DNA packaging
IKFEDCGB_00806 2.9e-37
IKFEDCGB_00808 3.4e-27 S sequence-specific DNA binding
IKFEDCGB_00809 7.1e-20 S Protein of unknown function (DUF1642)
IKFEDCGB_00813 1.8e-55 rusA L crossover junction endodeoxyribonuclease RusA
IKFEDCGB_00814 4.5e-15
IKFEDCGB_00815 0.0 L Primase C terminal 2 (PriCT-2)
IKFEDCGB_00816 1.3e-266 L helicase
IKFEDCGB_00817 7.3e-69
IKFEDCGB_00818 6.3e-78
IKFEDCGB_00819 1.6e-49
IKFEDCGB_00820 2.6e-128 S AAA domain
IKFEDCGB_00821 9e-184 D AAA domain
IKFEDCGB_00822 1.5e-66 M Pilin isopeptide linkage domain protein
IKFEDCGB_00825 1.8e-24
IKFEDCGB_00828 4.7e-07 K sequence-specific DNA binding
IKFEDCGB_00829 1.2e-50 S protein disulfide oxidoreductase activity
IKFEDCGB_00830 3.5e-19 E Pfam:DUF955
IKFEDCGB_00831 9.7e-206 S Phage integrase family
IKFEDCGB_00832 8.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IKFEDCGB_00833 3.1e-75 yueI S Protein of unknown function (DUF1694)
IKFEDCGB_00834 1.4e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IKFEDCGB_00835 3.6e-199 yyaQ S YjbR
IKFEDCGB_00836 2.4e-181 ccpA K Catabolite control protein A
IKFEDCGB_00837 2.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
IKFEDCGB_00838 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
IKFEDCGB_00839 2.1e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IKFEDCGB_00840 1.9e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IKFEDCGB_00841 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IKFEDCGB_00842 2e-33 secG U Preprotein translocase subunit SecG
IKFEDCGB_00843 4.7e-219 mdtG EGP Major facilitator Superfamily
IKFEDCGB_00844 4.3e-101 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IKFEDCGB_00845 1.7e-148 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IKFEDCGB_00846 3.7e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IKFEDCGB_00847 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IKFEDCGB_00848 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IKFEDCGB_00849 6e-149 licT K antiterminator
IKFEDCGB_00850 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IKFEDCGB_00851 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
IKFEDCGB_00852 9.8e-144 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IKFEDCGB_00853 3.1e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IKFEDCGB_00854 2.6e-146 I Alpha/beta hydrolase family
IKFEDCGB_00855 8.6e-08
IKFEDCGB_00856 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IKFEDCGB_00857 1.6e-77 feoA P FeoA domain protein
IKFEDCGB_00858 3.2e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
IKFEDCGB_00859 1.7e-117 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
IKFEDCGB_00860 1e-34 ykuJ S protein conserved in bacteria
IKFEDCGB_00861 1.3e-179 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IKFEDCGB_00862 0.0 clpE O Belongs to the ClpA ClpB family
IKFEDCGB_00863 5.1e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IKFEDCGB_00864 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
IKFEDCGB_00865 1.7e-171 S oxidoreductase
IKFEDCGB_00866 3.9e-114 M Pfam SNARE associated Golgi protein
IKFEDCGB_00867 2.1e-106 S Domain of Unknown Function with PDB structure (DUF3862)
IKFEDCGB_00870 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
IKFEDCGB_00873 4.8e-16 S Protein of unknown function (DUF2969)
IKFEDCGB_00874 4.5e-199 ilvE 2.6.1.42 E Aminotransferase
IKFEDCGB_00875 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IKFEDCGB_00876 1.5e-09
IKFEDCGB_00878 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IKFEDCGB_00879 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IKFEDCGB_00880 6.1e-13 L Helix-hairpin-helix DNA-binding motif class 1
IKFEDCGB_00881 2.2e-30 S Domain of unknown function (DUF1912)
IKFEDCGB_00882 1.3e-171 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
IKFEDCGB_00883 8.3e-249 mmuP E amino acid
IKFEDCGB_00884 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
IKFEDCGB_00885 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IKFEDCGB_00886 9.7e-22
IKFEDCGB_00887 1.2e-88 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IKFEDCGB_00888 5.5e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IKFEDCGB_00889 1.7e-202 mvaS 2.3.3.10 I synthase
IKFEDCGB_00890 7.7e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IKFEDCGB_00891 1.1e-77 K hmm pf08876
IKFEDCGB_00892 5.2e-119 yqfA K protein, Hemolysin III
IKFEDCGB_00893 1.8e-195 S Protein of unknown function (DUF3114)
IKFEDCGB_00894 7.4e-156 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IKFEDCGB_00895 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IKFEDCGB_00896 8.8e-10
IKFEDCGB_00897 7.5e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IKFEDCGB_00898 3.4e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
IKFEDCGB_00899 0.0 U protein secretion
IKFEDCGB_00900 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IKFEDCGB_00901 1.1e-24
IKFEDCGB_00902 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
IKFEDCGB_00903 9.2e-256 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IKFEDCGB_00904 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IKFEDCGB_00905 6.6e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IKFEDCGB_00906 2.6e-167 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IKFEDCGB_00907 5.3e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IKFEDCGB_00908 5.1e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IKFEDCGB_00909 2.8e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IKFEDCGB_00910 2.2e-145 E Alpha beta hydrolase
IKFEDCGB_00912 3.4e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
IKFEDCGB_00913 7.7e-216 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IKFEDCGB_00914 3e-42 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IKFEDCGB_00915 9.5e-77 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IKFEDCGB_00916 1.7e-114 S VIT family
IKFEDCGB_00917 2.9e-134 deoD_1 2.4.2.3 F Phosphorylase superfamily
IKFEDCGB_00918 1.2e-21
IKFEDCGB_00919 6e-28 XK27_00085 K Transcriptional
IKFEDCGB_00920 1.2e-196 yceA S Belongs to the UPF0176 family
IKFEDCGB_00921 5.2e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IKFEDCGB_00922 1.9e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IKFEDCGB_00923 0.0 lmrA V abc transporter atp-binding protein
IKFEDCGB_00924 0.0 mdlB V abc transporter atp-binding protein
IKFEDCGB_00925 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IKFEDCGB_00926 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IKFEDCGB_00927 3e-202 V permease protein
IKFEDCGB_00928 2.3e-122 macB V ABC transporter, ATP-binding protein
IKFEDCGB_00929 8.8e-181 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IKFEDCGB_00930 2.2e-126 2.1.1.223 S Putative SAM-dependent methyltransferase
IKFEDCGB_00931 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
IKFEDCGB_00932 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
IKFEDCGB_00933 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IKFEDCGB_00934 8.1e-222 pyrP F uracil Permease
IKFEDCGB_00935 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IKFEDCGB_00936 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IKFEDCGB_00937 2.2e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IKFEDCGB_00938 4.7e-168 fhuR K transcriptional regulator (lysR family)
IKFEDCGB_00940 5.9e-16
IKFEDCGB_00941 6e-66 K Helix-turn-helix
IKFEDCGB_00945 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IKFEDCGB_00946 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
IKFEDCGB_00947 6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
IKFEDCGB_00948 7.9e-255 cycA E permease
IKFEDCGB_00949 1.7e-38 ynzC S UPF0291 protein
IKFEDCGB_00950 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IKFEDCGB_00951 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IKFEDCGB_00952 6.6e-221 S membrane
IKFEDCGB_00953 6.8e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IKFEDCGB_00954 3.5e-294 nptA P COG1283 Na phosphate symporter
IKFEDCGB_00955 6.1e-114 3.4.17.14, 3.5.1.28 NU amidase activity
IKFEDCGB_00956 2.7e-75 S Bacterial inner membrane protein
IKFEDCGB_00957 1.2e-141 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
IKFEDCGB_00958 1.3e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
IKFEDCGB_00959 3.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IKFEDCGB_00960 1.2e-54 yabA L Involved in initiation control of chromosome replication
IKFEDCGB_00961 5.8e-133 yaaT S stage 0 sporulation protein
IKFEDCGB_00962 1.1e-158 holB 2.7.7.7 L dna polymerase iii
IKFEDCGB_00963 1.3e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IKFEDCGB_00965 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IKFEDCGB_00966 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IKFEDCGB_00967 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IKFEDCGB_00968 3.5e-217 ftsW D Belongs to the SEDS family
IKFEDCGB_00969 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IKFEDCGB_00970 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IKFEDCGB_00971 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IKFEDCGB_00972 5e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IKFEDCGB_00973 2.5e-84 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IKFEDCGB_00974 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IKFEDCGB_00975 1.7e-120 atpB C it plays a direct role in the translocation of protons across the membrane
IKFEDCGB_00976 4.9e-17 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IKFEDCGB_00977 8.3e-181 femA 2.3.2.10, 2.3.2.16 V FemAB family
IKFEDCGB_00985 8e-14
IKFEDCGB_00986 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
IKFEDCGB_00987 0.0 3.5.1.28 M domain protein
IKFEDCGB_00988 1.5e-135 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
IKFEDCGB_00989 7e-93 maa 2.3.1.79 GK Maltose O-acetyltransferase
IKFEDCGB_00990 1.2e-62 rmaI K Transcriptional regulator, MarR family
IKFEDCGB_00991 1.5e-234 EGP Major facilitator Superfamily
IKFEDCGB_00992 1.6e-132 XK27_00785 S CAAX protease self-immunity
IKFEDCGB_00993 1.4e-206 3.5.1.28 NU GBS Bsp-like repeat
IKFEDCGB_00994 5.1e-15
IKFEDCGB_00996 1.4e-225 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
IKFEDCGB_00997 4.4e-138 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IKFEDCGB_00998 3.3e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
IKFEDCGB_00999 5e-182 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IKFEDCGB_01000 4.6e-219 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IKFEDCGB_01001 1.1e-122 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IKFEDCGB_01002 1.8e-204 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IKFEDCGB_01003 6.3e-133 yxkH G deacetylase
IKFEDCGB_01004 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IKFEDCGB_01005 5.9e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IKFEDCGB_01006 2.8e-149 rarD S Transporter
IKFEDCGB_01007 2.9e-15 T peptidase
IKFEDCGB_01008 1.4e-14 coiA 3.6.4.12 S Competence protein
IKFEDCGB_01011 3.8e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IKFEDCGB_01012 8.9e-96 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IKFEDCGB_01013 8.9e-159
IKFEDCGB_01014 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IKFEDCGB_01015 2.1e-100 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IKFEDCGB_01016 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IKFEDCGB_01017 1.6e-293 S dextransucrase activity
IKFEDCGB_01018 3.3e-176 S dextransucrase activity
IKFEDCGB_01019 0.0 M Putative cell wall binding repeat
IKFEDCGB_01020 1.2e-224 S dextransucrase activity
IKFEDCGB_01022 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IKFEDCGB_01023 2.8e-163 mleP S auxin efflux carrier
IKFEDCGB_01024 8.4e-309 sfcA 1.1.1.38, 4.1.1.101 C malic enzyme
IKFEDCGB_01025 2.1e-47 K Helix-turn-helix
IKFEDCGB_01026 7.9e-120 mleR K malolactic fermentation system
IKFEDCGB_01028 1.6e-49 bta 1.8.1.8 CO cell redox homeostasis
IKFEDCGB_01029 4.8e-59 L thioesterase
IKFEDCGB_01030 9.5e-141 S Macro domain protein
IKFEDCGB_01031 2.4e-50 trxA O Belongs to the thioredoxin family
IKFEDCGB_01032 7.2e-74 yccU S CoA-binding protein
IKFEDCGB_01033 4.7e-143 tatD L Hydrolase, tatd
IKFEDCGB_01034 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IKFEDCGB_01035 2.9e-154 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IKFEDCGB_01037 9.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IKFEDCGB_01038 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IKFEDCGB_01039 2.3e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
IKFEDCGB_01040 2.1e-169 rmuC S RmuC domain protein
IKFEDCGB_01041 5.8e-177 cbf S 3'-5' exoribonuclease yhaM
IKFEDCGB_01042 4e-142 purR 2.4.2.7 F operon repressor
IKFEDCGB_01043 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IKFEDCGB_01044 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IKFEDCGB_01045 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IKFEDCGB_01046 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
IKFEDCGB_01047 2.1e-115
IKFEDCGB_01048 2.2e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IKFEDCGB_01049 2.5e-86 S Fusaric acid resistance protein-like
IKFEDCGB_01050 8.5e-63 glnR K Transcriptional regulator
IKFEDCGB_01051 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
IKFEDCGB_01052 2.3e-113 pscB M CHAP domain protein
IKFEDCGB_01053 7.4e-80 hmpT S cog cog4720
IKFEDCGB_01054 3.1e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
IKFEDCGB_01055 1e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IKFEDCGB_01056 4.2e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IKFEDCGB_01057 2.3e-302 dnaK O Heat shock 70 kDa protein
IKFEDCGB_01058 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IKFEDCGB_01059 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IKFEDCGB_01060 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
IKFEDCGB_01061 4.8e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IKFEDCGB_01062 4.3e-132 ais G Phosphoglycerate mutase
IKFEDCGB_01063 2.3e-243 XK27_08635 S UPF0210 protein
IKFEDCGB_01064 6.1e-39 gcvR T UPF0237 protein
IKFEDCGB_01065 3.3e-233 capA M Bacterial capsule synthesis protein
IKFEDCGB_01066 8.6e-148 srtB 3.4.22.70 S Sortase family
IKFEDCGB_01068 1.5e-29 K Helix-turn-helix domain
IKFEDCGB_01069 1.3e-17
IKFEDCGB_01070 5.9e-123 L Helix-turn-helix domain
IKFEDCGB_01071 1.2e-99 M Putative cell wall binding repeat
IKFEDCGB_01072 5.5e-227 M Putative cell wall binding repeat
IKFEDCGB_01073 1.2e-91 S dextransucrase activity
IKFEDCGB_01074 2.4e-233 tcdB S dextransucrase activity
IKFEDCGB_01075 0.0 S dextransucrase activity
IKFEDCGB_01076 7.2e-144 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IKFEDCGB_01077 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
IKFEDCGB_01078 0.0 ydaO E amino acid
IKFEDCGB_01079 7.4e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IKFEDCGB_01080 1.5e-36 ylqC L Belongs to the UPF0109 family
IKFEDCGB_01081 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IKFEDCGB_01083 1.3e-211 2.7.13.3 T protein histidine kinase activity
IKFEDCGB_01084 8.4e-123 agrA KT phosphorelay signal transduction system
IKFEDCGB_01085 4.2e-165 O protein import
IKFEDCGB_01086 1.3e-258 S dextransucrase activity
IKFEDCGB_01087 1.9e-11
IKFEDCGB_01088 3.3e-23
IKFEDCGB_01089 2.7e-13
IKFEDCGB_01090 1.8e-14
IKFEDCGB_01091 4.1e-18
IKFEDCGB_01092 4.5e-37
IKFEDCGB_01093 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
IKFEDCGB_01094 5e-129 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IKFEDCGB_01095 1.6e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IKFEDCGB_01096 2.2e-176 prmA J Ribosomal protein L11 methyltransferase
IKFEDCGB_01097 1.2e-139 2.7.7.7 L Domain of unknown function (DUF4357)
IKFEDCGB_01098 3.9e-75 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
IKFEDCGB_01099 5.5e-83 XK27_03960 S Protein of unknown function (DUF3013)
IKFEDCGB_01100 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IKFEDCGB_01101 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IKFEDCGB_01102 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IKFEDCGB_01103 1.6e-135 ykuT M mechanosensitive ion channel
IKFEDCGB_01104 9.5e-86 sigH K DNA-templated transcription, initiation
IKFEDCGB_01106 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
IKFEDCGB_01107 2.6e-147 sdaAA 4.3.1.17 E L-serine dehydratase
IKFEDCGB_01108 1.5e-118 sdaAB 4.3.1.17 E L-serine dehydratase
IKFEDCGB_01109 4.4e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
IKFEDCGB_01110 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IKFEDCGB_01111 1.5e-36 L RePlication protein
IKFEDCGB_01112 1.2e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IKFEDCGB_01113 9.1e-83 nrdI F Belongs to the NrdI family
IKFEDCGB_01114 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IKFEDCGB_01115 4.4e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IKFEDCGB_01116 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IKFEDCGB_01117 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IKFEDCGB_01118 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IKFEDCGB_01119 4e-105 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IKFEDCGB_01120 1.7e-181 yhjX P Major Facilitator
IKFEDCGB_01121 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IKFEDCGB_01122 7.1e-72 V VanZ like family
IKFEDCGB_01123 4.2e-177 D nuclear chromosome segregation
IKFEDCGB_01124 1e-123 glnQ E abc transporter atp-binding protein
IKFEDCGB_01125 1.1e-270 glnP P ABC transporter
IKFEDCGB_01126 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IKFEDCGB_01127 2.4e-17 S Protein of unknown function (DUF3021)
IKFEDCGB_01128 1.6e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IKFEDCGB_01129 4.3e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
IKFEDCGB_01130 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IKFEDCGB_01131 9.1e-234 sufD O assembly protein SufD
IKFEDCGB_01132 1.1e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IKFEDCGB_01133 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
IKFEDCGB_01134 2.9e-273 sufB O assembly protein SufB
IKFEDCGB_01135 8e-26
IKFEDCGB_01136 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IKFEDCGB_01137 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IKFEDCGB_01138 1.6e-71 adcR K transcriptional
IKFEDCGB_01139 5.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
IKFEDCGB_01140 5.1e-129 adcB P ABC transporter (Permease
IKFEDCGB_01141 3.2e-159 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IKFEDCGB_01142 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
IKFEDCGB_01143 1.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
IKFEDCGB_01144 4.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
IKFEDCGB_01145 1.4e-142 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IKFEDCGB_01146 0.0 srlM 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
IKFEDCGB_01147 6.8e-84 gutM K phosphoenolpyruvate-dependent sugar phosphotransferase system
IKFEDCGB_01148 1.1e-95 srlA G PTS system glucitol sorbitol-specific
IKFEDCGB_01149 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
IKFEDCGB_01150 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
IKFEDCGB_01151 8.1e-16 tnp* L An automated process has identified a potential problem with this gene model
IKFEDCGB_01152 9.2e-59 L MULE transposase domain
IKFEDCGB_01153 4.2e-108 L Transposase IS116 IS110 IS902
IKFEDCGB_01154 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IKFEDCGB_01155 2.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
IKFEDCGB_01156 1.4e-153 Z012_04635 K sequence-specific DNA binding
IKFEDCGB_01157 1.1e-276 V ABC transporter
IKFEDCGB_01158 6.1e-126 yeeN K transcriptional regulatory protein
IKFEDCGB_01159 5.9e-47 yajC U protein transport
IKFEDCGB_01160 2e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IKFEDCGB_01161 5.5e-144 cdsA 2.7.7.41 S Belongs to the CDS family
IKFEDCGB_01162 3e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IKFEDCGB_01163 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IKFEDCGB_01164 0.0 WQ51_06230 S ABC transporter
IKFEDCGB_01165 1.4e-142 cmpC S abc transporter atp-binding protein
IKFEDCGB_01166 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IKFEDCGB_01167 2.4e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IKFEDCGB_01169 1e-42
IKFEDCGB_01170 7.6e-55 S TM2 domain
IKFEDCGB_01171 6.8e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IKFEDCGB_01172 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IKFEDCGB_01173 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IKFEDCGB_01174 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
IKFEDCGB_01175 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
IKFEDCGB_01176 1.2e-72 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
IKFEDCGB_01177 4.6e-146 cof S Sucrose-6F-phosphate phosphohydrolase
IKFEDCGB_01178 6.5e-134 glcR K transcriptional regulator (DeoR family)
IKFEDCGB_01179 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IKFEDCGB_01180 2.1e-38 yjdF S Protein of unknown function (DUF2992)
IKFEDCGB_01181 9.2e-153 cylA V abc transporter atp-binding protein
IKFEDCGB_01182 1.8e-124 cylB V ABC-2 type transporter
IKFEDCGB_01183 9e-75 K COG3279 Response regulator of the LytR AlgR family
IKFEDCGB_01184 5.2e-32 S Protein of unknown function (DUF3021)
IKFEDCGB_01185 1.8e-122 mta K Transcriptional
IKFEDCGB_01186 2.1e-120 yhcA V abc transporter atp-binding protein
IKFEDCGB_01187 1.4e-216 macB_2 V FtsX-like permease family
IKFEDCGB_01188 3.3e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IKFEDCGB_01189 2.2e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IKFEDCGB_01190 1.4e-72 yhaI S Protein of unknown function (DUF805)
IKFEDCGB_01191 3.2e-253 pepC 3.4.22.40 E aminopeptidase
IKFEDCGB_01192 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IKFEDCGB_01193 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IKFEDCGB_01194 5.4e-92 ypsA S Belongs to the UPF0398 family
IKFEDCGB_01195 9.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IKFEDCGB_01196 3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IKFEDCGB_01197 2.8e-277 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
IKFEDCGB_01198 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
IKFEDCGB_01199 4.8e-22
IKFEDCGB_01200 3.4e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IKFEDCGB_01201 4.2e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
IKFEDCGB_01202 2.6e-296 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IKFEDCGB_01203 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IKFEDCGB_01204 3.4e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IKFEDCGB_01205 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IKFEDCGB_01206 1e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IKFEDCGB_01207 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
IKFEDCGB_01208 7.9e-99 ybhL S Belongs to the BI1 family
IKFEDCGB_01209 4.2e-12 ycdA S Domain of unknown function (DUF4352)
IKFEDCGB_01210 9e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IKFEDCGB_01211 1.8e-90 K transcriptional regulator
IKFEDCGB_01212 1.6e-36 yneF S UPF0154 protein
IKFEDCGB_01213 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IKFEDCGB_01214 1.7e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IKFEDCGB_01215 9.6e-97 XK27_09740 S Phosphoesterase
IKFEDCGB_01216 8.3e-87 ykuL S CBS domain
IKFEDCGB_01217 7e-128 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
IKFEDCGB_01218 1.1e-119 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IKFEDCGB_01219 6.9e-96 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IKFEDCGB_01220 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IKFEDCGB_01221 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
IKFEDCGB_01222 4.2e-259 trkH P Cation transport protein
IKFEDCGB_01223 5e-246 trkA P Potassium transporter peripheral membrane component
IKFEDCGB_01224 8.2e-93 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IKFEDCGB_01225 2.7e-89 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IKFEDCGB_01226 4e-108 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
IKFEDCGB_01227 6e-155 K sequence-specific DNA binding
IKFEDCGB_01228 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IKFEDCGB_01229 3.2e-53 yhaI L Membrane
IKFEDCGB_01230 2.9e-103 S Domain of unknown function (DUF4173)
IKFEDCGB_01231 3.8e-117 S Domain of unknown function (DUF4173)
IKFEDCGB_01232 6.8e-95 ureI S AmiS/UreI family transporter
IKFEDCGB_01233 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IKFEDCGB_01234 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IKFEDCGB_01235 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IKFEDCGB_01236 6.6e-78 ureE O enzyme active site formation
IKFEDCGB_01237 1.7e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IKFEDCGB_01238 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IKFEDCGB_01239 5.4e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IKFEDCGB_01240 6.7e-176 cbiM P biosynthesis protein CbiM
IKFEDCGB_01241 3.4e-130 P Cobalt transport protein
IKFEDCGB_01242 5.3e-130 cbiO P ABC transporter
IKFEDCGB_01243 6.3e-138 ET ABC transporter substrate-binding protein
IKFEDCGB_01244 4.6e-163 metQ M Belongs to the NlpA lipoprotein family
IKFEDCGB_01245 2.8e-260 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
IKFEDCGB_01246 2.7e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IKFEDCGB_01247 1.2e-99 metI P ABC transporter (Permease
IKFEDCGB_01248 1.3e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IKFEDCGB_01249 7.1e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
IKFEDCGB_01250 3e-93 S UPF0397 protein
IKFEDCGB_01251 3.5e-310 ykoD P abc transporter atp-binding protein
IKFEDCGB_01252 4.5e-149 cbiQ P cobalt transport
IKFEDCGB_01253 3e-119 ktrA P COG0569 K transport systems, NAD-binding component
IKFEDCGB_01254 3.5e-231 P COG0168 Trk-type K transport systems, membrane components
IKFEDCGB_01255 2.1e-126 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
IKFEDCGB_01256 6.9e-90 yceD K metal-binding, possibly nucleic acid-binding protein
IKFEDCGB_01257 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKFEDCGB_01258 1.6e-277 T PhoQ Sensor
IKFEDCGB_01259 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IKFEDCGB_01260 2.3e-215 dnaB L Replication initiation and membrane attachment
IKFEDCGB_01261 4.4e-166 dnaI L Primosomal protein DnaI
IKFEDCGB_01262 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IKFEDCGB_01263 1.5e-112
IKFEDCGB_01264 5.7e-236 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IKFEDCGB_01265 5.5e-62 manO S protein conserved in bacteria
IKFEDCGB_01266 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
IKFEDCGB_01267 7.7e-117 manM G pts system
IKFEDCGB_01268 4.9e-174 manL 2.7.1.191 G pts system
IKFEDCGB_01269 2.2e-66 manO S Protein conserved in bacteria
IKFEDCGB_01270 5.3e-159 manN G PTS system mannose fructose sorbose family IID component
IKFEDCGB_01271 3.4e-133 manY G pts system
IKFEDCGB_01272 6.2e-169 manL 2.7.1.191 G pts system
IKFEDCGB_01273 1.3e-136 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
IKFEDCGB_01274 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
IKFEDCGB_01275 1.6e-247 pbuO S permease
IKFEDCGB_01276 1.2e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
IKFEDCGB_01277 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
IKFEDCGB_01278 4.8e-187 brpA K Transcriptional
IKFEDCGB_01279 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
IKFEDCGB_01280 4e-199 nusA K Participates in both transcription termination and antitermination
IKFEDCGB_01281 2.3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
IKFEDCGB_01282 1.4e-41 ylxQ J ribosomal protein
IKFEDCGB_01283 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IKFEDCGB_01284 1.9e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IKFEDCGB_01285 8.5e-99 yvdD 3.2.2.10 S Belongs to the LOG family
IKFEDCGB_01286 4.5e-269 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IKFEDCGB_01287 2.2e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
IKFEDCGB_01288 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
IKFEDCGB_01289 1.4e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
IKFEDCGB_01290 5.3e-220 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IKFEDCGB_01291 3e-296 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
IKFEDCGB_01292 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
IKFEDCGB_01293 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IKFEDCGB_01294 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IKFEDCGB_01295 3.2e-72 ylbF S Belongs to the UPF0342 family
IKFEDCGB_01296 7.1e-46 ylbG S UPF0298 protein
IKFEDCGB_01297 5.3e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
IKFEDCGB_01298 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
IKFEDCGB_01299 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
IKFEDCGB_01300 4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
IKFEDCGB_01301 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IKFEDCGB_01302 6.6e-111 acuB S CBS domain
IKFEDCGB_01303 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IKFEDCGB_01304 2.2e-108 yvyE 3.4.13.9 S YigZ family
IKFEDCGB_01305 1.6e-236 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IKFEDCGB_01306 3.4e-99 comFC K competence protein
IKFEDCGB_01307 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IKFEDCGB_01309 1.5e-12
IKFEDCGB_01310 3.3e-46 L COG3547 Transposase and inactivated derivatives
IKFEDCGB_01311 4.5e-38 M domain, Protein
IKFEDCGB_01313 3.3e-51 M domain, Protein
IKFEDCGB_01315 1.5e-101 cadD P cadmium resistance
IKFEDCGB_01316 4.5e-55 cadC K Bacterial regulatory protein, arsR family
IKFEDCGB_01317 4.1e-15
IKFEDCGB_01318 9.2e-50 yiiE S protein homotetramerization
IKFEDCGB_01319 4.1e-42 int2 L Belongs to the 'phage' integrase family
IKFEDCGB_01320 2.2e-98 M1-798 K Rhodanese Homology Domain
IKFEDCGB_01321 5.5e-47 trxA O Belongs to the thioredoxin family
IKFEDCGB_01322 4.8e-160 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IKFEDCGB_01324 7.6e-51 frnE Q DSBA-like thioredoxin domain
IKFEDCGB_01326 1.5e-15 S Protein of unknown function (DUF1211)
IKFEDCGB_01327 4.6e-202 S Protein of unknown function DUF262
IKFEDCGB_01328 1.2e-151 S Protein of unknown function DUF262
IKFEDCGB_01329 3.8e-78 mutT 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IKFEDCGB_01330 3.4e-78 3.4.21.89 S RDD family
IKFEDCGB_01331 8.3e-30 K sequence-specific DNA binding
IKFEDCGB_01332 6.6e-50 ywrO S general stress protein
IKFEDCGB_01333 1.3e-224 L the current gene model (or a revised gene model) may contain a frame shift
IKFEDCGB_01334 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IKFEDCGB_01335 2.4e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
IKFEDCGB_01336 1.5e-223 cinA 3.5.1.42 S Belongs to the CinA family
IKFEDCGB_01337 6.8e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IKFEDCGB_01338 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
IKFEDCGB_01340 1.2e-32 glnQ 3.6.3.21 E abc transporter atp-binding protein
IKFEDCGB_01341 3.2e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IKFEDCGB_01342 3.6e-115 gltJ P ABC transporter (Permease
IKFEDCGB_01343 3.6e-280 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IKFEDCGB_01345 9e-160 yeiH S Membrane
IKFEDCGB_01346 9.3e-127 mur1 3.4.17.14, 3.5.1.28 NU muramidase
IKFEDCGB_01347 2.9e-165 cpsY K Transcriptional regulator
IKFEDCGB_01348 2.7e-103 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IKFEDCGB_01349 2.6e-101 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IKFEDCGB_01350 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
IKFEDCGB_01351 1.4e-105 artQ P ABC transporter (Permease
IKFEDCGB_01352 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
IKFEDCGB_01353 1.3e-156 aatB ET ABC transporter substrate-binding protein
IKFEDCGB_01354 1.1e-267 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IKFEDCGB_01355 2.9e-50
IKFEDCGB_01356 1e-44
IKFEDCGB_01357 4.6e-188 adhP 1.1.1.1 C alcohol dehydrogenase
IKFEDCGB_01358 6.7e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IKFEDCGB_01359 1.9e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IKFEDCGB_01360 3.5e-126 gntR1 K transcriptional
IKFEDCGB_01361 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IKFEDCGB_01362 2.9e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IKFEDCGB_01363 5.3e-87
IKFEDCGB_01364 7e-92 niaR S small molecule binding protein (contains 3H domain)
IKFEDCGB_01365 1.6e-128 K DNA-binding helix-turn-helix protein
IKFEDCGB_01366 7.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IKFEDCGB_01367 7e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IKFEDCGB_01368 1.7e-165 GK ROK family
IKFEDCGB_01369 6e-157 dprA LU DNA protecting protein DprA
IKFEDCGB_01370 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IKFEDCGB_01371 2.7e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
IKFEDCGB_01372 5.9e-52 V ABC-2 family transporter protein
IKFEDCGB_01374 7.1e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKFEDCGB_01375 1.5e-221 T PhoQ Sensor
IKFEDCGB_01376 5.3e-256 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IKFEDCGB_01377 1.4e-220 XK27_05470 E Methionine synthase
IKFEDCGB_01378 1.3e-70 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IKFEDCGB_01379 3.5e-42 pspE P Rhodanese-like protein
IKFEDCGB_01380 8.2e-137 IQ Acetoin reductase
IKFEDCGB_01382 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IKFEDCGB_01385 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IKFEDCGB_01386 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IKFEDCGB_01387 3.2e-64 mgrA K Transcriptional regulator, MarR family
IKFEDCGB_01388 2.1e-150 C alcohol dehydrogenase
IKFEDCGB_01389 1.5e-124 proV E abc transporter atp-binding protein
IKFEDCGB_01390 7.5e-267 proWX P ABC transporter
IKFEDCGB_01391 1.6e-52 S Phenazine biosynthesis protein
IKFEDCGB_01392 1.1e-71 S Phenazine biosynthesis protein
IKFEDCGB_01393 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
IKFEDCGB_01394 1.7e-132 cbiQ P cobalt transport
IKFEDCGB_01395 2.3e-156 P abc transporter atp-binding protein
IKFEDCGB_01396 5.2e-150 cbiO2 P Zeta toxin
IKFEDCGB_01397 3.6e-114 tnp L DDE domain
IKFEDCGB_01398 2.4e-11
IKFEDCGB_01399 1.2e-66 S Protein of unknown function with HXXEE motif
IKFEDCGB_01400 1.3e-96 K Transcriptional regulator, TetR family
IKFEDCGB_01401 1e-154 czcD P cation diffusion facilitator family transporter
IKFEDCGB_01402 1e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IKFEDCGB_01403 3.4e-186 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
IKFEDCGB_01404 3.7e-235 S the current gene model (or a revised gene model) may contain a frame shift
IKFEDCGB_01405 5.4e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
IKFEDCGB_01406 6.6e-19 V Type III restriction enzyme, res subunit
IKFEDCGB_01407 1.2e-106 V Type III restriction enzyme, res subunit
IKFEDCGB_01408 1.5e-21 V Type III restriction enzyme, res subunit
IKFEDCGB_01409 1.9e-170 P abc-type fe3 -hydroxamate transport system, periplasmic component
IKFEDCGB_01410 2.4e-232 dinF V Mate efflux family protein
IKFEDCGB_01411 1.5e-270 S Psort location CytoplasmicMembrane, score
IKFEDCGB_01412 2.1e-307 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IKFEDCGB_01413 4.4e-133 S TraX protein
IKFEDCGB_01414 1e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
IKFEDCGB_01415 5e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IKFEDCGB_01416 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IKFEDCGB_01417 7.5e-113 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IKFEDCGB_01418 9.7e-36 cas1 L maintenance of DNA repeat elements
IKFEDCGB_01419 4.6e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IKFEDCGB_01420 1.6e-129 cas6 S Pfam:DUF2276
IKFEDCGB_01421 0.0 csm1 S CRISPR-associated protein Csm1 family
IKFEDCGB_01422 1.2e-61 csm2 L Pfam:DUF310
IKFEDCGB_01423 2.4e-116 csm3 L RAMP superfamily
IKFEDCGB_01424 1.9e-161 csm4 L CRISPR-associated RAMP protein, Csm4 family
IKFEDCGB_01425 2e-202 csm5 L CRISPR-associated RAMP protein, Csm5 family
IKFEDCGB_01426 1.1e-108 csm6 S Psort location Cytoplasmic, score
IKFEDCGB_01427 1.3e-147 csm6 S Psort location Cytoplasmic, score
IKFEDCGB_01428 6.5e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IKFEDCGB_01429 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IKFEDCGB_01430 5.9e-237 nylA 3.5.1.4 J Belongs to the amidase family
IKFEDCGB_01431 2.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
IKFEDCGB_01432 9.3e-81 yecS P ABC transporter (Permease
IKFEDCGB_01433 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
IKFEDCGB_01434 3.9e-176 bglC K Transcriptional regulator
IKFEDCGB_01435 1.2e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IKFEDCGB_01436 5.8e-239 agcS E (Alanine) symporter
IKFEDCGB_01437 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IKFEDCGB_01438 2.1e-238 metY 2.5.1.49 E o-acetylhomoserine
IKFEDCGB_01439 4.7e-137 S haloacid dehalogenase-like hydrolase
IKFEDCGB_01440 4.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IKFEDCGB_01441 4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
IKFEDCGB_01442 8e-35 M1-755 P Hemerythrin HHE cation binding domain protein
IKFEDCGB_01443 1.5e-234 XK27_04775 S hemerythrin HHE cation binding domain
IKFEDCGB_01444 6.9e-145 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IKFEDCGB_01445 2.4e-167 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IKFEDCGB_01446 6e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IKFEDCGB_01447 1e-44 yktA S Belongs to the UPF0223 family
IKFEDCGB_01448 7.2e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IKFEDCGB_01449 3.1e-245 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IKFEDCGB_01450 2.6e-155 pstS P phosphate
IKFEDCGB_01451 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
IKFEDCGB_01452 9.1e-156 pstA P phosphate transport system permease
IKFEDCGB_01453 4.4e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IKFEDCGB_01454 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IKFEDCGB_01455 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
IKFEDCGB_01456 0.0 pepN 3.4.11.2 E aminopeptidase
IKFEDCGB_01457 3.3e-192 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IKFEDCGB_01458 1.2e-185 lplA 6.3.1.20 H Lipoate-protein ligase
IKFEDCGB_01459 1.5e-38
IKFEDCGB_01460 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IKFEDCGB_01461 1.3e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
IKFEDCGB_01462 3e-155 malR K Transcriptional regulator
IKFEDCGB_01463 3.9e-229 malX G ABC transporter
IKFEDCGB_01464 5.7e-250 malF P ABC transporter (Permease
IKFEDCGB_01465 9.8e-152 malG P ABC transporter (Permease
IKFEDCGB_01466 4.7e-213 msmX P Belongs to the ABC transporter superfamily
IKFEDCGB_01467 9.5e-23 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IKFEDCGB_01468 6e-118 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IKFEDCGB_01469 1.6e-286 ywbL P COG0672 High-affinity Fe2 Pb2 permease
IKFEDCGB_01470 4.9e-229 ycdB P peroxidase
IKFEDCGB_01471 2.1e-144 ycdO P periplasmic lipoprotein involved in iron transport
IKFEDCGB_01472 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IKFEDCGB_01473 0.0 3.5.1.28 NU amidase activity
IKFEDCGB_01474 0.0 lpdA 1.8.1.4 C Dehydrogenase
IKFEDCGB_01475 7.6e-210 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IKFEDCGB_01476 4.1e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IKFEDCGB_01477 1.5e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IKFEDCGB_01478 8.3e-203 hpk9 2.7.13.3 T protein histidine kinase activity
IKFEDCGB_01479 7.9e-225 2.7.13.3 T protein histidine kinase activity
IKFEDCGB_01480 0.0 S the current gene model (or a revised gene model) may contain a frame shift
IKFEDCGB_01481 1.6e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IKFEDCGB_01482 1.7e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IKFEDCGB_01483 1.4e-215 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IKFEDCGB_01484 1.8e-248 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
IKFEDCGB_01485 3.6e-183 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
IKFEDCGB_01486 5.1e-156 rssA S Phospholipase, patatin family
IKFEDCGB_01487 2e-101 estA E Lysophospholipase L1 and related esterases
IKFEDCGB_01488 1.2e-283 S unusual protein kinase
IKFEDCGB_01489 4.1e-38 S granule-associated protein
IKFEDCGB_01490 2e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IKFEDCGB_01491 6.1e-197 S hmm pf01594
IKFEDCGB_01492 7.6e-106 G Belongs to the phosphoglycerate mutase family
IKFEDCGB_01493 1.4e-107 G Belongs to the phosphoglycerate mutase family
IKFEDCGB_01494 1.4e-107 pgm G Belongs to the phosphoglycerate mutase family
IKFEDCGB_01495 4.6e-138 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IKFEDCGB_01497 4.2e-176 wbbI M transferase activity, transferring glycosyl groups
IKFEDCGB_01498 2.5e-186 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
IKFEDCGB_01499 2.8e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
IKFEDCGB_01500 1.2e-245 epsU S Polysaccharide biosynthesis protein
IKFEDCGB_01501 9.2e-124 cps3F
IKFEDCGB_01502 3.1e-166 M Glycosyltransferase like family 2
IKFEDCGB_01503 3.4e-156
IKFEDCGB_01504 1.2e-120 Z012_10770 M Domain of unknown function (DUF1919)
IKFEDCGB_01505 2.2e-210 wcoF M Glycosyltransferase, group 1 family protein
IKFEDCGB_01506 6.9e-220 rgpAc GT4 M group 1 family protein
IKFEDCGB_01507 1.6e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IKFEDCGB_01508 5.9e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
IKFEDCGB_01509 1.2e-110 cps4C M biosynthesis protein
IKFEDCGB_01510 1.4e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
IKFEDCGB_01511 8.8e-249 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
IKFEDCGB_01512 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
IKFEDCGB_01513 1.8e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
IKFEDCGB_01514 6.5e-176 clcA_2 P Chloride transporter, ClC family
IKFEDCGB_01515 2.2e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IKFEDCGB_01516 1e-93 S Protein of unknown function (DUF1697)
IKFEDCGB_01517 1.6e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IKFEDCGB_01518 1.8e-119 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IKFEDCGB_01519 7.3e-253 V Glucan-binding protein C
IKFEDCGB_01520 1.4e-224 V Glucan-binding protein C
IKFEDCGB_01521 2.8e-80 L Transposase
IKFEDCGB_01522 3.9e-140 L overlaps another CDS with the same product name
IKFEDCGB_01524 1.5e-172 L Integrase
IKFEDCGB_01525 4.7e-45
IKFEDCGB_01528 4.5e-131 clpB O C-terminal, D2-small domain, of ClpB protein
IKFEDCGB_01530 2.3e-45
IKFEDCGB_01531 1.2e-53 I mechanosensitive ion channel activity
IKFEDCGB_01532 1.6e-53 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IKFEDCGB_01533 1.3e-10
IKFEDCGB_01534 4.2e-10 repA S Replication initiator protein A
IKFEDCGB_01536 2.2e-78 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IKFEDCGB_01537 1.6e-41 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IKFEDCGB_01538 5.6e-20 ilvE 2.6.1.42 E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IKFEDCGB_01539 1.7e-52 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
IKFEDCGB_01540 2.3e-29 tklB 2.2.1.1 G Transketolase, pyrimidine binding domain
IKFEDCGB_01541 1.3e-48 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IKFEDCGB_01543 1.9e-39 leuA3 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IKFEDCGB_01545 2.3e-58 aepX 2.7.7.15, 2.7.7.39, 5.4.2.9 GIM Phosphoenolpyruvate phosphomutase
IKFEDCGB_01546 5.2e-44 aepY 4.1.1.82 EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
IKFEDCGB_01547 1.5e-21 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IKFEDCGB_01548 3.7e-15 S Uncharacterised nucleotidyltransferase
IKFEDCGB_01549 1.1e-07 Q Phosphopantetheine attachment site
IKFEDCGB_01550 1.4e-47
IKFEDCGB_01551 3.2e-165 S abc transporter atp-binding protein
IKFEDCGB_01552 2e-120 S ABC transporter (permease)
IKFEDCGB_01553 5.6e-125 S ABC-2 family transporter protein
IKFEDCGB_01554 1.9e-25 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IKFEDCGB_01555 1.3e-16 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IKFEDCGB_01556 4.4e-33 fic D Fic/DOC family
IKFEDCGB_01557 6.1e-25
IKFEDCGB_01559 8.1e-29
IKFEDCGB_01560 5.5e-113 U AAA-like domain
IKFEDCGB_01562 2.1e-14
IKFEDCGB_01564 6.4e-43 xisC L viral genome integration into host DNA
IKFEDCGB_01566 1.8e-48
IKFEDCGB_01567 0.0 V Type II restriction enzyme, methylase subunits
IKFEDCGB_01570 1.4e-94 traI 5.99.1.2 L DNA topoisomerase
IKFEDCGB_01575 1.7e-15 dnaX 2.4.99.16, 2.7.7.7 GH13 D cell septum assembly
IKFEDCGB_01576 1.3e-130 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IKFEDCGB_01577 2.1e-32
IKFEDCGB_01578 2.3e-19
IKFEDCGB_01580 2.6e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IKFEDCGB_01581 1.8e-57
IKFEDCGB_01583 1.2e-19 K Helix-turn-helix XRE-family like proteins
IKFEDCGB_01584 2.4e-102 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IKFEDCGB_01588 1.9e-41
IKFEDCGB_01591 1.6e-20 XK27_10050 K Peptidase S24-like
IKFEDCGB_01592 7.4e-88 H Methyltransferase
IKFEDCGB_01593 0.0 M domain protein
IKFEDCGB_01595 0.0 XK27_00500 L the current gene model (or a revised gene model) may contain a
IKFEDCGB_01596 7.1e-55 S PcfJ-like protein
IKFEDCGB_01597 3.9e-12 S PcfK-like protein
IKFEDCGB_01598 1.6e-34 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IKFEDCGB_01600 1.1e-17
IKFEDCGB_01601 3.4e-29 dnaG L DNA primase activity
IKFEDCGB_01602 5.9e-24 soj D ATPases involved in chromosome partitioning
IKFEDCGB_01604 4.7e-08 L Psort location Cytoplasmic, score 8.96
IKFEDCGB_01605 2.5e-21 xerS L Belongs to the 'phage' integrase family
IKFEDCGB_01606 2.1e-51 spd F DNA RNA non-specific endonuclease
IKFEDCGB_01607 1.2e-52 3.5.1.28 NU GBS Bsp-like repeat
IKFEDCGB_01608 2e-118 3.5.1.28 NU GBS Bsp-like repeat
IKFEDCGB_01610 2e-99 Z012_04635 K sequence-specific DNA binding
IKFEDCGB_01611 4.2e-178 KLT serine threonine protein kinase
IKFEDCGB_01612 4.3e-140 V ABC transporter
IKFEDCGB_01614 2.2e-20 S Ribosomal protein S1-like RNA-binding domain
IKFEDCGB_01616 9.4e-128 U TraM recognition site of TraD and TraG
IKFEDCGB_01623 3.8e-187 V PFAM secretion protein HlyD family protein
IKFEDCGB_01624 1.2e-15 L Transposase, IS605 OrfB family
IKFEDCGB_01626 3.1e-32 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IKFEDCGB_01627 9.2e-65 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
IKFEDCGB_01628 4.7e-07 S ERF superfamily
IKFEDCGB_01633 2.1e-29 radC E Belongs to the UPF0758 family
IKFEDCGB_01635 3.8e-09 panZ K Acetyltransferase (GNAT) domain
IKFEDCGB_01642 8.1e-196 T PhoQ Sensor
IKFEDCGB_01643 2.5e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKFEDCGB_01644 6.3e-09 S Type-A lantibiotic
IKFEDCGB_01645 6.3e-09 S Type-A lantibiotic
IKFEDCGB_01647 0.0 lcnDR2 V Domain of unknown function (DUF4135)
IKFEDCGB_01648 3.2e-305 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IKFEDCGB_01649 1.2e-163 bcrA V abc transporter atp-binding protein
IKFEDCGB_01650 2.5e-130 S ABC-2 family transporter protein
IKFEDCGB_01651 7.6e-124 S ABC-2 family transporter protein
IKFEDCGB_01653 7.5e-300 salB V Lanthionine synthetase C-like protein
IKFEDCGB_01654 6.4e-171 L COG3547 Transposase and inactivated derivatives
IKFEDCGB_01655 5e-34 glnQ 3.6.3.21 E abc transporter atp-binding protein
IKFEDCGB_01657 3.9e-120 GM domain, Protein
IKFEDCGB_01659 1.7e-10
IKFEDCGB_01660 2.5e-185 XK27_10075 S abc transporter atp-binding protein
IKFEDCGB_01661 0.0 V abc transporter atp-binding protein
IKFEDCGB_01662 4.7e-297 V abc transporter atp-binding protein
IKFEDCGB_01663 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
IKFEDCGB_01665 1.7e-279 S Protein of unknown function (DUF3114)
IKFEDCGB_01666 7.6e-100 2.3.1.128 K Acetyltransferase GNAT Family
IKFEDCGB_01667 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IKFEDCGB_01668 1.7e-281 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
IKFEDCGB_01669 6.4e-178 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
IKFEDCGB_01670 3.5e-184 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IKFEDCGB_01671 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IKFEDCGB_01672 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IKFEDCGB_01673 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IKFEDCGB_01674 6.6e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IKFEDCGB_01675 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IKFEDCGB_01676 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IKFEDCGB_01679 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKFEDCGB_01680 1.9e-170 vraS 2.7.13.3 T Histidine kinase
IKFEDCGB_01681 1.7e-117 yvqF S Membrane
IKFEDCGB_01682 6.9e-104 kcsA P Ion transport protein
IKFEDCGB_01683 1.2e-293 prkC 2.7.11.1 KLT serine threonine protein kinase
IKFEDCGB_01684 1e-134 stp 3.1.3.16 T phosphatase
IKFEDCGB_01685 7.3e-242 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IKFEDCGB_01686 5.2e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IKFEDCGB_01687 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IKFEDCGB_01688 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
IKFEDCGB_01689 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IKFEDCGB_01690 6.8e-198 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IKFEDCGB_01691 2.8e-143 XK27_02985 S overlaps another CDS with the same product name
IKFEDCGB_01692 5e-145 supH S overlaps another CDS with the same product name
IKFEDCGB_01693 2.1e-61 yvoA_1 K Transcriptional
IKFEDCGB_01694 5.4e-119 skfE V abc transporter atp-binding protein
IKFEDCGB_01695 7.1e-128 V Psort location CytoplasmicMembrane, score
IKFEDCGB_01696 8e-171 oppF P Belongs to the ABC transporter superfamily
IKFEDCGB_01697 6e-202 oppD P Belongs to the ABC transporter superfamily
IKFEDCGB_01698 3.8e-165 amiD P ABC transporter (Permease
IKFEDCGB_01699 1.1e-275 amiC P ABC transporter (Permease
IKFEDCGB_01700 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
IKFEDCGB_01701 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IKFEDCGB_01702 4.7e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IKFEDCGB_01703 9.2e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IKFEDCGB_01704 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IKFEDCGB_01705 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
IKFEDCGB_01706 2.7e-100 yjbK S Adenylate cyclase
IKFEDCGB_01707 3.9e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IKFEDCGB_01708 3.3e-203 iscS 2.8.1.7 E Cysteine desulfurase
IKFEDCGB_01709 8.2e-60 XK27_04120 S Putative amino acid metabolism
IKFEDCGB_01710 5.6e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IKFEDCGB_01711 4.4e-129 puuD T peptidase C26
IKFEDCGB_01712 1.5e-118 radC E Belongs to the UPF0758 family
IKFEDCGB_01713 4.9e-280 rgpF M Rhamnan synthesis protein F
IKFEDCGB_01714 2.4e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IKFEDCGB_01715 8.9e-142 rgpC GM Transport permease protein
IKFEDCGB_01716 2.8e-171 rgpB GT2 M Glycosyltransferase, group 2 family protein
IKFEDCGB_01717 7e-225 rgpA GT4 M Domain of unknown function (DUF1972)
IKFEDCGB_01718 1.8e-226 GT4 M transferase activity, transferring glycosyl groups
IKFEDCGB_01719 4.3e-220 M Psort location CytoplasmicMembrane, score
IKFEDCGB_01720 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
IKFEDCGB_01721 7.2e-25
IKFEDCGB_01722 4.5e-102 M Dolichyl-phosphate-mannose-protein mannosyltransferase
IKFEDCGB_01723 2.3e-83 yghG S Acyltransferase family
IKFEDCGB_01724 2.4e-98 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IKFEDCGB_01726 4.6e-177 M Glycosyltransferase group 2 family protein
IKFEDCGB_01727 1.5e-149 GT2,GT4 M Glycosyl transferase family 2
IKFEDCGB_01728 2.2e-195 amrA S polysaccharide biosynthetic process
IKFEDCGB_01729 3.1e-08 XK27_09090 S Uncharacterized conserved protein (DUF2304)
IKFEDCGB_01730 9.8e-113 ycbB S glycosyl transferase family 2
IKFEDCGB_01731 2.8e-157 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IKFEDCGB_01732 1.6e-241
IKFEDCGB_01733 1.4e-167 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
IKFEDCGB_01734 1.4e-53 yitW K metal-sulfur cluster biosynthetic enzyme
IKFEDCGB_01735 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IKFEDCGB_01736 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IKFEDCGB_01737 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IKFEDCGB_01738 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IKFEDCGB_01739 1.9e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
IKFEDCGB_01740 1.6e-210 arcT 2.6.1.1 E Aminotransferase
IKFEDCGB_01741 6.7e-134 ET Belongs to the bacterial solute-binding protein 3 family
IKFEDCGB_01742 3.9e-137 ET ABC transporter
IKFEDCGB_01743 8.3e-84 mutT 3.6.1.55 F Nudix family
IKFEDCGB_01744 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IKFEDCGB_01746 2.1e-163 S CAAX amino terminal protease family protein
IKFEDCGB_01747 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
IKFEDCGB_01748 3.9e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
IKFEDCGB_01749 1.7e-17 XK27_00735
IKFEDCGB_01750 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IKFEDCGB_01752 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IKFEDCGB_01753 4.4e-10 O ADP-ribosylglycohydrolase
IKFEDCGB_01754 6.7e-63 paaI Q protein possibly involved in aromatic compounds catabolism
IKFEDCGB_01755 6e-61 ycaO O OsmC-like protein
IKFEDCGB_01757 7e-148 EG Permeases of the drug metabolite transporter (DMT) superfamily
IKFEDCGB_01759 8.5e-111 serB 3.1.3.3 E phosphoserine phosphatase
IKFEDCGB_01760 6.4e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IKFEDCGB_01761 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IKFEDCGB_01762 1e-96 3.1.3.18 S IA, variant 1
IKFEDCGB_01763 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IKFEDCGB_01764 5.9e-56 lrgA S Effector of murein hydrolase LrgA
IKFEDCGB_01766 2.7e-58 arsC 1.20.4.1 P Belongs to the ArsC family
IKFEDCGB_01767 4.5e-72 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
IKFEDCGB_01768 2.6e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IKFEDCGB_01769 2.5e-103 wecD M Acetyltransferase (GNAT) domain
IKFEDCGB_01770 8.8e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IKFEDCGB_01771 5.7e-158 GK ROK family
IKFEDCGB_01772 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
IKFEDCGB_01773 7.3e-145 XK27_08050 O HflC and HflK could regulate a protease
IKFEDCGB_01774 2.8e-204 potD P spermidine putrescine ABC transporter
IKFEDCGB_01775 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
IKFEDCGB_01776 1.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
IKFEDCGB_01777 2.6e-211 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IKFEDCGB_01778 5.8e-166 murB 1.3.1.98 M cell wall formation
IKFEDCGB_01779 1.6e-77 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IKFEDCGB_01780 2.5e-59 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IKFEDCGB_01781 5.3e-294 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
IKFEDCGB_01782 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IKFEDCGB_01783 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IKFEDCGB_01784 4.1e-234 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IKFEDCGB_01785 2.1e-233 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
IKFEDCGB_01787 3e-60 divIC D Septum formation initiator
IKFEDCGB_01788 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IKFEDCGB_01789 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IKFEDCGB_01790 5.2e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IKFEDCGB_01791 2.5e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IKFEDCGB_01792 3.2e-29 yyzM S Protein conserved in bacteria
IKFEDCGB_01793 4.7e-197 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IKFEDCGB_01794 2.2e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IKFEDCGB_01795 3.2e-133 parB K Belongs to the ParB family
IKFEDCGB_01796 1.5e-201 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
IKFEDCGB_01797 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IKFEDCGB_01798 2.2e-117 yoaK S Protein of unknown function (DUF1275)
IKFEDCGB_01802 0.0 XK27_10405 S Bacterial membrane protein YfhO
IKFEDCGB_01803 1.1e-305 ybiT S abc transporter atp-binding protein
IKFEDCGB_01804 7.1e-153 yvjA S membrane
IKFEDCGB_01805 8.5e-190 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IKFEDCGB_01806 5.8e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IKFEDCGB_01807 5.7e-200 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IKFEDCGB_01808 1.9e-57 yaaA S S4 domain protein YaaA
IKFEDCGB_01809 3.3e-228 ymfF S Peptidase M16
IKFEDCGB_01810 3.2e-234 ymfH S Peptidase M16
IKFEDCGB_01811 1.4e-129 S sequence-specific DNA binding
IKFEDCGB_01812 1.2e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IKFEDCGB_01813 2.7e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IKFEDCGB_01814 5.4e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IKFEDCGB_01815 2.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IKFEDCGB_01816 2.5e-61 lytE M LysM domain protein
IKFEDCGB_01817 9.3e-63 isaA GH23 M Immunodominant staphylococcal antigen A
IKFEDCGB_01818 7.8e-305 S Bacterial membrane protein, YfhO
IKFEDCGB_01819 1.9e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IKFEDCGB_01820 2.3e-97 yvbG U UPF0056 membrane protein
IKFEDCGB_01821 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IKFEDCGB_01822 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IKFEDCGB_01823 2.2e-73 rplI J binds to the 23S rRNA
IKFEDCGB_01824 6.5e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IKFEDCGB_01825 1.8e-47 veg S Biofilm formation stimulator VEG
IKFEDCGB_01826 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IKFEDCGB_01827 1.1e-10
IKFEDCGB_01828 7.7e-53 ypaA M Membrane
IKFEDCGB_01829 1.5e-92 XK27_06935 K transcriptional regulator
IKFEDCGB_01830 4.4e-157 XK27_06930 V domain protein
IKFEDCGB_01831 2.7e-101 S Putative adhesin
IKFEDCGB_01832 3.4e-58 XK27_06920 S Protein of unknown function (DUF1700)
IKFEDCGB_01833 1.3e-51 K transcriptional regulator, PadR family
IKFEDCGB_01834 4.1e-115 nudL L hydrolase
IKFEDCGB_01838 0.0
IKFEDCGB_01839 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
IKFEDCGB_01840 4.9e-148 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
IKFEDCGB_01842 5.8e-162 T Diguanylate cyclase
IKFEDCGB_01843 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IKFEDCGB_01844 9.5e-47 fruR K transcriptional
IKFEDCGB_01845 1.3e-92 L Transposase
IKFEDCGB_01846 7.3e-61 tnp* 1.1.1.193 L An automated process has identified a potential problem with this gene model
IKFEDCGB_01847 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IKFEDCGB_01848 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IKFEDCGB_01849 2.8e-218 metE 2.1.1.14 E Methionine synthase
IKFEDCGB_01850 4.4e-130 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
IKFEDCGB_01851 1.8e-237 hisS 6.1.1.21 J histidyl-tRNA synthetase
IKFEDCGB_01853 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IKFEDCGB_01854 9.3e-167 XK27_01785 S cog cog1284
IKFEDCGB_01855 4.2e-122 yaaA S Belongs to the UPF0246 family
IKFEDCGB_01856 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IKFEDCGB_01857 3.2e-89 XK27_10930 K acetyltransferase
IKFEDCGB_01858 7.5e-14
IKFEDCGB_01859 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IKFEDCGB_01860 1.2e-291 ccs S the current gene model (or a revised gene model) may contain a frame shift
IKFEDCGB_01861 2.1e-43 yrzB S Belongs to the UPF0473 family
IKFEDCGB_01862 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IKFEDCGB_01863 6.3e-44 yrzL S Belongs to the UPF0297 family
IKFEDCGB_01864 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IKFEDCGB_01865 3.5e-233 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
IKFEDCGB_01867 2.9e-215 int L Belongs to the 'phage' integrase family
IKFEDCGB_01868 1.9e-18 S Domain of unknown function (DUF3173)
IKFEDCGB_01869 6.9e-157 L Replication initiation factor
IKFEDCGB_01870 1.7e-60 K sequence-specific DNA binding
IKFEDCGB_01871 7.3e-81 S Short repeat of unknown function (DUF308)
IKFEDCGB_01872 6.8e-78 S membrane protein of uknown function UCP014873
IKFEDCGB_01873 4.9e-60 K sequence-specific DNA binding
IKFEDCGB_01874 2.1e-197 ltrA S Low temperature requirement protein
IKFEDCGB_01875 6.5e-90 adk 2.7.4.3 F topology modulation protein
IKFEDCGB_01876 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IKFEDCGB_01877 1.4e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IKFEDCGB_01878 2.8e-35 XK27_09805 S MORN repeat protein
IKFEDCGB_01879 0.0 XK27_09800 I Acyltransferase
IKFEDCGB_01880 1.1e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IKFEDCGB_01881 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
IKFEDCGB_01882 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IKFEDCGB_01883 1.7e-103 rplD J Forms part of the polypeptide exit tunnel
IKFEDCGB_01884 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IKFEDCGB_01885 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IKFEDCGB_01886 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IKFEDCGB_01887 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IKFEDCGB_01888 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IKFEDCGB_01889 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IKFEDCGB_01890 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
IKFEDCGB_01891 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IKFEDCGB_01892 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IKFEDCGB_01893 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IKFEDCGB_01894 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IKFEDCGB_01895 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IKFEDCGB_01896 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IKFEDCGB_01897 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IKFEDCGB_01898 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IKFEDCGB_01899 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IKFEDCGB_01900 1.9e-23 rpmD J ribosomal protein l30
IKFEDCGB_01901 5.7e-58 rplO J binds to the 23S rRNA
IKFEDCGB_01902 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IKFEDCGB_01903 4.7e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IKFEDCGB_01904 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IKFEDCGB_01905 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IKFEDCGB_01906 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IKFEDCGB_01907 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IKFEDCGB_01908 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IKFEDCGB_01909 4.4e-62 rplQ J ribosomal protein l17
IKFEDCGB_01910 1.2e-241 6.3.2.2 H gamma-glutamylcysteine synthetase
IKFEDCGB_01912 2e-163 fba 4.1.2.13, 4.1.2.29 G aldolase
IKFEDCGB_01915 2.5e-95 ywlG S Belongs to the UPF0340 family
IKFEDCGB_01916 7e-276 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
IKFEDCGB_01917 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IKFEDCGB_01918 0.0 pepO 3.4.24.71 O Peptidase family M13
IKFEDCGB_01919 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IKFEDCGB_01922 1.2e-274 thrC 4.2.3.1 E Threonine synthase
IKFEDCGB_01923 2.5e-223 norN V Mate efflux family protein
IKFEDCGB_01924 1.4e-57 asp S cog cog1302
IKFEDCGB_01925 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
IKFEDCGB_01926 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IKFEDCGB_01927 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
IKFEDCGB_01928 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
IKFEDCGB_01929 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IKFEDCGB_01930 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
IKFEDCGB_01931 1.4e-75 K Acetyltransferase (GNAT) domain
IKFEDCGB_01932 1.9e-141 S ABC-2 family transporter protein
IKFEDCGB_01933 5.3e-142 S ABC-2 family transporter protein
IKFEDCGB_01934 1.1e-186 S abc transporter atp-binding protein
IKFEDCGB_01935 3.3e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKFEDCGB_01936 4.6e-186 desK 2.7.13.3 T Histidine kinase
IKFEDCGB_01937 2.8e-134 yvfS V ABC-2 type transporter
IKFEDCGB_01938 8.2e-157 XK27_09825 V 'abc transporter, ATP-binding protein
IKFEDCGB_01941 2.3e-165 yocS S Transporter
IKFEDCGB_01942 2.2e-81 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
IKFEDCGB_01943 3.1e-117 yvfS V Transporter
IKFEDCGB_01944 4.5e-155 XK27_09825 V abc transporter atp-binding protein
IKFEDCGB_01945 1.4e-15 liaI KT membrane
IKFEDCGB_01946 2.2e-29 liaI KT membrane
IKFEDCGB_01947 6.1e-93 XK27_05000 S metal cluster binding
IKFEDCGB_01948 0.0 V ABC transporter (permease)
IKFEDCGB_01949 2.5e-130 macB2 V ABC transporter, ATP-binding protein
IKFEDCGB_01950 5.3e-149 T Histidine kinase
IKFEDCGB_01951 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKFEDCGB_01952 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IKFEDCGB_01953 8.5e-224 pbuX F xanthine permease
IKFEDCGB_01954 4.9e-59 pdxH S pyridoxamine 5'-phosphate oxidase
IKFEDCGB_01955 4.6e-244 norM V Multidrug efflux pump
IKFEDCGB_01957 5.3e-186 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IKFEDCGB_01958 6.4e-230 brnQ E Component of the transport system for branched-chain amino acids
IKFEDCGB_01959 1.9e-180 manA 5.3.1.8 G mannose-6-phosphate isomerase
IKFEDCGB_01960 2e-58 S Protein of unknown function (DUF3290)
IKFEDCGB_01961 6e-101 S Protein of unknown function (DUF421)
IKFEDCGB_01962 1.6e-15 csbD K CsbD-like
IKFEDCGB_01963 2.5e-84 S Carbohydrate-binding domain-containing protein Cthe_2159
IKFEDCGB_01964 2.6e-50 XK27_01300 P Protein conserved in bacteria
IKFEDCGB_01965 2.1e-215 yfnA E amino acid
IKFEDCGB_01966 0.0 S dextransucrase activity
IKFEDCGB_01967 2.8e-82 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IKFEDCGB_01968 1.5e-42 S Sugar efflux transporter for intercellular exchange
IKFEDCGB_01969 2.2e-202 P FtsX-like permease family
IKFEDCGB_01970 1e-122 V abc transporter atp-binding protein
IKFEDCGB_01971 5.8e-95 K WHG domain
IKFEDCGB_01972 8.8e-170 ydhF S Aldo keto reductase
IKFEDCGB_01973 1.1e-06 S Protein of unknown function (DUF3169)
IKFEDCGB_01974 2.5e-27 XK27_07105 K transcriptional
IKFEDCGB_01975 2.5e-36
IKFEDCGB_01976 3.3e-109 XK27_02070 S nitroreductase
IKFEDCGB_01977 7.9e-149 1.13.11.2 S glyoxalase
IKFEDCGB_01978 2.6e-74 ywnA K Transcriptional regulator
IKFEDCGB_01979 1.8e-153 E Alpha/beta hydrolase of unknown function (DUF915)
IKFEDCGB_01980 3.2e-226 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IKFEDCGB_01981 4.8e-168 bcrA V abc transporter atp-binding protein
IKFEDCGB_01982 2.3e-128 S ABC-2 family transporter protein
IKFEDCGB_01983 4.5e-147 T PhoQ Sensor
IKFEDCGB_01984 2.1e-123 T Xre family transcriptional regulator
IKFEDCGB_01985 4.1e-110 drgA C nitroreductase
IKFEDCGB_01986 1.6e-107 yoaK S Protein of unknown function (DUF1275)
IKFEDCGB_01987 7.6e-39 DJ nuclease activity
IKFEDCGB_01988 3.2e-30 XK27_10490
IKFEDCGB_01989 1.2e-157 yvgN C reductase
IKFEDCGB_01990 1.4e-209 S Tetratricopeptide repeat
IKFEDCGB_01991 0.0 lacL 3.2.1.23 G -beta-galactosidase
IKFEDCGB_01992 0.0 lacS G transporter
IKFEDCGB_01993 4.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IKFEDCGB_01994 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IKFEDCGB_01995 6.3e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IKFEDCGB_01996 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IKFEDCGB_01997 2e-175 galR K Transcriptional regulator
IKFEDCGB_01998 3.9e-306 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
IKFEDCGB_01999 2.9e-227 vncS 2.7.13.3 T Histidine kinase
IKFEDCGB_02000 2e-115 K Response regulator receiver domain protein
IKFEDCGB_02001 7.8e-239 vex3 V Efflux ABC transporter, permease protein
IKFEDCGB_02002 1.9e-107 vex2 V abc transporter atp-binding protein
IKFEDCGB_02003 5.3e-210 vex1 V Efflux ABC transporter, permease protein
IKFEDCGB_02004 1.2e-282 XK27_07020 S Belongs to the UPF0371 family
IKFEDCGB_02006 6.3e-199 gldA 1.1.1.6 C glycerol dehydrogenase
IKFEDCGB_02007 4.8e-182 XK27_10475 S oxidoreductase
IKFEDCGB_02008 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
IKFEDCGB_02009 7.6e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
IKFEDCGB_02010 2.3e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
IKFEDCGB_02011 1.4e-221 thrE K Psort location CytoplasmicMembrane, score
IKFEDCGB_02012 1.6e-133 T Ser Thr phosphatase family protein
IKFEDCGB_02013 3.2e-34 S Immunity protein 41
IKFEDCGB_02014 0.0 pepO 3.4.24.71 O Peptidase family M13
IKFEDCGB_02015 1.5e-07 S Enterocin A Immunity
IKFEDCGB_02016 4.9e-193 mccF V LD-carboxypeptidase
IKFEDCGB_02017 3.6e-15 S integral membrane protein
IKFEDCGB_02018 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
IKFEDCGB_02019 2.6e-111 yhfC S Putative membrane peptidase family (DUF2324)
IKFEDCGB_02021 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
IKFEDCGB_02022 2e-283 adcA P Belongs to the bacterial solute-binding protein 9 family
IKFEDCGB_02023 2.2e-140 XK27_10720 D peptidase activity
IKFEDCGB_02024 1.5e-274 pepD E Dipeptidase
IKFEDCGB_02025 1.3e-160 whiA K May be required for sporulation
IKFEDCGB_02026 1.4e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IKFEDCGB_02027 2e-163 rapZ S Displays ATPase and GTPase activities
IKFEDCGB_02028 9.1e-136 yejC S cyclic nucleotide-binding protein
IKFEDCGB_02029 1.1e-196 D nuclear chromosome segregation
IKFEDCGB_02030 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
IKFEDCGB_02031 1.6e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IKFEDCGB_02032 4.3e-82 queD 4.1.2.50, 4.2.3.12 H synthase
IKFEDCGB_02033 1.7e-122 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IKFEDCGB_02034 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
IKFEDCGB_02035 1.4e-18
IKFEDCGB_02036 7.1e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IKFEDCGB_02037 9.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IKFEDCGB_02038 1.1e-81 ypmB S Protein conserved in bacteria
IKFEDCGB_02039 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IKFEDCGB_02040 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IKFEDCGB_02041 2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
IKFEDCGB_02042 2.6e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
IKFEDCGB_02043 3.1e-276 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IKFEDCGB_02044 3.2e-187 tcsA S membrane
IKFEDCGB_02045 2.4e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IKFEDCGB_02046 7.9e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IKFEDCGB_02047 7.3e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IKFEDCGB_02048 5.4e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
IKFEDCGB_02049 6.2e-171 coaA 2.7.1.33 F Pantothenic acid kinase
IKFEDCGB_02050 1e-29 rpsT J Binds directly to 16S ribosomal RNA
IKFEDCGB_02051 9.5e-240 T PhoQ Sensor
IKFEDCGB_02052 2.5e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKFEDCGB_02053 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IKFEDCGB_02054 4.2e-116 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
IKFEDCGB_02055 5.7e-92 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IKFEDCGB_02056 4.1e-93 panT S ECF transporter, substrate-specific component
IKFEDCGB_02057 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IKFEDCGB_02058 1.6e-165 metF 1.5.1.20 E reductase
IKFEDCGB_02059 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IKFEDCGB_02061 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
IKFEDCGB_02062 0.0 3.6.3.8 P cation transport ATPase
IKFEDCGB_02063 5e-240 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IKFEDCGB_02064 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKFEDCGB_02065 1.2e-235 dltB M Membrane protein involved in D-alanine export
IKFEDCGB_02066 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKFEDCGB_02067 0.0 XK27_10035 V abc transporter atp-binding protein
IKFEDCGB_02068 1.3e-294 yfiB1 V abc transporter atp-binding protein
IKFEDCGB_02069 5.4e-99 pvaA M lytic transglycosylase activity
IKFEDCGB_02070 1.6e-177 ndpA S 37-kD nucleoid-associated bacterial protein
IKFEDCGB_02071 5.1e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IKFEDCGB_02072 1.7e-100 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IKFEDCGB_02073 9.8e-144 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IKFEDCGB_02074 7.3e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IKFEDCGB_02075 3e-110 tdk 2.7.1.21 F thymidine kinase
IKFEDCGB_02076 1.4e-181 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IKFEDCGB_02077 1.6e-151 gst O Glutathione S-transferase
IKFEDCGB_02078 1e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
IKFEDCGB_02079 1e-173 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IKFEDCGB_02080 4.4e-45 rpmE2 J 50S ribosomal protein L31
IKFEDCGB_02081 6.1e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
IKFEDCGB_02082 3.8e-163 ypuA S secreted protein
IKFEDCGB_02083 2.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
IKFEDCGB_02084 3.9e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
IKFEDCGB_02085 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IKFEDCGB_02086 1.6e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IKFEDCGB_02087 7.8e-255 noxE P NADH oxidase
IKFEDCGB_02088 2.5e-294 yfmM S abc transporter atp-binding protein
IKFEDCGB_02089 5.8e-81 XK27_01265 S ECF-type riboflavin transporter, S component
IKFEDCGB_02090 7e-145 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IKFEDCGB_02091 2.2e-85 S ECF-type riboflavin transporter, S component
IKFEDCGB_02093 5.7e-236 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IKFEDCGB_02094 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
IKFEDCGB_02096 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IKFEDCGB_02097 3.2e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKFEDCGB_02098 1.2e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IKFEDCGB_02099 3.8e-22 WQ51_00220 K Helix-turn-helix domain
IKFEDCGB_02100 9.1e-90 S Protein of unknown function (DUF3278)
IKFEDCGB_02101 0.0 smc D Required for chromosome condensation and partitioning
IKFEDCGB_02102 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IKFEDCGB_02103 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IKFEDCGB_02104 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IKFEDCGB_02105 2.4e-121 alkD L DNA alkylation repair enzyme
IKFEDCGB_02106 2.6e-291 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IKFEDCGB_02107 6.3e-93 pat 2.3.1.183 M acetyltransferase
IKFEDCGB_02108 8.5e-265 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IKFEDCGB_02109 1.8e-279 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
IKFEDCGB_02110 1.1e-164 tehB 2.1.1.265 PQ tellurite resistance protein tehb
IKFEDCGB_02111 3.7e-17 yjdB S Domain of unknown function (DUF4767)
IKFEDCGB_02112 4.4e-38 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKFEDCGB_02113 3.4e-109 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKFEDCGB_02115 4.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
IKFEDCGB_02116 3.7e-71 S QueT transporter
IKFEDCGB_02118 3.2e-170 yfjR K regulation of single-species biofilm formation
IKFEDCGB_02120 1.1e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IKFEDCGB_02121 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IKFEDCGB_02122 2.8e-85 ccl S cog cog4708
IKFEDCGB_02123 8.4e-160 rbn E Belongs to the UPF0761 family
IKFEDCGB_02124 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
IKFEDCGB_02125 7.3e-231 ytoI K transcriptional regulator containing CBS domains
IKFEDCGB_02126 1.2e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
IKFEDCGB_02127 1.5e-228 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IKFEDCGB_02128 0.0 comEC S Competence protein ComEC
IKFEDCGB_02129 4.4e-89 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
IKFEDCGB_02130 3.2e-141 plsC 2.3.1.51 I Acyltransferase
IKFEDCGB_02131 3.2e-143 nodB3 G deacetylase
IKFEDCGB_02132 3.4e-127 yabB 2.1.1.223 L Methyltransferase
IKFEDCGB_02133 2.3e-41 yazA L endonuclease containing a URI domain
IKFEDCGB_02134 1.5e-27 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
IKFEDCGB_02135 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IKFEDCGB_02136 1.1e-151 corA P CorA-like protein
IKFEDCGB_02137 3.3e-62 yjqA S Bacterial PH domain
IKFEDCGB_02138 6.6e-99 thiT S Thiamine transporter
IKFEDCGB_02139 1.6e-126 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IKFEDCGB_02140 8e-192 yjbB G Permeases of the major facilitator superfamily
IKFEDCGB_02141 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IKFEDCGB_02142 3.3e-118 ywaF S Integral membrane protein (intg_mem_TP0381)
IKFEDCGB_02143 4.5e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IKFEDCGB_02147 3.3e-155 cjaA ET ABC transporter substrate-binding protein
IKFEDCGB_02148 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
IKFEDCGB_02149 4.6e-107 P ABC transporter (Permease
IKFEDCGB_02150 6.6e-114 papP P ABC transporter (Permease
IKFEDCGB_02151 1.3e-190 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IKFEDCGB_02152 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
IKFEDCGB_02153 0.0 copA 3.6.3.54 P P-type ATPase
IKFEDCGB_02154 8e-73 copY K negative regulation of transcription, DNA-templated
IKFEDCGB_02157 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IKFEDCGB_02158 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IKFEDCGB_02159 4.8e-97 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
IKFEDCGB_02160 1.8e-131 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IKFEDCGB_02161 8.7e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IKFEDCGB_02162 1.4e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
IKFEDCGB_02163 5.3e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IKFEDCGB_02164 1.5e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
IKFEDCGB_02165 4.9e-58
IKFEDCGB_02166 0.0 ctpE P E1-E2 ATPase
IKFEDCGB_02167 5.8e-46
IKFEDCGB_02168 9.5e-49
IKFEDCGB_02169 1.7e-45
IKFEDCGB_02170 2.1e-81
IKFEDCGB_02171 7.9e-287 E Zn peptidase
IKFEDCGB_02172 0.0 res 3.1.21.5 L Type III restriction enzyme, res subunit
IKFEDCGB_02173 0.0 2.1.1.72 L DNA methylase
IKFEDCGB_02174 3.2e-32 S Sigma-70, region 4
IKFEDCGB_02175 2.8e-46
IKFEDCGB_02176 7.4e-192 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IKFEDCGB_02177 4.1e-75
IKFEDCGB_02178 5.4e-104 S Plasmid replication protein
IKFEDCGB_02179 2.2e-22 S Domain of unknown function (DUF3173)
IKFEDCGB_02180 1.8e-212 L Belongs to the 'phage' integrase family
IKFEDCGB_02181 3.9e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IKFEDCGB_02183 9.5e-124 V abc transporter atp-binding protein
IKFEDCGB_02184 0.0 V ABC transporter (Permease
IKFEDCGB_02185 9.9e-124 K transcriptional regulator, MerR family
IKFEDCGB_02186 1.2e-103 dnaQ 2.7.7.7 L DNA polymerase III
IKFEDCGB_02187 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
IKFEDCGB_02188 9.6e-64 XK27_02560 S cog cog2151
IKFEDCGB_02189 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IKFEDCGB_02190 1.8e-220 ytfP S Flavoprotein
IKFEDCGB_02192 4.5e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IKFEDCGB_02193 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
IKFEDCGB_02194 1e-174 ecsB U Bacterial ABC transporter protein EcsB
IKFEDCGB_02195 1.3e-131 ecsA V abc transporter atp-binding protein
IKFEDCGB_02196 3.3e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IKFEDCGB_02198 4.1e-43
IKFEDCGB_02199 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
IKFEDCGB_02200 1e-43 yoeB S Addiction module toxin, Txe YoeB family
IKFEDCGB_02201 1.7e-38 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)