ORF_ID e_value Gene_name EC_number CAZy COGs Description
HGCPKCDE_00001 4.1e-105 L Belongs to the 'phage' integrase family
HGCPKCDE_00002 0.0 L Tn3 transposase DDE domain
HGCPKCDE_00003 2.3e-67 L Transposase
HGCPKCDE_00004 4.6e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HGCPKCDE_00005 3.9e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HGCPKCDE_00006 1.2e-84 gerD
HGCPKCDE_00007 3e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HGCPKCDE_00008 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HGCPKCDE_00009 9.7e-66 ybaK S Protein of unknown function (DUF2521)
HGCPKCDE_00010 4.5e-143 ybaJ Q Methyltransferase domain
HGCPKCDE_00011 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HGCPKCDE_00012 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HGCPKCDE_00013 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HGCPKCDE_00014 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGCPKCDE_00015 1.1e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGCPKCDE_00016 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGCPKCDE_00017 3.6e-58 rplQ J Ribosomal protein L17
HGCPKCDE_00018 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGCPKCDE_00019 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HGCPKCDE_00020 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HGCPKCDE_00021 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HGCPKCDE_00022 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HGCPKCDE_00023 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HGCPKCDE_00024 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HGCPKCDE_00025 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HGCPKCDE_00026 1.8e-72 rplO J binds to the 23S rRNA
HGCPKCDE_00027 1.9e-23 rpmD J Ribosomal protein L30
HGCPKCDE_00028 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HGCPKCDE_00029 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HGCPKCDE_00030 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HGCPKCDE_00031 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HGCPKCDE_00032 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGCPKCDE_00033 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HGCPKCDE_00034 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HGCPKCDE_00035 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HGCPKCDE_00036 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HGCPKCDE_00037 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HGCPKCDE_00038 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HGCPKCDE_00039 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HGCPKCDE_00040 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HGCPKCDE_00041 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HGCPKCDE_00042 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HGCPKCDE_00043 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HGCPKCDE_00044 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
HGCPKCDE_00045 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HGCPKCDE_00046 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HGCPKCDE_00047 3.1e-178 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HGCPKCDE_00048 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HGCPKCDE_00049 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGCPKCDE_00050 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HGCPKCDE_00051 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HGCPKCDE_00052 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HGCPKCDE_00053 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGCPKCDE_00054 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGCPKCDE_00055 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HGCPKCDE_00056 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HGCPKCDE_00057 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HGCPKCDE_00058 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HGCPKCDE_00059 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HGCPKCDE_00060 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
HGCPKCDE_00061 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HGCPKCDE_00062 4.4e-115 sigH K Belongs to the sigma-70 factor family
HGCPKCDE_00063 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HGCPKCDE_00064 9.8e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGCPKCDE_00065 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HGCPKCDE_00066 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGCPKCDE_00067 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HGCPKCDE_00068 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGCPKCDE_00069 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HGCPKCDE_00070 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HGCPKCDE_00071 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HGCPKCDE_00072 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HGCPKCDE_00073 4e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HGCPKCDE_00074 0.0 clpC O Belongs to the ClpA ClpB family
HGCPKCDE_00075 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HGCPKCDE_00076 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HGCPKCDE_00077 2.9e-76 ctsR K Belongs to the CtsR family
HGCPKCDE_00078 6.7e-167 ygxA S Nucleotidyltransferase-like
HGCPKCDE_00079 9.5e-56 ygzB S UPF0295 protein
HGCPKCDE_00080 4e-80 perR P Belongs to the Fur family
HGCPKCDE_00081 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
HGCPKCDE_00082 2.6e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HGCPKCDE_00083 8.7e-180 ygaE S Membrane
HGCPKCDE_00084 9.1e-301 ygaD V ABC transporter
HGCPKCDE_00085 1.3e-104 ygaC J Belongs to the UPF0374 family
HGCPKCDE_00086 1.5e-37 ygaB S YgaB-like protein
HGCPKCDE_00087 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HGCPKCDE_00088 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCPKCDE_00089 6.9e-36 yfhS
HGCPKCDE_00090 3.3e-210 mutY L A G-specific
HGCPKCDE_00091 1.2e-185 yfhP S membrane-bound metal-dependent
HGCPKCDE_00092 0.0 yfhO S Bacterial membrane protein YfhO
HGCPKCDE_00093 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HGCPKCDE_00094 1.3e-170 yfhM S Alpha beta hydrolase
HGCPKCDE_00095 3.5e-51 yfhL S SdpI/YhfL protein family
HGCPKCDE_00096 2.4e-87 batE T Bacterial SH3 domain homologues
HGCPKCDE_00097 1.3e-44 yfhJ S WVELL protein
HGCPKCDE_00098 6.2e-20 sspK S reproduction
HGCPKCDE_00099 1.1e-209 yfhI EGP Major facilitator Superfamily
HGCPKCDE_00100 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HGCPKCDE_00101 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HGCPKCDE_00102 1.6e-171 yfhF S nucleoside-diphosphate sugar epimerase
HGCPKCDE_00104 2.1e-25 yfhD S YfhD-like protein
HGCPKCDE_00105 3.9e-107 yfhC C nitroreductase
HGCPKCDE_00106 1.8e-167 yfhB 5.3.3.17 S PhzF family
HGCPKCDE_00107 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCPKCDE_00108 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCPKCDE_00109 1.8e-176 yfiY P ABC transporter substrate-binding protein
HGCPKCDE_00110 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGCPKCDE_00111 1.1e-78 yfiV K transcriptional
HGCPKCDE_00112 3.8e-282 yfiU EGP Major facilitator Superfamily
HGCPKCDE_00113 1.2e-99 yfiT S Belongs to the metal hydrolase YfiT family
HGCPKCDE_00114 4.2e-195 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HGCPKCDE_00115 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HGCPKCDE_00116 8.3e-99 padR K transcriptional
HGCPKCDE_00117 1.5e-203 V COG0842 ABC-type multidrug transport system, permease component
HGCPKCDE_00118 1.8e-207 V ABC-2 family transporter protein
HGCPKCDE_00119 5.4e-167 V ABC transporter, ATP-binding protein
HGCPKCDE_00120 7.1e-113 KT LuxR family transcriptional regulator
HGCPKCDE_00121 3.6e-213 yxjM T Histidine kinase
HGCPKCDE_00123 2.8e-162 yfiE 1.13.11.2 S glyoxalase
HGCPKCDE_00124 6.4e-64 mhqP S DoxX
HGCPKCDE_00125 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HGCPKCDE_00126 1.4e-306 yfiB3 V ABC transporter
HGCPKCDE_00127 0.0 yobO M COG5434 Endopolygalacturonase
HGCPKCDE_00128 5.2e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCPKCDE_00129 1e-139 glvR K Helix-turn-helix domain, rpiR family
HGCPKCDE_00130 2.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HGCPKCDE_00131 1.1e-44 yfjA S Belongs to the WXG100 family
HGCPKCDE_00132 4.7e-171 yfjB
HGCPKCDE_00133 5.6e-125 yfjC
HGCPKCDE_00134 1.8e-85 S Family of unknown function (DUF5381)
HGCPKCDE_00135 4e-56 yfjF S UPF0060 membrane protein
HGCPKCDE_00136 9.8e-25 sspH S Belongs to the SspH family
HGCPKCDE_00137 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HGCPKCDE_00138 8.6e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HGCPKCDE_00139 9.3e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGCPKCDE_00140 3.6e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HGCPKCDE_00141 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HGCPKCDE_00142 6.6e-29 yfjL
HGCPKCDE_00143 2.3e-33 yfjM S Psort location Cytoplasmic, score
HGCPKCDE_00144 4.4e-28 yfjM S Psort location Cytoplasmic, score
HGCPKCDE_00145 6.2e-190 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGCPKCDE_00146 9e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGCPKCDE_00147 2.9e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HGCPKCDE_00148 1.7e-184 corA P Mediates influx of magnesium ions
HGCPKCDE_00149 2.1e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HGCPKCDE_00150 2.2e-153 pdaA G deacetylase
HGCPKCDE_00151 1.1e-26 yfjT
HGCPKCDE_00152 6e-221 yfkA S YfkB-like domain
HGCPKCDE_00153 6e-149 yfkC M Mechanosensitive ion channel
HGCPKCDE_00154 4.5e-146 yfkD S YfkD-like protein
HGCPKCDE_00155 6.1e-183 cax P COG0387 Ca2 H antiporter
HGCPKCDE_00156 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HGCPKCDE_00157 5e-08
HGCPKCDE_00158 1.3e-143 yihY S Belongs to the UPF0761 family
HGCPKCDE_00159 1.2e-49 yfkI S gas vesicle protein
HGCPKCDE_00160 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGCPKCDE_00161 1.3e-28 yfkK S Belongs to the UPF0435 family
HGCPKCDE_00162 6.8e-207 ydiM EGP Major facilitator Superfamily
HGCPKCDE_00163 1.2e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
HGCPKCDE_00164 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HGCPKCDE_00165 1.1e-124 yfkO C nitroreductase
HGCPKCDE_00166 1.8e-133 treR K transcriptional
HGCPKCDE_00167 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HGCPKCDE_00168 1.9e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCPKCDE_00169 4.1e-281 yfkQ EG Spore germination protein
HGCPKCDE_00170 5.6e-206 yfkR S spore germination
HGCPKCDE_00172 3.9e-193 E Spore germination protein
HGCPKCDE_00173 2.2e-252 agcS_1 E Sodium alanine symporter
HGCPKCDE_00174 6e-67 yhdN S Domain of unknown function (DUF1992)
HGCPKCDE_00175 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HGCPKCDE_00176 1.5e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HGCPKCDE_00177 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HGCPKCDE_00178 5.3e-50 yflH S Protein of unknown function (DUF3243)
HGCPKCDE_00179 4.1e-19 yflI
HGCPKCDE_00180 4e-18 yflJ S Protein of unknown function (DUF2639)
HGCPKCDE_00181 6.4e-122 yflK S protein conserved in bacteria
HGCPKCDE_00182 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HGCPKCDE_00183 8.1e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HGCPKCDE_00184 3.9e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HGCPKCDE_00185 8.5e-227 citM C Citrate transporter
HGCPKCDE_00186 3.7e-179 yflP S Tripartite tricarboxylate transporter family receptor
HGCPKCDE_00187 1.3e-117 citT T response regulator
HGCPKCDE_00188 2.8e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HGCPKCDE_00189 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
HGCPKCDE_00190 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HGCPKCDE_00191 7.6e-58 yflT S Heat induced stress protein YflT
HGCPKCDE_00192 2.9e-24 S Protein of unknown function (DUF3212)
HGCPKCDE_00193 3.9e-165 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HGCPKCDE_00194 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCPKCDE_00195 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCPKCDE_00196 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HGCPKCDE_00197 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
HGCPKCDE_00198 2.2e-213 G Major Facilitator Superfamily
HGCPKCDE_00199 3.6e-188 yfmJ S N-terminal domain of oxidoreductase
HGCPKCDE_00200 1.5e-77 yfmK 2.3.1.128 K acetyltransferase
HGCPKCDE_00201 1.7e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HGCPKCDE_00202 1.8e-295 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HGCPKCDE_00203 9.5e-209 yfmO EGP Major facilitator Superfamily
HGCPKCDE_00204 1.4e-69 yfmP K transcriptional
HGCPKCDE_00205 3.7e-73 yfmQ S Uncharacterised protein from bacillus cereus group
HGCPKCDE_00206 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HGCPKCDE_00207 1.1e-113 yfmS NT chemotaxis protein
HGCPKCDE_00208 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGCPKCDE_00209 8.4e-241 yfnA E amino acid
HGCPKCDE_00210 4.3e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HGCPKCDE_00211 1.7e-205 fsr P COG0477 Permeases of the major facilitator superfamily
HGCPKCDE_00212 2.5e-188 yfnD M Nucleotide-diphospho-sugar transferase
HGCPKCDE_00213 1.2e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HGCPKCDE_00214 4.2e-180 yfnF M Nucleotide-diphospho-sugar transferase
HGCPKCDE_00215 1.9e-172 yfnG 4.2.1.45 M dehydratase
HGCPKCDE_00216 3.3e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
HGCPKCDE_00217 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HGCPKCDE_00218 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HGCPKCDE_00219 3.6e-199 yetN S Protein of unknown function (DUF3900)
HGCPKCDE_00220 6.6e-212 yetM CH FAD binding domain
HGCPKCDE_00221 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HGCPKCDE_00222 1.2e-158 yetK EG EamA-like transporter family
HGCPKCDE_00223 2.6e-104 yetJ S Belongs to the BI1 family
HGCPKCDE_00224 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HGCPKCDE_00225 7.1e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGCPKCDE_00226 2.4e-34
HGCPKCDE_00227 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCPKCDE_00228 8.2e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HGCPKCDE_00229 4e-122 yetF S membrane
HGCPKCDE_00230 1.1e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HGCPKCDE_00231 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HGCPKCDE_00232 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HGCPKCDE_00233 2.8e-290 lplA G Bacterial extracellular solute-binding protein
HGCPKCDE_00234 0.0 yetA
HGCPKCDE_00235 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HGCPKCDE_00236 8.8e-124 yesY E GDSL-like Lipase/Acylhydrolase
HGCPKCDE_00237 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HGCPKCDE_00238 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HGCPKCDE_00239 6.3e-111 yesV S Protein of unknown function, DUF624
HGCPKCDE_00240 2.7e-128 yesU S Domain of unknown function (DUF1961)
HGCPKCDE_00241 9.7e-129 E GDSL-like Lipase/Acylhydrolase
HGCPKCDE_00242 0.0 yesS K Transcriptional regulator
HGCPKCDE_00243 3.3e-197 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HGCPKCDE_00244 5.9e-163 yesQ P Binding-protein-dependent transport system inner membrane component
HGCPKCDE_00245 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
HGCPKCDE_00246 8e-246 yesO G Bacterial extracellular solute-binding protein
HGCPKCDE_00247 1.8e-201 yesN K helix_turn_helix, arabinose operon control protein
HGCPKCDE_00248 0.0 yesM 2.7.13.3 T Histidine kinase
HGCPKCDE_00249 5.9e-101 yesL S Protein of unknown function, DUF624
HGCPKCDE_00251 4.8e-99 yesJ K Acetyltransferase (GNAT) family
HGCPKCDE_00252 5.2e-104 cotJC P Spore Coat
HGCPKCDE_00253 1.5e-45 cotJB S CotJB protein
HGCPKCDE_00254 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HGCPKCDE_00255 6.5e-151 yesF GM NAD(P)H-binding
HGCPKCDE_00256 9.1e-80 yesE S SnoaL-like domain
HGCPKCDE_00257 9.4e-101 dhaR3 K Transcriptional regulator
HGCPKCDE_00259 2.7e-126 yeeN K transcriptional regulatory protein
HGCPKCDE_00261 3.7e-210 S Tetratricopeptide repeat
HGCPKCDE_00262 2.1e-51
HGCPKCDE_00263 7.6e-97 L endonuclease activity
HGCPKCDE_00265 2.7e-194 yobL S Bacterial EndoU nuclease
HGCPKCDE_00266 1.3e-20 S Colicin immunity protein / pyocin immunity protein
HGCPKCDE_00267 1.5e-11 S Protein of unknown function, DUF600
HGCPKCDE_00268 3.7e-40 S Immunity protein 22
HGCPKCDE_00270 1.5e-59 S Tetratricopeptide repeat
HGCPKCDE_00273 1.1e-24
HGCPKCDE_00274 7.8e-42 3.6.4.12 L UvrD/REP helicase N-terminal domain
HGCPKCDE_00275 2.1e-285 L AAA ATPase domain
HGCPKCDE_00276 4.1e-48 K Putative DNA-binding domain
HGCPKCDE_00277 3.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGCPKCDE_00278 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HGCPKCDE_00279 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HGCPKCDE_00280 1.3e-148 yerO K Transcriptional regulator
HGCPKCDE_00281 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGCPKCDE_00282 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HGCPKCDE_00283 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGCPKCDE_00284 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGCPKCDE_00285 1.6e-123 sapB S MgtC SapB transporter
HGCPKCDE_00286 3.2e-197 yerI S homoserine kinase type II (protein kinase fold)
HGCPKCDE_00287 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
HGCPKCDE_00288 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGCPKCDE_00289 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HGCPKCDE_00290 1.1e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HGCPKCDE_00291 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HGCPKCDE_00292 4.8e-51 yerC S protein conserved in bacteria
HGCPKCDE_00293 1.1e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
HGCPKCDE_00294 0.0 yerA 3.5.4.2 F adenine deaminase
HGCPKCDE_00295 2.7e-27 S Protein of unknown function (DUF2892)
HGCPKCDE_00296 2.8e-230 yjeH E Amino acid permease
HGCPKCDE_00297 1.1e-71 K helix_turn_helix ASNC type
HGCPKCDE_00298 1e-232 purD 6.3.4.13 F Belongs to the GARS family
HGCPKCDE_00299 3.9e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HGCPKCDE_00300 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HGCPKCDE_00301 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HGCPKCDE_00302 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HGCPKCDE_00303 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGCPKCDE_00304 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGCPKCDE_00305 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGCPKCDE_00306 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HGCPKCDE_00307 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HGCPKCDE_00308 2.2e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HGCPKCDE_00309 2.8e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HGCPKCDE_00310 8e-28 yebG S NETI protein
HGCPKCDE_00311 8.9e-93 yebE S UPF0316 protein
HGCPKCDE_00313 2.3e-118 yebC M Membrane
HGCPKCDE_00314 5.1e-211 pbuG S permease
HGCPKCDE_00315 5.8e-248 S Domain of unknown function (DUF4179)
HGCPKCDE_00316 1.9e-87 K Belongs to the sigma-70 factor family. ECF subfamily
HGCPKCDE_00317 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HGCPKCDE_00318 0.0 yebA E COG1305 Transglutaminase-like enzymes
HGCPKCDE_00319 1.5e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HGCPKCDE_00320 1.6e-174 yeaC S COG0714 MoxR-like ATPases
HGCPKCDE_00321 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGCPKCDE_00322 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HGCPKCDE_00323 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HGCPKCDE_00324 9.8e-175 yeaA S Protein of unknown function (DUF4003)
HGCPKCDE_00325 2.6e-157 ydjP I Alpha/beta hydrolase family
HGCPKCDE_00326 1.4e-34 ydjO S Cold-inducible protein YdjO
HGCPKCDE_00328 1.8e-155 ydjN U Involved in the tonB-independent uptake of proteins
HGCPKCDE_00329 4.5e-64 ydjM M Lytic transglycolase
HGCPKCDE_00330 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HGCPKCDE_00331 3.9e-257 iolT EGP Major facilitator Superfamily
HGCPKCDE_00332 3.3e-194 S Ion transport 2 domain protein
HGCPKCDE_00333 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
HGCPKCDE_00334 3.4e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HGCPKCDE_00335 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGCPKCDE_00336 1.3e-112 pspA KT Phage shock protein A
HGCPKCDE_00337 7.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HGCPKCDE_00338 6.7e-254 gutA G MFS/sugar transport protein
HGCPKCDE_00339 8.5e-201 gutB 1.1.1.14 E Dehydrogenase
HGCPKCDE_00340 0.0 K NB-ARC domain
HGCPKCDE_00341 6.8e-152 ydjC S Abhydrolase domain containing 18
HGCPKCDE_00342 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HGCPKCDE_00343 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HGCPKCDE_00344 7.9e-129 ydiL S CAAX protease self-immunity
HGCPKCDE_00345 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HGCPKCDE_00346 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HGCPKCDE_00347 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HGCPKCDE_00348 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HGCPKCDE_00349 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HGCPKCDE_00350 0.0 ydiF S ABC transporter
HGCPKCDE_00351 3.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HGCPKCDE_00352 6.2e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HGCPKCDE_00353 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HGCPKCDE_00354 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HGCPKCDE_00355 9e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HGCPKCDE_00357 7.8e-08
HGCPKCDE_00358 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HGCPKCDE_00359 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGCPKCDE_00360 4.1e-30 yazB K transcriptional
HGCPKCDE_00361 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HGCPKCDE_00362 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGCPKCDE_00363 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HGCPKCDE_00364 1.3e-165 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HGCPKCDE_00365 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HGCPKCDE_00366 1.7e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGCPKCDE_00367 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HGCPKCDE_00368 1.3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HGCPKCDE_00369 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HGCPKCDE_00370 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HGCPKCDE_00371 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGCPKCDE_00372 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HGCPKCDE_00373 3.8e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HGCPKCDE_00374 7.4e-186 KLT serine threonine protein kinase
HGCPKCDE_00375 2.9e-123 yabS S protein containing a von Willebrand factor type A (vWA) domain
HGCPKCDE_00376 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HGCPKCDE_00379 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HGCPKCDE_00380 1.1e-44 divIC D Septum formation initiator
HGCPKCDE_00381 3.9e-108 yabQ S spore cortex biosynthesis protein
HGCPKCDE_00382 1.5e-49 yabP S Sporulation protein YabP
HGCPKCDE_00383 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HGCPKCDE_00384 1.5e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HGCPKCDE_00385 1.7e-285 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGCPKCDE_00386 1.5e-92 spoVT K stage V sporulation protein
HGCPKCDE_00387 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HGCPKCDE_00388 2.4e-39 yabK S Peptide ABC transporter permease
HGCPKCDE_00389 1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HGCPKCDE_00390 9.6e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HGCPKCDE_00391 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGCPKCDE_00392 5.6e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGCPKCDE_00393 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HGCPKCDE_00394 5.6e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HGCPKCDE_00395 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HGCPKCDE_00396 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HGCPKCDE_00397 7.8e-39 veg S protein conserved in bacteria
HGCPKCDE_00398 1.8e-135 yabG S peptidase
HGCPKCDE_00399 2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HGCPKCDE_00400 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HGCPKCDE_00401 4.3e-194 rpfB GH23 T protein conserved in bacteria
HGCPKCDE_00402 4.5e-143 tatD L hydrolase, TatD
HGCPKCDE_00403 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGCPKCDE_00404 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HGCPKCDE_00405 2.3e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HGCPKCDE_00406 1.5e-49 yazA L endonuclease containing a URI domain
HGCPKCDE_00407 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HGCPKCDE_00408 4.8e-31 yabA L Involved in initiation control of chromosome replication
HGCPKCDE_00409 6.1e-146 yaaT S stage 0 sporulation protein
HGCPKCDE_00410 2.2e-182 holB 2.7.7.7 L DNA polymerase III
HGCPKCDE_00411 1.5e-71 yaaR S protein conserved in bacteria
HGCPKCDE_00412 2.2e-54 yaaQ S protein conserved in bacteria
HGCPKCDE_00413 5.8e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGCPKCDE_00414 4.3e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HGCPKCDE_00415 2.9e-202 yaaN P Belongs to the TelA family
HGCPKCDE_00416 1.8e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HGCPKCDE_00417 2.9e-30 csfB S Inhibitor of sigma-G Gin
HGCPKCDE_00418 1.8e-35 bofA S Sigma-K factor-processing regulatory protein BofA
HGCPKCDE_00419 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HGCPKCDE_00420 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HGCPKCDE_00421 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HGCPKCDE_00422 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGCPKCDE_00423 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HGCPKCDE_00424 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
HGCPKCDE_00425 2.4e-213 yaaH M Glycoside Hydrolase Family
HGCPKCDE_00426 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HGCPKCDE_00427 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HGCPKCDE_00428 1.3e-09
HGCPKCDE_00429 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HGCPKCDE_00430 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HGCPKCDE_00431 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HGCPKCDE_00432 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HGCPKCDE_00433 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HGCPKCDE_00434 8.7e-181 yaaC S YaaC-like Protein
HGCPKCDE_00435 1.3e-63 hxlR K transcriptional
HGCPKCDE_00436 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HGCPKCDE_00437 1.8e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HGCPKCDE_00438 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
HGCPKCDE_00439 5.6e-69 nucA M Deoxyribonuclease NucA/NucB
HGCPKCDE_00440 8.5e-69 nin S Competence protein J (ComJ)
HGCPKCDE_00441 9.5e-285 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGCPKCDE_00442 7.8e-52 yckD S Protein of unknown function (DUF2680)
HGCPKCDE_00443 3.8e-73 yckC S membrane
HGCPKCDE_00446 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HGCPKCDE_00447 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
HGCPKCDE_00448 1e-226 yciC S GTPases (G3E family)
HGCPKCDE_00449 1e-107 yciB M ErfK YbiS YcfS YnhG
HGCPKCDE_00450 2.4e-167 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HGCPKCDE_00451 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
HGCPKCDE_00452 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HGCPKCDE_00453 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGCPKCDE_00454 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HGCPKCDE_00455 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HGCPKCDE_00456 3e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HGCPKCDE_00457 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HGCPKCDE_00458 1.6e-157 I alpha/beta hydrolase fold
HGCPKCDE_00459 9.1e-140 ycgR S permeases
HGCPKCDE_00460 2.7e-144 ycgQ S membrane
HGCPKCDE_00461 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HGCPKCDE_00462 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGCPKCDE_00463 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HGCPKCDE_00464 5.1e-170 ycgM E Proline dehydrogenase
HGCPKCDE_00465 2.9e-145 ycgL S Predicted nucleotidyltransferase
HGCPKCDE_00466 1.4e-181 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HGCPKCDE_00467 1.2e-177 oxyR3 K LysR substrate binding domain
HGCPKCDE_00468 3.4e-143 yafE Q ubiE/COQ5 methyltransferase family
HGCPKCDE_00469 1.9e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HGCPKCDE_00471 5.8e-106 tmrB S AAA domain
HGCPKCDE_00472 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HGCPKCDE_00473 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HGCPKCDE_00474 1.4e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HGCPKCDE_00475 4.6e-148 yqcI S YqcI/YcgG family
HGCPKCDE_00476 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HGCPKCDE_00477 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HGCPKCDE_00478 6.2e-269 mdr EGP Major facilitator Superfamily
HGCPKCDE_00479 5.2e-290 lctP C L-lactate permease
HGCPKCDE_00480 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGCPKCDE_00481 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HGCPKCDE_00482 4.5e-80 ycgB
HGCPKCDE_00483 5.6e-256 ycgA S Membrane
HGCPKCDE_00484 1.4e-217 amhX S amidohydrolase
HGCPKCDE_00485 1.5e-163 opuAC E glycine betaine
HGCPKCDE_00486 8.5e-127 opuAB P glycine betaine
HGCPKCDE_00487 5.1e-229 proV 3.6.3.32 E glycine betaine
HGCPKCDE_00488 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HGCPKCDE_00489 5.7e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
HGCPKCDE_00490 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
HGCPKCDE_00491 2e-192 yceH P Belongs to the TelA family
HGCPKCDE_00492 0.0 yceG S Putative component of 'biosynthetic module'
HGCPKCDE_00493 1.4e-136 terC P Protein of unknown function (DUF475)
HGCPKCDE_00494 3.9e-107 yceE T proteins involved in stress response, homologs of TerZ and
HGCPKCDE_00495 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HGCPKCDE_00496 1.9e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HGCPKCDE_00497 3.4e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCPKCDE_00498 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HGCPKCDE_00499 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HGCPKCDE_00500 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
HGCPKCDE_00501 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HGCPKCDE_00502 6.8e-139 IQ Enoyl-(Acyl carrier protein) reductase
HGCPKCDE_00503 3.6e-173 S response regulator aspartate phosphatase
HGCPKCDE_00504 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
HGCPKCDE_00505 8.2e-258 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HGCPKCDE_00506 1.1e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HGCPKCDE_00507 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HGCPKCDE_00508 1.7e-173 yccK C Aldo keto reductase
HGCPKCDE_00509 2.2e-202 natB CP ABC-2 family transporter protein
HGCPKCDE_00510 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HGCPKCDE_00511 1.2e-126 lytR_2 T LytTr DNA-binding domain
HGCPKCDE_00512 3.6e-158 2.7.13.3 T GHKL domain
HGCPKCDE_00513 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
HGCPKCDE_00514 7.1e-57 S RDD family
HGCPKCDE_00515 2.1e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HGCPKCDE_00516 4.5e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HGCPKCDE_00517 1.3e-99 yxaF K Transcriptional regulator
HGCPKCDE_00518 5.8e-229 lmrB EGP the major facilitator superfamily
HGCPKCDE_00519 7.3e-203 ycbU E Selenocysteine lyase
HGCPKCDE_00520 4.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HGCPKCDE_00521 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HGCPKCDE_00522 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HGCPKCDE_00523 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HGCPKCDE_00524 5.6e-135 ycbR T vWA found in TerF C terminus
HGCPKCDE_00525 1.3e-78 sleB 3.5.1.28 M Cell wall
HGCPKCDE_00526 1.6e-51 ycbP S Protein of unknown function (DUF2512)
HGCPKCDE_00527 5.1e-114 S ABC-2 family transporter protein
HGCPKCDE_00528 6.3e-168 ycbN V ABC transporter, ATP-binding protein
HGCPKCDE_00529 1.9e-167 T PhoQ Sensor
HGCPKCDE_00530 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCPKCDE_00531 3.6e-171 eamA1 EG spore germination
HGCPKCDE_00532 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HGCPKCDE_00533 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
HGCPKCDE_00534 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
HGCPKCDE_00535 1.5e-124 ycbG K FCD
HGCPKCDE_00536 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HGCPKCDE_00537 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HGCPKCDE_00538 1.7e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGCPKCDE_00539 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HGCPKCDE_00540 9e-170 glnL T Regulator
HGCPKCDE_00541 8.8e-227 phoQ 2.7.13.3 T Histidine kinase
HGCPKCDE_00542 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
HGCPKCDE_00543 5.6e-256 agcS E Sodium alanine symporter
HGCPKCDE_00545 9.6e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HGCPKCDE_00546 2.6e-261 mmuP E amino acid
HGCPKCDE_00547 1e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HGCPKCDE_00549 4.9e-128 K UTRA
HGCPKCDE_00550 4.4e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGCPKCDE_00551 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCPKCDE_00552 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGCPKCDE_00553 8.6e-192 yceA S Belongs to the UPF0176 family
HGCPKCDE_00554 4.6e-45 ybfN
HGCPKCDE_00555 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HGCPKCDE_00556 2.7e-85 ybfM S SNARE associated Golgi protein
HGCPKCDE_00557 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGCPKCDE_00558 2.5e-169 S Alpha/beta hydrolase family
HGCPKCDE_00560 1.5e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HGCPKCDE_00561 1.2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HGCPKCDE_00562 2.3e-145 msmR K AraC-like ligand binding domain
HGCPKCDE_00563 3.3e-161 ybfH EG EamA-like transporter family
HGCPKCDE_00564 0.0 ybfG M Domain of unknown function (DUF1906)
HGCPKCDE_00566 6.7e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
HGCPKCDE_00567 9.7e-153 ybfA 3.4.15.5 K FR47-like protein
HGCPKCDE_00568 1.5e-34 S Protein of unknown function (DUF2651)
HGCPKCDE_00569 7.3e-258 glpT G -transporter
HGCPKCDE_00570 8.2e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HGCPKCDE_00571 2.3e-290 ybeC E amino acid
HGCPKCDE_00572 8.3e-41 ybyB
HGCPKCDE_00573 2.3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HGCPKCDE_00574 1.8e-150 ybxI 3.5.2.6 V beta-lactamase
HGCPKCDE_00575 4.9e-30 ybxH S Family of unknown function (DUF5370)
HGCPKCDE_00576 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
HGCPKCDE_00577 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HGCPKCDE_00578 4.7e-216 ybdO S Domain of unknown function (DUF4885)
HGCPKCDE_00579 1.7e-151 ybdN
HGCPKCDE_00580 2e-138 KLT Protein tyrosine kinase
HGCPKCDE_00582 2e-172 T His Kinase A (phospho-acceptor) domain
HGCPKCDE_00583 3.8e-122 T Transcriptional regulatory protein, C terminal
HGCPKCDE_00584 5.3e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HGCPKCDE_00585 3.3e-56
HGCPKCDE_00586 2.9e-202 ybcL EGP Major facilitator Superfamily
HGCPKCDE_00587 5.1e-50 ybzH K Helix-turn-helix domain
HGCPKCDE_00588 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HGCPKCDE_00589 3.9e-47
HGCPKCDE_00590 1.3e-93 can 4.2.1.1 P carbonic anhydrase
HGCPKCDE_00591 0.0 ybcC S Belongs to the UPF0753 family
HGCPKCDE_00592 5.3e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HGCPKCDE_00593 9.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HGCPKCDE_00594 9.8e-120 adaA 3.2.2.21 K Transcriptional regulator
HGCPKCDE_00595 1.8e-170 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HGCPKCDE_00596 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HGCPKCDE_00597 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGCPKCDE_00598 1.5e-224 ybbR S protein conserved in bacteria
HGCPKCDE_00599 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGCPKCDE_00600 2.7e-101 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HGCPKCDE_00601 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HGCPKCDE_00607 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HGCPKCDE_00608 1.9e-86 ybbJ J acetyltransferase
HGCPKCDE_00609 6.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HGCPKCDE_00610 1.4e-150 ybbH K transcriptional
HGCPKCDE_00611 1.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCPKCDE_00612 3.1e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HGCPKCDE_00613 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HGCPKCDE_00614 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
HGCPKCDE_00615 2.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HGCPKCDE_00616 1.4e-165 feuA P Iron-uptake system-binding protein
HGCPKCDE_00617 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCPKCDE_00618 5.6e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCPKCDE_00619 4.7e-137 ybbA S Putative esterase
HGCPKCDE_00620 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
HGCPKCDE_00622 1.5e-245 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HGCPKCDE_00623 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCPKCDE_00624 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCPKCDE_00625 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HGCPKCDE_00626 5.7e-140 srfAD Q thioesterase
HGCPKCDE_00627 2e-225 EGP Major Facilitator Superfamily
HGCPKCDE_00628 6.9e-85 S YcxB-like protein
HGCPKCDE_00629 2.9e-160 ycxC EG EamA-like transporter family
HGCPKCDE_00630 3.7e-254 ycxD K GntR family transcriptional regulator
HGCPKCDE_00631 3.3e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HGCPKCDE_00632 9.7e-115 yczE S membrane
HGCPKCDE_00633 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HGCPKCDE_00634 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HGCPKCDE_00635 6.4e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HGCPKCDE_00636 1.2e-160 bsdA K LysR substrate binding domain
HGCPKCDE_00637 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HGCPKCDE_00638 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HGCPKCDE_00639 4e-39 bsdD 4.1.1.61 S response to toxic substance
HGCPKCDE_00640 1.6e-79 yclD
HGCPKCDE_00641 6.2e-154 yclE 3.4.11.5 S Alpha beta hydrolase
HGCPKCDE_00642 6.2e-266 dtpT E amino acid peptide transporter
HGCPKCDE_00643 1.7e-307 yclG M Pectate lyase superfamily protein
HGCPKCDE_00645 4.4e-281 gerKA EG Spore germination protein
HGCPKCDE_00646 8.2e-232 gerKC S spore germination
HGCPKCDE_00647 1.7e-199 gerKB F Spore germination protein
HGCPKCDE_00648 9.5e-121 yclH P ABC transporter
HGCPKCDE_00649 1.3e-202 yclI V ABC transporter (permease) YclI
HGCPKCDE_00650 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCPKCDE_00651 6.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HGCPKCDE_00652 5.8e-78 S aspartate phosphatase
HGCPKCDE_00656 1.8e-251 lysC 2.7.2.4 E Belongs to the aspartokinase family
HGCPKCDE_00657 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCPKCDE_00658 1.8e-162 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCPKCDE_00659 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HGCPKCDE_00660 1.8e-165 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HGCPKCDE_00661 4.1e-251 ycnB EGP Major facilitator Superfamily
HGCPKCDE_00662 5.5e-153 ycnC K Transcriptional regulator
HGCPKCDE_00663 2.8e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HGCPKCDE_00664 1.6e-45 ycnE S Monooxygenase
HGCPKCDE_00665 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HGCPKCDE_00666 4.3e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCPKCDE_00667 3.7e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGCPKCDE_00668 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGCPKCDE_00669 1.8e-148 glcU U Glucose uptake
HGCPKCDE_00670 1.7e-145 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCPKCDE_00671 7.1e-99 ycnI S protein conserved in bacteria
HGCPKCDE_00672 2.1e-307 ycnJ P protein, homolog of Cu resistance protein CopC
HGCPKCDE_00673 2.8e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HGCPKCDE_00674 3.4e-53
HGCPKCDE_00675 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HGCPKCDE_00676 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HGCPKCDE_00677 1.8e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HGCPKCDE_00678 7.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HGCPKCDE_00680 1.7e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HGCPKCDE_00681 1.4e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HGCPKCDE_00682 1.2e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HGCPKCDE_00684 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HGCPKCDE_00685 2.3e-139 ycsF S Belongs to the UPF0271 (lamB) family
HGCPKCDE_00686 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HGCPKCDE_00687 3.4e-129 ycsI S Belongs to the D-glutamate cyclase family
HGCPKCDE_00688 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HGCPKCDE_00689 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HGCPKCDE_00690 2.7e-132 kipR K Transcriptional regulator
HGCPKCDE_00691 3.8e-119 ycsK E anatomical structure formation involved in morphogenesis
HGCPKCDE_00693 9.2e-49 yczJ S biosynthesis
HGCPKCDE_00694 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HGCPKCDE_00695 8.3e-173 ydhF S Oxidoreductase
HGCPKCDE_00696 0.0 mtlR K transcriptional regulator, MtlR
HGCPKCDE_00697 1.8e-292 ydaB IQ acyl-CoA ligase
HGCPKCDE_00698 9e-99 ydaC Q Methyltransferase domain
HGCPKCDE_00699 1.2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCPKCDE_00700 5.1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HGCPKCDE_00701 7.3e-103 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGCPKCDE_00702 6.8e-77 ydaG 1.4.3.5 S general stress protein
HGCPKCDE_00703 9.2e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HGCPKCDE_00704 3.6e-45 ydzA EGP Major facilitator Superfamily
HGCPKCDE_00705 2.5e-74 lrpC K Transcriptional regulator
HGCPKCDE_00706 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGCPKCDE_00707 2.2e-204 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HGCPKCDE_00708 4.2e-150 ydaK T Diguanylate cyclase, GGDEF domain
HGCPKCDE_00709 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HGCPKCDE_00710 4.5e-233 ydaM M Glycosyl transferase family group 2
HGCPKCDE_00711 0.0 ydaN S Bacterial cellulose synthase subunit
HGCPKCDE_00712 0.0 ydaO E amino acid
HGCPKCDE_00713 1.6e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HGCPKCDE_00714 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HGCPKCDE_00716 1.8e-27
HGCPKCDE_00717 1.8e-72 sdpB S Protein conserved in bacteria
HGCPKCDE_00719 9.4e-40
HGCPKCDE_00720 1.7e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HGCPKCDE_00722 1.6e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HGCPKCDE_00723 2.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HGCPKCDE_00725 8.9e-59 ydbB G Cupin domain
HGCPKCDE_00726 9e-62 ydbC S Domain of unknown function (DUF4937
HGCPKCDE_00727 2.3e-153 ydbD P Catalase
HGCPKCDE_00728 6.7e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HGCPKCDE_00729 4e-295 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HGCPKCDE_00730 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
HGCPKCDE_00731 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGCPKCDE_00732 4.4e-181 ydbI S AI-2E family transporter
HGCPKCDE_00734 4.7e-171 ydbJ V ABC transporter, ATP-binding protein
HGCPKCDE_00735 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HGCPKCDE_00736 2.7e-52 ydbL
HGCPKCDE_00737 7.5e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HGCPKCDE_00738 1.1e-18 S Fur-regulated basic protein B
HGCPKCDE_00739 2.2e-07 S Fur-regulated basic protein A
HGCPKCDE_00740 7.3e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGCPKCDE_00741 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HGCPKCDE_00742 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HGCPKCDE_00743 7.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HGCPKCDE_00744 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HGCPKCDE_00745 2.1e-82 ydbS S Bacterial PH domain
HGCPKCDE_00746 3.9e-260 ydbT S Membrane
HGCPKCDE_00747 9e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HGCPKCDE_00748 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HGCPKCDE_00749 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HGCPKCDE_00750 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGCPKCDE_00751 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HGCPKCDE_00752 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HGCPKCDE_00753 1.3e-143 rsbR T Positive regulator of sigma-B
HGCPKCDE_00754 5.2e-57 rsbS T antagonist
HGCPKCDE_00755 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HGCPKCDE_00756 7.1e-189 rsbU 3.1.3.3 KT phosphatase
HGCPKCDE_00757 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HGCPKCDE_00758 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HGCPKCDE_00759 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCPKCDE_00760 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HGCPKCDE_00761 0.0 yhgF K COG2183 Transcriptional accessory protein
HGCPKCDE_00762 8.9e-83 ydcK S Belongs to the SprT family
HGCPKCDE_00771 1.5e-14 S SMI1-KNR4 cell-wall
HGCPKCDE_00772 8.5e-45
HGCPKCDE_00773 2.1e-140 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HGCPKCDE_00774 3.4e-33 K Helix-turn-helix XRE-family like proteins
HGCPKCDE_00775 4.6e-42
HGCPKCDE_00776 2.7e-191 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HGCPKCDE_00777 8.7e-30 cspL K Cold shock
HGCPKCDE_00778 6.1e-79 carD K Transcription factor
HGCPKCDE_00779 1.2e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HGCPKCDE_00780 7.6e-163 rhaS5 K AraC-like ligand binding domain
HGCPKCDE_00781 4.9e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HGCPKCDE_00782 6.9e-164 ydeE K AraC family transcriptional regulator
HGCPKCDE_00783 9.6e-261 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCPKCDE_00784 3.9e-216 ydeG EGP Major facilitator superfamily
HGCPKCDE_00785 2.3e-44 ydeH
HGCPKCDE_00786 6.4e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HGCPKCDE_00787 7.7e-107
HGCPKCDE_00788 7e-14 ptsH G PTS HPr component phosphorylation site
HGCPKCDE_00789 8.8e-85 K Transcriptional regulator C-terminal region
HGCPKCDE_00790 2.9e-151 ydeK EG -transporter
HGCPKCDE_00791 2.2e-273 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCPKCDE_00792 4.2e-74 maoC I N-terminal half of MaoC dehydratase
HGCPKCDE_00793 9.5e-106 ydeN S Serine hydrolase
HGCPKCDE_00794 1e-56 K HxlR-like helix-turn-helix
HGCPKCDE_00795 1.6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HGCPKCDE_00796 4.8e-69 ydeP K Transcriptional regulator
HGCPKCDE_00797 3.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
HGCPKCDE_00798 3.3e-193 ydeR EGP Major facilitator Superfamily
HGCPKCDE_00799 2.1e-103 ydeS K Transcriptional regulator
HGCPKCDE_00800 6.3e-57 arsR K transcriptional
HGCPKCDE_00801 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HGCPKCDE_00802 2.1e-148 ydfB J GNAT acetyltransferase
HGCPKCDE_00803 4.8e-160 ydfC EG EamA-like transporter family
HGCPKCDE_00804 1e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCPKCDE_00805 1.9e-115 ydfE S Flavin reductase like domain
HGCPKCDE_00806 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HGCPKCDE_00807 3.8e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HGCPKCDE_00809 1.8e-175 ydfH 2.7.13.3 T Histidine kinase
HGCPKCDE_00810 9.3e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCPKCDE_00811 0.0 ydfJ S drug exporters of the RND superfamily
HGCPKCDE_00812 4e-175 S Alpha/beta hydrolase family
HGCPKCDE_00813 9.3e-116 S Protein of unknown function (DUF554)
HGCPKCDE_00814 3.2e-147 K Bacterial transcription activator, effector binding domain
HGCPKCDE_00815 2e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGCPKCDE_00816 1.2e-109 ydfN C nitroreductase
HGCPKCDE_00817 2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HGCPKCDE_00818 8.8e-63 mhqP S DoxX
HGCPKCDE_00819 5.3e-56 traF CO Thioredoxin
HGCPKCDE_00820 9.3e-15 ydgA S Spore germination protein gerPA/gerPF
HGCPKCDE_00821 6.3e-29
HGCPKCDE_00823 4.4e-118 ydfR S Protein of unknown function (DUF421)
HGCPKCDE_00824 1.2e-121 ydfS S Protein of unknown function (DUF421)
HGCPKCDE_00825 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
HGCPKCDE_00826 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
HGCPKCDE_00827 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HGCPKCDE_00828 1.7e-97 K Bacterial regulatory proteins, tetR family
HGCPKCDE_00829 4.8e-52 S DoxX-like family
HGCPKCDE_00830 1.7e-84 yycN 2.3.1.128 K Acetyltransferase
HGCPKCDE_00831 2.1e-30 FG HIT domain
HGCPKCDE_00832 5.1e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HGCPKCDE_00833 2e-119 purR K helix_turn _helix lactose operon repressor
HGCPKCDE_00834 1.7e-190 csbC EGP Major facilitator Superfamily
HGCPKCDE_00835 7.5e-104 G Xylose isomerase-like TIM barrel
HGCPKCDE_00836 1.8e-303 expZ S ABC transporter
HGCPKCDE_00837 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HGCPKCDE_00838 3e-90 dinB S DinB family
HGCPKCDE_00839 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
HGCPKCDE_00840 0.0 ydgH S drug exporters of the RND superfamily
HGCPKCDE_00841 1e-113 drgA C nitroreductase
HGCPKCDE_00842 2.4e-69 ydgJ K Winged helix DNA-binding domain
HGCPKCDE_00843 8.2e-208 tcaB EGP Major facilitator Superfamily
HGCPKCDE_00844 1.2e-121 ydhB S membrane transporter protein
HGCPKCDE_00845 1.6e-120 ydhC K FCD
HGCPKCDE_00846 1.1e-242 ydhD M Glycosyl hydrolase
HGCPKCDE_00847 1.7e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HGCPKCDE_00848 4.6e-126
HGCPKCDE_00849 2.6e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HGCPKCDE_00850 8.7e-68 frataxin S Domain of unknown function (DU1801)
HGCPKCDE_00852 1.9e-83 K Acetyltransferase (GNAT) domain
HGCPKCDE_00853 5.8e-180 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HGCPKCDE_00854 9.5e-98 ydhK M Protein of unknown function (DUF1541)
HGCPKCDE_00855 1.3e-199 pbuE EGP Major facilitator Superfamily
HGCPKCDE_00856 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HGCPKCDE_00857 6.6e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HGCPKCDE_00858 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGCPKCDE_00859 3.6e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGCPKCDE_00860 1.1e-132 ydhQ K UTRA
HGCPKCDE_00861 3e-170 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HGCPKCDE_00862 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HGCPKCDE_00863 2.9e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HGCPKCDE_00864 2.3e-156 ydhU P Catalase
HGCPKCDE_00867 2e-68 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCPKCDE_00868 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCPKCDE_00869 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCPKCDE_00870 9.8e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HGCPKCDE_00871 9.6e-191 yoxA 5.1.3.3 G Aldose 1-epimerase
HGCPKCDE_00872 3.3e-245 yoeA V MATE efflux family protein
HGCPKCDE_00873 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HGCPKCDE_00875 5e-96 L Integrase
HGCPKCDE_00876 5.1e-34 yoeD G Helix-turn-helix domain
HGCPKCDE_00877 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HGCPKCDE_00878 3e-156 gltR1 K Transcriptional regulator
HGCPKCDE_00879 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HGCPKCDE_00880 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HGCPKCDE_00881 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HGCPKCDE_00882 7.8e-155 gltC K Transcriptional regulator
HGCPKCDE_00883 2.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGCPKCDE_00884 7.3e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGCPKCDE_00885 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HGCPKCDE_00886 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCPKCDE_00887 7e-39 yoxC S Bacterial protein of unknown function (DUF948)
HGCPKCDE_00888 1.3e-131 yoxB
HGCPKCDE_00889 8.9e-90 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGCPKCDE_00890 1.7e-241 S Arylsulfotransferase (ASST)
HGCPKCDE_00891 1.9e-126 3.1.1.3 I Lipase (class 3)
HGCPKCDE_00892 4e-234 yoaB EGP Major facilitator Superfamily
HGCPKCDE_00893 9.1e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HGCPKCDE_00894 1.5e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGCPKCDE_00895 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGCPKCDE_00896 1.1e-33 yoaF
HGCPKCDE_00899 2.6e-13
HGCPKCDE_00900 1.3e-37 S Protein of unknown function (DUF4025)
HGCPKCDE_00901 2.6e-180 mcpU NT methyl-accepting chemotaxis protein
HGCPKCDE_00902 6.2e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HGCPKCDE_00903 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HGCPKCDE_00904 2.6e-110 yoaK S Membrane
HGCPKCDE_00905 1.2e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HGCPKCDE_00906 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
HGCPKCDE_00909 8.9e-77 oxdC 4.1.1.2 G Oxalate decarboxylase
HGCPKCDE_00910 6.9e-144 oxdC 4.1.1.2 G Oxalate decarboxylase
HGCPKCDE_00912 3.4e-143 yoaP 3.1.3.18 K YoaP-like
HGCPKCDE_00913 2.7e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
HGCPKCDE_00915 6.6e-87
HGCPKCDE_00916 7.1e-172 yoaR V vancomycin resistance protein
HGCPKCDE_00917 7.3e-75 yoaS S Protein of unknown function (DUF2975)
HGCPKCDE_00918 4.4e-30 yozG K Transcriptional regulator
HGCPKCDE_00919 7.4e-149 yoaT S Protein of unknown function (DUF817)
HGCPKCDE_00920 5.6e-158 yoaU K LysR substrate binding domain
HGCPKCDE_00921 3.7e-157 yijE EG EamA-like transporter family
HGCPKCDE_00922 3.1e-77 yoaW
HGCPKCDE_00923 9.8e-112 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HGCPKCDE_00924 9.1e-167 bla 3.5.2.6 V beta-lactamase
HGCPKCDE_00927 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HGCPKCDE_00928 6.9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HGCPKCDE_00929 1.3e-35 S TM2 domain
HGCPKCDE_00930 2.4e-56 K Helix-turn-helix
HGCPKCDE_00933 9.5e-50 FG Scavenger mRNA decapping enzyme C-term binding
HGCPKCDE_00938 4.6e-11 ywlA S Uncharacterised protein family (UPF0715)
HGCPKCDE_00942 9.1e-54 S Tetratricopeptide repeat
HGCPKCDE_00943 5.2e-61 J tRNA cytidylyltransferase activity
HGCPKCDE_00951 2.4e-206 S aspartate phosphatase
HGCPKCDE_00953 5.6e-158 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGCPKCDE_00954 4.2e-33 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGCPKCDE_00956 1.6e-17
HGCPKCDE_00958 1.5e-19
HGCPKCDE_00959 6.5e-10 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HGCPKCDE_00960 5.1e-91 yokH G SMI1 / KNR4 family
HGCPKCDE_00961 1.9e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HGCPKCDE_00962 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HGCPKCDE_00963 7.9e-134 yobQ K helix_turn_helix, arabinose operon control protein
HGCPKCDE_00964 9.1e-141 yobR 2.3.1.1 J FR47-like protein
HGCPKCDE_00965 1.3e-97 yobS K Transcriptional regulator
HGCPKCDE_00966 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HGCPKCDE_00967 5.4e-86 yobU K Bacterial transcription activator, effector binding domain
HGCPKCDE_00968 9.3e-175 yobV K WYL domain
HGCPKCDE_00969 7.4e-92 yobW
HGCPKCDE_00970 1e-51 czrA K transcriptional
HGCPKCDE_00971 2.4e-108 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HGCPKCDE_00972 1.5e-92 yozB S membrane
HGCPKCDE_00973 7.3e-141
HGCPKCDE_00974 1.5e-91 yocC
HGCPKCDE_00975 1.3e-182 yocD 3.4.17.13 V peptidase S66
HGCPKCDE_00976 3.4e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HGCPKCDE_00977 7.1e-198 desK 2.7.13.3 T Histidine kinase
HGCPKCDE_00978 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCPKCDE_00979 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HGCPKCDE_00980 0.0 recQ 3.6.4.12 L DNA helicase
HGCPKCDE_00981 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HGCPKCDE_00982 3.3e-83 dksA T general stress protein
HGCPKCDE_00983 1.4e-53 yocL
HGCPKCDE_00984 6.2e-32
HGCPKCDE_00985 1.1e-86 yocM O Belongs to the small heat shock protein (HSP20) family
HGCPKCDE_00986 1.1e-40 yozN
HGCPKCDE_00987 1.9e-36 yocN
HGCPKCDE_00988 4.2e-56 yozO S Bacterial PH domain
HGCPKCDE_00989 2.7e-31 yozC
HGCPKCDE_00990 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HGCPKCDE_00991 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HGCPKCDE_00992 6e-165 sodA 1.15.1.1 P Superoxide dismutase
HGCPKCDE_00993 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HGCPKCDE_00994 4.3e-167 yocS S -transporter
HGCPKCDE_00995 2e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HGCPKCDE_00996 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HGCPKCDE_00997 0.0 yojO P Von Willebrand factor
HGCPKCDE_00998 2.1e-160 yojN S ATPase family associated with various cellular activities (AAA)
HGCPKCDE_00999 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HGCPKCDE_01000 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HGCPKCDE_01001 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HGCPKCDE_01002 7.6e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGCPKCDE_01004 1.4e-243 norM V Multidrug efflux pump
HGCPKCDE_01005 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGCPKCDE_01006 2.1e-125 yojG S deacetylase
HGCPKCDE_01007 2.2e-60 yojF S Protein of unknown function (DUF1806)
HGCPKCDE_01008 1.5e-43
HGCPKCDE_01009 5.6e-161 rarD S -transporter
HGCPKCDE_01010 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
HGCPKCDE_01011 2.6e-09
HGCPKCDE_01012 2.1e-181 gntP EG COG2610 H gluconate symporter and related permeases
HGCPKCDE_01013 5e-16 gntP EG COG2610 H gluconate symporter and related permeases
HGCPKCDE_01014 8e-64 yodA S tautomerase
HGCPKCDE_01015 4.4e-55 yodB K transcriptional
HGCPKCDE_01016 1.4e-107 yodC C nitroreductase
HGCPKCDE_01017 1.2e-111 mhqD S Carboxylesterase
HGCPKCDE_01018 3.2e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
HGCPKCDE_01019 6.2e-28 S Protein of unknown function (DUF3311)
HGCPKCDE_01020 7.3e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGCPKCDE_01021 2.8e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HGCPKCDE_01022 5.4e-127 yodH Q Methyltransferase
HGCPKCDE_01023 1.5e-23 yodI
HGCPKCDE_01024 3.7e-135 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HGCPKCDE_01025 9.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HGCPKCDE_01026 5.3e-09
HGCPKCDE_01027 3.6e-54 yodL S YodL-like
HGCPKCDE_01028 1.6e-106 yodM 3.6.1.27 I Acid phosphatase homologues
HGCPKCDE_01029 6.3e-24 yozD S YozD-like protein
HGCPKCDE_01031 1.6e-123 yodN
HGCPKCDE_01032 1.4e-36 yozE S Belongs to the UPF0346 family
HGCPKCDE_01033 2.9e-47 yokU S YokU-like protein, putative antitoxin
HGCPKCDE_01034 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
HGCPKCDE_01035 7.9e-154 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HGCPKCDE_01036 3.5e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
HGCPKCDE_01037 8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HGCPKCDE_01038 5.5e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HGCPKCDE_01039 1.4e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGCPKCDE_01041 2.7e-143 yiiD K acetyltransferase
HGCPKCDE_01042 1.1e-255 cgeD M maturation of the outermost layer of the spore
HGCPKCDE_01043 3.5e-38 cgeC
HGCPKCDE_01044 1.2e-65 cgeA
HGCPKCDE_01045 1.3e-187 cgeB S Spore maturation protein
HGCPKCDE_01046 1e-207 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HGCPKCDE_01047 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
HGCPKCDE_01048 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HGCPKCDE_01049 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGCPKCDE_01050 1.6e-70 ypoP K transcriptional
HGCPKCDE_01051 1.7e-222 mepA V MATE efflux family protein
HGCPKCDE_01052 5.5e-29 ypmT S Uncharacterized ympT
HGCPKCDE_01053 1.1e-98 ypmS S protein conserved in bacteria
HGCPKCDE_01054 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HGCPKCDE_01055 3.5e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HGCPKCDE_01056 3.1e-40 ypmP S Protein of unknown function (DUF2535)
HGCPKCDE_01057 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HGCPKCDE_01058 1.6e-185 pspF K Transcriptional regulator
HGCPKCDE_01059 4.2e-110 hlyIII S protein, Hemolysin III
HGCPKCDE_01060 3.7e-111 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HGCPKCDE_01061 5.1e-95 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HGCPKCDE_01062 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGCPKCDE_01063 7.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HGCPKCDE_01064 7.8e-114 ypjP S YpjP-like protein
HGCPKCDE_01065 1.6e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HGCPKCDE_01066 1.5e-74 yphP S Belongs to the UPF0403 family
HGCPKCDE_01067 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HGCPKCDE_01068 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
HGCPKCDE_01069 9.3e-107 ypgQ S phosphohydrolase
HGCPKCDE_01070 5.2e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HGCPKCDE_01071 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HGCPKCDE_01073 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HGCPKCDE_01074 7.9e-31 cspD K Cold-shock protein
HGCPKCDE_01075 3.8e-16 degR
HGCPKCDE_01076 8.1e-31 S Protein of unknown function (DUF2564)
HGCPKCDE_01077 3e-29 ypeQ S Zinc-finger
HGCPKCDE_01078 1.8e-134 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HGCPKCDE_01079 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HGCPKCDE_01080 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
HGCPKCDE_01082 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HGCPKCDE_01083 2e-07
HGCPKCDE_01084 1e-38 ypbS S Protein of unknown function (DUF2533)
HGCPKCDE_01085 0.0 ypbR S Dynamin family
HGCPKCDE_01086 5.1e-87 ypbQ S protein conserved in bacteria
HGCPKCDE_01087 1.5e-205 bcsA Q Naringenin-chalcone synthase
HGCPKCDE_01088 1.6e-228 pbuX F xanthine
HGCPKCDE_01089 1.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HGCPKCDE_01090 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HGCPKCDE_01091 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HGCPKCDE_01092 2.7e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HGCPKCDE_01093 1.9e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HGCPKCDE_01094 1.5e-186 ptxS K transcriptional
HGCPKCDE_01095 1.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HGCPKCDE_01096 1.6e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCPKCDE_01097 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HGCPKCDE_01099 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HGCPKCDE_01100 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HGCPKCDE_01101 2.8e-91 ypsA S Belongs to the UPF0398 family
HGCPKCDE_01102 2.1e-235 yprB L RNase_H superfamily
HGCPKCDE_01103 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HGCPKCDE_01104 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HGCPKCDE_01105 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
HGCPKCDE_01106 1.2e-48 yppG S YppG-like protein
HGCPKCDE_01108 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
HGCPKCDE_01111 1.7e-187 yppC S Protein of unknown function (DUF2515)
HGCPKCDE_01112 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HGCPKCDE_01113 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HGCPKCDE_01114 4.7e-93 ypoC
HGCPKCDE_01115 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HGCPKCDE_01116 1.3e-128 dnaD L DNA replication protein DnaD
HGCPKCDE_01117 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HGCPKCDE_01118 7.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HGCPKCDE_01119 2.2e-79 ypmB S protein conserved in bacteria
HGCPKCDE_01120 1.9e-22 ypmA S Protein of unknown function (DUF4264)
HGCPKCDE_01121 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HGCPKCDE_01122 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HGCPKCDE_01123 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HGCPKCDE_01124 9.2e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HGCPKCDE_01125 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HGCPKCDE_01126 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HGCPKCDE_01127 1.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HGCPKCDE_01128 3.4e-129 bshB1 S proteins, LmbE homologs
HGCPKCDE_01129 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HGCPKCDE_01130 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HGCPKCDE_01131 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HGCPKCDE_01132 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HGCPKCDE_01133 6.1e-143 ypjB S sporulation protein
HGCPKCDE_01134 4.4e-98 ypjA S membrane
HGCPKCDE_01135 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HGCPKCDE_01136 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HGCPKCDE_01137 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HGCPKCDE_01138 1.6e-76 ypiF S Protein of unknown function (DUF2487)
HGCPKCDE_01139 1.1e-98 ypiB S Belongs to the UPF0302 family
HGCPKCDE_01140 9.1e-234 S COG0457 FOG TPR repeat
HGCPKCDE_01141 1.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HGCPKCDE_01142 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HGCPKCDE_01143 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HGCPKCDE_01144 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HGCPKCDE_01145 4.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HGCPKCDE_01146 3e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HGCPKCDE_01147 9.5e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HGCPKCDE_01148 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HGCPKCDE_01149 8.9e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGCPKCDE_01150 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HGCPKCDE_01151 6.5e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HGCPKCDE_01152 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HGCPKCDE_01153 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HGCPKCDE_01154 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HGCPKCDE_01155 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGCPKCDE_01156 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HGCPKCDE_01157 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HGCPKCDE_01158 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HGCPKCDE_01159 9.2e-101 folE 3.5.4.16 H GTP cyclohydrolase
HGCPKCDE_01160 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HGCPKCDE_01161 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HGCPKCDE_01162 2.3e-136 yphF
HGCPKCDE_01163 1.6e-18 yphE S Protein of unknown function (DUF2768)
HGCPKCDE_01164 8.6e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HGCPKCDE_01165 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HGCPKCDE_01166 1.8e-27 ypzH
HGCPKCDE_01167 2.5e-161 seaA S YIEGIA protein
HGCPKCDE_01168 1.3e-102 yphA
HGCPKCDE_01169 1.4e-07 S YpzI-like protein
HGCPKCDE_01170 1.3e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HGCPKCDE_01171 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HGCPKCDE_01172 3.6e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HGCPKCDE_01173 1.8e-23 S Family of unknown function (DUF5359)
HGCPKCDE_01174 1e-111 ypfA M Flagellar protein YcgR
HGCPKCDE_01175 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HGCPKCDE_01176 7.5e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HGCPKCDE_01177 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
HGCPKCDE_01178 1.3e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HGCPKCDE_01179 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HGCPKCDE_01180 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HGCPKCDE_01181 5.2e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
HGCPKCDE_01182 8.2e-81 ypbF S Protein of unknown function (DUF2663)
HGCPKCDE_01183 1.3e-75 ypbE M Lysin motif
HGCPKCDE_01184 1.1e-99 ypbD S metal-dependent membrane protease
HGCPKCDE_01185 9.2e-286 recQ 3.6.4.12 L DNA helicase
HGCPKCDE_01186 2.3e-198 ypbB 5.1.3.1 S protein conserved in bacteria
HGCPKCDE_01187 4.7e-41 fer C Ferredoxin
HGCPKCDE_01188 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HGCPKCDE_01189 2.6e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGCPKCDE_01190 2.2e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HGCPKCDE_01191 8.3e-199 rsiX
HGCPKCDE_01192 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HGCPKCDE_01193 0.0 resE 2.7.13.3 T Histidine kinase
HGCPKCDE_01194 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCPKCDE_01195 6.7e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HGCPKCDE_01196 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HGCPKCDE_01197 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HGCPKCDE_01198 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HGCPKCDE_01199 1.9e-87 spmB S Spore maturation protein
HGCPKCDE_01200 3.5e-103 spmA S Spore maturation protein
HGCPKCDE_01201 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HGCPKCDE_01202 7.6e-97 ypuI S Protein of unknown function (DUF3907)
HGCPKCDE_01203 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HGCPKCDE_01204 1.3e-126 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HGCPKCDE_01205 2.1e-91 ypuF S Domain of unknown function (DUF309)
HGCPKCDE_01206 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCPKCDE_01207 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HGCPKCDE_01208 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HGCPKCDE_01209 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
HGCPKCDE_01210 4.2e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGCPKCDE_01211 6e-55 ypuD
HGCPKCDE_01212 5.4e-98 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HGCPKCDE_01213 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HGCPKCDE_01214 9.1e-16 S SNARE associated Golgi protein
HGCPKCDE_01216 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGCPKCDE_01217 3.6e-149 ypuA S Secreted protein
HGCPKCDE_01218 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HGCPKCDE_01219 1.4e-273 spoVAF EG Stage V sporulation protein AF
HGCPKCDE_01220 1.4e-110 spoVAEA S stage V sporulation protein
HGCPKCDE_01221 2.2e-57 spoVAEB S stage V sporulation protein
HGCPKCDE_01222 9e-192 spoVAD I Stage V sporulation protein AD
HGCPKCDE_01223 2.3e-78 spoVAC S stage V sporulation protein AC
HGCPKCDE_01224 1e-67 spoVAB S Stage V sporulation protein AB
HGCPKCDE_01225 9.6e-112 spoVAA S Stage V sporulation protein AA
HGCPKCDE_01226 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCPKCDE_01227 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HGCPKCDE_01228 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HGCPKCDE_01229 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HGCPKCDE_01230 3.8e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HGCPKCDE_01231 6.7e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGCPKCDE_01232 2.6e-166 xerD L recombinase XerD
HGCPKCDE_01233 3.7e-37 S Protein of unknown function (DUF4227)
HGCPKCDE_01234 2e-79 fur P Belongs to the Fur family
HGCPKCDE_01235 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HGCPKCDE_01236 2e-32 yqkK
HGCPKCDE_01237 5.5e-242 mleA 1.1.1.38 C malic enzyme
HGCPKCDE_01238 3.1e-235 mleN C Na H antiporter
HGCPKCDE_01239 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HGCPKCDE_01240 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HGCPKCDE_01241 4.5e-58 ansR K Transcriptional regulator
HGCPKCDE_01242 3e-223 yqxK 3.6.4.12 L DNA helicase
HGCPKCDE_01243 5.8e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HGCPKCDE_01245 7.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HGCPKCDE_01246 3.1e-12 yqkE S Protein of unknown function (DUF3886)
HGCPKCDE_01247 2.7e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HGCPKCDE_01248 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HGCPKCDE_01249 2.8e-54 yqkB S Belongs to the HesB IscA family
HGCPKCDE_01250 1.5e-194 yqkA K GrpB protein
HGCPKCDE_01251 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HGCPKCDE_01252 3.6e-87 yqjY K acetyltransferase
HGCPKCDE_01253 2.2e-49 S YolD-like protein
HGCPKCDE_01254 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGCPKCDE_01255 1.7e-224 yqjV G Major Facilitator Superfamily
HGCPKCDE_01257 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCPKCDE_01258 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
HGCPKCDE_01259 7.6e-263 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HGCPKCDE_01260 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCPKCDE_01261 4.8e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HGCPKCDE_01262 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGCPKCDE_01263 0.0 rocB E arginine degradation protein
HGCPKCDE_01264 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HGCPKCDE_01265 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HGCPKCDE_01266 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HGCPKCDE_01267 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HGCPKCDE_01268 1.4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HGCPKCDE_01269 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGCPKCDE_01270 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGCPKCDE_01271 4.5e-24 yqzJ
HGCPKCDE_01272 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGCPKCDE_01273 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
HGCPKCDE_01274 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HGCPKCDE_01275 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HGCPKCDE_01276 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HGCPKCDE_01278 1.4e-98 yqjB S protein conserved in bacteria
HGCPKCDE_01279 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
HGCPKCDE_01280 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HGCPKCDE_01281 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HGCPKCDE_01282 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
HGCPKCDE_01283 9.3e-77 yqiW S Belongs to the UPF0403 family
HGCPKCDE_01284 2.6e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HGCPKCDE_01285 2.3e-207 norA EGP Major facilitator Superfamily
HGCPKCDE_01286 4.9e-151 bmrR K helix_turn_helix, mercury resistance
HGCPKCDE_01287 4.4e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGCPKCDE_01288 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HGCPKCDE_01289 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HGCPKCDE_01290 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HGCPKCDE_01291 8.7e-201 buk 2.7.2.7 C Belongs to the acetokinase family
HGCPKCDE_01292 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HGCPKCDE_01293 5.1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HGCPKCDE_01294 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HGCPKCDE_01295 4e-34 yqzF S Protein of unknown function (DUF2627)
HGCPKCDE_01296 1.1e-161 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HGCPKCDE_01297 3.1e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HGCPKCDE_01298 9.9e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HGCPKCDE_01299 1.3e-210 mmgC I acyl-CoA dehydrogenase
HGCPKCDE_01300 9.8e-155 hbdA 1.1.1.157 I Dehydrogenase
HGCPKCDE_01301 5.9e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
HGCPKCDE_01302 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HGCPKCDE_01303 1.2e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HGCPKCDE_01304 6e-27
HGCPKCDE_01305 1.4e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HGCPKCDE_01307 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HGCPKCDE_01308 2.8e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HGCPKCDE_01309 5.7e-295 recN L May be involved in recombinational repair of damaged DNA
HGCPKCDE_01310 3.9e-78 argR K Regulates arginine biosynthesis genes
HGCPKCDE_01311 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HGCPKCDE_01312 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HGCPKCDE_01313 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGCPKCDE_01314 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGCPKCDE_01315 2.5e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGCPKCDE_01316 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGCPKCDE_01317 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGCPKCDE_01318 2.1e-67 yqhY S protein conserved in bacteria
HGCPKCDE_01319 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HGCPKCDE_01320 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HGCPKCDE_01321 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HGCPKCDE_01322 1.4e-108 spoIIIAG S stage III sporulation protein AG
HGCPKCDE_01323 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HGCPKCDE_01324 1.3e-197 spoIIIAE S stage III sporulation protein AE
HGCPKCDE_01325 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HGCPKCDE_01326 7.6e-29 spoIIIAC S stage III sporulation protein AC
HGCPKCDE_01327 2.9e-85 spoIIIAB S Stage III sporulation protein
HGCPKCDE_01328 1.2e-171 spoIIIAA S stage III sporulation protein AA
HGCPKCDE_01329 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HGCPKCDE_01330 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HGCPKCDE_01331 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HGCPKCDE_01332 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HGCPKCDE_01333 3e-93 yqhR S Conserved membrane protein YqhR
HGCPKCDE_01334 3e-173 yqhQ S Protein of unknown function (DUF1385)
HGCPKCDE_01335 2.2e-61 yqhP
HGCPKCDE_01336 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
HGCPKCDE_01337 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HGCPKCDE_01338 2.8e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HGCPKCDE_01339 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HGCPKCDE_01340 4.5e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HGCPKCDE_01341 3.2e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HGCPKCDE_01342 4e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HGCPKCDE_01343 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HGCPKCDE_01344 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HGCPKCDE_01345 1.2e-24 sinI S Anti-repressor SinI
HGCPKCDE_01346 1e-54 sinR K transcriptional
HGCPKCDE_01347 2.5e-141 tasA S Cell division protein FtsN
HGCPKCDE_01348 6.7e-59 sipW 3.4.21.89 U Signal peptidase
HGCPKCDE_01349 1.3e-113 yqxM
HGCPKCDE_01350 7.3e-54 yqzG S Protein of unknown function (DUF3889)
HGCPKCDE_01351 4.4e-25 yqzE S YqzE-like protein
HGCPKCDE_01352 1.8e-44 S ComG operon protein 7
HGCPKCDE_01353 1.3e-34 comGF U Putative Competence protein ComGF
HGCPKCDE_01354 1.3e-57 comGE
HGCPKCDE_01355 2.2e-70 gspH NU protein transport across the cell outer membrane
HGCPKCDE_01356 6.8e-47 comGC U Required for transformation and DNA binding
HGCPKCDE_01357 3e-174 comGB NU COG1459 Type II secretory pathway, component PulF
HGCPKCDE_01358 8.6e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HGCPKCDE_01360 4e-173 corA P Mg2 transporter protein
HGCPKCDE_01361 2e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HGCPKCDE_01362 6.4e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGCPKCDE_01364 2.3e-63 yqgZ 1.20.4.1 P Belongs to the ArsC family
HGCPKCDE_01365 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HGCPKCDE_01366 8e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HGCPKCDE_01367 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HGCPKCDE_01368 6.9e-50 yqgV S Thiamine-binding protein
HGCPKCDE_01369 6.1e-199 yqgU
HGCPKCDE_01370 2.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HGCPKCDE_01371 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HGCPKCDE_01372 3.4e-180 glcK 2.7.1.2 G Glucokinase
HGCPKCDE_01373 3.1e-33 yqgQ S Protein conserved in bacteria
HGCPKCDE_01374 3.7e-266 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HGCPKCDE_01375 2.5e-09 yqgO
HGCPKCDE_01376 2.5e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HGCPKCDE_01377 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HGCPKCDE_01378 2.3e-201 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HGCPKCDE_01380 9.2e-51 yqzD
HGCPKCDE_01381 2.1e-71 yqzC S YceG-like family
HGCPKCDE_01382 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGCPKCDE_01383 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGCPKCDE_01384 2.2e-157 pstA P Phosphate transport system permease
HGCPKCDE_01385 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HGCPKCDE_01386 1.7e-149 pstS P Phosphate
HGCPKCDE_01387 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HGCPKCDE_01388 2.5e-231 yqgE EGP Major facilitator superfamily
HGCPKCDE_01389 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HGCPKCDE_01390 4e-73 yqgC S protein conserved in bacteria
HGCPKCDE_01391 3.9e-131 yqgB S Protein of unknown function (DUF1189)
HGCPKCDE_01392 2.6e-46 yqfZ M LysM domain
HGCPKCDE_01393 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HGCPKCDE_01394 4.3e-62 yqfX S membrane
HGCPKCDE_01395 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HGCPKCDE_01396 1.9e-77 zur P Belongs to the Fur family
HGCPKCDE_01397 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HGCPKCDE_01398 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HGCPKCDE_01399 2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HGCPKCDE_01400 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HGCPKCDE_01402 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HGCPKCDE_01403 4.8e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HGCPKCDE_01404 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
HGCPKCDE_01405 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HGCPKCDE_01406 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HGCPKCDE_01407 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HGCPKCDE_01408 4.5e-88 yaiI S Belongs to the UPF0178 family
HGCPKCDE_01409 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HGCPKCDE_01410 4.5e-112 ccpN K CBS domain
HGCPKCDE_01411 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HGCPKCDE_01412 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HGCPKCDE_01413 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
HGCPKCDE_01414 8.4e-19 S YqzL-like protein
HGCPKCDE_01415 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HGCPKCDE_01416 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HGCPKCDE_01417 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HGCPKCDE_01418 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HGCPKCDE_01419 0.0 yqfF S membrane-associated HD superfamily hydrolase
HGCPKCDE_01421 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
HGCPKCDE_01422 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HGCPKCDE_01423 2.7e-45 yqfC S sporulation protein YqfC
HGCPKCDE_01424 3.7e-22 yqfB
HGCPKCDE_01425 4.3e-122 yqfA S UPF0365 protein
HGCPKCDE_01426 1.7e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HGCPKCDE_01427 2.5e-61 yqeY S Yqey-like protein
HGCPKCDE_01428 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HGCPKCDE_01429 8.2e-158 yqeW P COG1283 Na phosphate symporter
HGCPKCDE_01430 6.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HGCPKCDE_01431 7.2e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HGCPKCDE_01432 5.4e-175 prmA J Methylates ribosomal protein L11
HGCPKCDE_01433 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HGCPKCDE_01434 0.0 dnaK O Heat shock 70 kDa protein
HGCPKCDE_01435 1.5e-74 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HGCPKCDE_01436 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HGCPKCDE_01437 5.3e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HGCPKCDE_01438 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HGCPKCDE_01439 7.2e-53 yqxA S Protein of unknown function (DUF3679)
HGCPKCDE_01440 1.5e-222 spoIIP M stage II sporulation protein P
HGCPKCDE_01441 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HGCPKCDE_01442 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HGCPKCDE_01443 1.9e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
HGCPKCDE_01444 4.1e-15 S YqzM-like protein
HGCPKCDE_01445 0.0 comEC S Competence protein ComEC
HGCPKCDE_01446 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HGCPKCDE_01447 1.1e-104 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HGCPKCDE_01448 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGCPKCDE_01449 2.9e-139 yqeM Q Methyltransferase
HGCPKCDE_01450 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HGCPKCDE_01451 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HGCPKCDE_01452 3.8e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HGCPKCDE_01453 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HGCPKCDE_01454 1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HGCPKCDE_01455 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HGCPKCDE_01456 5.3e-95 yqeG S hydrolase of the HAD superfamily
HGCPKCDE_01458 1.8e-141 yqeF E GDSL-like Lipase/Acylhydrolase
HGCPKCDE_01459 2.7e-132 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HGCPKCDE_01460 1.4e-102 yqeD S SNARE associated Golgi protein
HGCPKCDE_01461 2.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HGCPKCDE_01462 2.3e-133 yqeB
HGCPKCDE_01463 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HGCPKCDE_01464 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCPKCDE_01465 4.2e-278 cisA2 L Recombinase
HGCPKCDE_01466 8.5e-174 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HGCPKCDE_01467 2.3e-112 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCPKCDE_01468 1.3e-124 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCPKCDE_01469 7.4e-197 OPR C NADH:flavin oxidoreductase / NADH oxidase family
HGCPKCDE_01470 8.1e-154 E TAP-like protein
HGCPKCDE_01471 1.2e-95 K QacR-like protein, C-terminal region
HGCPKCDE_01472 4.6e-149 K Helix-turn-helix XRE-family like proteins
HGCPKCDE_01473 3.5e-222 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HGCPKCDE_01474 2.2e-27 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HGCPKCDE_01475 3e-59 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCPKCDE_01476 5.2e-53 arsR K ArsR family transcriptional regulator
HGCPKCDE_01477 2.8e-30 yqcI S YqcI/YcgG family
HGCPKCDE_01478 1.8e-62 K BetI-type transcriptional repressor, C-terminal
HGCPKCDE_01479 2.7e-140 yhfP 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HGCPKCDE_01480 3.3e-65 S response regulator aspartate phosphatase
HGCPKCDE_01482 7.6e-28
HGCPKCDE_01483 3.5e-162 yobL S Bacterial EndoU nuclease
HGCPKCDE_01484 1.3e-25 S SMI1-KNR4 cell-wall
HGCPKCDE_01485 2.1e-70 yokH G SMI1 / KNR4 family
HGCPKCDE_01486 2.4e-56 V HNH endonuclease
HGCPKCDE_01487 3.5e-92 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HGCPKCDE_01488 1.3e-27 S phage terminase, large subunit
HGCPKCDE_01489 3.4e-48 yqaS L DNA packaging
HGCPKCDE_01491 3.7e-26 cotD S Inner spore coat protein D
HGCPKCDE_01493 3e-21 yqaO S Phage-like element PBSX protein XtrA
HGCPKCDE_01494 7.6e-160 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HGCPKCDE_01495 2e-89 K Transcriptional regulator PadR-like family
HGCPKCDE_01496 3.9e-101 adk 2.7.4.3 F adenylate kinase activity
HGCPKCDE_01498 1.2e-94 yqaB E IrrE N-terminal-like domain
HGCPKCDE_01499 1e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCPKCDE_01500 9e-237 yrkQ T Histidine kinase
HGCPKCDE_01501 1.1e-127 T Transcriptional regulator
HGCPKCDE_01502 4.1e-223 yrkO P Protein of unknown function (DUF418)
HGCPKCDE_01503 1.1e-103 yrkN K Acetyltransferase (GNAT) family
HGCPKCDE_01504 1.5e-97 ywrO S Flavodoxin-like fold
HGCPKCDE_01505 2.8e-79 S Protein of unknown function with HXXEE motif
HGCPKCDE_01506 1.7e-100 yrkJ S membrane transporter protein
HGCPKCDE_01507 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HGCPKCDE_01508 1.4e-206 yrkH P Rhodanese Homology Domain
HGCPKCDE_01509 3.9e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
HGCPKCDE_01510 4.7e-82 yrkE O DsrE/DsrF/DrsH-like family
HGCPKCDE_01511 7.8e-39 yrkD S protein conserved in bacteria
HGCPKCDE_01512 2.2e-107 yrkC G Cupin domain
HGCPKCDE_01513 3.8e-148 bltR K helix_turn_helix, mercury resistance
HGCPKCDE_01514 1.1e-209 blt EGP Major facilitator Superfamily
HGCPKCDE_01515 5.9e-82 bltD 2.3.1.57 K FR47-like protein
HGCPKCDE_01516 1.9e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HGCPKCDE_01517 3.9e-16 S YrzO-like protein
HGCPKCDE_01518 1.2e-169 yrdR EG EamA-like transporter family
HGCPKCDE_01519 1e-159 yrdQ K Transcriptional regulator
HGCPKCDE_01520 1e-198 trkA P Oxidoreductase
HGCPKCDE_01521 4.4e-148 czcD P COG1230 Co Zn Cd efflux system component
HGCPKCDE_01522 3.8e-66 yodA S tautomerase
HGCPKCDE_01523 2.1e-160 gltR K LysR substrate binding domain
HGCPKCDE_01524 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
HGCPKCDE_01525 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HGCPKCDE_01526 2.8e-137 azlC E AzlC protein
HGCPKCDE_01527 2.2e-79 bkdR K helix_turn_helix ASNC type
HGCPKCDE_01528 4.1e-46 yrdF K ribonuclease inhibitor
HGCPKCDE_01529 4e-226 cypA C Cytochrome P450
HGCPKCDE_01530 3e-64 K Transcriptional regulator
HGCPKCDE_01531 1.2e-164 scrR K transcriptional
HGCPKCDE_01532 2e-228 msmE G Bacterial extracellular solute-binding protein
HGCPKCDE_01533 1.8e-149 msmF P Binding-protein-dependent transport system inner membrane component
HGCPKCDE_01534 6.7e-140 msmG P PFAM binding-protein-dependent transport systems inner membrane component
HGCPKCDE_01535 8.8e-197 rafB P LacY proton/sugar symporter
HGCPKCDE_01536 5.1e-252 cscA 3.2.1.26 GH32 G invertase
HGCPKCDE_01537 4.8e-111 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
HGCPKCDE_01538 1.5e-71 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
HGCPKCDE_01539 1.5e-98 yrdC 3.5.1.19 Q Isochorismatase family
HGCPKCDE_01540 1.4e-55 S Protein of unknown function (DUF2568)
HGCPKCDE_01541 2.1e-88 yrdA S DinB family
HGCPKCDE_01542 3.5e-165 aadK G Streptomycin adenylyltransferase
HGCPKCDE_01543 6.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HGCPKCDE_01544 4.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HGCPKCDE_01545 1.6e-123 yrpD S Domain of unknown function, YrpD
HGCPKCDE_01547 1.4e-112 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HGCPKCDE_01548 3.3e-92 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HGCPKCDE_01549 6.5e-187 yrpG C Aldo/keto reductase family
HGCPKCDE_01550 9.5e-226 yraO C Citrate transporter
HGCPKCDE_01551 1.3e-162 yraN K Transcriptional regulator
HGCPKCDE_01552 3.2e-203 yraM S PrpF protein
HGCPKCDE_01553 1.2e-149 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HGCPKCDE_01554 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCPKCDE_01555 6.2e-151 S Alpha beta hydrolase
HGCPKCDE_01556 1.7e-60 T sh3 domain protein
HGCPKCDE_01557 2.4e-61 T sh3 domain protein
HGCPKCDE_01559 3.8e-66 E Glyoxalase-like domain
HGCPKCDE_01560 1.5e-36 yraG
HGCPKCDE_01561 6.4e-63 yraF M Spore coat protein
HGCPKCDE_01562 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HGCPKCDE_01563 7.5e-26 yraE
HGCPKCDE_01564 3.6e-48 yraD M Spore coat protein
HGCPKCDE_01565 1.6e-46 yraB K helix_turn_helix, mercury resistance
HGCPKCDE_01566 6.2e-196 adhA 1.1.1.1 C alcohol dehydrogenase
HGCPKCDE_01567 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HGCPKCDE_01568 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HGCPKCDE_01569 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HGCPKCDE_01570 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HGCPKCDE_01571 6.9e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HGCPKCDE_01572 4.3e-74 levD 2.7.1.202 G PTS system fructose IIA component
HGCPKCDE_01573 0.0 levR K PTS system fructose IIA component
HGCPKCDE_01574 1e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HGCPKCDE_01575 3.6e-106 yrhP E LysE type translocator
HGCPKCDE_01576 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
HGCPKCDE_01577 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HGCPKCDE_01578 2.1e-149 rsiV S Protein of unknown function (DUF3298)
HGCPKCDE_01579 0.0 yrhL I Acyltransferase family
HGCPKCDE_01580 1.3e-45 yrhK S YrhK-like protein
HGCPKCDE_01581 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HGCPKCDE_01582 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HGCPKCDE_01583 6.5e-96 yrhH Q methyltransferase
HGCPKCDE_01586 1.8e-142 focA P Formate nitrite
HGCPKCDE_01587 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
HGCPKCDE_01588 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HGCPKCDE_01589 1.4e-78 yrhD S Protein of unknown function (DUF1641)
HGCPKCDE_01590 4.6e-35 yrhC S YrhC-like protein
HGCPKCDE_01591 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HGCPKCDE_01592 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HGCPKCDE_01593 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HGCPKCDE_01594 7.6e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HGCPKCDE_01595 2.9e-25 yrzA S Protein of unknown function (DUF2536)
HGCPKCDE_01596 4.2e-63 yrrS S Protein of unknown function (DUF1510)
HGCPKCDE_01597 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HGCPKCDE_01598 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGCPKCDE_01599 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HGCPKCDE_01600 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HGCPKCDE_01601 2.9e-173 yegQ O Peptidase U32
HGCPKCDE_01602 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
HGCPKCDE_01603 5.3e-182 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HGCPKCDE_01604 1.6e-45 yrzB S Belongs to the UPF0473 family
HGCPKCDE_01605 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HGCPKCDE_01606 1.7e-41 yrzL S Belongs to the UPF0297 family
HGCPKCDE_01607 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HGCPKCDE_01608 7.8e-170 yrrI S AI-2E family transporter
HGCPKCDE_01609 2.9e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HGCPKCDE_01610 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
HGCPKCDE_01611 1.8e-108 gluC P ABC transporter
HGCPKCDE_01612 7.6e-107 glnP P ABC transporter
HGCPKCDE_01613 8e-08 S Protein of unknown function (DUF3918)
HGCPKCDE_01614 9.8e-31 yrzR
HGCPKCDE_01615 7.8e-82 yrrD S protein conserved in bacteria
HGCPKCDE_01616 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HGCPKCDE_01617 1.4e-15 S COG0457 FOG TPR repeat
HGCPKCDE_01618 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HGCPKCDE_01619 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
HGCPKCDE_01620 1.2e-70 cymR K Transcriptional regulator
HGCPKCDE_01621 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HGCPKCDE_01622 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HGCPKCDE_01623 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HGCPKCDE_01624 7.5e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HGCPKCDE_01626 1.5e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
HGCPKCDE_01627 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HGCPKCDE_01628 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGCPKCDE_01629 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HGCPKCDE_01630 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HGCPKCDE_01631 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HGCPKCDE_01632 3.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HGCPKCDE_01633 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HGCPKCDE_01634 1.6e-48 yrzD S Post-transcriptional regulator
HGCPKCDE_01635 1.7e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGCPKCDE_01636 3.2e-113 yrbG S membrane
HGCPKCDE_01637 1.2e-74 yrzE S Protein of unknown function (DUF3792)
HGCPKCDE_01638 1.1e-38 yajC U Preprotein translocase subunit YajC
HGCPKCDE_01639 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HGCPKCDE_01640 7.5e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HGCPKCDE_01641 4.5e-18 yrzS S Protein of unknown function (DUF2905)
HGCPKCDE_01642 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HGCPKCDE_01643 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HGCPKCDE_01644 4.8e-93 bofC S BofC C-terminal domain
HGCPKCDE_01645 5.3e-253 csbX EGP Major facilitator Superfamily
HGCPKCDE_01646 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HGCPKCDE_01647 9.4e-118 yrzF T serine threonine protein kinase
HGCPKCDE_01649 3.1e-51 S Family of unknown function (DUF5412)
HGCPKCDE_01650 2e-261 alsT E Sodium alanine symporter
HGCPKCDE_01651 4.2e-127 yebC K transcriptional regulatory protein
HGCPKCDE_01652 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGCPKCDE_01653 1.7e-157 safA M spore coat assembly protein SafA
HGCPKCDE_01654 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HGCPKCDE_01655 7.3e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HGCPKCDE_01656 7.3e-305 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HGCPKCDE_01657 3.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
HGCPKCDE_01658 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
HGCPKCDE_01659 1.7e-162 pheA 4.2.1.51 E Prephenate dehydratase
HGCPKCDE_01660 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HGCPKCDE_01661 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HGCPKCDE_01662 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HGCPKCDE_01663 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HGCPKCDE_01664 4.1e-56 ysxB J ribosomal protein
HGCPKCDE_01665 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HGCPKCDE_01666 9.2e-161 spoIVFB S Stage IV sporulation protein
HGCPKCDE_01667 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HGCPKCDE_01668 2.5e-144 minD D Belongs to the ParA family
HGCPKCDE_01669 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HGCPKCDE_01670 1.4e-84 mreD M shape-determining protein
HGCPKCDE_01671 1.1e-156 mreC M Involved in formation and maintenance of cell shape
HGCPKCDE_01672 2.5e-184 mreB D Rod shape-determining protein MreB
HGCPKCDE_01673 2.8e-102 maf D septum formation protein Maf
HGCPKCDE_01674 8.9e-168 spoIIB S Sporulation related domain
HGCPKCDE_01675 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HGCPKCDE_01676 1.2e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HGCPKCDE_01677 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HGCPKCDE_01678 1.6e-25
HGCPKCDE_01679 2.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HGCPKCDE_01680 6.4e-206 spoVID M stage VI sporulation protein D
HGCPKCDE_01681 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HGCPKCDE_01682 6.2e-182 hemB 4.2.1.24 H Belongs to the ALAD family
HGCPKCDE_01683 1.2e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HGCPKCDE_01684 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HGCPKCDE_01685 3.6e-146 hemX O cytochrome C
HGCPKCDE_01686 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HGCPKCDE_01687 7e-89 ysxD
HGCPKCDE_01688 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HGCPKCDE_01689 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HGCPKCDE_01690 2.1e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HGCPKCDE_01691 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HGCPKCDE_01692 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HGCPKCDE_01693 1.1e-186 ysoA H Tetratricopeptide repeat
HGCPKCDE_01694 9.9e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HGCPKCDE_01695 6.3e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HGCPKCDE_01696 1.3e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HGCPKCDE_01697 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HGCPKCDE_01698 9.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HGCPKCDE_01699 9.3e-84 ilvN 2.2.1.6 E Acetolactate synthase
HGCPKCDE_01700 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HGCPKCDE_01701 3.2e-80 ysnE K acetyltransferase
HGCPKCDE_01702 9.1e-134 ysnF S protein conserved in bacteria
HGCPKCDE_01704 1.5e-91 ysnB S Phosphoesterase
HGCPKCDE_01705 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HGCPKCDE_01706 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HGCPKCDE_01707 6.5e-196 gerM S COG5401 Spore germination protein
HGCPKCDE_01708 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HGCPKCDE_01709 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HGCPKCDE_01710 3.3e-30 gerE K Transcriptional regulator
HGCPKCDE_01711 1.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HGCPKCDE_01712 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HGCPKCDE_01713 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HGCPKCDE_01714 2.4e-107 sdhC C succinate dehydrogenase
HGCPKCDE_01715 1.2e-79 yslB S Protein of unknown function (DUF2507)
HGCPKCDE_01716 5.4e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HGCPKCDE_01717 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HGCPKCDE_01718 2e-52 trxA O Belongs to the thioredoxin family
HGCPKCDE_01719 4.9e-303 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HGCPKCDE_01721 7.9e-177 etfA C Electron transfer flavoprotein
HGCPKCDE_01722 4.5e-135 etfB C Electron transfer flavoprotein
HGCPKCDE_01723 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HGCPKCDE_01724 2.7e-100 fadR K Transcriptional regulator
HGCPKCDE_01725 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HGCPKCDE_01726 7.3e-68 yshE S membrane
HGCPKCDE_01727 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HGCPKCDE_01728 0.0 polX L COG1796 DNA polymerase IV (family X)
HGCPKCDE_01729 1.3e-85 cvpA S membrane protein, required for colicin V production
HGCPKCDE_01730 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HGCPKCDE_01731 1.3e-165 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGCPKCDE_01732 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGCPKCDE_01733 3.1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HGCPKCDE_01734 8.5e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGCPKCDE_01735 2.6e-32 sspI S Belongs to the SspI family
HGCPKCDE_01736 2.9e-204 ysfB KT regulator
HGCPKCDE_01737 1.6e-263 glcD 1.1.3.15 C Glycolate oxidase subunit
HGCPKCDE_01738 3.6e-257 glcF C Glycolate oxidase
HGCPKCDE_01739 6.2e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
HGCPKCDE_01741 0.0 cstA T Carbon starvation protein
HGCPKCDE_01742 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HGCPKCDE_01743 2.9e-143 araQ G transport system permease
HGCPKCDE_01744 1.4e-167 araP G carbohydrate transport
HGCPKCDE_01745 2e-252 araN G carbohydrate transport
HGCPKCDE_01746 2e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HGCPKCDE_01747 1e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HGCPKCDE_01748 3.5e-131 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HGCPKCDE_01749 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HGCPKCDE_01750 6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HGCPKCDE_01751 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HGCPKCDE_01752 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
HGCPKCDE_01753 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HGCPKCDE_01754 1.7e-44 ysdA S Membrane
HGCPKCDE_01755 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HGCPKCDE_01756 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HGCPKCDE_01757 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HGCPKCDE_01759 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HGCPKCDE_01760 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HGCPKCDE_01761 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
HGCPKCDE_01762 0.0 lytS 2.7.13.3 T Histidine kinase
HGCPKCDE_01763 7.3e-149 ysaA S HAD-hyrolase-like
HGCPKCDE_01764 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGCPKCDE_01765 3.8e-159 ytxC S YtxC-like family
HGCPKCDE_01766 1.2e-109 ytxB S SNARE associated Golgi protein
HGCPKCDE_01767 6.6e-173 dnaI L Primosomal protein DnaI
HGCPKCDE_01768 2.9e-265 dnaB L Membrane attachment protein
HGCPKCDE_01769 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HGCPKCDE_01770 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HGCPKCDE_01771 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGCPKCDE_01772 9.9e-67 ytcD K Transcriptional regulator
HGCPKCDE_01773 2.1e-200 ytbD EGP Major facilitator Superfamily
HGCPKCDE_01774 8.9e-161 ytbE S reductase
HGCPKCDE_01775 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HGCPKCDE_01776 2.8e-106 ytaF P Probably functions as a manganese efflux pump
HGCPKCDE_01777 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HGCPKCDE_01778 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGCPKCDE_01779 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HGCPKCDE_01780 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCPKCDE_01781 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HGCPKCDE_01782 4.1e-242 icd 1.1.1.42 C isocitrate
HGCPKCDE_01783 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HGCPKCDE_01784 4.7e-71 yeaL S membrane
HGCPKCDE_01785 5.8e-192 ytvI S sporulation integral membrane protein YtvI
HGCPKCDE_01786 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HGCPKCDE_01787 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HGCPKCDE_01788 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HGCPKCDE_01789 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HGCPKCDE_01790 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HGCPKCDE_01791 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HGCPKCDE_01792 0.0 dnaE 2.7.7.7 L DNA polymerase
HGCPKCDE_01793 3.2e-56 ytrH S Sporulation protein YtrH
HGCPKCDE_01794 2.4e-68 ytrI
HGCPKCDE_01795 9.2e-29
HGCPKCDE_01796 5.1e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HGCPKCDE_01797 2.4e-47 ytpI S YtpI-like protein
HGCPKCDE_01798 8e-241 ytoI K transcriptional regulator containing CBS domains
HGCPKCDE_01799 1.2e-158 ytnM S membrane transporter protein
HGCPKCDE_01800 1.6e-238 ytnL 3.5.1.47 E hydrolase activity
HGCPKCDE_01801 1.2e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HGCPKCDE_01802 1.4e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCPKCDE_01803 8.4e-47 ytnI O COG0695 Glutaredoxin and related proteins
HGCPKCDE_01804 3.4e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCPKCDE_01805 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HGCPKCDE_01806 1.9e-119 tcyM U Binding-protein-dependent transport system inner membrane component
HGCPKCDE_01807 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
HGCPKCDE_01808 3.2e-144 tcyK M Bacterial periplasmic substrate-binding proteins
HGCPKCDE_01809 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
HGCPKCDE_01810 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
HGCPKCDE_01811 3.6e-171 ytlI K LysR substrate binding domain
HGCPKCDE_01812 1.7e-130 ytkL S Belongs to the UPF0173 family
HGCPKCDE_01813 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCPKCDE_01815 8.9e-267 argH 4.3.2.1 E argininosuccinate lyase
HGCPKCDE_01816 6.7e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HGCPKCDE_01817 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HGCPKCDE_01818 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGCPKCDE_01819 1.6e-164 ytxK 2.1.1.72 L DNA methylase
HGCPKCDE_01820 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HGCPKCDE_01821 8.7e-70 ytfJ S Sporulation protein YtfJ
HGCPKCDE_01822 8.1e-115 ytfI S Protein of unknown function (DUF2953)
HGCPKCDE_01823 8.5e-87 yteJ S RDD family
HGCPKCDE_01824 1.1e-178 sppA OU signal peptide peptidase SppA
HGCPKCDE_01825 3.1e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGCPKCDE_01826 0.0 ytcJ S amidohydrolase
HGCPKCDE_01827 5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HGCPKCDE_01828 2e-29 sspB S spore protein
HGCPKCDE_01829 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGCPKCDE_01830 2.3e-207 iscS2 2.8.1.7 E Cysteine desulfurase
HGCPKCDE_01831 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HGCPKCDE_01832 9.2e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HGCPKCDE_01833 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HGCPKCDE_01834 1e-108 yttP K Transcriptional regulator
HGCPKCDE_01835 1.3e-87 ytsP 1.8.4.14 T GAF domain-containing protein
HGCPKCDE_01836 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HGCPKCDE_01837 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HGCPKCDE_01839 1e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGCPKCDE_01840 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HGCPKCDE_01841 1.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HGCPKCDE_01842 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HGCPKCDE_01843 5.4e-225 acuC BQ histone deacetylase
HGCPKCDE_01844 1.4e-125 motS N Flagellar motor protein
HGCPKCDE_01845 1.8e-145 motA N flagellar motor
HGCPKCDE_01846 1.7e-182 ccpA K catabolite control protein A
HGCPKCDE_01847 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HGCPKCDE_01848 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
HGCPKCDE_01849 6.6e-17 ytxH S COG4980 Gas vesicle protein
HGCPKCDE_01850 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HGCPKCDE_01851 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HGCPKCDE_01852 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HGCPKCDE_01853 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGCPKCDE_01854 9.8e-149 ytpQ S Belongs to the UPF0354 family
HGCPKCDE_01855 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HGCPKCDE_01856 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HGCPKCDE_01857 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HGCPKCDE_01858 1.1e-50 ytzB S small secreted protein
HGCPKCDE_01859 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HGCPKCDE_01860 9.3e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HGCPKCDE_01861 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HGCPKCDE_01862 2e-45 ytzH S YtzH-like protein
HGCPKCDE_01863 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HGCPKCDE_01864 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HGCPKCDE_01865 1.1e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HGCPKCDE_01866 8.5e-165 ytlQ
HGCPKCDE_01867 1.2e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HGCPKCDE_01868 2.5e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HGCPKCDE_01869 1.7e-270 pepV 3.5.1.18 E Dipeptidase
HGCPKCDE_01870 2.1e-225 pbuO S permease
HGCPKCDE_01871 1.1e-201 ythQ U Bacterial ABC transporter protein EcsB
HGCPKCDE_01872 4.8e-131 ythP V ABC transporter
HGCPKCDE_01873 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HGCPKCDE_01874 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HGCPKCDE_01875 3.6e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGCPKCDE_01876 1.1e-231 ytfP S HI0933-like protein
HGCPKCDE_01877 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HGCPKCDE_01878 3.1e-26 yteV S Sporulation protein Cse60
HGCPKCDE_01879 4.5e-115 yteU S Integral membrane protein
HGCPKCDE_01880 1.1e-255 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HGCPKCDE_01881 5.1e-72 yteS G transport
HGCPKCDE_01882 5.2e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HGCPKCDE_01883 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HGCPKCDE_01884 0.0 ytdP K Transcriptional regulator
HGCPKCDE_01885 1.5e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HGCPKCDE_01886 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
HGCPKCDE_01887 9e-136 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HGCPKCDE_01888 5.5e-225 bioI 1.14.14.46 C Cytochrome P450
HGCPKCDE_01889 4.2e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HGCPKCDE_01890 2.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HGCPKCDE_01891 1e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HGCPKCDE_01892 2.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HGCPKCDE_01893 2.2e-139 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HGCPKCDE_01894 4.1e-172 ytaP S Acetyl xylan esterase (AXE1)
HGCPKCDE_01895 1.2e-188 msmR K Transcriptional regulator
HGCPKCDE_01896 1.4e-245 msmE G Bacterial extracellular solute-binding protein
HGCPKCDE_01897 6.2e-168 amyD P ABC transporter
HGCPKCDE_01898 4.4e-144 amyC P ABC transporter (permease)
HGCPKCDE_01899 4.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HGCPKCDE_01900 8.1e-51 ytwF P Sulfurtransferase
HGCPKCDE_01901 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGCPKCDE_01902 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HGCPKCDE_01903 2.4e-139 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HGCPKCDE_01904 3.9e-210 yttB EGP Major facilitator Superfamily
HGCPKCDE_01905 8.7e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HGCPKCDE_01906 0.0 bceB V ABC transporter (permease)
HGCPKCDE_01907 1.1e-138 bceA V ABC transporter, ATP-binding protein
HGCPKCDE_01908 1.8e-184 T PhoQ Sensor
HGCPKCDE_01909 2.6e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCPKCDE_01910 2.3e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HGCPKCDE_01911 3.1e-127 ytrE V ABC transporter, ATP-binding protein
HGCPKCDE_01912 2e-140
HGCPKCDE_01913 8.3e-150 P ABC-2 family transporter protein
HGCPKCDE_01914 4.2e-161 ytrB P abc transporter atp-binding protein
HGCPKCDE_01915 5.1e-66 ytrA K GntR family transcriptional regulator
HGCPKCDE_01917 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HGCPKCDE_01918 8.1e-190 yhcC S Fe-S oxidoreductase
HGCPKCDE_01919 2.8e-105 ytqB J Putative rRNA methylase
HGCPKCDE_01920 9.8e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HGCPKCDE_01921 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HGCPKCDE_01922 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HGCPKCDE_01923 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HGCPKCDE_01924 0.0 asnB 6.3.5.4 E Asparagine synthase
HGCPKCDE_01925 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HGCPKCDE_01926 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HGCPKCDE_01927 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HGCPKCDE_01928 2.7e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HGCPKCDE_01929 1.8e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HGCPKCDE_01930 1.4e-144 ytlC P ABC transporter
HGCPKCDE_01931 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HGCPKCDE_01932 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HGCPKCDE_01933 5.4e-63 ytkC S Bacteriophage holin family
HGCPKCDE_01934 2.1e-76 dps P Belongs to the Dps family
HGCPKCDE_01936 2.4e-72 ytkA S YtkA-like
HGCPKCDE_01937 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HGCPKCDE_01938 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HGCPKCDE_01939 3.6e-41 rpmE2 J Ribosomal protein L31
HGCPKCDE_01940 2.3e-248 cydA 1.10.3.14 C oxidase, subunit
HGCPKCDE_01941 1.1e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HGCPKCDE_01942 1.1e-24 S Domain of Unknown Function (DUF1540)
HGCPKCDE_01943 1.8e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HGCPKCDE_01944 3.9e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HGCPKCDE_01945 4.5e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HGCPKCDE_01946 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
HGCPKCDE_01947 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HGCPKCDE_01948 1.7e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HGCPKCDE_01949 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HGCPKCDE_01950 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HGCPKCDE_01951 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HGCPKCDE_01952 4.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
HGCPKCDE_01953 9.7e-132 dksA T COG1734 DnaK suppressor protein
HGCPKCDE_01954 2.1e-151 galU 2.7.7.9 M Nucleotidyl transferase
HGCPKCDE_01955 3.4e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGCPKCDE_01956 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HGCPKCDE_01957 3.7e-232 ytcC M Glycosyltransferase Family 4
HGCPKCDE_01959 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
HGCPKCDE_01960 1.8e-217 cotSA M Glycosyl transferases group 1
HGCPKCDE_01961 6.3e-204 cotI S Spore coat protein
HGCPKCDE_01962 6.4e-76 tspO T membrane
HGCPKCDE_01963 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HGCPKCDE_01964 3.2e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HGCPKCDE_01965 1.4e-176 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HGCPKCDE_01966 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HGCPKCDE_01967 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HGCPKCDE_01976 7.8e-08
HGCPKCDE_01977 1.3e-09
HGCPKCDE_01984 2e-08
HGCPKCDE_01989 0.0 fusAA Q Non-ribosomal peptide synthetase modules and related proteins
HGCPKCDE_01994 2e-08
HGCPKCDE_01999 6.2e-173 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGCPKCDE_02000 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HGCPKCDE_02001 6.2e-58 sbp S small basic protein
HGCPKCDE_02002 1e-102 ylxX S protein conserved in bacteria
HGCPKCDE_02003 2.4e-103 ylxW S protein conserved in bacteria
HGCPKCDE_02004 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HGCPKCDE_02005 5.3e-167 murB 1.3.1.98 M cell wall formation
HGCPKCDE_02006 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HGCPKCDE_02007 5.7e-186 spoVE D Belongs to the SEDS family
HGCPKCDE_02008 1.7e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HGCPKCDE_02009 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGCPKCDE_02010 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGCPKCDE_02011 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HGCPKCDE_02012 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HGCPKCDE_02013 3.7e-44 ftsL D Essential cell division protein
HGCPKCDE_02014 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HGCPKCDE_02015 2.9e-78 mraZ K Belongs to the MraZ family
HGCPKCDE_02016 2.1e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HGCPKCDE_02017 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGCPKCDE_02018 1.5e-88 ylbP K n-acetyltransferase
HGCPKCDE_02019 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HGCPKCDE_02020 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HGCPKCDE_02021 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HGCPKCDE_02023 2.8e-235 ylbM S Belongs to the UPF0348 family
HGCPKCDE_02024 1.2e-186 ylbL T Belongs to the peptidase S16 family
HGCPKCDE_02025 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HGCPKCDE_02026 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
HGCPKCDE_02027 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HGCPKCDE_02028 1.3e-96 rsmD 2.1.1.171 L Methyltransferase
HGCPKCDE_02029 3.7e-38 ylbG S UPF0298 protein
HGCPKCDE_02030 1.4e-55 ylbF S Belongs to the UPF0342 family
HGCPKCDE_02031 6.7e-37 ylbE S YlbE-like protein
HGCPKCDE_02032 4.1e-63 ylbD S Putative coat protein
HGCPKCDE_02033 1.6e-199 ylbC S protein with SCP PR1 domains
HGCPKCDE_02034 2.6e-74 ylbB T COG0517 FOG CBS domain
HGCPKCDE_02035 7e-62 ylbA S YugN-like family
HGCPKCDE_02036 8.8e-167 ctaG S cytochrome c oxidase
HGCPKCDE_02037 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HGCPKCDE_02038 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HGCPKCDE_02039 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HGCPKCDE_02040 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HGCPKCDE_02041 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HGCPKCDE_02042 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HGCPKCDE_02043 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HGCPKCDE_02044 1.2e-211 ftsW D Belongs to the SEDS family
HGCPKCDE_02045 2.5e-43 ylaN S Belongs to the UPF0358 family
HGCPKCDE_02046 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HGCPKCDE_02047 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HGCPKCDE_02048 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HGCPKCDE_02049 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGCPKCDE_02050 2.5e-32 ylaI S protein conserved in bacteria
HGCPKCDE_02051 4.2e-47 ylaH S YlaH-like protein
HGCPKCDE_02052 0.0 typA T GTP-binding protein TypA
HGCPKCDE_02053 8.2e-22 S Family of unknown function (DUF5325)
HGCPKCDE_02054 1.8e-38 ylaE
HGCPKCDE_02055 2.7e-11 sigC S Putative zinc-finger
HGCPKCDE_02056 9.6e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HGCPKCDE_02057 2.7e-42 ylaB
HGCPKCDE_02058 0.0 ylaA
HGCPKCDE_02059 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HGCPKCDE_02060 3.5e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HGCPKCDE_02061 5.8e-77 ykzC S Acetyltransferase (GNAT) family
HGCPKCDE_02062 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
HGCPKCDE_02063 7.1e-26 ykzI
HGCPKCDE_02064 2.1e-117 yktB S Belongs to the UPF0637 family
HGCPKCDE_02065 2e-42 yktA S Belongs to the UPF0223 family
HGCPKCDE_02066 1e-276 speA 4.1.1.19 E Arginine
HGCPKCDE_02067 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HGCPKCDE_02068 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HGCPKCDE_02069 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGCPKCDE_02070 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HGCPKCDE_02071 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HGCPKCDE_02072 3e-108 recN L Putative cell-wall binding lipoprotein
HGCPKCDE_02074 1.5e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGCPKCDE_02075 1.6e-146 ykrA S hydrolases of the HAD superfamily
HGCPKCDE_02076 8.2e-31 ykzG S Belongs to the UPF0356 family
HGCPKCDE_02077 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGCPKCDE_02078 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HGCPKCDE_02079 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HGCPKCDE_02080 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HGCPKCDE_02081 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HGCPKCDE_02082 1.5e-43 abrB K of stationary sporulation gene expression
HGCPKCDE_02083 2.9e-182 mreB D Rod-share determining protein MreBH
HGCPKCDE_02084 1.1e-12 S Uncharacterized protein YkpC
HGCPKCDE_02085 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HGCPKCDE_02086 4.8e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGCPKCDE_02087 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HGCPKCDE_02088 8.1e-39 ykoA
HGCPKCDE_02089 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HGCPKCDE_02090 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HGCPKCDE_02091 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HGCPKCDE_02092 3.1e-136 fruR K Transcriptional regulator
HGCPKCDE_02093 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HGCPKCDE_02094 2.7e-123 macB V ABC transporter, ATP-binding protein
HGCPKCDE_02095 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGCPKCDE_02096 8.5e-117 yknW S Yip1 domain
HGCPKCDE_02097 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HGCPKCDE_02098 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HGCPKCDE_02099 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HGCPKCDE_02100 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HGCPKCDE_02101 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HGCPKCDE_02102 2.4e-245 moeA 2.10.1.1 H molybdopterin
HGCPKCDE_02103 3.4e-191 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HGCPKCDE_02104 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HGCPKCDE_02105 1.2e-145 yknT
HGCPKCDE_02106 5.8e-95 rok K Repressor of ComK
HGCPKCDE_02107 6.3e-81 ykuV CO thiol-disulfide
HGCPKCDE_02108 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HGCPKCDE_02109 8.8e-142 ykuT M Mechanosensitive ion channel
HGCPKCDE_02110 1.7e-35 ykuS S Belongs to the UPF0180 family
HGCPKCDE_02111 4.9e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HGCPKCDE_02112 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HGCPKCDE_02113 3.9e-78 fld C Flavodoxin
HGCPKCDE_02114 7.5e-174 ykuO
HGCPKCDE_02115 3.7e-87 fld C Flavodoxin domain
HGCPKCDE_02116 3.5e-168 ccpC K Transcriptional regulator
HGCPKCDE_02117 1.6e-76 ykuL S CBS domain
HGCPKCDE_02118 3.9e-27 ykzF S Antirepressor AbbA
HGCPKCDE_02119 4.4e-94 ykuK S Ribonuclease H-like
HGCPKCDE_02120 3.9e-37 ykuJ S protein conserved in bacteria
HGCPKCDE_02121 5.2e-234 ykuI T Diguanylate phosphodiesterase
HGCPKCDE_02122 8.4e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCPKCDE_02123 9.4e-166 ykuE S Metallophosphoesterase
HGCPKCDE_02124 1.8e-87 ykuD S protein conserved in bacteria
HGCPKCDE_02125 1.2e-236 ykuC EGP Major facilitator Superfamily
HGCPKCDE_02126 1.7e-84 ykyB S YkyB-like protein
HGCPKCDE_02127 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HGCPKCDE_02128 3.7e-15
HGCPKCDE_02129 3.1e-220 patA 2.6.1.1 E Aminotransferase
HGCPKCDE_02130 0.0 pilS 2.7.13.3 T Histidine kinase
HGCPKCDE_02131 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HGCPKCDE_02132 4.5e-58 ykwD J protein with SCP PR1 domains
HGCPKCDE_02133 8e-44 ykwD J protein with SCP PR1 domains
HGCPKCDE_02134 3.6e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HGCPKCDE_02135 9.7e-259 mcpC NT chemotaxis protein
HGCPKCDE_02136 9.5e-129 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCPKCDE_02137 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
HGCPKCDE_02138 7.2e-39 splA S Transcriptional regulator
HGCPKCDE_02139 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGCPKCDE_02140 2.1e-39 ptsH G phosphocarrier protein HPr
HGCPKCDE_02141 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCPKCDE_02142 2.2e-127 glcT K antiterminator
HGCPKCDE_02143 3.5e-177 ykvZ 5.1.1.1 K Transcriptional regulator
HGCPKCDE_02144 2.4e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HGCPKCDE_02145 1e-09
HGCPKCDE_02146 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HGCPKCDE_02147 9.2e-89 stoA CO thiol-disulfide
HGCPKCDE_02148 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGCPKCDE_02149 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
HGCPKCDE_02150 2.8e-28
HGCPKCDE_02151 6e-25 ykvS S protein conserved in bacteria
HGCPKCDE_02152 1.6e-45 ykvR S Protein of unknown function (DUF3219)
HGCPKCDE_02153 1.7e-73 G Glycosyl hydrolases family 18
HGCPKCDE_02154 3.5e-82 G Glycosyl hydrolases family 18
HGCPKCDE_02155 1.2e-35 3.5.1.104 M LysM domain
HGCPKCDE_02156 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
HGCPKCDE_02157 2.9e-131 IQ Enoyl-(Acyl carrier protein) reductase
HGCPKCDE_02158 9.3e-59 ykvN K HxlR-like helix-turn-helix
HGCPKCDE_02159 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HGCPKCDE_02160 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HGCPKCDE_02161 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HGCPKCDE_02162 6.2e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HGCPKCDE_02163 1.8e-179 ykvI S membrane
HGCPKCDE_02164 0.0 clpE O Belongs to the ClpA ClpB family
HGCPKCDE_02165 1e-137 motA N flagellar motor
HGCPKCDE_02166 2.5e-125 motB N Flagellar motor protein
HGCPKCDE_02167 1.3e-75 ykvE K transcriptional
HGCPKCDE_02168 1.4e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HGCPKCDE_02169 2.6e-63 eag
HGCPKCDE_02170 7.5e-10 S Spo0E like sporulation regulatory protein
HGCPKCDE_02171 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
HGCPKCDE_02172 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HGCPKCDE_02173 8e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HGCPKCDE_02174 7.1e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HGCPKCDE_02175 1.3e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HGCPKCDE_02176 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
HGCPKCDE_02177 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HGCPKCDE_02178 1.2e-227 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HGCPKCDE_02179 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HGCPKCDE_02181 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HGCPKCDE_02182 0.0 kinE 2.7.13.3 T Histidine kinase
HGCPKCDE_02183 1.4e-187 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HGCPKCDE_02184 3.4e-17 ykzE
HGCPKCDE_02185 1.2e-10 ydfR S Protein of unknown function (DUF421)
HGCPKCDE_02186 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HGCPKCDE_02187 3.9e-154 htpX O Belongs to the peptidase M48B family
HGCPKCDE_02188 1.5e-124 ykrK S Domain of unknown function (DUF1836)
HGCPKCDE_02189 1.9e-26 sspD S small acid-soluble spore protein
HGCPKCDE_02190 4.4e-110 rsgI S Anti-sigma factor N-terminus
HGCPKCDE_02191 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCPKCDE_02192 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HGCPKCDE_02193 3.5e-109 ykoX S membrane-associated protein
HGCPKCDE_02194 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HGCPKCDE_02195 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HGCPKCDE_02196 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HGCPKCDE_02197 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HGCPKCDE_02198 0.0 ykoS
HGCPKCDE_02199 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HGCPKCDE_02200 1.1e-98 ykoP G polysaccharide deacetylase
HGCPKCDE_02201 3.6e-218 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HGCPKCDE_02202 1.3e-81 mhqR K transcriptional
HGCPKCDE_02203 6.9e-26 ykoL
HGCPKCDE_02204 5.9e-18
HGCPKCDE_02205 1.4e-53 tnrA K transcriptional
HGCPKCDE_02206 2.2e-222 mgtE P Acts as a magnesium transporter
HGCPKCDE_02209 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
HGCPKCDE_02210 6.2e-112 ykoI S Peptidase propeptide and YPEB domain
HGCPKCDE_02211 8.3e-241 ykoH 2.7.13.3 T Histidine kinase
HGCPKCDE_02212 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCPKCDE_02213 3.3e-109 ykoF S YKOF-related Family
HGCPKCDE_02214 1e-97 ykoE S ABC-type cobalt transport system, permease component
HGCPKCDE_02215 7e-303 P ABC transporter, ATP-binding protein
HGCPKCDE_02216 5.3e-136 ykoC P Cobalt transport protein
HGCPKCDE_02217 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGCPKCDE_02218 5e-176 isp O Belongs to the peptidase S8 family
HGCPKCDE_02219 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HGCPKCDE_02220 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HGCPKCDE_02221 8.4e-72 ohrB O Organic hydroperoxide resistance protein
HGCPKCDE_02222 2.2e-73 ohrR K COG1846 Transcriptional regulators
HGCPKCDE_02223 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HGCPKCDE_02224 9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGCPKCDE_02225 8.8e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGCPKCDE_02226 1.1e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HGCPKCDE_02227 7e-50 ykkD P Multidrug resistance protein
HGCPKCDE_02228 3.5e-55 ykkC P Multidrug resistance protein
HGCPKCDE_02229 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGCPKCDE_02230 7.4e-97 ykkA S Protein of unknown function (DUF664)
HGCPKCDE_02231 2.7e-129 ykjA S Protein of unknown function (DUF421)
HGCPKCDE_02232 1e-07
HGCPKCDE_02233 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HGCPKCDE_02234 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HGCPKCDE_02235 1.2e-160 ykgA E Amidinotransferase
HGCPKCDE_02236 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
HGCPKCDE_02237 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
HGCPKCDE_02238 3.8e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HGCPKCDE_02239 6.3e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HGCPKCDE_02240 4.2e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HGCPKCDE_02242 0.0 dppE E ABC transporter substrate-binding protein
HGCPKCDE_02243 1.3e-187 dppD P Belongs to the ABC transporter superfamily
HGCPKCDE_02244 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGCPKCDE_02245 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGCPKCDE_02246 5.1e-153 dppA E D-aminopeptidase
HGCPKCDE_02247 2.4e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HGCPKCDE_02248 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGCPKCDE_02250 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HGCPKCDE_02251 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGCPKCDE_02252 1.8e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HGCPKCDE_02253 2.3e-240 steT E amino acid
HGCPKCDE_02254 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HGCPKCDE_02255 5.8e-175 pit P phosphate transporter
HGCPKCDE_02256 1.5e-135 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HGCPKCDE_02257 6.7e-23 spoIISB S Stage II sporulation protein SB
HGCPKCDE_02258 3.8e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HGCPKCDE_02259 3e-38 xhlB S SPP1 phage holin
HGCPKCDE_02260 2.8e-39 xhlA S Haemolysin XhlA
HGCPKCDE_02261 4.4e-152 xepA
HGCPKCDE_02262 9.3e-22 xkdX
HGCPKCDE_02263 2.7e-44 xkdW S XkdW protein
HGCPKCDE_02264 1.5e-179
HGCPKCDE_02265 6.7e-41
HGCPKCDE_02266 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HGCPKCDE_02267 1.8e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HGCPKCDE_02268 1.1e-69 xkdS S Protein of unknown function (DUF2634)
HGCPKCDE_02269 2.1e-39 xkdR S Protein of unknown function (DUF2577)
HGCPKCDE_02270 1.3e-179 yqbQ 3.2.1.96 G NLP P60 protein
HGCPKCDE_02271 2.7e-118 xkdP S Lysin motif
HGCPKCDE_02272 1.5e-271 xkdO L Transglycosylase SLT domain
HGCPKCDE_02273 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
HGCPKCDE_02274 6.1e-76 xkdM S Phage tail tube protein
HGCPKCDE_02275 2.1e-255 xkdK S Phage tail sheath C-terminal domain
HGCPKCDE_02276 1.2e-76 xkdJ
HGCPKCDE_02277 8.4e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
HGCPKCDE_02278 1.6e-63 yqbH S Domain of unknown function (DUF3599)
HGCPKCDE_02279 5.1e-63 yqbG S Protein of unknown function (DUF3199)
HGCPKCDE_02280 5.8e-169 xkdG S Phage capsid family
HGCPKCDE_02281 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HGCPKCDE_02282 5.4e-286 yqbA S portal protein
HGCPKCDE_02283 2.8e-254 xtmB S phage terminase, large subunit
HGCPKCDE_02284 4.8e-140 xtmA L phage terminase small subunit
HGCPKCDE_02285 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HGCPKCDE_02286 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HGCPKCDE_02289 6.4e-119 xkdC L Bacterial dnaA protein
HGCPKCDE_02290 5.9e-157 xkdB K sequence-specific DNA binding
HGCPKCDE_02292 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HGCPKCDE_02293 1.6e-111 xkdA E IrrE N-terminal-like domain
HGCPKCDE_02294 9.8e-160 ydbD P Catalase
HGCPKCDE_02295 7.9e-111 yjqB S Pfam:DUF867
HGCPKCDE_02296 4.4e-59 yjqA S Bacterial PH domain
HGCPKCDE_02297 4e-165 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HGCPKCDE_02298 5.3e-40 S YCII-related domain
HGCPKCDE_02300 1e-212 S response regulator aspartate phosphatase
HGCPKCDE_02301 1e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HGCPKCDE_02302 2.3e-78 yjoA S DinB family
HGCPKCDE_02303 2.2e-129 MA20_18170 S membrane transporter protein
HGCPKCDE_02304 7.1e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HGCPKCDE_02305 1.1e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HGCPKCDE_02306 3.1e-184 exuR K transcriptional
HGCPKCDE_02307 5.4e-226 exuT G Sugar (and other) transporter
HGCPKCDE_02308 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCPKCDE_02309 2.6e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HGCPKCDE_02310 3.1e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HGCPKCDE_02311 7.1e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HGCPKCDE_02312 3.7e-249 yjmB G symporter YjmB
HGCPKCDE_02313 5.1e-278 uxaC 5.3.1.12 G glucuronate isomerase
HGCPKCDE_02314 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
HGCPKCDE_02315 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HGCPKCDE_02316 6.4e-90 yjlB S Cupin domain
HGCPKCDE_02317 2.3e-176 yjlA EG Putative multidrug resistance efflux transporter
HGCPKCDE_02318 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HGCPKCDE_02319 5.6e-122 ybbM S transport system, permease component
HGCPKCDE_02320 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HGCPKCDE_02321 8.2e-30
HGCPKCDE_02322 7.2e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HGCPKCDE_02323 1.8e-220 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HGCPKCDE_02325 1.9e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HGCPKCDE_02326 8.7e-07 S Domain of unknown function (DUF4352)
HGCPKCDE_02327 5.7e-95 yjgD S Protein of unknown function (DUF1641)
HGCPKCDE_02328 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HGCPKCDE_02329 2e-103 yjgB S Domain of unknown function (DUF4309)
HGCPKCDE_02330 6e-45 T PhoQ Sensor
HGCPKCDE_02331 1.1e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
HGCPKCDE_02332 2.3e-20 yjfB S Putative motility protein
HGCPKCDE_02333 8.8e-81 S Protein of unknown function (DUF2690)
HGCPKCDE_02334 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
HGCPKCDE_02336 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HGCPKCDE_02337 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
HGCPKCDE_02338 7.1e-29 S Domain of unknown function (DUF4177)
HGCPKCDE_02339 2.6e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HGCPKCDE_02341 3.4e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HGCPKCDE_02342 4.1e-50 yjdF S Protein of unknown function (DUF2992)
HGCPKCDE_02343 3.3e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HGCPKCDE_02344 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HGCPKCDE_02345 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HGCPKCDE_02347 7.8e-140 IQ Enoyl-(Acyl carrier protein) reductase
HGCPKCDE_02348 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
HGCPKCDE_02349 2.8e-173 S response regulator aspartate phosphatase
HGCPKCDE_02352 7.5e-22
HGCPKCDE_02353 4.3e-248 M nucleic acid phosphodiester bond hydrolysis
HGCPKCDE_02354 1.1e-30
HGCPKCDE_02355 1.6e-38
HGCPKCDE_02356 3.4e-10
HGCPKCDE_02358 2.1e-208 yjcL S Protein of unknown function (DUF819)
HGCPKCDE_02359 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
HGCPKCDE_02360 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HGCPKCDE_02361 8.6e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HGCPKCDE_02362 1e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
HGCPKCDE_02363 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HGCPKCDE_02364 8.7e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCPKCDE_02365 1.7e-38
HGCPKCDE_02366 0.0 yjcD 3.6.4.12 L DNA helicase
HGCPKCDE_02367 2.9e-38 spoVIF S Stage VI sporulation protein F
HGCPKCDE_02370 5.6e-56 yjcA S Protein of unknown function (DUF1360)
HGCPKCDE_02371 3.2e-49 cotV S Spore Coat Protein X and V domain
HGCPKCDE_02372 7.4e-23 cotW
HGCPKCDE_02373 1.2e-67 cotX S Spore Coat Protein X and V domain
HGCPKCDE_02374 7.6e-96 cotY S Spore coat protein Z
HGCPKCDE_02375 4.4e-82 cotZ S Spore coat protein
HGCPKCDE_02376 5.9e-54 yjbX S Spore coat protein
HGCPKCDE_02377 5.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HGCPKCDE_02378 6.9e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HGCPKCDE_02379 6.7e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HGCPKCDE_02380 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HGCPKCDE_02381 2.6e-29 thiS H thiamine diphosphate biosynthetic process
HGCPKCDE_02382 4.9e-215 thiO 1.4.3.19 E Glycine oxidase
HGCPKCDE_02383 4.6e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HGCPKCDE_02384 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HGCPKCDE_02385 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HGCPKCDE_02386 4.3e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HGCPKCDE_02387 4e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGCPKCDE_02388 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGCPKCDE_02389 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HGCPKCDE_02390 7.1e-62 yjbL S Belongs to the UPF0738 family
HGCPKCDE_02391 1e-99 yjbK S protein conserved in bacteria
HGCPKCDE_02392 6.1e-89 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HGCPKCDE_02393 3.7e-72 yjbI S Bacterial-like globin
HGCPKCDE_02394 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HGCPKCDE_02395 1.8e-20
HGCPKCDE_02396 0.0 pepF E oligoendopeptidase F
HGCPKCDE_02397 5e-215 yjbF S Competence protein
HGCPKCDE_02398 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HGCPKCDE_02399 6e-112 yjbE P Integral membrane protein TerC family
HGCPKCDE_02400 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HGCPKCDE_02401 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCPKCDE_02402 2.2e-205 yjbB EGP Major Facilitator Superfamily
HGCPKCDE_02403 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HGCPKCDE_02404 6.8e-198 oppD P Belongs to the ABC transporter superfamily
HGCPKCDE_02405 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGCPKCDE_02406 7.8e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGCPKCDE_02407 0.0 oppA E ABC transporter substrate-binding protein
HGCPKCDE_02408 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HGCPKCDE_02409 1.9e-146 yjbA S Belongs to the UPF0736 family
HGCPKCDE_02410 2.3e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGCPKCDE_02411 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGCPKCDE_02412 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HGCPKCDE_02413 4.2e-186 appF E Belongs to the ABC transporter superfamily
HGCPKCDE_02414 1.8e-184 appD P Belongs to the ABC transporter superfamily
HGCPKCDE_02415 1.9e-149 yjaZ O Zn-dependent protease
HGCPKCDE_02416 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HGCPKCDE_02417 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGCPKCDE_02418 2.7e-22 yjzB
HGCPKCDE_02419 7.3e-26 comZ S ComZ
HGCPKCDE_02420 2.5e-183 med S Transcriptional activator protein med
HGCPKCDE_02421 9e-101 yjaV
HGCPKCDE_02422 1.1e-141 yjaU I carboxylic ester hydrolase activity
HGCPKCDE_02423 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HGCPKCDE_02424 9.5e-28 yjzC S YjzC-like protein
HGCPKCDE_02425 8.6e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGCPKCDE_02426 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HGCPKCDE_02427 4.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HGCPKCDE_02428 1.9e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HGCPKCDE_02429 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HGCPKCDE_02430 3.4e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HGCPKCDE_02431 1.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HGCPKCDE_02432 1.7e-88 norB G Major Facilitator Superfamily
HGCPKCDE_02433 2.4e-267 yitY C D-arabinono-1,4-lactone oxidase
HGCPKCDE_02434 1.5e-22 pilT S Proteolipid membrane potential modulator
HGCPKCDE_02435 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HGCPKCDE_02436 1.7e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HGCPKCDE_02437 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HGCPKCDE_02439 2.8e-17 S Protein of unknown function (DUF3813)
HGCPKCDE_02440 5e-73 ipi S Intracellular proteinase inhibitor
HGCPKCDE_02441 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HGCPKCDE_02442 1.3e-156 yitS S protein conserved in bacteria
HGCPKCDE_02443 6.7e-311 nprB 3.4.24.28 E Peptidase M4
HGCPKCDE_02444 1.4e-44 yitR S Domain of unknown function (DUF3784)
HGCPKCDE_02445 2.9e-94
HGCPKCDE_02446 1.5e-58 K Transcriptional regulator PadR-like family
HGCPKCDE_02447 7.6e-97 S Sporulation delaying protein SdpA
HGCPKCDE_02448 1.4e-170
HGCPKCDE_02449 8.5e-94
HGCPKCDE_02450 6.9e-161 cvfB S protein conserved in bacteria
HGCPKCDE_02451 4.3e-54 yajQ S Belongs to the UPF0234 family
HGCPKCDE_02452 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HGCPKCDE_02453 1.3e-81 yjcF S Acetyltransferase (GNAT) domain
HGCPKCDE_02454 1.9e-158 yitH K Acetyltransferase (GNAT) domain
HGCPKCDE_02455 7.5e-228 yitG EGP Major facilitator Superfamily
HGCPKCDE_02456 1.7e-220 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HGCPKCDE_02457 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HGCPKCDE_02458 1.9e-141 yitD 4.4.1.19 S synthase
HGCPKCDE_02459 5.6e-121 comB 3.1.3.71 H Belongs to the ComB family
HGCPKCDE_02460 2.1e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HGCPKCDE_02461 7.9e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HGCPKCDE_02462 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HGCPKCDE_02463 4.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HGCPKCDE_02464 2e-35 mcbG S Pentapeptide repeats (9 copies)
HGCPKCDE_02465 5.5e-155 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCPKCDE_02466 1.7e-108 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCPKCDE_02467 1.9e-107 argO S Lysine exporter protein LysE YggA
HGCPKCDE_02468 1.8e-92 yisT S DinB family
HGCPKCDE_02469 2.5e-197 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HGCPKCDE_02470 1.5e-183 purR K helix_turn _helix lactose operon repressor
HGCPKCDE_02471 5.9e-160 yisR K Transcriptional regulator
HGCPKCDE_02472 4e-243 yisQ V Mate efflux family protein
HGCPKCDE_02473 2.4e-147 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HGCPKCDE_02474 4.7e-88 yizA S Damage-inducible protein DinB
HGCPKCDE_02475 0.0 asnO 6.3.5.4 E Asparagine synthase
HGCPKCDE_02476 4.8e-102 yisN S Protein of unknown function (DUF2777)
HGCPKCDE_02477 0.0 wprA O Belongs to the peptidase S8 family
HGCPKCDE_02478 6.6e-57 yisL S UPF0344 protein
HGCPKCDE_02479 5.4e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HGCPKCDE_02480 3.1e-175 cotH M Spore Coat
HGCPKCDE_02481 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HGCPKCDE_02482 1.9e-33 gerPA S Spore germination protein
HGCPKCDE_02483 4e-34 gerPB S cell differentiation
HGCPKCDE_02484 1.8e-54 gerPC S Spore germination protein
HGCPKCDE_02485 6.3e-24 gerPD S Spore germination protein
HGCPKCDE_02486 3e-66 gerPE S Spore germination protein GerPE
HGCPKCDE_02487 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HGCPKCDE_02488 6.7e-50 yisB V COG1403 Restriction endonuclease
HGCPKCDE_02489 0.0 sbcC L COG0419 ATPase involved in DNA repair
HGCPKCDE_02490 1.3e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HGCPKCDE_02491 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HGCPKCDE_02492 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HGCPKCDE_02493 2.2e-78 yhjR S Rubrerythrin
HGCPKCDE_02494 1.6e-36 yhjQ C COG1145 Ferredoxin
HGCPKCDE_02495 0.0 S Sugar transport-related sRNA regulator N-term
HGCPKCDE_02496 9e-215 EGP Transmembrane secretion effector
HGCPKCDE_02497 1.9e-201 abrB S membrane
HGCPKCDE_02498 2.2e-187 yhjM 5.1.1.1 K Transcriptional regulator
HGCPKCDE_02499 2.4e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HGCPKCDE_02500 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HGCPKCDE_02501 1.6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HGCPKCDE_02502 1.7e-213 glcP G Major Facilitator Superfamily
HGCPKCDE_02503 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HGCPKCDE_02504 2e-280 yhjG CH FAD binding domain
HGCPKCDE_02505 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HGCPKCDE_02506 9.1e-110 yhjE S SNARE associated Golgi protein
HGCPKCDE_02507 6.7e-60 yhjD
HGCPKCDE_02508 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HGCPKCDE_02509 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGCPKCDE_02510 1.1e-40 yhjA S Excalibur calcium-binding domain
HGCPKCDE_02511 1.4e-164 IQ Enoyl-(Acyl carrier protein) reductase
HGCPKCDE_02512 9.3e-109 comK K Competence transcription factor
HGCPKCDE_02513 1.3e-32 yhzC S IDEAL
HGCPKCDE_02514 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCPKCDE_02515 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HGCPKCDE_02516 1.7e-182 hemAT NT chemotaxis protein
HGCPKCDE_02517 5e-91 bioY S BioY family
HGCPKCDE_02518 1.9e-275 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HGCPKCDE_02519 1.1e-195 vraB 2.3.1.9 I Belongs to the thiolase family
HGCPKCDE_02520 7.1e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HGCPKCDE_02521 4.9e-155 yfmC M Periplasmic binding protein
HGCPKCDE_02522 3.1e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
HGCPKCDE_02523 4.7e-76 VY92_01935 K acetyltransferase
HGCPKCDE_02524 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HGCPKCDE_02525 4.6e-241 yhfN 3.4.24.84 O Peptidase M48
HGCPKCDE_02526 1.9e-65 yhfM
HGCPKCDE_02527 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HGCPKCDE_02528 7.7e-112 yhfK GM NmrA-like family
HGCPKCDE_02529 4.9e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
HGCPKCDE_02530 4e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HGCPKCDE_02531 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGCPKCDE_02532 3.2e-71 3.4.13.21 S ASCH
HGCPKCDE_02533 3.5e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HGCPKCDE_02534 2.2e-137 yhfC S Putative membrane peptidase family (DUF2324)
HGCPKCDE_02535 8.1e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGCPKCDE_02536 1.3e-225 yhgE S YhgE Pip N-terminal domain protein
HGCPKCDE_02537 5.4e-101 yhgD K Transcriptional regulator
HGCPKCDE_02538 5.9e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HGCPKCDE_02539 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HGCPKCDE_02540 6.5e-201 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HGCPKCDE_02541 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HGCPKCDE_02542 6.4e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HGCPKCDE_02543 1.2e-32 1.15.1.2 C Rubrerythrin
HGCPKCDE_02544 1.1e-245 yhfA C membrane
HGCPKCDE_02545 9.2e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HGCPKCDE_02546 3.1e-114 ecsC S EcsC protein family
HGCPKCDE_02547 2e-214 ecsB U ABC transporter
HGCPKCDE_02548 4.6e-137 ecsA V transporter (ATP-binding protein)
HGCPKCDE_02549 1.8e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HGCPKCDE_02550 7.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HGCPKCDE_02551 3.6e-80 trpP S Tryptophan transporter TrpP
HGCPKCDE_02552 5.4e-21
HGCPKCDE_02553 7e-39 yhaH S YtxH-like protein
HGCPKCDE_02554 1e-113 hpr K Negative regulator of protease production and sporulation
HGCPKCDE_02555 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HGCPKCDE_02556 8.7e-90 yhaK S Putative zincin peptidase
HGCPKCDE_02557 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HGCPKCDE_02558 1.6e-21 yhaL S Sporulation protein YhaL
HGCPKCDE_02559 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HGCPKCDE_02560 0.0 yhaN L AAA domain
HGCPKCDE_02561 3.7e-224 yhaO L DNA repair exonuclease
HGCPKCDE_02562 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HGCPKCDE_02563 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HGCPKCDE_02564 1.1e-26 S YhzD-like protein
HGCPKCDE_02565 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
HGCPKCDE_02567 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HGCPKCDE_02568 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HGCPKCDE_02569 1.8e-292 hemZ H coproporphyrinogen III oxidase
HGCPKCDE_02570 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HGCPKCDE_02571 8.6e-201 yhaZ L DNA alkylation repair enzyme
HGCPKCDE_02572 9.5e-48 yheA S Belongs to the UPF0342 family
HGCPKCDE_02573 1.4e-201 yheB S Belongs to the UPF0754 family
HGCPKCDE_02574 7.4e-216 yheC HJ YheC/D like ATP-grasp
HGCPKCDE_02575 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HGCPKCDE_02576 1.3e-36 yheE S Family of unknown function (DUF5342)
HGCPKCDE_02577 6.3e-28 sspB S spore protein
HGCPKCDE_02578 3.7e-111 yheG GM NAD(P)H-binding
HGCPKCDE_02579 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HGCPKCDE_02580 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HGCPKCDE_02581 1.7e-83 nhaX T Belongs to the universal stress protein A family
HGCPKCDE_02582 1e-230 nhaC C Na H antiporter
HGCPKCDE_02583 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HGCPKCDE_02584 1.6e-149 yheN G deacetylase
HGCPKCDE_02585 5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HGCPKCDE_02586 9.9e-184 yhdY M Mechanosensitive ion channel
HGCPKCDE_02588 1.5e-132 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HGCPKCDE_02589 2.5e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGCPKCDE_02590 4.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGCPKCDE_02591 4.2e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HGCPKCDE_02592 3.3e-222 yhdR 2.6.1.1 E Aminotransferase
HGCPKCDE_02593 4.1e-74 cueR K transcriptional
HGCPKCDE_02594 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HGCPKCDE_02595 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HGCPKCDE_02596 3.4e-191 yhdN C Aldo keto reductase
HGCPKCDE_02597 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HGCPKCDE_02598 6.6e-201 yhdL S Sigma factor regulator N-terminal
HGCPKCDE_02599 8.1e-45 yhdK S Sigma-M inhibitor protein
HGCPKCDE_02600 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCPKCDE_02601 2.1e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGCPKCDE_02602 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HGCPKCDE_02603 3.4e-250 yhdG E amino acid
HGCPKCDE_02604 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCPKCDE_02605 1.2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
HGCPKCDE_02606 8.4e-162 citR K Transcriptional regulator
HGCPKCDE_02607 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HGCPKCDE_02608 2.5e-253 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HGCPKCDE_02609 2.1e-276 ycgB S Stage V sporulation protein R
HGCPKCDE_02610 1.5e-238 ygxB M Conserved TM helix
HGCPKCDE_02611 1e-75 nsrR K Transcriptional regulator
HGCPKCDE_02612 1.6e-186 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HGCPKCDE_02613 4.8e-54 yhdC S Protein of unknown function (DUF3889)
HGCPKCDE_02614 1.2e-38 yhdB S YhdB-like protein
HGCPKCDE_02615 2.5e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
HGCPKCDE_02616 1e-108 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCPKCDE_02617 4.7e-213 yhcY 2.7.13.3 T Histidine kinase
HGCPKCDE_02618 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HGCPKCDE_02619 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HGCPKCDE_02620 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HGCPKCDE_02621 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HGCPKCDE_02622 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HGCPKCDE_02623 7.8e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGCPKCDE_02624 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HGCPKCDE_02625 4.6e-120 yhcW 5.4.2.6 S hydrolase
HGCPKCDE_02626 9.9e-68 yhcV S COG0517 FOG CBS domain
HGCPKCDE_02627 9.3e-68 yhcU S Family of unknown function (DUF5365)
HGCPKCDE_02628 4.8e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGCPKCDE_02629 3.5e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HGCPKCDE_02630 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HGCPKCDE_02631 5.2e-100 yhcQ M Spore coat protein
HGCPKCDE_02632 1.1e-165 yhcP
HGCPKCDE_02633 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGCPKCDE_02634 3.2e-40 yhcM
HGCPKCDE_02635 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGCPKCDE_02636 1.3e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HGCPKCDE_02637 9.1e-150 metQ M Belongs to the nlpA lipoprotein family
HGCPKCDE_02638 1e-30 cspB K Cold-shock protein
HGCPKCDE_02639 5.6e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HGCPKCDE_02640 2.2e-165 yhcH V ABC transporter, ATP-binding protein
HGCPKCDE_02641 4e-122 yhcG V ABC transporter, ATP-binding protein
HGCPKCDE_02642 6.6e-60 yhcF K Transcriptional regulator
HGCPKCDE_02643 2e-55
HGCPKCDE_02644 2.8e-37 yhcC
HGCPKCDE_02645 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HGCPKCDE_02646 3.1e-271 yhcA EGP Major facilitator Superfamily
HGCPKCDE_02647 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HGCPKCDE_02648 2.2e-76 yhbI K DNA-binding transcription factor activity
HGCPKCDE_02649 2.5e-225 yhbH S Belongs to the UPF0229 family
HGCPKCDE_02650 0.0 prkA T Ser protein kinase
HGCPKCDE_02651 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HGCPKCDE_02652 4.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HGCPKCDE_02653 1.2e-109 yhbD K Protein of unknown function (DUF4004)
HGCPKCDE_02654 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HGCPKCDE_02655 2.4e-175 yhbB S Putative amidase domain
HGCPKCDE_02656 2.3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HGCPKCDE_02657 7.9e-114 yhzB S B3/4 domain
HGCPKCDE_02659 4.4e-29 K Transcriptional regulator
HGCPKCDE_02660 4.1e-78 ygaO
HGCPKCDE_02661 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGCPKCDE_02663 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HGCPKCDE_02664 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HGCPKCDE_02665 4e-168 ssuA M Sulfonate ABC transporter
HGCPKCDE_02666 3.7e-137 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HGCPKCDE_02667 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HGCPKCDE_02669 1.5e-263 ygaK C Berberine and berberine like
HGCPKCDE_02670 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HGCPKCDE_02671 2.9e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HGCPKCDE_02672 1.2e-26
HGCPKCDE_02673 2.7e-143 spo0M S COG4326 Sporulation control protein
HGCPKCDE_02677 2e-08
HGCPKCDE_02685 7.8e-08
HGCPKCDE_02692 3.4e-39 S COG NOG14552 non supervised orthologous group
HGCPKCDE_02693 1.3e-89 thiT S Thiamine transporter protein (Thia_YuaJ)
HGCPKCDE_02694 3.8e-93 M1-753 M FR47-like protein
HGCPKCDE_02695 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
HGCPKCDE_02696 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HGCPKCDE_02697 3.9e-84 yuaE S DinB superfamily
HGCPKCDE_02698 6.7e-107 yuaD
HGCPKCDE_02699 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HGCPKCDE_02700 6.8e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HGCPKCDE_02701 5.5e-95 yuaC K Belongs to the GbsR family
HGCPKCDE_02702 2.2e-91 yuaB
HGCPKCDE_02703 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
HGCPKCDE_02704 1.6e-236 ktrB P Potassium
HGCPKCDE_02705 1e-38 yiaA S yiaA/B two helix domain
HGCPKCDE_02706 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGCPKCDE_02707 1.2e-272 yubD P Major Facilitator Superfamily
HGCPKCDE_02708 5.4e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HGCPKCDE_02710 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HGCPKCDE_02711 2e-195 yubA S transporter activity
HGCPKCDE_02712 3.3e-183 ygjR S Oxidoreductase
HGCPKCDE_02713 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HGCPKCDE_02714 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HGCPKCDE_02715 1.4e-275 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HGCPKCDE_02716 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HGCPKCDE_02717 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HGCPKCDE_02718 7.3e-238 mcpA NT chemotaxis protein
HGCPKCDE_02719 5.5e-294 mcpA NT chemotaxis protein
HGCPKCDE_02720 2.4e-220 mcpA NT chemotaxis protein
HGCPKCDE_02721 3.2e-225 mcpA NT chemotaxis protein
HGCPKCDE_02722 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HGCPKCDE_02723 2.3e-35
HGCPKCDE_02724 2.1e-72 yugU S Uncharacterised protein family UPF0047
HGCPKCDE_02725 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HGCPKCDE_02726 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HGCPKCDE_02727 1.4e-116 yugP S Zn-dependent protease
HGCPKCDE_02728 2.3e-38
HGCPKCDE_02729 1.1e-53 mstX S Membrane-integrating protein Mistic
HGCPKCDE_02730 8.2e-182 yugO P COG1226 Kef-type K transport systems
HGCPKCDE_02731 2.8e-72 yugN S YugN-like family
HGCPKCDE_02733 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HGCPKCDE_02734 1.8e-228 yugK C Dehydrogenase
HGCPKCDE_02735 5.8e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HGCPKCDE_02736 1.1e-34 yuzA S Domain of unknown function (DUF378)
HGCPKCDE_02737 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HGCPKCDE_02738 2.1e-199 yugH 2.6.1.1 E Aminotransferase
HGCPKCDE_02739 1.6e-85 alaR K Transcriptional regulator
HGCPKCDE_02740 1.1e-155 yugF I Hydrolase
HGCPKCDE_02741 7.8e-39 yugE S Domain of unknown function (DUF1871)
HGCPKCDE_02742 2.6e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HGCPKCDE_02743 4.6e-233 T PhoQ Sensor
HGCPKCDE_02744 1.8e-68 kapB G Kinase associated protein B
HGCPKCDE_02745 1.9e-115 kapD L the KinA pathway to sporulation
HGCPKCDE_02747 2.1e-183 yuxJ EGP Major facilitator Superfamily
HGCPKCDE_02748 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HGCPKCDE_02749 6.3e-75 yuxK S protein conserved in bacteria
HGCPKCDE_02750 6.3e-78 yufK S Family of unknown function (DUF5366)
HGCPKCDE_02751 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HGCPKCDE_02752 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HGCPKCDE_02753 1.3e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HGCPKCDE_02754 1.6e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HGCPKCDE_02755 1.4e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HGCPKCDE_02756 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HGCPKCDE_02757 8.2e-233 maeN C COG3493 Na citrate symporter
HGCPKCDE_02758 5e-15
HGCPKCDE_02759 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HGCPKCDE_02760 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGCPKCDE_02761 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGCPKCDE_02762 3.2e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGCPKCDE_02763 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGCPKCDE_02764 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGCPKCDE_02765 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HGCPKCDE_02766 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HGCPKCDE_02767 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCPKCDE_02768 0.0 comP 2.7.13.3 T Histidine kinase
HGCPKCDE_02770 3.2e-162 comQ H Polyprenyl synthetase
HGCPKCDE_02772 1.1e-22 yuzC
HGCPKCDE_02773 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HGCPKCDE_02775 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGCPKCDE_02776 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
HGCPKCDE_02777 7.9e-67 yueI S Protein of unknown function (DUF1694)
HGCPKCDE_02778 1.4e-37 yueH S YueH-like protein
HGCPKCDE_02779 1.7e-31 yueG S Spore germination protein gerPA/gerPF
HGCPKCDE_02780 3.2e-190 yueF S transporter activity
HGCPKCDE_02781 4.4e-70 S Protein of unknown function (DUF2283)
HGCPKCDE_02782 2.9e-24 S Protein of unknown function (DUF2642)
HGCPKCDE_02783 4.8e-96 yueE S phosphohydrolase
HGCPKCDE_02784 4.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCPKCDE_02785 3.3e-64 yueC S Family of unknown function (DUF5383)
HGCPKCDE_02786 0.0 esaA S type VII secretion protein EsaA
HGCPKCDE_02787 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HGCPKCDE_02788 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
HGCPKCDE_02789 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HGCPKCDE_02790 2.8e-45 esxA S Belongs to the WXG100 family
HGCPKCDE_02791 5.5e-228 yukF QT Transcriptional regulator
HGCPKCDE_02792 3.6e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HGCPKCDE_02793 1.2e-131 yukJ S Uncharacterized conserved protein (DUF2278)
HGCPKCDE_02794 5e-36 mbtH S MbtH-like protein
HGCPKCDE_02795 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCPKCDE_02796 3.1e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HGCPKCDE_02797 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HGCPKCDE_02798 3.3e-225 entC 5.4.4.2 HQ Isochorismate synthase
HGCPKCDE_02799 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCPKCDE_02800 1.9e-166 besA S Putative esterase
HGCPKCDE_02801 3.7e-121 yuiH S Oxidoreductase molybdopterin binding domain
HGCPKCDE_02802 3.3e-93 bioY S Biotin biosynthesis protein
HGCPKCDE_02803 3.9e-211 yuiF S antiporter
HGCPKCDE_02804 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HGCPKCDE_02805 1.2e-77 yuiD S protein conserved in bacteria
HGCPKCDE_02806 4.7e-117 yuiC S protein conserved in bacteria
HGCPKCDE_02807 1.9e-26 yuiB S Putative membrane protein
HGCPKCDE_02808 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
HGCPKCDE_02809 1.7e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
HGCPKCDE_02811 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGCPKCDE_02812 7.2e-115 paiB K Putative FMN-binding domain
HGCPKCDE_02813 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCPKCDE_02814 3.7e-63 erpA S Belongs to the HesB IscA family
HGCPKCDE_02815 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HGCPKCDE_02816 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGCPKCDE_02817 3.2e-39 yuzB S Belongs to the UPF0349 family
HGCPKCDE_02818 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HGCPKCDE_02819 7.4e-55 yuzD S protein conserved in bacteria
HGCPKCDE_02820 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HGCPKCDE_02821 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HGCPKCDE_02822 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HGCPKCDE_02823 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HGCPKCDE_02824 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
HGCPKCDE_02825 2e-199 yutH S Spore coat protein
HGCPKCDE_02826 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HGCPKCDE_02827 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HGCPKCDE_02828 1e-75 yutE S Protein of unknown function DUF86
HGCPKCDE_02829 9.7e-48 yutD S protein conserved in bacteria
HGCPKCDE_02830 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGCPKCDE_02831 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HGCPKCDE_02832 4.5e-196 lytH M Peptidase, M23
HGCPKCDE_02833 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
HGCPKCDE_02834 3.1e-47 yunC S Domain of unknown function (DUF1805)
HGCPKCDE_02835 1.6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HGCPKCDE_02836 2e-141 yunE S membrane transporter protein
HGCPKCDE_02837 4.3e-171 yunF S Protein of unknown function DUF72
HGCPKCDE_02838 2.8e-60 yunG
HGCPKCDE_02839 3.6e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HGCPKCDE_02840 2.2e-301 pucR QT COG2508 Regulator of polyketide synthase expression
HGCPKCDE_02841 3e-235 pbuX F Permease family
HGCPKCDE_02842 1.3e-222 pbuX F xanthine
HGCPKCDE_02843 2.4e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HGCPKCDE_02844 1.7e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HGCPKCDE_02845 8.1e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HGCPKCDE_02846 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HGCPKCDE_02847 1.3e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HGCPKCDE_02848 1.2e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HGCPKCDE_02849 3e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HGCPKCDE_02851 7.1e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HGCPKCDE_02852 8.3e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HGCPKCDE_02853 1.2e-168 bsn L Ribonuclease
HGCPKCDE_02854 1.3e-204 msmX P Belongs to the ABC transporter superfamily
HGCPKCDE_02855 3.3e-135 yurK K UTRA
HGCPKCDE_02856 5.7e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HGCPKCDE_02857 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
HGCPKCDE_02858 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
HGCPKCDE_02859 1.5e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HGCPKCDE_02860 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HGCPKCDE_02861 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HGCPKCDE_02862 7.1e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HGCPKCDE_02864 1e-41
HGCPKCDE_02865 3.5e-271 sufB O FeS cluster assembly
HGCPKCDE_02866 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HGCPKCDE_02867 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGCPKCDE_02868 1.4e-245 sufD O assembly protein SufD
HGCPKCDE_02869 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HGCPKCDE_02870 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HGCPKCDE_02871 1.6e-146 metQ P Belongs to the NlpA lipoprotein family
HGCPKCDE_02872 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HGCPKCDE_02873 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGCPKCDE_02874 3.2e-56 yusD S SCP-2 sterol transfer family
HGCPKCDE_02875 5.6e-55 traF CO Thioredoxin
HGCPKCDE_02876 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HGCPKCDE_02877 1.1e-39 yusG S Protein of unknown function (DUF2553)
HGCPKCDE_02878 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HGCPKCDE_02879 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HGCPKCDE_02880 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HGCPKCDE_02881 3.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HGCPKCDE_02882 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HGCPKCDE_02883 4.7e-09 S YuzL-like protein
HGCPKCDE_02884 3.8e-165 fadM E Proline dehydrogenase
HGCPKCDE_02885 5.1e-40
HGCPKCDE_02886 9.3e-53 yusN M Coat F domain
HGCPKCDE_02887 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
HGCPKCDE_02888 8.5e-293 yusP P Major facilitator superfamily
HGCPKCDE_02889 7.1e-65 yusQ S Tautomerase enzyme
HGCPKCDE_02890 1.3e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCPKCDE_02891 2.6e-158 yusT K LysR substrate binding domain
HGCPKCDE_02892 3.8e-47 yusU S Protein of unknown function (DUF2573)
HGCPKCDE_02893 1e-153 yusV 3.6.3.34 HP ABC transporter
HGCPKCDE_02894 5.6e-66 S YusW-like protein
HGCPKCDE_02895 3.2e-301 pepF2 E COG1164 Oligoendopeptidase F
HGCPKCDE_02896 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCPKCDE_02897 1.2e-79 dps P Ferritin-like domain
HGCPKCDE_02898 2.1e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGCPKCDE_02899 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCPKCDE_02900 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
HGCPKCDE_02901 1.3e-157 yuxN K Transcriptional regulator
HGCPKCDE_02902 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HGCPKCDE_02903 2.3e-24 S Protein of unknown function (DUF3970)
HGCPKCDE_02904 1.7e-244 gerAA EG Spore germination protein
HGCPKCDE_02905 3.8e-196 gerAB E Spore germination protein
HGCPKCDE_02906 8.5e-183 gerAC S Spore germination B3/ GerAC like, C-terminal
HGCPKCDE_02907 3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCPKCDE_02908 1.6e-186 vraS 2.7.13.3 T Histidine kinase
HGCPKCDE_02909 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HGCPKCDE_02910 1.1e-118 liaG S Putative adhesin
HGCPKCDE_02911 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HGCPKCDE_02912 5.6e-62 liaI S membrane
HGCPKCDE_02913 2.4e-226 yvqJ EGP Major facilitator Superfamily
HGCPKCDE_02914 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
HGCPKCDE_02915 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HGCPKCDE_02916 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCPKCDE_02917 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HGCPKCDE_02918 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCPKCDE_02919 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HGCPKCDE_02920 0.0 T PhoQ Sensor
HGCPKCDE_02921 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCPKCDE_02922 3.6e-22
HGCPKCDE_02923 1.6e-97 yvrI K RNA polymerase
HGCPKCDE_02924 4e-19 S YvrJ protein family
HGCPKCDE_02925 1.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
HGCPKCDE_02926 1.3e-64 yvrL S Regulatory protein YrvL
HGCPKCDE_02927 4e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HGCPKCDE_02928 1.6e-123 macB V ABC transporter, ATP-binding protein
HGCPKCDE_02929 4.8e-176 M Efflux transporter rnd family, mfp subunit
HGCPKCDE_02930 1.3e-148 fhuC 3.6.3.34 HP ABC transporter
HGCPKCDE_02931 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCPKCDE_02932 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGCPKCDE_02933 5.3e-178 fhuD P ABC transporter
HGCPKCDE_02934 4.9e-236 yvsH E Arginine ornithine antiporter
HGCPKCDE_02935 6.5e-16 S Small spore protein J (Spore_SspJ)
HGCPKCDE_02936 3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HGCPKCDE_02937 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HGCPKCDE_02938 1.7e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HGCPKCDE_02939 5.4e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HGCPKCDE_02940 8.1e-120 modB P COG4149 ABC-type molybdate transport system, permease component
HGCPKCDE_02941 1.1e-155 yvgN S reductase
HGCPKCDE_02942 5.4e-86 yvgO
HGCPKCDE_02943 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HGCPKCDE_02944 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HGCPKCDE_02945 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HGCPKCDE_02946 0.0 helD 3.6.4.12 L DNA helicase
HGCPKCDE_02947 4.1e-107 yvgT S membrane
HGCPKCDE_02948 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
HGCPKCDE_02949 1.6e-104 bdbD O Thioredoxin
HGCPKCDE_02950 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HGCPKCDE_02951 0.0 copA 3.6.3.54 P P-type ATPase
HGCPKCDE_02952 5.9e-29 copZ P Copper resistance protein CopZ
HGCPKCDE_02953 2.2e-48 csoR S transcriptional
HGCPKCDE_02954 4e-195 yvaA 1.1.1.371 S Oxidoreductase
HGCPKCDE_02955 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HGCPKCDE_02956 0.0 yvaC S Fusaric acid resistance protein-like
HGCPKCDE_02957 1.3e-72 yvaD S Family of unknown function (DUF5360)
HGCPKCDE_02958 2.4e-54 yvaE P Small Multidrug Resistance protein
HGCPKCDE_02959 2.7e-97 K Bacterial regulatory proteins, tetR family
HGCPKCDE_02960 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCPKCDE_02962 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HGCPKCDE_02963 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HGCPKCDE_02964 5.6e-143 est 3.1.1.1 S Carboxylesterase
HGCPKCDE_02965 2.4e-23 secG U Preprotein translocase subunit SecG
HGCPKCDE_02966 3.4e-151 yvaM S Serine aminopeptidase, S33
HGCPKCDE_02967 7.5e-36 yvzC K Transcriptional
HGCPKCDE_02968 1.2e-68 K transcriptional
HGCPKCDE_02969 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
HGCPKCDE_02970 2.2e-54 yodB K transcriptional
HGCPKCDE_02971 1.1e-223 NT chemotaxis protein
HGCPKCDE_02972 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HGCPKCDE_02973 3.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HGCPKCDE_02974 7.3e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HGCPKCDE_02975 2e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HGCPKCDE_02976 3.3e-60 yvbF K Belongs to the GbsR family
HGCPKCDE_02977 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HGCPKCDE_02978 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HGCPKCDE_02979 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HGCPKCDE_02980 2e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HGCPKCDE_02981 3.5e-97 yvbF K Belongs to the GbsR family
HGCPKCDE_02982 2.4e-102 yvbG U UPF0056 membrane protein
HGCPKCDE_02983 2.1e-111 yvbH S YvbH-like oligomerisation region
HGCPKCDE_02984 1.8e-122 exoY M Membrane
HGCPKCDE_02985 0.0 tcaA S response to antibiotic
HGCPKCDE_02986 1.3e-81 yvbK 3.1.3.25 K acetyltransferase
HGCPKCDE_02987 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HGCPKCDE_02988 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HGCPKCDE_02989 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGCPKCDE_02990 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HGCPKCDE_02991 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGCPKCDE_02992 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HGCPKCDE_02993 6.2e-252 araE EGP Major facilitator Superfamily
HGCPKCDE_02994 5.5e-203 araR K transcriptional
HGCPKCDE_02995 2.6e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCPKCDE_02996 3.9e-159 yvbU K Transcriptional regulator
HGCPKCDE_02997 7.2e-156 yvbV EG EamA-like transporter family
HGCPKCDE_02998 6.2e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HGCPKCDE_02999 9.5e-197 yvbX S Glycosyl hydrolase
HGCPKCDE_03000 6.7e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HGCPKCDE_03001 3.5e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HGCPKCDE_03002 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HGCPKCDE_03003 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCPKCDE_03004 8.9e-201 desK 2.7.13.3 T Histidine kinase
HGCPKCDE_03005 1.4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
HGCPKCDE_03006 1.7e-157 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HGCPKCDE_03007 2.6e-157 rsbQ S Alpha/beta hydrolase family
HGCPKCDE_03008 7.2e-196 rsbU 3.1.3.3 T response regulator
HGCPKCDE_03009 5.4e-250 galA 3.2.1.89 G arabinogalactan
HGCPKCDE_03010 0.0 lacA 3.2.1.23 G beta-galactosidase
HGCPKCDE_03011 7.2e-150 ganQ P transport
HGCPKCDE_03012 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
HGCPKCDE_03013 1.5e-231 cycB G COG2182 Maltose-binding periplasmic proteins domains
HGCPKCDE_03014 1.8e-184 lacR K Transcriptional regulator
HGCPKCDE_03015 6.6e-112 yvfI K COG2186 Transcriptional regulators
HGCPKCDE_03016 5.7e-308 yvfH C L-lactate permease
HGCPKCDE_03017 5.2e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HGCPKCDE_03018 1e-31 yvfG S YvfG protein
HGCPKCDE_03019 4.1e-186 yvfF GM Exopolysaccharide biosynthesis protein
HGCPKCDE_03020 4.3e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HGCPKCDE_03021 5.3e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HGCPKCDE_03022 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HGCPKCDE_03023 7e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGCPKCDE_03024 5e-190 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HGCPKCDE_03025 4.4e-205 epsI GM pyruvyl transferase
HGCPKCDE_03026 4.4e-194 epsH GT2 S Glycosyltransferase like family 2
HGCPKCDE_03027 1.1e-206 epsG S EpsG family
HGCPKCDE_03028 3.2e-217 epsF GT4 M Glycosyl transferases group 1
HGCPKCDE_03029 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HGCPKCDE_03030 2.9e-223 epsD GT4 M Glycosyl transferase 4-like
HGCPKCDE_03031 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HGCPKCDE_03032 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HGCPKCDE_03033 1.5e-121 ywqC M biosynthesis protein
HGCPKCDE_03034 6.3e-76 slr K transcriptional
HGCPKCDE_03035 5e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HGCPKCDE_03037 5.1e-92 padC Q Phenolic acid decarboxylase
HGCPKCDE_03038 5.8e-74 MA20_18690 S Protein of unknown function (DUF3237)
HGCPKCDE_03039 1.9e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HGCPKCDE_03040 2.1e-260 pbpE V Beta-lactamase
HGCPKCDE_03041 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HGCPKCDE_03042 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HGCPKCDE_03043 1.8e-295 yveA E amino acid
HGCPKCDE_03044 2.6e-106 yvdT K Transcriptional regulator
HGCPKCDE_03045 6.7e-51 ykkC P Small Multidrug Resistance protein
HGCPKCDE_03046 4.1e-50 sugE P Small Multidrug Resistance protein
HGCPKCDE_03047 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
HGCPKCDE_03048 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
HGCPKCDE_03049 2.8e-182 S Patatin-like phospholipase
HGCPKCDE_03051 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HGCPKCDE_03052 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HGCPKCDE_03053 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HGCPKCDE_03054 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HGCPKCDE_03055 1e-154 malA S Protein of unknown function (DUF1189)
HGCPKCDE_03056 3.9e-148 malD P transport
HGCPKCDE_03057 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
HGCPKCDE_03058 4.8e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HGCPKCDE_03059 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HGCPKCDE_03060 8.8e-173 yvdE K Transcriptional regulator
HGCPKCDE_03061 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HGCPKCDE_03062 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HGCPKCDE_03063 2.8e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HGCPKCDE_03064 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HGCPKCDE_03065 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGCPKCDE_03066 0.0 yxdM V ABC transporter (permease)
HGCPKCDE_03067 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HGCPKCDE_03068 9.8e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HGCPKCDE_03069 2.1e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCPKCDE_03070 8.8e-33
HGCPKCDE_03071 5.8e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HGCPKCDE_03072 1.6e-36 crh G Phosphocarrier protein Chr
HGCPKCDE_03073 1.4e-170 whiA K May be required for sporulation
HGCPKCDE_03074 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HGCPKCDE_03075 5.7e-166 rapZ S Displays ATPase and GTPase activities
HGCPKCDE_03076 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HGCPKCDE_03077 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HGCPKCDE_03078 2.8e-98 usp CBM50 M protein conserved in bacteria
HGCPKCDE_03079 1e-276 S COG0457 FOG TPR repeat
HGCPKCDE_03080 0.0 msbA2 3.6.3.44 V ABC transporter
HGCPKCDE_03082 0.0
HGCPKCDE_03083 2.2e-74
HGCPKCDE_03084 2.2e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HGCPKCDE_03085 4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HGCPKCDE_03086 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HGCPKCDE_03087 9.6e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HGCPKCDE_03088 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HGCPKCDE_03089 3.6e-230 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HGCPKCDE_03090 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HGCPKCDE_03091 2.6e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HGCPKCDE_03092 1e-139 yvpB NU protein conserved in bacteria
HGCPKCDE_03093 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HGCPKCDE_03094 8.7e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HGCPKCDE_03095 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HGCPKCDE_03096 4e-162 yvoD P COG0370 Fe2 transport system protein B
HGCPKCDE_03097 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HGCPKCDE_03098 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HGCPKCDE_03099 9.2e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HGCPKCDE_03100 9.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGCPKCDE_03101 1.8e-133 yvoA K transcriptional
HGCPKCDE_03102 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HGCPKCDE_03103 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
HGCPKCDE_03104 4.1e-231 cypX 1.14.15.13 C Cytochrome P450
HGCPKCDE_03105 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HGCPKCDE_03106 2e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
HGCPKCDE_03107 2.7e-203 yvmA EGP Major facilitator Superfamily
HGCPKCDE_03108 1.2e-50 yvlD S Membrane
HGCPKCDE_03109 4.4e-26 pspB KT PspC domain
HGCPKCDE_03110 4.9e-167 yvlB S Putative adhesin
HGCPKCDE_03111 1.8e-48 yvlA
HGCPKCDE_03112 5.7e-33 yvkN
HGCPKCDE_03113 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HGCPKCDE_03114 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HGCPKCDE_03115 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HGCPKCDE_03116 1.2e-30 csbA S protein conserved in bacteria
HGCPKCDE_03117 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HGCPKCDE_03118 1.3e-99 yvkB K Transcriptional regulator
HGCPKCDE_03119 1.6e-225 yvkA EGP Major facilitator Superfamily
HGCPKCDE_03120 3.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGCPKCDE_03121 5.3e-56 swrA S Swarming motility protein
HGCPKCDE_03122 1.5e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HGCPKCDE_03123 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HGCPKCDE_03124 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HGCPKCDE_03125 2e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
HGCPKCDE_03126 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HGCPKCDE_03127 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HGCPKCDE_03128 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HGCPKCDE_03129 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGCPKCDE_03130 2.8e-66
HGCPKCDE_03131 1.9e-08 fliT S bacterial-type flagellum organization
HGCPKCDE_03132 2.9e-69 fliS N flagellar protein FliS
HGCPKCDE_03133 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HGCPKCDE_03134 6.1e-57 flaG N flagellar protein FlaG
HGCPKCDE_03135 9e-81 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HGCPKCDE_03136 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HGCPKCDE_03137 6.3e-70 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HGCPKCDE_03138 1.3e-49 yviE
HGCPKCDE_03139 7.8e-155 flgL N Belongs to the bacterial flagellin family
HGCPKCDE_03140 2e-264 flgK N flagellar hook-associated protein
HGCPKCDE_03141 4.1e-78 flgN NOU FlgN protein
HGCPKCDE_03142 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
HGCPKCDE_03143 4.6e-73 yvyF S flagellar protein
HGCPKCDE_03144 2e-124 comFC S Phosphoribosyl transferase domain
HGCPKCDE_03145 3.7e-45 comFB S Late competence development protein ComFB
HGCPKCDE_03146 5.8e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HGCPKCDE_03147 7.3e-155 degV S protein conserved in bacteria
HGCPKCDE_03148 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGCPKCDE_03149 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HGCPKCDE_03150 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HGCPKCDE_03151 5.9e-163 yvhJ K Transcriptional regulator
HGCPKCDE_03152 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HGCPKCDE_03153 8.6e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HGCPKCDE_03154 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HGCPKCDE_03155 1.1e-113 tuaF M protein involved in exopolysaccharide biosynthesis
HGCPKCDE_03156 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
HGCPKCDE_03157 2e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGCPKCDE_03158 3.4e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HGCPKCDE_03159 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGCPKCDE_03160 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HGCPKCDE_03161 1.9e-94 M Glycosyltransferase like family 2
HGCPKCDE_03162 2.2e-207 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HGCPKCDE_03163 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HGCPKCDE_03164 7.7e-12
HGCPKCDE_03165 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HGCPKCDE_03166 3.5e-216 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HGCPKCDE_03167 2.1e-88 M Glycosyltransferase like family 2
HGCPKCDE_03168 1.6e-99 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HGCPKCDE_03169 1.1e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HGCPKCDE_03170 4.5e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HGCPKCDE_03171 3.5e-267 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HGCPKCDE_03172 1e-132 tagG GM Transport permease protein
HGCPKCDE_03173 2.2e-88
HGCPKCDE_03174 2.1e-55
HGCPKCDE_03175 9.6e-209 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HGCPKCDE_03176 6.5e-89 ggaA M Glycosyltransferase like family 2
HGCPKCDE_03177 1.5e-145 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HGCPKCDE_03178 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HGCPKCDE_03179 9.2e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HGCPKCDE_03180 4.6e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HGCPKCDE_03181 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HGCPKCDE_03182 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HGCPKCDE_03183 2e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HGCPKCDE_03184 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HGCPKCDE_03185 2.8e-216 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGCPKCDE_03186 2.1e-190 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HGCPKCDE_03187 3.5e-266 gerBA EG Spore germination protein
HGCPKCDE_03188 5.4e-198 gerBB E Spore germination protein
HGCPKCDE_03189 4.6e-213 gerAC S Spore germination protein
HGCPKCDE_03190 1.2e-247 ywtG EGP Major facilitator Superfamily
HGCPKCDE_03191 8.4e-171 ywtF K Transcriptional regulator
HGCPKCDE_03192 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HGCPKCDE_03193 2.9e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HGCPKCDE_03194 1.4e-20 ywtC
HGCPKCDE_03195 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HGCPKCDE_03196 8.6e-70 pgsC S biosynthesis protein
HGCPKCDE_03197 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HGCPKCDE_03198 2.7e-177 rbsR K transcriptional
HGCPKCDE_03199 6.5e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGCPKCDE_03200 9e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HGCPKCDE_03201 9.5e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HGCPKCDE_03202 9.3e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HGCPKCDE_03203 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HGCPKCDE_03204 1.2e-91 batE T Sh3 type 3 domain protein
HGCPKCDE_03205 8e-48 ywsA S Protein of unknown function (DUF3892)
HGCPKCDE_03206 4.4e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HGCPKCDE_03207 6.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HGCPKCDE_03208 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HGCPKCDE_03209 1.1e-169 alsR K LysR substrate binding domain
HGCPKCDE_03210 7.2e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HGCPKCDE_03211 3.1e-124 ywrJ
HGCPKCDE_03212 3.5e-210 cotH M Spore Coat
HGCPKCDE_03213 3.7e-12
HGCPKCDE_03214 2.4e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGCPKCDE_03215 5e-54 S Domain of unknown function (DUF4181)
HGCPKCDE_03216 7.2e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HGCPKCDE_03217 8e-82 ywrC K Transcriptional regulator
HGCPKCDE_03218 1.2e-103 ywrB P Chromate transporter
HGCPKCDE_03219 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
HGCPKCDE_03221 3.3e-100 ywqN S NAD(P)H-dependent
HGCPKCDE_03222 4.9e-162 K Transcriptional regulator
HGCPKCDE_03223 6.7e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HGCPKCDE_03224 3.9e-25
HGCPKCDE_03225 3.5e-242 ywqJ S Pre-toxin TG
HGCPKCDE_03226 3.9e-38 ywqI S Family of unknown function (DUF5344)
HGCPKCDE_03227 9.7e-23 S Domain of unknown function (DUF5082)
HGCPKCDE_03228 6e-151 ywqG S Domain of unknown function (DUF1963)
HGCPKCDE_03229 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGCPKCDE_03230 2.5e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HGCPKCDE_03231 3.2e-116 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HGCPKCDE_03232 2e-116 ywqC M biosynthesis protein
HGCPKCDE_03233 1.2e-17
HGCPKCDE_03234 2.3e-306 ywqB S SWIM zinc finger
HGCPKCDE_03235 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HGCPKCDE_03236 2.3e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HGCPKCDE_03237 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HGCPKCDE_03238 9.8e-58 ssbB L Single-stranded DNA-binding protein
HGCPKCDE_03239 1.9e-65 ywpG
HGCPKCDE_03240 1.1e-66 ywpF S YwpF-like protein
HGCPKCDE_03241 2.5e-83 srtA 3.4.22.70 M Sortase family
HGCPKCDE_03242 8.2e-274 M1-568 M cell wall anchor domain
HGCPKCDE_03243 0.0 M1-568 M cell wall anchor domain
HGCPKCDE_03244 9e-174 M1-574 T Transcriptional regulatory protein, C terminal
HGCPKCDE_03245 0.0 ywpD T PhoQ Sensor
HGCPKCDE_03246 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HGCPKCDE_03247 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HGCPKCDE_03248 7.5e-197 S aspartate phosphatase
HGCPKCDE_03249 2.6e-141 flhP N flagellar basal body
HGCPKCDE_03250 8.4e-124 flhO N flagellar basal body
HGCPKCDE_03251 3.5e-180 mbl D Rod shape-determining protein
HGCPKCDE_03252 3e-44 spoIIID K Stage III sporulation protein D
HGCPKCDE_03253 2.1e-70 ywoH K COG1846 Transcriptional regulators
HGCPKCDE_03254 6e-211 ywoG EGP Major facilitator Superfamily
HGCPKCDE_03255 1.2e-229 ywoF P Right handed beta helix region
HGCPKCDE_03256 1.4e-278 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HGCPKCDE_03257 1.2e-239 ywoD EGP Major facilitator superfamily
HGCPKCDE_03258 1.2e-103 phzA Q Isochorismatase family
HGCPKCDE_03259 2.2e-76
HGCPKCDE_03260 4.3e-225 amt P Ammonium transporter
HGCPKCDE_03261 1.6e-58 nrgB K Belongs to the P(II) protein family
HGCPKCDE_03262 1e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HGCPKCDE_03263 9e-69 ywnJ S VanZ like family
HGCPKCDE_03264 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HGCPKCDE_03265 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HGCPKCDE_03266 7.5e-09 ywnC S Family of unknown function (DUF5362)
HGCPKCDE_03267 3.7e-70 ywnF S Family of unknown function (DUF5392)
HGCPKCDE_03268 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGCPKCDE_03269 1.6e-143 mta K transcriptional
HGCPKCDE_03270 1.7e-58 ywnC S Family of unknown function (DUF5362)
HGCPKCDE_03271 6.4e-111 ywnB S NAD(P)H-binding
HGCPKCDE_03272 1.7e-64 ywnA K Transcriptional regulator
HGCPKCDE_03273 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HGCPKCDE_03274 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HGCPKCDE_03275 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HGCPKCDE_03276 3.8e-11 csbD K CsbD-like
HGCPKCDE_03277 3e-84 ywmF S Peptidase M50
HGCPKCDE_03278 1.3e-103 S response regulator aspartate phosphatase
HGCPKCDE_03279 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HGCPKCDE_03280 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HGCPKCDE_03282 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HGCPKCDE_03283 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HGCPKCDE_03284 6e-175 spoIID D Stage II sporulation protein D
HGCPKCDE_03285 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGCPKCDE_03286 3.7e-134 ywmB S TATA-box binding
HGCPKCDE_03287 1.3e-32 ywzB S membrane
HGCPKCDE_03288 9e-86 ywmA
HGCPKCDE_03289 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HGCPKCDE_03290 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HGCPKCDE_03291 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HGCPKCDE_03292 1.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HGCPKCDE_03293 3.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGCPKCDE_03294 3.9e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HGCPKCDE_03295 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGCPKCDE_03296 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HGCPKCDE_03297 2.5e-62 atpI S ATP synthase
HGCPKCDE_03298 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HGCPKCDE_03299 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HGCPKCDE_03300 7.2e-95 ywlG S Belongs to the UPF0340 family
HGCPKCDE_03301 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HGCPKCDE_03302 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGCPKCDE_03303 1.7e-91 mntP P Probably functions as a manganese efflux pump
HGCPKCDE_03304 5.2e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HGCPKCDE_03305 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HGCPKCDE_03306 6.1e-112 spoIIR S stage II sporulation protein R
HGCPKCDE_03307 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
HGCPKCDE_03309 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HGCPKCDE_03310 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HGCPKCDE_03311 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCPKCDE_03312 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HGCPKCDE_03313 8.6e-160 ywkB S Membrane transport protein
HGCPKCDE_03314 0.0 sfcA 1.1.1.38 C malic enzyme
HGCPKCDE_03315 7e-104 tdk 2.7.1.21 F thymidine kinase
HGCPKCDE_03316 1.1e-32 rpmE J Binds the 23S rRNA
HGCPKCDE_03317 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HGCPKCDE_03318 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HGCPKCDE_03319 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGCPKCDE_03320 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HGCPKCDE_03321 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HGCPKCDE_03322 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HGCPKCDE_03323 1.2e-91 ywjG S Domain of unknown function (DUF2529)
HGCPKCDE_03324 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HGCPKCDE_03325 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HGCPKCDE_03326 3.1e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HGCPKCDE_03327 0.0 fadF C COG0247 Fe-S oxidoreductase
HGCPKCDE_03328 1.3e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HGCPKCDE_03329 4.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HGCPKCDE_03330 7.9e-42 ywjC
HGCPKCDE_03331 7.6e-94 ywjB H RibD C-terminal domain
HGCPKCDE_03332 0.0 ywjA V ABC transporter
HGCPKCDE_03333 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGCPKCDE_03334 2e-123 narI 1.7.5.1 C nitrate reductase, gamma
HGCPKCDE_03335 1.4e-93 narJ 1.7.5.1 C nitrate reductase
HGCPKCDE_03336 2.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
HGCPKCDE_03337 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGCPKCDE_03338 7e-86 arfM T cyclic nucleotide binding
HGCPKCDE_03339 5.3e-138 ywiC S YwiC-like protein
HGCPKCDE_03340 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
HGCPKCDE_03341 2.3e-213 narK P COG2223 Nitrate nitrite transporter
HGCPKCDE_03342 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HGCPKCDE_03343 4.7e-73 ywiB S protein conserved in bacteria
HGCPKCDE_03344 1e-07 S Bacteriocin subtilosin A
HGCPKCDE_03345 1.3e-270 C Fe-S oxidoreductases
HGCPKCDE_03347 3.3e-132 cbiO V ABC transporter
HGCPKCDE_03348 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HGCPKCDE_03349 2.3e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
HGCPKCDE_03350 1e-248 L Peptidase, M16
HGCPKCDE_03352 8.6e-246 ywhL CO amine dehydrogenase activity
HGCPKCDE_03353 1.1e-197 ywhK CO amine dehydrogenase activity
HGCPKCDE_03354 2.6e-78 S aspartate phosphatase
HGCPKCDE_03357 1.7e-20
HGCPKCDE_03360 1.4e-57 V ATPases associated with a variety of cellular activities
HGCPKCDE_03362 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HGCPKCDE_03363 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HGCPKCDE_03364 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HGCPKCDE_03365 2e-94 ywhD S YwhD family
HGCPKCDE_03366 5.1e-119 ywhC S Peptidase family M50
HGCPKCDE_03367 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HGCPKCDE_03368 9.5e-71 ywhA K Transcriptional regulator
HGCPKCDE_03369 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGCPKCDE_03371 1.5e-237 mmr U Major Facilitator Superfamily
HGCPKCDE_03372 6.2e-79 yffB K Transcriptional regulator
HGCPKCDE_03373 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HGCPKCDE_03374 5.1e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HGCPKCDE_03375 3.1e-36 ywzC S Belongs to the UPF0741 family
HGCPKCDE_03376 6e-111 rsfA_1
HGCPKCDE_03377 7.5e-158 ywfM EG EamA-like transporter family
HGCPKCDE_03378 1.1e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HGCPKCDE_03379 5.2e-159 cysL K Transcriptional regulator
HGCPKCDE_03380 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HGCPKCDE_03381 3.3e-146 ywfI C May function as heme-dependent peroxidase
HGCPKCDE_03382 1.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
HGCPKCDE_03383 3.3e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
HGCPKCDE_03384 8.6e-210 bacE EGP Major facilitator Superfamily
HGCPKCDE_03385 6.1e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HGCPKCDE_03386 1.9e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGCPKCDE_03387 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HGCPKCDE_03388 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HGCPKCDE_03389 6e-206 ywfA EGP Major facilitator Superfamily
HGCPKCDE_03390 7.4e-250 lysP E amino acid
HGCPKCDE_03391 0.0 rocB E arginine degradation protein
HGCPKCDE_03392 2.5e-294 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HGCPKCDE_03393 2.8e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HGCPKCDE_03394 1.2e-77
HGCPKCDE_03395 1.3e-86 spsL 5.1.3.13 M Spore Coat
HGCPKCDE_03396 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGCPKCDE_03397 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGCPKCDE_03398 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HGCPKCDE_03399 8.8e-187 spsG M Spore Coat
HGCPKCDE_03400 2.4e-130 spsF M Spore Coat
HGCPKCDE_03401 6e-213 spsE 2.5.1.56 M acid synthase
HGCPKCDE_03402 1.2e-163 spsD 2.3.1.210 K Spore Coat
HGCPKCDE_03403 3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
HGCPKCDE_03404 2.3e-267 spsB M Capsule polysaccharide biosynthesis protein
HGCPKCDE_03405 1.8e-144 spsA M Spore Coat
HGCPKCDE_03406 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HGCPKCDE_03407 4.3e-59 ywdK S small membrane protein
HGCPKCDE_03408 2.4e-237 ywdJ F Xanthine uracil
HGCPKCDE_03409 6.6e-48 ywdI S Family of unknown function (DUF5327)
HGCPKCDE_03410 1.9e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HGCPKCDE_03411 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HGCPKCDE_03412 1.2e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
HGCPKCDE_03414 1.4e-113 ywdD
HGCPKCDE_03415 1.3e-57 pex K Transcriptional regulator PadR-like family
HGCPKCDE_03416 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HGCPKCDE_03417 7e-29 ywdA
HGCPKCDE_03418 9.5e-288 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HGCPKCDE_03419 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCPKCDE_03420 5.7e-138 focA P Formate/nitrite transporter
HGCPKCDE_03421 9.1e-150 sacT K transcriptional antiterminator
HGCPKCDE_03423 0.0 vpr O Belongs to the peptidase S8 family
HGCPKCDE_03424 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCPKCDE_03425 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HGCPKCDE_03426 8.6e-202 rodA D Belongs to the SEDS family
HGCPKCDE_03427 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HGCPKCDE_03428 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HGCPKCDE_03429 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HGCPKCDE_03430 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HGCPKCDE_03431 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HGCPKCDE_03432 1e-35 ywzA S membrane
HGCPKCDE_03433 7.5e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HGCPKCDE_03434 1.4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HGCPKCDE_03435 1.4e-58 gtcA S GtrA-like protein
HGCPKCDE_03436 1.1e-121 ywcC K transcriptional regulator
HGCPKCDE_03438 2.4e-47 ywcB S Protein of unknown function, DUF485
HGCPKCDE_03439 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGCPKCDE_03440 1.1e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HGCPKCDE_03441 4.9e-224 ywbN P Dyp-type peroxidase family protein
HGCPKCDE_03442 3.2e-185 ycdO P periplasmic lipoprotein involved in iron transport
HGCPKCDE_03443 1.9e-251 P COG0672 High-affinity Fe2 Pb2 permease
HGCPKCDE_03444 2.2e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HGCPKCDE_03445 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HGCPKCDE_03446 4.3e-153 ywbI K Transcriptional regulator
HGCPKCDE_03447 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HGCPKCDE_03448 5.2e-111 ywbG M effector of murein hydrolase
HGCPKCDE_03449 1.1e-207 ywbF EGP Major facilitator Superfamily
HGCPKCDE_03450 3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HGCPKCDE_03451 5.4e-220 ywbD 2.1.1.191 J Methyltransferase
HGCPKCDE_03452 9.9e-67 ywbC 4.4.1.5 E glyoxalase
HGCPKCDE_03453 1.3e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGCPKCDE_03454 3.7e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
HGCPKCDE_03455 2.4e-240 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCPKCDE_03456 1.9e-150 sacY K transcriptional antiterminator
HGCPKCDE_03457 2.9e-167 gspA M General stress
HGCPKCDE_03458 2.1e-123 ywaF S Integral membrane protein
HGCPKCDE_03459 2.3e-87 ywaE K Transcriptional regulator
HGCPKCDE_03460 1.2e-230 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGCPKCDE_03461 1.3e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HGCPKCDE_03462 1.1e-44 K Helix-turn-helix XRE-family like proteins
HGCPKCDE_03463 2.6e-36 K Helix-turn-helix domain
HGCPKCDE_03464 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
HGCPKCDE_03465 3.4e-129 ynfM EGP Major facilitator Superfamily
HGCPKCDE_03466 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HGCPKCDE_03467 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HGCPKCDE_03468 5e-14 S D-Ala-teichoic acid biosynthesis protein
HGCPKCDE_03469 1.8e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCPKCDE_03470 1.2e-232 dltB M membrane protein involved in D-alanine export
HGCPKCDE_03471 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCPKCDE_03472 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HGCPKCDE_03473 2.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCPKCDE_03474 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HGCPKCDE_03475 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HGCPKCDE_03476 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HGCPKCDE_03477 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGCPKCDE_03478 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HGCPKCDE_03479 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HGCPKCDE_03480 1.1e-19 yxzF
HGCPKCDE_03481 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HGCPKCDE_03482 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HGCPKCDE_03483 9e-215 yxlH EGP Major facilitator Superfamily
HGCPKCDE_03484 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HGCPKCDE_03485 7e-164 yxlF V ABC transporter, ATP-binding protein
HGCPKCDE_03486 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HGCPKCDE_03487 1.4e-30
HGCPKCDE_03488 3.9e-48 yxlC S Family of unknown function (DUF5345)
HGCPKCDE_03489 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HGCPKCDE_03490 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HGCPKCDE_03491 1.7e-156 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HGCPKCDE_03492 0.0 cydD V ATP-binding protein
HGCPKCDE_03493 0.0 cydD V ATP-binding
HGCPKCDE_03494 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HGCPKCDE_03495 2.2e-268 cydA 1.10.3.14 C oxidase, subunit
HGCPKCDE_03496 1.5e-229 cimH C COG3493 Na citrate symporter
HGCPKCDE_03497 4.4e-308 3.4.24.84 O Peptidase family M48
HGCPKCDE_03499 5.6e-155 yxkH G Polysaccharide deacetylase
HGCPKCDE_03500 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HGCPKCDE_03501 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
HGCPKCDE_03502 4.8e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGCPKCDE_03503 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HGCPKCDE_03504 1.4e-73 yxkC S Domain of unknown function (DUF4352)
HGCPKCDE_03505 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HGCPKCDE_03506 6.7e-95 yxkA S Phosphatidylethanolamine-binding protein
HGCPKCDE_03507 3.8e-162 yxjO K LysR substrate binding domain
HGCPKCDE_03508 3.4e-77 S Protein of unknown function (DUF1453)
HGCPKCDE_03509 3.5e-190 yxjM T Signal transduction histidine kinase
HGCPKCDE_03510 7.1e-113 K helix_turn_helix, Lux Regulon
HGCPKCDE_03511 6.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HGCPKCDE_03514 7.9e-85 yxjI S LURP-one-related
HGCPKCDE_03515 5.7e-219 yxjG 2.1.1.14 E Methionine synthase
HGCPKCDE_03516 2.2e-218 yxjG 2.1.1.14 E Methionine synthase
HGCPKCDE_03517 2.4e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HGCPKCDE_03518 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HGCPKCDE_03519 2.6e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HGCPKCDE_03520 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HGCPKCDE_03521 1.2e-143 rlmA 2.1.1.187 Q Methyltransferase domain
HGCPKCDE_03522 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGCPKCDE_03523 9.5e-81 T Domain of unknown function (DUF4163)
HGCPKCDE_03524 8.7e-47 yxiS
HGCPKCDE_03525 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HGCPKCDE_03526 6.6e-224 citH C Citrate transporter
HGCPKCDE_03527 1.1e-143 exoK GH16 M licheninase activity
HGCPKCDE_03528 8.3e-151 licT K transcriptional antiterminator
HGCPKCDE_03529 1.4e-111
HGCPKCDE_03530 1.6e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
HGCPKCDE_03531 5.3e-262 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HGCPKCDE_03532 1.1e-214 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HGCPKCDE_03533 5.5e-53 padR K Transcriptional regulator PadR-like family
HGCPKCDE_03534 2.2e-61 S Protein of unknown function (DUF2812)
HGCPKCDE_03537 9.5e-41 yxiJ S YxiJ-like protein
HGCPKCDE_03538 1.5e-83 yxiI S Protein of unknown function (DUF2716)
HGCPKCDE_03539 6.5e-135
HGCPKCDE_03540 6.9e-66 yxiG
HGCPKCDE_03541 8e-17
HGCPKCDE_03542 4.9e-160 yxxF EG EamA-like transporter family
HGCPKCDE_03543 4.1e-72 yxiE T Belongs to the universal stress protein A family
HGCPKCDE_03544 1.6e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGCPKCDE_03545 1.5e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HGCPKCDE_03547 1.4e-77 S SMI1 / KNR4 family
HGCPKCDE_03548 2.4e-311 S nuclease activity
HGCPKCDE_03549 2.3e-38 yxiC S Family of unknown function (DUF5344)
HGCPKCDE_03550 1e-20 S Domain of unknown function (DUF5082)
HGCPKCDE_03551 2.7e-279 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HGCPKCDE_03552 1.1e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HGCPKCDE_03553 5.7e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
HGCPKCDE_03554 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HGCPKCDE_03555 6.7e-237 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HGCPKCDE_03556 3.7e-179 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HGCPKCDE_03557 3.4e-250 lysP E amino acid
HGCPKCDE_03558 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HGCPKCDE_03559 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGCPKCDE_03560 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HGCPKCDE_03561 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HGCPKCDE_03562 1.3e-151 yxxB S Domain of Unknown Function (DUF1206)
HGCPKCDE_03563 9e-193 eutH E Ethanolamine utilisation protein, EutH
HGCPKCDE_03564 1.1e-248 yxeQ S MmgE/PrpD family
HGCPKCDE_03565 2e-211 yxeP 3.5.1.47 E hydrolase activity
HGCPKCDE_03566 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HGCPKCDE_03567 1.2e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
HGCPKCDE_03568 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HGCPKCDE_03569 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGCPKCDE_03570 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGCPKCDE_03571 3e-184 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HGCPKCDE_03572 2.2e-148 yidA S hydrolases of the HAD superfamily
HGCPKCDE_03575 1.3e-20 yxeE
HGCPKCDE_03576 5.6e-16 yxeD
HGCPKCDE_03577 1.4e-68
HGCPKCDE_03578 1.2e-174 fhuD P ABC transporter
HGCPKCDE_03579 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HGCPKCDE_03580 0.0 yxdM V ABC transporter (permease)
HGCPKCDE_03581 9.4e-141 yxdL V ABC transporter, ATP-binding protein
HGCPKCDE_03582 4.5e-180 T PhoQ Sensor
HGCPKCDE_03583 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCPKCDE_03584 6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HGCPKCDE_03585 1.1e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HGCPKCDE_03586 2.3e-167 iolH G Xylose isomerase-like TIM barrel
HGCPKCDE_03587 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HGCPKCDE_03588 1.1e-232 iolF EGP Major facilitator Superfamily
HGCPKCDE_03589 2.3e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HGCPKCDE_03590 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HGCPKCDE_03591 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HGCPKCDE_03592 3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HGCPKCDE_03593 1.8e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGCPKCDE_03594 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HGCPKCDE_03595 8.3e-176 iolS C Aldo keto reductase
HGCPKCDE_03597 8.3e-48 yxcD S Protein of unknown function (DUF2653)
HGCPKCDE_03598 1.9e-245 csbC EGP Major facilitator Superfamily
HGCPKCDE_03599 0.0 htpG O Molecular chaperone. Has ATPase activity
HGCPKCDE_03601 2e-149 IQ Enoyl-(Acyl carrier protein) reductase
HGCPKCDE_03602 5.4e-209 yxbF K Bacterial regulatory proteins, tetR family
HGCPKCDE_03603 1.3e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HGCPKCDE_03604 5.3e-30 yxaI S membrane protein domain
HGCPKCDE_03605 2.2e-91 S PQQ-like domain
HGCPKCDE_03606 1.1e-63 S Family of unknown function (DUF5391)
HGCPKCDE_03607 6.9e-75 yxaI S membrane protein domain
HGCPKCDE_03608 1.5e-225 P Protein of unknown function (DUF418)
HGCPKCDE_03609 3.5e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
HGCPKCDE_03610 2.1e-100 yxaF K Transcriptional regulator
HGCPKCDE_03611 7.3e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HGCPKCDE_03612 1.3e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
HGCPKCDE_03613 5.2e-50 S LrgA family
HGCPKCDE_03614 1.3e-117 yxaC M effector of murein hydrolase
HGCPKCDE_03615 3.1e-192 yxaB GM Polysaccharide pyruvyl transferase
HGCPKCDE_03616 7.8e-200 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HGCPKCDE_03617 7.3e-127 gntR K transcriptional
HGCPKCDE_03618 4.3e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HGCPKCDE_03619 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
HGCPKCDE_03620 3.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGCPKCDE_03621 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HGCPKCDE_03622 6.1e-285 ahpF O Alkyl hydroperoxide reductase
HGCPKCDE_03623 5.6e-189 wgaE S Polysaccharide pyruvyl transferase
HGCPKCDE_03624 3e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HGCPKCDE_03625 1e-16 bglF G phosphotransferase system
HGCPKCDE_03626 5.6e-124 yydK K Transcriptional regulator
HGCPKCDE_03627 2.2e-12
HGCPKCDE_03628 4.7e-118 S ABC-2 family transporter protein
HGCPKCDE_03629 1.6e-109 prrC P ABC transporter
HGCPKCDE_03630 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HGCPKCDE_03631 3.4e-73 cca 2.7.7.19, 2.7.7.72 J COG0617 tRNA nucleotidyltransferase poly(A) polymerase
HGCPKCDE_03632 7.6e-210 S Protein of unknown function DUF262
HGCPKCDE_03633 0.0 2.1.1.72, 3.1.21.4 L DEAD-like helicases superfamily
HGCPKCDE_03634 1e-99 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HGCPKCDE_03635 1.4e-121 spoIVCA L Recombinase zinc beta ribbon domain
HGCPKCDE_03636 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HGCPKCDE_03637 1.1e-09 S YyzF-like protein
HGCPKCDE_03638 7e-66
HGCPKCDE_03639 1.5e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HGCPKCDE_03641 2.6e-31 yycQ S Protein of unknown function (DUF2651)
HGCPKCDE_03642 1.2e-208 yycP
HGCPKCDE_03643 1.1e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HGCPKCDE_03644 3.2e-83 yycN 2.3.1.128 K Acetyltransferase
HGCPKCDE_03645 8.5e-188 S aspartate phosphatase
HGCPKCDE_03647 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HGCPKCDE_03648 1.4e-254 rocE E amino acid
HGCPKCDE_03649 5.8e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HGCPKCDE_03650 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HGCPKCDE_03651 1.5e-171 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HGCPKCDE_03652 3.4e-94 K PFAM response regulator receiver
HGCPKCDE_03653 3e-74 S Peptidase propeptide and YPEB domain
HGCPKCDE_03654 1.9e-33 S Peptidase propeptide and YPEB domain
HGCPKCDE_03655 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGCPKCDE_03656 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HGCPKCDE_03657 1.8e-153 yycI S protein conserved in bacteria
HGCPKCDE_03658 2e-258 yycH S protein conserved in bacteria
HGCPKCDE_03659 0.0 vicK 2.7.13.3 T Histidine kinase
HGCPKCDE_03660 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGCPKCDE_03665 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HGCPKCDE_03666 4.4e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCPKCDE_03667 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HGCPKCDE_03668 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HGCPKCDE_03670 1.9e-15 yycC K YycC-like protein
HGCPKCDE_03671 4.2e-220 yeaN P COG2807 Cyanate permease
HGCPKCDE_03672 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGCPKCDE_03673 2.2e-73 rplI J binds to the 23S rRNA
HGCPKCDE_03674 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HGCPKCDE_03675 2.9e-160 yybS S membrane
HGCPKCDE_03677 1.9e-83 cotF M Spore coat protein
HGCPKCDE_03678 6.8e-68 ydeP3 K Transcriptional regulator
HGCPKCDE_03679 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HGCPKCDE_03680 1.5e-58
HGCPKCDE_03682 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HGCPKCDE_03683 2.2e-110 K TipAS antibiotic-recognition domain
HGCPKCDE_03684 5.3e-123
HGCPKCDE_03685 1e-66 yybH S SnoaL-like domain
HGCPKCDE_03686 5.3e-121 yybG S Pentapeptide repeat-containing protein
HGCPKCDE_03687 2.2e-216 ynfM EGP Major facilitator Superfamily
HGCPKCDE_03688 2.6e-163 yybE K Transcriptional regulator
HGCPKCDE_03689 2e-79 yjcF S Acetyltransferase (GNAT) domain
HGCPKCDE_03690 2.3e-76 yybC
HGCPKCDE_03691 3e-127 S Metallo-beta-lactamase superfamily
HGCPKCDE_03692 5.6e-77 yybA 2.3.1.57 K transcriptional
HGCPKCDE_03693 6.5e-70 yjcF S Acetyltransferase (GNAT) domain
HGCPKCDE_03694 5.5e-96 yyaS S Membrane
HGCPKCDE_03695 4.2e-92 yyaR K Acetyltransferase (GNAT) domain
HGCPKCDE_03696 3.5e-66 yyaQ S YjbR
HGCPKCDE_03697 1.9e-106 yyaP 1.5.1.3 H RibD C-terminal domain
HGCPKCDE_03698 3.6e-244 tetL EGP Major facilitator Superfamily
HGCPKCDE_03699 8e-30 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HGCPKCDE_03700 1.9e-67
HGCPKCDE_03701 8.4e-64 ynaF
HGCPKCDE_03704 3.9e-22 yyaR K acetyltransferase
HGCPKCDE_03705 6.2e-76 yosT L Bacterial transcription activator, effector binding domain
HGCPKCDE_03706 1e-26 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HGCPKCDE_03707 2.1e-82 E Transglutaminase-like superfamily
HGCPKCDE_03708 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HGCPKCDE_03709 8e-168 yyaK S CAAX protease self-immunity
HGCPKCDE_03710 1e-243 EGP Major facilitator superfamily
HGCPKCDE_03711 4.7e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HGCPKCDE_03712 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGCPKCDE_03713 8.1e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HGCPKCDE_03714 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
HGCPKCDE_03715 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HGCPKCDE_03716 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HGCPKCDE_03717 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HGCPKCDE_03718 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HGCPKCDE_03719 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGCPKCDE_03720 2.3e-33 yyzM S protein conserved in bacteria
HGCPKCDE_03721 8.1e-177 yyaD S Membrane
HGCPKCDE_03722 2.8e-111 yyaC S Sporulation protein YyaC
HGCPKCDE_03723 2.1e-149 spo0J K Belongs to the ParB family
HGCPKCDE_03724 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HGCPKCDE_03725 9.6e-74 S Bacterial PH domain
HGCPKCDE_03726 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HGCPKCDE_03727 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HGCPKCDE_03728 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HGCPKCDE_03729 2.2e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HGCPKCDE_03730 6.5e-108 jag S single-stranded nucleic acid binding R3H
HGCPKCDE_03731 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGCPKCDE_03732 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HGCPKCDE_03733 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HGCPKCDE_03734 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HGCPKCDE_03735 2.4e-33 yaaA S S4 domain
HGCPKCDE_03736 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGCPKCDE_03737 1.8e-37 yaaB S Domain of unknown function (DUF370)
HGCPKCDE_03738 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGCPKCDE_03739 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGCPKCDE_03743 2e-08
HGCPKCDE_03744 9.3e-59
HGCPKCDE_03745 5.7e-25
HGCPKCDE_03746 6.2e-96 A Pre-toxin TG
HGCPKCDE_03747 9.5e-40 A Pre-toxin TG
HGCPKCDE_03748 1.2e-40
HGCPKCDE_03749 1e-15
HGCPKCDE_03750 4.4e-18 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HGCPKCDE_03753 6.9e-17
HGCPKCDE_03754 4.7e-124 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HGCPKCDE_03755 1.1e-55 K DNA binding
HGCPKCDE_03759 1.6e-22
HGCPKCDE_03761 3.8e-36 L Phage integrase, N-terminal SAM-like domain
HGCPKCDE_03764 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCPKCDE_03765 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGCPKCDE_03766 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HGCPKCDE_03767 1.1e-63 yngL S Protein of unknown function (DUF1360)
HGCPKCDE_03768 1e-303 yngK T Glycosyl hydrolase-like 10
HGCPKCDE_03769 5.4e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HGCPKCDE_03770 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HGCPKCDE_03771 1.2e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HGCPKCDE_03772 1.9e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HGCPKCDE_03773 5.8e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HGCPKCDE_03774 4.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HGCPKCDE_03775 1.7e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HGCPKCDE_03776 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
HGCPKCDE_03777 2.7e-103 yngC S membrane-associated protein
HGCPKCDE_03778 3.8e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HGCPKCDE_03779 2e-79 yngA S membrane
HGCPKCDE_03780 1.6e-296 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HGCPKCDE_03781 6.9e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HGCPKCDE_03783 3.4e-296 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HGCPKCDE_03784 9e-251 agcS E Sodium alanine symporter
HGCPKCDE_03785 1.3e-57 ynfC
HGCPKCDE_03786 2.3e-12
HGCPKCDE_03787 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGCPKCDE_03788 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGCPKCDE_03789 6.6e-69 yccU S CoA-binding protein
HGCPKCDE_03790 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HGCPKCDE_03791 4.1e-49 yneR S Belongs to the HesB IscA family
HGCPKCDE_03792 1.3e-53 yneQ
HGCPKCDE_03793 1.2e-73 yneP S Thioesterase-like superfamily
HGCPKCDE_03794 3.9e-35 tlp S Belongs to the Tlp family
HGCPKCDE_03795 3.1e-08 sspN S Small acid-soluble spore protein N family
HGCPKCDE_03797 1.2e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HGCPKCDE_03798 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HGCPKCDE_03799 2.2e-14 sspO S Belongs to the SspO family
HGCPKCDE_03800 3.9e-19 sspP S Belongs to the SspP family
HGCPKCDE_03801 2.2e-63 hspX O Spore coat protein
HGCPKCDE_03802 4e-64 yneK S Protein of unknown function (DUF2621)
HGCPKCDE_03803 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HGCPKCDE_03804 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HGCPKCDE_03805 7.1e-127 ccdA O cytochrome c biogenesis protein
HGCPKCDE_03806 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HGCPKCDE_03807 1.8e-28 yneF S UPF0154 protein
HGCPKCDE_03808 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HGCPKCDE_03809 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGCPKCDE_03810 1.3e-32 ynzC S UPF0291 protein
HGCPKCDE_03811 4.5e-112 yneB L resolvase
HGCPKCDE_03812 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HGCPKCDE_03813 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HGCPKCDE_03814 3.5e-76 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HGCPKCDE_03815 5.8e-74 yndM S Protein of unknown function (DUF2512)
HGCPKCDE_03816 3.1e-136 yndL S Replication protein
HGCPKCDE_03818 2.2e-304 yndJ S YndJ-like protein
HGCPKCDE_03819 8.7e-113 yndH S Domain of unknown function (DUF4166)
HGCPKCDE_03820 8.6e-153 yndG S DoxX-like family
HGCPKCDE_03821 4.2e-220 gerLC S Spore germination protein
HGCPKCDE_03822 4.5e-197 gerAB U Spore germination
HGCPKCDE_03823 5.7e-286 gerAA EG Spore germination protein
HGCPKCDE_03827 1.5e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HGCPKCDE_03828 1.8e-71
HGCPKCDE_03829 7.9e-25 tatA U protein secretion
HGCPKCDE_03832 5.5e-130 S Domain of unknown function, YrpD
HGCPKCDE_03834 8.6e-164 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGCPKCDE_03837 4e-15
HGCPKCDE_03838 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HGCPKCDE_03839 6.5e-81 yncE S Protein of unknown function (DUF2691)
HGCPKCDE_03840 8.5e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGCPKCDE_03841 2.3e-254 iolT EGP Major facilitator Superfamily
HGCPKCDE_03842 6.4e-111 yokF 3.1.31.1 L RNA catabolic process
HGCPKCDE_03843 9.6e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HGCPKCDE_03844 9.2e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HGCPKCDE_03845 1.1e-212 xylR GK ROK family
HGCPKCDE_03846 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HGCPKCDE_03847 2.3e-254 xynT G MFS/sugar transport protein
HGCPKCDE_03848 6.2e-75 yhbS S family acetyltransferase
HGCPKCDE_03849 5.3e-78 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HGCPKCDE_03852 5.8e-112 ynaE S Domain of unknown function (DUF3885)
HGCPKCDE_03853 1.5e-22 K Cro/C1-type HTH DNA-binding domain
HGCPKCDE_03854 4.7e-08 S Uncharacterised protein family (UPF0715)
HGCPKCDE_03855 3.6e-75 S CAAX protease self-immunity
HGCPKCDE_03857 8.9e-98 ynaD J Acetyltransferase (GNAT) domain
HGCPKCDE_03859 4.9e-217 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
HGCPKCDE_03860 1.3e-196 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HGCPKCDE_03861 2.2e-120 H Methionine biosynthesis protein MetW
HGCPKCDE_03862 2.2e-93 M Glycosyltransferase like family
HGCPKCDE_03863 2.4e-69 Q Collagen triple helix repeat (20 copies)
HGCPKCDE_03864 1e-31
HGCPKCDE_03865 5e-10
HGCPKCDE_03868 4.7e-35 S Terminase
HGCPKCDE_03869 1.8e-79 L phage terminase small subunit
HGCPKCDE_03870 4.4e-48 V HNH endonuclease
HGCPKCDE_03875 3.1e-18 N HicA toxin of bacterial toxin-antitoxin,
HGCPKCDE_03876 5.4e-66 S regulation of transcription, DNA-dependent
HGCPKCDE_03877 2.7e-26 S FRG
HGCPKCDE_03878 1.5e-50 wecC 1.1.1.336 M ArpU family transcriptional regulator
HGCPKCDE_03881 1.6e-21
HGCPKCDE_03882 2.9e-102 dnaB 3.6.4.12 L replicative DNA helicase
HGCPKCDE_03883 2.3e-38 L Arm DNA-binding domain
HGCPKCDE_03884 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
HGCPKCDE_03885 3.3e-68 glnR K transcriptional
HGCPKCDE_03886 3.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HGCPKCDE_03887 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HGCPKCDE_03888 1.7e-176 spoVK O stage V sporulation protein K
HGCPKCDE_03889 2.3e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HGCPKCDE_03890 2e-109 ymaB
HGCPKCDE_03891 1e-187 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGCPKCDE_03892 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGCPKCDE_03893 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HGCPKCDE_03894 4.5e-22 ymzA
HGCPKCDE_03895 8.2e-23
HGCPKCDE_03896 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HGCPKCDE_03897 6e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HGCPKCDE_03898 2.1e-46 ymaF S YmaF family
HGCPKCDE_03900 4.9e-51 ebrA P Small Multidrug Resistance protein
HGCPKCDE_03901 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HGCPKCDE_03902 1e-78 ymaD O redox protein, regulator of disulfide bond formation
HGCPKCDE_03903 1.3e-125 ymaC S Replication protein
HGCPKCDE_03904 1.9e-07 K Transcriptional regulator
HGCPKCDE_03905 1.9e-250 aprX O Belongs to the peptidase S8 family
HGCPKCDE_03906 1.4e-161 ymaE S Metallo-beta-lactamase superfamily
HGCPKCDE_03907 1.2e-61 ymzB
HGCPKCDE_03908 2.4e-231 cypA C Cytochrome P450
HGCPKCDE_03909 0.0 pks13 HQ Beta-ketoacyl synthase
HGCPKCDE_03910 0.0 dhbF IQ polyketide synthase
HGCPKCDE_03911 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HGCPKCDE_03912 0.0 pfaA Q Polyketide synthase of type I
HGCPKCDE_03913 0.0 rhiB IQ polyketide synthase
HGCPKCDE_03914 2.6e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HGCPKCDE_03915 2.5e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
HGCPKCDE_03916 3.9e-245 pksG 2.3.3.10 I synthase
HGCPKCDE_03917 2.5e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HGCPKCDE_03918 1.4e-37 acpK IQ Phosphopantetheine attachment site
HGCPKCDE_03919 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HGCPKCDE_03920 1.3e-184 pksD Q Acyl transferase domain
HGCPKCDE_03922 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HGCPKCDE_03923 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HGCPKCDE_03924 1.3e-108 pksA K Transcriptional regulator
HGCPKCDE_03925 1.8e-96 ymcC S Membrane
HGCPKCDE_03927 4.1e-67 S Regulatory protein YrvL
HGCPKCDE_03928 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HGCPKCDE_03929 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HGCPKCDE_03930 2.2e-88 cotE S Spore coat protein
HGCPKCDE_03931 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HGCPKCDE_03932 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HGCPKCDE_03933 8e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HGCPKCDE_03934 3.9e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HGCPKCDE_03935 1.2e-36 spoVS S Stage V sporulation protein S
HGCPKCDE_03936 1.9e-152 ymdB S protein conserved in bacteria
HGCPKCDE_03937 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HGCPKCDE_03938 1.3e-213 pbpX V Beta-lactamase
HGCPKCDE_03939 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HGCPKCDE_03940 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
HGCPKCDE_03941 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGCPKCDE_03942 1.9e-124 ymfM S protein conserved in bacteria
HGCPKCDE_03943 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HGCPKCDE_03944 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HGCPKCDE_03945 4.6e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HGCPKCDE_03946 5.1e-240 ymfH S zinc protease
HGCPKCDE_03947 6e-233 ymfF S Peptidase M16
HGCPKCDE_03948 3.8e-205 ymfD EGP Major facilitator Superfamily
HGCPKCDE_03949 1.4e-133 ymfC K Transcriptional regulator
HGCPKCDE_03950 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HGCPKCDE_03951 6.4e-31 S YlzJ-like protein
HGCPKCDE_03952 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HGCPKCDE_03953 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGCPKCDE_03954 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGCPKCDE_03955 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HGCPKCDE_03956 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGCPKCDE_03957 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HGCPKCDE_03958 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HGCPKCDE_03959 2.6e-42 ymxH S YlmC YmxH family
HGCPKCDE_03960 4.4e-233 pepR S Belongs to the peptidase M16 family
HGCPKCDE_03961 9.4e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HGCPKCDE_03962 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HGCPKCDE_03963 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HGCPKCDE_03964 2.3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HGCPKCDE_03965 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HGCPKCDE_03966 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HGCPKCDE_03967 3e-44 ylxP S protein conserved in bacteria
HGCPKCDE_03968 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGCPKCDE_03969 3.1e-47 ylxQ J ribosomal protein
HGCPKCDE_03970 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HGCPKCDE_03971 1.1e-203 nusA K Participates in both transcription termination and antitermination
HGCPKCDE_03972 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HGCPKCDE_03973 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGCPKCDE_03974 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HGCPKCDE_03975 7.7e-233 rasP M zinc metalloprotease
HGCPKCDE_03976 8.6e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HGCPKCDE_03977 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HGCPKCDE_03978 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HGCPKCDE_03979 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HGCPKCDE_03980 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HGCPKCDE_03981 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HGCPKCDE_03982 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HGCPKCDE_03983 3.1e-76 ylxL
HGCPKCDE_03984 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCPKCDE_03985 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HGCPKCDE_03986 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HGCPKCDE_03987 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HGCPKCDE_03988 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HGCPKCDE_03989 4.9e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HGCPKCDE_03990 2.2e-157 flhG D Belongs to the ParA family
HGCPKCDE_03991 1.5e-200 flhF N Flagellar biosynthesis regulator FlhF
HGCPKCDE_03992 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HGCPKCDE_03993 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HGCPKCDE_03994 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HGCPKCDE_03995 2.2e-36 fliQ N Role in flagellar biosynthesis
HGCPKCDE_03996 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HGCPKCDE_03997 2.7e-96 fliZ N Flagellar biosynthesis protein, FliO
HGCPKCDE_03998 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HGCPKCDE_03999 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HGCPKCDE_04000 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HGCPKCDE_04001 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HGCPKCDE_04002 8.2e-140 flgG N Flagellar basal body rod
HGCPKCDE_04003 1.7e-72 flgD N Flagellar basal body rod modification protein
HGCPKCDE_04004 4.6e-221 fliK N Flagellar hook-length control protein
HGCPKCDE_04005 1.1e-35 ylxF S MgtE intracellular N domain
HGCPKCDE_04006 3.2e-69 fliJ N Flagellar biosynthesis chaperone
HGCPKCDE_04007 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HGCPKCDE_04008 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HGCPKCDE_04009 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HGCPKCDE_04010 2.4e-255 fliF N The M ring may be actively involved in energy transduction
HGCPKCDE_04011 1.9e-31 fliE N Flagellar hook-basal body
HGCPKCDE_04012 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
HGCPKCDE_04013 6.8e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HGCPKCDE_04014 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HGCPKCDE_04015 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HGCPKCDE_04016 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HGCPKCDE_04017 2.5e-169 xerC L tyrosine recombinase XerC
HGCPKCDE_04018 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HGCPKCDE_04019 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGCPKCDE_04020 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HGCPKCDE_04021 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HGCPKCDE_04022 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HGCPKCDE_04023 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HGCPKCDE_04024 1e-288 ylqG
HGCPKCDE_04025 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGCPKCDE_04026 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HGCPKCDE_04027 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HGCPKCDE_04028 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HGCPKCDE_04029 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HGCPKCDE_04030 1.4e-60 ylqD S YlqD protein
HGCPKCDE_04031 1.7e-35 ylqC S Belongs to the UPF0109 family
HGCPKCDE_04032 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HGCPKCDE_04033 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGCPKCDE_04034 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HGCPKCDE_04035 2.9e-87
HGCPKCDE_04036 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HGCPKCDE_04037 0.0 smc D Required for chromosome condensation and partitioning
HGCPKCDE_04038 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HGCPKCDE_04039 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGCPKCDE_04040 6.1e-129 IQ reductase
HGCPKCDE_04041 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HGCPKCDE_04042 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HGCPKCDE_04043 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HGCPKCDE_04044 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HGCPKCDE_04045 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HGCPKCDE_04046 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HGCPKCDE_04047 4.3e-300 yloV S kinase related to dihydroxyacetone kinase
HGCPKCDE_04048 1.2e-58 asp S protein conserved in bacteria
HGCPKCDE_04049 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HGCPKCDE_04050 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HGCPKCDE_04051 8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HGCPKCDE_04052 1.9e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HGCPKCDE_04053 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HGCPKCDE_04054 1.6e-140 stp 3.1.3.16 T phosphatase
HGCPKCDE_04055 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HGCPKCDE_04056 7.1e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HGCPKCDE_04057 2e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGCPKCDE_04058 3.3e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGCPKCDE_04059 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGCPKCDE_04060 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HGCPKCDE_04061 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HGCPKCDE_04062 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HGCPKCDE_04063 1.5e-40 ylzA S Belongs to the UPF0296 family
HGCPKCDE_04064 2.4e-156 yloC S stress-induced protein
HGCPKCDE_04065 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HGCPKCDE_04066 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HGCPKCDE_04067 1.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HGCPKCDE_04068 4.9e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HGCPKCDE_04069 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HGCPKCDE_04070 6.2e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HGCPKCDE_04071 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HGCPKCDE_04072 5.4e-179 cysP P phosphate transporter
HGCPKCDE_04073 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HGCPKCDE_04075 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGCPKCDE_04076 1.1e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HGCPKCDE_04077 3.9e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HGCPKCDE_04078 2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HGCPKCDE_04079 0.0 carB 6.3.5.5 F Belongs to the CarB family
HGCPKCDE_04080 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HGCPKCDE_04081 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HGCPKCDE_04082 5.9e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HGCPKCDE_04083 2.9e-230 pyrP F Xanthine uracil
HGCPKCDE_04084 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HGCPKCDE_04085 1.9e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGCPKCDE_04086 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HGCPKCDE_04087 1.3e-63 dksA T COG1734 DnaK suppressor protein
HGCPKCDE_04088 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HGCPKCDE_04089 2.6e-67 divIVA D Cell division initiation protein
HGCPKCDE_04090 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HGCPKCDE_04091 1.3e-39 yggT S membrane
HGCPKCDE_04092 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HGCPKCDE_04093 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HGCPKCDE_04094 6.6e-156 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HGCPKCDE_04095 2.4e-37 ylmC S sporulation protein
HGCPKCDE_04096 2.6e-252 argE 3.5.1.16 E Acetylornithine deacetylase
HGCPKCDE_04097 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HGCPKCDE_04098 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCPKCDE_04099 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGCPKCDE_04100 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HGCPKCDE_04101 0.0 bpr O COG1404 Subtilisin-like serine proteases
HGCPKCDE_04102 3.6e-42 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGCPKCDE_04103 1.7e-305 Q Non-ribosomal peptide synthetase modules and related proteins

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)