ORF_ID e_value Gene_name EC_number CAZy COGs Description
JFDLEHCO_00001 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JFDLEHCO_00002 7.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JFDLEHCO_00003 2.4e-33 yaaA S S4 domain
JFDLEHCO_00004 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JFDLEHCO_00005 8.1e-38 yaaB S Domain of unknown function (DUF370)
JFDLEHCO_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JFDLEHCO_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JFDLEHCO_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
JFDLEHCO_00011 1.8e-184 yaaC S YaaC-like Protein
JFDLEHCO_00012 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
JFDLEHCO_00013 1.2e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JFDLEHCO_00014 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JFDLEHCO_00015 2.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JFDLEHCO_00016 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JFDLEHCO_00017 5e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JFDLEHCO_00018 1.3e-09
JFDLEHCO_00019 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
JFDLEHCO_00020 1.1e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
JFDLEHCO_00021 8.9e-213 yaaH M Glycoside Hydrolase Family
JFDLEHCO_00022 2e-100 yaaI Q COG1335 Amidases related to nicotinamidase
JFDLEHCO_00023 3.5e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JFDLEHCO_00024 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JFDLEHCO_00025 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JFDLEHCO_00026 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JFDLEHCO_00027 3.6e-32 yaaL S Protein of unknown function (DUF2508)
JFDLEHCO_00028 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
JFDLEHCO_00029 3.4e-39 S COG NOG14552 non supervised orthologous group
JFDLEHCO_00032 2.2e-30 csfB S Inhibitor of sigma-G Gin
JFDLEHCO_00033 1e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
JFDLEHCO_00034 1.1e-193 yaaN P Belongs to the TelA family
JFDLEHCO_00035 3.2e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
JFDLEHCO_00036 1.5e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JFDLEHCO_00037 7.5e-55 yaaQ S protein conserved in bacteria
JFDLEHCO_00038 5.3e-72 yaaR S protein conserved in bacteria
JFDLEHCO_00039 1.3e-182 holB 2.7.7.7 L DNA polymerase III
JFDLEHCO_00040 8.8e-145 yaaT S stage 0 sporulation protein
JFDLEHCO_00041 7.7e-37 yabA L Involved in initiation control of chromosome replication
JFDLEHCO_00042 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
JFDLEHCO_00043 4.7e-48 yazA L endonuclease containing a URI domain
JFDLEHCO_00044 1.4e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JFDLEHCO_00045 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
JFDLEHCO_00046 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JFDLEHCO_00047 1.6e-145 tatD L hydrolase, TatD
JFDLEHCO_00048 1.8e-232 rpfB GH23 T protein conserved in bacteria
JFDLEHCO_00049 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JFDLEHCO_00050 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JFDLEHCO_00051 8.4e-146 yabG S peptidase
JFDLEHCO_00052 7.8e-39 veg S protein conserved in bacteria
JFDLEHCO_00053 2.9e-27 sspF S DNA topological change
JFDLEHCO_00054 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JFDLEHCO_00055 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
JFDLEHCO_00056 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
JFDLEHCO_00057 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
JFDLEHCO_00058 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JFDLEHCO_00059 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JFDLEHCO_00060 2e-106 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JFDLEHCO_00061 2.5e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JFDLEHCO_00062 3.7e-40 yabK S Peptide ABC transporter permease
JFDLEHCO_00063 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JFDLEHCO_00064 6.2e-91 spoVT K stage V sporulation protein
JFDLEHCO_00065 2.6e-286 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JFDLEHCO_00066 8.3e-279 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
JFDLEHCO_00067 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
JFDLEHCO_00068 1.9e-49 yabP S Sporulation protein YabP
JFDLEHCO_00069 4.4e-104 yabQ S spore cortex biosynthesis protein
JFDLEHCO_00070 4.1e-57 divIC D Septum formation initiator
JFDLEHCO_00071 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
JFDLEHCO_00074 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
JFDLEHCO_00075 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
JFDLEHCO_00076 7.3e-186 KLT serine threonine protein kinase
JFDLEHCO_00077 2e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JFDLEHCO_00078 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JFDLEHCO_00079 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JFDLEHCO_00080 4.9e-139 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JFDLEHCO_00081 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JFDLEHCO_00082 3e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
JFDLEHCO_00083 1.5e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JFDLEHCO_00084 4.2e-272 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JFDLEHCO_00085 1e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
JFDLEHCO_00086 3.1e-164 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
JFDLEHCO_00087 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JFDLEHCO_00088 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JFDLEHCO_00089 9.9e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JFDLEHCO_00090 4.5e-29 yazB K transcriptional
JFDLEHCO_00091 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JFDLEHCO_00092 6.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JFDLEHCO_00093 3.4e-39 S COG NOG14552 non supervised orthologous group
JFDLEHCO_00095 1.3e-07
JFDLEHCO_00098 2e-08
JFDLEHCO_00103 3.4e-39 S COG NOG14552 non supervised orthologous group
JFDLEHCO_00104 7.5e-77 ctsR K Belongs to the CtsR family
JFDLEHCO_00105 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
JFDLEHCO_00106 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
JFDLEHCO_00107 0.0 clpC O Belongs to the ClpA ClpB family
JFDLEHCO_00108 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JFDLEHCO_00109 2.9e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JFDLEHCO_00110 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
JFDLEHCO_00111 1e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
JFDLEHCO_00112 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
JFDLEHCO_00113 2.8e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JFDLEHCO_00114 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
JFDLEHCO_00115 2.8e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JFDLEHCO_00116 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JFDLEHCO_00117 2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JFDLEHCO_00118 4.2e-89 yacP S RNA-binding protein containing a PIN domain
JFDLEHCO_00119 8.9e-116 sigH K Belongs to the sigma-70 factor family
JFDLEHCO_00120 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
JFDLEHCO_00121 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
JFDLEHCO_00122 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JFDLEHCO_00123 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JFDLEHCO_00124 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JFDLEHCO_00125 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JFDLEHCO_00126 9.7e-109 rsmC 2.1.1.172 J Methyltransferase
JFDLEHCO_00127 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JFDLEHCO_00128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JFDLEHCO_00129 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
JFDLEHCO_00130 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JFDLEHCO_00131 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JFDLEHCO_00132 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JFDLEHCO_00133 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JFDLEHCO_00134 4.7e-190 ybaC 3.4.11.5 S Alpha/beta hydrolase family
JFDLEHCO_00135 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
JFDLEHCO_00136 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JFDLEHCO_00137 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
JFDLEHCO_00138 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JFDLEHCO_00139 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JFDLEHCO_00140 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JFDLEHCO_00141 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JFDLEHCO_00142 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JFDLEHCO_00143 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JFDLEHCO_00144 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
JFDLEHCO_00145 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JFDLEHCO_00146 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JFDLEHCO_00147 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JFDLEHCO_00148 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JFDLEHCO_00149 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JFDLEHCO_00150 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JFDLEHCO_00151 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JFDLEHCO_00152 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JFDLEHCO_00153 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JFDLEHCO_00154 1.9e-23 rpmD J Ribosomal protein L30
JFDLEHCO_00155 1.1e-72 rplO J binds to the 23S rRNA
JFDLEHCO_00156 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JFDLEHCO_00157 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JFDLEHCO_00158 5.7e-143 map 3.4.11.18 E Methionine aminopeptidase
JFDLEHCO_00159 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JFDLEHCO_00160 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JFDLEHCO_00161 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JFDLEHCO_00162 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JFDLEHCO_00163 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JFDLEHCO_00164 4.7e-58 rplQ J Ribosomal protein L17
JFDLEHCO_00165 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JFDLEHCO_00166 1.3e-151 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JFDLEHCO_00167 5.3e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JFDLEHCO_00168 5.1e-144 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JFDLEHCO_00169 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JFDLEHCO_00170 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
JFDLEHCO_00171 9.6e-146 ybaJ Q Methyltransferase domain
JFDLEHCO_00172 1.8e-86 yizA S Damage-inducible protein DinB
JFDLEHCO_00173 4.5e-79 ybaK S Protein of unknown function (DUF2521)
JFDLEHCO_00174 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JFDLEHCO_00175 5.1e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
JFDLEHCO_00176 5.9e-76 gerD
JFDLEHCO_00177 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
JFDLEHCO_00178 8.4e-134 pdaB 3.5.1.104 G Polysaccharide deacetylase
JFDLEHCO_00179 3.4e-39 S COG NOG14552 non supervised orthologous group
JFDLEHCO_00182 1.6e-08
JFDLEHCO_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
JFDLEHCO_00186 2.2e-221 glcP G Major Facilitator Superfamily
JFDLEHCO_00187 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JFDLEHCO_00188 3.9e-181 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
JFDLEHCO_00189 5.3e-203 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
JFDLEHCO_00190 2.5e-227 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
JFDLEHCO_00191 9.7e-175 ybaS 1.1.1.58 S Na -dependent transporter
JFDLEHCO_00192 8.3e-118 ybbA S Putative esterase
JFDLEHCO_00193 1.2e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFDLEHCO_00194 2.8e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFDLEHCO_00195 2e-172 feuA P Iron-uptake system-binding protein
JFDLEHCO_00196 0.0 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
JFDLEHCO_00197 4.9e-240 ybbC 3.2.1.52 S protein conserved in bacteria
JFDLEHCO_00198 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
JFDLEHCO_00199 3.5e-249 yfeW 3.4.16.4 V Belongs to the UPF0214 family
JFDLEHCO_00200 1.8e-240 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JFDLEHCO_00201 9.5e-164 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JFDLEHCO_00202 3.7e-87 ybbJ J acetyltransferase
JFDLEHCO_00203 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
JFDLEHCO_00209 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
JFDLEHCO_00210 5.9e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
JFDLEHCO_00211 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JFDLEHCO_00212 1.6e-226 ybbR S protein conserved in bacteria
JFDLEHCO_00213 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JFDLEHCO_00214 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JFDLEHCO_00215 2.5e-158 V ATPases associated with a variety of cellular activities
JFDLEHCO_00216 2.1e-109 S ABC-2 family transporter protein
JFDLEHCO_00217 3.7e-28 ybdN
JFDLEHCO_00219 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JFDLEHCO_00220 4.7e-188 T PhoQ Sensor
JFDLEHCO_00221 4.3e-138 V ABC transporter, ATP-binding protein
JFDLEHCO_00222 0.0 V ABC transporter (permease)
JFDLEHCO_00223 3e-12 cusA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JFDLEHCO_00224 3.9e-164 dkgB S Aldo/keto reductase family
JFDLEHCO_00225 1e-93 yxaC M effector of murein hydrolase
JFDLEHCO_00226 6.9e-52 S LrgA family
JFDLEHCO_00227 8e-73 yxaD K helix_turn_helix multiple antibiotic resistance protein
JFDLEHCO_00228 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
JFDLEHCO_00229 2.7e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
JFDLEHCO_00230 5.1e-204 T COG4585 Signal transduction histidine kinase
JFDLEHCO_00231 2.9e-111 KT LuxR family transcriptional regulator
JFDLEHCO_00232 2.8e-171 V COG1131 ABC-type multidrug transport system, ATPase component
JFDLEHCO_00233 2.3e-210 V COG0842 ABC-type multidrug transport system, permease component
JFDLEHCO_00234 3e-204 V ABC-2 family transporter protein
JFDLEHCO_00235 5.8e-25
JFDLEHCO_00236 3.1e-78 S Domain of unknown function (DUF4879)
JFDLEHCO_00237 2e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
JFDLEHCO_00238 6.4e-112 yqeB
JFDLEHCO_00239 9.2e-40 ybyB
JFDLEHCO_00240 2.5e-292 ybeC E amino acid
JFDLEHCO_00242 1.9e-55
JFDLEHCO_00243 3.4e-15 S Protein of unknown function (DUF2651)
JFDLEHCO_00244 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JFDLEHCO_00245 1.7e-259 glpT G -transporter
JFDLEHCO_00246 1.3e-16 S Protein of unknown function (DUF2651)
JFDLEHCO_00247 5e-212 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
JFDLEHCO_00249 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
JFDLEHCO_00250 1.3e-30
JFDLEHCO_00251 1.2e-82 K Helix-turn-helix XRE-family like proteins
JFDLEHCO_00252 7e-203 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
JFDLEHCO_00253 6.2e-213 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JFDLEHCO_00254 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JFDLEHCO_00255 1.9e-86 ybfM S SNARE associated Golgi protein
JFDLEHCO_00256 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
JFDLEHCO_00257 6.5e-44 ybfN
JFDLEHCO_00258 2.7e-193 yceA S Belongs to the UPF0176 family
JFDLEHCO_00259 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JFDLEHCO_00260 8.6e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JFDLEHCO_00261 4.7e-258 mmuP E amino acid
JFDLEHCO_00262 1.1e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
JFDLEHCO_00263 5.4e-259 agcS E Sodium alanine symporter
JFDLEHCO_00264 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
JFDLEHCO_00265 1.4e-213 phoQ 2.7.13.3 T Histidine kinase
JFDLEHCO_00266 6.7e-173 glnL T Regulator
JFDLEHCO_00267 8.2e-26 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
JFDLEHCO_00268 1.8e-156 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JFDLEHCO_00269 1.5e-112 ydfN C nitroreductase
JFDLEHCO_00270 6.2e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
JFDLEHCO_00271 1.5e-62 mhqP S DoxX
JFDLEHCO_00272 2.8e-57 traF CO Thioredoxin
JFDLEHCO_00273 5.6e-62 ycbP S Protein of unknown function (DUF2512)
JFDLEHCO_00274 5.1e-80 sleB 3.5.1.28 M Cell wall
JFDLEHCO_00275 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
JFDLEHCO_00276 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
JFDLEHCO_00277 5.6e-127 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JFDLEHCO_00278 3.1e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JFDLEHCO_00279 6.7e-212 ycbU E Selenocysteine lyase
JFDLEHCO_00280 7.1e-243 lmrB EGP the major facilitator superfamily
JFDLEHCO_00281 5.3e-101 yxaF K Transcriptional regulator
JFDLEHCO_00282 4.7e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
JFDLEHCO_00283 8.7e-116 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
JFDLEHCO_00284 1.5e-197 yccF K DNA-templated transcriptional preinitiation complex assembly
JFDLEHCO_00285 4.6e-174 yccK C Aldo keto reductase
JFDLEHCO_00286 5.6e-178 ycdA S Domain of unknown function (DUF5105)
JFDLEHCO_00287 2.6e-274 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
JFDLEHCO_00288 7.9e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
JFDLEHCO_00289 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
JFDLEHCO_00290 4.2e-190 S response regulator aspartate phosphatase
JFDLEHCO_00291 5e-142 IQ Enoyl-(Acyl carrier protein) reductase
JFDLEHCO_00292 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
JFDLEHCO_00293 1.2e-164 adcA P Belongs to the bacterial solute-binding protein 9 family
JFDLEHCO_00294 1.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
JFDLEHCO_00295 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
JFDLEHCO_00296 3.3e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JFDLEHCO_00297 4.3e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
JFDLEHCO_00298 3.7e-105 yceD T proteins involved in stress response, homologs of TerZ and
JFDLEHCO_00299 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
JFDLEHCO_00300 9.7e-138 terC P Protein of unknown function (DUF475)
JFDLEHCO_00301 0.0 yceG S Putative component of 'biosynthetic module'
JFDLEHCO_00302 2.3e-193 yceH P Belongs to the TelA family
JFDLEHCO_00303 3.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
JFDLEHCO_00304 3.9e-229 proV 3.6.3.32 E glycine betaine
JFDLEHCO_00305 1.6e-138 opuAB P glycine betaine
JFDLEHCO_00306 3.1e-164 opuAC E glycine betaine
JFDLEHCO_00307 2.1e-213 amhX S amidohydrolase
JFDLEHCO_00308 1.1e-230 ycgA S Membrane
JFDLEHCO_00309 2.2e-82 ycgB
JFDLEHCO_00310 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
JFDLEHCO_00311 5.7e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JFDLEHCO_00312 9.6e-262 mdr EGP Major facilitator Superfamily
JFDLEHCO_00313 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
JFDLEHCO_00314 4.7e-114 ycgF E Lysine exporter protein LysE YggA
JFDLEHCO_00315 1.6e-153 yqcI S YqcI/YcgG family
JFDLEHCO_00316 9.8e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
JFDLEHCO_00317 7.6e-114 ycgI S Domain of unknown function (DUF1989)
JFDLEHCO_00318 4.8e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JFDLEHCO_00320 4.3e-109 tmrB S AAA domain
JFDLEHCO_00321 2.7e-151 4.2.1.118 G Xylose isomerase-like TIM barrel
JFDLEHCO_00322 1.2e-233 G COG0477 Permeases of the major facilitator superfamily
JFDLEHCO_00323 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JFDLEHCO_00324 4.5e-185 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
JFDLEHCO_00325 3.6e-148 ycgL S Predicted nucleotidyltransferase
JFDLEHCO_00326 2.3e-170 ycgM E Proline dehydrogenase
JFDLEHCO_00327 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
JFDLEHCO_00328 2.2e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JFDLEHCO_00329 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
JFDLEHCO_00330 5.3e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JFDLEHCO_00331 2.7e-282 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
JFDLEHCO_00332 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
JFDLEHCO_00333 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JFDLEHCO_00334 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JFDLEHCO_00335 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
JFDLEHCO_00336 2.1e-224 nasA P COG2223 Nitrate nitrite transporter
JFDLEHCO_00337 1.3e-229 yciC S GTPases (G3E family)
JFDLEHCO_00338 1.4e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
JFDLEHCO_00339 5.6e-74 yckC S membrane
JFDLEHCO_00340 2.2e-51 S Protein of unknown function (DUF2680)
JFDLEHCO_00341 3.8e-297 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JFDLEHCO_00342 2.9e-69 nin S Competence protein J (ComJ)
JFDLEHCO_00343 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
JFDLEHCO_00344 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
JFDLEHCO_00345 5.1e-108 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
JFDLEHCO_00346 2.8e-63 hxlR K transcriptional
JFDLEHCO_00347 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_00348 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_00349 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
JFDLEHCO_00350 1.5e-140 srfAD Q thioesterase
JFDLEHCO_00351 7.2e-250 bamJ E Aminotransferase class I and II
JFDLEHCO_00352 1.3e-64 S YcxB-like protein
JFDLEHCO_00354 3.2e-170 ycxC EG EamA-like transporter family
JFDLEHCO_00355 4.6e-249 ycxD K GntR family transcriptional regulator
JFDLEHCO_00356 1.6e-131 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
JFDLEHCO_00357 1.3e-111 yczE S membrane
JFDLEHCO_00358 1.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JFDLEHCO_00359 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
JFDLEHCO_00360 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
JFDLEHCO_00361 3.9e-159 bsdA K LysR substrate binding domain
JFDLEHCO_00362 6.4e-102 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
JFDLEHCO_00363 6.3e-284 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
JFDLEHCO_00364 2e-38 bsdD 4.1.1.61 S response to toxic substance
JFDLEHCO_00365 5.2e-78 yclD
JFDLEHCO_00366 3.2e-270 dtpT E amino acid peptide transporter
JFDLEHCO_00367 2.7e-284 yclG M Pectate lyase superfamily protein
JFDLEHCO_00369 4.9e-296 gerKA EG Spore germination protein
JFDLEHCO_00370 1.6e-238 gerKC S spore germination
JFDLEHCO_00371 3.9e-196 gerKB F Spore germination protein
JFDLEHCO_00372 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JFDLEHCO_00373 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JFDLEHCO_00374 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
JFDLEHCO_00375 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
JFDLEHCO_00376 4.1e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
JFDLEHCO_00377 1.8e-220 yxeP 3.5.1.47 E hydrolase activity
JFDLEHCO_00378 2.8e-257 yxeQ S MmgE/PrpD family
JFDLEHCO_00379 2.4e-124 yclH P ABC transporter
JFDLEHCO_00380 7.9e-242 yclI V ABC transporter (permease) YclI
JFDLEHCO_00381 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JFDLEHCO_00382 2.8e-263 T PhoQ Sensor
JFDLEHCO_00383 4e-79 S aspartate phosphatase
JFDLEHCO_00386 2.6e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
JFDLEHCO_00387 2.3e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFDLEHCO_00388 3.6e-166 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFDLEHCO_00389 8.1e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
JFDLEHCO_00390 1.9e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
JFDLEHCO_00391 2.7e-250 ycnB EGP Major facilitator Superfamily
JFDLEHCO_00392 1.1e-153 ycnC K Transcriptional regulator
JFDLEHCO_00393 1.4e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
JFDLEHCO_00394 3.6e-45 ycnE S Monooxygenase
JFDLEHCO_00395 8.8e-53 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
JFDLEHCO_00396 2.8e-268 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JFDLEHCO_00397 5.3e-221 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JFDLEHCO_00398 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JFDLEHCO_00399 3.6e-149 glcU U Glucose uptake
JFDLEHCO_00400 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JFDLEHCO_00401 3.5e-98 ycnI S protein conserved in bacteria
JFDLEHCO_00402 1e-301 ycnJ P protein, homolog of Cu resistance protein CopC
JFDLEHCO_00403 5e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
JFDLEHCO_00404 1.6e-55
JFDLEHCO_00405 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
JFDLEHCO_00406 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
JFDLEHCO_00407 6.6e-212 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
JFDLEHCO_00408 3.2e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
JFDLEHCO_00410 2.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JFDLEHCO_00411 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
JFDLEHCO_00412 4.7e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
JFDLEHCO_00413 1.1e-152 ycsI S Belongs to the D-glutamate cyclase family
JFDLEHCO_00414 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
JFDLEHCO_00415 9e-192 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
JFDLEHCO_00416 1.1e-131 kipR K Transcriptional regulator
JFDLEHCO_00417 8.4e-119 ycsK E anatomical structure formation involved in morphogenesis
JFDLEHCO_00419 5.1e-56 yczJ S biosynthesis
JFDLEHCO_00420 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
JFDLEHCO_00421 3.1e-175 ydhF S Oxidoreductase
JFDLEHCO_00422 0.0 mtlR K transcriptional regulator, MtlR
JFDLEHCO_00423 4.3e-291 ydaB IQ acyl-CoA ligase
JFDLEHCO_00424 9.7e-163 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JFDLEHCO_00425 9.3e-97 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
JFDLEHCO_00426 1.4e-118 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JFDLEHCO_00427 1.4e-77 ydaG 1.4.3.5 S general stress protein
JFDLEHCO_00428 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
JFDLEHCO_00429 2.7e-48 ydzA EGP Major facilitator Superfamily
JFDLEHCO_00430 1.5e-74 lrpC K Transcriptional regulator
JFDLEHCO_00431 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JFDLEHCO_00432 4e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
JFDLEHCO_00433 2.7e-149 ydaK T Diguanylate cyclase, GGDEF domain
JFDLEHCO_00434 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
JFDLEHCO_00435 8.5e-232 ydaM M Glycosyl transferase family group 2
JFDLEHCO_00436 0.0 ydaN S Bacterial cellulose synthase subunit
JFDLEHCO_00437 0.0 ydaO E amino acid
JFDLEHCO_00438 2.2e-78 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
JFDLEHCO_00439 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JFDLEHCO_00440 2.2e-75 K acetyltransferase
JFDLEHCO_00442 7.4e-46
JFDLEHCO_00443 3.7e-210 S Histidine kinase
JFDLEHCO_00445 3.6e-11
JFDLEHCO_00447 5.1e-80
JFDLEHCO_00448 3.5e-100
JFDLEHCO_00449 7.2e-40
JFDLEHCO_00450 2.4e-226 mntH P H( )-stimulated, divalent metal cation uptake system
JFDLEHCO_00452 6.5e-34 ydaT
JFDLEHCO_00453 5.8e-73 yvaD S Family of unknown function (DUF5360)
JFDLEHCO_00454 4.1e-54 yvaE P Small Multidrug Resistance protein
JFDLEHCO_00455 1.8e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
JFDLEHCO_00457 9.6e-64 ydbB G Cupin domain
JFDLEHCO_00458 6.3e-63 ydbC S Domain of unknown function (DUF4937
JFDLEHCO_00459 6.5e-156 ydbD P Catalase
JFDLEHCO_00460 2.2e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
JFDLEHCO_00461 5.9e-302 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JFDLEHCO_00462 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
JFDLEHCO_00463 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JFDLEHCO_00464 3.2e-160 ydbI S AI-2E family transporter
JFDLEHCO_00465 5e-173 ydbJ V ABC transporter, ATP-binding protein
JFDLEHCO_00466 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JFDLEHCO_00467 2.1e-52 ydbL
JFDLEHCO_00468 1.2e-208 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
JFDLEHCO_00469 1.5e-10 S Fur-regulated basic protein B
JFDLEHCO_00470 5.8e-09 S Fur-regulated basic protein A
JFDLEHCO_00471 1.1e-60 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JFDLEHCO_00472 5e-82 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JFDLEHCO_00473 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JFDLEHCO_00474 3.2e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JFDLEHCO_00475 4.7e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JFDLEHCO_00476 1.3e-250 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JFDLEHCO_00477 2.1e-82 ydbS S Bacterial PH domain
JFDLEHCO_00478 1.2e-266 ydbT S Membrane
JFDLEHCO_00479 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
JFDLEHCO_00480 5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JFDLEHCO_00481 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
JFDLEHCO_00482 1.3e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JFDLEHCO_00483 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
JFDLEHCO_00484 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
JFDLEHCO_00485 6.1e-146 rsbR T Positive regulator of sigma-B
JFDLEHCO_00486 1.8e-57 rsbS T antagonist
JFDLEHCO_00487 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
JFDLEHCO_00488 4.6e-188 rsbU 3.1.3.3 KT phosphatase
JFDLEHCO_00489 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
JFDLEHCO_00490 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
JFDLEHCO_00491 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JFDLEHCO_00492 2.3e-110 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
JFDLEHCO_00493 0.0 yhgF K COG2183 Transcriptional accessory protein
JFDLEHCO_00494 1.7e-14
JFDLEHCO_00495 1.3e-59 ydcK S Belongs to the SprT family
JFDLEHCO_00503 8.7e-98 ywrO 1.6.5.2 S Flavodoxin-like fold
JFDLEHCO_00504 3.1e-74 S SnoaL-like polyketide cyclase
JFDLEHCO_00505 4.4e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
JFDLEHCO_00506 2.4e-71 lrpA K transcriptional
JFDLEHCO_00507 2.6e-157 S Serine aminopeptidase, S33
JFDLEHCO_00508 7.4e-261 proP EGP Transporter
JFDLEHCO_00509 2.6e-49 ohrR K Transcriptional regulator
JFDLEHCO_00510 5.4e-86 S Domain of unknown function with cystatin-like fold (DUF4467)
JFDLEHCO_00511 1.4e-74 maoC I N-terminal half of MaoC dehydratase
JFDLEHCO_00512 3.8e-65 yyaQ S YjbR
JFDLEHCO_00513 5.1e-75 ywnA K Transcriptional regulator
JFDLEHCO_00514 5.3e-113 ywnB S NAD(P)H-binding
JFDLEHCO_00515 4.9e-102 K Bacterial regulatory proteins, tetR family
JFDLEHCO_00516 9.1e-133 C Enoyl-(Acyl carrier protein) reductase
JFDLEHCO_00517 6.8e-184 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
JFDLEHCO_00518 2.4e-178 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
JFDLEHCO_00519 6.9e-56 K Transcriptional regulator
JFDLEHCO_00520 1e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
JFDLEHCO_00521 1.4e-30 cspL K Cold shock
JFDLEHCO_00522 1.2e-79 carD K Transcription factor
JFDLEHCO_00523 9.2e-40 yrkD S protein conserved in bacteria
JFDLEHCO_00524 1.1e-83 yrkE O DsrE/DsrF/DrsH-like family
JFDLEHCO_00525 3.4e-64 P Rhodanese Homology Domain
JFDLEHCO_00526 1.8e-101 yrkF OP Belongs to the sulfur carrier protein TusA family
JFDLEHCO_00527 2.2e-199 yrkH P Rhodanese Homology Domain
JFDLEHCO_00528 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
JFDLEHCO_00529 3.5e-119 yrkJ S membrane transporter protein
JFDLEHCO_00530 2e-126 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
JFDLEHCO_00531 2.3e-107 S Protein of unknown function (DUF2812)
JFDLEHCO_00532 3.4e-52 K Transcriptional regulator PadR-like family
JFDLEHCO_00533 1.2e-174 ybfA 3.4.15.5 K FR47-like protein
JFDLEHCO_00534 1.8e-237 ybfB G COG0477 Permeases of the major facilitator superfamily
JFDLEHCO_00535 2.3e-184 S Patatin-like phospholipase
JFDLEHCO_00536 1.3e-84 S DinB superfamily
JFDLEHCO_00537 8.8e-65 G Cupin domain
JFDLEHCO_00540 1.6e-268 ygaK C COG0277 FAD FMN-containing dehydrogenases
JFDLEHCO_00541 1.5e-79 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JFDLEHCO_00542 1.8e-170 czcD P COG1230 Co Zn Cd efflux system component
JFDLEHCO_00543 4.4e-202 trkA P Oxidoreductase
JFDLEHCO_00545 7e-103 yrkC G Cupin domain
JFDLEHCO_00547 2.6e-88 ykkA S Protein of unknown function (DUF664)
JFDLEHCO_00548 1.6e-150 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
JFDLEHCO_00550 2.4e-200 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
JFDLEHCO_00551 9.3e-57 ydeH
JFDLEHCO_00552 7.5e-85 F nucleoside 2-deoxyribosyltransferase
JFDLEHCO_00553 1.3e-195 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JFDLEHCO_00554 1.2e-148 Q ubiE/COQ5 methyltransferase family
JFDLEHCO_00555 2.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JFDLEHCO_00556 1.4e-234 3.1.3.41 G Haloacid dehalogenase-like hydrolase
JFDLEHCO_00557 2.4e-170 S Sodium Bile acid symporter family
JFDLEHCO_00558 4e-203 adhA 1.1.1.1 C alcohol dehydrogenase
JFDLEHCO_00559 3.6e-67 yraB K helix_turn_helix, mercury resistance
JFDLEHCO_00560 3.1e-229 mleN_2 C antiporter
JFDLEHCO_00561 5.8e-266 K helix_turn_helix gluconate operon transcriptional repressor
JFDLEHCO_00562 8.4e-116 paiB K Transcriptional regulator
JFDLEHCO_00564 8.5e-113 ksgA1 I Ribosomal RNA adenine dimethylase
JFDLEHCO_00565 5.4e-124 T Transcriptional regulator
JFDLEHCO_00566 1.1e-192 T PhoQ Sensor
JFDLEHCO_00567 2.8e-106 S SNARE associated Golgi protein
JFDLEHCO_00568 2.7e-187 ydeR EGP Major facilitator Superfamily
JFDLEHCO_00569 4.5e-103 ydeS K Transcriptional regulator
JFDLEHCO_00570 3.3e-158 ydeK EG -transporter
JFDLEHCO_00571 3.9e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JFDLEHCO_00572 1.9e-49 yraD M Spore coat protein
JFDLEHCO_00573 7.5e-26 yraE
JFDLEHCO_00574 2.2e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
JFDLEHCO_00575 9.9e-64 yraF M Spore coat protein
JFDLEHCO_00576 6.9e-37 yraG
JFDLEHCO_00577 1.8e-221 ydfH 2.7.13.3 T Histidine kinase
JFDLEHCO_00578 3.7e-111 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JFDLEHCO_00579 0.0 ydfJ S drug exporters of the RND superfamily
JFDLEHCO_00580 9.1e-137 puuD S Peptidase C26
JFDLEHCO_00581 2.6e-302 expZ S ABC transporter
JFDLEHCO_00582 5.9e-102 ynaD J Acetyltransferase (GNAT) domain
JFDLEHCO_00583 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
JFDLEHCO_00584 1.6e-197 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
JFDLEHCO_00585 7.9e-211 tcaB EGP Major facilitator Superfamily
JFDLEHCO_00586 1.2e-227 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JFDLEHCO_00587 2.7e-157 K Helix-turn-helix XRE-family like proteins
JFDLEHCO_00588 1.3e-123 ydhB S membrane transporter protein
JFDLEHCO_00589 2.4e-83 bltD 2.3.1.57 K FR47-like protein
JFDLEHCO_00590 5.7e-152 bltR K helix_turn_helix, mercury resistance
JFDLEHCO_00591 2.3e-151 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JFDLEHCO_00592 1.1e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
JFDLEHCO_00593 2.3e-147 ycgJ_1 Q ubiE/COQ5 methyltransferase family
JFDLEHCO_00594 3e-156 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
JFDLEHCO_00595 3.1e-21 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
JFDLEHCO_00596 1.3e-120 ydhC K FCD
JFDLEHCO_00597 1.7e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
JFDLEHCO_00600 1.6e-268 pbpE V Beta-lactamase
JFDLEHCO_00602 2.5e-98 ydhK M Protein of unknown function (DUF1541)
JFDLEHCO_00603 1.2e-195 pbuE EGP Major facilitator Superfamily
JFDLEHCO_00604 1.3e-133 ydhQ K UTRA
JFDLEHCO_00605 1.4e-119 K FCD
JFDLEHCO_00606 7.4e-217 yeaN P COG2807 Cyanate permease
JFDLEHCO_00607 2.6e-49 sugE P Small Multidrug Resistance protein
JFDLEHCO_00608 2.3e-51 ykkC P Small Multidrug Resistance protein
JFDLEHCO_00609 5.3e-104 yvdT K Transcriptional regulator
JFDLEHCO_00610 9.3e-297 yveA E amino acid
JFDLEHCO_00611 3.2e-166 ydhU P Catalase
JFDLEHCO_00612 6.4e-84 yndB S Activator of Hsp90 ATPase homolog 1-like protein
JFDLEHCO_00613 4.7e-185 yhfP 1.1.1.1 C Quinone oxidoreductase
JFDLEHCO_00614 1.2e-253 iolT EGP Major facilitator Superfamily
JFDLEHCO_00617 3.4e-39 S COG NOG14552 non supervised orthologous group
JFDLEHCO_00618 7.8e-08
JFDLEHCO_00620 1.4e-186 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JFDLEHCO_00621 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
JFDLEHCO_00622 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
JFDLEHCO_00623 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JFDLEHCO_00624 2.7e-191 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JFDLEHCO_00625 0.0 ydiF S ABC transporter
JFDLEHCO_00626 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
JFDLEHCO_00627 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JFDLEHCO_00628 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
JFDLEHCO_00629 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JFDLEHCO_00630 1.7e-27 ydiK S Domain of unknown function (DUF4305)
JFDLEHCO_00631 2.5e-127 ydiL S CAAX protease self-immunity
JFDLEHCO_00632 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JFDLEHCO_00633 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JFDLEHCO_00634 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
JFDLEHCO_00637 4.2e-65
JFDLEHCO_00638 0.0 K NB-ARC domain
JFDLEHCO_00639 4.5e-202 gutB 1.1.1.14 E Dehydrogenase
JFDLEHCO_00640 2.3e-251 gutA G MFS/sugar transport protein
JFDLEHCO_00641 2.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
JFDLEHCO_00642 6.2e-30 yjdJ S Domain of unknown function (DUF4306)
JFDLEHCO_00643 2.7e-115 pspA KT Phage shock protein A
JFDLEHCO_00644 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JFDLEHCO_00645 3.3e-122 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
JFDLEHCO_00646 1.9e-157 ydjI S virion core protein (lumpy skin disease virus)
JFDLEHCO_00647 0.0 yrhL I Acyltransferase family
JFDLEHCO_00648 1.2e-147 rsiV S Protein of unknown function (DUF3298)
JFDLEHCO_00649 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
JFDLEHCO_00650 1.8e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
JFDLEHCO_00651 1.4e-62 ydjM M Lytic transglycolase
JFDLEHCO_00652 9.4e-136 ydjN U Involved in the tonB-independent uptake of proteins
JFDLEHCO_00654 7.2e-35 ydjO S Cold-inducible protein YdjO
JFDLEHCO_00655 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
JFDLEHCO_00656 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
JFDLEHCO_00657 5.8e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JFDLEHCO_00658 3.5e-177 yeaC S COG0714 MoxR-like ATPases
JFDLEHCO_00659 1.6e-216 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
JFDLEHCO_00660 0.0 yebA E COG1305 Transglutaminase-like enzymes
JFDLEHCO_00661 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JFDLEHCO_00662 7.8e-94 sigV K Belongs to the sigma-70 factor family. ECF subfamily
JFDLEHCO_00663 8.6e-273 S Domain of unknown function (DUF4179)
JFDLEHCO_00664 6.2e-209 pbuG S permease
JFDLEHCO_00665 3e-134 yebC M Membrane
JFDLEHCO_00667 3.1e-93 yebE S UPF0316 protein
JFDLEHCO_00668 5.5e-29 yebG S NETI protein
JFDLEHCO_00669 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JFDLEHCO_00670 7.2e-225 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JFDLEHCO_00671 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JFDLEHCO_00672 2.2e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JFDLEHCO_00673 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JFDLEHCO_00674 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JFDLEHCO_00675 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JFDLEHCO_00676 2.1e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JFDLEHCO_00677 4.2e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JFDLEHCO_00678 2.2e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JFDLEHCO_00679 4.1e-289 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JFDLEHCO_00680 6.1e-238 purD 6.3.4.13 F Belongs to the GARS family
JFDLEHCO_00681 1.2e-25 S Protein of unknown function (DUF2892)
JFDLEHCO_00682 0.0 yerA 3.5.4.2 F adenine deaminase
JFDLEHCO_00683 1.4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
JFDLEHCO_00684 2.4e-50 yerC S protein conserved in bacteria
JFDLEHCO_00685 7.9e-304 yerD 1.4.7.1 E Belongs to the glutamate synthase family
JFDLEHCO_00686 6.2e-128 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JFDLEHCO_00687 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JFDLEHCO_00688 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JFDLEHCO_00689 1.4e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
JFDLEHCO_00690 7.5e-199 yerI S homoserine kinase type II (protein kinase fold)
JFDLEHCO_00691 8.8e-122 sapB S MgtC SapB transporter
JFDLEHCO_00692 3.7e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JFDLEHCO_00693 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JFDLEHCO_00694 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JFDLEHCO_00695 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JFDLEHCO_00696 9.6e-155 yerO K Transcriptional regulator
JFDLEHCO_00697 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JFDLEHCO_00698 6.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JFDLEHCO_00699 9.9e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JFDLEHCO_00700 1.8e-300 hsdM 2.1.1.72 V Type I restriction-modification system
JFDLEHCO_00701 4e-234 3.1.21.3 V Type I restriction modification DNA specificity domain
JFDLEHCO_00702 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
JFDLEHCO_00704 3.5e-224 V Domain of unknown function (DUF3578)
JFDLEHCO_00705 2.6e-91 S Protein of unknown function, DUF600
JFDLEHCO_00706 4.5e-82 S Protein of unknown function, DUF600
JFDLEHCO_00707 2.9e-84 S Protein of unknown function, DUF600
JFDLEHCO_00708 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
JFDLEHCO_00709 9.4e-127 yeeN K transcriptional regulatory protein
JFDLEHCO_00711 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
JFDLEHCO_00712 3.3e-45 cotJB S CotJB protein
JFDLEHCO_00713 8.9e-104 cotJC P Spore Coat
JFDLEHCO_00714 1.6e-99 yesJ K Acetyltransferase (GNAT) family
JFDLEHCO_00716 8.7e-122 yetF S membrane
JFDLEHCO_00717 3.3e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
JFDLEHCO_00718 4e-65 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JFDLEHCO_00719 1.8e-156 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JFDLEHCO_00720 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
JFDLEHCO_00721 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
JFDLEHCO_00722 8.2e-106 yetJ S Belongs to the BI1 family
JFDLEHCO_00723 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
JFDLEHCO_00724 2.8e-210 yetM CH FAD binding domain
JFDLEHCO_00725 2.6e-197 yetN S Protein of unknown function (DUF3900)
JFDLEHCO_00726 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
JFDLEHCO_00728 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
JFDLEHCO_00729 6.7e-167 V ATPases associated with a variety of cellular activities
JFDLEHCO_00730 1.9e-127 V ABC-2 type transporter
JFDLEHCO_00731 6.4e-75 S protein homooligomerization
JFDLEHCO_00732 6.4e-128
JFDLEHCO_00733 1.6e-193 S ATP diphosphatase activity
JFDLEHCO_00734 1e-267 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
JFDLEHCO_00735 1e-153 sagB C Nitroreductase family
JFDLEHCO_00736 1e-114 S CAAX protease self-immunity
JFDLEHCO_00737 1.1e-147 2.1.1.163, 2.1.1.201 Q methyltransferase
JFDLEHCO_00739 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JFDLEHCO_00740 1.2e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
JFDLEHCO_00741 2.4e-172 yfnG 4.2.1.45 M dehydratase
JFDLEHCO_00742 1.4e-180 yfnF M Nucleotide-diphospho-sugar transferase
JFDLEHCO_00743 2.1e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
JFDLEHCO_00744 2.5e-188 yfnD M Nucleotide-diphospho-sugar transferase
JFDLEHCO_00745 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
JFDLEHCO_00746 4.2e-248 yfnA E amino acid
JFDLEHCO_00747 4.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JFDLEHCO_00748 9.8e-115 yfmS NT chemotaxis protein
JFDLEHCO_00749 5.2e-167 IQ Enoyl-(Acyl carrier protein) reductase
JFDLEHCO_00750 1.6e-210 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JFDLEHCO_00751 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JFDLEHCO_00752 6.2e-70 yfmP K transcriptional
JFDLEHCO_00753 2.1e-208 yfmO EGP Major facilitator Superfamily
JFDLEHCO_00754 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JFDLEHCO_00755 7.7e-208 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
JFDLEHCO_00756 3.6e-19 yfmK 2.3.1.128 K acetyltransferase
JFDLEHCO_00757 6.3e-33 yfmK 2.3.1.128 K acetyltransferase
JFDLEHCO_00758 2e-191 yfmJ S N-terminal domain of oxidoreductase
JFDLEHCO_00759 1.7e-24 S Protein of unknown function (DUF3212)
JFDLEHCO_00760 1.3e-57 yflT S Heat induced stress protein YflT
JFDLEHCO_00761 8.2e-243 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
JFDLEHCO_00762 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
JFDLEHCO_00763 2.8e-35 Q PFAM Collagen triple helix
JFDLEHCO_00764 7.4e-98 Q PFAM Collagen triple helix
JFDLEHCO_00765 8.9e-141 Q calcium- and calmodulin-responsive adenylate cyclase activity
JFDLEHCO_00766 4.8e-87 M1-820 Q Collagen triple helix repeat (20 copies)
JFDLEHCO_00767 6.5e-277 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JFDLEHCO_00768 9.5e-121 citT T response regulator
JFDLEHCO_00769 8.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
JFDLEHCO_00770 3.8e-227 citM C Citrate transporter
JFDLEHCO_00771 7.9e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
JFDLEHCO_00772 1.4e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JFDLEHCO_00773 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JFDLEHCO_00774 2.3e-124 yflK S protein conserved in bacteria
JFDLEHCO_00775 1.5e-14 yflJ S Protein of unknown function (DUF2639)
JFDLEHCO_00776 7e-19 yflI
JFDLEHCO_00777 3.1e-50 yflH S Protein of unknown function (DUF3243)
JFDLEHCO_00778 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
JFDLEHCO_00779 1.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
JFDLEHCO_00780 2.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
JFDLEHCO_00781 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JFDLEHCO_00782 7.8e-64 yhdN S Domain of unknown function (DUF1992)
JFDLEHCO_00783 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
JFDLEHCO_00784 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
JFDLEHCO_00785 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
JFDLEHCO_00786 6.6e-241 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JFDLEHCO_00787 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JFDLEHCO_00788 9e-130 treR K transcriptional
JFDLEHCO_00789 1.2e-123 yfkO C nitroreductase
JFDLEHCO_00790 4.2e-125 yibF S YibE/F-like protein
JFDLEHCO_00791 5.2e-204 yibE S YibE/F-like protein
JFDLEHCO_00793 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
JFDLEHCO_00794 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
JFDLEHCO_00795 3e-187 K helix_turn _helix lactose operon repressor
JFDLEHCO_00796 1.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JFDLEHCO_00797 7.3e-138 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JFDLEHCO_00798 1.3e-194 ydiM EGP Major facilitator Superfamily
JFDLEHCO_00799 7.1e-30 yfkK S Belongs to the UPF0435 family
JFDLEHCO_00800 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JFDLEHCO_00801 2e-52 yfkI S gas vesicle protein
JFDLEHCO_00802 6.8e-145 yihY S Belongs to the UPF0761 family
JFDLEHCO_00803 2.5e-07
JFDLEHCO_00804 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
JFDLEHCO_00805 1.3e-185 cax P COG0387 Ca2 H antiporter
JFDLEHCO_00806 1.9e-144 yfkD S YfkD-like protein
JFDLEHCO_00807 3.3e-147 yfkC M Mechanosensitive ion channel
JFDLEHCO_00808 2.7e-221 yfkA S YfkB-like domain
JFDLEHCO_00809 4.9e-27 yfjT
JFDLEHCO_00810 1.8e-155 pdaA G deacetylase
JFDLEHCO_00811 7.7e-152 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
JFDLEHCO_00812 5.4e-33
JFDLEHCO_00813 1.7e-184 corA P Mediates influx of magnesium ions
JFDLEHCO_00814 7.2e-166 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JFDLEHCO_00815 5.6e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JFDLEHCO_00816 2.7e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JFDLEHCO_00817 1.3e-95 yfjM S Psort location Cytoplasmic, score
JFDLEHCO_00818 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JFDLEHCO_00819 5e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JFDLEHCO_00820 8.6e-218 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JFDLEHCO_00821 1.5e-258 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JFDLEHCO_00822 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
JFDLEHCO_00823 4.2e-15 sspH S Belongs to the SspH family
JFDLEHCO_00824 1.2e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
JFDLEHCO_00825 1e-139 glvR F Helix-turn-helix domain, rpiR family
JFDLEHCO_00826 1e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JFDLEHCO_00827 0.0 yobO M COG5434 Endopolygalacturonase
JFDLEHCO_00828 0.0 yfiB3 V ABC transporter
JFDLEHCO_00829 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
JFDLEHCO_00830 2.4e-63 mhqP S DoxX
JFDLEHCO_00831 1.1e-161 yfiE 1.13.11.2 S glyoxalase
JFDLEHCO_00832 1.5e-172 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
JFDLEHCO_00833 1.7e-96 padR K transcriptional
JFDLEHCO_00834 6.5e-113 1.6.5.2 S NADPH-dependent FMN reductase
JFDLEHCO_00835 2.5e-184 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JFDLEHCO_00836 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
JFDLEHCO_00837 1.5e-45 yrdF K ribonuclease inhibitor
JFDLEHCO_00838 2.7e-102 yfiT S Belongs to the metal hydrolase YfiT family
JFDLEHCO_00839 6.4e-293 yfiU EGP Major facilitator Superfamily
JFDLEHCO_00840 5.6e-83 yfiV K transcriptional
JFDLEHCO_00841 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JFDLEHCO_00842 2.7e-168 yfhB 5.3.3.17 S PhzF family
JFDLEHCO_00843 3.3e-106 yfhC C nitroreductase
JFDLEHCO_00844 2.1e-25 yfhD S YfhD-like protein
JFDLEHCO_00846 3.3e-169 yfhF S nucleoside-diphosphate sugar epimerase
JFDLEHCO_00847 1.8e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
JFDLEHCO_00848 8.8e-53 yfhH S Protein of unknown function (DUF1811)
JFDLEHCO_00849 1.2e-206 yfhI EGP Major facilitator Superfamily
JFDLEHCO_00851 9.6e-169 mpr 3.4.21.19 M Belongs to the peptidase S1B family
JFDLEHCO_00852 4.4e-45 yfhJ S WVELL protein
JFDLEHCO_00853 1.8e-95 batE T Bacterial SH3 domain homologues
JFDLEHCO_00854 1.4e-35 yfhL S SdpI/YhfL protein family
JFDLEHCO_00855 1.5e-171 yfhM S Alpha/beta hydrolase family
JFDLEHCO_00856 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JFDLEHCO_00857 0.0 yfhO S Bacterial membrane protein YfhO
JFDLEHCO_00858 2.1e-185 yfhP S membrane-bound metal-dependent
JFDLEHCO_00859 2.7e-210 mutY L A G-specific
JFDLEHCO_00860 8.2e-37 yfhS
JFDLEHCO_00861 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JFDLEHCO_00863 1.5e-37 ygaB S YgaB-like protein
JFDLEHCO_00864 2.2e-104 ygaC J Belongs to the UPF0374 family
JFDLEHCO_00865 2.5e-306 ygaD V ABC transporter
JFDLEHCO_00866 1.1e-179 ygaE S Membrane
JFDLEHCO_00867 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
JFDLEHCO_00868 1.1e-86 bcp 1.11.1.15 O Peroxiredoxin
JFDLEHCO_00869 1.8e-80 perR P Belongs to the Fur family
JFDLEHCO_00870 1.5e-56 ygzB S UPF0295 protein
JFDLEHCO_00871 3.7e-165 ygxA S Nucleotidyltransferase-like
JFDLEHCO_00872 3.4e-39 S COG NOG14552 non supervised orthologous group
JFDLEHCO_00877 7.8e-08
JFDLEHCO_00885 1.6e-08
JFDLEHCO_00889 5.5e-289 C Na+/H+ antiporter family
JFDLEHCO_00890 1.2e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
JFDLEHCO_00891 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JFDLEHCO_00892 3e-267 ygaK C Berberine and berberine like
JFDLEHCO_00895 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
JFDLEHCO_00896 7.3e-188 S Amidohydrolase
JFDLEHCO_00897 1.4e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
JFDLEHCO_00898 4.8e-182 ssuA M Sulfonate ABC transporter
JFDLEHCO_00899 3.6e-146 ssuC P ABC transporter (permease)
JFDLEHCO_00900 1.4e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
JFDLEHCO_00901 1.2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JFDLEHCO_00902 3e-81 ygaO
JFDLEHCO_00903 4.8e-23 K Transcriptional regulator
JFDLEHCO_00905 1.6e-114 yhzB S B3/4 domain
JFDLEHCO_00906 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JFDLEHCO_00907 4.8e-176 yhbB S Putative amidase domain
JFDLEHCO_00908 6.9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JFDLEHCO_00909 3.5e-109 yhbD K Protein of unknown function (DUF4004)
JFDLEHCO_00910 8.6e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
JFDLEHCO_00911 3.5e-65 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
JFDLEHCO_00913 0.0 prkA T Ser protein kinase
JFDLEHCO_00914 1.2e-216 yhbH S Belongs to the UPF0229 family
JFDLEHCO_00915 4.6e-74 yhbI K DNA-binding transcription factor activity
JFDLEHCO_00916 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
JFDLEHCO_00917 6.4e-285 yhcA EGP Major facilitator Superfamily
JFDLEHCO_00918 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
JFDLEHCO_00919 3.8e-55 yhcC
JFDLEHCO_00920 9.6e-53
JFDLEHCO_00921 2.5e-62 yhcF K Transcriptional regulator
JFDLEHCO_00922 1.6e-126 yhcG V ABC transporter, ATP-binding protein
JFDLEHCO_00923 4.1e-167 yhcH V ABC transporter, ATP-binding protein
JFDLEHCO_00924 5.1e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JFDLEHCO_00925 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
JFDLEHCO_00926 3.5e-149 metQ M Belongs to the nlpA lipoprotein family
JFDLEHCO_00927 4.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
JFDLEHCO_00928 2.2e-222 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JFDLEHCO_00929 4.8e-57 yhcM
JFDLEHCO_00930 3.9e-85 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JFDLEHCO_00931 6e-163 yhcP
JFDLEHCO_00932 3.7e-117 yhcQ M Spore coat protein
JFDLEHCO_00933 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
JFDLEHCO_00934 1.6e-108 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
JFDLEHCO_00935 4.9e-173 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JFDLEHCO_00936 1.3e-69 yhcU S Family of unknown function (DUF5365)
JFDLEHCO_00937 2.6e-68 yhcV S COG0517 FOG CBS domain
JFDLEHCO_00938 4.9e-125 yhcW 5.4.2.6 S hydrolase
JFDLEHCO_00939 1.7e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JFDLEHCO_00940 1.7e-262 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JFDLEHCO_00941 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JFDLEHCO_00942 1.2e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
JFDLEHCO_00943 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JFDLEHCO_00944 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JFDLEHCO_00945 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
JFDLEHCO_00946 1.8e-209 yhcY 2.7.13.3 T Histidine kinase
JFDLEHCO_00947 1.5e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JFDLEHCO_00948 4.6e-91 azr 1.7.1.6 S NADPH-dependent FMN reductase
JFDLEHCO_00949 2.5e-39 yhdB S YhdB-like protein
JFDLEHCO_00950 1.1e-53 yhdC S Protein of unknown function (DUF3889)
JFDLEHCO_00951 1.6e-218 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JFDLEHCO_00952 1.9e-74 nsrR K Transcriptional regulator
JFDLEHCO_00953 1.4e-257 ygxB M Conserved TM helix
JFDLEHCO_00954 1.2e-271 ycgB S Stage V sporulation protein R
JFDLEHCO_00955 6.2e-260 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
JFDLEHCO_00956 3.3e-128 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JFDLEHCO_00957 9e-164 citR K Transcriptional regulator
JFDLEHCO_00958 1.3e-207 citA 2.3.3.1 C Belongs to the citrate synthase family
JFDLEHCO_00959 5.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JFDLEHCO_00960 4.1e-251 yhdG E amino acid
JFDLEHCO_00961 2e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
JFDLEHCO_00962 8.1e-45 yhdK S Sigma-M inhibitor protein
JFDLEHCO_00963 1.3e-201 yhdL S Sigma factor regulator N-terminal
JFDLEHCO_00964 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
JFDLEHCO_00965 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
JFDLEHCO_00966 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JFDLEHCO_00967 4.3e-71 cueR K transcriptional
JFDLEHCO_00968 3.5e-227 yhdR 2.6.1.1 E Aminotransferase
JFDLEHCO_00969 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JFDLEHCO_00970 2.9e-257 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
JFDLEHCO_00971 8.5e-52 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JFDLEHCO_00972 1.7e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JFDLEHCO_00973 2.8e-131 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JFDLEHCO_00975 1.6e-205 yhdY M Mechanosensitive ion channel
JFDLEHCO_00976 4.5e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
JFDLEHCO_00977 4.9e-159 yheN G deacetylase
JFDLEHCO_00978 4.3e-155 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
JFDLEHCO_00979 4.6e-88 pksA K Transcriptional regulator
JFDLEHCO_00980 1.2e-94 ymcC S Membrane
JFDLEHCO_00981 4.3e-86 T universal stress protein
JFDLEHCO_00983 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
JFDLEHCO_00984 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
JFDLEHCO_00985 1.1e-112 yheG GM NAD(P)H-binding
JFDLEHCO_00987 5.8e-29 sspB S spore protein
JFDLEHCO_00988 1.7e-36 yheE S Family of unknown function (DUF5342)
JFDLEHCO_00989 1.1e-261 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
JFDLEHCO_00990 4.8e-215 yheC HJ YheC/D like ATP-grasp
JFDLEHCO_00991 5.9e-208 yheB S Belongs to the UPF0754 family
JFDLEHCO_00992 4e-54 yheA S Belongs to the UPF0342 family
JFDLEHCO_00993 1.2e-205 yhaZ L DNA alkylation repair enzyme
JFDLEHCO_00994 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
JFDLEHCO_00995 9.3e-294 hemZ H coproporphyrinogen III oxidase
JFDLEHCO_00996 1.8e-253 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
JFDLEHCO_00997 2.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
JFDLEHCO_00998 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
JFDLEHCO_01000 2.5e-138 yhaR 5.3.3.18 I enoyl-CoA hydratase
JFDLEHCO_01001 7.3e-15 S YhzD-like protein
JFDLEHCO_01002 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
JFDLEHCO_01003 1.9e-207 yhaP CP COG1668 ABC-type Na efflux pump, permease component
JFDLEHCO_01004 9.1e-239 yhaO L DNA repair exonuclease
JFDLEHCO_01005 0.0 yhaN L AAA domain
JFDLEHCO_01006 9e-178 yhaM L Shows a 3'-5' exoribonuclease activity
JFDLEHCO_01007 1.6e-32 yhaL S Sporulation protein YhaL
JFDLEHCO_01008 3.3e-123 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JFDLEHCO_01009 7e-95 yhaK S Putative zincin peptidase
JFDLEHCO_01010 9.9e-55 yhaI S Protein of unknown function (DUF1878)
JFDLEHCO_01011 8.6e-113 hpr K Negative regulator of protease production and sporulation
JFDLEHCO_01012 6.2e-39 yhaH S YtxH-like protein
JFDLEHCO_01013 2e-17
JFDLEHCO_01014 2.9e-77 trpP S Tryptophan transporter TrpP
JFDLEHCO_01015 1.3e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JFDLEHCO_01016 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
JFDLEHCO_01017 1.1e-135 ecsA V transporter (ATP-binding protein)
JFDLEHCO_01018 1.7e-221 ecsB U ABC transporter
JFDLEHCO_01019 3e-125 ecsC S EcsC protein family
JFDLEHCO_01020 2.2e-226 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JFDLEHCO_01021 1.9e-245 yhfA C membrane
JFDLEHCO_01022 5.8e-91 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
JFDLEHCO_01023 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JFDLEHCO_01024 3e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JFDLEHCO_01025 2.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JFDLEHCO_01026 1.4e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JFDLEHCO_01027 3.2e-101 yhgD K Transcriptional regulator
JFDLEHCO_01028 6.5e-278 yhgE S YhgE Pip N-terminal domain protein
JFDLEHCO_01029 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JFDLEHCO_01031 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
JFDLEHCO_01032 3.4e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JFDLEHCO_01033 7.9e-11 yhfH S YhfH-like protein
JFDLEHCO_01034 1.5e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
JFDLEHCO_01035 3.1e-189 lplJ 6.3.1.20 H Lipoate-protein ligase
JFDLEHCO_01036 8.2e-114 yhfK GM NmrA-like family
JFDLEHCO_01037 6.2e-301 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
JFDLEHCO_01038 8.7e-66 yhfM
JFDLEHCO_01039 6e-238 yhfN 3.4.24.84 O Peptidase M48
JFDLEHCO_01040 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
JFDLEHCO_01041 1.6e-160 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
JFDLEHCO_01042 3.6e-105 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
JFDLEHCO_01043 3.8e-204 vraB 2.3.1.9 I Belongs to the thiolase family
JFDLEHCO_01044 5.4e-283 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
JFDLEHCO_01045 9.3e-90 bioY S BioY family
JFDLEHCO_01046 1e-200 hemAT NT chemotaxis protein
JFDLEHCO_01047 3.9e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
JFDLEHCO_01048 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JFDLEHCO_01049 1.3e-32 yhzC S IDEAL
JFDLEHCO_01050 1.9e-109 comK K Competence transcription factor
JFDLEHCO_01051 3.9e-68 frataxin S Domain of unknown function (DU1801)
JFDLEHCO_01052 3.9e-68 frataxin S Domain of unknown function (DU1801)
JFDLEHCO_01053 1.3e-93 mepB S MepB protein
JFDLEHCO_01054 1.9e-127 yrpD S Domain of unknown function, YrpD
JFDLEHCO_01055 1.6e-42 yhjA S Excalibur calcium-binding domain
JFDLEHCO_01056 3.9e-51 S Belongs to the UPF0145 family
JFDLEHCO_01057 1.3e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JFDLEHCO_01058 1.4e-27 yhjC S Protein of unknown function (DUF3311)
JFDLEHCO_01059 1.7e-60 yhjD
JFDLEHCO_01060 4.8e-111 yhjE S SNARE associated Golgi protein
JFDLEHCO_01061 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
JFDLEHCO_01062 3e-281 yhjG CH FAD binding domain
JFDLEHCO_01063 5.8e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
JFDLEHCO_01064 5.1e-191 abrB S membrane
JFDLEHCO_01065 1.1e-209 blt EGP Major facilitator Superfamily
JFDLEHCO_01066 4.5e-109 K QacR-like protein, C-terminal region
JFDLEHCO_01067 2.6e-94 yhjR S Rubrerythrin
JFDLEHCO_01068 1.6e-126 ydfS S Protein of unknown function (DUF421)
JFDLEHCO_01069 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
JFDLEHCO_01070 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JFDLEHCO_01071 3e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JFDLEHCO_01072 0.0 sbcC L COG0419 ATPase involved in DNA repair
JFDLEHCO_01073 1.3e-50 yisB V COG1403 Restriction endonuclease
JFDLEHCO_01074 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
JFDLEHCO_01075 1.9e-65 gerPE S Spore germination protein GerPE
JFDLEHCO_01076 3.1e-23 gerPD S Spore germination protein
JFDLEHCO_01077 1.4e-62 gerPC S Spore germination protein
JFDLEHCO_01078 6.2e-35 gerPB S cell differentiation
JFDLEHCO_01079 8.4e-34 gerPA S Spore germination protein
JFDLEHCO_01080 5e-07 yisI S Spo0E like sporulation regulatory protein
JFDLEHCO_01081 1.3e-173 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
JFDLEHCO_01082 1.1e-59 yisL S UPF0344 protein
JFDLEHCO_01083 1.3e-99 yisN S Protein of unknown function (DUF2777)
JFDLEHCO_01084 0.0 asnO 6.3.5.4 E Asparagine synthase
JFDLEHCO_01085 6.7e-136 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
JFDLEHCO_01086 1.5e-245 yisQ V Mate efflux family protein
JFDLEHCO_01087 6.3e-162 yisR K Transcriptional regulator
JFDLEHCO_01088 1.3e-90 yisT S DinB family
JFDLEHCO_01089 1.2e-72 mcbG S Pentapeptide repeats (9 copies)
JFDLEHCO_01090 6.2e-81 yjcF S Acetyltransferase (GNAT) domain
JFDLEHCO_01091 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
JFDLEHCO_01092 6.6e-55 yajQ S Belongs to the UPF0234 family
JFDLEHCO_01093 1.8e-161 cvfB S protein conserved in bacteria
JFDLEHCO_01094 6.7e-176 yufN S ABC transporter substrate-binding protein PnrA-like
JFDLEHCO_01095 1.8e-237 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
JFDLEHCO_01096 1.3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
JFDLEHCO_01098 1.3e-159 yitS S protein conserved in bacteria
JFDLEHCO_01099 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
JFDLEHCO_01100 2.9e-81 ipi S Intracellular proteinase inhibitor
JFDLEHCO_01101 4.4e-26 S Protein of unknown function (DUF3813)
JFDLEHCO_01102 3.5e-07
JFDLEHCO_01103 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JFDLEHCO_01104 4.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
JFDLEHCO_01105 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
JFDLEHCO_01106 2.2e-81 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
JFDLEHCO_01107 7.8e-274 yitY C D-arabinono-1,4-lactone oxidase
JFDLEHCO_01108 4.1e-90 norB G Major Facilitator Superfamily
JFDLEHCO_01109 1e-198 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JFDLEHCO_01110 7.2e-228 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JFDLEHCO_01111 1.5e-138 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
JFDLEHCO_01112 3.1e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
JFDLEHCO_01113 6.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JFDLEHCO_01114 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
JFDLEHCO_01115 4.2e-178 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JFDLEHCO_01116 1.2e-27 yjzC S YjzC-like protein
JFDLEHCO_01117 1.5e-23 yjzD S Protein of unknown function (DUF2929)
JFDLEHCO_01118 6.8e-141 yjaU I carboxylic ester hydrolase activity
JFDLEHCO_01119 1.5e-106 yjaV
JFDLEHCO_01120 1.9e-166 med S Transcriptional activator protein med
JFDLEHCO_01121 1.1e-26 comZ S ComZ
JFDLEHCO_01122 5.9e-32 yjzB
JFDLEHCO_01123 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JFDLEHCO_01124 8.9e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JFDLEHCO_01125 5.6e-149 yjaZ O Zn-dependent protease
JFDLEHCO_01126 3.3e-183 appD P Belongs to the ABC transporter superfamily
JFDLEHCO_01127 5.9e-188 appF E Belongs to the ABC transporter superfamily
JFDLEHCO_01128 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
JFDLEHCO_01129 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JFDLEHCO_01130 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JFDLEHCO_01131 5.5e-146 yjbA S Belongs to the UPF0736 family
JFDLEHCO_01132 8e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
JFDLEHCO_01133 0.0 oppA E ABC transporter substrate-binding protein
JFDLEHCO_01134 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JFDLEHCO_01135 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JFDLEHCO_01136 2.7e-202 oppD P Belongs to the ABC transporter superfamily
JFDLEHCO_01137 2.5e-172 oppF E Belongs to the ABC transporter superfamily
JFDLEHCO_01138 3.9e-234 S Putative glycosyl hydrolase domain
JFDLEHCO_01139 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JFDLEHCO_01140 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JFDLEHCO_01141 1.9e-110 yjbE P Integral membrane protein TerC family
JFDLEHCO_01142 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
JFDLEHCO_01143 3.5e-224 yjbF S Competence protein
JFDLEHCO_01144 0.0 pepF E oligoendopeptidase F
JFDLEHCO_01145 5.8e-19
JFDLEHCO_01146 7.8e-171 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
JFDLEHCO_01147 4.8e-72 yjbI S Bacterial-like globin
JFDLEHCO_01148 1.2e-118 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JFDLEHCO_01149 1.1e-101 yjbK S protein conserved in bacteria
JFDLEHCO_01150 1.6e-61 yjbL S Belongs to the UPF0738 family
JFDLEHCO_01151 2.3e-108 yjbM 2.7.6.5 S GTP pyrophosphokinase
JFDLEHCO_01152 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JFDLEHCO_01153 5.7e-166 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JFDLEHCO_01154 4.2e-146 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
JFDLEHCO_01155 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JFDLEHCO_01156 5.2e-138 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JFDLEHCO_01157 1.9e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
JFDLEHCO_01158 2.3e-220 thiO 1.4.3.19 E Glycine oxidase
JFDLEHCO_01159 1.4e-30 thiS H Thiamine biosynthesis
JFDLEHCO_01160 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
JFDLEHCO_01161 9.9e-191 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JFDLEHCO_01162 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JFDLEHCO_01163 1.4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
JFDLEHCO_01164 3e-89 yjbX S Spore coat protein
JFDLEHCO_01165 1e-83 cotZ S Spore coat protein
JFDLEHCO_01166 9.2e-94 cotY S Spore coat protein Z
JFDLEHCO_01167 1.5e-75 cotX S Spore Coat Protein X and V domain
JFDLEHCO_01168 1.1e-23 cotW
JFDLEHCO_01169 3.2e-57 cotV S Spore Coat Protein X and V domain
JFDLEHCO_01170 8.7e-57 yjcA S Protein of unknown function (DUF1360)
JFDLEHCO_01173 3.8e-38 spoVIF S Stage VI sporulation protein F
JFDLEHCO_01174 0.0 yjcD 3.6.4.12 L DNA helicase
JFDLEHCO_01175 1.2e-36
JFDLEHCO_01176 3.6e-145 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
JFDLEHCO_01177 2.3e-125 S ABC-2 type transporter
JFDLEHCO_01178 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
JFDLEHCO_01179 9.4e-36 K SpoVT / AbrB like domain
JFDLEHCO_01180 5e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JFDLEHCO_01181 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
JFDLEHCO_01182 5.5e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
JFDLEHCO_01183 5.4e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JFDLEHCO_01184 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JFDLEHCO_01186 8.7e-31
JFDLEHCO_01187 2.8e-255 yobL S Bacterial EndoU nuclease
JFDLEHCO_01189 5.9e-87
JFDLEHCO_01191 3.9e-13
JFDLEHCO_01193 8.2e-57
JFDLEHCO_01194 0.0 yobL S Bacterial EndoU nuclease
JFDLEHCO_01195 3.2e-95
JFDLEHCO_01198 2.4e-135
JFDLEHCO_01201 5.7e-169 bla 3.5.2.6 V beta-lactamase
JFDLEHCO_01202 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
JFDLEHCO_01203 1.6e-255 yfjF EGP Belongs to the major facilitator superfamily
JFDLEHCO_01204 7.9e-82 napB K helix_turn_helix multiple antibiotic resistance protein
JFDLEHCO_01205 8.3e-223 ganA 3.2.1.89 G arabinogalactan
JFDLEHCO_01206 3.2e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JFDLEHCO_01207 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JFDLEHCO_01208 9e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JFDLEHCO_01209 0.0 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JFDLEHCO_01210 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
JFDLEHCO_01211 7.3e-285 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
JFDLEHCO_01212 5.1e-139 lacR K COG1349 Transcriptional regulators of sugar metabolism
JFDLEHCO_01213 1.1e-127 5.4.2.6 S Haloacid dehalogenase-like hydrolase
JFDLEHCO_01214 1.5e-145 N Kelch motif
JFDLEHCO_01216 8.1e-106 yhiD S MgtC SapB transporter
JFDLEHCO_01218 7.5e-22 yjfB S Putative motility protein
JFDLEHCO_01219 2.6e-70 T PhoQ Sensor
JFDLEHCO_01220 1.7e-102 yjgB S Domain of unknown function (DUF4309)
JFDLEHCO_01221 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
JFDLEHCO_01222 4.3e-92 yjgD S Protein of unknown function (DUF1641)
JFDLEHCO_01223 4.2e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
JFDLEHCO_01224 3.6e-224 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
JFDLEHCO_01225 6.8e-29
JFDLEHCO_01226 5.9e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JFDLEHCO_01227 9.3e-125 ybbM S transport system, permease component
JFDLEHCO_01228 2.4e-133 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
JFDLEHCO_01229 1.7e-179 yjlA EG Putative multidrug resistance efflux transporter
JFDLEHCO_01230 6.1e-93 yjlB S Cupin domain
JFDLEHCO_01231 7e-66 yjlC S Protein of unknown function (DUF1641)
JFDLEHCO_01232 3.5e-219 yjlD 1.6.99.3 C NADH dehydrogenase
JFDLEHCO_01233 5.4e-280 uxaC 5.3.1.12 G glucuronate isomerase
JFDLEHCO_01234 3e-254 yjmB G symporter YjmB
JFDLEHCO_01235 3.4e-183 exuR K transcriptional
JFDLEHCO_01236 1.5e-285 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
JFDLEHCO_01237 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
JFDLEHCO_01238 3.9e-131 MA20_18170 S membrane transporter protein
JFDLEHCO_01239 7.3e-80 yjoA S DinB family
JFDLEHCO_01240 4.9e-215 S response regulator aspartate phosphatase
JFDLEHCO_01242 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JFDLEHCO_01243 4.7e-61 yjqA S Bacterial PH domain
JFDLEHCO_01244 2.5e-112 yjqB S phage-related replication protein
JFDLEHCO_01245 7.8e-111 xkdA E IrrE N-terminal-like domain
JFDLEHCO_01246 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
JFDLEHCO_01248 1.4e-17 xkdB K sequence-specific DNA binding
JFDLEHCO_01249 2.6e-154 xkdC L Bacterial dnaA protein
JFDLEHCO_01252 2e-10 yqaO S Phage-like element PBSX protein XtrA
JFDLEHCO_01253 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
JFDLEHCO_01254 2.1e-35 xtmA
JFDLEHCO_01255 1.4e-41
JFDLEHCO_01257 1.7e-30 xkdX
JFDLEHCO_01258 7.6e-143 xepA
JFDLEHCO_01259 8.7e-38 xhlA S Haemolysin XhlA
JFDLEHCO_01260 1.3e-38 xhlB S SPP1 phage holin
JFDLEHCO_01261 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JFDLEHCO_01262 8.7e-23 spoIISB S Stage II sporulation protein SB
JFDLEHCO_01263 7.5e-135 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
JFDLEHCO_01264 2e-175 pit P phosphate transporter
JFDLEHCO_01265 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
JFDLEHCO_01266 3.8e-243 steT E amino acid
JFDLEHCO_01267 5e-184 mhqA E COG0346 Lactoylglutathione lyase and related lyases
JFDLEHCO_01268 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JFDLEHCO_01269 3.4e-180 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JFDLEHCO_01271 2.7e-207 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JFDLEHCO_01272 3.2e-289 yubD P Major Facilitator Superfamily
JFDLEHCO_01274 6.5e-156 dppA E D-aminopeptidase
JFDLEHCO_01275 6.4e-160 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JFDLEHCO_01276 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JFDLEHCO_01277 5.4e-192 dppD P Belongs to the ABC transporter superfamily
JFDLEHCO_01278 0.0 dppE E ABC transporter substrate-binding protein
JFDLEHCO_01279 6.8e-178 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
JFDLEHCO_01280 1e-204 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
JFDLEHCO_01281 6.8e-175 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
JFDLEHCO_01282 1.5e-183 ykfD E Belongs to the ABC transporter superfamily
JFDLEHCO_01283 1.3e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
JFDLEHCO_01284 1.2e-160 ykgA E Amidinotransferase
JFDLEHCO_01285 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
JFDLEHCO_01286 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JFDLEHCO_01287 9.4e-53 ykkC P Multidrug resistance protein
JFDLEHCO_01288 3.4e-49 ykkD P Multidrug resistance protein
JFDLEHCO_01289 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
JFDLEHCO_01290 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JFDLEHCO_01291 3.6e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JFDLEHCO_01292 1.5e-71 ohrA O Organic hydroperoxide resistance protein
JFDLEHCO_01293 6.1e-88 ohrR K COG1846 Transcriptional regulators
JFDLEHCO_01294 4.2e-71 ohrB O Organic hydroperoxide resistance protein
JFDLEHCO_01295 9.5e-61 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JFDLEHCO_01297 8.1e-218 M Glycosyl transferase family 2
JFDLEHCO_01298 2.2e-135 M PFAM Collagen triple helix repeat (20 copies)
JFDLEHCO_01299 6.5e-218 hcaT 1.5.1.2 EGP Major facilitator Superfamily
JFDLEHCO_01300 4.1e-124 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
JFDLEHCO_01301 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JFDLEHCO_01302 1.2e-177 isp O Belongs to the peptidase S8 family
JFDLEHCO_01303 8.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JFDLEHCO_01304 9.3e-133 ykoC P Cobalt transport protein
JFDLEHCO_01305 0.0 P ABC transporter, ATP-binding protein
JFDLEHCO_01306 2.4e-99 ykoE S ABC-type cobalt transport system, permease component
JFDLEHCO_01307 1.2e-246 ydhD M Glycosyl hydrolase
JFDLEHCO_01309 2.2e-238 mgtE P Acts as a magnesium transporter
JFDLEHCO_01310 5.4e-53 tnrA K transcriptional
JFDLEHCO_01311 1.9e-16
JFDLEHCO_01312 3.1e-26 ykoL
JFDLEHCO_01313 1.1e-80 ykoM K transcriptional
JFDLEHCO_01314 2.2e-99 ykoP G polysaccharide deacetylase
JFDLEHCO_01315 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
JFDLEHCO_01316 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JFDLEHCO_01317 4.1e-101 ykoX S membrane-associated protein
JFDLEHCO_01318 9.2e-136 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
JFDLEHCO_01319 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JFDLEHCO_01320 8.1e-120 rsgI S Anti-sigma factor N-terminus
JFDLEHCO_01321 2.5e-26 sspD S small acid-soluble spore protein
JFDLEHCO_01322 2.7e-126 ykrK S Domain of unknown function (DUF1836)
JFDLEHCO_01323 4.1e-156 htpX O Belongs to the peptidase M48B family
JFDLEHCO_01324 4.3e-242 ktrB P COG0168 Trk-type K transport systems, membrane components
JFDLEHCO_01325 4.7e-116 ydfR S Protein of unknown function (DUF421)
JFDLEHCO_01326 7.9e-24 ykzE
JFDLEHCO_01327 8.2e-193 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
JFDLEHCO_01328 0.0 kinE 2.7.13.3 T Histidine kinase
JFDLEHCO_01329 2.4e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JFDLEHCO_01331 4.4e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JFDLEHCO_01332 1.2e-227 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JFDLEHCO_01333 1.2e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JFDLEHCO_01334 5.8e-230 mtnE 2.6.1.83 E Aminotransferase
JFDLEHCO_01335 2.5e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
JFDLEHCO_01336 4.4e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JFDLEHCO_01337 2.2e-116 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
JFDLEHCO_01338 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JFDLEHCO_01339 3.4e-10 S Spo0E like sporulation regulatory protein
JFDLEHCO_01340 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
JFDLEHCO_01341 1.5e-77 ykvE K transcriptional
JFDLEHCO_01342 2.7e-127 motB N Flagellar motor protein
JFDLEHCO_01343 1.1e-136 motA N flagellar motor
JFDLEHCO_01344 0.0 clpE O Belongs to the ClpA ClpB family
JFDLEHCO_01345 1.4e-184 ykvI S membrane
JFDLEHCO_01346 1.8e-193
JFDLEHCO_01347 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JFDLEHCO_01348 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
JFDLEHCO_01349 2.2e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
JFDLEHCO_01350 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JFDLEHCO_01352 1.5e-58 ykvN K Transcriptional regulator
JFDLEHCO_01353 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
JFDLEHCO_01354 1.4e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JFDLEHCO_01355 7e-46 ykvR S Protein of unknown function (DUF3219)
JFDLEHCO_01356 7.8e-25 ykvS S protein conserved in bacteria
JFDLEHCO_01357 6e-28
JFDLEHCO_01358 6.3e-111 ykvT 3.5.1.28 M Cell Wall Hydrolase
JFDLEHCO_01359 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JFDLEHCO_01360 1.1e-89 stoA CO thiol-disulfide
JFDLEHCO_01361 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
JFDLEHCO_01362 7.4e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
JFDLEHCO_01364 1.2e-177 ykvZ 5.1.1.1 K Transcriptional regulator
JFDLEHCO_01365 5.1e-156 glcT K antiterminator
JFDLEHCO_01366 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JFDLEHCO_01367 2.1e-39 ptsH G phosphocarrier protein HPr
JFDLEHCO_01368 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JFDLEHCO_01369 6.1e-38 splA S Transcriptional regulator
JFDLEHCO_01370 2.9e-190 splB 4.1.99.14 L Spore photoproduct lyase
JFDLEHCO_01371 4.4e-267 mcpC NT chemotaxis protein
JFDLEHCO_01372 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
JFDLEHCO_01373 7.2e-65
JFDLEHCO_01374 1.4e-120 ykwD J protein with SCP PR1 domains
JFDLEHCO_01375 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
JFDLEHCO_01376 2.6e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
JFDLEHCO_01377 1.3e-215 patA 2.6.1.1 E Aminotransferase
JFDLEHCO_01378 2.3e-09
JFDLEHCO_01379 3.7e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
JFDLEHCO_01380 1.4e-83 ykyB S YkyB-like protein
JFDLEHCO_01381 1.6e-241 ykuC EGP Major facilitator Superfamily
JFDLEHCO_01382 3.2e-89 ykuD S protein conserved in bacteria
JFDLEHCO_01383 3.8e-159 ykuE S Metallophosphoesterase
JFDLEHCO_01384 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JFDLEHCO_01385 1.5e-233 ykuI T Diguanylate phosphodiesterase
JFDLEHCO_01386 3.9e-37 ykuJ S protein conserved in bacteria
JFDLEHCO_01387 7.6e-94 ykuK S Ribonuclease H-like
JFDLEHCO_01388 2.5e-26 ykzF S Antirepressor AbbA
JFDLEHCO_01389 1e-75 ykuL S CBS domain
JFDLEHCO_01390 4.6e-168 ccpC K Transcriptional regulator
JFDLEHCO_01391 6.1e-90 fld C Flavodoxin
JFDLEHCO_01392 4.4e-174 ykuO
JFDLEHCO_01393 1.1e-80 fld C Flavodoxin
JFDLEHCO_01394 8.8e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JFDLEHCO_01395 5.3e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JFDLEHCO_01396 4.8e-38 ykuS S Belongs to the UPF0180 family
JFDLEHCO_01397 1.5e-141 ykuT M Mechanosensitive ion channel
JFDLEHCO_01398 7.7e-82 ykuV CO thiol-disulfide
JFDLEHCO_01399 1.5e-98 rok K Repressor of ComK
JFDLEHCO_01400 8.6e-163 yknT
JFDLEHCO_01401 3e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
JFDLEHCO_01402 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JFDLEHCO_01403 9.6e-247 moeA 2.10.1.1 H molybdopterin
JFDLEHCO_01404 2.6e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
JFDLEHCO_01405 7.1e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
JFDLEHCO_01406 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JFDLEHCO_01407 6.6e-109 yknW S Yip1 domain
JFDLEHCO_01408 1.4e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JFDLEHCO_01409 6.1e-123 macB V ABC transporter, ATP-binding protein
JFDLEHCO_01410 4.9e-213 yknZ V ABC transporter (permease)
JFDLEHCO_01411 1.1e-133 fruR K Transcriptional regulator
JFDLEHCO_01412 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
JFDLEHCO_01413 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
JFDLEHCO_01414 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JFDLEHCO_01415 8.9e-38 ykoA
JFDLEHCO_01416 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JFDLEHCO_01417 1.1e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JFDLEHCO_01418 4.5e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
JFDLEHCO_01419 7.2e-12 S Uncharacterized protein YkpC
JFDLEHCO_01420 6.9e-184 mreB D Rod-share determining protein MreBH
JFDLEHCO_01421 2.1e-45 abrB K of stationary sporulation gene expression
JFDLEHCO_01422 3.7e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
JFDLEHCO_01423 2.8e-151 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
JFDLEHCO_01424 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
JFDLEHCO_01425 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JFDLEHCO_01426 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JFDLEHCO_01427 8.2e-31 ykzG S Belongs to the UPF0356 family
JFDLEHCO_01428 1.6e-148 ykrA S hydrolases of the HAD superfamily
JFDLEHCO_01429 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JFDLEHCO_01431 8.1e-106 recN L Putative cell-wall binding lipoprotein
JFDLEHCO_01432 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JFDLEHCO_01433 0.0 Q Polyketide synthase of type I
JFDLEHCO_01434 0.0 Q polyketide synthase
JFDLEHCO_01435 0.0 Q Polyketide synthase of type I
JFDLEHCO_01436 0.0 Q Polyketide synthase of type I
JFDLEHCO_01437 0.0 Q Polyketide synthase of type I
JFDLEHCO_01438 0.0 Q Polyketide synthase of type I
JFDLEHCO_01439 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
JFDLEHCO_01440 1.2e-213 V Beta-lactamase
JFDLEHCO_01441 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JFDLEHCO_01442 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JFDLEHCO_01443 3.4e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JFDLEHCO_01444 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JFDLEHCO_01445 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
JFDLEHCO_01446 4.4e-141 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
JFDLEHCO_01447 3.1e-278 speA 4.1.1.19 E Arginine
JFDLEHCO_01448 1.6e-42 yktA S Belongs to the UPF0223 family
JFDLEHCO_01449 4.9e-119 yktB S Belongs to the UPF0637 family
JFDLEHCO_01450 9.7e-25 ykzI
JFDLEHCO_01451 4.2e-152 suhB 3.1.3.25 G Inositol monophosphatase
JFDLEHCO_01452 1.8e-83 ykzC S Acetyltransferase (GNAT) family
JFDLEHCO_01453 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
JFDLEHCO_01454 4.3e-200 ylaA
JFDLEHCO_01455 5e-142
JFDLEHCO_01456 8.9e-46 ylaB
JFDLEHCO_01457 2.2e-93 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
JFDLEHCO_01458 9.8e-14 sigC S Putative zinc-finger
JFDLEHCO_01459 4.4e-40 ylaE
JFDLEHCO_01460 6.7e-24 S Family of unknown function (DUF5325)
JFDLEHCO_01461 0.0 typA T GTP-binding protein TypA
JFDLEHCO_01462 1.3e-48 ylaH S YlaH-like protein
JFDLEHCO_01463 1e-33 ylaI S protein conserved in bacteria
JFDLEHCO_01464 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JFDLEHCO_01465 5.8e-247 phoH T ATPase related to phosphate starvation-inducible protein PhoH
JFDLEHCO_01466 7.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JFDLEHCO_01467 1.8e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
JFDLEHCO_01468 8.7e-44 ylaN S Belongs to the UPF0358 family
JFDLEHCO_01469 9e-215 ftsW D Belongs to the SEDS family
JFDLEHCO_01470 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JFDLEHCO_01471 2e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
JFDLEHCO_01472 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
JFDLEHCO_01473 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
JFDLEHCO_01474 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JFDLEHCO_01475 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
JFDLEHCO_01476 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
JFDLEHCO_01477 1.1e-166 ctaG S cytochrome c oxidase
JFDLEHCO_01478 5.9e-61 ylbA S YugN-like family
JFDLEHCO_01479 2.2e-73 ylbB T COG0517 FOG CBS domain
JFDLEHCO_01480 2.1e-199 ylbC S protein with SCP PR1 domains
JFDLEHCO_01481 4.5e-57 ylbD S Putative coat protein
JFDLEHCO_01482 8.8e-37 ylbE S YlbE-like protein
JFDLEHCO_01483 1.2e-71 ylbF S Belongs to the UPF0342 family
JFDLEHCO_01484 5.5e-43 ylbG S UPF0298 protein
JFDLEHCO_01486 8.5e-90 rsmD 2.1.1.171 L Methyltransferase
JFDLEHCO_01487 1.1e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JFDLEHCO_01488 2e-217 ylbJ S Sporulation integral membrane protein YlbJ
JFDLEHCO_01489 8.9e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
JFDLEHCO_01490 5.5e-189 ylbL T Belongs to the peptidase S16 family
JFDLEHCO_01491 1.4e-231 ylbM S Belongs to the UPF0348 family
JFDLEHCO_01492 2.7e-91 yceD S metal-binding, possibly nucleic acid-binding protein
JFDLEHCO_01493 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JFDLEHCO_01494 1.2e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
JFDLEHCO_01495 8.1e-90 ylbP K n-acetyltransferase
JFDLEHCO_01496 3.5e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JFDLEHCO_01497 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JFDLEHCO_01498 8.9e-78 mraZ K Belongs to the MraZ family
JFDLEHCO_01499 5.1e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JFDLEHCO_01500 2.9e-52 ftsL D Essential cell division protein
JFDLEHCO_01501 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
JFDLEHCO_01502 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
JFDLEHCO_01503 1.4e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JFDLEHCO_01504 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JFDLEHCO_01505 1.2e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JFDLEHCO_01506 2.2e-185 spoVE D Belongs to the SEDS family
JFDLEHCO_01507 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JFDLEHCO_01508 5.6e-169 murB 1.3.1.98 M cell wall formation
JFDLEHCO_01509 1.3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JFDLEHCO_01510 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JFDLEHCO_01511 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JFDLEHCO_01513 0.0 bpr O COG1404 Subtilisin-like serine proteases
JFDLEHCO_01514 4e-162 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
JFDLEHCO_01515 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JFDLEHCO_01516 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JFDLEHCO_01517 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
JFDLEHCO_01518 2.7e-257 argE 3.5.1.16 E Acetylornithine deacetylase
JFDLEHCO_01519 2.2e-38 ylmC S sporulation protein
JFDLEHCO_01520 1e-161 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
JFDLEHCO_01521 2.5e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JFDLEHCO_01522 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JFDLEHCO_01523 5.2e-41 yggT S membrane
JFDLEHCO_01524 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
JFDLEHCO_01525 8.9e-68 divIVA D Cell division initiation protein
JFDLEHCO_01526 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JFDLEHCO_01527 6.2e-66 dksA T COG1734 DnaK suppressor protein
JFDLEHCO_01528 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JFDLEHCO_01529 4.6e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JFDLEHCO_01530 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JFDLEHCO_01531 3.6e-233 pyrP F Xanthine uracil
JFDLEHCO_01532 1.5e-169 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JFDLEHCO_01533 4.9e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JFDLEHCO_01534 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JFDLEHCO_01535 0.0 carB 6.3.5.5 F Belongs to the CarB family
JFDLEHCO_01536 8.2e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
JFDLEHCO_01537 1.9e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JFDLEHCO_01538 4.2e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JFDLEHCO_01539 3.8e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JFDLEHCO_01541 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
JFDLEHCO_01542 1.8e-179 cysP P phosphate transporter
JFDLEHCO_01543 2.7e-224 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
JFDLEHCO_01544 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
JFDLEHCO_01545 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
JFDLEHCO_01546 3.4e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
JFDLEHCO_01547 1.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
JFDLEHCO_01548 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
JFDLEHCO_01549 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
JFDLEHCO_01550 7.7e-155 yloC S stress-induced protein
JFDLEHCO_01551 1.5e-40 ylzA S Belongs to the UPF0296 family
JFDLEHCO_01552 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JFDLEHCO_01553 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
JFDLEHCO_01554 2.3e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JFDLEHCO_01555 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JFDLEHCO_01556 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JFDLEHCO_01557 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JFDLEHCO_01558 4.2e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JFDLEHCO_01559 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
JFDLEHCO_01560 9.3e-141 stp 3.1.3.16 T phosphatase
JFDLEHCO_01561 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
JFDLEHCO_01562 5.7e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JFDLEHCO_01563 9.4e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JFDLEHCO_01564 1.4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
JFDLEHCO_01565 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JFDLEHCO_01566 5.5e-59 asp S protein conserved in bacteria
JFDLEHCO_01567 3.4e-305 yloV S kinase related to dihydroxyacetone kinase
JFDLEHCO_01568 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
JFDLEHCO_01569 7.1e-156 sdaAA 4.3.1.17 E L-serine dehydratase
JFDLEHCO_01570 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JFDLEHCO_01571 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
JFDLEHCO_01572 1.2e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JFDLEHCO_01573 4.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JFDLEHCO_01574 4.6e-129 IQ reductase
JFDLEHCO_01575 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JFDLEHCO_01576 1.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JFDLEHCO_01577 0.0 smc D Required for chromosome condensation and partitioning
JFDLEHCO_01578 4.4e-175 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JFDLEHCO_01579 9.1e-144 S Phosphotransferase enzyme family
JFDLEHCO_01580 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JFDLEHCO_01581 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JFDLEHCO_01582 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JFDLEHCO_01583 1.7e-35 ylqC S Belongs to the UPF0109 family
JFDLEHCO_01584 1.3e-61 ylqD S YlqD protein
JFDLEHCO_01585 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JFDLEHCO_01586 2.9e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JFDLEHCO_01587 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JFDLEHCO_01588 6.4e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JFDLEHCO_01589 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JFDLEHCO_01590 0.0 ylqG
JFDLEHCO_01591 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
JFDLEHCO_01592 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
JFDLEHCO_01593 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JFDLEHCO_01594 1.9e-172 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
JFDLEHCO_01595 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JFDLEHCO_01596 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JFDLEHCO_01597 7.2e-172 xerC L tyrosine recombinase XerC
JFDLEHCO_01598 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JFDLEHCO_01599 1.6e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JFDLEHCO_01600 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JFDLEHCO_01601 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
JFDLEHCO_01602 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
JFDLEHCO_01603 2.5e-31 fliE N Flagellar hook-basal body
JFDLEHCO_01604 1.4e-263 fliF N The M ring may be actively involved in energy transduction
JFDLEHCO_01605 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
JFDLEHCO_01606 1.3e-91 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
JFDLEHCO_01607 5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
JFDLEHCO_01608 4.5e-71 fliJ N Flagellar biosynthesis chaperone
JFDLEHCO_01609 4.4e-48 ylxF S MgtE intracellular N domain
JFDLEHCO_01610 1.8e-208 fliK N Flagellar hook-length control protein
JFDLEHCO_01611 4.8e-73 flgD N Flagellar basal body rod modification protein
JFDLEHCO_01612 4e-139 flgG N Flagellar basal body rod
JFDLEHCO_01613 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
JFDLEHCO_01614 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
JFDLEHCO_01615 1.9e-190 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JFDLEHCO_01616 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
JFDLEHCO_01617 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
JFDLEHCO_01618 4.3e-110 fliP N Plays a role in the flagellum-specific transport system
JFDLEHCO_01619 2e-37 fliQ N Role in flagellar biosynthesis
JFDLEHCO_01620 4e-131 fliR N Flagellar biosynthetic protein FliR
JFDLEHCO_01621 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JFDLEHCO_01622 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JFDLEHCO_01623 1.9e-195 flhF N Flagellar biosynthesis regulator FlhF
JFDLEHCO_01624 7.5e-158 flhG D Belongs to the ParA family
JFDLEHCO_01625 1.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
JFDLEHCO_01626 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
JFDLEHCO_01627 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
JFDLEHCO_01628 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
JFDLEHCO_01629 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
JFDLEHCO_01630 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JFDLEHCO_01631 8.1e-55 ylxL
JFDLEHCO_01632 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
JFDLEHCO_01633 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JFDLEHCO_01634 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JFDLEHCO_01635 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JFDLEHCO_01636 2.2e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JFDLEHCO_01637 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
JFDLEHCO_01638 2e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
JFDLEHCO_01639 3.1e-234 rasP M zinc metalloprotease
JFDLEHCO_01640 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JFDLEHCO_01641 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JFDLEHCO_01642 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
JFDLEHCO_01643 5.4e-206 nusA K Participates in both transcription termination and antitermination
JFDLEHCO_01644 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
JFDLEHCO_01645 1.8e-47 ylxQ J ribosomal protein
JFDLEHCO_01646 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JFDLEHCO_01647 3.9e-44 ylxP S protein conserved in bacteria
JFDLEHCO_01648 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JFDLEHCO_01649 8.6e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JFDLEHCO_01650 9.3e-183 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JFDLEHCO_01651 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JFDLEHCO_01652 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
JFDLEHCO_01653 8e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
JFDLEHCO_01654 3.6e-235 pepR S Belongs to the peptidase M16 family
JFDLEHCO_01655 2.6e-42 ymxH S YlmC YmxH family
JFDLEHCO_01656 1.1e-161 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
JFDLEHCO_01657 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
JFDLEHCO_01658 2.6e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JFDLEHCO_01659 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
JFDLEHCO_01660 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JFDLEHCO_01661 5.2e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JFDLEHCO_01662 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
JFDLEHCO_01663 6.3e-31 S YlzJ-like protein
JFDLEHCO_01664 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JFDLEHCO_01665 1.8e-133 ymfC K Transcriptional regulator
JFDLEHCO_01666 1.7e-230 ymfD EGP Major facilitator Superfamily
JFDLEHCO_01667 1.3e-76 K helix_turn_helix multiple antibiotic resistance protein
JFDLEHCO_01668 0.0 ydgH S drug exporters of the RND superfamily
JFDLEHCO_01669 1.2e-238 ymfF S Peptidase M16
JFDLEHCO_01670 2.3e-245 ymfH S zinc protease
JFDLEHCO_01671 1.6e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
JFDLEHCO_01672 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
JFDLEHCO_01673 3.5e-143 ymfK S Protein of unknown function (DUF3388)
JFDLEHCO_01674 4.8e-128 ymfM S protein conserved in bacteria
JFDLEHCO_01675 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JFDLEHCO_01676 1.7e-232 cinA 3.5.1.42 S Belongs to the CinA family
JFDLEHCO_01677 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JFDLEHCO_01678 1.3e-194 pbpX V Beta-lactamase
JFDLEHCO_01679 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
JFDLEHCO_01680 4.9e-153 ymdB S protein conserved in bacteria
JFDLEHCO_01681 1.2e-36 spoVS S Stage V sporulation protein S
JFDLEHCO_01682 1.6e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
JFDLEHCO_01683 6.1e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
JFDLEHCO_01684 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JFDLEHCO_01685 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
JFDLEHCO_01686 1.7e-88 cotE S Spore coat protein
JFDLEHCO_01687 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JFDLEHCO_01688 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JFDLEHCO_01690 3.9e-130 pksB 3.1.2.6 S Polyketide biosynthesis
JFDLEHCO_01691 6.8e-164 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JFDLEHCO_01692 3.9e-184 pksD Q Acyl transferase domain
JFDLEHCO_01693 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JFDLEHCO_01694 1.3e-35 acpK IQ Phosphopantetheine attachment site
JFDLEHCO_01695 1.3e-245 pksG 2.3.3.10 I synthase
JFDLEHCO_01696 4.8e-145 pksH 4.2.1.18 I enoyl-CoA hydratase
JFDLEHCO_01697 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
JFDLEHCO_01698 0.0 rhiB IQ polyketide synthase
JFDLEHCO_01699 0.0 Q Polyketide synthase of type I
JFDLEHCO_01700 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
JFDLEHCO_01701 0.0 dhbF IQ polyketide synthase
JFDLEHCO_01702 0.0 pks13 HQ Beta-ketoacyl synthase
JFDLEHCO_01703 2.8e-232 cypA C Cytochrome P450
JFDLEHCO_01704 7.5e-79 nucB M Deoxyribonuclease NucA/NucB
JFDLEHCO_01705 9.4e-119 yoaK S Membrane
JFDLEHCO_01706 1.4e-62 ymzB
JFDLEHCO_01707 4.7e-257 aprX O Belongs to the peptidase S8 family
JFDLEHCO_01709 1.4e-127 ymaC S Replication protein
JFDLEHCO_01710 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
JFDLEHCO_01711 5.2e-54 ebrB P Small Multidrug Resistance protein
JFDLEHCO_01712 3.1e-48 ebrA P Small Multidrug Resistance protein
JFDLEHCO_01714 1.4e-47 ymaF S YmaF family
JFDLEHCO_01715 6.7e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JFDLEHCO_01716 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
JFDLEHCO_01717 2.2e-44
JFDLEHCO_01718 1.8e-20 ymzA
JFDLEHCO_01719 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
JFDLEHCO_01720 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JFDLEHCO_01721 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JFDLEHCO_01722 2.4e-110 ymaB S MutT family
JFDLEHCO_01723 1.9e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JFDLEHCO_01724 1.3e-176 spoVK O stage V sporulation protein K
JFDLEHCO_01725 2.2e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JFDLEHCO_01726 5.7e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
JFDLEHCO_01727 4.3e-68 glnR K transcriptional
JFDLEHCO_01728 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
JFDLEHCO_01729 1e-08 L Belongs to the 'phage' integrase family
JFDLEHCO_01730 2.6e-15
JFDLEHCO_01731 2.9e-95
JFDLEHCO_01733 7.4e-216 mrjp G Major royal jelly protein
JFDLEHCO_01734 6.7e-254 xynT G MFS/sugar transport protein
JFDLEHCO_01735 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
JFDLEHCO_01736 8.3e-218 xylR GK ROK family
JFDLEHCO_01737 2.6e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
JFDLEHCO_01738 2.1e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
JFDLEHCO_01739 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
JFDLEHCO_01744 5.4e-17
JFDLEHCO_01745 4e-56 dinB S DinB family
JFDLEHCO_01746 3.5e-188 adhP 1.1.1.1 C alcohol dehydrogenase
JFDLEHCO_01748 2.1e-148 yoaP 3.1.3.18 K YoaP-like
JFDLEHCO_01749 1.3e-101 J Acetyltransferase (GNAT) domain
JFDLEHCO_01750 4.3e-69
JFDLEHCO_01752 1.7e-121 ynaE S Domain of unknown function (DUF3885)
JFDLEHCO_01753 5.4e-203 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JFDLEHCO_01754 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
JFDLEHCO_01756 2.4e-95 yvgO
JFDLEHCO_01758 0.0 yobO M Pectate lyase superfamily protein
JFDLEHCO_01759 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
JFDLEHCO_01760 1.4e-150 yndL S Replication protein
JFDLEHCO_01761 1.6e-07
JFDLEHCO_01762 1.2e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
JFDLEHCO_01763 1.1e-72 yndM S Protein of unknown function (DUF2512)
JFDLEHCO_01764 2.1e-12 yoaW
JFDLEHCO_01765 2.4e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JFDLEHCO_01766 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
JFDLEHCO_01767 3.5e-112 yneB L resolvase
JFDLEHCO_01768 9.8e-33 ynzC S UPF0291 protein
JFDLEHCO_01769 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JFDLEHCO_01770 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
JFDLEHCO_01771 2.3e-28 yneF S UPF0154 protein
JFDLEHCO_01772 2.1e-23 ynzD S Spo0E like sporulation regulatory protein
JFDLEHCO_01773 1.3e-125 ccdA O cytochrome c biogenesis protein
JFDLEHCO_01774 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
JFDLEHCO_01775 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
JFDLEHCO_01776 8.5e-75 yneK S Protein of unknown function (DUF2621)
JFDLEHCO_01777 1e-63 hspX O Spore coat protein
JFDLEHCO_01778 2.3e-19 sspP S Belongs to the SspP family
JFDLEHCO_01779 7.5e-15 sspO S Belongs to the SspO family
JFDLEHCO_01780 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JFDLEHCO_01781 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JFDLEHCO_01783 2.7e-33 tlp S Belongs to the Tlp family
JFDLEHCO_01784 1.3e-75 yneP S Thioesterase-like superfamily
JFDLEHCO_01785 4.4e-54 yneQ
JFDLEHCO_01786 1.3e-50 yneR S Belongs to the HesB IscA family
JFDLEHCO_01787 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JFDLEHCO_01788 1.5e-68 yccU S CoA-binding protein
JFDLEHCO_01789 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JFDLEHCO_01790 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JFDLEHCO_01791 1.2e-13
JFDLEHCO_01792 5.1e-41 ynfC
JFDLEHCO_01793 2.2e-252 agcS E Sodium alanine symporter
JFDLEHCO_01794 5e-184 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
JFDLEHCO_01795 7.2e-197 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
JFDLEHCO_01796 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
JFDLEHCO_01797 9.5e-216 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
JFDLEHCO_01798 9.8e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JFDLEHCO_01799 4.4e-183 kdgR_1 K transcriptional
JFDLEHCO_01800 5.4e-226 exuT G Sugar (and other) transporter
JFDLEHCO_01801 4.3e-160 yndG S DoxX-like family
JFDLEHCO_01802 3.4e-41 yndH S Domain of unknown function (DUF4166)
JFDLEHCO_01803 2.3e-311 yndJ S YndJ-like protein
JFDLEHCO_01805 1.4e-220 S Platelet-activating factor acetylhydrolase, isoform II
JFDLEHCO_01806 1.9e-299 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
JFDLEHCO_01807 5.6e-52 S Domain of unknown function (DUF4870)
JFDLEHCO_01808 6.7e-238 T PhoQ Sensor
JFDLEHCO_01809 5.2e-130 T Transcriptional regulatory protein, C terminal
JFDLEHCO_01810 1.8e-253 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
JFDLEHCO_01811 4.7e-301 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
JFDLEHCO_01812 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_01813 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_01814 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_01815 2.7e-227 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JFDLEHCO_01816 8.1e-140 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
JFDLEHCO_01817 1.9e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
JFDLEHCO_01818 3.4e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JFDLEHCO_01819 1.3e-257 yxjC EG COG2610 H gluconate symporter and related permeases
JFDLEHCO_01820 7.8e-227 bioI 1.14.14.46 C Cytochrome P450
JFDLEHCO_01821 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JFDLEHCO_01822 1.4e-130 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JFDLEHCO_01823 1.7e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
JFDLEHCO_01824 1.9e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
JFDLEHCO_01825 5.5e-149 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
JFDLEHCO_01826 1.7e-72 yngA S membrane
JFDLEHCO_01827 1.4e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JFDLEHCO_01828 3.2e-104 yngC S SNARE associated Golgi protein
JFDLEHCO_01829 2.6e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
JFDLEHCO_01830 8e-140 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
JFDLEHCO_01831 5e-170 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
JFDLEHCO_01832 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
JFDLEHCO_01833 4.9e-254 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
JFDLEHCO_01834 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JFDLEHCO_01835 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
JFDLEHCO_01836 3.2e-310 yngK T Glycosyl hydrolase-like 10
JFDLEHCO_01837 4.1e-65 yngL S Protein of unknown function (DUF1360)
JFDLEHCO_01838 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
JFDLEHCO_01839 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_01840 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_01841 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_01842 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_01843 1.6e-274 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
JFDLEHCO_01844 1.1e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
JFDLEHCO_01845 2.7e-247 yoeA V MATE efflux family protein
JFDLEHCO_01846 1.8e-98 yoeB S IseA DL-endopeptidase inhibitor
JFDLEHCO_01848 3.5e-97 L Integrase
JFDLEHCO_01849 1.8e-34 yoeD G Helix-turn-helix domain
JFDLEHCO_01850 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
JFDLEHCO_01851 1.1e-201 ybcL EGP Major facilitator Superfamily
JFDLEHCO_01852 1.8e-50 ybzH K Helix-turn-helix domain
JFDLEHCO_01854 2.3e-159 gltR1 K Transcriptional regulator
JFDLEHCO_01855 5.3e-189 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
JFDLEHCO_01856 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
JFDLEHCO_01857 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
JFDLEHCO_01858 3.3e-153 gltC K Transcriptional regulator
JFDLEHCO_01859 1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JFDLEHCO_01860 2e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JFDLEHCO_01861 1e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
JFDLEHCO_01862 1.1e-77 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
JFDLEHCO_01863 6.3e-45 L Transposase
JFDLEHCO_01864 2e-138 IQ Enoyl-(Acyl carrier protein) reductase
JFDLEHCO_01865 6e-227 K helix_turn_helix, arabinose operon control protein
JFDLEHCO_01866 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JFDLEHCO_01867 2.1e-43 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JFDLEHCO_01868 6.4e-142 yoxB
JFDLEHCO_01869 2.2e-203 yoaB EGP Major facilitator Superfamily
JFDLEHCO_01870 1.1e-280 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
JFDLEHCO_01871 3.9e-195 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JFDLEHCO_01872 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JFDLEHCO_01873 6.2e-16 yoaF
JFDLEHCO_01875 7.1e-101 hpr K helix_turn_helix multiple antibiotic resistance protein
JFDLEHCO_01876 1.6e-45
JFDLEHCO_01877 2.5e-88 S SMI1-KNR4 cell-wall
JFDLEHCO_01878 0.0 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
JFDLEHCO_01879 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
JFDLEHCO_01880 7.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
JFDLEHCO_01881 7.5e-95 yobS K Transcriptional regulator
JFDLEHCO_01882 4.5e-137 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
JFDLEHCO_01883 1.9e-92 yobW
JFDLEHCO_01884 3.4e-55 czrA K transcriptional
JFDLEHCO_01885 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JFDLEHCO_01886 2.8e-91 yozB S membrane
JFDLEHCO_01887 5.4e-144 yocB J Protein required for attachment to host cells
JFDLEHCO_01888 1.9e-94 yocC
JFDLEHCO_01889 5.3e-189 yocD 3.4.17.13 V peptidase S66
JFDLEHCO_01891 2.5e-118 yocH CBM50 M COG1388 FOG LysM repeat
JFDLEHCO_01892 0.0 recQ 3.6.4.12 L DNA helicase
JFDLEHCO_01893 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JFDLEHCO_01895 3e-60 dksA T general stress protein
JFDLEHCO_01896 7.8e-10 yocL
JFDLEHCO_01897 1.7e-08
JFDLEHCO_01898 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
JFDLEHCO_01899 3.8e-44 yozN
JFDLEHCO_01900 8.5e-37 yocN
JFDLEHCO_01901 2.4e-56 yozO S Bacterial PH domain
JFDLEHCO_01903 1.6e-31 yozC
JFDLEHCO_01904 1.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
JFDLEHCO_01905 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
JFDLEHCO_01906 3.8e-167 sodA 1.15.1.1 P Superoxide dismutase
JFDLEHCO_01907 3e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
JFDLEHCO_01908 5.8e-164 yocS S -transporter
JFDLEHCO_01909 5.1e-144 S Metallo-beta-lactamase superfamily
JFDLEHCO_01910 5.5e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
JFDLEHCO_01911 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
JFDLEHCO_01912 0.0 yojO P Von Willebrand factor
JFDLEHCO_01913 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
JFDLEHCO_01914 2e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JFDLEHCO_01915 1e-229 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JFDLEHCO_01916 3e-226 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
JFDLEHCO_01917 7.4e-112 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JFDLEHCO_01919 5.9e-247 norM V Multidrug efflux pump
JFDLEHCO_01920 4.5e-152 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JFDLEHCO_01921 2.5e-126 yojG S deacetylase
JFDLEHCO_01922 9.7e-61 yojF S Protein of unknown function (DUF1806)
JFDLEHCO_01923 4.9e-23
JFDLEHCO_01924 9.2e-164 rarD S -transporter
JFDLEHCO_01925 1.3e-81 yozR S COG0071 Molecular chaperone (small heat shock protein)
JFDLEHCO_01927 1.6e-67 yodA S tautomerase
JFDLEHCO_01928 1.4e-70 yoaQ S Evidence 4 Homologs of previously reported genes of
JFDLEHCO_01929 1.4e-56 yodB K transcriptional
JFDLEHCO_01930 1.2e-106 yodC C nitroreductase
JFDLEHCO_01931 2.7e-111 mhqD S Carboxylesterase
JFDLEHCO_01932 9.7e-177 yodE E COG0346 Lactoylglutathione lyase and related lyases
JFDLEHCO_01933 1.4e-19 S Protein of unknown function (DUF3311)
JFDLEHCO_01934 3.5e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JFDLEHCO_01935 7.4e-288 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
JFDLEHCO_01936 1.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JFDLEHCO_01937 5.2e-133 yydK K Transcriptional regulator
JFDLEHCO_01938 4.2e-256 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
JFDLEHCO_01939 8.9e-130 yodH Q Methyltransferase
JFDLEHCO_01940 1.1e-34 yodI
JFDLEHCO_01941 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
JFDLEHCO_01942 9.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
JFDLEHCO_01944 8.6e-56 yodL S YodL-like
JFDLEHCO_01945 5e-105 yodM 3.6.1.27 I Acid phosphatase homologues
JFDLEHCO_01946 6.2e-24 yozD S YozD-like protein
JFDLEHCO_01948 1.7e-125 yodN
JFDLEHCO_01949 4.1e-36 yozE S Belongs to the UPF0346 family
JFDLEHCO_01950 8.3e-47 yokU S YokU-like protein, putative antitoxin
JFDLEHCO_01951 3.2e-280 kamA 5.4.3.2 E lysine 2,3-aminomutase
JFDLEHCO_01952 1.4e-161 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
JFDLEHCO_01953 1.8e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
JFDLEHCO_01954 1.2e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
JFDLEHCO_01955 5.8e-126 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JFDLEHCO_01956 2.1e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JFDLEHCO_01958 4e-147 yiiD K acetyltransferase
JFDLEHCO_01959 4.4e-252 cgeD M maturation of the outermost layer of the spore
JFDLEHCO_01960 1e-42 cgeC
JFDLEHCO_01961 9.8e-55 cgeA
JFDLEHCO_01962 1.5e-183 cgeB S Spore maturation protein
JFDLEHCO_01963 6.6e-223 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
JFDLEHCO_01964 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
JFDLEHCO_01968 1.4e-212 S aspartate phosphatase
JFDLEHCO_01969 7.1e-89 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JFDLEHCO_01970 1.7e-276 baeB 3.1.2.6, 3.4.21.102 P Rhodanese Homology Domain
JFDLEHCO_01971 8.3e-229 fccB 1.8.5.4 S Pyridine nucleotide-disulphide oxidoreductase
JFDLEHCO_01972 1.5e-98 nreC T helix_turn_helix, Lux Regulon
JFDLEHCO_01973 4.7e-199 2.7.13.3 T Histidine kinase
JFDLEHCO_01974 1.8e-84 yrkJ S response to heat
JFDLEHCO_01976 5.6e-103 yokK S SMI1 / KNR4 family
JFDLEHCO_01977 2.5e-129 S A nuclease of the HNH/ENDO VII superfamily with conserved WHH
JFDLEHCO_01978 0.0 yokA L Recombinase
JFDLEHCO_01979 1.4e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
JFDLEHCO_01980 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
JFDLEHCO_01981 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JFDLEHCO_01982 4.7e-67 ypoP K transcriptional
JFDLEHCO_01983 5.5e-98 ypmS S protein conserved in bacteria
JFDLEHCO_01984 4e-136 ypmR E GDSL-like Lipase/Acylhydrolase
JFDLEHCO_01985 1e-116 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
JFDLEHCO_01986 2.6e-39 ypmP S Protein of unknown function (DUF2535)
JFDLEHCO_01987 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JFDLEHCO_01988 4.1e-181 pspF K Transcriptional regulator
JFDLEHCO_01989 9.3e-110 hlyIII S protein, Hemolysin III
JFDLEHCO_01990 5e-116 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
JFDLEHCO_01991 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JFDLEHCO_01992 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JFDLEHCO_01993 2.7e-114 ypjP S YpjP-like protein
JFDLEHCO_01994 2.7e-132 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
JFDLEHCO_01995 1e-75 yphP S Belongs to the UPF0403 family
JFDLEHCO_01996 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JFDLEHCO_01997 6.6e-159 ypgR C COG0694 Thioredoxin-like proteins and domains
JFDLEHCO_01998 1.5e-101 ypgQ S phosphohydrolase
JFDLEHCO_01999 1.1e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
JFDLEHCO_02000 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JFDLEHCO_02001 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
JFDLEHCO_02002 1e-30 cspD K Cold-shock protein
JFDLEHCO_02003 3.3e-12 degR
JFDLEHCO_02004 7.2e-37 S Protein of unknown function (DUF2564)
JFDLEHCO_02005 1.5e-28 ypeQ S Zinc-finger
JFDLEHCO_02006 6.3e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
JFDLEHCO_02007 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JFDLEHCO_02008 4.9e-69 rnhA 3.1.26.4 L Ribonuclease
JFDLEHCO_02010 4.8e-165 polA 2.7.7.7 L 5'3' exonuclease
JFDLEHCO_02012 3.5e-39 ypbS S Protein of unknown function (DUF2533)
JFDLEHCO_02013 0.0 ypbR S Dynamin family
JFDLEHCO_02014 1.1e-89 ypbQ S protein conserved in bacteria
JFDLEHCO_02015 2.8e-207 bcsA Q Naringenin-chalcone synthase
JFDLEHCO_02016 1e-110 J Acetyltransferase (GNAT) domain
JFDLEHCO_02017 6.2e-51 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
JFDLEHCO_02018 1.5e-08 S Bacillus cereus group antimicrobial protein
JFDLEHCO_02019 5.2e-99 ydfR S Protein of unknown function (DUF421)
JFDLEHCO_02020 4.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
JFDLEHCO_02022 1.3e-235 pbuX F xanthine
JFDLEHCO_02023 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JFDLEHCO_02024 3.8e-295 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JFDLEHCO_02025 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
JFDLEHCO_02027 6.6e-22 S YpzG-like protein
JFDLEHCO_02028 3.8e-78 yqgA
JFDLEHCO_02029 4.2e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JFDLEHCO_02030 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JFDLEHCO_02031 1.7e-99 ypsA S Belongs to the UPF0398 family
JFDLEHCO_02032 9.9e-33 cotD S Inner spore coat protein D
JFDLEHCO_02034 7.8e-238 yprB L RNase_H superfamily
JFDLEHCO_02035 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
JFDLEHCO_02036 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
JFDLEHCO_02037 7.7e-73 hspX O Belongs to the small heat shock protein (HSP20) family
JFDLEHCO_02038 1e-51 yppG S YppG-like protein
JFDLEHCO_02040 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
JFDLEHCO_02043 2.6e-188 yppC S Protein of unknown function (DUF2515)
JFDLEHCO_02044 2.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JFDLEHCO_02045 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JFDLEHCO_02046 6.7e-92 ypoC
JFDLEHCO_02047 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JFDLEHCO_02048 3e-130 dnaD L DNA replication protein DnaD
JFDLEHCO_02049 2e-252 asnS 6.1.1.22 J asparaginyl-tRNA
JFDLEHCO_02050 5.2e-223 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JFDLEHCO_02051 3.6e-82 ypmB S protein conserved in bacteria
JFDLEHCO_02052 6.7e-23 ypmA S Protein of unknown function (DUF4264)
JFDLEHCO_02053 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JFDLEHCO_02054 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JFDLEHCO_02055 5e-159 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JFDLEHCO_02056 2.2e-151 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
JFDLEHCO_02057 4.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JFDLEHCO_02058 1.4e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JFDLEHCO_02059 4.3e-211 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
JFDLEHCO_02060 6.7e-133 bshB1 S proteins, LmbE homologs
JFDLEHCO_02061 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
JFDLEHCO_02062 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JFDLEHCO_02063 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
JFDLEHCO_02064 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
JFDLEHCO_02065 3.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
JFDLEHCO_02066 5.1e-142 ypjB S sporulation protein
JFDLEHCO_02067 2.6e-106 ypjA S membrane
JFDLEHCO_02068 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
JFDLEHCO_02069 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
JFDLEHCO_02070 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
JFDLEHCO_02071 2.9e-78 ypiF S Protein of unknown function (DUF2487)
JFDLEHCO_02072 2.1e-99 ypiB S Belongs to the UPF0302 family
JFDLEHCO_02073 1.4e-234 S COG0457 FOG TPR repeat
JFDLEHCO_02074 6.2e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JFDLEHCO_02075 1.8e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
JFDLEHCO_02076 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JFDLEHCO_02077 6.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JFDLEHCO_02078 6.8e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JFDLEHCO_02079 2.4e-121 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
JFDLEHCO_02080 2e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
JFDLEHCO_02081 2.8e-161 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JFDLEHCO_02082 2.3e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JFDLEHCO_02083 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
JFDLEHCO_02084 1e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JFDLEHCO_02085 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JFDLEHCO_02086 4.5e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
JFDLEHCO_02087 5.4e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
JFDLEHCO_02088 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JFDLEHCO_02089 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
JFDLEHCO_02090 1.6e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
JFDLEHCO_02091 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
JFDLEHCO_02092 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
JFDLEHCO_02093 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JFDLEHCO_02094 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JFDLEHCO_02095 5.6e-135 yphF
JFDLEHCO_02096 3.3e-16 yphE S Protein of unknown function (DUF2768)
JFDLEHCO_02097 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JFDLEHCO_02098 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JFDLEHCO_02099 1.1e-104 yphA
JFDLEHCO_02100 4.7e-08 S YpzI-like protein
JFDLEHCO_02101 8.2e-188 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JFDLEHCO_02102 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
JFDLEHCO_02103 3.3e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JFDLEHCO_02104 1.4e-12 S Family of unknown function (DUF5359)
JFDLEHCO_02105 4.8e-19 ypfA M Flagellar protein YcgR
JFDLEHCO_02106 2.2e-26 ypfA M Flagellar protein YcgR
JFDLEHCO_02107 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
JFDLEHCO_02108 4.9e-162 sleB 3.5.1.28 M Spore cortex-lytic enzyme
JFDLEHCO_02109 8.3e-122 prsW S Involved in the degradation of specific anti-sigma factors
JFDLEHCO_02110 9e-189 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
JFDLEHCO_02111 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
JFDLEHCO_02112 3e-107 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
JFDLEHCO_02113 7.3e-149 ypbG S Calcineurin-like phosphoesterase superfamily domain
JFDLEHCO_02114 2e-85 ypbF S Protein of unknown function (DUF2663)
JFDLEHCO_02115 9.4e-85 ypbE M Lysin motif
JFDLEHCO_02116 9.9e-100 ypbD S metal-dependent membrane protease
JFDLEHCO_02117 1.3e-273 recQ 3.6.4.12 L DNA helicase
JFDLEHCO_02118 2.5e-200 ypbB 5.1.3.1 S protein conserved in bacteria
JFDLEHCO_02119 3.6e-41 fer C Ferredoxin
JFDLEHCO_02120 1.1e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JFDLEHCO_02121 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JFDLEHCO_02122 8.8e-201 rsiX
JFDLEHCO_02123 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
JFDLEHCO_02124 0.0 resE 2.7.13.3 T Histidine kinase
JFDLEHCO_02125 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JFDLEHCO_02126 3.2e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
JFDLEHCO_02127 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
JFDLEHCO_02128 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
JFDLEHCO_02129 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JFDLEHCO_02130 1.3e-88 spmB S Spore maturation protein
JFDLEHCO_02131 2e-103 spmA S Spore maturation protein
JFDLEHCO_02132 2.3e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
JFDLEHCO_02133 1.3e-93 ypuI S Protein of unknown function (DUF3907)
JFDLEHCO_02134 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JFDLEHCO_02135 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JFDLEHCO_02137 1.7e-93 ypuF S Domain of unknown function (DUF309)
JFDLEHCO_02138 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JFDLEHCO_02139 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
JFDLEHCO_02140 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JFDLEHCO_02141 2e-112 ribE 2.5.1.9 H Riboflavin synthase
JFDLEHCO_02142 8.6e-212 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JFDLEHCO_02143 1.7e-49 ypuD
JFDLEHCO_02144 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JFDLEHCO_02145 1.3e-82 ccdC1 O Protein of unknown function (DUF1453)
JFDLEHCO_02146 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JFDLEHCO_02147 2.9e-157 ypuA S Secreted protein
JFDLEHCO_02148 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JFDLEHCO_02149 1.4e-270 spoVAF EG Stage V sporulation protein AF
JFDLEHCO_02150 1.8e-110 spoVAEA S stage V sporulation protein
JFDLEHCO_02151 3.8e-57 spoVAEB S stage V sporulation protein
JFDLEHCO_02152 2.9e-190 spoVAD I Stage V sporulation protein AD
JFDLEHCO_02153 2.1e-79 spoVAC S stage V sporulation protein AC
JFDLEHCO_02154 3e-60 spoVAB S Stage V sporulation protein AB
JFDLEHCO_02155 3.7e-111 spoVAA S Stage V sporulation protein AA
JFDLEHCO_02156 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JFDLEHCO_02157 1e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
JFDLEHCO_02158 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
JFDLEHCO_02159 4.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
JFDLEHCO_02160 4.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JFDLEHCO_02161 4.7e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JFDLEHCO_02162 1.7e-165 xerD L recombinase XerD
JFDLEHCO_02163 3.7e-37 S Protein of unknown function (DUF4227)
JFDLEHCO_02164 1.9e-80 fur P Belongs to the Fur family
JFDLEHCO_02165 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
JFDLEHCO_02167 1.7e-34 yqkK
JFDLEHCO_02168 5.7e-22
JFDLEHCO_02169 7.7e-244 mleA 1.1.1.38 C malic enzyme
JFDLEHCO_02170 5.7e-245 mleN C Na H antiporter
JFDLEHCO_02171 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
JFDLEHCO_02172 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
JFDLEHCO_02173 7e-59 ansR K Transcriptional regulator
JFDLEHCO_02174 1.6e-224 yqxK 3.6.4.12 L DNA helicase
JFDLEHCO_02175 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
JFDLEHCO_02177 3.3e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
JFDLEHCO_02179 3.9e-178 yqkD S COG1073 Hydrolases of the alpha beta superfamily
JFDLEHCO_02180 3.2e-39 yqkC S Protein of unknown function (DUF2552)
JFDLEHCO_02181 2e-61 yqkB S Belongs to the HesB IscA family
JFDLEHCO_02182 2.5e-180 yqkA K GrpB protein
JFDLEHCO_02183 4.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
JFDLEHCO_02184 3.9e-89 yqjY K acetyltransferase
JFDLEHCO_02185 1.3e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JFDLEHCO_02186 5.3e-59 S YolD-like protein
JFDLEHCO_02188 2.8e-191 yueF S transporter activity
JFDLEHCO_02190 6.6e-74 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JFDLEHCO_02191 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
JFDLEHCO_02192 2.1e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
JFDLEHCO_02193 4.1e-144 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
JFDLEHCO_02194 4.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
JFDLEHCO_02195 2.1e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JFDLEHCO_02196 1.8e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
JFDLEHCO_02197 4.4e-241 pksG 2.3.3.10 I synthase
JFDLEHCO_02198 1.2e-221 eryK 1.14.13.154 C Cytochrome P450
JFDLEHCO_02199 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
JFDLEHCO_02200 0.0 Q Polyketide synthase of type I
JFDLEHCO_02201 0.0 pfaA Q Polyketide synthase of type I
JFDLEHCO_02202 0.0 pksJ Q Polyketide synthase of type I
JFDLEHCO_02203 0.0 Q Polyketide synthase of type I
JFDLEHCO_02204 0.0 1.1.1.320 Q Polyketide synthase of type I
JFDLEHCO_02205 0.0 pksJ Q Polyketide synthase of type I
JFDLEHCO_02206 1.9e-130 IQ reductase
JFDLEHCO_02207 3.4e-250 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JFDLEHCO_02210 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JFDLEHCO_02211 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
JFDLEHCO_02212 2.4e-164 K LysR substrate binding domain
JFDLEHCO_02213 3.8e-51 S GlpM protein
JFDLEHCO_02214 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
JFDLEHCO_02215 1e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JFDLEHCO_02216 6.5e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JFDLEHCO_02217 2.5e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JFDLEHCO_02218 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JFDLEHCO_02219 3.9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JFDLEHCO_02220 2.4e-25 yqzJ
JFDLEHCO_02221 1.2e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JFDLEHCO_02222 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
JFDLEHCO_02223 3.6e-293 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
JFDLEHCO_02224 1.3e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
JFDLEHCO_02226 1.7e-96 yqjB S protein conserved in bacteria
JFDLEHCO_02227 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
JFDLEHCO_02228 2.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JFDLEHCO_02229 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
JFDLEHCO_02230 3.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
JFDLEHCO_02231 1e-75 yqiW S Belongs to the UPF0403 family
JFDLEHCO_02232 4.1e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JFDLEHCO_02233 1.3e-208 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JFDLEHCO_02234 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JFDLEHCO_02235 2.3e-168 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JFDLEHCO_02236 6.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JFDLEHCO_02237 2e-208 buk 2.7.2.7 C Belongs to the acetokinase family
JFDLEHCO_02238 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
JFDLEHCO_02239 1.1e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
JFDLEHCO_02240 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
JFDLEHCO_02241 3.2e-34 yqzF S Protein of unknown function (DUF2627)
JFDLEHCO_02242 3.3e-161 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JFDLEHCO_02243 5.5e-280 prpD 4.2.1.79 S 2-methylcitrate dehydratase
JFDLEHCO_02244 1.1e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
JFDLEHCO_02245 3.4e-208 mmgC I acyl-CoA dehydrogenase
JFDLEHCO_02246 3e-156 hbdA 1.1.1.157 I Dehydrogenase
JFDLEHCO_02247 3.4e-214 mmgA 2.3.1.9 I Belongs to the thiolase family
JFDLEHCO_02248 5.1e-136 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JFDLEHCO_02249 3.6e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
JFDLEHCO_02250 3.2e-17
JFDLEHCO_02251 1.5e-101 ytaF P Probably functions as a manganese efflux pump
JFDLEHCO_02252 1.8e-113 K Protein of unknown function (DUF1232)
JFDLEHCO_02254 1.4e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
JFDLEHCO_02257 2.7e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JFDLEHCO_02258 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
JFDLEHCO_02259 2.3e-240 rseP 3.4.21.116 M Stage IV sporulation protein B
JFDLEHCO_02260 0.0 recN L May be involved in recombinational repair of damaged DNA
JFDLEHCO_02261 3.9e-78 argR K Regulates arginine biosynthesis genes
JFDLEHCO_02262 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
JFDLEHCO_02263 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JFDLEHCO_02264 9.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JFDLEHCO_02265 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JFDLEHCO_02266 3.2e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JFDLEHCO_02267 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JFDLEHCO_02268 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JFDLEHCO_02269 6.2e-67 yqhY S protein conserved in bacteria
JFDLEHCO_02270 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
JFDLEHCO_02271 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JFDLEHCO_02272 2.5e-62 spoIIIAH S SpoIIIAH-like protein
JFDLEHCO_02273 3.4e-118 spoIIIAG S stage III sporulation protein AG
JFDLEHCO_02274 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
JFDLEHCO_02275 6.3e-200 spoIIIAE S stage III sporulation protein AE
JFDLEHCO_02276 2.5e-41 spoIIIAD S Stage III sporulation protein AD
JFDLEHCO_02277 7.6e-29 spoIIIAC S stage III sporulation protein AC
JFDLEHCO_02278 5.8e-86 spoIIIAB S Stage III sporulation protein
JFDLEHCO_02279 1.1e-172 spoIIIAA S stage III sporulation protein AA
JFDLEHCO_02280 1.8e-36 yqhV S Protein of unknown function (DUF2619)
JFDLEHCO_02281 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JFDLEHCO_02282 5e-177 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
JFDLEHCO_02283 3.7e-88 yqhR S Conserved membrane protein YqhR
JFDLEHCO_02284 8e-174 yqhQ S Protein of unknown function (DUF1385)
JFDLEHCO_02285 3.4e-62 yqhP
JFDLEHCO_02286 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
JFDLEHCO_02287 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
JFDLEHCO_02288 4e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
JFDLEHCO_02289 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
JFDLEHCO_02290 1.5e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JFDLEHCO_02291 3.8e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JFDLEHCO_02292 3.6e-210 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
JFDLEHCO_02293 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
JFDLEHCO_02294 2.6e-154 yqhG S Bacterial protein YqhG of unknown function
JFDLEHCO_02295 5.2e-23 sinI S Anti-repressor SinI
JFDLEHCO_02296 7.8e-55 sinR K transcriptional
JFDLEHCO_02297 3.3e-141 tasA S Cell division protein FtsN
JFDLEHCO_02298 3.5e-71 sipW 3.4.21.89 U Signal peptidase
JFDLEHCO_02299 3.5e-123 yqxM
JFDLEHCO_02300 1.3e-54 yqzG S Protein of unknown function (DUF3889)
JFDLEHCO_02301 2.3e-26 yqzE S YqzE-like protein
JFDLEHCO_02302 7.8e-64 S ComG operon protein 7
JFDLEHCO_02303 1.5e-68 comGF U Putative Competence protein ComGF
JFDLEHCO_02304 5.8e-20 comGE
JFDLEHCO_02305 1.6e-73 gspH NU Tfp pilus assembly protein FimT
JFDLEHCO_02306 8.9e-50 comGC U Required for transformation and DNA binding
JFDLEHCO_02307 1.8e-187 comGB NU COG1459 Type II secretory pathway, component PulF
JFDLEHCO_02308 7.8e-202 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JFDLEHCO_02309 4.1e-186 corA P Mg2 transporter protein
JFDLEHCO_02310 3.3e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JFDLEHCO_02311 2.4e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JFDLEHCO_02313 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
JFDLEHCO_02314 3.1e-37 yqgY S Protein of unknown function (DUF2626)
JFDLEHCO_02315 1.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
JFDLEHCO_02316 5.4e-20 yqgW S Protein of unknown function (DUF2759)
JFDLEHCO_02317 6.9e-50 yqgV S Thiamine-binding protein
JFDLEHCO_02318 2.4e-200 yqgU
JFDLEHCO_02319 2.6e-224 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
JFDLEHCO_02320 2.6e-180 glcK 2.7.1.2 G Glucokinase
JFDLEHCO_02321 2.9e-233 nhaC C Na H antiporter
JFDLEHCO_02322 4e-07 yqgO
JFDLEHCO_02323 3.4e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JFDLEHCO_02324 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JFDLEHCO_02325 1.2e-50 yqzD
JFDLEHCO_02326 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JFDLEHCO_02327 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JFDLEHCO_02328 1.8e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JFDLEHCO_02329 6.3e-157 pstA P Phosphate transport system permease
JFDLEHCO_02330 1.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
JFDLEHCO_02331 7.6e-158 pstS P Phosphate
JFDLEHCO_02332 2.2e-54 L COG2963 Transposase and inactivated derivatives
JFDLEHCO_02333 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
JFDLEHCO_02334 0.0 pbpA 3.4.16.4 M penicillin-binding protein
JFDLEHCO_02335 2e-228 yqgE EGP Major facilitator superfamily
JFDLEHCO_02336 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
JFDLEHCO_02337 6e-77 yqgC S protein conserved in bacteria
JFDLEHCO_02338 8.7e-131 yqgB S Protein of unknown function (DUF1189)
JFDLEHCO_02339 3.7e-48 yqfZ M LysM domain
JFDLEHCO_02340 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JFDLEHCO_02341 2.3e-52 yqfX S membrane
JFDLEHCO_02342 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
JFDLEHCO_02343 2.9e-72 zur P Belongs to the Fur family
JFDLEHCO_02344 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
JFDLEHCO_02345 9.3e-37 yqfT S Protein of unknown function (DUF2624)
JFDLEHCO_02346 2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JFDLEHCO_02347 6.7e-248 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JFDLEHCO_02348 6.2e-51 yqfQ S YqfQ-like protein
JFDLEHCO_02349 1.7e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JFDLEHCO_02350 1.7e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JFDLEHCO_02351 5.8e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
JFDLEHCO_02352 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
JFDLEHCO_02353 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JFDLEHCO_02354 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JFDLEHCO_02355 2.1e-88 yaiI S Belongs to the UPF0178 family
JFDLEHCO_02356 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
JFDLEHCO_02357 4.5e-112 ccpN K CBS domain
JFDLEHCO_02358 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JFDLEHCO_02359 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JFDLEHCO_02360 4.1e-144 recO L Involved in DNA repair and RecF pathway recombination
JFDLEHCO_02361 1.8e-16 S YqzL-like protein
JFDLEHCO_02362 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JFDLEHCO_02363 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JFDLEHCO_02364 4.6e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JFDLEHCO_02365 2.5e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JFDLEHCO_02366 0.0 yqfF S membrane-associated HD superfamily hydrolase
JFDLEHCO_02367 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
JFDLEHCO_02368 1.9e-217 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
JFDLEHCO_02369 9.3e-46 yqfC S sporulation protein YqfC
JFDLEHCO_02370 2.8e-57 yqfB
JFDLEHCO_02371 1.6e-121 yqfA S UPF0365 protein
JFDLEHCO_02372 2e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
JFDLEHCO_02373 1.2e-68 yqeY S Yqey-like protein
JFDLEHCO_02374 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JFDLEHCO_02375 9.3e-159 yqeW P COG1283 Na phosphate symporter
JFDLEHCO_02376 1.2e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
JFDLEHCO_02377 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JFDLEHCO_02378 1.6e-174 prmA J Methylates ribosomal protein L11
JFDLEHCO_02379 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JFDLEHCO_02380 0.0 dnaK O Heat shock 70 kDa protein
JFDLEHCO_02381 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JFDLEHCO_02382 2.3e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JFDLEHCO_02383 2.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
JFDLEHCO_02384 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JFDLEHCO_02385 3.8e-54 yqxA S Protein of unknown function (DUF3679)
JFDLEHCO_02386 1.4e-220 spoIIP M stage II sporulation protein P
JFDLEHCO_02387 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JFDLEHCO_02388 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
JFDLEHCO_02389 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
JFDLEHCO_02390 0.0 comEC S Competence protein ComEC
JFDLEHCO_02391 8e-105 comEB 3.5.4.12 F ComE operon protein 2
JFDLEHCO_02392 7.8e-106 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
JFDLEHCO_02393 2.2e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JFDLEHCO_02394 5.8e-140 yqeM Q Methyltransferase
JFDLEHCO_02395 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JFDLEHCO_02396 2.5e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
JFDLEHCO_02397 5.9e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JFDLEHCO_02398 1.6e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
JFDLEHCO_02399 4.9e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JFDLEHCO_02400 2.4e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
JFDLEHCO_02401 2e-94 yqeG S hydrolase of the HAD superfamily
JFDLEHCO_02403 9.1e-141 yqeF E GDSL-like Lipase/Acylhydrolase
JFDLEHCO_02404 2.1e-142 3.5.1.104 G Polysaccharide deacetylase
JFDLEHCO_02405 4.2e-107 yqeD S SNARE associated Golgi protein
JFDLEHCO_02406 3.9e-16 2.3.1.57 K Acetyltransferase (GNAT) domain
JFDLEHCO_02407 3.6e-222 EGP Major facilitator Superfamily
JFDLEHCO_02408 4e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JFDLEHCO_02409 1.9e-163 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
JFDLEHCO_02410 3.8e-93 K Transcriptional regulator PadR-like family
JFDLEHCO_02411 3e-69 psiE S Belongs to the PsiE family
JFDLEHCO_02412 4.3e-239 yrkQ T Histidine kinase
JFDLEHCO_02413 1.1e-127 T Transcriptional regulator
JFDLEHCO_02415 1.1e-223 yrkO P Protein of unknown function (DUF418)
JFDLEHCO_02416 3.8e-104 yrkN K Acetyltransferase (GNAT) family
JFDLEHCO_02417 2.9e-101 adk 2.7.4.3 F adenylate kinase activity
JFDLEHCO_02418 4.9e-87 yyaR K acetyltransferase
JFDLEHCO_02419 4.7e-93 yrdA S DinB family
JFDLEHCO_02421 4.4e-149 S hydrolase
JFDLEHCO_02422 5.2e-150 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
JFDLEHCO_02423 2.4e-130 glvR K Helix-turn-helix domain, rpiR family
JFDLEHCO_02424 8.4e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
JFDLEHCO_02425 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
JFDLEHCO_02426 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
JFDLEHCO_02427 2.1e-184 romA S Beta-lactamase superfamily domain
JFDLEHCO_02428 1.2e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JFDLEHCO_02429 9.7e-166 yybE K Transcriptional regulator
JFDLEHCO_02430 4.8e-216 ynfM EGP Major facilitator Superfamily
JFDLEHCO_02431 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
JFDLEHCO_02432 9.1e-101 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
JFDLEHCO_02433 1.2e-94 yrhH Q methyltransferase
JFDLEHCO_02435 8e-143 focA P Formate nitrite
JFDLEHCO_02436 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
JFDLEHCO_02437 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
JFDLEHCO_02438 7e-81 yrhD S Protein of unknown function (DUF1641)
JFDLEHCO_02439 4.6e-35 yrhC S YrhC-like protein
JFDLEHCO_02440 1.4e-212 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JFDLEHCO_02441 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
JFDLEHCO_02442 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JFDLEHCO_02443 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
JFDLEHCO_02444 4.1e-27 yrzA S Protein of unknown function (DUF2536)
JFDLEHCO_02445 9.5e-71 yrrS S Protein of unknown function (DUF1510)
JFDLEHCO_02446 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
JFDLEHCO_02447 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JFDLEHCO_02448 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
JFDLEHCO_02449 1.6e-246 yegQ O COG0826 Collagenase and related proteases
JFDLEHCO_02450 2e-174 yegQ O Peptidase U32
JFDLEHCO_02451 2.5e-118 yrrM 2.1.1.104 S O-methyltransferase
JFDLEHCO_02452 5.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JFDLEHCO_02453 7.1e-46 yrzB S Belongs to the UPF0473 family
JFDLEHCO_02454 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JFDLEHCO_02455 1.7e-41 yrzL S Belongs to the UPF0297 family
JFDLEHCO_02456 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JFDLEHCO_02457 5.2e-166 yrrI S AI-2E family transporter
JFDLEHCO_02458 7.5e-132 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JFDLEHCO_02459 1.5e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
JFDLEHCO_02460 4.2e-110 gluC P ABC transporter
JFDLEHCO_02461 3.1e-108 glnP P ABC transporter
JFDLEHCO_02462 2.1e-08 S Protein of unknown function (DUF3918)
JFDLEHCO_02463 2.9e-30 yrzR
JFDLEHCO_02464 1.8e-83 yrrD S protein conserved in bacteria
JFDLEHCO_02465 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JFDLEHCO_02466 1.7e-18 S COG0457 FOG TPR repeat
JFDLEHCO_02467 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JFDLEHCO_02468 1e-212 iscS 2.8.1.7 E Cysteine desulfurase
JFDLEHCO_02469 7.8e-64 cymR K Transcriptional regulator
JFDLEHCO_02470 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
JFDLEHCO_02471 2.5e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
JFDLEHCO_02472 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JFDLEHCO_02473 8.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
JFDLEHCO_02476 6.1e-280 lytH 3.5.1.28 M COG3103 SH3 domain protein
JFDLEHCO_02477 1.4e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JFDLEHCO_02478 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JFDLEHCO_02479 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JFDLEHCO_02480 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
JFDLEHCO_02481 5.2e-48 yrvD S Lipopolysaccharide assembly protein A domain
JFDLEHCO_02482 1.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
JFDLEHCO_02483 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JFDLEHCO_02484 1.3e-50 yrzD S Post-transcriptional regulator
JFDLEHCO_02485 7.2e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JFDLEHCO_02486 9.5e-110 yrbG S membrane
JFDLEHCO_02487 2.4e-60 yrzE S Protein of unknown function (DUF3792)
JFDLEHCO_02488 3.3e-37 yajC U Preprotein translocase subunit YajC
JFDLEHCO_02489 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JFDLEHCO_02490 1.7e-193 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JFDLEHCO_02491 6.2e-20 yrzS S Protein of unknown function (DUF2905)
JFDLEHCO_02492 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JFDLEHCO_02493 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JFDLEHCO_02494 3.7e-93 bofC S BofC C-terminal domain
JFDLEHCO_02496 1.4e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JFDLEHCO_02497 3.9e-149 safA M spore coat assembly protein SafA
JFDLEHCO_02498 8.2e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JFDLEHCO_02499 6.7e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
JFDLEHCO_02500 2.3e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
JFDLEHCO_02501 8.3e-226 nifS 2.8.1.7 E Cysteine desulfurase
JFDLEHCO_02502 1.1e-95 niaR S small molecule binding protein (contains 3H domain)
JFDLEHCO_02503 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
JFDLEHCO_02504 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
JFDLEHCO_02505 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JFDLEHCO_02506 8.7e-107 spo0B T Sporulation initiation phospho-transferase B, C-terminal
JFDLEHCO_02507 4.2e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JFDLEHCO_02508 3.2e-56 ysxB J ribosomal protein
JFDLEHCO_02509 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
JFDLEHCO_02510 1.2e-160 spoIVFB S Stage IV sporulation protein
JFDLEHCO_02511 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
JFDLEHCO_02512 8e-143 minD D Belongs to the ParA family
JFDLEHCO_02513 3.9e-98 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
JFDLEHCO_02514 1.4e-84 mreD M shape-determining protein
JFDLEHCO_02515 1.2e-157 mreC M Involved in formation and maintenance of cell shape
JFDLEHCO_02516 4e-184 mreB D Rod shape-determining protein MreB
JFDLEHCO_02517 1.8e-127 radC E Belongs to the UPF0758 family
JFDLEHCO_02518 2.4e-101 maf D septum formation protein Maf
JFDLEHCO_02519 1e-139 spoIIB S Sporulation related domain
JFDLEHCO_02520 3.5e-132 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
JFDLEHCO_02521 6.4e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JFDLEHCO_02522 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JFDLEHCO_02523 2.1e-25
JFDLEHCO_02524 8.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JFDLEHCO_02525 3.5e-242 spoVID M stage VI sporulation protein D
JFDLEHCO_02526 1.2e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
JFDLEHCO_02527 1e-184 hemB 4.2.1.24 H Belongs to the ALAD family
JFDLEHCO_02528 2.7e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JFDLEHCO_02529 2.4e-175 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
JFDLEHCO_02530 3.6e-146 hemX O cytochrome C
JFDLEHCO_02531 1.4e-248 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JFDLEHCO_02532 1.5e-88 ysxD
JFDLEHCO_02533 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
JFDLEHCO_02534 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JFDLEHCO_02535 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
JFDLEHCO_02536 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JFDLEHCO_02537 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JFDLEHCO_02538 2.4e-189 ysoA H Tetratricopeptide repeat
JFDLEHCO_02539 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JFDLEHCO_02540 6.3e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JFDLEHCO_02541 6.7e-201 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
JFDLEHCO_02542 5.3e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JFDLEHCO_02543 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JFDLEHCO_02544 5.4e-84 ilvN 2.2.1.6 E Acetolactate synthase
JFDLEHCO_02545 0.0 ilvB 2.2.1.6 E Acetolactate synthase
JFDLEHCO_02550 4.8e-93 ysnB S Phosphoesterase
JFDLEHCO_02551 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JFDLEHCO_02552 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JFDLEHCO_02553 2.8e-199 gerM S COG5401 Spore germination protein
JFDLEHCO_02554 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JFDLEHCO_02555 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
JFDLEHCO_02556 2e-30 gerE K Transcriptional regulator
JFDLEHCO_02557 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
JFDLEHCO_02558 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
JFDLEHCO_02559 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
JFDLEHCO_02560 4.8e-108 sdhC C succinate dehydrogenase
JFDLEHCO_02561 5.4e-80 yslB S Protein of unknown function (DUF2507)
JFDLEHCO_02562 2.9e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
JFDLEHCO_02563 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JFDLEHCO_02564 2.5e-52 trxA O Belongs to the thioredoxin family
JFDLEHCO_02565 3e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
JFDLEHCO_02566 2.9e-179 etfA C Electron transfer flavoprotein
JFDLEHCO_02567 2e-138 etfB C Electron transfer flavoprotein
JFDLEHCO_02568 1.3e-137 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
JFDLEHCO_02569 9.2e-104 fadR K Transcriptional regulator
JFDLEHCO_02570 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JFDLEHCO_02571 1e-127 ywbB S Protein of unknown function (DUF2711)
JFDLEHCO_02572 4.7e-67 yshE S membrane
JFDLEHCO_02573 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JFDLEHCO_02574 0.0 polX L COG1796 DNA polymerase IV (family X)
JFDLEHCO_02575 1.6e-83 cvpA S membrane protein, required for colicin V production
JFDLEHCO_02576 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JFDLEHCO_02577 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JFDLEHCO_02578 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JFDLEHCO_02579 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JFDLEHCO_02580 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JFDLEHCO_02581 2e-32 sspI S Belongs to the SspI family
JFDLEHCO_02582 2.4e-206 ysfB KT regulator
JFDLEHCO_02583 7.5e-261 glcD 1.1.3.15 C FAD binding domain
JFDLEHCO_02584 8.6e-259 glcF C Glycolate oxidase
JFDLEHCO_02585 0.0 cstA T Carbon starvation protein
JFDLEHCO_02586 1.2e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
JFDLEHCO_02587 1.2e-144 araQ G transport system permease
JFDLEHCO_02588 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
JFDLEHCO_02589 1.8e-253 araN G carbohydrate transport
JFDLEHCO_02590 7.7e-227 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
JFDLEHCO_02591 1.1e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
JFDLEHCO_02592 3.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
JFDLEHCO_02593 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
JFDLEHCO_02594 3.3e-299 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
JFDLEHCO_02595 1.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
JFDLEHCO_02596 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
JFDLEHCO_02597 9.2e-68 ysdB S Sigma-w pathway protein YsdB
JFDLEHCO_02598 8.2e-44 ysdA S Membrane
JFDLEHCO_02599 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JFDLEHCO_02600 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JFDLEHCO_02601 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JFDLEHCO_02602 1.7e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
JFDLEHCO_02603 3.1e-40 lrgA S effector of murein hydrolase LrgA
JFDLEHCO_02604 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
JFDLEHCO_02605 0.0 lytS 2.7.13.3 T Histidine kinase
JFDLEHCO_02606 5.5e-152 ysaA S HAD-hyrolase-like
JFDLEHCO_02607 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JFDLEHCO_02608 2.5e-155 ytxC S YtxC-like family
JFDLEHCO_02609 9.3e-110 ytxB S SNARE associated Golgi protein
JFDLEHCO_02610 4.3e-172 dnaI L Primosomal protein DnaI
JFDLEHCO_02611 4.5e-258 dnaB L Membrane attachment protein
JFDLEHCO_02612 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JFDLEHCO_02613 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JFDLEHCO_02614 1.4e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JFDLEHCO_02615 2e-67 ytcD K Transcriptional regulator
JFDLEHCO_02616 1.2e-206 ytbD EGP Major facilitator Superfamily
JFDLEHCO_02617 5.2e-161 ytbE S reductase
JFDLEHCO_02618 4.7e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JFDLEHCO_02619 9.5e-107 ytaF P Probably functions as a manganese efflux pump
JFDLEHCO_02620 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JFDLEHCO_02621 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JFDLEHCO_02622 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
JFDLEHCO_02623 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JFDLEHCO_02624 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
JFDLEHCO_02625 3.1e-242 icd 1.1.1.42 C isocitrate
JFDLEHCO_02626 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
JFDLEHCO_02627 7.7e-49 yjdF S Protein of unknown function (DUF2992)
JFDLEHCO_02628 1.1e-72 yeaL S membrane
JFDLEHCO_02629 3.6e-194 ytvI S sporulation integral membrane protein YtvI
JFDLEHCO_02630 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
JFDLEHCO_02631 6.8e-296 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JFDLEHCO_02632 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JFDLEHCO_02633 6.2e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
JFDLEHCO_02634 6.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JFDLEHCO_02635 2.6e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
JFDLEHCO_02636 0.0 dnaE 2.7.7.7 L DNA polymerase
JFDLEHCO_02637 3.2e-56 ytrH S Sporulation protein YtrH
JFDLEHCO_02638 5.1e-87 ytrI
JFDLEHCO_02639 4.4e-23
JFDLEHCO_02640 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
JFDLEHCO_02641 8.2e-48 ytpI S YtpI-like protein
JFDLEHCO_02642 7.5e-239 ytoI K transcriptional regulator containing CBS domains
JFDLEHCO_02643 1.1e-129 ytkL S Belongs to the UPF0173 family
JFDLEHCO_02644 4.5e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JFDLEHCO_02646 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
JFDLEHCO_02647 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JFDLEHCO_02648 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
JFDLEHCO_02649 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JFDLEHCO_02650 3.6e-185 ytxK 2.1.1.72 L DNA methylase
JFDLEHCO_02651 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JFDLEHCO_02652 1.6e-60 ytfJ S Sporulation protein YtfJ
JFDLEHCO_02653 1.1e-119 ytfI S Protein of unknown function (DUF2953)
JFDLEHCO_02654 4.5e-88 yteJ S RDD family
JFDLEHCO_02655 2.9e-182 sppA OU signal peptide peptidase SppA
JFDLEHCO_02656 1.5e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JFDLEHCO_02657 0.0 ytcJ S amidohydrolase
JFDLEHCO_02658 1.6e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
JFDLEHCO_02659 3.9e-31 sspB S spore protein
JFDLEHCO_02660 3.9e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JFDLEHCO_02661 1.7e-210 iscS2 2.8.1.7 E Cysteine desulfurase
JFDLEHCO_02662 1.8e-240 braB E Component of the transport system for branched-chain amino acids
JFDLEHCO_02663 1e-264 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JFDLEHCO_02664 1.9e-155 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
JFDLEHCO_02665 4.1e-110 yttP K Transcriptional regulator
JFDLEHCO_02666 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
JFDLEHCO_02667 9.2e-285 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
JFDLEHCO_02668 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JFDLEHCO_02669 1.7e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
JFDLEHCO_02670 2.7e-105 yokH G SMI1 / KNR4 family
JFDLEHCO_02672 1.3e-102
JFDLEHCO_02674 1.2e-88 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
JFDLEHCO_02676 1.4e-28 S Phage-like element PBSX protein XtrA
JFDLEHCO_02677 5.2e-30
JFDLEHCO_02678 1.8e-33 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JFDLEHCO_02679 2.3e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JFDLEHCO_02680 7.3e-09
JFDLEHCO_02681 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
JFDLEHCO_02683 2.4e-141 E GDSL-like Lipase/Acylhydrolase family
JFDLEHCO_02684 5.1e-151 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JFDLEHCO_02685 4.4e-149 K Transcriptional regulator
JFDLEHCO_02686 5.2e-125 azlC E AzlC protein
JFDLEHCO_02687 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
JFDLEHCO_02688 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JFDLEHCO_02689 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
JFDLEHCO_02690 2.8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
JFDLEHCO_02691 2.5e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
JFDLEHCO_02692 2.3e-231 acuC BQ histone deacetylase
JFDLEHCO_02693 7.4e-121 motS N Flagellar motor protein
JFDLEHCO_02694 3e-145 motA N flagellar motor
JFDLEHCO_02695 2.9e-182 ccpA K catabolite control protein A
JFDLEHCO_02696 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
JFDLEHCO_02697 1.7e-43 ytxJ O Protein of unknown function (DUF2847)
JFDLEHCO_02698 1.7e-16 ytxH S COG4980 Gas vesicle protein
JFDLEHCO_02699 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JFDLEHCO_02700 9.9e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JFDLEHCO_02701 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
JFDLEHCO_02702 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JFDLEHCO_02703 3.7e-148 ytpQ S Belongs to the UPF0354 family
JFDLEHCO_02704 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JFDLEHCO_02705 2.7e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
JFDLEHCO_02706 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
JFDLEHCO_02707 1.7e-51 ytzB S small secreted protein
JFDLEHCO_02708 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
JFDLEHCO_02709 7.1e-166 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
JFDLEHCO_02710 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JFDLEHCO_02711 9.2e-46 ytzH S YtzH-like protein
JFDLEHCO_02712 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
JFDLEHCO_02713 7.7e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
JFDLEHCO_02714 9.5e-172 ytlQ
JFDLEHCO_02715 2.8e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JFDLEHCO_02716 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JFDLEHCO_02717 1.4e-272 pepV 3.5.1.18 E Dipeptidase
JFDLEHCO_02718 4.1e-229 pbuO S permease
JFDLEHCO_02719 1.5e-219 ythQ U Bacterial ABC transporter protein EcsB
JFDLEHCO_02720 3.4e-129 ythP V ABC transporter
JFDLEHCO_02721 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
JFDLEHCO_02722 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JFDLEHCO_02723 2e-294 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JFDLEHCO_02724 1.5e-236 ytfP S HI0933-like protein
JFDLEHCO_02725 4.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
JFDLEHCO_02726 9e-26 yteV S Sporulation protein Cse60
JFDLEHCO_02727 3e-187 msmR K Transcriptional regulator
JFDLEHCO_02728 1.1e-247 msmE G Bacterial extracellular solute-binding protein
JFDLEHCO_02729 3.3e-169 amyD G Binding-protein-dependent transport system inner membrane component
JFDLEHCO_02730 4.8e-143 amyC P ABC transporter (permease)
JFDLEHCO_02731 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
JFDLEHCO_02732 2.4e-86 M Acetyltransferase (GNAT) domain
JFDLEHCO_02733 5.6e-52 ytwF P Sulfurtransferase
JFDLEHCO_02734 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JFDLEHCO_02735 1.2e-52 ytvB S Protein of unknown function (DUF4257)
JFDLEHCO_02736 6.6e-140 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
JFDLEHCO_02737 5.6e-209 yttB EGP Major facilitator Superfamily
JFDLEHCO_02738 1.7e-131 ywaF S Integral membrane protein
JFDLEHCO_02739 0.0 bceB V ABC transporter (permease)
JFDLEHCO_02740 5.8e-135 bceA V ABC transporter, ATP-binding protein
JFDLEHCO_02741 1.3e-171 T PhoQ Sensor
JFDLEHCO_02742 2e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JFDLEHCO_02743 3.7e-222 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
JFDLEHCO_02744 1.3e-125 ytrE V ABC transporter, ATP-binding protein
JFDLEHCO_02745 2.5e-162
JFDLEHCO_02746 8.8e-176 P ABC-2 family transporter protein
JFDLEHCO_02747 1e-176 S ABC-2 family transporter protein
JFDLEHCO_02748 3.8e-162 ytrB P abc transporter atp-binding protein
JFDLEHCO_02749 3.9e-66 ytrA K GntR family transcriptional regulator
JFDLEHCO_02751 7.4e-40 ytzC S Protein of unknown function (DUF2524)
JFDLEHCO_02752 0.0 IQ AMP-binding enzyme
JFDLEHCO_02753 1e-204 K helix_turn_helix, Arsenical Resistance Operon Repressor
JFDLEHCO_02754 0.0 Q Polyketide synthase of type I
JFDLEHCO_02755 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_02756 3.1e-189 C Nitroreductase
JFDLEHCO_02757 8.6e-133 nrsA Q Thioesterase domain
JFDLEHCO_02758 2.2e-288 norB EGP COG0477 Permeases of the major facilitator superfamily
JFDLEHCO_02759 2.1e-190 yhcC S Fe-S oxidoreductase
JFDLEHCO_02760 3.9e-107 ytqB J Putative rRNA methylase
JFDLEHCO_02762 8.6e-145 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
JFDLEHCO_02763 4.4e-213 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
JFDLEHCO_02764 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
JFDLEHCO_02765 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JFDLEHCO_02766 1.9e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
JFDLEHCO_02767 0.0 asnB 6.3.5.4 E Asparagine synthase
JFDLEHCO_02768 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JFDLEHCO_02769 1.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JFDLEHCO_02770 1.6e-38 ytmB S Protein of unknown function (DUF2584)
JFDLEHCO_02771 3.2e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
JFDLEHCO_02772 6.6e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
JFDLEHCO_02773 2.9e-145 ytlC P ABC transporter
JFDLEHCO_02774 5.8e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
JFDLEHCO_02775 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
JFDLEHCO_02776 6e-62 ytkC S Bacteriophage holin family
JFDLEHCO_02777 3.2e-77 dps P Belongs to the Dps family
JFDLEHCO_02779 7.2e-77 ytkA S YtkA-like
JFDLEHCO_02780 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JFDLEHCO_02781 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
JFDLEHCO_02782 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
JFDLEHCO_02783 1.6e-41 rpmE2 J Ribosomal protein L31
JFDLEHCO_02784 6.8e-240 cydA 1.10.3.14 C oxidase, subunit
JFDLEHCO_02785 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
JFDLEHCO_02786 2.3e-24 S Domain of Unknown Function (DUF1540)
JFDLEHCO_02787 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
JFDLEHCO_02788 3.3e-280 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
JFDLEHCO_02789 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JFDLEHCO_02790 1.7e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
JFDLEHCO_02791 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JFDLEHCO_02792 3.1e-275 menF 5.4.4.2 HQ Isochorismate synthase
JFDLEHCO_02793 2e-132 dksA T COG1734 DnaK suppressor protein
JFDLEHCO_02794 6.2e-79 tspO T membrane
JFDLEHCO_02803 7.8e-08
JFDLEHCO_02804 1.3e-09
JFDLEHCO_02811 1.6e-08
JFDLEHCO_02816 3.4e-39 S COG NOG14552 non supervised orthologous group
JFDLEHCO_02817 3.3e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
JFDLEHCO_02818 7e-180 yuaG 3.4.21.72 S protein conserved in bacteria
JFDLEHCO_02819 1.3e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
JFDLEHCO_02820 5.1e-84 yuaE S DinB superfamily
JFDLEHCO_02821 6.5e-110 yuaD S MOSC domain
JFDLEHCO_02822 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
JFDLEHCO_02823 1.2e-285 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
JFDLEHCO_02824 2.7e-97 yuaC K Belongs to the GbsR family
JFDLEHCO_02825 2.1e-94 yuaB
JFDLEHCO_02826 1.1e-121 ktrA P COG0569 K transport systems, NAD-binding component
JFDLEHCO_02827 6.7e-148 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JFDLEHCO_02828 2.4e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JFDLEHCO_02829 1.3e-124 G Cupin
JFDLEHCO_02830 6.2e-54 yjcN
JFDLEHCO_02832 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JFDLEHCO_02833 9e-196 yubA S transporter activity
JFDLEHCO_02834 1.9e-186 ygjR S Oxidoreductase
JFDLEHCO_02835 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
JFDLEHCO_02836 1e-239 mcpA NT chemotaxis protein
JFDLEHCO_02837 1.1e-225 mcpA NT chemotaxis protein
JFDLEHCO_02838 1.9e-241 mcpA NT chemotaxis protein
JFDLEHCO_02839 1.7e-223 mcpA NT chemotaxis protein
JFDLEHCO_02840 9e-141 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
JFDLEHCO_02841 4.8e-41
JFDLEHCO_02842 1.8e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
JFDLEHCO_02843 2.8e-78 yugU S Uncharacterised protein family UPF0047
JFDLEHCO_02844 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
JFDLEHCO_02845 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
JFDLEHCO_02846 8.3e-117 yugP S Zn-dependent protease
JFDLEHCO_02847 4.5e-18
JFDLEHCO_02848 1.1e-26 mstX S Membrane-integrating protein Mistic
JFDLEHCO_02849 6.3e-182 yugO P COG1226 Kef-type K transport systems
JFDLEHCO_02850 1.3e-72 yugN S YugN-like family
JFDLEHCO_02852 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
JFDLEHCO_02853 2.1e-97 S NADPH-dependent FMN reductase
JFDLEHCO_02854 6.5e-119 ycaC Q Isochorismatase family
JFDLEHCO_02855 7.4e-230 yugK C Dehydrogenase
JFDLEHCO_02856 1.2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
JFDLEHCO_02857 1.8e-34 yuzA S Domain of unknown function (DUF378)
JFDLEHCO_02858 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
JFDLEHCO_02859 1.2e-211 yugH 2.6.1.1 E Aminotransferase
JFDLEHCO_02860 2e-83 alaR K Transcriptional regulator
JFDLEHCO_02861 3.8e-156 yugF I Hydrolase
JFDLEHCO_02862 1.4e-40 yugE S Domain of unknown function (DUF1871)
JFDLEHCO_02863 8.4e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JFDLEHCO_02864 5.6e-231 T PhoQ Sensor
JFDLEHCO_02865 3.7e-69 kapB G Kinase associated protein B
JFDLEHCO_02866 4.5e-118 kapD L the KinA pathway to sporulation
JFDLEHCO_02867 1.5e-185 yuxJ EGP Major facilitator Superfamily
JFDLEHCO_02868 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
JFDLEHCO_02869 1.7e-72 yuxK S protein conserved in bacteria
JFDLEHCO_02870 9.3e-74 yufK S Family of unknown function (DUF5366)
JFDLEHCO_02871 1.5e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JFDLEHCO_02872 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
JFDLEHCO_02873 8.3e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
JFDLEHCO_02874 4.5e-288 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
JFDLEHCO_02875 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
JFDLEHCO_02876 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
JFDLEHCO_02877 1.8e-12
JFDLEHCO_02878 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
JFDLEHCO_02879 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JFDLEHCO_02880 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JFDLEHCO_02881 1.2e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JFDLEHCO_02882 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JFDLEHCO_02883 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JFDLEHCO_02884 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
JFDLEHCO_02885 3.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
JFDLEHCO_02886 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JFDLEHCO_02887 0.0 comP 2.7.13.3 T Histidine kinase
JFDLEHCO_02889 6.3e-154 comQ H Polyprenyl synthetase
JFDLEHCO_02891 3e-54 yuzC
JFDLEHCO_02892 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
JFDLEHCO_02893 2.5e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JFDLEHCO_02894 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
JFDLEHCO_02895 7.2e-68 yueI S Protein of unknown function (DUF1694)
JFDLEHCO_02896 2.8e-38 yueH S YueH-like protein
JFDLEHCO_02897 6.4e-34 yueG S Spore germination protein gerPA/gerPF
JFDLEHCO_02898 3e-188 yueF S transporter activity
JFDLEHCO_02899 1.6e-22 S Protein of unknown function (DUF2642)
JFDLEHCO_02900 3.7e-96 yueE S phosphohydrolase
JFDLEHCO_02901 5.8e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JFDLEHCO_02902 1.8e-78 yueC S Family of unknown function (DUF5383)
JFDLEHCO_02903 0.0 esaA S type VII secretion protein EsaA
JFDLEHCO_02904 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
JFDLEHCO_02905 7.4e-207 essB S WXG100 protein secretion system (Wss), protein YukC
JFDLEHCO_02906 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
JFDLEHCO_02907 3.3e-46 esxA S Belongs to the WXG100 family
JFDLEHCO_02908 4.5e-230 yukF QT Transcriptional regulator
JFDLEHCO_02909 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
JFDLEHCO_02910 6.8e-135 yukJ S Uncharacterized conserved protein (DUF2278)
JFDLEHCO_02911 1.3e-36 mbtH S MbtH-like protein
JFDLEHCO_02912 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_02913 6.3e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
JFDLEHCO_02914 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
JFDLEHCO_02915 1.1e-225 entC 5.4.4.2 HQ Isochorismate synthase
JFDLEHCO_02916 1.1e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JFDLEHCO_02917 1.5e-166 besA S Putative esterase
JFDLEHCO_02918 1.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
JFDLEHCO_02919 1.1e-101 bioY S Biotin biosynthesis protein
JFDLEHCO_02920 3.7e-209 yuiF S antiporter
JFDLEHCO_02921 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JFDLEHCO_02922 9.1e-78 yuiD S protein conserved in bacteria
JFDLEHCO_02923 1.4e-118 yuiC S protein conserved in bacteria
JFDLEHCO_02924 9.9e-28 yuiB S Putative membrane protein
JFDLEHCO_02925 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
JFDLEHCO_02926 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
JFDLEHCO_02928 4.2e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JFDLEHCO_02929 4.8e-29
JFDLEHCO_02930 3.7e-72 CP Membrane
JFDLEHCO_02931 1.5e-124 V ABC transporter
JFDLEHCO_02933 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
JFDLEHCO_02935 2.9e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
JFDLEHCO_02936 7.8e-140 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
JFDLEHCO_02937 1.1e-62 erpA S Belongs to the HesB IscA family
JFDLEHCO_02938 5.7e-163 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JFDLEHCO_02939 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JFDLEHCO_02940 2.4e-39 yuzB S Belongs to the UPF0349 family
JFDLEHCO_02941 8.5e-209 yutJ 1.6.99.3 C NADH dehydrogenase
JFDLEHCO_02942 4.7e-57 yuzD S protein conserved in bacteria
JFDLEHCO_02943 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
JFDLEHCO_02944 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
JFDLEHCO_02945 1e-170 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JFDLEHCO_02946 4e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JFDLEHCO_02947 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
JFDLEHCO_02948 1.4e-197 yutH S Spore coat protein
JFDLEHCO_02949 3e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
JFDLEHCO_02950 8.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JFDLEHCO_02951 8.6e-75 yutE S Protein of unknown function DUF86
JFDLEHCO_02952 1.7e-47 yutD S protein conserved in bacteria
JFDLEHCO_02953 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JFDLEHCO_02954 5.8e-196 lytH M Peptidase, M23
JFDLEHCO_02955 6e-132 yunB S Sporulation protein YunB (Spo_YunB)
JFDLEHCO_02956 2.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JFDLEHCO_02957 1.8e-145 yunE S membrane transporter protein
JFDLEHCO_02958 1.3e-170 yunF S Protein of unknown function DUF72
JFDLEHCO_02959 4.7e-63 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
JFDLEHCO_02960 8.8e-267 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
JFDLEHCO_02961 2.1e-304 pucR QT COG2508 Regulator of polyketide synthase expression
JFDLEHCO_02962 4.3e-74
JFDLEHCO_02964 1.5e-214 blt EGP Major facilitator Superfamily
JFDLEHCO_02965 4.9e-240 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
JFDLEHCO_02966 1.9e-239 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
JFDLEHCO_02967 1.1e-169 bsn L Ribonuclease
JFDLEHCO_02968 2.3e-209 msmX P Belongs to the ABC transporter superfamily
JFDLEHCO_02969 1.2e-134 yurK K UTRA
JFDLEHCO_02970 6.3e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
JFDLEHCO_02971 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
JFDLEHCO_02972 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
JFDLEHCO_02973 3.3e-247 yurO G COG1653 ABC-type sugar transport system, periplasmic component
JFDLEHCO_02974 1.9e-186 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
JFDLEHCO_02975 1.2e-166 K helix_turn_helix, mercury resistance
JFDLEHCO_02978 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
JFDLEHCO_02979 3.2e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
JFDLEHCO_02980 1.8e-130 Q ubiE/COQ5 methyltransferase family
JFDLEHCO_02981 1.5e-85 yncE S Protein of unknown function (DUF2691)
JFDLEHCO_02982 2e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
JFDLEHCO_02983 3e-270 sufB O FeS cluster assembly
JFDLEHCO_02984 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
JFDLEHCO_02985 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JFDLEHCO_02986 7e-245 sufD O assembly protein SufD
JFDLEHCO_02987 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
JFDLEHCO_02988 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JFDLEHCO_02989 2.3e-145 metQ P Belongs to the NlpA lipoprotein family
JFDLEHCO_02990 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
JFDLEHCO_02991 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JFDLEHCO_02992 5e-57 yusD S SCP-2 sterol transfer family
JFDLEHCO_02993 1.6e-54 yusE CO Thioredoxin
JFDLEHCO_02994 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
JFDLEHCO_02995 1.3e-40 yusG S Protein of unknown function (DUF2553)
JFDLEHCO_02996 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
JFDLEHCO_02997 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
JFDLEHCO_02998 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
JFDLEHCO_02999 1.1e-217 fadA 2.3.1.16 I Belongs to the thiolase family
JFDLEHCO_03000 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
JFDLEHCO_03001 3.6e-168 fadM E Proline dehydrogenase
JFDLEHCO_03002 1.4e-43
JFDLEHCO_03003 1.1e-53 yusN M Coat F domain
JFDLEHCO_03004 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
JFDLEHCO_03005 8.1e-288 yusP P Major facilitator superfamily
JFDLEHCO_03006 3.1e-68 yusQ S Tautomerase enzyme
JFDLEHCO_03007 1.4e-133 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JFDLEHCO_03008 1e-159 yusT K LysR substrate binding domain
JFDLEHCO_03009 4.2e-161 ywbI2 K Transcriptional regulator
JFDLEHCO_03010 4.1e-141 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
JFDLEHCO_03011 1.7e-190 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JFDLEHCO_03012 3.3e-39 yusU S Protein of unknown function (DUF2573)
JFDLEHCO_03013 1.4e-150 yusV 3.6.3.34 HP ABC transporter
JFDLEHCO_03014 7.2e-45 S YusW-like protein
JFDLEHCO_03015 0.0 pepF2 E COG1164 Oligoendopeptidase F
JFDLEHCO_03016 9.6e-155 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JFDLEHCO_03017 6.7e-81 dps P Belongs to the Dps family
JFDLEHCO_03018 7.5e-242 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JFDLEHCO_03019 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JFDLEHCO_03020 2.5e-253 cssS 2.7.13.3 T PhoQ Sensor
JFDLEHCO_03021 3.4e-24
JFDLEHCO_03022 2.7e-158 yuxN K Transcriptional regulator
JFDLEHCO_03023 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
JFDLEHCO_03024 6.6e-24 S Protein of unknown function (DUF3970)
JFDLEHCO_03025 2.2e-260 gerAA EG Spore germination protein
JFDLEHCO_03026 2e-189 gerAB E Spore germination protein
JFDLEHCO_03027 7.3e-211 gerAC S Spore germination B3/ GerAC like, C-terminal
JFDLEHCO_03028 1.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JFDLEHCO_03029 1e-193 vraS 2.7.13.3 T Histidine kinase
JFDLEHCO_03030 1.7e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
JFDLEHCO_03031 2.7e-144 liaG S Putative adhesin
JFDLEHCO_03032 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
JFDLEHCO_03033 3.3e-46 liaI S membrane
JFDLEHCO_03034 4.7e-230 yvqJ EGP Major facilitator Superfamily
JFDLEHCO_03035 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
JFDLEHCO_03036 2.1e-227 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
JFDLEHCO_03037 6.7e-182 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFDLEHCO_03038 1.1e-167 yvrC P ABC transporter substrate-binding protein
JFDLEHCO_03039 1.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JFDLEHCO_03040 2e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
JFDLEHCO_03041 0.0 T PhoQ Sensor
JFDLEHCO_03042 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JFDLEHCO_03043 1.1e-36
JFDLEHCO_03044 9.9e-103 yvrI K RNA polymerase
JFDLEHCO_03045 1.6e-15 S YvrJ protein family
JFDLEHCO_03046 5.4e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
JFDLEHCO_03047 4.4e-68 yvrL S Regulatory protein YrvL
JFDLEHCO_03048 4.8e-148 fhuC 3.6.3.34 HP ABC transporter
JFDLEHCO_03049 1.1e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFDLEHCO_03050 6.6e-185 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFDLEHCO_03051 4e-178 fhuD P ABC transporter
JFDLEHCO_03052 1.3e-236 yvsH E Arginine ornithine antiporter
JFDLEHCO_03053 1e-13 S Small spore protein J (Spore_SspJ)
JFDLEHCO_03054 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
JFDLEHCO_03055 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JFDLEHCO_03056 1.8e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
JFDLEHCO_03057 2.2e-140 modA P COG0725 ABC-type molybdate transport system, periplasmic component
JFDLEHCO_03058 2.7e-99 modB P COG4149 ABC-type molybdate transport system, permease component
JFDLEHCO_03059 4.4e-115 yfiK K Regulator
JFDLEHCO_03060 4.9e-183 T Histidine kinase
JFDLEHCO_03061 1.9e-172 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
JFDLEHCO_03062 2.5e-195 yfiM V ABC-2 type transporter
JFDLEHCO_03063 1.4e-201 yfiN V COG0842 ABC-type multidrug transport system, permease component
JFDLEHCO_03064 5e-156 yvgN S reductase
JFDLEHCO_03065 4.9e-87 yvgO
JFDLEHCO_03066 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
JFDLEHCO_03067 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
JFDLEHCO_03068 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JFDLEHCO_03069 0.0 helD 3.6.4.12 L DNA helicase
JFDLEHCO_03070 9.1e-107 yvgT S membrane
JFDLEHCO_03071 6.1e-143 S Metallo-peptidase family M12
JFDLEHCO_03072 2e-73 bdbC O Required for disulfide bond formation in some proteins
JFDLEHCO_03073 1.2e-102 bdbD O Thioredoxin
JFDLEHCO_03074 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
JFDLEHCO_03075 0.0 copA 3.6.3.54 P P-type ATPase
JFDLEHCO_03076 2.6e-29 copZ P Heavy-metal-associated domain
JFDLEHCO_03077 3.7e-48 csoR S transcriptional
JFDLEHCO_03078 7.3e-197 yvaA 1.1.1.371 S Oxidoreductase
JFDLEHCO_03079 1.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JFDLEHCO_03080 1.1e-163 K Helix-turn-helix XRE-family like proteins
JFDLEHCO_03081 2.9e-221 ynfM EGP Major Facilitator Superfamily
JFDLEHCO_03082 1.2e-70 4.1.1.44 S Carboxymuconolactone decarboxylase family
JFDLEHCO_03083 1.4e-147 S Amidohydrolase
JFDLEHCO_03084 4.7e-257 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JFDLEHCO_03085 5.9e-48 ytnI O COG0695 Glutaredoxin and related proteins
JFDLEHCO_03086 2.9e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JFDLEHCO_03087 6.6e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JFDLEHCO_03088 1.3e-120 tcyM U Binding-protein-dependent transport system inner membrane component
JFDLEHCO_03089 1.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
JFDLEHCO_03090 9.9e-149 tcyK M Bacterial periplasmic substrate-binding proteins
JFDLEHCO_03091 7.4e-132 ytmJ ET Bacterial periplasmic substrate-binding proteins
JFDLEHCO_03092 1.7e-101 ytmI K Acetyltransferase (GNAT) domain
JFDLEHCO_03093 4.8e-165 ytlI K LysR substrate binding domain
JFDLEHCO_03094 1.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JFDLEHCO_03095 2.9e-53 yrdF K ribonuclease inhibitor
JFDLEHCO_03097 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JFDLEHCO_03098 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JFDLEHCO_03099 7.4e-143 est 3.1.1.1 S Carboxylesterase
JFDLEHCO_03100 4.8e-24 secG U Preprotein translocase subunit SecG
JFDLEHCO_03101 6e-35 yvzC K Transcriptional
JFDLEHCO_03102 1e-69 K transcriptional
JFDLEHCO_03103 2.7e-73 yvaO K Cro/C1-type HTH DNA-binding domain
JFDLEHCO_03104 8.8e-53 yodB K transcriptional
JFDLEHCO_03105 2.2e-260 T His Kinase A (phosphoacceptor) domain
JFDLEHCO_03106 2e-123 K Transcriptional regulatory protein, C terminal
JFDLEHCO_03107 1.9e-141 mutG S ABC-2 family transporter protein
JFDLEHCO_03108 2.5e-127 spaE S ABC-2 family transporter protein
JFDLEHCO_03109 2.5e-127 mutF V ABC transporter, ATP-binding protein
JFDLEHCO_03110 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
JFDLEHCO_03111 2.6e-174 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JFDLEHCO_03112 5.4e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
JFDLEHCO_03113 3.4e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
JFDLEHCO_03114 4.3e-76 yvbF K Belongs to the GbsR family
JFDLEHCO_03115 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
JFDLEHCO_03116 2.2e-173 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JFDLEHCO_03117 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
JFDLEHCO_03118 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
JFDLEHCO_03119 1.9e-98 yvbF K Belongs to the GbsR family
JFDLEHCO_03120 5.2e-105 yvbG U UPF0056 membrane protein
JFDLEHCO_03121 4.5e-121 exoY M Membrane
JFDLEHCO_03122 0.0 tcaA S response to antibiotic
JFDLEHCO_03123 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
JFDLEHCO_03124 3.5e-214 EGP Major facilitator Superfamily
JFDLEHCO_03125 2.2e-181
JFDLEHCO_03126 1.2e-126 S GlcNAc-PI de-N-acetylase
JFDLEHCO_03127 2.5e-143 C WbqC-like protein family
JFDLEHCO_03128 1.2e-150 M Protein involved in cellulose biosynthesis
JFDLEHCO_03129 2.2e-240 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JFDLEHCO_03130 8.6e-173 5.1.3.2 M GDP-mannose 4,6 dehydratase
JFDLEHCO_03131 1.3e-218 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
JFDLEHCO_03132 2.8e-257 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JFDLEHCO_03133 7.8e-241 ywaD 3.4.11.10, 3.4.11.6 S PA domain
JFDLEHCO_03134 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JFDLEHCO_03135 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
JFDLEHCO_03136 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JFDLEHCO_03137 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JFDLEHCO_03138 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JFDLEHCO_03139 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
JFDLEHCO_03141 7.4e-253 araE EGP Major facilitator Superfamily
JFDLEHCO_03142 3.4e-205 araR K transcriptional
JFDLEHCO_03143 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JFDLEHCO_03145 2.1e-157 yvbU K Transcriptional regulator
JFDLEHCO_03146 9.1e-159 yvbV EG EamA-like transporter family
JFDLEHCO_03147 1.7e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
JFDLEHCO_03148 4e-261
JFDLEHCO_03149 1.7e-184 purR7 5.1.1.1 K Transcriptional regulator
JFDLEHCO_03150 6.9e-116 yyaS S Membrane
JFDLEHCO_03151 6.1e-168 3.1.3.104 S hydrolases of the HAD superfamily
JFDLEHCO_03152 9.1e-153 ybbH_1 K RpiR family transcriptional regulator
JFDLEHCO_03153 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
JFDLEHCO_03154 4.3e-226 gntP EG COG2610 H gluconate symporter and related permeases
JFDLEHCO_03155 3.6e-134 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
JFDLEHCO_03156 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
JFDLEHCO_03157 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
JFDLEHCO_03158 2e-227 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JFDLEHCO_03159 1.6e-121 yvfI K COG2186 Transcriptional regulators
JFDLEHCO_03160 3.4e-305 yvfH C L-lactate permease
JFDLEHCO_03161 1.8e-245 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
JFDLEHCO_03162 1.6e-32 yvfG S YvfG protein
JFDLEHCO_03163 3.6e-190 yvfF GM Exopolysaccharide biosynthesis protein
JFDLEHCO_03164 5.7e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
JFDLEHCO_03165 1.1e-57 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
JFDLEHCO_03166 3.4e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
JFDLEHCO_03167 8.2e-274 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JFDLEHCO_03168 7.8e-199 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
JFDLEHCO_03169 4.7e-207 epsI GM pyruvyl transferase
JFDLEHCO_03170 1.2e-196 epsH GT2 S Glycosyltransferase like family 2
JFDLEHCO_03171 4.1e-206 epsG S EpsG family
JFDLEHCO_03172 3.1e-217 epsF GT4 M Glycosyl transferases group 1
JFDLEHCO_03173 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JFDLEHCO_03174 1.7e-223 epsD GT4 M Glycosyl transferase 4-like
JFDLEHCO_03175 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
JFDLEHCO_03176 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
JFDLEHCO_03177 2.2e-120 ywqC M biosynthesis protein
JFDLEHCO_03178 5.1e-78 slr K transcriptional
JFDLEHCO_03179 1.6e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
JFDLEHCO_03180 1.4e-98 ywjB H RibD C-terminal domain
JFDLEHCO_03181 4e-113 yyaS S Membrane
JFDLEHCO_03182 6.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JFDLEHCO_03183 5.5e-94 padC Q Phenolic acid decarboxylase
JFDLEHCO_03184 2e-16 S Protein of unknown function (DUF1433)
JFDLEHCO_03185 4.8e-41 S Protein of unknown function (DUF1433)
JFDLEHCO_03186 1.6e-46 I Pfam Lipase (class 3)
JFDLEHCO_03187 1.8e-16 S Protein of unknown function (DUF1433)
JFDLEHCO_03188 5.9e-274 I Pfam Lipase (class 3)
JFDLEHCO_03189 1.8e-34
JFDLEHCO_03191 9.4e-299 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
JFDLEHCO_03192 7.3e-220 rafB P LacY proton/sugar symporter
JFDLEHCO_03193 1e-184 scrR K transcriptional
JFDLEHCO_03194 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JFDLEHCO_03195 6.7e-164 yraN K Transcriptional regulator
JFDLEHCO_03196 4.5e-216 yraM S PrpF protein
JFDLEHCO_03197 1.6e-252 EGP Sugar (and other) transporter
JFDLEHCO_03198 5.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
JFDLEHCO_03199 2.3e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
JFDLEHCO_03200 3.9e-282 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
JFDLEHCO_03201 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
JFDLEHCO_03202 5e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JFDLEHCO_03203 1.6e-79 M Ribonuclease
JFDLEHCO_03204 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
JFDLEHCO_03205 1.2e-36 crh G Phosphocarrier protein Chr
JFDLEHCO_03206 3.1e-170 whiA K May be required for sporulation
JFDLEHCO_03207 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JFDLEHCO_03208 1.1e-166 rapZ S Displays ATPase and GTPase activities
JFDLEHCO_03209 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
JFDLEHCO_03210 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JFDLEHCO_03211 2.7e-125 usp CBM50 M protein conserved in bacteria
JFDLEHCO_03212 1e-276 S COG0457 FOG TPR repeat
JFDLEHCO_03213 2.9e-193 sasA T Histidine kinase
JFDLEHCO_03214 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JFDLEHCO_03215 0.0 msbA2 3.6.3.44 V ABC transporter
JFDLEHCO_03216 3.3e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
JFDLEHCO_03217 9.6e-138 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JFDLEHCO_03218 3.4e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JFDLEHCO_03219 6e-117 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JFDLEHCO_03220 3e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
JFDLEHCO_03221 7e-237 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JFDLEHCO_03222 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JFDLEHCO_03223 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JFDLEHCO_03224 1.8e-138 yvpB NU protein conserved in bacteria
JFDLEHCO_03225 5.4e-84 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
JFDLEHCO_03226 1.7e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
JFDLEHCO_03227 1.2e-151 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JFDLEHCO_03228 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JFDLEHCO_03229 9.2e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JFDLEHCO_03230 1.2e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JFDLEHCO_03231 1.1e-133 yvoA K transcriptional
JFDLEHCO_03232 1.2e-105 yxaF K Transcriptional regulator
JFDLEHCO_03233 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
JFDLEHCO_03234 3.9e-41 yvlD S Membrane
JFDLEHCO_03235 9.6e-26 pspB KT PspC domain
JFDLEHCO_03236 3.2e-166 yvlB S Putative adhesin
JFDLEHCO_03237 6.1e-49 yvlA
JFDLEHCO_03238 3e-38 yvkN
JFDLEHCO_03239 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
JFDLEHCO_03240 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JFDLEHCO_03241 7.6e-33 csbA S protein conserved in bacteria
JFDLEHCO_03242 0.0 yvkC 2.7.9.2 GT Phosphotransferase
JFDLEHCO_03243 2.4e-110 yvkB K Transcriptional regulator
JFDLEHCO_03244 3e-227 yvkA EGP Major facilitator Superfamily
JFDLEHCO_03245 5.2e-223 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JFDLEHCO_03246 4.1e-56 swrA S Swarming motility protein
JFDLEHCO_03247 5e-257 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
JFDLEHCO_03248 8.8e-230 ywoF P Right handed beta helix region
JFDLEHCO_03249 1.7e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
JFDLEHCO_03250 1e-122 ftsE D cell division ATP-binding protein FtsE
JFDLEHCO_03251 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
JFDLEHCO_03252 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
JFDLEHCO_03253 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JFDLEHCO_03254 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JFDLEHCO_03255 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JFDLEHCO_03256 6.8e-68
JFDLEHCO_03257 5.3e-11 fliT S bacterial-type flagellum organization
JFDLEHCO_03258 3e-66 fliS N flagellar protein FliS
JFDLEHCO_03259 4.3e-262 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JFDLEHCO_03260 3.9e-116 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JFDLEHCO_03261 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JFDLEHCO_03262 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JFDLEHCO_03263 1.2e-81 yviE
JFDLEHCO_03264 6.1e-163 flgL N Belongs to the bacterial flagellin family
JFDLEHCO_03265 4.4e-275 flgK N flagellar hook-associated protein
JFDLEHCO_03266 8.9e-81 flgN NOU FlgN protein
JFDLEHCO_03267 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
JFDLEHCO_03268 1.4e-74 yvyF S flagellar protein
JFDLEHCO_03269 1.1e-78 comFC S Phosphoribosyl transferase domain
JFDLEHCO_03270 1.5e-43 comFB S Late competence development protein ComFB
JFDLEHCO_03271 8.1e-268 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JFDLEHCO_03272 1.4e-158 degV S protein conserved in bacteria
JFDLEHCO_03273 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JFDLEHCO_03274 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
JFDLEHCO_03275 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
JFDLEHCO_03276 3e-173 yvhJ K Transcriptional regulator
JFDLEHCO_03277 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
JFDLEHCO_03278 1.2e-240 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
JFDLEHCO_03279 6.8e-144 tuaG GT2 M Glycosyltransferase like family 2
JFDLEHCO_03280 6.4e-117 tuaF M protein involved in exopolysaccharide biosynthesis
JFDLEHCO_03281 1.7e-260 tuaE M Teichuronic acid biosynthesis protein
JFDLEHCO_03282 7.8e-252 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JFDLEHCO_03283 3.9e-226 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
JFDLEHCO_03284 9.3e-259 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JFDLEHCO_03285 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
JFDLEHCO_03286 5.4e-270 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JFDLEHCO_03287 0.0 lytB 3.5.1.28 D Stage II sporulation protein
JFDLEHCO_03288 5.9e-49
JFDLEHCO_03289 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
JFDLEHCO_03290 6.7e-212 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JFDLEHCO_03291 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JFDLEHCO_03292 4e-284 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JFDLEHCO_03293 1.7e-151 tagG GM Transport permease protein
JFDLEHCO_03294 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JFDLEHCO_03295 8.6e-295 M Glycosyltransferase like family 2
JFDLEHCO_03296 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
JFDLEHCO_03297 1.5e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
JFDLEHCO_03298 3.7e-221 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JFDLEHCO_03299 1.7e-245 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JFDLEHCO_03300 2.5e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
JFDLEHCO_03301 9.3e-267 gerBA EG Spore germination protein
JFDLEHCO_03302 6.8e-201 gerBB E Spore germination protein
JFDLEHCO_03303 6.5e-215 gerAC S Spore germination protein
JFDLEHCO_03304 8.6e-270 GT2,GT4 J Glycosyl transferase family 2
JFDLEHCO_03305 3.7e-249 ywtG EGP Major facilitator Superfamily
JFDLEHCO_03306 3.8e-179 ywtF K Transcriptional regulator
JFDLEHCO_03307 4.5e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
JFDLEHCO_03308 2.9e-38 yttA 2.7.13.3 S Pfam Transposase IS66
JFDLEHCO_03309 5.2e-242 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
JFDLEHCO_03310 1.3e-20 ywtC
JFDLEHCO_03311 1.2e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
JFDLEHCO_03312 2.3e-70 pgsC S biosynthesis protein
JFDLEHCO_03313 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
JFDLEHCO_03314 1.1e-124 gerAA P Bacillus/Clostridium GerA spore germination protein
JFDLEHCO_03315 6.7e-193 gerKB E Spore germination protein
JFDLEHCO_03316 5.5e-206 gerKC S Spore germination B3/ GerAC like, C-terminal
JFDLEHCO_03317 1.8e-181 rbsR K transcriptional
JFDLEHCO_03318 6.1e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JFDLEHCO_03319 4.3e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
JFDLEHCO_03320 3.4e-280 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
JFDLEHCO_03321 2.9e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
JFDLEHCO_03322 5.2e-162 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
JFDLEHCO_03323 1.4e-90 batE T Sh3 type 3 domain protein
JFDLEHCO_03324 2.2e-96 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
JFDLEHCO_03325 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
JFDLEHCO_03326 2.4e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JFDLEHCO_03327 9e-167 alsR K LysR substrate binding domain
JFDLEHCO_03328 1.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JFDLEHCO_03329 4.4e-126 ywrJ
JFDLEHCO_03330 4.4e-134 cotB
JFDLEHCO_03331 4.1e-214 cotH M Spore Coat
JFDLEHCO_03332 2e-09
JFDLEHCO_03333 2.5e-112 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JFDLEHCO_03334 2e-307 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
JFDLEHCO_03335 1.1e-83 ywrC K Transcriptional regulator
JFDLEHCO_03336 8.3e-105 ywrB P Chromate transporter
JFDLEHCO_03337 2e-89 ywrA P COG2059 Chromate transport protein ChrA
JFDLEHCO_03338 1.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
JFDLEHCO_03339 1.6e-93
JFDLEHCO_03340 4.6e-48 S SMI1 / KNR4 family (SUKH-1)
JFDLEHCO_03341 3.8e-104 S Domain of unknown function (DUF1851)
JFDLEHCO_03342 3.4e-79 S LXG domain of WXG superfamily
JFDLEHCO_03343 6.3e-93
JFDLEHCO_03344 2e-49
JFDLEHCO_03345 0.0 ywqJ S Pre-toxin TG
JFDLEHCO_03346 4.3e-37 ywqI S Family of unknown function (DUF5344)
JFDLEHCO_03347 8.5e-22 S Domain of unknown function (DUF5082)
JFDLEHCO_03349 9.9e-154 ywqG S Domain of unknown function (DUF1963)
JFDLEHCO_03350 9.5e-250 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JFDLEHCO_03351 1.7e-142 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
JFDLEHCO_03352 6.7e-122 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
JFDLEHCO_03353 5.2e-112 ywqC M biosynthesis protein
JFDLEHCO_03354 1.3e-14
JFDLEHCO_03355 2.2e-309 ywqB S SWIM zinc finger
JFDLEHCO_03356 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
JFDLEHCO_03357 2.5e-158 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
JFDLEHCO_03358 7.5e-138 glcR K DeoR C terminal sensor domain
JFDLEHCO_03359 7.5e-58 ssbB L Single-stranded DNA-binding protein
JFDLEHCO_03360 4e-62 ywpG
JFDLEHCO_03361 3.9e-69 ywpF S YwpF-like protein
JFDLEHCO_03362 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JFDLEHCO_03363 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JFDLEHCO_03364 1.3e-201 S aspartate phosphatase
JFDLEHCO_03365 6.1e-146 flhP N flagellar basal body
JFDLEHCO_03366 3.2e-128 flhO N flagellar basal body
JFDLEHCO_03367 2.7e-180 mbl D Rod shape-determining protein
JFDLEHCO_03368 1.8e-44 spoIIID K Stage III sporulation protein D
JFDLEHCO_03369 8.5e-72 ywoH K transcriptional
JFDLEHCO_03370 3.8e-213 ywoG EGP Major facilitator Superfamily
JFDLEHCO_03371 1.9e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
JFDLEHCO_03372 7.2e-245 ywoD EGP Major facilitator superfamily
JFDLEHCO_03373 5.7e-103 phzA Q Isochorismatase family
JFDLEHCO_03374 2.5e-228 amt P Ammonium transporter
JFDLEHCO_03375 2e-58 nrgB K Belongs to the P(II) protein family
JFDLEHCO_03376 2.2e-210 ftsW D Belongs to the SEDS family
JFDLEHCO_03377 3.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
JFDLEHCO_03378 1.7e-72 ywnJ S VanZ like family
JFDLEHCO_03379 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
JFDLEHCO_03380 4.9e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
JFDLEHCO_03381 1.2e-10 ywnC S Family of unknown function (DUF5362)
JFDLEHCO_03382 4.2e-69 ywnF S Family of unknown function (DUF5392)
JFDLEHCO_03383 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JFDLEHCO_03384 4.4e-54 ywnC S Family of unknown function (DUF5362)
JFDLEHCO_03385 3.1e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
JFDLEHCO_03386 2.1e-67 ywnA K Transcriptional regulator
JFDLEHCO_03387 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
JFDLEHCO_03388 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
JFDLEHCO_03389 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
JFDLEHCO_03390 6.5e-11 csbD K CsbD-like
JFDLEHCO_03391 9.5e-83 ywmF S Peptidase M50
JFDLEHCO_03392 2.8e-93 S response regulator aspartate phosphatase
JFDLEHCO_03393 1.8e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JFDLEHCO_03394 2e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JFDLEHCO_03396 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
JFDLEHCO_03397 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
JFDLEHCO_03398 1.9e-189 spoIID D Stage II sporulation protein D
JFDLEHCO_03399 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JFDLEHCO_03400 6.7e-136 ywmB S TATA-box binding
JFDLEHCO_03401 1.3e-32 ywzB S membrane
JFDLEHCO_03402 1.2e-90 ywmA
JFDLEHCO_03403 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JFDLEHCO_03404 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JFDLEHCO_03405 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JFDLEHCO_03406 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JFDLEHCO_03407 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JFDLEHCO_03408 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JFDLEHCO_03409 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JFDLEHCO_03410 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
JFDLEHCO_03411 2.1e-61 atpI S ATP synthase
JFDLEHCO_03412 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JFDLEHCO_03413 1.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JFDLEHCO_03414 5.9e-97 ywlG S Belongs to the UPF0340 family
JFDLEHCO_03415 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
JFDLEHCO_03416 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JFDLEHCO_03417 4.5e-92 mntP P Probably functions as a manganese efflux pump
JFDLEHCO_03418 3.2e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JFDLEHCO_03419 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
JFDLEHCO_03420 1.5e-121 spoIIR S stage II sporulation protein R
JFDLEHCO_03421 1e-60 ywlA S Uncharacterised protein family (UPF0715)
JFDLEHCO_03423 5.5e-158 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JFDLEHCO_03424 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JFDLEHCO_03425 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JFDLEHCO_03426 6.7e-96 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
JFDLEHCO_03427 3.6e-158 ywkB S Membrane transport protein
JFDLEHCO_03428 0.0 sfcA 1.1.1.38 C malic enzyme
JFDLEHCO_03429 1.4e-104 tdk 2.7.1.21 F thymidine kinase
JFDLEHCO_03430 1.1e-32 rpmE J Binds the 23S rRNA
JFDLEHCO_03431 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JFDLEHCO_03432 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
JFDLEHCO_03433 5.1e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JFDLEHCO_03434 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JFDLEHCO_03435 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
JFDLEHCO_03436 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
JFDLEHCO_03437 1.7e-93 ywjG S Domain of unknown function (DUF2529)
JFDLEHCO_03438 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JFDLEHCO_03439 2.2e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JFDLEHCO_03440 0.0 fadF C COG0247 Fe-S oxidoreductase
JFDLEHCO_03441 1.3e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
JFDLEHCO_03442 7.7e-185 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
JFDLEHCO_03443 2.4e-43 ywjC
JFDLEHCO_03444 0.0 ywjA V ABC transporter
JFDLEHCO_03445 9.6e-302 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JFDLEHCO_03446 2.8e-106 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JFDLEHCO_03447 2.4e-124 narI 1.7.5.1 C nitrate reductase, gamma
JFDLEHCO_03448 1.9e-98 narJ 1.7.5.1 C nitrate reductase
JFDLEHCO_03449 1.8e-294 narH 1.7.5.1 C Nitrate reductase, beta
JFDLEHCO_03450 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JFDLEHCO_03451 2e-85 arfM T cyclic nucleotide binding
JFDLEHCO_03452 5.1e-141 ywiC S YwiC-like protein
JFDLEHCO_03453 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
JFDLEHCO_03454 5.8e-214 narK P COG2223 Nitrate nitrite transporter
JFDLEHCO_03455 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
JFDLEHCO_03456 1.2e-73 ywiB S protein conserved in bacteria
JFDLEHCO_03458 1.4e-232 ywhL CO amine dehydrogenase activity
JFDLEHCO_03459 1.3e-222 ywhK CO amine dehydrogenase activity
JFDLEHCO_03460 2.4e-76 S aspartate phosphatase
JFDLEHCO_03462 2.6e-29 ydcG K sequence-specific DNA binding
JFDLEHCO_03463 5e-33
JFDLEHCO_03464 2e-28 S Domain of unknown function (DUF4177)
JFDLEHCO_03466 3.6e-77 CP Membrane
JFDLEHCO_03469 5.4e-169 speB 3.5.3.11 E Belongs to the arginase family
JFDLEHCO_03470 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JFDLEHCO_03471 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JFDLEHCO_03472 3.5e-84
JFDLEHCO_03473 1.4e-95 ywhD S YwhD family
JFDLEHCO_03474 1.1e-118 ywhC S Peptidase family M50
JFDLEHCO_03475 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
JFDLEHCO_03476 3.6e-70 ywhA K Transcriptional regulator
JFDLEHCO_03477 1.6e-247 yhdG_1 E C-terminus of AA_permease
JFDLEHCO_03478 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
JFDLEHCO_03479 7.9e-257 ywfO S COG1078 HD superfamily phosphohydrolases
JFDLEHCO_03480 6.9e-36 ywzC S Belongs to the UPF0741 family
JFDLEHCO_03481 3e-110 rsfA_1
JFDLEHCO_03482 7.4e-52 padR K PadR family transcriptional regulator
JFDLEHCO_03483 8.1e-94 S membrane
JFDLEHCO_03484 9.1e-167 V ABC transporter, ATP-binding protein
JFDLEHCO_03485 3.5e-169 yhcI S ABC transporter (permease)
JFDLEHCO_03488 1.2e-179
JFDLEHCO_03490 2.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
JFDLEHCO_03491 6e-163 cysL K Transcriptional regulator
JFDLEHCO_03492 7.9e-161 MA20_14895 S Conserved hypothetical protein 698
JFDLEHCO_03493 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
JFDLEHCO_03494 1.1e-146 ywfI C May function as heme-dependent peroxidase
JFDLEHCO_03495 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
JFDLEHCO_03496 2.1e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
JFDLEHCO_03497 1.2e-208 bacE EGP Major facilitator Superfamily
JFDLEHCO_03498 2e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
JFDLEHCO_03499 4.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JFDLEHCO_03500 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
JFDLEHCO_03501 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
JFDLEHCO_03502 2.6e-225 ywfA EGP Major facilitator Superfamily
JFDLEHCO_03503 4.3e-209 tcaB EGP Major facilitator Superfamily
JFDLEHCO_03504 7.5e-261 lysP E amino acid
JFDLEHCO_03505 0.0 rocB E arginine degradation protein
JFDLEHCO_03506 5.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
JFDLEHCO_03507 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
JFDLEHCO_03508 1.5e-164 T PhoQ Sensor
JFDLEHCO_03509 3.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JFDLEHCO_03510 4.9e-45 S Putative adhesin
JFDLEHCO_03511 3.9e-84
JFDLEHCO_03512 2.9e-120 S ABC-2 family transporter protein
JFDLEHCO_03513 6.7e-173 bcrA5 V ABC transporter, ATP-binding protein
JFDLEHCO_03514 2.7e-87 spsL 5.1.3.13 M Spore Coat
JFDLEHCO_03515 1.3e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JFDLEHCO_03516 9.3e-183 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JFDLEHCO_03517 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JFDLEHCO_03518 2.9e-190 spsG M Spore Coat
JFDLEHCO_03519 2.7e-137 spsF M Spore Coat
JFDLEHCO_03520 3.4e-216 spsE 2.5.1.56 M acid synthase
JFDLEHCO_03521 2.4e-161 spsD 2.3.1.210 K Spore Coat
JFDLEHCO_03522 5.1e-223 spsC E Belongs to the DegT DnrJ EryC1 family
JFDLEHCO_03523 1.2e-277 spsB M Capsule polysaccharide biosynthesis protein
JFDLEHCO_03524 2.6e-143 spsA M Spore Coat
JFDLEHCO_03525 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
JFDLEHCO_03526 1.4e-46 ywdK S small membrane protein
JFDLEHCO_03527 5.2e-232 ywdJ F Xanthine uracil
JFDLEHCO_03528 7.3e-41 ywdI S Family of unknown function (DUF5327)
JFDLEHCO_03529 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JFDLEHCO_03530 5.4e-155 ywdF GT2,GT4 S Glycosyltransferase like family 2
JFDLEHCO_03532 5.3e-89 ywdD
JFDLEHCO_03533 6.3e-57 pex K Transcriptional regulator PadR-like family
JFDLEHCO_03534 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JFDLEHCO_03535 9.7e-20 ywdA
JFDLEHCO_03536 1.2e-290 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
JFDLEHCO_03537 3.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JFDLEHCO_03538 1.3e-151 sacT K transcriptional antiterminator
JFDLEHCO_03540 0.0 vpr O Belongs to the peptidase S8 family
JFDLEHCO_03541 3.9e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JFDLEHCO_03542 2.2e-54 L COG2963 Transposase and inactivated derivatives
JFDLEHCO_03543 9.5e-135 L Molecular Function DNA binding, Biological Process DNA recombination
JFDLEHCO_03544 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
JFDLEHCO_03545 9.8e-214 rodA D Belongs to the SEDS family
JFDLEHCO_03546 1e-82 ysnE K acetyltransferase
JFDLEHCO_03547 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
JFDLEHCO_03548 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
JFDLEHCO_03549 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
JFDLEHCO_03550 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JFDLEHCO_03551 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
JFDLEHCO_03552 8.4e-27 ywzA S membrane
JFDLEHCO_03553 4.3e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JFDLEHCO_03554 5.7e-230 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JFDLEHCO_03555 1.9e-63 gtcA S GtrA-like protein
JFDLEHCO_03556 8.7e-113 ywcC K Bacterial regulatory proteins, tetR family
JFDLEHCO_03558 1.9e-129 H Methionine biosynthesis protein MetW
JFDLEHCO_03559 2.6e-134 S Streptomycin biosynthesis protein StrF
JFDLEHCO_03560 5.5e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
JFDLEHCO_03561 1.1e-244 ywbN P Dyp-type peroxidase family protein
JFDLEHCO_03562 9.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
JFDLEHCO_03563 6e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JFDLEHCO_03564 8.2e-152 ywbI K Transcriptional regulator
JFDLEHCO_03565 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
JFDLEHCO_03566 1.5e-110 ywbG M effector of murein hydrolase
JFDLEHCO_03567 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
JFDLEHCO_03568 2.2e-142 mta K transcriptional
JFDLEHCO_03569 1.2e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
JFDLEHCO_03570 5.5e-225 ywbD 2.1.1.191 J Methyltransferase
JFDLEHCO_03571 9e-68 ywbC 4.4.1.5 E glyoxalase
JFDLEHCO_03572 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JFDLEHCO_03573 7e-269 epr 3.4.21.62 O Belongs to the peptidase S8 family
JFDLEHCO_03574 5.2e-164 gspA M General stress
JFDLEHCO_03575 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
JFDLEHCO_03576 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
JFDLEHCO_03577 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
JFDLEHCO_03578 4.2e-294 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_03579 3.7e-229 dltB M membrane protein involved in D-alanine export
JFDLEHCO_03580 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JFDLEHCO_03581 3.7e-229 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JFDLEHCO_03582 4e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JFDLEHCO_03583 9.2e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
JFDLEHCO_03584 7.8e-52 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
JFDLEHCO_03585 2.6e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JFDLEHCO_03586 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
JFDLEHCO_03587 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
JFDLEHCO_03588 1.1e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
JFDLEHCO_03589 4.3e-173 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFDLEHCO_03590 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JFDLEHCO_03591 3e-167 cbrA3 P Periplasmic binding protein
JFDLEHCO_03592 3.7e-60 arsR K transcriptional
JFDLEHCO_03593 1.4e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JFDLEHCO_03594 6.9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
JFDLEHCO_03595 1.4e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
JFDLEHCO_03596 3.7e-230 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JFDLEHCO_03597 7.1e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JFDLEHCO_03598 4.2e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
JFDLEHCO_03599 8.4e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
JFDLEHCO_03600 4.4e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
JFDLEHCO_03601 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
JFDLEHCO_03602 6.5e-195 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
JFDLEHCO_03603 4.2e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
JFDLEHCO_03604 7e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JFDLEHCO_03605 2.2e-294 cydD V ATP-binding protein
JFDLEHCO_03606 0.0 cydD V ATP-binding
JFDLEHCO_03607 4.2e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
JFDLEHCO_03608 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
JFDLEHCO_03609 1.5e-215 cimH C COG3493 Na citrate symporter
JFDLEHCO_03610 7.1e-158 yxkH G Polysaccharide deacetylase
JFDLEHCO_03611 2.4e-206 msmK P Belongs to the ABC transporter superfamily
JFDLEHCO_03612 6.5e-170 lrp QT PucR C-terminal helix-turn-helix domain
JFDLEHCO_03613 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JFDLEHCO_03614 3.8e-87 yxkC S Domain of unknown function (DUF4352)
JFDLEHCO_03615 2.1e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JFDLEHCO_03616 6.5e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JFDLEHCO_03619 1.8e-86 yxjI S LURP-one-related
JFDLEHCO_03620 1.5e-219 yxjG 2.1.1.14 E Methionine synthase
JFDLEHCO_03621 5.6e-166 rlmA 2.1.1.187 Q Methyltransferase domain
JFDLEHCO_03622 3.5e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JFDLEHCO_03623 2.7e-75 T Domain of unknown function (DUF4163)
JFDLEHCO_03624 1.6e-51 yxiS
JFDLEHCO_03625 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
JFDLEHCO_03626 5.6e-223 citH C Citrate transporter
JFDLEHCO_03627 5e-144 exoK GH16 M licheninase activity
JFDLEHCO_03628 1.8e-150 licT K transcriptional antiterminator
JFDLEHCO_03629 2.9e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
JFDLEHCO_03630 1.6e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
JFDLEHCO_03633 2.9e-63 S SMI1-KNR4 cell-wall
JFDLEHCO_03634 9.1e-91 yxiI S Protein of unknown function (DUF2716)
JFDLEHCO_03636 3.1e-74 yxiG
JFDLEHCO_03637 7.1e-71 yxxG
JFDLEHCO_03639 3.7e-204 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
JFDLEHCO_03640 3.2e-148 yxxF EG EamA-like transporter family
JFDLEHCO_03641 9.8e-74 yxiE T Belongs to the universal stress protein A family
JFDLEHCO_03642 6.4e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JFDLEHCO_03643 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JFDLEHCO_03644 0.0 L HKD family nuclease
JFDLEHCO_03645 6.5e-66 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
JFDLEHCO_03646 1.5e-282 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
JFDLEHCO_03647 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
JFDLEHCO_03648 3.5e-288 hutH 4.3.1.3 E Histidine ammonia-lyase
JFDLEHCO_03649 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JFDLEHCO_03650 6.5e-240 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
JFDLEHCO_03651 3.1e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
JFDLEHCO_03652 2e-253 lysP E amino acid
JFDLEHCO_03653 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
JFDLEHCO_03654 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JFDLEHCO_03655 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JFDLEHCO_03656 2.3e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
JFDLEHCO_03657 6.2e-151 yidA S hydrolases of the HAD superfamily
JFDLEHCO_03660 6.4e-13 yxeE
JFDLEHCO_03661 8.4e-23 yxeD
JFDLEHCO_03662 1.3e-14
JFDLEHCO_03663 7.5e-11
JFDLEHCO_03664 4.4e-180 fhuD P Periplasmic binding protein
JFDLEHCO_03665 2.2e-54 L COG2963 Transposase and inactivated derivatives
JFDLEHCO_03666 7.3e-135 L Molecular Function DNA binding, Biological Process DNA recombination
JFDLEHCO_03667 2.6e-58 yxeA S Protein of unknown function (DUF1093)
JFDLEHCO_03668 0.0 yxdM V ABC transporter (permease)
JFDLEHCO_03669 5.5e-141 yxdL V ABC transporter, ATP-binding protein
JFDLEHCO_03670 1e-176 T PhoQ Sensor
JFDLEHCO_03671 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JFDLEHCO_03672 8.4e-276 T Histidine kinase
JFDLEHCO_03673 2.4e-138 T Transcriptional regulator
JFDLEHCO_03674 1.4e-164 bcrA V ABC transporter, ATP-binding protein
JFDLEHCO_03675 1e-131 S permease
JFDLEHCO_03676 9.3e-130 S ABC-2 family transporter protein
JFDLEHCO_03677 4.9e-162 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
JFDLEHCO_03678 1.3e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
JFDLEHCO_03679 1.1e-166 iolH G Xylose isomerase-like TIM barrel
JFDLEHCO_03680 3.3e-197 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
JFDLEHCO_03681 2.4e-234 iolF EGP Major facilitator Superfamily
JFDLEHCO_03682 1e-178 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
JFDLEHCO_03683 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
JFDLEHCO_03684 6.8e-184 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
JFDLEHCO_03685 1.5e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
JFDLEHCO_03686 1.2e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JFDLEHCO_03687 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
JFDLEHCO_03688 4.9e-176 iolS C Aldo keto reductase
JFDLEHCO_03689 6.7e-246 csbC EGP Major facilitator Superfamily
JFDLEHCO_03690 0.0 htpG O Molecular chaperone. Has ATPase activity
JFDLEHCO_03691 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
JFDLEHCO_03692 2.5e-104 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JFDLEHCO_03693 1.7e-202 desK 2.7.13.3 T Histidine kinase
JFDLEHCO_03694 3.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
JFDLEHCO_03695 4.3e-222 yxbF K Bacterial regulatory proteins, tetR family
JFDLEHCO_03696 3.9e-251 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
JFDLEHCO_03697 3.3e-143 S PQQ-like domain
JFDLEHCO_03698 4.1e-66 S Family of unknown function (DUF5391)
JFDLEHCO_03699 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
JFDLEHCO_03700 6.7e-207 EGP Major facilitator Superfamily
JFDLEHCO_03701 5.3e-75 yxaI S membrane protein domain
JFDLEHCO_03702 5.1e-130 E Ring-cleavage extradiol dioxygenase
JFDLEHCO_03703 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
JFDLEHCO_03704 2.3e-287 ahpF O Alkyl hydroperoxide reductase
JFDLEHCO_03705 5.4e-231 XK27_00240 S Fic/DOC family
JFDLEHCO_03706 6.5e-246 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
JFDLEHCO_03707 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
JFDLEHCO_03708 3e-86 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
JFDLEHCO_03709 5.8e-160 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
JFDLEHCO_03710 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
JFDLEHCO_03711 2.3e-97 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
JFDLEHCO_03712 1.3e-193 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JFDLEHCO_03713 1.3e-185 S Fusaric acid resistance protein-like
JFDLEHCO_03717 9.4e-286 L ATPase involved in DNA repair
JFDLEHCO_03718 2.8e-08
JFDLEHCO_03719 4.6e-238 T Putative serine esterase (DUF676)
JFDLEHCO_03720 9.8e-190
JFDLEHCO_03721 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JFDLEHCO_03722 7.9e-08 S YyzF-like protein
JFDLEHCO_03724 3.5e-224 yycP
JFDLEHCO_03725 1.7e-134 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JFDLEHCO_03726 1.4e-186 C oxidoreductases (related to aryl-alcohol dehydrogenases)
JFDLEHCO_03727 1.5e-88 yycN 2.3.1.128 K Acetyltransferase
JFDLEHCO_03729 8.6e-204 S Histidine kinase
JFDLEHCO_03730 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
JFDLEHCO_03731 6.9e-259 rocE E amino acid
JFDLEHCO_03732 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
JFDLEHCO_03733 3.4e-261 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
JFDLEHCO_03734 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
JFDLEHCO_03735 7.9e-307 S ABC transporter
JFDLEHCO_03736 2.6e-198 S Major Facilitator Superfamily
JFDLEHCO_03737 4.7e-265
JFDLEHCO_03738 2.5e-194 2.7.7.73, 2.7.7.80 H ThiF family
JFDLEHCO_03739 1.8e-259 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
JFDLEHCO_03740 3.2e-11 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JFDLEHCO_03741 8.3e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JFDLEHCO_03742 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
JFDLEHCO_03743 8.9e-153 yycI S protein conserved in bacteria
JFDLEHCO_03744 2.5e-261 yycH S protein conserved in bacteria
JFDLEHCO_03745 0.0 vicK 2.7.13.3 T Histidine kinase
JFDLEHCO_03746 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JFDLEHCO_03751 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JFDLEHCO_03752 4.8e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JFDLEHCO_03753 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JFDLEHCO_03754 1.6e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
JFDLEHCO_03756 3.5e-17 yycC K YycC-like protein
JFDLEHCO_03757 2.9e-41 M 4-amino-4-deoxy-L-arabinose transferase activity
JFDLEHCO_03758 3e-248 M Glycosyltransferase Family 4
JFDLEHCO_03759 3.5e-207 S Ecdysteroid kinase
JFDLEHCO_03760 7.5e-238 S Carbamoyl-phosphate synthase L chain, ATP binding domain
JFDLEHCO_03761 5.4e-253 M Glycosyltransferase Family 4
JFDLEHCO_03762 9.8e-123 S GlcNAc-PI de-N-acetylase
JFDLEHCO_03763 1.8e-127 KLT COG0515 Serine threonine protein kinase
JFDLEHCO_03764 4.9e-73 rplI J binds to the 23S rRNA
JFDLEHCO_03765 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JFDLEHCO_03766 2.9e-160 yybS S membrane
JFDLEHCO_03768 6e-85 cotF M Spore coat protein
JFDLEHCO_03769 2.8e-66 ydeP3 K Transcriptional regulator
JFDLEHCO_03770 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
JFDLEHCO_03771 1.4e-156 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JFDLEHCO_03772 7e-275 sacB 2.4.1.10 GH68 M levansucrase activity
JFDLEHCO_03773 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
JFDLEHCO_03774 4.8e-117 K FCD domain
JFDLEHCO_03775 1.3e-77 dinB S PFAM DinB family protein
JFDLEHCO_03776 1.2e-163 G Major Facilitator Superfamily
JFDLEHCO_03777 1.7e-17 G Major Facilitator Superfamily
JFDLEHCO_03778 3.4e-163 yfiE K LysR substrate binding domain
JFDLEHCO_03779 1.1e-100 E LysE type translocator
JFDLEHCO_03780 3e-218 ynfM EGP Major facilitator Superfamily
JFDLEHCO_03781 3.3e-166 gltC K Transcriptional regulator
JFDLEHCO_03782 3.4e-56 ypaA S Protein of unknown function (DUF1304)
JFDLEHCO_03783 5.6e-115 drgA C nitroreductase
JFDLEHCO_03784 1.1e-69 ydgJ K Winged helix DNA-binding domain
JFDLEHCO_03785 3.8e-154 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
JFDLEHCO_03786 2.5e-77 yybA 2.3.1.57 K transcriptional
JFDLEHCO_03787 1.8e-77 yjcF S Acetyltransferase (GNAT) domain
JFDLEHCO_03788 2.3e-164 eaeH M Domain of Unknown Function (DUF1259)
JFDLEHCO_03789 9.4e-68 4.1.1.44 S Carboxymuconolactone decarboxylase family
JFDLEHCO_03790 4.5e-166 K Transcriptional regulator
JFDLEHCO_03791 3.6e-143 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
JFDLEHCO_03792 4.4e-100
JFDLEHCO_03793 1.5e-27 yyaL O Highly conserved protein containing a thioredoxin domain
JFDLEHCO_03794 4e-81
JFDLEHCO_03795 1.3e-69 ynaF
JFDLEHCO_03797 1.1e-250 KLT Protein tyrosine kinase
JFDLEHCO_03798 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
JFDLEHCO_03799 1.3e-165 yyaK S CAAX protease self-immunity
JFDLEHCO_03800 2.1e-249 ydjK G Sugar (and other) transporter
JFDLEHCO_03801 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JFDLEHCO_03802 4.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
JFDLEHCO_03803 5.1e-147 xth 3.1.11.2 L exodeoxyribonuclease III
JFDLEHCO_03804 4.3e-103 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JFDLEHCO_03805 4.9e-110 adaA 3.2.2.21 K Transcriptional regulator
JFDLEHCO_03806 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JFDLEHCO_03807 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JFDLEHCO_03808 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
JFDLEHCO_03809 1.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JFDLEHCO_03810 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JFDLEHCO_03811 7.8e-34 yyzM S protein conserved in bacteria
JFDLEHCO_03812 2.4e-176 yyaD S Membrane
JFDLEHCO_03813 1.8e-87 4.2.1.103 K FR47-like protein
JFDLEHCO_03814 6.2e-111 yyaC S Sporulation protein YyaC
JFDLEHCO_03815 1.6e-149 spo0J K Belongs to the ParB family
JFDLEHCO_03816 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
JFDLEHCO_03817 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
JFDLEHCO_03818 1.3e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
JFDLEHCO_03819 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JFDLEHCO_03820 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JFDLEHCO_03821 4.5e-112 jag S single-stranded nucleic acid binding R3H
JFDLEHCO_03822 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JFDLEHCO_03823 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)