ORF_ID e_value Gene_name EC_number CAZy COGs Description
JHMANCOO_00001 8.3e-102 K Helix-turn-helix domain
JHMANCOO_00002 0.0 tetP J elongation factor G
JHMANCOO_00003 4.8e-151 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
JHMANCOO_00004 6.2e-193 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHMANCOO_00007 2.5e-155 xth 3.1.11.2 L exodeoxyribonuclease III
JHMANCOO_00008 1.3e-273 E amino acid
JHMANCOO_00009 0.0 L Helicase C-terminal domain protein
JHMANCOO_00010 6.2e-205 pbpX1 V Beta-lactamase
JHMANCOO_00011 4.6e-227 N Uncharacterized conserved protein (DUF2075)
JHMANCOO_00012 1.2e-70 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
JHMANCOO_00031 2.1e-14 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
JHMANCOO_00032 2.4e-13 S HIRAN domain
JHMANCOO_00033 7.9e-117 KL domain protein
JHMANCOO_00034 9.8e-33 S DNA primase
JHMANCOO_00035 3.4e-49
JHMANCOO_00036 2.9e-21
JHMANCOO_00037 2.2e-53
JHMANCOO_00038 1.2e-13 S Helix-turn-helix domain
JHMANCOO_00039 1.3e-48 3.1.21.3 V Type I restriction modification DNA specificity domain
JHMANCOO_00040 1.1e-146 L Belongs to the 'phage' integrase family
JHMANCOO_00042 3.6e-108 3.2.1.99 GH43 M C-terminal of Glycosyl hydrolases family 43
JHMANCOO_00043 1.4e-65 pssE S Glycosyltransferase family 28 C-terminal domain
JHMANCOO_00044 8.3e-81 cpsF M Oligosaccharide biosynthesis protein Alg14 like
JHMANCOO_00045 4.6e-44 M Glycosyltransferase
JHMANCOO_00046 2.4e-123 6.2.1.3 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
JHMANCOO_00056 1.2e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
JHMANCOO_00057 2.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
JHMANCOO_00058 2e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JHMANCOO_00059 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
JHMANCOO_00060 1.7e-29 secG U Preprotein translocase
JHMANCOO_00061 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JHMANCOO_00062 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
JHMANCOO_00063 1.8e-96 S ABC-type cobalt transport system, permease component
JHMANCOO_00066 8.7e-187 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
JHMANCOO_00067 1.1e-128 manY G PTS system
JHMANCOO_00068 1e-173 manN G system, mannose fructose sorbose family IID component
JHMANCOO_00069 3.8e-63 manO S Domain of unknown function (DUF956)
JHMANCOO_00070 5.7e-158 K Transcriptional regulator
JHMANCOO_00071 8.7e-32 maa S transferase hexapeptide repeat
JHMANCOO_00072 4.1e-38 maa S transferase hexapeptide repeat
JHMANCOO_00073 1.1e-243 cycA E Amino acid permease
JHMANCOO_00074 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JHMANCOO_00075 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JHMANCOO_00076 0.0 mtlR K Mga helix-turn-helix domain
JHMANCOO_00077 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
JHMANCOO_00078 7.1e-80 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHMANCOO_00079 1.3e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
JHMANCOO_00080 1.3e-136 4.1.1.44 S Carboxymuconolactone decarboxylase family
JHMANCOO_00081 1.6e-32
JHMANCOO_00082 6.7e-69 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
JHMANCOO_00083 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
JHMANCOO_00084 0.0 S TerB-C domain
JHMANCOO_00085 5.4e-253 P P-loop Domain of unknown function (DUF2791)
JHMANCOO_00086 0.0 lhr L DEAD DEAH box helicase
JHMANCOO_00087 1.9e-59
JHMANCOO_00088 1.4e-142 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
JHMANCOO_00090 1e-61 psiE S Phosphate-starvation-inducible E
JHMANCOO_00091 3.8e-113 yncA 2.3.1.79 S Maltose acetyltransferase
JHMANCOO_00092 1.5e-70 S Iron-sulphur cluster biosynthesis
JHMANCOO_00094 4.6e-31
JHMANCOO_00095 1.1e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
JHMANCOO_00096 6.2e-12
JHMANCOO_00097 1.6e-98 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHMANCOO_00098 3.4e-78 M LysM domain protein
JHMANCOO_00099 1.5e-160 D nuclear chromosome segregation
JHMANCOO_00100 1.2e-105 G Phosphoglycerate mutase family
JHMANCOO_00101 3.1e-99 G Histidine phosphatase superfamily (branch 1)
JHMANCOO_00102 9.9e-115 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
JHMANCOO_00103 2.1e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JHMANCOO_00105 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
JHMANCOO_00106 1.2e-211 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
JHMANCOO_00107 1.8e-184 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
JHMANCOO_00108 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
JHMANCOO_00109 4.4e-144 K SIS domain
JHMANCOO_00110 2.3e-228 slpX S SLAP domain
JHMANCOO_00111 1.3e-22 3.6.4.12 S transposase or invertase
JHMANCOO_00112 7.7e-12
JHMANCOO_00113 1.1e-240 npr 1.11.1.1 C NADH oxidase
JHMANCOO_00116 1.5e-64
JHMANCOO_00120 1.8e-220 sip L Belongs to the 'phage' integrase family
JHMANCOO_00121 4.6e-299 oppA2 E ABC transporter, substratebinding protein
JHMANCOO_00122 1.1e-179
JHMANCOO_00123 1.3e-125 gntR1 K UTRA
JHMANCOO_00124 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
JHMANCOO_00125 4.3e-135 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
JHMANCOO_00126 9e-206 csaB M Glycosyl transferases group 1
JHMANCOO_00127 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JHMANCOO_00128 4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JHMANCOO_00129 0.0 pacL 3.6.3.8 P P-type ATPase
JHMANCOO_00130 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
JHMANCOO_00131 9.2e-259 epsU S Polysaccharide biosynthesis protein
JHMANCOO_00132 9.1e-135 M Glycosyltransferase sugar-binding region containing DXD motif
JHMANCOO_00133 2.8e-84 ydcK S Belongs to the SprT family
JHMANCOO_00135 2.5e-86 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
JHMANCOO_00136 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JHMANCOO_00137 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JHMANCOO_00138 5.4e-201 camS S sex pheromone
JHMANCOO_00139 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JHMANCOO_00140 7.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JHMANCOO_00141 4.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JHMANCOO_00142 7.2e-172 yegS 2.7.1.107 G Lipid kinase
JHMANCOO_00143 4.3e-108 ybhL S Belongs to the BI1 family
JHMANCOO_00144 2.6e-57
JHMANCOO_00145 4.2e-95 VPA0052 I transferase activity, transferring acyl groups other than amino-acyl groups
JHMANCOO_00146 6e-231 nhaC C Na H antiporter NhaC
JHMANCOO_00147 7.8e-199 pbpX V Beta-lactamase
JHMANCOO_00148 2.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JHMANCOO_00149 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
JHMANCOO_00154 1.1e-259 emrY EGP Major facilitator Superfamily
JHMANCOO_00155 2e-91 yxdD K Bacterial regulatory proteins, tetR family
JHMANCOO_00156 0.0 4.2.1.53 S Myosin-crossreactive antigen
JHMANCOO_00157 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
JHMANCOO_00158 8.3e-95 K Helix-turn-helix XRE-family like proteins
JHMANCOO_00159 2.7e-206 V ABC transporter transmembrane region
JHMANCOO_00161 2.7e-14
JHMANCOO_00162 1.8e-158 S reductase
JHMANCOO_00163 9.3e-35
JHMANCOO_00164 6.3e-290 K Putative DNA-binding domain
JHMANCOO_00165 2.4e-232 pyrP F Permease
JHMANCOO_00166 3.8e-85 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JHMANCOO_00167 3.8e-260 emrY EGP Major facilitator Superfamily
JHMANCOO_00168 1.1e-217 mdtG EGP Major facilitator Superfamily
JHMANCOO_00169 3.7e-137
JHMANCOO_00170 1.4e-104
JHMANCOO_00171 2.3e-209 pepA E M42 glutamyl aminopeptidase
JHMANCOO_00172 9.9e-310 ybiT S ABC transporter, ATP-binding protein
JHMANCOO_00173 5.9e-174 S Aldo keto reductase
JHMANCOO_00174 1.8e-150
JHMANCOO_00175 2.8e-241 steT E amino acid
JHMANCOO_00176 3e-243 steT E amino acid
JHMANCOO_00177 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
JHMANCOO_00178 6.4e-148 glnH ET ABC transporter
JHMANCOO_00179 1.4e-80 K Transcriptional regulator, MarR family
JHMANCOO_00180 1.8e-309 XK27_09600 V ABC transporter, ATP-binding protein
JHMANCOO_00181 0.0 V ABC transporter transmembrane region
JHMANCOO_00182 3.8e-102 S ABC-type cobalt transport system, permease component
JHMANCOO_00183 1.1e-229 G MFS/sugar transport protein
JHMANCOO_00184 1.5e-112 udk 2.7.1.48 F Zeta toxin
JHMANCOO_00185 1.9e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JHMANCOO_00186 2.4e-150 glnH ET ABC transporter substrate-binding protein
JHMANCOO_00187 9.7e-91 gluC P ABC transporter permease
JHMANCOO_00188 4.7e-109 glnP P ABC transporter permease
JHMANCOO_00189 7.2e-164 S Protein of unknown function (DUF2974)
JHMANCOO_00190 5.6e-86
JHMANCOO_00191 1.1e-211 S Uncharacterized protein conserved in bacteria (DUF2325)
JHMANCOO_00192 5.9e-236 G Bacterial extracellular solute-binding protein
JHMANCOO_00193 2.2e-161 2.7.7.12 C Domain of unknown function (DUF4931)
JHMANCOO_00194 1.3e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHMANCOO_00195 1.7e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JHMANCOO_00196 0.0 kup P Transport of potassium into the cell
JHMANCOO_00197 1.6e-174 rihB 3.2.2.1 F Nucleoside
JHMANCOO_00198 3.4e-132 ydhQ K UbiC transcription regulator-associated domain protein
JHMANCOO_00199 7.9e-154 S hydrolase
JHMANCOO_00200 1e-60 S Enterocin A Immunity
JHMANCOO_00201 9.6e-138 glcR K DeoR C terminal sensor domain
JHMANCOO_00202 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
JHMANCOO_00203 7.4e-155 rssA S Phospholipase, patatin family
JHMANCOO_00204 2.3e-20 S hydrolase
JHMANCOO_00205 1e-110 S hydrolase
JHMANCOO_00206 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
JHMANCOO_00207 5.4e-147 glvR K Helix-turn-helix domain, rpiR family
JHMANCOO_00208 6e-80
JHMANCOO_00209 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
JHMANCOO_00210 2.1e-39
JHMANCOO_00211 2.3e-119 C nitroreductase
JHMANCOO_00212 2.2e-249 yhdP S Transporter associated domain
JHMANCOO_00213 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JHMANCOO_00214 0.0 1.3.5.4 C FAD binding domain
JHMANCOO_00215 5.9e-89 L PFAM transposase, IS4 family protein
JHMANCOO_00216 0.0 1.3.5.4 C FAD binding domain
JHMANCOO_00217 1.1e-229 potE E amino acid
JHMANCOO_00218 4.7e-131 M Glycosyl hydrolases family 25
JHMANCOO_00219 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
JHMANCOO_00220 1.2e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHMANCOO_00222 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JHMANCOO_00223 3.1e-87 gtcA S Teichoic acid glycosylation protein
JHMANCOO_00224 4.1e-80 fld C Flavodoxin
JHMANCOO_00225 6.5e-164 map 3.4.11.18 E Methionine Aminopeptidase
JHMANCOO_00226 3.6e-163 yihY S Belongs to the UPF0761 family
JHMANCOO_00227 7.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JHMANCOO_00228 2.3e-215 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
JHMANCOO_00229 4.5e-214 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
JHMANCOO_00230 1.6e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
JHMANCOO_00231 9.4e-46
JHMANCOO_00232 6.7e-178 D Alpha beta
JHMANCOO_00233 3e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JHMANCOO_00234 8.6e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
JHMANCOO_00235 1.6e-85
JHMANCOO_00236 1.6e-74
JHMANCOO_00237 1.1e-140 hlyX S Transporter associated domain
JHMANCOO_00238 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JHMANCOO_00239 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
JHMANCOO_00240 0.0 clpE O Belongs to the ClpA ClpB family
JHMANCOO_00241 5.3e-26
JHMANCOO_00242 8.5e-41 ptsH G phosphocarrier protein HPR
JHMANCOO_00243 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JHMANCOO_00244 6.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JHMANCOO_00245 7.2e-138 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
JHMANCOO_00246 5.8e-160 coiA 3.6.4.12 S Competence protein
JHMANCOO_00247 1.2e-114 yjbH Q Thioredoxin
JHMANCOO_00248 3.6e-111 yjbK S CYTH
JHMANCOO_00249 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
JHMANCOO_00250 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JHMANCOO_00251 5.4e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JHMANCOO_00252 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
JHMANCOO_00253 3.2e-92 S SNARE associated Golgi protein
JHMANCOO_00254 1.1e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
JHMANCOO_00255 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
JHMANCOO_00256 4.9e-213 yubA S AI-2E family transporter
JHMANCOO_00257 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JHMANCOO_00258 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
JHMANCOO_00259 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JHMANCOO_00260 2.6e-222 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
JHMANCOO_00261 1.6e-235 S Peptidase M16
JHMANCOO_00262 1.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
JHMANCOO_00263 6.8e-97 ymfM S Helix-turn-helix domain
JHMANCOO_00264 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JHMANCOO_00265 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JHMANCOO_00266 1.1e-218 rny S Endoribonuclease that initiates mRNA decay
JHMANCOO_00267 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
JHMANCOO_00268 1.6e-117 yvyE 3.4.13.9 S YigZ family
JHMANCOO_00269 1.6e-246 comFA L Helicase C-terminal domain protein
JHMANCOO_00270 1.1e-135 comFC S Competence protein
JHMANCOO_00271 4.2e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JHMANCOO_00272 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JHMANCOO_00273 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JHMANCOO_00274 5.1e-17
JHMANCOO_00275 9.2e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JHMANCOO_00276 1.2e-152 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JHMANCOO_00277 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JHMANCOO_00278 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JHMANCOO_00279 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
JHMANCOO_00280 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JHMANCOO_00281 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
JHMANCOO_00282 1.1e-90 S Short repeat of unknown function (DUF308)
JHMANCOO_00283 6.2e-165 rapZ S Displays ATPase and GTPase activities
JHMANCOO_00284 1.1e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JHMANCOO_00285 2.1e-171 whiA K May be required for sporulation
JHMANCOO_00286 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JHMANCOO_00287 0.0 S SH3-like domain
JHMANCOO_00288 4.9e-111 ybbL S ABC transporter, ATP-binding protein
JHMANCOO_00289 3.3e-130 ybbM S Uncharacterised protein family (UPF0014)
JHMANCOO_00290 2.8e-94 S Domain of unknown function (DUF4811)
JHMANCOO_00291 3.9e-260 lmrB EGP Major facilitator Superfamily
JHMANCOO_00292 5.4e-77 K MerR HTH family regulatory protein
JHMANCOO_00293 1e-142 S Cysteine-rich secretory protein family
JHMANCOO_00294 6e-274 ycaM E amino acid
JHMANCOO_00295 1.2e-288
JHMANCOO_00297 9.5e-189 cggR K Putative sugar-binding domain
JHMANCOO_00298 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JHMANCOO_00299 1.8e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JHMANCOO_00300 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JHMANCOO_00301 1.2e-94
JHMANCOO_00302 1.4e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
JHMANCOO_00303 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JHMANCOO_00304 6.3e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
JHMANCOO_00305 1.4e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
JHMANCOO_00306 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
JHMANCOO_00307 1.8e-164 murB 1.3.1.98 M Cell wall formation
JHMANCOO_00308 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JHMANCOO_00309 5.4e-131 potB P ABC transporter permease
JHMANCOO_00310 2.1e-127 potC P ABC transporter permease
JHMANCOO_00311 4.7e-207 potD P ABC transporter
JHMANCOO_00312 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JHMANCOO_00313 2e-172 ybbR S YbbR-like protein
JHMANCOO_00314 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHMANCOO_00315 2.4e-147 S hydrolase
JHMANCOO_00316 6e-76 K Penicillinase repressor
JHMANCOO_00317 2.5e-119
JHMANCOO_00318 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JHMANCOO_00319 1.3e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JHMANCOO_00320 1.7e-143 licT K CAT RNA binding domain
JHMANCOO_00321 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
JHMANCOO_00322 3.8e-300 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHMANCOO_00323 6.5e-176 D Alpha beta
JHMANCOO_00324 1.7e-304 E Amino acid permease
JHMANCOO_00326 2.7e-25 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JHMANCOO_00327 2e-94 S VanZ like family
JHMANCOO_00328 8.9e-133 yebC K Transcriptional regulatory protein
JHMANCOO_00329 1.4e-178 comGA NU Type II IV secretion system protein
JHMANCOO_00330 1.5e-170 comGB NU type II secretion system
JHMANCOO_00331 3.1e-43 comGC U competence protein ComGC
JHMANCOO_00332 7.4e-71
JHMANCOO_00333 2.3e-41
JHMANCOO_00334 3.8e-77 comGF U Putative Competence protein ComGF
JHMANCOO_00335 1.6e-21
JHMANCOO_00336 3.5e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
JHMANCOO_00337 3.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHMANCOO_00339 9.1e-14
JHMANCOO_00341 1.6e-33
JHMANCOO_00345 2.6e-30
JHMANCOO_00346 2.6e-12 S Helix-turn-helix domain
JHMANCOO_00348 1.8e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
JHMANCOO_00349 1.4e-80 XK27_04435 3.5.4.5 J FR47-like protein
JHMANCOO_00350 1.4e-36 S Cytochrome B5
JHMANCOO_00351 1.3e-167 arbZ I Phosphate acyltransferases
JHMANCOO_00352 4.6e-182 arbY M Glycosyl transferase family 8
JHMANCOO_00353 4.5e-185 arbY M Glycosyl transferase family 8
JHMANCOO_00354 2.3e-156 arbx M Glycosyl transferase family 8
JHMANCOO_00355 1.4e-149 arbV 2.3.1.51 I Acyl-transferase
JHMANCOO_00357 4.9e-34
JHMANCOO_00359 4.8e-131 K response regulator
JHMANCOO_00360 1.4e-304 vicK 2.7.13.3 T Histidine kinase
JHMANCOO_00361 1.4e-245 yycH S YycH protein
JHMANCOO_00362 8.8e-145 yycI S YycH protein
JHMANCOO_00363 8.2e-148 vicX 3.1.26.11 S domain protein
JHMANCOO_00364 3.3e-151 htrA 3.4.21.107 O serine protease
JHMANCOO_00365 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JHMANCOO_00366 1.9e-103 G Peptidase_C39 like family
JHMANCOO_00367 6e-176 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
JHMANCOO_00368 2.1e-77 P Cobalt transport protein
JHMANCOO_00369 1.8e-248 cbiO1 S ABC transporter, ATP-binding protein
JHMANCOO_00370 7.9e-174 K helix_turn_helix, arabinose operon control protein
JHMANCOO_00371 5.8e-158 htpX O Belongs to the peptidase M48B family
JHMANCOO_00372 3.9e-96 lemA S LemA family
JHMANCOO_00373 4e-193 ybiR P Citrate transporter
JHMANCOO_00374 7.8e-70 S Iron-sulphur cluster biosynthesis
JHMANCOO_00375 8.4e-310 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
JHMANCOO_00376 1.2e-17
JHMANCOO_00377 3.1e-116
JHMANCOO_00379 5.2e-216 ydaM M Glycosyl transferase
JHMANCOO_00380 4.4e-176 G Glycosyl hydrolases family 8
JHMANCOO_00381 9.6e-35 yfbR S HD containing hydrolase-like enzyme
JHMANCOO_00382 7.6e-64 yfbR S HD containing hydrolase-like enzyme
JHMANCOO_00383 2.5e-155 L HNH nucleases
JHMANCOO_00384 1.2e-137 S Protein of unknown function (DUF805)
JHMANCOO_00385 8.9e-136 glnQ E ABC transporter, ATP-binding protein
JHMANCOO_00386 2.4e-284 glnP P ABC transporter permease
JHMANCOO_00387 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
JHMANCOO_00388 5.8e-64 yeaO S Protein of unknown function, DUF488
JHMANCOO_00389 9.6e-125 terC P Integral membrane protein TerC family
JHMANCOO_00390 3.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
JHMANCOO_00391 1.1e-132 cobB K SIR2 family
JHMANCOO_00392 4.2e-86
JHMANCOO_00393 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHMANCOO_00394 1.6e-182 S Alpha/beta hydrolase of unknown function (DUF915)
JHMANCOO_00395 8.8e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JHMANCOO_00396 4.4e-140 ypuA S Protein of unknown function (DUF1002)
JHMANCOO_00397 2.9e-156 epsV 2.7.8.12 S glycosyl transferase family 2
JHMANCOO_00398 7.3e-126 S Alpha/beta hydrolase family
JHMANCOO_00399 2.8e-80 K Helix-turn-helix domain
JHMANCOO_00400 9.1e-58 sip L Belongs to the 'phage' integrase family
JHMANCOO_00401 9.3e-66 sip L Belongs to the 'phage' integrase family
JHMANCOO_00402 3.4e-15 M Protein of unknown function (DUF3737)
JHMANCOO_00403 6.9e-79 M Protein of unknown function (DUF3737)
JHMANCOO_00404 1.1e-225 patB 4.4.1.8 E Aminotransferase, class I
JHMANCOO_00405 1.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
JHMANCOO_00406 1.3e-66 S SdpI/YhfL protein family
JHMANCOO_00407 4.4e-129 K Transcriptional regulatory protein, C terminal
JHMANCOO_00408 2.5e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
JHMANCOO_00409 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
JHMANCOO_00410 1.1e-104 vanZ V VanZ like family
JHMANCOO_00411 3.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
JHMANCOO_00412 7.6e-218 EGP Major facilitator Superfamily
JHMANCOO_00413 5.1e-195 ampC V Beta-lactamase
JHMANCOO_00416 2.5e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
JHMANCOO_00417 1.3e-113 tdk 2.7.1.21 F thymidine kinase
JHMANCOO_00418 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JHMANCOO_00419 2.5e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JHMANCOO_00420 2.9e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JHMANCOO_00421 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JHMANCOO_00422 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
JHMANCOO_00423 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JHMANCOO_00424 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JHMANCOO_00425 9.8e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JHMANCOO_00426 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JHMANCOO_00427 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JHMANCOO_00428 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JHMANCOO_00429 3.4e-71 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JHMANCOO_00430 4.1e-31 ywzB S Protein of unknown function (DUF1146)
JHMANCOO_00431 2.5e-178 mbl D Cell shape determining protein MreB Mrl
JHMANCOO_00432 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
JHMANCOO_00433 1.5e-33 S Protein of unknown function (DUF2969)
JHMANCOO_00434 1.2e-216 rodA D Belongs to the SEDS family
JHMANCOO_00435 7.1e-61
JHMANCOO_00436 1e-67
JHMANCOO_00437 7.8e-38 acfD M Membrane
JHMANCOO_00438 7.1e-144 S response to antibiotic
JHMANCOO_00439 1.5e-152
JHMANCOO_00440 2.4e-63 S zinc-ribbon domain
JHMANCOO_00441 2.3e-47 S zinc-ribbon domain
JHMANCOO_00442 9.8e-77 usp6 T universal stress protein
JHMANCOO_00443 2.4e-38
JHMANCOO_00444 8.2e-238 rarA L recombination factor protein RarA
JHMANCOO_00445 1.1e-83 yueI S Protein of unknown function (DUF1694)
JHMANCOO_00446 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JHMANCOO_00447 6.2e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JHMANCOO_00448 6.4e-213 iscS2 2.8.1.7 E Aminotransferase class V
JHMANCOO_00449 1.4e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHMANCOO_00450 6.7e-125 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JHMANCOO_00451 6.3e-25
JHMANCOO_00452 4.4e-135 K Helix-turn-helix XRE-family like proteins
JHMANCOO_00453 4.9e-99 S SLAP domain
JHMANCOO_00454 4.1e-150 K Helix-turn-helix XRE-family like proteins
JHMANCOO_00455 1.2e-94
JHMANCOO_00456 5.8e-260
JHMANCOO_00457 2.6e-195
JHMANCOO_00458 8.8e-293 S SLAP domain
JHMANCOO_00459 2.6e-106 S Protein of unknown function (DUF3232)
JHMANCOO_00460 2.1e-39 K Helix-turn-helix XRE-family like proteins
JHMANCOO_00461 2e-70
JHMANCOO_00462 4.7e-188
JHMANCOO_00463 2.7e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JHMANCOO_00464 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
JHMANCOO_00465 6.8e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
JHMANCOO_00466 1.5e-94 S Protein of unknown function (DUF3990)
JHMANCOO_00467 2.9e-44
JHMANCOO_00469 0.0 3.6.3.8 P P-type ATPase
JHMANCOO_00470 2.1e-171
JHMANCOO_00471 5.8e-106 K Helix-turn-helix domain
JHMANCOO_00472 5.9e-32 K Helix-turn-helix domain
JHMANCOO_00473 8.1e-14 1.3.5.4 C FAD binding domain
JHMANCOO_00474 2.2e-63 S Phage derived protein Gp49-like (DUF891)
JHMANCOO_00475 6e-42 K Helix-turn-helix XRE-family like proteins
JHMANCOO_00476 4.2e-68
JHMANCOO_00477 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JHMANCOO_00478 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JHMANCOO_00479 2e-126 S Haloacid dehalogenase-like hydrolase
JHMANCOO_00480 2.3e-108 radC L DNA repair protein
JHMANCOO_00481 2.4e-176 mreB D cell shape determining protein MreB
JHMANCOO_00482 6.7e-148 mreC M Involved in formation and maintenance of cell shape
JHMANCOO_00483 2.7e-94 mreD
JHMANCOO_00485 1.4e-53 S Protein of unknown function (DUF3397)
JHMANCOO_00486 1.9e-17
JHMANCOO_00487 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
JHMANCOO_00488 6.3e-78 mraZ K Belongs to the MraZ family
JHMANCOO_00489 1.1e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JHMANCOO_00490 4.1e-54 ftsL D Cell division protein FtsL
JHMANCOO_00491 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
JHMANCOO_00492 1.1e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JHMANCOO_00493 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JHMANCOO_00494 4.4e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JHMANCOO_00495 4.1e-153 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JHMANCOO_00496 7.7e-247 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JHMANCOO_00497 2.5e-205 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JHMANCOO_00498 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JHMANCOO_00499 6.5e-38 yggT S YGGT family
JHMANCOO_00500 2.6e-149 ylmH S S4 domain protein
JHMANCOO_00501 2.8e-74 gpsB D DivIVA domain protein
JHMANCOO_00502 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JHMANCOO_00503 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
JHMANCOO_00504 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
JHMANCOO_00505 2.1e-38
JHMANCOO_00506 3.5e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JHMANCOO_00507 1.2e-216 iscS 2.8.1.7 E Aminotransferase class V
JHMANCOO_00508 2.2e-57 XK27_04120 S Putative amino acid metabolism
JHMANCOO_00509 4.6e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JHMANCOO_00510 1.5e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
JHMANCOO_00511 8.3e-106 S Repeat protein
JHMANCOO_00512 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JHMANCOO_00513 2.2e-296 L Nuclease-related domain
JHMANCOO_00514 8e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
JHMANCOO_00515 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JHMANCOO_00516 9.3e-33 ykzG S Belongs to the UPF0356 family
JHMANCOO_00517 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JHMANCOO_00518 0.0 typA T GTP-binding protein TypA
JHMANCOO_00519 1.2e-211 ftsW D Belongs to the SEDS family
JHMANCOO_00520 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
JHMANCOO_00521 1.7e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
JHMANCOO_00522 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JHMANCOO_00523 3.3e-189 ylbL T Belongs to the peptidase S16 family
JHMANCOO_00524 6.1e-75 comEA L Competence protein ComEA
JHMANCOO_00525 0.0 comEC S Competence protein ComEC
JHMANCOO_00526 9.7e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
JHMANCOO_00527 6.7e-35 rpsT J Binds directly to 16S ribosomal RNA
JHMANCOO_00528 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JHMANCOO_00529 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JHMANCOO_00530 1.8e-150
JHMANCOO_00531 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JHMANCOO_00532 4e-216 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JHMANCOO_00533 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JHMANCOO_00534 3.7e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
JHMANCOO_00535 6e-39 yjeM E Amino Acid
JHMANCOO_00536 2.3e-121 yjeM E Amino Acid
JHMANCOO_00537 8.9e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JHMANCOO_00538 6.7e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
JHMANCOO_00539 8.2e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JHMANCOO_00540 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JHMANCOO_00541 1.5e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JHMANCOO_00542 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JHMANCOO_00543 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JHMANCOO_00544 1.3e-218 aspC 2.6.1.1 E Aminotransferase
JHMANCOO_00545 1.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JHMANCOO_00546 3.8e-196 pbpX1 V Beta-lactamase
JHMANCOO_00547 7.9e-299 I Protein of unknown function (DUF2974)
JHMANCOO_00548 3.6e-39 C FMN_bind
JHMANCOO_00549 1.9e-81
JHMANCOO_00550 4.8e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
JHMANCOO_00551 3.1e-53 alkD L DNA alkylation repair enzyme
JHMANCOO_00552 1.1e-30 alkD L DNA alkylation repair enzyme
JHMANCOO_00553 2.4e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHMANCOO_00554 1.6e-126 K UTRA domain
JHMANCOO_00555 1.6e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
JHMANCOO_00556 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
JHMANCOO_00557 7.4e-250 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHMANCOO_00558 3.2e-71 S Domain of unknown function (DUF3284)
JHMANCOO_00559 3.5e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHMANCOO_00560 3.8e-120 gmuR K UTRA
JHMANCOO_00561 1.7e-225 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHMANCOO_00562 2e-274 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JHMANCOO_00563 5.4e-137 ypbG 2.7.1.2 GK ROK family
JHMANCOO_00564 9.7e-83 C nitroreductase
JHMANCOO_00565 6.3e-90 S Domain of unknown function (DUF4767)
JHMANCOO_00566 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JHMANCOO_00567 1.3e-148 yitS S Uncharacterised protein, DegV family COG1307
JHMANCOO_00568 2.2e-102 3.6.1.27 I Acid phosphatase homologues
JHMANCOO_00570 1.7e-31 S ATP diphosphatase activity
JHMANCOO_00571 1.2e-214 EGP Major Facilitator Superfamily
JHMANCOO_00572 2.9e-139 noxC 1.5.1.39 C coenzyme F420-1:gamma-L-glutamate ligase activity
JHMANCOO_00573 2.6e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JHMANCOO_00574 1.4e-124 luxT K Bacterial regulatory proteins, tetR family
JHMANCOO_00575 2.8e-135
JHMANCOO_00576 1.3e-258 glnPH2 P ABC transporter permease
JHMANCOO_00577 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JHMANCOO_00578 1e-221 S Cysteine-rich secretory protein family
JHMANCOO_00579 1.3e-204 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JHMANCOO_00580 1.9e-109
JHMANCOO_00581 1.4e-201 yibE S overlaps another CDS with the same product name
JHMANCOO_00582 1.7e-129 yibF S overlaps another CDS with the same product name
JHMANCOO_00583 2.1e-146 I alpha/beta hydrolase fold
JHMANCOO_00584 0.0 G Belongs to the glycosyl hydrolase 31 family
JHMANCOO_00585 2.1e-216 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JHMANCOO_00586 3.2e-10
JHMANCOO_00587 5.6e-08
JHMANCOO_00588 1.1e-22 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
JHMANCOO_00589 3.6e-90 ntd 2.4.2.6 F Nucleoside
JHMANCOO_00590 3.9e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JHMANCOO_00591 1.7e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
JHMANCOO_00592 1.5e-83 uspA T universal stress protein
JHMANCOO_00593 4.1e-151 phnD P Phosphonate ABC transporter
JHMANCOO_00594 4.1e-136 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JHMANCOO_00595 2.3e-118 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
JHMANCOO_00596 2.2e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
JHMANCOO_00597 3.6e-105 tag 3.2.2.20 L glycosylase
JHMANCOO_00598 1.5e-83
JHMANCOO_00599 1.5e-274 S Calcineurin-like phosphoesterase
JHMANCOO_00600 0.0 asnB 6.3.5.4 E Asparagine synthase
JHMANCOO_00601 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
JHMANCOO_00602 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
JHMANCOO_00603 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHMANCOO_00604 2.1e-100 S Iron-sulfur cluster assembly protein
JHMANCOO_00605 1.5e-230 XK27_04775 S PAS domain
JHMANCOO_00606 1.4e-210 yttB EGP Major facilitator Superfamily
JHMANCOO_00607 0.0 pepO 3.4.24.71 O Peptidase family M13
JHMANCOO_00608 0.0 kup P Transport of potassium into the cell
JHMANCOO_00609 2.1e-68
JHMANCOO_00610 3.6e-09
JHMANCOO_00611 1.3e-26
JHMANCOO_00612 3.4e-37 S Protein of unknown function (DUF2922)
JHMANCOO_00613 9.5e-107 S SLAP domain
JHMANCOO_00614 6.1e-43
JHMANCOO_00615 3.6e-77 K DNA-templated transcription, initiation
JHMANCOO_00616 1.1e-25
JHMANCOO_00617 8.9e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
JHMANCOO_00618 7.9e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
JHMANCOO_00619 1.7e-79 S SLAP domain
JHMANCOO_00620 4.3e-75 L transposase, IS605 OrfB family
JHMANCOO_00622 5e-75 K Copper transport repressor CopY TcrY
JHMANCOO_00623 0.0 copB 3.6.3.4 P P-type ATPase
JHMANCOO_00625 3.8e-41 L transposase activity
JHMANCOO_00627 4.9e-177 MA20_14895 S Conserved hypothetical protein 698
JHMANCOO_00628 8.2e-68 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
JHMANCOO_00629 3.8e-284 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
JHMANCOO_00630 1.2e-30 copZ C Heavy-metal-associated domain
JHMANCOO_00631 6.1e-78 dps P Belongs to the Dps family
JHMANCOO_00632 1.9e-86 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
JHMANCOO_00633 2e-129 yobV1 K WYL domain
JHMANCOO_00634 1.8e-55 S pyridoxamine 5-phosphate
JHMANCOO_00635 3.8e-84 dps P Belongs to the Dps family
JHMANCOO_00636 2.8e-100 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
JHMANCOO_00637 2.9e-70 S Putative adhesin
JHMANCOO_00638 2e-72 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
JHMANCOO_00639 5.1e-235 mepA V MATE efflux family protein
JHMANCOO_00640 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
JHMANCOO_00641 2.9e-08
JHMANCOO_00642 6.6e-60
JHMANCOO_00643 1.1e-258 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
JHMANCOO_00644 6.4e-20 L Transposase DDE domain
JHMANCOO_00645 1.3e-83 L Transposase DDE domain
JHMANCOO_00646 0.0 UW LPXTG-motif cell wall anchor domain protein
JHMANCOO_00647 6.9e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
JHMANCOO_00648 3.8e-75 M Peptidase family M1 domain
JHMANCOO_00649 5e-151
JHMANCOO_00651 9.7e-247 ydaM M Glycosyl transferase
JHMANCOO_00652 2.5e-203 G Glycosyl hydrolases family 8
JHMANCOO_00653 6.6e-97 L Transposase and inactivated derivatives, IS30 family
JHMANCOO_00654 2.2e-12 L Transposase and inactivated derivatives, IS30 family
JHMANCOO_00655 2.1e-110 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JHMANCOO_00656 2.5e-29 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JHMANCOO_00657 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
JHMANCOO_00658 6.3e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
JHMANCOO_00659 7.6e-106 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
JHMANCOO_00660 3.9e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHMANCOO_00661 5.2e-122 lsa S ABC transporter
JHMANCOO_00662 5.7e-120 3.6.1.55 F NUDIX domain
JHMANCOO_00663 2.3e-243 brnQ U Component of the transport system for branched-chain amino acids
JHMANCOO_00664 5.3e-192 L Plasmid pRiA4b ORF-3-like protein
JHMANCOO_00666 9.5e-34 rmaI K Transcriptional regulator
JHMANCOO_00667 1.2e-170 lmrB EGP Major facilitator Superfamily
JHMANCOO_00668 4.9e-204 XK27_00915 C Luciferase-like monooxygenase
JHMANCOO_00669 6.5e-87 K GNAT family
JHMANCOO_00670 4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
JHMANCOO_00671 4e-287 P ABC transporter
JHMANCOO_00672 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
JHMANCOO_00673 1.1e-251 yifK E Amino acid permease
JHMANCOO_00674 5.3e-178 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JHMANCOO_00675 1.9e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JHMANCOO_00676 0.0 aha1 P E1-E2 ATPase
JHMANCOO_00677 5.8e-177 F DNA/RNA non-specific endonuclease
JHMANCOO_00678 2e-160 metQ2 P Belongs to the nlpA lipoprotein family
JHMANCOO_00679 2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JHMANCOO_00680 5.3e-74 metI P ABC transporter permease
JHMANCOO_00681 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
JHMANCOO_00682 4.3e-245 frdC 1.3.5.4 C FAD binding domain
JHMANCOO_00683 3.6e-163 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JHMANCOO_00684 4.1e-253 pepC 3.4.22.40 E Peptidase C1-like family
JHMANCOO_00685 3.8e-133 hxlA 6.2.1.3 H Aldolase/RraA
JHMANCOO_00686 4.7e-274 P Sodium:sulfate symporter transmembrane region
JHMANCOO_00687 4.1e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
JHMANCOO_00688 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
JHMANCOO_00689 8.2e-168 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
JHMANCOO_00690 4.9e-290 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
JHMANCOO_00691 9.3e-72 yeaL S Protein of unknown function (DUF441)
JHMANCOO_00692 1.8e-22
JHMANCOO_00693 3.6e-146 cbiQ P cobalt transport
JHMANCOO_00694 0.0 ykoD P ABC transporter, ATP-binding protein
JHMANCOO_00695 4.8e-94 S UPF0397 protein
JHMANCOO_00696 2.9e-66 S Domain of unknown function DUF1828
JHMANCOO_00697 5.5e-09
JHMANCOO_00698 1.3e-51
JHMANCOO_00699 2.6e-177 citR K Putative sugar-binding domain
JHMANCOO_00700 9.6e-250 yjjP S Putative threonine/serine exporter
JHMANCOO_00701 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JHMANCOO_00702 4.2e-175 prmA J Ribosomal protein L11 methyltransferase
JHMANCOO_00703 2.9e-60
JHMANCOO_00704 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JHMANCOO_00705 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JHMANCOO_00706 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
JHMANCOO_00707 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
JHMANCOO_00708 1.2e-222 patA 2.6.1.1 E Aminotransferase
JHMANCOO_00709 5.2e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JHMANCOO_00710 2.9e-213 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JHMANCOO_00711 5.6e-208 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
JHMANCOO_00712 0.0 yjbQ P TrkA C-terminal domain protein
JHMANCOO_00713 1.8e-116 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JHMANCOO_00714 2.8e-174 S Oxidoreductase family, NAD-binding Rossmann fold
JHMANCOO_00715 2.1e-135
JHMANCOO_00716 3.4e-135
JHMANCOO_00717 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JHMANCOO_00718 5.5e-98 G Aldose 1-epimerase
JHMANCOO_00719 1.5e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
JHMANCOO_00720 5.6e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JHMANCOO_00721 0.0 XK27_08315 M Sulfatase
JHMANCOO_00722 1.6e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JHMANCOO_00723 3.1e-54
JHMANCOO_00725 1.4e-258 pepC 3.4.22.40 E aminopeptidase
JHMANCOO_00726 1.2e-123 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
JHMANCOO_00727 1.7e-301 oppA E ABC transporter, substratebinding protein
JHMANCOO_00728 1.6e-310 oppA E ABC transporter, substratebinding protein
JHMANCOO_00729 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JHMANCOO_00730 2.4e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHMANCOO_00731 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHMANCOO_00732 2.7e-199 oppD P Belongs to the ABC transporter superfamily
JHMANCOO_00733 1.9e-175 oppF P Belongs to the ABC transporter superfamily
JHMANCOO_00734 1.1e-255 pepC 3.4.22.40 E aminopeptidase
JHMANCOO_00735 8.4e-67 hsp O Belongs to the small heat shock protein (HSP20) family
JHMANCOO_00736 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JHMANCOO_00737 1.2e-112
JHMANCOO_00739 3.5e-111 E Belongs to the SOS response-associated peptidase family
JHMANCOO_00740 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
JHMANCOO_00741 1.9e-88 comEB 3.5.4.12 F MafB19-like deaminase
JHMANCOO_00742 2e-103 S TPM domain
JHMANCOO_00743 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
JHMANCOO_00744 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHMANCOO_00745 5.7e-146 tatD L hydrolase, TatD family
JHMANCOO_00746 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JHMANCOO_00747 5.5e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JHMANCOO_00748 1.2e-39 veg S Biofilm formation stimulator VEG
JHMANCOO_00749 2.9e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
JHMANCOO_00750 8.9e-174 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JHMANCOO_00751 2.4e-80
JHMANCOO_00752 0.0 S SLAP domain
JHMANCOO_00753 2.3e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JHMANCOO_00754 4.2e-172 2.7.1.2 GK ROK family
JHMANCOO_00755 6.5e-44
JHMANCOO_00756 4.7e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
JHMANCOO_00757 2.6e-68 S Domain of unknown function (DUF1934)
JHMANCOO_00758 1.7e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JHMANCOO_00759 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JHMANCOO_00760 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JHMANCOO_00761 1.2e-75 K acetyltransferase
JHMANCOO_00762 4.4e-285 pipD E Dipeptidase
JHMANCOO_00763 3.5e-154 msmR K AraC-like ligand binding domain
JHMANCOO_00764 6.2e-222 pbuX F xanthine permease
JHMANCOO_00765 2.8e-105 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JHMANCOO_00766 7.1e-43 K Helix-turn-helix
JHMANCOO_00767 6.6e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JHMANCOO_00769 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
JHMANCOO_00770 4.3e-155 S reductase
JHMANCOO_00771 9.9e-149 yxeH S hydrolase
JHMANCOO_00772 1.5e-180 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHMANCOO_00773 4.8e-244 yfnA E Amino Acid
JHMANCOO_00774 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
JHMANCOO_00775 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JHMANCOO_00776 1.9e-242 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JHMANCOO_00777 1.9e-263 I Acyltransferase
JHMANCOO_00778 3.8e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JHMANCOO_00779 2.8e-140 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JHMANCOO_00780 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
JHMANCOO_00781 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JHMANCOO_00782 2.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JHMANCOO_00783 2.3e-23 S Protein of unknown function (DUF2929)
JHMANCOO_00784 0.0 dnaE 2.7.7.7 L DNA polymerase
JHMANCOO_00785 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JHMANCOO_00786 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JHMANCOO_00787 1.9e-169 cvfB S S1 domain
JHMANCOO_00788 9e-167 xerD D recombinase XerD
JHMANCOO_00789 6.7e-30 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JHMANCOO_00790 1e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JHMANCOO_00791 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JHMANCOO_00792 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JHMANCOO_00793 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JHMANCOO_00794 2.7e-18 M Lysin motif
JHMANCOO_00795 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JHMANCOO_00796 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
JHMANCOO_00797 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JHMANCOO_00798 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JHMANCOO_00799 1e-229 S Tetratricopeptide repeat protein
JHMANCOO_00800 5.8e-288 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHMANCOO_00801 1.1e-281 V ABC transporter transmembrane region
JHMANCOO_00802 5.6e-95 speG J Acetyltransferase (GNAT) domain
JHMANCOO_00803 1.4e-116 S Protein of unknown function (DUF2785)
JHMANCOO_00804 3.1e-47 S MazG-like family
JHMANCOO_00805 1.1e-43
JHMANCOO_00806 2.8e-23 S Protein of unknown function (DUF3923)
JHMANCOO_00807 6e-110 3.1.3.48 T Tyrosine phosphatase family
JHMANCOO_00808 5.1e-36 glsA 3.5.1.2 E Belongs to the glutaminase family
JHMANCOO_00809 4.4e-71 glsA 3.5.1.2 E Belongs to the glutaminase family
JHMANCOO_00810 1.3e-86 rimL J Acetyltransferase (GNAT) domain
JHMANCOO_00811 3.5e-77 2.3.1.57 K Acetyltransferase (GNAT) family
JHMANCOO_00812 1.4e-20 XK27_07525 3.6.1.55 F NUDIX domain
JHMANCOO_00813 9.1e-44 XK27_07525 3.6.1.55 F NUDIX domain
JHMANCOO_00814 3.4e-138 S Alpha/beta hydrolase family
JHMANCOO_00815 7.6e-53 yxaM EGP Major facilitator Superfamily
JHMANCOO_00816 1.4e-55 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
JHMANCOO_00817 7.4e-124 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
JHMANCOO_00818 2.6e-83 S AAA domain
JHMANCOO_00819 1.7e-137 2.7.1.89 M Phosphotransferase enzyme family
JHMANCOO_00820 3.5e-66 3.6.1.55 F NUDIX domain
JHMANCOO_00821 2.7e-140 2.4.2.3 F Phosphorylase superfamily
JHMANCOO_00822 9e-144 2.4.2.3 F Phosphorylase superfamily
JHMANCOO_00823 3.4e-149 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
JHMANCOO_00824 6.4e-167 yagE E Amino acid permease
JHMANCOO_00825 1.9e-86 3.4.21.96 S SLAP domain
JHMANCOO_00826 3.3e-158 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHMANCOO_00827 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JHMANCOO_00828 1.5e-107 hlyIII S protein, hemolysin III
JHMANCOO_00829 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
JHMANCOO_00830 7.1e-36 yozE S Belongs to the UPF0346 family
JHMANCOO_00831 8.9e-38 yjcE P NhaP-type Na H and K H
JHMANCOO_00832 1.1e-184 yjcE P Sodium proton antiporter
JHMANCOO_00833 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JHMANCOO_00834 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JHMANCOO_00835 4.9e-151 dprA LU DNA protecting protein DprA
JHMANCOO_00836 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHMANCOO_00837 2.3e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JHMANCOO_00838 3.2e-140 xerC D Phage integrase, N-terminal SAM-like domain
JHMANCOO_00839 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JHMANCOO_00840 3.4e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JHMANCOO_00841 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
JHMANCOO_00842 6.8e-71 C Aldo keto reductase
JHMANCOO_00843 2.9e-64 M LysM domain protein
JHMANCOO_00844 8e-35 S ASCH domain
JHMANCOO_00845 3.7e-47 3.6.4.12 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JHMANCOO_00846 7.4e-220 hsdM 2.1.1.72 V type I restriction-modification system
JHMANCOO_00847 1.5e-133 xerD L Phage integrase, N-terminal SAM-like domain
JHMANCOO_00848 7.9e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JHMANCOO_00849 2.7e-64 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JHMANCOO_00850 2.9e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
JHMANCOO_00851 1.2e-116 mmuP E amino acid
JHMANCOO_00852 2.9e-273 pepV 3.5.1.18 E dipeptidase PepV
JHMANCOO_00853 2.8e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
JHMANCOO_00854 1.7e-284 E Amino acid permease
JHMANCOO_00855 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
JHMANCOO_00856 1.6e-246 ynbB 4.4.1.1 P aluminum resistance
JHMANCOO_00857 6.1e-92 ktrA P domain protein
JHMANCOO_00858 2.7e-107 ktrB P Potassium uptake protein
JHMANCOO_00859 7.3e-57 ktrB P Potassium uptake protein
JHMANCOO_00860 2.6e-222 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
JHMANCOO_00861 6.8e-83 C Flavodoxin
JHMANCOO_00862 0.0 uvrA3 L excinuclease ABC, A subunit
JHMANCOO_00863 3.8e-47 uvrA3 L excinuclease ABC, A subunit
JHMANCOO_00864 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
JHMANCOO_00865 4.4e-112 3.6.1.27 I Acid phosphatase homologues
JHMANCOO_00866 7e-57 3.2.1.18 GH33 M Rib/alpha-like repeat
JHMANCOO_00868 5.6e-35 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JHMANCOO_00869 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
JHMANCOO_00870 1.3e-202 pbpX1 V Beta-lactamase
JHMANCOO_00871 1.9e-99 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
JHMANCOO_00872 7.5e-95 S ECF-type riboflavin transporter, S component
JHMANCOO_00873 2e-230 S Putative peptidoglycan binding domain
JHMANCOO_00874 1.4e-83 K Acetyltransferase (GNAT) domain
JHMANCOO_00875 3.7e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JHMANCOO_00876 7.3e-191 yrvN L AAA C-terminal domain
JHMANCOO_00877 1.1e-63 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JHMANCOO_00878 8.3e-66 treB G phosphotransferase system
JHMANCOO_00879 2.7e-266 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
JHMANCOO_00880 3.7e-17
JHMANCOO_00881 2.6e-236 G Bacterial extracellular solute-binding protein
JHMANCOO_00882 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
JHMANCOO_00883 2.9e-237 XK27_01810 S Calcineurin-like phosphoesterase
JHMANCOO_00885 0.0 S SLAP domain
JHMANCOO_00886 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
JHMANCOO_00887 7.2e-259 hsdM 2.1.1.72 V type I restriction-modification system
JHMANCOO_00888 1.4e-17 S Sel1-like repeats.
JHMANCOO_00889 3.6e-76 S HIRAN
JHMANCOO_00890 6.4e-31
JHMANCOO_00891 1.7e-182
JHMANCOO_00892 7.3e-98 3.1.4.37 S AAA domain
JHMANCOO_00893 6.9e-09 S Sel1-like repeats.
JHMANCOO_00894 5.1e-44 S Sel1-like repeats.
JHMANCOO_00896 1.2e-104 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
JHMANCOO_00897 1.3e-51
JHMANCOO_00898 2.2e-283 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
JHMANCOO_00899 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JHMANCOO_00900 1.6e-168 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JHMANCOO_00901 4.6e-199 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JHMANCOO_00902 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
JHMANCOO_00903 0.0 FbpA K Fibronectin-binding protein
JHMANCOO_00904 1.1e-66
JHMANCOO_00905 1.3e-159 degV S EDD domain protein, DegV family
JHMANCOO_00906 2.9e-305 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JHMANCOO_00907 1.8e-203 xerS L Belongs to the 'phage' integrase family
JHMANCOO_00908 4.1e-67
JHMANCOO_00909 1.8e-110 XK27_00160 S Domain of unknown function (DUF5052)
JHMANCOO_00910 1.5e-211 M Glycosyl hydrolases family 25
JHMANCOO_00911 2e-39 S Transglycosylase associated protein
JHMANCOO_00912 2.7e-123 yoaK S Protein of unknown function (DUF1275)
JHMANCOO_00913 4e-57 K Helix-turn-helix domain
JHMANCOO_00914 1.1e-112 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JHMANCOO_00915 2.5e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
JHMANCOO_00916 4.3e-183 K Transcriptional regulator
JHMANCOO_00917 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JHMANCOO_00918 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JHMANCOO_00919 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JHMANCOO_00920 0.0 snf 2.7.11.1 KL domain protein
JHMANCOO_00921 2e-28
JHMANCOO_00922 5.6e-36
JHMANCOO_00923 4.5e-105 pncA Q Isochorismatase family
JHMANCOO_00924 7.6e-119
JHMANCOO_00927 3.6e-63
JHMANCOO_00928 1.4e-34
JHMANCOO_00929 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
JHMANCOO_00930 4.9e-78
JHMANCOO_00931 4e-242 cpdA S Calcineurin-like phosphoesterase
JHMANCOO_00932 1.8e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JHMANCOO_00933 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JHMANCOO_00934 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JHMANCOO_00935 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
JHMANCOO_00936 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JHMANCOO_00937 1.3e-114 dnaD L DnaD domain protein
JHMANCOO_00938 1.2e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
JHMANCOO_00939 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JHMANCOO_00940 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JHMANCOO_00941 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
JHMANCOO_00942 2.2e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
JHMANCOO_00943 3.7e-179 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
JHMANCOO_00944 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
JHMANCOO_00945 2.4e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JHMANCOO_00946 2.2e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
JHMANCOO_00947 1.7e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
JHMANCOO_00948 1.8e-167
JHMANCOO_00949 2e-143
JHMANCOO_00950 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JHMANCOO_00951 7.3e-67 UW LPXTG-motif cell wall anchor domain protein
JHMANCOO_00952 1.4e-51 L Helix-turn-helix domain
JHMANCOO_00953 7.6e-79 L Helix-turn-helix domain
JHMANCOO_00955 4.9e-47 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
JHMANCOO_00956 7.9e-20 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
JHMANCOO_00957 5.1e-59 hxlR K Transcriptional regulator, HxlR family
JHMANCOO_00958 3.2e-197 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
JHMANCOO_00959 6.7e-95 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JHMANCOO_00960 4e-95
JHMANCOO_00961 6.6e-105
JHMANCOO_00962 8.3e-127
JHMANCOO_00963 2.4e-122 skfE V ATPases associated with a variety of cellular activities
JHMANCOO_00964 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
JHMANCOO_00965 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JHMANCOO_00966 2.9e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JHMANCOO_00967 2.1e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
JHMANCOO_00968 6.2e-81 mutT 3.6.1.55 F NUDIX domain
JHMANCOO_00969 8e-128 S Peptidase family M23
JHMANCOO_00970 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JHMANCOO_00971 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JHMANCOO_00972 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JHMANCOO_00973 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JHMANCOO_00974 1.1e-136 recO L Involved in DNA repair and RecF pathway recombination
JHMANCOO_00975 3.1e-20 L COG3547 Transposase and inactivated derivatives
JHMANCOO_00976 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JHMANCOO_00977 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JHMANCOO_00978 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
JHMANCOO_00979 2.2e-70 yqeY S YqeY-like protein
JHMANCOO_00980 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JHMANCOO_00981 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
JHMANCOO_00982 4.1e-65 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
JHMANCOO_00983 3e-173 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JHMANCOO_00984 1.1e-121 casE S CRISPR_assoc
JHMANCOO_00985 6.8e-133 casD S CRISPR-associated protein (Cas_Cas5)
JHMANCOO_00986 4.9e-199 casC L CT1975-like protein
JHMANCOO_00987 8.8e-110 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
JHMANCOO_00988 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
JHMANCOO_00989 0.0 cas3 L CRISPR-associated helicase cas3
JHMANCOO_00990 1.1e-46
JHMANCOO_00991 3.9e-10 K TRANSCRIPTIONal
JHMANCOO_00992 3.7e-111 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
JHMANCOO_00993 1.3e-93 dps P Belongs to the Dps family
JHMANCOO_00994 1e-34 copZ C Heavy-metal-associated domain
JHMANCOO_00995 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
JHMANCOO_00996 1.3e-102
JHMANCOO_00997 2e-117 S Peptidase family M23
JHMANCOO_00998 6.5e-107 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHMANCOO_01000 3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHMANCOO_01001 3.6e-117
JHMANCOO_01002 6.6e-159 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JHMANCOO_01003 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
JHMANCOO_01004 5.2e-281 thrC 4.2.3.1 E Threonine synthase
JHMANCOO_01005 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
JHMANCOO_01006 7.9e-31 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
JHMANCOO_01007 4.9e-48 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
JHMANCOO_01008 2.3e-63 hipB K sequence-specific DNA binding
JHMANCOO_01009 5.4e-284 V ABC-type multidrug transport system, ATPase and permease components
JHMANCOO_01010 7.6e-286 V ABC-type multidrug transport system, ATPase and permease components
JHMANCOO_01011 8e-95
JHMANCOO_01012 1.9e-118 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
JHMANCOO_01013 9e-98
JHMANCOO_01014 2e-109 K LysR substrate binding domain
JHMANCOO_01015 1e-20
JHMANCOO_01016 1.3e-213 S Sterol carrier protein domain
JHMANCOO_01017 1.3e-96 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
JHMANCOO_01018 2.1e-107 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
JHMANCOO_01019 3.9e-37 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JHMANCOO_01020 4e-234 arcA 3.5.3.6 E Arginine
JHMANCOO_01021 2.6e-136 lysR5 K LysR substrate binding domain
JHMANCOO_01022 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
JHMANCOO_01023 1.5e-49 S Metal binding domain of Ada
JHMANCOO_01024 3e-43 ybhL S Belongs to the BI1 family
JHMANCOO_01025 1.1e-211 S Bacterial protein of unknown function (DUF871)
JHMANCOO_01026 1.1e-200 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
JHMANCOO_01027 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JHMANCOO_01028 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
JHMANCOO_01029 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JHMANCOO_01030 5.8e-203 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JHMANCOO_01031 0.0 dnaK O Heat shock 70 kDa protein
JHMANCOO_01032 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JHMANCOO_01033 4.5e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JHMANCOO_01034 7.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JHMANCOO_01035 2.2e-157 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JHMANCOO_01036 3e-60 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JHMANCOO_01037 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JHMANCOO_01038 9.3e-47 rplGA J ribosomal protein
JHMANCOO_01039 8.8e-47 ylxR K Protein of unknown function (DUF448)
JHMANCOO_01040 2.6e-198 nusA K Participates in both transcription termination and antitermination
JHMANCOO_01041 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
JHMANCOO_01042 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JHMANCOO_01043 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JHMANCOO_01044 2e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
JHMANCOO_01045 1.5e-141 cdsA 2.7.7.41 I Belongs to the CDS family
JHMANCOO_01046 1.9e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JHMANCOO_01047 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JHMANCOO_01048 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JHMANCOO_01049 8.3e-185 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JHMANCOO_01050 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
JHMANCOO_01051 6.3e-193 yabB 2.1.1.223 L Methyltransferase small domain
JHMANCOO_01052 1.9e-112 plsC 2.3.1.51 I Acyltransferase
JHMANCOO_01053 1.4e-225 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
JHMANCOO_01054 5.3e-99 L An automated process has identified a potential problem with this gene model
JHMANCOO_01055 1.3e-132 S SLAP domain
JHMANCOO_01056 0.0 oppA E ABC transporter substrate-binding protein
JHMANCOO_01057 6.4e-84 dps P Belongs to the Dps family
JHMANCOO_01058 3.1e-22 npr 1.11.1.1 C NADH oxidase
JHMANCOO_01059 0.0 pepO 3.4.24.71 O Peptidase family M13
JHMANCOO_01060 0.0 mdlB V ABC transporter
JHMANCOO_01061 0.0 mdlA V ABC transporter
JHMANCOO_01062 3.3e-30 yneF S Uncharacterised protein family (UPF0154)
JHMANCOO_01063 1.4e-38 ynzC S UPF0291 protein
JHMANCOO_01064 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JHMANCOO_01065 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
JHMANCOO_01066 4.9e-122 ung2 3.2.2.27 L Uracil-DNA glycosylase
JHMANCOO_01067 4.2e-214 S SLAP domain
JHMANCOO_01068 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JHMANCOO_01069 5e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JHMANCOO_01070 2.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JHMANCOO_01071 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JHMANCOO_01072 5.8e-229 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JHMANCOO_01073 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JHMANCOO_01074 1.7e-260 yfnA E amino acid
JHMANCOO_01075 0.0 V FtsX-like permease family
JHMANCOO_01076 2.4e-133 cysA V ABC transporter, ATP-binding protein
JHMANCOO_01077 4.2e-08
JHMANCOO_01078 5.5e-288 pipD E Dipeptidase
JHMANCOO_01079 1.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JHMANCOO_01080 0.0 smc D Required for chromosome condensation and partitioning
JHMANCOO_01081 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JHMANCOO_01082 5.4e-309 oppA E ABC transporter substrate-binding protein
JHMANCOO_01083 7.7e-308 oppA E ABC transporter substrate-binding protein
JHMANCOO_01084 6.2e-131 oppC P Binding-protein-dependent transport system inner membrane component
JHMANCOO_01085 7.5e-172 oppB P ABC transporter permease
JHMANCOO_01086 8.8e-168 oppF P Belongs to the ABC transporter superfamily
JHMANCOO_01087 1.1e-192 oppD P Belongs to the ABC transporter superfamily
JHMANCOO_01088 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JHMANCOO_01089 7.1e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JHMANCOO_01090 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JHMANCOO_01091 2e-305 yloV S DAK2 domain fusion protein YloV
JHMANCOO_01092 4e-57 asp S Asp23 family, cell envelope-related function
JHMANCOO_01093 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JHMANCOO_01094 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
JHMANCOO_01095 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JHMANCOO_01096 3.3e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JHMANCOO_01097 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
JHMANCOO_01098 1.3e-139 stp 3.1.3.16 T phosphatase
JHMANCOO_01099 1.8e-243 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JHMANCOO_01100 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JHMANCOO_01101 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JHMANCOO_01102 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
JHMANCOO_01103 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
JHMANCOO_01104 1.1e-77 6.3.3.2 S ASCH
JHMANCOO_01105 8.7e-309 recN L May be involved in recombinational repair of damaged DNA
JHMANCOO_01106 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
JHMANCOO_01107 7e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JHMANCOO_01108 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JHMANCOO_01109 3.8e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JHMANCOO_01110 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JHMANCOO_01111 2.1e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JHMANCOO_01112 3.4e-71 yqhY S Asp23 family, cell envelope-related function
JHMANCOO_01113 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JHMANCOO_01114 3e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
JHMANCOO_01115 7.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JHMANCOO_01116 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
JHMANCOO_01117 4.1e-150 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHMANCOO_01118 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
JHMANCOO_01120 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
JHMANCOO_01121 1e-299 S Predicted membrane protein (DUF2207)
JHMANCOO_01122 2.5e-158 cinI S Serine hydrolase (FSH1)
JHMANCOO_01123 2.4e-207 M Glycosyl hydrolases family 25
JHMANCOO_01125 2.9e-178 I Carboxylesterase family
JHMANCOO_01126 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
JHMANCOO_01127 1.2e-278 V ABC-type multidrug transport system, ATPase and permease components
JHMANCOO_01128 1.6e-291 V ABC-type multidrug transport system, ATPase and permease components
JHMANCOO_01129 1.7e-148 S haloacid dehalogenase-like hydrolase
JHMANCOO_01130 2.6e-52
JHMANCOO_01131 1.9e-37
JHMANCOO_01132 4.5e-42 S Alpha beta hydrolase
JHMANCOO_01133 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
JHMANCOO_01134 6.4e-116 L Resolvase, N-terminal
JHMANCOO_01135 1.3e-251 L Putative transposase DNA-binding domain
JHMANCOO_01136 6.1e-112 yfeO P Voltage gated chloride channel
JHMANCOO_01137 4.7e-185 5.3.3.2 C FMN-dependent dehydrogenase
JHMANCOO_01138 3.1e-51
JHMANCOO_01139 4.7e-42
JHMANCOO_01140 3.7e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JHMANCOO_01141 4.6e-299 ybeC E amino acid
JHMANCOO_01142 1.4e-155 S Sucrose-6F-phosphate phosphohydrolase
JHMANCOO_01143 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
JHMANCOO_01144 2.5e-39 rpmE2 J Ribosomal protein L31
JHMANCOO_01145 1.3e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JHMANCOO_01146 4.8e-250 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JHMANCOO_01147 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JHMANCOO_01148 2.9e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHMANCOO_01149 3.4e-129 S (CBS) domain
JHMANCOO_01150 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JHMANCOO_01151 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JHMANCOO_01152 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JHMANCOO_01153 1.6e-33 yabO J S4 domain protein
JHMANCOO_01154 6.8e-60 divIC D Septum formation initiator
JHMANCOO_01155 6.3e-63 yabR J S1 RNA binding domain
JHMANCOO_01156 1.3e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JHMANCOO_01157 1.3e-180 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JHMANCOO_01158 4.2e-141 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JHMANCOO_01159 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JHMANCOO_01160 2.3e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHMANCOO_01161 1.1e-284 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JHMANCOO_01164 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
JHMANCOO_01165 1.6e-08
JHMANCOO_01167 1.1e-80 yebR 1.8.4.14 T GAF domain-containing protein
JHMANCOO_01168 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
JHMANCOO_01169 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JHMANCOO_01170 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JHMANCOO_01171 8.1e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
JHMANCOO_01172 1.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JHMANCOO_01173 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JHMANCOO_01174 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JHMANCOO_01175 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
JHMANCOO_01176 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JHMANCOO_01177 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
JHMANCOO_01178 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JHMANCOO_01179 7.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JHMANCOO_01180 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JHMANCOO_01181 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JHMANCOO_01182 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JHMANCOO_01183 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JHMANCOO_01184 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
JHMANCOO_01185 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JHMANCOO_01186 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JHMANCOO_01187 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JHMANCOO_01188 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JHMANCOO_01189 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JHMANCOO_01190 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JHMANCOO_01191 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JHMANCOO_01192 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JHMANCOO_01193 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JHMANCOO_01194 2.3e-24 rpmD J Ribosomal protein L30
JHMANCOO_01195 2.6e-71 rplO J Binds to the 23S rRNA
JHMANCOO_01196 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JHMANCOO_01197 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JHMANCOO_01198 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JHMANCOO_01199 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JHMANCOO_01200 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JHMANCOO_01201 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JHMANCOO_01202 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JHMANCOO_01203 1.4e-60 rplQ J Ribosomal protein L17
JHMANCOO_01204 3.7e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JHMANCOO_01205 5.4e-158 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JHMANCOO_01206 3.5e-138 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JHMANCOO_01207 7.3e-149 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JHMANCOO_01208 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JHMANCOO_01209 1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
JHMANCOO_01210 2.3e-150 M Belongs to the glycosyl hydrolase 28 family
JHMANCOO_01211 1e-78 K Acetyltransferase (GNAT) domain
JHMANCOO_01212 3.3e-106 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
JHMANCOO_01213 1.9e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
JHMANCOO_01214 1.1e-133 S membrane transporter protein
JHMANCOO_01215 1.5e-126 gpmB G Belongs to the phosphoglycerate mutase family
JHMANCOO_01216 5.1e-162 czcD P cation diffusion facilitator family transporter
JHMANCOO_01217 1.4e-23
JHMANCOO_01218 5.8e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JHMANCOO_01219 1.1e-183 S AAA domain
JHMANCOO_01220 8.1e-51
JHMANCOO_01221 3e-267 pepC 3.4.22.40 E Peptidase C1-like family
JHMANCOO_01222 1.9e-52
JHMANCOO_01223 5.2e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
JHMANCOO_01224 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JHMANCOO_01225 1.9e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JHMANCOO_01226 3.2e-275 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JHMANCOO_01227 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JHMANCOO_01228 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHMANCOO_01229 5.5e-95 sigH K Belongs to the sigma-70 factor family
JHMANCOO_01230 1.7e-34
JHMANCOO_01231 1.3e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
JHMANCOO_01232 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JHMANCOO_01233 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
JHMANCOO_01234 1.1e-101 nusG K Participates in transcription elongation, termination and antitermination
JHMANCOO_01235 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JHMANCOO_01236 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JHMANCOO_01237 7.3e-158 pstS P Phosphate
JHMANCOO_01238 3.9e-163 pstC P probably responsible for the translocation of the substrate across the membrane
JHMANCOO_01239 1.2e-155 pstA P Phosphate transport system permease protein PstA
JHMANCOO_01240 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JHMANCOO_01241 7.8e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JHMANCOO_01242 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
JHMANCOO_01243 4e-89 L An automated process has identified a potential problem with this gene model
JHMANCOO_01244 6.1e-149 glcU U sugar transport
JHMANCOO_01245 1.6e-248 lctP C L-lactate permease
JHMANCOO_01246 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
JHMANCOO_01247 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JHMANCOO_01248 4e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JHMANCOO_01249 7.2e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JHMANCOO_01250 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JHMANCOO_01251 6.3e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JHMANCOO_01252 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JHMANCOO_01253 1.4e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JHMANCOO_01254 5.2e-54 clcA P chloride
JHMANCOO_01255 3.5e-285 lsa S ABC transporter
JHMANCOO_01256 1.7e-42
JHMANCOO_01257 2e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
JHMANCOO_01258 1e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
JHMANCOO_01259 1.3e-51 S Iron-sulfur cluster assembly protein
JHMANCOO_01260 6.6e-99 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
JHMANCOO_01261 9e-11 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
JHMANCOO_01262 2.9e-23 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
JHMANCOO_01263 9.8e-244 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
JHMANCOO_01264 4.4e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHMANCOO_01265 2.7e-277 yjeM E Amino Acid
JHMANCOO_01266 5.4e-266 S SLAP domain
JHMANCOO_01267 1.1e-280
JHMANCOO_01268 2.2e-78
JHMANCOO_01269 1.6e-88 S Protein of unknown function (DUF805)
JHMANCOO_01270 1.7e-69 O OsmC-like protein
JHMANCOO_01271 1.2e-208 EGP Major facilitator Superfamily
JHMANCOO_01272 1.2e-220 sptS 2.7.13.3 T Histidine kinase
JHMANCOO_01273 3.8e-106 K response regulator
JHMANCOO_01274 3.6e-111 2.7.6.5 T Region found in RelA / SpoT proteins
JHMANCOO_01275 7.8e-282 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
JHMANCOO_01276 0.0 rafA 3.2.1.22 G alpha-galactosidase
JHMANCOO_01277 2.8e-210 msmX P Belongs to the ABC transporter superfamily
JHMANCOO_01278 5.2e-153 msmG P Binding-protein-dependent transport system inner membrane component
JHMANCOO_01279 4.8e-157 msmF P Binding-protein-dependent transport system inner membrane component
JHMANCOO_01280 2.7e-238 msmE G Bacterial extracellular solute-binding protein
JHMANCOO_01281 2.9e-71 scrR K Periplasmic binding protein domain
JHMANCOO_01282 5.5e-36
JHMANCOO_01283 4.5e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JHMANCOO_01284 5.7e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JHMANCOO_01285 5.3e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JHMANCOO_01286 0.0 lacZ 3.2.1.23 G -beta-galactosidase
JHMANCOO_01287 0.0 lacS G Transporter
JHMANCOO_01288 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
JHMANCOO_01289 3.5e-145 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
JHMANCOO_01290 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JHMANCOO_01291 1.5e-121 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
JHMANCOO_01292 1.4e-54 dhaM 2.7.1.121 S PTS system fructose IIA component
JHMANCOO_01293 8.5e-94 dhaL 2.7.1.121 S Dak2
JHMANCOO_01294 3.4e-175 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
JHMANCOO_01295 1.3e-252 E Amino acid permease
JHMANCOO_01296 9.1e-59 L An automated process has identified a potential problem with this gene model
JHMANCOO_01297 3.6e-25 L An automated process has identified a potential problem with this gene model
JHMANCOO_01298 1.4e-33
JHMANCOO_01300 1.2e-31 S protein encoded in hypervariable junctions of pilus gene clusters
JHMANCOO_01301 1.8e-13 hicA S HicA toxin of bacterial toxin-antitoxin,
JHMANCOO_01302 1.6e-148
JHMANCOO_01303 4.3e-169
JHMANCOO_01304 2e-263 glnA 6.3.1.2 E glutamine synthetase
JHMANCOO_01305 2.9e-224 ynbB 4.4.1.1 P aluminum resistance
JHMANCOO_01306 2e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JHMANCOO_01307 1.5e-65 yqhL P Rhodanese-like protein
JHMANCOO_01308 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
JHMANCOO_01309 1.1e-119 gluP 3.4.21.105 S Rhomboid family
JHMANCOO_01310 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JHMANCOO_01311 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JHMANCOO_01312 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
JHMANCOO_01313 0.0 S membrane
JHMANCOO_01314 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
JHMANCOO_01315 1.3e-38 S RelB antitoxin
JHMANCOO_01316 1.2e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
JHMANCOO_01317 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JHMANCOO_01318 5.7e-138 fhuC 3.6.3.34 HP abc transporter atp-binding protein
JHMANCOO_01319 7.3e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHMANCOO_01320 6.7e-159 isdE P Periplasmic binding protein
JHMANCOO_01321 5.7e-124 M Iron Transport-associated domain
JHMANCOO_01322 3e-09 isdH M Iron Transport-associated domain
JHMANCOO_01323 2.2e-89
JHMANCOO_01324 6.4e-113 S SLAP domain
JHMANCOO_01325 1.7e-50 S Uncharacterized protein conserved in bacteria (DUF2263)
JHMANCOO_01326 4.4e-83 S An automated process has identified a potential problem with this gene model
JHMANCOO_01327 5.7e-136 S Protein of unknown function (DUF3100)
JHMANCOO_01328 1e-245 3.5.1.47 S Peptidase dimerisation domain
JHMANCOO_01329 5.6e-233 Q Imidazolonepropionase and related amidohydrolases
JHMANCOO_01330 2.3e-311 oppA E ABC transporter
JHMANCOO_01331 2.4e-147 S Sucrose-6F-phosphate phosphohydrolase
JHMANCOO_01332 0.0 mco Q Multicopper oxidase
JHMANCOO_01333 5.7e-25
JHMANCOO_01334 1.6e-157 metQ1 P Belongs to the nlpA lipoprotein family
JHMANCOO_01335 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
JHMANCOO_01336 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JHMANCOO_01337 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JHMANCOO_01338 2.7e-199 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JHMANCOO_01339 2.9e-162 cjaA ET ABC transporter substrate-binding protein
JHMANCOO_01340 9.7e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JHMANCOO_01341 2.8e-117 P ABC transporter permease
JHMANCOO_01342 5.1e-111 papP P ABC transporter, permease protein
JHMANCOO_01344 3.6e-63 yodB K Transcriptional regulator, HxlR family
JHMANCOO_01345 6.7e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHMANCOO_01346 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JHMANCOO_01347 7.6e-164 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JHMANCOO_01348 4.2e-86 S Aminoacyl-tRNA editing domain
JHMANCOO_01349 9.4e-225 S SLAP domain
JHMANCOO_01350 1.8e-50 S CAAX protease self-immunity
JHMANCOO_01351 1.3e-277 arlS 2.7.13.3 T Histidine kinase
JHMANCOO_01352 1.6e-126 K response regulator
JHMANCOO_01353 2.3e-96 yceD S Uncharacterized ACR, COG1399
JHMANCOO_01354 5.6e-206 ylbM S Belongs to the UPF0348 family
JHMANCOO_01355 2.6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JHMANCOO_01356 1.1e-107 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
JHMANCOO_01357 5.5e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JHMANCOO_01358 1.1e-201 yqeH S Ribosome biogenesis GTPase YqeH
JHMANCOO_01359 2.9e-85 yqeG S HAD phosphatase, family IIIA
JHMANCOO_01360 9.5e-154 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JHMANCOO_01361 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JHMANCOO_01362 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JHMANCOO_01363 2.2e-73 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JHMANCOO_01364 7.1e-106 yyaR K Acetyltransferase (GNAT) domain
JHMANCOO_01365 8.8e-123 S domain protein
JHMANCOO_01366 8.3e-168 V ABC transporter
JHMANCOO_01367 3.8e-75 S Protein of unknown function (DUF3021)
JHMANCOO_01368 7.8e-76 K LytTr DNA-binding domain
JHMANCOO_01369 3.5e-91
JHMANCOO_01370 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JHMANCOO_01371 3.6e-168 dnaI L Primosomal protein DnaI
JHMANCOO_01372 3e-251 dnaB L Replication initiation and membrane attachment
JHMANCOO_01373 4.6e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JHMANCOO_01374 3.4e-106 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JHMANCOO_01375 1.4e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JHMANCOO_01376 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHMANCOO_01377 2.7e-136 qmcA O prohibitin homologues
JHMANCOO_01378 8e-51 L RelB antitoxin
JHMANCOO_01379 9.3e-194 S Bacteriocin helveticin-J
JHMANCOO_01380 2.9e-238 M Peptidase family M1 domain
JHMANCOO_01381 2e-32 M Peptidase family M1 domain
JHMANCOO_01382 4.3e-175 S SLAP domain
JHMANCOO_01383 1.2e-236 mepA V MATE efflux family protein
JHMANCOO_01384 4.2e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JHMANCOO_01385 1.1e-218
JHMANCOO_01386 7.7e-33 S Psort location Cytoplasmic, score
JHMANCOO_01388 2e-120 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JHMANCOO_01389 1.1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JHMANCOO_01391 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JHMANCOO_01392 2.9e-221 ecsB U ABC transporter
JHMANCOO_01393 2e-135 ecsA V ABC transporter, ATP-binding protein
JHMANCOO_01394 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
JHMANCOO_01395 3.9e-25
JHMANCOO_01396 1.5e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JHMANCOO_01397 7.6e-73 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
JHMANCOO_01398 2e-272
JHMANCOO_01399 4.9e-187 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
JHMANCOO_01400 0.0 L AAA domain
JHMANCOO_01401 1.3e-229 yhaO L Ser Thr phosphatase family protein
JHMANCOO_01402 7.2e-56 yheA S Belongs to the UPF0342 family
JHMANCOO_01403 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JHMANCOO_01404 6.5e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JHMANCOO_01405 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
JHMANCOO_01406 3.6e-111 G Phosphoglycerate mutase family
JHMANCOO_01407 5.7e-74 S Membrane protein involved in the export of O-antigen and teichoic acid
JHMANCOO_01408 6e-90 S Core-2/I-Branching enzyme
JHMANCOO_01409 6.8e-30 S Acyltransferase family
JHMANCOO_01410 5.6e-31 L Transposase and inactivated derivatives, IS30 family
JHMANCOO_01411 7.8e-13 GT2,GT4 M family 8
JHMANCOO_01412 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JHMANCOO_01413 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JHMANCOO_01414 2.3e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
JHMANCOO_01415 1.1e-115 rsmC 2.1.1.172 J Methyltransferase
JHMANCOO_01416 9e-26
JHMANCOO_01417 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JHMANCOO_01418 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JHMANCOO_01419 2.2e-105 2.4.1.58 GT8 M family 8
JHMANCOO_01420 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
JHMANCOO_01421 6.7e-51 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JHMANCOO_01422 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JHMANCOO_01423 2.4e-34 S Protein of unknown function (DUF2508)
JHMANCOO_01424 2.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JHMANCOO_01425 8.9e-53 yaaQ S Cyclic-di-AMP receptor
JHMANCOO_01426 3e-156 holB 2.7.7.7 L DNA polymerase III
JHMANCOO_01427 1.8e-59 yabA L Involved in initiation control of chromosome replication
JHMANCOO_01428 7.9e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JHMANCOO_01429 8.9e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
JHMANCOO_01430 4e-87 S ECF transporter, substrate-specific component
JHMANCOO_01431 5.3e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
JHMANCOO_01432 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
JHMANCOO_01433 1.8e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JHMANCOO_01434 1.3e-51 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
JHMANCOO_01435 4.2e-167 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
JHMANCOO_01436 7e-129 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
JHMANCOO_01437 1.5e-17 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
JHMANCOO_01438 0.0 uup S ABC transporter, ATP-binding protein
JHMANCOO_01439 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JHMANCOO_01440 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
JHMANCOO_01441 2e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
JHMANCOO_01442 1.8e-177 S PFAM Archaeal ATPase
JHMANCOO_01443 5.6e-164 L Transposase and inactivated derivatives, IS30 family
JHMANCOO_01444 1.3e-235 L transposase, IS605 OrfB family
JHMANCOO_01445 3.7e-72 yniG EGP Major facilitator Superfamily
JHMANCOO_01447 4.8e-106
JHMANCOO_01448 1.6e-135 K LytTr DNA-binding domain
JHMANCOO_01449 1.2e-103 2.7.13.3 T GHKL domain
JHMANCOO_01450 3.6e-45
JHMANCOO_01452 2.3e-77 menA 2.5.1.74 H UbiA prenyltransferase family
JHMANCOO_01453 7.6e-97 3.6.1.55 L NUDIX domain
JHMANCOO_01454 3e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
JHMANCOO_01455 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
JHMANCOO_01456 5.1e-98 M ErfK YbiS YcfS YnhG
JHMANCOO_01457 8.1e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JHMANCOO_01458 1.4e-242 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JHMANCOO_01460 4.3e-47 pspC KT PspC domain
JHMANCOO_01461 8e-299 ytgP S Polysaccharide biosynthesis protein
JHMANCOO_01462 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JHMANCOO_01463 3.8e-122 3.6.1.27 I Acid phosphatase homologues
JHMANCOO_01464 9.8e-169 K LysR substrate binding domain
JHMANCOO_01465 7.8e-85 3.6.4.12 S PD-(D/E)XK nuclease family transposase
JHMANCOO_01466 3.1e-231 ndh 1.6.99.3 C NADH dehydrogenase
JHMANCOO_01467 3e-162 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
JHMANCOO_01468 3.4e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JHMANCOO_01469 7.5e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
JHMANCOO_01470 4.6e-268 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JHMANCOO_01471 1.2e-300 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
JHMANCOO_01472 5.2e-163 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
JHMANCOO_01473 8.2e-263 cydA 1.10.3.14 C ubiquinol oxidase
JHMANCOO_01474 8.4e-108 ybbH_2 K rpiR family
JHMANCOO_01475 5.7e-149 L COG3385 FOG Transposase and inactivated derivatives
JHMANCOO_01476 8.7e-70 S 2-Nitropropane dioxygenase
JHMANCOO_01477 5e-117 K Transcriptional regulator, LysR family
JHMANCOO_01478 1.3e-235 I Acyl-CoA dehydrogenase, N-terminal domain
JHMANCOO_01479 1.2e-225 MA20_04610 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
JHMANCOO_01480 2.2e-186 I Acyl-CoA dehydrogenase, C-terminal domain
JHMANCOO_01481 6.4e-54 fixA C Electron transfer flavoprotein domain
JHMANCOO_01482 2.8e-255 qacA EGP Major facilitator Superfamily
JHMANCOO_01483 1.6e-219 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JHMANCOO_01486 5.7e-166 psaA P Belongs to the bacterial solute-binding protein 9 family
JHMANCOO_01489 1.5e-37 UW LPXTG-motif cell wall anchor domain protein
JHMANCOO_01490 1e-210 UW LPXTG-motif cell wall anchor domain protein
JHMANCOO_01491 8.6e-98 UW LPXTG-motif cell wall anchor domain protein
JHMANCOO_01492 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JHMANCOO_01493 7.5e-100 J Acetyltransferase (GNAT) domain
JHMANCOO_01494 1.4e-110 yjbF S SNARE associated Golgi protein
JHMANCOO_01495 1.4e-152 I alpha/beta hydrolase fold
JHMANCOO_01496 1.5e-158 hipB K Helix-turn-helix
JHMANCOO_01497 3.1e-92 F Nucleoside 2-deoxyribosyltransferase
JHMANCOO_01498 4.6e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
JHMANCOO_01499 1.5e-162
JHMANCOO_01500 0.0 ydgH S MMPL family
JHMANCOO_01501 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
JHMANCOO_01502 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
JHMANCOO_01503 1.8e-154 corA P CorA-like Mg2+ transporter protein
JHMANCOO_01504 2.3e-240 G Bacterial extracellular solute-binding protein
JHMANCOO_01505 2.4e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
JHMANCOO_01506 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
JHMANCOO_01507 7.3e-158 gtsB P ABC-type sugar transport systems, permease components
JHMANCOO_01508 1.1e-203 malK P ATPases associated with a variety of cellular activities
JHMANCOO_01509 4.1e-283 pipD E Dipeptidase
JHMANCOO_01510 5.5e-158 endA F DNA RNA non-specific endonuclease
JHMANCOO_01511 8.2e-179 dnaQ 2.7.7.7 L EXOIII
JHMANCOO_01512 2.4e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JHMANCOO_01513 3e-116 yviA S Protein of unknown function (DUF421)
JHMANCOO_01514 1.1e-72 S Protein of unknown function (DUF3290)
JHMANCOO_01515 9e-141 pnuC H nicotinamide mononucleotide transporter
JHMANCOO_01516 1.4e-13
JHMANCOO_01517 2.3e-203 L COG3385 FOG Transposase and inactivated derivatives
JHMANCOO_01518 1.3e-194 C FAD binding domain
JHMANCOO_01519 1.3e-86 P Major Facilitator Superfamily
JHMANCOO_01520 1.2e-41 K Bacterial regulatory helix-turn-helix protein, lysR family
JHMANCOO_01521 5.2e-41 L Transposase
JHMANCOO_01522 3.5e-153 L Transposase
JHMANCOO_01523 1.2e-227 L COG3547 Transposase and inactivated derivatives
JHMANCOO_01524 2e-183 scrR K helix_turn _helix lactose operon repressor
JHMANCOO_01525 1.1e-294 scrB 3.2.1.26 GH32 G invertase
JHMANCOO_01526 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
JHMANCOO_01527 2.6e-180 M CHAP domain
JHMANCOO_01528 2e-34
JHMANCOO_01529 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JHMANCOO_01530 2.6e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JHMANCOO_01531 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JHMANCOO_01532 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JHMANCOO_01533 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JHMANCOO_01534 6.7e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JHMANCOO_01535 9.6e-41 yajC U Preprotein translocase
JHMANCOO_01536 5.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JHMANCOO_01537 7.3e-211 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JHMANCOO_01538 4.7e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
JHMANCOO_01539 4.7e-228 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JHMANCOO_01540 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JHMANCOO_01541 2e-42 yrzL S Belongs to the UPF0297 family
JHMANCOO_01542 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JHMANCOO_01543 1.1e-50 yrzB S Belongs to the UPF0473 family
JHMANCOO_01544 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JHMANCOO_01545 3.5e-54 trxA O Belongs to the thioredoxin family
JHMANCOO_01546 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JHMANCOO_01547 1.1e-71 yslB S Protein of unknown function (DUF2507)
JHMANCOO_01548 1.7e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JHMANCOO_01549 1.6e-114 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JHMANCOO_01550 9.3e-130 S PAS domain
JHMANCOO_01551 7.6e-278 V ABC transporter transmembrane region
JHMANCOO_01552 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
JHMANCOO_01553 3.6e-126 T Transcriptional regulatory protein, C terminal
JHMANCOO_01554 2.8e-185 T GHKL domain
JHMANCOO_01555 9.8e-76 S Peptidase propeptide and YPEB domain
JHMANCOO_01556 8.8e-73 S Peptidase propeptide and YPEB domain
JHMANCOO_01557 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
JHMANCOO_01558 3.2e-64 yybA 2.3.1.57 K Transcriptional regulator
JHMANCOO_01559 5.8e-241 V ABC transporter transmembrane region
JHMANCOO_01560 3.1e-295 E ABC transporter, substratebinding protein
JHMANCOO_01561 7e-54 ypaA S Protein of unknown function (DUF1304)
JHMANCOO_01562 1e-57 S Peptidase propeptide and YPEB domain
JHMANCOO_01563 2.5e-212 V ABC transporter transmembrane region
JHMANCOO_01564 1.9e-46
JHMANCOO_01565 3.5e-100 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JHMANCOO_01566 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
JHMANCOO_01567 4.9e-99 E GDSL-like Lipase/Acylhydrolase
JHMANCOO_01568 1.7e-73 yjcF S Acetyltransferase (GNAT) domain
JHMANCOO_01569 2.8e-143 aatB ET ABC transporter substrate-binding protein
JHMANCOO_01570 1.6e-106 glnQ 3.6.3.21 E ABC transporter
JHMANCOO_01571 3.2e-110 glnP P ABC transporter permease
JHMANCOO_01572 0.0 helD 3.6.4.12 L DNA helicase
JHMANCOO_01573 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
JHMANCOO_01574 1.4e-126 pgm3 G Phosphoglycerate mutase family
JHMANCOO_01575 1.2e-241 S response to antibiotic
JHMANCOO_01576 5.4e-124
JHMANCOO_01577 0.0 3.6.3.8 P P-type ATPase
JHMANCOO_01578 8.7e-66 2.7.1.191 G PTS system fructose IIA component
JHMANCOO_01579 4.3e-43
JHMANCOO_01580 1.2e-227 L COG3547 Transposase and inactivated derivatives
JHMANCOO_01581 7.7e-09
JHMANCOO_01582 4.2e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
JHMANCOO_01583 1.6e-135 glvR K Helix-turn-helix domain, rpiR family
JHMANCOO_01584 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
JHMANCOO_01585 1.8e-153
JHMANCOO_01586 8.4e-24
JHMANCOO_01587 6.2e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JHMANCOO_01588 2e-157 S Archaea bacterial proteins of unknown function
JHMANCOO_01589 6.5e-107 3.2.2.20 K acetyltransferase
JHMANCOO_01591 0.0 O Belongs to the peptidase S8 family
JHMANCOO_01592 7.5e-53
JHMANCOO_01594 2.8e-09 S RelB antitoxin
JHMANCOO_01595 1.2e-12
JHMANCOO_01596 2.2e-36 S HicB_like antitoxin of bacterial toxin-antitoxin system
JHMANCOO_01598 1.3e-19 hicB S protein encoded in hypervariable junctions of pilus gene clusters
JHMANCOO_01601 1.3e-119 rfbP M Bacterial sugar transferase
JHMANCOO_01602 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
JHMANCOO_01603 3.7e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
JHMANCOO_01604 1.8e-143 epsB M biosynthesis protein
JHMANCOO_01605 1.5e-178 brpA K Cell envelope-like function transcriptional attenuator common domain protein
JHMANCOO_01606 1.3e-47 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
JHMANCOO_01607 1.3e-41 relB L RelB antitoxin
JHMANCOO_01609 1.8e-221 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JHMANCOO_01610 1.3e-174 S Cysteine-rich secretory protein family
JHMANCOO_01611 2.3e-40
JHMANCOO_01612 3.4e-118 M NlpC/P60 family
JHMANCOO_01613 3.9e-136 M NlpC P60 family protein
JHMANCOO_01614 3.4e-76 M NlpC/P60 family
JHMANCOO_01615 1.6e-94 gmk2 2.7.4.8 F Guanylate kinase homologues.
JHMANCOO_01616 9.3e-44
JHMANCOO_01617 2.9e-279 S O-antigen ligase like membrane protein
JHMANCOO_01618 3.3e-112
JHMANCOO_01619 1.9e-77 nrdI F NrdI Flavodoxin like
JHMANCOO_01620 1.8e-178 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHMANCOO_01621 2.5e-68
JHMANCOO_01622 9.3e-135 yvpB S Peptidase_C39 like family
JHMANCOO_01623 8.7e-84 S Threonine/Serine exporter, ThrE
JHMANCOO_01624 4.8e-137 thrE S Putative threonine/serine exporter
JHMANCOO_01625 1.7e-290 S ABC transporter
JHMANCOO_01626 2.5e-62
JHMANCOO_01627 2.2e-102 rimL J Acetyltransferase (GNAT) domain
JHMANCOO_01628 1.1e-95
JHMANCOO_01629 6.5e-125 S Protein of unknown function (DUF554)
JHMANCOO_01630 9.6e-204 brpA K Cell envelope-like function transcriptional attenuator common domain protein
JHMANCOO_01631 0.0 pepF E oligoendopeptidase F
JHMANCOO_01632 3e-13 Z012_06740 S Fic/DOC family
JHMANCOO_01633 2.9e-31
JHMANCOO_01634 4.6e-70 doc S Prophage maintenance system killer protein
JHMANCOO_01635 3e-212 2.1.1.14 E methionine synthase, vitamin-B12 independent
JHMANCOO_01636 6.1e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JHMANCOO_01637 1.9e-262 lctP C L-lactate permease
JHMANCOO_01638 8.5e-129 znuB U ABC 3 transport family
JHMANCOO_01639 3e-116 fhuC P ABC transporter
JHMANCOO_01640 1.4e-148 psaA P Belongs to the bacterial solute-binding protein 9 family
JHMANCOO_01641 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
JHMANCOO_01642 8.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
JHMANCOO_01643 4.4e-135 fruR K DeoR C terminal sensor domain
JHMANCOO_01644 4.3e-217 natB CP ABC-2 family transporter protein
JHMANCOO_01645 1.2e-163 natA S ABC transporter, ATP-binding protein
JHMANCOO_01646 1.5e-68
JHMANCOO_01647 2.4e-24
JHMANCOO_01648 8.2e-31 yozG K Transcriptional regulator
JHMANCOO_01649 8.4e-80
JHMANCOO_01650 1.8e-21
JHMANCOO_01652 1.6e-39
JHMANCOO_01653 2.4e-63
JHMANCOO_01654 1.9e-30
JHMANCOO_01655 5.6e-144 K LytTr DNA-binding domain
JHMANCOO_01656 7.3e-121 2.7.13.3 T GHKL domain
JHMANCOO_01657 5e-18
JHMANCOO_01658 2.5e-147 ykuT M mechanosensitive ion channel
JHMANCOO_01659 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JHMANCOO_01660 1.3e-36
JHMANCOO_01661 2.2e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
JHMANCOO_01662 4.9e-182 ccpA K catabolite control protein A
JHMANCOO_01663 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JHMANCOO_01664 4.3e-55
JHMANCOO_01665 1.2e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JHMANCOO_01666 1.7e-105 yutD S Protein of unknown function (DUF1027)
JHMANCOO_01667 6.9e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JHMANCOO_01668 3.7e-100 S Protein of unknown function (DUF1461)
JHMANCOO_01669 2.3e-116 dedA S SNARE-like domain protein
JHMANCOO_01670 8e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
JHMANCOO_01672 5.7e-209 S CAAX protease self-immunity
JHMANCOO_01673 1.6e-219 S CAAX protease self-immunity
JHMANCOO_01675 1.2e-67
JHMANCOO_01676 6.4e-11
JHMANCOO_01677 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
JHMANCOO_01678 7.9e-271 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
JHMANCOO_01679 3e-24
JHMANCOO_01680 9.5e-26
JHMANCOO_01681 2.5e-33
JHMANCOO_01682 6.2e-54 S Enterocin A Immunity
JHMANCOO_01683 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
JHMANCOO_01684 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JHMANCOO_01685 1.3e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
JHMANCOO_01686 1.6e-120 K response regulator
JHMANCOO_01687 3.9e-39 S HicB family
JHMANCOO_01688 1.1e-204 L Probable transposase
JHMANCOO_01690 0.0 V ABC transporter
JHMANCOO_01691 5.1e-304 V ABC transporter, ATP-binding protein
JHMANCOO_01692 1.4e-136 XK27_01040 S Protein of unknown function (DUF1129)
JHMANCOO_01693 6.1e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JHMANCOO_01694 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
JHMANCOO_01695 6.5e-154 spo0J K Belongs to the ParB family
JHMANCOO_01696 3.4e-138 soj D Sporulation initiation inhibitor
JHMANCOO_01697 5e-148 noc K Belongs to the ParB family
JHMANCOO_01698 3.1e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
JHMANCOO_01699 3e-53 cvpA S Colicin V production protein
JHMANCOO_01701 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JHMANCOO_01702 4.3e-149 3.1.3.48 T Tyrosine phosphatase family
JHMANCOO_01703 1.7e-96 azr 1.5.1.36 S NADPH-dependent FMN reductase
JHMANCOO_01704 2.4e-95 nqr 1.5.1.36 S NADPH-dependent FMN reductase
JHMANCOO_01705 1.8e-110 K WHG domain
JHMANCOO_01706 8e-38
JHMANCOO_01707 3.4e-274 pipD E Dipeptidase
JHMANCOO_01708 5.2e-156 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
JHMANCOO_01709 2e-155 metC1 4.4.1.8 E cystathionine
JHMANCOO_01710 4.4e-99 metQ1 P Belongs to the nlpA lipoprotein family
JHMANCOO_01711 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
JHMANCOO_01712 2.7e-170 hrtB V ABC transporter permease
JHMANCOO_01713 3.1e-95 ygfC K Bacterial regulatory proteins, tetR family
JHMANCOO_01714 7.1e-112 G phosphoglycerate mutase
JHMANCOO_01715 4.9e-142 aroD S Alpha/beta hydrolase family
JHMANCOO_01716 4.4e-143 S Belongs to the UPF0246 family
JHMANCOO_01717 9e-121
JHMANCOO_01718 8.7e-158 2.7.7.12 C Domain of unknown function (DUF4931)
JHMANCOO_01719 2.6e-190 S Putative peptidoglycan binding domain
JHMANCOO_01720 4e-16
JHMANCOO_01721 1.8e-91 liaI S membrane
JHMANCOO_01722 6e-71 XK27_02470 K LytTr DNA-binding domain
JHMANCOO_01723 8.8e-19 S Sugar efflux transporter for intercellular exchange
JHMANCOO_01724 1.1e-249 dtpT U amino acid peptide transporter
JHMANCOO_01725 0.0 pepN 3.4.11.2 E aminopeptidase
JHMANCOO_01726 2.8e-47 lysM M LysM domain
JHMANCOO_01727 5.1e-176
JHMANCOO_01728 3.9e-213 mdtG EGP Major facilitator Superfamily
JHMANCOO_01729 1.9e-89 ymdB S Macro domain protein
JHMANCOO_01730 2e-08
JHMANCOO_01732 3.3e-147 malG P ABC transporter permease
JHMANCOO_01733 3.3e-250 malF P Binding-protein-dependent transport system inner membrane component
JHMANCOO_01734 1.3e-213 malE G Bacterial extracellular solute-binding protein
JHMANCOO_01735 4.7e-210 msmX P Belongs to the ABC transporter superfamily
JHMANCOO_01736 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
JHMANCOO_01737 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
JHMANCOO_01738 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
JHMANCOO_01739 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
JHMANCOO_01740 4.8e-78 S PAS domain
JHMANCOO_01741 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHMANCOO_01742 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
JHMANCOO_01743 1.4e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
JHMANCOO_01744 1.7e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JHMANCOO_01745 9.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JHMANCOO_01746 6.7e-85
JHMANCOO_01747 3.3e-20
JHMANCOO_01748 1.3e-143 K Helix-turn-helix XRE-family like proteins
JHMANCOO_01749 5.9e-47 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
JHMANCOO_01750 8.5e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
JHMANCOO_01751 1.4e-15 G Transmembrane secretion effector
JHMANCOO_01752 1.5e-68 L RelB antitoxin
JHMANCOO_01754 2.1e-131 cobQ S glutamine amidotransferase
JHMANCOO_01755 2.4e-81 M NlpC/P60 family
JHMANCOO_01758 4.3e-35
JHMANCOO_01759 3.9e-165 EG EamA-like transporter family
JHMANCOO_01760 1.6e-166 EG EamA-like transporter family
JHMANCOO_01761 1.8e-30 yicL EG EamA-like transporter family
JHMANCOO_01762 1.8e-78 yicL EG EamA-like transporter family
JHMANCOO_01763 2.5e-107
JHMANCOO_01764 1.1e-110
JHMANCOO_01765 5.8e-186 XK27_05540 S DUF218 domain
JHMANCOO_01766 1.6e-263 yheS_2 S ATPases associated with a variety of cellular activities
JHMANCOO_01767 1.6e-88
JHMANCOO_01768 3.9e-57
JHMANCOO_01769 3.3e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JHMANCOO_01770 1.4e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JHMANCOO_01771 7e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JHMANCOO_01774 8.2e-204 4.2.1.126 S Bacterial protein of unknown function (DUF871)
JHMANCOO_01775 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
JHMANCOO_01776 3.3e-229 steT_1 E amino acid
JHMANCOO_01777 3.7e-139 puuD S peptidase C26
JHMANCOO_01779 1.3e-122 V HNH endonuclease
JHMANCOO_01780 1.2e-23 V HNH endonuclease
JHMANCOO_01781 1.4e-134 S PFAM Archaeal ATPase
JHMANCOO_01782 6.2e-244 yifK E Amino acid permease
JHMANCOO_01783 6.3e-233 cycA E Amino acid permease
JHMANCOO_01784 2.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JHMANCOO_01785 0.0 clpE O AAA domain (Cdc48 subfamily)
JHMANCOO_01786 4.4e-166 S Alpha/beta hydrolase of unknown function (DUF915)
JHMANCOO_01787 7.4e-239 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JHMANCOO_01788 1.6e-123 XK27_06785 V ABC transporter, ATP-binding protein
JHMANCOO_01789 0.0 XK27_06780 V ABC transporter permease
JHMANCOO_01790 5.6e-36
JHMANCOO_01791 6.7e-290 ytgP S Polysaccharide biosynthesis protein
JHMANCOO_01792 2.7e-137 lysA2 M Glycosyl hydrolases family 25
JHMANCOO_01793 1.3e-116 S Protein of unknown function (DUF975)
JHMANCOO_01795 1.3e-168 pbpX2 V Beta-lactamase
JHMANCOO_01796 3.4e-244 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JHMANCOO_01797 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHMANCOO_01798 1.7e-237 dltB M MBOAT, membrane-bound O-acyltransferase family
JHMANCOO_01799 1.3e-287 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JHMANCOO_01800 5.2e-19 S D-Ala-teichoic acid biosynthesis protein
JHMANCOO_01801 1.9e-47
JHMANCOO_01802 5.3e-217 ywhK S Membrane
JHMANCOO_01803 3.9e-81 ykuL S (CBS) domain
JHMANCOO_01804 0.0 cadA P P-type ATPase
JHMANCOO_01805 5.7e-206 napA P Sodium/hydrogen exchanger family
JHMANCOO_01806 3.2e-281 V ABC transporter transmembrane region
JHMANCOO_01807 8.8e-73 S Putative adhesin
JHMANCOO_01808 1.4e-156 mutR K Helix-turn-helix XRE-family like proteins
JHMANCOO_01809 6.4e-52
JHMANCOO_01810 3.4e-156 EGP Major facilitator Superfamily
JHMANCOO_01811 8.7e-111 ropB K Transcriptional regulator
JHMANCOO_01812 8.3e-122 S CAAX protease self-immunity
JHMANCOO_01813 9.5e-195 S DUF218 domain
JHMANCOO_01814 0.0 macB_3 V ABC transporter, ATP-binding protein
JHMANCOO_01815 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JHMANCOO_01816 3.3e-101 S ECF transporter, substrate-specific component
JHMANCOO_01817 4.7e-202 tcsA S ABC transporter substrate-binding protein PnrA-like
JHMANCOO_01818 1.5e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
JHMANCOO_01819 5.2e-284 xylG 3.6.3.17 S ABC transporter
JHMANCOO_01820 9.6e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
JHMANCOO_01821 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
JHMANCOO_01822 4.3e-160 yeaE S Aldo/keto reductase family
JHMANCOO_01823 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JHMANCOO_01824 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
JHMANCOO_01825 9e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
JHMANCOO_01826 3.1e-67
JHMANCOO_01827 5.7e-141 cof S haloacid dehalogenase-like hydrolase
JHMANCOO_01828 2.2e-230 pbuG S permease
JHMANCOO_01829 5.6e-225 S cog cog1373
JHMANCOO_01830 1.5e-127 K helix_turn_helix, mercury resistance
JHMANCOO_01831 3e-232 pbuG S permease
JHMANCOO_01832 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
JHMANCOO_01833 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
JHMANCOO_01834 2e-47 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
JHMANCOO_01835 2.3e-41 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
JHMANCOO_01836 3e-94 K Transcriptional regulator
JHMANCOO_01837 2.8e-61 K Transcriptional regulator
JHMANCOO_01838 6.9e-223 S cog cog1373
JHMANCOO_01839 1.6e-135 S haloacid dehalogenase-like hydrolase
JHMANCOO_01840 1.6e-225 pbuG S permease
JHMANCOO_01841 1.4e-29
JHMANCOO_01842 5.1e-75 atkY K Penicillinase repressor
JHMANCOO_01843 3.1e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
JHMANCOO_01844 7e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
JHMANCOO_01845 0.0 copA 3.6.3.54 P P-type ATPase
JHMANCOO_01846 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
JHMANCOO_01847 3.5e-105
JHMANCOO_01848 1.6e-247 EGP Sugar (and other) transporter
JHMANCOO_01849 1.2e-18
JHMANCOO_01850 1.5e-211
JHMANCOO_01851 1.4e-289 clcA P chloride
JHMANCOO_01852 2.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JHMANCOO_01853 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JHMANCOO_01854 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JHMANCOO_01855 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JHMANCOO_01856 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JHMANCOO_01857 2.3e-60 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JHMANCOO_01858 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
JHMANCOO_01859 5.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JHMANCOO_01860 1.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JHMANCOO_01861 2.6e-35 yaaA S S4 domain protein YaaA
JHMANCOO_01862 5.3e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JHMANCOO_01863 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JHMANCOO_01864 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JHMANCOO_01865 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
JHMANCOO_01866 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JHMANCOO_01867 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JHMANCOO_01868 3.7e-108 S Bacteriocin helveticin-J
JHMANCOO_01869 3.4e-200 S SLAP domain
JHMANCOO_01870 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JHMANCOO_01871 5.7e-69 rplI J Binds to the 23S rRNA
JHMANCOO_01872 7.4e-253 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JHMANCOO_01873 9.2e-167 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
JHMANCOO_01874 4.6e-166 degV S DegV family
JHMANCOO_01875 2.7e-168 scrK 2.7.1.2, 2.7.1.4 GK ROK family
JHMANCOO_01877 2.4e-16
JHMANCOO_01878 8.3e-232 I Protein of unknown function (DUF2974)
JHMANCOO_01879 1.1e-119 yhiD S MgtC family
JHMANCOO_01881 2.2e-28
JHMANCOO_01882 1.4e-06 S LPXTG cell wall anchor motif
JHMANCOO_01883 4.4e-146 S Putative ABC-transporter type IV
JHMANCOO_01884 5.1e-80 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
JHMANCOO_01885 4.3e-43 M domain protein
JHMANCOO_01887 4.2e-273 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JHMANCOO_01888 2.3e-117 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
JHMANCOO_01889 4.1e-37 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
JHMANCOO_01890 0.0 oppA E ABC transporter substrate-binding protein
JHMANCOO_01891 1.4e-176 K AI-2E family transporter
JHMANCOO_01892 3.1e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
JHMANCOO_01893 6.9e-18
JHMANCOO_01894 2e-247 G Major Facilitator
JHMANCOO_01895 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
JHMANCOO_01896 3.6e-120 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
JHMANCOO_01897 6.8e-176 ABC-SBP S ABC transporter
JHMANCOO_01898 1.1e-135 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
JHMANCOO_01899 5.5e-87
JHMANCOO_01900 2.7e-74 M LysM domain
JHMANCOO_01902 2.7e-49
JHMANCOO_01903 1.9e-10
JHMANCOO_01904 1.4e-44 lrp QT PucR C-terminal helix-turn-helix domain
JHMANCOO_01905 2.4e-185 msmX P Belongs to the ABC transporter superfamily
JHMANCOO_01906 1e-152 G Alpha galactosidase A
JHMANCOO_01907 1.1e-133 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JHMANCOO_01908 1.2e-224 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
JHMANCOO_01909 7.7e-121 abf2 G Glycosyl hydrolases family 43
JHMANCOO_01911 7e-113 araQ_3 G Binding-protein-dependent transport system inner membrane component
JHMANCOO_01912 4.7e-123 araP P ABC-type sugar transport systems, permease components
JHMANCOO_01913 6.5e-129 araN G Arabinose-binding protein
JHMANCOO_01915 3.5e-199 L Transposase and inactivated derivatives, IS30 family
JHMANCOO_01916 9.8e-109 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
JHMANCOO_01918 5.8e-68 D ftsk spoiiie
JHMANCOO_01922 5.5e-53 adhR K helix_turn_helix, mercury resistance
JHMANCOO_01923 9.6e-46 tas 1.1.1.65 C Aldo keto reductase
JHMANCOO_01924 7.2e-62 tas 1.1.1.65 C Aldo keto reductase
JHMANCOO_01925 1.7e-47 S Uncharacterized protein conserved in bacteria (DUF2255)
JHMANCOO_01926 9.7e-121 4.1.1.45 S Amidohydrolase
JHMANCOO_01927 2.9e-73 lacA 2.3.1.79 S Maltose acetyltransferase
JHMANCOO_01928 7.2e-206 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
JHMANCOO_01929 1.1e-149 3.2.1.99 GH43 M C-terminal of Glycosyl hydrolases family 43
JHMANCOO_01930 1e-220 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
JHMANCOO_01931 3.1e-251 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
JHMANCOO_01932 2.4e-47 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
JHMANCOO_01933 1.2e-130 araR K Transcriptional regulator
JHMANCOO_01934 5.4e-122 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
JHMANCOO_01935 2e-225 araB 2.7.1.16 G carbohydrate kinase FGGY
JHMANCOO_01936 3.9e-154 EGP Major Facilitator Superfamily
JHMANCOO_01937 9.9e-25 K LysR substrate binding domain
JHMANCOO_01938 5.5e-82 C FAD dependent oxidoreductase
JHMANCOO_01939 4e-148 P transporter
JHMANCOO_01940 1.7e-267 1.3.5.4 C FAD binding domain
JHMANCOO_01941 3.3e-113 ydiN G Major Facilitator Superfamily
JHMANCOO_01942 6.9e-106 K Transcriptional regulator, LysR family
JHMANCOO_01943 8.2e-160 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JHMANCOO_01944 4.9e-110 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JHMANCOO_01945 3.5e-30 S PFAM Archaeal ATPase
JHMANCOO_01946 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
JHMANCOO_01947 1.3e-42 S Protein of unknown function DUF262
JHMANCOO_01948 1.5e-07 S Protein of unknown function DUF262
JHMANCOO_01949 8.1e-21 S Membrane

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)