ORF_ID e_value Gene_name EC_number CAZy COGs Description
MKGHLHII_00001 3.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKGHLHII_00002 9.5e-31
MKGHLHII_00003 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MKGHLHII_00004 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MKGHLHII_00005 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MKGHLHII_00006 3.5e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKGHLHII_00007 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MKGHLHII_00008 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MKGHLHII_00009 1.6e-244 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MKGHLHII_00010 3.6e-181 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MKGHLHII_00011 2.6e-35 yaaA S S4 domain protein YaaA
MKGHLHII_00012 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKGHLHII_00013 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKGHLHII_00014 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKGHLHII_00015 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
MKGHLHII_00016 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MKGHLHII_00017 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MKGHLHII_00019 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MKGHLHII_00020 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
MKGHLHII_00021 1.4e-36 S Cytochrome B5
MKGHLHII_00022 6e-168 arbZ I Phosphate acyltransferases
MKGHLHII_00023 1.6e-182 arbY M Glycosyl transferase family 8
MKGHLHII_00024 5e-184 arbY M Glycosyl transferase family 8
MKGHLHII_00025 5e-156 arbx M Glycosyl transferase family 8
MKGHLHII_00026 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
MKGHLHII_00028 4.9e-34
MKGHLHII_00030 4.8e-131 K response regulator
MKGHLHII_00031 2.2e-305 vicK 2.7.13.3 T Histidine kinase
MKGHLHII_00032 1.6e-257 yycH S YycH protein
MKGHLHII_00033 3.4e-149 yycI S YycH protein
MKGHLHII_00034 4.1e-147 vicX 3.1.26.11 S domain protein
MKGHLHII_00035 1.2e-153 htrA 3.4.21.107 O serine protease
MKGHLHII_00037 2e-57 clcA P chloride
MKGHLHII_00038 3.9e-113 L PFAM Integrase catalytic
MKGHLHII_00039 1.3e-284 lsa S ABC transporter
MKGHLHII_00040 2.4e-44
MKGHLHII_00041 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MKGHLHII_00042 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MKGHLHII_00043 9.7e-52 S Iron-sulfur cluster assembly protein
MKGHLHII_00044 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MKGHLHII_00045 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MKGHLHII_00046 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MKGHLHII_00047 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKGHLHII_00048 3.3e-275 yjeM E Amino Acid
MKGHLHII_00049 5.8e-83 S Fic/DOC family
MKGHLHII_00050 3.1e-278
MKGHLHII_00051 3.2e-77
MKGHLHII_00052 2.3e-87 S Protein of unknown function (DUF805)
MKGHLHII_00053 5.6e-68 O OsmC-like protein
MKGHLHII_00054 9.4e-209 EGP Major facilitator Superfamily
MKGHLHII_00055 2.5e-215 sptS 2.7.13.3 T Histidine kinase
MKGHLHII_00056 6.4e-24 K response regulator
MKGHLHII_00057 6.4e-71 scrR K Periplasmic binding protein domain
MKGHLHII_00058 5.5e-36
MKGHLHII_00059 2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MKGHLHII_00060 1.1e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MKGHLHII_00061 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MKGHLHII_00062 0.0 lacZ 3.2.1.23 G -beta-galactosidase
MKGHLHII_00063 0.0 lacS G Transporter
MKGHLHII_00064 3.2e-165 lacR K Transcriptional regulator
MKGHLHII_00065 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MKGHLHII_00066 3e-144 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MKGHLHII_00067 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MKGHLHII_00068 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
MKGHLHII_00069 2e-106 K Transcriptional regulator, AbiEi antitoxin
MKGHLHII_00070 1.2e-188 K Periplasmic binding protein-like domain
MKGHLHII_00071 3.7e-228 L COG2963 Transposase and inactivated derivatives
MKGHLHII_00072 4.3e-21
MKGHLHII_00073 6e-148
MKGHLHII_00074 6.7e-170
MKGHLHII_00075 2e-263 glnA 6.3.1.2 E glutamine synthetase
MKGHLHII_00076 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
MKGHLHII_00077 1.2e-166 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MKGHLHII_00078 1.5e-65 yqhL P Rhodanese-like protein
MKGHLHII_00079 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
MKGHLHII_00080 4e-119 gluP 3.4.21.105 S Rhomboid family
MKGHLHII_00081 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKGHLHII_00082 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MKGHLHII_00083 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MKGHLHII_00084 0.0 S membrane
MKGHLHII_00085 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
MKGHLHII_00086 1.3e-38 S RelB antitoxin
MKGHLHII_00087 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
MKGHLHII_00088 5.7e-43 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKGHLHII_00089 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
MKGHLHII_00090 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKGHLHII_00091 8.7e-159 isdE P Periplasmic binding protein
MKGHLHII_00092 6.3e-123 M Iron Transport-associated domain
MKGHLHII_00093 3e-09 isdH M Iron Transport-associated domain
MKGHLHII_00094 2.2e-89
MKGHLHII_00095 2.2e-113 S SLAP domain
MKGHLHII_00096 2.6e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MKGHLHII_00097 5.7e-46 S An automated process has identified a potential problem with this gene model
MKGHLHII_00098 3e-137 S Protein of unknown function (DUF3100)
MKGHLHII_00099 4e-245 3.5.1.47 S Peptidase dimerisation domain
MKGHLHII_00100 5.8e-230 Q Imidazolonepropionase and related amidohydrolases
MKGHLHII_00101 0.0 oppA E ABC transporter
MKGHLHII_00102 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
MKGHLHII_00103 0.0 mco Q Multicopper oxidase
MKGHLHII_00104 1.9e-25
MKGHLHII_00105 1.9e-158 metQ1 P Belongs to the nlpA lipoprotein family
MKGHLHII_00106 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
MKGHLHII_00107 2.4e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKGHLHII_00108 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKGHLHII_00109 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MKGHLHII_00110 8.1e-91 cjaA ET ABC transporter substrate-binding protein
MKGHLHII_00111 3e-53 cjaA ET ABC transporter substrate-binding protein
MKGHLHII_00112 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MKGHLHII_00113 2e-110 P ABC transporter permease
MKGHLHII_00114 9.6e-110 papP P ABC transporter, permease protein
MKGHLHII_00116 8.8e-62 yodB K Transcriptional regulator, HxlR family
MKGHLHII_00117 5e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKGHLHII_00118 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MKGHLHII_00119 2.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKGHLHII_00120 1.5e-72 S Aminoacyl-tRNA editing domain
MKGHLHII_00121 1.2e-54 S Abi-like protein
MKGHLHII_00122 8e-224 S SLAP domain
MKGHLHII_00123 3.9e-128 S CAAX protease self-immunity
MKGHLHII_00124 8.4e-25 G Peptidase_C39 like family
MKGHLHII_00125 2.8e-162 M NlpC/P60 family
MKGHLHII_00126 6.5e-91 G Peptidase_C39 like family
MKGHLHII_00127 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
MKGHLHII_00128 2.8e-77 P Cobalt transport protein
MKGHLHII_00129 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
MKGHLHII_00130 7.9e-174 K helix_turn_helix, arabinose operon control protein
MKGHLHII_00131 8.3e-157 htpX O Belongs to the peptidase M48B family
MKGHLHII_00132 5.1e-96 lemA S LemA family
MKGHLHII_00133 6.7e-168 ybiR P Citrate transporter
MKGHLHII_00135 2e-70 S Iron-sulphur cluster biosynthesis
MKGHLHII_00136 1.2e-308 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
MKGHLHII_00137 1.2e-17
MKGHLHII_00138 1.1e-07 S Uncharacterised protein family (UPF0236)
MKGHLHII_00139 4.5e-189 ydaM M Glycosyl transferase
MKGHLHII_00140 4e-177 G Glycosyl hydrolases family 8
MKGHLHII_00141 1e-119 yfbR S HD containing hydrolase-like enzyme
MKGHLHII_00142 6.4e-159 L HNH nucleases
MKGHLHII_00143 1.3e-277 arlS 2.7.13.3 T Histidine kinase
MKGHLHII_00144 1.2e-126 K response regulator
MKGHLHII_00145 4.7e-97 yceD S Uncharacterized ACR, COG1399
MKGHLHII_00146 1.7e-215 ylbM S Belongs to the UPF0348 family
MKGHLHII_00147 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MKGHLHII_00148 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MKGHLHII_00149 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MKGHLHII_00150 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
MKGHLHII_00151 4.2e-84 yqeG S HAD phosphatase, family IIIA
MKGHLHII_00152 9.2e-201 tnpB L Putative transposase DNA-binding domain
MKGHLHII_00153 6.9e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MKGHLHII_00154 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MKGHLHII_00155 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MKGHLHII_00156 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MKGHLHII_00157 4e-98 rihB 3.2.2.1 F Nucleoside
MKGHLHII_00158 2.9e-38 potB E Binding-protein-dependent transport system inner membrane component
MKGHLHII_00159 3e-107 L Transposase
MKGHLHII_00160 1.3e-96 L Transposase
MKGHLHII_00161 1.5e-180 S Domain of unknown function (DUF389)
MKGHLHII_00162 1.4e-124 L Transposase and inactivated derivatives, IS30 family
MKGHLHII_00163 4.3e-75
MKGHLHII_00164 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKGHLHII_00165 1.3e-168 dnaI L Primosomal protein DnaI
MKGHLHII_00166 5.1e-251 dnaB L Replication initiation and membrane attachment
MKGHLHII_00167 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MKGHLHII_00168 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MKGHLHII_00169 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MKGHLHII_00170 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKGHLHII_00171 3.5e-25 qmcA O prohibitin homologues
MKGHLHII_00172 7.4e-105 qmcA O prohibitin homologues
MKGHLHII_00173 8e-51 L RelB antitoxin
MKGHLHII_00174 4.5e-188 S Bacteriocin helveticin-J
MKGHLHII_00175 4.4e-283 M Peptidase family M1 domain
MKGHLHII_00176 1.8e-176 S SLAP domain
MKGHLHII_00177 6.9e-218 mepA V MATE efflux family protein
MKGHLHII_00178 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MKGHLHII_00179 1.7e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKGHLHII_00180 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MKGHLHII_00182 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MKGHLHII_00183 2.7e-219 ecsB U ABC transporter
MKGHLHII_00184 5.7e-135 ecsA V ABC transporter, ATP-binding protein
MKGHLHII_00185 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
MKGHLHII_00186 3.9e-25
MKGHLHII_00187 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MKGHLHII_00188 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
MKGHLHII_00189 1.1e-265
MKGHLHII_00190 3.9e-31 S Domain of unknown function DUF1829
MKGHLHII_00191 2.9e-23
MKGHLHII_00192 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
MKGHLHII_00193 0.0 L AAA domain
MKGHLHII_00194 1e-226 yhaO L Ser Thr phosphatase family protein
MKGHLHII_00195 7.2e-56 yheA S Belongs to the UPF0342 family
MKGHLHII_00196 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MKGHLHII_00197 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MKGHLHII_00198 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MKGHLHII_00199 7.5e-103 G Phosphoglycerate mutase family
MKGHLHII_00200 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MKGHLHII_00202 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MKGHLHII_00203 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
MKGHLHII_00204 5.6e-179 S PFAM Archaeal ATPase
MKGHLHII_00205 2.4e-73 S cog cog1373
MKGHLHII_00206 2.4e-128 S cog cog1373
MKGHLHII_00207 1.4e-109 yniG EGP Major facilitator Superfamily
MKGHLHII_00208 5.4e-237 L transposase, IS605 OrfB family
MKGHLHII_00209 4.5e-76 yniG EGP Major facilitator Superfamily
MKGHLHII_00210 4.9e-35
MKGHLHII_00212 1.3e-42
MKGHLHII_00213 1.9e-75 M LysM domain
MKGHLHII_00214 1e-20 S Enterocin A Immunity
MKGHLHII_00216 5.7e-43 2.4.1.33 V HlyD family secretion protein
MKGHLHII_00217 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MKGHLHII_00218 2.9e-79 K LytTr DNA-binding domain
MKGHLHII_00219 2.1e-78 2.7.13.3 T GHKL domain
MKGHLHII_00220 1.1e-71 2.5.1.74 H UbiA prenyltransferase family
MKGHLHII_00221 7.7e-26
MKGHLHII_00222 5.7e-84 S PFAM Archaeal ATPase
MKGHLHII_00223 2.2e-85 S PFAM Archaeal ATPase
MKGHLHII_00224 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MKGHLHII_00225 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MKGHLHII_00226 6.7e-98 M ErfK YbiS YcfS YnhG
MKGHLHII_00227 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MKGHLHII_00228 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MKGHLHII_00230 4.7e-46 pspC KT PspC domain
MKGHLHII_00231 3.3e-237 L COG2963 Transposase and inactivated derivatives
MKGHLHII_00232 7.3e-148 S Protein of unknown function (DUF805)
MKGHLHII_00233 3.4e-135 glnQ E ABC transporter, ATP-binding protein
MKGHLHII_00234 6.7e-290 glnP P ABC transporter permease
MKGHLHII_00235 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MKGHLHII_00236 5.8e-64 yeaO S Protein of unknown function, DUF488
MKGHLHII_00237 1.3e-124 terC P Integral membrane protein TerC family
MKGHLHII_00238 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
MKGHLHII_00239 8.5e-133 cobB K SIR2 family
MKGHLHII_00240 1.1e-282 phoR 2.7.13.3 T Histidine kinase
MKGHLHII_00241 1.2e-120 T Transcriptional regulatory protein, C terminal
MKGHLHII_00242 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
MKGHLHII_00243 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKGHLHII_00244 1.2e-152 pstA P Phosphate transport system permease protein PstA
MKGHLHII_00245 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
MKGHLHII_00246 4.2e-145 pstS P Phosphate
MKGHLHII_00247 1.3e-30
MKGHLHII_00248 6.3e-192 oppA E ABC transporter, substratebinding protein
MKGHLHII_00249 4.7e-275 ytgP S Polysaccharide biosynthesis protein
MKGHLHII_00250 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MKGHLHII_00251 1.1e-121 3.6.1.27 I Acid phosphatase homologues
MKGHLHII_00252 2.8e-168 K LysR substrate binding domain
MKGHLHII_00253 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MKGHLHII_00254 6.2e-43 1.3.5.4 C FAD binding domain
MKGHLHII_00255 2.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
MKGHLHII_00256 1.1e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MKGHLHII_00257 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MKGHLHII_00258 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MKGHLHII_00259 1.2e-268 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MKGHLHII_00260 1.6e-296 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MKGHLHII_00261 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MKGHLHII_00262 6.4e-243 cydA 1.10.3.14 C ubiquinol oxidase
MKGHLHII_00263 1.1e-48 ybbH_2 K rpiR family
MKGHLHII_00264 3.4e-195 S Bacterial protein of unknown function (DUF871)
MKGHLHII_00265 4.1e-214 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKGHLHII_00266 1.8e-119 S Putative esterase
MKGHLHII_00267 3.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MKGHLHII_00268 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
MKGHLHII_00270 8.5e-260 qacA EGP Major facilitator Superfamily
MKGHLHII_00271 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MKGHLHII_00274 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
MKGHLHII_00276 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
MKGHLHII_00277 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
MKGHLHII_00278 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
MKGHLHII_00279 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
MKGHLHII_00280 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKGHLHII_00281 7.5e-100 J Acetyltransferase (GNAT) domain
MKGHLHII_00282 1.4e-110 yjbF S SNARE associated Golgi protein
MKGHLHII_00283 6.7e-150 I alpha/beta hydrolase fold
MKGHLHII_00284 1.2e-62 hipB K Helix-turn-helix
MKGHLHII_00285 6e-85 hipB K Helix-turn-helix
MKGHLHII_00286 1.4e-15 S cog cog1373
MKGHLHII_00287 1e-30 S cog cog1373
MKGHLHII_00288 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
MKGHLHII_00289 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MKGHLHII_00290 6.1e-227 L COG3547 Transposase and inactivated derivatives
MKGHLHII_00291 1.8e-163
MKGHLHII_00292 7.8e-26 K Acetyltransferase (GNAT) domain
MKGHLHII_00294 0.0 ydgH S MMPL family
MKGHLHII_00295 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
MKGHLHII_00296 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
MKGHLHII_00297 1.8e-154 corA P CorA-like Mg2+ transporter protein
MKGHLHII_00298 6.7e-240 G Bacterial extracellular solute-binding protein
MKGHLHII_00299 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
MKGHLHII_00300 1.8e-145 gtsC P Binding-protein-dependent transport system inner membrane component
MKGHLHII_00301 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
MKGHLHII_00302 1.9e-203 malK P ATPases associated with a variety of cellular activities
MKGHLHII_00303 1.3e-281 pipD E Dipeptidase
MKGHLHII_00304 1.9e-158 endA F DNA RNA non-specific endonuclease
MKGHLHII_00305 8e-182 dnaQ 2.7.7.7 L EXOIII
MKGHLHII_00306 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MKGHLHII_00307 3e-116 yviA S Protein of unknown function (DUF421)
MKGHLHII_00308 1.1e-56 S Protein of unknown function (DUF3290)
MKGHLHII_00310 3.8e-139 pnuC H nicotinamide mononucleotide transporter
MKGHLHII_00311 1.3e-51
MKGHLHII_00312 2.7e-57
MKGHLHII_00313 1.6e-11
MKGHLHII_00314 8.1e-126 S PAS domain
MKGHLHII_00315 2.8e-14 L PFAM transposase, IS4 family protein
MKGHLHII_00316 9.3e-86
MKGHLHII_00317 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKGHLHII_00318 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
MKGHLHII_00319 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKGHLHII_00320 4.4e-140 ypuA S Protein of unknown function (DUF1002)
MKGHLHII_00321 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
MKGHLHII_00322 7.3e-126 S Alpha/beta hydrolase family
MKGHLHII_00323 2.9e-277 V ABC transporter transmembrane region
MKGHLHII_00324 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MKGHLHII_00325 3.1e-130 T Transcriptional regulatory protein, C terminal
MKGHLHII_00326 5.2e-187 T GHKL domain
MKGHLHII_00327 3.4e-76 S Peptidase propeptide and YPEB domain
MKGHLHII_00328 2.5e-72 S Peptidase propeptide and YPEB domain
MKGHLHII_00329 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MKGHLHII_00330 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
MKGHLHII_00331 7e-68 V ABC transporter transmembrane region
MKGHLHII_00332 9e-161 V ABC transporter transmembrane region
MKGHLHII_00333 2.3e-309 oppA3 E ABC transporter, substratebinding protein
MKGHLHII_00334 2.4e-60 ypaA S Protein of unknown function (DUF1304)
MKGHLHII_00335 2.1e-28 S Peptidase propeptide and YPEB domain
MKGHLHII_00336 7.1e-237 L transposase, IS605 OrfB family
MKGHLHII_00337 8.8e-58 S Peptidase propeptide and YPEB domain
MKGHLHII_00338 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKGHLHII_00339 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
MKGHLHII_00340 7.1e-98 E GDSL-like Lipase/Acylhydrolase
MKGHLHII_00341 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
MKGHLHII_00342 1.6e-143 aatB ET ABC transporter substrate-binding protein
MKGHLHII_00343 1e-105 glnQ 3.6.3.21 E ABC transporter
MKGHLHII_00344 1.5e-107 glnP P ABC transporter permease
MKGHLHII_00345 0.0 helD 3.6.4.12 L DNA helicase
MKGHLHII_00346 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MKGHLHII_00347 1.4e-126 pgm3 G Phosphoglycerate mutase family
MKGHLHII_00348 1.2e-241 S response to antibiotic
MKGHLHII_00349 4.9e-125
MKGHLHII_00350 0.0 3.6.3.8 P P-type ATPase
MKGHLHII_00351 8.7e-66 2.7.1.191 G PTS system fructose IIA component
MKGHLHII_00352 4.4e-43
MKGHLHII_00353 5.9e-09
MKGHLHII_00354 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
MKGHLHII_00355 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
MKGHLHII_00356 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
MKGHLHII_00357 5.2e-104
MKGHLHII_00360 1.9e-117 cps1D M Domain of unknown function (DUF4422)
MKGHLHII_00361 6.7e-110 rfbP M Bacterial sugar transferase
MKGHLHII_00362 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
MKGHLHII_00363 1.3e-121 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MKGHLHII_00364 6.5e-146 epsB M biosynthesis protein
MKGHLHII_00365 1.9e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MKGHLHII_00367 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKGHLHII_00368 3.5e-175 S Cysteine-rich secretory protein family
MKGHLHII_00369 1.6e-41
MKGHLHII_00370 2.6e-118 M NlpC/P60 family
MKGHLHII_00371 1.4e-136 M NlpC P60 family protein
MKGHLHII_00372 5e-88 M NlpC/P60 family
MKGHLHII_00373 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
MKGHLHII_00374 3.9e-42
MKGHLHII_00375 2.9e-279 S O-antigen ligase like membrane protein
MKGHLHII_00376 3.3e-112
MKGHLHII_00377 4.7e-221 tnpB L Putative transposase DNA-binding domain
MKGHLHII_00378 5.5e-77 nrdI F NrdI Flavodoxin like
MKGHLHII_00379 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKGHLHII_00380 2.5e-68
MKGHLHII_00381 9.1e-112 yvpB S Peptidase_C39 like family
MKGHLHII_00382 1.1e-83 S Threonine/Serine exporter, ThrE
MKGHLHII_00383 2.4e-136 thrE S Putative threonine/serine exporter
MKGHLHII_00384 8.9e-292 S ABC transporter
MKGHLHII_00385 8.3e-58
MKGHLHII_00386 5e-72 rimL J Acetyltransferase (GNAT) domain
MKGHLHII_00387 1.4e-34
MKGHLHII_00388 1.2e-30
MKGHLHII_00389 1.8e-111 S Protein of unknown function (DUF554)
MKGHLHII_00390 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MKGHLHII_00391 0.0 pepF E oligoendopeptidase F
MKGHLHII_00392 2.9e-31
MKGHLHII_00393 1.3e-69 doc S Prophage maintenance system killer protein
MKGHLHII_00396 4.6e-27 S Enterocin A Immunity
MKGHLHII_00397 1.7e-22 blpT
MKGHLHII_00399 1.6e-25 K Helix-turn-helix XRE-family like proteins
MKGHLHII_00400 1.2e-11
MKGHLHII_00401 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
MKGHLHII_00402 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MKGHLHII_00403 1e-263 lctP C L-lactate permease
MKGHLHII_00404 5e-129 znuB U ABC 3 transport family
MKGHLHII_00405 1.6e-117 fhuC P ABC transporter
MKGHLHII_00406 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
MKGHLHII_00407 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
MKGHLHII_00408 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
MKGHLHII_00409 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MKGHLHII_00410 1.8e-136 fruR K DeoR C terminal sensor domain
MKGHLHII_00411 1.8e-218 natB CP ABC-2 family transporter protein
MKGHLHII_00412 1.1e-164 natA S ABC transporter, ATP-binding protein
MKGHLHII_00413 1.7e-67
MKGHLHII_00414 2e-23
MKGHLHII_00415 8.2e-31 yozG K Transcriptional regulator
MKGHLHII_00416 9.5e-72
MKGHLHII_00417 3e-21
MKGHLHII_00421 2.2e-129 blpT
MKGHLHII_00422 1.4e-107 M Transport protein ComB
MKGHLHII_00423 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MKGHLHII_00424 1.2e-127 K LytTr DNA-binding domain
MKGHLHII_00425 1.6e-132 2.7.13.3 T GHKL domain
MKGHLHII_00426 1.2e-16
MKGHLHII_00427 2.1e-255 S Archaea bacterial proteins of unknown function
MKGHLHII_00428 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MKGHLHII_00429 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
MKGHLHII_00430 1e-24
MKGHLHII_00431 9.5e-26
MKGHLHII_00432 2.5e-33
MKGHLHII_00433 1.4e-53 S Enterocin A Immunity
MKGHLHII_00434 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MKGHLHII_00435 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKGHLHII_00436 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
MKGHLHII_00437 9.6e-121 K response regulator
MKGHLHII_00439 0.0 V ABC transporter
MKGHLHII_00440 4.2e-144 V ABC transporter, ATP-binding protein
MKGHLHII_00441 1.2e-145 V ABC transporter, ATP-binding protein
MKGHLHII_00442 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
MKGHLHII_00443 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MKGHLHII_00444 2.8e-44 yyzM S Bacterial protein of unknown function (DUF951)
MKGHLHII_00445 8.5e-154 spo0J K Belongs to the ParB family
MKGHLHII_00446 3.4e-138 soj D Sporulation initiation inhibitor
MKGHLHII_00447 1.5e-147 noc K Belongs to the ParB family
MKGHLHII_00448 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MKGHLHII_00449 3e-53 cvpA S Colicin V production protein
MKGHLHII_00451 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MKGHLHII_00452 6e-151 3.1.3.48 T Tyrosine phosphatase family
MKGHLHII_00453 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
MKGHLHII_00454 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
MKGHLHII_00455 2.4e-110 K WHG domain
MKGHLHII_00456 3e-37
MKGHLHII_00457 5.6e-36
MKGHLHII_00458 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKGHLHII_00459 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
MKGHLHII_00460 2.8e-135
MKGHLHII_00461 1.3e-258 glnPH2 P ABC transporter permease
MKGHLHII_00462 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MKGHLHII_00463 6.4e-224 S Cysteine-rich secretory protein family
MKGHLHII_00464 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MKGHLHII_00465 1.4e-112
MKGHLHII_00466 6.3e-202 yibE S overlaps another CDS with the same product name
MKGHLHII_00467 4.9e-129 yibF S overlaps another CDS with the same product name
MKGHLHII_00468 2.5e-144 I alpha/beta hydrolase fold
MKGHLHII_00469 0.0 G Belongs to the glycosyl hydrolase 31 family
MKGHLHII_00470 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKGHLHII_00471 3.8e-273 pipD E Dipeptidase
MKGHLHII_00472 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MKGHLHII_00473 3.3e-176 hrtB V ABC transporter permease
MKGHLHII_00474 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
MKGHLHII_00475 3.5e-111 G phosphoglycerate mutase
MKGHLHII_00476 4.1e-141 aroD S Alpha/beta hydrolase family
MKGHLHII_00477 2.2e-142 S Belongs to the UPF0246 family
MKGHLHII_00478 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
MKGHLHII_00479 3.9e-186 S Putative peptidoglycan binding domain
MKGHLHII_00480 4e-16
MKGHLHII_00481 2.1e-92 liaI S membrane
MKGHLHII_00482 6.6e-70 XK27_02470 K LytTr DNA-binding domain
MKGHLHII_00483 1.2e-18 S Sugar efflux transporter for intercellular exchange
MKGHLHII_00484 1.3e-250 dtpT U amino acid peptide transporter
MKGHLHII_00485 0.0 pepN 3.4.11.2 E aminopeptidase
MKGHLHII_00486 2.8e-47 lysM M LysM domain
MKGHLHII_00487 1.3e-174
MKGHLHII_00488 1.7e-152 mdtG EGP Major facilitator Superfamily
MKGHLHII_00489 6.9e-47 mdtG EGP Major facilitator Superfamily
MKGHLHII_00490 4.6e-88 ymdB S Macro domain protein
MKGHLHII_00492 4.8e-28
MKGHLHII_00495 4.3e-67 K Helix-turn-helix XRE-family like proteins
MKGHLHII_00496 3.3e-147 malG P ABC transporter permease
MKGHLHII_00497 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
MKGHLHII_00498 1.3e-213 malE G Bacterial extracellular solute-binding protein
MKGHLHII_00499 6.8e-209 msmX P Belongs to the ABC transporter superfamily
MKGHLHII_00500 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MKGHLHII_00501 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MKGHLHII_00502 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MKGHLHII_00503 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
MKGHLHII_00504 0.0 fhaB M Rib/alpha-like repeat
MKGHLHII_00505 3.1e-178 yvdE K helix_turn _helix lactose operon repressor
MKGHLHII_00506 4.1e-36 ptp2 3.1.3.48 T Tyrosine phosphatase family
MKGHLHII_00507 4.1e-101 ptp2 3.1.3.48 T Tyrosine phosphatase family
MKGHLHII_00508 5.1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKGHLHII_00509 1.5e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MKGHLHII_00510 1.7e-184 G Transmembrane secretion effector
MKGHLHII_00511 6.1e-136 V ABC transporter transmembrane region
MKGHLHII_00512 7.1e-223 L transposase, IS605 OrfB family
MKGHLHII_00513 1.1e-75 V ABC transporter transmembrane region
MKGHLHII_00514 6.5e-64 L RelB antitoxin
MKGHLHII_00515 2.1e-131 cobQ S glutamine amidotransferase
MKGHLHII_00516 1.8e-81 M NlpC/P60 family
MKGHLHII_00519 2.6e-155
MKGHLHII_00520 7.8e-38
MKGHLHII_00521 2e-32
MKGHLHII_00522 6.2e-163 EG EamA-like transporter family
MKGHLHII_00523 5e-165 EG EamA-like transporter family
MKGHLHII_00524 1.2e-139 yicL EG EamA-like transporter family
MKGHLHII_00525 4.3e-107
MKGHLHII_00526 1.1e-110
MKGHLHII_00527 5.8e-186 XK27_05540 S DUF218 domain
MKGHLHII_00528 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
MKGHLHII_00529 4.7e-85
MKGHLHII_00530 3.9e-57
MKGHLHII_00531 4.7e-25 S Protein conserved in bacteria
MKGHLHII_00532 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
MKGHLHII_00533 7.7e-29 hicA S HicA toxin of bacterial toxin-antitoxin,
MKGHLHII_00534 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MKGHLHII_00535 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKGHLHII_00536 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKGHLHII_00539 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MKGHLHII_00540 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
MKGHLHII_00541 1.8e-230 steT_1 E amino acid
MKGHLHII_00542 2.2e-139 puuD S peptidase C26
MKGHLHII_00544 2.4e-172 V HNH endonuclease
MKGHLHII_00545 6.4e-135 S PFAM Archaeal ATPase
MKGHLHII_00546 9.2e-248 yifK E Amino acid permease
MKGHLHII_00547 9.7e-234 cycA E Amino acid permease
MKGHLHII_00548 7.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MKGHLHII_00549 0.0 clpE O AAA domain (Cdc48 subfamily)
MKGHLHII_00550 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
MKGHLHII_00551 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKGHLHII_00552 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
MKGHLHII_00553 0.0 XK27_06780 V ABC transporter permease
MKGHLHII_00554 1.9e-36
MKGHLHII_00555 7.9e-291 ytgP S Polysaccharide biosynthesis protein
MKGHLHII_00556 2.7e-137 lysA2 M Glycosyl hydrolases family 25
MKGHLHII_00557 2.3e-133 S Protein of unknown function (DUF975)
MKGHLHII_00558 7.6e-177 pbpX2 V Beta-lactamase
MKGHLHII_00559 7.3e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MKGHLHII_00560 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKGHLHII_00561 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
MKGHLHII_00562 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKGHLHII_00563 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
MKGHLHII_00564 4.1e-44
MKGHLHII_00565 1e-207 ywhK S Membrane
MKGHLHII_00566 1.5e-80 ykuL S (CBS) domain
MKGHLHII_00567 0.0 cadA P P-type ATPase
MKGHLHII_00568 2.8e-205 napA P Sodium/hydrogen exchanger family
MKGHLHII_00569 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MKGHLHII_00570 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
MKGHLHII_00571 4.1e-276 V ABC transporter transmembrane region
MKGHLHII_00572 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
MKGHLHII_00573 5.4e-51
MKGHLHII_00574 4.2e-154 EGP Major facilitator Superfamily
MKGHLHII_00575 3e-111 ropB K Transcriptional regulator
MKGHLHII_00576 2.7e-120 S CAAX protease self-immunity
MKGHLHII_00577 1.6e-194 S DUF218 domain
MKGHLHII_00578 0.0 macB_3 V ABC transporter, ATP-binding protein
MKGHLHII_00579 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MKGHLHII_00580 2.8e-100 S ECF transporter, substrate-specific component
MKGHLHII_00581 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
MKGHLHII_00582 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
MKGHLHII_00583 1.4e-281 xylG 3.6.3.17 S ABC transporter
MKGHLHII_00584 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
MKGHLHII_00585 2.2e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
MKGHLHII_00586 3.7e-159 yeaE S Aldo/keto reductase family
MKGHLHII_00587 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKGHLHII_00588 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MKGHLHII_00589 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MKGHLHII_00590 9.4e-72
MKGHLHII_00591 8.2e-140 cof S haloacid dehalogenase-like hydrolase
MKGHLHII_00592 8.2e-230 pbuG S permease
MKGHLHII_00593 2.1e-76 S ABC-2 family transporter protein
MKGHLHII_00594 4.7e-60 S ABC-2 family transporter protein
MKGHLHII_00595 8.8e-83 V ABC transporter, ATP-binding protein
MKGHLHII_00596 2.5e-119 K helix_turn_helix, mercury resistance
MKGHLHII_00597 7.5e-231 pbuG S permease
MKGHLHII_00598 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
MKGHLHII_00599 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
MKGHLHII_00600 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
MKGHLHII_00602 1.9e-83 K Transcriptional regulator
MKGHLHII_00603 6.1e-61 K Transcriptional regulator
MKGHLHII_00604 2e-225 S cog cog1373
MKGHLHII_00605 2.8e-145 S haloacid dehalogenase-like hydrolase
MKGHLHII_00606 2.5e-226 pbuG S permease
MKGHLHII_00607 5.2e-08
MKGHLHII_00608 3e-89 ntd 2.4.2.6 F Nucleoside
MKGHLHII_00609 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKGHLHII_00610 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
MKGHLHII_00611 2.2e-82 uspA T universal stress protein
MKGHLHII_00613 1.2e-161 phnD P Phosphonate ABC transporter
MKGHLHII_00614 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MKGHLHII_00615 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MKGHLHII_00616 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MKGHLHII_00617 1.4e-81 L COG3385 FOG Transposase and inactivated derivatives
MKGHLHII_00618 1.4e-37 S Putative adhesin
MKGHLHII_00619 2.6e-151 V ABC transporter transmembrane region
MKGHLHII_00620 4.6e-138
MKGHLHII_00621 1.8e-31
MKGHLHII_00624 2.4e-36
MKGHLHII_00625 9.2e-57 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MKGHLHII_00626 1.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MKGHLHII_00627 0.0 copA 3.6.3.54 P P-type ATPase
MKGHLHII_00628 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MKGHLHII_00629 1.2e-105
MKGHLHII_00630 7e-248 EGP Sugar (and other) transporter
MKGHLHII_00631 1.2e-18
MKGHLHII_00632 2.8e-210
MKGHLHII_00633 3.5e-136 S SLAP domain
MKGHLHII_00634 1.3e-117 S SLAP domain
MKGHLHII_00635 1.1e-106 S Bacteriocin helveticin-J
MKGHLHII_00636 1.2e-44
MKGHLHII_00637 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
MKGHLHII_00638 4e-32 E Zn peptidase
MKGHLHII_00639 3.9e-287 clcA P chloride
MKGHLHII_00640 4.9e-08
MKGHLHII_00645 3.5e-65 2.1.1.72 KL DNA methylase
MKGHLHII_00646 1.2e-71 S N-methyltransferase activity
MKGHLHII_00651 3.6e-186 S Terminase-like family
MKGHLHII_00652 9.6e-91 S Protein of unknown function (DUF1073)
MKGHLHII_00653 6.9e-54 S Phage Mu protein F like protein
MKGHLHII_00654 3.7e-20 S Lysin motif
MKGHLHII_00655 5.6e-52 S Uncharacterized protein conserved in bacteria (DUF2213)
MKGHLHII_00656 5.8e-23
MKGHLHII_00657 7.7e-37 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
MKGHLHII_00658 1.6e-27 S Protein of unknown function (DUF4054)
MKGHLHII_00659 7.7e-42
MKGHLHII_00660 2.7e-10
MKGHLHII_00661 4.8e-27
MKGHLHII_00662 1.7e-133 Z012_02110 S Protein of unknown function (DUF3383)
MKGHLHII_00663 2.3e-11
MKGHLHII_00664 1.1e-11
MKGHLHII_00665 2.9e-193 M Phage tail tape measure protein TP901
MKGHLHII_00666 4.2e-58 M LysM domain
MKGHLHII_00667 2.7e-46
MKGHLHII_00668 5.1e-103
MKGHLHII_00669 5.9e-37
MKGHLHII_00670 7.4e-29
MKGHLHII_00671 7.4e-113 Z012_12235 S Baseplate J-like protein
MKGHLHII_00672 1.4e-09
MKGHLHII_00673 3.4e-35
MKGHLHII_00674 6.4e-70
MKGHLHII_00679 1.2e-10
MKGHLHII_00681 1.7e-16
MKGHLHII_00683 7e-16
MKGHLHII_00684 8e-27
MKGHLHII_00685 4.1e-177 M Glycosyl hydrolases family 25
MKGHLHII_00688 3.8e-48 M LysM domain protein
MKGHLHII_00689 2.9e-15 M LysM domain protein
MKGHLHII_00690 5.3e-139 L hmm pf00665
MKGHLHII_00691 1.4e-98 L Helix-turn-helix domain
MKGHLHII_00692 3.3e-86 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
MKGHLHII_00693 3.6e-240 V N-6 DNA Methylase
MKGHLHII_00694 2.4e-99 L An automated process has identified a potential problem with this gene model
MKGHLHII_00695 8.3e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MKGHLHII_00696 3.5e-57 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKGHLHII_00697 6.5e-18 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MKGHLHII_00698 9.7e-205 gatC G PTS system sugar-specific permease component
MKGHLHII_00699 1.2e-24 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2
MKGHLHII_00701 7.9e-16 L An automated process has identified a potential problem with this gene model
MKGHLHII_00702 9.4e-51 L An automated process has identified a potential problem with this gene model
MKGHLHII_00704 1e-66 doc S Fic/DOC family
MKGHLHII_00705 4.1e-34
MKGHLHII_00707 4.9e-24 S CAAX protease self-immunity
MKGHLHII_00709 1.3e-133 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MKGHLHII_00711 9.6e-18 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
MKGHLHII_00712 2.8e-23 relB L Addiction module antitoxin, RelB DinJ family
MKGHLHII_00713 6.1e-48 E Pfam:DUF955
MKGHLHII_00715 1.5e-36 oppA E ABC transporter substrate-binding protein
MKGHLHII_00717 1.4e-31 O OsmC-like protein
MKGHLHII_00718 9.1e-09 S CAAX protease self-immunity
MKGHLHII_00719 2.5e-75 K Helix-turn-helix domain
MKGHLHII_00720 4.9e-111 K Helix-turn-helix XRE-family like proteins
MKGHLHII_00723 8.8e-29
MKGHLHII_00725 8.2e-85 scrR K Periplasmic binding protein domain
MKGHLHII_00726 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MKGHLHII_00727 2.1e-111 S Fic/DOC family
MKGHLHII_00728 5.5e-38 L Protein of unknown function (DUF3991)
MKGHLHII_00729 1.1e-53 S COG0790 FOG TPR repeat, SEL1 subfamily
MKGHLHII_00735 3.4e-17 CO COG0526, thiol-disulfide isomerase and thioredoxins
MKGHLHII_00738 1.2e-32 M Peptidase family M23
MKGHLHII_00739 1.8e-159 trsE S COG0433 Predicted ATPase
MKGHLHII_00740 8.4e-15
MKGHLHII_00742 3.9e-32 I mechanosensitive ion channel activity
MKGHLHII_00743 1.2e-140 U TraM recognition site of TraD and TraG
MKGHLHII_00747 7.9e-31 M domain protein
MKGHLHII_00748 6.8e-15 S SLAP domain
MKGHLHII_00749 3.5e-42 M domain protein
MKGHLHII_00751 1.4e-24 srtA 3.4.22.70 M sortase family
MKGHLHII_00752 6.2e-22 S SLAP domain
MKGHLHII_00758 3.3e-11 S Single-strand binding protein family
MKGHLHII_00759 1.6e-10
MKGHLHII_00766 2.7e-34
MKGHLHII_00767 1.2e-128 S interspecies interaction between organisms
MKGHLHII_00769 9.1e-10 K peptidyl-tyrosine sulfation
MKGHLHII_00770 7.1e-263 E ABC transporter, substratebinding protein
MKGHLHII_00771 3.7e-66 K Helix-turn-helix domain, rpiR family
MKGHLHII_00772 2.6e-123 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MKGHLHII_00773 8.4e-90 nanK GK ROK family
MKGHLHII_00774 3.1e-56 G Xylose isomerase domain protein TIM barrel
MKGHLHII_00775 2.1e-120 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MKGHLHII_00776 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKGHLHII_00777 1.3e-67 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MKGHLHII_00778 5.7e-24 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MKGHLHII_00779 7.7e-110 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MKGHLHII_00780 2.8e-125 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKGHLHII_00781 1.4e-107 yisY 1.11.1.10 S Alpha/beta hydrolase family
MKGHLHII_00782 3.5e-108 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MKGHLHII_00783 6.1e-111 crt 4.2.1.17 I Enoyl-CoA hydratase/isomerase
MKGHLHII_00784 9.3e-151 fabK 1.3.1.9 S Nitronate monooxygenase
MKGHLHII_00785 1.6e-82 2.8.3.1 I Coenzyme A transferase
MKGHLHII_00786 5.8e-151 2.8.3.1 I Coenzyme A transferase
MKGHLHII_00787 3.7e-144 gltC_1 3.1.3.48 K LysR substrate binding domain
MKGHLHII_00788 1.5e-54 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MKGHLHII_00789 3.2e-75 S ECF transporter, substrate-specific component
MKGHLHII_00790 3.8e-80 coaA 2.7.1.33 F Pantothenic acid kinase
MKGHLHII_00791 2.7e-79 L Belongs to the 'phage' integrase family
MKGHLHII_00793 2.2e-15 E Pfam:DUF955
MKGHLHII_00795 4.7e-18 K Helix-turn-helix XRE-family like proteins
MKGHLHII_00796 4.4e-79 S Phage antirepressor protein KilAC domain
MKGHLHII_00797 3.5e-46
MKGHLHII_00803 1.6e-70 S AAA domain
MKGHLHII_00805 1.4e-147 res L Helicase C-terminal domain protein
MKGHLHII_00806 1.7e-30 S Protein of unknown function (DUF669)
MKGHLHII_00807 2.7e-268 S Phage plasmid primase, P4
MKGHLHII_00820 3.6e-34 S Phage derived protein Gp49-like (DUF891)
MKGHLHII_00821 7.1e-35 K Helix-turn-helix XRE-family like proteins
MKGHLHII_00823 1.1e-188 L N-6 DNA Methylase
MKGHLHII_00824 2.2e-26 S Type I restriction modification DNA specificity domain
MKGHLHII_00828 8.5e-151 L Belongs to the 'phage' integrase family
MKGHLHII_00829 5e-08 S Pfam:DUF955
MKGHLHII_00830 2.2e-25 K Helix-turn-helix domain
MKGHLHII_00831 1.3e-20 XK27_07105 K Helix-turn-helix XRE-family like proteins
MKGHLHII_00832 1.7e-174 L COG3385 FOG Transposase and inactivated derivatives
MKGHLHII_00833 1.6e-105 tag 3.2.2.20 L glycosylase
MKGHLHII_00834 3.9e-84
MKGHLHII_00835 1.7e-273 S Calcineurin-like phosphoesterase
MKGHLHII_00836 0.0 asnB 6.3.5.4 E Asparagine synthase
MKGHLHII_00837 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
MKGHLHII_00838 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MKGHLHII_00839 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MKGHLHII_00840 2.1e-103 S Iron-sulfur cluster assembly protein
MKGHLHII_00841 1.5e-230 XK27_04775 S PAS domain
MKGHLHII_00842 1e-210 yttB EGP Major facilitator Superfamily
MKGHLHII_00843 2.9e-247 mntH P H( )-stimulated, divalent metal cation uptake system
MKGHLHII_00844 5.3e-45 yitW S Iron-sulfur cluster assembly protein
MKGHLHII_00845 2e-266 sufB O assembly protein SufB
MKGHLHII_00846 2.4e-59 nifU C SUF system FeS assembly protein, NifU family
MKGHLHII_00847 5.3e-178 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKGHLHII_00848 3.5e-174 sufD O FeS assembly protein SufD
MKGHLHII_00849 2.8e-140 sufC O FeS assembly ATPase SufC
MKGHLHII_00850 8.5e-128 S Fic/DOC family
MKGHLHII_00851 1.9e-166 repA S Replication initiator protein A
MKGHLHII_00852 1.7e-142 soj D AAA domain
MKGHLHII_00853 1.3e-28
MKGHLHII_00854 1.1e-76 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MKGHLHII_00855 4.7e-70 L IS1381, transposase OrfA
MKGHLHII_00856 4.7e-47 tnpR1 L Resolvase, N terminal domain
MKGHLHII_00857 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
MKGHLHII_00858 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
MKGHLHII_00859 2.5e-264 3.6.3.6 P Cation transporter/ATPase, N-terminus
MKGHLHII_00860 1.9e-19
MKGHLHII_00861 4e-60 L Resolvase, N terminal domain
MKGHLHII_00862 8.7e-26 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MKGHLHII_00863 2.3e-101 L An automated process has identified a potential problem with this gene model
MKGHLHII_00864 2.1e-45 S O-antigen ligase like membrane protein
MKGHLHII_00865 5.1e-82 glfT1 1.1.1.133 S Glycosyltransferase, group 2 family protein
MKGHLHII_00866 5.3e-76 M Glycosyltransferase, group 1 family protein
MKGHLHII_00867 1.7e-42 M Glycosyl transferase family 2
MKGHLHII_00868 4e-40 S CRISPR-associated protein (Cas_Csn2)
MKGHLHII_00869 8.3e-40 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MKGHLHII_00870 3e-130 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MKGHLHII_00871 3.7e-92 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MKGHLHII_00872 1.8e-81 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MKGHLHII_00873 1e-78 S helix_turn_helix, Deoxyribose operon repressor
MKGHLHII_00874 3.3e-140 repB EP Plasmid replication protein
MKGHLHII_00875 2.2e-22
MKGHLHII_00877 7.6e-07 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
MKGHLHII_00880 1.5e-26 S Domain of unknown function (DUF771)
MKGHLHII_00882 0.0 pepO 3.4.24.71 O Peptidase family M13
MKGHLHII_00883 1.1e-101 L Integrase
MKGHLHII_00884 3.6e-69 T Toxin-antitoxin system, toxin component, MazF family
MKGHLHII_00885 1.3e-30
MKGHLHII_00886 2.2e-54 oppA E ABC transporter substrate-binding protein
MKGHLHII_00887 1.3e-149 oppA E ABC transporter substrate-binding protein
MKGHLHII_00888 3e-270 L Transposase DDE domain
MKGHLHII_00889 1.5e-234 L Transposase DDE domain
MKGHLHII_00890 7e-240 L Transposase DDE domain
MKGHLHII_00891 3e-112 L PFAM transposase IS116 IS110 IS902
MKGHLHII_00892 9.6e-184 L DDE superfamily endonuclease
MKGHLHII_00893 1.9e-89 ydiM G Major facilitator superfamily
MKGHLHII_00894 2.3e-184 S Uncharacterised protein family (UPF0236)
MKGHLHII_00895 1.2e-47 L Transposase, IS116 IS110 IS902 family
MKGHLHII_00897 0.0 kup P Transport of potassium into the cell
MKGHLHII_00898 7.3e-74
MKGHLHII_00899 2.1e-45 S PFAM Archaeal ATPase
MKGHLHII_00901 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MKGHLHII_00902 5.9e-45
MKGHLHII_00903 2.2e-170 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MKGHLHII_00904 1.6e-77 ybhL S Belongs to the BI1 family
MKGHLHII_00905 1.8e-79
MKGHLHII_00907 5.3e-41
MKGHLHII_00908 1.4e-76 K DNA-templated transcription, initiation
MKGHLHII_00909 1.1e-25
MKGHLHII_00910 2.1e-144 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MKGHLHII_00912 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MKGHLHII_00913 2.2e-100 S SLAP domain
MKGHLHII_00914 4.3e-40 S Protein of unknown function (DUF2922)
MKGHLHII_00915 5.5e-30
MKGHLHII_00917 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MKGHLHII_00918 5.7e-69 rplI J Binds to the 23S rRNA
MKGHLHII_00919 1.9e-253 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MKGHLHII_00920 1.4e-131 S SLAP domain
MKGHLHII_00922 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MKGHLHII_00923 6.5e-180 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
MKGHLHII_00924 0.0 yjbQ P TrkA C-terminal domain protein
MKGHLHII_00925 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MKGHLHII_00926 2.1e-161 S Oxidoreductase family, NAD-binding Rossmann fold
MKGHLHII_00927 2.1e-130
MKGHLHII_00928 2.1e-116
MKGHLHII_00929 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MKGHLHII_00930 1.4e-98 G Aldose 1-epimerase
MKGHLHII_00931 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MKGHLHII_00932 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MKGHLHII_00933 0.0 XK27_08315 M Sulfatase
MKGHLHII_00934 8.4e-265 S Fibronectin type III domain
MKGHLHII_00935 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKGHLHII_00936 3.4e-53
MKGHLHII_00938 4.6e-257 pepC 3.4.22.40 E aminopeptidase
MKGHLHII_00939 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MKGHLHII_00940 1.7e-301 oppA E ABC transporter, substratebinding protein
MKGHLHII_00941 1.6e-310 oppA E ABC transporter, substratebinding protein
MKGHLHII_00942 3.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKGHLHII_00943 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKGHLHII_00944 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKGHLHII_00945 2.7e-199 oppD P Belongs to the ABC transporter superfamily
MKGHLHII_00946 1.9e-175 oppF P Belongs to the ABC transporter superfamily
MKGHLHII_00947 1.4e-256 pepC 3.4.22.40 E aminopeptidase
MKGHLHII_00948 3.9e-72 hsp O Belongs to the small heat shock protein (HSP20) family
MKGHLHII_00949 1.3e-28 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKGHLHII_00950 6e-112
MKGHLHII_00952 1.7e-110 E Belongs to the SOS response-associated peptidase family
MKGHLHII_00953 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MKGHLHII_00954 4e-89 comEB 3.5.4.12 F MafB19-like deaminase
MKGHLHII_00955 2.2e-102 S TPM domain
MKGHLHII_00956 2.4e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MKGHLHII_00957 2.5e-311 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MKGHLHII_00958 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKGHLHII_00959 1e-147 tatD L hydrolase, TatD family
MKGHLHII_00960 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKGHLHII_00961 6.7e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MKGHLHII_00962 4.5e-39 veg S Biofilm formation stimulator VEG
MKGHLHII_00963 1.5e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MKGHLHII_00964 4.9e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MKGHLHII_00965 5.3e-80
MKGHLHII_00966 7.8e-292 S SLAP domain
MKGHLHII_00967 7.9e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKGHLHII_00968 6e-38 L Transposase and inactivated derivatives, IS30 family
MKGHLHII_00969 4.2e-172 2.7.1.2 GK ROK family
MKGHLHII_00970 5.6e-43
MKGHLHII_00971 3.6e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
MKGHLHII_00972 6.9e-69 S Domain of unknown function (DUF1934)
MKGHLHII_00973 1.5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MKGHLHII_00974 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MKGHLHII_00975 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKGHLHII_00976 1.8e-74 K acetyltransferase
MKGHLHII_00977 5.7e-285 pipD E Dipeptidase
MKGHLHII_00978 8.3e-156 msmR K AraC-like ligand binding domain
MKGHLHII_00979 1.5e-223 pbuX F xanthine permease
MKGHLHII_00980 9e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MKGHLHII_00981 2.4e-43 K Helix-turn-helix
MKGHLHII_00982 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MKGHLHII_00984 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MKGHLHII_00985 3.6e-225 3.2.1.18 GH33 M Rib/alpha-like repeat
MKGHLHII_00986 1.2e-141 yfeO P Voltage gated chloride channel
MKGHLHII_00987 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
MKGHLHII_00988 1.4e-51
MKGHLHII_00989 2.1e-42
MKGHLHII_00990 5.4e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKGHLHII_00991 9.5e-297 ybeC E amino acid
MKGHLHII_00992 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
MKGHLHII_00993 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
MKGHLHII_00994 2.5e-39 rpmE2 J Ribosomal protein L31
MKGHLHII_00995 1.2e-258 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MKGHLHII_00996 4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MKGHLHII_00997 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MKGHLHII_00998 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKGHLHII_00999 3.4e-129 S (CBS) domain
MKGHLHII_01000 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MKGHLHII_01001 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MKGHLHII_01002 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MKGHLHII_01003 1.6e-33 yabO J S4 domain protein
MKGHLHII_01004 6.8e-60 divIC D Septum formation initiator
MKGHLHII_01005 1.8e-62 yabR J S1 RNA binding domain
MKGHLHII_01006 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MKGHLHII_01007 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKGHLHII_01008 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MKGHLHII_01009 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKGHLHII_01010 1.1e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MKGHLHII_01011 1.4e-83 K FR47-like protein
MKGHLHII_01012 1.6e-08
MKGHLHII_01014 1.7e-69 yebR 1.8.4.14 T GAF domain-containing protein
MKGHLHII_01015 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MKGHLHII_01016 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKGHLHII_01017 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKGHLHII_01018 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MKGHLHII_01019 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MKGHLHII_01020 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MKGHLHII_01021 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKGHLHII_01022 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MKGHLHII_01023 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MKGHLHII_01024 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
MKGHLHII_01025 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MKGHLHII_01026 3.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MKGHLHII_01027 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MKGHLHII_01028 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MKGHLHII_01029 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MKGHLHII_01030 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MKGHLHII_01031 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MKGHLHII_01032 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MKGHLHII_01033 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MKGHLHII_01034 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MKGHLHII_01035 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MKGHLHII_01036 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKGHLHII_01037 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MKGHLHII_01038 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MKGHLHII_01039 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MKGHLHII_01040 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MKGHLHII_01041 2.3e-24 rpmD J Ribosomal protein L30
MKGHLHII_01042 1.3e-70 rplO J Binds to the 23S rRNA
MKGHLHII_01043 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MKGHLHII_01044 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MKGHLHII_01045 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MKGHLHII_01046 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MKGHLHII_01047 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MKGHLHII_01048 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MKGHLHII_01049 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKGHLHII_01050 1.4e-60 rplQ J Ribosomal protein L17
MKGHLHII_01051 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKGHLHII_01052 3.5e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKGHLHII_01053 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKGHLHII_01054 4.8e-148 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MKGHLHII_01055 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MKGHLHII_01056 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
MKGHLHII_01057 3.6e-183 L Phage integrase family
MKGHLHII_01058 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MKGHLHII_01059 3.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MKGHLHII_01060 6e-132 S membrane transporter protein
MKGHLHII_01061 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
MKGHLHII_01062 7.3e-161 czcD P cation diffusion facilitator family transporter
MKGHLHII_01063 1.4e-23
MKGHLHII_01064 2.6e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MKGHLHII_01065 5.4e-183 S AAA domain
MKGHLHII_01066 7.3e-44
MKGHLHII_01067 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
MKGHLHII_01068 4.1e-52
MKGHLHII_01069 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MKGHLHII_01070 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKGHLHII_01071 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKGHLHII_01072 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MKGHLHII_01073 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MKGHLHII_01074 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKGHLHII_01075 1.2e-94 sigH K Belongs to the sigma-70 factor family
MKGHLHII_01076 1.7e-34
MKGHLHII_01077 1.9e-286 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MKGHLHII_01078 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MKGHLHII_01079 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MKGHLHII_01080 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
MKGHLHII_01081 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MKGHLHII_01082 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MKGHLHII_01083 2.8e-157 pstS P Phosphate
MKGHLHII_01084 1.9e-162 pstC P probably responsible for the translocation of the substrate across the membrane
MKGHLHII_01085 6.5e-154 pstA P Phosphate transport system permease protein PstA
MKGHLHII_01086 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKGHLHII_01087 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKGHLHII_01088 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
MKGHLHII_01089 4.8e-90 L An automated process has identified a potential problem with this gene model
MKGHLHII_01090 1.5e-11 GT2,GT4 M family 8
MKGHLHII_01091 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MKGHLHII_01092 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MKGHLHII_01093 8.7e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
MKGHLHII_01094 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
MKGHLHII_01095 9e-26
MKGHLHII_01096 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MKGHLHII_01097 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKGHLHII_01098 5.7e-106 2.4.1.58 GT8 M family 8
MKGHLHII_01099 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
MKGHLHII_01100 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MKGHLHII_01101 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MKGHLHII_01102 1.1e-34 S Protein of unknown function (DUF2508)
MKGHLHII_01103 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MKGHLHII_01104 8.9e-53 yaaQ S Cyclic-di-AMP receptor
MKGHLHII_01105 1.5e-155 holB 2.7.7.7 L DNA polymerase III
MKGHLHII_01106 1.8e-59 yabA L Involved in initiation control of chromosome replication
MKGHLHII_01107 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKGHLHII_01108 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
MKGHLHII_01109 2.2e-85 S ECF transporter, substrate-specific component
MKGHLHII_01110 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MKGHLHII_01111 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MKGHLHII_01112 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MKGHLHII_01113 1.9e-245 L Transposase IS66 family
MKGHLHII_01114 8.7e-34 S Transposase C of IS166 homeodomain
MKGHLHII_01115 9.3e-64 L PFAM IS66 Orf2 family protein
MKGHLHII_01116 7.7e-22
MKGHLHII_01117 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MKGHLHII_01118 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MKGHLHII_01119 1.3e-283 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
MKGHLHII_01120 0.0 uup S ABC transporter, ATP-binding protein
MKGHLHII_01121 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MKGHLHII_01122 3.3e-164 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
MKGHLHII_01123 5.2e-170 degV S DegV family
MKGHLHII_01124 1.1e-183 scrR K helix_turn _helix lactose operon repressor
MKGHLHII_01125 3.7e-295 scrB 3.2.1.26 GH32 G invertase
MKGHLHII_01126 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
MKGHLHII_01127 2.3e-181 M CHAP domain
MKGHLHII_01128 3.5e-75
MKGHLHII_01129 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MKGHLHII_01130 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MKGHLHII_01131 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MKGHLHII_01132 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MKGHLHII_01133 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MKGHLHII_01134 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MKGHLHII_01135 9.6e-41 yajC U Preprotein translocase
MKGHLHII_01136 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKGHLHII_01137 6.2e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKGHLHII_01138 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MKGHLHII_01139 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MKGHLHII_01140 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MKGHLHII_01141 2e-42 yrzL S Belongs to the UPF0297 family
MKGHLHII_01142 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MKGHLHII_01143 1.1e-50 yrzB S Belongs to the UPF0473 family
MKGHLHII_01144 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MKGHLHII_01145 3.5e-54 trxA O Belongs to the thioredoxin family
MKGHLHII_01146 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MKGHLHII_01147 1.1e-71 yslB S Protein of unknown function (DUF2507)
MKGHLHII_01148 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MKGHLHII_01149 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MKGHLHII_01150 7.7e-30 ropB K Helix-turn-helix domain
MKGHLHII_01151 5.4e-113
MKGHLHII_01152 1.7e-139
MKGHLHII_01153 1.2e-99 V ATPases associated with a variety of cellular activities
MKGHLHII_01154 3.7e-146 ykuT M mechanosensitive ion channel
MKGHLHII_01155 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKGHLHII_01156 1.3e-36
MKGHLHII_01157 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MKGHLHII_01158 3.2e-181 ccpA K catabolite control protein A
MKGHLHII_01159 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MKGHLHII_01160 4.3e-55
MKGHLHII_01161 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MKGHLHII_01162 2.1e-92 yutD S Protein of unknown function (DUF1027)
MKGHLHII_01163 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MKGHLHII_01164 3.7e-100 S Protein of unknown function (DUF1461)
MKGHLHII_01165 6.8e-116 dedA S SNARE-like domain protein
MKGHLHII_01166 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
MKGHLHII_01194 5.1e-223 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
MKGHLHII_01195 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
MKGHLHII_01196 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKGHLHII_01197 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MKGHLHII_01198 1.7e-29 secG U Preprotein translocase
MKGHLHII_01199 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MKGHLHII_01200 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MKGHLHII_01202 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MKGHLHII_01203 1.7e-129 manY G PTS system
MKGHLHII_01204 1e-173 manN G system, mannose fructose sorbose family IID component
MKGHLHII_01205 1.1e-62 manO S Domain of unknown function (DUF956)
MKGHLHII_01206 3.3e-158 K Transcriptional regulator
MKGHLHII_01207 1.3e-85 maa S transferase hexapeptide repeat
MKGHLHII_01208 5.8e-242 cycA E Amino acid permease
MKGHLHII_01209 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MKGHLHII_01210 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MKGHLHII_01211 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MKGHLHII_01212 0.0 mtlR K Mga helix-turn-helix domain
MKGHLHII_01213 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
MKGHLHII_01214 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKGHLHII_01215 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
MKGHLHII_01216 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
MKGHLHII_01217 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
MKGHLHII_01218 2.1e-32
MKGHLHII_01219 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MKGHLHII_01220 2.3e-156 K Helix-turn-helix XRE-family like proteins
MKGHLHII_01221 3.9e-298 V ABC transporter transmembrane region
MKGHLHII_01222 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MKGHLHII_01223 1.7e-193 S TerB-C domain
MKGHLHII_01224 2.6e-138 S TerB-C domain
MKGHLHII_01225 1.4e-245 P P-loop Domain of unknown function (DUF2791)
MKGHLHII_01226 0.0 lhr L DEAD DEAH box helicase
MKGHLHII_01227 1.4e-60
MKGHLHII_01228 4.3e-228 amtB P ammonium transporter
MKGHLHII_01229 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MKGHLHII_01231 6.6e-61 psiE S Phosphate-starvation-inducible E
MKGHLHII_01232 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
MKGHLHII_01233 2.9e-69 S Iron-sulphur cluster biosynthesis
MKGHLHII_01235 2.3e-30
MKGHLHII_01236 2.6e-171 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
MKGHLHII_01237 6.2e-12
MKGHLHII_01238 5.4e-60 L Resolvase, N-terminal
MKGHLHII_01239 1.6e-166 L Putative transposase DNA-binding domain
MKGHLHII_01240 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKGHLHII_01241 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKGHLHII_01242 1.1e-85 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKGHLHII_01243 5.8e-78 M LysM domain protein
MKGHLHII_01244 4.7e-159 D nuclear chromosome segregation
MKGHLHII_01245 1.2e-105 G Phosphoglycerate mutase family
MKGHLHII_01246 2.6e-89 G Histidine phosphatase superfamily (branch 1)
MKGHLHII_01247 1.5e-118 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
MKGHLHII_01248 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MKGHLHII_01250 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MKGHLHII_01252 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MKGHLHII_01253 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
MKGHLHII_01254 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MKGHLHII_01255 4.4e-144 K SIS domain
MKGHLHII_01256 4.8e-44 slpX S SLAP domain
MKGHLHII_01257 5.3e-167 slpX S SLAP domain
MKGHLHII_01258 1.3e-22 3.6.4.12 S transposase or invertase
MKGHLHII_01259 6.6e-11
MKGHLHII_01260 3.2e-240 npr 1.11.1.1 C NADH oxidase
MKGHLHII_01263 4.4e-239 oppA2 E ABC transporter, substratebinding protein
MKGHLHII_01264 3.4e-45 oppA2 E ABC transporter, substratebinding protein
MKGHLHII_01265 2.8e-178
MKGHLHII_01266 4.6e-123 gntR1 K UTRA
MKGHLHII_01267 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
MKGHLHII_01268 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MKGHLHII_01269 1.7e-204 csaB M Glycosyl transferases group 1
MKGHLHII_01270 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKGHLHII_01271 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MKGHLHII_01272 1.4e-204 tnpB L Putative transposase DNA-binding domain
MKGHLHII_01273 0.0 pacL 3.6.3.8 P P-type ATPase
MKGHLHII_01274 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MKGHLHII_01275 6e-258 epsU S Polysaccharide biosynthesis protein
MKGHLHII_01276 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
MKGHLHII_01277 4.1e-83 ydcK S Belongs to the SprT family
MKGHLHII_01279 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
MKGHLHII_01280 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MKGHLHII_01281 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKGHLHII_01282 5.8e-203 camS S sex pheromone
MKGHLHII_01283 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKGHLHII_01284 3.2e-267 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MKGHLHII_01285 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKGHLHII_01286 2.7e-171 yegS 2.7.1.107 G Lipid kinase
MKGHLHII_01287 4.3e-108 ybhL S Belongs to the BI1 family
MKGHLHII_01288 2.6e-57
MKGHLHII_01289 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
MKGHLHII_01290 2.8e-244 nhaC C Na H antiporter NhaC
MKGHLHII_01291 6.3e-201 pbpX V Beta-lactamase
MKGHLHII_01292 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKGHLHII_01293 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
MKGHLHII_01298 1.9e-259 emrY EGP Major facilitator Superfamily
MKGHLHII_01299 2e-91 yxdD K Bacterial regulatory proteins, tetR family
MKGHLHII_01300 0.0 4.2.1.53 S Myosin-crossreactive antigen
MKGHLHII_01301 5.5e-148 S cog cog1373
MKGHLHII_01302 1.7e-226 L Transposase
MKGHLHII_01303 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
MKGHLHII_01304 2e-157 S reductase
MKGHLHII_01305 9.3e-35
MKGHLHII_01306 1.9e-22 K Putative DNA-binding domain
MKGHLHII_01307 7.6e-239 pyrP F Permease
MKGHLHII_01308 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MKGHLHII_01309 9.2e-262 emrY EGP Major facilitator Superfamily
MKGHLHII_01310 5.1e-155 mdtG EGP Major facilitator Superfamily
MKGHLHII_01311 1.1e-132 V ABC transporter transmembrane region
MKGHLHII_01312 1.8e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MKGHLHII_01314 1.4e-16
MKGHLHII_01315 4.7e-182 pepA E M42 glutamyl aminopeptidase
MKGHLHII_01316 2.2e-311 ybiT S ABC transporter, ATP-binding protein
MKGHLHII_01317 5.9e-174 S Aldo keto reductase
MKGHLHII_01318 2.7e-138
MKGHLHII_01319 2.8e-202 steT E amino acid
MKGHLHII_01320 2.4e-26 steT E amino acid
MKGHLHII_01321 4.3e-242 steT E amino acid
MKGHLHII_01322 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
MKGHLHII_01323 1.9e-147 glnH ET ABC transporter
MKGHLHII_01324 1.4e-80 K Transcriptional regulator, MarR family
MKGHLHII_01325 6.9e-309 XK27_09600 V ABC transporter, ATP-binding protein
MKGHLHII_01326 0.0 V ABC transporter transmembrane region
MKGHLHII_01327 1.6e-100 S ABC-type cobalt transport system, permease component
MKGHLHII_01328 1e-246 G MFS/sugar transport protein
MKGHLHII_01329 9.8e-39 udk 2.7.1.48 F Zeta toxin
MKGHLHII_01330 3.8e-46 udk 2.7.1.48 F Zeta toxin
MKGHLHII_01331 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MKGHLHII_01332 1.2e-146 glnH ET ABC transporter substrate-binding protein
MKGHLHII_01333 3.7e-90 gluC P ABC transporter permease
MKGHLHII_01334 4.7e-109 glnP P ABC transporter permease
MKGHLHII_01335 1.1e-164 S Protein of unknown function (DUF2974)
MKGHLHII_01336 5.6e-86
MKGHLHII_01337 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
MKGHLHII_01338 1.3e-235 G Bacterial extracellular solute-binding protein
MKGHLHII_01339 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
MKGHLHII_01340 3.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKGHLHII_01341 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MKGHLHII_01342 0.0 kup P Transport of potassium into the cell
MKGHLHII_01343 9.1e-175 rihB 3.2.2.1 F Nucleoside
MKGHLHII_01344 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
MKGHLHII_01345 1.2e-154 S hydrolase
MKGHLHII_01346 2.5e-59 S Enterocin A Immunity
MKGHLHII_01347 3.1e-136 glcR K DeoR C terminal sensor domain
MKGHLHII_01348 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MKGHLHII_01349 2e-160 rssA S Phospholipase, patatin family
MKGHLHII_01350 5.4e-147 S hydrolase
MKGHLHII_01351 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
MKGHLHII_01352 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
MKGHLHII_01353 1.6e-80
MKGHLHII_01354 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MKGHLHII_01355 2.1e-39
MKGHLHII_01356 3.9e-119 C nitroreductase
MKGHLHII_01357 1.7e-249 yhdP S Transporter associated domain
MKGHLHII_01358 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MKGHLHII_01359 0.0 1.3.5.4 C FAD binding domain
MKGHLHII_01360 1.4e-87 L PFAM transposase, IS4 family protein
MKGHLHII_01361 1.2e-49 L PFAM transposase, IS4 family protein
MKGHLHII_01362 1.7e-213 1.3.5.4 C FAD binding domain
MKGHLHII_01363 3.4e-126 1.3.5.4 C FAD binding domain
MKGHLHII_01364 9.7e-231 potE E amino acid
MKGHLHII_01365 2.6e-61 M Glycosyl hydrolases family 25
MKGHLHII_01366 8.3e-61 M Glycosyl hydrolases family 25
MKGHLHII_01367 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
MKGHLHII_01368 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKGHLHII_01370 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MKGHLHII_01371 7e-87 gtcA S Teichoic acid glycosylation protein
MKGHLHII_01372 4.1e-80 fld C Flavodoxin
MKGHLHII_01373 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
MKGHLHII_01374 3.6e-163 yihY S Belongs to the UPF0761 family
MKGHLHII_01375 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MKGHLHII_01376 5.6e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
MKGHLHII_01377 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MKGHLHII_01378 8.1e-175 ulaG S Beta-lactamase superfamily domain
MKGHLHII_01379 2.2e-60 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKGHLHII_01380 1.3e-231 ulaA S PTS system sugar-specific permease component
MKGHLHII_01381 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
MKGHLHII_01382 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
MKGHLHII_01383 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
MKGHLHII_01384 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MKGHLHII_01385 5.2e-68 L haloacid dehalogenase-like hydrolase
MKGHLHII_01386 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MKGHLHII_01387 1.4e-16 L Transposase
MKGHLHII_01388 1.9e-12 L Transposase
MKGHLHII_01389 5.9e-13 K Acetyltransferase (GNAT) domain
MKGHLHII_01390 9.4e-46
MKGHLHII_01391 1.8e-38 D Alpha beta
MKGHLHII_01392 1.4e-118 D Alpha beta
MKGHLHII_01393 3e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKGHLHII_01394 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
MKGHLHII_01395 1.6e-85
MKGHLHII_01396 2.7e-74
MKGHLHII_01397 1.4e-140 hlyX S Transporter associated domain
MKGHLHII_01398 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MKGHLHII_01399 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
MKGHLHII_01400 0.0 clpE O Belongs to the ClpA ClpB family
MKGHLHII_01401 3.3e-127 L PFAM transposase IS116 IS110 IS902
MKGHLHII_01402 5.3e-26
MKGHLHII_01403 8.5e-41 ptsH G phosphocarrier protein HPR
MKGHLHII_01404 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKGHLHII_01405 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MKGHLHII_01406 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MKGHLHII_01407 2.6e-91 coiA 3.6.4.12 S Competence protein
MKGHLHII_01408 6.4e-44 coiA 3.6.4.12 S Competence protein
MKGHLHII_01409 4.6e-114 yjbH Q Thioredoxin
MKGHLHII_01410 6.8e-110 yjbK S CYTH
MKGHLHII_01411 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
MKGHLHII_01412 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKGHLHII_01413 7.1e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MKGHLHII_01414 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
MKGHLHII_01415 4.2e-92 S SNARE associated Golgi protein
MKGHLHII_01416 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MKGHLHII_01417 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MKGHLHII_01418 2.6e-214 yubA S AI-2E family transporter
MKGHLHII_01419 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MKGHLHII_01420 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
MKGHLHII_01421 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MKGHLHII_01422 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
MKGHLHII_01423 1.9e-236 S Peptidase M16
MKGHLHII_01424 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
MKGHLHII_01425 1.5e-96 ymfM S Helix-turn-helix domain
MKGHLHII_01426 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKGHLHII_01427 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKGHLHII_01428 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
MKGHLHII_01429 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
MKGHLHII_01430 5.1e-119 yvyE 3.4.13.9 S YigZ family
MKGHLHII_01431 4.7e-246 comFA L Helicase C-terminal domain protein
MKGHLHII_01432 9.4e-132 comFC S Competence protein
MKGHLHII_01433 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKGHLHII_01434 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MKGHLHII_01435 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MKGHLHII_01436 5.1e-17
MKGHLHII_01437 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MKGHLHII_01438 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MKGHLHII_01439 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MKGHLHII_01440 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MKGHLHII_01441 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MKGHLHII_01442 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MKGHLHII_01443 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MKGHLHII_01444 4.1e-90 S Short repeat of unknown function (DUF308)
MKGHLHII_01445 6.2e-165 rapZ S Displays ATPase and GTPase activities
MKGHLHII_01446 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MKGHLHII_01447 2.1e-171 whiA K May be required for sporulation
MKGHLHII_01448 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MKGHLHII_01449 0.0 S SH3-like domain
MKGHLHII_01450 4.9e-111 ybbL S ABC transporter, ATP-binding protein
MKGHLHII_01451 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
MKGHLHII_01452 3.1e-48 S Domain of unknown function (DUF4811)
MKGHLHII_01453 1.4e-262 lmrB EGP Major facilitator Superfamily
MKGHLHII_01454 4.2e-77 K MerR HTH family regulatory protein
MKGHLHII_01455 3.1e-139 S Cysteine-rich secretory protein family
MKGHLHII_01456 4.6e-274 ycaM E amino acid
MKGHLHII_01457 2.8e-290
MKGHLHII_01459 3.3e-189 cggR K Putative sugar-binding domain
MKGHLHII_01460 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKGHLHII_01461 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MKGHLHII_01462 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MKGHLHII_01463 3e-198 L COG2826 Transposase and inactivated derivatives, IS30 family
MKGHLHII_01464 1.2e-94
MKGHLHII_01465 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
MKGHLHII_01466 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MKGHLHII_01467 1.2e-180 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MKGHLHII_01468 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MKGHLHII_01469 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
MKGHLHII_01470 2e-163 murB 1.3.1.98 M Cell wall formation
MKGHLHII_01471 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MKGHLHII_01472 1.3e-129 potB P ABC transporter permease
MKGHLHII_01473 4.8e-127 potC P ABC transporter permease
MKGHLHII_01474 7.3e-208 potD P ABC transporter
MKGHLHII_01475 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKGHLHII_01476 2e-172 ybbR S YbbR-like protein
MKGHLHII_01477 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKGHLHII_01478 1.4e-147 S hydrolase
MKGHLHII_01479 1.8e-75 K Penicillinase repressor
MKGHLHII_01480 1.6e-118
MKGHLHII_01481 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKGHLHII_01482 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MKGHLHII_01483 8.3e-143 licT K CAT RNA binding domain
MKGHLHII_01484 9.7e-297 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKGHLHII_01485 9.5e-62 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKGHLHII_01486 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKGHLHII_01487 1e-149 D Alpha beta
MKGHLHII_01488 1.9e-47 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
MKGHLHII_01489 5.6e-161 I Protein of unknown function (DUF2974)
MKGHLHII_01490 1.9e-116 yhiD S MgtC family
MKGHLHII_01492 7.6e-25 S SLAP domain
MKGHLHII_01493 4.3e-24 S SLAP domain
MKGHLHII_01494 3.3e-222 L Transposase
MKGHLHII_01495 8.5e-279 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MKGHLHII_01496 2.4e-34 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
MKGHLHII_01497 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
MKGHLHII_01498 5.2e-112 ica2 GT2 M Glycosyl transferase family group 2
MKGHLHII_01499 8.2e-36
MKGHLHII_01500 2.2e-90 2.7.7.65 T GGDEF domain
MKGHLHII_01501 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKGHLHII_01503 2e-310 E Amino acid permease
MKGHLHII_01504 5.8e-100 L Helix-turn-helix domain
MKGHLHII_01505 1.3e-160 L hmm pf00665
MKGHLHII_01507 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKGHLHII_01508 3.5e-101 ylbE GM NAD(P)H-binding
MKGHLHII_01509 7.6e-94 S VanZ like family
MKGHLHII_01510 8.9e-133 yebC K Transcriptional regulatory protein
MKGHLHII_01511 1.7e-179 comGA NU Type II IV secretion system protein
MKGHLHII_01512 1.7e-171 comGB NU type II secretion system
MKGHLHII_01513 3.1e-43 comGC U competence protein ComGC
MKGHLHII_01514 1.8e-69
MKGHLHII_01515 2.3e-41
MKGHLHII_01516 3.8e-77 comGF U Putative Competence protein ComGF
MKGHLHII_01517 1.6e-21
MKGHLHII_01518 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
MKGHLHII_01519 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKGHLHII_01521 3e-148 L Belongs to the 'phage' integrase family
MKGHLHII_01522 2.6e-09 S Pfam:DUF955
MKGHLHII_01523 1.1e-17 K Helix-turn-helix XRE-family like proteins
MKGHLHII_01524 2.6e-21 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MKGHLHII_01525 9.8e-26 K Helix-turn-helix domain
MKGHLHII_01527 4.1e-09 S Arc-like DNA binding domain
MKGHLHII_01529 1e-15 S Domain of Unknown Function with PDB structure (DUF3850)
MKGHLHII_01531 2.5e-89 M Protein of unknown function (DUF3737)
MKGHLHII_01532 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
MKGHLHII_01533 7.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
MKGHLHII_01534 7.7e-67 S SdpI/YhfL protein family
MKGHLHII_01535 7.5e-132 K Transcriptional regulatory protein, C terminal
MKGHLHII_01536 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
MKGHLHII_01537 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MKGHLHII_01538 1.1e-104 vanZ V VanZ like family
MKGHLHII_01539 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
MKGHLHII_01540 4.9e-217 EGP Major facilitator Superfamily
MKGHLHII_01541 1.7e-195 ampC V Beta-lactamase
MKGHLHII_01544 8.4e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MKGHLHII_01545 1.7e-113 tdk 2.7.1.21 F thymidine kinase
MKGHLHII_01546 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MKGHLHII_01547 4.8e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MKGHLHII_01548 1.9e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MKGHLHII_01549 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MKGHLHII_01550 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
MKGHLHII_01551 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKGHLHII_01552 4.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MKGHLHII_01553 1.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKGHLHII_01554 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MKGHLHII_01555 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKGHLHII_01556 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MKGHLHII_01557 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MKGHLHII_01558 2e-30 ywzB S Protein of unknown function (DUF1146)
MKGHLHII_01559 1.2e-177 mbl D Cell shape determining protein MreB Mrl
MKGHLHII_01560 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MKGHLHII_01561 3.3e-33 S Protein of unknown function (DUF2969)
MKGHLHII_01562 4.7e-216 rodA D Belongs to the SEDS family
MKGHLHII_01563 1.8e-78 usp6 T universal stress protein
MKGHLHII_01564 8.4e-39
MKGHLHII_01565 6.3e-238 rarA L recombination factor protein RarA
MKGHLHII_01566 1.3e-84 yueI S Protein of unknown function (DUF1694)
MKGHLHII_01567 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MKGHLHII_01568 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MKGHLHII_01569 4.8e-213 iscS2 2.8.1.7 E Aminotransferase class V
MKGHLHII_01570 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKGHLHII_01571 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MKGHLHII_01572 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MKGHLHII_01573 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MKGHLHII_01574 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
MKGHLHII_01575 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MKGHLHII_01576 1.5e-94 S Protein of unknown function (DUF3990)
MKGHLHII_01577 6.5e-44
MKGHLHII_01579 0.0 3.6.3.8 P P-type ATPase
MKGHLHII_01580 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
MKGHLHII_01581 2.5e-52
MKGHLHII_01582 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MKGHLHII_01583 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MKGHLHII_01584 5.7e-126 S Haloacid dehalogenase-like hydrolase
MKGHLHII_01585 2.3e-108 radC L DNA repair protein
MKGHLHII_01586 2.4e-176 mreB D cell shape determining protein MreB
MKGHLHII_01587 2e-147 mreC M Involved in formation and maintenance of cell shape
MKGHLHII_01588 2.7e-94 mreD
MKGHLHII_01590 6.4e-54 S Protein of unknown function (DUF3397)
MKGHLHII_01591 6.3e-78 mraZ K Belongs to the MraZ family
MKGHLHII_01592 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MKGHLHII_01593 1.8e-54 ftsL D Cell division protein FtsL
MKGHLHII_01594 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MKGHLHII_01595 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKGHLHII_01596 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MKGHLHII_01597 6.3e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKGHLHII_01598 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MKGHLHII_01599 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MKGHLHII_01600 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MKGHLHII_01601 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MKGHLHII_01602 1.7e-45 yggT S YGGT family
MKGHLHII_01603 1.7e-148 ylmH S S4 domain protein
MKGHLHII_01604 2.8e-74 gpsB D DivIVA domain protein
MKGHLHII_01605 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MKGHLHII_01606 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
MKGHLHII_01607 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MKGHLHII_01608 6.7e-37
MKGHLHII_01609 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MKGHLHII_01610 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
MKGHLHII_01611 5.4e-56 XK27_04120 S Putative amino acid metabolism
MKGHLHII_01612 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MKGHLHII_01613 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MKGHLHII_01614 8.3e-106 S Repeat protein
MKGHLHII_01615 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MKGHLHII_01616 1.6e-294 L Nuclease-related domain
MKGHLHII_01617 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MKGHLHII_01618 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKGHLHII_01619 3.5e-32 ykzG S Belongs to the UPF0356 family
MKGHLHII_01620 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKGHLHII_01621 0.0 typA T GTP-binding protein TypA
MKGHLHII_01622 5.9e-211 ftsW D Belongs to the SEDS family
MKGHLHII_01623 8.7e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MKGHLHII_01624 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MKGHLHII_01625 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MKGHLHII_01626 2.4e-187 ylbL T Belongs to the peptidase S16 family
MKGHLHII_01627 3.1e-79 comEA L Competence protein ComEA
MKGHLHII_01628 0.0 comEC S Competence protein ComEC
MKGHLHII_01629 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
MKGHLHII_01630 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
MKGHLHII_01631 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MKGHLHII_01632 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKGHLHII_01633 1.3e-148
MKGHLHII_01634 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MKGHLHII_01635 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MKGHLHII_01636 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MKGHLHII_01637 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
MKGHLHII_01638 7.8e-39 yjeM E Amino Acid
MKGHLHII_01639 3.4e-175 yjeM E Amino Acid
MKGHLHII_01640 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MKGHLHII_01641 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
MKGHLHII_01642 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MKGHLHII_01643 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MKGHLHII_01644 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MKGHLHII_01645 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKGHLHII_01646 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MKGHLHII_01647 2.7e-216 aspC 2.6.1.1 E Aminotransferase
MKGHLHII_01648 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKGHLHII_01649 2.1e-194 pbpX1 V Beta-lactamase
MKGHLHII_01650 1.2e-299 I Protein of unknown function (DUF2974)
MKGHLHII_01651 3.6e-39 C FMN_bind
MKGHLHII_01652 1.5e-81
MKGHLHII_01653 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
MKGHLHII_01654 2e-85 alkD L DNA alkylation repair enzyme
MKGHLHII_01655 9.9e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKGHLHII_01656 6.4e-128 K UTRA domain
MKGHLHII_01657 1e-54 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MKGHLHII_01658 2.3e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
MKGHLHII_01659 1.2e-227 L Transposase
MKGHLHII_01660 1.4e-09 K FCD
MKGHLHII_01661 4.7e-26 K FCD
MKGHLHII_01662 1.6e-60 clcA P chloride
MKGHLHII_01663 8.8e-41 clcA P chloride
MKGHLHII_01664 6.9e-72
MKGHLHII_01665 7.9e-71 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKGHLHII_01666 2.4e-36 L An automated process has identified a potential problem with this gene model
MKGHLHII_01667 2e-169 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKGHLHII_01668 3.5e-70 S Domain of unknown function (DUF3284)
MKGHLHII_01669 3e-239 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKGHLHII_01670 1.5e-29 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKGHLHII_01671 3.7e-131 gmuR K UTRA
MKGHLHII_01672 1.2e-225 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKGHLHII_01673 1.5e-31 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKGHLHII_01674 3.9e-46 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKGHLHII_01675 3e-111 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKGHLHII_01676 4.6e-84 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKGHLHII_01677 1.4e-22 S CAAX protease self-immunity
MKGHLHII_01678 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
MKGHLHII_01680 1.6e-96 ybaT E Amino acid permease
MKGHLHII_01681 1.7e-07 S LPXTG cell wall anchor motif
MKGHLHII_01682 4.4e-146 S Putative ABC-transporter type IV
MKGHLHII_01683 6.3e-14 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MKGHLHII_01684 1.8e-73 C nitroreductase
MKGHLHII_01685 5.1e-11 S Domain of unknown function (DUF4767)
MKGHLHII_01686 8.4e-56 S Domain of unknown function (DUF4767)
MKGHLHII_01687 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MKGHLHII_01688 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
MKGHLHII_01689 3.2e-101 3.6.1.27 I Acid phosphatase homologues
MKGHLHII_01690 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MKGHLHII_01692 2e-178 MA20_14895 S Conserved hypothetical protein 698
MKGHLHII_01693 1.1e-83 dps P Belongs to the Dps family
MKGHLHII_01694 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
MKGHLHII_01695 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MKGHLHII_01696 1.8e-58 S Putative adhesin
MKGHLHII_01697 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
MKGHLHII_01698 2e-234 mepA V MATE efflux family protein
MKGHLHII_01699 1e-190 L Transposase and inactivated derivatives, IS30 family
MKGHLHII_01700 2.4e-10 L Psort location Cytoplasmic, score
MKGHLHII_01701 4e-89 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MKGHLHII_01702 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MKGHLHII_01703 9.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MKGHLHII_01704 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
MKGHLHII_01705 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKGHLHII_01707 4.8e-138 L An automated process has identified a potential problem with this gene model
MKGHLHII_01708 7.3e-49 S Peptidase propeptide and YPEB domain
MKGHLHII_01709 4.1e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MKGHLHII_01710 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
MKGHLHII_01711 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKGHLHII_01712 2.2e-120 lsa S ABC transporter
MKGHLHII_01713 5.6e-78 ltrA S Bacterial low temperature requirement A protein (LtrA)
MKGHLHII_01714 2.8e-119 3.6.1.55 F NUDIX domain
MKGHLHII_01715 3.9e-246 brnQ U Component of the transport system for branched-chain amino acids
MKGHLHII_01716 0.0 L Plasmid pRiA4b ORF-3-like protein
MKGHLHII_01717 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MKGHLHII_01718 2.5e-08 S Protein of unknown function (DUF3021)
MKGHLHII_01720 4.2e-63 lmrB EGP Major facilitator Superfamily
MKGHLHII_01721 2.9e-122 rbtT P Major Facilitator Superfamily
MKGHLHII_01722 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
MKGHLHII_01723 2.5e-86 K GNAT family
MKGHLHII_01724 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MKGHLHII_01726 4.3e-36
MKGHLHII_01727 6.2e-288 P ABC transporter
MKGHLHII_01728 2.3e-07 V ABC-type multidrug transport system, ATPase and permease components
MKGHLHII_01729 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
MKGHLHII_01730 1.2e-250 yifK E Amino acid permease
MKGHLHII_01731 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKGHLHII_01732 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKGHLHII_01733 0.0 aha1 P E1-E2 ATPase
MKGHLHII_01734 2.4e-175 F DNA/RNA non-specific endonuclease
MKGHLHII_01735 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
MKGHLHII_01736 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKGHLHII_01737 3.4e-73 metI P ABC transporter permease
MKGHLHII_01738 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MKGHLHII_01739 1.9e-261 frdC 1.3.5.4 C FAD binding domain
MKGHLHII_01740 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MKGHLHII_01741 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
MKGHLHII_01742 3.4e-87 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MKGHLHII_01743 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MKGHLHII_01744 1.2e-232 oppA E ABC transporter substrate-binding protein
MKGHLHII_01745 2.1e-95 oppA E ABC transporter substrate-binding protein
MKGHLHII_01746 3.2e-176 K AI-2E family transporter
MKGHLHII_01747 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
MKGHLHII_01748 4.1e-18
MKGHLHII_01749 4.1e-245 G Major Facilitator
MKGHLHII_01750 1.3e-79 E Zn peptidase
MKGHLHII_01751 1e-41 ps115 K Helix-turn-helix XRE-family like proteins
MKGHLHII_01752 5.6e-45
MKGHLHII_01753 4.5e-66 S Bacteriocin helveticin-J
MKGHLHII_01754 1.7e-66 S SLAP domain
MKGHLHII_01755 5.8e-45
MKGHLHII_01756 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
MKGHLHII_01757 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MKGHLHII_01758 1.7e-174 ABC-SBP S ABC transporter
MKGHLHII_01759 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MKGHLHII_01760 1.6e-48 P CorA-like Mg2+ transporter protein
MKGHLHII_01761 5.2e-75 P CorA-like Mg2+ transporter protein
MKGHLHII_01762 3.5e-160 yvgN C Aldo keto reductase
MKGHLHII_01763 0.0 tetP J elongation factor G
MKGHLHII_01764 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
MKGHLHII_01765 1.2e-134 EGP Major facilitator Superfamily
MKGHLHII_01767 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
MKGHLHII_01768 5.7e-272 P Sodium:sulfate symporter transmembrane region
MKGHLHII_01769 1.7e-153 ydjP I Alpha/beta hydrolase family
MKGHLHII_01770 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MKGHLHII_01771 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
MKGHLHII_01772 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
MKGHLHII_01773 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
MKGHLHII_01774 9.3e-72 yeaL S Protein of unknown function (DUF441)
MKGHLHII_01775 3.5e-21
MKGHLHII_01776 3.6e-146 cbiQ P cobalt transport
MKGHLHII_01777 0.0 ykoD P ABC transporter, ATP-binding protein
MKGHLHII_01778 1.5e-95 S UPF0397 protein
MKGHLHII_01779 2.9e-66 S Domain of unknown function DUF1828
MKGHLHII_01780 5.5e-09
MKGHLHII_01781 1.2e-44
MKGHLHII_01782 2.6e-177 citR K Putative sugar-binding domain
MKGHLHII_01783 1.2e-124 yjjP S Putative threonine/serine exporter
MKGHLHII_01784 8.2e-97 yjjP S Putative threonine/serine exporter
MKGHLHII_01786 5.9e-37 M domain protein
MKGHLHII_01787 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKGHLHII_01788 2.4e-27 prmA J Ribosomal protein L11 methyltransferase
MKGHLHII_01789 1.4e-124 prmA J Ribosomal protein L11 methyltransferase
MKGHLHII_01790 8.5e-60
MKGHLHII_01791 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKGHLHII_01792 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MKGHLHII_01793 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MKGHLHII_01794 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MKGHLHII_01795 1.2e-222 patA 2.6.1.1 E Aminotransferase
MKGHLHII_01796 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKGHLHII_01797 4.8e-34 S reductase
MKGHLHII_01798 4.4e-39 S reductase
MKGHLHII_01799 2.7e-32 S reductase
MKGHLHII_01800 1.3e-148 yxeH S hydrolase
MKGHLHII_01801 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKGHLHII_01802 1.1e-243 yfnA E Amino Acid
MKGHLHII_01803 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
MKGHLHII_01804 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MKGHLHII_01805 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MKGHLHII_01806 2.2e-292 I Acyltransferase
MKGHLHII_01807 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MKGHLHII_01808 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MKGHLHII_01809 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
MKGHLHII_01810 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MKGHLHII_01811 2.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MKGHLHII_01812 2.3e-23 S Protein of unknown function (DUF2929)
MKGHLHII_01813 0.0 dnaE 2.7.7.7 L DNA polymerase
MKGHLHII_01814 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MKGHLHII_01815 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MKGHLHII_01816 4e-167 cvfB S S1 domain
MKGHLHII_01817 2.9e-165 xerD D recombinase XerD
MKGHLHII_01818 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKGHLHII_01819 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MKGHLHII_01820 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MKGHLHII_01821 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MKGHLHII_01822 2.2e-112 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MKGHLHII_01823 2.7e-18 M Lysin motif
MKGHLHII_01824 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MKGHLHII_01825 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
MKGHLHII_01826 4.3e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MKGHLHII_01827 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKGHLHII_01828 3.9e-229 S Tetratricopeptide repeat protein
MKGHLHII_01829 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKGHLHII_01830 4.5e-94 rimL J Acetyltransferase (GNAT) domain
MKGHLHII_01831 9.7e-133 S Alpha/beta hydrolase family
MKGHLHII_01832 1.7e-36 yxaM EGP Major facilitator Superfamily
MKGHLHII_01833 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
MKGHLHII_01834 1e-79 S AAA domain
MKGHLHII_01835 3.3e-61 3.6.1.55 F NUDIX domain
MKGHLHII_01836 1.9e-138 2.4.2.3 F Phosphorylase superfamily
MKGHLHII_01837 9e-144 2.4.2.3 F Phosphorylase superfamily
MKGHLHII_01838 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
MKGHLHII_01839 9.7e-65 yagE E amino acid
MKGHLHII_01840 8.4e-128 yagE E Amino acid permease
MKGHLHII_01841 4.3e-86 3.4.21.96 S SLAP domain
MKGHLHII_01842 8.8e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKGHLHII_01843 5.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MKGHLHII_01844 1.2e-107 hlyIII S protein, hemolysin III
MKGHLHII_01845 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
MKGHLHII_01846 7.1e-36 yozE S Belongs to the UPF0346 family
MKGHLHII_01847 1.1e-66 yjcE P NhaP-type Na H and K H
MKGHLHII_01848 1.5e-40 yjcE P Sodium proton antiporter
MKGHLHII_01849 1.9e-94 yjcE P Sodium proton antiporter
MKGHLHII_01850 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKGHLHII_01851 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKGHLHII_01852 5.8e-152 dprA LU DNA protecting protein DprA
MKGHLHII_01853 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKGHLHII_01854 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MKGHLHII_01855 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
MKGHLHII_01856 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MKGHLHII_01857 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MKGHLHII_01858 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
MKGHLHII_01859 1.4e-86 C Aldo keto reductase
MKGHLHII_01860 1.4e-95 sip L Belongs to the 'phage' integrase family
MKGHLHII_01863 1.8e-16 S protein disulfide oxidoreductase activity
MKGHLHII_01864 6.6e-11 K Helix-turn-helix XRE-family like proteins
MKGHLHII_01867 3.2e-10
MKGHLHII_01871 8.9e-55 S Protein of unknown function (DUF1351)
MKGHLHII_01872 1.9e-45 S ERF superfamily
MKGHLHII_01873 1.1e-23 K Conserved phage C-terminus (Phg_2220_C)
MKGHLHII_01874 6.4e-17 K Transcriptional regulator
MKGHLHII_01876 8.1e-108 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MKGHLHII_01877 1.5e-21 radC L DNA repair protein
MKGHLHII_01886 5.2e-69 S ORF6C domain
MKGHLHII_01888 6.2e-37 S VRR_NUC
MKGHLHII_01889 1.1e-133 xerD L Phage integrase, N-terminal SAM-like domain
MKGHLHII_01890 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKGHLHII_01891 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKGHLHII_01892 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MKGHLHII_01893 1.4e-115 mmuP E amino acid
MKGHLHII_01894 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
MKGHLHII_01895 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
MKGHLHII_01896 1.7e-284 E Amino acid permease
MKGHLHII_01897 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MKGHLHII_01898 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
MKGHLHII_01899 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MKGHLHII_01900 2.4e-36 L An automated process has identified a potential problem with this gene model
MKGHLHII_01901 1.1e-63
MKGHLHII_01902 1.6e-73 marR K Transcriptional regulator, MarR family
MKGHLHII_01903 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MKGHLHII_01904 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKGHLHII_01905 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKGHLHII_01906 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKGHLHII_01907 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MKGHLHII_01908 2.9e-107 IQ reductase
MKGHLHII_01909 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKGHLHII_01910 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MKGHLHII_01911 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MKGHLHII_01912 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MKGHLHII_01913 3.3e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MKGHLHII_01914 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MKGHLHII_01915 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MKGHLHII_01916 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MKGHLHII_01917 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKGHLHII_01920 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
MKGHLHII_01921 1.3e-273 E amino acid
MKGHLHII_01922 0.0 L Helicase C-terminal domain protein
MKGHLHII_01923 2.9e-81 C Flavodoxin
MKGHLHII_01924 1.4e-72 uvrA3 L excinuclease ABC, A subunit
MKGHLHII_01925 0.0 uvrA3 L excinuclease ABC, A subunit
MKGHLHII_01926 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MKGHLHII_01927 2.1e-114 3.6.1.27 I Acid phosphatase homologues
MKGHLHII_01928 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
MKGHLHII_01929 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKGHLHII_01930 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
MKGHLHII_01931 9.3e-204 pbpX1 V Beta-lactamase
MKGHLHII_01932 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MKGHLHII_01933 1.3e-94 S ECF-type riboflavin transporter, S component
MKGHLHII_01934 1.3e-229 S Putative peptidoglycan binding domain
MKGHLHII_01935 9e-83 K Acetyltransferase (GNAT) domain
MKGHLHII_01936 1.7e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MKGHLHII_01937 2.5e-191 yrvN L AAA C-terminal domain
MKGHLHII_01938 5.7e-65 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MKGHLHII_01939 6.8e-153 treB G phosphotransferase system
MKGHLHII_01940 4.5e-111 treB G phosphotransferase system
MKGHLHII_01941 1.2e-100 treR K UTRA
MKGHLHII_01942 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MKGHLHII_01943 5.7e-18
MKGHLHII_01944 1.5e-239 G Bacterial extracellular solute-binding protein
MKGHLHII_01945 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
MKGHLHII_01946 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
MKGHLHII_01948 0.0 S SLAP domain
MKGHLHII_01949 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
MKGHLHII_01950 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
MKGHLHII_01951 3.4e-42 S RloB-like protein
MKGHLHII_01952 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
MKGHLHII_01953 2.3e-51 3.1.21.3 V Type I restriction modification DNA specificity domain
MKGHLHII_01954 8.3e-45 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MKGHLHII_01955 1.2e-63 S SIR2-like domain
MKGHLHII_01956 3.2e-10 S Domain of unknown function DUF87
MKGHLHII_01957 1.6e-35 S cog cog0433
MKGHLHII_01958 1.9e-110 F DNA/RNA non-specific endonuclease
MKGHLHII_01959 2.7e-34 S YSIRK type signal peptide
MKGHLHII_01961 5.5e-53
MKGHLHII_01962 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MKGHLHII_01963 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MKGHLHII_01964 9.6e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MKGHLHII_01965 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MKGHLHII_01966 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
MKGHLHII_01967 0.0 FbpA K Fibronectin-binding protein
MKGHLHII_01968 1.1e-66
MKGHLHII_01969 1.3e-159 degV S EDD domain protein, DegV family
MKGHLHII_01970 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MKGHLHII_01971 5.4e-203 xerS L Belongs to the 'phage' integrase family
MKGHLHII_01972 4.1e-67
MKGHLHII_01973 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
MKGHLHII_01974 5.8e-211 M Glycosyl hydrolases family 25
MKGHLHII_01975 6.9e-122 yoaK S Protein of unknown function (DUF1275)
MKGHLHII_01976 1.3e-29 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MKGHLHII_01977 4.6e-13 L TIGRFAM transposase, IS605 OrfB family
MKGHLHII_01978 1.2e-11 S Transposase C of IS166 homeodomain
MKGHLHII_01979 1.4e-59 XK27_01125 L IS66 Orf2 like protein
MKGHLHII_01981 4.4e-169 ppaC 3.6.1.1 C inorganic pyrophosphatase
MKGHLHII_01982 2.8e-182 K Transcriptional regulator
MKGHLHII_01983 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKGHLHII_01984 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKGHLHII_01985 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MKGHLHII_01986 0.0 snf 2.7.11.1 KL domain protein
MKGHLHII_01987 2e-35
MKGHLHII_01989 3.8e-104 pncA Q Isochorismatase family
MKGHLHII_01990 4.9e-118
MKGHLHII_01993 4e-62
MKGHLHII_01994 1.4e-34
MKGHLHII_01995 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
MKGHLHII_01996 3.4e-79
MKGHLHII_01997 1e-242 cpdA S Calcineurin-like phosphoesterase
MKGHLHII_01998 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MKGHLHII_01999 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MKGHLHII_02000 1e-107 ypsA S Belongs to the UPF0398 family
MKGHLHII_02001 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MKGHLHII_02002 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MKGHLHII_02003 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKGHLHII_02004 1.3e-114 dnaD L DnaD domain protein
MKGHLHII_02005 5.8e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MKGHLHII_02006 2.4e-89 ypmB S Protein conserved in bacteria
MKGHLHII_02007 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MKGHLHII_02008 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MKGHLHII_02009 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MKGHLHII_02010 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
MKGHLHII_02011 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MKGHLHII_02012 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MKGHLHII_02013 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MKGHLHII_02014 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
MKGHLHII_02015 9.2e-250 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
MKGHLHII_02016 9.7e-169
MKGHLHII_02017 7.5e-143
MKGHLHII_02018 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MKGHLHII_02019 1.4e-26
MKGHLHII_02020 6.7e-145
MKGHLHII_02021 5.1e-137
MKGHLHII_02022 4.5e-141
MKGHLHII_02023 9.6e-124 skfE V ATPases associated with a variety of cellular activities
MKGHLHII_02024 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
MKGHLHII_02025 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MKGHLHII_02026 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MKGHLHII_02027 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
MKGHLHII_02028 4.8e-81 mutT 3.6.1.55 F NUDIX domain
MKGHLHII_02029 1.4e-127 S Peptidase family M23
MKGHLHII_02030 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MKGHLHII_02031 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MKGHLHII_02032 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MKGHLHII_02033 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MKGHLHII_02034 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
MKGHLHII_02035 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MKGHLHII_02036 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MKGHLHII_02037 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
MKGHLHII_02038 3.5e-71 yqeY S YqeY-like protein
MKGHLHII_02039 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MKGHLHII_02040 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MKGHLHII_02041 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
MKGHLHII_02042 1.3e-116 S Peptidase family M23
MKGHLHII_02043 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKGHLHII_02045 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKGHLHII_02046 1.1e-34
MKGHLHII_02047 4.8e-205 pbpX1 V Beta-lactamase
MKGHLHII_02048 5.1e-226 N Uncharacterized conserved protein (DUF2075)
MKGHLHII_02049 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MKGHLHII_02050 4.3e-58
MKGHLHII_02051 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MKGHLHII_02052 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MKGHLHII_02053 2.6e-280 thrC 4.2.3.1 E Threonine synthase
MKGHLHII_02054 4.4e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
MKGHLHII_02055 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
MKGHLHII_02056 0.0 L PLD-like domain
MKGHLHII_02057 4.8e-42 S SnoaL-like domain
MKGHLHII_02058 5.4e-53 hipB K sequence-specific DNA binding
MKGHLHII_02059 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
MKGHLHII_02060 3.4e-27
MKGHLHII_02061 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
MKGHLHII_02062 2.6e-275 V ABC-type multidrug transport system, ATPase and permease components
MKGHLHII_02063 1e-84 L Transposase
MKGHLHII_02064 1.4e-94
MKGHLHII_02065 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
MKGHLHII_02066 9e-98
MKGHLHII_02067 4.9e-108 K LysR substrate binding domain
MKGHLHII_02068 1e-20
MKGHLHII_02069 2.3e-215 S Sterol carrier protein domain
MKGHLHII_02070 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MKGHLHII_02071 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
MKGHLHII_02072 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MKGHLHII_02073 5.7e-233 arcA 3.5.3.6 E Arginine
MKGHLHII_02074 9e-137 lysR5 K LysR substrate binding domain
MKGHLHII_02075 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
MKGHLHII_02076 1e-48 S Metal binding domain of Ada
MKGHLHII_02077 2.3e-43 ybhL S Belongs to the BI1 family
MKGHLHII_02078 1.2e-210 S Bacterial protein of unknown function (DUF871)
MKGHLHII_02079 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKGHLHII_02080 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MKGHLHII_02081 1.5e-102 srtA 3.4.22.70 M sortase family
MKGHLHII_02082 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MKGHLHII_02083 4.9e-40 L Transposase and inactivated derivatives, IS30 family
MKGHLHII_02084 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MKGHLHII_02085 0.0 dnaK O Heat shock 70 kDa protein
MKGHLHII_02086 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MKGHLHII_02087 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MKGHLHII_02088 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MKGHLHII_02089 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MKGHLHII_02090 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MKGHLHII_02091 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MKGHLHII_02092 3.2e-47 rplGA J ribosomal protein
MKGHLHII_02093 8.8e-47 ylxR K Protein of unknown function (DUF448)
MKGHLHII_02094 1.4e-196 nusA K Participates in both transcription termination and antitermination
MKGHLHII_02095 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
MKGHLHII_02096 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKGHLHII_02097 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MKGHLHII_02098 1.3e-195 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MKGHLHII_02099 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
MKGHLHII_02100 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKGHLHII_02101 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MKGHLHII_02102 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MKGHLHII_02103 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MKGHLHII_02104 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
MKGHLHII_02105 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
MKGHLHII_02106 2.9e-116 plsC 2.3.1.51 I Acyltransferase
MKGHLHII_02107 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MKGHLHII_02108 0.0 pepO 3.4.24.71 O Peptidase family M13
MKGHLHII_02109 0.0 mdlB V ABC transporter
MKGHLHII_02110 0.0 mdlA V ABC transporter
MKGHLHII_02111 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
MKGHLHII_02112 3e-38 ynzC S UPF0291 protein
MKGHLHII_02113 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKGHLHII_02114 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
MKGHLHII_02115 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
MKGHLHII_02116 4.6e-213 S SLAP domain
MKGHLHII_02117 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MKGHLHII_02118 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MKGHLHII_02119 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MKGHLHII_02120 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MKGHLHII_02121 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKGHLHII_02122 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MKGHLHII_02123 2.7e-258 yfnA E amino acid
MKGHLHII_02124 0.0 V FtsX-like permease family
MKGHLHII_02125 4.1e-133 cysA V ABC transporter, ATP-binding protein
MKGHLHII_02126 3.4e-23
MKGHLHII_02128 2.5e-288 pipD E Dipeptidase
MKGHLHII_02129 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MKGHLHII_02130 0.0 smc D Required for chromosome condensation and partitioning
MKGHLHII_02131 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MKGHLHII_02132 2.1e-308 oppA E ABC transporter substrate-binding protein
MKGHLHII_02133 3.1e-240 oppA E ABC transporter substrate-binding protein
MKGHLHII_02134 9.7e-46 oppA E ABC transporter substrate-binding protein
MKGHLHII_02135 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
MKGHLHII_02136 2.6e-172 oppB P ABC transporter permease
MKGHLHII_02137 1.5e-170 oppF P Belongs to the ABC transporter superfamily
MKGHLHII_02138 1.1e-192 oppD P Belongs to the ABC transporter superfamily
MKGHLHII_02139 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKGHLHII_02140 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MKGHLHII_02141 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MKGHLHII_02142 7.6e-305 yloV S DAK2 domain fusion protein YloV
MKGHLHII_02143 4e-57 asp S Asp23 family, cell envelope-related function
MKGHLHII_02144 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MKGHLHII_02146 1.8e-87 M hydrolase, family 25
MKGHLHII_02147 7.6e-39 S Bacteriophage holin of superfamily 6 (Holin_LLH)
MKGHLHII_02156 6e-136 S Phage minor structural protein
MKGHLHII_02157 4.5e-34 S phage tail
MKGHLHII_02158 2e-127 M Phage tail tape measure protein TP901
MKGHLHII_02161 3.1e-13 S Pfam:Phage_TTP_1
MKGHLHII_02163 8.6e-14 S Bacteriophage HK97-gp10, putative tail-component
MKGHLHII_02165 5.2e-17 S Phage gp6-like head-tail connector protein
MKGHLHII_02166 2e-55 S Phage capsid family
MKGHLHII_02167 5.5e-87 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MKGHLHII_02168 9.1e-135 S Phage portal protein
MKGHLHII_02170 2.8e-210 S Phage Terminase
MKGHLHII_02171 9e-47 S HicB_like antitoxin of bacterial toxin-antitoxin system
MKGHLHII_02172 3.4e-18 N HicA toxin of bacterial toxin-antitoxin,
MKGHLHII_02173 1.6e-55 L Phage terminase, small subunit
MKGHLHII_02174 3.9e-33 L HNH nucleases
MKGHLHII_02176 3.1e-14 arpU S Phage transcriptional regulator, ArpU family
MKGHLHII_02177 9.8e-12
MKGHLHII_02179 3.3e-37 S VRR_NUC
MKGHLHII_02182 4.5e-24 L Belongs to the 'phage' integrase family
MKGHLHII_02183 1.4e-30
MKGHLHII_02184 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
MKGHLHII_02185 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MKGHLHII_02186 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MKGHLHII_02187 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MKGHLHII_02188 1.1e-138 stp 3.1.3.16 T phosphatase
MKGHLHII_02189 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKGHLHII_02190 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MKGHLHII_02191 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKGHLHII_02192 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MKGHLHII_02193 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MKGHLHII_02194 1.1e-77 6.3.3.2 S ASCH
MKGHLHII_02195 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
MKGHLHII_02196 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MKGHLHII_02197 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MKGHLHII_02198 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKGHLHII_02199 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKGHLHII_02200 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MKGHLHII_02201 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKGHLHII_02202 3.4e-71 yqhY S Asp23 family, cell envelope-related function
MKGHLHII_02203 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKGHLHII_02204 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MKGHLHII_02205 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MKGHLHII_02206 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MKGHLHII_02207 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKGHLHII_02208 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
MKGHLHII_02210 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MKGHLHII_02211 4.3e-298 S Predicted membrane protein (DUF2207)
MKGHLHII_02212 7.6e-155 cinI S Serine hydrolase (FSH1)
MKGHLHII_02213 1e-205 M Glycosyl hydrolases family 25
MKGHLHII_02215 8.5e-178 I Carboxylesterase family
MKGHLHII_02216 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
MKGHLHII_02217 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
MKGHLHII_02218 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
MKGHLHII_02219 1.7e-148 S haloacid dehalogenase-like hydrolase
MKGHLHII_02220 7e-50
MKGHLHII_02221 1.9e-37
MKGHLHII_02222 1.2e-63 S Alpha beta hydrolase
MKGHLHII_02223 3.7e-19 S Alpha beta hydrolase
MKGHLHII_02224 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MKGHLHII_02225 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MKGHLHII_02226 7.1e-46
MKGHLHII_02227 3.1e-148 glcU U sugar transport
MKGHLHII_02228 3.7e-250 lctP C L-lactate permease
MKGHLHII_02229 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MKGHLHII_02230 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MKGHLHII_02231 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MKGHLHII_02232 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MKGHLHII_02233 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MKGHLHII_02234 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MKGHLHII_02235 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MKGHLHII_02236 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKGHLHII_02237 1.5e-102 GM NmrA-like family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)