ORF_ID e_value Gene_name EC_number CAZy COGs Description
LCDLCALC_00001 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LCDLCALC_00002 9.5e-31
LCDLCALC_00003 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LCDLCALC_00004 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LCDLCALC_00005 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LCDLCALC_00006 1.2e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LCDLCALC_00007 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LCDLCALC_00008 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
LCDLCALC_00009 1.6e-244 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LCDLCALC_00010 4.2e-182 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LCDLCALC_00011 2.6e-35 yaaA S S4 domain protein YaaA
LCDLCALC_00012 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LCDLCALC_00013 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCDLCALC_00014 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCDLCALC_00015 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
LCDLCALC_00016 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LCDLCALC_00017 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LCDLCALC_00018 7.3e-148 S Protein of unknown function (DUF805)
LCDLCALC_00019 3.4e-135 glnQ E ABC transporter, ATP-binding protein
LCDLCALC_00020 6.7e-290 glnP P ABC transporter permease
LCDLCALC_00021 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LCDLCALC_00022 5.8e-64 yeaO S Protein of unknown function, DUF488
LCDLCALC_00023 1.3e-124 terC P Integral membrane protein TerC family
LCDLCALC_00024 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
LCDLCALC_00025 8.5e-133 cobB K SIR2 family
LCDLCALC_00026 2.2e-113 S SLAP domain
LCDLCALC_00027 2.6e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
LCDLCALC_00028 5.7e-46 S An automated process has identified a potential problem with this gene model
LCDLCALC_00029 3e-137 S Protein of unknown function (DUF3100)
LCDLCALC_00030 4e-245 3.5.1.47 S Peptidase dimerisation domain
LCDLCALC_00031 5.8e-230 Q Imidazolonepropionase and related amidohydrolases
LCDLCALC_00032 0.0 oppA E ABC transporter
LCDLCALC_00033 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
LCDLCALC_00034 0.0 mco Q Multicopper oxidase
LCDLCALC_00035 1.9e-25
LCDLCALC_00036 1.9e-158 metQ1 P Belongs to the nlpA lipoprotein family
LCDLCALC_00037 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
LCDLCALC_00038 2.4e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LCDLCALC_00039 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LCDLCALC_00040 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LCDLCALC_00041 1.9e-89 ydiM G Major facilitator superfamily
LCDLCALC_00042 1.2e-57 L Transposase
LCDLCALC_00043 8.1e-91 cjaA ET ABC transporter substrate-binding protein
LCDLCALC_00044 3e-53 cjaA ET ABC transporter substrate-binding protein
LCDLCALC_00045 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LCDLCALC_00046 2e-110 P ABC transporter permease
LCDLCALC_00047 9.6e-110 papP P ABC transporter, permease protein
LCDLCALC_00049 8.8e-62 yodB K Transcriptional regulator, HxlR family
LCDLCALC_00050 3.8e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCDLCALC_00051 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LCDLCALC_00052 2.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LCDLCALC_00053 1.5e-72 S Aminoacyl-tRNA editing domain
LCDLCALC_00054 1.2e-54 S Abi-like protein
LCDLCALC_00055 8e-224 S SLAP domain
LCDLCALC_00056 3.9e-128 S CAAX protease self-immunity
LCDLCALC_00057 1.3e-277 arlS 2.7.13.3 T Histidine kinase
LCDLCALC_00058 1.2e-126 K response regulator
LCDLCALC_00059 4.7e-97 yceD S Uncharacterized ACR, COG1399
LCDLCALC_00060 1.7e-215 ylbM S Belongs to the UPF0348 family
LCDLCALC_00061 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LCDLCALC_00062 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
LCDLCALC_00063 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LCDLCALC_00064 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
LCDLCALC_00065 4.2e-84 yqeG S HAD phosphatase, family IIIA
LCDLCALC_00066 9.2e-201 tnpB L Putative transposase DNA-binding domain
LCDLCALC_00067 6.9e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LCDLCALC_00068 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LCDLCALC_00069 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LCDLCALC_00070 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LCDLCALC_00071 4e-98 rihB 3.2.2.1 F Nucleoside
LCDLCALC_00072 3.7e-101 potB E Binding-protein-dependent transport system inner membrane component
LCDLCALC_00073 3.9e-23 S domain protein
LCDLCALC_00074 1.7e-168 V ABC transporter
LCDLCALC_00075 7.7e-39 S Protein of unknown function (DUF3021)
LCDLCALC_00076 4.2e-53 K LytTr DNA-binding domain
LCDLCALC_00079 3e-107 L Transposase
LCDLCALC_00080 1.3e-96 L Transposase
LCDLCALC_00081 4.3e-75
LCDLCALC_00082 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LCDLCALC_00083 1.3e-168 dnaI L Primosomal protein DnaI
LCDLCALC_00084 5.1e-251 dnaB L Replication initiation and membrane attachment
LCDLCALC_00085 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LCDLCALC_00086 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LCDLCALC_00087 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LCDLCALC_00088 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCDLCALC_00089 3.5e-25 qmcA O prohibitin homologues
LCDLCALC_00090 7.4e-105 qmcA O prohibitin homologues
LCDLCALC_00091 8e-51 L RelB antitoxin
LCDLCALC_00092 4.5e-188 S Bacteriocin helveticin-J
LCDLCALC_00093 4.4e-283 M Peptidase family M1 domain
LCDLCALC_00094 1.8e-176 S SLAP domain
LCDLCALC_00095 6.9e-218 mepA V MATE efflux family protein
LCDLCALC_00096 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LCDLCALC_00097 1.7e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LCDLCALC_00098 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LCDLCALC_00100 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LCDLCALC_00101 6.5e-221 ecsB U ABC transporter
LCDLCALC_00102 5.7e-135 ecsA V ABC transporter, ATP-binding protein
LCDLCALC_00103 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
LCDLCALC_00104 3.9e-25
LCDLCALC_00105 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LCDLCALC_00106 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
LCDLCALC_00107 1.1e-265
LCDLCALC_00108 2.4e-51 S Domain of unknown function DUF1829
LCDLCALC_00109 2.9e-23
LCDLCALC_00110 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
LCDLCALC_00111 0.0 L AAA domain
LCDLCALC_00112 1e-226 yhaO L Ser Thr phosphatase family protein
LCDLCALC_00113 8e-55 yheA S Belongs to the UPF0342 family
LCDLCALC_00114 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LCDLCALC_00115 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LCDLCALC_00116 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
LCDLCALC_00117 7.5e-103 G Phosphoglycerate mutase family
LCDLCALC_00118 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
LCDLCALC_00120 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
LCDLCALC_00121 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
LCDLCALC_00122 5.6e-179 S PFAM Archaeal ATPase
LCDLCALC_00123 2.4e-73 S cog cog1373
LCDLCALC_00124 2.4e-128 S cog cog1373
LCDLCALC_00125 1.4e-109 yniG EGP Major facilitator Superfamily
LCDLCALC_00126 5.4e-237 L transposase, IS605 OrfB family
LCDLCALC_00127 4.5e-76 yniG EGP Major facilitator Superfamily
LCDLCALC_00128 4.9e-35
LCDLCALC_00130 1.3e-42
LCDLCALC_00131 1.9e-75 M LysM domain
LCDLCALC_00132 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
LCDLCALC_00133 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LCDLCALC_00134 6.7e-98 M ErfK YbiS YcfS YnhG
LCDLCALC_00135 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LCDLCALC_00136 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LCDLCALC_00138 4.7e-46 pspC KT PspC domain
LCDLCALC_00139 2.6e-198 L COG2963 Transposase and inactivated derivatives
LCDLCALC_00140 7.9e-26 L COG2963 Transposase and inactivated derivatives
LCDLCALC_00141 1.1e-282 phoR 2.7.13.3 T Histidine kinase
LCDLCALC_00142 4.3e-121 T Transcriptional regulatory protein, C terminal
LCDLCALC_00143 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
LCDLCALC_00144 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LCDLCALC_00145 1.2e-152 pstA P Phosphate transport system permease protein PstA
LCDLCALC_00146 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
LCDLCALC_00147 4.2e-145 pstS P Phosphate
LCDLCALC_00148 1.3e-30
LCDLCALC_00149 6.3e-192 oppA E ABC transporter, substratebinding protein
LCDLCALC_00150 4.7e-275 ytgP S Polysaccharide biosynthesis protein
LCDLCALC_00151 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LCDLCALC_00152 1.1e-121 3.6.1.27 I Acid phosphatase homologues
LCDLCALC_00153 2.8e-168 K LysR substrate binding domain
LCDLCALC_00154 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LCDLCALC_00155 6.2e-43 1.3.5.4 C FAD binding domain
LCDLCALC_00156 2.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
LCDLCALC_00157 1.1e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
LCDLCALC_00158 3.6e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LCDLCALC_00159 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LCDLCALC_00160 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LCDLCALC_00161 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LCDLCALC_00162 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
LCDLCALC_00163 7.9e-238 cydA 1.10.3.14 C ubiquinol oxidase
LCDLCALC_00164 9.3e-86
LCDLCALC_00165 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCDLCALC_00166 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
LCDLCALC_00167 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LCDLCALC_00168 7e-23 cydA 1.10.3.14 C ubiquinol oxidase
LCDLCALC_00169 3.7e-130 ybbH_2 K rpiR family
LCDLCALC_00170 1.8e-195 S Bacterial protein of unknown function (DUF871)
LCDLCALC_00171 4.1e-214 2.7.1.208, 2.7.1.211 G phosphotransferase system
LCDLCALC_00172 1.8e-119 S Putative esterase
LCDLCALC_00173 3.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LCDLCALC_00174 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
LCDLCALC_00176 8e-129 qacA EGP Major facilitator Superfamily
LCDLCALC_00177 6.8e-10
LCDLCALC_00179 7.6e-102 M hydrolase, family 25
LCDLCALC_00180 4e-38 S Bacteriophage holin of superfamily 6 (Holin_LLH)
LCDLCALC_00187 7.7e-07 S Domain of unknown function (DUF2479)
LCDLCALC_00189 7.6e-131 S Phage minor structural protein
LCDLCALC_00190 1.2e-34 S phage tail
LCDLCALC_00191 1.6e-129 M Phage tail tape measure protein TP901
LCDLCALC_00194 1.2e-12 S Pfam:Phage_TTP_1
LCDLCALC_00196 2.8e-12 S Bacteriophage HK97-gp10, putative tail-component
LCDLCALC_00198 5.5e-19 S Phage gp6-like head-tail connector protein
LCDLCALC_00199 1.6e-52 S peptidase activity
LCDLCALC_00200 1.9e-87 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
LCDLCALC_00201 2.2e-133 S Phage portal protein
LCDLCALC_00203 1.7e-212 S Phage Terminase
LCDLCALC_00205 4.2e-56 S Phage terminase, small subunit
LCDLCALC_00206 1.5e-42 S HNH endonuclease
LCDLCALC_00207 3.4e-18
LCDLCALC_00209 3.3e-37 S VRR_NUC
LCDLCALC_00220 2.7e-268 S Phage plasmid primase, P4
LCDLCALC_00221 1.3e-30 S Protein of unknown function (DUF669)
LCDLCALC_00222 4.7e-148 res L Helicase C-terminal domain protein
LCDLCALC_00224 6.1e-70 S AAA domain
LCDLCALC_00225 5e-30 S HNH endonuclease
LCDLCALC_00231 1.4e-14
LCDLCALC_00232 4e-75 S Phage antirepressor protein KilAC domain
LCDLCALC_00233 6.5e-17 K Helix-turn-helix XRE-family like proteins
LCDLCALC_00234 1.4e-16
LCDLCALC_00237 7.1e-19 ps115 K sequence-specific DNA binding
LCDLCALC_00238 7.4e-20 S Pfam:Peptidase_M78
LCDLCALC_00239 8.5e-24 S Hypothetical protein (DUF2513)
LCDLCALC_00242 6.1e-131 sip L Belongs to the 'phage' integrase family
LCDLCALC_00243 4.5e-121 qacA EGP Major facilitator Superfamily
LCDLCALC_00244 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LCDLCALC_00247 4e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
LCDLCALC_00248 2.5e-35 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
LCDLCALC_00249 5.9e-24
LCDLCALC_00250 3.4e-176 M Glycosyl hydrolases family 25
LCDLCALC_00251 8e-27
LCDLCALC_00252 7e-16
LCDLCALC_00254 1.7e-16
LCDLCALC_00256 1.2e-10
LCDLCALC_00261 6.4e-70
LCDLCALC_00262 3.4e-35
LCDLCALC_00263 3.2e-09
LCDLCALC_00264 2e-113 Z012_12235 S Baseplate J-like protein
LCDLCALC_00265 1.4e-30
LCDLCALC_00266 8.3e-39
LCDLCALC_00267 5.1e-103
LCDLCALC_00268 2.7e-46
LCDLCALC_00269 6.5e-59 M LysM domain
LCDLCALC_00270 2.3e-195 M Phage tail tape measure protein TP901
LCDLCALC_00271 1.1e-11
LCDLCALC_00272 1.8e-11
LCDLCALC_00273 1.7e-133 Z012_02110 S Protein of unknown function (DUF3383)
LCDLCALC_00274 1.6e-27
LCDLCALC_00275 2.7e-10
LCDLCALC_00276 7.7e-42
LCDLCALC_00277 1.6e-27 S Protein of unknown function (DUF4054)
LCDLCALC_00278 7.7e-37 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
LCDLCALC_00279 2.6e-23
LCDLCALC_00280 1.3e-53 S Uncharacterized protein conserved in bacteria (DUF2213)
LCDLCALC_00281 4.8e-20 S Lysin motif
LCDLCALC_00282 9.6e-56 S Phage Mu protein F like protein
LCDLCALC_00283 5.6e-91 S Protein of unknown function (DUF1073)
LCDLCALC_00284 6.1e-181 S Terminase-like family
LCDLCALC_00287 9.2e-156 2.1.1.72 KL DNA methylase
LCDLCALC_00292 5.5e-09
LCDLCALC_00294 1e-10 S VRR_NUC
LCDLCALC_00296 4e-69 S ORF6C domain
LCDLCALC_00301 2.7e-33 Q DNA (cytosine-5-)-methyltransferase activity
LCDLCALC_00307 2.6e-21 radC L DNA repair protein
LCDLCALC_00309 8.7e-20 K transcriptional
LCDLCALC_00310 2.6e-23 K Conserved phage C-terminus (Phg_2220_C)
LCDLCALC_00311 1.6e-44 S ERF superfamily
LCDLCALC_00312 9.9e-54 S Protein of unknown function (DUF1351)
LCDLCALC_00317 3.5e-09
LCDLCALC_00319 4e-24 S Domain of unknown function (DUF771)
LCDLCALC_00320 4.1e-15 K Helix-turn-helix XRE-family like proteins
LCDLCALC_00321 2.6e-18 K Helix-turn-helix XRE-family like proteins
LCDLCALC_00322 1e-30 S cog cog1373
LCDLCALC_00323 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
LCDLCALC_00324 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
LCDLCALC_00325 1.8e-163
LCDLCALC_00326 7.8e-26 K Acetyltransferase (GNAT) domain
LCDLCALC_00328 0.0 ydgH S MMPL family
LCDLCALC_00329 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
LCDLCALC_00330 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
LCDLCALC_00331 1.8e-154 corA P CorA-like Mg2+ transporter protein
LCDLCALC_00332 6.7e-240 G Bacterial extracellular solute-binding protein
LCDLCALC_00333 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
LCDLCALC_00334 1.8e-145 gtsC P Binding-protein-dependent transport system inner membrane component
LCDLCALC_00335 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
LCDLCALC_00336 1.9e-203 malK P ATPases associated with a variety of cellular activities
LCDLCALC_00337 3.8e-281 pipD E Dipeptidase
LCDLCALC_00338 1.9e-158 endA F DNA RNA non-specific endonuclease
LCDLCALC_00339 8e-182 dnaQ 2.7.7.7 L EXOIII
LCDLCALC_00340 7.6e-157 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LCDLCALC_00341 3e-116 yviA S Protein of unknown function (DUF421)
LCDLCALC_00342 1.1e-56 S Protein of unknown function (DUF3290)
LCDLCALC_00344 3.8e-139 pnuC H nicotinamide mononucleotide transporter
LCDLCALC_00345 4e-08
LCDLCALC_00346 6.6e-56
LCDLCALC_00347 2.7e-57
LCDLCALC_00348 1.6e-11
LCDLCALC_00349 8.1e-126 S PAS domain
LCDLCALC_00350 2.9e-277 V ABC transporter transmembrane region
LCDLCALC_00351 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
LCDLCALC_00352 3.1e-130 T Transcriptional regulatory protein, C terminal
LCDLCALC_00353 5.2e-187 T GHKL domain
LCDLCALC_00354 3.4e-76 S Peptidase propeptide and YPEB domain
LCDLCALC_00355 2.5e-72 S Peptidase propeptide and YPEB domain
LCDLCALC_00356 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
LCDLCALC_00357 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
LCDLCALC_00358 7e-68 V ABC transporter transmembrane region
LCDLCALC_00359 9e-161 V ABC transporter transmembrane region
LCDLCALC_00360 2.3e-309 oppA3 E ABC transporter, substratebinding protein
LCDLCALC_00361 2.4e-60 ypaA S Protein of unknown function (DUF1304)
LCDLCALC_00362 2.1e-28 S Peptidase propeptide and YPEB domain
LCDLCALC_00363 7.1e-237 L transposase, IS605 OrfB family
LCDLCALC_00364 8.8e-58 S Peptidase propeptide and YPEB domain
LCDLCALC_00365 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LCDLCALC_00366 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
LCDLCALC_00367 7.1e-98 E GDSL-like Lipase/Acylhydrolase
LCDLCALC_00368 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
LCDLCALC_00369 1.6e-143 aatB ET ABC transporter substrate-binding protein
LCDLCALC_00370 1e-105 glnQ 3.6.3.21 E ABC transporter
LCDLCALC_00371 1.5e-107 glnP P ABC transporter permease
LCDLCALC_00372 0.0 helD 3.6.4.12 L DNA helicase
LCDLCALC_00373 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
LCDLCALC_00374 1.4e-126 pgm3 G Phosphoglycerate mutase family
LCDLCALC_00375 4.4e-140 ypuA S Protein of unknown function (DUF1002)
LCDLCALC_00376 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
LCDLCALC_00377 3.7e-122 S Alpha/beta hydrolase family
LCDLCALC_00378 1.4e-140 L An automated process has identified a potential problem with this gene model
LCDLCALC_00379 5.6e-36
LCDLCALC_00380 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCDLCALC_00381 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
LCDLCALC_00382 2.8e-135
LCDLCALC_00383 1.3e-258 glnPH2 P ABC transporter permease
LCDLCALC_00384 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LCDLCALC_00385 6.4e-224 S Cysteine-rich secretory protein family
LCDLCALC_00386 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LCDLCALC_00387 1.4e-112
LCDLCALC_00388 6.3e-202 yibE S overlaps another CDS with the same product name
LCDLCALC_00389 4.9e-129 yibF S overlaps another CDS with the same product name
LCDLCALC_00390 2.5e-144 I alpha/beta hydrolase fold
LCDLCALC_00391 0.0 G Belongs to the glycosyl hydrolase 31 family
LCDLCALC_00392 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LCDLCALC_00393 1.2e-241 S response to antibiotic
LCDLCALC_00394 4.9e-125
LCDLCALC_00395 0.0 3.6.3.8 P P-type ATPase
LCDLCALC_00396 8.7e-66 2.7.1.191 G PTS system fructose IIA component
LCDLCALC_00397 4.4e-43
LCDLCALC_00398 5.9e-09
LCDLCALC_00399 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
LCDLCALC_00400 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
LCDLCALC_00401 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
LCDLCALC_00402 5.2e-104
LCDLCALC_00405 1.9e-117 cps1D M Domain of unknown function (DUF4422)
LCDLCALC_00406 6.7e-110 rfbP M Bacterial sugar transferase
LCDLCALC_00407 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
LCDLCALC_00408 1.3e-121 ywqD 2.7.10.1 D Capsular exopolysaccharide family
LCDLCALC_00409 6.5e-146 epsB M biosynthesis protein
LCDLCALC_00410 1.9e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LCDLCALC_00412 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LCDLCALC_00413 3.5e-175 S Cysteine-rich secretory protein family
LCDLCALC_00414 1.6e-41
LCDLCALC_00415 2.6e-118 M NlpC/P60 family
LCDLCALC_00416 1.4e-136 M NlpC P60 family protein
LCDLCALC_00417 5e-88 M NlpC/P60 family
LCDLCALC_00418 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
LCDLCALC_00419 3.9e-42
LCDLCALC_00420 2.9e-279 S O-antigen ligase like membrane protein
LCDLCALC_00421 3.3e-112
LCDLCALC_00422 4.7e-221 tnpB L Putative transposase DNA-binding domain
LCDLCALC_00423 5.5e-77 nrdI F NrdI Flavodoxin like
LCDLCALC_00424 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCDLCALC_00425 2.5e-68
LCDLCALC_00426 9.1e-112 yvpB S Peptidase_C39 like family
LCDLCALC_00427 1.1e-83 S Threonine/Serine exporter, ThrE
LCDLCALC_00428 2.4e-136 thrE S Putative threonine/serine exporter
LCDLCALC_00429 8.9e-292 S ABC transporter
LCDLCALC_00430 8.3e-58
LCDLCALC_00431 5e-72 rimL J Acetyltransferase (GNAT) domain
LCDLCALC_00432 1.4e-34
LCDLCALC_00433 1.2e-30
LCDLCALC_00434 1.8e-111 S Protein of unknown function (DUF554)
LCDLCALC_00435 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LCDLCALC_00436 0.0 pepF E oligoendopeptidase F
LCDLCALC_00437 2.9e-31
LCDLCALC_00438 1.3e-69 doc S Prophage maintenance system killer protein
LCDLCALC_00441 4.6e-27 S Enterocin A Immunity
LCDLCALC_00442 1.7e-22 blpT
LCDLCALC_00444 1.6e-25 K Helix-turn-helix XRE-family like proteins
LCDLCALC_00445 1.2e-11
LCDLCALC_00446 2.1e-91 2.1.1.14 E methionine synthase, vitamin-B12 independent
LCDLCALC_00447 1.5e-115 2.1.1.14 E methionine synthase, vitamin-B12 independent
LCDLCALC_00448 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LCDLCALC_00449 2e-264 lctP C L-lactate permease
LCDLCALC_00450 5e-129 znuB U ABC 3 transport family
LCDLCALC_00451 1.6e-117 fhuC P ABC transporter
LCDLCALC_00452 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
LCDLCALC_00453 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
LCDLCALC_00454 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
LCDLCALC_00455 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LCDLCALC_00456 1.8e-136 fruR K DeoR C terminal sensor domain
LCDLCALC_00457 1.8e-218 natB CP ABC-2 family transporter protein
LCDLCALC_00458 1.1e-164 natA S ABC transporter, ATP-binding protein
LCDLCALC_00459 1.7e-67
LCDLCALC_00460 2e-23
LCDLCALC_00461 8.2e-31 yozG K Transcriptional regulator
LCDLCALC_00462 3.7e-83
LCDLCALC_00463 3e-21
LCDLCALC_00467 2.2e-129 blpT
LCDLCALC_00468 1.4e-107 M Transport protein ComB
LCDLCALC_00469 9.3e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LCDLCALC_00470 6.1e-269 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LCDLCALC_00471 1.2e-127 K LytTr DNA-binding domain
LCDLCALC_00472 1.6e-132 2.7.13.3 T GHKL domain
LCDLCALC_00473 1.2e-16
LCDLCALC_00474 2.1e-255 S Archaea bacterial proteins of unknown function
LCDLCALC_00475 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
LCDLCALC_00476 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
LCDLCALC_00477 1e-24
LCDLCALC_00478 9.5e-26
LCDLCALC_00479 2.5e-33
LCDLCALC_00480 1.4e-53 S Enterocin A Immunity
LCDLCALC_00481 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LCDLCALC_00482 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LCDLCALC_00483 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
LCDLCALC_00484 9.6e-121 K response regulator
LCDLCALC_00486 0.0 V ABC transporter
LCDLCALC_00487 4.2e-144 V ABC transporter, ATP-binding protein
LCDLCALC_00488 1.2e-145 V ABC transporter, ATP-binding protein
LCDLCALC_00489 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
LCDLCALC_00490 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LCDLCALC_00491 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
LCDLCALC_00492 8.5e-154 spo0J K Belongs to the ParB family
LCDLCALC_00493 3.4e-138 soj D Sporulation initiation inhibitor
LCDLCALC_00494 1.5e-147 noc K Belongs to the ParB family
LCDLCALC_00495 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
LCDLCALC_00496 3e-53 cvpA S Colicin V production protein
LCDLCALC_00498 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LCDLCALC_00499 6e-151 3.1.3.48 T Tyrosine phosphatase family
LCDLCALC_00500 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
LCDLCALC_00501 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
LCDLCALC_00502 2.4e-110 K WHG domain
LCDLCALC_00503 3e-37
LCDLCALC_00504 1.3e-273 pipD E Dipeptidase
LCDLCALC_00505 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
LCDLCALC_00506 3.3e-176 hrtB V ABC transporter permease
LCDLCALC_00507 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
LCDLCALC_00508 3.5e-111 G phosphoglycerate mutase
LCDLCALC_00509 4.1e-141 aroD S Alpha/beta hydrolase family
LCDLCALC_00510 1.4e-141 S Belongs to the UPF0246 family
LCDLCALC_00511 9e-121
LCDLCALC_00512 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
LCDLCALC_00513 3.9e-186 S Putative peptidoglycan binding domain
LCDLCALC_00514 4e-16
LCDLCALC_00515 2.1e-92 liaI S membrane
LCDLCALC_00516 6.6e-70 XK27_02470 K LytTr DNA-binding domain
LCDLCALC_00517 1.2e-18 S Sugar efflux transporter for intercellular exchange
LCDLCALC_00518 1.3e-250 dtpT U amino acid peptide transporter
LCDLCALC_00519 0.0 pepN 3.4.11.2 E aminopeptidase
LCDLCALC_00520 2.8e-47 lysM M LysM domain
LCDLCALC_00521 1.3e-174
LCDLCALC_00522 1.7e-152 mdtG EGP Major facilitator Superfamily
LCDLCALC_00523 6.9e-47 mdtG EGP Major facilitator Superfamily
LCDLCALC_00524 5.2e-08
LCDLCALC_00525 3e-89 ntd 2.4.2.6 F Nucleoside
LCDLCALC_00526 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LCDLCALC_00527 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
LCDLCALC_00528 2.2e-82 uspA T universal stress protein
LCDLCALC_00530 3.9e-15 phnD P Phosphonate ABC transporter
LCDLCALC_00531 3.1e-133 phnD P Phosphonate ABC transporter
LCDLCALC_00532 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LCDLCALC_00533 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
LCDLCALC_00534 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
LCDLCALC_00535 1.4e-81 L COG3385 FOG Transposase and inactivated derivatives
LCDLCALC_00536 4.6e-88 ymdB S Macro domain protein
LCDLCALC_00537 4.8e-28
LCDLCALC_00540 4.3e-67 K Helix-turn-helix XRE-family like proteins
LCDLCALC_00541 3.3e-147 malG P ABC transporter permease
LCDLCALC_00542 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
LCDLCALC_00543 1.3e-213 malE G Bacterial extracellular solute-binding protein
LCDLCALC_00544 6.8e-209 msmX P Belongs to the ABC transporter superfamily
LCDLCALC_00545 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
LCDLCALC_00546 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
LCDLCALC_00547 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
LCDLCALC_00548 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
LCDLCALC_00549 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
LCDLCALC_00550 4.1e-36 ptp2 3.1.3.48 T Tyrosine phosphatase family
LCDLCALC_00551 4.8e-162 L An automated process has identified a potential problem with this gene model
LCDLCALC_00552 4.1e-101 ptp2 3.1.3.48 T Tyrosine phosphatase family
LCDLCALC_00553 5.1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LCDLCALC_00554 1.5e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LCDLCALC_00555 1.6e-89 G Transmembrane secretion effector
LCDLCALC_00556 2.7e-76 G Transmembrane secretion effector
LCDLCALC_00557 6.1e-136 V ABC transporter transmembrane region
LCDLCALC_00558 2.9e-224 L transposase, IS605 OrfB family
LCDLCALC_00559 1.1e-75 V ABC transporter transmembrane region
LCDLCALC_00560 6.5e-64 L RelB antitoxin
LCDLCALC_00561 2.1e-131 cobQ S glutamine amidotransferase
LCDLCALC_00562 1.8e-81 M NlpC/P60 family
LCDLCALC_00565 2.6e-155
LCDLCALC_00566 1.7e-34
LCDLCALC_00567 2e-32
LCDLCALC_00568 6.2e-163 EG EamA-like transporter family
LCDLCALC_00569 5e-165 EG EamA-like transporter family
LCDLCALC_00570 1.2e-139 yicL EG EamA-like transporter family
LCDLCALC_00571 4.3e-107
LCDLCALC_00572 1.1e-110
LCDLCALC_00573 5.8e-186 XK27_05540 S DUF218 domain
LCDLCALC_00574 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
LCDLCALC_00575 4.7e-85
LCDLCALC_00576 3.9e-57
LCDLCALC_00577 4.7e-25 S Protein conserved in bacteria
LCDLCALC_00578 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
LCDLCALC_00579 7.7e-29 hicA S HicA toxin of bacterial toxin-antitoxin,
LCDLCALC_00580 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LCDLCALC_00581 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LCDLCALC_00582 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LCDLCALC_00583 1.1e-163 L An automated process has identified a potential problem with this gene model
LCDLCALC_00584 1.1e-71 2.5.1.74 H UbiA prenyltransferase family
LCDLCALC_00585 7.7e-26
LCDLCALC_00586 5.7e-84 S PFAM Archaeal ATPase
LCDLCALC_00587 2.2e-85 S PFAM Archaeal ATPase
LCDLCALC_00590 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
LCDLCALC_00591 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
LCDLCALC_00592 1.8e-230 steT_1 E amino acid
LCDLCALC_00593 2.2e-139 puuD S peptidase C26
LCDLCALC_00595 2.4e-172 V HNH endonuclease
LCDLCALC_00596 6.4e-135 S PFAM Archaeal ATPase
LCDLCALC_00597 9.2e-248 yifK E Amino acid permease
LCDLCALC_00598 9.7e-234 cycA E Amino acid permease
LCDLCALC_00599 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LCDLCALC_00600 0.0 clpE O AAA domain (Cdc48 subfamily)
LCDLCALC_00601 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
LCDLCALC_00602 1.1e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LCDLCALC_00603 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
LCDLCALC_00604 0.0 XK27_06780 V ABC transporter permease
LCDLCALC_00605 1.9e-36
LCDLCALC_00606 7.9e-291 ytgP S Polysaccharide biosynthesis protein
LCDLCALC_00607 2.7e-137 lysA2 M Glycosyl hydrolases family 25
LCDLCALC_00608 2.3e-133 S Protein of unknown function (DUF975)
LCDLCALC_00609 7.6e-177 pbpX2 V Beta-lactamase
LCDLCALC_00610 7.3e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LCDLCALC_00611 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LCDLCALC_00612 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
LCDLCALC_00613 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LCDLCALC_00614 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
LCDLCALC_00615 4.1e-44
LCDLCALC_00616 1.5e-206 ywhK S Membrane
LCDLCALC_00617 1.5e-80 ykuL S (CBS) domain
LCDLCALC_00618 0.0 cadA P P-type ATPase
LCDLCALC_00619 2.8e-205 napA P Sodium/hydrogen exchanger family
LCDLCALC_00620 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
LCDLCALC_00621 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
LCDLCALC_00622 4.1e-276 V ABC transporter transmembrane region
LCDLCALC_00623 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
LCDLCALC_00624 5.4e-51
LCDLCALC_00625 4.2e-154 EGP Major facilitator Superfamily
LCDLCALC_00626 3e-111 ropB K Transcriptional regulator
LCDLCALC_00627 2.7e-120 S CAAX protease self-immunity
LCDLCALC_00628 1.6e-194 S DUF218 domain
LCDLCALC_00629 0.0 macB_3 V ABC transporter, ATP-binding protein
LCDLCALC_00630 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LCDLCALC_00631 2.8e-100 S ECF transporter, substrate-specific component
LCDLCALC_00632 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
LCDLCALC_00633 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
LCDLCALC_00634 1.3e-282 xylG 3.6.3.17 S ABC transporter
LCDLCALC_00635 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
LCDLCALC_00636 2.2e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
LCDLCALC_00637 3.7e-159 yeaE S Aldo/keto reductase family
LCDLCALC_00638 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LCDLCALC_00639 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LCDLCALC_00640 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LCDLCALC_00641 9.4e-72
LCDLCALC_00642 8.2e-140 cof S haloacid dehalogenase-like hydrolase
LCDLCALC_00643 8.2e-230 pbuG S permease
LCDLCALC_00644 2.1e-76 S ABC-2 family transporter protein
LCDLCALC_00645 4.7e-60 S ABC-2 family transporter protein
LCDLCALC_00646 2.4e-92 V ABC transporter, ATP-binding protein
LCDLCALC_00647 2.3e-36 K helix_turn_helix, mercury resistance
LCDLCALC_00648 7.5e-231 pbuG S permease
LCDLCALC_00649 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
LCDLCALC_00650 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
LCDLCALC_00651 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
LCDLCALC_00653 1.9e-83 K Transcriptional regulator
LCDLCALC_00654 6.1e-61 K Transcriptional regulator
LCDLCALC_00655 2e-225 S cog cog1373
LCDLCALC_00656 9.7e-146 S haloacid dehalogenase-like hydrolase
LCDLCALC_00657 2.5e-226 pbuG S permease
LCDLCALC_00658 1.4e-37 S Putative adhesin
LCDLCALC_00659 2.6e-151 V ABC transporter transmembrane region
LCDLCALC_00660 4.6e-138
LCDLCALC_00661 1.8e-31
LCDLCALC_00664 2.4e-36
LCDLCALC_00665 9.2e-57 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LCDLCALC_00666 1.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LCDLCALC_00667 0.0 copA 3.6.3.54 P P-type ATPase
LCDLCALC_00668 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
LCDLCALC_00669 1.2e-105
LCDLCALC_00670 7e-248 EGP Sugar (and other) transporter
LCDLCALC_00671 1.2e-18
LCDLCALC_00672 2.8e-210
LCDLCALC_00673 3.5e-136 S SLAP domain
LCDLCALC_00674 1.3e-117 S SLAP domain
LCDLCALC_00675 1.1e-106 S Bacteriocin helveticin-J
LCDLCALC_00676 1.2e-44
LCDLCALC_00677 1.1e-57 ps115 K Helix-turn-helix XRE-family like proteins
LCDLCALC_00678 4e-32 E Zn peptidase
LCDLCALC_00679 3.9e-287 clcA P chloride
LCDLCALC_00680 1.7e-174 L COG3385 FOG Transposase and inactivated derivatives
LCDLCALC_00681 1.6e-105 tag 3.2.2.20 L glycosylase
LCDLCALC_00682 3.9e-84
LCDLCALC_00683 1.7e-273 S Calcineurin-like phosphoesterase
LCDLCALC_00684 0.0 asnB 6.3.5.4 E Asparagine synthase
LCDLCALC_00685 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
LCDLCALC_00686 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
LCDLCALC_00687 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCDLCALC_00688 2.1e-103 S Iron-sulfur cluster assembly protein
LCDLCALC_00689 1.5e-230 XK27_04775 S PAS domain
LCDLCALC_00690 1e-210 yttB EGP Major facilitator Superfamily
LCDLCALC_00691 7.7e-10 C Flavodoxin
LCDLCALC_00692 3.2e-79 S X-Pro dipeptidyl-peptidase (S15 family)
LCDLCALC_00693 4.3e-45 K Tetracycline repressor, C-terminal all-alpha domain
LCDLCALC_00695 6.6e-90 K LysR substrate binding domain
LCDLCALC_00696 8.9e-34 S Domain of unknown function (DUF4440)
LCDLCALC_00697 9.8e-69 GM NAD(P)H-binding
LCDLCALC_00698 7e-135 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
LCDLCALC_00699 7.9e-49 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LCDLCALC_00700 7.4e-42 C 2Fe-2S iron-sulfur cluster binding domain
LCDLCALC_00701 2.8e-140 sufC O FeS assembly ATPase SufC
LCDLCALC_00702 3.5e-174 sufD O FeS assembly protein SufD
LCDLCALC_00703 5.3e-178 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LCDLCALC_00704 2.4e-59 nifU C SUF system FeS assembly protein, NifU family
LCDLCALC_00705 2e-266 sufB O assembly protein SufB
LCDLCALC_00706 2.4e-45 yitW S Iron-sulfur cluster assembly protein
LCDLCALC_00707 2.9e-247 mntH P H( )-stimulated, divalent metal cation uptake system
LCDLCALC_00708 1.9e-41
LCDLCALC_00709 1.4e-134 D Ftsk spoiiie family protein
LCDLCALC_00710 5.1e-145 S Replication initiation factor
LCDLCALC_00711 3.9e-55
LCDLCALC_00712 2.3e-26
LCDLCALC_00713 9.5e-220 L Belongs to the 'phage' integrase family
LCDLCALC_00715 2.5e-62 yfiL V ABC transporter
LCDLCALC_00716 2.9e-46 V Transport permease protein
LCDLCALC_00717 3.4e-09
LCDLCALC_00718 1.1e-68 sagB C Nitroreductase family
LCDLCALC_00719 5.1e-56
LCDLCALC_00720 1.8e-131 sagD S YcaO cyclodehydratase, ATP-ad Mg2+-binding
LCDLCALC_00722 7.6e-25 S SLAP domain
LCDLCALC_00723 4.3e-24 S SLAP domain
LCDLCALC_00724 3.7e-102 L Integrase
LCDLCALC_00725 3.6e-69 T Toxin-antitoxin system, toxin component, MazF family
LCDLCALC_00726 1.3e-30
LCDLCALC_00727 1.5e-189 L Transposase and inactivated derivatives, IS30 family
LCDLCALC_00728 8.2e-85 scrR K Periplasmic binding protein domain
LCDLCALC_00729 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LCDLCALC_00730 0.0 fhaB M Rib/alpha-like repeat
LCDLCALC_00731 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
LCDLCALC_00732 2.9e-143 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
LCDLCALC_00734 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
LCDLCALC_00735 7.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
LCDLCALC_00736 1.4e-127 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
LCDLCALC_00737 1.7e-42 M Glycosyl transferase family 2
LCDLCALC_00738 5.3e-76 M Glycosyltransferase, group 1 family protein
LCDLCALC_00739 5.1e-82 glfT1 1.1.1.133 S Glycosyltransferase, group 2 family protein
LCDLCALC_00740 2.1e-45 S O-antigen ligase like membrane protein
LCDLCALC_00741 1.6e-31 2.7.7.65 T GGDEF domain
LCDLCALC_00742 8.2e-36
LCDLCALC_00743 5.2e-112 ica2 GT2 M Glycosyl transferase family group 2
LCDLCALC_00744 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
LCDLCALC_00745 2.4e-34 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
LCDLCALC_00746 2.2e-22
LCDLCALC_00747 3.3e-140 repB EP Plasmid replication protein
LCDLCALC_00748 1e-78 S helix_turn_helix, Deoxyribose operon repressor
LCDLCALC_00749 0.0 pepO 3.4.24.71 O Peptidase family M13
LCDLCALC_00750 8.5e-279 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LCDLCALC_00751 4e-60 L Resolvase, N terminal domain
LCDLCALC_00752 8.7e-26 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LCDLCALC_00753 2.3e-101 L An automated process has identified a potential problem with this gene model
LCDLCALC_00756 4.1e-153 L Belongs to the 'phage' integrase family
LCDLCALC_00759 1.3e-149 oppA E ABC transporter substrate-binding protein
LCDLCALC_00760 2.2e-54 oppA E ABC transporter substrate-binding protein
LCDLCALC_00761 1.4e-173 L Psort location Cytoplasmic, score
LCDLCALC_00762 5.8e-100 L Helix-turn-helix domain
LCDLCALC_00763 1.3e-160 L hmm pf00665
LCDLCALC_00764 3.3e-127 L PFAM transposase IS116 IS110 IS902
LCDLCALC_00765 8.7e-10 K FCD
LCDLCALC_00766 4.7e-26 K FCD
LCDLCALC_00767 1.6e-60 clcA P chloride
LCDLCALC_00768 8.8e-41 clcA P chloride
LCDLCALC_00769 0.0 kup P Transport of potassium into the cell
LCDLCALC_00770 7.3e-74
LCDLCALC_00771 2.1e-45 S PFAM Archaeal ATPase
LCDLCALC_00773 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
LCDLCALC_00774 5.9e-45
LCDLCALC_00775 3e-270 L Transposase DDE domain
LCDLCALC_00776 1.5e-234 L Transposase DDE domain
LCDLCALC_00777 1.5e-180 S Domain of unknown function (DUF389)
LCDLCALC_00778 1.8e-79
LCDLCALC_00779 7.4e-49 S Peptidase propeptide and YPEB domain
LCDLCALC_00780 4.1e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
LCDLCALC_00781 3.3e-37
LCDLCALC_00782 2.4e-47 K helix_turn_helix, mercury resistance
LCDLCALC_00783 3e-112 L PFAM transposase IS116 IS110 IS902
LCDLCALC_00784 2.3e-184 S Uncharacterised protein family (UPF0236)
LCDLCALC_00785 1.2e-10
LCDLCALC_00786 1.2e-49 S Protein of unknown function (DUF3021)
LCDLCALC_00787 2.8e-65 K LytTr DNA-binding domain
LCDLCALC_00789 5.3e-41
LCDLCALC_00790 1.2e-77 K DNA-templated transcription, initiation
LCDLCALC_00792 1.2e-18
LCDLCALC_00793 4.3e-145 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LCDLCALC_00795 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LCDLCALC_00796 2.2e-105 S SLAP domain
LCDLCALC_00797 4.3e-40 S Protein of unknown function (DUF2922)
LCDLCALC_00798 5.5e-30
LCDLCALC_00800 1.2e-47 L Transposase, IS116 IS110 IS902 family
LCDLCALC_00801 3.3e-158 L DDE superfamily endonuclease
LCDLCALC_00802 1.2e-132 S SLAP domain
LCDLCALC_00804 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LCDLCALC_00805 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
LCDLCALC_00806 8.8e-177 yjbQ P TrkA C-terminal domain protein
LCDLCALC_00807 1.9e-113 yjbQ P TrkA C-terminal domain protein
LCDLCALC_00808 9.7e-107 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LCDLCALC_00809 7.8e-161 S Oxidoreductase family, NAD-binding Rossmann fold
LCDLCALC_00810 1.7e-129
LCDLCALC_00811 2.1e-116
LCDLCALC_00812 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LCDLCALC_00813 1.4e-98 G Aldose 1-epimerase
LCDLCALC_00814 2.3e-201 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LCDLCALC_00815 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LCDLCALC_00816 0.0 XK27_08315 M Sulfatase
LCDLCALC_00817 8.4e-265 S Fibronectin type III domain
LCDLCALC_00818 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LCDLCALC_00819 3.4e-53
LCDLCALC_00821 4.6e-257 pepC 3.4.22.40 E aminopeptidase
LCDLCALC_00822 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LCDLCALC_00823 5e-301 oppA E ABC transporter, substratebinding protein
LCDLCALC_00824 1.6e-310 oppA E ABC transporter, substratebinding protein
LCDLCALC_00825 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LCDLCALC_00826 5.7e-69 rplI J Binds to the 23S rRNA
LCDLCALC_00827 1.9e-253 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LCDLCALC_00828 3.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LCDLCALC_00829 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCDLCALC_00830 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCDLCALC_00831 2.7e-199 oppD P Belongs to the ABC transporter superfamily
LCDLCALC_00832 1.9e-175 oppF P Belongs to the ABC transporter superfamily
LCDLCALC_00833 5.2e-256 pepC 3.4.22.40 E aminopeptidase
LCDLCALC_00834 3.9e-72 hsp O Belongs to the small heat shock protein (HSP20) family
LCDLCALC_00835 1.3e-28 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LCDLCALC_00836 6e-112
LCDLCALC_00838 1.7e-110 E Belongs to the SOS response-associated peptidase family
LCDLCALC_00839 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
LCDLCALC_00840 4e-89 comEB 3.5.4.12 F MafB19-like deaminase
LCDLCALC_00841 2e-103 S TPM domain
LCDLCALC_00842 2.4e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
LCDLCALC_00843 2.5e-311 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
LCDLCALC_00844 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCDLCALC_00845 1e-147 tatD L hydrolase, TatD family
LCDLCALC_00846 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LCDLCALC_00847 6.7e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LCDLCALC_00848 4.5e-39 veg S Biofilm formation stimulator VEG
LCDLCALC_00849 1.5e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LCDLCALC_00850 2.6e-173 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LCDLCALC_00851 5.3e-80
LCDLCALC_00852 7.8e-292 S SLAP domain
LCDLCALC_00853 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCDLCALC_00854 4.2e-172 2.7.1.2 GK ROK family
LCDLCALC_00855 5.6e-43
LCDLCALC_00856 3.6e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
LCDLCALC_00857 6.9e-69 S Domain of unknown function (DUF1934)
LCDLCALC_00858 1.5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LCDLCALC_00859 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LCDLCALC_00860 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LCDLCALC_00861 1.8e-74 K acetyltransferase
LCDLCALC_00862 5.7e-285 pipD E Dipeptidase
LCDLCALC_00863 3.7e-156 msmR K AraC-like ligand binding domain
LCDLCALC_00864 1.5e-223 pbuX F xanthine permease
LCDLCALC_00865 9e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LCDLCALC_00866 2.4e-43 K Helix-turn-helix
LCDLCALC_00867 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LCDLCALC_00869 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LCDLCALC_00870 3.6e-225 3.2.1.18 GH33 M Rib/alpha-like repeat
LCDLCALC_00871 1.3e-141 yfeO P Voltage gated chloride channel
LCDLCALC_00872 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
LCDLCALC_00873 1.4e-51
LCDLCALC_00874 2.1e-42
LCDLCALC_00875 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LCDLCALC_00876 9.5e-297 ybeC E amino acid
LCDLCALC_00877 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
LCDLCALC_00878 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
LCDLCALC_00879 2.5e-39 rpmE2 J Ribosomal protein L31
LCDLCALC_00880 1.2e-258 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LCDLCALC_00881 4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LCDLCALC_00882 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LCDLCALC_00883 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LCDLCALC_00884 3.4e-129 S (CBS) domain
LCDLCALC_00885 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LCDLCALC_00886 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LCDLCALC_00887 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LCDLCALC_00888 1.6e-33 yabO J S4 domain protein
LCDLCALC_00889 6.8e-60 divIC D Septum formation initiator
LCDLCALC_00890 1.8e-62 yabR J S1 RNA binding domain
LCDLCALC_00891 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LCDLCALC_00892 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LCDLCALC_00893 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LCDLCALC_00894 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LCDLCALC_00895 1.1e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LCDLCALC_00896 1.4e-83 K FR47-like protein
LCDLCALC_00897 1.6e-08
LCDLCALC_00898 1.6e-08
LCDLCALC_00899 1.6e-08
LCDLCALC_00901 3.5e-70 yebR 1.8.4.14 T GAF domain-containing protein
LCDLCALC_00902 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LCDLCALC_00903 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCDLCALC_00904 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCDLCALC_00905 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
LCDLCALC_00906 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LCDLCALC_00907 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LCDLCALC_00908 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LCDLCALC_00909 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LCDLCALC_00910 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LCDLCALC_00911 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
LCDLCALC_00912 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LCDLCALC_00913 3.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LCDLCALC_00914 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LCDLCALC_00915 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LCDLCALC_00916 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LCDLCALC_00917 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LCDLCALC_00918 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
LCDLCALC_00919 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LCDLCALC_00920 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LCDLCALC_00921 2.2e-32 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LCDLCALC_00922 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LCDLCALC_00923 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LCDLCALC_00924 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LCDLCALC_00925 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LCDLCALC_00926 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LCDLCALC_00927 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LCDLCALC_00928 2.3e-24 rpmD J Ribosomal protein L30
LCDLCALC_00929 1.3e-70 rplO J Binds to the 23S rRNA
LCDLCALC_00930 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LCDLCALC_00931 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LCDLCALC_00932 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LCDLCALC_00933 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LCDLCALC_00934 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LCDLCALC_00935 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LCDLCALC_00936 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCDLCALC_00937 1.4e-60 rplQ J Ribosomal protein L17
LCDLCALC_00938 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LCDLCALC_00939 1.3e-156 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LCDLCALC_00940 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LCDLCALC_00941 4.8e-148 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LCDLCALC_00942 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LCDLCALC_00943 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
LCDLCALC_00944 3.6e-183 L Phage integrase family
LCDLCALC_00945 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
LCDLCALC_00946 3.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LCDLCALC_00947 6e-132 S membrane transporter protein
LCDLCALC_00948 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
LCDLCALC_00949 7.3e-161 czcD P cation diffusion facilitator family transporter
LCDLCALC_00950 1.4e-23
LCDLCALC_00951 2.6e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LCDLCALC_00952 5.4e-183 S AAA domain
LCDLCALC_00953 7.3e-44
LCDLCALC_00954 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
LCDLCALC_00955 4.1e-52
LCDLCALC_00956 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
LCDLCALC_00957 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LCDLCALC_00958 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LCDLCALC_00959 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LCDLCALC_00960 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LCDLCALC_00961 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCDLCALC_00962 1.2e-94 sigH K Belongs to the sigma-70 factor family
LCDLCALC_00963 1.7e-34
LCDLCALC_00964 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
LCDLCALC_00965 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LCDLCALC_00966 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LCDLCALC_00967 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
LCDLCALC_00968 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LCDLCALC_00969 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LCDLCALC_00970 2.8e-157 pstS P Phosphate
LCDLCALC_00971 8e-150 pstC P probably responsible for the translocation of the substrate across the membrane
LCDLCALC_00972 6.5e-154 pstA P Phosphate transport system permease protein PstA
LCDLCALC_00973 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LCDLCALC_00974 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LCDLCALC_00975 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
LCDLCALC_00976 2.8e-90 L An automated process has identified a potential problem with this gene model
LCDLCALC_00977 1.5e-11 GT2,GT4 M family 8
LCDLCALC_00978 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LCDLCALC_00979 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LCDLCALC_00980 8.7e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
LCDLCALC_00981 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
LCDLCALC_00982 9e-26
LCDLCALC_00983 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LCDLCALC_00984 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LCDLCALC_00985 5.7e-106 2.4.1.58 GT8 M family 8
LCDLCALC_00986 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
LCDLCALC_00987 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LCDLCALC_00988 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LCDLCALC_00989 1.1e-34 S Protein of unknown function (DUF2508)
LCDLCALC_00990 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LCDLCALC_00991 8.9e-53 yaaQ S Cyclic-di-AMP receptor
LCDLCALC_00992 1.5e-155 holB 2.7.7.7 L DNA polymerase III
LCDLCALC_00993 1.8e-59 yabA L Involved in initiation control of chromosome replication
LCDLCALC_00994 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LCDLCALC_00995 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
LCDLCALC_00996 2.2e-85 S ECF transporter, substrate-specific component
LCDLCALC_00997 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
LCDLCALC_00998 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
LCDLCALC_00999 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LCDLCALC_01000 1.9e-245 L Transposase IS66 family
LCDLCALC_01001 8.7e-34 S Transposase C of IS166 homeodomain
LCDLCALC_01002 9.3e-64 L PFAM IS66 Orf2 family protein
LCDLCALC_01003 7.7e-22
LCDLCALC_01004 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
LCDLCALC_01005 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
LCDLCALC_01006 3.4e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
LCDLCALC_01007 0.0 uup S ABC transporter, ATP-binding protein
LCDLCALC_01008 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LCDLCALC_01009 3.3e-164 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
LCDLCALC_01010 5.2e-170 degV S DegV family
LCDLCALC_01011 1.1e-135 V ABC transporter transmembrane region
LCDLCALC_01012 1.8e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
LCDLCALC_01014 1.4e-16
LCDLCALC_01015 4.4e-192 L COG2963 Transposase and inactivated derivatives
LCDLCALC_01016 1.1e-183 scrR K helix_turn _helix lactose operon repressor
LCDLCALC_01017 3.7e-295 scrB 3.2.1.26 GH32 G invertase
LCDLCALC_01018 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
LCDLCALC_01019 2.3e-181 M CHAP domain
LCDLCALC_01020 3.5e-75
LCDLCALC_01021 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LCDLCALC_01022 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LCDLCALC_01023 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LCDLCALC_01024 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LCDLCALC_01025 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LCDLCALC_01026 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LCDLCALC_01027 9.6e-41 yajC U Preprotein translocase
LCDLCALC_01028 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LCDLCALC_01029 6.2e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCDLCALC_01030 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
LCDLCALC_01031 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LCDLCALC_01032 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LCDLCALC_01033 2e-42 yrzL S Belongs to the UPF0297 family
LCDLCALC_01034 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LCDLCALC_01035 1.1e-50 yrzB S Belongs to the UPF0473 family
LCDLCALC_01036 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LCDLCALC_01037 3.5e-54 trxA O Belongs to the thioredoxin family
LCDLCALC_01038 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LCDLCALC_01039 1.1e-71 yslB S Protein of unknown function (DUF2507)
LCDLCALC_01040 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LCDLCALC_01041 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LCDLCALC_01042 7.7e-30 ropB K Helix-turn-helix domain
LCDLCALC_01043 5.4e-113
LCDLCALC_01044 1.7e-139
LCDLCALC_01045 6.9e-100 V ATPases associated with a variety of cellular activities
LCDLCALC_01046 3.7e-146 ykuT M mechanosensitive ion channel
LCDLCALC_01047 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LCDLCALC_01048 1.3e-36
LCDLCALC_01049 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LCDLCALC_01050 3.2e-181 ccpA K catabolite control protein A
LCDLCALC_01051 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LCDLCALC_01052 4.3e-55
LCDLCALC_01053 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LCDLCALC_01054 2.1e-92 yutD S Protein of unknown function (DUF1027)
LCDLCALC_01055 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LCDLCALC_01056 3.7e-100 S Protein of unknown function (DUF1461)
LCDLCALC_01057 6.8e-116 dedA S SNARE-like domain protein
LCDLCALC_01058 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
LCDLCALC_01086 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
LCDLCALC_01087 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
LCDLCALC_01088 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LCDLCALC_01089 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LCDLCALC_01090 1.7e-29 secG U Preprotein translocase
LCDLCALC_01091 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LCDLCALC_01092 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LCDLCALC_01094 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
LCDLCALC_01095 1.7e-129 manY G PTS system
LCDLCALC_01096 1e-173 manN G system, mannose fructose sorbose family IID component
LCDLCALC_01097 1.1e-62 manO S Domain of unknown function (DUF956)
LCDLCALC_01098 3.3e-158 K Transcriptional regulator
LCDLCALC_01099 1.3e-85 maa S transferase hexapeptide repeat
LCDLCALC_01100 1.3e-241 cycA E Amino acid permease
LCDLCALC_01101 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LCDLCALC_01102 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LCDLCALC_01103 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LCDLCALC_01104 0.0 mtlR K Mga helix-turn-helix domain
LCDLCALC_01105 5.8e-170 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
LCDLCALC_01106 2.1e-123 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
LCDLCALC_01107 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LCDLCALC_01108 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
LCDLCALC_01109 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
LCDLCALC_01110 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
LCDLCALC_01111 2.1e-32
LCDLCALC_01112 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
LCDLCALC_01113 2.3e-156 K Helix-turn-helix XRE-family like proteins
LCDLCALC_01114 3.9e-298 V ABC transporter transmembrane region
LCDLCALC_01115 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
LCDLCALC_01116 1.7e-193 S TerB-C domain
LCDLCALC_01117 2.6e-138 S TerB-C domain
LCDLCALC_01118 1.4e-245 P P-loop Domain of unknown function (DUF2791)
LCDLCALC_01119 0.0 lhr L DEAD DEAH box helicase
LCDLCALC_01120 1.4e-60
LCDLCALC_01121 4.3e-228 amtB P ammonium transporter
LCDLCALC_01122 1.9e-121 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
LCDLCALC_01124 6.6e-61 psiE S Phosphate-starvation-inducible E
LCDLCALC_01125 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
LCDLCALC_01126 2.9e-69 S Iron-sulphur cluster biosynthesis
LCDLCALC_01128 2.3e-30
LCDLCALC_01129 2.6e-171 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
LCDLCALC_01130 6.2e-12
LCDLCALC_01131 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LCDLCALC_01132 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LCDLCALC_01133 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LCDLCALC_01134 5.8e-78 M LysM domain protein
LCDLCALC_01135 5.4e-60 L Resolvase, N-terminal
LCDLCALC_01136 1.6e-166 L Putative transposase DNA-binding domain
LCDLCALC_01137 1e-190 L Transposase and inactivated derivatives, IS30 family
LCDLCALC_01141 1.9e-19 L Replication initiation factor
LCDLCALC_01142 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCDLCALC_01143 9.3e-74 nrdI F NrdI Flavodoxin like
LCDLCALC_01144 3.6e-193 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCDLCALC_01145 1.1e-109 tnpR1 L Resolvase, N terminal domain
LCDLCALC_01146 4.7e-70 L IS1381, transposase OrfA
LCDLCALC_01147 1.1e-76 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LCDLCALC_01148 1.3e-28
LCDLCALC_01149 1.7e-142 soj D AAA domain
LCDLCALC_01150 3.8e-167 repA S Replication initiator protein A
LCDLCALC_01151 8.5e-128 S Fic/DOC family
LCDLCALC_01152 6.8e-226 I Protein of unknown function (DUF2974)
LCDLCALC_01153 1.9e-116 yhiD S MgtC family
LCDLCALC_01155 1.4e-18 K Helix-turn-helix XRE-family like proteins
LCDLCALC_01156 6.9e-64
LCDLCALC_01157 1.4e-17
LCDLCALC_01158 4.7e-159 D nuclear chromosome segregation
LCDLCALC_01159 1.2e-105 G Phosphoglycerate mutase family
LCDLCALC_01160 2.6e-89 G Histidine phosphatase superfamily (branch 1)
LCDLCALC_01161 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
LCDLCALC_01162 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LCDLCALC_01164 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
LCDLCALC_01166 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
LCDLCALC_01167 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
LCDLCALC_01168 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
LCDLCALC_01169 4.4e-144 K SIS domain
LCDLCALC_01170 1.8e-43 slpX S SLAP domain
LCDLCALC_01171 5.3e-167 slpX S SLAP domain
LCDLCALC_01172 1.3e-22 3.6.4.12 S transposase or invertase
LCDLCALC_01173 6.6e-11
LCDLCALC_01174 3.2e-240 npr 1.11.1.1 C NADH oxidase
LCDLCALC_01177 4.4e-239 oppA2 E ABC transporter, substratebinding protein
LCDLCALC_01178 3.4e-45 oppA2 E ABC transporter, substratebinding protein
LCDLCALC_01179 3.3e-179
LCDLCALC_01180 4.6e-123 gntR1 K UTRA
LCDLCALC_01181 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
LCDLCALC_01182 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LCDLCALC_01183 1.7e-204 csaB M Glycosyl transferases group 1
LCDLCALC_01184 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LCDLCALC_01185 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LCDLCALC_01186 1.4e-204 tnpB L Putative transposase DNA-binding domain
LCDLCALC_01187 0.0 pacL 3.6.3.8 P P-type ATPase
LCDLCALC_01188 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LCDLCALC_01189 6e-258 epsU S Polysaccharide biosynthesis protein
LCDLCALC_01190 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
LCDLCALC_01191 4.1e-83 ydcK S Belongs to the SprT family
LCDLCALC_01193 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
LCDLCALC_01194 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LCDLCALC_01195 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LCDLCALC_01196 5.8e-203 camS S sex pheromone
LCDLCALC_01197 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LCDLCALC_01198 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LCDLCALC_01199 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LCDLCALC_01200 2.7e-171 yegS 2.7.1.107 G Lipid kinase
LCDLCALC_01201 4.3e-108 ybhL S Belongs to the BI1 family
LCDLCALC_01202 2.6e-57
LCDLCALC_01203 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
LCDLCALC_01204 2.8e-244 nhaC C Na H antiporter NhaC
LCDLCALC_01205 6.3e-201 pbpX V Beta-lactamase
LCDLCALC_01206 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCDLCALC_01207 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
LCDLCALC_01212 1.9e-259 emrY EGP Major facilitator Superfamily
LCDLCALC_01213 2e-91 yxdD K Bacterial regulatory proteins, tetR family
LCDLCALC_01214 0.0 4.2.1.53 S Myosin-crossreactive antigen
LCDLCALC_01215 5.5e-148 S cog cog1373
LCDLCALC_01216 1.9e-22 K Putative DNA-binding domain
LCDLCALC_01217 7.6e-239 pyrP F Permease
LCDLCALC_01218 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LCDLCALC_01219 9.2e-262 emrY EGP Major facilitator Superfamily
LCDLCALC_01220 5.1e-155 mdtG EGP Major facilitator Superfamily
LCDLCALC_01221 4.7e-182 pepA E M42 glutamyl aminopeptidase
LCDLCALC_01222 2.2e-311 ybiT S ABC transporter, ATP-binding protein
LCDLCALC_01223 5.9e-174 S Aldo keto reductase
LCDLCALC_01224 2.7e-138
LCDLCALC_01225 2.8e-202 steT E amino acid
LCDLCALC_01226 2.4e-26 steT E amino acid
LCDLCALC_01227 8.6e-243 steT E amino acid
LCDLCALC_01228 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
LCDLCALC_01229 1.9e-147 glnH ET ABC transporter
LCDLCALC_01230 1.4e-80 K Transcriptional regulator, MarR family
LCDLCALC_01231 4.5e-308 XK27_09600 V ABC transporter, ATP-binding protein
LCDLCALC_01232 3.1e-173 V ABC transporter transmembrane region
LCDLCALC_01233 4.3e-138 V ABC transporter transmembrane region
LCDLCALC_01234 1.6e-100 S ABC-type cobalt transport system, permease component
LCDLCALC_01235 1e-246 G MFS/sugar transport protein
LCDLCALC_01236 9.8e-39 udk 2.7.1.48 F Zeta toxin
LCDLCALC_01237 3.8e-46 udk 2.7.1.48 F Zeta toxin
LCDLCALC_01238 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LCDLCALC_01239 1.2e-146 glnH ET ABC transporter substrate-binding protein
LCDLCALC_01240 3.7e-90 gluC P ABC transporter permease
LCDLCALC_01241 4.7e-109 glnP P ABC transporter permease
LCDLCALC_01242 1.1e-164 S Protein of unknown function (DUF2974)
LCDLCALC_01243 5.6e-86
LCDLCALC_01244 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
LCDLCALC_01245 1.3e-235 G Bacterial extracellular solute-binding protein
LCDLCALC_01246 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
LCDLCALC_01247 3.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCDLCALC_01248 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LCDLCALC_01249 0.0 kup P Transport of potassium into the cell
LCDLCALC_01250 9.1e-175 rihB 3.2.2.1 F Nucleoside
LCDLCALC_01251 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
LCDLCALC_01252 1.2e-154 S hydrolase
LCDLCALC_01253 2.5e-59 S Enterocin A Immunity
LCDLCALC_01254 3.1e-136 glcR K DeoR C terminal sensor domain
LCDLCALC_01255 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
LCDLCALC_01256 2e-160 rssA S Phospholipase, patatin family
LCDLCALC_01257 5.4e-147 S hydrolase
LCDLCALC_01258 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
LCDLCALC_01259 9.2e-147 glvR K Helix-turn-helix domain, rpiR family
LCDLCALC_01260 1.6e-80
LCDLCALC_01261 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LCDLCALC_01262 2.1e-39
LCDLCALC_01263 3.9e-119 C nitroreductase
LCDLCALC_01264 1.7e-249 yhdP S Transporter associated domain
LCDLCALC_01265 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LCDLCALC_01266 0.0 1.3.5.4 C FAD binding domain
LCDLCALC_01267 4.2e-87 L PFAM transposase, IS4 family protein
LCDLCALC_01268 1.2e-49 L PFAM transposase, IS4 family protein
LCDLCALC_01269 1.7e-213 1.3.5.4 C FAD binding domain
LCDLCALC_01270 3.4e-126 1.3.5.4 C FAD binding domain
LCDLCALC_01271 8.2e-230 potE E amino acid
LCDLCALC_01272 2.6e-61 M Glycosyl hydrolases family 25
LCDLCALC_01273 1.3e-61 M Glycosyl hydrolases family 25
LCDLCALC_01274 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
LCDLCALC_01275 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LCDLCALC_01277 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LCDLCALC_01278 7e-87 gtcA S Teichoic acid glycosylation protein
LCDLCALC_01279 4.1e-80 fld C Flavodoxin
LCDLCALC_01280 8.8e-29
LCDLCALC_01283 4.9e-111 K Helix-turn-helix XRE-family like proteins
LCDLCALC_01284 2.5e-75 K Helix-turn-helix domain
LCDLCALC_01285 1.5e-25 S CAAX protease self-immunity
LCDLCALC_01286 1.4e-22 S CAAX protease self-immunity
LCDLCALC_01287 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
LCDLCALC_01289 1.6e-96 ybaT E Amino acid permease
LCDLCALC_01290 1.7e-07 S LPXTG cell wall anchor motif
LCDLCALC_01291 4.4e-146 S Putative ABC-transporter type IV
LCDLCALC_01293 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LCDLCALC_01294 1.8e-235 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LCDLCALC_01295 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LCDLCALC_01296 1.2e-232 oppA E ABC transporter substrate-binding protein
LCDLCALC_01297 2.1e-95 oppA E ABC transporter substrate-binding protein
LCDLCALC_01298 3.2e-176 K AI-2E family transporter
LCDLCALC_01299 2.2e-102 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
LCDLCALC_01300 4.1e-18
LCDLCALC_01301 4.1e-245 G Major Facilitator
LCDLCALC_01302 1.3e-79 E Zn peptidase
LCDLCALC_01303 1e-41 ps115 K Helix-turn-helix XRE-family like proteins
LCDLCALC_01304 5.6e-45
LCDLCALC_01305 4.5e-66 S Bacteriocin helveticin-J
LCDLCALC_01306 1.7e-66 S SLAP domain
LCDLCALC_01307 5.8e-45
LCDLCALC_01308 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
LCDLCALC_01309 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
LCDLCALC_01310 1.7e-174 ABC-SBP S ABC transporter
LCDLCALC_01311 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LCDLCALC_01312 1.6e-48 P CorA-like Mg2+ transporter protein
LCDLCALC_01313 5.2e-75 P CorA-like Mg2+ transporter protein
LCDLCALC_01314 3.5e-160 yvgN C Aldo keto reductase
LCDLCALC_01315 0.0 tetP J elongation factor G
LCDLCALC_01316 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
LCDLCALC_01317 1.2e-134 EGP Major facilitator Superfamily
LCDLCALC_01319 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
LCDLCALC_01320 3.6e-163 yihY S Belongs to the UPF0761 family
LCDLCALC_01321 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LCDLCALC_01322 5.6e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
LCDLCALC_01323 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
LCDLCALC_01324 9.4e-46
LCDLCALC_01325 1.8e-38 D Alpha beta
LCDLCALC_01326 1.4e-118 D Alpha beta
LCDLCALC_01327 3e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCDLCALC_01328 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
LCDLCALC_01329 1.6e-85
LCDLCALC_01330 2.7e-74
LCDLCALC_01331 1.4e-140 hlyX S Transporter associated domain
LCDLCALC_01332 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LCDLCALC_01333 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
LCDLCALC_01334 0.0 clpE O Belongs to the ClpA ClpB family
LCDLCALC_01335 8.1e-175 ulaG S Beta-lactamase superfamily domain
LCDLCALC_01336 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LCDLCALC_01337 1.3e-231 ulaA S PTS system sugar-specific permease component
LCDLCALC_01338 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
LCDLCALC_01339 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
LCDLCALC_01340 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
LCDLCALC_01341 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
LCDLCALC_01342 5.2e-68 L haloacid dehalogenase-like hydrolase
LCDLCALC_01343 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
LCDLCALC_01344 1.4e-16 L Transposase
LCDLCALC_01345 1.9e-12 L Transposase
LCDLCALC_01346 5.9e-13 K Acetyltransferase (GNAT) domain
LCDLCALC_01347 5.3e-26
LCDLCALC_01348 8.5e-41 ptsH G phosphocarrier protein HPR
LCDLCALC_01349 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LCDLCALC_01350 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LCDLCALC_01351 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LCDLCALC_01352 1.4e-158 coiA 3.6.4.12 S Competence protein
LCDLCALC_01353 4.6e-114 yjbH Q Thioredoxin
LCDLCALC_01354 6.8e-110 yjbK S CYTH
LCDLCALC_01355 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
LCDLCALC_01356 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LCDLCALC_01357 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LCDLCALC_01358 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
LCDLCALC_01359 4.2e-92 S SNARE associated Golgi protein
LCDLCALC_01360 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
LCDLCALC_01361 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
LCDLCALC_01362 2.6e-214 yubA S AI-2E family transporter
LCDLCALC_01363 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LCDLCALC_01364 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
LCDLCALC_01365 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LCDLCALC_01366 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
LCDLCALC_01367 1.9e-236 S Peptidase M16
LCDLCALC_01368 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
LCDLCALC_01369 5.2e-97 ymfM S Helix-turn-helix domain
LCDLCALC_01370 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LCDLCALC_01371 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LCDLCALC_01372 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
LCDLCALC_01373 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
LCDLCALC_01374 5.1e-119 yvyE 3.4.13.9 S YigZ family
LCDLCALC_01375 4.7e-246 comFA L Helicase C-terminal domain protein
LCDLCALC_01376 9.4e-132 comFC S Competence protein
LCDLCALC_01377 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LCDLCALC_01378 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LCDLCALC_01379 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LCDLCALC_01380 5.1e-17
LCDLCALC_01381 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LCDLCALC_01382 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LCDLCALC_01383 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LCDLCALC_01384 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LCDLCALC_01385 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LCDLCALC_01386 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LCDLCALC_01387 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LCDLCALC_01388 4.1e-90 S Short repeat of unknown function (DUF308)
LCDLCALC_01389 6.2e-165 rapZ S Displays ATPase and GTPase activities
LCDLCALC_01390 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LCDLCALC_01391 2.1e-171 whiA K May be required for sporulation
LCDLCALC_01392 6.7e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LCDLCALC_01393 0.0 S SH3-like domain
LCDLCALC_01394 4.9e-111 ybbL S ABC transporter, ATP-binding protein
LCDLCALC_01395 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
LCDLCALC_01396 3.1e-48 S Domain of unknown function (DUF4811)
LCDLCALC_01397 1.4e-262 lmrB EGP Major facilitator Superfamily
LCDLCALC_01398 4.2e-77 K MerR HTH family regulatory protein
LCDLCALC_01399 3.1e-139 S Cysteine-rich secretory protein family
LCDLCALC_01400 4.6e-274 ycaM E amino acid
LCDLCALC_01401 2.8e-290
LCDLCALC_01403 3.3e-189 cggR K Putative sugar-binding domain
LCDLCALC_01404 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LCDLCALC_01405 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LCDLCALC_01406 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LCDLCALC_01407 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
LCDLCALC_01408 1.2e-94
LCDLCALC_01409 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
LCDLCALC_01410 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LCDLCALC_01411 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LCDLCALC_01412 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
LCDLCALC_01413 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
LCDLCALC_01414 2e-163 murB 1.3.1.98 M Cell wall formation
LCDLCALC_01415 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LCDLCALC_01416 1.3e-129 potB P ABC transporter permease
LCDLCALC_01417 4.8e-127 potC P ABC transporter permease
LCDLCALC_01418 7.3e-208 potD P ABC transporter
LCDLCALC_01419 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LCDLCALC_01420 2e-172 ybbR S YbbR-like protein
LCDLCALC_01421 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCDLCALC_01422 1.4e-147 S hydrolase
LCDLCALC_01423 1.8e-75 K Penicillinase repressor
LCDLCALC_01424 1.6e-118
LCDLCALC_01425 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LCDLCALC_01426 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LCDLCALC_01427 8.3e-143 licT K CAT RNA binding domain
LCDLCALC_01428 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
LCDLCALC_01429 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LCDLCALC_01430 1e-149 D Alpha beta
LCDLCALC_01431 1.9e-47 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
LCDLCALC_01432 2.6e-50 2.7.7.65 T GGDEF domain
LCDLCALC_01433 1.5e-81 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LCDLCALC_01435 2e-310 E Amino acid permease
LCDLCALC_01437 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LCDLCALC_01438 3.5e-101 ylbE GM NAD(P)H-binding
LCDLCALC_01439 7.6e-94 S VanZ like family
LCDLCALC_01440 8.9e-133 yebC K Transcriptional regulatory protein
LCDLCALC_01441 1.7e-179 comGA NU Type II IV secretion system protein
LCDLCALC_01442 1.7e-171 comGB NU type II secretion system
LCDLCALC_01443 3.1e-43 comGC U competence protein ComGC
LCDLCALC_01444 1.8e-69
LCDLCALC_01445 2.3e-41
LCDLCALC_01446 3.8e-77 comGF U Putative Competence protein ComGF
LCDLCALC_01447 1.6e-21
LCDLCALC_01448 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
LCDLCALC_01449 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LCDLCALC_01451 1.2e-149 L Belongs to the 'phage' integrase family
LCDLCALC_01452 5e-08 S Pfam:DUF955
LCDLCALC_01453 2.2e-25 K Helix-turn-helix domain
LCDLCALC_01454 1.3e-20 XK27_07105 K Helix-turn-helix XRE-family like proteins
LCDLCALC_01455 1.1e-29 K Helix-turn-helix domain
LCDLCALC_01457 2.2e-09 S Arc-like DNA binding domain
LCDLCALC_01459 4e-21 K Conserved phage C-terminus (Phg_2220_C)
LCDLCALC_01460 1.5e-26 S Domain of unknown function (DUF771)
LCDLCALC_01468 3.6e-34 S Phage derived protein Gp49-like (DUF891)
LCDLCALC_01469 7.1e-35 K Helix-turn-helix XRE-family like proteins
LCDLCALC_01470 1.1e-188 L N-6 DNA Methylase
LCDLCALC_01471 2.2e-26 S Type I restriction modification DNA specificity domain
LCDLCALC_01472 5.7e-11 S Single-strand binding protein family
LCDLCALC_01478 3.9e-24 S SLAP domain
LCDLCALC_01479 1.4e-24 srtA 3.4.22.70 M sortase family
LCDLCALC_01481 6e-42 M domain protein
LCDLCALC_01482 6.8e-15 S SLAP domain
LCDLCALC_01484 1.5e-80
LCDLCALC_01485 1.6e-73 marR K Transcriptional regulator, MarR family
LCDLCALC_01486 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LCDLCALC_01487 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCDLCALC_01488 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCDLCALC_01489 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCDLCALC_01490 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
LCDLCALC_01491 2.9e-107 IQ reductase
LCDLCALC_01492 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LCDLCALC_01493 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LCDLCALC_01494 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
LCDLCALC_01495 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
LCDLCALC_01496 3.3e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LCDLCALC_01497 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
LCDLCALC_01498 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LCDLCALC_01499 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LCDLCALC_01500 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCDLCALC_01503 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
LCDLCALC_01504 1.3e-273 E amino acid
LCDLCALC_01505 0.0 L Helicase C-terminal domain protein
LCDLCALC_01506 4.8e-205 pbpX1 V Beta-lactamase
LCDLCALC_01507 5.1e-226 N Uncharacterized conserved protein (DUF2075)
LCDLCALC_01508 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LCDLCALC_01509 1e-15 S Domain of Unknown Function with PDB structure (DUF3850)
LCDLCALC_01511 2.5e-89 M Protein of unknown function (DUF3737)
LCDLCALC_01512 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
LCDLCALC_01513 7.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
LCDLCALC_01514 7.7e-67 S SdpI/YhfL protein family
LCDLCALC_01515 3.6e-103 K Transcriptional regulatory protein, C terminal
LCDLCALC_01516 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
LCDLCALC_01517 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LCDLCALC_01518 1.1e-104 vanZ V VanZ like family
LCDLCALC_01519 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
LCDLCALC_01520 4.9e-217 EGP Major facilitator Superfamily
LCDLCALC_01521 6.6e-195 ampC V Beta-lactamase
LCDLCALC_01524 8.4e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
LCDLCALC_01525 1.7e-113 tdk 2.7.1.21 F thymidine kinase
LCDLCALC_01526 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LCDLCALC_01527 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LCDLCALC_01528 1.9e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LCDLCALC_01529 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LCDLCALC_01530 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
LCDLCALC_01531 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCDLCALC_01532 4.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LCDLCALC_01533 1.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCDLCALC_01534 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LCDLCALC_01535 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LCDLCALC_01536 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LCDLCALC_01537 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LCDLCALC_01538 2e-30 ywzB S Protein of unknown function (DUF1146)
LCDLCALC_01539 1.2e-177 mbl D Cell shape determining protein MreB Mrl
LCDLCALC_01540 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LCDLCALC_01541 3.3e-33 S Protein of unknown function (DUF2969)
LCDLCALC_01542 4.7e-216 rodA D Belongs to the SEDS family
LCDLCALC_01543 1.8e-78 usp6 T universal stress protein
LCDLCALC_01544 8.4e-39
LCDLCALC_01545 6.3e-238 rarA L recombination factor protein RarA
LCDLCALC_01546 1.3e-84 yueI S Protein of unknown function (DUF1694)
LCDLCALC_01547 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LCDLCALC_01548 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LCDLCALC_01549 6.2e-213 iscS2 2.8.1.7 E Aminotransferase class V
LCDLCALC_01550 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCDLCALC_01551 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
LCDLCALC_01552 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LCDLCALC_01553 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LCDLCALC_01554 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
LCDLCALC_01555 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
LCDLCALC_01556 1.5e-94 S Protein of unknown function (DUF3990)
LCDLCALC_01557 6.5e-44
LCDLCALC_01559 0.0 3.6.3.8 P P-type ATPase
LCDLCALC_01560 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
LCDLCALC_01561 2.5e-52
LCDLCALC_01562 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LCDLCALC_01563 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LCDLCALC_01564 5.7e-126 S Haloacid dehalogenase-like hydrolase
LCDLCALC_01565 2.3e-108 radC L DNA repair protein
LCDLCALC_01566 2.4e-176 mreB D cell shape determining protein MreB
LCDLCALC_01567 2e-147 mreC M Involved in formation and maintenance of cell shape
LCDLCALC_01568 2.7e-94 mreD
LCDLCALC_01570 6.4e-54 S Protein of unknown function (DUF3397)
LCDLCALC_01571 6.3e-78 mraZ K Belongs to the MraZ family
LCDLCALC_01572 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LCDLCALC_01573 1.8e-54 ftsL D Cell division protein FtsL
LCDLCALC_01574 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LCDLCALC_01575 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LCDLCALC_01576 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LCDLCALC_01577 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LCDLCALC_01578 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LCDLCALC_01579 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LCDLCALC_01580 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LCDLCALC_01581 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LCDLCALC_01582 1.7e-45 yggT S YGGT family
LCDLCALC_01583 5.7e-149 ylmH S S4 domain protein
LCDLCALC_01584 2.8e-74 gpsB D DivIVA domain protein
LCDLCALC_01585 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LCDLCALC_01586 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
LCDLCALC_01587 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
LCDLCALC_01588 6.7e-37
LCDLCALC_01589 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LCDLCALC_01590 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
LCDLCALC_01591 5.4e-56 XK27_04120 S Putative amino acid metabolism
LCDLCALC_01592 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LCDLCALC_01593 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
LCDLCALC_01594 8.3e-106 S Repeat protein
LCDLCALC_01595 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LCDLCALC_01596 1.6e-294 L Nuclease-related domain
LCDLCALC_01597 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
LCDLCALC_01598 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LCDLCALC_01599 3.5e-32 ykzG S Belongs to the UPF0356 family
LCDLCALC_01600 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LCDLCALC_01601 0.0 typA T GTP-binding protein TypA
LCDLCALC_01602 5.9e-211 ftsW D Belongs to the SEDS family
LCDLCALC_01603 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
LCDLCALC_01604 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
LCDLCALC_01605 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LCDLCALC_01606 2.4e-187 ylbL T Belongs to the peptidase S16 family
LCDLCALC_01607 3.1e-79 comEA L Competence protein ComEA
LCDLCALC_01608 0.0 comEC S Competence protein ComEC
LCDLCALC_01609 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
LCDLCALC_01610 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
LCDLCALC_01611 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LCDLCALC_01612 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LCDLCALC_01613 1.3e-148
LCDLCALC_01614 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LCDLCALC_01615 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LCDLCALC_01616 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LCDLCALC_01617 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
LCDLCALC_01618 7.8e-39 yjeM E Amino Acid
LCDLCALC_01619 3.4e-175 yjeM E Amino Acid
LCDLCALC_01620 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LCDLCALC_01621 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
LCDLCALC_01622 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LCDLCALC_01623 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LCDLCALC_01624 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LCDLCALC_01625 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LCDLCALC_01626 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LCDLCALC_01627 2.7e-216 aspC 2.6.1.1 E Aminotransferase
LCDLCALC_01628 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LCDLCALC_01629 2.1e-194 pbpX1 V Beta-lactamase
LCDLCALC_01630 1.2e-299 I Protein of unknown function (DUF2974)
LCDLCALC_01631 3.6e-39 C FMN_bind
LCDLCALC_01632 1.5e-81
LCDLCALC_01633 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
LCDLCALC_01634 2e-85 alkD L DNA alkylation repair enzyme
LCDLCALC_01635 9.9e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LCDLCALC_01636 6.4e-128 K UTRA domain
LCDLCALC_01637 1e-54 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
LCDLCALC_01638 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
LCDLCALC_01639 2e-169 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LCDLCALC_01640 3.5e-70 S Domain of unknown function (DUF3284)
LCDLCALC_01641 2.7e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LCDLCALC_01642 3.3e-119 gmuR K UTRA
LCDLCALC_01643 3.7e-223 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LCDLCALC_01644 2e-274 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LCDLCALC_01645 9.2e-137 ypbG 2.7.1.2 GK ROK family
LCDLCALC_01646 2e-49 C nitroreductase
LCDLCALC_01647 7.5e-91 S Domain of unknown function (DUF4767)
LCDLCALC_01648 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LCDLCALC_01649 2.2e-151 yitS S Uncharacterised protein, DegV family COG1307
LCDLCALC_01650 4.6e-100 3.6.1.27 I Acid phosphatase homologues
LCDLCALC_01651 3.2e-178 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LCDLCALC_01653 1.6e-172 MA20_14895 S Conserved hypothetical protein 698
LCDLCALC_01654 6.3e-26 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
LCDLCALC_01655 1.9e-30 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
LCDLCALC_01656 1e-284 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
LCDLCALC_01657 1.2e-30 copZ C Heavy-metal-associated domain
LCDLCALC_01658 1.6e-78 dps P Belongs to the Dps family
LCDLCALC_01659 1.9e-86 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
LCDLCALC_01660 5.8e-129 yobV1 K WYL domain
LCDLCALC_01661 1.8e-55 S pyridoxamine 5-phosphate
LCDLCALC_01662 3.8e-84 dps P Belongs to the Dps family
LCDLCALC_01663 1.1e-67 L Transposase and inactivated derivatives, IS30 family
LCDLCALC_01664 2.2e-14 L Transposase and inactivated derivatives, IS30 family
LCDLCALC_01665 2.2e-12 L Transposase and inactivated derivatives, IS30 family
LCDLCALC_01666 2.4e-10 L Psort location Cytoplasmic, score
LCDLCALC_01667 2.2e-87 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
LCDLCALC_01668 2.8e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LCDLCALC_01669 4.5e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
LCDLCALC_01670 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
LCDLCALC_01671 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LCDLCALC_01673 1.9e-237 brnQ U Component of the transport system for branched-chain amino acids
LCDLCALC_01674 8.2e-24 S Alpha beta hydrolase
LCDLCALC_01675 1.4e-273 lsa S ABC transporter
LCDLCALC_01676 2.6e-112 ltrA S Bacterial low temperature requirement A protein (LtrA)
LCDLCALC_01677 7.4e-120 3.6.1.55 F NUDIX domain
LCDLCALC_01678 1.8e-243 brnQ U Component of the transport system for branched-chain amino acids
LCDLCALC_01679 0.0 L Plasmid pRiA4b ORF-3-like protein
LCDLCALC_01680 3.2e-65 K HxlR family
LCDLCALC_01681 3.9e-47
LCDLCALC_01682 4.2e-107 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
LCDLCALC_01683 4.7e-99 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
LCDLCALC_01684 3.4e-62 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LCDLCALC_01685 1.3e-07 S Protein of unknown function (DUF3021)
LCDLCALC_01687 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LCDLCALC_01688 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
LCDLCALC_01689 1.4e-36 S Cytochrome B5
LCDLCALC_01690 6e-168 arbZ I Phosphate acyltransferases
LCDLCALC_01691 1.6e-182 arbY M Glycosyl transferase family 8
LCDLCALC_01692 5e-184 arbY M Glycosyl transferase family 8
LCDLCALC_01693 5e-156 arbx M Glycosyl transferase family 8
LCDLCALC_01694 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
LCDLCALC_01696 4.8e-131 K response regulator
LCDLCALC_01697 2.2e-305 vicK 2.7.13.3 T Histidine kinase
LCDLCALC_01698 1.6e-257 yycH S YycH protein
LCDLCALC_01699 3.4e-149 yycI S YycH protein
LCDLCALC_01700 4.1e-147 vicX 3.1.26.11 S domain protein
LCDLCALC_01701 1.6e-161 htrA 3.4.21.107 O serine protease
LCDLCALC_01702 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LCDLCALC_01703 3.9e-201 XK27_00915 C Luciferase-like monooxygenase
LCDLCALC_01704 6.5e-87 K GNAT family
LCDLCALC_01705 1.5e-123 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
LCDLCALC_01707 1.5e-36
LCDLCALC_01708 9.5e-289 P ABC transporter
LCDLCALC_01709 2.4e-284 V ABC-type multidrug transport system, ATPase and permease components
LCDLCALC_01710 1.9e-248 yifK E Amino acid permease
LCDLCALC_01711 9.1e-178 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LCDLCALC_01712 2.2e-90 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LCDLCALC_01713 0.0 aha1 P E1-E2 ATPase
LCDLCALC_01714 1.9e-175 F DNA/RNA non-specific endonuclease
LCDLCALC_01715 2e-160 metQ2 P Belongs to the nlpA lipoprotein family
LCDLCALC_01716 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LCDLCALC_01717 2e-73 metI P ABC transporter permease
LCDLCALC_01718 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LCDLCALC_01719 1.9e-261 frdC 1.3.5.4 C FAD binding domain
LCDLCALC_01720 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LCDLCALC_01721 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
LCDLCALC_01722 8.4e-153 ydjP I Alpha/beta hydrolase family
LCDLCALC_01723 7.7e-194 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LCDLCALC_01724 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
LCDLCALC_01725 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
LCDLCALC_01726 2.4e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
LCDLCALC_01727 9.3e-72 yeaL S Protein of unknown function (DUF441)
LCDLCALC_01728 7e-22
LCDLCALC_01729 3.6e-146 cbiQ P cobalt transport
LCDLCALC_01730 0.0 ykoD P ABC transporter, ATP-binding protein
LCDLCALC_01731 1.5e-95 S UPF0397 protein
LCDLCALC_01732 2.9e-66 S Domain of unknown function DUF1828
LCDLCALC_01733 5.5e-09
LCDLCALC_01734 1.5e-50
LCDLCALC_01735 2.6e-177 citR K Putative sugar-binding domain
LCDLCALC_01736 6.5e-249 yjjP S Putative threonine/serine exporter
LCDLCALC_01738 5.9e-37 M domain protein
LCDLCALC_01739 4.1e-26 L Transposase
LCDLCALC_01740 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LCDLCALC_01741 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
LCDLCALC_01742 8.5e-60
LCDLCALC_01743 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LCDLCALC_01744 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LCDLCALC_01745 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
LCDLCALC_01746 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LCDLCALC_01747 1.1e-220 patA 2.6.1.1 E Aminotransferase
LCDLCALC_01749 1e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LCDLCALC_01750 1e-34 S reductase
LCDLCALC_01751 1.2e-91 S reductase
LCDLCALC_01752 5.8e-149 yxeH S hydrolase
LCDLCALC_01753 8e-182 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCDLCALC_01754 2.4e-243 yfnA E Amino Acid
LCDLCALC_01755 1.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
LCDLCALC_01756 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LCDLCALC_01757 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LCDLCALC_01758 1.4e-294 I Acyltransferase
LCDLCALC_01759 5.8e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LCDLCALC_01760 1.6e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LCDLCALC_01761 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
LCDLCALC_01762 2.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LCDLCALC_01763 4.3e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LCDLCALC_01764 2.3e-23 S Protein of unknown function (DUF2929)
LCDLCALC_01765 0.0 dnaE 2.7.7.7 L DNA polymerase
LCDLCALC_01766 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LCDLCALC_01767 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LCDLCALC_01768 1.9e-169 cvfB S S1 domain
LCDLCALC_01769 2.6e-166 xerD D recombinase XerD
LCDLCALC_01770 7.7e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LCDLCALC_01771 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LCDLCALC_01772 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LCDLCALC_01773 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LCDLCALC_01774 2.9e-43 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LCDLCALC_01775 2.1e-52 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LCDLCALC_01776 2.7e-18 M Lysin motif
LCDLCALC_01777 3.2e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LCDLCALC_01778 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
LCDLCALC_01779 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LCDLCALC_01780 3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LCDLCALC_01781 2.5e-13 S Tetratricopeptide repeat protein
LCDLCALC_01782 2e-186 S Tetratricopeptide repeat protein
LCDLCALC_01783 5.8e-288 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCDLCALC_01784 2.6e-225 V ABC transporter transmembrane region
LCDLCALC_01785 3e-48 V ABC transporter transmembrane region
LCDLCALC_01786 5.2e-91 speG J Acetyltransferase (GNAT) domain
LCDLCALC_01787 2.9e-226 L Transposase
LCDLCALC_01788 3.5e-80 S AAA domain
LCDLCALC_01789 1.2e-40 3.6.1.55 F NUDIX domain
LCDLCALC_01790 1.6e-145 2.4.2.3 F Phosphorylase superfamily
LCDLCALC_01791 2.2e-149 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
LCDLCALC_01792 7.6e-100 yagE E Amino acid permease
LCDLCALC_01793 5.6e-34 yagE E Amino acid permease
LCDLCALC_01794 7.3e-86 3.4.21.96 S SLAP domain
LCDLCALC_01795 7.9e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCDLCALC_01796 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LCDLCALC_01797 1.2e-107 hlyIII S protein, hemolysin III
LCDLCALC_01798 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
LCDLCALC_01799 7.1e-36 yozE S Belongs to the UPF0346 family
LCDLCALC_01800 1.1e-66 yjcE P NhaP-type Na H and K H
LCDLCALC_01801 1.5e-40 yjcE P Sodium proton antiporter
LCDLCALC_01802 1.9e-94 yjcE P Sodium proton antiporter
LCDLCALC_01803 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LCDLCALC_01804 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LCDLCALC_01805 5.8e-152 dprA LU DNA protecting protein DprA
LCDLCALC_01806 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCDLCALC_01807 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LCDLCALC_01808 2.2e-141 xerC D Phage integrase, N-terminal SAM-like domain
LCDLCALC_01809 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LCDLCALC_01810 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LCDLCALC_01811 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
LCDLCALC_01812 1.4e-86 C Aldo keto reductase
LCDLCALC_01813 3.8e-48 M LysM domain protein
LCDLCALC_01814 2.9e-15 M LysM domain protein
LCDLCALC_01815 1.4e-15 S cog cog1373
LCDLCALC_01816 1.4e-156 hipB K Helix-turn-helix
LCDLCALC_01817 6e-151 I alpha/beta hydrolase fold
LCDLCALC_01818 1.4e-110 yjbF S SNARE associated Golgi protein
LCDLCALC_01819 7.5e-100 J Acetyltransferase (GNAT) domain
LCDLCALC_01820 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LCDLCALC_01821 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
LCDLCALC_01822 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
LCDLCALC_01823 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
LCDLCALC_01824 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
LCDLCALC_01825 8e-141 L An automated process has identified a potential problem with this gene model
LCDLCALC_01826 4.4e-118 L hmm pf00665
LCDLCALC_01827 1.4e-98 L Helix-turn-helix domain
LCDLCALC_01828 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
LCDLCALC_01829 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCDLCALC_01830 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCDLCALC_01831 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
LCDLCALC_01832 1.4e-115 mmuP E amino acid
LCDLCALC_01833 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
LCDLCALC_01834 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
LCDLCALC_01835 1.7e-284 E Amino acid permease
LCDLCALC_01836 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
LCDLCALC_01837 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
LCDLCALC_01838 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
LCDLCALC_01839 9.2e-36 L An automated process has identified a potential problem with this gene model
LCDLCALC_01840 8.4e-25 G Peptidase_C39 like family
LCDLCALC_01841 2.8e-162 M NlpC/P60 family
LCDLCALC_01842 6.5e-91 G Peptidase_C39 like family
LCDLCALC_01843 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
LCDLCALC_01844 2.8e-77 P Cobalt transport protein
LCDLCALC_01845 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
LCDLCALC_01846 7.9e-174 K helix_turn_helix, arabinose operon control protein
LCDLCALC_01847 8.3e-157 htpX O Belongs to the peptidase M48B family
LCDLCALC_01848 5.1e-96 lemA S LemA family
LCDLCALC_01849 9.9e-82 C Flavodoxin
LCDLCALC_01850 0.0 uvrA3 L excinuclease ABC, A subunit
LCDLCALC_01851 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
LCDLCALC_01852 2.1e-114 3.6.1.27 I Acid phosphatase homologues
LCDLCALC_01853 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
LCDLCALC_01854 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LCDLCALC_01855 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
LCDLCALC_01856 9.3e-204 pbpX1 V Beta-lactamase
LCDLCALC_01857 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
LCDLCALC_01858 7.5e-95 S ECF-type riboflavin transporter, S component
LCDLCALC_01859 1.3e-229 S Putative peptidoglycan binding domain
LCDLCALC_01860 9e-83 K Acetyltransferase (GNAT) domain
LCDLCALC_01861 1.7e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LCDLCALC_01862 2.5e-191 yrvN L AAA C-terminal domain
LCDLCALC_01863 5.7e-65 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LCDLCALC_01864 6.8e-153 treB G phosphotransferase system
LCDLCALC_01865 4.5e-111 treB G phosphotransferase system
LCDLCALC_01866 1.2e-100 treR K UTRA
LCDLCALC_01867 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
LCDLCALC_01868 5.7e-18
LCDLCALC_01869 1.5e-239 G Bacterial extracellular solute-binding protein
LCDLCALC_01870 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
LCDLCALC_01871 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
LCDLCALC_01873 0.0 S SLAP domain
LCDLCALC_01874 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
LCDLCALC_01875 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
LCDLCALC_01876 3.4e-42 S RloB-like protein
LCDLCALC_01877 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
LCDLCALC_01878 5.7e-99 3.1.21.3 V Type I restriction modification DNA specificity domain
LCDLCALC_01879 1.2e-63 S SIR2-like domain
LCDLCALC_01880 3.2e-10 S Domain of unknown function DUF87
LCDLCALC_01881 2e-75 S cog cog0433
LCDLCALC_01882 1.9e-110 F DNA/RNA non-specific endonuclease
LCDLCALC_01883 2.7e-34 S YSIRK type signal peptide
LCDLCALC_01885 5.5e-53
LCDLCALC_01886 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LCDLCALC_01887 3.1e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LCDLCALC_01888 9.6e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LCDLCALC_01889 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LCDLCALC_01890 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
LCDLCALC_01891 0.0 FbpA K Fibronectin-binding protein
LCDLCALC_01892 1.1e-66
LCDLCALC_01893 1.3e-159 degV S EDD domain protein, DegV family
LCDLCALC_01894 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LCDLCALC_01895 5.4e-203 xerS L Belongs to the 'phage' integrase family
LCDLCALC_01896 4.1e-67
LCDLCALC_01897 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
LCDLCALC_01898 5.8e-211 M Glycosyl hydrolases family 25
LCDLCALC_01899 2.2e-89
LCDLCALC_01900 3e-09 isdH M Iron Transport-associated domain
LCDLCALC_01901 6.3e-123 M Iron Transport-associated domain
LCDLCALC_01902 8.7e-159 isdE P Periplasmic binding protein
LCDLCALC_01903 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCDLCALC_01904 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
LCDLCALC_01905 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LCDLCALC_01906 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
LCDLCALC_01907 1.3e-38 S RelB antitoxin
LCDLCALC_01908 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
LCDLCALC_01909 0.0 S membrane
LCDLCALC_01910 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
LCDLCALC_01911 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LCDLCALC_01912 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LCDLCALC_01913 4e-119 gluP 3.4.21.105 S Rhomboid family
LCDLCALC_01914 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
LCDLCALC_01915 1.5e-65 yqhL P Rhodanese-like protein
LCDLCALC_01916 1.5e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LCDLCALC_01917 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
LCDLCALC_01918 2e-263 glnA 6.3.1.2 E glutamine synthetase
LCDLCALC_01919 6.7e-170
LCDLCALC_01920 6e-148
LCDLCALC_01921 1.9e-21
LCDLCALC_01924 2.7e-34
LCDLCALC_01925 1.2e-128 S interspecies interaction between organisms
LCDLCALC_01927 9.1e-10 K peptidyl-tyrosine sulfation
LCDLCALC_01928 7.1e-263 E ABC transporter, substratebinding protein
LCDLCALC_01929 3.7e-66 K Helix-turn-helix domain, rpiR family
LCDLCALC_01930 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
LCDLCALC_01931 8.4e-90 nanK GK ROK family
LCDLCALC_01932 2.3e-56 G Xylose isomerase domain protein TIM barrel
LCDLCALC_01933 1.9e-121 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LCDLCALC_01934 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCDLCALC_01935 1.1e-59 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
LCDLCALC_01936 1.7e-36 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
LCDLCALC_01937 2.9e-109 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LCDLCALC_01938 7.7e-10 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LCDLCALC_01939 3.6e-88 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LCDLCALC_01940 2.7e-224 L Transposase
LCDLCALC_01941 5.1e-106 fabK 1.3.1.9 S Nitronate monooxygenase
LCDLCALC_01942 1.6e-82 2.8.3.1 I Coenzyme A transferase
LCDLCALC_01943 5.8e-151 2.8.3.1 I Coenzyme A transferase
LCDLCALC_01944 3.7e-144 gltC_1 3.1.3.48 K LysR substrate binding domain
LCDLCALC_01945 1.5e-54 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LCDLCALC_01946 3.2e-75 S ECF transporter, substrate-specific component
LCDLCALC_01947 3.8e-80 coaA 2.7.1.33 F Pantothenic acid kinase
LCDLCALC_01948 1.4e-31 O OsmC-like protein
LCDLCALC_01950 1.5e-36 oppA E ABC transporter substrate-binding protein
LCDLCALC_01951 5.2e-140 L An automated process has identified a potential problem with this gene model
LCDLCALC_01952 4e-57 K Helix-turn-helix domain
LCDLCALC_01953 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LCDLCALC_01954 1.1e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
LCDLCALC_01955 2.8e-182 K Transcriptional regulator
LCDLCALC_01956 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LCDLCALC_01957 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LCDLCALC_01958 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LCDLCALC_01959 0.0 snf 2.7.11.1 KL domain protein
LCDLCALC_01960 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
LCDLCALC_01961 3.4e-79
LCDLCALC_01962 1e-242 cpdA S Calcineurin-like phosphoesterase
LCDLCALC_01963 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LCDLCALC_01964 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LCDLCALC_01965 1e-107 ypsA S Belongs to the UPF0398 family
LCDLCALC_01966 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LCDLCALC_01967 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
LCDLCALC_01968 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LCDLCALC_01969 1.3e-114 dnaD L DnaD domain protein
LCDLCALC_01970 5.8e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
LCDLCALC_01971 2.4e-89 ypmB S Protein conserved in bacteria
LCDLCALC_01972 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LCDLCALC_01973 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LCDLCALC_01974 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LCDLCALC_01975 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
LCDLCALC_01976 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
LCDLCALC_01977 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
LCDLCALC_01978 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LCDLCALC_01979 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
LCDLCALC_01980 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
LCDLCALC_01981 9.7e-169
LCDLCALC_01982 7.5e-143
LCDLCALC_01983 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LCDLCALC_01984 1.4e-26
LCDLCALC_01985 6.7e-145
LCDLCALC_01986 5.1e-137
LCDLCALC_01987 4.5e-141
LCDLCALC_01988 9.6e-124 skfE V ATPases associated with a variety of cellular activities
LCDLCALC_01989 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
LCDLCALC_01990 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LCDLCALC_01991 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LCDLCALC_01992 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
LCDLCALC_01993 4.8e-81 mutT 3.6.1.55 F NUDIX domain
LCDLCALC_01994 1.4e-127 S Peptidase family M23
LCDLCALC_01995 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LCDLCALC_01996 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LCDLCALC_01997 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LCDLCALC_01998 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LCDLCALC_01999 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
LCDLCALC_02000 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LCDLCALC_02001 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LCDLCALC_02002 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
LCDLCALC_02003 3.5e-71 yqeY S YqeY-like protein
LCDLCALC_02004 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LCDLCALC_02005 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LCDLCALC_02006 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
LCDLCALC_02007 1.3e-221 L Transposase
LCDLCALC_02008 4e-40 S CRISPR-associated protein (Cas_Csn2)
LCDLCALC_02009 8.3e-40 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LCDLCALC_02010 3e-130 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LCDLCALC_02011 3.7e-92 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LCDLCALC_02012 1.8e-81 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LCDLCALC_02013 1.3e-116 S Peptidase family M23
LCDLCALC_02014 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCDLCALC_02016 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCDLCALC_02017 9.4e-118
LCDLCALC_02018 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LCDLCALC_02019 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
LCDLCALC_02020 2.6e-280 thrC 4.2.3.1 E Threonine synthase
LCDLCALC_02021 4.4e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
LCDLCALC_02022 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
LCDLCALC_02023 1.2e-224 L Transposase
LCDLCALC_02024 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
LCDLCALC_02025 2e-157 S reductase
LCDLCALC_02026 9.3e-35
LCDLCALC_02027 0.0 L PLD-like domain
LCDLCALC_02028 4.8e-42 S SnoaL-like domain
LCDLCALC_02029 5.4e-53 hipB K sequence-specific DNA binding
LCDLCALC_02030 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
LCDLCALC_02031 3.4e-27
LCDLCALC_02032 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
LCDLCALC_02033 2.6e-275 V ABC-type multidrug transport system, ATPase and permease components
LCDLCALC_02034 1e-84 L Transposase
LCDLCALC_02035 1.4e-94
LCDLCALC_02036 5.4e-162 ybiR P Citrate transporter
LCDLCALC_02037 2e-70 S Iron-sulphur cluster biosynthesis
LCDLCALC_02038 1.9e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
LCDLCALC_02039 1.2e-17
LCDLCALC_02040 1.1e-07 S Uncharacterised protein family (UPF0236)
LCDLCALC_02041 4.5e-189 ydaM M Glycosyl transferase
LCDLCALC_02042 4e-177 G Glycosyl hydrolases family 8
LCDLCALC_02043 1e-119 yfbR S HD containing hydrolase-like enzyme
LCDLCALC_02044 6.4e-159 L HNH nucleases
LCDLCALC_02045 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
LCDLCALC_02046 9e-98
LCDLCALC_02047 4.9e-108 K LysR substrate binding domain
LCDLCALC_02048 1e-20
LCDLCALC_02049 2.3e-215 S Sterol carrier protein domain
LCDLCALC_02050 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LCDLCALC_02051 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
LCDLCALC_02052 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LCDLCALC_02053 5.7e-233 arcA 3.5.3.6 E Arginine
LCDLCALC_02054 9e-137 lysR5 K LysR substrate binding domain
LCDLCALC_02055 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
LCDLCALC_02056 1e-48 S Metal binding domain of Ada
LCDLCALC_02057 2.3e-43 ybhL S Belongs to the BI1 family
LCDLCALC_02059 1.2e-210 S Bacterial protein of unknown function (DUF871)
LCDLCALC_02060 3.6e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCDLCALC_02061 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LCDLCALC_02062 1.5e-102 srtA 3.4.22.70 M sortase family
LCDLCALC_02063 2.1e-173 M Glycosyl hydrolases family 25
LCDLCALC_02064 5e-29
LCDLCALC_02065 7.9e-19
LCDLCALC_02067 1.1e-07
LCDLCALC_02068 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
LCDLCALC_02069 7.1e-38
LCDLCALC_02075 1.6e-36
LCDLCALC_02076 1.1e-08
LCDLCALC_02077 1.7e-125 Z012_12235 S Baseplate J-like protein
LCDLCALC_02078 9.5e-33
LCDLCALC_02079 1.2e-48
LCDLCALC_02080 5.7e-104
LCDLCALC_02081 2.1e-46
LCDLCALC_02082 1.2e-58 M LysM domain
LCDLCALC_02083 0.0 3.4.14.13 M Phage tail tape measure protein TP901
LCDLCALC_02085 9e-27
LCDLCALC_02086 4e-56
LCDLCALC_02087 9.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
LCDLCALC_02088 8e-57
LCDLCALC_02089 2.9e-45
LCDLCALC_02090 1.5e-75
LCDLCALC_02091 2.1e-30 S Protein of unknown function (DUF4054)
LCDLCALC_02092 3.5e-142 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
LCDLCALC_02093 1.6e-58
LCDLCALC_02094 3.9e-87 S Uncharacterized protein conserved in bacteria (DUF2213)
LCDLCALC_02095 1.1e-07 S Lysin motif
LCDLCALC_02096 1e-97 S Phage Mu protein F like protein
LCDLCALC_02097 7e-142 S Protein of unknown function (DUF1073)
LCDLCALC_02098 1.8e-230 S Terminase-like family
LCDLCALC_02099 1.5e-28 L Terminase small subunit
LCDLCALC_02100 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
LCDLCALC_02101 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
LCDLCALC_02109 2.1e-14
LCDLCALC_02110 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
LCDLCALC_02116 2.3e-49 dnaC L IstB-like ATP binding protein
LCDLCALC_02117 2.7e-34 S Conserved phage C-terminus (Phg_2220_C)
LCDLCALC_02118 6.5e-57 S Protein of unknown function (DUF1071)
LCDLCALC_02123 1.8e-07 K Helix-turn-helix XRE-family like proteins
LCDLCALC_02124 7.2e-10
LCDLCALC_02128 4.3e-98 S AntA/AntB antirepressor
LCDLCALC_02129 2.9e-12
LCDLCALC_02134 1.3e-81 S DNA binding
LCDLCALC_02135 9.5e-12 K Helix-turn-helix XRE-family like proteins
LCDLCALC_02136 1.9e-22 K Cro/C1-type HTH DNA-binding domain
LCDLCALC_02137 3.3e-18 S Pfam:Peptidase_M78
LCDLCALC_02142 1.6e-20 S YjcQ protein
LCDLCALC_02143 4.2e-180 sip L Belongs to the 'phage' integrase family
LCDLCALC_02144 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LCDLCALC_02145 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LCDLCALC_02146 0.0 dnaK O Heat shock 70 kDa protein
LCDLCALC_02147 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LCDLCALC_02148 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LCDLCALC_02149 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LCDLCALC_02150 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LCDLCALC_02151 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LCDLCALC_02152 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LCDLCALC_02153 3.2e-47 rplGA J ribosomal protein
LCDLCALC_02154 8.8e-47 ylxR K Protein of unknown function (DUF448)
LCDLCALC_02155 1.4e-196 nusA K Participates in both transcription termination and antitermination
LCDLCALC_02156 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
LCDLCALC_02157 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LCDLCALC_02158 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LCDLCALC_02159 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LCDLCALC_02160 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
LCDLCALC_02161 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LCDLCALC_02162 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LCDLCALC_02163 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LCDLCALC_02164 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LCDLCALC_02165 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
LCDLCALC_02166 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
LCDLCALC_02167 2.9e-116 plsC 2.3.1.51 I Acyltransferase
LCDLCALC_02168 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
LCDLCALC_02169 0.0 pepO 3.4.24.71 O Peptidase family M13
LCDLCALC_02170 0.0 mdlB V ABC transporter
LCDLCALC_02171 0.0 mdlA V ABC transporter
LCDLCALC_02172 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
LCDLCALC_02173 3e-38 ynzC S UPF0291 protein
LCDLCALC_02174 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LCDLCALC_02175 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
LCDLCALC_02176 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
LCDLCALC_02177 4.6e-213 S SLAP domain
LCDLCALC_02178 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LCDLCALC_02179 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LCDLCALC_02180 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LCDLCALC_02181 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LCDLCALC_02182 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LCDLCALC_02183 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LCDLCALC_02184 2.7e-258 yfnA E amino acid
LCDLCALC_02185 0.0 V FtsX-like permease family
LCDLCALC_02186 4.1e-133 cysA V ABC transporter, ATP-binding protein
LCDLCALC_02187 3.4e-23
LCDLCALC_02189 2.5e-288 pipD E Dipeptidase
LCDLCALC_02190 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LCDLCALC_02191 0.0 smc D Required for chromosome condensation and partitioning
LCDLCALC_02192 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LCDLCALC_02193 2.1e-308 oppA E ABC transporter substrate-binding protein
LCDLCALC_02194 3.1e-240 oppA E ABC transporter substrate-binding protein
LCDLCALC_02195 9.7e-46 oppA E ABC transporter substrate-binding protein
LCDLCALC_02196 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
LCDLCALC_02197 2.6e-172 oppB P ABC transporter permease
LCDLCALC_02198 1.5e-170 oppF P Belongs to the ABC transporter superfamily
LCDLCALC_02199 1.1e-192 oppD P Belongs to the ABC transporter superfamily
LCDLCALC_02200 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCDLCALC_02201 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LCDLCALC_02202 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LCDLCALC_02203 7.6e-305 yloV S DAK2 domain fusion protein YloV
LCDLCALC_02204 4e-57 asp S Asp23 family, cell envelope-related function
LCDLCALC_02205 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LCDLCALC_02206 1.4e-30
LCDLCALC_02207 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
LCDLCALC_02208 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LCDLCALC_02209 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LCDLCALC_02210 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
LCDLCALC_02211 1.1e-138 stp 3.1.3.16 T phosphatase
LCDLCALC_02212 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCDLCALC_02213 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LCDLCALC_02214 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LCDLCALC_02215 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LCDLCALC_02216 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
LCDLCALC_02217 1.1e-77 6.3.3.2 S ASCH
LCDLCALC_02218 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
LCDLCALC_02219 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LCDLCALC_02220 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LCDLCALC_02221 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LCDLCALC_02222 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LCDLCALC_02223 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LCDLCALC_02224 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCDLCALC_02225 3.4e-71 yqhY S Asp23 family, cell envelope-related function
LCDLCALC_02226 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LCDLCALC_02227 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LCDLCALC_02228 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LCDLCALC_02229 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
LCDLCALC_02230 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCDLCALC_02231 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
LCDLCALC_02233 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
LCDLCALC_02234 4.3e-298 S Predicted membrane protein (DUF2207)
LCDLCALC_02235 1.2e-155 cinI S Serine hydrolase (FSH1)
LCDLCALC_02236 1e-205 M Glycosyl hydrolases family 25
LCDLCALC_02238 8.5e-178 I Carboxylesterase family
LCDLCALC_02239 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
LCDLCALC_02240 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
LCDLCALC_02241 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
LCDLCALC_02242 1.7e-148 S haloacid dehalogenase-like hydrolase
LCDLCALC_02243 7e-50
LCDLCALC_02244 1.9e-37
LCDLCALC_02245 1.2e-63 S Alpha beta hydrolase
LCDLCALC_02246 3.7e-19 S Alpha beta hydrolase
LCDLCALC_02247 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LCDLCALC_02248 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LCDLCALC_02249 7.1e-46
LCDLCALC_02250 3.1e-148 glcU U sugar transport
LCDLCALC_02251 3.7e-250 lctP C L-lactate permease
LCDLCALC_02252 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
LCDLCALC_02253 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LCDLCALC_02254 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LCDLCALC_02255 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LCDLCALC_02256 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LCDLCALC_02257 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LCDLCALC_02258 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LCDLCALC_02259 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LCDLCALC_02261 2e-57 clcA P chloride
LCDLCALC_02262 2.5e-115 L PFAM Integrase catalytic
LCDLCALC_02263 1.3e-284 lsa S ABC transporter
LCDLCALC_02264 2.4e-44
LCDLCALC_02265 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
LCDLCALC_02266 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LCDLCALC_02267 9.7e-52 S Iron-sulfur cluster assembly protein
LCDLCALC_02268 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LCDLCALC_02269 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LCDLCALC_02270 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
LCDLCALC_02271 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LCDLCALC_02272 3.3e-275 yjeM E Amino Acid
LCDLCALC_02273 5.8e-83 S Fic/DOC family
LCDLCALC_02274 3.1e-278
LCDLCALC_02275 3.2e-77
LCDLCALC_02276 2.3e-87 S Protein of unknown function (DUF805)
LCDLCALC_02277 5.6e-68 O OsmC-like protein
LCDLCALC_02278 9.4e-209 EGP Major facilitator Superfamily
LCDLCALC_02279 2.5e-215 sptS 2.7.13.3 T Histidine kinase
LCDLCALC_02280 1.7e-198 L Transposase and inactivated derivatives, IS30 family
LCDLCALC_02281 6.4e-71 scrR K Periplasmic binding protein domain
LCDLCALC_02282 5.5e-36
LCDLCALC_02283 2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
LCDLCALC_02284 1.1e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LCDLCALC_02285 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LCDLCALC_02286 0.0 lacZ 3.2.1.23 G -beta-galactosidase
LCDLCALC_02287 0.0 lacS G Transporter
LCDLCALC_02288 3.2e-165 lacR K Transcriptional regulator
LCDLCALC_02289 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
LCDLCALC_02290 3.5e-145 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
LCDLCALC_02291 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LCDLCALC_02292 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
LCDLCALC_02293 2e-106 K Transcriptional regulator, AbiEi antitoxin
LCDLCALC_02294 1.2e-188 K Periplasmic binding protein-like domain
LCDLCALC_02295 5.8e-73 S domain protein
LCDLCALC_02297 4.9e-251 ade 3.5.4.2 F Adenine deaminase C-terminal domain
LCDLCALC_02298 3e-145 potD2 P ABC transporter
LCDLCALC_02299 1.6e-135 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LCDLCALC_02300 2.2e-108 potC3 E Binding-protein-dependent transport system inner membrane component

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)