ORF_ID e_value Gene_name EC_number CAZy COGs Description
HCHLGBMO_00001 9.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCHLGBMO_00002 3.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCHLGBMO_00003 1.2e-189 ydaM M Glycosyl transferase
HCHLGBMO_00004 3.7e-175 G Glycosyl hydrolases family 8
HCHLGBMO_00005 1.1e-118 yfbR S HD containing hydrolase-like enzyme
HCHLGBMO_00006 1.4e-164 L HNH nucleases
HCHLGBMO_00007 1.4e-94
HCHLGBMO_00008 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HCHLGBMO_00009 9e-98
HCHLGBMO_00010 4.9e-108 K LysR substrate binding domain
HCHLGBMO_00011 1e-20
HCHLGBMO_00012 2.3e-215 S Sterol carrier protein domain
HCHLGBMO_00013 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HCHLGBMO_00014 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
HCHLGBMO_00015 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCHLGBMO_00016 4.4e-233 arcA 3.5.3.6 E Arginine
HCHLGBMO_00017 1.2e-136 lysR5 K LysR substrate binding domain
HCHLGBMO_00018 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HCHLGBMO_00019 1e-48 S Metal binding domain of Ada
HCHLGBMO_00020 2.3e-43 ybhL S Belongs to the BI1 family
HCHLGBMO_00022 1.2e-210 S Bacterial protein of unknown function (DUF871)
HCHLGBMO_00023 5.8e-203 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCHLGBMO_00024 0.0 dnaK O Heat shock 70 kDa protein
HCHLGBMO_00025 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCHLGBMO_00026 4.5e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCHLGBMO_00027 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HCHLGBMO_00028 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCHLGBMO_00029 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCHLGBMO_00030 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCHLGBMO_00031 3.2e-47 rplGA J ribosomal protein
HCHLGBMO_00032 8.8e-47 ylxR K Protein of unknown function (DUF448)
HCHLGBMO_00033 1.4e-196 nusA K Participates in both transcription termination and antitermination
HCHLGBMO_00034 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HCHLGBMO_00035 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCHLGBMO_00036 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCHLGBMO_00037 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HCHLGBMO_00038 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
HCHLGBMO_00039 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCHLGBMO_00040 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCHLGBMO_00041 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HCHLGBMO_00042 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCHLGBMO_00043 1.1e-136 rpsB J Belongs to the universal ribosomal protein uS2 family
HCHLGBMO_00044 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
HCHLGBMO_00045 2.9e-116 plsC 2.3.1.51 I Acyltransferase
HCHLGBMO_00046 9e-220 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HCHLGBMO_00047 0.0 pepO 3.4.24.71 O Peptidase family M13
HCHLGBMO_00048 0.0 mdlB V ABC transporter
HCHLGBMO_00049 0.0 mdlA V ABC transporter
HCHLGBMO_00050 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
HCHLGBMO_00051 3e-38 ynzC S UPF0291 protein
HCHLGBMO_00052 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCHLGBMO_00053 1.4e-20 E GDSL-like Lipase/Acylhydrolase family
HCHLGBMO_00054 8.5e-203 L Putative transposase DNA-binding domain
HCHLGBMO_00055 9.5e-112 L Resolvase, N-terminal
HCHLGBMO_00056 1.3e-114 E GDSL-like Lipase/Acylhydrolase family
HCHLGBMO_00057 1.5e-98 ung2 3.2.2.27 L Uracil-DNA glycosylase
HCHLGBMO_00058 6.7e-212 S SLAP domain
HCHLGBMO_00059 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCHLGBMO_00060 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HCHLGBMO_00061 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCHLGBMO_00062 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HCHLGBMO_00063 1.7e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCHLGBMO_00064 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCHLGBMO_00065 1.2e-258 yfnA E amino acid
HCHLGBMO_00066 3.5e-118 V FtsX-like permease family
HCHLGBMO_00067 4.2e-96 V FtsX-like permease family
HCHLGBMO_00068 4.1e-133 cysA V ABC transporter, ATP-binding protein
HCHLGBMO_00069 3.4e-23
HCHLGBMO_00071 2.5e-288 pipD E Dipeptidase
HCHLGBMO_00072 8.3e-163 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCHLGBMO_00073 0.0 smc D Required for chromosome condensation and partitioning
HCHLGBMO_00074 5.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCHLGBMO_00075 3e-307 oppA E ABC transporter substrate-binding protein
HCHLGBMO_00076 2.4e-15 oppA E ABC transporter substrate-binding protein
HCHLGBMO_00077 1.8e-116 oppA E ABC transporter substrate-binding protein
HCHLGBMO_00078 7.4e-120 oppA E ABC transporter substrate-binding protein
HCHLGBMO_00079 3.4e-129 oppC P Binding-protein-dependent transport system inner membrane component
HCHLGBMO_00080 5.7e-172 oppB P ABC transporter permease
HCHLGBMO_00081 1.3e-171 oppF P Belongs to the ABC transporter superfamily
HCHLGBMO_00082 9.6e-194 oppD P Belongs to the ABC transporter superfamily
HCHLGBMO_00083 1.8e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCHLGBMO_00084 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCHLGBMO_00085 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCHLGBMO_00086 3.4e-305 yloV S DAK2 domain fusion protein YloV
HCHLGBMO_00087 4e-57 asp S Asp23 family, cell envelope-related function
HCHLGBMO_00088 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HCHLGBMO_00089 1.1e-30
HCHLGBMO_00090 2.4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HCHLGBMO_00091 1.7e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HCHLGBMO_00092 4.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCHLGBMO_00093 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HCHLGBMO_00094 1.1e-138 stp 3.1.3.16 T phosphatase
HCHLGBMO_00095 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCHLGBMO_00096 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCHLGBMO_00097 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCHLGBMO_00098 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCHLGBMO_00099 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HCHLGBMO_00100 4.2e-77 6.3.3.2 S ASCH
HCHLGBMO_00101 3.7e-291 recN L May be involved in recombinational repair of damaged DNA
HCHLGBMO_00102 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HCHLGBMO_00103 2.4e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCHLGBMO_00104 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCHLGBMO_00105 7.6e-186 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCHLGBMO_00106 2.2e-143 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCHLGBMO_00107 2.1e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCHLGBMO_00108 3.4e-71 yqhY S Asp23 family, cell envelope-related function
HCHLGBMO_00109 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCHLGBMO_00110 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HCHLGBMO_00111 7.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HCHLGBMO_00112 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HCHLGBMO_00113 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCHLGBMO_00114 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
HCHLGBMO_00118 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HCHLGBMO_00119 2.7e-300 S Predicted membrane protein (DUF2207)
HCHLGBMO_00120 1.3e-157 cinI S Serine hydrolase (FSH1)
HCHLGBMO_00121 1.7e-205 M Glycosyl hydrolases family 25
HCHLGBMO_00123 2.9e-178 I Carboxylesterase family
HCHLGBMO_00124 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
HCHLGBMO_00125 4.1e-276 V ABC-type multidrug transport system, ATPase and permease components
HCHLGBMO_00126 2e-291 V ABC-type multidrug transport system, ATPase and permease components
HCHLGBMO_00127 4e-113 S haloacid dehalogenase-like hydrolase
HCHLGBMO_00128 2.6e-52
HCHLGBMO_00129 1.9e-37
HCHLGBMO_00130 1.1e-64 S Alpha beta hydrolase
HCHLGBMO_00131 1.1e-36 S Alpha beta hydrolase
HCHLGBMO_00132 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HCHLGBMO_00133 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HCHLGBMO_00134 7.1e-46
HCHLGBMO_00135 6.8e-148 glcU U sugar transport
HCHLGBMO_00136 2.7e-82 lctP C L-lactate permease
HCHLGBMO_00137 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HCHLGBMO_00138 2.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCHLGBMO_00139 4e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCHLGBMO_00140 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HCHLGBMO_00141 4.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCHLGBMO_00142 2.4e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCHLGBMO_00143 3.5e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCHLGBMO_00144 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCHLGBMO_00145 1.5e-102 GM NmrA-like family
HCHLGBMO_00146 2.5e-148 S Protein of unknown function (DUF805)
HCHLGBMO_00147 3.4e-135 glnQ E ABC transporter, ATP-binding protein
HCHLGBMO_00148 1.3e-290 glnP P ABC transporter permease
HCHLGBMO_00149 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HCHLGBMO_00150 5.8e-64 yeaO S Protein of unknown function, DUF488
HCHLGBMO_00151 2.1e-124 terC P Integral membrane protein TerC family
HCHLGBMO_00152 2.1e-91 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HCHLGBMO_00153 5.2e-130 cobB K SIR2 family
HCHLGBMO_00154 4.2e-86
HCHLGBMO_00155 4.6e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCHLGBMO_00156 1.3e-181 S Alpha/beta hydrolase of unknown function (DUF915)
HCHLGBMO_00157 2.3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCHLGBMO_00158 2e-140 ypuA S Protein of unknown function (DUF1002)
HCHLGBMO_00159 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HCHLGBMO_00160 3.3e-222 L Transposase
HCHLGBMO_00161 1.3e-284 lsa S ABC transporter
HCHLGBMO_00162 2.4e-44
HCHLGBMO_00163 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HCHLGBMO_00164 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HCHLGBMO_00165 9.7e-52 S Iron-sulfur cluster assembly protein
HCHLGBMO_00166 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HCHLGBMO_00167 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HCHLGBMO_00168 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HCHLGBMO_00169 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCHLGBMO_00170 3.3e-275 yjeM E Amino Acid
HCHLGBMO_00171 5.8e-83 S Fic/DOC family
HCHLGBMO_00172 9.9e-180
HCHLGBMO_00173 3.1e-93
HCHLGBMO_00174 3.2e-77
HCHLGBMO_00175 2.3e-87 S Protein of unknown function (DUF805)
HCHLGBMO_00176 5.6e-68 O OsmC-like protein
HCHLGBMO_00177 6.7e-207 EGP Major facilitator Superfamily
HCHLGBMO_00178 2.5e-215 sptS 2.7.13.3 T Histidine kinase
HCHLGBMO_00179 1.3e-65 K response regulator
HCHLGBMO_00180 6e-27 K response regulator
HCHLGBMO_00181 7.5e-109 2.7.6.5 T Region found in RelA / SpoT proteins
HCHLGBMO_00182 6.2e-271 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HCHLGBMO_00183 0.0 rafA 3.2.1.22 G alpha-galactosidase
HCHLGBMO_00184 2.8e-210 msmX P Belongs to the ABC transporter superfamily
HCHLGBMO_00185 2e-152 msmG P Binding-protein-dependent transport system inner membrane component
HCHLGBMO_00186 4.8e-157 msmF P Binding-protein-dependent transport system inner membrane component
HCHLGBMO_00187 2.3e-237 msmE G Bacterial extracellular solute-binding protein
HCHLGBMO_00188 1.6e-158 scrR K Periplasmic binding protein domain
HCHLGBMO_00189 5.5e-36
HCHLGBMO_00190 2.2e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HCHLGBMO_00191 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HCHLGBMO_00192 2.1e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCHLGBMO_00193 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HCHLGBMO_00194 5.3e-138 lacS G Transporter
HCHLGBMO_00195 1.1e-87 lacS G Transporter
HCHLGBMO_00196 4.1e-67 lacS G Transporter
HCHLGBMO_00197 3.2e-165 lacR K Transcriptional regulator
HCHLGBMO_00198 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HCHLGBMO_00199 4.6e-57 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HCHLGBMO_00200 8.3e-80 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HCHLGBMO_00201 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HCHLGBMO_00202 6.4e-162 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HCHLGBMO_00203 2e-106 K Transcriptional regulator, AbiEi antitoxin
HCHLGBMO_00204 1.2e-188 K Periplasmic binding protein-like domain
HCHLGBMO_00205 9.3e-74 coaA 2.7.1.33 F Pantothenic acid kinase
HCHLGBMO_00207 7.1e-75 S ECF transporter, substrate-specific component
HCHLGBMO_00208 1.5e-54 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCHLGBMO_00209 3.7e-144 gltC_1 3.1.3.48 K LysR substrate binding domain
HCHLGBMO_00210 1.1e-149 2.8.3.1 I Coenzyme A transferase
HCHLGBMO_00211 1.6e-82 2.8.3.1 I Coenzyme A transferase
HCHLGBMO_00212 5.1e-106 fabK 1.3.1.9 S Nitronate monooxygenase
HCHLGBMO_00213 1.4e-223 L Transposase
HCHLGBMO_00214 3.6e-88 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCHLGBMO_00215 7.7e-10 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCHLGBMO_00216 2.9e-109 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HCHLGBMO_00217 1.7e-36 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HCHLGBMO_00218 1.1e-59 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HCHLGBMO_00219 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCHLGBMO_00220 1.9e-121 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCHLGBMO_00221 2.3e-56 G Xylose isomerase domain protein TIM barrel
HCHLGBMO_00222 8.4e-90 nanK GK ROK family
HCHLGBMO_00223 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HCHLGBMO_00224 3.7e-66 K Helix-turn-helix domain, rpiR family
HCHLGBMO_00225 7.1e-263 E ABC transporter, substratebinding protein
HCHLGBMO_00226 9.1e-10 K peptidyl-tyrosine sulfation
HCHLGBMO_00228 1.2e-128 S interspecies interaction between organisms
HCHLGBMO_00229 2.7e-34
HCHLGBMO_00232 1.9e-21
HCHLGBMO_00233 1.7e-147
HCHLGBMO_00234 6.7e-170
HCHLGBMO_00235 2e-263 glnA 6.3.1.2 E glutamine synthetase
HCHLGBMO_00236 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
HCHLGBMO_00237 1.5e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCHLGBMO_00238 1.5e-65 yqhL P Rhodanese-like protein
HCHLGBMO_00239 4.8e-35 yqgQ S Bacterial protein of unknown function (DUF910)
HCHLGBMO_00240 4e-119 gluP 3.4.21.105 S Rhomboid family
HCHLGBMO_00241 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCHLGBMO_00242 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HCHLGBMO_00243 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HCHLGBMO_00244 0.0 S membrane
HCHLGBMO_00245 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HCHLGBMO_00246 1.3e-38 S RelB antitoxin
HCHLGBMO_00247 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HCHLGBMO_00248 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCHLGBMO_00249 2e-138 fhuC 3.6.3.34 HP abc transporter atp-binding protein
HCHLGBMO_00250 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCHLGBMO_00251 8.7e-159 isdE P Periplasmic binding protein
HCHLGBMO_00252 6.3e-123 M Iron Transport-associated domain
HCHLGBMO_00253 3e-09 isdH M Iron Transport-associated domain
HCHLGBMO_00254 2.2e-89
HCHLGBMO_00255 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
HCHLGBMO_00256 8.3e-122 S Alpha/beta hydrolase family
HCHLGBMO_00257 1e-88 K Helix-turn-helix domain
HCHLGBMO_00258 1.4e-26 L Transposase
HCHLGBMO_00259 1.1e-112 S SLAP domain
HCHLGBMO_00260 2.6e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HCHLGBMO_00261 5.7e-46 S An automated process has identified a potential problem with this gene model
HCHLGBMO_00262 3e-137 S Protein of unknown function (DUF3100)
HCHLGBMO_00263 1.4e-245 3.5.1.47 S Peptidase dimerisation domain
HCHLGBMO_00264 1.1e-231 Q Imidazolonepropionase and related amidohydrolases
HCHLGBMO_00265 0.0 oppA E ABC transporter
HCHLGBMO_00266 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
HCHLGBMO_00267 0.0 mco Q Multicopper oxidase
HCHLGBMO_00268 1.9e-25
HCHLGBMO_00269 3.8e-136 metQ1 P Belongs to the nlpA lipoprotein family
HCHLGBMO_00270 3.7e-168 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HCHLGBMO_00271 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCHLGBMO_00272 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCHLGBMO_00273 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCHLGBMO_00274 6.2e-157 cjaA ET ABC transporter substrate-binding protein
HCHLGBMO_00275 3.3e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCHLGBMO_00276 5.3e-116 P ABC transporter permease
HCHLGBMO_00277 2.7e-107 papP P ABC transporter, permease protein
HCHLGBMO_00279 4.5e-58 yodB K Transcriptional regulator, HxlR family
HCHLGBMO_00280 7.7e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCHLGBMO_00281 2.4e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HCHLGBMO_00282 2.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCHLGBMO_00283 1.3e-82 S Aminoacyl-tRNA editing domain
HCHLGBMO_00284 1e-184 S SLAP domain
HCHLGBMO_00285 6.6e-32 S SLAP domain
HCHLGBMO_00286 9.2e-100 S CAAX protease self-immunity
HCHLGBMO_00287 1e-12
HCHLGBMO_00288 1.3e-277 arlS 2.7.13.3 T Histidine kinase
HCHLGBMO_00289 1.2e-126 K response regulator
HCHLGBMO_00290 4.7e-97 yceD S Uncharacterized ACR, COG1399
HCHLGBMO_00291 4.6e-216 ylbM S Belongs to the UPF0348 family
HCHLGBMO_00292 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCHLGBMO_00293 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HCHLGBMO_00294 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCHLGBMO_00295 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
HCHLGBMO_00296 1.6e-83 yqeG S HAD phosphatase, family IIIA
HCHLGBMO_00297 8.6e-199 tnpB L Putative transposase DNA-binding domain
HCHLGBMO_00298 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HCHLGBMO_00299 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCHLGBMO_00300 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HCHLGBMO_00301 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCHLGBMO_00302 9e-98 rihB 3.2.2.1 F Nucleoside
HCHLGBMO_00303 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCHLGBMO_00304 1.3e-168 dnaI L Primosomal protein DnaI
HCHLGBMO_00305 8.6e-251 dnaB L Replication initiation and membrane attachment
HCHLGBMO_00306 3.9e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCHLGBMO_00307 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCHLGBMO_00308 9.4e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCHLGBMO_00309 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCHLGBMO_00310 6e-20
HCHLGBMO_00311 1.9e-199 purD 6.3.4.13 F Belongs to the GARS family
HCHLGBMO_00312 9.1e-140 qmcA O prohibitin homologues
HCHLGBMO_00313 2.4e-50 L RelB antitoxin
HCHLGBMO_00314 1.6e-18
HCHLGBMO_00315 2.7e-193 S Bacteriocin helveticin-J
HCHLGBMO_00316 1.2e-157 M Peptidase family M1 domain
HCHLGBMO_00317 3.3e-37 L Resolvase, N-terminal
HCHLGBMO_00318 1.7e-84 L Putative transposase DNA-binding domain
HCHLGBMO_00319 7.4e-74 L Putative transposase DNA-binding domain
HCHLGBMO_00320 8.4e-171 S SLAP domain
HCHLGBMO_00321 1.6e-233 mepA V MATE efflux family protein
HCHLGBMO_00322 8.8e-248 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HCHLGBMO_00323 3.7e-185
HCHLGBMO_00324 2.4e-121 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCHLGBMO_00325 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HCHLGBMO_00326 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCHLGBMO_00327 2.9e-221 ecsB U ABC transporter
HCHLGBMO_00328 1.7e-134 ecsA V ABC transporter, ATP-binding protein
HCHLGBMO_00329 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
HCHLGBMO_00330 3.9e-25
HCHLGBMO_00331 1.5e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCHLGBMO_00332 1.5e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HCHLGBMO_00333 3.1e-265
HCHLGBMO_00334 2.4e-51 S Domain of unknown function DUF1829
HCHLGBMO_00335 2.3e-17
HCHLGBMO_00337 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCHLGBMO_00338 0.0 L AAA domain
HCHLGBMO_00339 1.5e-230 yhaO L Ser Thr phosphatase family protein
HCHLGBMO_00340 7.2e-56 yheA S Belongs to the UPF0342 family
HCHLGBMO_00341 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HCHLGBMO_00342 6.5e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCHLGBMO_00343 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HCHLGBMO_00344 8.9e-10 G Phosphoglycerate mutase family
HCHLGBMO_00345 2.9e-78 G Phosphoglycerate mutase family
HCHLGBMO_00346 1.6e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCHLGBMO_00347 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HCHLGBMO_00348 1.8e-193 I transferase activity, transferring acyl groups other than amino-acyl groups
HCHLGBMO_00349 5.6e-179 S PFAM Archaeal ATPase
HCHLGBMO_00350 4.7e-92 yniG EGP Major facilitator Superfamily
HCHLGBMO_00351 9.2e-237 L transposase, IS605 OrfB family
HCHLGBMO_00352 2.9e-73 yniG EGP Major facilitator Superfamily
HCHLGBMO_00353 3.5e-29
HCHLGBMO_00355 1.3e-197 EGP Major Facilitator Superfamily
HCHLGBMO_00356 2.4e-88 noxC 1.5.1.39 C coenzyme F420-1:gamma-L-glutamate ligase activity
HCHLGBMO_00357 1.1e-22 noxC 1.5.1.39 C coenzyme F420-1:gamma-L-glutamate ligase activity
HCHLGBMO_00358 4.3e-76 menA 2.5.1.74 H UbiA prenyltransferase family
HCHLGBMO_00359 7.7e-26
HCHLGBMO_00360 5.1e-91 S PFAM Archaeal ATPase
HCHLGBMO_00361 3e-90 S PFAM Archaeal ATPase
HCHLGBMO_00362 6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HCHLGBMO_00363 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HCHLGBMO_00364 7.9e-99 M ErfK YbiS YcfS YnhG
HCHLGBMO_00365 6.4e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCHLGBMO_00366 1.6e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HCHLGBMO_00368 4.3e-47 pspC KT PspC domain
HCHLGBMO_00369 6.8e-298 ytgP S Polysaccharide biosynthesis protein
HCHLGBMO_00370 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCHLGBMO_00371 6.4e-122 3.6.1.27 I Acid phosphatase homologues
HCHLGBMO_00372 2.6e-169 K LysR substrate binding domain
HCHLGBMO_00373 1.6e-85 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HCHLGBMO_00374 1.6e-43 1.3.5.4 C FAD binding domain
HCHLGBMO_00375 1.2e-230 ndh 1.6.99.3 C NADH dehydrogenase
HCHLGBMO_00376 1.8e-159 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HCHLGBMO_00377 6.1e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCHLGBMO_00378 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HCHLGBMO_00379 2.4e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HCHLGBMO_00380 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HCHLGBMO_00381 2.5e-173 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HCHLGBMO_00382 6.4e-243 cydA 1.10.3.14 C ubiquinol oxidase
HCHLGBMO_00383 7e-23 cydA 1.10.3.14 C ubiquinol oxidase
HCHLGBMO_00384 4.5e-144 ybbH_2 K rpiR family
HCHLGBMO_00385 3.1e-187 S Bacterial protein of unknown function (DUF871)
HCHLGBMO_00386 1.4e-183 yfeW 3.4.16.4 V Beta-lactamase
HCHLGBMO_00387 3.1e-151 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HCHLGBMO_00388 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCHLGBMO_00389 2.4e-246 qacA EGP Major facilitator Superfamily
HCHLGBMO_00390 8.7e-218 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCHLGBMO_00393 1.8e-151 psaA P Belongs to the bacterial solute-binding protein 9 family
HCHLGBMO_00394 6.1e-227 L COG3547 Transposase and inactivated derivatives
HCHLGBMO_00395 6e-125 UW LPXTG-motif cell wall anchor domain protein
HCHLGBMO_00396 4.6e-195 UW LPXTG-motif cell wall anchor domain protein
HCHLGBMO_00397 9.6e-45 UW LPXTG-motif cell wall anchor domain protein
HCHLGBMO_00398 7.8e-26 UW LPXTG-motif cell wall anchor domain protein
HCHLGBMO_00399 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCHLGBMO_00400 1.7e-99 J Acetyltransferase (GNAT) domain
HCHLGBMO_00401 1.7e-108 yjbF S SNARE associated Golgi protein
HCHLGBMO_00402 1.3e-150 I alpha/beta hydrolase fold
HCHLGBMO_00403 1.5e-155 hipB K Helix-turn-helix
HCHLGBMO_00404 2.6e-83 F Nucleoside 2-deoxyribosyltransferase
HCHLGBMO_00405 6.8e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HCHLGBMO_00406 9.4e-147
HCHLGBMO_00407 0.0 ydgH S MMPL family
HCHLGBMO_00408 2.3e-99 yobS K Bacterial regulatory proteins, tetR family
HCHLGBMO_00409 7.4e-148 3.5.2.6 V Beta-lactamase enzyme family
HCHLGBMO_00410 4.4e-153 corA P CorA-like Mg2+ transporter protein
HCHLGBMO_00411 1.5e-239 G Bacterial extracellular solute-binding protein
HCHLGBMO_00412 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HCHLGBMO_00413 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
HCHLGBMO_00414 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
HCHLGBMO_00415 9.3e-203 malK P ATPases associated with a variety of cellular activities
HCHLGBMO_00416 1.6e-282 pipD E Dipeptidase
HCHLGBMO_00417 1.9e-158 endA F DNA RNA non-specific endonuclease
HCHLGBMO_00418 1e-181 dnaQ 2.7.7.7 L EXOIII
HCHLGBMO_00419 2.4e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HCHLGBMO_00420 3e-116 yviA S Protein of unknown function (DUF421)
HCHLGBMO_00421 1.1e-56 S Protein of unknown function (DUF3290)
HCHLGBMO_00423 3.8e-139 pnuC H nicotinamide mononucleotide transporter
HCHLGBMO_00424 4e-08
HCHLGBMO_00425 6.6e-56
HCHLGBMO_00426 2.7e-57
HCHLGBMO_00427 1.6e-11
HCHLGBMO_00428 1.5e-124 S PAS domain
HCHLGBMO_00429 8.2e-182 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCHLGBMO_00430 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
HCHLGBMO_00431 3.1e-134
HCHLGBMO_00432 1.3e-258 glnPH2 P ABC transporter permease
HCHLGBMO_00433 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCHLGBMO_00434 6.4e-224 S Cysteine-rich secretory protein family
HCHLGBMO_00435 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HCHLGBMO_00436 1.4e-112
HCHLGBMO_00437 2.2e-202 yibE S overlaps another CDS with the same product name
HCHLGBMO_00438 1.7e-129 yibF S overlaps another CDS with the same product name
HCHLGBMO_00439 6.7e-145 I alpha/beta hydrolase fold
HCHLGBMO_00440 0.0 G Belongs to the glycosyl hydrolase 31 family
HCHLGBMO_00441 1e-215 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCHLGBMO_00442 1.2e-08
HCHLGBMO_00443 2.9e-277 V ABC transporter transmembrane region
HCHLGBMO_00444 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HCHLGBMO_00445 3.1e-130 T Transcriptional regulatory protein, C terminal
HCHLGBMO_00446 5.2e-187 T GHKL domain
HCHLGBMO_00447 5.8e-76 S Peptidase propeptide and YPEB domain
HCHLGBMO_00448 2.5e-72 S Peptidase propeptide and YPEB domain
HCHLGBMO_00449 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HCHLGBMO_00450 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
HCHLGBMO_00451 7e-68 V ABC transporter transmembrane region
HCHLGBMO_00452 9e-161 V ABC transporter transmembrane region
HCHLGBMO_00453 2.3e-309 oppA3 E ABC transporter, substratebinding protein
HCHLGBMO_00454 8.8e-58 S Peptidase propeptide and YPEB domain
HCHLGBMO_00455 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCHLGBMO_00456 7.4e-169 coaA 2.7.1.33 F Pantothenic acid kinase
HCHLGBMO_00457 7.1e-98 E GDSL-like Lipase/Acylhydrolase
HCHLGBMO_00458 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
HCHLGBMO_00459 1.6e-143 aatB ET ABC transporter substrate-binding protein
HCHLGBMO_00460 1e-105 glnQ 3.6.3.21 E ABC transporter
HCHLGBMO_00461 1.5e-107 glnP P ABC transporter permease
HCHLGBMO_00462 0.0 helD 3.6.4.12 L DNA helicase
HCHLGBMO_00463 2.3e-116 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HCHLGBMO_00464 1.4e-126 pgm3 G Phosphoglycerate mutase family
HCHLGBMO_00465 1.2e-241 S response to antibiotic
HCHLGBMO_00466 3.2e-124
HCHLGBMO_00467 0.0 3.6.3.8 P P-type ATPase
HCHLGBMO_00468 4.3e-65 2.7.1.191 G PTS system fructose IIA component
HCHLGBMO_00469 4.4e-43
HCHLGBMO_00470 5.9e-09
HCHLGBMO_00471 5.2e-104
HCHLGBMO_00474 1.7e-29 S Predicted membrane protein (DUF2335)
HCHLGBMO_00476 1.5e-215 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCHLGBMO_00477 3.5e-175 S Cysteine-rich secretory protein family
HCHLGBMO_00478 3.5e-41
HCHLGBMO_00479 2.6e-118 M NlpC/P60 family
HCHLGBMO_00480 1.4e-136 M NlpC P60 family protein
HCHLGBMO_00481 2e-89 M NlpC/P60 family
HCHLGBMO_00482 7.7e-89 gmk2 2.7.4.8 F Guanylate kinase homologues.
HCHLGBMO_00483 3.9e-42
HCHLGBMO_00484 1.1e-278 S O-antigen ligase like membrane protein
HCHLGBMO_00485 3.3e-112
HCHLGBMO_00486 1.1e-222 tnpB L Putative transposase DNA-binding domain
HCHLGBMO_00487 2.6e-29 nrdI F NrdI Flavodoxin like
HCHLGBMO_00488 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCHLGBMO_00489 2.5e-68
HCHLGBMO_00490 9.1e-112 yvpB S Peptidase_C39 like family
HCHLGBMO_00491 1.1e-75 S Threonine/Serine exporter, ThrE
HCHLGBMO_00492 2.4e-136 thrE S Putative threonine/serine exporter
HCHLGBMO_00493 8.9e-292 S ABC transporter
HCHLGBMO_00494 4.1e-57
HCHLGBMO_00495 1.2e-97 rimL J Acetyltransferase (GNAT) domain
HCHLGBMO_00496 5.6e-19
HCHLGBMO_00497 8.2e-61
HCHLGBMO_00498 3.5e-123 S Protein of unknown function (DUF554)
HCHLGBMO_00499 6.4e-208 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HCHLGBMO_00500 0.0 pepF E oligoendopeptidase F
HCHLGBMO_00501 7.4e-40 S Enterocin A Immunity
HCHLGBMO_00502 2.2e-85 S CAAX amino terminal protease
HCHLGBMO_00506 2e-25 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_00507 1.2e-11
HCHLGBMO_00509 5.4e-214 2.1.1.14 E methionine synthase, vitamin-B12 independent
HCHLGBMO_00510 6.1e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCHLGBMO_00511 1.1e-08 S CAAX amino terminal protease
HCHLGBMO_00512 6.5e-85 L Transposase
HCHLGBMO_00513 3e-72 L Transposase
HCHLGBMO_00516 1.7e-28 mloB K Putative ATP-dependent DNA helicase recG C-terminal
HCHLGBMO_00517 3.5e-248 lctP C L-lactate permease
HCHLGBMO_00518 5e-129 znuB U ABC 3 transport family
HCHLGBMO_00519 1.6e-117 fhuC P ABC transporter
HCHLGBMO_00520 1.4e-148 psaA P Belongs to the bacterial solute-binding protein 9 family
HCHLGBMO_00521 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCHLGBMO_00522 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HCHLGBMO_00523 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HCHLGBMO_00524 1.8e-136 fruR K DeoR C terminal sensor domain
HCHLGBMO_00525 1.8e-218 natB CP ABC-2 family transporter protein
HCHLGBMO_00526 1.1e-164 natA S ABC transporter, ATP-binding protein
HCHLGBMO_00527 1.7e-67
HCHLGBMO_00528 2e-23
HCHLGBMO_00529 8.2e-31 yozG K Transcriptional regulator
HCHLGBMO_00530 3.7e-83
HCHLGBMO_00531 3e-21
HCHLGBMO_00535 2.2e-129 blpT
HCHLGBMO_00536 1.4e-107 M Transport protein ComB
HCHLGBMO_00537 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HCHLGBMO_00538 1.2e-127 K LytTr DNA-binding domain
HCHLGBMO_00539 4.4e-138 2.7.13.3 T GHKL domain
HCHLGBMO_00540 1.2e-16
HCHLGBMO_00541 2.1e-255 S Archaea bacterial proteins of unknown function
HCHLGBMO_00542 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HCHLGBMO_00543 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HCHLGBMO_00544 1e-24
HCHLGBMO_00545 9.5e-26
HCHLGBMO_00546 2.5e-33
HCHLGBMO_00547 1.4e-53 S Enterocin A Immunity
HCHLGBMO_00548 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HCHLGBMO_00549 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCHLGBMO_00550 1.9e-206 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HCHLGBMO_00551 9.6e-121 K response regulator
HCHLGBMO_00552 0.0 V ABC transporter
HCHLGBMO_00553 4.2e-144 V ABC transporter, ATP-binding protein
HCHLGBMO_00554 1.2e-145 V ABC transporter, ATP-binding protein
HCHLGBMO_00555 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
HCHLGBMO_00556 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCHLGBMO_00557 2.8e-44 yyzM S Bacterial protein of unknown function (DUF951)
HCHLGBMO_00558 1.5e-153 spo0J K Belongs to the ParB family
HCHLGBMO_00559 3.4e-138 soj D Sporulation initiation inhibitor
HCHLGBMO_00560 5e-148 noc K Belongs to the ParB family
HCHLGBMO_00561 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HCHLGBMO_00562 3e-53 cvpA S Colicin V production protein
HCHLGBMO_00564 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCHLGBMO_00565 6e-151 3.1.3.48 T Tyrosine phosphatase family
HCHLGBMO_00566 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
HCHLGBMO_00567 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HCHLGBMO_00568 3.7e-111 K WHG domain
HCHLGBMO_00569 5.7e-32
HCHLGBMO_00570 3.4e-274 pipD E Dipeptidase
HCHLGBMO_00571 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HCHLGBMO_00572 3.3e-176 hrtB V ABC transporter permease
HCHLGBMO_00573 1e-90 ygfC K Bacterial regulatory proteins, tetR family
HCHLGBMO_00574 3.5e-111 G phosphoglycerate mutase
HCHLGBMO_00575 7e-141 aroD S Alpha/beta hydrolase family
HCHLGBMO_00576 2.2e-142 S Belongs to the UPF0246 family
HCHLGBMO_00577 2.6e-120
HCHLGBMO_00578 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
HCHLGBMO_00579 5.2e-08
HCHLGBMO_00580 3e-89 ntd 2.4.2.6 F Nucleoside
HCHLGBMO_00581 1.7e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCHLGBMO_00582 3.4e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HCHLGBMO_00583 3e-84 uspA T universal stress protein
HCHLGBMO_00585 1.5e-161 phnD P Phosphonate ABC transporter
HCHLGBMO_00586 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HCHLGBMO_00587 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HCHLGBMO_00588 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HCHLGBMO_00589 3.3e-106 tag 3.2.2.20 L glycosylase
HCHLGBMO_00590 3.9e-84
HCHLGBMO_00591 1.7e-273 S Calcineurin-like phosphoesterase
HCHLGBMO_00592 0.0 asnB 6.3.5.4 E Asparagine synthase
HCHLGBMO_00593 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
HCHLGBMO_00594 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HCHLGBMO_00595 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCHLGBMO_00596 2.1e-103 S Iron-sulfur cluster assembly protein
HCHLGBMO_00597 1.5e-230 XK27_04775 S PAS domain
HCHLGBMO_00598 2.3e-210 yttB EGP Major facilitator Superfamily
HCHLGBMO_00599 0.0 pepO 3.4.24.71 O Peptidase family M13
HCHLGBMO_00600 0.0 kup P Transport of potassium into the cell
HCHLGBMO_00601 7.3e-74
HCHLGBMO_00602 2.1e-45 S PFAM Archaeal ATPase
HCHLGBMO_00604 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HCHLGBMO_00605 5.9e-45
HCHLGBMO_00606 1.2e-190 S Putative peptidoglycan binding domain
HCHLGBMO_00607 4e-16
HCHLGBMO_00608 7.9e-92 liaI S membrane
HCHLGBMO_00609 1.7e-70 XK27_02470 K LytTr DNA-binding domain
HCHLGBMO_00610 3.5e-236 L transposase, IS605 OrfB family
HCHLGBMO_00611 2.1e-28 S Peptidase propeptide and YPEB domain
HCHLGBMO_00612 4.5e-60 ypaA S Protein of unknown function (DUF1304)
HCHLGBMO_00613 5.3e-249 dtpT U amino acid peptide transporter
HCHLGBMO_00614 2.4e-35 L Transposase DDE domain
HCHLGBMO_00615 1.1e-259 L Transposase
HCHLGBMO_00616 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCHLGBMO_00617 7.9e-73 nrdI F NrdI Flavodoxin like
HCHLGBMO_00618 1.4e-192 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCHLGBMO_00619 2.9e-285 phoR 2.7.13.3 T Histidine kinase
HCHLGBMO_00620 8.9e-119 T Transcriptional regulatory protein, C terminal
HCHLGBMO_00621 1.3e-103 phoU P Plays a role in the regulation of phosphate uptake
HCHLGBMO_00622 1.6e-137 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCHLGBMO_00623 4.6e-152 pstA P Phosphate transport system permease protein PstA
HCHLGBMO_00624 4.6e-155 pstC P probably responsible for the translocation of the substrate across the membrane
HCHLGBMO_00625 9.4e-145 pstS P Phosphate
HCHLGBMO_00626 3.2e-26 xerC L Phage integrase, N-terminal SAM-like domain
HCHLGBMO_00627 1.8e-82 yveB 2.7.4.29 I PAP2 superfamily
HCHLGBMO_00628 0.0 pepN 3.4.11.2 E aminopeptidase
HCHLGBMO_00629 2.8e-47 lysM M LysM domain
HCHLGBMO_00630 7.4e-175
HCHLGBMO_00631 3.3e-99 mdtG EGP Major facilitator Superfamily
HCHLGBMO_00632 1.7e-100 mdtG EGP Major facilitator Superfamily
HCHLGBMO_00633 6.7e-88 ymdB S Macro domain protein
HCHLGBMO_00635 6.7e-09
HCHLGBMO_00636 1.6e-28
HCHLGBMO_00639 1.5e-59 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_00640 3.3e-147 malG P ABC transporter permease
HCHLGBMO_00641 2.6e-250 malF P Binding-protein-dependent transport system inner membrane component
HCHLGBMO_00642 2.3e-213 malE G Bacterial extracellular solute-binding protein
HCHLGBMO_00643 6.8e-209 msmX P Belongs to the ABC transporter superfamily
HCHLGBMO_00644 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HCHLGBMO_00645 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HCHLGBMO_00646 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HCHLGBMO_00647 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HCHLGBMO_00648 9.8e-49 S PAS domain
HCHLGBMO_00649 2e-203 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCHLGBMO_00650 3.1e-178 yvdE K helix_turn _helix lactose operon repressor
HCHLGBMO_00651 7e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
HCHLGBMO_00652 3e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCHLGBMO_00653 2.8e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HCHLGBMO_00654 2.3e-18
HCHLGBMO_00655 4e-137 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_00657 2.3e-121 V Abi-like protein
HCHLGBMO_00658 4e-75 S Uncharacterised protein family (UPF0236)
HCHLGBMO_00659 6.8e-186 G Transmembrane secretion effector
HCHLGBMO_00660 1.2e-201 V ABC transporter transmembrane region
HCHLGBMO_00661 6.5e-64 L RelB antitoxin
HCHLGBMO_00662 2.1e-131 cobQ S glutamine amidotransferase
HCHLGBMO_00663 1.1e-81 M NlpC/P60 family
HCHLGBMO_00665 2.7e-141 L An automated process has identified a potential problem with this gene model
HCHLGBMO_00666 2.3e-36
HCHLGBMO_00667 2.4e-130 EG EamA-like transporter family
HCHLGBMO_00668 5.9e-166 EG EamA-like transporter family
HCHLGBMO_00669 7.3e-83 yicL EG EamA-like transporter family
HCHLGBMO_00670 3.5e-83
HCHLGBMO_00671 1.2e-109
HCHLGBMO_00672 5.4e-15 XK27_05540 S DUF218 domain
HCHLGBMO_00673 1e-142 XK27_05540 S DUF218 domain
HCHLGBMO_00674 4.9e-265 yheS_2 S ATPases associated with a variety of cellular activities
HCHLGBMO_00675 7.2e-86
HCHLGBMO_00676 3.9e-57
HCHLGBMO_00677 4.7e-25 S Protein conserved in bacteria
HCHLGBMO_00678 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
HCHLGBMO_00680 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCHLGBMO_00681 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCHLGBMO_00682 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCHLGBMO_00685 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HCHLGBMO_00686 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
HCHLGBMO_00687 1.8e-230 steT_1 E amino acid
HCHLGBMO_00688 2.2e-139 puuD S peptidase C26
HCHLGBMO_00690 2.4e-172 V HNH endonuclease
HCHLGBMO_00691 6.4e-135 S PFAM Archaeal ATPase
HCHLGBMO_00692 6e-247 yifK E Amino acid permease
HCHLGBMO_00693 9.7e-234 cycA E Amino acid permease
HCHLGBMO_00694 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HCHLGBMO_00695 0.0 clpE O AAA domain (Cdc48 subfamily)
HCHLGBMO_00696 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
HCHLGBMO_00697 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCHLGBMO_00698 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
HCHLGBMO_00699 0.0 XK27_06780 V ABC transporter permease
HCHLGBMO_00700 1.9e-36
HCHLGBMO_00701 7.9e-291 ytgP S Polysaccharide biosynthesis protein
HCHLGBMO_00702 2.7e-137 lysA2 M Glycosyl hydrolases family 25
HCHLGBMO_00703 2.3e-133 S Protein of unknown function (DUF975)
HCHLGBMO_00704 7.6e-177 pbpX2 V Beta-lactamase
HCHLGBMO_00705 1.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HCHLGBMO_00706 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCHLGBMO_00707 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
HCHLGBMO_00708 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCHLGBMO_00709 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
HCHLGBMO_00710 4.1e-44
HCHLGBMO_00711 1e-207 ywhK S Membrane
HCHLGBMO_00712 1.5e-80 ykuL S (CBS) domain
HCHLGBMO_00713 0.0 cadA P P-type ATPase
HCHLGBMO_00714 2.8e-205 napA P Sodium/hydrogen exchanger family
HCHLGBMO_00715 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HCHLGBMO_00716 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HCHLGBMO_00717 4.1e-276 V ABC transporter transmembrane region
HCHLGBMO_00718 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
HCHLGBMO_00719 5.4e-51
HCHLGBMO_00720 4.2e-154 EGP Major facilitator Superfamily
HCHLGBMO_00721 2.5e-110 ropB K Transcriptional regulator
HCHLGBMO_00722 9.1e-121 S CAAX protease self-immunity
HCHLGBMO_00723 3.7e-191 S DUF218 domain
HCHLGBMO_00724 0.0 macB_3 V ABC transporter, ATP-binding protein
HCHLGBMO_00725 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HCHLGBMO_00726 2.8e-100 S ECF transporter, substrate-specific component
HCHLGBMO_00727 2.3e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
HCHLGBMO_00728 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
HCHLGBMO_00729 3.4e-283 xylG 3.6.3.17 S ABC transporter
HCHLGBMO_00730 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
HCHLGBMO_00731 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
HCHLGBMO_00732 1.1e-68 yeaE S Aldo/keto reductase family
HCHLGBMO_00733 1.8e-77 yeaE S Aldo/keto reductase family
HCHLGBMO_00734 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCHLGBMO_00735 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HCHLGBMO_00736 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HCHLGBMO_00737 6.2e-33
HCHLGBMO_00738 7e-139 cof S haloacid dehalogenase-like hydrolase
HCHLGBMO_00739 2.2e-230 pbuG S permease
HCHLGBMO_00740 2.1e-76 S ABC-2 family transporter protein
HCHLGBMO_00741 4.7e-60 S ABC-2 family transporter protein
HCHLGBMO_00742 1.7e-93 V ABC transporter, ATP-binding protein
HCHLGBMO_00743 8.9e-35
HCHLGBMO_00744 2.5e-119 K helix_turn_helix, mercury resistance
HCHLGBMO_00745 2.6e-86 pbuG S permease
HCHLGBMO_00746 1.8e-128 pbuG S permease
HCHLGBMO_00747 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
HCHLGBMO_00748 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
HCHLGBMO_00749 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HCHLGBMO_00750 1.3e-94 K Transcriptional regulator
HCHLGBMO_00751 6.1e-61 K Transcriptional regulator
HCHLGBMO_00752 2e-225 S cog cog1373
HCHLGBMO_00753 9.7e-146 S haloacid dehalogenase-like hydrolase
HCHLGBMO_00754 2.5e-226 pbuG S permease
HCHLGBMO_00755 6.3e-221 L Transposase
HCHLGBMO_00756 1.4e-37 S Putative adhesin
HCHLGBMO_00758 5.5e-30
HCHLGBMO_00759 4.3e-40 S Protein of unknown function (DUF2922)
HCHLGBMO_00760 8.5e-105 S SLAP domain
HCHLGBMO_00761 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HCHLGBMO_00763 4.3e-145 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HCHLGBMO_00764 3.7e-261 V ABC transporter transmembrane region
HCHLGBMO_00765 1.1e-139
HCHLGBMO_00766 1.8e-31
HCHLGBMO_00769 8.1e-37
HCHLGBMO_00770 9.2e-57 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HCHLGBMO_00771 1.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HCHLGBMO_00772 0.0 copA 3.6.3.54 P P-type ATPase
HCHLGBMO_00773 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HCHLGBMO_00774 1.2e-105
HCHLGBMO_00775 7e-248 EGP Sugar (and other) transporter
HCHLGBMO_00776 1.2e-18
HCHLGBMO_00777 2.8e-210
HCHLGBMO_00778 3.5e-136 S SLAP domain
HCHLGBMO_00779 1.3e-117 S SLAP domain
HCHLGBMO_00780 2.6e-87 S Bacteriocin helveticin-J
HCHLGBMO_00781 3.1e-12 S Bacteriocin helveticin-J
HCHLGBMO_00782 5.7e-44
HCHLGBMO_00783 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_00784 3.6e-33 E Zn peptidase
HCHLGBMO_00785 1.1e-286 clcA P chloride
HCHLGBMO_00786 6e-45 L Transposase DDE domain
HCHLGBMO_00787 3.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCHLGBMO_00788 1.6e-31
HCHLGBMO_00789 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCHLGBMO_00790 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCHLGBMO_00791 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCHLGBMO_00792 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCHLGBMO_00793 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCHLGBMO_00794 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HCHLGBMO_00795 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCHLGBMO_00796 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HCHLGBMO_00797 1.5e-102 srtA 3.4.22.70 M sortase family
HCHLGBMO_00798 2.5e-35 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HCHLGBMO_00799 5.9e-24
HCHLGBMO_00800 2e-68 M Glycosyl hydrolases family 25
HCHLGBMO_00801 5.4e-92 M Glycosyl hydrolases family 25
HCHLGBMO_00802 5e-29
HCHLGBMO_00803 7.9e-19
HCHLGBMO_00805 1.1e-07
HCHLGBMO_00806 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
HCHLGBMO_00807 7.1e-38
HCHLGBMO_00813 1.6e-36
HCHLGBMO_00814 1.1e-08
HCHLGBMO_00815 1.7e-125 Z012_12235 S Baseplate J-like protein
HCHLGBMO_00816 9.5e-33
HCHLGBMO_00817 1.2e-48
HCHLGBMO_00818 5.7e-104
HCHLGBMO_00819 2.1e-46
HCHLGBMO_00820 1.2e-58 M LysM domain
HCHLGBMO_00821 0.0 3.4.14.13 M Phage tail tape measure protein TP901
HCHLGBMO_00823 9e-27
HCHLGBMO_00824 4e-56
HCHLGBMO_00825 9.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
HCHLGBMO_00826 8e-57
HCHLGBMO_00827 2.9e-45
HCHLGBMO_00828 1.5e-75
HCHLGBMO_00829 2.1e-30 S Protein of unknown function (DUF4054)
HCHLGBMO_00830 3.5e-142 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
HCHLGBMO_00831 1.6e-58
HCHLGBMO_00832 3.9e-87 S Uncharacterized protein conserved in bacteria (DUF2213)
HCHLGBMO_00833 1.1e-07 S Lysin motif
HCHLGBMO_00834 1e-97 S Phage Mu protein F like protein
HCHLGBMO_00835 7e-142 S Protein of unknown function (DUF1073)
HCHLGBMO_00836 1.8e-230 S Terminase-like family
HCHLGBMO_00837 1.5e-28 L Terminase small subunit
HCHLGBMO_00838 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
HCHLGBMO_00839 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
HCHLGBMO_00846 2.1e-14
HCHLGBMO_00847 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
HCHLGBMO_00853 9.3e-51 dnaC L IstB-like ATP binding protein
HCHLGBMO_00854 2.7e-34 S Conserved phage C-terminus (Phg_2220_C)
HCHLGBMO_00855 6.5e-57 S Protein of unknown function (DUF1071)
HCHLGBMO_00859 1.8e-07 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_00860 7.2e-10
HCHLGBMO_00864 4.3e-98 S AntA/AntB antirepressor
HCHLGBMO_00865 2.9e-12
HCHLGBMO_00870 1.3e-81 S DNA binding
HCHLGBMO_00871 9.5e-12 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_00872 6.5e-23 K Cro/C1-type HTH DNA-binding domain
HCHLGBMO_00873 3.3e-18 S Pfam:Peptidase_M78
HCHLGBMO_00878 1.6e-20 S YjcQ protein
HCHLGBMO_00879 4.2e-180 sip L Belongs to the 'phage' integrase family
HCHLGBMO_00880 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCHLGBMO_00881 3.4e-15 K FCD
HCHLGBMO_00882 4.7e-26 K FCD
HCHLGBMO_00883 1.6e-60 clcA P chloride
HCHLGBMO_00884 8.6e-119 clcA P chloride
HCHLGBMO_00885 2.5e-115 L PFAM Integrase catalytic
HCHLGBMO_00886 1.2e-57 L Transposase
HCHLGBMO_00887 3.3e-153 L Transposase
HCHLGBMO_00888 2.2e-102 L Integrase
HCHLGBMO_00889 8e-69 T Toxin-antitoxin system, toxin component, MazF family
HCHLGBMO_00890 1.3e-30
HCHLGBMO_00891 1.3e-190 L Transposase and inactivated derivatives, IS30 family
HCHLGBMO_00892 2.8e-33 scrR K Periplasmic binding protein domain
HCHLGBMO_00893 2e-37 scrR K Periplasmic binding protein domain
HCHLGBMO_00894 5.8e-73 S domain protein
HCHLGBMO_00897 4.5e-43
HCHLGBMO_00898 1.9e-75 M LysM domain
HCHLGBMO_00899 4e-33 3.5.1.28 NU amidase activity
HCHLGBMO_00900 1.3e-157 trsE S COG0433 Predicted ATPase
HCHLGBMO_00901 8.4e-15
HCHLGBMO_00903 1.7e-32 I mechanosensitive ion channel activity
HCHLGBMO_00904 8.9e-86 U TraM recognition site of TraD and TraG
HCHLGBMO_00905 3.2e-19
HCHLGBMO_00907 3.2e-182 M Glycosyl hydrolases family 25
HCHLGBMO_00908 6.1e-27
HCHLGBMO_00909 7e-16
HCHLGBMO_00911 1.7e-16
HCHLGBMO_00913 1.2e-10
HCHLGBMO_00918 1.7e-49
HCHLGBMO_00919 4.3e-35
HCHLGBMO_00920 1.4e-09
HCHLGBMO_00921 8.8e-114 Z012_12235 S Baseplate J-like protein
HCHLGBMO_00922 6.4e-31
HCHLGBMO_00923 1.2e-37
HCHLGBMO_00924 1.9e-102
HCHLGBMO_00925 2.7e-46
HCHLGBMO_00926 3.8e-59 M LysM domain
HCHLGBMO_00927 1e-220 3.4.14.13 M Phage tail tape measure protein TP901
HCHLGBMO_00929 2.9e-09
HCHLGBMO_00930 9.3e-29
HCHLGBMO_00931 3.5e-103 Z012_02110 S Protein of unknown function (DUF3383)
HCHLGBMO_00932 3.3e-31
HCHLGBMO_00933 1.6e-25
HCHLGBMO_00934 1e-29
HCHLGBMO_00935 9.2e-20 S Protein of unknown function (DUF4054)
HCHLGBMO_00936 2.4e-93 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
HCHLGBMO_00937 4.1e-34
HCHLGBMO_00938 1.6e-57 S Uncharacterized protein conserved in bacteria (DUF2213)
HCHLGBMO_00939 5e-12 S Lysin motif
HCHLGBMO_00940 1.3e-47 S Phage Mu protein F like protein
HCHLGBMO_00941 6.2e-135 S Protein of unknown function (DUF1073)
HCHLGBMO_00942 1.1e-201 S Terminase-like family
HCHLGBMO_00943 3e-19 ps333 L Terminase small subunit
HCHLGBMO_00946 3.3e-09 arpU S Phage transcriptional regulator, ArpU family
HCHLGBMO_00949 1.4e-218 XK27_11280 S Psort location CytoplasmicMembrane, score
HCHLGBMO_00957 1.2e-100 L Helix-turn-helix domain
HCHLGBMO_00958 5.3e-131 S ERF superfamily
HCHLGBMO_00959 1.6e-128 S Protein of unknown function (DUF1351)
HCHLGBMO_00960 4.6e-45
HCHLGBMO_00962 5.5e-18
HCHLGBMO_00963 1.8e-31 S Helix-turn-helix domain
HCHLGBMO_00969 2.4e-93 S DNA binding
HCHLGBMO_00970 1.4e-17 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_00971 8.8e-22 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_00972 2.4e-07 S Pfam:DUF955
HCHLGBMO_00973 5.6e-08 M Host cell surface-exposed lipoprotein
HCHLGBMO_00974 6.2e-12
HCHLGBMO_00975 3.7e-93 sip L Belongs to the 'phage' integrase family
HCHLGBMO_00976 4.3e-48 U TraM recognition site of TraD and TraG
HCHLGBMO_00980 6.6e-38 M domain protein
HCHLGBMO_00981 1.6e-42 M domain protein
HCHLGBMO_00983 7e-83 S Phage portal protein
HCHLGBMO_00984 1.4e-74 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HCHLGBMO_00985 3.5e-50 S peptidase activity
HCHLGBMO_00986 7.3e-17 S Phage gp6-like head-tail connector protein
HCHLGBMO_00988 4.1e-23 S Bacteriophage HK97-gp10, putative tail-component
HCHLGBMO_00989 8.1e-13 S Protein of unknown function (DUF806)
HCHLGBMO_00990 1e-25 S Phage tail tube protein
HCHLGBMO_00993 7e-158 M Phage tail tape measure protein TP901
HCHLGBMO_00994 8.6e-38 S phage tail
HCHLGBMO_00995 1.4e-167 S Phage minor structural protein
HCHLGBMO_00998 1.1e-42 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HCHLGBMO_00999 3.3e-241 V N-6 DNA Methylase
HCHLGBMO_01000 2.4e-99 L An automated process has identified a potential problem with this gene model
HCHLGBMO_01001 8.3e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HCHLGBMO_01002 3.5e-57 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCHLGBMO_01003 6.5e-18 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HCHLGBMO_01004 9.7e-205 gatC G PTS system sugar-specific permease component
HCHLGBMO_01005 1.2e-24 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2
HCHLGBMO_01007 7.9e-16 L An automated process has identified a potential problem with this gene model
HCHLGBMO_01008 9.4e-51 L An automated process has identified a potential problem with this gene model
HCHLGBMO_01010 1e-66 doc S Fic/DOC family
HCHLGBMO_01011 4.1e-34
HCHLGBMO_01013 1.1e-23 S CAAX protease self-immunity
HCHLGBMO_01015 3.7e-133 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HCHLGBMO_01017 1.1e-25
HCHLGBMO_01018 1.2e-77 K DNA-templated transcription, initiation
HCHLGBMO_01019 5.3e-41
HCHLGBMO_01021 1.2e-132 S SLAP domain
HCHLGBMO_01023 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCHLGBMO_01024 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HCHLGBMO_01025 8.8e-177 yjbQ P TrkA C-terminal domain protein
HCHLGBMO_01026 1.9e-113 yjbQ P TrkA C-terminal domain protein
HCHLGBMO_01027 9.7e-107 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HCHLGBMO_01028 7.8e-161 S Oxidoreductase family, NAD-binding Rossmann fold
HCHLGBMO_01029 1.7e-129
HCHLGBMO_01030 2.1e-116
HCHLGBMO_01031 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCHLGBMO_01032 1.4e-98 G Aldose 1-epimerase
HCHLGBMO_01033 1.8e-201 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HCHLGBMO_01034 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCHLGBMO_01035 0.0 XK27_08315 M Sulfatase
HCHLGBMO_01038 3.4e-17 CO COG0526, thiol-disulfide isomerase and thioredoxins
HCHLGBMO_01044 6.3e-54 S COG0790 FOG TPR repeat, SEL1 subfamily
HCHLGBMO_01045 6e-15 L Protein of unknown function (DUF3991)
HCHLGBMO_01046 1.1e-12 L Protein of unknown function (DUF3991)
HCHLGBMO_01047 2.1e-111 S Fic/DOC family
HCHLGBMO_01048 7.4e-150 fhaB M Rib/alpha-like repeat
HCHLGBMO_01049 2.1e-64 fhaB M Rib/alpha-like repeat
HCHLGBMO_01050 7.7e-22
HCHLGBMO_01051 9.3e-64 L PFAM IS66 Orf2 family protein
HCHLGBMO_01052 8.7e-34 S Transposase C of IS166 homeodomain
HCHLGBMO_01053 1.9e-245 L Transposase IS66 family
HCHLGBMO_01055 1.2e-49 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCHLGBMO_01056 7e-135 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HCHLGBMO_01057 1.3e-68 GM NAD(P)H-binding
HCHLGBMO_01058 3.4e-33 S Domain of unknown function (DUF4440)
HCHLGBMO_01059 6.6e-90 K LysR substrate binding domain
HCHLGBMO_01061 3.3e-45 K Tetracycline repressor, C-terminal all-alpha domain
HCHLGBMO_01062 3.2e-79 S X-Pro dipeptidyl-peptidase (S15 family)
HCHLGBMO_01063 7.7e-10 C Flavodoxin
HCHLGBMO_01064 4.9e-251 ade 3.5.4.2 F Adenine deaminase C-terminal domain
HCHLGBMO_01065 3e-145 potD2 P ABC transporter
HCHLGBMO_01066 1.6e-135 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCHLGBMO_01067 3.7e-84 potC3 E Binding-protein-dependent transport system inner membrane component
HCHLGBMO_01068 1.8e-132 infB M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HCHLGBMO_01069 2.3e-101 L An automated process has identified a potential problem with this gene model
HCHLGBMO_01070 4.6e-25 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HCHLGBMO_01072 6.1e-48 E Pfam:DUF955
HCHLGBMO_01073 1.7e-23 relB L Addiction module antitoxin, RelB DinJ family
HCHLGBMO_01074 9.6e-18 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
HCHLGBMO_01075 2.7e-16 S Phage portal protein
HCHLGBMO_01077 1.4e-83 S Phage Terminase
HCHLGBMO_01078 2.7e-116 S Phage Terminase
HCHLGBMO_01081 3.1e-26 E Zn peptidase
HCHLGBMO_01082 1.1e-14 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_01083 2.5e-20
HCHLGBMO_01084 1.3e-19
HCHLGBMO_01085 2.1e-34 S Domain of unknown function (DUF4417)
HCHLGBMO_01086 3.4e-164 msmX P Belongs to the ABC transporter superfamily
HCHLGBMO_01087 5e-226 L Transposase
HCHLGBMO_01088 8.4e-265 S Fibronectin type III domain
HCHLGBMO_01089 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCHLGBMO_01090 3.4e-53
HCHLGBMO_01092 4.6e-257 pepC 3.4.22.40 E aminopeptidase
HCHLGBMO_01093 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCHLGBMO_01094 5e-301 oppA E ABC transporter, substratebinding protein
HCHLGBMO_01095 1.6e-310 oppA E ABC transporter, substratebinding protein
HCHLGBMO_01096 5.1e-181 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HCHLGBMO_01097 9.2e-36 L An automated process has identified a potential problem with this gene model
HCHLGBMO_01098 3.3e-140 repB EP Plasmid replication protein
HCHLGBMO_01099 2.2e-22
HCHLGBMO_01100 1.3e-149 oppA E ABC transporter substrate-binding protein
HCHLGBMO_01101 2.2e-54 oppA E ABC transporter substrate-binding protein
HCHLGBMO_01102 3.7e-174 L Bifunctional protein
HCHLGBMO_01103 5.8e-100 L Helix-turn-helix domain
HCHLGBMO_01104 3.8e-160 L hmm pf00665
HCHLGBMO_01105 3e-112 L PFAM transposase IS116 IS110 IS902
HCHLGBMO_01106 8.8e-29
HCHLGBMO_01109 8.6e-56 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_01110 3.3e-127 L PFAM transposase IS116 IS110 IS902
HCHLGBMO_01111 1.4e-31 O OsmC-like protein
HCHLGBMO_01113 1.5e-36 oppA E ABC transporter substrate-binding protein
HCHLGBMO_01114 3.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCHLGBMO_01115 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCHLGBMO_01116 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCHLGBMO_01117 2.7e-199 oppD P Belongs to the ABC transporter superfamily
HCHLGBMO_01118 1.9e-175 oppF P Belongs to the ABC transporter superfamily
HCHLGBMO_01119 5.2e-256 pepC 3.4.22.40 E aminopeptidase
HCHLGBMO_01120 3.9e-72 hsp O Belongs to the small heat shock protein (HSP20) family
HCHLGBMO_01121 1.3e-28 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCHLGBMO_01122 8e-12 relB L RelB antitoxin
HCHLGBMO_01123 3.2e-15 relB L RelB antitoxin
HCHLGBMO_01124 1.6e-35 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HCHLGBMO_01125 3.7e-39 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HCHLGBMO_01126 1.8e-79
HCHLGBMO_01127 1.2e-10
HCHLGBMO_01128 4e-60 L Resolvase, N terminal domain
HCHLGBMO_01129 6.7e-125 L DDE superfamily endonuclease
HCHLGBMO_01130 2e-199 L Transposase and inactivated derivatives, IS30 family
HCHLGBMO_01131 2.6e-35 yaaA S S4 domain protein YaaA
HCHLGBMO_01132 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCHLGBMO_01133 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCHLGBMO_01134 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCHLGBMO_01135 1.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HCHLGBMO_01136 2.7e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCHLGBMO_01137 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCHLGBMO_01138 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HCHLGBMO_01139 4.2e-30 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HCHLGBMO_01140 5.7e-69 rplI J Binds to the 23S rRNA
HCHLGBMO_01141 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HCHLGBMO_01142 2.3e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HCHLGBMO_01143 5.2e-170 degV S DegV family
HCHLGBMO_01144 2.5e-135 V ABC transporter transmembrane region
HCHLGBMO_01145 6.7e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HCHLGBMO_01147 1.4e-16
HCHLGBMO_01148 1.6e-227 I Protein of unknown function (DUF2974)
HCHLGBMO_01149 9.2e-119 yhiD S MgtC family
HCHLGBMO_01151 3.8e-24 S SLAP domain
HCHLGBMO_01152 4.3e-24 S SLAP domain
HCHLGBMO_01153 6e-112
HCHLGBMO_01155 1.7e-110 E Belongs to the SOS response-associated peptidase family
HCHLGBMO_01156 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCHLGBMO_01157 4e-89 comEB 3.5.4.12 F MafB19-like deaminase
HCHLGBMO_01158 2e-103 S TPM domain
HCHLGBMO_01159 2.4e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HCHLGBMO_01160 2.5e-311 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HCHLGBMO_01161 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCHLGBMO_01162 1e-147 tatD L hydrolase, TatD family
HCHLGBMO_01163 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCHLGBMO_01164 6.7e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCHLGBMO_01165 4.5e-39 veg S Biofilm formation stimulator VEG
HCHLGBMO_01166 1.5e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HCHLGBMO_01167 2.6e-173 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCHLGBMO_01168 4e-80
HCHLGBMO_01169 7.3e-290 S SLAP domain
HCHLGBMO_01170 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCHLGBMO_01171 4.2e-172 2.7.1.2 GK ROK family
HCHLGBMO_01172 2.1e-42
HCHLGBMO_01173 3.6e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCHLGBMO_01174 6.9e-69 S Domain of unknown function (DUF1934)
HCHLGBMO_01175 1.5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCHLGBMO_01176 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCHLGBMO_01177 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCHLGBMO_01178 1.8e-74 K acetyltransferase
HCHLGBMO_01179 5.7e-285 pipD E Dipeptidase
HCHLGBMO_01180 2.5e-152 msmR K AraC-like ligand binding domain
HCHLGBMO_01181 1.4e-226 pbuX F xanthine permease
HCHLGBMO_01182 2e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCHLGBMO_01183 2.4e-43 K Helix-turn-helix
HCHLGBMO_01184 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HCHLGBMO_01186 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HCHLGBMO_01187 8.7e-117 3.2.1.18 GH33 M Rib/alpha-like repeat
HCHLGBMO_01188 4.5e-185 3.2.1.18 GH33 M Rib/alpha-like repeat
HCHLGBMO_01190 7.8e-78 2.5.1.74 H UbiA prenyltransferase family
HCHLGBMO_01191 1e-95
HCHLGBMO_01192 1.1e-140 yfeO P Voltage gated chloride channel
HCHLGBMO_01193 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
HCHLGBMO_01194 1.4e-51
HCHLGBMO_01195 2.1e-42
HCHLGBMO_01196 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCHLGBMO_01197 9.5e-297 ybeC E amino acid
HCHLGBMO_01198 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
HCHLGBMO_01199 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HCHLGBMO_01200 2.5e-39 rpmE2 J Ribosomal protein L31
HCHLGBMO_01201 1.3e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCHLGBMO_01202 4.8e-250 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCHLGBMO_01203 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCHLGBMO_01204 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCHLGBMO_01205 1.6e-123 S (CBS) domain
HCHLGBMO_01206 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HCHLGBMO_01207 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCHLGBMO_01208 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCHLGBMO_01209 1.6e-33 yabO J S4 domain protein
HCHLGBMO_01210 6.8e-60 divIC D Septum formation initiator
HCHLGBMO_01211 1.8e-62 yabR J S1 RNA binding domain
HCHLGBMO_01212 1.5e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCHLGBMO_01213 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCHLGBMO_01214 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCHLGBMO_01215 1.1e-192 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCHLGBMO_01216 1.7e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HCHLGBMO_01217 3.7e-228 L COG2963 Transposase and inactivated derivatives
HCHLGBMO_01218 1.4e-83 K FR47-like protein
HCHLGBMO_01219 1.6e-08
HCHLGBMO_01220 1.6e-08
HCHLGBMO_01222 1.3e-81 yebR 1.8.4.14 T GAF domain-containing protein
HCHLGBMO_01223 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCHLGBMO_01224 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCHLGBMO_01225 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCHLGBMO_01226 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HCHLGBMO_01227 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCHLGBMO_01228 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCHLGBMO_01229 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCHLGBMO_01230 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HCHLGBMO_01231 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCHLGBMO_01232 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
HCHLGBMO_01233 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCHLGBMO_01234 7.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCHLGBMO_01235 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCHLGBMO_01236 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCHLGBMO_01237 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCHLGBMO_01238 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCHLGBMO_01239 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HCHLGBMO_01240 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCHLGBMO_01241 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCHLGBMO_01242 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCHLGBMO_01243 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCHLGBMO_01244 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCHLGBMO_01245 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCHLGBMO_01246 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCHLGBMO_01247 1.1e-54 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCHLGBMO_01248 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCHLGBMO_01249 2.3e-24 rpmD J Ribosomal protein L30
HCHLGBMO_01250 2.6e-71 rplO J Binds to the 23S rRNA
HCHLGBMO_01251 1.1e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCHLGBMO_01252 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCHLGBMO_01253 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCHLGBMO_01254 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HCHLGBMO_01255 3.6e-55 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCHLGBMO_01256 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCHLGBMO_01257 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCHLGBMO_01258 1.4e-60 rplQ J Ribosomal protein L17
HCHLGBMO_01259 3.7e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCHLGBMO_01260 4.6e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCHLGBMO_01261 7.2e-136 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCHLGBMO_01262 8.4e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCHLGBMO_01263 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCHLGBMO_01264 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
HCHLGBMO_01265 3.6e-183 L Phage integrase family
HCHLGBMO_01266 2.8e-65 K LytTr DNA-binding domain
HCHLGBMO_01267 6e-49 S Protein of unknown function (DUF3021)
HCHLGBMO_01268 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HCHLGBMO_01269 1.9e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HCHLGBMO_01270 6e-132 S membrane transporter protein
HCHLGBMO_01271 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
HCHLGBMO_01272 7.3e-161 czcD P cation diffusion facilitator family transporter
HCHLGBMO_01273 1.4e-23
HCHLGBMO_01274 2.6e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCHLGBMO_01275 5.4e-183 S AAA domain
HCHLGBMO_01276 3.3e-44
HCHLGBMO_01277 4.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
HCHLGBMO_01278 2.7e-51
HCHLGBMO_01279 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HCHLGBMO_01280 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCHLGBMO_01281 1.9e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCHLGBMO_01282 3.4e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCHLGBMO_01283 6.7e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCHLGBMO_01284 6.6e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCHLGBMO_01285 4.2e-95 sigH K Belongs to the sigma-70 factor family
HCHLGBMO_01286 1.7e-34
HCHLGBMO_01287 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HCHLGBMO_01288 2.1e-70 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCHLGBMO_01289 1.6e-246 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCHLGBMO_01290 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCHLGBMO_01291 3.1e-101 nusG K Participates in transcription elongation, termination and antitermination
HCHLGBMO_01292 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCHLGBMO_01293 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCHLGBMO_01294 2.8e-157 pstS P Phosphate
HCHLGBMO_01295 4.3e-162 pstC P probably responsible for the translocation of the substrate across the membrane
HCHLGBMO_01296 1e-154 pstA P Phosphate transport system permease protein PstA
HCHLGBMO_01297 1.1e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCHLGBMO_01298 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCHLGBMO_01299 4.1e-14 phoU P Plays a role in the regulation of phosphate uptake
HCHLGBMO_01300 1.5e-11 GT2,GT4 M family 8
HCHLGBMO_01301 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCHLGBMO_01302 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCHLGBMO_01303 5.1e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HCHLGBMO_01304 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
HCHLGBMO_01305 9e-26
HCHLGBMO_01306 1.7e-174 L COG3385 FOG Transposase and inactivated derivatives
HCHLGBMO_01307 1.3e-84 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCHLGBMO_01308 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCHLGBMO_01309 1.6e-45 2.4.1.58 GT8 M family 8
HCHLGBMO_01310 2.5e-13 K Helix-turn-helix domain
HCHLGBMO_01311 1.9e-25 S CAAX protease self-immunity
HCHLGBMO_01312 1.4e-22 S CAAX protease self-immunity
HCHLGBMO_01313 3.8e-25 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_01315 1.6e-96 ybaT E Amino acid permease
HCHLGBMO_01316 6.5e-07 S LPXTG cell wall anchor motif
HCHLGBMO_01317 2.6e-146 S Putative ABC-transporter type IV
HCHLGBMO_01318 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HCHLGBMO_01319 9.4e-43 2.4.1.58 GT8 M family 8
HCHLGBMO_01320 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HCHLGBMO_01321 2.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCHLGBMO_01322 2.4e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCHLGBMO_01323 1.1e-34 S Protein of unknown function (DUF2508)
HCHLGBMO_01324 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCHLGBMO_01325 2.2e-51 yaaQ S Cyclic-di-AMP receptor
HCHLGBMO_01326 3.7e-154 holB 2.7.7.7 L DNA polymerase III
HCHLGBMO_01327 1.8e-59 yabA L Involved in initiation control of chromosome replication
HCHLGBMO_01328 1.5e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCHLGBMO_01329 8.4e-131 fat 3.1.2.21 I Acyl-ACP thioesterase
HCHLGBMO_01330 2.2e-85 S ECF transporter, substrate-specific component
HCHLGBMO_01331 8.2e-134 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HCHLGBMO_01332 4.8e-96 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HCHLGBMO_01333 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCHLGBMO_01334 1.3e-51 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HCHLGBMO_01335 3.2e-170 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HCHLGBMO_01336 8.1e-286 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HCHLGBMO_01337 0.0 uup S ABC transporter, ATP-binding protein
HCHLGBMO_01338 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCHLGBMO_01339 1.1e-183 scrR K helix_turn _helix lactose operon repressor
HCHLGBMO_01340 3.7e-295 scrB 3.2.1.26 GH32 G invertase
HCHLGBMO_01341 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HCHLGBMO_01342 2.3e-181 M CHAP domain
HCHLGBMO_01343 3.5e-75
HCHLGBMO_01344 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCHLGBMO_01345 2.6e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCHLGBMO_01346 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCHLGBMO_01347 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCHLGBMO_01348 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCHLGBMO_01349 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCHLGBMO_01350 9.6e-41 yajC U Preprotein translocase
HCHLGBMO_01351 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCHLGBMO_01352 1.6e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCHLGBMO_01353 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HCHLGBMO_01354 4.7e-228 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCHLGBMO_01355 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCHLGBMO_01356 2e-42 yrzL S Belongs to the UPF0297 family
HCHLGBMO_01357 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCHLGBMO_01358 1.1e-50 yrzB S Belongs to the UPF0473 family
HCHLGBMO_01359 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCHLGBMO_01360 3.5e-54 trxA O Belongs to the thioredoxin family
HCHLGBMO_01361 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCHLGBMO_01362 1.1e-71 yslB S Protein of unknown function (DUF2507)
HCHLGBMO_01363 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HCHLGBMO_01364 6.2e-111 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCHLGBMO_01365 4.4e-40 ropB K Helix-turn-helix domain
HCHLGBMO_01367 8.7e-19 spaC2 V Lanthionine synthetase C-like protein
HCHLGBMO_01368 3.4e-99
HCHLGBMO_01369 1.4e-133
HCHLGBMO_01370 3.1e-100 V ATPases associated with a variety of cellular activities
HCHLGBMO_01371 1.3e-146 ykuT M mechanosensitive ion channel
HCHLGBMO_01372 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HCHLGBMO_01373 1.3e-36
HCHLGBMO_01374 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HCHLGBMO_01375 3.2e-181 ccpA K catabolite control protein A
HCHLGBMO_01376 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCHLGBMO_01377 4.3e-55
HCHLGBMO_01378 9.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HCHLGBMO_01379 1.7e-105 yutD S Protein of unknown function (DUF1027)
HCHLGBMO_01380 6.9e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCHLGBMO_01381 3.7e-100 S Protein of unknown function (DUF1461)
HCHLGBMO_01382 2.6e-115 dedA S SNARE-like domain protein
HCHLGBMO_01383 8e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HCHLGBMO_01407 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HCHLGBMO_01408 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
HCHLGBMO_01409 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCHLGBMO_01410 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCHLGBMO_01411 1.7e-29 secG U Preprotein translocase
HCHLGBMO_01412 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCHLGBMO_01413 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HCHLGBMO_01415 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HCHLGBMO_01416 1.7e-129 manY G PTS system
HCHLGBMO_01417 1e-173 manN G system, mannose fructose sorbose family IID component
HCHLGBMO_01418 1.1e-62 manO S Domain of unknown function (DUF956)
HCHLGBMO_01419 3.3e-158 K Transcriptional regulator
HCHLGBMO_01420 7e-66 maa S transferase hexapeptide repeat
HCHLGBMO_01421 8e-244 cycA E Amino acid permease
HCHLGBMO_01422 2.6e-258 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HCHLGBMO_01423 1.8e-237 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HCHLGBMO_01424 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCHLGBMO_01425 0.0 mtlR K Mga helix-turn-helix domain
HCHLGBMO_01426 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HCHLGBMO_01427 1e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCHLGBMO_01428 2.9e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HCHLGBMO_01429 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
HCHLGBMO_01430 1.4e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
HCHLGBMO_01431 2.1e-32
HCHLGBMO_01432 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HCHLGBMO_01433 2.3e-156 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_01434 7.3e-29 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S regulation of response to stimulus
HCHLGBMO_01435 5.2e-117 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HCHLGBMO_01436 1.2e-210 oppA E ABC transporter substrate-binding protein
HCHLGBMO_01437 2.7e-109 oppA E ABC transporter substrate-binding protein
HCHLGBMO_01438 1.9e-176 K AI-2E family transporter
HCHLGBMO_01439 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HCHLGBMO_01440 4.1e-18
HCHLGBMO_01441 5.2e-248 G Major Facilitator
HCHLGBMO_01442 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
HCHLGBMO_01443 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HCHLGBMO_01444 1.7e-174 ABC-SBP S ABC transporter
HCHLGBMO_01445 1e-257 V ABC transporter transmembrane region
HCHLGBMO_01446 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HCHLGBMO_01447 0.0 S TerB-C domain
HCHLGBMO_01448 3.5e-244 P P-loop Domain of unknown function (DUF2791)
HCHLGBMO_01449 0.0 lhr L DEAD DEAH box helicase
HCHLGBMO_01450 1.4e-60
HCHLGBMO_01451 4.1e-198 amtB P ammonium transporter
HCHLGBMO_01452 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HCHLGBMO_01454 6.2e-59 psiE S Phosphate-starvation-inducible E
HCHLGBMO_01455 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
HCHLGBMO_01456 2.9e-69 S Iron-sulphur cluster biosynthesis
HCHLGBMO_01458 2.3e-30
HCHLGBMO_01459 2.3e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HCHLGBMO_01460 6.2e-12
HCHLGBMO_01461 1.8e-125 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCHLGBMO_01462 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCHLGBMO_01463 5.8e-78 M LysM domain protein
HCHLGBMO_01464 4.7e-159 D nuclear chromosome segregation
HCHLGBMO_01465 1.2e-105 G Phosphoglycerate mutase family
HCHLGBMO_01466 2.8e-88 G Histidine phosphatase superfamily (branch 1)
HCHLGBMO_01467 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HCHLGBMO_01468 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCHLGBMO_01470 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HCHLGBMO_01471 1.4e-209 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HCHLGBMO_01472 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HCHLGBMO_01473 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HCHLGBMO_01474 4.4e-144 K SIS domain
HCHLGBMO_01475 6.7e-228 slpX S SLAP domain
HCHLGBMO_01476 3.7e-22 3.6.4.12 S transposase or invertase
HCHLGBMO_01477 7.7e-12
HCHLGBMO_01478 1.1e-240 npr 1.11.1.1 C NADH oxidase
HCHLGBMO_01481 9.3e-300 oppA2 E ABC transporter, substratebinding protein
HCHLGBMO_01482 2.5e-179
HCHLGBMO_01483 4.6e-123 gntR1 K UTRA
HCHLGBMO_01484 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HCHLGBMO_01485 1.2e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HCHLGBMO_01486 2.9e-204 csaB M Glycosyl transferases group 1
HCHLGBMO_01487 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCHLGBMO_01488 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCHLGBMO_01489 1.3e-202 tnpB L Putative transposase DNA-binding domain
HCHLGBMO_01490 0.0 pacL 3.6.3.8 P P-type ATPase
HCHLGBMO_01491 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCHLGBMO_01492 3e-257 epsU S Polysaccharide biosynthesis protein
HCHLGBMO_01493 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
HCHLGBMO_01494 4.8e-84 ydcK S Belongs to the SprT family
HCHLGBMO_01496 2.5e-86 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HCHLGBMO_01497 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HCHLGBMO_01498 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCHLGBMO_01499 5.8e-203 camS S sex pheromone
HCHLGBMO_01500 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCHLGBMO_01501 5.2e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCHLGBMO_01502 1.2e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCHLGBMO_01503 2.7e-171 yegS 2.7.1.107 G Lipid kinase
HCHLGBMO_01504 7.2e-18
HCHLGBMO_01505 2.9e-66 K transcriptional regulator
HCHLGBMO_01506 1.2e-105 ybhL S Belongs to the BI1 family
HCHLGBMO_01507 4.5e-50
HCHLGBMO_01508 1.3e-230 nhaC C Na H antiporter NhaC
HCHLGBMO_01509 1.6e-199 pbpX V Beta-lactamase
HCHLGBMO_01510 5.8e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCHLGBMO_01511 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
HCHLGBMO_01516 1.2e-258 emrY EGP Major facilitator Superfamily
HCHLGBMO_01517 2.3e-90 yxdD K Bacterial regulatory proteins, tetR family
HCHLGBMO_01518 0.0 4.2.1.53 S Myosin-crossreactive antigen
HCHLGBMO_01519 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
HCHLGBMO_01520 7.8e-157 S reductase
HCHLGBMO_01521 2e-29
HCHLGBMO_01522 2.9e-287 K Putative DNA-binding domain
HCHLGBMO_01523 2.9e-238 pyrP F Permease
HCHLGBMO_01524 4.7e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCHLGBMO_01525 7.8e-261 emrY EGP Major facilitator Superfamily
HCHLGBMO_01526 1.1e-217 mdtG EGP Major facilitator Superfamily
HCHLGBMO_01527 6.6e-120
HCHLGBMO_01528 1.9e-43
HCHLGBMO_01529 1.7e-209 pepA E M42 glutamyl aminopeptidase
HCHLGBMO_01530 2.2e-311 ybiT S ABC transporter, ATP-binding protein
HCHLGBMO_01531 5.9e-174 S Aldo keto reductase
HCHLGBMO_01532 6.1e-151
HCHLGBMO_01533 9.8e-239 steT E amino acid
HCHLGBMO_01534 8.6e-243 steT E amino acid
HCHLGBMO_01535 4.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
HCHLGBMO_01536 1.9e-147 glnH ET ABC transporter
HCHLGBMO_01537 1.4e-80 K Transcriptional regulator, MarR family
HCHLGBMO_01538 1.5e-308 XK27_09600 V ABC transporter, ATP-binding protein
HCHLGBMO_01539 0.0 V ABC transporter transmembrane region
HCHLGBMO_01540 8.4e-102 S ABC-type cobalt transport system, permease component
HCHLGBMO_01541 4.7e-85 G MFS/sugar transport protein
HCHLGBMO_01542 2.3e-151 G MFS/sugar transport protein
HCHLGBMO_01543 4.7e-114 udk 2.7.1.48 F Zeta toxin
HCHLGBMO_01544 1.9e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCHLGBMO_01545 3.4e-149 glnH ET ABC transporter substrate-binding protein
HCHLGBMO_01546 9.7e-91 gluC P ABC transporter permease
HCHLGBMO_01547 6.8e-108 glnP P ABC transporter permease
HCHLGBMO_01548 1.1e-164 S Protein of unknown function (DUF2974)
HCHLGBMO_01549 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HCHLGBMO_01550 2e-155 P CorA-like Mg2+ transporter protein
HCHLGBMO_01551 1.2e-160 yvgN C Aldo keto reductase
HCHLGBMO_01552 0.0 tetP J elongation factor G
HCHLGBMO_01553 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
HCHLGBMO_01554 7.6e-134 EGP Major facilitator Superfamily
HCHLGBMO_01555 1.4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCHLGBMO_01558 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
HCHLGBMO_01559 1.3e-273 E amino acid
HCHLGBMO_01560 0.0 L Helicase C-terminal domain protein
HCHLGBMO_01561 4.8e-205 pbpX1 V Beta-lactamase
HCHLGBMO_01562 5.1e-226 N Uncharacterized conserved protein (DUF2075)
HCHLGBMO_01563 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HCHLGBMO_01565 2e-210 S Uncharacterized protein conserved in bacteria (DUF2325)
HCHLGBMO_01566 1.3e-235 G Bacterial extracellular solute-binding protein
HCHLGBMO_01567 1.3e-161 2.7.7.12 C Domain of unknown function (DUF4931)
HCHLGBMO_01568 5.4e-167 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCHLGBMO_01569 3.4e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCHLGBMO_01570 0.0 kup P Transport of potassium into the cell
HCHLGBMO_01571 9.1e-175 rihB 3.2.2.1 F Nucleoside
HCHLGBMO_01572 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
HCHLGBMO_01573 1e-153 S hydrolase
HCHLGBMO_01574 2.5e-59 S Enterocin A Immunity
HCHLGBMO_01575 3.1e-136 glcR K DeoR C terminal sensor domain
HCHLGBMO_01576 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HCHLGBMO_01577 2e-160 rssA S Phospholipase, patatin family
HCHLGBMO_01578 7.8e-146 S hydrolase
HCHLGBMO_01579 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HCHLGBMO_01580 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
HCHLGBMO_01581 1.6e-80
HCHLGBMO_01582 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCHLGBMO_01583 2.1e-39
HCHLGBMO_01584 3.9e-119 C nitroreductase
HCHLGBMO_01585 1.7e-249 yhdP S Transporter associated domain
HCHLGBMO_01586 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HCHLGBMO_01587 2e-130 1.3.5.4 C FAD binding domain
HCHLGBMO_01588 1.9e-186 1.3.5.4 C FAD binding domain
HCHLGBMO_01589 1.1e-87 L PFAM transposase, IS4 family protein
HCHLGBMO_01590 1.2e-49 L PFAM transposase, IS4 family protein
HCHLGBMO_01591 0.0 1.3.5.4 C FAD binding domain
HCHLGBMO_01592 2.8e-230 potE E amino acid
HCHLGBMO_01593 1.1e-130 M Glycosyl hydrolases family 25
HCHLGBMO_01594 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
HCHLGBMO_01595 1.8e-248 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCHLGBMO_01597 5.9e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCHLGBMO_01598 3.1e-87 gtcA S Teichoic acid glycosylation protein
HCHLGBMO_01599 4.1e-80 fld C Flavodoxin
HCHLGBMO_01600 6.5e-164 map 3.4.11.18 E Methionine Aminopeptidase
HCHLGBMO_01601 8e-163 yihY S Belongs to the UPF0761 family
HCHLGBMO_01602 7.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HCHLGBMO_01603 5.6e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HCHLGBMO_01604 5.9e-214 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HCHLGBMO_01605 1.2e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HCHLGBMO_01606 1e-44
HCHLGBMO_01607 2.9e-27 D Alpha beta
HCHLGBMO_01608 2.2e-119 D Alpha beta
HCHLGBMO_01609 1.2e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCHLGBMO_01610 3e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
HCHLGBMO_01611 7.8e-85
HCHLGBMO_01612 1.6e-74
HCHLGBMO_01613 1.2e-141 hlyX S Transporter associated domain
HCHLGBMO_01614 2.1e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HCHLGBMO_01615 8.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
HCHLGBMO_01616 0.0 clpE O Belongs to the ClpA ClpB family
HCHLGBMO_01617 8.5e-41 ptsH G phosphocarrier protein HPR
HCHLGBMO_01618 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCHLGBMO_01619 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCHLGBMO_01620 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HCHLGBMO_01621 3.3e-122 coiA 3.6.4.12 S Competence protein
HCHLGBMO_01622 4e-13 coiA 3.6.4.12 S Competence protein
HCHLGBMO_01623 4.6e-114 yjbH Q Thioredoxin
HCHLGBMO_01624 5.2e-110 yjbK S CYTH
HCHLGBMO_01625 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
HCHLGBMO_01626 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCHLGBMO_01627 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCHLGBMO_01628 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HCHLGBMO_01629 4.2e-92 S SNARE associated Golgi protein
HCHLGBMO_01630 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HCHLGBMO_01631 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HCHLGBMO_01632 2.6e-214 yubA S AI-2E family transporter
HCHLGBMO_01633 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCHLGBMO_01634 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
HCHLGBMO_01635 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HCHLGBMO_01636 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HCHLGBMO_01637 1.9e-236 S Peptidase M16
HCHLGBMO_01638 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
HCHLGBMO_01639 2.1e-95 ymfM S Helix-turn-helix domain
HCHLGBMO_01640 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCHLGBMO_01641 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCHLGBMO_01642 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
HCHLGBMO_01643 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
HCHLGBMO_01644 5.1e-119 yvyE 3.4.13.9 S YigZ family
HCHLGBMO_01645 4.7e-246 comFA L Helicase C-terminal domain protein
HCHLGBMO_01646 9.4e-132 comFC S Competence protein
HCHLGBMO_01647 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCHLGBMO_01648 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCHLGBMO_01649 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCHLGBMO_01650 5.1e-17
HCHLGBMO_01651 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCHLGBMO_01652 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCHLGBMO_01653 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HCHLGBMO_01654 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCHLGBMO_01655 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HCHLGBMO_01656 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCHLGBMO_01657 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCHLGBMO_01658 4.1e-90 S Short repeat of unknown function (DUF308)
HCHLGBMO_01659 6.2e-165 rapZ S Displays ATPase and GTPase activities
HCHLGBMO_01660 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HCHLGBMO_01661 4.7e-171 whiA K May be required for sporulation
HCHLGBMO_01662 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCHLGBMO_01663 0.0 S SH3-like domain
HCHLGBMO_01664 1.4e-16 ybbL S ABC transporter, ATP-binding protein
HCHLGBMO_01665 3.1e-84 ybbL S ABC transporter, ATP-binding protein
HCHLGBMO_01666 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
HCHLGBMO_01667 3.1e-48 S Domain of unknown function (DUF4811)
HCHLGBMO_01668 1.4e-262 lmrB EGP Major facilitator Superfamily
HCHLGBMO_01669 4.2e-77 K MerR HTH family regulatory protein
HCHLGBMO_01670 3.1e-139 S Cysteine-rich secretory protein family
HCHLGBMO_01671 4.6e-274 ycaM E amino acid
HCHLGBMO_01672 9e-113
HCHLGBMO_01673 8.5e-156
HCHLGBMO_01675 3.3e-189 cggR K Putative sugar-binding domain
HCHLGBMO_01676 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCHLGBMO_01677 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HCHLGBMO_01678 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCHLGBMO_01679 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
HCHLGBMO_01680 5.9e-13 K Acetyltransferase (GNAT) domain
HCHLGBMO_01681 1.9e-12 L Transposase
HCHLGBMO_01682 1.4e-16 L Transposase
HCHLGBMO_01683 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HCHLGBMO_01684 5.2e-68 L haloacid dehalogenase-like hydrolase
HCHLGBMO_01685 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HCHLGBMO_01686 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HCHLGBMO_01687 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HCHLGBMO_01688 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HCHLGBMO_01689 1.3e-231 ulaA S PTS system sugar-specific permease component
HCHLGBMO_01690 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCHLGBMO_01691 8.1e-175 ulaG S Beta-lactamase superfamily domain
HCHLGBMO_01692 1.2e-94
HCHLGBMO_01693 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HCHLGBMO_01694 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCHLGBMO_01695 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HCHLGBMO_01696 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HCHLGBMO_01697 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
HCHLGBMO_01698 7.8e-163 murB 1.3.1.98 M Cell wall formation
HCHLGBMO_01699 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCHLGBMO_01700 1.3e-129 potB P ABC transporter permease
HCHLGBMO_01701 4.8e-127 potC P ABC transporter permease
HCHLGBMO_01702 7.3e-208 potD P ABC transporter
HCHLGBMO_01703 7.1e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCHLGBMO_01704 2e-172 ybbR S YbbR-like protein
HCHLGBMO_01705 2e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCHLGBMO_01706 1.4e-147 S hydrolase
HCHLGBMO_01707 1.8e-75 K Penicillinase repressor
HCHLGBMO_01708 1.6e-118
HCHLGBMO_01709 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCHLGBMO_01710 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HCHLGBMO_01711 8.3e-143 licT K CAT RNA binding domain
HCHLGBMO_01712 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCHLGBMO_01713 2e-290 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCHLGBMO_01714 1e-149 D Alpha beta
HCHLGBMO_01715 1.2e-92 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HCHLGBMO_01716 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HCHLGBMO_01717 3.4e-66 ica2 GT2 M Glycosyl transferase family group 2
HCHLGBMO_01718 3.9e-43 ica2 GT2 M Glycosyl transferase family group 2
HCHLGBMO_01719 8.2e-36
HCHLGBMO_01720 2.2e-90 2.7.7.65 T GGDEF domain
HCHLGBMO_01721 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCHLGBMO_01723 2e-310 E Amino acid permease
HCHLGBMO_01725 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCHLGBMO_01726 3.5e-101 ylbE GM NAD(P)H-binding
HCHLGBMO_01727 7.6e-94 S VanZ like family
HCHLGBMO_01728 8.9e-133 yebC K Transcriptional regulatory protein
HCHLGBMO_01729 1.7e-179 comGA NU Type II IV secretion system protein
HCHLGBMO_01730 1.7e-171 comGB NU type II secretion system
HCHLGBMO_01731 3.1e-43 comGC U competence protein ComGC
HCHLGBMO_01732 1.8e-69
HCHLGBMO_01733 2.3e-41
HCHLGBMO_01734 3.8e-77 comGF U Putative Competence protein ComGF
HCHLGBMO_01735 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HCHLGBMO_01736 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCHLGBMO_01739 1.4e-153 L Belongs to the 'phage' integrase family
HCHLGBMO_01740 5e-08 S Pfam:DUF955
HCHLGBMO_01741 1.2e-23 K Helix-turn-helix domain
HCHLGBMO_01742 1.2e-21 XK27_07105 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_01743 8.9e-32 K Helix-turn-helix domain
HCHLGBMO_01744 3.2e-24 S Domain of unknown function (DUF771)
HCHLGBMO_01756 2.3e-24 S SLAP domain
HCHLGBMO_01757 6.3e-25 srtA 3.4.22.70 M sortase family
HCHLGBMO_01759 2.9e-226 L Transposase
HCHLGBMO_01760 1e-15 S Domain of Unknown Function with PDB structure (DUF3850)
HCHLGBMO_01762 1.6e-33 M Protein of unknown function (DUF3737)
HCHLGBMO_01764 9e-36 S Cytochrome B5
HCHLGBMO_01765 3.9e-167 arbZ I Phosphate acyltransferases
HCHLGBMO_01766 8.7e-181 arbY M Glycosyl transferase family 8
HCHLGBMO_01767 1.5e-143 arbY M Glycosyl transferase family 8
HCHLGBMO_01768 1.5e-52 M Protein of unknown function (DUF3737)
HCHLGBMO_01769 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
HCHLGBMO_01770 1.5e-79 manA 5.3.1.8 G mannose-6-phosphate isomerase
HCHLGBMO_01771 2.3e-101 manA 5.3.1.8 G mannose-6-phosphate isomerase
HCHLGBMO_01772 7.7e-67 S SdpI/YhfL protein family
HCHLGBMO_01773 4.4e-129 K Transcriptional regulatory protein, C terminal
HCHLGBMO_01774 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
HCHLGBMO_01775 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCHLGBMO_01776 1.1e-104 vanZ V VanZ like family
HCHLGBMO_01777 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
HCHLGBMO_01778 2.4e-216 EGP Major facilitator Superfamily
HCHLGBMO_01780 3.9e-195 ampC V Beta-lactamase
HCHLGBMO_01783 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HCHLGBMO_01784 1.3e-113 tdk 2.7.1.21 F thymidine kinase
HCHLGBMO_01785 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCHLGBMO_01786 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCHLGBMO_01787 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCHLGBMO_01788 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCHLGBMO_01789 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HCHLGBMO_01790 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCHLGBMO_01791 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCHLGBMO_01792 6.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCHLGBMO_01793 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCHLGBMO_01794 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCHLGBMO_01795 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCHLGBMO_01796 2e-71 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HCHLGBMO_01797 2.7e-16 ywzB S Protein of unknown function (DUF1146)
HCHLGBMO_01798 1.2e-177 mbl D Cell shape determining protein MreB Mrl
HCHLGBMO_01799 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HCHLGBMO_01800 3.3e-33 S Protein of unknown function (DUF2969)
HCHLGBMO_01801 4.7e-216 rodA D Belongs to the SEDS family
HCHLGBMO_01802 1.8e-78 usp6 T universal stress protein
HCHLGBMO_01803 8.4e-39
HCHLGBMO_01804 2.2e-238 rarA L recombination factor protein RarA
HCHLGBMO_01805 1.3e-84 yueI S Protein of unknown function (DUF1694)
HCHLGBMO_01806 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCHLGBMO_01807 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCHLGBMO_01808 2.8e-213 iscS2 2.8.1.7 E Aminotransferase class V
HCHLGBMO_01809 4.8e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCHLGBMO_01810 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HCHLGBMO_01811 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCHLGBMO_01812 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HCHLGBMO_01813 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
HCHLGBMO_01814 3.1e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HCHLGBMO_01815 1.5e-94 S Protein of unknown function (DUF3990)
HCHLGBMO_01816 2.9e-44
HCHLGBMO_01818 0.0 3.6.3.8 P P-type ATPase
HCHLGBMO_01819 3.3e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
HCHLGBMO_01820 2.5e-52
HCHLGBMO_01821 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCHLGBMO_01822 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HCHLGBMO_01823 5.7e-126 S Haloacid dehalogenase-like hydrolase
HCHLGBMO_01824 1.1e-08 radC L DNA repair protein
HCHLGBMO_01825 5.8e-89 radC L DNA repair protein
HCHLGBMO_01826 2.4e-176 mreB D cell shape determining protein MreB
HCHLGBMO_01827 2e-147 mreC M Involved in formation and maintenance of cell shape
HCHLGBMO_01828 2.7e-94 mreD
HCHLGBMO_01830 6.4e-54 S Protein of unknown function (DUF3397)
HCHLGBMO_01831 6.3e-78 mraZ K Belongs to the MraZ family
HCHLGBMO_01832 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCHLGBMO_01833 1.8e-54 ftsL D Cell division protein FtsL
HCHLGBMO_01834 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HCHLGBMO_01835 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCHLGBMO_01836 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCHLGBMO_01837 4.9e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCHLGBMO_01838 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCHLGBMO_01839 2.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCHLGBMO_01840 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCHLGBMO_01841 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCHLGBMO_01842 1.7e-45 yggT S YGGT family
HCHLGBMO_01843 8.2e-148 ylmH S S4 domain protein
HCHLGBMO_01844 1.1e-73 gpsB D DivIVA domain protein
HCHLGBMO_01845 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCHLGBMO_01846 1e-30 cspA K 'Cold-shock' DNA-binding domain
HCHLGBMO_01847 9.8e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HCHLGBMO_01848 3e-37
HCHLGBMO_01849 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCHLGBMO_01850 2.1e-216 iscS 2.8.1.7 E Aminotransferase class V
HCHLGBMO_01851 1.4e-56 XK27_04120 S Putative amino acid metabolism
HCHLGBMO_01852 1.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCHLGBMO_01853 1.4e-98 L Helix-turn-helix domain
HCHLGBMO_01854 5.3e-139 L hmm pf00665
HCHLGBMO_01855 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HCHLGBMO_01856 3.1e-105 S Repeat protein
HCHLGBMO_01857 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCHLGBMO_01858 1.6e-294 L Nuclease-related domain
HCHLGBMO_01859 2.7e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HCHLGBMO_01860 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCHLGBMO_01861 9.3e-33 ykzG S Belongs to the UPF0356 family
HCHLGBMO_01862 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCHLGBMO_01863 0.0 typA T GTP-binding protein TypA
HCHLGBMO_01864 2.7e-211 ftsW D Belongs to the SEDS family
HCHLGBMO_01865 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HCHLGBMO_01866 1.3e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HCHLGBMO_01867 1.1e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCHLGBMO_01868 6.9e-187 ylbL T Belongs to the peptidase S16 family
HCHLGBMO_01869 3.1e-79 comEA L Competence protein ComEA
HCHLGBMO_01870 0.0 comEC S Competence protein ComEC
HCHLGBMO_01871 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
HCHLGBMO_01872 6.7e-35 rpsT J Binds directly to 16S ribosomal RNA
HCHLGBMO_01873 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCHLGBMO_01874 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCHLGBMO_01876 8.3e-151
HCHLGBMO_01877 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCHLGBMO_01878 1.2e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCHLGBMO_01879 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCHLGBMO_01880 3.7e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
HCHLGBMO_01881 2.5e-37 yjeM E Amino Acid
HCHLGBMO_01882 7e-40 yjeM E Amino acid permease
HCHLGBMO_01883 2.4e-122 yjeM E Amino Acid
HCHLGBMO_01884 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCHLGBMO_01885 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HCHLGBMO_01886 1.1e-247 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCHLGBMO_01887 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCHLGBMO_01888 7.5e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCHLGBMO_01889 3.7e-176 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCHLGBMO_01890 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCHLGBMO_01891 5.5e-217 aspC 2.6.1.1 E Aminotransferase
HCHLGBMO_01892 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCHLGBMO_01893 4.7e-194 pbpX1 V Beta-lactamase
HCHLGBMO_01894 4.6e-299 I Protein of unknown function (DUF2974)
HCHLGBMO_01895 1.8e-38 C FMN_bind
HCHLGBMO_01896 3.9e-82
HCHLGBMO_01897 1.8e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HCHLGBMO_01898 6.4e-90 alkD L DNA alkylation repair enzyme
HCHLGBMO_01899 6.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCHLGBMO_01900 1.1e-127 K UTRA domain
HCHLGBMO_01901 1.6e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HCHLGBMO_01902 4.3e-59 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HCHLGBMO_01903 3.2e-11
HCHLGBMO_01904 1.6e-61
HCHLGBMO_01905 1.1e-248 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCHLGBMO_01906 3.2e-71 S Domain of unknown function (DUF3284)
HCHLGBMO_01907 5.4e-302 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCHLGBMO_01908 2.1e-118 gmuR K UTRA
HCHLGBMO_01909 3.7e-223 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCHLGBMO_01910 5.8e-274 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCHLGBMO_01911 9.2e-137 ypbG 2.7.1.2 GK ROK family
HCHLGBMO_01912 4.4e-36 C nitroreductase
HCHLGBMO_01913 5.3e-22 C nitroreductase
HCHLGBMO_01914 1.5e-155 arbx M Glycosyl transferase family 8
HCHLGBMO_01915 4.2e-149 arbV 2.3.1.51 I Acyl-transferase
HCHLGBMO_01917 4.9e-34
HCHLGBMO_01919 1.8e-130 K response regulator
HCHLGBMO_01920 7.5e-91 S Domain of unknown function (DUF4767)
HCHLGBMO_01921 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCHLGBMO_01922 2.2e-151 yitS S Uncharacterised protein, DegV family COG1307
HCHLGBMO_01923 4.6e-100 3.6.1.27 I Acid phosphatase homologues
HCHLGBMO_01924 3.2e-178 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCHLGBMO_01926 1.6e-172 MA20_14895 S Conserved hypothetical protein 698
HCHLGBMO_01927 6.3e-26 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
HCHLGBMO_01928 9.5e-30 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
HCHLGBMO_01929 4.9e-284 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HCHLGBMO_01930 1.2e-30 copZ C Heavy-metal-associated domain
HCHLGBMO_01931 1.6e-78 dps P Belongs to the Dps family
HCHLGBMO_01932 1.9e-86 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HCHLGBMO_01933 2e-129 yobV1 K WYL domain
HCHLGBMO_01934 1.8e-55 S pyridoxamine 5-phosphate
HCHLGBMO_01935 3.8e-84 dps P Belongs to the Dps family
HCHLGBMO_01936 1.7e-151
HCHLGBMO_01938 1.3e-246 ydaM M Glycosyl transferase
HCHLGBMO_01939 3.5e-205 G Glycosyl hydrolases family 8
HCHLGBMO_01940 1.1e-67 L Transposase and inactivated derivatives, IS30 family
HCHLGBMO_01941 2.2e-14 L Transposase and inactivated derivatives, IS30 family
HCHLGBMO_01942 5.8e-13 L Transposase and inactivated derivatives, IS30 family
HCHLGBMO_01943 2.4e-10 L Psort location Cytoplasmic, score
HCHLGBMO_01944 4e-89 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HCHLGBMO_01945 2.8e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HCHLGBMO_01946 2.2e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HCHLGBMO_01947 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HCHLGBMO_01948 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HCHLGBMO_01950 4.8e-138 L An automated process has identified a potential problem with this gene model
HCHLGBMO_01951 2.8e-48 S Peptidase propeptide and YPEB domain
HCHLGBMO_01952 6.5e-169 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HCHLGBMO_01953 7.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HCHLGBMO_01954 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
HCHLGBMO_01955 7.8e-155 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
HCHLGBMO_01956 5e-125 C 2Fe-2S iron-sulfur cluster binding domain
HCHLGBMO_01957 2.8e-140 sufC O FeS assembly ATPase SufC
HCHLGBMO_01958 3.5e-174 sufD O FeS assembly protein SufD
HCHLGBMO_01959 5.3e-178 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCHLGBMO_01960 2.4e-59 nifU C SUF system FeS assembly protein, NifU family
HCHLGBMO_01961 2e-266 sufB O assembly protein SufB
HCHLGBMO_01962 2.4e-45 yitW S Iron-sulfur cluster assembly protein
HCHLGBMO_01963 2.9e-247 mntH P H( )-stimulated, divalent metal cation uptake system
HCHLGBMO_01964 1.5e-245 brnQ U Component of the transport system for branched-chain amino acids
HCHLGBMO_01965 0.0 L Plasmid pRiA4b ORF-3-like protein
HCHLGBMO_01966 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCHLGBMO_01967 2.5e-08 S Protein of unknown function (DUF3021)
HCHLGBMO_01968 2.6e-33 K Bacterial regulatory helix-turn-helix protein, lysR family
HCHLGBMO_01969 9.5e-34 rmaI K Transcriptional regulator
HCHLGBMO_01970 5.4e-171 lmrB EGP Major facilitator Superfamily
HCHLGBMO_01971 7.8e-202 XK27_00915 C Luciferase-like monooxygenase
HCHLGBMO_01972 6.5e-87 K GNAT family
HCHLGBMO_01973 2e-123 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HCHLGBMO_01975 1.5e-36
HCHLGBMO_01976 2.6e-286 P ABC transporter
HCHLGBMO_01977 7.6e-242 V ABC-type multidrug transport system, ATPase and permease components
HCHLGBMO_01978 2.4e-251 yifK E Amino acid permease
HCHLGBMO_01979 3.1e-178 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCHLGBMO_01980 1.2e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCHLGBMO_01981 0.0 aha1 P E1-E2 ATPase
HCHLGBMO_01982 5.8e-177 F DNA/RNA non-specific endonuclease
HCHLGBMO_01983 1e-159 metQ2 P Belongs to the nlpA lipoprotein family
HCHLGBMO_01984 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCHLGBMO_01985 2e-73 metI P ABC transporter permease
HCHLGBMO_01986 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCHLGBMO_01987 1.9e-261 frdC 1.3.5.4 C FAD binding domain
HCHLGBMO_01988 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HCHLGBMO_01989 4.1e-253 pepC 3.4.22.40 E Peptidase C1-like family
HCHLGBMO_01990 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
HCHLGBMO_01991 4.7e-274 P Sodium:sulfate symporter transmembrane region
HCHLGBMO_01992 4.9e-153 ydjP I Alpha/beta hydrolase family
HCHLGBMO_01993 1.4e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HCHLGBMO_01994 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
HCHLGBMO_01995 7.7e-166 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HCHLGBMO_01996 9.2e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HCHLGBMO_01997 7.9e-71 yeaL S Protein of unknown function (DUF441)
HCHLGBMO_01998 1.8e-22
HCHLGBMO_01999 1.2e-144 cbiQ P cobalt transport
HCHLGBMO_02000 0.0 ykoD P ABC transporter, ATP-binding protein
HCHLGBMO_02001 1.5e-95 S UPF0397 protein
HCHLGBMO_02002 2.2e-305 vicK 2.7.13.3 T Histidine kinase
HCHLGBMO_02003 3.3e-258 yycH S YycH protein
HCHLGBMO_02004 3.4e-149 yycI S YycH protein
HCHLGBMO_02005 8.9e-72 vicX 3.1.26.11 S domain protein
HCHLGBMO_02006 2.9e-66 S Domain of unknown function DUF1828
HCHLGBMO_02007 5.5e-09
HCHLGBMO_02008 3.8e-51
HCHLGBMO_02009 2.6e-177 citR K Putative sugar-binding domain
HCHLGBMO_02010 1.9e-250 yjjP S Putative threonine/serine exporter
HCHLGBMO_02012 1.4e-39
HCHLGBMO_02013 2.3e-25 M domain protein
HCHLGBMO_02014 1.1e-84 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCHLGBMO_02015 2.5e-175 prmA J Ribosomal protein L11 methyltransferase
HCHLGBMO_02016 4.2e-36
HCHLGBMO_02017 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCHLGBMO_02018 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCHLGBMO_02019 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HCHLGBMO_02020 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HCHLGBMO_02021 9.8e-222 patA 2.6.1.1 E Aminotransferase
HCHLGBMO_02023 1e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCHLGBMO_02024 4.8e-34 S reductase
HCHLGBMO_02025 4.4e-39 S reductase
HCHLGBMO_02026 2.7e-32 S reductase
HCHLGBMO_02027 8.4e-148 yxeH S hydrolase
HCHLGBMO_02028 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCHLGBMO_02029 1.1e-243 yfnA E Amino Acid
HCHLGBMO_02030 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
HCHLGBMO_02031 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCHLGBMO_02032 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCHLGBMO_02033 7.7e-293 I Acyltransferase
HCHLGBMO_02034 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCHLGBMO_02035 1.9e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCHLGBMO_02036 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
HCHLGBMO_02037 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HCHLGBMO_02038 1.6e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HCHLGBMO_02039 2.3e-23 S Protein of unknown function (DUF2929)
HCHLGBMO_02040 0.0 dnaE 2.7.7.7 L DNA polymerase
HCHLGBMO_02041 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HCHLGBMO_02042 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HCHLGBMO_02043 4.4e-166 cvfB S S1 domain
HCHLGBMO_02044 2.9e-165 xerD D recombinase XerD
HCHLGBMO_02045 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCHLGBMO_02046 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCHLGBMO_02047 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCHLGBMO_02048 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCHLGBMO_02049 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCHLGBMO_02050 2.7e-18 M Lysin motif
HCHLGBMO_02051 5e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HCHLGBMO_02052 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
HCHLGBMO_02053 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HCHLGBMO_02054 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCHLGBMO_02055 3.4e-225 S Tetratricopeptide repeat protein
HCHLGBMO_02056 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCHLGBMO_02057 8.6e-82 yxaM EGP Major facilitator Superfamily
HCHLGBMO_02058 5.2e-69 yxaM EGP Major facilitator Superfamily
HCHLGBMO_02059 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
HCHLGBMO_02060 1e-79 S AAA domain
HCHLGBMO_02061 3.3e-61 3.6.1.55 F NUDIX domain
HCHLGBMO_02062 1.9e-138 2.4.2.3 F Phosphorylase superfamily
HCHLGBMO_02063 9e-144 2.4.2.3 F Phosphorylase superfamily
HCHLGBMO_02064 2.4e-150 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HCHLGBMO_02065 9.7e-65 yagE E amino acid
HCHLGBMO_02066 1.2e-126 yagE E Amino acid permease
HCHLGBMO_02067 9.5e-86 3.4.21.96 S SLAP domain
HCHLGBMO_02068 4.6e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCHLGBMO_02069 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCHLGBMO_02070 1.2e-107 hlyIII S protein, hemolysin III
HCHLGBMO_02071 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
HCHLGBMO_02072 7.1e-36 yozE S Belongs to the UPF0346 family
HCHLGBMO_02073 1.1e-66 yjcE P NhaP-type Na H and K H
HCHLGBMO_02074 9.6e-40 yjcE P Sodium proton antiporter
HCHLGBMO_02075 1.9e-94 yjcE P Sodium proton antiporter
HCHLGBMO_02076 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCHLGBMO_02077 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCHLGBMO_02078 5.8e-152 dprA LU DNA protecting protein DprA
HCHLGBMO_02079 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCHLGBMO_02080 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HCHLGBMO_02081 6.5e-141 xerC D Phage integrase, N-terminal SAM-like domain
HCHLGBMO_02082 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HCHLGBMO_02083 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HCHLGBMO_02084 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
HCHLGBMO_02085 1.1e-86 C Aldo keto reductase
HCHLGBMO_02086 7.1e-63 M LysM domain protein
HCHLGBMO_02087 3.2e-53 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCHLGBMO_02088 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCHLGBMO_02089 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HCHLGBMO_02090 1.4e-115 mmuP E amino acid
HCHLGBMO_02091 1.2e-271 pepV 3.5.1.18 E dipeptidase PepV
HCHLGBMO_02092 1.6e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HCHLGBMO_02093 3.2e-283 E Amino acid permease
HCHLGBMO_02094 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HCHLGBMO_02095 5.1e-245 ynbB 4.4.1.1 P aluminum resistance
HCHLGBMO_02096 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HCHLGBMO_02097 2.2e-36 L PFAM transposase, IS4 family protein
HCHLGBMO_02098 1.4e-126 L PFAM transposase, IS4 family protein
HCHLGBMO_02099 9.9e-82 C Flavodoxin
HCHLGBMO_02100 0.0 uvrA3 L excinuclease ABC, A subunit
HCHLGBMO_02101 6.5e-19 uvrA3 L excinuclease ABC, A subunit
HCHLGBMO_02102 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HCHLGBMO_02103 2.1e-114 3.6.1.27 I Acid phosphatase homologues
HCHLGBMO_02104 1.1e-200 L COG2826 Transposase and inactivated derivatives, IS30 family
HCHLGBMO_02105 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCHLGBMO_02106 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
HCHLGBMO_02107 9.3e-204 pbpX1 V Beta-lactamase
HCHLGBMO_02108 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HCHLGBMO_02109 7.5e-95 S ECF-type riboflavin transporter, S component
HCHLGBMO_02110 1.3e-229 S Putative peptidoglycan binding domain
HCHLGBMO_02111 9e-83 K Acetyltransferase (GNAT) domain
HCHLGBMO_02112 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HCHLGBMO_02113 1.2e-190 yrvN L AAA C-terminal domain
HCHLGBMO_02114 5.7e-65 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCHLGBMO_02115 7.3e-283 treB G phosphotransferase system
HCHLGBMO_02116 8.9e-101 treR K UTRA
HCHLGBMO_02117 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HCHLGBMO_02118 5.7e-18
HCHLGBMO_02119 7.3e-239 G Bacterial extracellular solute-binding protein
HCHLGBMO_02120 3.6e-51 vicX 3.1.26.11 S domain protein
HCHLGBMO_02121 3.3e-151 htrA 3.4.21.107 O serine protease
HCHLGBMO_02122 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCHLGBMO_02123 1.6e-33 G Peptidase_C39 like family
HCHLGBMO_02124 4.4e-163 M NlpC/P60 family
HCHLGBMO_02125 1e-91 G Peptidase_C39 like family
HCHLGBMO_02126 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HCHLGBMO_02127 9.6e-78 P Cobalt transport protein
HCHLGBMO_02128 2.4e-248 cbiO1 S ABC transporter, ATP-binding protein
HCHLGBMO_02129 7.9e-174 K helix_turn_helix, arabinose operon control protein
HCHLGBMO_02130 6.4e-157 htpX O Belongs to the peptidase M48B family
HCHLGBMO_02131 9.7e-95 lemA S LemA family
HCHLGBMO_02132 6e-169 ybiR P Citrate transporter
HCHLGBMO_02134 7.8e-70 S Iron-sulphur cluster biosynthesis
HCHLGBMO_02135 1.7e-211 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HCHLGBMO_02136 7.2e-83 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HCHLGBMO_02137 1.2e-17
HCHLGBMO_02138 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
HCHLGBMO_02139 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
HCHLGBMO_02141 0.0 S SLAP domain
HCHLGBMO_02142 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
HCHLGBMO_02143 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
HCHLGBMO_02144 3.4e-42 S RloB-like protein
HCHLGBMO_02145 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
HCHLGBMO_02146 1.7e-98 3.1.21.3 V Type I restriction modification DNA specificity domain
HCHLGBMO_02147 1.2e-63 S SIR2-like domain
HCHLGBMO_02148 3.2e-10 S Domain of unknown function DUF87
HCHLGBMO_02149 2e-75 S cog cog0433
HCHLGBMO_02150 1.9e-110 F DNA/RNA non-specific endonuclease
HCHLGBMO_02151 2.7e-34 S YSIRK type signal peptide
HCHLGBMO_02153 5.5e-53
HCHLGBMO_02154 2.3e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HCHLGBMO_02155 1.4e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCHLGBMO_02156 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCHLGBMO_02157 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCHLGBMO_02158 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HCHLGBMO_02159 0.0 FbpA K Fibronectin-binding protein
HCHLGBMO_02160 1.1e-66
HCHLGBMO_02161 1.3e-159 degV S EDD domain protein, DegV family
HCHLGBMO_02162 9e-60 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCHLGBMO_02163 3.5e-205 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCHLGBMO_02164 5.4e-203 xerS L Belongs to the 'phage' integrase family
HCHLGBMO_02165 4.1e-67
HCHLGBMO_02166 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
HCHLGBMO_02167 1.5e-211 M Glycosyl hydrolases family 25
HCHLGBMO_02168 2e-39 S Transglycosylase associated protein
HCHLGBMO_02169 4e-57 K Helix-turn-helix domain
HCHLGBMO_02170 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCHLGBMO_02171 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
HCHLGBMO_02172 3.6e-182 K Transcriptional regulator
HCHLGBMO_02173 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCHLGBMO_02174 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCHLGBMO_02175 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCHLGBMO_02176 0.0 snf 2.7.11.1 KL domain protein
HCHLGBMO_02177 2e-35
HCHLGBMO_02179 3.8e-104 pncA Q Isochorismatase family
HCHLGBMO_02180 4.9e-118
HCHLGBMO_02183 3.6e-63
HCHLGBMO_02184 1.4e-34
HCHLGBMO_02185 3.4e-79
HCHLGBMO_02186 1e-242 cpdA S Calcineurin-like phosphoesterase
HCHLGBMO_02187 1.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HCHLGBMO_02188 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCHLGBMO_02189 1e-107 ypsA S Belongs to the UPF0398 family
HCHLGBMO_02190 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCHLGBMO_02191 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HCHLGBMO_02192 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCHLGBMO_02193 1.3e-114 dnaD L DnaD domain protein
HCHLGBMO_02194 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HCHLGBMO_02195 9.2e-89 ypmB S Protein conserved in bacteria
HCHLGBMO_02196 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HCHLGBMO_02197 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HCHLGBMO_02198 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HCHLGBMO_02199 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HCHLGBMO_02200 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HCHLGBMO_02201 6e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HCHLGBMO_02202 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HCHLGBMO_02203 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HCHLGBMO_02204 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HCHLGBMO_02205 9.7e-169
HCHLGBMO_02206 7.5e-143
HCHLGBMO_02207 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HCHLGBMO_02208 1.4e-26
HCHLGBMO_02209 6.7e-145
HCHLGBMO_02210 5.1e-137
HCHLGBMO_02211 4.5e-141
HCHLGBMO_02212 2.8e-123 skfE V ATPases associated with a variety of cellular activities
HCHLGBMO_02213 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
HCHLGBMO_02214 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HCHLGBMO_02215 3.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCHLGBMO_02216 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HCHLGBMO_02217 4.8e-81 mutT 3.6.1.55 F NUDIX domain
HCHLGBMO_02218 1.4e-127 S Peptidase family M23
HCHLGBMO_02219 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCHLGBMO_02220 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCHLGBMO_02221 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HCHLGBMO_02222 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HCHLGBMO_02223 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
HCHLGBMO_02224 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCHLGBMO_02225 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCHLGBMO_02226 2.5e-175 phoH T phosphate starvation-inducible protein PhoH
HCHLGBMO_02227 3.5e-71 yqeY S YqeY-like protein
HCHLGBMO_02228 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HCHLGBMO_02229 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCHLGBMO_02230 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
HCHLGBMO_02231 2e-219 L Transposase
HCHLGBMO_02232 4e-40 S CRISPR-associated protein (Cas_Csn2)
HCHLGBMO_02233 8.3e-40 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCHLGBMO_02234 3e-130 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCHLGBMO_02235 1.1e-08
HCHLGBMO_02241 1e-83 ps308 K AntA/AntB antirepressor
HCHLGBMO_02246 1.1e-24 S HNH endonuclease
HCHLGBMO_02247 1.3e-09
HCHLGBMO_02250 1.1e-20 L Psort location Cytoplasmic, score
HCHLGBMO_02258 2.3e-10 K Helix-turn-helix XRE-family like proteins
HCHLGBMO_02259 6.2e-74 3.4.21.88 K Peptidase S24-like
HCHLGBMO_02260 2.5e-30 S Hypothetical protein (DUF2513)
HCHLGBMO_02263 1.6e-180 V Abi-like protein
HCHLGBMO_02264 3.1e-122 L Belongs to the 'phage' integrase family
HCHLGBMO_02265 2.3e-08 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCHLGBMO_02267 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCHLGBMO_02268 2.5e-118
HCHLGBMO_02269 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCHLGBMO_02270 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HCHLGBMO_02271 2.6e-280 thrC 4.2.3.1 E Threonine synthase
HCHLGBMO_02272 8.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HCHLGBMO_02273 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
HCHLGBMO_02274 0.0 L PLD-like domain
HCHLGBMO_02275 4.8e-42 S SnoaL-like domain
HCHLGBMO_02276 5.4e-53 hipB K sequence-specific DNA binding
HCHLGBMO_02277 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
HCHLGBMO_02278 3.4e-27
HCHLGBMO_02279 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
HCHLGBMO_02280 8.9e-276 V ABC-type multidrug transport system, ATPase and permease components

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)