ORF_ID e_value Gene_name EC_number CAZy COGs Description
IHGKNBMB_00001 2.6e-177 S Aldo keto reductase
IHGKNBMB_00002 9.9e-75 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
IHGKNBMB_00003 0.0 L Helicase C-terminal domain protein
IHGKNBMB_00005 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
IHGKNBMB_00006 2.1e-207 carA 6.3.5.5 F Belongs to the CarA family
IHGKNBMB_00007 3.8e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IHGKNBMB_00008 2.9e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IHGKNBMB_00009 1.5e-65 esbA S Family of unknown function (DUF5322)
IHGKNBMB_00010 4.4e-70 rnhA 3.1.26.4 L Ribonuclease HI
IHGKNBMB_00011 1.9e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IHGKNBMB_00013 4.1e-13
IHGKNBMB_00023 2.4e-07 3.5.1.28 M Cell wall hydrolase
IHGKNBMB_00029 1.6e-26
IHGKNBMB_00031 1.2e-26
IHGKNBMB_00032 5.5e-33 S Psort location Cytoplasmic, score 8.87
IHGKNBMB_00033 2.3e-43
IHGKNBMB_00034 1.5e-16 S Psort location Cytoplasmic, score 8.87
IHGKNBMB_00035 1.1e-21 S Psort location Cytoplasmic, score 8.87
IHGKNBMB_00036 0.0 S DNA polymerase type-B family
IHGKNBMB_00037 2.9e-11 S Ferredoxin thioredoxin reductase catalytic beta chain
IHGKNBMB_00038 5.1e-58 S phosphatase activity
IHGKNBMB_00039 1.1e-17
IHGKNBMB_00041 8.5e-152 KL Helicase conserved C-terminal domain
IHGKNBMB_00046 2.9e-40 comEB 3.5.4.12 F deaminase
IHGKNBMB_00052 1.9e-28 2.7.1.24 H dephospho-CoA kinase activity
IHGKNBMB_00057 2.3e-32 cof S phosphatase activity
IHGKNBMB_00063 1e-259 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IHGKNBMB_00064 4e-148 f42a O Band 7 protein
IHGKNBMB_00065 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
IHGKNBMB_00066 2.4e-130 lytT K response regulator receiver
IHGKNBMB_00067 1.9e-66 lrgA S LrgA family
IHGKNBMB_00068 2.6e-124 lrgB M LrgB-like family
IHGKNBMB_00069 1.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IHGKNBMB_00070 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IHGKNBMB_00071 4.2e-189 galR K Periplasmic binding protein-like domain
IHGKNBMB_00072 0.0 rafA 3.2.1.22 G alpha-galactosidase
IHGKNBMB_00073 3.8e-87 S Protein of unknown function (DUF1440)
IHGKNBMB_00074 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IHGKNBMB_00075 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IHGKNBMB_00076 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IHGKNBMB_00077 5.7e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IHGKNBMB_00078 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IHGKNBMB_00079 2.9e-85 ypmB S Protein conserved in bacteria
IHGKNBMB_00080 3e-125 dnaD L DnaD domain protein
IHGKNBMB_00081 2e-161 EG EamA-like transporter family
IHGKNBMB_00082 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IHGKNBMB_00083 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IHGKNBMB_00084 1.6e-105 ypsA S Belongs to the UPF0398 family
IHGKNBMB_00085 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IHGKNBMB_00086 3.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IHGKNBMB_00087 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IHGKNBMB_00088 1.8e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IHGKNBMB_00089 4.2e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IHGKNBMB_00091 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHGKNBMB_00092 2.4e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IHGKNBMB_00093 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IHGKNBMB_00094 1.3e-35 ynzC S UPF0291 protein
IHGKNBMB_00095 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
IHGKNBMB_00096 4.6e-117 plsC 2.3.1.51 I Acyltransferase
IHGKNBMB_00097 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
IHGKNBMB_00098 5.4e-49 yazA L GIY-YIG catalytic domain protein
IHGKNBMB_00099 4.4e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHGKNBMB_00100 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
IHGKNBMB_00101 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IHGKNBMB_00102 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IHGKNBMB_00103 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IHGKNBMB_00104 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IHGKNBMB_00105 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
IHGKNBMB_00106 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IHGKNBMB_00107 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IHGKNBMB_00108 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHGKNBMB_00109 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
IHGKNBMB_00110 1e-215 nusA K Participates in both transcription termination and antitermination
IHGKNBMB_00111 1e-44 ylxR K Protein of unknown function (DUF448)
IHGKNBMB_00112 4.5e-49 ylxQ J ribosomal protein
IHGKNBMB_00113 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IHGKNBMB_00114 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IHGKNBMB_00115 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IHGKNBMB_00116 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IHGKNBMB_00117 1.2e-152 EG EamA-like transporter family
IHGKNBMB_00118 2.5e-118 L Integrase
IHGKNBMB_00119 1.4e-158 rssA S Phospholipase, patatin family
IHGKNBMB_00120 9.9e-242 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
IHGKNBMB_00121 1.6e-52 azlD S branched-chain amino acid
IHGKNBMB_00122 3.7e-136 azlC E AzlC protein
IHGKNBMB_00123 6.5e-199 hpk31 2.7.13.3 T Histidine kinase
IHGKNBMB_00124 1.2e-123 K response regulator
IHGKNBMB_00125 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IHGKNBMB_00126 9.5e-172 deoR K sugar-binding domain protein
IHGKNBMB_00127 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IHGKNBMB_00128 2.7e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
IHGKNBMB_00129 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IHGKNBMB_00130 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IHGKNBMB_00131 7.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
IHGKNBMB_00132 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IHGKNBMB_00133 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
IHGKNBMB_00134 1.7e-154 spo0J K Belongs to the ParB family
IHGKNBMB_00135 3.9e-139 soj D Sporulation initiation inhibitor
IHGKNBMB_00136 4.3e-151 noc K Belongs to the ParB family
IHGKNBMB_00137 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IHGKNBMB_00138 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
IHGKNBMB_00139 5.6e-169 rihC 3.2.2.1 F Nucleoside
IHGKNBMB_00140 2.3e-218 nupG F Nucleoside transporter
IHGKNBMB_00141 3.2e-221 cycA E Amino acid permease
IHGKNBMB_00143 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IHGKNBMB_00144 1.2e-264 glnP P ABC transporter
IHGKNBMB_00145 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IHGKNBMB_00151 1.6e-42
IHGKNBMB_00152 4.5e-112 S CAAX protease self-immunity
IHGKNBMB_00153 2.1e-32
IHGKNBMB_00154 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHGKNBMB_00155 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
IHGKNBMB_00156 3.8e-113
IHGKNBMB_00157 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
IHGKNBMB_00158 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IHGKNBMB_00159 1.2e-85 uspA T Belongs to the universal stress protein A family
IHGKNBMB_00160 4.3e-277 pepV 3.5.1.18 E dipeptidase PepV
IHGKNBMB_00161 6.5e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IHGKNBMB_00162 4.1e-303 ytgP S Polysaccharide biosynthesis protein
IHGKNBMB_00163 4.9e-41
IHGKNBMB_00164 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IHGKNBMB_00165 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IHGKNBMB_00166 9.6e-92 tag 3.2.2.20 L glycosylase
IHGKNBMB_00167 1.5e-253 EGP Major facilitator Superfamily
IHGKNBMB_00168 4.3e-85 perR P Belongs to the Fur family
IHGKNBMB_00169 4.8e-233 cycA E Amino acid permease
IHGKNBMB_00170 2.8e-102 V VanZ like family
IHGKNBMB_00171 1e-23
IHGKNBMB_00172 7.7e-86 S Short repeat of unknown function (DUF308)
IHGKNBMB_00173 2.9e-78 S Psort location Cytoplasmic, score
IHGKNBMB_00174 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
IHGKNBMB_00175 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
IHGKNBMB_00176 8.1e-154 yeaE S Aldo keto
IHGKNBMB_00177 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IHGKNBMB_00178 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IHGKNBMB_00179 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IHGKNBMB_00180 4.7e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHGKNBMB_00181 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IHGKNBMB_00182 1.4e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IHGKNBMB_00183 7.1e-150
IHGKNBMB_00184 4e-17 3.2.1.14 GH18
IHGKNBMB_00185 1.5e-82 zur P Belongs to the Fur family
IHGKNBMB_00186 1.9e-101 gmk2 2.7.4.8 F Guanylate kinase
IHGKNBMB_00187 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IHGKNBMB_00188 3e-254 yfnA E Amino Acid
IHGKNBMB_00189 7.2e-234 EGP Sugar (and other) transporter
IHGKNBMB_00190 8.1e-230
IHGKNBMB_00191 4.3e-208 potD P ABC transporter
IHGKNBMB_00192 4.9e-140 potC P ABC transporter permease
IHGKNBMB_00193 4.5e-146 potB P ABC transporter permease
IHGKNBMB_00194 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IHGKNBMB_00195 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IHGKNBMB_00196 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IHGKNBMB_00197 0.0 pacL 3.6.3.8 P P-type ATPase
IHGKNBMB_00198 3.4e-85 dps P Belongs to the Dps family
IHGKNBMB_00199 2.8e-255 yagE E amino acid
IHGKNBMB_00200 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IHGKNBMB_00201 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IHGKNBMB_00202 2.5e-127 L Helix-turn-helix domain
IHGKNBMB_00203 6.7e-150 L hmm pf00665
IHGKNBMB_00204 1.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
IHGKNBMB_00205 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
IHGKNBMB_00206 2e-22
IHGKNBMB_00207 4.4e-34 S Protein of unknown function (DUF2800)
IHGKNBMB_00208 8.9e-218 K Bacterial regulatory proteins, luxR family
IHGKNBMB_00209 9.6e-20
IHGKNBMB_00210 2.9e-19
IHGKNBMB_00211 1.5e-40
IHGKNBMB_00212 9.5e-20 S Psort location Cytoplasmic, score 8.87
IHGKNBMB_00214 6.1e-281 S Phage Terminase
IHGKNBMB_00215 1.3e-56
IHGKNBMB_00216 5.1e-27
IHGKNBMB_00217 7.3e-145 S Phage portal protein
IHGKNBMB_00218 1.4e-118 S peptidase activity
IHGKNBMB_00219 1.8e-25
IHGKNBMB_00220 2.6e-22
IHGKNBMB_00221 1.5e-56
IHGKNBMB_00223 1.9e-26
IHGKNBMB_00224 2.2e-51
IHGKNBMB_00225 5.8e-33 S Bacteriophage HK97-gp10, putative tail-component
IHGKNBMB_00226 2.4e-93 S phage tail tape measure protein
IHGKNBMB_00228 2.7e-73 S Alpha beta hydrolase
IHGKNBMB_00229 1.7e-207 gldA 1.1.1.6 C dehydrogenase
IHGKNBMB_00230 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IHGKNBMB_00231 1.3e-41
IHGKNBMB_00232 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
IHGKNBMB_00233 1.1e-27 S C4-dicarboxylate anaerobic carrier
IHGKNBMB_00234 1.8e-240 S C4-dicarboxylate anaerobic carrier
IHGKNBMB_00235 1.8e-251 nhaC C Na H antiporter NhaC
IHGKNBMB_00236 1.6e-241 pbuX F xanthine permease
IHGKNBMB_00237 1.4e-283 pipD E Dipeptidase
IHGKNBMB_00238 1.6e-305 L Transposase
IHGKNBMB_00239 2.2e-168 corA P CorA-like Mg2+ transporter protein
IHGKNBMB_00240 4.5e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IHGKNBMB_00241 2.3e-131 terC P membrane
IHGKNBMB_00242 2.1e-54 trxA O Belongs to the thioredoxin family
IHGKNBMB_00243 1.6e-236 mepA V MATE efflux family protein
IHGKNBMB_00244 4.2e-55 M Leucine-rich repeat (LRR) protein
IHGKNBMB_00245 6.8e-56 K Transcriptional regulator, ArsR family
IHGKNBMB_00246 2.5e-90 P Cadmium resistance transporter
IHGKNBMB_00247 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
IHGKNBMB_00248 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IHGKNBMB_00249 2.1e-35 ABC-SBP S ABC transporter
IHGKNBMB_00250 2.5e-36
IHGKNBMB_00251 5.4e-253 pgaC GT2 M Glycosyl transferase
IHGKNBMB_00252 3.7e-140 T EAL domain
IHGKNBMB_00253 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
IHGKNBMB_00254 1.1e-64 yneR
IHGKNBMB_00255 1.2e-112 GM NAD(P)H-binding
IHGKNBMB_00256 6.1e-88 S membrane
IHGKNBMB_00257 1e-73 S membrane
IHGKNBMB_00258 1.8e-104 K Transcriptional regulator C-terminal region
IHGKNBMB_00259 7.6e-163 akr5f 1.1.1.346 S reductase
IHGKNBMB_00260 4.3e-40 K Transcriptional regulator
IHGKNBMB_00261 4.3e-59 K Transcriptional regulator
IHGKNBMB_00262 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
IHGKNBMB_00263 2.3e-155 ypuA S Protein of unknown function (DUF1002)
IHGKNBMB_00264 4.7e-66 GM NAD(P)H-binding
IHGKNBMB_00265 3.3e-92 padR K Virulence activator alpha C-term
IHGKNBMB_00266 2.3e-93 padC Q Phenolic acid decarboxylase
IHGKNBMB_00267 2e-152 S Alpha beta hydrolase
IHGKNBMB_00268 9.4e-32 S thiolester hydrolase activity
IHGKNBMB_00269 6.3e-88 lacA S transferase hexapeptide repeat
IHGKNBMB_00270 5.6e-158 K Transcriptional regulator
IHGKNBMB_00271 2.7e-85 C Flavodoxin
IHGKNBMB_00272 7.3e-166 S Oxidoreductase, aldo keto reductase family protein
IHGKNBMB_00273 8.2e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
IHGKNBMB_00274 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IHGKNBMB_00275 5.3e-83 K Bacterial regulatory proteins, tetR family
IHGKNBMB_00276 4.3e-55 yphJ 4.1.1.44 S decarboxylase
IHGKNBMB_00277 1.7e-76 P FAD-binding domain
IHGKNBMB_00278 4.7e-109 S Peptidase propeptide and YPEB domain
IHGKNBMB_00279 9.9e-239 T GHKL domain
IHGKNBMB_00280 7.3e-121 T Transcriptional regulatory protein, C terminal
IHGKNBMB_00281 3.9e-27 mleP3 S Membrane transport protein
IHGKNBMB_00285 8.6e-35 M hydrolase, family 25
IHGKNBMB_00289 2.5e-29
IHGKNBMB_00292 2.9e-24
IHGKNBMB_00294 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IHGKNBMB_00295 2.4e-65 K HxlR-like helix-turn-helix
IHGKNBMB_00296 8.5e-54 S macrophage migration inhibitory factor
IHGKNBMB_00297 1.1e-50 yqiG C Oxidoreductase
IHGKNBMB_00298 7.8e-20 yqiG C Oxidoreductase
IHGKNBMB_00299 3.7e-91 yqiG C Oxidoreductase
IHGKNBMB_00301 3.7e-19
IHGKNBMB_00302 5e-263 dtpT U amino acid peptide transporter
IHGKNBMB_00303 1.4e-158 yjjH S Calcineurin-like phosphoesterase
IHGKNBMB_00306 5.5e-110
IHGKNBMB_00307 2.8e-252 EGP Major facilitator Superfamily
IHGKNBMB_00308 9.5e-300 aspT P Predicted Permease Membrane Region
IHGKNBMB_00309 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IHGKNBMB_00310 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
IHGKNBMB_00311 1.7e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IHGKNBMB_00312 5.1e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IHGKNBMB_00313 0.0 yhgF K Tex-like protein N-terminal domain protein
IHGKNBMB_00314 1.9e-85 ydcK S Belongs to the SprT family
IHGKNBMB_00316 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IHGKNBMB_00317 1.3e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IHGKNBMB_00318 0.0 S Bacterial membrane protein, YfhO
IHGKNBMB_00319 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IHGKNBMB_00320 3.1e-169 I alpha/beta hydrolase fold
IHGKNBMB_00321 9.4e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IHGKNBMB_00322 2.4e-119 tcyB E ABC transporter
IHGKNBMB_00323 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IHGKNBMB_00324 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IHGKNBMB_00325 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
IHGKNBMB_00326 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IHGKNBMB_00327 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
IHGKNBMB_00328 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IHGKNBMB_00329 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IHGKNBMB_00330 1.7e-207 yacL S domain protein
IHGKNBMB_00331 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IHGKNBMB_00332 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IHGKNBMB_00333 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHGKNBMB_00334 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IHGKNBMB_00335 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IHGKNBMB_00336 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
IHGKNBMB_00337 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IHGKNBMB_00338 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IHGKNBMB_00339 1.3e-226 aadAT EK Aminotransferase, class I
IHGKNBMB_00341 9.6e-247 M Glycosyl transferase family group 2
IHGKNBMB_00342 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IHGKNBMB_00343 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IHGKNBMB_00344 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IHGKNBMB_00345 1.5e-48
IHGKNBMB_00347 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IHGKNBMB_00348 4e-56 K transcriptional regulator PadR family
IHGKNBMB_00349 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
IHGKNBMB_00350 6.4e-126 S Putative adhesin
IHGKNBMB_00351 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IHGKNBMB_00352 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHGKNBMB_00353 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHGKNBMB_00354 3.4e-35 nrdH O Glutaredoxin
IHGKNBMB_00355 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IHGKNBMB_00356 6.2e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHGKNBMB_00357 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IHGKNBMB_00358 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IHGKNBMB_00359 9.7e-39 S Protein of unknown function (DUF2508)
IHGKNBMB_00360 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IHGKNBMB_00361 7.6e-52 yaaQ S Cyclic-di-AMP receptor
IHGKNBMB_00362 8.2e-185 holB 2.7.7.7 L DNA polymerase III
IHGKNBMB_00363 5.9e-58 yabA L Involved in initiation control of chromosome replication
IHGKNBMB_00364 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IHGKNBMB_00365 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
IHGKNBMB_00366 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IHGKNBMB_00367 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IHGKNBMB_00368 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IHGKNBMB_00369 3e-203 coiA 3.6.4.12 S Competence protein
IHGKNBMB_00370 9.2e-264 pipD E Dipeptidase
IHGKNBMB_00371 4.7e-114 yjbH Q Thioredoxin
IHGKNBMB_00372 1.2e-160 EG EamA-like transporter family
IHGKNBMB_00373 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IHGKNBMB_00374 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IHGKNBMB_00375 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IHGKNBMB_00376 0.0 copA 3.6.3.54 P P-type ATPase
IHGKNBMB_00377 1.7e-84
IHGKNBMB_00379 9.8e-166 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IHGKNBMB_00380 1.2e-95 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
IHGKNBMB_00381 2.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IHGKNBMB_00382 3.9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IHGKNBMB_00383 4.7e-102 T Ion transport 2 domain protein
IHGKNBMB_00384 0.0 S Bacterial membrane protein YfhO
IHGKNBMB_00385 5e-202 G Transporter, major facilitator family protein
IHGKNBMB_00386 5.4e-109 yvrI K sigma factor activity
IHGKNBMB_00387 3.5e-64 ydiI Q Thioesterase superfamily
IHGKNBMB_00388 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IHGKNBMB_00389 5.5e-272 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IHGKNBMB_00390 5.5e-19
IHGKNBMB_00391 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IHGKNBMB_00392 4.2e-32 feoA P FeoA domain
IHGKNBMB_00393 6.5e-145 sufC O FeS assembly ATPase SufC
IHGKNBMB_00394 1.1e-237 sufD O FeS assembly protein SufD
IHGKNBMB_00395 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHGKNBMB_00396 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
IHGKNBMB_00397 1.6e-271 sufB O assembly protein SufB
IHGKNBMB_00398 2.8e-57 yitW S Iron-sulfur cluster assembly protein
IHGKNBMB_00399 2.7e-160 hipB K Helix-turn-helix
IHGKNBMB_00400 9.8e-115 nreC K PFAM regulatory protein LuxR
IHGKNBMB_00401 9.2e-39 S Cytochrome B5
IHGKNBMB_00402 4.8e-119 yitU 3.1.3.104 S hydrolase
IHGKNBMB_00403 7.9e-158 amtB P ammonium transporter
IHGKNBMB_00404 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IHGKNBMB_00406 1.3e-46
IHGKNBMB_00407 3.2e-96 S PFAM Archaeal ATPase
IHGKNBMB_00408 7.6e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IHGKNBMB_00409 0.0 sbcC L Putative exonuclease SbcCD, C subunit
IHGKNBMB_00410 3.6e-143 L Transposase
IHGKNBMB_00411 1e-51
IHGKNBMB_00412 4.8e-153 L Belongs to the 'phage' integrase family
IHGKNBMB_00415 0.0 snf 2.7.11.1 KL domain protein
IHGKNBMB_00416 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IHGKNBMB_00417 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
IHGKNBMB_00418 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IHGKNBMB_00419 7.4e-141 ymfM S Helix-turn-helix domain
IHGKNBMB_00420 3.2e-250 ymfH S Peptidase M16
IHGKNBMB_00421 1.6e-230 ymfF S Peptidase M16 inactive domain protein
IHGKNBMB_00422 2.6e-160 aatB ET ABC transporter substrate-binding protein
IHGKNBMB_00423 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IHGKNBMB_00424 3.2e-102 glnP P ABC transporter permease
IHGKNBMB_00425 1.2e-91 mreD M rod shape-determining protein MreD
IHGKNBMB_00426 2.2e-151 mreC M Involved in formation and maintenance of cell shape
IHGKNBMB_00427 1.7e-179 mreB D cell shape determining protein MreB
IHGKNBMB_00428 6.8e-121 radC L DNA repair protein
IHGKNBMB_00429 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IHGKNBMB_00430 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
IHGKNBMB_00431 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IHGKNBMB_00432 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IHGKNBMB_00433 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IHGKNBMB_00434 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
IHGKNBMB_00435 1.8e-300 xylB 2.7.1.17 G Belongs to the FGGY kinase family
IHGKNBMB_00436 8.1e-154 KT YcbB domain
IHGKNBMB_00437 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IHGKNBMB_00438 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
IHGKNBMB_00439 2e-91 K Acetyltransferase (GNAT) family
IHGKNBMB_00440 3.1e-21
IHGKNBMB_00441 1.1e-119 ybhL S Belongs to the BI1 family
IHGKNBMB_00442 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
IHGKNBMB_00443 9.3e-197 S Protein of unknown function (DUF3114)
IHGKNBMB_00444 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IHGKNBMB_00445 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IHGKNBMB_00446 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
IHGKNBMB_00447 9.1e-62 S Domain of unknown function (DUF4828)
IHGKNBMB_00448 4.5e-191 mocA S Oxidoreductase
IHGKNBMB_00449 8.5e-227 yfmL L DEAD DEAH box helicase
IHGKNBMB_00451 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IHGKNBMB_00452 9.3e-56
IHGKNBMB_00453 2.3e-67 gtcA S Teichoic acid glycosylation protein
IHGKNBMB_00454 6.1e-79 fld C Flavodoxin
IHGKNBMB_00455 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
IHGKNBMB_00456 1.7e-220 arcT 2.6.1.1 E Aminotransferase
IHGKNBMB_00457 3.6e-255 E Arginine ornithine antiporter
IHGKNBMB_00458 1.1e-281 yjeM E Amino Acid
IHGKNBMB_00459 3.2e-153 yihY S Belongs to the UPF0761 family
IHGKNBMB_00460 6.6e-34 S Protein of unknown function (DUF2922)
IHGKNBMB_00461 4.9e-31
IHGKNBMB_00462 7.4e-125 recX 2.4.1.337 GT4 S Regulatory protein RecX
IHGKNBMB_00463 3.3e-146 cps1D M Domain of unknown function (DUF4422)
IHGKNBMB_00464 4.2e-111 3.6.1.13, 3.6.1.55 F NUDIX domain
IHGKNBMB_00465 4e-230 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IHGKNBMB_00466 5.6e-79 pncA Q Isochorismatase family
IHGKNBMB_00467 7.9e-61 pldB 3.1.1.5 I Serine aminopeptidase, S33
IHGKNBMB_00469 2.7e-26 K TRANSCRIPTIONal
IHGKNBMB_00470 2.5e-209 yfeO P Voltage gated chloride channel
IHGKNBMB_00471 5.3e-226 sptS 2.7.13.3 T Histidine kinase
IHGKNBMB_00472 3.3e-118 K response regulator
IHGKNBMB_00473 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
IHGKNBMB_00474 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IHGKNBMB_00475 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IHGKNBMB_00476 1.1e-256 malT G Major Facilitator
IHGKNBMB_00477 3e-49
IHGKNBMB_00478 5.6e-150 E IrrE N-terminal-like domain
IHGKNBMB_00479 4e-119 K Peptidase S24-like
IHGKNBMB_00480 6.8e-222 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHGKNBMB_00481 1.7e-29
IHGKNBMB_00482 1.3e-29
IHGKNBMB_00483 6.1e-54 trxA O Belongs to the thioredoxin family
IHGKNBMB_00484 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IHGKNBMB_00485 1e-85 cvpA S Colicin V production protein
IHGKNBMB_00486 6.1e-48 yrzB S Belongs to the UPF0473 family
IHGKNBMB_00487 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IHGKNBMB_00488 4.1e-43 yrzL S Belongs to the UPF0297 family
IHGKNBMB_00489 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IHGKNBMB_00490 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IHGKNBMB_00491 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IHGKNBMB_00492 2.8e-31 yajC U Preprotein translocase
IHGKNBMB_00493 2.6e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IHGKNBMB_00494 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IHGKNBMB_00495 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IHGKNBMB_00496 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IHGKNBMB_00497 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IHGKNBMB_00498 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
IHGKNBMB_00499 9.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
IHGKNBMB_00500 2e-180 galR K Transcriptional regulator
IHGKNBMB_00501 7.6e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IHGKNBMB_00502 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IHGKNBMB_00503 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
IHGKNBMB_00504 4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
IHGKNBMB_00505 4.8e-93 yxkA S Phosphatidylethanolamine-binding protein
IHGKNBMB_00506 9.1e-36
IHGKNBMB_00507 2.6e-52
IHGKNBMB_00508 2.3e-204
IHGKNBMB_00509 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IHGKNBMB_00510 8.9e-136 pnuC H nicotinamide mononucleotide transporter
IHGKNBMB_00511 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
IHGKNBMB_00512 3.2e-124 K response regulator
IHGKNBMB_00513 1.3e-179 T PhoQ Sensor
IHGKNBMB_00514 2.6e-135 macB2 V ABC transporter, ATP-binding protein
IHGKNBMB_00515 0.0 ysaB V FtsX-like permease family
IHGKNBMB_00516 4.1e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IHGKNBMB_00517 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IHGKNBMB_00518 5.1e-173 2.7.7.65 T GGDEF domain
IHGKNBMB_00519 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
IHGKNBMB_00520 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IHGKNBMB_00521 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
IHGKNBMB_00522 2e-92 folT S ECF transporter, substrate-specific component
IHGKNBMB_00523 0.0 pepN 3.4.11.2 E aminopeptidase
IHGKNBMB_00524 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
IHGKNBMB_00525 9.8e-255 pepC 3.4.22.40 E aminopeptidase
IHGKNBMB_00526 6.5e-210 EGP Major facilitator Superfamily
IHGKNBMB_00527 1.8e-229
IHGKNBMB_00528 5.5e-26 K Transcriptional regulator, HxlR family
IHGKNBMB_00529 1.6e-43 K Transcriptional regulator, HxlR family
IHGKNBMB_00530 1.4e-107 XK27_02070 S Nitroreductase family
IHGKNBMB_00531 2.5e-52 hxlR K Transcriptional regulator, HxlR family
IHGKNBMB_00532 3e-119 GM NmrA-like family
IHGKNBMB_00533 1.7e-70 elaA S Gnat family
IHGKNBMB_00534 1.8e-39 S Cytochrome B5
IHGKNBMB_00535 5.4e-09 S Cytochrome B5
IHGKNBMB_00536 7.8e-41 S Cytochrome B5
IHGKNBMB_00537 6.7e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
IHGKNBMB_00539 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IHGKNBMB_00540 1.3e-96 yslB S Protein of unknown function (DUF2507)
IHGKNBMB_00541 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IHGKNBMB_00542 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IHGKNBMB_00543 4.4e-94 S Phosphoesterase
IHGKNBMB_00544 3.6e-76 ykuL S (CBS) domain
IHGKNBMB_00545 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
IHGKNBMB_00546 3.4e-147 ykuT M mechanosensitive ion channel
IHGKNBMB_00547 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IHGKNBMB_00548 3.5e-26
IHGKNBMB_00549 4.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IHGKNBMB_00550 2.9e-182 ccpA K catabolite control protein A
IHGKNBMB_00551 1.9e-134
IHGKNBMB_00552 3.5e-132 yebC K Transcriptional regulatory protein
IHGKNBMB_00553 2.6e-180 comGA NU Type II IV secretion system protein
IHGKNBMB_00554 9.5e-181 comGB NU type II secretion system
IHGKNBMB_00555 7.1e-47 comGC U competence protein ComGC
IHGKNBMB_00556 8.3e-78 NU general secretion pathway protein
IHGKNBMB_00557 2.7e-40
IHGKNBMB_00558 6.3e-70
IHGKNBMB_00560 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
IHGKNBMB_00561 2.1e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IHGKNBMB_00562 2.2e-113 S Calcineurin-like phosphoesterase
IHGKNBMB_00563 1.3e-93 yutD S Protein of unknown function (DUF1027)
IHGKNBMB_00564 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IHGKNBMB_00565 2.4e-105 S Protein of unknown function (DUF1461)
IHGKNBMB_00566 5.5e-110 dedA S SNARE-like domain protein
IHGKNBMB_00567 3.5e-21 M domain protein
IHGKNBMB_00568 1.1e-53 XK27_01125 L IS66 Orf2 like protein
IHGKNBMB_00569 7.1e-184 L Transposase IS66 family
IHGKNBMB_00570 5.7e-83 gadC E Contains amino acid permease domain
IHGKNBMB_00571 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IHGKNBMB_00572 0.0 yjbQ P TrkA C-terminal domain protein
IHGKNBMB_00573 3.2e-162 MU head morphogenesis protein, SPP1 gp7 family
IHGKNBMB_00574 1.5e-262 S Phage portal protein, SPP1 family
IHGKNBMB_00575 3.7e-135 L Phage terminase, large subunit
IHGKNBMB_00576 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IHGKNBMB_00577 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IHGKNBMB_00578 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
IHGKNBMB_00579 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IHGKNBMB_00580 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IHGKNBMB_00581 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IHGKNBMB_00582 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IHGKNBMB_00583 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IHGKNBMB_00584 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IHGKNBMB_00585 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
IHGKNBMB_00586 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IHGKNBMB_00587 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IHGKNBMB_00588 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IHGKNBMB_00589 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IHGKNBMB_00590 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IHGKNBMB_00591 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IHGKNBMB_00592 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IHGKNBMB_00593 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IHGKNBMB_00594 2.9e-24 rpmD J Ribosomal protein L30
IHGKNBMB_00595 8.9e-64 rplO J Binds to the 23S rRNA
IHGKNBMB_00596 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IHGKNBMB_00597 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IHGKNBMB_00598 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IHGKNBMB_00599 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IHGKNBMB_00600 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IHGKNBMB_00601 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IHGKNBMB_00602 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHGKNBMB_00603 1.1e-62 rplQ J Ribosomal protein L17
IHGKNBMB_00604 3e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHGKNBMB_00605 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHGKNBMB_00606 5.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHGKNBMB_00607 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IHGKNBMB_00608 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IHGKNBMB_00609 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IHGKNBMB_00610 4.5e-75
IHGKNBMB_00612 2e-48
IHGKNBMB_00613 5.7e-34
IHGKNBMB_00614 8.6e-159 pstS P Phosphate
IHGKNBMB_00615 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
IHGKNBMB_00616 5.5e-153 pstA P Phosphate transport system permease protein PstA
IHGKNBMB_00617 2e-135 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IHGKNBMB_00618 7.9e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
IHGKNBMB_00619 1.8e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
IHGKNBMB_00620 2.2e-72
IHGKNBMB_00621 6.2e-76 K Transcriptional regulator, TetR family
IHGKNBMB_00622 4.3e-13 K Transcriptional regulator, TetR family
IHGKNBMB_00624 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IHGKNBMB_00625 3e-86
IHGKNBMB_00626 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IHGKNBMB_00627 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IHGKNBMB_00628 4.2e-261 nox C NADH oxidase
IHGKNBMB_00629 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
IHGKNBMB_00630 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
IHGKNBMB_00631 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
IHGKNBMB_00632 3.8e-167 yvgN C Aldo keto reductase
IHGKNBMB_00633 6.6e-136 puuD S peptidase C26
IHGKNBMB_00634 1.7e-128 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IHGKNBMB_00635 4.4e-129 V ABC transporter
IHGKNBMB_00636 5.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHGKNBMB_00637 2.3e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IHGKNBMB_00638 8.6e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHGKNBMB_00639 3e-147 E Glyoxalase-like domain
IHGKNBMB_00640 1.9e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
IHGKNBMB_00641 2.9e-96 S reductase
IHGKNBMB_00643 1e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IHGKNBMB_00644 4.7e-177 ABC-SBP S ABC transporter
IHGKNBMB_00645 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
IHGKNBMB_00646 9.6e-215 htrA 3.4.21.107 O serine protease
IHGKNBMB_00647 4.5e-154 vicX 3.1.26.11 S domain protein
IHGKNBMB_00648 2.7e-149 yycI S YycH protein
IHGKNBMB_00649 2.1e-246 yycH S YycH protein
IHGKNBMB_00650 0.0 vicK 2.7.13.3 T Histidine kinase
IHGKNBMB_00651 6.8e-130 K response regulator
IHGKNBMB_00653 1.5e-77 S Flavodoxin
IHGKNBMB_00654 3.7e-64 moaE 2.8.1.12 H MoaE protein
IHGKNBMB_00655 4.9e-35 moaD 2.8.1.12 H ThiS family
IHGKNBMB_00656 3.9e-218 narK P Transporter, major facilitator family protein
IHGKNBMB_00657 2.9e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
IHGKNBMB_00658 3.6e-182
IHGKNBMB_00659 1.6e-18
IHGKNBMB_00660 2.3e-116 nreC K PFAM regulatory protein LuxR
IHGKNBMB_00661 1e-190 comP 2.7.13.3 F Sensor histidine kinase
IHGKNBMB_00662 3e-44
IHGKNBMB_00663 2.3e-104 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IHGKNBMB_00664 5.1e-84 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
IHGKNBMB_00665 8.5e-229 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
IHGKNBMB_00666 5.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IHGKNBMB_00667 8.8e-187 moeB 2.7.7.73, 2.7.7.80 H ThiF family
IHGKNBMB_00668 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IHGKNBMB_00669 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
IHGKNBMB_00670 2.7e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
IHGKNBMB_00671 2.5e-129 narI 1.7.5.1 C Nitrate reductase
IHGKNBMB_00672 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IHGKNBMB_00673 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IHGKNBMB_00674 1.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
IHGKNBMB_00675 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IHGKNBMB_00676 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
IHGKNBMB_00677 6e-216 folP 2.5.1.15 H dihydropteroate synthase
IHGKNBMB_00678 1.8e-43
IHGKNBMB_00679 3.3e-40
IHGKNBMB_00681 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IHGKNBMB_00682 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IHGKNBMB_00683 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IHGKNBMB_00684 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IHGKNBMB_00685 3.5e-40 yheA S Belongs to the UPF0342 family
IHGKNBMB_00686 1.8e-220 yhaO L Ser Thr phosphatase family protein
IHGKNBMB_00687 0.0 L AAA domain
IHGKNBMB_00688 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IHGKNBMB_00691 1.2e-76 hit FG histidine triad
IHGKNBMB_00692 3.9e-136 ecsA V ABC transporter, ATP-binding protein
IHGKNBMB_00693 5.1e-218 ecsB U ABC transporter
IHGKNBMB_00694 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IHGKNBMB_00695 7.7e-27 S YSIRK type signal peptide
IHGKNBMB_00696 3.8e-66 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
IHGKNBMB_00697 9.5e-256 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
IHGKNBMB_00698 2.3e-145 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IHGKNBMB_00699 1.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IHGKNBMB_00700 8.8e-184 iolS C Aldo keto reductase
IHGKNBMB_00701 9.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
IHGKNBMB_00702 7.5e-58 ytzB S Small secreted protein
IHGKNBMB_00703 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IHGKNBMB_00704 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IHGKNBMB_00705 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
IHGKNBMB_00706 1.3e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IHGKNBMB_00707 1.9e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IHGKNBMB_00708 1.9e-119 ybhL S Belongs to the BI1 family
IHGKNBMB_00709 2e-115 yoaK S Protein of unknown function (DUF1275)
IHGKNBMB_00710 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHGKNBMB_00711 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IHGKNBMB_00712 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IHGKNBMB_00713 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IHGKNBMB_00714 1.4e-203 dnaB L replication initiation and membrane attachment
IHGKNBMB_00715 1.1e-170 dnaI L Primosomal protein DnaI
IHGKNBMB_00716 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IHGKNBMB_00717 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IHGKNBMB_00718 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IHGKNBMB_00719 1.8e-95 yqeG S HAD phosphatase, family IIIA
IHGKNBMB_00720 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
IHGKNBMB_00721 1.9e-47 yhbY J RNA-binding protein
IHGKNBMB_00722 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IHGKNBMB_00723 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IHGKNBMB_00724 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IHGKNBMB_00725 1.7e-139 yqeM Q Methyltransferase
IHGKNBMB_00726 2.1e-213 ylbM S Belongs to the UPF0348 family
IHGKNBMB_00727 2.9e-99 yceD S Uncharacterized ACR, COG1399
IHGKNBMB_00728 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IHGKNBMB_00729 1.5e-121 K response regulator
IHGKNBMB_00730 4.1e-278 arlS 2.7.13.3 T Histidine kinase
IHGKNBMB_00734 1.4e-124 yciB M ErfK YbiS YcfS YnhG
IHGKNBMB_00736 2.5e-101
IHGKNBMB_00737 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IHGKNBMB_00738 2.7e-70 S GyrI-like small molecule binding domain
IHGKNBMB_00739 6.4e-39 S GyrI-like small molecule binding domain
IHGKNBMB_00740 5e-122 yhiD S MgtC family
IHGKNBMB_00741 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IHGKNBMB_00742 5.9e-191 V Beta-lactamase
IHGKNBMB_00743 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHGKNBMB_00744 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IHGKNBMB_00745 4.4e-35 yozE S Belongs to the UPF0346 family
IHGKNBMB_00746 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
IHGKNBMB_00747 9.5e-172 ypmR E lipolytic protein G-D-S-L family
IHGKNBMB_00748 1.7e-151 DegV S EDD domain protein, DegV family
IHGKNBMB_00749 5.3e-113 hlyIII S protein, hemolysin III
IHGKNBMB_00750 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IHGKNBMB_00751 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IHGKNBMB_00752 0.0 yfmR S ABC transporter, ATP-binding protein
IHGKNBMB_00753 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IHGKNBMB_00754 1.5e-236 S Tetratricopeptide repeat protein
IHGKNBMB_00755 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IHGKNBMB_00756 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IHGKNBMB_00757 2.5e-204 rpsA 1.17.7.4 J Ribosomal protein S1
IHGKNBMB_00758 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IHGKNBMB_00759 8.5e-14 M Lysin motif
IHGKNBMB_00760 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
IHGKNBMB_00761 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
IHGKNBMB_00762 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IHGKNBMB_00763 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IHGKNBMB_00764 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IHGKNBMB_00765 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IHGKNBMB_00766 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IHGKNBMB_00767 1.2e-163 xerD D recombinase XerD
IHGKNBMB_00768 2.3e-167 cvfB S S1 domain
IHGKNBMB_00769 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IHGKNBMB_00770 0.0 dnaE 2.7.7.7 L DNA polymerase
IHGKNBMB_00771 3.1e-30 S Protein of unknown function (DUF2929)
IHGKNBMB_00772 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IHGKNBMB_00773 3.1e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IHGKNBMB_00774 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
IHGKNBMB_00775 1.2e-219 patA 2.6.1.1 E Aminotransferase
IHGKNBMB_00776 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IHGKNBMB_00777 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IHGKNBMB_00778 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IHGKNBMB_00779 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IHGKNBMB_00780 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
IHGKNBMB_00781 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IHGKNBMB_00782 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IHGKNBMB_00783 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IHGKNBMB_00784 1.2e-183 phoH T phosphate starvation-inducible protein PhoH
IHGKNBMB_00785 1.5e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IHGKNBMB_00786 1.1e-90 bioY S BioY family
IHGKNBMB_00787 8.3e-265 argH 4.3.2.1 E argininosuccinate lyase
IHGKNBMB_00788 2.5e-155 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IHGKNBMB_00789 2.7e-39 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IHGKNBMB_00790 1.5e-183 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IHGKNBMB_00791 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IHGKNBMB_00792 0.0 cadA P P-type ATPase
IHGKNBMB_00793 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
IHGKNBMB_00795 4.8e-154 1.6.5.2 GM NAD(P)H-binding
IHGKNBMB_00796 9e-75 K Transcriptional regulator
IHGKNBMB_00797 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
IHGKNBMB_00798 6.3e-109 proWZ P ABC transporter permease
IHGKNBMB_00799 1e-139 proV E ABC transporter, ATP-binding protein
IHGKNBMB_00800 4.5e-104 proW P ABC transporter, permease protein
IHGKNBMB_00801 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IHGKNBMB_00802 1.2e-252 clcA P chloride
IHGKNBMB_00803 7e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IHGKNBMB_00804 3.1e-103 metI P ABC transporter permease
IHGKNBMB_00805 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IHGKNBMB_00806 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
IHGKNBMB_00807 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IHGKNBMB_00808 4.5e-35 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IHGKNBMB_00809 1.9e-137 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IHGKNBMB_00810 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
IHGKNBMB_00811 0.0 trxB2 1.8.1.9 C Thioredoxin domain
IHGKNBMB_00812 8.1e-88 phoU P Plays a role in the regulation of phosphate uptake
IHGKNBMB_00813 1.1e-142
IHGKNBMB_00814 1.6e-74 ydaM M Glycosyl transferase
IHGKNBMB_00815 2.3e-162
IHGKNBMB_00816 2.9e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IHGKNBMB_00817 2.8e-170 S AI-2E family transporter
IHGKNBMB_00818 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
IHGKNBMB_00819 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
IHGKNBMB_00820 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
IHGKNBMB_00821 4.8e-88 GM epimerase
IHGKNBMB_00822 1.7e-154 ypdB V (ABC) transporter
IHGKNBMB_00823 6.2e-241 yhdP S Transporter associated domain
IHGKNBMB_00824 9.9e-85 nrdI F Belongs to the NrdI family
IHGKNBMB_00825 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
IHGKNBMB_00826 3.1e-193 yeaN P Transporter, major facilitator family protein
IHGKNBMB_00827 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IHGKNBMB_00828 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IHGKNBMB_00829 1.2e-39
IHGKNBMB_00830 0.0 lacS G Transporter
IHGKNBMB_00831 7.9e-168 tagE4 2.4.1.52 GT4 M Glycosyl transferases group 1
IHGKNBMB_00835 1.8e-267 frdC 1.3.5.4 C FAD binding domain
IHGKNBMB_00836 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IHGKNBMB_00837 2.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IHGKNBMB_00838 1.9e-161 mleR K LysR family
IHGKNBMB_00839 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHGKNBMB_00840 1.1e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
IHGKNBMB_00841 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
IHGKNBMB_00842 7.2e-169 L transposase, IS605 OrfB family
IHGKNBMB_00843 7.1e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
IHGKNBMB_00844 1.5e-25
IHGKNBMB_00845 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IHGKNBMB_00846 3e-75
IHGKNBMB_00847 7.4e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IHGKNBMB_00848 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
IHGKNBMB_00849 2.5e-135 S Belongs to the UPF0246 family
IHGKNBMB_00850 2.5e-138 S Membrane
IHGKNBMB_00851 8.1e-75 4.4.1.5 E Glyoxalase
IHGKNBMB_00852 1.5e-21
IHGKNBMB_00853 7.1e-86 yueI S Protein of unknown function (DUF1694)
IHGKNBMB_00854 1.7e-235 rarA L recombination factor protein RarA
IHGKNBMB_00855 4.4e-46
IHGKNBMB_00856 4.3e-83 usp6 T universal stress protein
IHGKNBMB_00857 2.8e-207 araR K Transcriptional regulator
IHGKNBMB_00858 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
IHGKNBMB_00859 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
IHGKNBMB_00860 1.3e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IHGKNBMB_00861 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IHGKNBMB_00862 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
IHGKNBMB_00863 8.7e-159 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IHGKNBMB_00864 2.2e-126 yloV S DAK2 domain fusion protein YloV
IHGKNBMB_00865 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IHGKNBMB_00866 6.1e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IHGKNBMB_00867 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHGKNBMB_00868 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IHGKNBMB_00869 0.0 smc D Required for chromosome condensation and partitioning
IHGKNBMB_00870 4.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IHGKNBMB_00871 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IHGKNBMB_00872 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IHGKNBMB_00873 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IHGKNBMB_00874 2e-39 ylqC S Belongs to the UPF0109 family
IHGKNBMB_00875 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IHGKNBMB_00876 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IHGKNBMB_00877 9.9e-261 yfnA E amino acid
IHGKNBMB_00878 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IHGKNBMB_00879 5.5e-58
IHGKNBMB_00880 3.2e-171 XK27_00915 C Luciferase-like monooxygenase
IHGKNBMB_00881 1.5e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
IHGKNBMB_00882 7.3e-69 S Protein of unknown function (DUF3021)
IHGKNBMB_00883 4.4e-64 K LytTr DNA-binding domain
IHGKNBMB_00884 8.8e-71 yneR S Belongs to the HesB IscA family
IHGKNBMB_00885 0.0 S membrane
IHGKNBMB_00886 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IHGKNBMB_00887 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IHGKNBMB_00888 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IHGKNBMB_00889 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
IHGKNBMB_00890 3.8e-46 gluP 3.4.21.105 S Peptidase, S54 family
IHGKNBMB_00891 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
IHGKNBMB_00892 5.6e-183 glk 2.7.1.2 G Glucokinase
IHGKNBMB_00893 3.4e-67 yqhL P Rhodanese-like protein
IHGKNBMB_00894 5.9e-22 S Protein of unknown function (DUF3042)
IHGKNBMB_00895 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IHGKNBMB_00896 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
IHGKNBMB_00897 3.4e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IHGKNBMB_00898 4.8e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IHGKNBMB_00899 3.9e-12
IHGKNBMB_00900 3.1e-153 P Belongs to the nlpA lipoprotein family
IHGKNBMB_00901 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHGKNBMB_00902 3.7e-51 S Iron-sulfur cluster assembly protein
IHGKNBMB_00903 1e-151
IHGKNBMB_00904 6.6e-174
IHGKNBMB_00905 2.5e-89 dut S Protein conserved in bacteria
IHGKNBMB_00908 8.3e-111 K Transcriptional regulator
IHGKNBMB_00909 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
IHGKNBMB_00910 1.6e-54 ysxB J Cysteine protease Prp
IHGKNBMB_00911 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IHGKNBMB_00912 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IHGKNBMB_00913 7.8e-202 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IHGKNBMB_00914 1.7e-114 J 2'-5' RNA ligase superfamily
IHGKNBMB_00915 2.2e-70 yqhY S Asp23 family, cell envelope-related function
IHGKNBMB_00916 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IHGKNBMB_00917 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IHGKNBMB_00918 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHGKNBMB_00919 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHGKNBMB_00920 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IHGKNBMB_00921 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IHGKNBMB_00922 3.3e-77 argR K Regulates arginine biosynthesis genes
IHGKNBMB_00923 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
IHGKNBMB_00924 1.7e-54
IHGKNBMB_00925 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IHGKNBMB_00926 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IHGKNBMB_00927 6.9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IHGKNBMB_00928 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IHGKNBMB_00929 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IHGKNBMB_00930 9.6e-250 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IHGKNBMB_00931 2.9e-131 stp 3.1.3.16 T phosphatase
IHGKNBMB_00932 0.0 KLT serine threonine protein kinase
IHGKNBMB_00933 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IHGKNBMB_00934 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IHGKNBMB_00935 1.8e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
IHGKNBMB_00936 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IHGKNBMB_00937 4.7e-58 asp S Asp23 family, cell envelope-related function
IHGKNBMB_00938 2.5e-138 IQ KR domain
IHGKNBMB_00939 3.3e-133 S membrane transporter protein
IHGKNBMB_00940 3e-96 S ABC-type cobalt transport system, permease component
IHGKNBMB_00941 1e-246 cbiO1 S ABC transporter, ATP-binding protein
IHGKNBMB_00942 1.8e-113 P Cobalt transport protein
IHGKNBMB_00943 1.6e-52 yvlA
IHGKNBMB_00944 0.0 yjcE P Sodium proton antiporter
IHGKNBMB_00945 2.2e-52 ypaA S Protein of unknown function (DUF1304)
IHGKNBMB_00946 3.7e-190 D Alpha beta
IHGKNBMB_00947 1e-72 K Transcriptional regulator
IHGKNBMB_00948 1.1e-161
IHGKNBMB_00949 2.6e-180 1.6.5.5 C Zinc-binding dehydrogenase
IHGKNBMB_00950 1.3e-257 G PTS system Galactitol-specific IIC component
IHGKNBMB_00951 1.4e-212 EGP Major facilitator Superfamily
IHGKNBMB_00952 5.2e-14
IHGKNBMB_00953 7.1e-63
IHGKNBMB_00954 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IHGKNBMB_00955 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IHGKNBMB_00957 1.4e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IHGKNBMB_00958 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IHGKNBMB_00959 6.1e-198 XK27_09615 S reductase
IHGKNBMB_00960 1.2e-100 nqr 1.5.1.36 S reductase
IHGKNBMB_00962 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHGKNBMB_00963 2.4e-181 K Transcriptional regulator, LacI family
IHGKNBMB_00964 1e-259 G Major Facilitator
IHGKNBMB_00965 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IHGKNBMB_00966 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IHGKNBMB_00967 3.2e-264 G Major Facilitator
IHGKNBMB_00968 6.6e-289 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IHGKNBMB_00973 5.1e-187 yegS 2.7.1.107 G Lipid kinase
IHGKNBMB_00974 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHGKNBMB_00975 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IHGKNBMB_00976 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHGKNBMB_00977 2.1e-202 camS S sex pheromone
IHGKNBMB_00978 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IHGKNBMB_00979 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IHGKNBMB_00980 1.1e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IHGKNBMB_00981 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IHGKNBMB_00982 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
IHGKNBMB_00983 3.6e-140 IQ reductase
IHGKNBMB_00984 1.7e-224 ybiT S ABC transporter
IHGKNBMB_00985 2.6e-72 V MATE efflux family protein
IHGKNBMB_00986 1.2e-256 S Phage portal protein, SPP1 family
IHGKNBMB_00987 4.2e-162 MU head morphogenesis protein, SPP1 gp7 family
IHGKNBMB_00988 2.5e-29
IHGKNBMB_00990 8.6e-35 M hydrolase, family 25
IHGKNBMB_00993 1.7e-15 M Prophage endopeptidase tail
IHGKNBMB_00994 2.5e-24 S Podovirus DNA encapsidation protein (Gp16)
IHGKNBMB_00999 1.1e-28 S T=13 icosahedral viral capsid
IHGKNBMB_01002 2.9e-44 ps461 M hydrolase, family 25
IHGKNBMB_01003 5.1e-30
IHGKNBMB_01005 4.2e-17 S Domain of unknown function (DUF4355)
IHGKNBMB_01006 4.8e-107
IHGKNBMB_01008 1.5e-18
IHGKNBMB_01010 1.6e-10
IHGKNBMB_01011 3.1e-34 S Domain of unknown function (DUF5072)
IHGKNBMB_01012 3.3e-83
IHGKNBMB_01013 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
IHGKNBMB_01014 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
IHGKNBMB_01015 2.9e-34
IHGKNBMB_01017 3.1e-55 S Plasmid pRiA4b ORF-3-like protein
IHGKNBMB_01019 1.3e-73 M PFAM NLP P60 protein
IHGKNBMB_01020 3.8e-70 yqeY S YqeY-like protein
IHGKNBMB_01021 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IHGKNBMB_01022 9.1e-265 glnPH2 P ABC transporter permease
IHGKNBMB_01023 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IHGKNBMB_01024 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IHGKNBMB_01025 1e-164 yniA G Phosphotransferase enzyme family
IHGKNBMB_01026 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IHGKNBMB_01027 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHGKNBMB_01028 1.2e-52
IHGKNBMB_01029 1.2e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IHGKNBMB_01030 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
IHGKNBMB_01031 2.8e-57
IHGKNBMB_01033 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IHGKNBMB_01034 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
IHGKNBMB_01035 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IHGKNBMB_01036 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
IHGKNBMB_01037 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IHGKNBMB_01038 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
IHGKNBMB_01039 5.6e-115 rlpA M PFAM NLP P60 protein
IHGKNBMB_01040 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IHGKNBMB_01041 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IHGKNBMB_01042 2e-58 yodB K Transcriptional regulator, HxlR family
IHGKNBMB_01043 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IHGKNBMB_01044 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHGKNBMB_01045 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IHGKNBMB_01046 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IHGKNBMB_01047 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IHGKNBMB_01048 4.4e-231 V MatE
IHGKNBMB_01049 7.4e-267 yjeM E Amino Acid
IHGKNBMB_01050 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IHGKNBMB_01051 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IHGKNBMB_01052 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
IHGKNBMB_01053 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
IHGKNBMB_01054 1.3e-08
IHGKNBMB_01055 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IHGKNBMB_01056 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IHGKNBMB_01057 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IHGKNBMB_01058 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IHGKNBMB_01059 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IHGKNBMB_01060 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IHGKNBMB_01061 2.1e-87
IHGKNBMB_01062 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
IHGKNBMB_01063 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHGKNBMB_01064 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IHGKNBMB_01065 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IHGKNBMB_01066 1.5e-172 malR K Transcriptional regulator, LacI family
IHGKNBMB_01067 6.3e-213 phbA 2.3.1.9 I Belongs to the thiolase family
IHGKNBMB_01068 6.4e-241 E amino acid
IHGKNBMB_01069 1.1e-158 spoU 2.1.1.185 J Methyltransferase
IHGKNBMB_01070 4.9e-224 oxlT P Major Facilitator Superfamily
IHGKNBMB_01071 1.3e-56 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IHGKNBMB_01072 2.5e-93 XK26_04895
IHGKNBMB_01073 7.4e-18
IHGKNBMB_01074 7.8e-272 S ABC transporter, ATP-binding protein
IHGKNBMB_01075 2.3e-142 S Putative ABC-transporter type IV
IHGKNBMB_01076 2e-106 NU mannosyl-glycoprotein
IHGKNBMB_01077 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
IHGKNBMB_01078 1.5e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
IHGKNBMB_01079 7.6e-205 nrnB S DHHA1 domain
IHGKNBMB_01081 6.9e-49
IHGKNBMB_01082 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IHGKNBMB_01083 5.8e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IHGKNBMB_01084 2e-15 S Domain of unknown function (DUF4767)
IHGKNBMB_01085 9.5e-55
IHGKNBMB_01086 5.4e-116 yrkL S Flavodoxin-like fold
IHGKNBMB_01088 3.5e-49 czrA K Transcriptional regulator, ArsR family
IHGKNBMB_01089 4.6e-38
IHGKNBMB_01090 0.0 yhcA V ABC transporter, ATP-binding protein
IHGKNBMB_01091 1.8e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IHGKNBMB_01092 2.1e-183 hrtB V ABC transporter permease
IHGKNBMB_01093 2.6e-86 ygfC K transcriptional regulator (TetR family)
IHGKNBMB_01094 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
IHGKNBMB_01095 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
IHGKNBMB_01096 3e-34
IHGKNBMB_01097 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IHGKNBMB_01099 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IHGKNBMB_01100 1.1e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IHGKNBMB_01101 5.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IHGKNBMB_01102 3e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IHGKNBMB_01103 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IHGKNBMB_01104 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IHGKNBMB_01105 1.2e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IHGKNBMB_01106 4.2e-130 IQ reductase
IHGKNBMB_01107 1.1e-159 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IHGKNBMB_01108 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHGKNBMB_01109 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHGKNBMB_01110 4.2e-77 marR K Transcriptional regulator, MarR family
IHGKNBMB_01111 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IHGKNBMB_01113 9.6e-200 xerS L Belongs to the 'phage' integrase family
IHGKNBMB_01114 1.6e-260 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IHGKNBMB_01115 1.4e-190 ganB 3.2.1.89 G arabinogalactan
IHGKNBMB_01116 7.6e-71
IHGKNBMB_01117 1.6e-27 cotH M CotH kinase protein
IHGKNBMB_01118 1.9e-101 M Glycosyl hydrolases family 25
IHGKNBMB_01120 5.2e-56
IHGKNBMB_01121 1.6e-74 yjcE P Sodium proton antiporter
IHGKNBMB_01122 1.9e-159 yjcE P Sodium proton antiporter
IHGKNBMB_01124 7.7e-91
IHGKNBMB_01125 0.0 M domain protein
IHGKNBMB_01126 1.9e-32
IHGKNBMB_01127 3.9e-187 ampC V Beta-lactamase
IHGKNBMB_01128 4.1e-239 arcA 3.5.3.6 E Arginine
IHGKNBMB_01129 4.7e-79 argR K Regulates arginine biosynthesis genes
IHGKNBMB_01130 2e-261 E Arginine ornithine antiporter
IHGKNBMB_01131 2.7e-223 arcD U Amino acid permease
IHGKNBMB_01132 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
IHGKNBMB_01133 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
IHGKNBMB_01134 6e-108 tdk 2.7.1.21 F thymidine kinase
IHGKNBMB_01135 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IHGKNBMB_01136 5.7e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IHGKNBMB_01137 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IHGKNBMB_01138 9.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IHGKNBMB_01139 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IHGKNBMB_01140 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IHGKNBMB_01141 9.9e-192 yibE S overlaps another CDS with the same product name
IHGKNBMB_01142 6.3e-129 yibF S overlaps another CDS with the same product name
IHGKNBMB_01143 5e-232 pyrP F Permease
IHGKNBMB_01144 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
IHGKNBMB_01145 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHGKNBMB_01146 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IHGKNBMB_01147 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHGKNBMB_01148 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IHGKNBMB_01149 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IHGKNBMB_01150 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IHGKNBMB_01151 4.5e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IHGKNBMB_01152 1.3e-33 ywzB S Protein of unknown function (DUF1146)
IHGKNBMB_01153 2.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHGKNBMB_01154 1.9e-178 mbl D Cell shape determining protein MreB Mrl
IHGKNBMB_01155 1e-31 S Protein of unknown function (DUF2969)
IHGKNBMB_01156 4.1e-220 rodA D Belongs to the SEDS family
IHGKNBMB_01157 3.3e-46 gcvH E glycine cleavage
IHGKNBMB_01158 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IHGKNBMB_01161 1.3e-260 S Putative peptidoglycan binding domain
IHGKNBMB_01162 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IHGKNBMB_01163 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
IHGKNBMB_01164 1.3e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IHGKNBMB_01165 1.1e-283 pipD E Dipeptidase
IHGKNBMB_01166 0.0 yfiC V ABC transporter
IHGKNBMB_01167 2.9e-310 lmrA V ABC transporter, ATP-binding protein
IHGKNBMB_01168 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHGKNBMB_01169 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IHGKNBMB_01171 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
IHGKNBMB_01172 9e-79 nusG K Psort location Cytoplasmic, score
IHGKNBMB_01175 3.8e-94 L Integrase
IHGKNBMB_01176 8.4e-42 relB L RelB antitoxin
IHGKNBMB_01177 6.8e-50 S Bacterial toxin of type II toxin-antitoxin system, YafQ
IHGKNBMB_01179 9.5e-200 gpG
IHGKNBMB_01180 9.4e-76 S Domain of unknown function (DUF4355)
IHGKNBMB_01181 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IHGKNBMB_01182 5.5e-217 patA 2.6.1.1 E Aminotransferase
IHGKNBMB_01183 5.8e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IHGKNBMB_01184 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IHGKNBMB_01185 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IHGKNBMB_01186 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IHGKNBMB_01187 2.3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IHGKNBMB_01188 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
IHGKNBMB_01189 1.9e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IHGKNBMB_01190 9e-23 UW LPXTG-motif cell wall anchor domain protein
IHGKNBMB_01191 4.2e-31 L NUMOD4 motif
IHGKNBMB_01192 3.4e-67 S Terminase RNAseH like domain
IHGKNBMB_01193 3.3e-43 L Terminase small subunit
IHGKNBMB_01194 5.4e-42 S Protein of unknown function (DUF1492)
IHGKNBMB_01195 5.2e-20 S Primase C terminal 1 (PriCT-1)
IHGKNBMB_01198 2.6e-263 L Transposase IS66 family
IHGKNBMB_01199 5.7e-33 S Transposase C of IS166 homeodomain
IHGKNBMB_01200 6.7e-62 L PFAM IS66 Orf2 family protein
IHGKNBMB_01201 1.4e-23
IHGKNBMB_01202 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
IHGKNBMB_01203 1.5e-237 lmrB EGP Major facilitator Superfamily
IHGKNBMB_01204 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IHGKNBMB_01205 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IHGKNBMB_01206 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
IHGKNBMB_01207 2.6e-80 lytE M LysM domain protein
IHGKNBMB_01208 0.0 oppD EP Psort location Cytoplasmic, score
IHGKNBMB_01209 2.3e-93 lytE M LysM domain protein
IHGKNBMB_01210 8.5e-117 O Zinc-dependent metalloprotease
IHGKNBMB_01211 4.1e-115 S Membrane
IHGKNBMB_01213 4e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IHGKNBMB_01214 4.1e-275 pipD E Dipeptidase
IHGKNBMB_01215 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IHGKNBMB_01216 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IHGKNBMB_01217 0.0 dnaK O Heat shock 70 kDa protein
IHGKNBMB_01218 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IHGKNBMB_01219 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IHGKNBMB_01220 5.8e-64
IHGKNBMB_01223 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
IHGKNBMB_01224 3.7e-54
IHGKNBMB_01225 9.9e-206 yttB EGP Major facilitator Superfamily
IHGKNBMB_01226 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IHGKNBMB_01227 2e-74 rplI J Binds to the 23S rRNA
IHGKNBMB_01228 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IHGKNBMB_01229 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IHGKNBMB_01230 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IHGKNBMB_01231 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
IHGKNBMB_01232 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHGKNBMB_01233 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHGKNBMB_01234 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IHGKNBMB_01235 1.7e-34 yaaA S S4 domain protein YaaA
IHGKNBMB_01236 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
IHGKNBMB_01237 1.6e-81 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
IHGKNBMB_01238 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IHGKNBMB_01239 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IHGKNBMB_01240 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IHGKNBMB_01241 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IHGKNBMB_01242 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IHGKNBMB_01243 9.7e-130 jag S R3H domain protein
IHGKNBMB_01244 8.7e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IHGKNBMB_01245 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IHGKNBMB_01246 0.0 asnB 6.3.5.4 E Asparagine synthase
IHGKNBMB_01247 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IHGKNBMB_01248 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
IHGKNBMB_01249 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IHGKNBMB_01250 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
IHGKNBMB_01251 1.8e-161 S reductase
IHGKNBMB_01253 3.6e-288 S amidohydrolase
IHGKNBMB_01254 2e-152 K Aminotransferase class I and II
IHGKNBMB_01255 7.3e-60 K Aminotransferase class I and II
IHGKNBMB_01256 1.4e-119 azlC E azaleucine resistance protein AzlC
IHGKNBMB_01257 7.1e-50 azlD E Branched-chain amino acid transport
IHGKNBMB_01258 5.5e-118 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IHGKNBMB_01259 4e-117 terL L Terminase
IHGKNBMB_01260 4.6e-182 S Phage portal protein
IHGKNBMB_01262 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
IHGKNBMB_01263 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IHGKNBMB_01264 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
IHGKNBMB_01265 1.4e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IHGKNBMB_01266 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IHGKNBMB_01267 2.7e-39 ptsH G phosphocarrier protein HPR
IHGKNBMB_01268 2.9e-27
IHGKNBMB_01269 0.0 clpE O Belongs to the ClpA ClpB family
IHGKNBMB_01270 2.4e-99 S Pfam:DUF3816
IHGKNBMB_01271 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
IHGKNBMB_01272 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHGKNBMB_01273 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
IHGKNBMB_01274 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IHGKNBMB_01275 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IHGKNBMB_01276 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IHGKNBMB_01277 1.7e-84 F NUDIX domain
IHGKNBMB_01278 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
IHGKNBMB_01279 3.5e-35
IHGKNBMB_01280 2.5e-212 bacI V MacB-like periplasmic core domain
IHGKNBMB_01281 1.1e-36 S sequence-specific DNA binding transcription factor activity
IHGKNBMB_01286 1.6e-64 yeaO S Protein of unknown function, DUF488
IHGKNBMB_01287 7.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IHGKNBMB_01288 3e-204 3.1.3.1 S associated with various cellular activities
IHGKNBMB_01289 4.2e-242 S Putative metallopeptidase domain
IHGKNBMB_01290 5.1e-47
IHGKNBMB_01291 0.0 pepO 3.4.24.71 O Peptidase family M13
IHGKNBMB_01292 8.4e-111 K Helix-turn-helix domain
IHGKNBMB_01293 2.1e-88 ymdB S Macro domain protein
IHGKNBMB_01294 1.6e-197 EGP Major facilitator Superfamily
IHGKNBMB_01295 2.7e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHGKNBMB_01296 1.6e-94 K Transcriptional regulator (TetR family)
IHGKNBMB_01297 5.8e-39 pspC KT PspC domain protein
IHGKNBMB_01298 6.6e-262 S Putative peptidoglycan binding domain
IHGKNBMB_01299 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
IHGKNBMB_01300 2.2e-87
IHGKNBMB_01301 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
IHGKNBMB_01302 2.6e-214 yttB EGP Major facilitator Superfamily
IHGKNBMB_01303 8.2e-103
IHGKNBMB_01304 3e-24
IHGKNBMB_01305 5.1e-173 scrR K Transcriptional regulator, LacI family
IHGKNBMB_01306 2e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IHGKNBMB_01307 5.5e-280 O Arylsulfotransferase (ASST)
IHGKNBMB_01308 3.4e-132 O Bacterial dnaA protein
IHGKNBMB_01309 3.2e-236 L Integrase core domain
IHGKNBMB_01310 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHGKNBMB_01311 1.1e-217 S CAAX protease self-immunity
IHGKNBMB_01312 1.4e-108 glnP P ABC transporter permease
IHGKNBMB_01313 4.2e-110 gluC P ABC transporter permease
IHGKNBMB_01314 7.5e-152 glnH ET ABC transporter
IHGKNBMB_01315 6.9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IHGKNBMB_01316 5.5e-83 usp1 T Belongs to the universal stress protein A family
IHGKNBMB_01317 7.6e-110 S VIT family
IHGKNBMB_01318 5e-117 S membrane
IHGKNBMB_01319 2.6e-166 czcD P cation diffusion facilitator family transporter
IHGKNBMB_01320 1.1e-124 sirR K iron dependent repressor
IHGKNBMB_01321 3.5e-31 cspC K Cold shock protein
IHGKNBMB_01322 3.6e-129 thrE S Putative threonine/serine exporter
IHGKNBMB_01323 6.7e-81 S Threonine/Serine exporter, ThrE
IHGKNBMB_01324 2.7e-120 lssY 3.6.1.27 I phosphatase
IHGKNBMB_01325 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
IHGKNBMB_01326 1.5e-275 lysP E amino acid
IHGKNBMB_01327 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IHGKNBMB_01333 1.6e-131 S Hydrolases of the alpha beta superfamily
IHGKNBMB_01334 1.3e-16 S Hydrolases of the alpha beta superfamily
IHGKNBMB_01335 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
IHGKNBMB_01336 3.4e-77 ctsR K Belongs to the CtsR family
IHGKNBMB_01337 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IHGKNBMB_01338 1e-110 K Bacterial regulatory proteins, tetR family
IHGKNBMB_01339 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHGKNBMB_01340 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHGKNBMB_01341 2.2e-202 ykiI
IHGKNBMB_01342 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IHGKNBMB_01343 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IHGKNBMB_01344 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IHGKNBMB_01345 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IHGKNBMB_01347 5.4e-14
IHGKNBMB_01350 1.8e-240 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
IHGKNBMB_01351 1.9e-130 IQ Dehydrogenase reductase
IHGKNBMB_01352 2.9e-37
IHGKNBMB_01353 4.8e-114 ywnB S NAD(P)H-binding
IHGKNBMB_01354 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
IHGKNBMB_01355 3.3e-256 nhaC C Na H antiporter NhaC
IHGKNBMB_01356 2.7e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IHGKNBMB_01358 2.1e-102 ydeN S Serine hydrolase
IHGKNBMB_01359 4.5e-62 psiE S Phosphate-starvation-inducible E
IHGKNBMB_01360 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IHGKNBMB_01361 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
IHGKNBMB_01362 0.0 helD 3.6.4.12 L DNA helicase
IHGKNBMB_01363 1.2e-115 dedA S SNARE associated Golgi protein
IHGKNBMB_01364 4.2e-126 3.1.3.73 G phosphoglycerate mutase
IHGKNBMB_01365 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IHGKNBMB_01366 6.6e-35 S Transglycosylase associated protein
IHGKNBMB_01368 2.9e-182 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHGKNBMB_01369 1.7e-144 V domain protein
IHGKNBMB_01370 5e-75 osmC O OsmC-like protein
IHGKNBMB_01371 8e-177 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHGKNBMB_01372 6.1e-216 patA 2.6.1.1 E Aminotransferase
IHGKNBMB_01373 7.8e-32
IHGKNBMB_01374 0.0 clpL O associated with various cellular activities
IHGKNBMB_01375 5.2e-50
IHGKNBMB_01376 2.1e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IHGKNBMB_01377 2.4e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IHGKNBMB_01378 5.1e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IHGKNBMB_01379 1.8e-226 clcA_2 P Chloride transporter, ClC family
IHGKNBMB_01380 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IHGKNBMB_01381 7.6e-112 lssY 3.6.1.27 I Acid phosphatase homologues
IHGKNBMB_01383 7.1e-101 ydaM M Glycosyl transferase family group 2
IHGKNBMB_01384 7.4e-219 G Glycosyl hydrolases family 8
IHGKNBMB_01385 1.1e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IHGKNBMB_01386 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
IHGKNBMB_01387 1.7e-238 ktrB P Potassium uptake protein
IHGKNBMB_01388 1.4e-116 ktrA P domain protein
IHGKNBMB_01389 1.2e-81 Q Methyltransferase
IHGKNBMB_01390 7.4e-231 mntH P H( )-stimulated, divalent metal cation uptake system
IHGKNBMB_01391 8.9e-65 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IHGKNBMB_01392 1.6e-219 norA EGP Major facilitator Superfamily
IHGKNBMB_01393 5.8e-40 1.3.5.4 S FMN binding
IHGKNBMB_01394 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IHGKNBMB_01395 1e-265 yfnA E amino acid
IHGKNBMB_01396 5.3e-256 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IHGKNBMB_01398 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IHGKNBMB_01399 0.0 helD 3.6.4.12 L DNA helicase
IHGKNBMB_01400 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
IHGKNBMB_01401 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
IHGKNBMB_01402 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IHGKNBMB_01403 1.3e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IHGKNBMB_01404 2.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IHGKNBMB_01405 1.6e-177
IHGKNBMB_01406 3e-130 cobB K SIR2 family
IHGKNBMB_01408 3.6e-162 yunF F Protein of unknown function DUF72
IHGKNBMB_01409 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHGKNBMB_01410 1.9e-155 tatD L hydrolase, TatD family
IHGKNBMB_01411 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IHGKNBMB_01412 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IHGKNBMB_01413 6.8e-37 veg S Biofilm formation stimulator VEG
IHGKNBMB_01414 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IHGKNBMB_01415 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
IHGKNBMB_01416 1.4e-121 fhuC P ABC transporter
IHGKNBMB_01417 1.4e-118 znuB U ABC 3 transport family
IHGKNBMB_01418 2.6e-149 purR 2.4.2.7 F pur operon repressor
IHGKNBMB_01419 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IHGKNBMB_01420 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHGKNBMB_01421 2.1e-49
IHGKNBMB_01422 2.5e-147 yxeH S hydrolase
IHGKNBMB_01423 5e-270 ywfO S HD domain protein
IHGKNBMB_01424 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
IHGKNBMB_01425 3e-66 ywiB S Domain of unknown function (DUF1934)
IHGKNBMB_01426 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IHGKNBMB_01427 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IHGKNBMB_01428 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHGKNBMB_01429 4.6e-41 rpmE2 J Ribosomal protein L31
IHGKNBMB_01430 1.2e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHGKNBMB_01431 1.3e-165 S Alpha/beta hydrolase of unknown function (DUF915)
IHGKNBMB_01432 1.1e-124 srtA 3.4.22.70 M sortase family
IHGKNBMB_01433 2.5e-234 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IHGKNBMB_01434 2.3e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IHGKNBMB_01435 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IHGKNBMB_01436 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
IHGKNBMB_01437 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IHGKNBMB_01438 7e-93 lemA S LemA family
IHGKNBMB_01439 2.6e-158 htpX O Belongs to the peptidase M48B family
IHGKNBMB_01440 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IHGKNBMB_01441 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IHGKNBMB_01442 1.1e-126 L PFAM Integrase catalytic region
IHGKNBMB_01443 1e-141 sprD D Domain of Unknown Function (DUF1542)
IHGKNBMB_01444 1.3e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
IHGKNBMB_01445 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IHGKNBMB_01446 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHGKNBMB_01447 3.7e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
IHGKNBMB_01448 6.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHGKNBMB_01450 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IHGKNBMB_01451 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IHGKNBMB_01452 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
IHGKNBMB_01453 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
IHGKNBMB_01454 4.7e-243 codA 3.5.4.1 F cytosine deaminase
IHGKNBMB_01455 3.1e-147 tesE Q hydratase
IHGKNBMB_01456 4e-113 S (CBS) domain
IHGKNBMB_01457 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IHGKNBMB_01458 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IHGKNBMB_01459 8.1e-39 yabO J S4 domain protein
IHGKNBMB_01460 3.3e-56 divIC D Septum formation initiator
IHGKNBMB_01461 9.8e-67 yabR J RNA binding
IHGKNBMB_01462 3.8e-257 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IHGKNBMB_01463 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IHGKNBMB_01464 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IHGKNBMB_01465 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IHGKNBMB_01466 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHGKNBMB_01467 1.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IHGKNBMB_01470 5.5e-185 L transposase, IS605 OrfB family
IHGKNBMB_01471 2.1e-50 L Transposase IS200 like
IHGKNBMB_01472 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IHGKNBMB_01473 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
IHGKNBMB_01474 2.4e-223 mdtG EGP Major facilitator Superfamily
IHGKNBMB_01475 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IHGKNBMB_01476 1.9e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IHGKNBMB_01477 5.1e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IHGKNBMB_01478 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IHGKNBMB_01479 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IHGKNBMB_01480 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
IHGKNBMB_01481 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHGKNBMB_01482 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IHGKNBMB_01483 2.7e-244 yagE E amino acid
IHGKNBMB_01484 4.5e-140 aroD S Serine hydrolase (FSH1)
IHGKNBMB_01485 8.2e-241 brnQ U Component of the transport system for branched-chain amino acids
IHGKNBMB_01486 5.2e-167 GK ROK family
IHGKNBMB_01487 0.0 tetP J elongation factor G
IHGKNBMB_01488 5.1e-81 uspA T universal stress protein
IHGKNBMB_01489 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
IHGKNBMB_01490 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHGKNBMB_01491 5.5e-158 endA V DNA/RNA non-specific endonuclease
IHGKNBMB_01492 1e-254 yifK E Amino acid permease
IHGKNBMB_01494 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IHGKNBMB_01495 1.3e-229 N Uncharacterized conserved protein (DUF2075)
IHGKNBMB_01496 4.6e-123 S SNARE associated Golgi protein
IHGKNBMB_01497 0.0 uvrA3 L excinuclease ABC, A subunit
IHGKNBMB_01498 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IHGKNBMB_01499 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IHGKNBMB_01500 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IHGKNBMB_01501 8.1e-143 S DUF218 domain
IHGKNBMB_01502 0.0 ubiB S ABC1 family
IHGKNBMB_01503 2.5e-245 yhdP S Transporter associated domain
IHGKNBMB_01504 5e-75 copY K Copper transport repressor CopY TcrY
IHGKNBMB_01505 1.3e-244 EGP Major facilitator Superfamily
IHGKNBMB_01506 1e-73 yeaL S UPF0756 membrane protein
IHGKNBMB_01507 5.6e-79 yphH S Cupin domain
IHGKNBMB_01508 3.2e-83 C Flavodoxin
IHGKNBMB_01509 1.1e-158 K LysR substrate binding domain protein
IHGKNBMB_01510 1.7e-170 1.1.1.346 C Aldo keto reductase
IHGKNBMB_01511 2.1e-39 gcvR T Belongs to the UPF0237 family
IHGKNBMB_01512 3.7e-241 XK27_08635 S UPF0210 protein
IHGKNBMB_01513 1.5e-94 K Acetyltransferase (GNAT) domain
IHGKNBMB_01514 1.2e-160 S Alpha beta hydrolase
IHGKNBMB_01515 1.1e-158 gspA M family 8
IHGKNBMB_01516 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IHGKNBMB_01517 3.8e-93
IHGKNBMB_01518 1.9e-161 degV S EDD domain protein, DegV family
IHGKNBMB_01519 0.0 FbpA K Fibronectin-binding protein
IHGKNBMB_01520 1.2e-100 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IHGKNBMB_01521 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHGKNBMB_01522 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IHGKNBMB_01523 9e-119 S Repeat protein
IHGKNBMB_01524 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IHGKNBMB_01525 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IHGKNBMB_01526 1.3e-57 XK27_04120 S Putative amino acid metabolism
IHGKNBMB_01527 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
IHGKNBMB_01528 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IHGKNBMB_01530 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IHGKNBMB_01531 4.2e-32 cspA K Cold shock protein
IHGKNBMB_01532 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IHGKNBMB_01533 1.9e-42 divIVA D DivIVA domain protein
IHGKNBMB_01534 1.1e-141 ylmH S S4 domain protein
IHGKNBMB_01535 3.2e-40 yggT S YGGT family
IHGKNBMB_01536 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IHGKNBMB_01537 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IHGKNBMB_01538 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IHGKNBMB_01539 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IHGKNBMB_01540 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IHGKNBMB_01541 2.9e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IHGKNBMB_01542 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IHGKNBMB_01543 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IHGKNBMB_01544 2.6e-56 ftsL D Cell division protein FtsL
IHGKNBMB_01545 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IHGKNBMB_01546 3.1e-77 mraZ K Belongs to the MraZ family
IHGKNBMB_01547 7.3e-56
IHGKNBMB_01548 1.2e-10 S Protein of unknown function (DUF4044)
IHGKNBMB_01549 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IHGKNBMB_01550 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IHGKNBMB_01551 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
IHGKNBMB_01552 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IHGKNBMB_01553 7.4e-134 K LysR substrate binding domain
IHGKNBMB_01554 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IHGKNBMB_01555 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IHGKNBMB_01556 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IHGKNBMB_01557 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IHGKNBMB_01558 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IHGKNBMB_01559 6.2e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
IHGKNBMB_01560 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IHGKNBMB_01561 1.1e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IHGKNBMB_01562 4.9e-177 K AI-2E family transporter
IHGKNBMB_01563 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IHGKNBMB_01564 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IHGKNBMB_01565 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IHGKNBMB_01566 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IHGKNBMB_01567 4.7e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IHGKNBMB_01568 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IHGKNBMB_01569 5.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IHGKNBMB_01570 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHGKNBMB_01571 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHGKNBMB_01572 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHGKNBMB_01573 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IHGKNBMB_01574 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IHGKNBMB_01575 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IHGKNBMB_01576 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IHGKNBMB_01577 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
IHGKNBMB_01578 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IHGKNBMB_01579 9.7e-173
IHGKNBMB_01580 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IHGKNBMB_01582 4.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IHGKNBMB_01583 1.3e-61 asp S Asp23 family, cell envelope-related function
IHGKNBMB_01584 2.1e-25
IHGKNBMB_01585 4.2e-95
IHGKNBMB_01586 5.4e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IHGKNBMB_01587 5.8e-183 K Transcriptional regulator, LacI family
IHGKNBMB_01588 2e-231 gntT EG Gluconate
IHGKNBMB_01589 7.9e-271 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IHGKNBMB_01590 4.7e-157 EG EamA-like transporter family
IHGKNBMB_01591 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IHGKNBMB_01592 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
IHGKNBMB_01593 1.5e-225 S cog cog1373
IHGKNBMB_01595 7.5e-13 Z012_10445 S phage tail tape measure protein
IHGKNBMB_01596 2.5e-119 S phage tail
IHGKNBMB_01597 4.7e-250 M Prophage endopeptidase tail
IHGKNBMB_01598 8.6e-25 S Calcineurin-like phosphoesterase
IHGKNBMB_01600 6.9e-23 S COG5546 Small integral membrane protein
IHGKNBMB_01601 4.8e-80 S peptidoglycan catabolic process
IHGKNBMB_01602 1.3e-28
IHGKNBMB_01603 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
IHGKNBMB_01604 9e-94 lacA 2.3.1.79 S Transferase hexapeptide repeat
IHGKNBMB_01605 2.6e-155 glcU U sugar transport
IHGKNBMB_01606 2e-272 yclK 2.7.13.3 T Histidine kinase
IHGKNBMB_01607 1.5e-132 K response regulator
IHGKNBMB_01609 2.8e-79 lytE M Lysin motif
IHGKNBMB_01610 2e-149 XK27_02985 S Cof-like hydrolase
IHGKNBMB_01611 2.3e-81 K Transcriptional regulator
IHGKNBMB_01612 0.0 oatA I Acyltransferase
IHGKNBMB_01613 8.7e-53
IHGKNBMB_01614 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IHGKNBMB_01615 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHGKNBMB_01616 2e-126 ybbR S YbbR-like protein
IHGKNBMB_01617 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IHGKNBMB_01618 4.8e-249 fucP G Major Facilitator Superfamily
IHGKNBMB_01619 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IHGKNBMB_01620 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHGKNBMB_01621 3.6e-168 murB 1.3.1.98 M Cell wall formation
IHGKNBMB_01622 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
IHGKNBMB_01623 4.4e-76 S PAS domain
IHGKNBMB_01624 2.6e-86 K Acetyltransferase (GNAT) domain
IHGKNBMB_01625 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IHGKNBMB_01626 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IHGKNBMB_01627 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IHGKNBMB_01628 6.3e-105 yxjI
IHGKNBMB_01629 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IHGKNBMB_01630 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IHGKNBMB_01631 6.8e-147 est 3.1.1.1 S Serine aminopeptidase, S33
IHGKNBMB_01632 1.8e-34 secG U Preprotein translocase
IHGKNBMB_01633 2.6e-291 clcA P chloride
IHGKNBMB_01634 7.1e-248 yifK E Amino acid permease
IHGKNBMB_01635 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IHGKNBMB_01636 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IHGKNBMB_01637 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IHGKNBMB_01638 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IHGKNBMB_01640 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IHGKNBMB_01641 8.8e-15
IHGKNBMB_01643 4e-170 whiA K May be required for sporulation
IHGKNBMB_01644 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IHGKNBMB_01645 1.1e-161 rapZ S Displays ATPase and GTPase activities
IHGKNBMB_01646 5.4e-245 steT E amino acid
IHGKNBMB_01647 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IHGKNBMB_01648 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IHGKNBMB_01649 1.5e-13
IHGKNBMB_01650 2.3e-116 yfbR S HD containing hydrolase-like enzyme
IHGKNBMB_01651 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IHGKNBMB_01652 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
IHGKNBMB_01653 8.7e-159 aatB ET PFAM extracellular solute-binding protein, family 3
IHGKNBMB_01654 3.8e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IHGKNBMB_01655 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IHGKNBMB_01656 3.5e-163 lutA C Cysteine-rich domain
IHGKNBMB_01657 7.5e-288 lutB C 4Fe-4S dicluster domain
IHGKNBMB_01658 3.9e-136 yrjD S LUD domain
IHGKNBMB_01659 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IHGKNBMB_01660 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IHGKNBMB_01661 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IHGKNBMB_01662 7.8e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IHGKNBMB_01663 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IHGKNBMB_01664 3.1e-32 KT PspC domain protein
IHGKNBMB_01665 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IHGKNBMB_01666 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IHGKNBMB_01667 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IHGKNBMB_01668 1.3e-114 comFC S Competence protein
IHGKNBMB_01669 1.4e-256 comFA L Helicase C-terminal domain protein
IHGKNBMB_01670 2.9e-111 yvyE 3.4.13.9 S YigZ family
IHGKNBMB_01671 1.1e-235 EGP Major facilitator Superfamily
IHGKNBMB_01672 7.4e-68 rmaI K Transcriptional regulator
IHGKNBMB_01673 9.2e-40
IHGKNBMB_01674 0.0 ydaO E amino acid
IHGKNBMB_01675 4.3e-305 ybeC E amino acid
IHGKNBMB_01676 1.1e-81 S YbaK proline--tRNA ligase associated domain protein
IHGKNBMB_01677 1.7e-219 EG GntP family permease
IHGKNBMB_01678 1e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IHGKNBMB_01679 7.7e-58
IHGKNBMB_01681 1.2e-133 mltD CBM50 M NlpC P60 family protein
IHGKNBMB_01682 5.7e-29
IHGKNBMB_01683 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
IHGKNBMB_01684 9.8e-32 ykzG S Belongs to the UPF0356 family
IHGKNBMB_01685 2.4e-78
IHGKNBMB_01686 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IHGKNBMB_01687 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IHGKNBMB_01688 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
IHGKNBMB_01689 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IHGKNBMB_01690 4.1e-275 lpdA 1.8.1.4 C Dehydrogenase
IHGKNBMB_01691 1.4e-47 yktA S Belongs to the UPF0223 family
IHGKNBMB_01692 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IHGKNBMB_01693 0.0 typA T GTP-binding protein TypA
IHGKNBMB_01694 2e-222 ftsW D Belongs to the SEDS family
IHGKNBMB_01695 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IHGKNBMB_01696 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IHGKNBMB_01697 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IHGKNBMB_01698 6.7e-198 ylbL T Belongs to the peptidase S16 family
IHGKNBMB_01699 2.6e-80 comEA L Competence protein ComEA
IHGKNBMB_01700 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
IHGKNBMB_01701 0.0 comEC S Competence protein ComEC
IHGKNBMB_01702 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
IHGKNBMB_01703 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
IHGKNBMB_01704 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IHGKNBMB_01705 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHGKNBMB_01706 3.5e-163 S Tetratricopeptide repeat
IHGKNBMB_01707 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IHGKNBMB_01708 4.8e-132 ponA V Beta-lactamase enzyme family
IHGKNBMB_01709 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
IHGKNBMB_01710 5.3e-215 uhpT EGP Major facilitator Superfamily
IHGKNBMB_01711 2.6e-255 ytjP 3.5.1.18 E Dipeptidase
IHGKNBMB_01712 1.2e-272 arcD S C4-dicarboxylate anaerobic carrier

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)