ORF_ID e_value Gene_name EC_number CAZy COGs Description
PPNEOBKF_00001 4.4e-109
PPNEOBKF_00002 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
PPNEOBKF_00003 4.1e-220 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PPNEOBKF_00004 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
PPNEOBKF_00005 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PPNEOBKF_00006 1.4e-10 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PPNEOBKF_00007 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PPNEOBKF_00008 2.6e-269 yhdG E aromatic amino acid transport protein AroP K03293
PPNEOBKF_00009 1.7e-262 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PPNEOBKF_00010 1.5e-247 dgt 3.1.5.1 F Phosphohydrolase-associated domain
PPNEOBKF_00011 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PPNEOBKF_00012 3.5e-160 K Helix-turn-helix domain, rpiR family
PPNEOBKF_00013 5.8e-230 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
PPNEOBKF_00014 1.4e-44 S Memo-like protein
PPNEOBKF_00016 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PPNEOBKF_00017 2.9e-179 adh3 C Zinc-binding dehydrogenase
PPNEOBKF_00018 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PPNEOBKF_00019 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PPNEOBKF_00020 4.3e-73 zur P Belongs to the Fur family
PPNEOBKF_00021 9.8e-45
PPNEOBKF_00022 7.7e-154 S TIGRFAM TIGR03943 family protein
PPNEOBKF_00023 1.4e-201 ycgR S Predicted permease
PPNEOBKF_00024 1.9e-22 J Ribosomal L32p protein family
PPNEOBKF_00025 8.2e-15 rpmJ J Ribosomal protein L36
PPNEOBKF_00026 7.4e-42 rpmE2 J Ribosomal protein L31
PPNEOBKF_00027 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PPNEOBKF_00028 2.3e-47 rpmB J Ribosomal L28 family
PPNEOBKF_00029 8.7e-139 S cobalamin synthesis protein
PPNEOBKF_00030 3.3e-161 P Zinc-uptake complex component A periplasmic
PPNEOBKF_00031 0.0 lysX S Uncharacterised conserved protein (DUF2156)
PPNEOBKF_00032 1.7e-246 S Putative esterase
PPNEOBKF_00033 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
PPNEOBKF_00034 1.2e-238 purD 6.3.4.13 F Belongs to the GARS family
PPNEOBKF_00035 6.8e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PPNEOBKF_00036 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PPNEOBKF_00037 5.5e-305 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
PPNEOBKF_00038 2e-32
PPNEOBKF_00039 4.7e-69 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PPNEOBKF_00040 8.9e-33 K DNA-binding transcription factor activity
PPNEOBKF_00041 4.3e-152 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
PPNEOBKF_00042 2.1e-93 S Protein of unknown function (DUF4230)
PPNEOBKF_00043 3.3e-110
PPNEOBKF_00044 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
PPNEOBKF_00045 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PPNEOBKF_00046 3.7e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PPNEOBKF_00047 0.0 M Parallel beta-helix repeats
PPNEOBKF_00048 1.6e-227 M Glycosyl transferase 4-like domain
PPNEOBKF_00049 1.3e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
PPNEOBKF_00051 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PPNEOBKF_00052 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PPNEOBKF_00053 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PPNEOBKF_00054 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PPNEOBKF_00055 0.0 S Esterase-like activity of phytase
PPNEOBKF_00056 1e-191 EGP Transmembrane secretion effector
PPNEOBKF_00058 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PPNEOBKF_00059 3.2e-84 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PPNEOBKF_00060 1.2e-238 carA 6.3.5.5 F Belongs to the CarA family
PPNEOBKF_00061 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
PPNEOBKF_00062 4.4e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
PPNEOBKF_00063 0.0 S Protein of unknown function DUF262
PPNEOBKF_00064 9.1e-116 K helix_turn_helix, Lux Regulon
PPNEOBKF_00065 1.7e-265 T Histidine kinase
PPNEOBKF_00066 1e-97 S Domain of unknown function (DUF5067)
PPNEOBKF_00067 6.6e-132 ybhL S Belongs to the BI1 family
PPNEOBKF_00068 7.5e-172 ydeD EG EamA-like transporter family
PPNEOBKF_00069 2.3e-72 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
PPNEOBKF_00070 5.7e-280 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PPNEOBKF_00071 6.1e-129 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PPNEOBKF_00072 1.2e-137 fic D Fic/DOC family
PPNEOBKF_00073 0.0 ftsK D FtsK SpoIIIE family protein
PPNEOBKF_00074 5.4e-121 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PPNEOBKF_00075 6.5e-96 cinA 3.5.1.42 S Belongs to the CinA family
PPNEOBKF_00076 4.7e-80 K Helix-turn-helix XRE-family like proteins
PPNEOBKF_00077 3.7e-40 S Protein of unknown function (DUF3046)
PPNEOBKF_00078 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PPNEOBKF_00079 2.9e-87 recX S Modulates RecA activity
PPNEOBKF_00080 1e-07
PPNEOBKF_00081 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PPNEOBKF_00082 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PPNEOBKF_00083 3.6e-25 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PPNEOBKF_00084 6.4e-193 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PPNEOBKF_00085 1.5e-109
PPNEOBKF_00086 1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
PPNEOBKF_00087 0.0 pknL 2.7.11.1 KLT PASTA
PPNEOBKF_00088 1e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
PPNEOBKF_00089 1e-122
PPNEOBKF_00090 1.2e-179 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PPNEOBKF_00091 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
PPNEOBKF_00092 8.9e-278 aspA 4.3.1.1 E Fumarase C C-terminus
PPNEOBKF_00093 3.2e-45 S Protein of unknown function (DUF2975)
PPNEOBKF_00094 3e-25 yozG K Cro/C1-type HTH DNA-binding domain
PPNEOBKF_00095 0.0 lhr L DEAD DEAH box helicase
PPNEOBKF_00096 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
PPNEOBKF_00097 6.5e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
PPNEOBKF_00098 1.4e-187 S Protein of unknown function (DUF3071)
PPNEOBKF_00099 1.4e-47 S Domain of unknown function (DUF4193)
PPNEOBKF_00100 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PPNEOBKF_00101 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PPNEOBKF_00102 2.7e-28
PPNEOBKF_00103 1.4e-12
PPNEOBKF_00104 2.5e-208 E Belongs to the peptidase S1B family
PPNEOBKF_00105 1.8e-68 T Toxic component of a toxin-antitoxin (TA) module
PPNEOBKF_00106 1.1e-49 relB L RelB antitoxin
PPNEOBKF_00107 5.4e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PPNEOBKF_00108 4.6e-165 S Sucrose-6F-phosphate phosphohydrolase
PPNEOBKF_00109 3.3e-87 P ABC-type metal ion transport system permease component
PPNEOBKF_00110 2.7e-224 S Peptidase dimerisation domain
PPNEOBKF_00111 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PPNEOBKF_00112 6.4e-40
PPNEOBKF_00113 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
PPNEOBKF_00114 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PPNEOBKF_00115 4.4e-114 S Protein of unknown function (DUF3000)
PPNEOBKF_00116 2.7e-249 rnd 3.1.13.5 J 3'-5' exonuclease
PPNEOBKF_00117 2.8e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PPNEOBKF_00118 2e-253 clcA_2 P Voltage gated chloride channel
PPNEOBKF_00119 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PPNEOBKF_00120 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PPNEOBKF_00121 1.3e-243 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PPNEOBKF_00124 1.3e-234 patB 4.4.1.8 E Aminotransferase, class I II
PPNEOBKF_00125 1.3e-224 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PPNEOBKF_00126 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
PPNEOBKF_00127 4.4e-118 safC S O-methyltransferase
PPNEOBKF_00128 1.1e-181 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
PPNEOBKF_00129 1.1e-70 yraN L Belongs to the UPF0102 family
PPNEOBKF_00130 1.9e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
PPNEOBKF_00131 4.1e-281 dprA 5.99.1.2 LU DNA recombination-mediator protein A
PPNEOBKF_00132 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
PPNEOBKF_00133 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PPNEOBKF_00134 1.6e-157 S Putative ABC-transporter type IV
PPNEOBKF_00135 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
PPNEOBKF_00137 4e-162 V ABC transporter, ATP-binding protein
PPNEOBKF_00138 1.4e-31 MV MacB-like periplasmic core domain
PPNEOBKF_00139 3.2e-60 MV MacB-like periplasmic core domain
PPNEOBKF_00140 1e-97 MV MacB-like periplasmic core domain
PPNEOBKF_00141 2.1e-54 MV MacB-like periplasmic core domain
PPNEOBKF_00142 0.0 phoN I PAP2 superfamily
PPNEOBKF_00143 2.8e-129 K helix_turn_helix, Lux Regulon
PPNEOBKF_00144 0.0 tcsS2 T Histidine kinase
PPNEOBKF_00145 1.9e-264 pip 3.4.11.5 S alpha/beta hydrolase fold
PPNEOBKF_00146 2.7e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PPNEOBKF_00147 1.6e-166 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
PPNEOBKF_00148 2.7e-146 P NLPA lipoprotein
PPNEOBKF_00149 3.8e-187 acoA 1.2.4.1 C Dehydrogenase E1 component
PPNEOBKF_00150 7.8e-183 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
PPNEOBKF_00151 7.5e-203 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PPNEOBKF_00152 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
PPNEOBKF_00153 8.4e-229 mtnE 2.6.1.83 E Aminotransferase class I and II
PPNEOBKF_00154 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PPNEOBKF_00155 6.3e-246 XK27_00240 K Fic/DOC family
PPNEOBKF_00156 2.3e-120 E Psort location Cytoplasmic, score 8.87
PPNEOBKF_00157 5.6e-59 yccF S Inner membrane component domain
PPNEOBKF_00158 2.3e-156 ksgA 2.1.1.182 J Methyltransferase domain
PPNEOBKF_00159 2.5e-66 S Cupin 2, conserved barrel domain protein
PPNEOBKF_00160 1.1e-255 KLT Protein tyrosine kinase
PPNEOBKF_00161 4.5e-79 K Psort location Cytoplasmic, score
PPNEOBKF_00162 5.9e-148
PPNEOBKF_00163 2.7e-22
PPNEOBKF_00164 5.5e-199 S Short C-terminal domain
PPNEOBKF_00165 2.7e-87 S Helix-turn-helix
PPNEOBKF_00166 1.1e-65 S Zincin-like metallopeptidase
PPNEOBKF_00167 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
PPNEOBKF_00168 2e-39
PPNEOBKF_00169 3.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PPNEOBKF_00170 2.1e-125 ypfH S Phospholipase/Carboxylesterase
PPNEOBKF_00171 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
PPNEOBKF_00173 1.2e-288 2.4.1.166 GT2 M Glycosyltransferase like family 2
PPNEOBKF_00174 2.9e-119 3.1.3.27 E haloacid dehalogenase-like hydrolase
PPNEOBKF_00175 3.5e-146 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
PPNEOBKF_00176 3.2e-187 MA20_14895 S Conserved hypothetical protein 698
PPNEOBKF_00177 1.6e-54 estB S Phospholipase/Carboxylesterase
PPNEOBKF_00178 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
PPNEOBKF_00179 1.4e-237 rutG F Permease family
PPNEOBKF_00180 6.9e-83 K AraC-like ligand binding domain
PPNEOBKF_00182 3e-53 IQ oxidoreductase activity
PPNEOBKF_00183 2.5e-136 ybbM V Uncharacterised protein family (UPF0014)
PPNEOBKF_00184 3.4e-135 ybbL V ATPases associated with a variety of cellular activities
PPNEOBKF_00185 5.4e-161 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PPNEOBKF_00186 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PPNEOBKF_00187 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
PPNEOBKF_00188 5.1e-87
PPNEOBKF_00189 2.2e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PPNEOBKF_00190 7.9e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PPNEOBKF_00191 3.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
PPNEOBKF_00192 1.9e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
PPNEOBKF_00193 1.6e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PPNEOBKF_00194 3.2e-84 argR K Regulates arginine biosynthesis genes
PPNEOBKF_00195 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PPNEOBKF_00196 2.6e-105 3.1.21.3 V type I restriction modification DNA specificity domain
PPNEOBKF_00197 4.3e-270 K Putative DNA-binding domain
PPNEOBKF_00198 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PPNEOBKF_00199 1.4e-281 argH 4.3.2.1 E argininosuccinate lyase
PPNEOBKF_00200 7.2e-109 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PPNEOBKF_00201 3.5e-143 S Putative ABC-transporter type IV
PPNEOBKF_00202 1.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PPNEOBKF_00203 3.6e-159 L Tetratricopeptide repeat
PPNEOBKF_00204 7.3e-189 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
PPNEOBKF_00206 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PPNEOBKF_00207 1.6e-99
PPNEOBKF_00208 6.8e-116 trkA P TrkA-N domain
PPNEOBKF_00209 9.5e-235 trkB P Cation transport protein
PPNEOBKF_00210 4.8e-182 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PPNEOBKF_00211 3.5e-292 recN L May be involved in recombinational repair of damaged DNA
PPNEOBKF_00212 2e-123 S Haloacid dehalogenase-like hydrolase
PPNEOBKF_00213 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
PPNEOBKF_00214 2.7e-177 V ATPases associated with a variety of cellular activities
PPNEOBKF_00215 2.8e-126 S ABC-2 family transporter protein
PPNEOBKF_00216 4e-122 S ABC-2 family transporter protein
PPNEOBKF_00217 1.9e-283 thrC 4.2.3.1 E Threonine synthase N terminus
PPNEOBKF_00218 1.4e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PPNEOBKF_00219 6.8e-93
PPNEOBKF_00220 4.7e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PPNEOBKF_00221 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PPNEOBKF_00223 2.1e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PPNEOBKF_00224 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PPNEOBKF_00225 2.7e-137 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PPNEOBKF_00226 1.3e-78 S Bacterial PH domain
PPNEOBKF_00227 3.2e-255 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
PPNEOBKF_00229 3e-93
PPNEOBKF_00230 5e-133 C Putative TM nitroreductase
PPNEOBKF_00231 5.9e-142 yijF S Domain of unknown function (DUF1287)
PPNEOBKF_00232 7.8e-70 pdxH S Pfam:Pyridox_oxidase
PPNEOBKF_00233 1.3e-54 KT RESPONSE REGULATOR receiver
PPNEOBKF_00234 1.4e-192 V VanZ like family
PPNEOBKF_00235 1.1e-109 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
PPNEOBKF_00236 1.5e-95 ypjC S Putative ABC-transporter type IV
PPNEOBKF_00237 3.5e-10 CE Amino acid permease
PPNEOBKF_00238 1.2e-147 3.6.4.12
PPNEOBKF_00240 5.2e-101 EGP Major facilitator Superfamily
PPNEOBKF_00241 3e-28 EGP Major facilitator Superfamily
PPNEOBKF_00242 1.3e-163 rpoC M heme binding
PPNEOBKF_00243 4.7e-79 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PPNEOBKF_00244 4.8e-128
PPNEOBKF_00245 2.9e-133 S SOS response associated peptidase (SRAP)
PPNEOBKF_00246 1.6e-76 qseC 2.7.13.3 T Histidine kinase
PPNEOBKF_00247 1.2e-185 S Acetyltransferase (GNAT) domain
PPNEOBKF_00249 6.9e-37 2.7.7.1, 3.6.1.13, 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
PPNEOBKF_00250 7e-56 K Transcriptional regulator
PPNEOBKF_00251 4.5e-88 MA20_25245 K FR47-like protein
PPNEOBKF_00252 1.2e-114 ydaF_1 J Acetyltransferase (GNAT) domain
PPNEOBKF_00253 1.1e-62 yeaO K Protein of unknown function, DUF488
PPNEOBKF_00254 9e-161 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PPNEOBKF_00255 8.8e-284 S Psort location Cytoplasmic, score 8.87
PPNEOBKF_00256 1.7e-108 S Domain of unknown function (DUF4194)
PPNEOBKF_00257 0.0 S Psort location Cytoplasmic, score 8.87
PPNEOBKF_00258 3.4e-299 E Serine carboxypeptidase
PPNEOBKF_00259 3.6e-162 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PPNEOBKF_00260 3.7e-171 corA P CorA-like Mg2+ transporter protein
PPNEOBKF_00261 2.6e-169 ET Bacterial periplasmic substrate-binding proteins
PPNEOBKF_00262 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PPNEOBKF_00263 3.1e-84 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
PPNEOBKF_00264 0.0 comE S Competence protein
PPNEOBKF_00265 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
PPNEOBKF_00266 3.8e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
PPNEOBKF_00267 1.5e-158 yeaZ 2.3.1.234 O Glycoprotease family
PPNEOBKF_00268 3.1e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
PPNEOBKF_00269 6.9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PPNEOBKF_00271 7e-170 M Peptidase family M23
PPNEOBKF_00272 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
PPNEOBKF_00273 3.2e-276 G ABC transporter substrate-binding protein
PPNEOBKF_00274 2.2e-240 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
PPNEOBKF_00275 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
PPNEOBKF_00276 5.7e-91
PPNEOBKF_00277 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
PPNEOBKF_00278 5.8e-88 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PPNEOBKF_00279 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
PPNEOBKF_00280 2.4e-145 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PPNEOBKF_00281 1e-127 3.2.1.8 S alpha beta
PPNEOBKF_00282 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PPNEOBKF_00283 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PPNEOBKF_00284 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
PPNEOBKF_00285 2.3e-226 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PPNEOBKF_00286 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PPNEOBKF_00287 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PPNEOBKF_00288 7.1e-308 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PPNEOBKF_00289 3.7e-208 G Bacterial extracellular solute-binding protein
PPNEOBKF_00290 1.2e-19 G Bacterial extracellular solute-binding protein
PPNEOBKF_00291 1.4e-173 G Binding-protein-dependent transport system inner membrane component
PPNEOBKF_00292 1e-168 G ABC transporter permease
PPNEOBKF_00293 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
PPNEOBKF_00294 1.5e-177 2.7.1.2 GK ROK family
PPNEOBKF_00295 6.4e-218 GK ROK family
PPNEOBKF_00296 4.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
PPNEOBKF_00297 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PPNEOBKF_00298 1.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PPNEOBKF_00299 8.9e-303 ybiT S ABC transporter
PPNEOBKF_00300 4.5e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PPNEOBKF_00301 1.1e-230 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PPNEOBKF_00302 3.9e-37 K Transcriptional regulatory protein, C terminal
PPNEOBKF_00303 1.9e-41 K Transcriptional regulatory protein, C terminal
PPNEOBKF_00304 7.1e-28 V MacB-like periplasmic core domain
PPNEOBKF_00305 6.1e-77
PPNEOBKF_00306 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PPNEOBKF_00307 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PPNEOBKF_00308 4.3e-183 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
PPNEOBKF_00309 1.5e-177 rapZ S Displays ATPase and GTPase activities
PPNEOBKF_00310 3.1e-173 whiA K May be required for sporulation
PPNEOBKF_00311 2e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
PPNEOBKF_00312 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PPNEOBKF_00313 8e-33 secG U Preprotein translocase SecG subunit
PPNEOBKF_00314 5.3e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PPNEOBKF_00315 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
PPNEOBKF_00316 3.1e-243 mepA_6 V MatE
PPNEOBKF_00318 7.5e-253 brnQ U Component of the transport system for branched-chain amino acids
PPNEOBKF_00319 1.2e-143 yoaK S Protein of unknown function (DUF1275)
PPNEOBKF_00320 2.3e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PPNEOBKF_00321 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
PPNEOBKF_00322 2.3e-221 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PPNEOBKF_00323 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PPNEOBKF_00324 7.1e-160 G Fructosamine kinase
PPNEOBKF_00325 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PPNEOBKF_00326 2.8e-156 S PAC2 family
PPNEOBKF_00330 2.6e-262
PPNEOBKF_00333 2.2e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PPNEOBKF_00334 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PPNEOBKF_00335 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
PPNEOBKF_00336 1e-131 yebC K transcriptional regulatory protein
PPNEOBKF_00337 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PPNEOBKF_00338 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PPNEOBKF_00339 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PPNEOBKF_00340 2.6e-44 yajC U Preprotein translocase subunit
PPNEOBKF_00341 2.1e-100 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PPNEOBKF_00342 2.5e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PPNEOBKF_00343 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PPNEOBKF_00344 2.7e-244
PPNEOBKF_00345 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PPNEOBKF_00346 5.7e-30
PPNEOBKF_00347 1.8e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PPNEOBKF_00348 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PPNEOBKF_00349 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
PPNEOBKF_00350 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PPNEOBKF_00351 4.4e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PPNEOBKF_00352 5.2e-192 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PPNEOBKF_00353 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
PPNEOBKF_00354 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
PPNEOBKF_00355 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
PPNEOBKF_00356 1e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PPNEOBKF_00357 1.2e-172 S Bacterial protein of unknown function (DUF881)
PPNEOBKF_00358 2.6e-31 sbp S Protein of unknown function (DUF1290)
PPNEOBKF_00359 2.6e-141 S Bacterial protein of unknown function (DUF881)
PPNEOBKF_00360 7.3e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
PPNEOBKF_00361 2.7e-120 K helix_turn_helix, mercury resistance
PPNEOBKF_00362 7.3e-62
PPNEOBKF_00364 1.3e-96 L DNA integration
PPNEOBKF_00365 4.7e-125 S GyrI-like small molecule binding domain
PPNEOBKF_00366 4.2e-35 pgp 3.1.3.18 S HAD-hyrolase-like
PPNEOBKF_00367 1.1e-61 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
PPNEOBKF_00368 0.0 helY L DEAD DEAH box helicase
PPNEOBKF_00369 7.7e-52
PPNEOBKF_00370 0.0 pafB K WYL domain
PPNEOBKF_00371 6.3e-287 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
PPNEOBKF_00373 1.2e-88 dkgB S Oxidoreductase, aldo keto reductase family protein
PPNEOBKF_00374 7.1e-141 4.1.1.44 S Carboxymuconolactone decarboxylase family
PPNEOBKF_00375 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PPNEOBKF_00376 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PPNEOBKF_00377 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
PPNEOBKF_00378 2e-91 T Domain of unknown function (DUF4234)
PPNEOBKF_00379 9.3e-101 K Bacterial regulatory proteins, tetR family
PPNEOBKF_00380 1.6e-18
PPNEOBKF_00381 3.1e-49 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
PPNEOBKF_00382 1.4e-40 K Helix-turn-helix
PPNEOBKF_00383 7e-225 hipA 2.7.11.1 S HipA N-terminal domain
PPNEOBKF_00384 1.1e-65 4.1.1.44 S Cupin domain
PPNEOBKF_00385 4e-176 S Membrane transport protein
PPNEOBKF_00386 3.8e-93 laaE K Transcriptional regulator PadR-like family
PPNEOBKF_00387 7.9e-134 magIII L endonuclease III
PPNEOBKF_00388 8.1e-131 S Enoyl-(Acyl carrier protein) reductase
PPNEOBKF_00389 5.2e-243 vbsD V MatE
PPNEOBKF_00390 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PPNEOBKF_00391 1.9e-15 KLT Protein tyrosine kinase
PPNEOBKF_00393 9.4e-145
PPNEOBKF_00394 4.7e-196 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
PPNEOBKF_00395 1e-16 K MerR family regulatory protein
PPNEOBKF_00396 1.1e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PPNEOBKF_00397 8.2e-179 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PPNEOBKF_00398 7.7e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
PPNEOBKF_00399 2.6e-180 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
PPNEOBKF_00400 4.7e-279 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PPNEOBKF_00401 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
PPNEOBKF_00402 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PPNEOBKF_00403 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
PPNEOBKF_00405 9e-161 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
PPNEOBKF_00406 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PPNEOBKF_00410 2.2e-127 3.5.1.28 M NLP P60 protein
PPNEOBKF_00411 6.5e-67 S SPP1 phage holin
PPNEOBKF_00412 1.3e-69
PPNEOBKF_00413 6.2e-50 MU outer membrane autotransporter barrel domain protein
PPNEOBKF_00414 4e-214
PPNEOBKF_00415 2.8e-64
PPNEOBKF_00416 0.0 S Prophage endopeptidase tail
PPNEOBKF_00417 1.8e-147 S phage tail
PPNEOBKF_00418 0.0 S Phage-related minor tail protein
PPNEOBKF_00419 6.3e-53
PPNEOBKF_00420 7.7e-83
PPNEOBKF_00421 3.6e-94
PPNEOBKF_00422 4.9e-72
PPNEOBKF_00423 6.1e-73
PPNEOBKF_00424 1.3e-78
PPNEOBKF_00425 2.2e-90
PPNEOBKF_00426 8.1e-65
PPNEOBKF_00427 3.8e-176 S Phage capsid family
PPNEOBKF_00428 3.7e-78
PPNEOBKF_00430 1.1e-43
PPNEOBKF_00431 7.4e-241
PPNEOBKF_00432 5.5e-280 S Phage portal protein, SPP1 Gp6-like
PPNEOBKF_00433 0.0 S Terminase
PPNEOBKF_00434 4.8e-69
PPNEOBKF_00435 6.7e-115 S Bifunctional DNA primase/polymerase, N-terminal
PPNEOBKF_00436 8.1e-66
PPNEOBKF_00439 3.2e-32 K Transcriptional regulator
PPNEOBKF_00441 1.5e-73 S HicB_like antitoxin of bacterial toxin-antitoxin system
PPNEOBKF_00442 1.3e-34 N HicA toxin of bacterial toxin-antitoxin,
PPNEOBKF_00443 9.7e-143
PPNEOBKF_00445 3e-50
PPNEOBKF_00447 1.9e-109 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
PPNEOBKF_00448 2.6e-81 V HNH endonuclease
PPNEOBKF_00449 1.5e-26
PPNEOBKF_00450 1.9e-145 K Transcriptional regulator
PPNEOBKF_00451 1.4e-275 K ParB-like nuclease domain
PPNEOBKF_00452 8.6e-93 ssb1 L Single-strand binding protein family
PPNEOBKF_00454 5.6e-36
PPNEOBKF_00456 2.2e-37
PPNEOBKF_00459 2e-122 K BRO family, N-terminal domain
PPNEOBKF_00460 3.3e-22
PPNEOBKF_00461 8.2e-53
PPNEOBKF_00462 1.9e-34
PPNEOBKF_00463 1.2e-54
PPNEOBKF_00464 2.5e-104 S Virulence protein RhuM family
PPNEOBKF_00465 3.8e-50
PPNEOBKF_00466 6e-16
PPNEOBKF_00467 5.1e-45 E IrrE N-terminal-like domain
PPNEOBKF_00468 3.9e-242 int L Phage integrase, N-terminal SAM-like domain
PPNEOBKF_00469 2e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
PPNEOBKF_00470 7.4e-208 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
PPNEOBKF_00471 3e-178 I alpha/beta hydrolase fold
PPNEOBKF_00472 1.4e-23 rarD S EamA-like transporter family
PPNEOBKF_00473 4e-71 rarD 3.4.17.13 E Rard protein
PPNEOBKF_00474 1.1e-29
PPNEOBKF_00475 0.0 S Protein of unknown function DUF262
PPNEOBKF_00476 1.1e-128 S AAA-like domain
PPNEOBKF_00477 1.2e-88 S AAA-like domain
PPNEOBKF_00478 2.5e-56 S SIR2-like domain
PPNEOBKF_00479 2.8e-182 3.1.21.4 V Type III restriction enzyme res subunit
PPNEOBKF_00480 6.9e-56 L Eco57I restriction-modification methylase
PPNEOBKF_00481 1.9e-38 L Eco57I restriction-modification methylase
PPNEOBKF_00482 0.0 KL Type III restriction enzyme res subunit
PPNEOBKF_00483 5.1e-22 XK26_04895
PPNEOBKF_00484 2.3e-31 XK26_04895
PPNEOBKF_00485 1.6e-28
PPNEOBKF_00486 9.3e-181 L Transposase
PPNEOBKF_00487 1.7e-61 S Short C-terminal domain
PPNEOBKF_00488 1.2e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PPNEOBKF_00489 1.3e-113 S Sel1-like repeats.
PPNEOBKF_00490 1.5e-158 ybeM S Carbon-nitrogen hydrolase
PPNEOBKF_00491 1.6e-182 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
PPNEOBKF_00492 1.1e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
PPNEOBKF_00493 3.6e-82
PPNEOBKF_00494 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PPNEOBKF_00495 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
PPNEOBKF_00496 0.0 tetP J Elongation factor G, domain IV
PPNEOBKF_00497 1.4e-287 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
PPNEOBKF_00498 3.4e-12 S Membrane
PPNEOBKF_00499 1.5e-245 hemN H Involved in the biosynthesis of porphyrin-containing compound
PPNEOBKF_00500 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PPNEOBKF_00501 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
PPNEOBKF_00502 1.2e-135 S UPF0126 domain
PPNEOBKF_00503 2.7e-99 3.1.4.37 T RNA ligase
PPNEOBKF_00504 1.8e-46 S phosphoesterase or phosphohydrolase
PPNEOBKF_00505 2.4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
PPNEOBKF_00506 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PPNEOBKF_00507 1.8e-189 S alpha beta
PPNEOBKF_00508 2.3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PPNEOBKF_00509 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
PPNEOBKF_00510 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
PPNEOBKF_00511 0.0 fadD 6.2.1.3 I AMP-binding enzyme
PPNEOBKF_00512 1.5e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PPNEOBKF_00513 2.4e-251 corC S CBS domain
PPNEOBKF_00514 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PPNEOBKF_00515 3.4e-197 phoH T PhoH-like protein
PPNEOBKF_00516 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
PPNEOBKF_00517 4.9e-35 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PPNEOBKF_00518 4.7e-83 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PPNEOBKF_00520 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
PPNEOBKF_00521 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PPNEOBKF_00522 1.2e-108 yitW S Iron-sulfur cluster assembly protein
PPNEOBKF_00523 2.6e-100 iscU C SUF system FeS assembly protein, NifU family
PPNEOBKF_00524 1.6e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PPNEOBKF_00525 2.4e-144 sufC O FeS assembly ATPase SufC
PPNEOBKF_00526 1.4e-234 sufD O FeS assembly protein SufD
PPNEOBKF_00527 3.6e-290 sufB O FeS assembly protein SufB
PPNEOBKF_00528 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PPNEOBKF_00529 2.6e-07 3.4.22.70 M Sortase family
PPNEOBKF_00530 1.7e-120 K helix_turn_helix, Lux Regulon
PPNEOBKF_00531 1.9e-75
PPNEOBKF_00532 5.9e-79 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
PPNEOBKF_00533 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PPNEOBKF_00534 1.6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PPNEOBKF_00535 6.3e-47 3.4.23.43 S Type IV leader peptidase family
PPNEOBKF_00536 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PPNEOBKF_00537 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PPNEOBKF_00538 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PPNEOBKF_00539 1.1e-36
PPNEOBKF_00540 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
PPNEOBKF_00541 6.5e-136 pgm3 G Phosphoglycerate mutase family
PPNEOBKF_00542 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
PPNEOBKF_00543 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PPNEOBKF_00544 1.9e-128 lolD V ABC transporter
PPNEOBKF_00545 9.4e-212 V FtsX-like permease family
PPNEOBKF_00546 8.2e-64 S Domain of unknown function (DUF4418)
PPNEOBKF_00547 0.0 pcrA 3.6.4.12 L DNA helicase
PPNEOBKF_00548 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
PPNEOBKF_00549 1.9e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PPNEOBKF_00550 2e-239 pbuX F Permease family
PPNEOBKF_00552 8.1e-47 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PPNEOBKF_00554 3.6e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
PPNEOBKF_00555 9e-40
PPNEOBKF_00556 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
PPNEOBKF_00557 5.9e-182 tnp7109-21 L Integrase core domain
PPNEOBKF_00558 8.6e-48 L Transposase
PPNEOBKF_00559 1.2e-64 D MobA/MobL family
PPNEOBKF_00560 1.3e-78
PPNEOBKF_00562 4.3e-205 L Transposase and inactivated derivatives IS30 family
PPNEOBKF_00563 2e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
PPNEOBKF_00564 3.4e-253 V ABC-2 family transporter protein
PPNEOBKF_00565 1.8e-226 V ABC-2 family transporter protein
PPNEOBKF_00566 2.9e-179 V ATPases associated with a variety of cellular activities
PPNEOBKF_00567 9.9e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
PPNEOBKF_00568 7.8e-233 T Histidine kinase
PPNEOBKF_00569 3.1e-119 K helix_turn_helix, Lux Regulon
PPNEOBKF_00570 1.1e-115 MA20_27875 P Protein of unknown function DUF47
PPNEOBKF_00571 3.4e-189 pit P Phosphate transporter family
PPNEOBKF_00572 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
PPNEOBKF_00573 8.7e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PPNEOBKF_00574 4.2e-09 S Domain of unknown function (DUF4339)
PPNEOBKF_00575 2.2e-80
PPNEOBKF_00576 6.8e-71 XK27_07020 S Domain of unknown function (DUF1846)
PPNEOBKF_00577 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PPNEOBKF_00578 9.8e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PPNEOBKF_00579 1.4e-275 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PPNEOBKF_00580 2.9e-108 3.4.13.21 E Peptidase family S51
PPNEOBKF_00582 9.7e-129
PPNEOBKF_00583 1.2e-100 3.5.1.124 S DJ-1/PfpI family
PPNEOBKF_00584 2.6e-163 1.1.1.346 S Aldo/keto reductase family
PPNEOBKF_00585 2.2e-72 K helix_turn_helix, mercury resistance
PPNEOBKF_00586 1.6e-73 K helix_turn_helix multiple antibiotic resistance protein
PPNEOBKF_00587 2e-16 U Major Facilitator Superfamily
PPNEOBKF_00588 4.8e-24 yafP 5.3.1.16 K Acetyltransferase (GNAT) domain
PPNEOBKF_00589 5.6e-43 yafP 5.3.1.16 K Acetyltransferase (GNAT) domain
PPNEOBKF_00590 2.5e-14
PPNEOBKF_00592 7.4e-217 ykiI
PPNEOBKF_00593 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
PPNEOBKF_00594 1.2e-118 3.6.1.13 L NUDIX domain
PPNEOBKF_00595 2.9e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
PPNEOBKF_00596 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PPNEOBKF_00597 9.2e-120 pdtaR T Response regulator receiver domain protein
PPNEOBKF_00599 3.3e-109 aspA 3.6.1.13 L NUDIX domain
PPNEOBKF_00600 1.9e-272 pyk 2.7.1.40 G Pyruvate kinase
PPNEOBKF_00601 2.3e-102 terC P Integral membrane protein, TerC family
PPNEOBKF_00602 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PPNEOBKF_00603 4.5e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PPNEOBKF_00604 6.8e-241 rpsA J Ribosomal protein S1
PPNEOBKF_00605 2e-163 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PPNEOBKF_00606 9.6e-173 P Zinc-uptake complex component A periplasmic
PPNEOBKF_00607 1.8e-164 znuC P ATPases associated with a variety of cellular activities
PPNEOBKF_00608 4.3e-139 znuB U ABC 3 transport family
PPNEOBKF_00609 4.2e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PPNEOBKF_00610 5.1e-102 carD K CarD-like/TRCF domain
PPNEOBKF_00611 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PPNEOBKF_00612 1.9e-127 T Response regulator receiver domain protein
PPNEOBKF_00613 1.1e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PPNEOBKF_00614 8.1e-72 rulA 3.4.21.88 KT Peptidase S24-like
PPNEOBKF_00615 9.2e-130 ctsW S Phosphoribosyl transferase domain
PPNEOBKF_00616 5e-156 cof 5.2.1.8 T Eukaryotic phosphomannomutase
PPNEOBKF_00617 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
PPNEOBKF_00618 2.2e-266
PPNEOBKF_00619 0.0 S Glycosyl transferase, family 2
PPNEOBKF_00620 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
PPNEOBKF_00621 2.4e-270 K Cell envelope-related transcriptional attenuator domain
PPNEOBKF_00622 0.0 D FtsK/SpoIIIE family
PPNEOBKF_00623 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
PPNEOBKF_00624 4.7e-285 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PPNEOBKF_00625 1.1e-140 yplQ S Haemolysin-III related
PPNEOBKF_00626 1e-107
PPNEOBKF_00628 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PPNEOBKF_00629 2.2e-72 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
PPNEOBKF_00630 6.1e-282 sdaA 4.3.1.17 E Serine dehydratase alpha chain
PPNEOBKF_00631 1e-96
PPNEOBKF_00633 2.1e-54 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
PPNEOBKF_00634 1e-119 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
PPNEOBKF_00635 5.7e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
PPNEOBKF_00636 2.5e-101 divIC D Septum formation initiator
PPNEOBKF_00637 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PPNEOBKF_00638 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
PPNEOBKF_00639 1.8e-297 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
PPNEOBKF_00640 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PPNEOBKF_00641 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PPNEOBKF_00642 1.7e-96 2.3.1.183 M Acetyltransferase (GNAT) domain
PPNEOBKF_00643 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
PPNEOBKF_00644 1e-150 GM ABC-2 type transporter
PPNEOBKF_00645 1.9e-197 GM GDP-mannose 4,6 dehydratase
PPNEOBKF_00646 5e-128 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PPNEOBKF_00649 1e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
PPNEOBKF_00650 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PPNEOBKF_00651 4e-206 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PPNEOBKF_00652 0.0 S Uncharacterised protein family (UPF0182)
PPNEOBKF_00653 2.3e-232 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
PPNEOBKF_00654 3.8e-196
PPNEOBKF_00655 3.2e-147 ytrE V ATPases associated with a variety of cellular activities
PPNEOBKF_00656 2.2e-191 V N-Acetylmuramoyl-L-alanine amidase
PPNEOBKF_00657 3e-259 argE E Peptidase dimerisation domain
PPNEOBKF_00658 5.5e-104 S Protein of unknown function (DUF3043)
PPNEOBKF_00659 5.2e-281 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PPNEOBKF_00660 9.4e-144 S Domain of unknown function (DUF4191)
PPNEOBKF_00661 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
PPNEOBKF_00662 1.3e-18
PPNEOBKF_00664 5.1e-19
PPNEOBKF_00667 7.5e-160 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
PPNEOBKF_00668 6.3e-210 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PPNEOBKF_00669 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PPNEOBKF_00670 0.0 S Tetratricopeptide repeat
PPNEOBKF_00671 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PPNEOBKF_00672 8.2e-72 2.8.2.22 S Arylsulfotransferase Ig-like domain
PPNEOBKF_00673 3.4e-138 bioM P ATPases associated with a variety of cellular activities
PPNEOBKF_00674 2e-213 E Aminotransferase class I and II
PPNEOBKF_00675 1.3e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
PPNEOBKF_00677 1.1e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PPNEOBKF_00678 0.0 ecfA GP ABC transporter, ATP-binding protein
PPNEOBKF_00679 5.2e-257 EGP Major facilitator Superfamily
PPNEOBKF_00681 5.5e-256 rarA L Recombination factor protein RarA
PPNEOBKF_00682 0.0 L DEAD DEAH box helicase
PPNEOBKF_00683 6e-194 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
PPNEOBKF_00684 1.5e-197 gluD E Binding-protein-dependent transport system inner membrane component
PPNEOBKF_00685 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
PPNEOBKF_00686 1.2e-146 gluB ET Belongs to the bacterial solute-binding protein 3 family
PPNEOBKF_00687 3.9e-139 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
PPNEOBKF_00688 8.2e-93 S Aminoacyl-tRNA editing domain
PPNEOBKF_00689 1.4e-63 K helix_turn_helix, Lux Regulon
PPNEOBKF_00690 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PPNEOBKF_00691 8.7e-262 hisS 6.1.1.21 J Histidyl-tRNA synthetase
PPNEOBKF_00692 1.7e-153 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
PPNEOBKF_00693 7.7e-33 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
PPNEOBKF_00697 0.0 clpC O ATPase family associated with various cellular activities (AAA)
PPNEOBKF_00698 4.7e-185 uspA T Belongs to the universal stress protein A family
PPNEOBKF_00699 9.5e-192 S Protein of unknown function (DUF3027)
PPNEOBKF_00700 3.8e-66 cspB K 'Cold-shock' DNA-binding domain
PPNEOBKF_00701 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PPNEOBKF_00702 1.6e-134 KT Response regulator receiver domain protein
PPNEOBKF_00703 1.2e-173
PPNEOBKF_00704 1.7e-10 S Proteins of 100 residues with WXG
PPNEOBKF_00705 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PPNEOBKF_00706 2.2e-44 cspA K 'Cold-shock' DNA-binding domain
PPNEOBKF_00707 9.9e-71 S LytR cell envelope-related transcriptional attenuator
PPNEOBKF_00708 4.4e-143 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PPNEOBKF_00709 5e-196 moxR S ATPase family associated with various cellular activities (AAA)
PPNEOBKF_00710 1.5e-175 S Protein of unknown function DUF58
PPNEOBKF_00711 6.4e-94
PPNEOBKF_00712 6.8e-190 S von Willebrand factor (vWF) type A domain
PPNEOBKF_00713 1.6e-148 S von Willebrand factor (vWF) type A domain
PPNEOBKF_00714 2.7e-74
PPNEOBKF_00716 4.4e-291 S PGAP1-like protein
PPNEOBKF_00717 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
PPNEOBKF_00718 0.0 S Lysylphosphatidylglycerol synthase TM region
PPNEOBKF_00719 8.1e-42 hup L Belongs to the bacterial histone-like protein family
PPNEOBKF_00720 8.5e-276 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
PPNEOBKF_00721 1.6e-10 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
PPNEOBKF_00722 2.4e-158 hisN 3.1.3.25 G Inositol monophosphatase family
PPNEOBKF_00723 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
PPNEOBKF_00724 0.0 arc O AAA ATPase forming ring-shaped complexes
PPNEOBKF_00725 4.7e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
PPNEOBKF_00726 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PPNEOBKF_00727 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PPNEOBKF_00728 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PPNEOBKF_00729 9.4e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PPNEOBKF_00730 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PPNEOBKF_00731 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
PPNEOBKF_00732 1.8e-175 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
PPNEOBKF_00734 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PPNEOBKF_00735 3.9e-232 ctpE P E1-E2 ATPase
PPNEOBKF_00736 1.9e-220 ctpE P E1-E2 ATPase
PPNEOBKF_00737 2e-109
PPNEOBKF_00738 4.5e-249 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PPNEOBKF_00739 6.1e-124 S Protein of unknown function (DUF3159)
PPNEOBKF_00740 2.1e-138 S Protein of unknown function (DUF3710)
PPNEOBKF_00741 1.1e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
PPNEOBKF_00742 3.1e-275 pepC 3.4.22.40 E Peptidase C1-like family
PPNEOBKF_00743 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
PPNEOBKF_00744 0.0 oppD P Belongs to the ABC transporter superfamily
PPNEOBKF_00745 4.6e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
PPNEOBKF_00746 1.8e-176 appB EP Binding-protein-dependent transport system inner membrane component
PPNEOBKF_00747 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
PPNEOBKF_00748 7.3e-42
PPNEOBKF_00749 1.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
PPNEOBKF_00750 5.5e-197 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
PPNEOBKF_00751 5.5e-92
PPNEOBKF_00752 0.0 typA T Elongation factor G C-terminus
PPNEOBKF_00753 8e-238 iscS1 2.8.1.7 E Aminotransferase class-V
PPNEOBKF_00754 1.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
PPNEOBKF_00755 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
PPNEOBKF_00756 3.7e-251 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PPNEOBKF_00757 5.6e-149 nrtR 3.6.1.55 F NUDIX hydrolase
PPNEOBKF_00758 5.4e-113 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PPNEOBKF_00759 2.3e-148 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PPNEOBKF_00760 1.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
PPNEOBKF_00761 5.8e-180 xerD D recombinase XerD
PPNEOBKF_00762 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PPNEOBKF_00763 2.1e-25 rpmI J Ribosomal protein L35
PPNEOBKF_00764 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PPNEOBKF_00765 7.1e-68 S Spermine/spermidine synthase domain
PPNEOBKF_00766 8e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
PPNEOBKF_00767 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PPNEOBKF_00768 2.4e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PPNEOBKF_00770 2e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PPNEOBKF_00771 1.4e-194 galM 5.1.3.3 G Aldose 1-epimerase
PPNEOBKF_00772 2e-64
PPNEOBKF_00773 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
PPNEOBKF_00774 4.2e-297 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PPNEOBKF_00775 6.8e-192 V Acetyltransferase (GNAT) domain
PPNEOBKF_00776 1.1e-228 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
PPNEOBKF_00777 9.5e-244 yxbA 6.3.1.12 S ATP-grasp
PPNEOBKF_00778 2.8e-128 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
PPNEOBKF_00779 0.0 smc D Required for chromosome condensation and partitioning
PPNEOBKF_00780 4.7e-283 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
PPNEOBKF_00782 9.6e-97 3.6.1.55 F NUDIX domain
PPNEOBKF_00783 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
PPNEOBKF_00784 0.0 P Belongs to the ABC transporter superfamily
PPNEOBKF_00785 1.9e-190 dppC EP Binding-protein-dependent transport system inner membrane component
PPNEOBKF_00786 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
PPNEOBKF_00787 2e-305 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
PPNEOBKF_00788 1.1e-213 nagA 3.5.1.25 G Amidohydrolase family
PPNEOBKF_00789 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PPNEOBKF_00790 7e-217 GK ROK family
PPNEOBKF_00791 9.9e-132 cutC P Participates in the control of copper homeostasis
PPNEOBKF_00792 4.5e-222 GK ROK family
PPNEOBKF_00793 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
PPNEOBKF_00794 4.4e-236 G Major Facilitator Superfamily
PPNEOBKF_00795 2.3e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PPNEOBKF_00797 1.3e-37
PPNEOBKF_00798 4.7e-158 ftsQ 6.3.2.4 D Cell division protein FtsQ
PPNEOBKF_00799 1.8e-295 murC 6.3.2.8 M Belongs to the MurCDEF family
PPNEOBKF_00800 1.7e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PPNEOBKF_00801 4e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
PPNEOBKF_00802 2.7e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PPNEOBKF_00803 1.8e-201 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PPNEOBKF_00804 4e-284 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PPNEOBKF_00805 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PPNEOBKF_00806 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
PPNEOBKF_00807 2.5e-59 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PPNEOBKF_00808 1.1e-193 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PPNEOBKF_00809 1.4e-89 mraZ K Belongs to the MraZ family
PPNEOBKF_00810 0.0 L DNA helicase
PPNEOBKF_00811 3.2e-228 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
PPNEOBKF_00812 1.1e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PPNEOBKF_00813 1.5e-43 M Lysin motif
PPNEOBKF_00814 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PPNEOBKF_00815 1.2e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PPNEOBKF_00816 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
PPNEOBKF_00817 3.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PPNEOBKF_00818 3.9e-173
PPNEOBKF_00819 2.4e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
PPNEOBKF_00820 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
PPNEOBKF_00821 1.4e-176 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
PPNEOBKF_00822 1.1e-57 EGP Major facilitator Superfamily
PPNEOBKF_00823 1.4e-248 S Domain of unknown function (DUF5067)
PPNEOBKF_00824 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
PPNEOBKF_00825 5.4e-283 S Uncharacterized protein conserved in bacteria (DUF2252)
PPNEOBKF_00826 1.7e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
PPNEOBKF_00827 4.8e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PPNEOBKF_00828 5.9e-113
PPNEOBKF_00829 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
PPNEOBKF_00830 1.2e-224 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PPNEOBKF_00831 2.5e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PPNEOBKF_00832 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
PPNEOBKF_00833 3.9e-07 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
PPNEOBKF_00835 1.2e-76 yneG S Domain of unknown function (DUF4186)
PPNEOBKF_00836 6.4e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
PPNEOBKF_00837 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
PPNEOBKF_00838 3.4e-202 K WYL domain
PPNEOBKF_00840 0.0 4.2.1.53 S MCRA family
PPNEOBKF_00841 1.6e-46 yhbY J CRS1_YhbY
PPNEOBKF_00842 7.6e-106 S zinc-ribbon domain
PPNEOBKF_00843 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
PPNEOBKF_00844 3e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
PPNEOBKF_00845 6.5e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
PPNEOBKF_00846 9.6e-191 ywqG S Domain of unknown function (DUF1963)
PPNEOBKF_00847 5.3e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PPNEOBKF_00848 4.3e-141 recO L Involved in DNA repair and RecF pathway recombination
PPNEOBKF_00849 4.7e-291 I acetylesterase activity
PPNEOBKF_00850 4.7e-236 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PPNEOBKF_00851 1.2e-222 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PPNEOBKF_00852 3.4e-198 2.7.11.1 NU Tfp pilus assembly protein FimV
PPNEOBKF_00854 4.6e-82
PPNEOBKF_00855 1.2e-145 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
PPNEOBKF_00856 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PPNEOBKF_00857 2.5e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
PPNEOBKF_00858 2.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
PPNEOBKF_00859 1e-188 ftsE D Cell division ATP-binding protein FtsE
PPNEOBKF_00860 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PPNEOBKF_00861 2.6e-138 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
PPNEOBKF_00862 6e-63
PPNEOBKF_00864 9e-178 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PPNEOBKF_00865 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PPNEOBKF_00866 9.7e-90 3.1.21.3 V DivIVA protein
PPNEOBKF_00867 2.1e-42 yggT S YGGT family
PPNEOBKF_00868 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PPNEOBKF_00869 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PPNEOBKF_00870 3.6e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PPNEOBKF_00871 7.9e-301 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
PPNEOBKF_00872 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
PPNEOBKF_00873 7.5e-158 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PPNEOBKF_00874 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PPNEOBKF_00875 1.3e-84
PPNEOBKF_00876 6.9e-231 O AAA domain (Cdc48 subfamily)
PPNEOBKF_00877 3e-162 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PPNEOBKF_00878 1.2e-61 S Thiamine-binding protein
PPNEOBKF_00879 5.2e-195 K helix_turn _helix lactose operon repressor
PPNEOBKF_00880 5.7e-47 S Protein of unknown function (DUF3052)
PPNEOBKF_00881 1.5e-152 lon T Belongs to the peptidase S16 family
PPNEOBKF_00882 1.1e-286 S Zincin-like metallopeptidase
PPNEOBKF_00883 4.5e-280 uvrD2 3.6.4.12 L DNA helicase
PPNEOBKF_00884 4.6e-245 mphA S Aminoglycoside phosphotransferase
PPNEOBKF_00885 6.1e-32 S Protein of unknown function (DUF3107)
PPNEOBKF_00886 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
PPNEOBKF_00887 7.6e-115 S Vitamin K epoxide reductase
PPNEOBKF_00888 2.5e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
PPNEOBKF_00889 4.6e-154 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PPNEOBKF_00890 2.3e-168 S Patatin-like phospholipase
PPNEOBKF_00891 4.6e-82 V ABC transporter transmembrane region
PPNEOBKF_00892 2.5e-278 V ABC transporter transmembrane region
PPNEOBKF_00893 0.0 V ABC transporter, ATP-binding protein
PPNEOBKF_00894 1.7e-88 K MarR family
PPNEOBKF_00895 8.1e-66 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
PPNEOBKF_00896 1.3e-29 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
PPNEOBKF_00897 3.9e-29 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
PPNEOBKF_00898 2.6e-30 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
PPNEOBKF_00899 1.7e-306 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
PPNEOBKF_00900 1.9e-259 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
PPNEOBKF_00901 1.2e-166
PPNEOBKF_00902 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
PPNEOBKF_00903 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
PPNEOBKF_00905 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PPNEOBKF_00906 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
PPNEOBKF_00907 3.6e-271 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PPNEOBKF_00908 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PPNEOBKF_00909 9.6e-203 S Endonuclease/Exonuclease/phosphatase family
PPNEOBKF_00912 3.1e-181 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PPNEOBKF_00913 1.3e-254 cdr OP Sulfurtransferase TusA
PPNEOBKF_00914 4.4e-149 moeB 2.7.7.80 H ThiF family
PPNEOBKF_00915 3.5e-132 tmp1 S Domain of unknown function (DUF4391)
PPNEOBKF_00916 9e-157 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
PPNEOBKF_00917 2.9e-229 aspB E Aminotransferase class-V
PPNEOBKF_00918 4.1e-105 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
PPNEOBKF_00919 1.4e-270 S zinc finger
PPNEOBKF_00920 8.8e-124 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PPNEOBKF_00921 2.1e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PPNEOBKF_00922 4.8e-291 O Subtilase family
PPNEOBKF_00923 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
PPNEOBKF_00924 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PPNEOBKF_00925 2.2e-102 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PPNEOBKF_00926 2.8e-45 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PPNEOBKF_00927 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PPNEOBKF_00928 5.5e-35 L Transposase
PPNEOBKF_00929 6.4e-24 relB L RelB antitoxin
PPNEOBKF_00930 2.7e-10 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
PPNEOBKF_00931 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
PPNEOBKF_00932 3.8e-249 G Major Facilitator Superfamily
PPNEOBKF_00933 3.4e-147 K -acetyltransferase
PPNEOBKF_00934 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
PPNEOBKF_00935 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
PPNEOBKF_00936 3.4e-269 KLT Protein tyrosine kinase
PPNEOBKF_00937 0.0 S Fibronectin type 3 domain
PPNEOBKF_00938 1.8e-232 S ATPase family associated with various cellular activities (AAA)
PPNEOBKF_00939 5.7e-231 S Protein of unknown function DUF58
PPNEOBKF_00940 0.0 E Transglutaminase-like superfamily
PPNEOBKF_00941 3.7e-165 3.1.3.16 T Sigma factor PP2C-like phosphatases
PPNEOBKF_00942 2.8e-68 B Belongs to the OprB family
PPNEOBKF_00943 7.2e-95 T Forkhead associated domain
PPNEOBKF_00944 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PPNEOBKF_00945 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PPNEOBKF_00946 7.6e-107
PPNEOBKF_00947 2.5e-185 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
PPNEOBKF_00948 6.7e-68 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
PPNEOBKF_00949 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PPNEOBKF_00951 2.5e-72
PPNEOBKF_00952 4.7e-252 S UPF0210 protein
PPNEOBKF_00953 4.2e-43 gcvR T Belongs to the UPF0237 family
PPNEOBKF_00954 8.6e-243 EGP Sugar (and other) transporter
PPNEOBKF_00955 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
PPNEOBKF_00956 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
PPNEOBKF_00957 3.1e-139 glpR K DeoR C terminal sensor domain
PPNEOBKF_00958 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
PPNEOBKF_00959 1.1e-217 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
PPNEOBKF_00960 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
PPNEOBKF_00961 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
PPNEOBKF_00962 9.9e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
PPNEOBKF_00963 4.5e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PPNEOBKF_00964 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
PPNEOBKF_00965 5.1e-27 S Uncharacterized conserved protein (DUF2183)
PPNEOBKF_00966 9.2e-201 S Uncharacterized conserved protein (DUF2183)
PPNEOBKF_00967 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
PPNEOBKF_00968 0.0 enhA_2 S L,D-transpeptidase catalytic domain
PPNEOBKF_00969 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
PPNEOBKF_00970 2.6e-160 mhpC I Alpha/beta hydrolase family
PPNEOBKF_00971 4.8e-119 F Domain of unknown function (DUF4916)
PPNEOBKF_00972 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
PPNEOBKF_00973 1.3e-179 S G5
PPNEOBKF_00974 3.2e-212
PPNEOBKF_00975 4.4e-103 K cell envelope-related transcriptional attenuator
PPNEOBKF_00976 9.9e-172 L Transposase and inactivated derivatives IS30 family
PPNEOBKF_00977 3.9e-250 EGP Major facilitator Superfamily
PPNEOBKF_00978 1.4e-224 mntH P H( )-stimulated, divalent metal cation uptake system
PPNEOBKF_00979 2.1e-134 L Protein of unknown function (DUF1524)
PPNEOBKF_00980 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
PPNEOBKF_00981 5.9e-203 K helix_turn _helix lactose operon repressor
PPNEOBKF_00982 9.2e-106 G Glycosyl hydrolases family 43
PPNEOBKF_00983 6.1e-172 G Glycosyl hydrolases family 43
PPNEOBKF_00986 1.1e-110 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PPNEOBKF_00987 1.5e-155 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PPNEOBKF_00988 0.0 fadD 6.2.1.3 I AMP-binding enzyme
PPNEOBKF_00989 2.9e-207 K helix_turn _helix lactose operon repressor
PPNEOBKF_00990 7.2e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PPNEOBKF_00991 6.8e-158 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PPNEOBKF_00992 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PPNEOBKF_00993 1.1e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
PPNEOBKF_00994 1.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
PPNEOBKF_00995 8e-293 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
PPNEOBKF_00996 3.4e-212 gatC G PTS system sugar-specific permease component
PPNEOBKF_00997 1.4e-173 K Putative sugar-binding domain
PPNEOBKF_00999 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
PPNEOBKF_01000 3.5e-277 abcT3 P ATPases associated with a variety of cellular activities
PPNEOBKF_01001 2.4e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
PPNEOBKF_01002 9.7e-34 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
PPNEOBKF_01003 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
PPNEOBKF_01004 8.2e-28 mgtC S MgtC family
PPNEOBKF_01005 1.6e-83 mgtC S MgtC family
PPNEOBKF_01007 6.9e-201
PPNEOBKF_01009 1.5e-190
PPNEOBKF_01010 0.0 pgi 5.3.1.9 G Belongs to the GPI family
PPNEOBKF_01013 2.4e-176 S Auxin Efflux Carrier
PPNEOBKF_01014 1.7e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PPNEOBKF_01015 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PPNEOBKF_01016 7.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PPNEOBKF_01018 7.6e-92 ilvN 2.2.1.6 E ACT domain
PPNEOBKF_01019 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
PPNEOBKF_01020 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PPNEOBKF_01021 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PPNEOBKF_01022 5.1e-113 yceD S Uncharacterized ACR, COG1399
PPNEOBKF_01023 3.6e-107
PPNEOBKF_01024 2.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PPNEOBKF_01025 2e-58 S Protein of unknown function (DUF3039)
PPNEOBKF_01026 0.0 yjjK S ABC transporter
PPNEOBKF_01027 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
PPNEOBKF_01028 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
PPNEOBKF_01029 1.4e-164 P Cation efflux family
PPNEOBKF_01030 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PPNEOBKF_01031 1.5e-219 S Endonuclease/Exonuclease/phosphatase family
PPNEOBKF_01032 5.9e-94 argO S LysE type translocator
PPNEOBKF_01033 2.5e-294 ydfD EK Alanine-glyoxylate amino-transferase
PPNEOBKF_01034 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PPNEOBKF_01035 8.8e-34 CP_0960 S Belongs to the UPF0109 family
PPNEOBKF_01036 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PPNEOBKF_01037 1.4e-165 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PPNEOBKF_01038 8.9e-83 hsp20 O Hsp20/alpha crystallin family
PPNEOBKF_01039 3.1e-107 XK27_02070 S Nitroreductase family
PPNEOBKF_01040 8.9e-122 rsmD 2.1.1.171 L Conserved hypothetical protein 95
PPNEOBKF_01041 1.1e-244 U Sodium:dicarboxylate symporter family
PPNEOBKF_01042 0.0
PPNEOBKF_01045 4.5e-220 steT E amino acid
PPNEOBKF_01046 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
PPNEOBKF_01047 1.4e-29 rpmB J Ribosomal L28 family
PPNEOBKF_01048 6.5e-201 yegV G pfkB family carbohydrate kinase
PPNEOBKF_01050 5e-243 yxiO S Vacuole effluxer Atg22 like
PPNEOBKF_01051 2e-132 K helix_turn_helix, mercury resistance
PPNEOBKF_01052 1.3e-08 T Toxic component of a toxin-antitoxin (TA) module
PPNEOBKF_01053 3.7e-54 relB L RelB antitoxin
PPNEOBKF_01054 1.1e-236 K Helix-turn-helix XRE-family like proteins
PPNEOBKF_01055 3.5e-129 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
PPNEOBKF_01060 2e-28
PPNEOBKF_01061 3.5e-07 S Scramblase
PPNEOBKF_01062 0.0 fadD 6.2.1.3 I AMP-binding enzyme
PPNEOBKF_01063 2.1e-42 K Transcriptional regulator
PPNEOBKF_01066 2.6e-68 M Belongs to the glycosyl hydrolase 28 family
PPNEOBKF_01067 1.2e-232 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
PPNEOBKF_01068 4.2e-239 MA20_36090 S Psort location Cytoplasmic, score 8.87
PPNEOBKF_01069 5e-119 K Bacterial regulatory proteins, tetR family
PPNEOBKF_01070 1.6e-132 M Mechanosensitive ion channel
PPNEOBKF_01071 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PPNEOBKF_01072 1.7e-27 2.1.1.72 S Protein conserved in bacteria
PPNEOBKF_01073 4.2e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
PPNEOBKF_01074 7.5e-95 S Domain of unknown function (DUF4854)
PPNEOBKF_01075 7.4e-214 3.4.22.70 M Sortase family
PPNEOBKF_01076 8.7e-282 M LPXTG cell wall anchor motif
PPNEOBKF_01077 0.0 inlJ M domain protein
PPNEOBKF_01078 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
PPNEOBKF_01079 5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PPNEOBKF_01080 5.4e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
PPNEOBKF_01081 3.9e-129 M Protein of unknown function (DUF3152)
PPNEOBKF_01082 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
PPNEOBKF_01084 1e-69 E Domain of unknown function (DUF5011)
PPNEOBKF_01085 6.5e-46 S Parallel beta-helix repeats
PPNEOBKF_01086 1.9e-14 S Parallel beta-helix repeats
PPNEOBKF_01088 6.6e-70 rplI J Binds to the 23S rRNA
PPNEOBKF_01089 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PPNEOBKF_01090 1.1e-79 ssb1 L Single-stranded DNA-binding protein
PPNEOBKF_01091 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
PPNEOBKF_01092 4.5e-172 T Pfam Adenylate and Guanylate cyclase catalytic domain
PPNEOBKF_01093 4.3e-116
PPNEOBKF_01094 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PPNEOBKF_01095 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PPNEOBKF_01096 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
PPNEOBKF_01097 7.5e-202 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
PPNEOBKF_01098 3.4e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PPNEOBKF_01099 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
PPNEOBKF_01100 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
PPNEOBKF_01101 1.8e-116 nusG K Participates in transcription elongation, termination and antitermination
PPNEOBKF_01102 4.7e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PPNEOBKF_01104 4e-231 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
PPNEOBKF_01105 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PPNEOBKF_01106 1.4e-298 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PPNEOBKF_01107 4.8e-215 K Psort location Cytoplasmic, score
PPNEOBKF_01108 3.1e-40 rpmA J Ribosomal L27 protein
PPNEOBKF_01109 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
PPNEOBKF_01110 0.0 rne 3.1.26.12 J Ribonuclease E/G family
PPNEOBKF_01111 1.7e-240 dapE 3.5.1.18 E Peptidase dimerisation domain
PPNEOBKF_01112 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
PPNEOBKF_01113 3.3e-256 V Efflux ABC transporter, permease protein
PPNEOBKF_01114 8.3e-165 V ATPases associated with a variety of cellular activities
PPNEOBKF_01115 6.8e-57
PPNEOBKF_01116 9.9e-67
PPNEOBKF_01117 1.1e-280 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
PPNEOBKF_01118 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PPNEOBKF_01119 1.8e-240 hom 1.1.1.3 E Homoserine dehydrogenase
PPNEOBKF_01120 1.9e-289 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
PPNEOBKF_01121 2.7e-40 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PPNEOBKF_01122 3e-187 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PPNEOBKF_01123 1e-108 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PPNEOBKF_01124 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PPNEOBKF_01125 4.7e-182 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
PPNEOBKF_01126 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
PPNEOBKF_01127 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
PPNEOBKF_01129 6.8e-164 IQ KR domain
PPNEOBKF_01130 6.7e-65 4.2.1.68 M Enolase C-terminal domain-like
PPNEOBKF_01131 5.3e-18 4.2.1.68 M carboxylic acid catabolic process
PPNEOBKF_01132 6.3e-185 K Bacterial regulatory proteins, lacI family
PPNEOBKF_01135 1.4e-118 cyaA 4.6.1.1 S CYTH
PPNEOBKF_01136 8.5e-163 trxA2 O Tetratricopeptide repeat
PPNEOBKF_01137 7.9e-180
PPNEOBKF_01138 5.8e-189
PPNEOBKF_01139 1.2e-164 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
PPNEOBKF_01140 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PPNEOBKF_01141 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PPNEOBKF_01142 4.9e-128
PPNEOBKF_01143 2.1e-131 K Bacterial regulatory proteins, tetR family
PPNEOBKF_01144 1.7e-50 G Transmembrane secretion effector
PPNEOBKF_01145 2.6e-158 G Transmembrane secretion effector
PPNEOBKF_01146 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PPNEOBKF_01147 2.3e-220 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
PPNEOBKF_01148 7.1e-182 S CAAX protease self-immunity
PPNEOBKF_01150 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
PPNEOBKF_01151 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PPNEOBKF_01152 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PPNEOBKF_01153 8.2e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
PPNEOBKF_01154 2.2e-251 S Calcineurin-like phosphoesterase
PPNEOBKF_01157 3.5e-67 S Domain of unknown function (DUF4143)
PPNEOBKF_01158 5.6e-103 S Domain of unknown function (DUF4143)
PPNEOBKF_01159 6.3e-298 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PPNEOBKF_01161 1.1e-124 S HAD hydrolase, family IA, variant 3
PPNEOBKF_01162 8.6e-201 P NMT1/THI5 like
PPNEOBKF_01163 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
PPNEOBKF_01164 5.8e-145
PPNEOBKF_01165 1.1e-126 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
PPNEOBKF_01166 4e-262 EGP Major facilitator Superfamily
PPNEOBKF_01167 6.8e-98 S GtrA-like protein
PPNEOBKF_01168 1.3e-62 S Macrophage migration inhibitory factor (MIF)
PPNEOBKF_01169 1.3e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
PPNEOBKF_01170 0.0 pepD E Peptidase family C69
PPNEOBKF_01171 1.3e-107 S Phosphatidylethanolamine-binding protein
PPNEOBKF_01172 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
PPNEOBKF_01173 0.0 lmrA2 V ABC transporter transmembrane region
PPNEOBKF_01174 0.0 lmrA1 V ABC transporter, ATP-binding protein
PPNEOBKF_01175 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
PPNEOBKF_01176 3.3e-191 1.1.1.65 C Aldo/keto reductase family
PPNEOBKF_01178 4e-100 M Belongs to the glycosyl hydrolase 30 family
PPNEOBKF_01179 7.9e-17 M Belongs to the glycosyl hydrolase 30 family
PPNEOBKF_01181 1.3e-258 L Phage integrase, N-terminal SAM-like domain
PPNEOBKF_01184 4.7e-105
PPNEOBKF_01185 0.0 ltrBE1 U Relaxase/Mobilisation nuclease domain
PPNEOBKF_01186 1.4e-59 S Bacterial mobilisation protein (MobC)
PPNEOBKF_01187 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PPNEOBKF_01188 2e-180 V Abi-like protein
PPNEOBKF_01189 6.5e-229 3.1.21.3 V Type I restriction modification DNA specificity domain
PPNEOBKF_01191 7.6e-299 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
PPNEOBKF_01192 5.6e-272
PPNEOBKF_01193 1.4e-13
PPNEOBKF_01194 1.4e-90 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
PPNEOBKF_01195 5e-116 K WHG domain
PPNEOBKF_01196 3.6e-37 L Psort location Cytoplasmic, score 8.87
PPNEOBKF_01197 2.1e-134 L Integrase core domain
PPNEOBKF_01198 3.5e-41 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
PPNEOBKF_01199 1.5e-265 EGP Major Facilitator Superfamily
PPNEOBKF_01200 1.2e-132
PPNEOBKF_01201 2.9e-243 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
PPNEOBKF_01202 5.5e-55 L HNH endonuclease
PPNEOBKF_01203 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
PPNEOBKF_01204 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PPNEOBKF_01205 1.6e-105 L Transposase
PPNEOBKF_01206 4.2e-42 XAC3035 O Glutaredoxin
PPNEOBKF_01207 7.4e-151 S Virulence factor BrkB
PPNEOBKF_01208 7.6e-100 bcp 1.11.1.15 O Redoxin
PPNEOBKF_01209 1.2e-39 E ABC transporter
PPNEOBKF_01210 6.7e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PPNEOBKF_01211 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PPNEOBKF_01212 0.0 V FtsX-like permease family
PPNEOBKF_01213 2.6e-129 V ABC transporter
PPNEOBKF_01214 2.4e-101 K Transcriptional regulator C-terminal region
PPNEOBKF_01215 1.8e-276 aroP E aromatic amino acid transport protein AroP K03293
PPNEOBKF_01216 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
PPNEOBKF_01218 8.8e-184 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
PPNEOBKF_01219 8.2e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PPNEOBKF_01220 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PPNEOBKF_01221 5e-254 yhjE EGP Sugar (and other) transporter
PPNEOBKF_01222 7e-298 scrT G Transporter major facilitator family protein
PPNEOBKF_01223 4.8e-78 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
PPNEOBKF_01224 8.4e-193 K helix_turn _helix lactose operon repressor
PPNEOBKF_01225 1.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PPNEOBKF_01226 3.7e-163 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PPNEOBKF_01227 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PPNEOBKF_01228 1.2e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
PPNEOBKF_01229 2.5e-247 3.5.1.104 G Polysaccharide deacetylase
PPNEOBKF_01230 4.9e-57 K Cro/C1-type HTH DNA-binding domain
PPNEOBKF_01231 2e-12 E IrrE N-terminal-like domain
PPNEOBKF_01232 3.9e-50 E IrrE N-terminal-like domain
PPNEOBKF_01233 6.8e-65
PPNEOBKF_01234 1.9e-61
PPNEOBKF_01236 2.3e-127 S Domain of unknown function (DUF4417)
PPNEOBKF_01237 1.9e-42 S Bacterial mobilisation protein (MobC)
PPNEOBKF_01238 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
PPNEOBKF_01240 3.9e-173 htpX O Belongs to the peptidase M48B family
PPNEOBKF_01241 2.5e-272 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
PPNEOBKF_01242 0.0 cadA P E1-E2 ATPase
PPNEOBKF_01243 3.9e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
PPNEOBKF_01244 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PPNEOBKF_01246 3.9e-15 2.7.7.7 L Transposase, Mutator family
PPNEOBKF_01247 2.6e-57 M Glycosyl hydrolases family 25
PPNEOBKF_01248 1.1e-36 CP_0155 3.5.1.28 M LysM domain
PPNEOBKF_01249 5.2e-33
PPNEOBKF_01250 7e-116 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
PPNEOBKF_01251 3.2e-79 L HindVP restriction endonuclease
PPNEOBKF_01253 8.6e-13
PPNEOBKF_01254 6.4e-16 L Phage integrase family
PPNEOBKF_01255 5.6e-42 tnp7109-21 L Integrase core domain
PPNEOBKF_01256 1.5e-53 tnp7109-21 L Integrase core domain
PPNEOBKF_01257 3.4e-32 L transposase activity
PPNEOBKF_01258 7e-86 yjcF Q Acetyltransferase (GNAT) domain
PPNEOBKF_01259 3.8e-156 I Serine aminopeptidase, S33
PPNEOBKF_01260 9.3e-53 ybjQ S Putative heavy-metal-binding
PPNEOBKF_01261 3.3e-41 D DivIVA domain protein
PPNEOBKF_01262 1.3e-90 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
PPNEOBKF_01263 0.0 KL Domain of unknown function (DUF3427)
PPNEOBKF_01265 5.4e-197 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PPNEOBKF_01267 2e-103
PPNEOBKF_01268 6.2e-166 yicL EG EamA-like transporter family
PPNEOBKF_01269 1.9e-205 pldB 3.1.1.5 I Serine aminopeptidase, S33
PPNEOBKF_01270 1.8e-162 pip S YhgE Pip domain protein
PPNEOBKF_01271 1e-166 pip S YhgE Pip domain protein
PPNEOBKF_01272 0.0 pip S YhgE Pip domain protein
PPNEOBKF_01273 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
PPNEOBKF_01274 1e-130 fhaA T Protein of unknown function (DUF2662)
PPNEOBKF_01275 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
PPNEOBKF_01276 4.8e-259 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
PPNEOBKF_01277 2.8e-266 rodA D Belongs to the SEDS family
PPNEOBKF_01278 3.7e-263 pbpA M penicillin-binding protein
PPNEOBKF_01279 2e-183 T Protein tyrosine kinase
PPNEOBKF_01280 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
PPNEOBKF_01281 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
PPNEOBKF_01282 1.8e-231 srtA 3.4.22.70 M Sortase family
PPNEOBKF_01283 7.9e-143 S Bacterial protein of unknown function (DUF881)
PPNEOBKF_01284 2.6e-71 crgA D Involved in cell division
PPNEOBKF_01285 1.4e-256 L ribosomal rna small subunit methyltransferase
PPNEOBKF_01286 1.3e-120 L HTH-like domain
PPNEOBKF_01287 1.9e-144 gluP 3.4.21.105 S Rhomboid family
PPNEOBKF_01288 3.4e-35
PPNEOBKF_01289 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PPNEOBKF_01290 2e-73 I Sterol carrier protein
PPNEOBKF_01291 8.7e-46 L Transposase
PPNEOBKF_01292 2.5e-52 L IstB-like ATP binding protein
PPNEOBKF_01293 1.1e-42 tnp7109-21 L Integrase core domain
PPNEOBKF_01294 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
PPNEOBKF_01295 3.5e-12
PPNEOBKF_01296 2e-118 K Bacterial regulatory proteins, tetR family
PPNEOBKF_01297 1.5e-215 G Transmembrane secretion effector
PPNEOBKF_01298 4e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PPNEOBKF_01299 1.5e-101
PPNEOBKF_01300 2.6e-43 3.6.1.13 L NUDIX domain
PPNEOBKF_01301 1.6e-224 glf 5.4.99.9 M UDP-galactopyranose mutase
PPNEOBKF_01302 3.8e-194 L Transposase, Mutator family
PPNEOBKF_01303 2.7e-156 bglA 3.2.1.21 G Glycosyl hydrolase family 1
PPNEOBKF_01304 9.5e-45 L Transposase DDE domain
PPNEOBKF_01306 3.3e-09
PPNEOBKF_01307 2.6e-43 L Transposase
PPNEOBKF_01308 7.3e-119 tnp7109-21 L Integrase core domain
PPNEOBKF_01309 1.2e-153 K Transposase IS116 IS110 IS902
PPNEOBKF_01310 4.4e-15 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
PPNEOBKF_01311 3.2e-215 1.1.1.22 M UDP binding domain
PPNEOBKF_01312 0.0 wbbM M Glycosyl transferase family 8
PPNEOBKF_01313 2.5e-139 rgpC U Transport permease protein
PPNEOBKF_01314 1.8e-240 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
PPNEOBKF_01315 0.0 2.1.1.72, 3.1.4.46, 3.2.1.1 GH13 M hydrolase, family 25
PPNEOBKF_01316 5.6e-121 L Protein of unknown function (DUF1524)
PPNEOBKF_01317 2.1e-142 M Putative cell wall binding repeat 2
PPNEOBKF_01318 5.7e-254 L Transposase
PPNEOBKF_01319 9.8e-127 L IstB-like ATP binding protein
PPNEOBKF_01320 0.0 M Belongs to the glycosyl hydrolase 43 family
PPNEOBKF_01321 2.6e-174 ppm1 GT2 M Glycosyl transferase, family 2
PPNEOBKF_01322 0.0 wbbM M Glycosyl transferase family 8
PPNEOBKF_01323 4.3e-298
PPNEOBKF_01324 1.3e-207 S Acyltransferase family
PPNEOBKF_01325 2.8e-72 L Transposase
PPNEOBKF_01326 6.5e-167 rfbJ M Glycosyl transferase family 2
PPNEOBKF_01327 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
PPNEOBKF_01328 1.1e-24 I transferase activity, transferring acyl groups other than amino-acyl groups
PPNEOBKF_01329 2.3e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PPNEOBKF_01330 2.7e-111 T protein histidine kinase activity
PPNEOBKF_01331 1e-47 S Protein of unknown function (DUF3073)
PPNEOBKF_01332 3.2e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PPNEOBKF_01333 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
PPNEOBKF_01334 1.4e-177 S Amidohydrolase family
PPNEOBKF_01335 0.0 yjjP S Threonine/Serine exporter, ThrE
PPNEOBKF_01336 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PPNEOBKF_01337 4.3e-239 yhjX EGP Major facilitator Superfamily
PPNEOBKF_01338 1.3e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
PPNEOBKF_01339 0.0 trxB1 1.8.1.9 C Thioredoxin domain
PPNEOBKF_01340 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
PPNEOBKF_01341 6.9e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
PPNEOBKF_01342 1.1e-95 K helix_turn _helix lactose operon repressor
PPNEOBKF_01343 3.6e-241 ytfL P Transporter associated domain
PPNEOBKF_01344 1.3e-188 yddG EG EamA-like transporter family
PPNEOBKF_01345 1.9e-83 dps P Belongs to the Dps family
PPNEOBKF_01346 1.9e-135 S Protein of unknown function DUF45
PPNEOBKF_01347 2.8e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
PPNEOBKF_01348 9.6e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
PPNEOBKF_01349 4.3e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PPNEOBKF_01350 3.9e-190 K helix_turn _helix lactose operon repressor
PPNEOBKF_01351 0.0 G Glycosyl hydrolase family 20, domain 2
PPNEOBKF_01354 0.0 3.2.1.55 GH51 G arabinose metabolic process
PPNEOBKF_01355 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PPNEOBKF_01356 2.5e-124 gntR K FCD
PPNEOBKF_01357 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PPNEOBKF_01358 2.1e-24 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PPNEOBKF_01360 8.3e-09 K helix_turn _helix lactose operon repressor
PPNEOBKF_01361 2.6e-227 I Serine aminopeptidase, S33
PPNEOBKF_01362 1.6e-187 K Periplasmic binding protein domain
PPNEOBKF_01363 4.6e-187 G Glycosyl hydrolases family 43
PPNEOBKF_01365 2.6e-15 abfA1 3.2.1.55 GH51 G arabinose metabolic process
PPNEOBKF_01366 4.6e-73 S Transmembrane domain of unknown function (DUF3566)
PPNEOBKF_01367 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PPNEOBKF_01368 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PPNEOBKF_01369 2e-87 S Protein of unknown function (DUF721)
PPNEOBKF_01370 2e-239 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PPNEOBKF_01371 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PPNEOBKF_01372 4.1e-300 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PPNEOBKF_01373 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PPNEOBKF_01374 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
PPNEOBKF_01375 8.6e-93 jag S Putative single-stranded nucleic acids-binding domain
PPNEOBKF_01376 1.3e-125 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PPNEOBKF_01377 8.5e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
PPNEOBKF_01378 1.2e-242 parB K Belongs to the ParB family
PPNEOBKF_01379 2.6e-203 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PPNEOBKF_01380 0.0 murJ KLT MviN-like protein
PPNEOBKF_01381 0.0 M Conserved repeat domain
PPNEOBKF_01382 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
PPNEOBKF_01383 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
PPNEOBKF_01384 6.7e-113 S LytR cell envelope-related transcriptional attenuator
PPNEOBKF_01385 9.3e-168 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PPNEOBKF_01386 4.8e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PPNEOBKF_01387 1.2e-211 S G5
PPNEOBKF_01389 7.1e-150 O Thioredoxin
PPNEOBKF_01390 0.0 KLT Protein tyrosine kinase
PPNEOBKF_01391 1.3e-173 K Psort location Cytoplasmic, score
PPNEOBKF_01392 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
PPNEOBKF_01393 2.3e-101 L Helix-turn-helix domain
PPNEOBKF_01394 0.0 S LPXTG-motif cell wall anchor domain protein
PPNEOBKF_01395 0.0 S LPXTG-motif cell wall anchor domain protein
PPNEOBKF_01396 1.4e-250 M LPXTG-motif cell wall anchor domain protein
PPNEOBKF_01397 4.5e-180 3.4.22.70 M Sortase family
PPNEOBKF_01398 5.4e-153
PPNEOBKF_01399 1e-270 KLT Domain of unknown function (DUF4032)
PPNEOBKF_01400 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PPNEOBKF_01402 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
PPNEOBKF_01403 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
PPNEOBKF_01404 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
PPNEOBKF_01405 0.0 yjcE P Sodium/hydrogen exchanger family
PPNEOBKF_01406 1.2e-145 ypfH S Phospholipase/Carboxylesterase
PPNEOBKF_01407 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PPNEOBKF_01408 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
PPNEOBKF_01409 4e-144 cobB2 K Sir2 family
PPNEOBKF_01410 5.4e-189 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PPNEOBKF_01411 1.3e-154 sapF E ATPases associated with a variety of cellular activities
PPNEOBKF_01412 2.6e-141 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
PPNEOBKF_01413 1.6e-161 EP Binding-protein-dependent transport system inner membrane component
PPNEOBKF_01414 4.6e-169 P Binding-protein-dependent transport system inner membrane component
PPNEOBKF_01415 1.3e-309 E ABC transporter, substrate-binding protein, family 5
PPNEOBKF_01416 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PPNEOBKF_01417 1.7e-276 G Bacterial extracellular solute-binding protein
PPNEOBKF_01418 3.8e-66 G carbohydrate transport
PPNEOBKF_01419 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
PPNEOBKF_01420 2.5e-124 G ABC transporter permease
PPNEOBKF_01421 2.9e-190 K Periplasmic binding protein domain
PPNEOBKF_01422 8.5e-20 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PPNEOBKF_01423 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
PPNEOBKF_01424 3.3e-22 L Helix-turn-helix domain
PPNEOBKF_01425 3.4e-18 S Protein of unknown function (DUF2442)
PPNEOBKF_01426 2.6e-16 K Helix-turn-helix domain
PPNEOBKF_01427 2.9e-107 L Belongs to the 'phage' integrase family
PPNEOBKF_01428 2.4e-55 hsdS 3.1.21.3 V I restriction modification system specificity determinant
PPNEOBKF_01429 5.2e-244 hsdM 2.1.1.72 V HsdM N-terminal domain
PPNEOBKF_01430 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PPNEOBKF_01431 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PPNEOBKF_01432 3.8e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PPNEOBKF_01433 3e-273 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
PPNEOBKF_01434 1.8e-127 XK27_08050 O prohibitin homologues
PPNEOBKF_01435 2.2e-243 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
PPNEOBKF_01436 4.1e-231 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PPNEOBKF_01437 4.7e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
PPNEOBKF_01438 8.1e-227 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PPNEOBKF_01439 0.0 macB_2 V ATPases associated with a variety of cellular activities
PPNEOBKF_01440 0.0 ctpE P E1-E2 ATPase
PPNEOBKF_01441 3.6e-93 K acetyltransferase
PPNEOBKF_01442 1.7e-79 EGP Major Facilitator Superfamily
PPNEOBKF_01443 7.1e-197 yghZ C Aldo/keto reductase family
PPNEOBKF_01444 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
PPNEOBKF_01445 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
PPNEOBKF_01446 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
PPNEOBKF_01447 1.5e-121 S Short repeat of unknown function (DUF308)
PPNEOBKF_01448 0.0 pepO 3.4.24.71 O Peptidase family M13
PPNEOBKF_01449 2.1e-97 L Single-strand binding protein family
PPNEOBKF_01450 2.4e-170
PPNEOBKF_01451 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PPNEOBKF_01454 3e-270 recD2 3.6.4.12 L PIF1-like helicase
PPNEOBKF_01455 9e-161 supH S Sucrose-6F-phosphate phosphohydrolase
PPNEOBKF_01456 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
PPNEOBKF_01457 1.2e-24 KT Transcriptional regulatory protein, C terminal
PPNEOBKF_01458 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
PPNEOBKF_01459 3.5e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PPNEOBKF_01460 6.2e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
PPNEOBKF_01461 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
PPNEOBKF_01462 2.4e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
PPNEOBKF_01463 3e-184 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PPNEOBKF_01464 1.2e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PPNEOBKF_01465 3.9e-36 rpmE J Binds the 23S rRNA
PPNEOBKF_01467 2.1e-196 K helix_turn_helix, arabinose operon control protein
PPNEOBKF_01468 2.6e-163 glcU G Sugar transport protein
PPNEOBKF_01469 1.3e-177 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
PPNEOBKF_01470 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
PPNEOBKF_01471 1.5e-108
PPNEOBKF_01472 8.3e-170 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
PPNEOBKF_01473 1.2e-141 3.5.2.6 V Beta-lactamase enzyme family
PPNEOBKF_01474 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
PPNEOBKF_01475 4.2e-164 EG EamA-like transporter family
PPNEOBKF_01477 1.1e-140 V FtsX-like permease family
PPNEOBKF_01478 3.4e-147 S Sulfite exporter TauE/SafE
PPNEOBKF_01480 1.9e-26 L Transposase
PPNEOBKF_01481 1.7e-215 MA20_36090 S Psort location Cytoplasmic, score 8.87
PPNEOBKF_01482 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
PPNEOBKF_01483 9.3e-36 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
PPNEOBKF_01484 6.8e-73 EGP Major facilitator superfamily
PPNEOBKF_01485 4e-10 K Winged helix DNA-binding domain
PPNEOBKF_01486 3.7e-179 glkA 2.7.1.2 G ROK family
PPNEOBKF_01487 7.8e-299 S ATPases associated with a variety of cellular activities
PPNEOBKF_01488 1.2e-55 EGP Major facilitator Superfamily
PPNEOBKF_01489 1.1e-158 I alpha/beta hydrolase fold
PPNEOBKF_01490 1.1e-110 S Pyridoxamine 5'-phosphate oxidase
PPNEOBKF_01492 1.3e-55 S DUF218 domain
PPNEOBKF_01493 6.3e-17 S Protein of unknown function (DUF979)
PPNEOBKF_01494 1.7e-114 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PPNEOBKF_01496 1.8e-59
PPNEOBKF_01497 4.6e-35
PPNEOBKF_01498 4.7e-48 M domain, Protein
PPNEOBKF_01499 9.6e-15 M domain, Protein
PPNEOBKF_01500 2.8e-37 S Protein of unknown function (DUF3791)
PPNEOBKF_01501 1.4e-89 S Protein of unknown function (DUF3990)
PPNEOBKF_01502 2e-07
PPNEOBKF_01503 5.6e-67 fic D Fic/DOC family
PPNEOBKF_01504 3.2e-25 fic D Fic/DOC family
PPNEOBKF_01506 1.2e-97 S Domain of unknown function (DUF4825)
PPNEOBKF_01507 2.5e-43 K response regulator
PPNEOBKF_01508 2.1e-45 T response regulator
PPNEOBKF_01509 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
PPNEOBKF_01510 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
PPNEOBKF_01511 7.1e-172 tesB I Thioesterase-like superfamily
PPNEOBKF_01512 1.3e-77 S Protein of unknown function (DUF3180)
PPNEOBKF_01513 2.1e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PPNEOBKF_01514 2.3e-164 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PPNEOBKF_01515 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
PPNEOBKF_01516 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PPNEOBKF_01517 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PPNEOBKF_01518 1.1e-211 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PPNEOBKF_01519 4.5e-261 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
PPNEOBKF_01520 5e-309
PPNEOBKF_01521 1.7e-168 natA V ATPases associated with a variety of cellular activities
PPNEOBKF_01522 1.3e-232 epsG M Glycosyl transferase family 21
PPNEOBKF_01523 4.3e-273 S AI-2E family transporter
PPNEOBKF_01524 4.3e-177 3.4.14.13 M Glycosyltransferase like family 2
PPNEOBKF_01525 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
PPNEOBKF_01528 2.6e-68 S Domain of unknown function (DUF4190)
PPNEOBKF_01529 1.2e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PPNEOBKF_01530 1.1e-175 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PPNEOBKF_01532 8.6e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
PPNEOBKF_01533 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
PPNEOBKF_01534 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
PPNEOBKF_01535 6.3e-181 lacR K Transcriptional regulator, LacI family
PPNEOBKF_01536 5.2e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PPNEOBKF_01537 3.9e-119 K Transcriptional regulatory protein, C terminal
PPNEOBKF_01538 4.8e-101
PPNEOBKF_01539 1.5e-178 V N-Acetylmuramoyl-L-alanine amidase
PPNEOBKF_01540 1.6e-108 ytrE V ABC transporter
PPNEOBKF_01541 6.6e-172
PPNEOBKF_01543 4.7e-220 vex3 V ABC transporter permease
PPNEOBKF_01544 3.2e-212 vex1 V Efflux ABC transporter, permease protein
PPNEOBKF_01545 1.3e-111 vex2 V ABC transporter, ATP-binding protein
PPNEOBKF_01546 9.4e-23 azlD E Branched-chain amino acid transport protein (AzlD)
PPNEOBKF_01547 2.2e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
PPNEOBKF_01548 6.2e-96 ptpA 3.1.3.48 T low molecular weight
PPNEOBKF_01549 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
PPNEOBKF_01550 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PPNEOBKF_01551 8.5e-72 attW O OsmC-like protein
PPNEOBKF_01552 7.8e-191 T Universal stress protein family
PPNEOBKF_01553 1.7e-105 M NlpC/P60 family
PPNEOBKF_01554 9.1e-176 usp 3.5.1.28 CBM50 S CHAP domain
PPNEOBKF_01555 8.5e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PPNEOBKF_01556 2.6e-39
PPNEOBKF_01557 2.3e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PPNEOBKF_01558 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
PPNEOBKF_01559 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PPNEOBKF_01560 4.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
PPNEOBKF_01561 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PPNEOBKF_01563 1.2e-216 araJ EGP Major facilitator Superfamily
PPNEOBKF_01564 0.0 S Domain of unknown function (DUF4037)
PPNEOBKF_01565 4.3e-112 S Protein of unknown function (DUF4125)
PPNEOBKF_01566 2.1e-129
PPNEOBKF_01567 1.9e-290 pspC KT PspC domain
PPNEOBKF_01568 8.9e-273 tcsS3 KT PspC domain
PPNEOBKF_01569 9.2e-126 degU K helix_turn_helix, Lux Regulon
PPNEOBKF_01570 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PPNEOBKF_01572 6e-143 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
PPNEOBKF_01573 7.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
PPNEOBKF_01574 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PPNEOBKF_01575 1.2e-94
PPNEOBKF_01577 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
PPNEOBKF_01579 3.8e-238 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PPNEOBKF_01580 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
PPNEOBKF_01581 5.1e-212 I Diacylglycerol kinase catalytic domain
PPNEOBKF_01582 1.3e-151 arbG K CAT RNA binding domain
PPNEOBKF_01583 0.0 crr G pts system, glucose-specific IIABC component
PPNEOBKF_01584 4.4e-42 M Spy0128-like isopeptide containing domain
PPNEOBKF_01585 2.7e-43 M Spy0128-like isopeptide containing domain
PPNEOBKF_01586 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
PPNEOBKF_01587 4.4e-261 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PPNEOBKF_01588 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
PPNEOBKF_01589 3.8e-204 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PPNEOBKF_01590 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PPNEOBKF_01592 1.2e-106
PPNEOBKF_01593 6.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PPNEOBKF_01594 6.9e-234 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
PPNEOBKF_01595 1.6e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PPNEOBKF_01596 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PPNEOBKF_01597 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PPNEOBKF_01598 2.8e-188 nusA K Participates in both transcription termination and antitermination
PPNEOBKF_01599 1.6e-161
PPNEOBKF_01600 1.1e-145 L Transposase and inactivated derivatives
PPNEOBKF_01602 1.3e-153 E Transglutaminase/protease-like homologues
PPNEOBKF_01603 0.0 gcs2 S A circularly permuted ATPgrasp
PPNEOBKF_01604 3.2e-172 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PPNEOBKF_01605 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
PPNEOBKF_01606 8.1e-64 rplQ J Ribosomal protein L17
PPNEOBKF_01607 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PPNEOBKF_01608 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PPNEOBKF_01609 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PPNEOBKF_01610 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PPNEOBKF_01611 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PPNEOBKF_01612 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PPNEOBKF_01613 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PPNEOBKF_01614 2.7e-63 rplO J binds to the 23S rRNA
PPNEOBKF_01615 1e-24 rpmD J Ribosomal protein L30p/L7e
PPNEOBKF_01616 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PPNEOBKF_01617 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PPNEOBKF_01618 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PPNEOBKF_01619 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PPNEOBKF_01620 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PPNEOBKF_01621 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PPNEOBKF_01622 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PPNEOBKF_01623 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PPNEOBKF_01624 2.2e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PPNEOBKF_01625 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
PPNEOBKF_01626 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PPNEOBKF_01627 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PPNEOBKF_01628 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PPNEOBKF_01629 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PPNEOBKF_01630 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PPNEOBKF_01631 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PPNEOBKF_01632 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
PPNEOBKF_01633 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PPNEOBKF_01634 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
PPNEOBKF_01635 1.4e-58 ywiC S YwiC-like protein
PPNEOBKF_01636 9.7e-90 ywiC S YwiC-like protein
PPNEOBKF_01637 6.2e-157 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
PPNEOBKF_01638 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PPNEOBKF_01639 6.9e-231 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
PPNEOBKF_01640 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
PPNEOBKF_01641 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
PPNEOBKF_01642 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PPNEOBKF_01643 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
PPNEOBKF_01644 8.9e-112
PPNEOBKF_01645 1.1e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
PPNEOBKF_01646 3.6e-257 M Bacterial capsule synthesis protein PGA_cap
PPNEOBKF_01648 6e-241 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PPNEOBKF_01649 1.4e-225 dapC E Aminotransferase class I and II
PPNEOBKF_01650 9e-61 fdxA C 4Fe-4S binding domain
PPNEOBKF_01651 9.7e-217 murB 1.3.1.98 M Cell wall formation
PPNEOBKF_01652 1.9e-25 rpmG J Ribosomal protein L33
PPNEOBKF_01656 3.4e-56 KLT Associated with various cellular activities
PPNEOBKF_01657 3.1e-128 bla1 3.5.2.6 V Beta-lactamase enzyme family
PPNEOBKF_01658 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PPNEOBKF_01659 7.2e-144
PPNEOBKF_01660 2.3e-149 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
PPNEOBKF_01661 2e-120 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
PPNEOBKF_01662 3.2e-38 fmdB S Putative regulatory protein
PPNEOBKF_01663 1.6e-109 flgA NO SAF
PPNEOBKF_01664 9.6e-42
PPNEOBKF_01665 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
PPNEOBKF_01666 1e-237 T Forkhead associated domain
PPNEOBKF_01668 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PPNEOBKF_01669 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PPNEOBKF_01670 1.7e-182 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
PPNEOBKF_01671 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
PPNEOBKF_01673 8.8e-222 pbuO S Permease family
PPNEOBKF_01674 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
PPNEOBKF_01675 3e-170 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
PPNEOBKF_01676 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PPNEOBKF_01677 6.2e-180 pstA P Phosphate transport system permease
PPNEOBKF_01678 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
PPNEOBKF_01679 3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
PPNEOBKF_01680 1.4e-127 KT Transcriptional regulatory protein, C terminal
PPNEOBKF_01681 8.5e-246 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
PPNEOBKF_01682 1.9e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PPNEOBKF_01683 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PPNEOBKF_01684 9.7e-109 K helix_turn_helix, Arsenical Resistance Operon Repressor
PPNEOBKF_01685 3.4e-242 EGP Major facilitator Superfamily
PPNEOBKF_01686 3.3e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PPNEOBKF_01687 2.3e-166 L Excalibur calcium-binding domain
PPNEOBKF_01688 1.6e-268 pepC 3.4.22.40 E Peptidase C1-like family
PPNEOBKF_01689 7.4e-54 D nuclear chromosome segregation
PPNEOBKF_01690 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PPNEOBKF_01691 1.1e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PPNEOBKF_01692 1.6e-185 yfiH Q Multi-copper polyphenol oxidoreductase laccase
PPNEOBKF_01693 0.0 yegQ O Peptidase family U32 C-terminal domain
PPNEOBKF_01694 1.7e-96 L Transposase and inactivated derivatives IS30 family
PPNEOBKF_01695 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
PPNEOBKF_01696 6.3e-41 nrdH O Glutaredoxin
PPNEOBKF_01697 5.6e-98 nrdI F Probably involved in ribonucleotide reductase function
PPNEOBKF_01698 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PPNEOBKF_01699 9.1e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PPNEOBKF_01700 9.2e-74 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PPNEOBKF_01701 0.0 S Predicted membrane protein (DUF2207)
PPNEOBKF_01702 1.4e-93 lemA S LemA family
PPNEOBKF_01703 1.5e-40 K purine nucleotide biosynthetic process
PPNEOBKF_01704 2.6e-151 xylR K purine nucleotide biosynthetic process
PPNEOBKF_01705 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PPNEOBKF_01706 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PPNEOBKF_01707 8.9e-119
PPNEOBKF_01708 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
PPNEOBKF_01710 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
PPNEOBKF_01711 3.2e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PPNEOBKF_01712 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
PPNEOBKF_01713 7.2e-308 pccB I Carboxyl transferase domain
PPNEOBKF_01714 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
PPNEOBKF_01715 4.2e-93 bioY S BioY family
PPNEOBKF_01716 4e-153 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
PPNEOBKF_01717 0.0
PPNEOBKF_01718 5.9e-146 QT PucR C-terminal helix-turn-helix domain
PPNEOBKF_01719 9.5e-132 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
PPNEOBKF_01720 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PPNEOBKF_01721 9.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PPNEOBKF_01722 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PPNEOBKF_01723 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PPNEOBKF_01724 4.1e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PPNEOBKF_01725 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PPNEOBKF_01726 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PPNEOBKF_01728 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
PPNEOBKF_01729 1.2e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PPNEOBKF_01731 1e-44
PPNEOBKF_01732 0.0 K RNA polymerase II activating transcription factor binding
PPNEOBKF_01733 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
PPNEOBKF_01734 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PPNEOBKF_01737 1.3e-102 mntP P Probably functions as a manganese efflux pump
PPNEOBKF_01738 1.4e-125
PPNEOBKF_01739 1.8e-133 KT Transcriptional regulatory protein, C terminal
PPNEOBKF_01740 1.5e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PPNEOBKF_01741 4.3e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
PPNEOBKF_01742 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PPNEOBKF_01743 0.0 S domain protein
PPNEOBKF_01744 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
PPNEOBKF_01745 9.1e-90 lrp_3 K helix_turn_helix ASNC type
PPNEOBKF_01746 7.2e-236 E Aminotransferase class I and II
PPNEOBKF_01747 0.0 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PPNEOBKF_01748 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
PPNEOBKF_01749 2.5e-52 S Protein of unknown function (DUF2469)
PPNEOBKF_01750 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
PPNEOBKF_01751 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PPNEOBKF_01752 1.1e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PPNEOBKF_01753 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PPNEOBKF_01754 3.7e-82 V ABC transporter
PPNEOBKF_01755 1e-60 V ABC transporter
PPNEOBKF_01756 5.9e-155 spoU 2.1.1.185 J RNA methyltransferase TrmH family
PPNEOBKF_01757 1.6e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PPNEOBKF_01758 2.9e-214 rmuC S RmuC family
PPNEOBKF_01759 9.6e-43 csoR S Metal-sensitive transcriptional repressor
PPNEOBKF_01760 0.0 pacS 3.6.3.54 P E1-E2 ATPase
PPNEOBKF_01761 0.0 ubiB S ABC1 family
PPNEOBKF_01762 3.5e-19 S granule-associated protein
PPNEOBKF_01763 7.5e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
PPNEOBKF_01764 2.5e-281 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
PPNEOBKF_01765 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PPNEOBKF_01766 3.5e-250 dinF V MatE
PPNEOBKF_01767 3.5e-20 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
PPNEOBKF_01768 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
PPNEOBKF_01769 1e-54 glnB K Nitrogen regulatory protein P-II
PPNEOBKF_01770 3.8e-219 amt U Ammonium Transporter Family
PPNEOBKF_01771 6.2e-203 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PPNEOBKF_01773 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
PPNEOBKF_01774 1.5e-197 XK27_01805 M Glycosyltransferase like family 2
PPNEOBKF_01775 0.0 S Glycosyl hydrolases related to GH101 family, GH129
PPNEOBKF_01776 8.4e-306 pepD E Peptidase family C69
PPNEOBKF_01778 2.9e-19 XK26_04485 P Cobalt transport protein
PPNEOBKF_01779 1.1e-68 XK26_04485 P Cobalt transport protein
PPNEOBKF_01780 2e-82
PPNEOBKF_01781 0.0 V ABC transporter transmembrane region
PPNEOBKF_01782 1.8e-301 V ABC transporter, ATP-binding protein
PPNEOBKF_01783 2.7e-82 K Winged helix DNA-binding domain
PPNEOBKF_01784 5.8e-305 M LPXTG cell wall anchor motif
PPNEOBKF_01785 0.0 M chlorophyll binding
PPNEOBKF_01786 2e-180 3.4.22.70 M Sortase family
PPNEOBKF_01788 4.7e-162 S Sucrose-6F-phosphate phosphohydrolase
PPNEOBKF_01789 3.5e-241 S Putative ABC-transporter type IV
PPNEOBKF_01790 7e-81
PPNEOBKF_01791 5.8e-33 Q phosphatase activity
PPNEOBKF_01792 1.2e-295 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
PPNEOBKF_01793 3.3e-42 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
PPNEOBKF_01794 1.2e-48 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PPNEOBKF_01795 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PPNEOBKF_01796 4.6e-67 S haloacid dehalogenase-like hydrolase
PPNEOBKF_01797 1.4e-130 yydK K UTRA
PPNEOBKF_01798 1.3e-70 S FMN_bind
PPNEOBKF_01799 1.8e-147 macB V ABC transporter, ATP-binding protein
PPNEOBKF_01800 5.9e-204 Z012_06715 V FtsX-like permease family
PPNEOBKF_01801 9.7e-223 macB_2 V ABC transporter permease
PPNEOBKF_01802 1.6e-233 S Predicted membrane protein (DUF2318)
PPNEOBKF_01803 5.4e-108 tpd P Fe2+ transport protein
PPNEOBKF_01804 3.9e-307 efeU_1 P Iron permease FTR1 family
PPNEOBKF_01805 2e-18 G MFS/sugar transport protein
PPNEOBKF_01806 1.1e-200 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PPNEOBKF_01807 2e-56 S Fic/DOC family
PPNEOBKF_01808 1.2e-289 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PPNEOBKF_01809 5e-38 ptsH G PTS HPr component phosphorylation site
PPNEOBKF_01810 4.4e-200 K helix_turn _helix lactose operon repressor
PPNEOBKF_01811 6.3e-213 holB 2.7.7.7 L DNA polymerase III
PPNEOBKF_01812 1.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PPNEOBKF_01813 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PPNEOBKF_01814 6.4e-183 3.6.1.27 I PAP2 superfamily
PPNEOBKF_01815 0.0 vpr M PA domain
PPNEOBKF_01816 3e-122 yplQ S Haemolysin-III related
PPNEOBKF_01817 4.6e-232 glf 5.4.99.9 M UDP-galactopyranose mutase
PPNEOBKF_01818 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
PPNEOBKF_01819 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PPNEOBKF_01820 3.9e-278 S Calcineurin-like phosphoesterase
PPNEOBKF_01821 4.3e-14 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
PPNEOBKF_01822 1.2e-288 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
PPNEOBKF_01823 1.7e-116
PPNEOBKF_01824 1.1e-211 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PPNEOBKF_01826 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
PPNEOBKF_01827 1.8e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
PPNEOBKF_01828 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PPNEOBKF_01829 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
PPNEOBKF_01830 3.2e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
PPNEOBKF_01831 2e-56 S TIGRFAM helicase secretion neighborhood TadE-like protein
PPNEOBKF_01832 1.9e-41 S Protein of unknown function (DUF4244)
PPNEOBKF_01833 3.2e-15 gspF NU Type II secretion system (T2SS), protein F
PPNEOBKF_01834 1.4e-14 gspF NU Type II secretion system (T2SS), protein F
PPNEOBKF_01835 7.4e-121 U Type ii secretion system
PPNEOBKF_01836 3.4e-191 cpaF U Type II IV secretion system protein
PPNEOBKF_01837 7.5e-152 cpaE D bacterial-type flagellum organization
PPNEOBKF_01839 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PPNEOBKF_01840 5.1e-220 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
PPNEOBKF_01841 3.3e-90
PPNEOBKF_01842 2.1e-42 cbiM P PDGLE domain
PPNEOBKF_01843 2.2e-57 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PPNEOBKF_01844 2.5e-208 S Glycosyltransferase, group 2 family protein
PPNEOBKF_01845 5.2e-262
PPNEOBKF_01847 8.7e-27 thiS 2.8.1.10 H ThiS family
PPNEOBKF_01848 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PPNEOBKF_01849 0.0 S Psort location Cytoplasmic, score 8.87
PPNEOBKF_01850 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
PPNEOBKF_01851 1.1e-246 V ABC transporter permease
PPNEOBKF_01852 1.1e-181 V ABC transporter
PPNEOBKF_01853 2.1e-137 T HD domain
PPNEOBKF_01854 3.3e-166 S Glutamine amidotransferase domain
PPNEOBKF_01855 0.0 kup P Transport of potassium into the cell
PPNEOBKF_01856 1.3e-184 tatD L TatD related DNase
PPNEOBKF_01857 4.2e-275 xylR 5.3.1.12 G MFS/sugar transport protein
PPNEOBKF_01859 8.9e-87 K Transcriptional regulator
PPNEOBKF_01860 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PPNEOBKF_01861 3.6e-130
PPNEOBKF_01862 8.6e-59
PPNEOBKF_01863 4.6e-172 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PPNEOBKF_01864 2.7e-126 dedA S SNARE associated Golgi protein
PPNEOBKF_01866 3.5e-134 S HAD hydrolase, family IA, variant 3
PPNEOBKF_01867 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
PPNEOBKF_01868 1.8e-230 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
PPNEOBKF_01869 1.1e-186 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
PPNEOBKF_01870 2.6e-86 hspR K transcriptional regulator, MerR family
PPNEOBKF_01871 7.1e-173 dnaJ1 O DnaJ molecular chaperone homology domain
PPNEOBKF_01873 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PPNEOBKF_01874 0.0 dnaK O Heat shock 70 kDa protein
PPNEOBKF_01875 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
PPNEOBKF_01876 2.9e-190 K Psort location Cytoplasmic, score
PPNEOBKF_01879 1.8e-138 G Phosphoglycerate mutase family
PPNEOBKF_01880 3e-69 S Protein of unknown function (DUF4235)
PPNEOBKF_01881 1.2e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
PPNEOBKF_01882 1.1e-45

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)