ORF_ID e_value Gene_name EC_number CAZy COGs Description
IGHPPKDA_00001 3.4e-79
IGHPPKDA_00004 5.6e-92
IGHPPKDA_00005 5.4e-22
IGHPPKDA_00009 3.9e-71
IGHPPKDA_00010 1.1e-209 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IGHPPKDA_00011 2.1e-60 L hmm pf00665
IGHPPKDA_00012 6.3e-154 L 4.5 Transposon and IS
IGHPPKDA_00014 2.5e-36 L Transposase, IS116 IS110 IS902 family
IGHPPKDA_00039 7.2e-101 lacT K PRD domain
IGHPPKDA_00040 1.5e-62 lacE 2.7.1.207 G Phosphotransferase system, EIIC
IGHPPKDA_00041 1.6e-79 L Psort location Cytoplasmic, score
IGHPPKDA_00042 5.3e-120 L MobA MobL family protein
IGHPPKDA_00043 2.2e-52 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IGHPPKDA_00044 3e-69 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IGHPPKDA_00046 7.1e-32 eno 4.2.1.11 G phosphopyruvate hydratase activity
IGHPPKDA_00048 1.4e-137 3.1.1.32, 3.1.1.4 S COG0790 FOG TPR repeat, SEL1 subfamily
IGHPPKDA_00049 8.6e-71
IGHPPKDA_00050 2.6e-160 glf 5.4.99.9 M UDP-galactopyranose mutase
IGHPPKDA_00051 4.2e-95 M Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IGHPPKDA_00052 6.3e-218 N domain, Protein
IGHPPKDA_00053 2.6e-285 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IGHPPKDA_00054 0.0 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IGHPPKDA_00055 1.8e-150 licT2 K CAT RNA binding domain
IGHPPKDA_00056 0.0 S Bacterial membrane protein YfhO
IGHPPKDA_00057 0.0 S Psort location CytoplasmicMembrane, score
IGHPPKDA_00058 2e-169 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
IGHPPKDA_00059 2.8e-74
IGHPPKDA_00060 6.6e-168 yqjA S Putative aromatic acid exporter C-terminal domain
IGHPPKDA_00061 1.6e-31 cspC K Cold shock protein
IGHPPKDA_00062 8.6e-84 yvbK 3.1.3.25 K GNAT family
IGHPPKDA_00063 1.9e-115 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
IGHPPKDA_00064 8e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IGHPPKDA_00065 6.8e-240 pbuX F xanthine permease
IGHPPKDA_00066 1.5e-203 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IGHPPKDA_00067 5.3e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IGHPPKDA_00068 2.8e-105
IGHPPKDA_00069 1.8e-104
IGHPPKDA_00070 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IGHPPKDA_00071 5.2e-110 vanZ V VanZ like family
IGHPPKDA_00072 2e-152 glcU U sugar transport
IGHPPKDA_00073 5.6e-258 pgi 5.3.1.9 G Belongs to the GPI family
IGHPPKDA_00074 2.3e-66 S Domain of unknown function DUF1829
IGHPPKDA_00075 4.4e-49 S Domain of unknown function DUF1829
IGHPPKDA_00076 9.5e-46 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
IGHPPKDA_00078 5e-151 F DNA/RNA non-specific endonuclease
IGHPPKDA_00079 1.7e-70 yttA 2.7.13.3 S Pfam Transposase IS66
IGHPPKDA_00080 7.3e-230 wbbX GT2,GT4 M Glycosyl transferases group 1
IGHPPKDA_00081 5e-173 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
IGHPPKDA_00082 9.9e-85 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
IGHPPKDA_00084 7.6e-80 tspO T TspO/MBR family
IGHPPKDA_00085 3.2e-13
IGHPPKDA_00086 7.8e-211 yttB EGP Major facilitator Superfamily
IGHPPKDA_00087 1.9e-104 S Protein of unknown function (DUF1211)
IGHPPKDA_00088 1.2e-285 pipD E Dipeptidase
IGHPPKDA_00090 1.6e-07
IGHPPKDA_00091 4.2e-127 G Phosphoglycerate mutase family
IGHPPKDA_00092 2.6e-120 K Bacterial regulatory proteins, tetR family
IGHPPKDA_00093 0.0 ycfI V ABC transporter, ATP-binding protein
IGHPPKDA_00094 0.0 yfiC V ABC transporter
IGHPPKDA_00095 3.5e-140 S NADPH-dependent FMN reductase
IGHPPKDA_00096 1.7e-162 1.13.11.2 S glyoxalase
IGHPPKDA_00097 2.7e-196 ampC V Beta-lactamase
IGHPPKDA_00098 1.9e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
IGHPPKDA_00099 3.5e-111 tdk 2.7.1.21 F thymidine kinase
IGHPPKDA_00100 1.9e-176 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IGHPPKDA_00101 4.4e-152 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IGHPPKDA_00102 6.2e-185 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IGHPPKDA_00103 1.2e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IGHPPKDA_00104 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IGHPPKDA_00105 4.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
IGHPPKDA_00106 3.3e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IGHPPKDA_00107 2.7e-40 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IGHPPKDA_00108 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IGHPPKDA_00109 9.5e-286 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IGHPPKDA_00110 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IGHPPKDA_00111 1.1e-243 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IGHPPKDA_00112 8.3e-70 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IGHPPKDA_00113 9.3e-31 ywzB S Protein of unknown function (DUF1146)
IGHPPKDA_00114 1.1e-178 mbl D Cell shape determining protein MreB Mrl
IGHPPKDA_00115 2.2e-18 epuA S DNA-directed RNA polymerase subunit beta
IGHPPKDA_00116 9.1e-55 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IGHPPKDA_00117 1.1e-30 S Protein of unknown function (DUF2969)
IGHPPKDA_00118 1.8e-223 rodA D Belongs to the SEDS family
IGHPPKDA_00119 2.1e-48 gcvH E glycine cleavage
IGHPPKDA_00120 2.6e-115 L Resolvase, N terminal domain
IGHPPKDA_00121 3.8e-63 S Protein of unknown function (DUF1093)
IGHPPKDA_00123 2.7e-293 L Transposase IS66 family
IGHPPKDA_00124 1.8e-62 L IS66 Orf2 like protein
IGHPPKDA_00125 4e-27
IGHPPKDA_00128 6.4e-219 3.1.1.32, 3.1.1.4 S COG0790 FOG TPR repeat, SEL1 subfamily
IGHPPKDA_00130 2.9e-58 L Initiator Replication protein
IGHPPKDA_00131 1.3e-106
IGHPPKDA_00132 3.9e-197 S ABC-type transport system involved in multi-copper enzyme maturation permease component
IGHPPKDA_00133 1.7e-133 F DNA/RNA non-specific endonuclease
IGHPPKDA_00135 2.8e-29 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IGHPPKDA_00136 1.2e-85 yjdB S Domain of unknown function (DUF4767)
IGHPPKDA_00137 4.6e-73 lctO C IMP dehydrogenase / GMP reductase domain
IGHPPKDA_00138 2.3e-33 sip L Belongs to the 'phage' integrase family
IGHPPKDA_00139 2.3e-93 XK27_08455 G PTS system sorbose-specific iic component
IGHPPKDA_00140 7.9e-146 manZ_1 G PTS system mannose/fructose/sorbose family IID component
IGHPPKDA_00141 1.4e-121 yhgE V domain protein
IGHPPKDA_00142 7.2e-80 yobS K Bacterial regulatory proteins, tetR family
IGHPPKDA_00143 2.5e-26
IGHPPKDA_00145 2.5e-23
IGHPPKDA_00146 1.1e-19
IGHPPKDA_00147 2.3e-11
IGHPPKDA_00148 1.3e-182 ytxK 2.1.1.72 L N-6 DNA Methylase
IGHPPKDA_00149 4.1e-51
IGHPPKDA_00150 2.4e-256 cycA E Amino acid permease
IGHPPKDA_00151 1.3e-147 arbV 2.3.1.51 I Phosphate acyltransferases
IGHPPKDA_00152 2.5e-163 arbx M Glycosyl transferase family 8
IGHPPKDA_00153 2.3e-181 arbY M family 8
IGHPPKDA_00154 2.8e-165 arbZ I Phosphate acyltransferases
IGHPPKDA_00155 0.0 rafA 3.2.1.22 G alpha-galactosidase
IGHPPKDA_00158 5.8e-70 S SdpI/YhfL protein family
IGHPPKDA_00159 2.1e-134 K response regulator
IGHPPKDA_00160 5.7e-272 T PhoQ Sensor
IGHPPKDA_00161 6.2e-75 yhbS S acetyltransferase
IGHPPKDA_00162 5.3e-14
IGHPPKDA_00163 1.5e-71 pheB 5.4.99.5 S Belongs to the UPF0735 family
IGHPPKDA_00164 1e-63
IGHPPKDA_00165 1.3e-54
IGHPPKDA_00166 3.1e-253 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
IGHPPKDA_00168 2e-190 S response to antibiotic
IGHPPKDA_00169 1.3e-129 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
IGHPPKDA_00170 8.4e-27 yjgN S Bacterial protein of unknown function (DUF898)
IGHPPKDA_00172 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IGHPPKDA_00173 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IGHPPKDA_00174 5.2e-212 camS S sex pheromone
IGHPPKDA_00175 3.7e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IGHPPKDA_00176 1e-265 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IGHPPKDA_00177 8e-279 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IGHPPKDA_00178 4.4e-194 yegS 2.7.1.107 G Lipid kinase
IGHPPKDA_00179 7.4e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IGHPPKDA_00180 3.6e-219 yttB EGP Major facilitator Superfamily
IGHPPKDA_00181 1.8e-145 cof S Sucrose-6F-phosphate phosphohydrolase
IGHPPKDA_00182 1.5e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
IGHPPKDA_00183 0.0 pepO 3.4.24.71 O Peptidase family M13
IGHPPKDA_00184 5e-265 ydiC1 EGP Major facilitator Superfamily
IGHPPKDA_00185 1.3e-78 K Acetyltransferase (GNAT) family
IGHPPKDA_00186 4.3e-166 degV S Uncharacterised protein, DegV family COG1307
IGHPPKDA_00187 1.9e-119 qmcA O prohibitin homologues
IGHPPKDA_00188 1.2e-28
IGHPPKDA_00189 3.9e-136 lys M Glycosyl hydrolases family 25
IGHPPKDA_00190 2.2e-60 S Protein of unknown function (DUF1093)
IGHPPKDA_00191 1.7e-60 S Domain of unknown function (DUF4828)
IGHPPKDA_00192 1.9e-175 mocA S Oxidoreductase
IGHPPKDA_00193 7.3e-223 yfmL 3.6.4.13 L DEAD DEAH box helicase
IGHPPKDA_00194 3.4e-56 chbA 2.7.1.196, 2.7.1.205 G phosphoenolpyruvate-dependent sugar phosphotransferase system
IGHPPKDA_00195 9.6e-71 S Domain of unknown function (DUF3284)
IGHPPKDA_00197 1.7e-06
IGHPPKDA_00198 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IGHPPKDA_00199 5.9e-238 pepS E Thermophilic metalloprotease (M29)
IGHPPKDA_00200 9.4e-112 K Bacterial regulatory proteins, tetR family
IGHPPKDA_00202 7.5e-258 S Uncharacterized protein conserved in bacteria (DUF2252)
IGHPPKDA_00203 6e-180 yihY S Belongs to the UPF0761 family
IGHPPKDA_00204 7.2e-80 fld C Flavodoxin
IGHPPKDA_00205 4.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
IGHPPKDA_00206 2.9e-201 M Glycosyltransferase like family 2
IGHPPKDA_00208 3.1e-14
IGHPPKDA_00209 1.8e-198 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IGHPPKDA_00210 1.9e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IGHPPKDA_00212 4.1e-163 eps4I GM Male sterility protein
IGHPPKDA_00213 3.6e-99 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
IGHPPKDA_00214 2.8e-221 L Transposase
IGHPPKDA_00215 7.3e-21 S Protease prsW family
IGHPPKDA_00216 2e-95 L Resolvase, N terminal domain
IGHPPKDA_00217 5.5e-51 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
IGHPPKDA_00218 1.1e-121 drgA C Nitroreductase family
IGHPPKDA_00219 1.2e-68 lctO C IMP dehydrogenase / GMP reductase domain
IGHPPKDA_00220 1.1e-30 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
IGHPPKDA_00221 3.7e-111 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
IGHPPKDA_00222 1.5e-83 gutM K Glucitol operon activator protein (GutM)
IGHPPKDA_00223 5.4e-38 L Phage terminase, small subunit
IGHPPKDA_00224 6.6e-39 L HNH nucleases
IGHPPKDA_00225 1.8e-26
IGHPPKDA_00226 7.4e-164 S DUF218 domain
IGHPPKDA_00228 1.7e-46 K Bacterial regulatory proteins, tetR family
IGHPPKDA_00229 1.4e-21 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_00230 8.4e-30 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IGHPPKDA_00231 4.8e-32 M transferase activity, transferring glycosyl groups
IGHPPKDA_00232 4.2e-164 corA P CorA-like Mg2+ transporter protein
IGHPPKDA_00233 1.3e-43
IGHPPKDA_00234 8.4e-218 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IGHPPKDA_00235 2.8e-177 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGHPPKDA_00236 2.5e-173 pfoS S Phosphotransferase system, EIIC
IGHPPKDA_00237 3.9e-39
IGHPPKDA_00238 6.5e-170 yqiK S SPFH domain / Band 7 family
IGHPPKDA_00239 1.8e-248 yclM 2.7.2.4 E Belongs to the aspartokinase family
IGHPPKDA_00240 6.4e-229 hom 1.1.1.3 E homoserine dehydrogenase
IGHPPKDA_00241 4.7e-285 thrC 4.2.3.1 E Threonine synthase
IGHPPKDA_00242 1.3e-130 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IGHPPKDA_00243 1.5e-252 yxbA 6.3.1.12 S ATP-grasp enzyme
IGHPPKDA_00244 2.4e-67 usp1 T Universal stress protein family
IGHPPKDA_00245 2.1e-137 sfsA S Belongs to the SfsA family
IGHPPKDA_00246 1.7e-221 gbuA 3.6.3.32 E glycine betaine
IGHPPKDA_00247 1.1e-147 proW E glycine betaine
IGHPPKDA_00248 4e-167 gbuC E glycine betaine
IGHPPKDA_00249 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IGHPPKDA_00250 1.4e-175 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IGHPPKDA_00251 1.3e-64 gtcA S Teichoic acid glycosylation protein
IGHPPKDA_00253 1.3e-128 srtA 3.4.22.70 M Sortase family
IGHPPKDA_00254 7.1e-187 K AI-2E family transporter
IGHPPKDA_00255 8.5e-204 pbpX1 V Beta-lactamase
IGHPPKDA_00256 8.8e-121 S zinc-ribbon domain
IGHPPKDA_00257 3.4e-21
IGHPPKDA_00258 3.9e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IGHPPKDA_00259 1.6e-82 F NUDIX domain
IGHPPKDA_00260 0.0 lmrA 3.6.3.44 V ABC transporter
IGHPPKDA_00261 2.7e-103 rmaB K Transcriptional regulator, MarR family
IGHPPKDA_00262 1.7e-196
IGHPPKDA_00263 1.6e-164 S Putative esterase
IGHPPKDA_00264 1.3e-12 S response to antibiotic
IGHPPKDA_00265 1.4e-66 K MarR family
IGHPPKDA_00266 1.4e-47 S Uncharacterized protein conserved in bacteria (DUF2316)
IGHPPKDA_00267 2.3e-226 bdhA C Iron-containing alcohol dehydrogenase
IGHPPKDA_00268 6.7e-192 bioH 2.1.1.197, 3.1.1.85, 3.7.1.13, 3.7.1.9, 4.2.99.20 E Alpha/beta hydrolase family
IGHPPKDA_00269 3.1e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IGHPPKDA_00270 6.2e-76 marR K Winged helix DNA-binding domain
IGHPPKDA_00271 3e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IGHPPKDA_00272 1.2e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IGHPPKDA_00273 8.2e-174 fabK 1.3.1.9 S Nitronate monooxygenase
IGHPPKDA_00274 1.4e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IGHPPKDA_00275 6.8e-125 IQ reductase
IGHPPKDA_00276 1.4e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IGHPPKDA_00277 1.7e-62 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IGHPPKDA_00278 8.7e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IGHPPKDA_00279 3.7e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IGHPPKDA_00280 6.2e-151 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IGHPPKDA_00281 1.5e-141 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IGHPPKDA_00282 8.5e-234 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IGHPPKDA_00283 2e-85 azoB GM NmrA-like family
IGHPPKDA_00284 3.3e-304 scrB 3.2.1.26 GH32 G invertase
IGHPPKDA_00285 4.6e-180 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
IGHPPKDA_00286 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IGHPPKDA_00287 0.0 scrA 2.7.1.211 G phosphotransferase system
IGHPPKDA_00288 8.3e-213 ykiI
IGHPPKDA_00289 2e-146 IQ reductase
IGHPPKDA_00290 5.5e-173 ald 1.4.1.1 C Belongs to the AlaDH PNT family
IGHPPKDA_00291 2.3e-48 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_00292 3.7e-79 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IGHPPKDA_00293 1.1e-56 4.1.2.13 G Fructose-bisphosphate aldolase class-II
IGHPPKDA_00294 8.6e-136 L Helix-turn-helix domain
IGHPPKDA_00295 8e-51 L hmm pf00665
IGHPPKDA_00296 1e-23
IGHPPKDA_00297 4.4e-07
IGHPPKDA_00298 6.8e-48 lciIC K Helix-turn-helix XRE-family like proteins
IGHPPKDA_00299 6.1e-35
IGHPPKDA_00301 7.6e-67 L transposition
IGHPPKDA_00302 1.8e-183 M Bacterial Ig-like domain (group 3)
IGHPPKDA_00303 1.2e-109 S Phage Terminase
IGHPPKDA_00305 7.6e-11 yobS K Bacterial regulatory proteins, tetR family
IGHPPKDA_00306 1.3e-252 bmr3 EGP Major facilitator Superfamily
IGHPPKDA_00307 3.3e-33
IGHPPKDA_00308 1e-11
IGHPPKDA_00309 2.1e-53 V abc transporter atp-binding protein
IGHPPKDA_00312 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IGHPPKDA_00313 4.7e-299 oppA E ABC transporter, substratebinding protein
IGHPPKDA_00314 1.4e-83
IGHPPKDA_00315 2.6e-52
IGHPPKDA_00316 5.9e-68
IGHPPKDA_00317 5.6e-89 V ATPases associated with a variety of cellular activities
IGHPPKDA_00318 1.4e-41
IGHPPKDA_00319 1.3e-76 S NUDIX domain
IGHPPKDA_00320 2.9e-161 S nuclear-transcribed mRNA catabolic process, no-go decay
IGHPPKDA_00321 6.8e-113 V ABC transporter transmembrane region
IGHPPKDA_00322 9.6e-100 V ABC transporter transmembrane region
IGHPPKDA_00323 2.1e-112 gadR K Helix-turn-helix XRE-family like proteins
IGHPPKDA_00324 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
IGHPPKDA_00325 3.8e-262 nox 1.6.3.4 C NADH oxidase
IGHPPKDA_00326 1.7e-116
IGHPPKDA_00327 2.5e-218 S TPM domain
IGHPPKDA_00328 3.9e-124 yxaA S Sulfite exporter TauE/SafE
IGHPPKDA_00329 5e-55 ywjH S Protein of unknown function (DUF1634)
IGHPPKDA_00331 6.5e-90
IGHPPKDA_00332 2.8e-48
IGHPPKDA_00333 2.4e-83 fld C Flavodoxin
IGHPPKDA_00334 2.6e-36
IGHPPKDA_00335 1.1e-26
IGHPPKDA_00336 1.9e-170 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGHPPKDA_00337 3.1e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
IGHPPKDA_00338 9.9e-39 S Transglycosylase associated protein
IGHPPKDA_00339 1.2e-81 S Protein conserved in bacteria
IGHPPKDA_00340 2.8e-25
IGHPPKDA_00341 7.4e-68 asp23 S Asp23 family, cell envelope-related function
IGHPPKDA_00342 1.6e-62 asp2 S Asp23 family, cell envelope-related function
IGHPPKDA_00343 2.5e-113 S Protein of unknown function (DUF969)
IGHPPKDA_00344 6.6e-79 S Protein of unknown function (DUF979)
IGHPPKDA_00345 3.1e-54 S Protein of unknown function (DUF979)
IGHPPKDA_00346 5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IGHPPKDA_00347 6.5e-108 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IGHPPKDA_00348 5.1e-127 cobQ S glutamine amidotransferase
IGHPPKDA_00349 1.3e-66
IGHPPKDA_00350 3.2e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IGHPPKDA_00351 1.1e-142 noc K Belongs to the ParB family
IGHPPKDA_00352 9.7e-138 soj D Sporulation initiation inhibitor
IGHPPKDA_00353 5.2e-156 spo0J K Belongs to the ParB family
IGHPPKDA_00354 1.8e-29 yyzM S Bacterial protein of unknown function (DUF951)
IGHPPKDA_00355 1.3e-185 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IGHPPKDA_00356 2e-109 XK27_01040 S Protein of unknown function (DUF1129)
IGHPPKDA_00357 5.6e-275 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IGHPPKDA_00358 1.6e-120
IGHPPKDA_00359 3.3e-121 K response regulator
IGHPPKDA_00360 3.9e-218 hpk31 2.7.13.3 T Histidine kinase
IGHPPKDA_00361 1.8e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IGHPPKDA_00362 1.8e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IGHPPKDA_00363 4.3e-294 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IGHPPKDA_00364 7e-141 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
IGHPPKDA_00365 1e-164 yvgN C Aldo keto reductase
IGHPPKDA_00366 4.3e-123 gntR K rpiR family
IGHPPKDA_00367 1.1e-167 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
IGHPPKDA_00368 1.9e-305 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IGHPPKDA_00369 8.8e-211 gntP EG Gluconate
IGHPPKDA_00370 1.8e-58 M Cna protein B-type domain
IGHPPKDA_00371 1.9e-98 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
IGHPPKDA_00372 5.2e-72 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IGHPPKDA_00373 8e-129 G Phosphotransferase System
IGHPPKDA_00374 1.7e-110 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IGHPPKDA_00375 1e-37
IGHPPKDA_00376 5.9e-99 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IGHPPKDA_00377 2.3e-51 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
IGHPPKDA_00378 1.1e-155 K Sugar-specific transcriptional regulator TrmB
IGHPPKDA_00379 1.3e-187 tra L Transposase and inactivated derivatives, IS30 family
IGHPPKDA_00380 4.9e-41 yqkB S Iron-sulphur cluster biosynthesis
IGHPPKDA_00381 1.5e-129 S Protein of unknown function (DUF975)
IGHPPKDA_00382 2.3e-237 G Bacterial extracellular solute-binding protein
IGHPPKDA_00383 6.5e-30
IGHPPKDA_00384 3.1e-133 glnQ E ABC transporter, ATP-binding protein
IGHPPKDA_00385 3.1e-287 glnP P ABC transporter permease
IGHPPKDA_00387 7.3e-158 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_00388 2e-132 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_00389 9.4e-189 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_00391 1.1e-218 EGP Major facilitator Superfamily
IGHPPKDA_00392 2.4e-181 manL 2.7.1.191, 2.7.1.206 G PTS system sorbose subfamily IIB component
IGHPPKDA_00393 8.7e-121 manY G PTS system
IGHPPKDA_00394 2.5e-169 manN G system, mannose fructose sorbose family IID component
IGHPPKDA_00395 3.4e-64 manO S Domain of unknown function (DUF956)
IGHPPKDA_00396 2.5e-172 iolS C Aldo keto reductase
IGHPPKDA_00397 2.1e-211 yeaN P Transporter, major facilitator family protein
IGHPPKDA_00398 1.3e-161 ydiC1 EGP Major Facilitator Superfamily
IGHPPKDA_00399 1.9e-71 ydiC1 EGP Major Facilitator Superfamily
IGHPPKDA_00400 5.1e-113 ycaC Q Isochorismatase family
IGHPPKDA_00401 1.3e-88 S AAA domain
IGHPPKDA_00402 1.7e-84 F NUDIX domain
IGHPPKDA_00403 3.2e-100 speG J Acetyltransferase (GNAT) domain
IGHPPKDA_00404 2.4e-53 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
IGHPPKDA_00405 2.3e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_00406 1.5e-129 K UTRA
IGHPPKDA_00407 3.6e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGHPPKDA_00408 1.6e-73 S Domain of unknown function (DUF3284)
IGHPPKDA_00409 3.1e-214 S Bacterial protein of unknown function (DUF871)
IGHPPKDA_00410 2.4e-264 argH 4.3.2.1 E argininosuccinate lyase
IGHPPKDA_00411 1.7e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IGHPPKDA_00412 1.6e-258 arpJ P ABC transporter permease
IGHPPKDA_00413 1.5e-121 3.1.1.24 S Alpha/beta hydrolase family
IGHPPKDA_00414 1.1e-130 K response regulator
IGHPPKDA_00415 0.0 vicK 2.7.13.3 T Histidine kinase
IGHPPKDA_00416 3.3e-256 yycH S YycH protein
IGHPPKDA_00417 3.1e-139 yycI S YycH protein
IGHPPKDA_00418 7.8e-154 vicX 3.1.26.11 S domain protein
IGHPPKDA_00419 1.9e-210 htrA 3.4.21.107 O serine protease
IGHPPKDA_00420 2.7e-70 S Iron-sulphur cluster biosynthesis
IGHPPKDA_00421 6e-76 hsp3 O Belongs to the small heat shock protein (HSP20) family
IGHPPKDA_00422 0.0 cadA P P-type ATPase
IGHPPKDA_00423 3.4e-102
IGHPPKDA_00424 5.1e-298 E ABC transporter, substratebinding protein
IGHPPKDA_00425 1.2e-255 E Peptidase dimerisation domain
IGHPPKDA_00426 1.6e-69
IGHPPKDA_00427 4.1e-198 ybiR P Citrate transporter
IGHPPKDA_00428 1.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IGHPPKDA_00429 3.7e-76 2.3.1.82 K Acetyltransferase (GNAT) domain
IGHPPKDA_00430 9e-83 yiaC K Acetyltransferase (GNAT) domain
IGHPPKDA_00431 3.1e-87 K Acetyltransferase (GNAT) domain
IGHPPKDA_00432 3.9e-139 wzb 3.1.3.48 T Tyrosine phosphatase family
IGHPPKDA_00433 1.2e-52 1.1.1.1 C nadph quinone reductase
IGHPPKDA_00434 1.2e-126 1.1.1.1 C nadph quinone reductase
IGHPPKDA_00435 5.3e-47 hisB 2.7.7.71, 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19, 5.3.1.28, 6.3.2.10 GT9 E HAD-hyrolase-like
IGHPPKDA_00436 9.1e-76 S Short repeat of unknown function (DUF308)
IGHPPKDA_00437 3.3e-79 ydhK M Protein of unknown function (DUF1541)
IGHPPKDA_00439 1.7e-55 S HNH endonuclease
IGHPPKDA_00440 3e-48
IGHPPKDA_00442 1.4e-119 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IGHPPKDA_00443 9.5e-11 S Clp protease
IGHPPKDA_00446 1.3e-51 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphoenolpyruvate-dependent sugar phosphotransferase system
IGHPPKDA_00447 4.4e-86 V ABC transporter transmembrane region
IGHPPKDA_00448 1.4e-263 V ABC transporter transmembrane region
IGHPPKDA_00449 9.6e-37
IGHPPKDA_00450 3e-51 K Transcriptional
IGHPPKDA_00451 7.3e-129 hchA S DJ-1/PfpI family
IGHPPKDA_00452 3.3e-292 E Bacterial extracellular solute-binding proteins, family 5 Middle
IGHPPKDA_00453 5.5e-167 oppB P Binding-protein-dependent transport system inner membrane component
IGHPPKDA_00454 4.4e-175 amiD EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGHPPKDA_00455 8.5e-24
IGHPPKDA_00456 2.5e-200 oppD P Oligopeptide/dipeptide transporter, C-terminal region
IGHPPKDA_00457 1.9e-158 oppF P Oligopeptide/dipeptide transporter, C-terminal region
IGHPPKDA_00458 1.6e-102 ydaF J Acetyltransferase (GNAT) domain
IGHPPKDA_00459 1.4e-21
IGHPPKDA_00460 4.6e-126 skfE V ATPases associated with a variety of cellular activities
IGHPPKDA_00461 5.2e-60 yvoA_1 K Transcriptional regulator, GntR family
IGHPPKDA_00462 1.2e-160 S Alpha beta hydrolase
IGHPPKDA_00463 2.5e-181 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_00464 6.2e-126 S membrane transporter protein
IGHPPKDA_00465 5.9e-258 EGP Major facilitator Superfamily
IGHPPKDA_00466 9.6e-115 K Transcriptional regulator
IGHPPKDA_00467 7.9e-291 M Exporter of polyketide antibiotics
IGHPPKDA_00468 4.8e-168 yjjC V ABC transporter
IGHPPKDA_00469 4.7e-137 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IGHPPKDA_00470 6.2e-146 ORF00048
IGHPPKDA_00471 9.7e-58 K Transcriptional regulator PadR-like family
IGHPPKDA_00472 1.2e-106 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IGHPPKDA_00473 6.1e-85 K GNAT family
IGHPPKDA_00474 2.8e-102 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
IGHPPKDA_00475 2.8e-41
IGHPPKDA_00476 1.1e-240 citM C Citrate transporter
IGHPPKDA_00477 5.9e-52
IGHPPKDA_00478 1.8e-39 gcdC 2.3.1.12 I Biotin-requiring enzyme
IGHPPKDA_00479 3.9e-196 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
IGHPPKDA_00481 5.6e-178 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IGHPPKDA_00482 1.3e-48 citD C Covalent carrier of the coenzyme of citrate lyase
IGHPPKDA_00483 2.6e-155 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
IGHPPKDA_00484 1.7e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IGHPPKDA_00485 8.8e-93 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IGHPPKDA_00486 2.6e-266 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
IGHPPKDA_00487 8e-123 citR K FCD
IGHPPKDA_00488 1.7e-151 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IGHPPKDA_00489 9.3e-74
IGHPPKDA_00490 3.2e-32
IGHPPKDA_00491 9.8e-157 I alpha/beta hydrolase fold
IGHPPKDA_00492 1e-159 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IGHPPKDA_00493 4.9e-116 sodA 1.15.1.1 C Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IGHPPKDA_00494 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IGHPPKDA_00495 2e-87
IGHPPKDA_00496 1.9e-192 S Protein of unknown function C-terminal (DUF3324)
IGHPPKDA_00497 2.3e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
IGHPPKDA_00498 2e-97
IGHPPKDA_00499 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IGHPPKDA_00500 1.1e-130 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
IGHPPKDA_00502 6.7e-265 lysP E amino acid
IGHPPKDA_00503 2.6e-123 frvR K Mga helix-turn-helix domain
IGHPPKDA_00504 3.3e-147 frvR K Mga helix-turn-helix domain
IGHPPKDA_00505 4.7e-304 frvR K Mga helix-turn-helix domain
IGHPPKDA_00506 7.3e-223 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IGHPPKDA_00507 7.1e-31
IGHPPKDA_00509 3.2e-46 ligA 6.5.1.2 L BRCA1 C Terminus (BRCT) domain
IGHPPKDA_00510 1.6e-33 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
IGHPPKDA_00511 3.1e-110 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
IGHPPKDA_00512 1.6e-53 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
IGHPPKDA_00513 6.8e-127 tnp L DDE domain
IGHPPKDA_00514 5.6e-55
IGHPPKDA_00515 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IGHPPKDA_00516 9.9e-219 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IGHPPKDA_00517 3.2e-202 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
IGHPPKDA_00518 4.2e-209 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
IGHPPKDA_00519 1.6e-48
IGHPPKDA_00520 2.6e-160 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IGHPPKDA_00521 6.3e-102 V Restriction endonuclease
IGHPPKDA_00522 5.8e-157 5.1.3.3 G converts alpha-aldose to the beta-anomer
IGHPPKDA_00523 5.2e-212 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IGHPPKDA_00524 1e-102 S ECF transporter, substrate-specific component
IGHPPKDA_00526 2.1e-79 yodP 2.3.1.264 K Acetyltransferase GNAT Family
IGHPPKDA_00527 3.3e-85 ydcK S Belongs to the SprT family
IGHPPKDA_00528 1.9e-130 XK27_08845 S ABC transporter, ATP-binding protein
IGHPPKDA_00529 4.2e-140 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IGHPPKDA_00530 1.7e-155 XK27_08835 S ABC transporter
IGHPPKDA_00532 2.6e-71
IGHPPKDA_00533 0.0 pacL 3.6.3.8 P P-type ATPase
IGHPPKDA_00534 6e-216 V Beta-lactamase
IGHPPKDA_00535 7.6e-146 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IGHPPKDA_00536 3.5e-217 V Beta-lactamase
IGHPPKDA_00537 7.2e-275 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IGHPPKDA_00538 5e-125 gntR1 K UbiC transcription regulator-associated domain protein
IGHPPKDA_00539 2.6e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IGHPPKDA_00540 1.1e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IGHPPKDA_00541 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
IGHPPKDA_00544 5.3e-158 yjjH S Calcineurin-like phosphoesterase
IGHPPKDA_00545 1.7e-51 dtpT U amino acid peptide transporter
IGHPPKDA_00546 1.3e-196 dtpT U amino acid peptide transporter
IGHPPKDA_00547 0.0 macB_3 V ABC transporter, ATP-binding protein
IGHPPKDA_00548 3.1e-65
IGHPPKDA_00549 3.4e-76 S function, without similarity to other proteins
IGHPPKDA_00550 2.8e-263 G MFS/sugar transport protein
IGHPPKDA_00551 6.5e-231 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
IGHPPKDA_00552 2.7e-178 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IGHPPKDA_00553 5.4e-58
IGHPPKDA_00554 0.0 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
IGHPPKDA_00555 1.4e-17 S Virus attachment protein p12 family
IGHPPKDA_00556 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IGHPPKDA_00557 9.4e-70 feoA P FeoA
IGHPPKDA_00558 3.9e-123 E lipolytic protein G-D-S-L family
IGHPPKDA_00561 1.2e-117 ywnB S NAD(P)H-binding
IGHPPKDA_00562 9.9e-62 S MucBP domain
IGHPPKDA_00563 1.2e-62
IGHPPKDA_00567 3.8e-62 S calcium ion binding
IGHPPKDA_00569 8.1e-85 manR K PRD domain
IGHPPKDA_00570 6.3e-241 dinF V MatE
IGHPPKDA_00571 1.9e-110 S TPM domain
IGHPPKDA_00572 1e-102 lemA S LemA family
IGHPPKDA_00573 1.6e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IGHPPKDA_00574 2.2e-246 gshR 1.8.1.7 C Glutathione reductase
IGHPPKDA_00575 1.1e-175 proV E ABC transporter, ATP-binding protein
IGHPPKDA_00576 5.8e-275 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IGHPPKDA_00578 0.0 helD 3.6.4.12 L DNA helicase
IGHPPKDA_00579 5.9e-149 rlrG K Transcriptional regulator
IGHPPKDA_00580 4e-173 shetA P Voltage-dependent anion channel
IGHPPKDA_00581 4.1e-113 S CAAX protease self-immunity
IGHPPKDA_00583 2.7e-115 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IGHPPKDA_00584 5.2e-69 K MarR family
IGHPPKDA_00585 0.0 uvrA3 L excinuclease ABC
IGHPPKDA_00586 8.1e-193 yghZ C Aldo keto reductase family protein
IGHPPKDA_00587 3e-145 S hydrolase
IGHPPKDA_00588 8.1e-60
IGHPPKDA_00589 4.1e-11
IGHPPKDA_00590 3e-106 yoaK S Protein of unknown function (DUF1275)
IGHPPKDA_00591 1.9e-124 yjhF G Phosphoglycerate mutase family
IGHPPKDA_00592 1.9e-152 yitU 3.1.3.104 S hydrolase
IGHPPKDA_00593 2.6e-88 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IGHPPKDA_00594 1.7e-165 K LysR substrate binding domain
IGHPPKDA_00595 7.8e-227 EK Aminotransferase, class I
IGHPPKDA_00596 1.4e-180 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IGHPPKDA_00597 4.5e-118 ydfK S Protein of unknown function (DUF554)
IGHPPKDA_00598 2.3e-89
IGHPPKDA_00599 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IGHPPKDA_00600 7.8e-174 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
IGHPPKDA_00601 2.8e-129 rpl K Helix-turn-helix domain, rpiR family
IGHPPKDA_00602 1.6e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IGHPPKDA_00603 3.5e-25 chpR T PFAM SpoVT AbrB
IGHPPKDA_00605 3.3e-85
IGHPPKDA_00606 9.1e-225 dgoD 4.2.1.6 M Mandelate racemase muconate lactonizing enzyme
IGHPPKDA_00607 1.2e-244 G PTS system sugar-specific permease component
IGHPPKDA_00608 1.2e-45 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_00609 1.4e-78 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IGHPPKDA_00610 2.1e-106 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
IGHPPKDA_00611 0.0 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IGHPPKDA_00612 5.7e-44 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IGHPPKDA_00613 1.2e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_00614 2.3e-286 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IGHPPKDA_00615 3.9e-151 ypbG 2.7.1.2 GK ROK family
IGHPPKDA_00616 2.4e-104 S Metal-independent alpha-mannosidase (GH125)
IGHPPKDA_00617 1.8e-60 S Protein of unknown function (DUF806)
IGHPPKDA_00618 4.4e-53 S Phage tail assembly chaperone proteins, TAC
IGHPPKDA_00619 1.2e-52
IGHPPKDA_00620 3.1e-87 S peptidoglycan catabolic process
IGHPPKDA_00623 2.9e-16
IGHPPKDA_00624 2.2e-14 ytgB S Transglycosylase associated protein
IGHPPKDA_00626 3e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IGHPPKDA_00627 8.6e-181 D Alpha beta
IGHPPKDA_00628 2.4e-186 lipA I Carboxylesterase family
IGHPPKDA_00629 5.1e-207 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
IGHPPKDA_00630 1.1e-77 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGHPPKDA_00631 0.0 mtlR K Mga helix-turn-helix domain
IGHPPKDA_00632 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_00633 3.4e-129 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IGHPPKDA_00634 3.3e-149 S haloacid dehalogenase-like hydrolase
IGHPPKDA_00635 3.1e-43
IGHPPKDA_00636 1.3e-13
IGHPPKDA_00637 2.5e-184 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGHPPKDA_00638 1.1e-124 V ABC transporter
IGHPPKDA_00639 1.3e-205 bacI V MacB-like periplasmic core domain
IGHPPKDA_00640 0.0 M Leucine rich repeats (6 copies)
IGHPPKDA_00641 0.0 M Leucine rich repeats (6 copies)
IGHPPKDA_00642 3.9e-201 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
IGHPPKDA_00643 4.3e-225 amd 3.5.1.47 E Peptidase family M20/M25/M40
IGHPPKDA_00644 1.3e-79 S Threonine/Serine exporter, ThrE
IGHPPKDA_00645 4.5e-135 thrE S Putative threonine/serine exporter
IGHPPKDA_00646 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IGHPPKDA_00647 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IGHPPKDA_00649 8.2e-129 jag S R3H domain protein
IGHPPKDA_00650 7.6e-136 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IGHPPKDA_00651 2.1e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IGHPPKDA_00652 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IGHPPKDA_00653 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IGHPPKDA_00654 5.2e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IGHPPKDA_00655 1.7e-31 yaaA S S4 domain protein YaaA
IGHPPKDA_00656 6.2e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IGHPPKDA_00657 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IGHPPKDA_00658 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IGHPPKDA_00659 2.7e-126 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IGHPPKDA_00660 9.4e-74 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IGHPPKDA_00661 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
IGHPPKDA_00662 3.9e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IGHPPKDA_00663 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IGHPPKDA_00664 2.5e-38 S Phage portal protein
IGHPPKDA_00665 2.3e-27 S peptidoglycan catabolic process
IGHPPKDA_00666 2.5e-46 yfnA E Amino Acid
IGHPPKDA_00667 5.1e-75 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IGHPPKDA_00669 1.3e-85 mesE M Transport protein ComB
IGHPPKDA_00670 1.6e-24
IGHPPKDA_00672 4.3e-250 yjjP S Putative threonine/serine exporter
IGHPPKDA_00673 2.2e-30 spiA K TRANSCRIPTIONal
IGHPPKDA_00674 5.1e-44 S Enterocin A Immunity
IGHPPKDA_00675 5.4e-46 S Enterocin A Immunity
IGHPPKDA_00676 1.3e-137
IGHPPKDA_00677 2.3e-65
IGHPPKDA_00678 7.5e-55 K Transcriptional regulator PadR-like family
IGHPPKDA_00679 9.8e-104 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_00680 1.8e-206 MA20_36090 S Protein of unknown function (DUF2974)
IGHPPKDA_00681 5.2e-231 N Uncharacterized conserved protein (DUF2075)
IGHPPKDA_00682 6.2e-102
IGHPPKDA_00683 0.0 M domain protein
IGHPPKDA_00684 3.7e-238
IGHPPKDA_00685 9.3e-297 M Cna protein B-type domain
IGHPPKDA_00686 3.6e-146 3.4.22.70 M Sortase family
IGHPPKDA_00687 1.2e-230 ywhK S Membrane
IGHPPKDA_00688 3.1e-42
IGHPPKDA_00690 3.8e-148 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IGHPPKDA_00691 1.2e-201 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IGHPPKDA_00692 3.7e-224 pimH EGP Major facilitator Superfamily
IGHPPKDA_00693 1.3e-38
IGHPPKDA_00694 1.9e-32
IGHPPKDA_00695 7e-08
IGHPPKDA_00696 1e-09 yhjA K CsbD-like
IGHPPKDA_00697 5.4e-206 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IGHPPKDA_00698 7.2e-46
IGHPPKDA_00699 9.3e-206 ltrA S Bacterial low temperature requirement A protein (LtrA)
IGHPPKDA_00700 1.1e-121 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IGHPPKDA_00701 3.1e-93 ccpN K Domain in cystathionine beta-synthase and other proteins.
IGHPPKDA_00702 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
IGHPPKDA_00703 0.0 kup P Transport of potassium into the cell
IGHPPKDA_00704 6.7e-167 V ATPases associated with a variety of cellular activities
IGHPPKDA_00705 8.6e-218 S ABC-2 family transporter protein
IGHPPKDA_00706 2e-197
IGHPPKDA_00707 3.5e-260 pepC 3.4.22.40 E Peptidase C1-like family
IGHPPKDA_00708 4e-256 pepC 3.4.22.40 E aminopeptidase
IGHPPKDA_00709 8e-69 S Protein of unknown function (DUF805)
IGHPPKDA_00710 9.9e-51 HA62_12640 S GCN5-related N-acetyl-transferase
IGHPPKDA_00711 4.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
IGHPPKDA_00712 2.5e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IGHPPKDA_00713 3.3e-203 yacL S domain protein
IGHPPKDA_00714 4.4e-158 V ABC transporter, ATP-binding protein
IGHPPKDA_00715 1.4e-51 S ABC-2 family transporter protein
IGHPPKDA_00716 9.4e-43 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_00717 2e-49 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IGHPPKDA_00718 6.1e-85
IGHPPKDA_00719 2.7e-252 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGHPPKDA_00720 3.5e-290 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IGHPPKDA_00721 1.8e-133 K UTRA
IGHPPKDA_00722 8.2e-79 F Nucleoside 2-deoxyribosyltransferase
IGHPPKDA_00723 1.4e-251 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IGHPPKDA_00724 2.9e-63
IGHPPKDA_00725 8.9e-292 frvR K transcriptional antiterminator
IGHPPKDA_00726 8.7e-142 recX 2.4.1.337 GT4 S Regulatory protein RecX
IGHPPKDA_00727 6.4e-104 ygaC J Belongs to the UPF0374 family
IGHPPKDA_00728 1.2e-94
IGHPPKDA_00729 5.2e-72 S Acetyltransferase (GNAT) domain
IGHPPKDA_00730 2.7e-195 yueF S AI-2E family transporter
IGHPPKDA_00731 5.1e-243 hlyX S Transporter associated domain
IGHPPKDA_00732 6.5e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IGHPPKDA_00734 2.8e-45 XK27_09445 S Domain of unknown function (DUF1827)
IGHPPKDA_00735 0.0 clpE O Belongs to the ClpA ClpB family
IGHPPKDA_00736 2e-28
IGHPPKDA_00737 2.7e-39 ptsH G phosphocarrier protein HPR
IGHPPKDA_00738 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IGHPPKDA_00739 3.2e-256 iolT EGP Major facilitator Superfamily
IGHPPKDA_00740 4.7e-103 thiT S Thiamine transporter protein (Thia_YuaJ)
IGHPPKDA_00741 3.2e-78 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IGHPPKDA_00742 9.5e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IGHPPKDA_00743 5.8e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IGHPPKDA_00744 1.9e-40 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IGHPPKDA_00745 1.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IGHPPKDA_00746 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IGHPPKDA_00747 2.9e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IGHPPKDA_00748 4.5e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IGHPPKDA_00749 7.8e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IGHPPKDA_00750 1.1e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IGHPPKDA_00751 3.4e-233 purD 6.3.4.13 F Belongs to the GARS family
IGHPPKDA_00752 5.1e-75 copR K Copper transport repressor CopY TcrY
IGHPPKDA_00753 0.0 copB 3.6.3.4 P P-type ATPase
IGHPPKDA_00754 6.4e-110 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IGHPPKDA_00755 5.9e-205 T PhoQ Sensor
IGHPPKDA_00756 2.2e-122 K response regulator
IGHPPKDA_00757 9.7e-138 bceA V ABC transporter
IGHPPKDA_00758 0.0 V ABC transporter (permease)
IGHPPKDA_00759 4.8e-93 traP 1.14.99.57, 6.2.1.3 S heme oxygenase (decyclizing) activity
IGHPPKDA_00760 1.3e-134 yhfI S Metallo-beta-lactamase superfamily
IGHPPKDA_00761 3.2e-68 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IGHPPKDA_00762 5.1e-122 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IGHPPKDA_00763 0.0 glpQ 3.1.4.46 C phosphodiesterase
IGHPPKDA_00764 5.2e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
IGHPPKDA_00765 2.1e-22
IGHPPKDA_00766 1.2e-67
IGHPPKDA_00768 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IGHPPKDA_00769 5.3e-75 argR K Regulates arginine biosynthesis genes
IGHPPKDA_00770 4.7e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IGHPPKDA_00771 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IGHPPKDA_00772 3.9e-54 yheA S Control of competence regulator ComK, YlbF/YmcA
IGHPPKDA_00773 1.4e-181 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
IGHPPKDA_00774 8.1e-160 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IGHPPKDA_00775 2.7e-61 yhaH S YtxH-like protein
IGHPPKDA_00776 1e-75 hit FG histidine triad
IGHPPKDA_00777 3.1e-133 ecsA V ABC transporter, ATP-binding protein
IGHPPKDA_00778 1.2e-214 ecsB U ABC transporter
IGHPPKDA_00780 1e-147 ytmP 2.7.1.89 M Choline/ethanolamine kinase
IGHPPKDA_00781 1.8e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IGHPPKDA_00783 1.5e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IGHPPKDA_00784 5.6e-115 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IGHPPKDA_00785 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IGHPPKDA_00786 2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IGHPPKDA_00787 4.2e-119 ybhL S Inhibitor of apoptosis-promoting Bax1
IGHPPKDA_00788 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IGHPPKDA_00789 7.9e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IGHPPKDA_00790 1.4e-99 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IGHPPKDA_00791 7.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IGHPPKDA_00792 8.7e-251 dnaB L replication initiation and membrane attachment
IGHPPKDA_00793 3.6e-171 dnaI L Primosomal protein DnaI
IGHPPKDA_00794 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IGHPPKDA_00795 2e-103 yrgI 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
IGHPPKDA_00796 1.6e-53
IGHPPKDA_00797 2.8e-128 S SseB protein N-terminal domain
IGHPPKDA_00798 1.5e-77 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IGHPPKDA_00799 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IGHPPKDA_00800 5.6e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IGHPPKDA_00801 1.2e-97 yvdD 3.2.2.10 S Belongs to the LOG family
IGHPPKDA_00802 2.6e-180 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
IGHPPKDA_00803 1.3e-122 mhqD S Dienelactone hydrolase family
IGHPPKDA_00804 1.2e-190 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IGHPPKDA_00805 4.1e-172 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IGHPPKDA_00806 8.4e-96 yqeG S HAD phosphatase, family IIIA
IGHPPKDA_00807 1.3e-204 yqeH S Ribosome biogenesis GTPase YqeH
IGHPPKDA_00808 3.8e-48 yhbY J RNA-binding protein
IGHPPKDA_00809 5.7e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IGHPPKDA_00810 5.6e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IGHPPKDA_00811 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IGHPPKDA_00812 7.1e-138 yccK Q ubiE/COQ5 methyltransferase family
IGHPPKDA_00813 4.1e-209 ylbM S Belongs to the UPF0348 family
IGHPPKDA_00814 4.5e-97 yceD S Uncharacterized ACR, COG1399
IGHPPKDA_00815 1.2e-38 yhcX S Psort location Cytoplasmic, score
IGHPPKDA_00816 3.7e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IGHPPKDA_00817 7.9e-123 K response regulator
IGHPPKDA_00818 8e-288 arlS 2.7.13.3 T Histidine kinase
IGHPPKDA_00819 1.9e-173 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IGHPPKDA_00820 4.2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IGHPPKDA_00821 5.1e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGHPPKDA_00822 7.3e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IGHPPKDA_00823 6.3e-66 yodB K Transcriptional regulator, HxlR family
IGHPPKDA_00824 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IGHPPKDA_00825 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IGHPPKDA_00826 1.6e-205 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IGHPPKDA_00827 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
IGHPPKDA_00828 6.9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IGHPPKDA_00829 3.2e-119 yvqF S Cell wall-active antibiotics response 4TMS YvqF
IGHPPKDA_00830 1.4e-179 vraS 2.7.13.3 T Histidine kinase
IGHPPKDA_00831 6.9e-116 vraR K helix_turn_helix, Lux Regulon
IGHPPKDA_00832 2.1e-54 yneR S Belongs to the HesB IscA family
IGHPPKDA_00833 0.0 S Bacterial membrane protein YfhO
IGHPPKDA_00834 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IGHPPKDA_00835 7.3e-121 gluP 3.4.21.105 S Peptidase, S54 family
IGHPPKDA_00836 2.4e-40 yqgQ S Bacterial protein of unknown function (DUF910)
IGHPPKDA_00837 1.8e-178 glk 2.7.1.2 G Glucokinase
IGHPPKDA_00838 2.6e-73 yqhL P Rhodanese-like protein
IGHPPKDA_00839 1.5e-25 WQ51_02665 S Protein of unknown function (DUF3042)
IGHPPKDA_00840 2.9e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IGHPPKDA_00841 1.4e-239 ynbB 4.4.1.1 P aluminum resistance
IGHPPKDA_00842 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
IGHPPKDA_00843 1e-60 glnR K Transcriptional regulator
IGHPPKDA_00844 5.4e-261 glnA 6.3.1.2 E glutamine synthetase
IGHPPKDA_00845 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IGHPPKDA_00847 1e-16
IGHPPKDA_00848 3.2e-11
IGHPPKDA_00849 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IGHPPKDA_00850 9.4e-56 ysxB J Cysteine protease Prp
IGHPPKDA_00851 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IGHPPKDA_00852 2.7e-202 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IGHPPKDA_00854 1.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IGHPPKDA_00855 2.2e-76 yqhY S Asp23 family, cell envelope-related function
IGHPPKDA_00856 4.7e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IGHPPKDA_00857 1.6e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IGHPPKDA_00858 7.7e-199 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IGHPPKDA_00859 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IGHPPKDA_00860 4.6e-149 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IGHPPKDA_00861 6.1e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IGHPPKDA_00862 5.8e-74 argR K Regulates arginine biosynthesis genes
IGHPPKDA_00863 0.0 recN L May be involved in recombinational repair of damaged DNA
IGHPPKDA_00865 1.8e-50
IGHPPKDA_00866 1.6e-91 rssA S Patatin-like phospholipase
IGHPPKDA_00867 1.9e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IGHPPKDA_00868 1.3e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IGHPPKDA_00869 1.6e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IGHPPKDA_00870 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IGHPPKDA_00871 2.2e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IGHPPKDA_00872 8.9e-256 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IGHPPKDA_00873 5.1e-136 stp 3.1.3.16 T phosphatase
IGHPPKDA_00874 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IGHPPKDA_00875 7.6e-174 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IGHPPKDA_00876 3.6e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IGHPPKDA_00877 2.1e-128 thiN 2.7.6.2 H thiamine pyrophosphokinase
IGHPPKDA_00878 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IGHPPKDA_00879 2.3e-57 asp S Asp23 family, cell envelope-related function
IGHPPKDA_00880 9.3e-311 yloV S DAK2 domain fusion protein YloV
IGHPPKDA_00881 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IGHPPKDA_00882 2.3e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IGHPPKDA_00883 3e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IGHPPKDA_00884 5.7e-194 oppD P Belongs to the ABC transporter superfamily
IGHPPKDA_00885 1.4e-178 oppF P Belongs to the ABC transporter superfamily
IGHPPKDA_00886 9.2e-170 oppB P ABC transporter permease
IGHPPKDA_00887 1.8e-138 oppC EP Binding-protein-dependent transport system inner membrane component
IGHPPKDA_00888 0.0 oppA1 E ABC transporter substrate-binding protein
IGHPPKDA_00889 1.7e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IGHPPKDA_00890 0.0 smc D Required for chromosome condensation and partitioning
IGHPPKDA_00891 1.4e-181 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IGHPPKDA_00892 8.8e-53
IGHPPKDA_00894 3.8e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IGHPPKDA_00895 1.8e-230 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IGHPPKDA_00896 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IGHPPKDA_00897 2.2e-38 ylqC S Belongs to the UPF0109 family
IGHPPKDA_00898 2.2e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IGHPPKDA_00899 1.1e-144 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IGHPPKDA_00900 2.9e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IGHPPKDA_00901 2.1e-19
IGHPPKDA_00902 4e-37 ynzC S UPF0291 protein
IGHPPKDA_00903 4.8e-29 yneF S UPF0154 protein
IGHPPKDA_00904 0.0 mdlA V ABC transporter
IGHPPKDA_00905 0.0 mdlB V ABC transporter
IGHPPKDA_00906 6.7e-142 yejC S Protein of unknown function (DUF1003)
IGHPPKDA_00907 5.9e-218 yfnA E Amino Acid
IGHPPKDA_00908 2.6e-123 plsC 2.3.1.51 I Acyltransferase
IGHPPKDA_00909 3.2e-130 yabB 2.1.1.223 L Methyltransferase small domain
IGHPPKDA_00910 5.2e-46 yazA L GIY-YIG catalytic domain protein
IGHPPKDA_00911 1e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
IGHPPKDA_00912 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IGHPPKDA_00913 5.9e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IGHPPKDA_00914 1.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IGHPPKDA_00915 2.7e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IGHPPKDA_00916 4.5e-138 cdsA 2.7.7.41 S Belongs to the CDS family
IGHPPKDA_00917 5.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IGHPPKDA_00918 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IGHPPKDA_00919 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IGHPPKDA_00920 1.7e-84 rimP J Required for maturation of 30S ribosomal subunits
IGHPPKDA_00921 1.1e-194 nusA K Participates in both transcription termination and antitermination
IGHPPKDA_00922 1.7e-45 ylxR K Protein of unknown function (DUF448)
IGHPPKDA_00923 6.5e-45 ylxQ J ribosomal protein
IGHPPKDA_00924 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IGHPPKDA_00925 4.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IGHPPKDA_00926 1e-142 terC P Integral membrane protein TerC family
IGHPPKDA_00927 2e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IGHPPKDA_00928 6.9e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IGHPPKDA_00929 4.1e-225 hemN H Involved in the biosynthesis of porphyrin-containing compound
IGHPPKDA_00930 1.4e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IGHPPKDA_00931 3.4e-98 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IGHPPKDA_00932 4.4e-309 dnaK O Heat shock 70 kDa protein
IGHPPKDA_00933 1.9e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IGHPPKDA_00934 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IGHPPKDA_00935 1.8e-23
IGHPPKDA_00936 2.5e-83 6.3.3.2 S ASCH
IGHPPKDA_00937 1.8e-57
IGHPPKDA_00938 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IGHPPKDA_00939 5.3e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IGHPPKDA_00940 4.5e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IGHPPKDA_00941 1.8e-53 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
IGHPPKDA_00942 1.4e-155 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
IGHPPKDA_00943 2.9e-99 K Bacterial regulatory proteins, tetR family
IGHPPKDA_00944 2.2e-15 1.6.5.2 S Flavodoxin-like fold
IGHPPKDA_00945 9e-80 1.6.5.2 S Flavodoxin-like fold
IGHPPKDA_00946 3.6e-149 comGB NU type II secretion system
IGHPPKDA_00947 7e-153 comGA NU Type II IV secretion system protein
IGHPPKDA_00948 7.6e-132 yebC K Transcriptional regulatory protein
IGHPPKDA_00949 1.5e-78 S VanZ like family
IGHPPKDA_00950 0.0 pepF2 E Oligopeptidase F
IGHPPKDA_00952 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IGHPPKDA_00953 2.4e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IGHPPKDA_00954 6.5e-164 ybbR S YbbR-like protein
IGHPPKDA_00955 2.2e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IGHPPKDA_00956 9.3e-130 V AAA domain, putative AbiEii toxin, Type IV TA system
IGHPPKDA_00957 1.6e-181 V ABC transporter
IGHPPKDA_00958 1.1e-110 K Transcriptional regulator
IGHPPKDA_00959 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
IGHPPKDA_00961 8e-207 potD P ABC transporter
IGHPPKDA_00962 4.1e-142 potC P ABC transporter permease
IGHPPKDA_00963 5.5e-147 potB P ABC transporter permease
IGHPPKDA_00964 4e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IGHPPKDA_00965 2.9e-96 puuR K Cupin domain
IGHPPKDA_00966 0.0 yjcE P Sodium proton antiporter
IGHPPKDA_00967 1.5e-166 murB 1.3.1.98 M Cell wall formation
IGHPPKDA_00968 7.5e-151 xth 3.1.11.2 L exodeoxyribonuclease III
IGHPPKDA_00969 2.4e-98 dnaQ 2.7.7.7 L DNA polymerase III
IGHPPKDA_00970 8e-214 ysdA CP ABC-2 family transporter protein
IGHPPKDA_00971 2.4e-164 natA S ABC transporter, ATP-binding protein
IGHPPKDA_00973 1.3e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IGHPPKDA_00974 1.8e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IGHPPKDA_00975 6.6e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IGHPPKDA_00976 3.1e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
IGHPPKDA_00977 9e-92 yxjI
IGHPPKDA_00978 3.7e-105 3.2.2.20 K Acetyltransferase (GNAT) domain
IGHPPKDA_00979 3.5e-194 malK P ATPases associated with a variety of cellular activities
IGHPPKDA_00980 5.7e-166 malG P ABC-type sugar transport systems, permease components
IGHPPKDA_00981 1.9e-147 malF G Binding-protein-dependent transport system inner membrane component
IGHPPKDA_00982 3e-232 malE G Bacterial extracellular solute-binding protein
IGHPPKDA_00983 9.2e-239 YSH1 S Metallo-beta-lactamase superfamily
IGHPPKDA_00984 2.5e-23 ydcG K Helix-turn-helix XRE-family like proteins
IGHPPKDA_00985 5.2e-18
IGHPPKDA_00986 5.2e-15 msmX P Belongs to the ABC transporter superfamily
IGHPPKDA_00987 5.7e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
IGHPPKDA_00988 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IGHPPKDA_00989 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
IGHPPKDA_00990 1e-75 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
IGHPPKDA_00991 2.7e-155 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
IGHPPKDA_00992 2.5e-77 yhfI S Metallo-beta-lactamase superfamily
IGHPPKDA_00993 4.4e-222 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IGHPPKDA_00994 4e-137 P Belongs to the nlpA lipoprotein family
IGHPPKDA_00995 5.9e-149 P Belongs to the nlpA lipoprotein family
IGHPPKDA_00996 6.1e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IGHPPKDA_00997 3.7e-104 metI P ABC transporter permease
IGHPPKDA_00998 2.9e-142 sufC O FeS assembly ATPase SufC
IGHPPKDA_00999 5e-190 sufD O FeS assembly protein SufD
IGHPPKDA_01000 1.4e-220 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IGHPPKDA_01001 1e-78 nifU C SUF system FeS assembly protein, NifU family
IGHPPKDA_01002 1.1e-280 sufB O assembly protein SufB
IGHPPKDA_01003 2.7e-22
IGHPPKDA_01004 2.4e-65 yueI S Protein of unknown function (DUF1694)
IGHPPKDA_01005 1.5e-180 S Protein of unknown function (DUF2785)
IGHPPKDA_01006 3e-116 yhfA S HAD hydrolase, family IA, variant 3
IGHPPKDA_01007 2.1e-152 2.3.1.19 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_01008 2.9e-82 usp6 T universal stress protein
IGHPPKDA_01009 1.1e-38
IGHPPKDA_01011 8.7e-240 rarA L recombination factor protein RarA
IGHPPKDA_01012 0.0 gshF 6.3.2.2, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
IGHPPKDA_01013 7.1e-77 yueI S Protein of unknown function (DUF1694)
IGHPPKDA_01014 4.3e-109 yktB S Belongs to the UPF0637 family
IGHPPKDA_01015 1.7e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IGHPPKDA_01016 2.8e-149 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IGHPPKDA_01017 4.3e-121 G alpha-ribazole phosphatase activity
IGHPPKDA_01018 2e-152 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IGHPPKDA_01019 1.4e-170 IQ NAD dependent epimerase/dehydratase family
IGHPPKDA_01020 1.6e-137 pnuC H nicotinamide mononucleotide transporter
IGHPPKDA_01021 1.4e-133 dck 2.7.1.74 F deoxynucleoside kinase
IGHPPKDA_01022 9.8e-157 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
IGHPPKDA_01023 0.0 oppA E ABC transporter, substratebinding protein
IGHPPKDA_01024 8.3e-157 T GHKL domain
IGHPPKDA_01025 4.7e-120 T Transcriptional regulatory protein, C terminal
IGHPPKDA_01026 1.7e-168 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
IGHPPKDA_01027 5.2e-44 S ABC-2 family transporter protein
IGHPPKDA_01028 6.7e-40 S ABC-2 family transporter protein
IGHPPKDA_01029 1.1e-158 K Transcriptional regulator
IGHPPKDA_01030 3.6e-78 yphH S Cupin domain
IGHPPKDA_01031 2.7e-54 yphJ 4.1.1.44 S decarboxylase
IGHPPKDA_01032 2.3e-113 GM NAD(P)H-binding
IGHPPKDA_01033 1e-38 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
IGHPPKDA_01034 4e-121 gst 2.5.1.18 O Glutathione S-transferase, C-terminal domain
IGHPPKDA_01035 2.4e-110 K Psort location Cytoplasmic, score
IGHPPKDA_01036 1e-151 2.3.1.128 K Acetyltransferase (GNAT) domain
IGHPPKDA_01037 3.7e-87 K Acetyltransferase (GNAT) domain
IGHPPKDA_01038 7.5e-132 T Histidine kinase
IGHPPKDA_01039 2.6e-87 K helix_turn_helix, arabinose operon control protein
IGHPPKDA_01040 3.4e-149 P Bacterial extracellular solute-binding protein
IGHPPKDA_01041 1.7e-156 fbpC 3.6.3.30, 3.6.3.31 P TOBE domain
IGHPPKDA_01042 2e-249 sfuB P Binding-protein-dependent transport system inner membrane component
IGHPPKDA_01043 4.6e-07 sfuB P thiamine transport
IGHPPKDA_01044 3.5e-73 L Transposase
IGHPPKDA_01045 2.7e-57 S endonuclease exonuclease phosphatase family protein
IGHPPKDA_01046 1.6e-31
IGHPPKDA_01047 2.1e-39 L RePlication protein
IGHPPKDA_01050 3.4e-33 S Phospholipase A2
IGHPPKDA_01051 2.7e-66 M Glycosyl hydrolases family 25
IGHPPKDA_01052 7.3e-59 licD4 M O-Antigen ligase
IGHPPKDA_01053 7.5e-80 lsgC M Glycosyl transferases group 1
IGHPPKDA_01054 3.5e-150 cps2I S Psort location CytoplasmicMembrane, score
IGHPPKDA_01055 3.8e-99 M group 2 family protein
IGHPPKDA_01056 2.1e-122 eps4I GM Male sterility protein
IGHPPKDA_01057 9.3e-103 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
IGHPPKDA_01058 6.9e-116 licD3 M LicD family
IGHPPKDA_01059 2.7e-85 lsgF M Glycosyl transferase family 2
IGHPPKDA_01060 1.2e-197 wcaJ M Bacterial sugar transferase
IGHPPKDA_01062 8.2e-75 S ErfK ybiS ycfS ynhG family protein
IGHPPKDA_01063 3.1e-55
IGHPPKDA_01064 5.7e-56 XK27_02965 I Acyltransferase family
IGHPPKDA_01065 1.6e-102 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IGHPPKDA_01066 1.3e-99 V Beta-lactamase
IGHPPKDA_01067 6.3e-147 cps2D 5.1.3.2 M RmlD substrate binding domain
IGHPPKDA_01068 7.4e-110 glnP P ABC transporter permease
IGHPPKDA_01069 4.6e-109 gluC P ABC transporter permease
IGHPPKDA_01070 3.8e-148 glnH ET ABC transporter substrate-binding protein
IGHPPKDA_01071 7.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IGHPPKDA_01072 4.7e-177
IGHPPKDA_01074 6.1e-84 zur P Belongs to the Fur family
IGHPPKDA_01075 2.2e-09
IGHPPKDA_01076 1e-110 gmk2 2.7.4.8 F Guanylate kinase
IGHPPKDA_01077 9.6e-68 GnaT 2.5.1.16 K Acetyltransferase (GNAT) domain
IGHPPKDA_01078 2.5e-124 spl M NlpC/P60 family
IGHPPKDA_01079 4.4e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IGHPPKDA_01080 5.9e-58 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IGHPPKDA_01081 2.5e-98 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IGHPPKDA_01082 1e-54 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
IGHPPKDA_01083 3.1e-40 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IGHPPKDA_01084 1.4e-104 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IGHPPKDA_01085 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
IGHPPKDA_01086 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IGHPPKDA_01087 8.9e-286 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
IGHPPKDA_01088 4.7e-200 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
IGHPPKDA_01089 2.3e-196 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IGHPPKDA_01090 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IGHPPKDA_01091 1.2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
IGHPPKDA_01095 2.1e-85 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IGHPPKDA_01096 1.4e-50 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_01097 1.6e-266 gatC G PTS system sugar-specific permease component
IGHPPKDA_01098 5.6e-26
IGHPPKDA_01099 1e-122 S Domain of unknown function (DUF4867)
IGHPPKDA_01100 4.9e-176 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
IGHPPKDA_01101 2.5e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
IGHPPKDA_01102 2.9e-93 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
IGHPPKDA_01103 2.7e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
IGHPPKDA_01104 4.2e-141 lacR K DeoR C terminal sensor domain
IGHPPKDA_01105 3.8e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IGHPPKDA_01106 6.9e-209 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IGHPPKDA_01107 0.0 sbcC L Putative exonuclease SbcCD, C subunit
IGHPPKDA_01108 2.1e-14
IGHPPKDA_01109 2.2e-76 hsp1 O Belongs to the small heat shock protein (HSP20) family
IGHPPKDA_01111 1.2e-210 mutY L A G-specific adenine glycosylase
IGHPPKDA_01112 3.6e-148 cytC6 I alpha/beta hydrolase fold
IGHPPKDA_01113 2.1e-120 yrkL S Flavodoxin-like fold
IGHPPKDA_01115 1.5e-86 S Short repeat of unknown function (DUF308)
IGHPPKDA_01116 2.7e-117 S Psort location Cytoplasmic, score
IGHPPKDA_01117 1.6e-154 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IGHPPKDA_01118 2.8e-196
IGHPPKDA_01119 3.9e-07
IGHPPKDA_01120 1.5e-115 ywnB S NAD(P)H-binding
IGHPPKDA_01121 0.0 bglB 3.2.1.21 GH3 G hydrolase, family 3
IGHPPKDA_01122 1e-165 XK27_00670 S ABC transporter substrate binding protein
IGHPPKDA_01123 3.1e-165 XK27_00670 S ABC transporter
IGHPPKDA_01124 1.9e-154 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
IGHPPKDA_01125 8.8e-142 cmpC S ABC transporter, ATP-binding protein
IGHPPKDA_01126 8e-174 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
IGHPPKDA_01127 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
IGHPPKDA_01128 6.2e-182 ykcC GT2 M Glycosyl transferase family 2
IGHPPKDA_01129 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
IGHPPKDA_01130 4.1e-71 S GtrA-like protein
IGHPPKDA_01131 9.6e-43 L Transposase
IGHPPKDA_01132 3.3e-43 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
IGHPPKDA_01133 9.8e-59 M Peptidoglycan-binding domain 1 protein
IGHPPKDA_01134 4.3e-204 S Uncharacterized protein conserved in bacteria (DUF2325)
IGHPPKDA_01135 1.6e-41 4.4.1.8 E Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IGHPPKDA_01136 1.8e-164 4.4.1.8 E Aminotransferase, class I
IGHPPKDA_01137 8.7e-193 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IGHPPKDA_01138 4.3e-250 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGHPPKDA_01139 8.8e-59 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_01140 2.8e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IGHPPKDA_01141 1.2e-188 ypdE E M42 glutamyl aminopeptidase
IGHPPKDA_01142 0.0 licR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IGHPPKDA_01143 8.1e-243 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IGHPPKDA_01144 7e-295 E ABC transporter, substratebinding protein
IGHPPKDA_01145 3.5e-109 S Acetyltransferase (GNAT) family
IGHPPKDA_01146 6.3e-94 S ABC-type cobalt transport system, permease component
IGHPPKDA_01147 8.1e-241 P ABC transporter
IGHPPKDA_01148 4.7e-109 P cobalt transport
IGHPPKDA_01149 3.7e-128 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IGHPPKDA_01150 2.2e-82 thiW S Thiamine-precursor transporter protein (ThiW)
IGHPPKDA_01151 2.3e-148 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IGHPPKDA_01152 5.6e-107 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IGHPPKDA_01153 2.1e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IGHPPKDA_01154 1.2e-97 E Amino acid permease
IGHPPKDA_01155 5.2e-133 E Amino acid permease
IGHPPKDA_01156 5.3e-29
IGHPPKDA_01157 1.5e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
IGHPPKDA_01158 8.6e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IGHPPKDA_01159 4.5e-283 rbsA 3.6.3.17 G ABC transporter
IGHPPKDA_01160 3.6e-145 rbsC U Belongs to the binding-protein-dependent transport system permease family
IGHPPKDA_01161 3.6e-166 rbsB G Periplasmic binding protein domain
IGHPPKDA_01162 3.1e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGHPPKDA_01163 1.8e-35 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IGHPPKDA_01164 0.0 pbpC M NTF2-like N-terminal transpeptidase domain
IGHPPKDA_01165 1.3e-238 ydiC1 EGP Major facilitator Superfamily
IGHPPKDA_01166 4.7e-73 K helix_turn_helix multiple antibiotic resistance protein
IGHPPKDA_01167 3.6e-102
IGHPPKDA_01168 2.6e-24
IGHPPKDA_01169 3.2e-63
IGHPPKDA_01170 7.5e-35
IGHPPKDA_01172 5.2e-268 frdC 1.3.5.4 C HI0933-like protein
IGHPPKDA_01173 1.5e-36 S sequence-specific DNA binding
IGHPPKDA_01174 3e-60 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IGHPPKDA_01175 5.6e-41
IGHPPKDA_01176 0.0 M domain protein
IGHPPKDA_01177 1.2e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IGHPPKDA_01178 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IGHPPKDA_01179 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IGHPPKDA_01180 1.2e-199 yfjR K WYL domain
IGHPPKDA_01181 6.5e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
IGHPPKDA_01182 1.6e-68 psiE S Phosphate-starvation-inducible E
IGHPPKDA_01183 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IGHPPKDA_01184 4e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IGHPPKDA_01185 1.7e-108 rplD J Forms part of the polypeptide exit tunnel
IGHPPKDA_01186 2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IGHPPKDA_01187 2.9e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IGHPPKDA_01188 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IGHPPKDA_01189 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IGHPPKDA_01190 6.2e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IGHPPKDA_01191 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IGHPPKDA_01192 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
IGHPPKDA_01193 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IGHPPKDA_01194 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IGHPPKDA_01195 1.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IGHPPKDA_01196 8.5e-96 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IGHPPKDA_01197 7e-26 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IGHPPKDA_01198 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IGHPPKDA_01199 1.7e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IGHPPKDA_01200 1.8e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IGHPPKDA_01201 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IGHPPKDA_01202 3.9e-24 rpmD J Ribosomal protein L30
IGHPPKDA_01203 6.5e-62 rplO J Binds to the 23S rRNA
IGHPPKDA_01204 2e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IGHPPKDA_01205 1.6e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IGHPPKDA_01206 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IGHPPKDA_01207 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IGHPPKDA_01208 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IGHPPKDA_01209 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IGHPPKDA_01210 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGHPPKDA_01211 4.8e-61 rplQ J Ribosomal protein L17
IGHPPKDA_01212 1.6e-100
IGHPPKDA_01213 1e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IGHPPKDA_01214 6e-157 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IGHPPKDA_01215 8.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IGHPPKDA_01216 2.9e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IGHPPKDA_01217 1.3e-110 tipA K TipAS antibiotic-recognition domain
IGHPPKDA_01218 1.1e-33
IGHPPKDA_01219 9.3e-127 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
IGHPPKDA_01220 3.6e-183 yxeA V FtsX-like permease family
IGHPPKDA_01221 1.9e-107 K Bacterial regulatory proteins, tetR family
IGHPPKDA_01222 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IGHPPKDA_01223 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IGHPPKDA_01224 4.6e-50 S Phage head-tail joining protein
IGHPPKDA_01225 3.6e-274 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IGHPPKDA_01226 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IGHPPKDA_01227 3.2e-45 maf D nucleoside-triphosphate diphosphatase activity
IGHPPKDA_01228 2.1e-38 maf D nucleoside-triphosphate diphosphatase activity
IGHPPKDA_01229 1.6e-61 S Domain of unknown function (DUF4811)
IGHPPKDA_01230 1.6e-258 lmrB EGP Major facilitator Superfamily
IGHPPKDA_01231 9e-259 yhdP S Transporter associated domain
IGHPPKDA_01232 1.8e-133 S Uncharacterized protein conserved in bacteria (DUF2263)
IGHPPKDA_01233 1.5e-117 yfeJ 6.3.5.2 F glutamine amidotransferase
IGHPPKDA_01234 6.1e-95 T Sh3 type 3 domain protein
IGHPPKDA_01235 6.9e-101 Q methyltransferase
IGHPPKDA_01237 2.2e-114 GM NmrA-like family
IGHPPKDA_01238 9.5e-197 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IGHPPKDA_01239 1.7e-79 C Flavodoxin
IGHPPKDA_01240 3.5e-70 adhR K helix_turn_helix, mercury resistance
IGHPPKDA_01241 7.1e-87 bioY S BioY family
IGHPPKDA_01242 1.7e-63
IGHPPKDA_01243 4.1e-225 queG 1.17.99.6 C Domain of unknown function (DUF1730)
IGHPPKDA_01244 6.4e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
IGHPPKDA_01245 1.8e-55 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_01246 5e-78 usp5 T universal stress protein
IGHPPKDA_01247 1.5e-112 tag 3.2.2.20 L glycosylase
IGHPPKDA_01248 2.6e-166 yicL EG EamA-like transporter family
IGHPPKDA_01249 2.3e-23
IGHPPKDA_01250 1.4e-86
IGHPPKDA_01251 8.6e-40
IGHPPKDA_01252 1.4e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IGHPPKDA_01253 3.1e-237 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
IGHPPKDA_01254 2.3e-278 cydA 1.10.3.14 C ubiquinol oxidase
IGHPPKDA_01255 1.3e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IGHPPKDA_01256 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IGHPPKDA_01257 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IGHPPKDA_01258 1.8e-48 yvlA
IGHPPKDA_01259 3.8e-63 S Protein of unknown function (DUF1093)
IGHPPKDA_01260 4.6e-219 ywhK S Membrane
IGHPPKDA_01261 4.8e-140
IGHPPKDA_01262 4.1e-181 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IGHPPKDA_01263 1.2e-121 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IGHPPKDA_01265 1e-13 S L1 transposable element dsRBD-like domain
IGHPPKDA_01266 8.2e-48 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IGHPPKDA_01267 3.9e-124 oppD EP AAA domain, putative AbiEii toxin, Type IV TA system
IGHPPKDA_01269 1.3e-07
IGHPPKDA_01270 9.3e-200 S peptidoglycan catabolic process
IGHPPKDA_01273 7e-57
IGHPPKDA_01275 2.1e-32
IGHPPKDA_01276 1.3e-191 S cellulase activity
IGHPPKDA_01277 7.9e-144 S Phage tail protein
IGHPPKDA_01278 5.4e-272 S phage tail tape measure protein
IGHPPKDA_01279 8.1e-55
IGHPPKDA_01280 8.1e-49 S Phage tail assembly chaperone protein, TAC
IGHPPKDA_01281 1.2e-98 S Phage tail tube protein
IGHPPKDA_01282 4.3e-68 S Protein of unknown function (DUF3168)
IGHPPKDA_01283 1.1e-57 S Bacteriophage HK97-gp10, putative tail-component
IGHPPKDA_01284 1.1e-49
IGHPPKDA_01285 2.3e-60 S Phage gp6-like head-tail connector protein
IGHPPKDA_01286 1e-151
IGHPPKDA_01287 1.8e-182 S Phage major capsid protein E
IGHPPKDA_01288 1.2e-46
IGHPPKDA_01289 2.8e-82 S Domain of unknown function (DUF4355)
IGHPPKDA_01291 1.2e-177 S head morphogenesis protein, SPP1 gp7 family
IGHPPKDA_01292 1.8e-256 S Phage portal protein
IGHPPKDA_01293 6.4e-248 S Terminase-like family
IGHPPKDA_01294 2.5e-16 L DNA packaging
IGHPPKDA_01297 8.9e-220 S GcrA cell cycle regulator
IGHPPKDA_01299 3e-38 gepA K Protein of unknown function (DUF4065)
IGHPPKDA_01300 2.8e-70
IGHPPKDA_01304 2.6e-83 S YopX protein
IGHPPKDA_01306 1.1e-36
IGHPPKDA_01307 6.2e-35
IGHPPKDA_01309 4.3e-65 S Protein of unknown function (DUF1642)
IGHPPKDA_01310 3e-07
IGHPPKDA_01312 1.3e-12
IGHPPKDA_01313 1.8e-55 S Protein of unknown function (DUF1064)
IGHPPKDA_01314 1.2e-50
IGHPPKDA_01315 3.3e-07 K Cro/C1-type HTH DNA-binding domain
IGHPPKDA_01317 6.4e-131 nodB3 G Polysaccharide deacetylase
IGHPPKDA_01318 4.8e-238 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IGHPPKDA_01319 5.3e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
IGHPPKDA_01320 0.0 E amino acid
IGHPPKDA_01321 2.4e-133 cysA V ABC transporter, ATP-binding protein
IGHPPKDA_01322 0.0 V FtsX-like permease family
IGHPPKDA_01323 3.5e-128 pgm3 G Phosphoglycerate mutase family
IGHPPKDA_01324 2.2e-187 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IGHPPKDA_01325 2.8e-241 mntH P H( )-stimulated, divalent metal cation uptake system
IGHPPKDA_01326 1.3e-81 yjhE S Phage tail protein
IGHPPKDA_01327 1.1e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IGHPPKDA_01328 0.0 yjbQ P TrkA C-terminal domain protein
IGHPPKDA_01329 1.4e-21
IGHPPKDA_01330 0.0 helD 3.6.4.12 L DNA helicase
IGHPPKDA_01331 8.5e-84 ykhA 3.1.2.20 I Thioesterase superfamily
IGHPPKDA_01332 3.7e-276 pipD E Dipeptidase
IGHPPKDA_01333 3e-23
IGHPPKDA_01334 1.3e-12
IGHPPKDA_01335 1.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
IGHPPKDA_01336 4.6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IGHPPKDA_01337 3.6e-176 L Belongs to the 'phage' integrase family
IGHPPKDA_01339 1.5e-20
IGHPPKDA_01340 1.2e-50 S Domain of unknown function (DUF4352)
IGHPPKDA_01341 3.5e-73 E Zn peptidase
IGHPPKDA_01342 4.5e-55 3.4.21.88 K Helix-turn-helix domain
IGHPPKDA_01343 4.6e-33 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_01347 4.4e-14
IGHPPKDA_01349 1.6e-13
IGHPPKDA_01352 2.1e-149 recT L RecT family
IGHPPKDA_01353 2.6e-149 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
IGHPPKDA_01354 1.6e-129 L Replication initiation and membrane attachment
IGHPPKDA_01355 3.7e-66 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IGHPPKDA_01357 1.6e-32
IGHPPKDA_01358 1.4e-53 trxC O Belongs to the thioredoxin family
IGHPPKDA_01359 6.3e-137 thrE S Putative threonine/serine exporter
IGHPPKDA_01360 1.4e-75 S Threonine/Serine exporter, ThrE
IGHPPKDA_01362 3.2e-209 livJ E Receptor family ligand binding region
IGHPPKDA_01363 4.3e-150 livH U Branched-chain amino acid transport system / permease component
IGHPPKDA_01364 2.7e-121 livM E Branched-chain amino acid transport system / permease component
IGHPPKDA_01365 2.8e-140 livG E Branched-chain amino acid ATP-binding cassette transporter
IGHPPKDA_01366 1.5e-124 livF E ABC transporter
IGHPPKDA_01367 3.1e-167 S Alpha/beta hydrolase of unknown function (DUF915)
IGHPPKDA_01368 4.2e-234 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGHPPKDA_01369 7.6e-118 XK27_12570 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IGHPPKDA_01370 2.8e-117 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IGHPPKDA_01371 2.6e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IGHPPKDA_01372 3.4e-129 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IGHPPKDA_01373 6.1e-152 M NlpC P60 family protein
IGHPPKDA_01377 1.2e-260 nox 1.6.3.4 C NADH oxidase
IGHPPKDA_01378 3.5e-141 sepS16B
IGHPPKDA_01379 3.4e-118
IGHPPKDA_01380 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
IGHPPKDA_01381 2.5e-239 G Bacterial extracellular solute-binding protein
IGHPPKDA_01382 5.8e-86
IGHPPKDA_01383 0.0 strH 3.2.1.52 GH20 G Gram-positive signal peptide protein, YSIRK family
IGHPPKDA_01384 3.3e-194 manA 5.3.1.8 G mannose-6-phosphate isomerase
IGHPPKDA_01385 1.2e-129 XK27_08435 K UTRA
IGHPPKDA_01386 4.5e-219 agaS G SIS domain
IGHPPKDA_01387 9.9e-227 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IGHPPKDA_01388 0.0 bgaC 3.2.1.23 G Glycosyl hydrolases family 35
IGHPPKDA_01389 8.3e-67 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
IGHPPKDA_01390 1.3e-176 yvdE K helix_turn _helix lactose operon repressor
IGHPPKDA_01391 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IGHPPKDA_01392 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IGHPPKDA_01393 9.9e-140 est 3.1.1.1 S Serine aminopeptidase, S33
IGHPPKDA_01394 2.4e-31 secG U Preprotein translocase
IGHPPKDA_01395 4.8e-293 clcA P chloride
IGHPPKDA_01396 2.5e-56
IGHPPKDA_01397 7.9e-230 mdt(A) EGP Major facilitator Superfamily
IGHPPKDA_01398 1.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IGHPPKDA_01399 7.8e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IGHPPKDA_01400 4.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IGHPPKDA_01401 2.8e-193 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IGHPPKDA_01402 4e-187 cggR K Putative sugar-binding domain
IGHPPKDA_01403 1.3e-08 M Host cell surface-exposed lipoprotein
IGHPPKDA_01405 1.9e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IGHPPKDA_01406 7.1e-80 ohrR K helix_turn_helix multiple antibiotic resistance protein
IGHPPKDA_01407 3.1e-170 whiA K May be required for sporulation
IGHPPKDA_01408 2.4e-192 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IGHPPKDA_01409 9.7e-166 rapZ S Displays ATPase and GTPase activities
IGHPPKDA_01410 1.8e-85 S Short repeat of unknown function (DUF308)
IGHPPKDA_01411 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IGHPPKDA_01412 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IGHPPKDA_01413 6.5e-119 yfbR S HD containing hydrolase-like enzyme
IGHPPKDA_01415 0.0 V FtsX-like permease family
IGHPPKDA_01416 4.5e-91 V ABC transporter
IGHPPKDA_01417 3.4e-167 T His Kinase A (phosphoacceptor) domain
IGHPPKDA_01418 6.3e-114 T Transcriptional regulatory protein, C terminal
IGHPPKDA_01419 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IGHPPKDA_01420 2.4e-178 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IGHPPKDA_01421 6.9e-195 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IGHPPKDA_01422 9.5e-166 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IGHPPKDA_01423 2.1e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IGHPPKDA_01424 4.4e-34 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IGHPPKDA_01425 1.4e-30
IGHPPKDA_01426 2.4e-262 yvlB S Putative adhesin
IGHPPKDA_01427 1e-119 phoU P Plays a role in the regulation of phosphate uptake
IGHPPKDA_01428 9.3e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IGHPPKDA_01429 1.2e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IGHPPKDA_01430 4.8e-157 pstA P Phosphate transport system permease protein PstA
IGHPPKDA_01431 3.6e-155 pstC P probably responsible for the translocation of the substrate across the membrane
IGHPPKDA_01432 1.2e-152 pstS P Phosphate
IGHPPKDA_01433 2.1e-307 phoR 2.7.13.3 T Histidine kinase
IGHPPKDA_01434 2.4e-130 K response regulator
IGHPPKDA_01435 1e-201 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
IGHPPKDA_01437 5.4e-124 ftsE D ABC transporter
IGHPPKDA_01438 3.9e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IGHPPKDA_01439 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IGHPPKDA_01440 2.1e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IGHPPKDA_01441 1.9e-81 comFC S Competence protein
IGHPPKDA_01442 4.4e-236 comFA L Helicase C-terminal domain protein
IGHPPKDA_01443 5.2e-116 yvyE 3.4.13.9 S YigZ family
IGHPPKDA_01444 3.1e-231 rny S Endoribonuclease that initiates mRNA decay
IGHPPKDA_01445 8e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IGHPPKDA_01446 7.8e-230 cinA 3.5.1.42 S Belongs to the CinA family
IGHPPKDA_01447 5.4e-104 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IGHPPKDA_01448 1.3e-109 ymfM S Helix-turn-helix domain
IGHPPKDA_01449 2e-129 IQ Enoyl-(Acyl carrier protein) reductase
IGHPPKDA_01450 3.4e-244 ymfH S Peptidase M16
IGHPPKDA_01451 4.2e-231 ymfF S Peptidase M16 inactive domain protein
IGHPPKDA_01452 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IGHPPKDA_01453 9.3e-71 WQ51_03320 S Protein of unknown function (DUF1149)
IGHPPKDA_01454 9.4e-97 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IGHPPKDA_01455 3.3e-155 rrmA 2.1.1.187 H Methyltransferase
IGHPPKDA_01456 5.7e-172 corA P CorA-like Mg2+ transporter protein
IGHPPKDA_01457 7.4e-191 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IGHPPKDA_01458 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IGHPPKDA_01459 2.1e-61 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IGHPPKDA_01460 1.6e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IGHPPKDA_01461 2.1e-143 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IGHPPKDA_01462 1.4e-113 cutC P Participates in the control of copper homeostasis
IGHPPKDA_01463 2.4e-203 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IGHPPKDA_01464 5.1e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
IGHPPKDA_01465 4.6e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IGHPPKDA_01466 1.3e-122 yjbM 2.7.6.5 S RelA SpoT domain protein
IGHPPKDA_01467 7.5e-106 yjbK S CYTH
IGHPPKDA_01468 1.1e-113 yjbH Q Thioredoxin
IGHPPKDA_01469 7.8e-44 coiA 3.6.4.12 S Competence protein
IGHPPKDA_01470 2.8e-148 coiA 3.6.4.12 S Competence protein
IGHPPKDA_01471 5.5e-245 XK27_08635 S UPF0210 protein
IGHPPKDA_01472 1e-38 gcvR T Belongs to the UPF0237 family
IGHPPKDA_01473 2.1e-257 cpdA S Calcineurin-like phosphoesterase
IGHPPKDA_01474 3.9e-234 malY 4.4.1.8 E Aminotransferase, class I
IGHPPKDA_01477 3.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IGHPPKDA_01478 1.4e-305 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
IGHPPKDA_01479 1.2e-288 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
IGHPPKDA_01480 5.3e-203 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IGHPPKDA_01481 6.2e-41 hol S Bacteriophage holin
IGHPPKDA_01482 3e-47
IGHPPKDA_01483 2.3e-38
IGHPPKDA_01484 3.9e-72
IGHPPKDA_01485 0.0 tcdA2 GT2,GT4 LM gp58-like protein
IGHPPKDA_01486 1e-122 S phage tail
IGHPPKDA_01487 0.0 D Phage tail tape measure protein
IGHPPKDA_01488 6.6e-60
IGHPPKDA_01489 5.1e-116
IGHPPKDA_01490 7.6e-67
IGHPPKDA_01491 1.4e-56
IGHPPKDA_01492 9.7e-58 S Phage head-tail joining protein
IGHPPKDA_01493 3.1e-53
IGHPPKDA_01495 2.5e-228 S Phage capsid family
IGHPPKDA_01496 3.2e-127 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
IGHPPKDA_01497 6.4e-232 S Phage portal protein
IGHPPKDA_01498 0.0 S overlaps another CDS with the same product name
IGHPPKDA_01499 1.6e-61
IGHPPKDA_01500 2.1e-69 V HNH endonuclease
IGHPPKDA_01502 3.7e-73
IGHPPKDA_01504 1.3e-38
IGHPPKDA_01505 4.6e-73 rusA L Endodeoxyribonuclease RusA
IGHPPKDA_01506 4.8e-105 S HNH endonuclease
IGHPPKDA_01508 6.3e-42
IGHPPKDA_01510 2.7e-154 dnaC L IstB-like ATP binding protein
IGHPPKDA_01511 8.2e-130 L Transcriptional regulator
IGHPPKDA_01512 3.8e-35 K Transcriptional regulator
IGHPPKDA_01513 2.5e-161 recT L RecT family
IGHPPKDA_01515 8.7e-167 yqaJ L YqaJ-like viral recombinase domain
IGHPPKDA_01518 1.1e-38 S Domain of unknown function (DUF771)
IGHPPKDA_01520 2.7e-74 K ORF6N domain
IGHPPKDA_01522 4.8e-17 ps115 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_01523 2.9e-16 E Zn peptidase
IGHPPKDA_01524 1.7e-73 kch J Ion transport protein
IGHPPKDA_01525 1.9e-17
IGHPPKDA_01526 3.3e-11
IGHPPKDA_01527 3e-72
IGHPPKDA_01528 8e-207 V Abi-like protein
IGHPPKDA_01529 3.5e-216 L Belongs to the 'phage' integrase family
IGHPPKDA_01531 2.8e-93 FNV0100 F NUDIX domain
IGHPPKDA_01532 4.8e-143 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IGHPPKDA_01533 4e-33 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
IGHPPKDA_01534 6.4e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IGHPPKDA_01535 2.2e-280 ytgP S Polysaccharide biosynthesis protein
IGHPPKDA_01536 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IGHPPKDA_01537 2.4e-119 3.6.1.27 I Acid phosphatase homologues
IGHPPKDA_01538 5.2e-109 S Domain of unknown function (DUF4811)
IGHPPKDA_01539 6.2e-266 lmrB EGP Major facilitator Superfamily
IGHPPKDA_01540 4.3e-80 merR K MerR HTH family regulatory protein
IGHPPKDA_01541 3.8e-263 emrY EGP Major facilitator Superfamily
IGHPPKDA_01542 3.3e-34 nusA K Participates in both transcription termination and antitermination
IGHPPKDA_01544 2.1e-54 S Phospholipase A2
IGHPPKDA_01546 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IGHPPKDA_01547 3.4e-74 rplI J Binds to the 23S rRNA
IGHPPKDA_01548 4.6e-247 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IGHPPKDA_01549 1.3e-218
IGHPPKDA_01550 5.9e-280 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IGHPPKDA_01551 6.9e-130 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IGHPPKDA_01552 8.7e-119 K Helix-turn-helix domain, rpiR family
IGHPPKDA_01553 5.4e-91 K Transcriptional regulator C-terminal region
IGHPPKDA_01554 2.9e-112 V ABC transporter, ATP-binding protein
IGHPPKDA_01555 1.1e-123 ylbB V ABC transporter permease
IGHPPKDA_01556 3.1e-258 ylbB V ABC transporter permease
IGHPPKDA_01557 2.7e-167 4.1.1.52 S Amidohydrolase
IGHPPKDA_01558 2.4e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IGHPPKDA_01559 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
IGHPPKDA_01560 1.1e-56 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
IGHPPKDA_01561 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
IGHPPKDA_01562 7.4e-158 lysR5 K LysR substrate binding domain
IGHPPKDA_01563 5.3e-201 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_01564 4.8e-34 S Phospholipase_D-nuclease N-terminal
IGHPPKDA_01565 6.4e-168 yxlF V ABC transporter
IGHPPKDA_01566 2.5e-130 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IGHPPKDA_01567 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IGHPPKDA_01568 2.4e-127
IGHPPKDA_01569 1.3e-100 K Bacteriophage CI repressor helix-turn-helix domain
IGHPPKDA_01570 3.6e-128
IGHPPKDA_01571 1.9e-15 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IGHPPKDA_01575 2.1e-188 M cysteine-type peptidase activity
IGHPPKDA_01576 0.0 trsE S COG0433 Predicted ATPase
IGHPPKDA_01577 2.4e-104
IGHPPKDA_01579 2.3e-266 5.4.99.21 S domain, Protein
IGHPPKDA_01580 0.0 U TraM recognition site of TraD and TraG
IGHPPKDA_01583 7.3e-201 M Domain of unknown function (DUF5011)
IGHPPKDA_01584 1.9e-204
IGHPPKDA_01585 5.2e-31
IGHPPKDA_01591 1.7e-12 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IGHPPKDA_01593 2.5e-56 M Psort location Cellwall, score
IGHPPKDA_01594 3.2e-22 M Peptidase_C39 like family
IGHPPKDA_01595 2.4e-53 M Peptidase_C39 like family
IGHPPKDA_01602 6.7e-81 repA S Replication initiator protein A
IGHPPKDA_01603 9.3e-102 soj D AAA domain
IGHPPKDA_01604 5.8e-14
IGHPPKDA_01605 1.3e-20
IGHPPKDA_01606 7.7e-172 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
IGHPPKDA_01607 6.8e-23
IGHPPKDA_01608 1.5e-12
IGHPPKDA_01610 1.7e-30 2.1.1.37 H C-5 cytosine-specific DNA methylase
IGHPPKDA_01611 3.1e-37 L Transposase
IGHPPKDA_01612 2.1e-85 tnp2PF3 L Transposase
IGHPPKDA_01613 8.2e-40
IGHPPKDA_01614 1.6e-76 O OsmC-like protein
IGHPPKDA_01615 7e-278 lsa S ABC transporter
IGHPPKDA_01616 5.1e-113 ylbE GM NAD(P)H-binding
IGHPPKDA_01617 1.7e-156 yeaE S Aldo/keto reductase family
IGHPPKDA_01618 4.8e-249 yifK E Amino acid permease
IGHPPKDA_01619 2.7e-241 S Protein of unknown function (DUF3800)
IGHPPKDA_01620 0.0 yjcE P Sodium proton antiporter
IGHPPKDA_01621 9.6e-44 S Protein of unknown function (DUF3021)
IGHPPKDA_01622 1.7e-73 K LytTr DNA-binding domain
IGHPPKDA_01623 2.3e-148 cylB V ABC-2 type transporter
IGHPPKDA_01624 7e-164 cylA V ABC transporter
IGHPPKDA_01625 7.5e-146 S Alpha/beta hydrolase of unknown function (DUF915)
IGHPPKDA_01626 1.2e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
IGHPPKDA_01627 2.6e-52 ybjQ S Belongs to the UPF0145 family
IGHPPKDA_01628 4.8e-160 3.5.1.10 C nadph quinone reductase
IGHPPKDA_01629 2.8e-246 amt P ammonium transporter
IGHPPKDA_01630 2.4e-178 yfeX P Peroxidase
IGHPPKDA_01631 2e-118 yhiD S MgtC family
IGHPPKDA_01632 5.5e-115 F DNA RNA non-specific endonuclease
IGHPPKDA_01633 0.0 ybiT S ABC transporter, ATP-binding protein
IGHPPKDA_01634 0.0 mutS L ATPase domain of DNA mismatch repair MUTS family
IGHPPKDA_01635 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
IGHPPKDA_01636 2.6e-129 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IGHPPKDA_01637 1e-302 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
IGHPPKDA_01638 7.2e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IGHPPKDA_01639 7.8e-108 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
IGHPPKDA_01640 4.5e-35 V ATPase activity
IGHPPKDA_01641 2e-35 oppF P Oligopeptide/dipeptide transporter, C-terminal region
IGHPPKDA_01642 6e-35 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IGHPPKDA_01643 4.1e-59
IGHPPKDA_01644 0.0 pepF E Oligopeptidase F
IGHPPKDA_01645 1.6e-291 V ABC transporter transmembrane region
IGHPPKDA_01646 3.7e-171 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_01647 5.5e-86 C FMN binding
IGHPPKDA_01648 1.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IGHPPKDA_01649 3.2e-170 mleP S Sodium Bile acid symporter family
IGHPPKDA_01650 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IGHPPKDA_01651 1.5e-155 mleR K LysR family
IGHPPKDA_01652 1.3e-173 corA P CorA-like Mg2+ transporter protein
IGHPPKDA_01653 5.7e-61 yeaO S Protein of unknown function, DUF488
IGHPPKDA_01654 1.6e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IGHPPKDA_01655 3.2e-71
IGHPPKDA_01656 1.9e-88 ywrF S Flavin reductase like domain
IGHPPKDA_01657 2.1e-166 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IGHPPKDA_01658 2.7e-45
IGHPPKDA_01659 1.5e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IGHPPKDA_01660 3.1e-24
IGHPPKDA_01661 3.2e-209 yubA S AI-2E family transporter
IGHPPKDA_01662 7.5e-80
IGHPPKDA_01663 3.1e-54
IGHPPKDA_01665 3.1e-192 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IGHPPKDA_01666 8.7e-42
IGHPPKDA_01667 1.2e-41 ygbF S Sugar efflux transporter for intercellular exchange
IGHPPKDA_01668 1.5e-58 K Transcriptional regulator PadR-like family
IGHPPKDA_01669 2.8e-188 K DNA-binding helix-turn-helix protein
IGHPPKDA_01672 1.3e-22 S Bacteriophage abortive infection AbiH
IGHPPKDA_01673 1.8e-44 S Phage gp6-like head-tail connector protein
IGHPPKDA_01674 4.8e-269 S Phage capsid family
IGHPPKDA_01675 2.4e-44 S Phage portal protein
IGHPPKDA_01676 3e-142 S Phage portal protein
IGHPPKDA_01678 6.1e-31 sip L Belongs to the 'phage' integrase family
IGHPPKDA_01679 2.2e-38 KT PspC domain protein
IGHPPKDA_01680 6.2e-114 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
IGHPPKDA_01681 1.3e-179 oppF P Belongs to the ABC transporter superfamily
IGHPPKDA_01682 1.1e-197 oppD P Belongs to the ABC transporter superfamily
IGHPPKDA_01683 2.5e-178 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGHPPKDA_01684 8e-163 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IGHPPKDA_01685 2e-302 oppA E ABC transporter, substratebinding protein
IGHPPKDA_01686 4.9e-252 EGP Major facilitator Superfamily
IGHPPKDA_01687 1.3e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IGHPPKDA_01688 6.2e-131 yrjD S LUD domain
IGHPPKDA_01689 5.8e-288 lutB C 4Fe-4S dicluster domain
IGHPPKDA_01690 3.3e-149 lutA C Cysteine-rich domain
IGHPPKDA_01691 4.5e-84
IGHPPKDA_01692 2.2e-51 chbA 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
IGHPPKDA_01693 1.1e-208 S Bacterial protein of unknown function (DUF871)
IGHPPKDA_01694 1.8e-69 S Domain of unknown function (DUF3284)
IGHPPKDA_01696 2.9e-265 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGHPPKDA_01698 0.0 rafA 3.2.1.22 G alpha-galactosidase
IGHPPKDA_01699 5.3e-133 S Belongs to the UPF0246 family
IGHPPKDA_01700 2e-135 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
IGHPPKDA_01701 0.0 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
IGHPPKDA_01702 6.4e-81
IGHPPKDA_01703 4.9e-60 S WxL domain surface cell wall-binding
IGHPPKDA_01704 3.9e-145 frlD 2.7.1.218 G pfkB family carbohydrate kinase
IGHPPKDA_01705 6.2e-42
IGHPPKDA_01706 1.3e-46 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IGHPPKDA_01707 1.7e-44 G PTS system fructose IIA component
IGHPPKDA_01708 5.6e-144 agaD G PTS system mannose/fructose/sorbose family IID component
IGHPPKDA_01709 1.8e-142 G PTS system sorbose-specific iic component
IGHPPKDA_01710 6e-88 agaV 2.7.1.191 G PTS system sorbose subfamily IIB component
IGHPPKDA_01711 3.6e-232 ugl 3.2.1.180 GH88 S Glycosyl Hydrolase Family 88
IGHPPKDA_01712 2e-157 Z012_03480 S Psort location Cytoplasmic, score
IGHPPKDA_01713 1.1e-138 K Bacterial transcriptional regulator
IGHPPKDA_01714 2.1e-162 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IGHPPKDA_01715 8.2e-151 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IGHPPKDA_01716 1.6e-117 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
IGHPPKDA_01717 5.1e-195 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
IGHPPKDA_01718 2e-120 alkD L DNA alkylation repair enzyme
IGHPPKDA_01719 7.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IGHPPKDA_01720 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IGHPPKDA_01721 3.7e-171 ykoT GT2 M Glycosyl transferase family 2
IGHPPKDA_01722 2.6e-118 lssY 3.6.1.27 I phosphatase
IGHPPKDA_01723 4.1e-113 dedA S SNARE-like domain protein
IGHPPKDA_01725 4.9e-241 T PhoQ Sensor
IGHPPKDA_01726 1.1e-124 K Transcriptional regulatory protein, C terminal
IGHPPKDA_01728 1.5e-17
IGHPPKDA_01729 9.2e-272 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
IGHPPKDA_01730 3.2e-292 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
IGHPPKDA_01731 6e-305 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
IGHPPKDA_01732 5e-246 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
IGHPPKDA_01733 0.0
IGHPPKDA_01736 3e-68
IGHPPKDA_01737 6.1e-20
IGHPPKDA_01738 1.4e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
IGHPPKDA_01739 1.9e-251 M domain protein
IGHPPKDA_01740 1.2e-70
IGHPPKDA_01741 1.7e-111 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
IGHPPKDA_01742 1.2e-117 GM NmrA-like family
IGHPPKDA_01743 1.5e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
IGHPPKDA_01744 5e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IGHPPKDA_01745 2.5e-275 aldA 1.2.1.21, 1.2.1.22 C Belongs to the aldehyde dehydrogenase family
IGHPPKDA_01746 3.4e-132 mntB 3.6.3.35 P AAA domain, putative AbiEii toxin, Type IV TA system
IGHPPKDA_01747 3.6e-144 mtsB U ABC 3 transport family
IGHPPKDA_01748 7.6e-177 sitA P Belongs to the bacterial solute-binding protein 9 family
IGHPPKDA_01749 1.2e-52 czrA K Transcriptional regulator, ArsR family
IGHPPKDA_01750 1.4e-110 2.5.1.105 P Cation efflux family
IGHPPKDA_01751 1.2e-25
IGHPPKDA_01752 0.0 mco Q Multicopper oxidase
IGHPPKDA_01753 2.1e-239 EGP Major Facilitator Superfamily
IGHPPKDA_01754 4.9e-55
IGHPPKDA_01755 0.0 pacL P P-type ATPase
IGHPPKDA_01756 3.2e-260 mntH P H( )-stimulated, divalent metal cation uptake system
IGHPPKDA_01757 4.5e-20
IGHPPKDA_01758 5.9e-125 S Putative transposase
IGHPPKDA_01759 3.8e-35 L Transposase and inactivated derivatives
IGHPPKDA_01760 1.2e-40 dpiA KT cheY-homologous receiver domain
IGHPPKDA_01761 2.5e-286 dpiB 2.7.13.3 T Single cache domain 3
IGHPPKDA_01762 4e-224 maeN C 2-hydroxycarboxylate transporter family
IGHPPKDA_01763 5.3e-212 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
IGHPPKDA_01764 2.2e-35 yjdF S Protein of unknown function (DUF2992)
IGHPPKDA_01765 4.3e-114 S Bacteriocin-protection, YdeI or OmpD-Associated
IGHPPKDA_01766 2.3e-254 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
IGHPPKDA_01767 7.6e-146 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
IGHPPKDA_01768 4.8e-90 maa 2.3.1.79 S Maltose acetyltransferase
IGHPPKDA_01769 1.1e-214 lsgC M Glycosyl transferases group 1
IGHPPKDA_01770 2.5e-308 yebA E Transglutaminase/protease-like homologues
IGHPPKDA_01771 1.2e-52 yeaD S Protein of unknown function DUF58
IGHPPKDA_01772 2.9e-119 yeaD S Protein of unknown function DUF58
IGHPPKDA_01773 4.6e-142 yeaC S ATPase family associated with various cellular activities (AAA)
IGHPPKDA_01774 1e-105 S Stage II sporulation protein M
IGHPPKDA_01775 1.1e-98 ydaF J Acetyltransferase (GNAT) domain
IGHPPKDA_01776 2.1e-266 glnP P ABC transporter
IGHPPKDA_01777 1.5e-264 glnP P ABC transporter
IGHPPKDA_01778 7.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IGHPPKDA_01779 9.5e-166 yniA G Phosphotransferase enzyme family
IGHPPKDA_01780 2.4e-144 S AAA ATPase domain
IGHPPKDA_01781 9.7e-270 ydbT S Bacterial PH domain
IGHPPKDA_01782 1e-68 S Bacterial PH domain
IGHPPKDA_01783 3.4e-52
IGHPPKDA_01784 9.7e-186 tdcB 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IGHPPKDA_01785 7.7e-293 S OPT oligopeptide transporter protein
IGHPPKDA_01786 1.2e-61 S Coenzyme PQQ synthesis protein D (PqqD)
IGHPPKDA_01787 2.6e-92 pipD E Dipeptidase
IGHPPKDA_01788 8.2e-156 pipD E Dipeptidase
IGHPPKDA_01789 4.7e-257 gor 1.8.1.7 C Glutathione reductase
IGHPPKDA_01790 2.5e-248 lmrB EGP Major facilitator Superfamily
IGHPPKDA_01791 9.4e-98 yxaF K Bacterial regulatory proteins, tetR family
IGHPPKDA_01792 6.2e-295 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IGHPPKDA_01793 6.7e-301 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IGHPPKDA_01794 2.2e-17 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IGHPPKDA_01795 2.8e-154 licT K CAT RNA binding domain
IGHPPKDA_01796 1.5e-289 cydC V ABC transporter transmembrane region
IGHPPKDA_01797 0.0 cydD CO ABC transporter transmembrane region
IGHPPKDA_01798 1.2e-73 S NusG domain II
IGHPPKDA_01799 2.8e-154 M Peptidoglycan-binding domain 1 protein
IGHPPKDA_01800 1.4e-111 S CRISPR-associated protein (Cas_Csn2)
IGHPPKDA_01801 1.6e-46 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IGHPPKDA_01802 3.1e-167 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IGHPPKDA_01803 1.1e-307 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IGHPPKDA_01804 1.4e-44 tnp2PF3 L Transposase DDE domain
IGHPPKDA_01805 6e-61
IGHPPKDA_01806 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IGHPPKDA_01807 3.9e-298 hsdM 2.1.1.72 V type I restriction-modification system
IGHPPKDA_01808 1.8e-111 3.1.21.3 V type I restriction modification DNA specificity domain protein
IGHPPKDA_01809 2.3e-26
IGHPPKDA_01810 3.9e-196 L Psort location Cytoplasmic, score
IGHPPKDA_01811 1.4e-30
IGHPPKDA_01812 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IGHPPKDA_01813 3.4e-65
IGHPPKDA_01814 2.3e-148
IGHPPKDA_01815 5.2e-63
IGHPPKDA_01816 1.3e-261 traK U TraM recognition site of TraD and TraG
IGHPPKDA_01817 1.6e-79
IGHPPKDA_01818 8.4e-63 CO COG0526, thiol-disulfide isomerase and thioredoxins
IGHPPKDA_01819 1e-89
IGHPPKDA_01820 2e-211 M CHAP domain
IGHPPKDA_01821 5.1e-233 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
IGHPPKDA_01822 0.0 traE U type IV secretory pathway VirB4
IGHPPKDA_01823 1.4e-116
IGHPPKDA_01824 8.6e-36
IGHPPKDA_01825 1.3e-51 S Cag pathogenicity island, type IV secretory system
IGHPPKDA_01826 1.1e-104
IGHPPKDA_01827 1.4e-50
IGHPPKDA_01828 1.1e-128 L MobA MobL family protein
IGHPPKDA_01829 2.6e-205 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IGHPPKDA_01830 1.3e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IGHPPKDA_01831 3.4e-112 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IGHPPKDA_01832 3.9e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IGHPPKDA_01833 1.8e-104 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IGHPPKDA_01834 3.3e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IGHPPKDA_01835 3e-125 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IGHPPKDA_01836 2.7e-132 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IGHPPKDA_01837 1.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IGHPPKDA_01838 7.1e-53 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
IGHPPKDA_01839 3.8e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IGHPPKDA_01840 3.7e-111 nfnB 1.5.1.34 C Nitroreductase family
IGHPPKDA_01841 2.6e-70 K Acetyltransferase (GNAT) domain
IGHPPKDA_01842 3.4e-32 msi198 K Acetyltransferase (GNAT) domain
IGHPPKDA_01843 2.9e-170 EGP Transmembrane secretion effector
IGHPPKDA_01844 7.2e-124 T Transcriptional regulatory protein, C terminal
IGHPPKDA_01845 3.8e-176 T PhoQ Sensor
IGHPPKDA_01846 1.8e-136 XK27_05695 V ABC transporter, ATP-binding protein
IGHPPKDA_01847 0.0 ysaB V FtsX-like permease family
IGHPPKDA_01848 8.1e-39
IGHPPKDA_01849 1.2e-210 xerS L Belongs to the 'phage' integrase family
IGHPPKDA_01850 2e-169 ppaC 3.6.1.1 C inorganic pyrophosphatase
IGHPPKDA_01851 3.4e-180 K LysR substrate binding domain
IGHPPKDA_01852 5.6e-171 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IGHPPKDA_01853 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
IGHPPKDA_01854 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IGHPPKDA_01855 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IGHPPKDA_01856 1.7e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IGHPPKDA_01857 6.9e-172 lacX 5.1.3.3 G Aldose 1-epimerase
IGHPPKDA_01858 1.2e-258 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IGHPPKDA_01859 7.2e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IGHPPKDA_01860 2.1e-168 xerC D Belongs to the 'phage' integrase family. XerC subfamily
IGHPPKDA_01861 5.2e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IGHPPKDA_01862 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IGHPPKDA_01863 5.1e-145 dprA LU DNA protecting protein DprA
IGHPPKDA_01864 1.1e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IGHPPKDA_01865 1.9e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IGHPPKDA_01866 4.5e-49 K Helix-turn-helix domain
IGHPPKDA_01867 5.7e-248 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IGHPPKDA_01868 1.1e-39 yozE S Belongs to the UPF0346 family
IGHPPKDA_01869 5e-84 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IGHPPKDA_01870 3e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
IGHPPKDA_01871 4.5e-152 ypmR E GDSL-like Lipase/Acylhydrolase
IGHPPKDA_01872 2.5e-145 DegV S EDD domain protein, DegV family
IGHPPKDA_01873 2.1e-114 hly S protein, hemolysin III
IGHPPKDA_01874 5.7e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IGHPPKDA_01875 2.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IGHPPKDA_01876 0.0 yfmR S ABC transporter, ATP-binding protein
IGHPPKDA_01877 1.3e-84
IGHPPKDA_01878 3.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IGHPPKDA_01879 2.6e-147 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IGHPPKDA_01880 2.3e-237 S Tetratricopeptide repeat protein
IGHPPKDA_01881 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IGHPPKDA_01882 1e-243 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IGHPPKDA_01883 2.1e-225 rpsA 1.17.7.4 J Ribosomal protein S1
IGHPPKDA_01884 2e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IGHPPKDA_01885 6.1e-66 M Lysin motif
IGHPPKDA_01886 3.2e-264 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
IGHPPKDA_01887 5.3e-181 ypbB 5.1.3.1 S Helix-turn-helix domain
IGHPPKDA_01888 2.7e-44 fer C 4Fe-4S single cluster domain of Ferredoxin I
IGHPPKDA_01889 2.6e-95 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IGHPPKDA_01890 6.7e-136 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IGHPPKDA_01891 5.5e-107 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IGHPPKDA_01892 1.2e-124 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IGHPPKDA_01893 2e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IGHPPKDA_01894 1.4e-164 xerD D recombinase XerD
IGHPPKDA_01895 1.1e-161 cvfB S S1 domain
IGHPPKDA_01896 1.5e-72 yeaL S Protein of unknown function (DUF441)
IGHPPKDA_01897 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IGHPPKDA_01898 7e-178 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IGHPPKDA_01899 0.0 dnaE 2.7.7.7 L DNA polymerase
IGHPPKDA_01900 2.5e-18 S Protein of unknown function (DUF2929)
IGHPPKDA_01901 1.3e-125
IGHPPKDA_01902 3.9e-303 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
IGHPPKDA_01903 2.8e-94 M1-874 K Domain of unknown function (DUF1836)
IGHPPKDA_01904 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IGHPPKDA_01905 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IGHPPKDA_01906 4.1e-48 yrvD S Lipopolysaccharide assembly protein A domain
IGHPPKDA_01907 3e-142 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
IGHPPKDA_01908 7.3e-183 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IGHPPKDA_01909 0.0 oatA I Acyltransferase
IGHPPKDA_01910 6.4e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IGHPPKDA_01911 6.6e-131 fruR K DeoR C terminal sensor domain
IGHPPKDA_01912 6.7e-170 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IGHPPKDA_01913 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
IGHPPKDA_01914 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IGHPPKDA_01915 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IGHPPKDA_01916 1.5e-259 arpJ P ABC transporter permease
IGHPPKDA_01917 1.3e-20
IGHPPKDA_01918 7.8e-48 MA20_27270 S mazG nucleotide pyrophosphohydrolase
IGHPPKDA_01919 3.1e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
IGHPPKDA_01920 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IGHPPKDA_01921 8.4e-222 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IGHPPKDA_01922 3.6e-297 yknV V ABC transporter
IGHPPKDA_01923 2.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IGHPPKDA_01924 2.2e-165 S Tetratricopeptide repeat
IGHPPKDA_01925 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IGHPPKDA_01926 1.1e-50
IGHPPKDA_01927 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IGHPPKDA_01929 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
IGHPPKDA_01930 4.9e-169 holA 2.7.7.7 L DNA polymerase III delta subunit
IGHPPKDA_01931 0.0 comEC S Competence protein ComEC
IGHPPKDA_01932 2.5e-113 comEA L Competence protein ComEA
IGHPPKDA_01933 3.8e-182 ylbL T Belongs to the peptidase S16 family
IGHPPKDA_01934 1.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IGHPPKDA_01935 2.5e-98 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IGHPPKDA_01936 1.6e-61 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IGHPPKDA_01937 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IGHPPKDA_01938 2.2e-210 ftsW D Belongs to the SEDS family
IGHPPKDA_01939 1.6e-165 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
IGHPPKDA_01940 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IGHPPKDA_01941 0.0 XK27_09600 V ABC transporter, ATP-binding protein
IGHPPKDA_01942 0.0 V ABC transporter
IGHPPKDA_01943 6e-222 oxlT P Major Facilitator Superfamily
IGHPPKDA_01944 7.7e-129 treR K UTRA
IGHPPKDA_01945 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
IGHPPKDA_01946 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IGHPPKDA_01947 3.6e-217 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IGHPPKDA_01948 2.1e-266 yfnA E Amino Acid
IGHPPKDA_01949 3e-173 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
IGHPPKDA_01950 4.6e-252 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IGHPPKDA_01951 4.6e-31 K 'Cold-shock' DNA-binding domain
IGHPPKDA_01952 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
IGHPPKDA_01953 1.4e-144 3.5.2.6 V Beta-lactamase enzyme family
IGHPPKDA_01954 2.8e-191 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IGHPPKDA_01955 6.7e-195 blaA6 V Beta-lactamase
IGHPPKDA_01956 1.7e-154 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IGHPPKDA_01957 7.6e-161 ybbH_2 K Helix-turn-helix domain, rpiR family
IGHPPKDA_01958 3.1e-81 2.7.1.191 G PTS system sorbose subfamily IIB component
IGHPPKDA_01959 8.3e-151 G PTS system mannose/fructose/sorbose family IID component
IGHPPKDA_01960 3.1e-129 G PTS system sorbose-specific iic component
IGHPPKDA_01961 7e-203 S endonuclease exonuclease phosphatase family protein
IGHPPKDA_01962 3.9e-173 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IGHPPKDA_01963 1.5e-114 Q Methyltransferase
IGHPPKDA_01964 1.7e-51 sugE U Multidrug resistance protein
IGHPPKDA_01965 1.1e-121 S -acetyltransferase
IGHPPKDA_01966 4.7e-93 MA20_25245 K FR47-like protein
IGHPPKDA_01967 7.6e-132 S Metal-independent alpha-mannosidase (GH125)
IGHPPKDA_01968 0.0 mngB 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
IGHPPKDA_01969 2.2e-159 mngB 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
IGHPPKDA_01970 3.7e-238 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGHPPKDA_01971 7.2e-135 K UbiC transcription regulator-associated domain protein
IGHPPKDA_01972 1e-136 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
IGHPPKDA_01974 5.3e-247 pts36C G PTS system sugar-specific permease component
IGHPPKDA_01975 2.1e-13 sgcB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_01976 2.1e-79 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IGHPPKDA_01977 2.7e-143 K DeoR C terminal sensor domain
IGHPPKDA_01978 1.8e-161 J Methyltransferase domain
IGHPPKDA_01979 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IGHPPKDA_01982 0.0 M Heparinase II/III N-terminus
IGHPPKDA_01984 2.3e-28 G PTS system fructose IIA component
IGHPPKDA_01985 1.7e-44 nylA 3.5.1.4 J Belongs to the amidase family
IGHPPKDA_01986 2.3e-41 treR K UTRA
IGHPPKDA_01988 3.6e-37
IGHPPKDA_01989 1.7e-42 S Protein of unknown function (DUF2089)
IGHPPKDA_01990 1.4e-181 I PAP2 superfamily
IGHPPKDA_01991 3.6e-207 mccF V LD-carboxypeptidase
IGHPPKDA_01992 4.3e-42
IGHPPKDA_01993 4e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IGHPPKDA_01994 2e-88 ogt 2.1.1.63 L Methyltransferase
IGHPPKDA_01995 8e-193 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGHPPKDA_01996 8.6e-42
IGHPPKDA_01997 3.6e-80 slyA K Transcriptional regulator
IGHPPKDA_01998 4.7e-163 1.6.5.5 C alcohol dehydrogenase
IGHPPKDA_01999 4.8e-55 ypaA S Protein of unknown function (DUF1304)
IGHPPKDA_02000 5.2e-54 S Protein of unknown function (DUF1516)
IGHPPKDA_02001 9.1e-254 pbuO S permease
IGHPPKDA_02002 4.1e-45 S DsrE/DsrF-like family
IGHPPKDA_02003 3.5e-177 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IGHPPKDA_02004 1.9e-28
IGHPPKDA_02005 3.1e-104 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IGHPPKDA_02006 0.0
IGHPPKDA_02008 1.3e-121 S WxL domain surface cell wall-binding
IGHPPKDA_02009 7.6e-58
IGHPPKDA_02010 2.2e-128 fhuC 3.6.3.35 P ABC transporter
IGHPPKDA_02011 4.4e-133 znuB U ABC 3 transport family
IGHPPKDA_02012 3.5e-165 T Calcineurin-like phosphoesterase superfamily domain
IGHPPKDA_02013 4.2e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
IGHPPKDA_02014 0.0 pepF E oligoendopeptidase F
IGHPPKDA_02015 1.7e-188 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IGHPPKDA_02016 2.9e-249 brnQ U Component of the transport system for branched-chain amino acids
IGHPPKDA_02017 1.6e-70 T Sh3 type 3 domain protein
IGHPPKDA_02018 1.1e-133 glcR K DeoR C terminal sensor domain
IGHPPKDA_02019 2e-146 M Glycosyltransferase like family 2
IGHPPKDA_02020 8.8e-136 XK27_06755 S Protein of unknown function (DUF975)
IGHPPKDA_02021 5.3e-40
IGHPPKDA_02022 1.1e-107 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IGHPPKDA_02023 2.7e-174 draG O ADP-ribosylglycohydrolase
IGHPPKDA_02024 4.3e-294 S ABC transporter
IGHPPKDA_02025 1.4e-133 Q Methyltransferase domain
IGHPPKDA_02026 3.8e-34 L Exonuclease
IGHPPKDA_02029 4.7e-110 usp 3.5.1.28 CBM50 D CHAP domain
IGHPPKDA_02030 0.0 ylbB V ABC transporter permease
IGHPPKDA_02031 2.8e-128 macB V ABC transporter, ATP-binding protein
IGHPPKDA_02032 5.4e-98 K transcriptional regulator
IGHPPKDA_02033 5.9e-154 supH G Sucrose-6F-phosphate phosphohydrolase
IGHPPKDA_02034 3e-48
IGHPPKDA_02035 1.4e-123 S membrane transporter protein
IGHPPKDA_02036 2.6e-101 S Protein of unknown function (DUF1211)
IGHPPKDA_02037 9.1e-164 corA P CorA-like Mg2+ transporter protein
IGHPPKDA_02038 1.2e-112 K Bacterial regulatory proteins, tetR family
IGHPPKDA_02040 3.4e-242 mntH P H( )-stimulated, divalent metal cation uptake system
IGHPPKDA_02041 7.8e-55
IGHPPKDA_02043 6.8e-286 pipD E Dipeptidase
IGHPPKDA_02044 3.1e-105 S Membrane
IGHPPKDA_02045 1.1e-102
IGHPPKDA_02047 6.1e-103 V ABC transporter
IGHPPKDA_02048 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IGHPPKDA_02049 8.8e-69 2.7.1.191 G PTS system fructose IIA component
IGHPPKDA_02050 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IGHPPKDA_02051 2.4e-153 G PTS system mannose/fructose/sorbose family IID component
IGHPPKDA_02052 2.8e-127 G PTS system sorbose-specific iic component
IGHPPKDA_02053 3e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
IGHPPKDA_02054 1.6e-185 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
IGHPPKDA_02055 1.9e-43 S Bacterial toxin of type II toxin-antitoxin system, YafQ
IGHPPKDA_02056 4.8e-151 S hydrolase
IGHPPKDA_02057 1e-262 npr 1.11.1.1 C NADH oxidase
IGHPPKDA_02058 1.1e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IGHPPKDA_02059 6.5e-185 hrtB V ABC transporter permease
IGHPPKDA_02060 8.7e-87 ygfC K Bacterial regulatory proteins, tetR family
IGHPPKDA_02061 1.3e-137 3.2.1.17 M hydrolase, family 25
IGHPPKDA_02062 1.1e-11 S YvrJ protein family
IGHPPKDA_02064 2.1e-94 kgtP EGP Sugar (and other) transporter
IGHPPKDA_02065 9.4e-66 kgtP EGP Sugar (and other) transporter
IGHPPKDA_02067 4.5e-51
IGHPPKDA_02068 7.3e-161 K Transcriptional activator, Rgg GadR MutR family
IGHPPKDA_02069 3.7e-285 V ABC-type multidrug transport system, ATPase and permease components
IGHPPKDA_02070 9.8e-242 EGP Major facilitator Superfamily
IGHPPKDA_02071 1.6e-49 K TRANSCRIPTIONal
IGHPPKDA_02072 0.0 ydgH S MMPL family
IGHPPKDA_02073 7.4e-109 K Tetracycline repressor, C-terminal all-alpha domain
IGHPPKDA_02075 3.3e-110 opuCD P Binding-protein-dependent transport system inner membrane component
IGHPPKDA_02076 3.3e-172 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IGHPPKDA_02077 1e-105 opuCB E ABC transporter permease
IGHPPKDA_02078 7.2e-215 opuCA 2.7.7.7 E ABC transporter, ATP-binding protein
IGHPPKDA_02079 6.7e-23 ypbD S CAAX protease self-immunity
IGHPPKDA_02081 2.9e-39
IGHPPKDA_02082 1.7e-109 V ATPases associated with a variety of cellular activities
IGHPPKDA_02084 4.8e-48
IGHPPKDA_02085 3.9e-58 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
IGHPPKDA_02086 1.5e-16
IGHPPKDA_02087 1.9e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IGHPPKDA_02088 1.8e-167 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IGHPPKDA_02089 2.8e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IGHPPKDA_02090 2.1e-70 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IGHPPKDA_02091 1.2e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IGHPPKDA_02092 2.9e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
IGHPPKDA_02093 3.3e-186 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IGHPPKDA_02094 7e-195 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IGHPPKDA_02095 2.5e-62
IGHPPKDA_02096 4.5e-73 3.6.1.55 L NUDIX domain
IGHPPKDA_02097 7.5e-147 EG EamA-like transporter family
IGHPPKDA_02099 6.3e-83
IGHPPKDA_02100 1.1e-28 S Protein of unknown function (DUF2785)
IGHPPKDA_02101 2.6e-63 S Protein of unknown function (DUF2785)
IGHPPKDA_02103 1.1e-19 S ABC transporter
IGHPPKDA_02104 2e-80 S ABC transporter
IGHPPKDA_02105 3.8e-134 S ABC-2 family transporter protein
IGHPPKDA_02106 2.8e-132 S ABC-2 family transporter protein
IGHPPKDA_02107 2.1e-146 ssuC U Binding-protein-dependent transport system inner membrane component
IGHPPKDA_02108 3.6e-115 ssuB P ATPases associated with a variety of cellular activities
IGHPPKDA_02109 4.9e-232 yfiQ I Acyltransferase family
IGHPPKDA_02110 1.7e-290 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
IGHPPKDA_02111 6.2e-174 ssuA P NMT1-like family
IGHPPKDA_02112 5e-145 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
IGHPPKDA_02113 3e-134 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
IGHPPKDA_02114 7.5e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IGHPPKDA_02115 2.3e-157 phnD P Phosphonate ABC transporter
IGHPPKDA_02117 1.5e-88 XK27_02675 K Acetyltransferase (GNAT) domain
IGHPPKDA_02118 1.2e-48
IGHPPKDA_02119 8.2e-19
IGHPPKDA_02120 3.8e-66 S Protein of unknown function (DUF1093)
IGHPPKDA_02121 5.3e-37
IGHPPKDA_02122 2.5e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IGHPPKDA_02123 3.2e-86 XK27_03960 S Protein of unknown function (DUF3013)
IGHPPKDA_02124 1.2e-174 prmA J Ribosomal protein L11 methyltransferase
IGHPPKDA_02125 5.9e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IGHPPKDA_02126 1.3e-43
IGHPPKDA_02127 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IGHPPKDA_02128 2.7e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IGHPPKDA_02129 2.6e-117 3.1.3.18 J HAD-hyrolase-like
IGHPPKDA_02130 2e-244 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
IGHPPKDA_02131 7.9e-84 FG adenosine 5'-monophosphoramidase activity
IGHPPKDA_02132 1.6e-157 V ABC transporter
IGHPPKDA_02133 9e-281
IGHPPKDA_02134 3e-148 K Helix-turn-helix
IGHPPKDA_02135 2.1e-76
IGHPPKDA_02136 3.1e-167 1.6.5.5 C nadph quinone reductase
IGHPPKDA_02137 1.7e-35 XK27_04345 3.6.1.1 C Inorganic pyrophosphatase
IGHPPKDA_02138 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
IGHPPKDA_02139 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IGHPPKDA_02140 2.6e-82 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IGHPPKDA_02141 1.7e-168 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IGHPPKDA_02142 1.1e-164 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IGHPPKDA_02143 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IGHPPKDA_02144 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IGHPPKDA_02145 6.1e-68 yqeY S YqeY-like protein
IGHPPKDA_02147 5.9e-180 phoH T phosphate starvation-inducible protein PhoH
IGHPPKDA_02148 9.1e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IGHPPKDA_02149 3.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IGHPPKDA_02150 8e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IGHPPKDA_02151 6.6e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IGHPPKDA_02152 5.9e-143 recO L Involved in DNA repair and RecF pathway recombination
IGHPPKDA_02153 6.4e-56
IGHPPKDA_02154 3.2e-55
IGHPPKDA_02155 2e-171 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IGHPPKDA_02156 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IGHPPKDA_02157 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IGHPPKDA_02158 3.4e-188 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IGHPPKDA_02159 9.2e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
IGHPPKDA_02160 6e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IGHPPKDA_02161 3.5e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IGHPPKDA_02162 8.2e-60 yitW S Iron-sulfur cluster assembly protein
IGHPPKDA_02163 2.5e-143
IGHPPKDA_02164 9.4e-175
IGHPPKDA_02165 2.1e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
IGHPPKDA_02166 4.9e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IGHPPKDA_02167 2.1e-180 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IGHPPKDA_02168 1.7e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IGHPPKDA_02169 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IGHPPKDA_02170 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IGHPPKDA_02171 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IGHPPKDA_02172 1e-11 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IGHPPKDA_02173 7.1e-86 ypmB S Protein conserved in bacteria
IGHPPKDA_02174 3.4e-219 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IGHPPKDA_02175 1.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IGHPPKDA_02176 1.8e-113 dnaD L DnaD domain protein
IGHPPKDA_02177 2.3e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IGHPPKDA_02178 4.4e-85 comEB 3.5.4.12 F ComE operon protein 2
IGHPPKDA_02179 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IGHPPKDA_02180 5.1e-121 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IGHPPKDA_02181 1.3e-107 ypsA S Belongs to the UPF0398 family
IGHPPKDA_02182 2.3e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IGHPPKDA_02184 7.5e-219 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IGHPPKDA_02185 1.2e-174 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IGHPPKDA_02186 3.9e-34
IGHPPKDA_02187 7.4e-194 lplA 6.3.1.20 H Lipoate-protein ligase
IGHPPKDA_02188 0.0 pepO 3.4.24.71 O Peptidase family M13
IGHPPKDA_02189 9.7e-166 K Transcriptional regulator
IGHPPKDA_02190 2.4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGHPPKDA_02191 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGHPPKDA_02192 2e-38 nrdH O Glutaredoxin
IGHPPKDA_02193 1.1e-275 S Mga helix-turn-helix domain
IGHPPKDA_02194 1.8e-48
IGHPPKDA_02195 2.6e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGHPPKDA_02196 1.3e-110 XK27_02070 S Nitroreductase family
IGHPPKDA_02197 1.3e-69 rnhA 3.1.26.4 L Ribonuclease HI
IGHPPKDA_02198 1.3e-45 S Family of unknown function (DUF5322)
IGHPPKDA_02199 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IGHPPKDA_02200 4.3e-80 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IGHPPKDA_02201 1e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IGHPPKDA_02202 1.7e-96 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IGHPPKDA_02203 2.6e-236 pyrP F Permease
IGHPPKDA_02204 3.3e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IGHPPKDA_02205 2.5e-239 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IGHPPKDA_02206 3e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IGHPPKDA_02207 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IGHPPKDA_02208 2.4e-156 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IGHPPKDA_02209 9.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IGHPPKDA_02210 8.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IGHPPKDA_02211 1.8e-148 pta 2.3.1.19, 2.3.1.8 C Phosphate acetyl/butaryl transferase
IGHPPKDA_02212 1e-204 buk 2.7.2.7 C Acetokinase family
IGHPPKDA_02213 9.8e-261 lpdA 1.8.1.4 C 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
IGHPPKDA_02214 7.8e-188 bfmBAA 1.2.4.4 C Dehydrogenase E1 component
IGHPPKDA_02215 1.3e-182 bfmBAB 1.2.4.1, 1.2.4.4 C Transketolase, pyrimidine binding domain
IGHPPKDA_02216 5.6e-210 bfmBB 2.3.1.168, 2.3.1.61 C 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
IGHPPKDA_02217 2.4e-178 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IGHPPKDA_02218 3.4e-195 pfoS S Phosphotransferase system, EIIC
IGHPPKDA_02219 1.7e-51 S MazG-like family
IGHPPKDA_02220 0.0 FbpA K Fibronectin-binding protein
IGHPPKDA_02221 1.2e-160 degV S EDD domain protein, DegV family
IGHPPKDA_02222 2.6e-100 3.6.1.13 L Belongs to the Nudix hydrolase family
IGHPPKDA_02223 4.5e-112 I ABC-2 family transporter protein
IGHPPKDA_02224 8.9e-164 CcmA V ABC transporter
IGHPPKDA_02225 9.6e-65 K helix_turn_helix gluconate operon transcriptional repressor
IGHPPKDA_02226 1.1e-218 ysdA CP ABC-2 family transporter protein
IGHPPKDA_02227 7.4e-166 natA S abc transporter atp-binding protein
IGHPPKDA_02228 3.2e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IGHPPKDA_02229 1.9e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IGHPPKDA_02230 2.8e-160 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IGHPPKDA_02231 1.8e-203 S Calcineurin-like phosphoesterase
IGHPPKDA_02232 0.0 asnB 6.3.5.4 E Asparagine synthase
IGHPPKDA_02233 3.6e-69 FG Scavenger mRNA decapping enzyme C-term binding
IGHPPKDA_02234 1.5e-124 WQ51_05710 S Mitochondrial biogenesis AIM24
IGHPPKDA_02235 8.6e-130 mesE M Transport protein ComB
IGHPPKDA_02236 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IGHPPKDA_02239 9.8e-134 2.7.13.3 T protein histidine kinase activity
IGHPPKDA_02240 9.5e-144 plnD K LytTr DNA-binding domain
IGHPPKDA_02243 7.8e-11
IGHPPKDA_02247 3.6e-141 S CAAX protease self-immunity
IGHPPKDA_02249 6.8e-56
IGHPPKDA_02251 8.4e-54 S Enterocin A Immunity
IGHPPKDA_02252 7.7e-80 yncA 2.3.1.79 S Maltose acetyltransferase
IGHPPKDA_02261 4.3e-80 ctsR K Belongs to the CtsR family
IGHPPKDA_02262 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IGHPPKDA_02263 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGHPPKDA_02264 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGHPPKDA_02265 3.8e-31 3.4.23.43
IGHPPKDA_02266 7.9e-131 yhgE V domain protein
IGHPPKDA_02267 7.5e-46 S Thiamine-binding protein
IGHPPKDA_02268 1.2e-137 magIII L Base excision DNA repair protein, HhH-GPD family
IGHPPKDA_02269 3.3e-160 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
IGHPPKDA_02270 1.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IGHPPKDA_02271 7.1e-253 rarA L recombination factor protein RarA
IGHPPKDA_02272 1.2e-57
IGHPPKDA_02273 4.7e-177 yhaI S Protein of unknown function (DUF805)
IGHPPKDA_02274 5.4e-217 L Mga helix-turn-helix domain
IGHPPKDA_02275 2.2e-31 L Mga helix-turn-helix domain
IGHPPKDA_02277 7.6e-181 ynjC S Cell surface protein
IGHPPKDA_02278 4e-120 S WxL domain surface cell wall-binding
IGHPPKDA_02279 1.6e-22 3.1.1.32, 3.1.1.4 S COG0790 FOG TPR repeat, SEL1 subfamily
IGHPPKDA_02280 5.1e-44 mesE M Transport protein ComB
IGHPPKDA_02281 4.2e-08 S Protein of unknown function (DUF1093)
IGHPPKDA_02282 5.3e-18 S Bacterial mobilisation protein (MobC)
IGHPPKDA_02283 3e-52 D Relaxase/Mobilisation nuclease domain
IGHPPKDA_02286 7.4e-45 repB L Protein involved in initiation of plasmid replication
IGHPPKDA_02290 4.8e-66 S CAAX protease self-immunity
IGHPPKDA_02291 2.5e-276 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IGHPPKDA_02292 4.6e-52 prrC S AAA domain
IGHPPKDA_02293 2.6e-80 K Acetyltransferase (GNAT) domain
IGHPPKDA_02294 1.2e-91 yveA 3.5.1.19 Q Isochorismatase family
IGHPPKDA_02295 7.2e-55
IGHPPKDA_02297 2.4e-93 K Helix-turn-helix domain
IGHPPKDA_02298 1e-90 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IGHPPKDA_02299 4.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IGHPPKDA_02300 8.6e-254 ugpB G Bacterial extracellular solute-binding protein
IGHPPKDA_02301 3.4e-149 ugpE G ABC transporter permease
IGHPPKDA_02302 1.6e-163 ugpA P ABC-type sugar transport systems, permease components
IGHPPKDA_02303 2.7e-143 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
IGHPPKDA_02304 1.2e-129 E lipolytic protein G-D-S-L family
IGHPPKDA_02305 2.3e-114 epsB M biosynthesis protein
IGHPPKDA_02306 5.8e-103 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IGHPPKDA_02308 1.4e-46 cps1B GT2,GT4 M Glycosyl transferases group 1
IGHPPKDA_02309 7.3e-108 cps2I S Psort location CytoplasmicMembrane, score
IGHPPKDA_02310 1.3e-59 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
IGHPPKDA_02311 1.5e-24 GT2 M Glycosyltransferase like family 2
IGHPPKDA_02312 1.2e-53 wbbK M transferase activity, transferring glycosyl groups
IGHPPKDA_02313 2.3e-49 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
IGHPPKDA_02314 1.2e-143 IQ NAD dependent epimerase/dehydratase family
IGHPPKDA_02315 9.2e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IGHPPKDA_02316 9e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
IGHPPKDA_02317 5e-167 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
IGHPPKDA_02318 5.7e-138 repA K DeoR C terminal sensor domain
IGHPPKDA_02319 9.6e-115 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
IGHPPKDA_02320 9.7e-46 sgaB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_02321 3.5e-280 ulaA S PTS system sugar-specific permease component
IGHPPKDA_02322 5e-81 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IGHPPKDA_02323 1.9e-216 ulaG S Beta-lactamase superfamily domain
IGHPPKDA_02324 3.8e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IGHPPKDA_02326 7.4e-130 repA K DeoR C terminal sensor domain
IGHPPKDA_02327 2.9e-134 zmp3 O Zinc-dependent metalloprotease
IGHPPKDA_02328 2e-78 lytN 3.5.1.104 M LysM domain
IGHPPKDA_02329 1.5e-167 lytN 3.5.1.104 M LysM domain
IGHPPKDA_02330 2.3e-15 2.7.1.39 S Phosphotransferase enzyme family
IGHPPKDA_02331 3.2e-68 S Iron-sulphur cluster biosynthesis
IGHPPKDA_02333 6.2e-76
IGHPPKDA_02334 2.5e-230
IGHPPKDA_02335 1.5e-47 S Protein of unknown function (DUF2568)
IGHPPKDA_02336 1.5e-65 K helix_turn_helix, mercury resistance
IGHPPKDA_02337 3.7e-209
IGHPPKDA_02338 3.5e-123 yvfR V ABC transporter
IGHPPKDA_02339 1.3e-89 yvfS V ABC-2 type transporter
IGHPPKDA_02340 2.9e-151 desK 2.7.13.3 T Histidine kinase
IGHPPKDA_02341 3e-102 desR K helix_turn_helix, Lux Regulon
IGHPPKDA_02342 1.1e-153 S Uncharacterised protein, DegV family COG1307
IGHPPKDA_02346 2.2e-09
IGHPPKDA_02347 6.7e-223 L Belongs to the 'phage' integrase family
IGHPPKDA_02349 5.8e-28
IGHPPKDA_02350 1.3e-173 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IGHPPKDA_02351 8.1e-159 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IGHPPKDA_02352 7.5e-166 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IGHPPKDA_02353 6.5e-213 ydiN EGP Major Facilitator Superfamily
IGHPPKDA_02354 3.6e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IGHPPKDA_02355 1.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
IGHPPKDA_02356 1e-159 G Xylose isomerase-like TIM barrel
IGHPPKDA_02357 1.1e-164 K Transcriptional regulator, LysR family
IGHPPKDA_02358 2.8e-77 S Protein of unknown function (DUF1440)
IGHPPKDA_02359 7.8e-274 ycaM E amino acid
IGHPPKDA_02360 0.0 pepN 3.4.11.2 E aminopeptidase
IGHPPKDA_02361 0.0 O Belongs to the peptidase S8 family
IGHPPKDA_02362 0.0 O Belongs to the peptidase S8 family
IGHPPKDA_02363 3.9e-92
IGHPPKDA_02364 3.5e-208
IGHPPKDA_02365 7.7e-139 V ATPases associated with a variety of cellular activities
IGHPPKDA_02366 6.6e-196 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IGHPPKDA_02367 7.7e-126 K Transcriptional regulatory protein, C terminal
IGHPPKDA_02368 8.7e-298 S Psort location CytoplasmicMembrane, score
IGHPPKDA_02369 1.1e-127 XK27_12140 V ATPases associated with a variety of cellular activities
IGHPPKDA_02370 5.6e-200 3.4.22.70 M Sortase family
IGHPPKDA_02371 1.8e-184 M LPXTG cell wall anchor motif
IGHPPKDA_02372 2.5e-124 M domain protein
IGHPPKDA_02373 0.0 yvcC M Cna protein B-type domain
IGHPPKDA_02374 7e-104 L Resolvase, N terminal domain
IGHPPKDA_02375 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
IGHPPKDA_02376 1.5e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_02377 1.1e-226 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGHPPKDA_02378 3.4e-56 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IGHPPKDA_02379 4.8e-292 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IGHPPKDA_02380 3.2e-96
IGHPPKDA_02381 8.4e-57 hxlR K HxlR-like helix-turn-helix
IGHPPKDA_02382 4.1e-200 qor 1.1.1.1, 1.6.5.5 C Zinc-binding dehydrogenase
IGHPPKDA_02383 1.7e-162 morA2 S reductase
IGHPPKDA_02384 1.9e-74 K helix_turn_helix, mercury resistance
IGHPPKDA_02385 1.3e-246 E Amino acid permease
IGHPPKDA_02386 4.6e-221 S Amidohydrolase
IGHPPKDA_02387 9e-256 6.3.1.2 E Glutamine synthetase, catalytic domain
IGHPPKDA_02388 3.7e-142 puuD S peptidase C26
IGHPPKDA_02389 9.7e-143 H Protein of unknown function (DUF1698)
IGHPPKDA_02390 3.1e-150 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IGHPPKDA_02391 2.3e-131 V Beta-lactamase
IGHPPKDA_02392 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IGHPPKDA_02393 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IGHPPKDA_02394 5.6e-106 tag 3.2.2.20 L glycosylase
IGHPPKDA_02395 1e-105 K Transcriptional
IGHPPKDA_02396 1e-202 yceJ EGP Major facilitator Superfamily
IGHPPKDA_02397 3.9e-47 K Helix-turn-helix domain
IGHPPKDA_02398 7.2e-264 L Exonuclease
IGHPPKDA_02399 6e-52
IGHPPKDA_02400 1.5e-76 ohr O OsmC-like protein
IGHPPKDA_02401 1.4e-189 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IGHPPKDA_02402 1e-102 dhaL 2.7.1.121 S Dak2
IGHPPKDA_02403 7.3e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
IGHPPKDA_02404 1.5e-100 K Bacterial regulatory proteins, tetR family
IGHPPKDA_02405 1.7e-15
IGHPPKDA_02406 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
IGHPPKDA_02407 7.9e-84
IGHPPKDA_02408 2.5e-197 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IGHPPKDA_02409 1.7e-154 metQ_4 P Belongs to the nlpA lipoprotein family
IGHPPKDA_02410 0.0 pip V domain protein
IGHPPKDA_02412 3e-304 yfiB V ABC transporter transmembrane region
IGHPPKDA_02413 3.2e-193 md2 V ABC transporter
IGHPPKDA_02415 1.2e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IGHPPKDA_02416 1.2e-196 cpoA GT4 M Glycosyltransferase, group 1 family protein
IGHPPKDA_02417 1.9e-165 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IGHPPKDA_02419 7.7e-219 patA 2.6.1.1 E Aminotransferase
IGHPPKDA_02420 1.9e-43 ykuJ S Protein of unknown function (DUF1797)
IGHPPKDA_02421 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IGHPPKDA_02422 4e-80 perR P Belongs to the Fur family
IGHPPKDA_02423 2.2e-15 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IGHPPKDA_02424 2.4e-184 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IGHPPKDA_02425 5.8e-137 S Domain of unknown function (DUF4918)
IGHPPKDA_02426 5.2e-204
IGHPPKDA_02427 1e-07
IGHPPKDA_02429 5.1e-302 norB EGP Major Facilitator
IGHPPKDA_02430 2.5e-106 K Bacterial regulatory proteins, tetR family
IGHPPKDA_02432 1.4e-122
IGHPPKDA_02434 1.7e-219 ybfG M peptidoglycan-binding domain-containing protein
IGHPPKDA_02438 8.7e-78 repB L Protein involved in initiation of plasmid replication
IGHPPKDA_02441 0.0 ydaO E amino acid
IGHPPKDA_02442 3.2e-56 S Domain of unknown function (DUF1827)
IGHPPKDA_02443 1e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IGHPPKDA_02444 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IGHPPKDA_02445 4.2e-110 S CAAX protease self-immunity
IGHPPKDA_02446 2.2e-193 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IGHPPKDA_02447 1.1e-32
IGHPPKDA_02449 3.2e-155 dnaC L IstB-like ATP binding protein
IGHPPKDA_02450 7.7e-140 L Helix-turn-helix domain
IGHPPKDA_02456 7.8e-44 S Domain of unknown function (DUF1883)
IGHPPKDA_02458 1e-136 S ORF6N domain
IGHPPKDA_02459 1e-156 ps305 S Protein of unknown function (Hypoth_ymh)
IGHPPKDA_02462 7.5e-61 ps115 K Helix-turn-helix XRE-family like proteins
IGHPPKDA_02463 6e-20 E Zn peptidase
IGHPPKDA_02464 1.3e-120
IGHPPKDA_02465 4.9e-21 M Cna B domain protein
IGHPPKDA_02467 2.6e-85 repA S Replication initiator protein A
IGHPPKDA_02468 6.5e-84 D CobQ CobB MinD ParA nucleotide binding domain protein
IGHPPKDA_02470 9.8e-09
IGHPPKDA_02472 8.8e-305 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
IGHPPKDA_02474 1.4e-304 3.6.3.3, 3.6.3.5 P P-type ATPase
IGHPPKDA_02475 5.6e-33 copZ P Heavy-metal-associated domain
IGHPPKDA_02476 2.6e-98 dps P Belongs to the Dps family
IGHPPKDA_02477 4.4e-115 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
IGHPPKDA_02478 2e-138 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IGHPPKDA_02479 3.6e-227 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IGHPPKDA_02480 2.3e-102 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IGHPPKDA_02481 9.1e-110 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IGHPPKDA_02482 3.2e-16
IGHPPKDA_02485 7.4e-77 repB L Initiator Replication protein
IGHPPKDA_02486 6.1e-30
IGHPPKDA_02488 1.6e-07
IGHPPKDA_02490 5.9e-17 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
IGHPPKDA_02491 0.0 S Protein of unknown function (DUF1524)
IGHPPKDA_02492 4.1e-153 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
IGHPPKDA_02493 2.4e-145 cylB V ABC-2 type transporter
IGHPPKDA_02494 5.6e-30
IGHPPKDA_02495 7.5e-65 nrp 1.20.4.1 P ArsC family
IGHPPKDA_02496 0.0 fbp 3.1.3.11 G phosphatase activity
IGHPPKDA_02497 1.4e-145 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IGHPPKDA_02498 2.2e-101 ylcC 3.4.22.70 M Sortase family
IGHPPKDA_02499 4.7e-204 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IGHPPKDA_02500 0.0 typA T GTP-binding protein TypA
IGHPPKDA_02501 1.3e-145 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IGHPPKDA_02502 2.4e-46 yktA S Belongs to the UPF0223 family
IGHPPKDA_02503 5.4e-156 1.1.1.27 C L-malate dehydrogenase activity
IGHPPKDA_02504 2.4e-259 lpdA 1.8.1.4 C Dehydrogenase
IGHPPKDA_02505 2.5e-268 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IGHPPKDA_02506 6.2e-182 pdhB 1.2.4.1, 1.2.4.4 C Transketolase, C-terminal domain protein
IGHPPKDA_02507 1.5e-211 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IGHPPKDA_02508 5.2e-89 S E1-E2 ATPase
IGHPPKDA_02509 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IGHPPKDA_02510 3.3e-46
IGHPPKDA_02511 4.7e-68
IGHPPKDA_02512 2.9e-31 ykzG S Belongs to the UPF0356 family
IGHPPKDA_02513 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IGHPPKDA_02514 1.6e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IGHPPKDA_02515 4.2e-244 els S Sterol carrier protein domain
IGHPPKDA_02516 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IGHPPKDA_02517 1.8e-116 S Repeat protein
IGHPPKDA_02518 9.9e-123 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IGHPPKDA_02519 9.9e-241 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IGHPPKDA_02520 0.0 uvrA2 L ABC transporter
IGHPPKDA_02521 2.9e-57 XK27_04120 S Putative amino acid metabolism
IGHPPKDA_02522 1.3e-218 iscS 2.8.1.7 E Aminotransferase class V
IGHPPKDA_02523 4.8e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IGHPPKDA_02524 2.1e-28
IGHPPKDA_02525 4.6e-94 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IGHPPKDA_02526 2e-115 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IGHPPKDA_02527 1.8e-210 yaaN P Toxic anion resistance protein (TelA)
IGHPPKDA_02528 9.6e-264 ydiC1 EGP Major facilitator Superfamily
IGHPPKDA_02529 2.5e-153 pstS P Phosphate
IGHPPKDA_02530 1.5e-35 cspA K Cold shock protein
IGHPPKDA_02531 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IGHPPKDA_02532 8.8e-86 divIVA D DivIVA protein
IGHPPKDA_02533 2.9e-145 ylmH S S4 domain protein
IGHPPKDA_02534 2.4e-44 yggT S integral membrane protein
IGHPPKDA_02535 8.7e-78 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IGHPPKDA_02536 5.9e-225 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IGHPPKDA_02537 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IGHPPKDA_02538 1.5e-155 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IGHPPKDA_02539 1.8e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IGHPPKDA_02540 9.2e-264 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IGHPPKDA_02541 2.2e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IGHPPKDA_02542 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IGHPPKDA_02543 3.1e-49 ftsL D cell division protein FtsL
IGHPPKDA_02544 1.1e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IGHPPKDA_02545 9.8e-79 mraZ K Belongs to the MraZ family
IGHPPKDA_02546 4.2e-45
IGHPPKDA_02547 1.4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGHPPKDA_02548 2.8e-151 aatB ET ABC transporter substrate-binding protein
IGHPPKDA_02549 6.9e-113 glnQ 3.6.3.21 E ABC transporter
IGHPPKDA_02550 1.2e-109 artQ P ABC transporter permease
IGHPPKDA_02551 2.6e-141 minD D Belongs to the ParA family
IGHPPKDA_02552 4.4e-115 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IGHPPKDA_02553 2.3e-85 mreD M rod shape-determining protein MreD
IGHPPKDA_02554 3.6e-149 mreC M Involved in formation and maintenance of cell shape
IGHPPKDA_02555 1e-179 mreB D cell shape determining protein MreB
IGHPPKDA_02556 9.7e-118 radC L DNA repair protein
IGHPPKDA_02557 1.3e-114 S Haloacid dehalogenase-like hydrolase
IGHPPKDA_02558 3.8e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IGHPPKDA_02559 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IGHPPKDA_02560 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IGHPPKDA_02561 4.3e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IGHPPKDA_02562 3.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
IGHPPKDA_02563 2.1e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IGHPPKDA_02564 4.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
IGHPPKDA_02565 6.1e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IGHPPKDA_02567 3.5e-129
IGHPPKDA_02568 6.5e-54
IGHPPKDA_02569 0.0 yhgF K Tex-like protein N-terminal domain protein
IGHPPKDA_02571 2.6e-46 S Bacterial toxin of type II toxin-antitoxin system, YafQ
IGHPPKDA_02572 3.5e-42 L RelB antitoxin
IGHPPKDA_02573 4.1e-121 K Acetyltransferase (GNAT) domain
IGHPPKDA_02574 1.1e-128 S Protein of unknown function C-terminus (DUF2399)
IGHPPKDA_02575 1.3e-299 D Putative exonuclease SbcCD, C subunit
IGHPPKDA_02576 2e-51 capM M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IGHPPKDA_02577 1.5e-132 pglC M Bacterial sugar transferase
IGHPPKDA_02578 9.1e-163 fnlA 4.2.1.115, 5.1.3.2 M Polysaccharide biosynthesis protein
IGHPPKDA_02579 1.2e-153 capF 1.1.1.367 GM NAD dependent epimerase/dehydratase family
IGHPPKDA_02580 8.8e-175 wecB 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
IGHPPKDA_02581 8e-74 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IGHPPKDA_02582 1e-215 hsdM 2.1.1.72 V type I restriction-modification system
IGHPPKDA_02583 3.3e-103 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
IGHPPKDA_02584 1.8e-23
IGHPPKDA_02585 4.6e-249 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
IGHPPKDA_02586 3.1e-53
IGHPPKDA_02587 9.4e-65
IGHPPKDA_02588 3.2e-170 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGHPPKDA_02589 4e-82 L Psort location Cytoplasmic, score
IGHPPKDA_02590 5.6e-52 L 4.5 Transposon and IS
IGHPPKDA_02592 5.8e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IGHPPKDA_02593 8.6e-163 K Transcriptional regulator
IGHPPKDA_02594 2.2e-279 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IGHPPKDA_02595 3.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IGHPPKDA_02596 2.8e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IGHPPKDA_02597 8.4e-15 yncA 2.3.1.79 S Maltose acetyltransferase
IGHPPKDA_02599 1.1e-12 doc S Prophage maintenance system killer protein
IGHPPKDA_02600 2e-180 S Aldo keto reductase
IGHPPKDA_02601 5.1e-120 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IGHPPKDA_02602 3.5e-216 yqiG C Oxidoreductase
IGHPPKDA_02603 2.1e-252 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IGHPPKDA_02604 4.2e-133
IGHPPKDA_02605 1.2e-198 GKT transcriptional antiterminator
IGHPPKDA_02606 1.5e-49 ptxB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_02607 9.3e-210 ulaA 2.7.1.194 S PTS system sugar-specific permease component
IGHPPKDA_02608 5.6e-71
IGHPPKDA_02609 7.5e-163 4.1.2.13 G Fructose-bisphosphate aldolase class-II
IGHPPKDA_02610 4.3e-115 6.3.4.4 S Zeta toxin
IGHPPKDA_02611 2.7e-26 S Domain of unknown function (DUF4312)
IGHPPKDA_02612 6.9e-62 S Glycine-rich SFCGS
IGHPPKDA_02613 3.6e-55 S PRD domain
IGHPPKDA_02614 0.0 K Mga helix-turn-helix domain
IGHPPKDA_02615 9.1e-124 tal 2.2.1.2 H Pfam:Transaldolase
IGHPPKDA_02616 3.9e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IGHPPKDA_02617 1.2e-205 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
IGHPPKDA_02618 6.3e-102 srlA G PTS system enzyme II sorbitol-specific factor
IGHPPKDA_02619 2.5e-102 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IGHPPKDA_02620 3.6e-22 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IGHPPKDA_02621 1.1e-144 ywqE 3.1.3.48 GM PHP domain protein
IGHPPKDA_02622 1.3e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IGHPPKDA_02623 6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IGHPPKDA_02624 3.9e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IGHPPKDA_02625 5.2e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IGHPPKDA_02626 5.4e-156 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IGHPPKDA_02627 6.3e-138
IGHPPKDA_02628 6.4e-45 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_02629 2.4e-65 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IGHPPKDA_02630 5.5e-237 gatC G PTS system sugar-specific permease component
IGHPPKDA_02631 8.8e-142 IQ KR domain
IGHPPKDA_02632 1.6e-139 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 F pfkB family carbohydrate kinase
IGHPPKDA_02633 1.5e-13 XK27_08465 2.7.1.191 G PTS system fructose IIA component
IGHPPKDA_02634 2.5e-26 XK27_08465 2.7.1.191 G PTS system fructose IIA component
IGHPPKDA_02635 4.7e-48 L Transposase and inactivated derivatives, IS30 family
IGHPPKDA_02636 1.2e-97 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
IGHPPKDA_02637 1.3e-162 ptlF S KR domain
IGHPPKDA_02638 2.9e-166 QT PucR C-terminal helix-turn-helix domain
IGHPPKDA_02639 1.4e-92 QT PucR C-terminal helix-turn-helix domain
IGHPPKDA_02640 3.1e-68 yqkB S Belongs to the HesB IscA family
IGHPPKDA_02641 2.7e-241 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
IGHPPKDA_02642 5.3e-124 K cheY-homologous receiver domain
IGHPPKDA_02643 6.4e-66 L transposition
IGHPPKDA_02645 5.3e-48 repB L Protein involved in initiation of plasmid replication
IGHPPKDA_02646 3.6e-11
IGHPPKDA_02647 3e-45 sugE P Multidrug Resistance protein
IGHPPKDA_02648 4.7e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IGHPPKDA_02649 8.7e-177 pfoS S Phosphotransferase system, EIIC
IGHPPKDA_02650 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IGHPPKDA_02651 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IGHPPKDA_02652 5.5e-242 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IGHPPKDA_02653 9.3e-70 yabR J RNA binding
IGHPPKDA_02654 1.1e-66 divIC D cell cycle
IGHPPKDA_02655 2.7e-39 yabO J S4 domain protein
IGHPPKDA_02656 1e-279 yabM S Polysaccharide biosynthesis protein
IGHPPKDA_02657 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IGHPPKDA_02658 3.6e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IGHPPKDA_02659 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IGHPPKDA_02660 1.5e-261 S Putative peptidoglycan binding domain
IGHPPKDA_02661 2.3e-119 S (CBS) domain
IGHPPKDA_02662 4e-122 yciB M ErfK YbiS YcfS YnhG
IGHPPKDA_02663 2.9e-284 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IGHPPKDA_02664 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
IGHPPKDA_02665 4.5e-86 S QueT transporter
IGHPPKDA_02666 5.6e-62 ndoA L Toxic component of a toxin-antitoxin (TA) module
IGHPPKDA_02667 5.2e-32
IGHPPKDA_02668 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IGHPPKDA_02669 8.5e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IGHPPKDA_02670 7e-265 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IGHPPKDA_02672 1.9e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IGHPPKDA_02673 1.1e-144
IGHPPKDA_02674 3.2e-08
IGHPPKDA_02675 1.4e-121 S Tetratricopeptide repeat
IGHPPKDA_02676 3.7e-125
IGHPPKDA_02677 1.2e-65
IGHPPKDA_02678 2.5e-42 rpmE2 J Ribosomal protein L31
IGHPPKDA_02679 1.6e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IGHPPKDA_02680 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IGHPPKDA_02681 2.8e-157 S Protein of unknown function (DUF1211)
IGHPPKDA_02682 4.5e-54 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IGHPPKDA_02683 5e-78 ywiB S Domain of unknown function (DUF1934)
IGHPPKDA_02684 4.3e-155 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
IGHPPKDA_02685 3.5e-268 ywfO S HD domain protein
IGHPPKDA_02686 1.4e-80 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
IGHPPKDA_02687 1.1e-179 S DUF218 domain
IGHPPKDA_02688 2.1e-53 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IGHPPKDA_02689 3e-79 E glutamate:sodium symporter activity
IGHPPKDA_02690 6.5e-54 nudA S ASCH
IGHPPKDA_02691 1.3e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IGHPPKDA_02692 2.2e-217 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IGHPPKDA_02693 9.4e-175 ysaA V RDD family
IGHPPKDA_02694 1e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IGHPPKDA_02695 7.7e-120 ybbL S ABC transporter, ATP-binding protein
IGHPPKDA_02696 9e-120 ybbM S Uncharacterised protein family (UPF0014)
IGHPPKDA_02697 1.3e-159 czcD P cation diffusion facilitator family transporter
IGHPPKDA_02698 2e-180 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IGHPPKDA_02699 1.1e-37 veg S Biofilm formation stimulator VEG
IGHPPKDA_02700 2.6e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IGHPPKDA_02701 1.3e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IGHPPKDA_02702 1.8e-147 tatD L hydrolase, TatD family
IGHPPKDA_02703 1.7e-79 manR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphoenolpyruvate-dependent sugar phosphotransferase system
IGHPPKDA_02704 2.5e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
IGHPPKDA_02705 5.3e-172 yqhA G Aldose 1-epimerase
IGHPPKDA_02706 3.4e-121 T LytTr DNA-binding domain
IGHPPKDA_02707 2.5e-124 2.7.13.3 T GHKL domain
IGHPPKDA_02708 0.0 V ABC transporter
IGHPPKDA_02709 0.0 V ABC transporter
IGHPPKDA_02710 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IGHPPKDA_02711 4.3e-174 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
IGHPPKDA_02712 8.6e-153 yunF F Protein of unknown function DUF72
IGHPPKDA_02713 1.9e-91 3.6.1.55 F NUDIX domain
IGHPPKDA_02714 6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IGHPPKDA_02715 1.7e-105 yiiE S Protein of unknown function (DUF1211)
IGHPPKDA_02716 2.8e-128 cobB K Sir2 family
IGHPPKDA_02717 1.4e-16
IGHPPKDA_02718 2.3e-170
IGHPPKDA_02720 2e-94 yxkA S Phosphatidylethanolamine-binding protein
IGHPPKDA_02721 1.6e-18
IGHPPKDA_02722 2.8e-150 ypuA S Protein of unknown function (DUF1002)
IGHPPKDA_02723 2.7e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IGHPPKDA_02724 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IGHPPKDA_02725 6.1e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IGHPPKDA_02726 9.2e-175 S Aldo keto reductase
IGHPPKDA_02727 5.1e-153 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
IGHPPKDA_02728 6.8e-92 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IGHPPKDA_02729 1.1e-116 S Bacterial protein of unknown function (DUF916)
IGHPPKDA_02730 4.3e-161 S WxL domain surface cell wall-binding
IGHPPKDA_02731 5.9e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IGHPPKDA_02732 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IGHPPKDA_02733 6.6e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IGHPPKDA_02735 1.4e-49 S Protein of unknown function (DUF1093)
IGHPPKDA_02736 4.9e-30 G PTS system fructose IIA component
IGHPPKDA_02737 2e-117 G PTS system mannose/fructose/sorbose family IID component
IGHPPKDA_02738 7.3e-120 agaC G PTS system sorbose-specific iic component
IGHPPKDA_02739 4e-65 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
IGHPPKDA_02740 8e-41 K UTRA domain
IGHPPKDA_02741 3.8e-41 soj D CobQ CobB MinD ParA nucleotide binding domain protein
IGHPPKDA_02743 1.9e-22
IGHPPKDA_02744 1.1e-170 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
IGHPPKDA_02745 1.4e-23
IGHPPKDA_02746 4.4e-20
IGHPPKDA_02748 5.7e-263 yhgE V domain protein
IGHPPKDA_02749 7e-101 yobS K Bacterial regulatory proteins, tetR family
IGHPPKDA_02750 6.8e-131 S Sulfite exporter TauE/SafE
IGHPPKDA_02751 1.1e-178 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
IGHPPKDA_02752 2.3e-98 3.1.1.24 S Alpha/beta hydrolase family
IGHPPKDA_02755 2.3e-20 ps301 K Protein of unknown function (DUF4065)
IGHPPKDA_02756 1.3e-193 L Transposase DDE domain
IGHPPKDA_02757 3.5e-39 L Transposase DDE domain
IGHPPKDA_02758 1.6e-80 ccl S QueT transporter
IGHPPKDA_02759 1.9e-124 IQ Enoyl-(Acyl carrier protein) reductase
IGHPPKDA_02760 1.1e-36 XK27_01315 S Protein of unknown function (DUF2829)
IGHPPKDA_02761 5.4e-47 K sequence-specific DNA binding
IGHPPKDA_02763 1.7e-58 S Initiator Replication protein
IGHPPKDA_02766 2.3e-25 L Initiator Replication protein
IGHPPKDA_02768 1.3e-48 repA S Replication initiator protein A
IGHPPKDA_02769 3.9e-44 relB L Addiction module antitoxin, RelB DinJ family
IGHPPKDA_02770 1.1e-86
IGHPPKDA_02771 3.1e-41
IGHPPKDA_02772 7.2e-27
IGHPPKDA_02773 1.5e-136 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
IGHPPKDA_02774 2.2e-20
IGHPPKDA_02775 3e-17 S Family of unknown function (DUF5388)
IGHPPKDA_02776 2e-93 D CobQ CobB MinD ParA nucleotide binding domain protein
IGHPPKDA_02777 3.9e-11 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IGHPPKDA_02779 6.3e-73
IGHPPKDA_02781 1.8e-67
IGHPPKDA_02782 3e-16
IGHPPKDA_02783 1.2e-64
IGHPPKDA_02784 1.7e-129
IGHPPKDA_02785 4.8e-157 ytrB V ABC transporter
IGHPPKDA_02786 1e-60 ytrA K helix_turn_helix gluconate operon transcriptional repressor
IGHPPKDA_02787 7.2e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IGHPPKDA_02788 0.0 uup S ABC transporter, ATP-binding protein
IGHPPKDA_02789 3.9e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IGHPPKDA_02790 4.2e-189 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IGHPPKDA_02791 2.1e-99 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IGHPPKDA_02792 1.2e-129 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IGHPPKDA_02793 6e-74
IGHPPKDA_02794 3.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
IGHPPKDA_02795 2e-180 ansA 3.5.1.1 EJ Asparaginase
IGHPPKDA_02796 3.9e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
IGHPPKDA_02797 4.5e-144 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IGHPPKDA_02798 2.2e-57 yabA L Involved in initiation control of chromosome replication
IGHPPKDA_02799 5.3e-173 holB 2.7.7.7 L DNA polymerase III
IGHPPKDA_02800 4.6e-52 yaaQ S Cyclic-di-AMP receptor
IGHPPKDA_02801 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IGHPPKDA_02802 5.8e-34 S Protein of unknown function (DUF2508)
IGHPPKDA_02803 1.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IGHPPKDA_02804 8.4e-32 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IGHPPKDA_02805 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IGHPPKDA_02806 1.9e-89 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IGHPPKDA_02807 5.6e-50
IGHPPKDA_02808 7.6e-106 rsmC 2.1.1.172 J Methyltransferase
IGHPPKDA_02809 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IGHPPKDA_02810 1.8e-45
IGHPPKDA_02811 2.2e-176 ccpB 5.1.1.1 K lacI family
IGHPPKDA_02812 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
IGHPPKDA_02813 2.4e-156 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IGHPPKDA_02814 1.1e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IGHPPKDA_02815 6.5e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IGHPPKDA_02816 3e-221 mdtG EGP Major facilitator Superfamily
IGHPPKDA_02817 5.1e-148 K acetyltransferase
IGHPPKDA_02818 4.7e-67
IGHPPKDA_02819 1.5e-217 yceI G Sugar (and other) transporter
IGHPPKDA_02820 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IGHPPKDA_02821 1.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IGHPPKDA_02822 8.2e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IGHPPKDA_02823 0.0 mgtA 3.6.3.2, 3.6.3.6 P COG0474 Cation transport ATPase
IGHPPKDA_02824 1.7e-268 nylA 3.5.1.4 J Belongs to the amidase family
IGHPPKDA_02825 8.1e-66 frataxin S Domain of unknown function (DU1801)
IGHPPKDA_02826 6.2e-91 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
IGHPPKDA_02827 1.2e-95 S ECF transporter, substrate-specific component
IGHPPKDA_02828 5.1e-63 S Domain of unknown function (DUF4430)
IGHPPKDA_02829 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
IGHPPKDA_02830 5e-78 F Nucleoside 2-deoxyribosyltransferase
IGHPPKDA_02831 8.4e-159 S Alpha/beta hydrolase of unknown function (DUF915)
IGHPPKDA_02832 3.4e-100 nusG K Participates in transcription elongation, termination and antitermination
IGHPPKDA_02833 5.7e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IGHPPKDA_02834 5.5e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IGHPPKDA_02835 5.7e-172 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IGHPPKDA_02836 4.5e-169 menA 2.5.1.74 M UbiA prenyltransferase family
IGHPPKDA_02837 1.5e-197 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IGHPPKDA_02838 2.6e-137 cad S FMN_bind
IGHPPKDA_02839 0.0 ndh 1.6.99.3 C NADH dehydrogenase
IGHPPKDA_02840 3.1e-80 ynhH S NusG domain II
IGHPPKDA_02841 2.6e-98 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
IGHPPKDA_02842 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IGHPPKDA_02845 6e-123 1.5.1.40 S Rossmann-like domain
IGHPPKDA_02846 8.2e-188 XK27_00915 C Luciferase-like monooxygenase
IGHPPKDA_02848 2.4e-98 yacP S YacP-like NYN domain
IGHPPKDA_02849 3.3e-141 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGHPPKDA_02850 8.5e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IGHPPKDA_02851 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IGHPPKDA_02852 1.5e-261 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
IGHPPKDA_02853 2.6e-106
IGHPPKDA_02855 6.2e-274 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IGHPPKDA_02856 9.3e-186 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
IGHPPKDA_02857 1.4e-116 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
IGHPPKDA_02858 2.7e-141 K SIS domain
IGHPPKDA_02859 8.2e-114 yhfC S Putative membrane peptidase family (DUF2324)
IGHPPKDA_02860 4.1e-176 S Membrane
IGHPPKDA_02861 2.7e-61 K helix_turn_helix gluconate operon transcriptional repressor
IGHPPKDA_02862 4.1e-218 inlJ M MucBP domain
IGHPPKDA_02863 4.8e-17 S ABC-2 family transporter protein
IGHPPKDA_02864 1e-26 S ABC-2 family transporter protein
IGHPPKDA_02865 5.4e-267 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IGHPPKDA_02866 6.4e-107 pncA Q Isochorismatase family
IGHPPKDA_02867 1.5e-135 3.6.1.13, 3.6.1.55 F NUDIX domain
IGHPPKDA_02868 0.0 clpL O associated with various cellular activities
IGHPPKDA_02869 5e-78 ywqE 3.1.3.48 GM PHP domain protein
IGHPPKDA_02870 7.9e-24 L Replication initiation factor
IGHPPKDA_02872 7.9e-38 D plasmid recombination enzyme
IGHPPKDA_02875 4.6e-34
IGHPPKDA_02876 2.4e-57 O Torsin
IGHPPKDA_02877 9.3e-70 yqeB S Pyrimidine dimer DNA glycosylase
IGHPPKDA_02878 1.7e-69 pdxH S Pyridoxamine 5'-phosphate oxidase
IGHPPKDA_02880 1.9e-24
IGHPPKDA_02881 2.6e-40
IGHPPKDA_02882 6.5e-85 S protein conserved in bacteria
IGHPPKDA_02883 2.1e-28
IGHPPKDA_02884 0.0 copB 3.6.3.4 P P-type ATPase
IGHPPKDA_02885 1e-38 mdt(A) EGP Major facilitator Superfamily
IGHPPKDA_02886 6.4e-69 S COG NOG38524 non supervised orthologous group
IGHPPKDA_02887 4e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
IGHPPKDA_02888 9.8e-100 G Domain of unknown function (DUF4432)
IGHPPKDA_02889 5.8e-134 5.3.1.15 S Pfam:DUF1498
IGHPPKDA_02890 3.2e-283 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IGHPPKDA_02891 2.3e-269 ybeC E amino acid
IGHPPKDA_02892 6.1e-94 sigH K DNA-templated transcription, initiation
IGHPPKDA_02893 4.4e-132 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IGHPPKDA_02894 4.9e-81 ndk 2.7.4.6 F Belongs to the NDK family
IGHPPKDA_02895 0.0 yfgQ P E1-E2 ATPase
IGHPPKDA_02896 1.2e-179 3.4.11.5 I carboxylic ester hydrolase activity
IGHPPKDA_02897 2.6e-45
IGHPPKDA_02898 2.6e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IGHPPKDA_02899 4e-196 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IGHPPKDA_02900 2.2e-122 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
IGHPPKDA_02901 3.3e-77 K Transcriptional regulator
IGHPPKDA_02902 5.2e-178 D Alpha beta
IGHPPKDA_02903 2.5e-83 nrdI F Belongs to the NrdI family
IGHPPKDA_02904 1.3e-156 dkgB S reductase
IGHPPKDA_02905 1.7e-155
IGHPPKDA_02906 5.8e-144 S Alpha beta hydrolase
IGHPPKDA_02907 6.6e-119 yviA S Protein of unknown function (DUF421)
IGHPPKDA_02908 3.5e-74 S Protein of unknown function (DUF3290)
IGHPPKDA_02910 7.9e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
IGHPPKDA_02911 2.8e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IGHPPKDA_02912 4.2e-32 yjbF S SNARE associated Golgi protein
IGHPPKDA_02913 6e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IGHPPKDA_02914 3.2e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IGHPPKDA_02915 2.1e-207 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IGHPPKDA_02916 2.3e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IGHPPKDA_02917 1.2e-65 yajC U Preprotein translocase
IGHPPKDA_02918 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IGHPPKDA_02919 2.3e-116 sirR K Helix-turn-helix diphteria tox regulatory element
IGHPPKDA_02920 3.3e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IGHPPKDA_02921 2.7e-205 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IGHPPKDA_02922 2.3e-240 ytoI K DRTGG domain
IGHPPKDA_02923 3.7e-179 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IGHPPKDA_02924 4.3e-250 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IGHPPKDA_02925 7.8e-174
IGHPPKDA_02926 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IGHPPKDA_02928 4e-43 yrzL S Belongs to the UPF0297 family
IGHPPKDA_02929 1.6e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IGHPPKDA_02930 6.8e-53 yrzB S Belongs to the UPF0473 family
IGHPPKDA_02931 5.8e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IGHPPKDA_02932 9.5e-92 cvpA S Colicin V production protein
IGHPPKDA_02933 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IGHPPKDA_02934 6.6e-53 trxA O Belongs to the thioredoxin family
IGHPPKDA_02935 6.1e-20 dltX S D-Ala-teichoic acid biosynthesis protein
IGHPPKDA_02936 1.1e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGHPPKDA_02937 2.6e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
IGHPPKDA_02938 1.2e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGHPPKDA_02939 1.5e-244 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IGHPPKDA_02940 6.1e-85 yslB S Protein of unknown function (DUF2507)
IGHPPKDA_02941 3.8e-276 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IGHPPKDA_02942 2.5e-97 S Phosphoesterase
IGHPPKDA_02943 2.5e-135 gla U Major intrinsic protein
IGHPPKDA_02944 2.1e-85 ykuL S CBS domain
IGHPPKDA_02945 3.5e-155 XK27_00890 S Domain of unknown function (DUF368)
IGHPPKDA_02946 2.5e-153 ykuT M mechanosensitive ion channel
IGHPPKDA_02947 6e-12 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IGHPPKDA_02948 2.7e-86 ytxH S YtxH-like protein
IGHPPKDA_02949 1e-90 niaR S 3H domain
IGHPPKDA_02950 2.8e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IGHPPKDA_02951 5.1e-179 ccpA K catabolite control protein A
IGHPPKDA_02952 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
IGHPPKDA_02953 1.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
IGHPPKDA_02954 9.5e-138 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IGHPPKDA_02955 3.8e-273 pepV 3.5.1.18 E dipeptidase PepV
IGHPPKDA_02956 1.1e-258 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IGHPPKDA_02957 2.7e-54
IGHPPKDA_02958 7.5e-189 yibE S overlaps another CDS with the same product name
IGHPPKDA_02959 1.4e-114 yibF S overlaps another CDS with the same product name
IGHPPKDA_02960 1.8e-115 S Calcineurin-like phosphoesterase
IGHPPKDA_02961 9.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IGHPPKDA_02962 6e-117 yutD S Protein of unknown function (DUF1027)
IGHPPKDA_02963 2.8e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IGHPPKDA_02964 1.1e-112 S Protein of unknown function (DUF1461)
IGHPPKDA_02965 5.2e-116 dedA S SNARE-like domain protein
IGHPPKDA_02966 6.7e-87 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
IGHPPKDA_02967 7.9e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IGHPPKDA_02968 2.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IGHPPKDA_02969 1.1e-62 yugI 5.3.1.9 J general stress protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)