ORF_ID e_value Gene_name EC_number CAZy COGs Description
NDMLAEPG_00001 1.9e-221 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NDMLAEPG_00002 7.3e-246 yhcA V ABC transporter, ATP-binding protein
NDMLAEPG_00003 5.8e-35 K Bacterial regulatory proteins, tetR family
NDMLAEPG_00004 4.6e-37 lmrA V ABC transporter, ATP-binding protein
NDMLAEPG_00005 1.6e-172 lmrA V ABC transporter, ATP-binding protein
NDMLAEPG_00006 3.3e-253 yfiC V ABC transporter
NDMLAEPG_00008 3.2e-45 yjcF K protein acetylation
NDMLAEPG_00009 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
NDMLAEPG_00010 1.5e-71 lemA S LemA family
NDMLAEPG_00011 1.3e-114 htpX O Belongs to the peptidase M48B family
NDMLAEPG_00013 2.3e-272 helD 3.6.4.12 L DNA helicase
NDMLAEPG_00014 3.7e-32 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NDMLAEPG_00015 1.4e-90 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NDMLAEPG_00016 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NDMLAEPG_00017 9.4e-103 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NDMLAEPG_00018 8.4e-83 ybhF_2 V abc transporter atp-binding protein
NDMLAEPG_00019 3.5e-104 ybhR V ABC transporter
NDMLAEPG_00020 5.1e-31 K Transcriptional regulator
NDMLAEPG_00021 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
NDMLAEPG_00022 2.1e-153 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NDMLAEPG_00023 2.8e-126
NDMLAEPG_00024 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDMLAEPG_00025 8.3e-105 tatD L hydrolase, TatD family
NDMLAEPG_00026 1.7e-86 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NDMLAEPG_00027 7.5e-134 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NDMLAEPG_00028 1.2e-22 veg S Biofilm formation stimulator VEG
NDMLAEPG_00029 1.7e-90 S Alpha/beta hydrolase of unknown function (DUF915)
NDMLAEPG_00030 4.2e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
NDMLAEPG_00031 6.6e-46 argR K Regulates arginine biosynthesis genes
NDMLAEPG_00032 2.8e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NDMLAEPG_00033 1.3e-155 amtB P ammonium transporter
NDMLAEPG_00035 5.6e-89 sip L Belongs to the 'phage' integrase family
NDMLAEPG_00036 8.3e-84 S Domain of unknown function DUF1829
NDMLAEPG_00037 4.2e-22
NDMLAEPG_00038 7.6e-67 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NDMLAEPG_00039 2.4e-10
NDMLAEPG_00042 1.6e-39 XK27_10050 K Peptidase S24-like
NDMLAEPG_00045 6.4e-14 K Cro/C1-type HTH DNA-binding domain
NDMLAEPG_00048 8.9e-14 cro K Helix-turn-helix XRE-family like proteins
NDMLAEPG_00049 5.4e-43 S DNA binding
NDMLAEPG_00056 1.8e-53 S Putative HNHc nuclease
NDMLAEPG_00057 1.3e-30 L N-terminal phage replisome organiser (Phage_rep_org_N)
NDMLAEPG_00060 1.2e-25
NDMLAEPG_00061 9.4e-66
NDMLAEPG_00070 6.4e-33 arpU S Phage transcriptional regulator, ArpU family
NDMLAEPG_00071 6.1e-55 V Abi-like protein
NDMLAEPG_00073 1.1e-71 L HNH nucleases
NDMLAEPG_00074 4.3e-83 L Phage terminase, small subunit
NDMLAEPG_00075 0.0 S Phage Terminase
NDMLAEPG_00077 2.6e-198 S Phage portal protein
NDMLAEPG_00078 1.6e-113 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NDMLAEPG_00079 4.2e-196 S Phage capsid family
NDMLAEPG_00080 4.1e-21 S Phage gp6-like head-tail connector protein
NDMLAEPG_00081 4.5e-53 S Phage head-tail joining protein
NDMLAEPG_00082 2.7e-51 S Bacteriophage HK97-gp10, putative tail-component
NDMLAEPG_00083 3e-55 S Protein of unknown function (DUF806)
NDMLAEPG_00084 3.5e-78 S Phage tail tube protein
NDMLAEPG_00085 9.8e-17 S Phage tail assembly chaperone proteins, TAC
NDMLAEPG_00087 1.9e-18 M Phage tail tape measure protein TP901
NDMLAEPG_00088 1.3e-258 M Phage tail tape measure protein TP901
NDMLAEPG_00089 2.1e-77 S Phage tail protein
NDMLAEPG_00090 8e-119 rny D peptidase
NDMLAEPG_00092 4.9e-36 S Calcineurin-like phosphoesterase
NDMLAEPG_00094 2e-69 rny D Peptidase family M23
NDMLAEPG_00095 9.8e-74 M transferase activity, transferring glycosyl groups
NDMLAEPG_00096 5.8e-57 cps3F
NDMLAEPG_00097 2e-160 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
NDMLAEPG_00098 3.7e-65 S Glycosyltransferase like family 2
NDMLAEPG_00099 1.6e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
NDMLAEPG_00100 1.8e-95 M Core-2/I-Branching enzyme
NDMLAEPG_00101 2e-91 rfbP M Bacterial sugar transferase
NDMLAEPG_00102 1.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NDMLAEPG_00103 4.6e-111 ywqE 3.1.3.48 GM PHP domain protein
NDMLAEPG_00104 9.3e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NDMLAEPG_00105 2.6e-77 epsB M biosynthesis protein
NDMLAEPG_00106 3.2e-214 ugd 1.1.1.22 M UDP binding domain
NDMLAEPG_00107 1e-42
NDMLAEPG_00108 1.5e-38 S Acyltransferase family
NDMLAEPG_00109 6.3e-130 S Membrane protein involved in the export of O-antigen and teichoic acid
NDMLAEPG_00110 5.8e-26 S Acetyltransferase (Isoleucine patch superfamily)
NDMLAEPG_00111 1.3e-42 M Glycosyltransferase like family 2
NDMLAEPG_00114 2.6e-37 S Glycosyl transferase family 2
NDMLAEPG_00115 3.6e-143 M Glycosyl transferase family 2
NDMLAEPG_00116 6.8e-47 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
NDMLAEPG_00117 1.9e-120 G Glycosyltransferase Family 4
NDMLAEPG_00118 9.7e-174 rgpAc GT4 M Domain of unknown function (DUF1972)
NDMLAEPG_00120 2e-80 S response to antibiotic
NDMLAEPG_00121 9.8e-27 S zinc-ribbon domain
NDMLAEPG_00122 9.4e-118 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
NDMLAEPG_00123 9.9e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NDMLAEPG_00124 6.2e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NDMLAEPG_00125 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NDMLAEPG_00126 1.2e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NDMLAEPG_00127 1.3e-75 S Glycosyltransferase like family 2
NDMLAEPG_00128 2.5e-61 S Glycosyltransferase like family 2
NDMLAEPG_00129 2.6e-117 cps1D M Domain of unknown function (DUF4422)
NDMLAEPG_00130 3e-39 S CAAX protease self-immunity
NDMLAEPG_00131 9.1e-89 yvyE 3.4.13.9 S YigZ family
NDMLAEPG_00132 2.3e-58 S Haloacid dehalogenase-like hydrolase
NDMLAEPG_00133 2.9e-153 EGP Major facilitator Superfamily
NDMLAEPG_00135 2e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NDMLAEPG_00136 1.2e-27 yraB K transcriptional regulator
NDMLAEPG_00137 9.8e-90 S NADPH-dependent FMN reductase
NDMLAEPG_00138 1e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NDMLAEPG_00139 1.5e-55 S ECF transporter, substrate-specific component
NDMLAEPG_00140 2.5e-96 znuB U ABC 3 transport family
NDMLAEPG_00141 1e-98 fhuC P ABC transporter
NDMLAEPG_00142 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
NDMLAEPG_00143 7.6e-38
NDMLAEPG_00144 6.5e-54 XK27_01040 S Protein of unknown function (DUF1129)
NDMLAEPG_00145 5.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NDMLAEPG_00146 3.4e-23 yyzM S Bacterial protein of unknown function (DUF951)
NDMLAEPG_00147 1.8e-108 spo0J K Belongs to the ParB family
NDMLAEPG_00148 6.5e-118 soj D Sporulation initiation inhibitor
NDMLAEPG_00149 1.4e-81 noc K Belongs to the ParB family
NDMLAEPG_00150 4e-101 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NDMLAEPG_00151 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NDMLAEPG_00152 2.4e-109 3.1.4.46 C phosphodiesterase
NDMLAEPG_00153 0.0 pacL 3.6.3.8 P P-type ATPase
NDMLAEPG_00154 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
NDMLAEPG_00155 1.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NDMLAEPG_00157 2.3e-63 srtA 3.4.22.70 M sortase family
NDMLAEPG_00158 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NDMLAEPG_00159 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NDMLAEPG_00160 1.1e-33
NDMLAEPG_00161 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NDMLAEPG_00162 1e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NDMLAEPG_00163 1.5e-96 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NDMLAEPG_00164 4.7e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
NDMLAEPG_00165 1.1e-39 ybjQ S Belongs to the UPF0145 family
NDMLAEPG_00166 2.5e-08
NDMLAEPG_00167 8e-96 V ABC transporter, ATP-binding protein
NDMLAEPG_00168 1.1e-41 gntR1 K Transcriptional regulator, GntR family
NDMLAEPG_00169 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
NDMLAEPG_00170 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NDMLAEPG_00171 4.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
NDMLAEPG_00172 2.2e-107 terC P Integral membrane protein TerC family
NDMLAEPG_00173 1.6e-38 K Transcriptional regulator
NDMLAEPG_00174 1.3e-95 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NDMLAEPG_00175 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NDMLAEPG_00176 4.5e-102 tcyB E ABC transporter
NDMLAEPG_00177 3.2e-29 ponA V the current gene model (or a revised gene model) may contain a frame shift
NDMLAEPG_00178 6.1e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NDMLAEPG_00179 5.9e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NDMLAEPG_00180 1.2e-209 mtlR K Mga helix-turn-helix domain
NDMLAEPG_00181 9.8e-177 yjcE P Sodium proton antiporter
NDMLAEPG_00182 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NDMLAEPG_00183 4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
NDMLAEPG_00184 9.5e-69 dhaL 2.7.1.121 S Dak2
NDMLAEPG_00185 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NDMLAEPG_00186 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NDMLAEPG_00187 6.5e-61 K Bacterial regulatory proteins, tetR family
NDMLAEPG_00188 1.3e-209 brnQ U Component of the transport system for branched-chain amino acids
NDMLAEPG_00190 1.7e-111 endA F DNA RNA non-specific endonuclease
NDMLAEPG_00191 4.1e-75 XK27_02070 S Nitroreductase family
NDMLAEPG_00192 3.7e-62 cadA 3.6.3.3, 3.6.3.5 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
NDMLAEPG_00193 3.1e-104 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
NDMLAEPG_00194 3.8e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
NDMLAEPG_00195 4.7e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
NDMLAEPG_00196 9.4e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NDMLAEPG_00197 5.5e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
NDMLAEPG_00198 2e-76 azlC E branched-chain amino acid
NDMLAEPG_00199 2e-31 azlD S Branched-chain amino acid transport protein (AzlD)
NDMLAEPG_00200 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
NDMLAEPG_00201 1.6e-55 jag S R3H domain protein
NDMLAEPG_00202 7e-23 S Cytochrome B5
NDMLAEPG_00203 2.3e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
NDMLAEPG_00204 7.6e-60
NDMLAEPG_00205 1.3e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NDMLAEPG_00206 6.6e-156 nrnB S DHHA1 domain
NDMLAEPG_00207 1.5e-91 yunF F Protein of unknown function DUF72
NDMLAEPG_00208 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
NDMLAEPG_00209 5.4e-13
NDMLAEPG_00210 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NDMLAEPG_00211 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NDMLAEPG_00212 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NDMLAEPG_00213 4.1e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NDMLAEPG_00214 4.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
NDMLAEPG_00215 7.7e-61 M ErfK YbiS YcfS YnhG
NDMLAEPG_00217 2.6e-84 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NDMLAEPG_00218 1.2e-180 pbuG S permease
NDMLAEPG_00220 1.8e-78 S Cell surface protein
NDMLAEPG_00222 4.2e-256 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
NDMLAEPG_00223 6.3e-61
NDMLAEPG_00224 3.6e-41 rpmE2 J Ribosomal protein L31
NDMLAEPG_00225 5.3e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NDMLAEPG_00226 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NDMLAEPG_00228 1.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NDMLAEPG_00229 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NDMLAEPG_00230 1.8e-32 ywiB S Domain of unknown function (DUF1934)
NDMLAEPG_00231 2e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
NDMLAEPG_00232 3.3e-205 ywfO S HD domain protein
NDMLAEPG_00233 7.5e-88 S hydrolase
NDMLAEPG_00234 2e-105 ydcZ S Putative inner membrane exporter, YdcZ
NDMLAEPG_00235 1.3e-63
NDMLAEPG_00238 6.4e-40 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
NDMLAEPG_00239 2.3e-22
NDMLAEPG_00240 3e-56 spoVK O ATPase family associated with various cellular activities (AAA)
NDMLAEPG_00242 2.2e-86 S overlaps another CDS with the same product name
NDMLAEPG_00243 1.6e-125 S overlaps another CDS with the same product name
NDMLAEPG_00244 1.9e-98 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NDMLAEPG_00245 1.2e-20 ytkL S Belongs to the UPF0173 family
NDMLAEPG_00246 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NDMLAEPG_00247 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NDMLAEPG_00248 3.6e-17 yneR
NDMLAEPG_00249 1.5e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NDMLAEPG_00250 2.2e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
NDMLAEPG_00251 3.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NDMLAEPG_00252 3.8e-152 mdtG EGP Major facilitator Superfamily
NDMLAEPG_00253 3.8e-14 yobS K transcriptional regulator
NDMLAEPG_00254 2.8e-109 glcU U sugar transport
NDMLAEPG_00255 4.4e-170 yjjP S Putative threonine/serine exporter
NDMLAEPG_00256 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
NDMLAEPG_00257 2.2e-96 yicL EG EamA-like transporter family
NDMLAEPG_00258 3.5e-223 pepF E Oligopeptidase F
NDMLAEPG_00259 1.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NDMLAEPG_00260 4.4e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NDMLAEPG_00261 1.1e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
NDMLAEPG_00262 8.4e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NDMLAEPG_00263 4e-23 relB L RelB antitoxin
NDMLAEPG_00265 2.9e-172 S Putative peptidoglycan binding domain
NDMLAEPG_00266 1.2e-31 K Transcriptional regulator, MarR family
NDMLAEPG_00267 3.1e-216 XK27_09600 V ABC transporter, ATP-binding protein
NDMLAEPG_00268 3.1e-229 V ABC transporter transmembrane region
NDMLAEPG_00270 3.3e-96 S Domain of unknown function DUF87
NDMLAEPG_00272 6.3e-85 yxeH S hydrolase
NDMLAEPG_00273 9e-114 K response regulator
NDMLAEPG_00274 1.1e-272 vicK 2.7.13.3 T Histidine kinase
NDMLAEPG_00275 4.6e-103 yycH S YycH protein
NDMLAEPG_00276 5.6e-80 yycI S YycH protein
NDMLAEPG_00277 1.8e-30 yyaQ S YjbR
NDMLAEPG_00278 1.3e-116 vicX 3.1.26.11 S domain protein
NDMLAEPG_00279 3.7e-145 htrA 3.4.21.107 O serine protease
NDMLAEPG_00280 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NDMLAEPG_00281 4.4e-40 1.6.5.2 GM NAD(P)H-binding
NDMLAEPG_00282 3.3e-25 K MarR family transcriptional regulator
NDMLAEPG_00283 5.9e-88 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
NDMLAEPG_00284 1.7e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NDMLAEPG_00285 4.2e-208 G glycerol-3-phosphate transporter
NDMLAEPG_00286 5.9e-30 L Helix-turn-helix domain
NDMLAEPG_00287 3.6e-69 L HTH-like domain
NDMLAEPG_00288 1.9e-87 pac DM Glucan-binding protein C
NDMLAEPG_00290 2.6e-11 D Antitoxin component of a toxin-antitoxin (TA) module
NDMLAEPG_00291 2.7e-22 S PIN domain
NDMLAEPG_00292 8.5e-213 V N-6 DNA Methylase
NDMLAEPG_00293 7.3e-60 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
NDMLAEPG_00295 3.5e-69
NDMLAEPG_00296 8.9e-42 L Protein of unknown function (DUF3991)
NDMLAEPG_00297 2.4e-165 topA2 5.99.1.2 G Topoisomerase IA
NDMLAEPG_00300 5.8e-149 clpB O Belongs to the ClpA ClpB family
NDMLAEPG_00304 1.1e-218 U TraM recognition site of TraD and TraG
NDMLAEPG_00305 1.7e-75
NDMLAEPG_00307 2.7e-27
NDMLAEPG_00308 3.8e-191 U type IV secretory pathway VirB4
NDMLAEPG_00310 2.5e-29 M CHAP domain
NDMLAEPG_00314 1.9e-32 sip L Belongs to the 'phage' integrase family
NDMLAEPG_00315 1.4e-218 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NDMLAEPG_00316 1.4e-79 sip L Belongs to the 'phage' integrase family
NDMLAEPG_00317 1.4e-98 V Abi-like protein
NDMLAEPG_00318 2.4e-30
NDMLAEPG_00319 4.8e-29 S Domain of unknown function (DUF4352)
NDMLAEPG_00320 6.1e-37 E IrrE N-terminal-like domain
NDMLAEPG_00321 2.3e-45 K addiction module antidote protein HigA
NDMLAEPG_00322 8.3e-12 K Cro/C1-type HTH DNA-binding domain
NDMLAEPG_00323 6.6e-19
NDMLAEPG_00328 8.6e-163 D AAA domain
NDMLAEPG_00329 5.4e-102 S AAA domain
NDMLAEPG_00330 4.6e-51
NDMLAEPG_00331 1.3e-38
NDMLAEPG_00332 1.6e-81
NDMLAEPG_00333 2.9e-261 L Helicase C-terminal domain protein
NDMLAEPG_00334 0.0 L Primase C terminal 2 (PriCT-2)
NDMLAEPG_00335 8.8e-45 S magnesium ion binding
NDMLAEPG_00336 2.1e-16
NDMLAEPG_00344 3.8e-11 arpU S Phage transcriptional regulator, ArpU family
NDMLAEPG_00346 8.4e-23
NDMLAEPG_00347 2.6e-167 S Terminase RNAseH like domain
NDMLAEPG_00348 7.4e-145 S Phage portal protein, SPP1 Gp6-like
NDMLAEPG_00349 3.7e-96 S Phage minor capsid protein 2
NDMLAEPG_00351 6.3e-17 S Phage minor structural protein GP20
NDMLAEPG_00352 1.3e-98 S T=7 icosahedral viral capsid
NDMLAEPG_00353 4.4e-14
NDMLAEPG_00354 9.7e-29 S Minor capsid protein
NDMLAEPG_00355 3.5e-16 S Minor capsid protein
NDMLAEPG_00356 1e-16 S Minor capsid protein from bacteriophage
NDMLAEPG_00357 1.3e-37 N domain, Protein
NDMLAEPG_00359 8.2e-39 S Bacteriophage Gp15 protein
NDMLAEPG_00360 1.3e-106 M Phage tail tape measure protein TP901
NDMLAEPG_00361 2.7e-61 S Phage tail protein
NDMLAEPG_00362 1.8e-102 M Prophage endopeptidase tail
NDMLAEPG_00364 7.9e-55 M Collagen binding domain
NDMLAEPG_00365 1.1e-201 L Psort location Cytoplasmic, score
NDMLAEPG_00366 5.3e-33
NDMLAEPG_00367 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NDMLAEPG_00368 2.1e-67
NDMLAEPG_00369 1.3e-151
NDMLAEPG_00370 1.8e-63
NDMLAEPG_00371 2.5e-262 traK U TraM recognition site of TraD and TraG
NDMLAEPG_00372 1.9e-80
NDMLAEPG_00373 3.7e-87
NDMLAEPG_00374 3.8e-194 M CHAP domain
NDMLAEPG_00375 1.3e-217 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
NDMLAEPG_00376 0.0 traE U AAA-like domain
NDMLAEPG_00377 6.8e-116
NDMLAEPG_00378 1.7e-36
NDMLAEPG_00379 6.7e-51 S Cag pathogenicity island, type IV secretory system
NDMLAEPG_00380 3.9e-105
NDMLAEPG_00381 1.4e-50
NDMLAEPG_00382 0.0 L MobA MobL family protein
NDMLAEPG_00383 6.1e-26
NDMLAEPG_00384 8.9e-41
NDMLAEPG_00385 6.6e-114 S protein conserved in bacteria
NDMLAEPG_00386 5.9e-28
NDMLAEPG_00387 3.1e-41 relB L Addiction module antitoxin, RelB DinJ family
NDMLAEPG_00388 4.1e-161 repA S Replication initiator protein A
NDMLAEPG_00390 9e-147 D CobQ CobB MinD ParA nucleotide binding domain protein
NDMLAEPG_00391 1.2e-83 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NDMLAEPG_00392 2.2e-17 marR K Transcriptional regulator, MarR family
NDMLAEPG_00393 1.5e-10 S Protein of unknown function (DUF2992)
NDMLAEPG_00395 1.3e-81 I Polyketide cyclase / dehydrase and lipid transport
NDMLAEPG_00396 1.8e-144 MA20_38045 S cyclase family
NDMLAEPG_00398 3.5e-282 albVII I AMP-binding enzyme C-terminal domain
NDMLAEPG_00399 1.6e-08 acpS 2.7.6.3, 2.7.8.7, 3.2.1.52, 4.2.1.136, 4.3.1.14, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NDMLAEPG_00400 7.5e-117 tpm 2.1.1.67 Q Methyltransferase
NDMLAEPG_00402 1.5e-225 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NDMLAEPG_00403 1.9e-231 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NDMLAEPG_00404 2.5e-12 K Helix-turn-helix domain
NDMLAEPG_00405 9.3e-100 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NDMLAEPG_00406 4e-11 S Protein of unknown function (DUF805)
NDMLAEPG_00407 1.5e-10 S Protein of unknown function (DUF805)
NDMLAEPG_00408 3e-73 L PFAM transposase IS200-family protein
NDMLAEPG_00410 2.8e-80 yvfR V ABC transporter
NDMLAEPG_00411 4.2e-53 yvfS V ABC-2 type transporter
NDMLAEPG_00412 3.2e-57 salK 2.7.13.3 T Histidine kinase
NDMLAEPG_00413 1.4e-75 desR K helix_turn_helix, Lux Regulon
NDMLAEPG_00414 1.6e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
NDMLAEPG_00415 1.8e-104 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NDMLAEPG_00418 7.7e-43 S YjcQ protein
NDMLAEPG_00420 2e-63
NDMLAEPG_00421 1.1e-142 xerS L Phage integrase family
NDMLAEPG_00422 2.2e-58 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NDMLAEPG_00423 5.7e-18 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NDMLAEPG_00424 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NDMLAEPG_00425 4.8e-32 P Heavy-metal-associated domain
NDMLAEPG_00426 1.5e-44 L hmm pf00665
NDMLAEPG_00427 5.6e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NDMLAEPG_00428 3.2e-85 dps P Ferritin-like domain
NDMLAEPG_00429 5.7e-159 L transposase, IS605 OrfB family
NDMLAEPG_00430 1.5e-55 tlpA2 L Transposase IS200 like
NDMLAEPG_00431 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
NDMLAEPG_00432 3e-11 S YjcQ protein
NDMLAEPG_00433 8.6e-62 qmcA O prohibitin homologues
NDMLAEPG_00434 2e-31 qmcA O prohibitin homologues
NDMLAEPG_00435 2.7e-26 S protein encoded in hypervariable junctions of pilus gene clusters
NDMLAEPG_00436 0.0 O Belongs to the peptidase S8 family
NDMLAEPG_00437 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NDMLAEPG_00439 1.8e-41 yjbH Q Thioredoxin
NDMLAEPG_00440 3.2e-97 pstS P Phosphate
NDMLAEPG_00441 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
NDMLAEPG_00442 3e-122 pstA P Phosphate transport system permease protein PstA
NDMLAEPG_00443 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NDMLAEPG_00444 1.8e-115 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NDMLAEPG_00445 7.9e-56 P Plays a role in the regulation of phosphate uptake
NDMLAEPG_00446 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NDMLAEPG_00447 1.1e-79 S VIT family
NDMLAEPG_00448 9.4e-84 S membrane
NDMLAEPG_00449 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
NDMLAEPG_00450 5.2e-65 hly S protein, hemolysin III
NDMLAEPG_00451 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
NDMLAEPG_00452 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NDMLAEPG_00455 1.5e-13
NDMLAEPG_00456 3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NDMLAEPG_00457 1.3e-158 ccpA K catabolite control protein A
NDMLAEPG_00458 3.7e-42 S VanZ like family
NDMLAEPG_00459 1.5e-119 yebC K Transcriptional regulatory protein
NDMLAEPG_00460 2.1e-102 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDMLAEPG_00461 4.7e-121 comGA NU Type II IV secretion system protein
NDMLAEPG_00462 5.7e-98 comGB NU type II secretion system
NDMLAEPG_00463 1.2e-27 comGC U competence protein ComGC
NDMLAEPG_00464 1.5e-13
NDMLAEPG_00466 5.5e-11 S Putative Competence protein ComGF
NDMLAEPG_00468 7.6e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
NDMLAEPG_00469 9.3e-184 cycA E Amino acid permease
NDMLAEPG_00470 3e-57 S Calcineurin-like phosphoesterase
NDMLAEPG_00471 1.9e-53 yutD S Protein of unknown function (DUF1027)
NDMLAEPG_00472 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NDMLAEPG_00473 7.8e-32 S Protein of unknown function (DUF1461)
NDMLAEPG_00474 3e-92 dedA S SNARE associated Golgi protein
NDMLAEPG_00475 6.1e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NDMLAEPG_00476 8.8e-50 yugI 5.3.1.9 J general stress protein
NDMLAEPG_00477 3.2e-118 lys 3.5.1.104 M Glycosyl hydrolases family 25
NDMLAEPG_00480 1.2e-10
NDMLAEPG_00481 3.4e-167 mbl D Cell shape determining protein MreB Mrl
NDMLAEPG_00482 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NDMLAEPG_00483 1.8e-12 S Protein of unknown function (DUF2969)
NDMLAEPG_00484 6.1e-187 rodA D Belongs to the SEDS family
NDMLAEPG_00485 6.6e-25 arsC 1.20.4.1 P Belongs to the ArsC family
NDMLAEPG_00486 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
NDMLAEPG_00487 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NDMLAEPG_00488 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NDMLAEPG_00489 4.4e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NDMLAEPG_00490 2.4e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NDMLAEPG_00491 5.8e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NDMLAEPG_00492 2.2e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NDMLAEPG_00493 3.3e-90 stp 3.1.3.16 T phosphatase
NDMLAEPG_00494 3.4e-191 KLT serine threonine protein kinase
NDMLAEPG_00495 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NDMLAEPG_00496 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
NDMLAEPG_00497 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NDMLAEPG_00498 4.5e-53 asp S Asp23 family, cell envelope-related function
NDMLAEPG_00499 2.8e-238 yloV S DAK2 domain fusion protein YloV
NDMLAEPG_00500 9.7e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NDMLAEPG_00501 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NDMLAEPG_00502 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDMLAEPG_00503 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NDMLAEPG_00504 4.7e-211 smc D Required for chromosome condensation and partitioning
NDMLAEPG_00505 9.1e-149 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NDMLAEPG_00506 7e-40 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NDMLAEPG_00507 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NDMLAEPG_00508 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NDMLAEPG_00509 1.1e-26 ylqC S Belongs to the UPF0109 family
NDMLAEPG_00510 5.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NDMLAEPG_00511 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NDMLAEPG_00512 5.7e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
NDMLAEPG_00513 7e-198 yfnA E amino acid
NDMLAEPG_00514 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NDMLAEPG_00515 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
NDMLAEPG_00516 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NDMLAEPG_00517 5.3e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NDMLAEPG_00518 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NDMLAEPG_00519 6.1e-19 S Tetratricopeptide repeat
NDMLAEPG_00520 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NDMLAEPG_00521 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NDMLAEPG_00522 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NDMLAEPG_00523 2.3e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NDMLAEPG_00524 1.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NDMLAEPG_00525 5e-23 ykzG S Belongs to the UPF0356 family
NDMLAEPG_00526 1.6e-24
NDMLAEPG_00527 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NDMLAEPG_00528 1.4e-31 1.1.1.27 C L-malate dehydrogenase activity
NDMLAEPG_00529 1.7e-23 yktA S Belongs to the UPF0223 family
NDMLAEPG_00530 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NDMLAEPG_00531 0.0 typA T GTP-binding protein TypA
NDMLAEPG_00532 6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NDMLAEPG_00533 7e-115 manY G PTS system
NDMLAEPG_00534 3.3e-148 manN G system, mannose fructose sorbose family IID component
NDMLAEPG_00535 1.6e-102 ftsW D Belongs to the SEDS family
NDMLAEPG_00536 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NDMLAEPG_00537 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NDMLAEPG_00538 7.2e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NDMLAEPG_00539 2.4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NDMLAEPG_00540 2.4e-131 ylbL T Belongs to the peptidase S16 family
NDMLAEPG_00541 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NDMLAEPG_00542 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NDMLAEPG_00543 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NDMLAEPG_00544 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NDMLAEPG_00545 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NDMLAEPG_00546 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NDMLAEPG_00547 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NDMLAEPG_00548 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NDMLAEPG_00549 1e-152 purD 6.3.4.13 F Belongs to the GARS family
NDMLAEPG_00550 1.5e-93 S Acyltransferase family
NDMLAEPG_00551 2.2e-194 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDMLAEPG_00552 3.9e-122 K LysR substrate binding domain
NDMLAEPG_00554 2.2e-20
NDMLAEPG_00555 6.2e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NDMLAEPG_00556 5.8e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
NDMLAEPG_00557 1.4e-50 comEA L Competence protein ComEA
NDMLAEPG_00558 2e-69 comEB 3.5.4.12 F ComE operon protein 2
NDMLAEPG_00559 1.4e-155 comEC S Competence protein ComEC
NDMLAEPG_00560 9.3e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
NDMLAEPG_00561 1.1e-112 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NDMLAEPG_00562 3e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NDMLAEPG_00563 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NDMLAEPG_00564 8.1e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NDMLAEPG_00565 1.5e-228 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NDMLAEPG_00566 1.8e-36 ypmB S Protein conserved in bacteria
NDMLAEPG_00567 4e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NDMLAEPG_00568 1e-235 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NDMLAEPG_00569 5.1e-56 dnaD L DnaD domain protein
NDMLAEPG_00570 4.4e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NDMLAEPG_00571 1.5e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NDMLAEPG_00572 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NDMLAEPG_00573 1.9e-93 M transferase activity, transferring glycosyl groups
NDMLAEPG_00574 1.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
NDMLAEPG_00575 1.3e-99 epsJ1 M Glycosyltransferase like family 2
NDMLAEPG_00578 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NDMLAEPG_00579 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NDMLAEPG_00580 1.8e-56 yqeY S YqeY-like protein
NDMLAEPG_00582 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
NDMLAEPG_00583 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NDMLAEPG_00584 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NDMLAEPG_00585 6.6e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NDMLAEPG_00586 2.9e-276 yfmR S ABC transporter, ATP-binding protein
NDMLAEPG_00587 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NDMLAEPG_00588 3.2e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NDMLAEPG_00589 8.6e-135 yvgN C Aldo keto reductase
NDMLAEPG_00590 2.4e-35 K helix_turn_helix, mercury resistance
NDMLAEPG_00591 1.3e-102 S Aldo keto reductase
NDMLAEPG_00593 7.2e-79 ypmR E GDSL-like Lipase/Acylhydrolase
NDMLAEPG_00594 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NDMLAEPG_00595 3.6e-24 yozE S Belongs to the UPF0346 family
NDMLAEPG_00596 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NDMLAEPG_00597 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NDMLAEPG_00598 6.2e-85 dprA LU DNA protecting protein DprA
NDMLAEPG_00599 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NDMLAEPG_00600 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NDMLAEPG_00601 5.8e-205 G PTS system Galactitol-specific IIC component
NDMLAEPG_00602 2.3e-81 K Bacterial regulatory proteins, tetR family
NDMLAEPG_00603 3.3e-129 yjjC V ATPases associated with a variety of cellular activities
NDMLAEPG_00604 5.2e-202 M Exporter of polyketide antibiotics
NDMLAEPG_00605 4e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NDMLAEPG_00606 2.3e-34 S Repeat protein
NDMLAEPG_00607 5.8e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NDMLAEPG_00609 1.7e-15
NDMLAEPG_00612 5.9e-87 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NDMLAEPG_00613 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NDMLAEPG_00614 9.1e-43 yodB K Transcriptional regulator, HxlR family
NDMLAEPG_00615 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NDMLAEPG_00616 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NDMLAEPG_00617 9.3e-129 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NDMLAEPG_00618 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
NDMLAEPG_00619 2.2e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NDMLAEPG_00620 6.4e-12
NDMLAEPG_00621 1.5e-143 iunH2 3.2.2.1 F nucleoside hydrolase
NDMLAEPG_00622 7.6e-43 XK27_03960 S Protein of unknown function (DUF3013)
NDMLAEPG_00623 5.8e-118 prmA J Ribosomal protein L11 methyltransferase
NDMLAEPG_00624 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NDMLAEPG_00625 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NDMLAEPG_00626 1.7e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NDMLAEPG_00627 6.7e-57 3.1.3.18 J HAD-hyrolase-like
NDMLAEPG_00628 5.2e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NDMLAEPG_00629 7.3e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NDMLAEPG_00630 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NDMLAEPG_00631 2.7e-204 pyrP F Permease
NDMLAEPG_00632 7.4e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NDMLAEPG_00633 2.2e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NDMLAEPG_00634 1.5e-84 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NDMLAEPG_00635 2.3e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NDMLAEPG_00636 9.8e-135 K Transcriptional regulator
NDMLAEPG_00637 6.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
NDMLAEPG_00638 8.6e-115 glcR K DeoR C terminal sensor domain
NDMLAEPG_00639 4.5e-171 patA 2.6.1.1 E Aminotransferase
NDMLAEPG_00640 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NDMLAEPG_00642 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NDMLAEPG_00643 2.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NDMLAEPG_00644 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
NDMLAEPG_00645 6.2e-21 S Family of unknown function (DUF5322)
NDMLAEPG_00646 5.5e-255 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NDMLAEPG_00647 1.8e-38
NDMLAEPG_00650 2.5e-149 EGP Sugar (and other) transporter
NDMLAEPG_00651 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
NDMLAEPG_00652 4.8e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NDMLAEPG_00653 1.9e-183 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NDMLAEPG_00654 4.2e-73 alkD L DNA alkylation repair enzyme
NDMLAEPG_00655 5e-23 EG EamA-like transporter family
NDMLAEPG_00656 1.1e-100 EG EamA-like transporter family
NDMLAEPG_00657 3.6e-150 S Tetratricopeptide repeat protein
NDMLAEPG_00658 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
NDMLAEPG_00659 8.1e-297 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NDMLAEPG_00660 7e-127 corA P CorA-like Mg2+ transporter protein
NDMLAEPG_00661 8.5e-161 nhaC C Na H antiporter NhaC
NDMLAEPG_00662 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NDMLAEPG_00663 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NDMLAEPG_00665 7.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NDMLAEPG_00666 2.9e-154 iscS 2.8.1.7 E Aminotransferase class V
NDMLAEPG_00667 3.7e-41 XK27_04120 S Putative amino acid metabolism
NDMLAEPG_00668 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NDMLAEPG_00669 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NDMLAEPG_00670 4.3e-15 S Protein of unknown function (DUF2929)
NDMLAEPG_00671 0.0 dnaE 2.7.7.7 L DNA polymerase
NDMLAEPG_00672 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NDMLAEPG_00673 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NDMLAEPG_00675 5e-39 ypaA S Protein of unknown function (DUF1304)
NDMLAEPG_00676 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NDMLAEPG_00677 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NDMLAEPG_00678 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NDMLAEPG_00679 1.2e-196 FbpA K Fibronectin-binding protein
NDMLAEPG_00680 3.1e-40 K Transcriptional regulator
NDMLAEPG_00681 2.2e-117 degV S EDD domain protein, DegV family
NDMLAEPG_00682 7.8e-71 lepB 3.4.21.89 U Signal peptidase, peptidase S26
NDMLAEPG_00683 2.4e-40 6.3.3.2 S ASCH
NDMLAEPG_00684 1.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NDMLAEPG_00685 1.7e-79 yjjH S Calcineurin-like phosphoesterase
NDMLAEPG_00686 3.1e-95 EG EamA-like transporter family
NDMLAEPG_00687 2.3e-85 natB CP ABC-type Na efflux pump, permease component
NDMLAEPG_00688 6.2e-112 natA S Domain of unknown function (DUF4162)
NDMLAEPG_00689 4.8e-23 K Acetyltransferase (GNAT) domain
NDMLAEPG_00691 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NDMLAEPG_00692 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NDMLAEPG_00693 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
NDMLAEPG_00694 9.1e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
NDMLAEPG_00695 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NDMLAEPG_00696 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NDMLAEPG_00697 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
NDMLAEPG_00698 4.5e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NDMLAEPG_00699 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
NDMLAEPG_00700 4.5e-90 recO L Involved in DNA repair and RecF pathway recombination
NDMLAEPG_00701 1e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NDMLAEPG_00702 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NDMLAEPG_00703 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NDMLAEPG_00704 3.5e-153 phoH T phosphate starvation-inducible protein PhoH
NDMLAEPG_00705 7.5e-83 lytH 3.5.1.28 M Ami_3
NDMLAEPG_00706 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NDMLAEPG_00707 5.9e-12 M Lysin motif
NDMLAEPG_00708 9.1e-129 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NDMLAEPG_00709 7.1e-59 ypbB 5.1.3.1 S Helix-turn-helix domain
NDMLAEPG_00710 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
NDMLAEPG_00711 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
NDMLAEPG_00712 7.1e-120 ica2 GT2 M Glycosyl transferase family group 2
NDMLAEPG_00713 4.8e-44
NDMLAEPG_00714 4.5e-12 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NDMLAEPG_00715 3.5e-82 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NDMLAEPG_00716 1.2e-176 thrC 4.2.3.1 E Threonine synthase
NDMLAEPG_00717 2.4e-128 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NDMLAEPG_00718 5.2e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NDMLAEPG_00719 5.6e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NDMLAEPG_00720 5e-57 S peptidoglycan catabolic process
NDMLAEPG_00721 2e-194 XK27_08315 M Sulfatase
NDMLAEPG_00723 6.4e-168 mdtG EGP Major facilitator Superfamily
NDMLAEPG_00724 6.3e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NDMLAEPG_00725 4.8e-83 treR K UTRA
NDMLAEPG_00726 3.3e-259 treB G phosphotransferase system
NDMLAEPG_00727 3.5e-63 3.1.3.73 G phosphoglycerate mutase
NDMLAEPG_00728 2.4e-82 pncA Q isochorismatase
NDMLAEPG_00729 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NDMLAEPG_00730 1.2e-103 ydhQ K UbiC transcription regulator-associated domain protein
NDMLAEPG_00731 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NDMLAEPG_00732 3.6e-41 K Transcriptional regulator, HxlR family
NDMLAEPG_00733 8.3e-164 C Luciferase-like monooxygenase
NDMLAEPG_00735 3.7e-96 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NDMLAEPG_00736 3.7e-119 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NDMLAEPG_00737 5.3e-190 G PTS system sugar-specific permease component
NDMLAEPG_00738 4.9e-32 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
NDMLAEPG_00739 6.2e-34 2.7.1.197, 2.7.1.200, 2.7.1.202 G to PTS fructose-specific enzyme IIA component
NDMLAEPG_00740 6e-110 2.7.1.194, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
NDMLAEPG_00741 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
NDMLAEPG_00742 1.4e-148 yedE S Sulphur transport
NDMLAEPG_00743 9.2e-101 selD 2.7.9.3 E AIR synthase related protein, C-terminal domain
NDMLAEPG_00744 2.4e-176 rnfC C RnfC Barrel sandwich hybrid domain
NDMLAEPG_00745 9e-29 yitW S Iron-sulfur cluster assembly protein
NDMLAEPG_00746 2.4e-110 selA 2.9.1.1 H Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
NDMLAEPG_00747 8.8e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
NDMLAEPG_00748 1.4e-137 selB J Elongation factor SelB, winged helix
NDMLAEPG_00749 2.2e-07 S Protein of unknown function (DUF3343)
NDMLAEPG_00750 1.2e-48 yedF O Belongs to the sulfur carrier protein TusA family
NDMLAEPG_00751 5.3e-223 ybeC E amino acid
NDMLAEPG_00752 5.6e-97 XK27_00825 S Sulfite exporter TauE/SafE
NDMLAEPG_00753 7.8e-143 5.1.1.4 E Proline racemase
NDMLAEPG_00754 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
NDMLAEPG_00755 1.6e-73 prdD S An automated process has identified a potential problem with this gene model
NDMLAEPG_00756 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
NDMLAEPG_00757 7.6e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
NDMLAEPG_00758 7.1e-26 S Psort location Cytoplasmic, score
NDMLAEPG_00759 3.3e-235 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
NDMLAEPG_00761 6.5e-116 ynjE 2.8.1.11 P Rhodanese Homology Domain
NDMLAEPG_00762 5.4e-17 yeeD O Belongs to the sulfur carrier protein TusA family
NDMLAEPG_00763 1.1e-23 yeeE S Sulphur transport
NDMLAEPG_00764 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NDMLAEPG_00765 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
NDMLAEPG_00766 1.7e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NDMLAEPG_00767 5.4e-128 cpoA GT4 M Glycosyltransferase, group 1 family protein
NDMLAEPG_00768 8.8e-162 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NDMLAEPG_00769 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NDMLAEPG_00770 1.1e-35 ptsH G phosphocarrier protein HPR
NDMLAEPG_00771 1.5e-15
NDMLAEPG_00772 0.0 clpE O Belongs to the ClpA ClpB family
NDMLAEPG_00773 6.6e-23 XK27_09445 S Domain of unknown function (DUF1827)
NDMLAEPG_00774 2.9e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NDMLAEPG_00775 0.0 rafA 3.2.1.22 G alpha-galactosidase
NDMLAEPG_00776 1.6e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NDMLAEPG_00777 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NDMLAEPG_00778 2.6e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NDMLAEPG_00779 5.9e-111 galR K Transcriptional regulator
NDMLAEPG_00780 4e-289 lacS G Transporter
NDMLAEPG_00781 0.0 lacL 3.2.1.23 G -beta-galactosidase
NDMLAEPG_00782 2.6e-29 yqkB S Belongs to the HesB IscA family
NDMLAEPG_00783 2.3e-65 yxkH G Polysaccharide deacetylase
NDMLAEPG_00784 9.6e-09
NDMLAEPG_00785 2.9e-53 K LysR substrate binding domain
NDMLAEPG_00786 2e-122 MA20_14895 S Conserved hypothetical protein 698
NDMLAEPG_00787 1.1e-199 nupG F Nucleoside
NDMLAEPG_00788 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NDMLAEPG_00789 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NDMLAEPG_00790 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NDMLAEPG_00791 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NDMLAEPG_00792 3.9e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NDMLAEPG_00793 9e-20 yaaA S S4 domain protein YaaA
NDMLAEPG_00794 9.3e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NDMLAEPG_00795 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NDMLAEPG_00796 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NDMLAEPG_00797 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
NDMLAEPG_00798 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NDMLAEPG_00799 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NDMLAEPG_00800 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
NDMLAEPG_00801 7.3e-117 S Glycosyl transferase family 2
NDMLAEPG_00802 7.4e-64 D peptidase
NDMLAEPG_00803 0.0 asnB 6.3.5.4 E Asparagine synthase
NDMLAEPG_00804 3.7e-37 yiiE S Protein of unknown function (DUF1211)
NDMLAEPG_00805 9.6e-31 yeeE S Sulphur transport
NDMLAEPG_00806 3e-105 yraQ S Predicted permease
NDMLAEPG_00807 1.8e-124 yvgN C Aldo keto reductase
NDMLAEPG_00810 6.3e-20 M domain protein
NDMLAEPG_00811 3e-35 agrA KT Response regulator of the LytR AlgR family
NDMLAEPG_00812 1e-43 2.7.13.3 T protein histidine kinase activity
NDMLAEPG_00813 0.0 pepN 3.4.11.2 E aminopeptidase
NDMLAEPG_00814 1.1e-35
NDMLAEPG_00816 4.5e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
NDMLAEPG_00817 4.2e-11 licT K transcriptional antiterminator
NDMLAEPG_00818 6.8e-39 licT K CAT RNA binding domain
NDMLAEPG_00819 6.8e-28 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NDMLAEPG_00820 2.4e-187 L Probable transposase
NDMLAEPG_00821 3.8e-39 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NDMLAEPG_00822 3e-89 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NDMLAEPG_00823 9e-63 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NDMLAEPG_00824 8.6e-38 S Replication initiator protein A (RepA) N-terminus
NDMLAEPG_00825 3.2e-109 L Initiator Replication protein
NDMLAEPG_00826 1.2e-08 yokH G regulation of fungal-type cell wall biogenesis
NDMLAEPG_00828 2.1e-47 L PLD-like domain
NDMLAEPG_00830 5.7e-56
NDMLAEPG_00831 5.4e-37 bCE_4747 S Beta-lactamase superfamily domain
NDMLAEPG_00832 2e-289 ybiT S ABC transporter, ATP-binding protein
NDMLAEPG_00833 1e-78 2.4.2.3 F Phosphorylase superfamily
NDMLAEPG_00834 1.1e-23
NDMLAEPG_00835 7.6e-112 dkg S reductase
NDMLAEPG_00836 7.7e-19 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDMLAEPG_00837 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NDMLAEPG_00838 1.1e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NDMLAEPG_00839 2.1e-46 EGP Transmembrane secretion effector
NDMLAEPG_00840 5.2e-137 purR 2.4.2.7 F pur operon repressor
NDMLAEPG_00841 6.6e-53 adhR K helix_turn_helix, mercury resistance
NDMLAEPG_00842 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NDMLAEPG_00843 2.5e-104 pfoS S Phosphotransferase system, EIIC
NDMLAEPG_00844 2.2e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDMLAEPG_00845 6.2e-152 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NDMLAEPG_00846 1.9e-196 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NDMLAEPG_00847 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
NDMLAEPG_00848 1.8e-98 M hydrolase, family 25
NDMLAEPG_00849 5.3e-16 S Bacteriophage holin of superfamily 6 (Holin_LLH)
NDMLAEPG_00853 4.7e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NDMLAEPG_00854 1.2e-160 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NDMLAEPG_00855 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NDMLAEPG_00856 2.1e-30 gtcA S Teichoic acid glycosylation protein
NDMLAEPG_00857 5e-115 rfbJ M Glycosyl transferase family 2
NDMLAEPG_00858 8.5e-34 S Predicted membrane protein (DUF2142)
NDMLAEPG_00859 7.3e-82
NDMLAEPG_00860 7.6e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NDMLAEPG_00861 1e-133 coaA 2.7.1.33 F Pantothenic acid kinase
NDMLAEPG_00862 6.3e-44 E GDSL-like Lipase/Acylhydrolase
NDMLAEPG_00863 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NDMLAEPG_00864 1.9e-190 glnPH2 P ABC transporter permease
NDMLAEPG_00865 2.5e-214 yjeM E Amino Acid
NDMLAEPG_00866 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
NDMLAEPG_00867 8.1e-107 tetA EGP Major facilitator Superfamily
NDMLAEPG_00868 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NDMLAEPG_00869 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NDMLAEPG_00870 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NDMLAEPG_00871 1.6e-55 ctsR K Belongs to the CtsR family
NDMLAEPG_00873 2.5e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NDMLAEPG_00874 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NDMLAEPG_00875 3.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NDMLAEPG_00876 5.5e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NDMLAEPG_00877 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NDMLAEPG_00881 4.9e-217 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NDMLAEPG_00882 7.2e-149 mepA V MATE efflux family protein
NDMLAEPG_00883 4.3e-150 lsa S ABC transporter
NDMLAEPG_00884 5.2e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NDMLAEPG_00885 8e-110 puuD S peptidase C26
NDMLAEPG_00886 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NDMLAEPG_00887 1.1e-25
NDMLAEPG_00888 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
NDMLAEPG_00889 6.6e-60 uspA T Universal stress protein family
NDMLAEPG_00891 2.5e-211 glnP P ABC transporter
NDMLAEPG_00892 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NDMLAEPG_00893 2.5e-146 XK27_08315 M Sulfatase
NDMLAEPG_00894 3.2e-129 S Bacterial membrane protein YfhO
NDMLAEPG_00895 8.8e-102 S Bacterial membrane protein, YfhO
NDMLAEPG_00896 8.5e-22 S Bacterial membrane protein, YfhO
NDMLAEPG_00897 2.9e-44 S Bacterial membrane protein, YfhO
NDMLAEPG_00898 3.6e-14
NDMLAEPG_00899 1.5e-55 S Psort location CytoplasmicMembrane, score
NDMLAEPG_00900 1.2e-145 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NDMLAEPG_00901 1.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
NDMLAEPG_00902 2.7e-156 XK27_09615 S reductase
NDMLAEPG_00903 5.4e-67 XK27_09620 S NADPH-dependent FMN reductase
NDMLAEPG_00904 1.6e-197 dtpT U amino acid peptide transporter
NDMLAEPG_00905 1.1e-07
NDMLAEPG_00907 5.9e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NDMLAEPG_00908 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
NDMLAEPG_00909 2.5e-90 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NDMLAEPG_00910 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NDMLAEPG_00911 3.6e-130 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NDMLAEPG_00912 8.2e-251 yhgF K Tex-like protein N-terminal domain protein
NDMLAEPG_00913 7.2e-45 ydcK S Belongs to the SprT family
NDMLAEPG_00915 1.3e-115 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDMLAEPG_00916 5.9e-129 mleP2 S Sodium Bile acid symporter family
NDMLAEPG_00917 4.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NDMLAEPG_00918 1e-33 S Enterocin A Immunity
NDMLAEPG_00919 3.8e-222 pepC 3.4.22.40 E Peptidase C1-like family
NDMLAEPG_00920 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
NDMLAEPG_00921 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NDMLAEPG_00922 5.4e-224 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NDMLAEPG_00923 8.2e-154 yacL S domain protein
NDMLAEPG_00924 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NDMLAEPG_00925 6.9e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NDMLAEPG_00926 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NDMLAEPG_00927 3.2e-109 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NDMLAEPG_00928 5.4e-71 yacP S YacP-like NYN domain
NDMLAEPG_00929 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NDMLAEPG_00930 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NDMLAEPG_00931 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
NDMLAEPG_00932 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NDMLAEPG_00933 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NDMLAEPG_00934 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NDMLAEPG_00935 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NDMLAEPG_00936 1.4e-54
NDMLAEPG_00937 1.6e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NDMLAEPG_00938 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NDMLAEPG_00939 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NDMLAEPG_00940 4.8e-45 nrdI F NrdI Flavodoxin like
NDMLAEPG_00941 1.2e-27 nrdH O Glutaredoxin
NDMLAEPG_00942 1.1e-75 rsmC 2.1.1.172 J Methyltransferase
NDMLAEPG_00943 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NDMLAEPG_00944 4.3e-210 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NDMLAEPG_00945 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NDMLAEPG_00946 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NDMLAEPG_00947 9.2e-29 yaaL S Protein of unknown function (DUF2508)
NDMLAEPG_00948 1.4e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NDMLAEPG_00949 3.9e-83 holB 2.7.7.7 L DNA polymerase III
NDMLAEPG_00950 1.4e-40 yabA L Involved in initiation control of chromosome replication
NDMLAEPG_00951 4.1e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NDMLAEPG_00952 4.7e-81 fat 3.1.2.21 I Acyl-ACP thioesterase
NDMLAEPG_00953 3.5e-140 ansA 3.5.1.1 EJ Asparaginase
NDMLAEPG_00954 3.7e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NDMLAEPG_00955 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NDMLAEPG_00956 8.4e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NDMLAEPG_00957 6.9e-257 uup S ABC transporter, ATP-binding protein
NDMLAEPG_00958 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NDMLAEPG_00959 1.4e-33 S CAAX protease self-immunity
NDMLAEPG_00960 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NDMLAEPG_00961 1.3e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NDMLAEPG_00962 2.5e-269 aha1 P COG COG0474 Cation transport ATPase
NDMLAEPG_00963 1.2e-295 ydaO E amino acid
NDMLAEPG_00964 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
NDMLAEPG_00965 9.3e-128 comFA L Helicase C-terminal domain protein
NDMLAEPG_00966 5.6e-44 comFC S Competence protein
NDMLAEPG_00967 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NDMLAEPG_00968 4.5e-94 yeaN P Major Facilitator Superfamily
NDMLAEPG_00969 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NDMLAEPG_00970 2.2e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NDMLAEPG_00971 2e-67 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
NDMLAEPG_00972 6e-86 K response regulator
NDMLAEPG_00973 1.2e-85 phoR 2.7.13.3 T Histidine kinase
NDMLAEPG_00974 2.4e-08 pspC KT PspC domain
NDMLAEPG_00975 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NDMLAEPG_00976 8.7e-133 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NDMLAEPG_00977 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NDMLAEPG_00978 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NDMLAEPG_00979 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NDMLAEPG_00980 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NDMLAEPG_00981 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NDMLAEPG_00982 5e-79 ylbE GM NAD dependent epimerase dehydratase family protein
NDMLAEPG_00983 7.5e-126 rapZ S Displays ATPase and GTPase activities
NDMLAEPG_00984 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NDMLAEPG_00985 1.8e-149 whiA K May be required for sporulation
NDMLAEPG_00986 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NDMLAEPG_00988 1.1e-136 cggR K Putative sugar-binding domain
NDMLAEPG_00989 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NDMLAEPG_00990 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NDMLAEPG_00991 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NDMLAEPG_00992 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NDMLAEPG_00993 2.2e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NDMLAEPG_00994 1.5e-103 K response regulator
NDMLAEPG_00995 1.8e-169 T PhoQ Sensor
NDMLAEPG_00996 6.7e-146 lmrP E Major Facilitator Superfamily
NDMLAEPG_00997 1.2e-179 clcA P chloride
NDMLAEPG_00998 2.8e-19 secG U Preprotein translocase
NDMLAEPG_00999 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NDMLAEPG_01000 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NDMLAEPG_01001 9.1e-42 yxjI
NDMLAEPG_01002 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
NDMLAEPG_01003 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NDMLAEPG_01004 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NDMLAEPG_01005 3.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NDMLAEPG_01006 1.9e-68 dnaQ 2.7.7.7 L DNA polymerase III
NDMLAEPG_01007 3.5e-115 murB 1.3.1.98 M Cell wall formation
NDMLAEPG_01008 2.4e-71 S Protein of unknown function (DUF1361)
NDMLAEPG_01009 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NDMLAEPG_01010 5.3e-68 ybbR S YbbR-like protein
NDMLAEPG_01011 4.4e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NDMLAEPG_01012 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NDMLAEPG_01013 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NDMLAEPG_01014 3.2e-21 cutC P Participates in the control of copper homeostasis
NDMLAEPG_01015 4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NDMLAEPG_01016 7.7e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NDMLAEPG_01017 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
NDMLAEPG_01018 1.7e-98 rrmA 2.1.1.187 H Methyltransferase
NDMLAEPG_01019 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NDMLAEPG_01020 1.6e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
NDMLAEPG_01021 3.5e-108 ymfF S Peptidase M16 inactive domain protein
NDMLAEPG_01022 1.3e-147 ymfH S Peptidase M16
NDMLAEPG_01023 8.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
NDMLAEPG_01024 2.9e-64 ymfM S Helix-turn-helix domain
NDMLAEPG_01025 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NDMLAEPG_01026 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NDMLAEPG_01027 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
NDMLAEPG_01028 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NDMLAEPG_01029 6e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NDMLAEPG_01030 7.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NDMLAEPG_01031 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NDMLAEPG_01032 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NDMLAEPG_01033 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NDMLAEPG_01034 1.8e-12 yajC U Preprotein translocase
NDMLAEPG_01036 4.3e-61 uspA T universal stress protein
NDMLAEPG_01038 2e-208 yfnA E Amino Acid
NDMLAEPG_01039 6.9e-117 lutA C Cysteine-rich domain
NDMLAEPG_01040 2.1e-245 lutB C 4Fe-4S dicluster domain
NDMLAEPG_01041 1.9e-66 yrjD S LUD domain
NDMLAEPG_01042 1e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NDMLAEPG_01043 7.5e-13
NDMLAEPG_01044 2.7e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NDMLAEPG_01045 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NDMLAEPG_01046 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NDMLAEPG_01047 2.1e-36 yrzL S Belongs to the UPF0297 family
NDMLAEPG_01048 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NDMLAEPG_01049 1.9e-33 yrzB S Belongs to the UPF0473 family
NDMLAEPG_01050 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NDMLAEPG_01051 9.5e-18 cvpA S Colicin V production protein
NDMLAEPG_01052 3.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NDMLAEPG_01053 9.9e-41 trxA O Belongs to the thioredoxin family
NDMLAEPG_01054 1.1e-60 yslB S Protein of unknown function (DUF2507)
NDMLAEPG_01055 2.2e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NDMLAEPG_01056 5.1e-42 S Phosphoesterase
NDMLAEPG_01059 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDMLAEPG_01060 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NDMLAEPG_01061 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NDMLAEPG_01062 3.1e-198 oatA I Acyltransferase
NDMLAEPG_01063 1.4e-16
NDMLAEPG_01065 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NDMLAEPG_01066 6.5e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
NDMLAEPG_01067 4e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
NDMLAEPG_01068 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NDMLAEPG_01069 1.2e-296 S membrane
NDMLAEPG_01070 1.5e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
NDMLAEPG_01071 1.8e-27 S Protein of unknown function (DUF3290)
NDMLAEPG_01072 3.3e-75 yviA S Protein of unknown function (DUF421)
NDMLAEPG_01074 4.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NDMLAEPG_01075 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NDMLAEPG_01076 1.1e-53 tag 3.2.2.20 L glycosylase
NDMLAEPG_01077 6e-72 usp6 T universal stress protein
NDMLAEPG_01079 5.1e-184 rarA L recombination factor protein RarA
NDMLAEPG_01080 3.4e-24 yueI S Protein of unknown function (DUF1694)
NDMLAEPG_01081 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NDMLAEPG_01082 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
NDMLAEPG_01083 2.9e-174 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NDMLAEPG_01084 6.4e-162 iscS2 2.8.1.7 E Aminotransferase class V
NDMLAEPG_01085 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NDMLAEPG_01086 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NDMLAEPG_01087 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NDMLAEPG_01088 8.1e-80 radC L DNA repair protein
NDMLAEPG_01089 4.5e-21 K Cold shock
NDMLAEPG_01090 3.6e-156 mreB D cell shape determining protein MreB
NDMLAEPG_01091 2.1e-88 mreC M Involved in formation and maintenance of cell shape
NDMLAEPG_01092 2e-54 mreD M rod shape-determining protein MreD
NDMLAEPG_01093 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NDMLAEPG_01094 1.8e-126 minD D Belongs to the ParA family
NDMLAEPG_01095 1.9e-94 glnP P ABC transporter permease
NDMLAEPG_01096 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NDMLAEPG_01097 3.7e-109 aatB ET ABC transporter substrate-binding protein
NDMLAEPG_01098 9.8e-100 D Alpha beta
NDMLAEPG_01100 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
NDMLAEPG_01101 2.2e-07 S Protein of unknown function (DUF3397)
NDMLAEPG_01102 1.5e-55 mraZ K Belongs to the MraZ family
NDMLAEPG_01103 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NDMLAEPG_01104 2.5e-11 ftsL D cell division protein FtsL
NDMLAEPG_01105 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
NDMLAEPG_01106 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NDMLAEPG_01107 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NDMLAEPG_01108 1.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NDMLAEPG_01109 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NDMLAEPG_01110 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NDMLAEPG_01111 9.8e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NDMLAEPG_01112 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NDMLAEPG_01113 3e-19 yggT S YGGT family
NDMLAEPG_01114 1.7e-81 ylmH S S4 domain protein
NDMLAEPG_01115 1.9e-61 divIVA D DivIVA domain protein
NDMLAEPG_01116 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NDMLAEPG_01117 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NDMLAEPG_01118 4.4e-74 draG O ADP-ribosylglycohydrolase
NDMLAEPG_01120 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
NDMLAEPG_01121 1.4e-92 T Calcineurin-like phosphoesterase superfamily domain
NDMLAEPG_01122 5.5e-49 lytE M LysM domain protein
NDMLAEPG_01123 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NDMLAEPG_01124 1.9e-243 lysP E amino acid
NDMLAEPG_01125 2.3e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
NDMLAEPG_01126 3.3e-271 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NDMLAEPG_01127 3.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDMLAEPG_01128 7.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
NDMLAEPG_01129 1.7e-82 lysR5 K LysR substrate binding domain
NDMLAEPG_01130 6.5e-119 yxaA S membrane transporter protein
NDMLAEPG_01131 2.6e-32 ywjH S Protein of unknown function (DUF1634)
NDMLAEPG_01132 4.1e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NDMLAEPG_01133 1.7e-225 pipD E Dipeptidase
NDMLAEPG_01134 2.3e-21 K helix_turn_helix multiple antibiotic resistance protein
NDMLAEPG_01135 7.6e-57 EGP Major facilitator Superfamily
NDMLAEPG_01136 3e-97 EGP Major facilitator Superfamily
NDMLAEPG_01137 5.6e-82 S L,D-transpeptidase catalytic domain
NDMLAEPG_01138 1.4e-113 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NDMLAEPG_01139 2.3e-17 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NDMLAEPG_01140 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NDMLAEPG_01141 7.2e-27 ydiI Q Thioesterase superfamily
NDMLAEPG_01142 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
NDMLAEPG_01143 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NDMLAEPG_01144 6.4e-114 degV S EDD domain protein, DegV family
NDMLAEPG_01145 1.8e-163 cadA P P-type ATPase
NDMLAEPG_01146 2.8e-41 cadA P P-type ATPase
NDMLAEPG_01147 1.8e-254 E Amino acid permease
NDMLAEPG_01148 3e-82 S Membrane
NDMLAEPG_01149 9.1e-50 cps3F
NDMLAEPG_01150 6.9e-106 L Belongs to the 'phage' integrase family
NDMLAEPG_01152 5.7e-08
NDMLAEPG_01153 2.3e-25 D nuclear chromosome segregation
NDMLAEPG_01156 2.3e-44 S Fic/DOC family
NDMLAEPG_01157 3.7e-13 S Fic/DOC family
NDMLAEPG_01160 1.1e-63 ruvB 3.6.4.12 L four-way junction helicase activity
NDMLAEPG_01164 2e-07 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
NDMLAEPG_01165 4.8e-19
NDMLAEPG_01166 5.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
NDMLAEPG_01167 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NDMLAEPG_01168 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NDMLAEPG_01169 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NDMLAEPG_01170 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NDMLAEPG_01171 1.2e-89 patB 4.4.1.8 E Aminotransferase, class I
NDMLAEPG_01172 9.7e-113 K response regulator
NDMLAEPG_01173 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
NDMLAEPG_01174 2.2e-90 lacX 5.1.3.3 G Aldose 1-epimerase
NDMLAEPG_01175 1.9e-20 G Transporter, major facilitator family protein
NDMLAEPG_01176 4.3e-116 G Transporter, major facilitator family protein
NDMLAEPG_01177 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NDMLAEPG_01178 1.4e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NDMLAEPG_01179 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NDMLAEPG_01180 3.4e-91 yueF S AI-2E family transporter
NDMLAEPG_01181 2.6e-97 ygaC J Belongs to the UPF0374 family
NDMLAEPG_01182 9.4e-192 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NDMLAEPG_01183 2.9e-68 recX 2.4.1.337 GT4 S Regulatory protein RecX
NDMLAEPG_01184 1.1e-19 yvrI K RNA polymerase sigma factor, sigma-70 family
NDMLAEPG_01185 7e-217 yjeM E Amino Acid
NDMLAEPG_01187 1.8e-30 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NDMLAEPG_01188 2.5e-179 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
NDMLAEPG_01189 1.5e-55 S COG NOG19168 non supervised orthologous group
NDMLAEPG_01191 7.2e-58 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
NDMLAEPG_01192 2e-21 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
NDMLAEPG_01193 6.8e-276 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NDMLAEPG_01194 6.6e-87 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NDMLAEPG_01196 5.9e-162 potE2 E amino acid
NDMLAEPG_01197 1.1e-147 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NDMLAEPG_01198 9.7e-114 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NDMLAEPG_01199 7.3e-57 racA K Domain of unknown function (DUF1836)
NDMLAEPG_01200 8.3e-82 yitS S EDD domain protein, DegV family
NDMLAEPG_01201 3.2e-45 yjaB_1 K Acetyltransferase (GNAT) domain
NDMLAEPG_01202 4e-250 M Collagen binding domain
NDMLAEPG_01203 4.5e-49 K DNA-binding transcription factor activity
NDMLAEPG_01204 7e-62 S SnoaL-like domain
NDMLAEPG_01205 2.7e-100 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NDMLAEPG_01206 3.3e-40 K Helix-turn-helix domain
NDMLAEPG_01207 2.8e-63 S Phage derived protein Gp49-like (DUF891)
NDMLAEPG_01208 2.2e-105 L Integrase
NDMLAEPG_01209 3.6e-45
NDMLAEPG_01210 1.9e-08 K Helix-turn-helix domain
NDMLAEPG_01211 5.3e-121 lys 3.5.1.104 M and GP 10880731
NDMLAEPG_01212 2.1e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NDMLAEPG_01213 3.8e-69 coiA 3.6.4.12 S Competence protein
NDMLAEPG_01214 1.5e-232 pepF E oligoendopeptidase F
NDMLAEPG_01217 1.1e-08
NDMLAEPG_01219 1e-76 S DNA primase
NDMLAEPG_01220 4.6e-31 L DNA replication protein
NDMLAEPG_01230 2.1e-07
NDMLAEPG_01240 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NDMLAEPG_01241 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NDMLAEPG_01242 9.7e-194 cycA E Amino acid permease
NDMLAEPG_01243 1.1e-186 ytgP S Polysaccharide biosynthesis protein
NDMLAEPG_01244 1.1e-61 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NDMLAEPG_01245 1.2e-80 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NDMLAEPG_01246 5.1e-193 pepV 3.5.1.18 E dipeptidase PepV
NDMLAEPG_01247 3.3e-182 S Protein of unknown function DUF262
NDMLAEPG_01249 3e-36
NDMLAEPG_01250 1.3e-65 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NDMLAEPG_01251 4.2e-61 marR K Transcriptional regulator, MarR family
NDMLAEPG_01252 6.4e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDMLAEPG_01253 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDMLAEPG_01254 6.5e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NDMLAEPG_01255 1.4e-98 IQ reductase
NDMLAEPG_01256 1.8e-194 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NDMLAEPG_01257 7.9e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NDMLAEPG_01258 1.5e-63 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NDMLAEPG_01259 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NDMLAEPG_01260 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NDMLAEPG_01261 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NDMLAEPG_01262 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NDMLAEPG_01263 1.5e-230 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NDMLAEPG_01264 1.2e-239 pgi 5.3.1.9 G Belongs to the GPI family
NDMLAEPG_01265 2.7e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NDMLAEPG_01266 5.7e-119 gla U Major intrinsic protein
NDMLAEPG_01267 5.8e-45 ykuL S CBS domain
NDMLAEPG_01268 1.5e-60 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NDMLAEPG_01269 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NDMLAEPG_01270 2.1e-88 ykuT M mechanosensitive ion channel
NDMLAEPG_01272 1e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NDMLAEPG_01273 2e-21 yheA S Belongs to the UPF0342 family
NDMLAEPG_01274 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
NDMLAEPG_01275 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NDMLAEPG_01277 5.4e-53 hit FG histidine triad
NDMLAEPG_01278 2.8e-94 ecsA V ABC transporter, ATP-binding protein
NDMLAEPG_01279 1.3e-72 ecsB U ABC transporter
NDMLAEPG_01280 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
NDMLAEPG_01281 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NDMLAEPG_01282 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NDMLAEPG_01283 6.8e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NDMLAEPG_01284 9e-240 sftA D Belongs to the FtsK SpoIIIE SftA family
NDMLAEPG_01285 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NDMLAEPG_01286 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
NDMLAEPG_01287 6.7e-69 ybhL S Belongs to the BI1 family
NDMLAEPG_01288 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDMLAEPG_01289 3.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NDMLAEPG_01290 2.1e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NDMLAEPG_01291 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NDMLAEPG_01292 1.6e-79 dnaB L replication initiation and membrane attachment
NDMLAEPG_01293 2.2e-107 dnaI L Primosomal protein DnaI
NDMLAEPG_01294 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NDMLAEPG_01295 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NDMLAEPG_01296 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NDMLAEPG_01297 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NDMLAEPG_01298 2.5e-71 yqeG S HAD phosphatase, family IIIA
NDMLAEPG_01299 7.9e-181 yqeH S Ribosome biogenesis GTPase YqeH
NDMLAEPG_01300 1e-29 yhbY J RNA-binding protein
NDMLAEPG_01301 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NDMLAEPG_01302 1e-70 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NDMLAEPG_01303 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NDMLAEPG_01304 4.2e-82 H Nodulation protein S (NodS)
NDMLAEPG_01305 1.3e-122 ylbM S Belongs to the UPF0348 family
NDMLAEPG_01306 2e-57 yceD S Uncharacterized ACR, COG1399
NDMLAEPG_01307 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NDMLAEPG_01308 1.2e-88 plsC 2.3.1.51 I Acyltransferase
NDMLAEPG_01309 1.4e-93 yabB 2.1.1.223 L Methyltransferase small domain
NDMLAEPG_01310 1.5e-27 yazA L GIY-YIG catalytic domain protein
NDMLAEPG_01311 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
NDMLAEPG_01312 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NDMLAEPG_01313 6.9e-37
NDMLAEPG_01314 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NDMLAEPG_01315 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NDMLAEPG_01316 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NDMLAEPG_01317 7.9e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NDMLAEPG_01318 8.6e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NDMLAEPG_01320 3.1e-111 K response regulator
NDMLAEPG_01321 5e-167 arlS 2.7.13.3 T Histidine kinase
NDMLAEPG_01322 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NDMLAEPG_01323 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NDMLAEPG_01324 4.3e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NDMLAEPG_01325 7.3e-105
NDMLAEPG_01326 7.2e-117
NDMLAEPG_01327 1.3e-41 dut S dUTPase
NDMLAEPG_01328 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NDMLAEPG_01329 3.7e-46 yqhY S Asp23 family, cell envelope-related function
NDMLAEPG_01330 1.9e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NDMLAEPG_01331 1.7e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NDMLAEPG_01332 1.2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NDMLAEPG_01333 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NDMLAEPG_01334 4.7e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NDMLAEPG_01335 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NDMLAEPG_01336 6.6e-49 argR K Regulates arginine biosynthesis genes
NDMLAEPG_01337 4.2e-178 recN L May be involved in recombinational repair of damaged DNA
NDMLAEPG_01338 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NDMLAEPG_01339 2.2e-30 ynzC S UPF0291 protein
NDMLAEPG_01340 5.9e-27 yneF S UPF0154 protein
NDMLAEPG_01341 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
NDMLAEPG_01342 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NDMLAEPG_01343 1.2e-74 yciQ P membrane protein (DUF2207)
NDMLAEPG_01344 3e-19 D nuclear chromosome segregation
NDMLAEPG_01345 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NDMLAEPG_01346 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NDMLAEPG_01347 7.4e-70 gluP 3.4.21.105 S Peptidase, S54 family
NDMLAEPG_01348 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
NDMLAEPG_01349 4.7e-158 glk 2.7.1.2 G Glucokinase
NDMLAEPG_01350 2.7e-46 yqhL P Rhodanese-like protein
NDMLAEPG_01351 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
NDMLAEPG_01352 1.9e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NDMLAEPG_01353 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
NDMLAEPG_01354 1.3e-45 glnR K Transcriptional regulator
NDMLAEPG_01355 2.2e-246 glnA 6.3.1.2 E glutamine synthetase
NDMLAEPG_01357 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NDMLAEPG_01358 2.7e-48 S Domain of unknown function (DUF956)
NDMLAEPG_01359 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NDMLAEPG_01360 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NDMLAEPG_01361 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NDMLAEPG_01362 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
NDMLAEPG_01363 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NDMLAEPG_01364 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NDMLAEPG_01365 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NDMLAEPG_01366 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
NDMLAEPG_01367 4.8e-170 nusA K Participates in both transcription termination and antitermination
NDMLAEPG_01368 1.4e-39 ylxR K Protein of unknown function (DUF448)
NDMLAEPG_01369 6.9e-26 ylxQ J ribosomal protein
NDMLAEPG_01370 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NDMLAEPG_01371 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NDMLAEPG_01372 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NDMLAEPG_01373 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NDMLAEPG_01374 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NDMLAEPG_01375 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NDMLAEPG_01376 1.5e-274 dnaK O Heat shock 70 kDa protein
NDMLAEPG_01377 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NDMLAEPG_01378 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NDMLAEPG_01380 9.2e-206 glnP P ABC transporter
NDMLAEPG_01381 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NDMLAEPG_01382 1.5e-31
NDMLAEPG_01383 2e-111 ampC V Beta-lactamase
NDMLAEPG_01384 3.5e-110 cobQ S glutamine amidotransferase
NDMLAEPG_01385 6.1e-220 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NDMLAEPG_01386 6.8e-86 tdk 2.7.1.21 F thymidine kinase
NDMLAEPG_01387 2.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NDMLAEPG_01388 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NDMLAEPG_01389 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NDMLAEPG_01390 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NDMLAEPG_01391 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
NDMLAEPG_01392 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NDMLAEPG_01393 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NDMLAEPG_01394 2.7e-57 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NDMLAEPG_01395 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NDMLAEPG_01396 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NDMLAEPG_01397 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NDMLAEPG_01398 3.9e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NDMLAEPG_01399 4.1e-15 ywzB S Protein of unknown function (DUF1146)
NDMLAEPG_01400 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NDMLAEPG_01401 5.4e-92 sip L Belongs to the 'phage' integrase family
NDMLAEPG_01402 3e-15 S Hypothetical protein (DUF2513)
NDMLAEPG_01404 2.3e-17 E Zn peptidase
NDMLAEPG_01405 4.3e-29 S sequence-specific DNA binding
NDMLAEPG_01407 7.2e-49 L Psort location Cytoplasmic, score
NDMLAEPG_01411 2.9e-17 K Cro/C1-type HTH DNA-binding domain
NDMLAEPG_01412 2.2e-46 S DNA binding
NDMLAEPG_01413 6.3e-18
NDMLAEPG_01417 2.9e-75 recT L RecT family
NDMLAEPG_01418 2.4e-86 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NDMLAEPG_01420 2e-19
NDMLAEPG_01421 7.4e-24 L Psort location Cytoplasmic, score
NDMLAEPG_01422 4.1e-30 dnaC L IstB-like ATP binding protein
NDMLAEPG_01424 1e-24 S sequence-specific DNA binding
NDMLAEPG_01426 3.4e-31 rusA L Endodeoxyribonuclease RusA
NDMLAEPG_01427 3.7e-105 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NDMLAEPG_01436 7e-32 arpU S Phage transcriptional regulator, ArpU family
NDMLAEPG_01437 1.6e-43 2.1.1.72 KL DNA methylase
NDMLAEPG_01438 6.9e-71 S ATPase activity
NDMLAEPG_01440 1.9e-41 L transposase activity
NDMLAEPG_01441 7.7e-132 ps334 S Terminase-like family
NDMLAEPG_01442 2.5e-162 S Phage portal protein, SPP1 Gp6-like
NDMLAEPG_01443 2.8e-59 S Phage Mu protein F like protein
NDMLAEPG_01444 5.7e-13 S Domain of unknown function (DUF4355)
NDMLAEPG_01445 4.3e-104 gpG
NDMLAEPG_01446 3.2e-35 S Phage gp6-like head-tail connector protein
NDMLAEPG_01447 4.2e-10
NDMLAEPG_01448 1.6e-32
NDMLAEPG_01449 1.8e-18
NDMLAEPG_01450 6.1e-48
NDMLAEPG_01451 8.1e-15 S Phage tail assembly chaperone protein, TAC
NDMLAEPG_01453 2.4e-95 D NLP P60 protein
NDMLAEPG_01454 1e-77 S Phage tail protein
NDMLAEPG_01455 3.4e-79 M Prophage endopeptidase tail
NDMLAEPG_01456 3.2e-99 M Prophage endopeptidase tail
NDMLAEPG_01458 1e-25 S Calcineurin-like phosphoesterase
NDMLAEPG_01461 1.7e-30 L DNA replication protein
NDMLAEPG_01462 1.7e-133 S D5 N terminal like
NDMLAEPG_01464 3.8e-52 nmtR K Transcriptional regulator
NDMLAEPG_01465 1.7e-263 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
NDMLAEPG_01466 1.4e-24 K Cro/C1-type HTH DNA-binding domain
NDMLAEPG_01467 2.4e-08 S Helix-turn-helix domain
NDMLAEPG_01469 6.8e-39 K COG3617 Prophage antirepressor
NDMLAEPG_01470 3.9e-16 K Transcriptional regulator, Cro CI family
NDMLAEPG_01471 1.1e-07 K Helix-turn-helix XRE-family like proteins
NDMLAEPG_01472 1.2e-16 K Phage regulatory protein Rha (Phage_pRha)
NDMLAEPG_01474 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
NDMLAEPG_01475 6.7e-114 L Transposase IS66 family
NDMLAEPG_01476 2.9e-93 yihY S Belongs to the UPF0761 family
NDMLAEPG_01477 2.8e-12 mltD CBM50 M Lysin motif
NDMLAEPG_01482 6.7e-15
NDMLAEPG_01484 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NDMLAEPG_01485 1.3e-212 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NDMLAEPG_01486 8.1e-280 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NDMLAEPG_01487 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NDMLAEPG_01488 3.3e-117 EGP Major Facilitator Superfamily
NDMLAEPG_01489 1.1e-124 akr5f 1.1.1.346 S reductase
NDMLAEPG_01490 2.7e-72 K Transcriptional regulator
NDMLAEPG_01491 9.9e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
NDMLAEPG_01492 9.7e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NDMLAEPG_01493 4.7e-67 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
NDMLAEPG_01494 7e-68 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
NDMLAEPG_01495 1.6e-131 L Belongs to the 'phage' integrase family
NDMLAEPG_01496 3.1e-130 3.1.21.3 V Type I restriction modification DNA specificity domain
NDMLAEPG_01497 5.2e-202 hsdM 2.1.1.72 V type I restriction-modification system
NDMLAEPG_01498 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NDMLAEPG_01500 4.9e-22 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
NDMLAEPG_01501 2.8e-56 3.6.1.27 I Acid phosphatase homologues
NDMLAEPG_01502 2.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
NDMLAEPG_01503 4.4e-74 2.3.1.178 M GNAT acetyltransferase
NDMLAEPG_01505 1e-195 ade 3.5.4.2 F Adenine deaminase C-terminal domain
NDMLAEPG_01506 1e-64 ypsA S Belongs to the UPF0398 family
NDMLAEPG_01507 4.4e-189 nhaC C Na H antiporter NhaC
NDMLAEPG_01508 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NDMLAEPG_01509 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NDMLAEPG_01510 7.3e-113 xerD D recombinase XerD
NDMLAEPG_01511 4.8e-125 cvfB S S1 domain
NDMLAEPG_01512 4.1e-51 yeaL S Protein of unknown function (DUF441)
NDMLAEPG_01513 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NDMLAEPG_01514 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NDMLAEPG_01515 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NDMLAEPG_01516 4.5e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NDMLAEPG_01517 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NDMLAEPG_01518 5.9e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NDMLAEPG_01519 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NDMLAEPG_01520 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
NDMLAEPG_01521 1.3e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NDMLAEPG_01522 1.2e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NDMLAEPG_01523 9.7e-73
NDMLAEPG_01526 4.7e-09 M LysM domain
NDMLAEPG_01527 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NDMLAEPG_01528 1e-27 ysxB J Cysteine protease Prp
NDMLAEPG_01529 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
NDMLAEPG_01532 2.2e-08 S Protein of unknown function (DUF2922)
NDMLAEPG_01534 1.3e-16 K DNA-templated transcription, initiation
NDMLAEPG_01536 1.2e-65 H Methyltransferase domain
NDMLAEPG_01537 3.8e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
NDMLAEPG_01538 2.5e-41 wecD M Acetyltransferase (GNAT) family
NDMLAEPG_01540 1.4e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
NDMLAEPG_01541 4.4e-41 S Protein of unknown function (DUF1211)
NDMLAEPG_01543 5e-86 1.1.1.1 C Zinc-binding dehydrogenase
NDMLAEPG_01544 4.5e-30 S CHY zinc finger
NDMLAEPG_01545 2.1e-39 K Transcriptional regulator
NDMLAEPG_01546 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
NDMLAEPG_01549 5.6e-126 M Glycosyl transferases group 1
NDMLAEPG_01550 3.4e-64 M Glycosyl transferases group 1
NDMLAEPG_01551 3.7e-179 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NDMLAEPG_01552 2.1e-146 lspL 5.1.3.6 GM RmlD substrate binding domain
NDMLAEPG_01553 2.2e-104 cps2I S Psort location CytoplasmicMembrane, score
NDMLAEPG_01554 3.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
NDMLAEPG_01555 2.3e-116 S Glycosyltransferase WbsX
NDMLAEPG_01556 2.7e-52
NDMLAEPG_01558 2.5e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
NDMLAEPG_01559 1e-42 GT2 V Glycosyl transferase, family 2
NDMLAEPG_01560 1.5e-75 M Glycosyltransferase Family 4
NDMLAEPG_01561 1.8e-79 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
NDMLAEPG_01562 5.3e-121 2.4.1.52 GT4 M Glycosyl transferases group 1
NDMLAEPG_01563 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
NDMLAEPG_01564 4.8e-77 epsL M Bacterial sugar transferase
NDMLAEPG_01565 9.1e-167 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
NDMLAEPG_01566 1.2e-221 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
NDMLAEPG_01567 9.4e-65 cpsD D AAA domain
NDMLAEPG_01568 1.4e-48 cps4C M Chain length determinant protein
NDMLAEPG_01569 6.7e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NDMLAEPG_01570 2e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NDMLAEPG_01571 4.8e-81
NDMLAEPG_01572 6e-79 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NDMLAEPG_01573 2.3e-113 yitU 3.1.3.104 S hydrolase
NDMLAEPG_01574 4.5e-60 speG J Acetyltransferase (GNAT) domain
NDMLAEPG_01575 2e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NDMLAEPG_01576 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NDMLAEPG_01577 1.3e-204 pipD E Dipeptidase
NDMLAEPG_01578 2.3e-45
NDMLAEPG_01579 3.5e-64 K helix_turn_helix, arabinose operon control protein
NDMLAEPG_01580 8.9e-54 S Membrane
NDMLAEPG_01581 0.0 rafA 3.2.1.22 G alpha-galactosidase
NDMLAEPG_01582 6.9e-309 L Helicase C-terminal domain protein
NDMLAEPG_01583 1.9e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
NDMLAEPG_01584 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NDMLAEPG_01585 2.4e-113 2.7.7.65 T diguanylate cyclase activity
NDMLAEPG_01586 0.0 ydaN S Bacterial cellulose synthase subunit
NDMLAEPG_01587 1.2e-201 ydaM M Glycosyl transferase family group 2
NDMLAEPG_01588 5.3e-159 S Protein conserved in bacteria
NDMLAEPG_01589 2.4e-36 S Protein conserved in bacteria
NDMLAEPG_01590 6.5e-183
NDMLAEPG_01591 1.7e-129 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
NDMLAEPG_01592 2.4e-32 2.7.7.65 T GGDEF domain
NDMLAEPG_01594 1.5e-146 pbuO_1 S Permease family
NDMLAEPG_01595 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
NDMLAEPG_01596 1.5e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NDMLAEPG_01597 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NDMLAEPG_01598 3.6e-220 cydD CO ABC transporter transmembrane region
NDMLAEPG_01599 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NDMLAEPG_01600 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NDMLAEPG_01601 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
NDMLAEPG_01602 7e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
NDMLAEPG_01603 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
NDMLAEPG_01604 5e-19 glpE P Rhodanese Homology Domain
NDMLAEPG_01605 2.9e-61 L Transposase
NDMLAEPG_01606 1.9e-46 L Transposase
NDMLAEPG_01607 5.8e-171 L Integrase core domain
NDMLAEPG_01608 1.2e-123 sip L Belongs to the 'phage' integrase family
NDMLAEPG_01609 5.5e-105 tra L Transposase and inactivated derivatives, IS30 family
NDMLAEPG_01617 9.1e-67 1.5.1.38 S NADPH-dependent FMN reductase
NDMLAEPG_01618 5.8e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NDMLAEPG_01619 3.9e-76 L haloacid dehalogenase-like hydrolase
NDMLAEPG_01620 4e-61 EG EamA-like transporter family
NDMLAEPG_01621 5.3e-118 K AI-2E family transporter
NDMLAEPG_01622 1.3e-173 malY 4.4.1.8 E Aminotransferase, class I
NDMLAEPG_01623 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NDMLAEPG_01624 6.2e-43 S virion core protein, lumpy skin disease virus
NDMLAEPG_01628 3.9e-10
NDMLAEPG_01629 3.8e-99 V domain protein
NDMLAEPG_01630 1.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
NDMLAEPG_01631 1.6e-17
NDMLAEPG_01632 1.1e-104 azlC E AzlC protein
NDMLAEPG_01633 1.3e-38 azlD S branched-chain amino acid
NDMLAEPG_01634 2.4e-65 I alpha/beta hydrolase fold
NDMLAEPG_01635 3.1e-25
NDMLAEPG_01636 1.2e-58 3.6.1.27 I phosphatase
NDMLAEPG_01637 5.4e-23
NDMLAEPG_01638 2.9e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NDMLAEPG_01639 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
NDMLAEPG_01640 3.1e-27 cspC K Cold shock protein
NDMLAEPG_01641 9.9e-37 thrE S Putative threonine/serine exporter
NDMLAEPG_01642 3e-33 thrE S Putative threonine/serine exporter
NDMLAEPG_01643 2.8e-49 S Threonine/Serine exporter, ThrE
NDMLAEPG_01644 3.2e-121 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NDMLAEPG_01645 4.9e-87 S Sucrose-6F-phosphate phosphohydrolase
NDMLAEPG_01646 1.9e-34 trxA O Belongs to the thioredoxin family
NDMLAEPG_01647 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NDMLAEPG_01648 2e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NDMLAEPG_01649 7.3e-65 degV S Uncharacterised protein, DegV family COG1307
NDMLAEPG_01651 4.3e-54 queT S QueT transporter
NDMLAEPG_01652 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
NDMLAEPG_01653 5e-102 IQ Enoyl-(Acyl carrier protein) reductase
NDMLAEPG_01654 4.6e-112 argE 3.5.1.18 E Peptidase dimerisation domain
NDMLAEPG_01655 2.5e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NDMLAEPG_01656 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NDMLAEPG_01657 5e-87 S Alpha beta hydrolase
NDMLAEPG_01658 1.6e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NDMLAEPG_01659 3.6e-140 V MatE
NDMLAEPG_01660 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
NDMLAEPG_01661 2.2e-63 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDMLAEPG_01662 9.6e-97 V ABC transporter
NDMLAEPG_01663 9.6e-132 bacI V MacB-like periplasmic core domain
NDMLAEPG_01664 3.7e-75 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NDMLAEPG_01665 4.8e-26
NDMLAEPG_01666 2.1e-180 yhdP S Transporter associated domain
NDMLAEPG_01667 2.7e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
NDMLAEPG_01668 0.0 L Helicase C-terminal domain protein
NDMLAEPG_01669 2.1e-250 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NDMLAEPG_01670 6.3e-212 yfnA E Amino Acid
NDMLAEPG_01671 5.4e-53 zur P Belongs to the Fur family
NDMLAEPG_01672 3e-12 3.2.1.14 GH18
NDMLAEPG_01673 5e-98
NDMLAEPG_01674 1.3e-09
NDMLAEPG_01675 3.7e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NDMLAEPG_01676 1.9e-99 glnH ET ABC transporter
NDMLAEPG_01677 1.2e-85 gluC P ABC transporter permease
NDMLAEPG_01678 9.6e-78 glnP P ABC transporter permease
NDMLAEPG_01679 9e-184 steT E amino acid
NDMLAEPG_01680 6.5e-21 K Acetyltransferase (GNAT) domain
NDMLAEPG_01681 3.2e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
NDMLAEPG_01682 2.6e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NDMLAEPG_01683 2.5e-78 K rpiR family
NDMLAEPG_01684 4.3e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NDMLAEPG_01685 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NDMLAEPG_01686 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NDMLAEPG_01687 1e-100 rplD J Forms part of the polypeptide exit tunnel
NDMLAEPG_01688 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NDMLAEPG_01689 4.1e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NDMLAEPG_01690 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NDMLAEPG_01691 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NDMLAEPG_01692 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NDMLAEPG_01693 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NDMLAEPG_01694 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
NDMLAEPG_01695 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NDMLAEPG_01696 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NDMLAEPG_01697 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NDMLAEPG_01698 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NDMLAEPG_01699 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NDMLAEPG_01700 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NDMLAEPG_01701 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NDMLAEPG_01702 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NDMLAEPG_01703 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NDMLAEPG_01704 2.1e-22 rpmD J Ribosomal protein L30
NDMLAEPG_01705 1e-67 rplO J Binds to the 23S rRNA
NDMLAEPG_01706 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NDMLAEPG_01707 3.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NDMLAEPG_01708 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NDMLAEPG_01709 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NDMLAEPG_01710 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NDMLAEPG_01711 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NDMLAEPG_01712 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NDMLAEPG_01713 4.8e-53 rplQ J Ribosomal protein L17
NDMLAEPG_01714 1.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NDMLAEPG_01715 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NDMLAEPG_01716 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NDMLAEPG_01717 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NDMLAEPG_01718 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NDMLAEPG_01719 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
NDMLAEPG_01720 5.7e-28
NDMLAEPG_01721 3.1e-246 yjbQ P TrkA C-terminal domain protein
NDMLAEPG_01722 0.0 helD 3.6.4.12 L DNA helicase
NDMLAEPG_01723 4e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NDMLAEPG_01724 2e-109 hrtB V ABC transporter permease
NDMLAEPG_01725 4.2e-33 ygfC K transcriptional regulator (TetR family)
NDMLAEPG_01726 1.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NDMLAEPG_01727 5.6e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NDMLAEPG_01728 6.8e-35 M LysM domain protein
NDMLAEPG_01729 9.8e-115 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NDMLAEPG_01730 7.9e-106 sbcC L Putative exonuclease SbcCD, C subunit
NDMLAEPG_01731 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
NDMLAEPG_01732 7.2e-53 perR P Belongs to the Fur family
NDMLAEPG_01733 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NDMLAEPG_01734 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NDMLAEPG_01735 2.5e-86 S (CBS) domain
NDMLAEPG_01736 1.8e-157 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NDMLAEPG_01737 2.2e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NDMLAEPG_01738 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NDMLAEPG_01739 1.2e-139 yabM S Polysaccharide biosynthesis protein
NDMLAEPG_01740 3.6e-31 yabO J S4 domain protein
NDMLAEPG_01741 1e-21 divIC D Septum formation initiator
NDMLAEPG_01742 1.1e-40 yabR J RNA binding
NDMLAEPG_01743 1.9e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NDMLAEPG_01744 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NDMLAEPG_01745 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDMLAEPG_01746 7.8e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NDMLAEPG_01747 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDMLAEPG_01748 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NDMLAEPG_01756 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NDMLAEPG_01757 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
NDMLAEPG_01758 5.1e-54 fld C Flavodoxin
NDMLAEPG_01759 8.7e-53 gtcA S Teichoic acid glycosylation protein
NDMLAEPG_01760 0.0 S Bacterial membrane protein YfhO
NDMLAEPG_01761 4.4e-119 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
NDMLAEPG_01762 1.7e-122 S Sulfite exporter TauE/SafE
NDMLAEPG_01763 1.1e-70 K Sugar-specific transcriptional regulator TrmB
NDMLAEPG_01764 3.5e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NDMLAEPG_01765 3.5e-182 pepS E Thermophilic metalloprotease (M29)
NDMLAEPG_01766 1.9e-226 E Amino acid permease
NDMLAEPG_01767 4.9e-85 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NDMLAEPG_01768 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NDMLAEPG_01769 2.9e-78 galM 5.1.3.3 G Aldose 1-epimerase
NDMLAEPG_01770 4.3e-213 malT G Transporter, major facilitator family protein
NDMLAEPG_01771 4.2e-101 malR K Transcriptional regulator, LacI family
NDMLAEPG_01772 2.3e-279 kup P Transport of potassium into the cell
NDMLAEPG_01774 2e-20 S Domain of unknown function (DUF3284)
NDMLAEPG_01775 5.2e-160 yfmL L DEAD DEAH box helicase
NDMLAEPG_01776 7e-128 mocA S Oxidoreductase
NDMLAEPG_01777 2e-24 S Domain of unknown function (DUF4828)
NDMLAEPG_01778 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
NDMLAEPG_01779 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NDMLAEPG_01780 1.4e-193 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
NDMLAEPG_01781 1.4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
NDMLAEPG_01782 4.2e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NDMLAEPG_01783 1.4e-265 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NDMLAEPG_01784 3.6e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NDMLAEPG_01785 4.9e-42 O ADP-ribosylglycohydrolase
NDMLAEPG_01786 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
NDMLAEPG_01787 6.4e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NDMLAEPG_01788 9.7e-35 K GNAT family
NDMLAEPG_01789 1.7e-40
NDMLAEPG_01791 1.6e-159 mgtE P Acts as a magnesium transporter
NDMLAEPG_01792 7.6e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NDMLAEPG_01793 1.3e-116 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NDMLAEPG_01794 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
NDMLAEPG_01795 9e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NDMLAEPG_01796 1.7e-35 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NDMLAEPG_01797 6.3e-193 pbuX F xanthine permease
NDMLAEPG_01798 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NDMLAEPG_01799 1.6e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
NDMLAEPG_01800 5.5e-64 S ECF transporter, substrate-specific component
NDMLAEPG_01801 1.7e-126 mleP S Sodium Bile acid symporter family
NDMLAEPG_01802 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NDMLAEPG_01803 1.8e-71 mleR K LysR family
NDMLAEPG_01804 1.1e-56 K transcriptional
NDMLAEPG_01805 5.9e-41 K Bacterial regulatory proteins, tetR family
NDMLAEPG_01806 4e-59 T Belongs to the universal stress protein A family
NDMLAEPG_01807 8.1e-44 K Copper transport repressor CopY TcrY
NDMLAEPG_01808 2.1e-116 3.2.1.18 GH33 M Rib/alpha-like repeat
NDMLAEPG_01809 1.4e-113 3.2.1.18 GH33 M Rib/alpha-like repeat
NDMLAEPG_01811 1.9e-95 ypuA S Protein of unknown function (DUF1002)
NDMLAEPG_01812 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
NDMLAEPG_01813 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NDMLAEPG_01814 4.6e-36 yncA 2.3.1.79 S Maltose acetyltransferase
NDMLAEPG_01815 5.3e-206 yflS P Sodium:sulfate symporter transmembrane region
NDMLAEPG_01816 7.2e-200 frdC 1.3.5.4 C FAD binding domain
NDMLAEPG_01817 3.9e-238 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NDMLAEPG_01818 2e-14 ybaN S Protein of unknown function (DUF454)
NDMLAEPG_01819 8.2e-177 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NDMLAEPG_01820 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NDMLAEPG_01821 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NDMLAEPG_01822 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NDMLAEPG_01823 5.1e-72 ywlG S Belongs to the UPF0340 family
NDMLAEPG_01824 5.2e-65 S Acetyltransferase (GNAT) domain
NDMLAEPG_01826 3.5e-50 K Cro/C1-type HTH DNA-binding domain
NDMLAEPG_01827 1.6e-174 spoVK O ATPase family associated with various cellular activities (AAA)
NDMLAEPG_01830 8.3e-126 S Bacteriophage abortive infection AbiH
NDMLAEPG_01831 4.5e-86 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
NDMLAEPG_01832 3.2e-37 hsdM 2.1.1.72 V type I restriction-modification system
NDMLAEPG_01833 1.3e-162 hsdM 2.1.1.72 V cog cog0286
NDMLAEPG_01834 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NDMLAEPG_01835 5.4e-19 K Cro/C1-type HTH DNA-binding domain
NDMLAEPG_01836 9.1e-78 L AAA domain
NDMLAEPG_01837 4.1e-16
NDMLAEPG_01838 3.9e-22
NDMLAEPG_01839 1.3e-75 K phage regulatory protein, rha family
NDMLAEPG_01840 1.3e-17
NDMLAEPG_01841 1.4e-121 L Mrr N-terminal domain
NDMLAEPG_01842 9.9e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NDMLAEPG_01843 9.8e-146 yegS 2.7.1.107 G Lipid kinase
NDMLAEPG_01844 2.8e-255 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NDMLAEPG_01845 4e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NDMLAEPG_01846 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NDMLAEPG_01847 9.3e-161 camS S sex pheromone
NDMLAEPG_01848 1.3e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NDMLAEPG_01849 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NDMLAEPG_01850 4.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NDMLAEPG_01854 1.7e-147 scrR K helix_turn _helix lactose operon repressor
NDMLAEPG_01855 1.8e-217 scrB 3.2.1.26 GH32 G invertase
NDMLAEPG_01856 6.1e-282 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
NDMLAEPG_01857 2e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NDMLAEPG_01858 2.1e-114 ntpJ P Potassium uptake protein
NDMLAEPG_01859 2.2e-58 ktrA P TrkA-N domain
NDMLAEPG_01860 5.7e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NDMLAEPG_01861 1.1e-43 K helix_turn_helix isocitrate lyase regulation
NDMLAEPG_01862 5.3e-120 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDMLAEPG_01863 1.4e-102 pfoS S Phosphotransferase system, EIIC
NDMLAEPG_01864 1.4e-19
NDMLAEPG_01865 2e-93 S Predicted membrane protein (DUF2207)
NDMLAEPG_01866 1.2e-54 bioY S BioY family
NDMLAEPG_01867 5.7e-184 lmrB EGP Major facilitator Superfamily
NDMLAEPG_01868 2.5e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NDMLAEPG_01869 7.6e-74 glcR K DeoR C terminal sensor domain
NDMLAEPG_01870 1e-60 yceE S haloacid dehalogenase-like hydrolase
NDMLAEPG_01871 1.9e-41 S CAAX protease self-immunity
NDMLAEPG_01872 1.2e-33 S Domain of unknown function (DUF4811)
NDMLAEPG_01873 6.1e-197 lmrB EGP Major facilitator Superfamily
NDMLAEPG_01874 4.2e-32 merR K MerR HTH family regulatory protein
NDMLAEPG_01875 1.8e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NDMLAEPG_01876 9.1e-71 S Protein of unknown function (DUF554)
NDMLAEPG_01877 6.9e-120 G Bacterial extracellular solute-binding protein
NDMLAEPG_01878 3e-79 baeR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NDMLAEPG_01879 1.6e-100 baeS T Histidine kinase
NDMLAEPG_01880 7e-80 rbsB G sugar-binding domain protein
NDMLAEPG_01881 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NDMLAEPG_01882 8e-119 manY G PTS system sorbose-specific iic component
NDMLAEPG_01883 2.1e-147 manN G system, mannose fructose sorbose family IID component
NDMLAEPG_01884 3.2e-52 manO S Domain of unknown function (DUF956)
NDMLAEPG_01885 2.1e-70 mltD CBM50 M NlpC P60 family protein
NDMLAEPG_01886 4.7e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NDMLAEPG_01887 1.6e-163 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDMLAEPG_01888 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
NDMLAEPG_01889 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NDMLAEPG_01890 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NDMLAEPG_01891 3e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NDMLAEPG_01892 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NDMLAEPG_01893 2e-46 S CRISPR-associated protein (Cas_Csn2)
NDMLAEPG_01894 7.8e-38 K transcriptional regulator PadR family
NDMLAEPG_01895 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
NDMLAEPG_01896 1.2e-15 S Putative adhesin
NDMLAEPG_01897 2.2e-16 pspC KT PspC domain
NDMLAEPG_01899 5.1e-13 S Enterocin A Immunity
NDMLAEPG_01900 4e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NDMLAEPG_01901 1.3e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
NDMLAEPG_01902 4.3e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NDMLAEPG_01903 1.1e-166 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NDMLAEPG_01904 1.5e-120 potB P ABC transporter permease
NDMLAEPG_01905 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
NDMLAEPG_01906 1.3e-159 potD P ABC transporter
NDMLAEPG_01907 3.5e-132 ABC-SBP S ABC transporter
NDMLAEPG_01908 3.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NDMLAEPG_01909 6.7e-107 XK27_08845 S ABC transporter, ATP-binding protein
NDMLAEPG_01910 2.8e-66 M ErfK YbiS YcfS YnhG
NDMLAEPG_01911 1.2e-53 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NDMLAEPG_01912 4.2e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NDMLAEPG_01913 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NDMLAEPG_01914 1.2e-102 pgm3 G phosphoglycerate mutase
NDMLAEPG_01915 4.7e-56 S CAAX protease self-immunity
NDMLAEPG_01916 2.2e-47 C Flavodoxin
NDMLAEPG_01917 9.7e-60 yphH S Cupin domain
NDMLAEPG_01918 3.6e-46 yphJ 4.1.1.44 S decarboxylase
NDMLAEPG_01919 2.9e-143 E methionine synthase, vitamin-B12 independent
NDMLAEPG_01920 7.4e-107 metQ1 P Belongs to the nlpA lipoprotein family
NDMLAEPG_01921 1.5e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NDMLAEPG_01922 2.7e-70 metI P ABC transporter permease
NDMLAEPG_01923 4.4e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NDMLAEPG_01924 3e-84 drgA C nitroreductase
NDMLAEPG_01925 2.5e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
NDMLAEPG_01926 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NDMLAEPG_01927 8.1e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NDMLAEPG_01928 4.8e-264 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NDMLAEPG_01930 2.3e-150 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NDMLAEPG_01931 2.4e-31 metI U ABC transporter permease
NDMLAEPG_01932 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
NDMLAEPG_01933 1.8e-53 S Protein of unknown function (DUF4256)
NDMLAEPG_01936 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NDMLAEPG_01937 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NDMLAEPG_01938 2.6e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NDMLAEPG_01939 4e-230 lpdA 1.8.1.4 C Dehydrogenase
NDMLAEPG_01940 2.1e-148 lplA 6.3.1.20 H Lipoate-protein ligase
NDMLAEPG_01941 9.2e-56 S Protein of unknown function (DUF975)
NDMLAEPG_01942 5.7e-78 E GDSL-like Lipase/Acylhydrolase family
NDMLAEPG_01943 1.4e-38
NDMLAEPG_01944 4.1e-27 gcvR T Belongs to the UPF0237 family
NDMLAEPG_01945 2.1e-220 XK27_08635 S UPF0210 protein
NDMLAEPG_01946 4.5e-87 fruR K DeoR C terminal sensor domain
NDMLAEPG_01947 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NDMLAEPG_01948 7.3e-129 fruA 2.7.1.202 GT Phosphotransferase System
NDMLAEPG_01949 1.3e-143 fruA 2.7.1.202 GT Phosphotransferase System
NDMLAEPG_01950 5.5e-144 dapE 3.5.1.18 E Peptidase dimerisation domain
NDMLAEPG_01951 1e-149 E glutamate:sodium symporter activity
NDMLAEPG_01952 1.2e-145 Q Imidazolonepropionase and related amidohydrolases
NDMLAEPG_01953 4.1e-62 yphA GM NAD dependent epimerase/dehydratase family
NDMLAEPG_01954 3e-76 K Helix-turn-helix domain, rpiR family
NDMLAEPG_01955 1.2e-91 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NDMLAEPG_01956 1.1e-126 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NDMLAEPG_01957 1.2e-91 nanK GK ROK family
NDMLAEPG_01958 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
NDMLAEPG_01959 4e-64 G Xylose isomerase domain protein TIM barrel
NDMLAEPG_01960 1.1e-153 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NDMLAEPG_01961 8.6e-207 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDMLAEPG_01962 8.5e-74 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NDMLAEPG_01963 1e-111 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NDMLAEPG_01964 3.5e-41 S Iron-sulfur cluster assembly protein
NDMLAEPG_01965 1.3e-66 S Protein of unknown function (DUF1440)
NDMLAEPG_01966 3.8e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NDMLAEPG_01967 1e-186 mtnE 2.6.1.83 E Aminotransferase
NDMLAEPG_01969 6e-15
NDMLAEPG_01970 1.3e-87 S Haloacid dehalogenase-like hydrolase
NDMLAEPG_01971 2.9e-38 blpT
NDMLAEPG_01972 6.6e-19
NDMLAEPG_01973 5.5e-08
NDMLAEPG_01975 1.2e-12
NDMLAEPG_01976 3.1e-16
NDMLAEPG_01980 1.5e-58 2.7.13.3 T GHKL domain
NDMLAEPG_01981 8.7e-57 K LytTr DNA-binding domain
NDMLAEPG_01989 2.6e-281 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NDMLAEPG_01990 5.8e-86 mesE M Transport protein ComB
NDMLAEPG_01993 6.4e-71 xerD L Phage integrase, N-terminal SAM-like domain
NDMLAEPG_01994 1.1e-265 fbp 3.1.3.11 G phosphatase activity
NDMLAEPG_01996 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NDMLAEPG_01997 9.3e-100 fabK 1.3.1.9 S Nitronate monooxygenase
NDMLAEPG_01998 2.1e-29 S Phage minor capsid protein 2
NDMLAEPG_02000 8.5e-14 S YjcQ protein
NDMLAEPG_02003 1.2e-21 M by MetaGeneAnnotator
NDMLAEPG_02004 4e-110 IQ NAD dependent epimerase/dehydratase family
NDMLAEPG_02005 7.6e-104 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
NDMLAEPG_02006 4.5e-43 gutM K Glucitol operon activator protein (GutM)
NDMLAEPG_02007 2.2e-83 srlA G PTS system enzyme II sorbitol-specific factor
NDMLAEPG_02008 1.2e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
NDMLAEPG_02009 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NDMLAEPG_02010 2.5e-65 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
NDMLAEPG_02011 4.2e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NDMLAEPG_02012 7.3e-136 pfoS S Phosphotransferase system, EIIC
NDMLAEPG_02013 9.7e-89 KT Transcriptional regulatory protein, C terminal
NDMLAEPG_02014 1.3e-105 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NDMLAEPG_02015 3.3e-73 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
NDMLAEPG_02016 1.2e-44 V ABC-2 family transporter protein
NDMLAEPG_02018 1.1e-27 K Helix-turn-helix XRE-family like proteins
NDMLAEPG_02019 9.5e-140 yfeO P Voltage gated chloride channel
NDMLAEPG_02020 7.6e-225 E ABC transporter, substratebinding protein
NDMLAEPG_02021 8.1e-116 sufC O FeS assembly ATPase SufC
NDMLAEPG_02022 3.3e-143 sufD O FeS assembly protein SufD
NDMLAEPG_02023 2.8e-147 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NDMLAEPG_02024 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
NDMLAEPG_02025 4.2e-240 sufB O assembly protein SufB
NDMLAEPG_02026 2.5e-45 S VIT family
NDMLAEPG_02027 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
NDMLAEPG_02028 7.6e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NDMLAEPG_02029 3.6e-112 rssA S Phospholipase, patatin family
NDMLAEPG_02030 8.2e-16
NDMLAEPG_02032 1.6e-87 S Fic/DOC family
NDMLAEPG_02033 3.5e-12 K Helix-turn-helix XRE-family like proteins
NDMLAEPG_02034 4.5e-10
NDMLAEPG_02035 5.3e-09 S Arc-like DNA binding domain
NDMLAEPG_02037 1.3e-20 S Replication initiator protein A (RepA) N-terminus
NDMLAEPG_02042 3.6e-07
NDMLAEPG_02044 1.4e-31 S Protein of unknown function (DUF3800)
NDMLAEPG_02051 5.1e-08
NDMLAEPG_02057 4.7e-07
NDMLAEPG_02058 3.9e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NDMLAEPG_02059 1.7e-54 rplI J Binds to the 23S rRNA
NDMLAEPG_02060 1.3e-204 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NDMLAEPG_02061 5.3e-64 C FMN binding
NDMLAEPG_02062 1.6e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NDMLAEPG_02064 8.7e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NDMLAEPG_02065 3.5e-59 ykhA 3.1.2.20 I Thioesterase superfamily
NDMLAEPG_02066 5.6e-10 S CAAX protease self-immunity
NDMLAEPG_02067 2.8e-81 S Belongs to the UPF0246 family
NDMLAEPG_02068 1.6e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NDMLAEPG_02069 9.3e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
NDMLAEPG_02070 3.7e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NDMLAEPG_02071 4.5e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NDMLAEPG_02072 3.8e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NDMLAEPG_02073 2.2e-56 3.1.3.48 K Transcriptional regulator
NDMLAEPG_02074 1.2e-197 1.3.5.4 C FMN_bind
NDMLAEPG_02075 1.6e-58 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
NDMLAEPG_02076 8.4e-49 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
NDMLAEPG_02077 2e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
NDMLAEPG_02078 2.8e-139 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NDMLAEPG_02079 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NDMLAEPG_02080 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
NDMLAEPG_02081 4.4e-101 G PTS system sorbose-specific iic component
NDMLAEPG_02082 2.4e-123 G PTS system mannose/fructose/sorbose family IID component
NDMLAEPG_02083 2e-39 2.7.1.191 G PTS system fructose IIA component
NDMLAEPG_02084 5.5e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
NDMLAEPG_02085 3.1e-112 lacI3 K helix_turn _helix lactose operon repressor
NDMLAEPG_02086 2.8e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NDMLAEPG_02087 5e-77 hchA S intracellular protease amidase
NDMLAEPG_02088 1.2e-21 K transcriptional regulator
NDMLAEPG_02089 5.6e-150 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NDMLAEPG_02090 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NDMLAEPG_02091 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NDMLAEPG_02092 1.5e-251 ctpA 3.6.3.54 P P-type ATPase
NDMLAEPG_02093 5e-66 pgm3 G phosphoglycerate mutase family
NDMLAEPG_02094 8.2e-55 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
NDMLAEPG_02095 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NDMLAEPG_02096 9.1e-219 yifK E Amino acid permease
NDMLAEPG_02097 6.9e-202 oppA E ABC transporter, substratebinding protein
NDMLAEPG_02098 1e-141 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NDMLAEPG_02099 5.8e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NDMLAEPG_02100 1.3e-180 oppD P Belongs to the ABC transporter superfamily
NDMLAEPG_02101 3.7e-155 oppF P Belongs to the ABC transporter superfamily
NDMLAEPG_02102 1.2e-15 psiE S Phosphate-starvation-inducible E
NDMLAEPG_02103 2.2e-209 mmuP E amino acid
NDMLAEPG_02104 7.6e-113 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NDMLAEPG_02105 4.5e-39 K LytTr DNA-binding domain
NDMLAEPG_02106 2.5e-16 S Protein of unknown function (DUF3021)
NDMLAEPG_02107 1.3e-150 yfeX P Peroxidase
NDMLAEPG_02108 1.8e-30 tetR K Transcriptional regulator C-terminal region
NDMLAEPG_02109 3.1e-47 S Short repeat of unknown function (DUF308)
NDMLAEPG_02110 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NDMLAEPG_02111 8.1e-163 oxlT P Major Facilitator Superfamily
NDMLAEPG_02112 5.8e-67 ybbL S ABC transporter
NDMLAEPG_02113 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
NDMLAEPG_02114 4.2e-43 ytcD K HxlR-like helix-turn-helix
NDMLAEPG_02115 6.9e-121 ytbE S reductase
NDMLAEPG_02116 7.5e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NDMLAEPG_02118 6.4e-96 XK27_06785 V ABC transporter, ATP-binding protein
NDMLAEPG_02119 1.1e-43 XK27_06780 V ABC transporter permease
NDMLAEPG_02120 8.2e-203 XK27_06780 V ABC transporter permease
NDMLAEPG_02122 5.1e-42 wecD K Acetyltransferase GNAT Family
NDMLAEPG_02123 3.9e-47 hmpT S ECF-type riboflavin transporter, S component
NDMLAEPG_02124 2.1e-69 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NDMLAEPG_02125 1.7e-09 yvaZ S Protein of unknown function (DUF1648)
NDMLAEPG_02126 1.7e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
NDMLAEPG_02127 7.6e-285 pepO 3.4.24.71 O Peptidase family M13
NDMLAEPG_02128 7.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
NDMLAEPG_02129 6.9e-54 K Transcriptional regulator C-terminal region

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)