ORF_ID e_value Gene_name EC_number CAZy COGs Description
HLOPPLNL_00002 2e-247 glnA 6.3.1.2 E glutamine synthetase
HLOPPLNL_00003 1.3e-45 glnR K Transcriptional regulator
HLOPPLNL_00004 3e-205 ynbB 4.4.1.1 P aluminum resistance
HLOPPLNL_00005 1.4e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLOPPLNL_00006 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
HLOPPLNL_00007 2.7e-46 yqhL P Rhodanese-like protein
HLOPPLNL_00008 4.7e-158 glk 2.7.1.2 G Glucokinase
HLOPPLNL_00009 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
HLOPPLNL_00010 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
HLOPPLNL_00011 8.7e-40 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLOPPLNL_00012 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HLOPPLNL_00013 1.3e-19 D nuclear chromosome segregation
HLOPPLNL_00014 5.5e-75 yciQ P membrane protein (DUF2207)
HLOPPLNL_00015 2.1e-43 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HLOPPLNL_00016 6.2e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
HLOPPLNL_00017 2.9e-26 yneF S UPF0154 protein
HLOPPLNL_00018 2.2e-30 ynzC S UPF0291 protein
HLOPPLNL_00019 2.5e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLOPPLNL_00020 1.9e-178 recN L May be involved in recombinational repair of damaged DNA
HLOPPLNL_00021 6.6e-49 argR K Regulates arginine biosynthesis genes
HLOPPLNL_00022 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HLOPPLNL_00023 6.1e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HLOPPLNL_00024 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLOPPLNL_00025 1.2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLOPPLNL_00026 1.7e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLOPPLNL_00027 1.9e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLOPPLNL_00028 3.7e-46 yqhY S Asp23 family, cell envelope-related function
HLOPPLNL_00029 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLOPPLNL_00030 2.2e-41 dut S dUTPase
HLOPPLNL_00031 5.5e-117
HLOPPLNL_00032 7.3e-105
HLOPPLNL_00033 1.2e-134 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HLOPPLNL_00034 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HLOPPLNL_00035 2.9e-120 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLOPPLNL_00036 3.9e-167 arlS 2.7.13.3 T Histidine kinase
HLOPPLNL_00037 4e-111 K response regulator
HLOPPLNL_00039 1.6e-108 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLOPPLNL_00040 2.7e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLOPPLNL_00041 6.4e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLOPPLNL_00042 3.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLOPPLNL_00043 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HLOPPLNL_00044 6.9e-37
HLOPPLNL_00045 1.8e-114 S N-acetylmuramoyl-L-alanine amidase activity
HLOPPLNL_00046 3.5e-21 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HLOPPLNL_00049 6.4e-35 cotH M CotH kinase protein
HLOPPLNL_00050 1.5e-47
HLOPPLNL_00051 3.5e-142 Z012_12235 S Baseplate J-like protein
HLOPPLNL_00052 2.7e-07
HLOPPLNL_00053 5.3e-35
HLOPPLNL_00054 8.1e-117
HLOPPLNL_00055 7.7e-44
HLOPPLNL_00056 1.3e-70 3.5.1.28 M LysM domain
HLOPPLNL_00057 1.4e-27 N phage tail tape measure protein
HLOPPLNL_00059 2.9e-17
HLOPPLNL_00060 9.1e-55
HLOPPLNL_00061 1.5e-109 Z012_02110 S Protein of unknown function (DUF3383)
HLOPPLNL_00062 4.2e-27
HLOPPLNL_00064 5.3e-48 Z012_02125
HLOPPLNL_00065 6.5e-25
HLOPPLNL_00066 8.8e-18 S LysM domain
HLOPPLNL_00067 1.9e-18
HLOPPLNL_00068 7.6e-108
HLOPPLNL_00069 6.3e-31 S Domain of unknown function (DUF4355)
HLOPPLNL_00072 7.6e-97
HLOPPLNL_00073 1e-188 S Phage portal protein, SPP1 Gp6-like
HLOPPLNL_00074 1.4e-210 S Terminase-like family
HLOPPLNL_00075 1e-51 ps333 L Terminase small subunit
HLOPPLNL_00078 1.5e-49 doc
HLOPPLNL_00079 1.9e-27 arpU S Phage transcriptional regulator, ArpU family
HLOPPLNL_00084 2.8e-21 S HNH endonuclease
HLOPPLNL_00085 1.1e-31 rusA L Endodeoxyribonuclease RusA
HLOPPLNL_00087 2.2e-19
HLOPPLNL_00088 2e-124 dnaB 3.6.4.12 L DnaB-like helicase C terminal domain
HLOPPLNL_00089 2.7e-35 L Helix-turn-helix domain
HLOPPLNL_00090 1.1e-92 S Putative HNHc nuclease
HLOPPLNL_00091 6.8e-33 S Protein of unknown function (DUF669)
HLOPPLNL_00092 2e-75 S AAA domain
HLOPPLNL_00093 1.7e-24 S Bacteriophage Mu Gam like protein
HLOPPLNL_00099 7e-56 kilA K BRO family, N-terminal domain
HLOPPLNL_00100 6.1e-12 cro K Helix-turn-helix XRE-family like proteins
HLOPPLNL_00102 8.5e-41 XK27_10050 K Peptidase S24-like
HLOPPLNL_00104 1.1e-33
HLOPPLNL_00105 3.7e-76 S Domain of unknown function DUF1829
HLOPPLNL_00106 8.2e-80 sip L Belongs to the 'phage' integrase family
HLOPPLNL_00107 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLOPPLNL_00108 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
HLOPPLNL_00109 1.5e-27 yazA L GIY-YIG catalytic domain protein
HLOPPLNL_00110 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
HLOPPLNL_00111 1.2e-88 plsC 2.3.1.51 I Acyltransferase
HLOPPLNL_00112 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HLOPPLNL_00113 7.8e-57 yceD S Uncharacterized ACR, COG1399
HLOPPLNL_00114 1.7e-122 ylbM S Belongs to the UPF0348 family
HLOPPLNL_00115 5.5e-82 H Nodulation protein S (NodS)
HLOPPLNL_00116 5.1e-49 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLOPPLNL_00117 6.7e-70 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HLOPPLNL_00118 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLOPPLNL_00119 6e-30 yhbY J RNA-binding protein
HLOPPLNL_00120 4.6e-181 yqeH S Ribosome biogenesis GTPase YqeH
HLOPPLNL_00121 1.6e-70 yqeG S HAD phosphatase, family IIIA
HLOPPLNL_00122 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLOPPLNL_00123 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HLOPPLNL_00124 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLOPPLNL_00125 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLOPPLNL_00126 3.3e-108 dnaI L Primosomal protein DnaI
HLOPPLNL_00127 1.2e-79 dnaB L replication initiation and membrane attachment
HLOPPLNL_00128 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLOPPLNL_00129 2.1e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLOPPLNL_00130 3.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLOPPLNL_00131 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLOPPLNL_00132 6.7e-69 ybhL S Belongs to the BI1 family
HLOPPLNL_00133 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
HLOPPLNL_00134 1.7e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HLOPPLNL_00135 2.6e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
HLOPPLNL_00136 8.9e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLOPPLNL_00137 9.8e-44 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HLOPPLNL_00138 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLOPPLNL_00139 9.1e-99 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HLOPPLNL_00140 8.4e-72 ecsB U ABC transporter
HLOPPLNL_00141 8.3e-94 ecsA V ABC transporter, ATP-binding protein
HLOPPLNL_00142 7e-53 hit FG histidine triad
HLOPPLNL_00144 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLOPPLNL_00145 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HLOPPLNL_00146 2e-21 yheA S Belongs to the UPF0342 family
HLOPPLNL_00147 8.6e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HLOPPLNL_00149 6.9e-87 ykuT M mechanosensitive ion channel
HLOPPLNL_00150 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLOPPLNL_00151 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLOPPLNL_00152 5.8e-45 ykuL S CBS domain
HLOPPLNL_00153 5.7e-119 gla U Major intrinsic protein
HLOPPLNL_00154 9.3e-303 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLOPPLNL_00155 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
HLOPPLNL_00156 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLOPPLNL_00157 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HLOPPLNL_00158 8.8e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HLOPPLNL_00159 3.6e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLOPPLNL_00160 5.5e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HLOPPLNL_00161 3.9e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLOPPLNL_00162 1.7e-46 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLOPPLNL_00163 8.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLOPPLNL_00164 1.1e-98 IQ reductase
HLOPPLNL_00165 5.5e-103 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HLOPPLNL_00166 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLOPPLNL_00167 2.4e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLOPPLNL_00168 4.2e-61 marR K Transcriptional regulator, MarR family
HLOPPLNL_00169 1.3e-65 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLOPPLNL_00170 3e-36
HLOPPLNL_00172 4.3e-182 S Protein of unknown function DUF262
HLOPPLNL_00173 1.5e-192 pepV 3.5.1.18 E dipeptidase PepV
HLOPPLNL_00174 8.3e-82 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLOPPLNL_00175 1.2e-62 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HLOPPLNL_00176 1.4e-186 ytgP S Polysaccharide biosynthesis protein
HLOPPLNL_00177 2.4e-192 cycA E Amino acid permease
HLOPPLNL_00178 2.1e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLOPPLNL_00179 2.5e-66 yrjD S LUD domain
HLOPPLNL_00180 3.6e-245 lutB C 4Fe-4S dicluster domain
HLOPPLNL_00181 6.9e-117 lutA C Cysteine-rich domain
HLOPPLNL_00182 7.4e-208 yfnA E Amino Acid
HLOPPLNL_00184 4.3e-61 uspA T universal stress protein
HLOPPLNL_00186 1.4e-12 yajC U Preprotein translocase
HLOPPLNL_00187 2.3e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLOPPLNL_00188 2.3e-182 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HLOPPLNL_00189 2.8e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLOPPLNL_00190 4.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLOPPLNL_00191 2.2e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLOPPLNL_00192 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLOPPLNL_00193 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
HLOPPLNL_00194 3.5e-160 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLOPPLNL_00195 4.7e-84 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLOPPLNL_00196 2.9e-64 ymfM S Helix-turn-helix domain
HLOPPLNL_00197 1.4e-90 IQ Enoyl-(Acyl carrier protein) reductase
HLOPPLNL_00198 9.3e-149 ymfH S Peptidase M16
HLOPPLNL_00199 9.1e-109 ymfF S Peptidase M16 inactive domain protein
HLOPPLNL_00200 3.5e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
HLOPPLNL_00201 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLOPPLNL_00202 4.4e-99 rrmA 2.1.1.187 H Methyltransferase
HLOPPLNL_00203 6.4e-61 ybaK J Aminoacyl-tRNA editing domain
HLOPPLNL_00204 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLOPPLNL_00205 1.4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLOPPLNL_00206 7.1e-21 cutC P Participates in the control of copper homeostasis
HLOPPLNL_00207 4e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HLOPPLNL_00208 2.2e-28 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HLOPPLNL_00209 5.7e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLOPPLNL_00210 5.3e-68 ybbR S YbbR-like protein
HLOPPLNL_00211 2.9e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLOPPLNL_00212 2.4e-71 S Protein of unknown function (DUF1361)
HLOPPLNL_00213 1.6e-115 murB 1.3.1.98 M Cell wall formation
HLOPPLNL_00214 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
HLOPPLNL_00215 3.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HLOPPLNL_00216 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HLOPPLNL_00217 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLOPPLNL_00218 2.4e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
HLOPPLNL_00219 3.1e-42 yxjI
HLOPPLNL_00220 1.5e-69 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HLOPPLNL_00221 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLOPPLNL_00222 2.8e-19 secG U Preprotein translocase
HLOPPLNL_00223 4.1e-180 clcA P chloride
HLOPPLNL_00224 3.5e-147 lmrP E Major Facilitator Superfamily
HLOPPLNL_00225 1.2e-168 T PhoQ Sensor
HLOPPLNL_00226 1.9e-103 K response regulator
HLOPPLNL_00227 7.2e-131 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLOPPLNL_00228 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLOPPLNL_00229 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLOPPLNL_00230 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HLOPPLNL_00231 2.9e-174 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLOPPLNL_00232 7.1e-136 cggR K Putative sugar-binding domain
HLOPPLNL_00234 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLOPPLNL_00235 1.8e-149 whiA K May be required for sporulation
HLOPPLNL_00236 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HLOPPLNL_00237 2.2e-125 rapZ S Displays ATPase and GTPase activities
HLOPPLNL_00238 1.9e-78 ylbE GM NAD dependent epimerase dehydratase family protein
HLOPPLNL_00239 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLOPPLNL_00240 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLOPPLNL_00241 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLOPPLNL_00242 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HLOPPLNL_00243 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLOPPLNL_00244 9.6e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLOPPLNL_00245 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HLOPPLNL_00246 4.1e-08 KT PspC domain protein
HLOPPLNL_00247 2e-85 phoR 2.7.13.3 T Histidine kinase
HLOPPLNL_00248 1e-85 K response regulator
HLOPPLNL_00249 1e-66 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HLOPPLNL_00250 1.9e-163 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLOPPLNL_00251 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLOPPLNL_00252 8.2e-96 yeaN P Major Facilitator Superfamily
HLOPPLNL_00253 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLOPPLNL_00254 1.6e-51 comFC S Competence protein
HLOPPLNL_00255 6e-127 comFA L Helicase C-terminal domain protein
HLOPPLNL_00256 1.2e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
HLOPPLNL_00257 4.1e-296 ydaO E amino acid
HLOPPLNL_00258 2.5e-269 aha1 P COG COG0474 Cation transport ATPase
HLOPPLNL_00259 1.3e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLOPPLNL_00260 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLOPPLNL_00261 1.2e-32 S CAAX protease self-immunity
HLOPPLNL_00262 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLOPPLNL_00263 3.4e-256 uup S ABC transporter, ATP-binding protein
HLOPPLNL_00264 2.4e-160 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLOPPLNL_00265 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HLOPPLNL_00266 8.2e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HLOPPLNL_00267 1.6e-140 ansA 3.5.1.1 EJ Asparaginase
HLOPPLNL_00268 4.7e-81 fat 3.1.2.21 I Acyl-ACP thioesterase
HLOPPLNL_00269 2.3e-106 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLOPPLNL_00270 1.4e-40 yabA L Involved in initiation control of chromosome replication
HLOPPLNL_00271 2.6e-82 holB 2.7.7.7 L DNA polymerase III
HLOPPLNL_00272 1.1e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLOPPLNL_00273 7.1e-29 yaaL S Protein of unknown function (DUF2508)
HLOPPLNL_00274 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLOPPLNL_00275 1.4e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLOPPLNL_00276 2.1e-212 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLOPPLNL_00277 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLOPPLNL_00278 4.2e-75 rsmC 2.1.1.172 J Methyltransferase
HLOPPLNL_00279 1.2e-27 nrdH O Glutaredoxin
HLOPPLNL_00280 1.8e-44 nrdI F NrdI Flavodoxin like
HLOPPLNL_00281 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLOPPLNL_00282 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLOPPLNL_00283 9.3e-302 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLOPPLNL_00284 1.6e-55
HLOPPLNL_00285 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLOPPLNL_00286 1.7e-74 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLOPPLNL_00287 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLOPPLNL_00288 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLOPPLNL_00289 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
HLOPPLNL_00290 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLOPPLNL_00291 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HLOPPLNL_00292 7e-71 yacP S YacP-like NYN domain
HLOPPLNL_00293 2.4e-109 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLOPPLNL_00294 3.8e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLOPPLNL_00295 1.1e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLOPPLNL_00296 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLOPPLNL_00297 4.1e-153 yacL S domain protein
HLOPPLNL_00298 3.5e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLOPPLNL_00299 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HLOPPLNL_00300 3.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
HLOPPLNL_00301 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
HLOPPLNL_00302 1e-33 S Enterocin A Immunity
HLOPPLNL_00303 2.1e-116 S Glycosyl transferase family 2
HLOPPLNL_00304 6.7e-65 D peptidase
HLOPPLNL_00305 0.0 asnB 6.3.5.4 E Asparagine synthase
HLOPPLNL_00307 2.6e-33 yiiE S Protein of unknown function (DUF1211)
HLOPPLNL_00308 2.1e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLOPPLNL_00309 6.3e-247 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HLOPPLNL_00310 9.8e-18 yneR
HLOPPLNL_00311 4.3e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLOPPLNL_00312 4.9e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
HLOPPLNL_00313 2.4e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HLOPPLNL_00314 1.9e-151 mdtG EGP Major facilitator Superfamily
HLOPPLNL_00315 3.4e-15 yobS K transcriptional regulator
HLOPPLNL_00316 2.8e-109 glcU U sugar transport
HLOPPLNL_00317 1.7e-169 yjjP S Putative threonine/serine exporter
HLOPPLNL_00318 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
HLOPPLNL_00319 6.4e-96 yicL EG EamA-like transporter family
HLOPPLNL_00320 1.2e-223 pepF E Oligopeptidase F
HLOPPLNL_00321 5.4e-111 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HLOPPLNL_00322 2.4e-177 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HLOPPLNL_00323 1.5e-25 S dextransucrase activity
HLOPPLNL_00324 1.5e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
HLOPPLNL_00325 1.5e-63 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HLOPPLNL_00326 9.5e-15 relB L RelB antitoxin
HLOPPLNL_00327 2e-173 S Putative peptidoglycan binding domain
HLOPPLNL_00328 7.1e-32 K Transcriptional regulator, MarR family
HLOPPLNL_00329 1.7e-214 XK27_09600 V ABC transporter, ATP-binding protein
HLOPPLNL_00330 4.1e-229 V ABC transporter transmembrane region
HLOPPLNL_00331 7.4e-169 uhpT EGP Mycoplasma MFS transporter
HLOPPLNL_00332 4.6e-157 lctO C FMN-dependent dehydrogenase
HLOPPLNL_00333 7.9e-106 yxeH S hydrolase
HLOPPLNL_00334 9e-114 K response regulator
HLOPPLNL_00335 2.8e-271 vicK 2.7.13.3 T Histidine kinase
HLOPPLNL_00336 7.9e-103 yycH S YycH protein
HLOPPLNL_00337 1.6e-79 yycI S YycH protein
HLOPPLNL_00338 6.8e-30 yyaQ S YjbR
HLOPPLNL_00339 1.7e-116 vicX 3.1.26.11 S domain protein
HLOPPLNL_00340 2.8e-145 htrA 3.4.21.107 O serine protease
HLOPPLNL_00341 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLOPPLNL_00342 2.7e-207 G glycerol-3-phosphate transporter
HLOPPLNL_00343 1.4e-140 S interspecies interaction between organisms
HLOPPLNL_00344 5.6e-63 secY2 U SecY translocase
HLOPPLNL_00345 4.9e-91 asp1 S Accessory Sec system protein Asp1
HLOPPLNL_00346 2e-105 asp2 3.4.11.5 S Accessory Sec system protein Asp2
HLOPPLNL_00347 2.5e-31 asp3 S Accessory Sec system protein Asp3
HLOPPLNL_00348 1.6e-247 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLOPPLNL_00351 3.9e-147 scrR K helix_turn _helix lactose operon repressor
HLOPPLNL_00352 4.8e-218 scrB 3.2.1.26 GH32 G invertase
HLOPPLNL_00353 1.2e-280 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HLOPPLNL_00354 4.1e-184 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HLOPPLNL_00355 4.2e-115 ntpJ P Potassium uptake protein
HLOPPLNL_00356 2.8e-58 ktrA P TrkA-N domain
HLOPPLNL_00357 7.4e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HLOPPLNL_00358 2.6e-37 M Glycosyltransferase like family 2
HLOPPLNL_00359 7.5e-12
HLOPPLNL_00360 4.8e-95 S Predicted membrane protein (DUF2207)
HLOPPLNL_00361 4.3e-52 bioY S BioY family
HLOPPLNL_00362 4.8e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HLOPPLNL_00363 1.7e-73 glcR K DeoR C terminal sensor domain
HLOPPLNL_00364 3.8e-60 yceE S haloacid dehalogenase-like hydrolase
HLOPPLNL_00365 5.3e-34 S Domain of unknown function (DUF4811)
HLOPPLNL_00366 4.7e-197 lmrB EGP Major facilitator Superfamily
HLOPPLNL_00367 2.1e-31 merR K MerR HTH family regulatory protein
HLOPPLNL_00368 8.7e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLOPPLNL_00369 2e-119 G Bacterial extracellular solute-binding protein
HLOPPLNL_00370 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
HLOPPLNL_00371 1.8e-99 baeS T Histidine kinase
HLOPPLNL_00372 3.1e-80 rbsB G sugar-binding domain protein
HLOPPLNL_00373 5.3e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HLOPPLNL_00374 6.4e-116 manY G PTS system sorbose-specific iic component
HLOPPLNL_00375 8e-147 manN G system, mannose fructose sorbose family IID component
HLOPPLNL_00376 3.2e-52 manO S Domain of unknown function (DUF956)
HLOPPLNL_00377 6e-70 mltD CBM50 M NlpC P60 family protein
HLOPPLNL_00378 6.8e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HLOPPLNL_00379 9.9e-166 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLOPPLNL_00380 4.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
HLOPPLNL_00381 3.7e-45 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HLOPPLNL_00382 8.1e-38 K transcriptional regulator PadR family
HLOPPLNL_00383 5.5e-19 XK27_06920 S Protein of unknown function (DUF1700)
HLOPPLNL_00384 2.4e-16 S Putative adhesin
HLOPPLNL_00385 2.2e-16 pspC KT PspC domain
HLOPPLNL_00386 5.1e-13 S Enterocin A Immunity
HLOPPLNL_00387 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLOPPLNL_00388 1.6e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HLOPPLNL_00389 2.1e-99 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HLOPPLNL_00390 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HLOPPLNL_00391 1.5e-120 potB P ABC transporter permease
HLOPPLNL_00392 1.3e-103 potC U Binding-protein-dependent transport system inner membrane component
HLOPPLNL_00393 2.2e-159 potD P ABC transporter
HLOPPLNL_00394 1e-131 ABC-SBP S ABC transporter
HLOPPLNL_00395 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HLOPPLNL_00396 2.3e-107 XK27_08845 S ABC transporter, ATP-binding protein
HLOPPLNL_00397 3.9e-68 M ErfK YbiS YcfS YnhG
HLOPPLNL_00398 1.6e-53 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLOPPLNL_00399 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLOPPLNL_00400 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLOPPLNL_00401 5.7e-102 pgm3 G phosphoglycerate mutase
HLOPPLNL_00402 1.6e-56 S CAAX protease self-immunity
HLOPPLNL_00412 1.4e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HLOPPLNL_00413 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HLOPPLNL_00414 8.7e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLOPPLNL_00415 7.9e-160 camS S sex pheromone
HLOPPLNL_00416 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLOPPLNL_00417 3.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLOPPLNL_00418 4.7e-255 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLOPPLNL_00419 9.8e-146 yegS 2.7.1.107 G Lipid kinase
HLOPPLNL_00420 3.1e-211 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLOPPLNL_00421 3.2e-121 L Mrr N-terminal domain
HLOPPLNL_00422 1.6e-13
HLOPPLNL_00423 4.5e-38 2.7.7.7 L Domain of unknown function (DUF4357)
HLOPPLNL_00424 3.8e-218 mod 2.1.1.72, 3.1.21.5 L DNA methylase
HLOPPLNL_00425 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
HLOPPLNL_00426 4.7e-145 K DNA binding
HLOPPLNL_00427 3.3e-42 K DNA binding
HLOPPLNL_00428 0.0 L helicase activity
HLOPPLNL_00429 1.7e-102 S Domain of unknown function (DUF4343)
HLOPPLNL_00430 7.7e-27 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
HLOPPLNL_00431 8.5e-73 S Domain of unknown function (DUF3841)
HLOPPLNL_00432 3.5e-177 spoVK O stage V sporulation protein K
HLOPPLNL_00433 9e-156 C Oxidoreductase
HLOPPLNL_00434 6.7e-72 ywlG S Belongs to the UPF0340 family
HLOPPLNL_00435 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HLOPPLNL_00436 3.6e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLOPPLNL_00437 2.6e-57 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLOPPLNL_00438 9.7e-178 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HLOPPLNL_00439 4.4e-14 ybaN S Protein of unknown function (DUF454)
HLOPPLNL_00440 1.1e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLOPPLNL_00441 1.2e-199 frdC 1.3.5.4 C FAD binding domain
HLOPPLNL_00442 6.9e-206 yflS P Sodium:sulfate symporter transmembrane region
HLOPPLNL_00443 2.4e-18 yncA 2.3.1.79 S Maltose acetyltransferase
HLOPPLNL_00444 1.5e-161 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLOPPLNL_00445 4.9e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
HLOPPLNL_00446 2.9e-96 ypuA S Protein of unknown function (DUF1002)
HLOPPLNL_00454 8.4e-249 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HLOPPLNL_00455 1.6e-61
HLOPPLNL_00456 1.4e-40 rpmE2 J Ribosomal protein L31
HLOPPLNL_00457 4.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HLOPPLNL_00458 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLOPPLNL_00460 2.8e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLOPPLNL_00461 2.9e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLOPPLNL_00462 5.3e-32 ywiB S Domain of unknown function (DUF1934)
HLOPPLNL_00463 9.8e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
HLOPPLNL_00464 8.6e-206 ywfO S HD domain protein
HLOPPLNL_00465 1.2e-88 S hydrolase
HLOPPLNL_00466 3.8e-104 ydcZ S Putative inner membrane exporter, YdcZ
HLOPPLNL_00467 4.6e-61
HLOPPLNL_00470 4.1e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
HLOPPLNL_00471 5.1e-22
HLOPPLNL_00472 6e-57 spoVK O ATPase family associated with various cellular activities (AAA)
HLOPPLNL_00474 3.8e-86 S overlaps another CDS with the same product name
HLOPPLNL_00475 6e-125 S overlaps another CDS with the same product name
HLOPPLNL_00476 9.4e-98 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLOPPLNL_00477 1.1e-41 bCE_4747 S Beta-lactamase superfamily domain
HLOPPLNL_00478 3.7e-176 L Probable transposase
HLOPPLNL_00479 4.3e-12 ytkL S Beta-lactamase superfamily domain
HLOPPLNL_00480 1.4e-290 ybiT S ABC transporter, ATP-binding protein
HLOPPLNL_00481 5.6e-77 2.4.2.3 F Phosphorylase superfamily
HLOPPLNL_00482 1.7e-24
HLOPPLNL_00483 1.2e-112 dkg S reductase
HLOPPLNL_00484 7e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HLOPPLNL_00485 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLOPPLNL_00486 2.3e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLOPPLNL_00487 4.3e-47 EGP Transmembrane secretion effector
HLOPPLNL_00488 5.2e-137 purR 2.4.2.7 F pur operon repressor
HLOPPLNL_00489 4.4e-36 adhR K helix_turn_helix, mercury resistance
HLOPPLNL_00490 3.8e-08 adhR K helix_turn_helix, mercury resistance
HLOPPLNL_00491 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLOPPLNL_00493 1.1e-14 M domain protein
HLOPPLNL_00494 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HLOPPLNL_00495 2.8e-166 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HLOPPLNL_00496 4.5e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLOPPLNL_00497 3e-230 lpdA 1.8.1.4 C Dehydrogenase
HLOPPLNL_00498 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
HLOPPLNL_00499 1.6e-55 S Protein of unknown function (DUF975)
HLOPPLNL_00500 4.8e-77 E GDSL-like Lipase/Acylhydrolase family
HLOPPLNL_00501 6.1e-39
HLOPPLNL_00502 4.1e-27 gcvR T Belongs to the UPF0237 family
HLOPPLNL_00503 1.4e-219 XK27_08635 S UPF0210 protein
HLOPPLNL_00504 1.5e-87 fruR K DeoR C terminal sensor domain
HLOPPLNL_00505 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HLOPPLNL_00506 1.8e-281 fruA 2.7.1.202 GT Phosphotransferase System
HLOPPLNL_00507 2e-49 cps3F
HLOPPLNL_00508 2.7e-83 S Membrane
HLOPPLNL_00509 2.4e-254 E Amino acid permease
HLOPPLNL_00510 4.2e-232 cadA P P-type ATPase
HLOPPLNL_00511 8.4e-114 degV S EDD domain protein, DegV family
HLOPPLNL_00512 4.3e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HLOPPLNL_00513 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
HLOPPLNL_00514 4.7e-26 ydiI Q Thioesterase superfamily
HLOPPLNL_00515 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HLOPPLNL_00516 2.3e-140 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HLOPPLNL_00517 1.2e-81 S L,D-transpeptidase catalytic domain
HLOPPLNL_00518 2e-165 EGP Major facilitator Superfamily
HLOPPLNL_00519 1.4e-21 K helix_turn_helix multiple antibiotic resistance protein
HLOPPLNL_00520 1.7e-225 pipD E Dipeptidase
HLOPPLNL_00521 2.1e-109 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HLOPPLNL_00522 2.6e-32 ywjH S Protein of unknown function (DUF1634)
HLOPPLNL_00523 3.8e-119 yxaA S membrane transporter protein
HLOPPLNL_00524 1.2e-27 K LysR substrate binding domain
HLOPPLNL_00525 1.8e-32 lysR5 K LysR substrate binding domain
HLOPPLNL_00526 8e-56 lssY 3.6.1.27 I phosphatidate phosphatase activity
HLOPPLNL_00527 6.4e-15 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HLOPPLNL_00528 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HLOPPLNL_00529 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HLOPPLNL_00530 1.9e-243 lysP E amino acid
HLOPPLNL_00531 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLOPPLNL_00533 0.0 rafA 3.2.1.22 G alpha-galactosidase
HLOPPLNL_00534 9.1e-201 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HLOPPLNL_00535 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HLOPPLNL_00536 9.1e-180 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLOPPLNL_00537 5.9e-111 galR K Transcriptional regulator
HLOPPLNL_00538 8.9e-289 lacS G Transporter
HLOPPLNL_00539 0.0 lacL 3.2.1.23 G -beta-galactosidase
HLOPPLNL_00540 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HLOPPLNL_00541 8e-109 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HLOPPLNL_00542 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HLOPPLNL_00543 6.9e-92 yueF S AI-2E family transporter
HLOPPLNL_00544 2.6e-97 ygaC J Belongs to the UPF0374 family
HLOPPLNL_00545 9.4e-192 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLOPPLNL_00546 3.4e-69 recX 2.4.1.337 GT4 S Regulatory protein RecX
HLOPPLNL_00547 2.3e-19 sigH K DNA-templated transcription, initiation
HLOPPLNL_00548 1.6e-22 S Cytochrome B5
HLOPPLNL_00549 1.1e-47 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
HLOPPLNL_00550 1.3e-59
HLOPPLNL_00551 2.4e-99 L Probable transposase
HLOPPLNL_00552 8.9e-62 L Resolvase, N-terminal domain
HLOPPLNL_00553 3.7e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HLOPPLNL_00554 6.6e-156 nrnB S DHHA1 domain
HLOPPLNL_00555 4.3e-91 yunF F Protein of unknown function DUF72
HLOPPLNL_00556 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
HLOPPLNL_00557 5.4e-13
HLOPPLNL_00558 2.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLOPPLNL_00559 2.3e-29 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLOPPLNL_00560 7.7e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLOPPLNL_00561 4.1e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLOPPLNL_00562 1.1e-64 S Uncharacterized protein conserved in bacteria (DUF2263)
HLOPPLNL_00563 2.7e-180 pbuG S permease
HLOPPLNL_00565 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HLOPPLNL_00566 6e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HLOPPLNL_00567 6.6e-69 coiA 3.6.4.12 S Competence protein
HLOPPLNL_00568 6.2e-231 pepF E oligoendopeptidase F
HLOPPLNL_00569 3.9e-41 yjbH Q Thioredoxin
HLOPPLNL_00570 1.1e-97 pstS P Phosphate
HLOPPLNL_00571 4.3e-116 pstC P probably responsible for the translocation of the substrate across the membrane
HLOPPLNL_00572 2.5e-121 pstA P Phosphate transport system permease protein PstA
HLOPPLNL_00573 1.3e-113 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLOPPLNL_00574 1.8e-115 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLOPPLNL_00575 1.4e-55 P Plays a role in the regulation of phosphate uptake
HLOPPLNL_00576 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HLOPPLNL_00577 1.1e-79 S VIT family
HLOPPLNL_00578 9.4e-84 S membrane
HLOPPLNL_00579 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
HLOPPLNL_00580 2.3e-65 hly S protein, hemolysin III
HLOPPLNL_00581 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
HLOPPLNL_00582 2e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLOPPLNL_00585 1.5e-13
HLOPPLNL_00586 3.5e-173 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HLOPPLNL_00587 1.3e-158 ccpA K catabolite control protein A
HLOPPLNL_00588 3.7e-42 S VanZ like family
HLOPPLNL_00589 1.5e-119 yebC K Transcriptional regulatory protein
HLOPPLNL_00590 1.8e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLOPPLNL_00591 1.1e-120 comGA NU Type II IV secretion system protein
HLOPPLNL_00592 1.3e-97 comGB NU type II secretion system
HLOPPLNL_00593 3.6e-27 comGC U competence protein ComGC
HLOPPLNL_00594 1.1e-13
HLOPPLNL_00596 9.4e-11 S Putative Competence protein ComGF
HLOPPLNL_00598 5.8e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
HLOPPLNL_00599 4.2e-184 cycA E Amino acid permease
HLOPPLNL_00600 1e-57 S Calcineurin-like phosphoesterase
HLOPPLNL_00601 1.9e-53 yutD S Protein of unknown function (DUF1027)
HLOPPLNL_00602 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLOPPLNL_00603 6e-32 S Protein of unknown function (DUF1461)
HLOPPLNL_00604 8.8e-92 dedA S SNARE associated Golgi protein
HLOPPLNL_00605 7.2e-96 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HLOPPLNL_00606 8.8e-50 yugI 5.3.1.9 J general stress protein
HLOPPLNL_00608 7.6e-146 yjeM E Amino Acid
HLOPPLNL_00609 1.2e-61 yphA GM NAD dependent epimerase/dehydratase family
HLOPPLNL_00610 6.6e-76 K Helix-turn-helix domain, rpiR family
HLOPPLNL_00611 8.6e-93 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HLOPPLNL_00612 1.5e-126 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HLOPPLNL_00613 5e-90 nanK GK ROK family
HLOPPLNL_00614 3.8e-54 ndk 2.7.4.6 F Belongs to the NDK family
HLOPPLNL_00615 3.7e-36 G single-species biofilm formation
HLOPPLNL_00616 5.1e-180 yjhC S Semialdehyde dehydrogenase, NAD binding domain
HLOPPLNL_00617 8.8e-201 gph G MFS/sugar transport protein
HLOPPLNL_00618 2.9e-219 3.2.1.18, 3.2.1.4 GH33,GH5,GH9 G BNR repeat-like domain
HLOPPLNL_00619 4.5e-75 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HLOPPLNL_00620 5.5e-113 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HLOPPLNL_00621 7.7e-41 S Iron-sulfur cluster assembly protein
HLOPPLNL_00622 2.6e-67 S Protein of unknown function (DUF1440)
HLOPPLNL_00623 1.1e-80 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HLOPPLNL_00624 1.5e-185 mtnE 2.6.1.83 E Aminotransferase
HLOPPLNL_00625 5.4e-55 sip L Belongs to the 'phage' integrase family
HLOPPLNL_00626 2.1e-19 sip L Belongs to the 'phage' integrase family
HLOPPLNL_00627 2.7e-153 S Protein of unknown function (DUF3644)
HLOPPLNL_00629 5e-25
HLOPPLNL_00631 2e-25 polC_1 2.7.7.7 L 3' exoribonuclease, RNase T-like
HLOPPLNL_00632 1.6e-155 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLOPPLNL_00633 5.1e-29 S Short C-terminal domain
HLOPPLNL_00636 4.6e-29
HLOPPLNL_00638 3.1e-29 E Zn peptidase
HLOPPLNL_00639 1.6e-28 3.4.21.88 K Helix-turn-helix domain
HLOPPLNL_00640 9.5e-11 K Helix-turn-helix
HLOPPLNL_00641 1.9e-14 K Phage regulatory protein
HLOPPLNL_00643 5.9e-26 arpU S Phage transcriptional regulator, ArpU family
HLOPPLNL_00646 3.2e-29 S Domain of unknown function (DUF4417)
HLOPPLNL_00648 3.4e-83 S head morphogenesis protein, SPP1 gp7 family
HLOPPLNL_00650 9e-27
HLOPPLNL_00651 8.8e-67 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HLOPPLNL_00652 2e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HLOPPLNL_00653 7.7e-101 hrtB V ABC transporter permease
HLOPPLNL_00654 2e-35 ygfC K Bacterial regulatory proteins, tetR family
HLOPPLNL_00655 1.6e-84 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HLOPPLNL_00656 1.1e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HLOPPLNL_00657 5.5e-45 M LysM domain protein
HLOPPLNL_00658 1.4e-116 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HLOPPLNL_00659 3.6e-98 sbcC L Putative exonuclease SbcCD, C subunit
HLOPPLNL_00660 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
HLOPPLNL_00661 7.2e-53 perR P Belongs to the Fur family
HLOPPLNL_00662 1.9e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLOPPLNL_00663 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLOPPLNL_00664 2.5e-86 S (CBS) domain
HLOPPLNL_00665 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HLOPPLNL_00666 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLOPPLNL_00667 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLOPPLNL_00668 4.3e-140 yabM S Polysaccharide biosynthesis protein
HLOPPLNL_00669 2.1e-31 yabO J S4 domain protein
HLOPPLNL_00670 2.6e-22 divIC D Septum formation initiator
HLOPPLNL_00671 1.2e-45 yabR J RNA binding
HLOPPLNL_00672 2.8e-95 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLOPPLNL_00673 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HLOPPLNL_00674 5.1e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLOPPLNL_00675 5.4e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLOPPLNL_00676 6.1e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLOPPLNL_00677 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HLOPPLNL_00678 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HLOPPLNL_00679 1.1e-209 glnP P ABC transporter
HLOPPLNL_00681 1.1e-59 uspA T Universal stress protein family
HLOPPLNL_00682 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
HLOPPLNL_00683 1.1e-25
HLOPPLNL_00684 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HLOPPLNL_00685 1.8e-109 puuD S peptidase C26
HLOPPLNL_00686 1e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLOPPLNL_00687 9.5e-150 lsa S ABC transporter
HLOPPLNL_00688 5e-150 mepA V MATE efflux family protein
HLOPPLNL_00689 2.4e-31 M Glycosyltransferase like family 2
HLOPPLNL_00690 3.9e-37 M family 8
HLOPPLNL_00691 1.3e-69 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HLOPPLNL_00692 1e-27 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HLOPPLNL_00693 6.7e-26 M Glycosyltransferase like family 2
HLOPPLNL_00694 3.5e-35 S Glycosyltransferase like family 2
HLOPPLNL_00695 2.9e-35 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HLOPPLNL_00696 4.1e-36 S glycosyl transferase family 2
HLOPPLNL_00697 8.1e-60 nss M transferase activity, transferring glycosyl groups
HLOPPLNL_00698 1.6e-92 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HLOPPLNL_00699 1e-37 cpsJ S Glycosyltransferase like family 2
HLOPPLNL_00700 1.8e-37 M Glycosyltransferase like family 2
HLOPPLNL_00701 1.1e-30 cpsJ S Glycosyltransferase like family 2
HLOPPLNL_00702 2.9e-154 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HLOPPLNL_00703 5.5e-53 arbx M family 8
HLOPPLNL_00704 4.4e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLOPPLNL_00705 2.7e-48 S Domain of unknown function (DUF956)
HLOPPLNL_00706 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HLOPPLNL_00707 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLOPPLNL_00708 3.2e-104 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLOPPLNL_00709 2e-101 cdsA 2.7.7.41 S Belongs to the CDS family
HLOPPLNL_00710 1.2e-156 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HLOPPLNL_00711 4.5e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLOPPLNL_00712 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLOPPLNL_00713 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
HLOPPLNL_00714 3.7e-170 nusA K Participates in both transcription termination and antitermination
HLOPPLNL_00715 1.4e-39 ylxR K Protein of unknown function (DUF448)
HLOPPLNL_00716 3.4e-25 ylxQ J ribosomal protein
HLOPPLNL_00717 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLOPPLNL_00718 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLOPPLNL_00719 4.8e-120 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLOPPLNL_00720 6.7e-96 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HLOPPLNL_00721 4.1e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLOPPLNL_00722 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLOPPLNL_00723 1.5e-274 dnaK O Heat shock 70 kDa protein
HLOPPLNL_00724 9.2e-161 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLOPPLNL_00725 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLOPPLNL_00727 4.6e-205 glnP P ABC transporter
HLOPPLNL_00728 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLOPPLNL_00729 1.5e-31
HLOPPLNL_00730 1.2e-111 ampC V Beta-lactamase
HLOPPLNL_00731 3.5e-110 cobQ S glutamine amidotransferase
HLOPPLNL_00732 1.8e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HLOPPLNL_00733 6.8e-86 tdk 2.7.1.21 F thymidine kinase
HLOPPLNL_00734 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLOPPLNL_00735 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLOPPLNL_00736 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLOPPLNL_00737 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLOPPLNL_00738 1.3e-96 atpB C it plays a direct role in the translocation of protons across the membrane
HLOPPLNL_00739 1.3e-18 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLOPPLNL_00740 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLOPPLNL_00741 5.4e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLOPPLNL_00742 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLOPPLNL_00743 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLOPPLNL_00744 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLOPPLNL_00745 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HLOPPLNL_00746 4.1e-15 ywzB S Protein of unknown function (DUF1146)
HLOPPLNL_00747 7.1e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLOPPLNL_00748 3.4e-167 mbl D Cell shape determining protein MreB Mrl
HLOPPLNL_00749 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HLOPPLNL_00750 1.3e-13 S Protein of unknown function (DUF2969)
HLOPPLNL_00751 6.1e-187 rodA D Belongs to the SEDS family
HLOPPLNL_00752 2.7e-26 arsC 1.20.4.1 P Belongs to the ArsC family
HLOPPLNL_00753 3.3e-94 2.7.1.89 M Phosphotransferase enzyme family
HLOPPLNL_00754 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HLOPPLNL_00755 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLOPPLNL_00756 9.8e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLOPPLNL_00757 1.2e-287 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLOPPLNL_00758 4.4e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLOPPLNL_00759 8.9e-155 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLOPPLNL_00760 7.3e-90 stp 3.1.3.16 T phosphatase
HLOPPLNL_00761 5.2e-192 KLT serine threonine protein kinase
HLOPPLNL_00762 1.1e-108 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLOPPLNL_00763 3.5e-59 thiN 2.7.6.2 H thiamine pyrophosphokinase
HLOPPLNL_00764 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HLOPPLNL_00765 4.5e-53 asp S Asp23 family, cell envelope-related function
HLOPPLNL_00766 4.3e-239 yloV S DAK2 domain fusion protein YloV
HLOPPLNL_00767 5.7e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLOPPLNL_00768 2.1e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLOPPLNL_00769 5.4e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLOPPLNL_00770 3.9e-101 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLOPPLNL_00771 4.5e-214 smc D Required for chromosome condensation and partitioning
HLOPPLNL_00772 1.1e-146 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLOPPLNL_00773 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLOPPLNL_00774 3.8e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLOPPLNL_00775 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HLOPPLNL_00776 1.1e-26 ylqC S Belongs to the UPF0109 family
HLOPPLNL_00777 2.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLOPPLNL_00778 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HLOPPLNL_00779 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
HLOPPLNL_00780 2.8e-199 yfnA E amino acid
HLOPPLNL_00781 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLOPPLNL_00782 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
HLOPPLNL_00783 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLOPPLNL_00784 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLOPPLNL_00785 2.9e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLOPPLNL_00786 1.8e-18 S Tetratricopeptide repeat
HLOPPLNL_00787 8e-216 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLOPPLNL_00788 2.3e-195 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLOPPLNL_00789 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLOPPLNL_00790 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLOPPLNL_00791 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLOPPLNL_00792 5e-23 ykzG S Belongs to the UPF0356 family
HLOPPLNL_00793 2.1e-24
HLOPPLNL_00794 2.4e-85 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLOPPLNL_00795 2.6e-30 1.1.1.27 C L-malate dehydrogenase activity
HLOPPLNL_00796 1.5e-24 yktA S Belongs to the UPF0223 family
HLOPPLNL_00797 8.2e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HLOPPLNL_00798 0.0 typA T GTP-binding protein TypA
HLOPPLNL_00799 5.4e-149 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HLOPPLNL_00800 1.6e-114 manY G PTS system
HLOPPLNL_00801 1.6e-147 manN G system, mannose fructose sorbose family IID component
HLOPPLNL_00802 2.3e-101 ftsW D Belongs to the SEDS family
HLOPPLNL_00803 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HLOPPLNL_00804 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HLOPPLNL_00805 7.2e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HLOPPLNL_00806 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLOPPLNL_00807 2.4e-131 ylbL T Belongs to the peptidase S16 family
HLOPPLNL_00808 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HLOPPLNL_00809 2.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLOPPLNL_00810 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLOPPLNL_00811 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLOPPLNL_00812 6.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLOPPLNL_00813 3.1e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HLOPPLNL_00814 5.8e-74 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLOPPLNL_00815 1.4e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HLOPPLNL_00816 1.4e-162 purD 6.3.4.13 F Belongs to the GARS family
HLOPPLNL_00817 1.9e-107 S Acyltransferase family
HLOPPLNL_00818 3.9e-279 kup P Transport of potassium into the cell
HLOPPLNL_00820 2e-20 S Domain of unknown function (DUF3284)
HLOPPLNL_00821 2.6e-159 yfmL L DEAD DEAH box helicase
HLOPPLNL_00822 1.4e-128 mocA S Oxidoreductase
HLOPPLNL_00823 2.6e-24 S Domain of unknown function (DUF4828)
HLOPPLNL_00824 3.1e-187 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HLOPPLNL_00825 8.4e-42 O ADP-ribosylglycohydrolase
HLOPPLNL_00826 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HLOPPLNL_00827 2e-210 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HLOPPLNL_00828 2.8e-34 K GNAT family
HLOPPLNL_00829 1.7e-40
HLOPPLNL_00831 5.5e-160 mgtE P Acts as a magnesium transporter
HLOPPLNL_00832 1.3e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HLOPPLNL_00833 4.9e-116 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLOPPLNL_00834 9.4e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
HLOPPLNL_00835 2.6e-254 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HLOPPLNL_00836 4.4e-36 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HLOPPLNL_00837 2.8e-193 pbuX F xanthine permease
HLOPPLNL_00838 1.3e-73 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLOPPLNL_00839 1.8e-60 acmC 3.2.1.96 NU mannosyl-glycoprotein
HLOPPLNL_00840 4.2e-64 S ECF transporter, substrate-specific component
HLOPPLNL_00841 9.7e-127 mleP S Sodium Bile acid symporter family
HLOPPLNL_00842 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HLOPPLNL_00843 6.2e-72 mleR K LysR family
HLOPPLNL_00844 1.2e-57 K transcriptional
HLOPPLNL_00845 7.6e-41 K Bacterial regulatory proteins, tetR family
HLOPPLNL_00846 6.1e-60 T Belongs to the universal stress protein A family
HLOPPLNL_00847 1.2e-44 K Copper transport repressor CopY TcrY
HLOPPLNL_00848 3.4e-24 3.2.1.18 GH33 M Rib/alpha-like repeat
HLOPPLNL_00849 2.9e-17 licT K CAT RNA binding domain
HLOPPLNL_00850 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
HLOPPLNL_00852 4.9e-36
HLOPPLNL_00853 0.0 pepN 3.4.11.2 E aminopeptidase
HLOPPLNL_00854 1.3e-43 2.7.13.3 T GHKL domain
HLOPPLNL_00855 3.5e-36 agrA KT Response regulator of the LytR AlgR family
HLOPPLNL_00856 9.7e-21 M domain protein
HLOPPLNL_00860 1.7e-168 yjjC V ABC transporter
HLOPPLNL_00861 2.9e-293 M Exporter of polyketide antibiotics
HLOPPLNL_00862 1.2e-114 K Transcriptional regulator
HLOPPLNL_00863 1.3e-302 L Transposase
HLOPPLNL_00865 3.2e-126 yvgN C Aldo keto reductase
HLOPPLNL_00866 8.3e-78 yraQ S Predicted permease
HLOPPLNL_00867 6e-82 L hmm pf00665
HLOPPLNL_00868 1.9e-189 XK27_11280 S Psort location CytoplasmicMembrane, score
HLOPPLNL_00870 9e-106 L Belongs to the 'phage' integrase family
HLOPPLNL_00871 1.1e-18 3.1.21.3 V Type I restriction modification DNA specificity domain
HLOPPLNL_00872 1.9e-59 hsdM 2.1.1.72 V type I restriction-modification system
HLOPPLNL_00874 1.6e-165 L T/G mismatch-specific endonuclease activity
HLOPPLNL_00875 2.2e-61
HLOPPLNL_00876 2.4e-67
HLOPPLNL_00877 1.5e-59 yeeA V Type II restriction enzyme, methylase subunits
HLOPPLNL_00878 6.7e-209 yeeA V Type II restriction enzyme, methylase subunits
HLOPPLNL_00879 2.4e-257 yeeB L DEAD-like helicases superfamily
HLOPPLNL_00880 8.4e-96 pstS P T5orf172
HLOPPLNL_00881 3.5e-19
HLOPPLNL_00884 5.2e-15 E amino acid
HLOPPLNL_00885 1.3e-216 L Probable transposase
HLOPPLNL_00886 5.2e-115 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HLOPPLNL_00887 5.6e-57 racA K Domain of unknown function (DUF1836)
HLOPPLNL_00888 5.4e-81 yitS S EDD domain protein, DegV family
HLOPPLNL_00889 1.8e-35 S Enterocin A Immunity
HLOPPLNL_00890 1.7e-284 hsdR 3.1.21.3 L DEAD/DEAH box helicase
HLOPPLNL_00891 8.8e-225 hsdM 2.1.1.72 V type I restriction-modification system
HLOPPLNL_00892 3.3e-110 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HLOPPLNL_00895 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLOPPLNL_00896 0.0 O Belongs to the peptidase S8 family
HLOPPLNL_00897 2.1e-26 S protein encoded in hypervariable junctions of pilus gene clusters
HLOPPLNL_00898 9e-102 qmcA O prohibitin homologues
HLOPPLNL_00900 2.3e-11 S YjcQ protein
HLOPPLNL_00901 2.4e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
HLOPPLNL_00902 1.8e-56 yqeY S YqeY-like protein
HLOPPLNL_00903 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HLOPPLNL_00904 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HLOPPLNL_00907 5.2e-101 epsJ1 M Glycosyltransferase like family 2
HLOPPLNL_00908 3.7e-84 M Glycosyltransferase sugar-binding region containing DXD motif
HLOPPLNL_00909 5.6e-93 M transferase activity, transferring glycosyl groups
HLOPPLNL_00910 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLOPPLNL_00911 7.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLOPPLNL_00912 2.2e-82 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLOPPLNL_00913 1.9e-55 dnaD L DnaD domain protein
HLOPPLNL_00914 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HLOPPLNL_00915 3.4e-142 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HLOPPLNL_00916 6.5e-34 ypmB S Protein conserved in bacteria
HLOPPLNL_00917 8.7e-229 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HLOPPLNL_00918 5.2e-93 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HLOPPLNL_00919 1.1e-117 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HLOPPLNL_00920 9.6e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HLOPPLNL_00921 3.3e-112 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLOPPLNL_00922 2.7e-103 holA 2.7.7.7 L DNA polymerase III delta subunit
HLOPPLNL_00923 4.7e-156 comEC S Competence protein ComEC
HLOPPLNL_00924 2e-69 comEB 3.5.4.12 F ComE operon protein 2
HLOPPLNL_00925 1.1e-50 comEA L Competence protein ComEA
HLOPPLNL_00926 3.4e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
HLOPPLNL_00927 1.5e-57 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HLOPPLNL_00928 2.2e-20
HLOPPLNL_00930 1.9e-121 K LysR substrate binding domain
HLOPPLNL_00931 2.6e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLOPPLNL_00933 1.8e-09 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HLOPPLNL_00934 1.1e-14 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HLOPPLNL_00935 1.4e-60 yslB S Protein of unknown function (DUF2507)
HLOPPLNL_00936 5e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLOPPLNL_00937 1.5e-41 S Phosphoesterase
HLOPPLNL_00940 5.8e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLOPPLNL_00941 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLOPPLNL_00942 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLOPPLNL_00943 2.5e-200 oatA I Acyltransferase
HLOPPLNL_00944 1.8e-16
HLOPPLNL_00946 1.2e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLOPPLNL_00947 6.9e-102 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HLOPPLNL_00948 2e-218 recJ L Single-stranded-DNA-specific exonuclease RecJ
HLOPPLNL_00949 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLOPPLNL_00950 2.3e-295 S membrane
HLOPPLNL_00951 3.4e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
HLOPPLNL_00952 1.4e-27 S Protein of unknown function (DUF3290)
HLOPPLNL_00953 2.5e-75 yviA S Protein of unknown function (DUF421)
HLOPPLNL_00955 5.9e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HLOPPLNL_00956 6.5e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HLOPPLNL_00957 6.5e-66 pgm3 G phosphoglycerate mutase family
HLOPPLNL_00958 3.9e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HLOPPLNL_00959 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLOPPLNL_00960 4.5e-218 yifK E Amino acid permease
HLOPPLNL_00961 3.1e-202 oppA E ABC transporter, substratebinding protein
HLOPPLNL_00962 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLOPPLNL_00963 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLOPPLNL_00964 1.3e-180 oppD P Belongs to the ABC transporter superfamily
HLOPPLNL_00965 1.3e-155 oppF P Belongs to the ABC transporter superfamily
HLOPPLNL_00966 2e-15 psiE S Phosphate-starvation-inducible E
HLOPPLNL_00967 4.7e-207 mmuP E amino acid
HLOPPLNL_00968 6.2e-115 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HLOPPLNL_00969 4e-40 K LytTr DNA-binding domain
HLOPPLNL_00970 1.7e-17 S Protein of unknown function (DUF3021)
HLOPPLNL_00971 4.5e-151 yfeX P Peroxidase
HLOPPLNL_00972 2.2e-28 tetR K Transcriptional regulator C-terminal region
HLOPPLNL_00973 7e-181 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
HLOPPLNL_00974 6.2e-11 L An automated process has identified a potential problem with this gene model
HLOPPLNL_00975 2.3e-52 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLOPPLNL_00976 1.4e-162 oxlT P Major Facilitator Superfamily
HLOPPLNL_00977 3.4e-67 ybbL S ABC transporter
HLOPPLNL_00978 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
HLOPPLNL_00980 2.6e-08 3.1.3.48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HLOPPLNL_00983 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HLOPPLNL_00984 9.5e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLOPPLNL_00985 4e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HLOPPLNL_00986 8.3e-68 XK27_09620 S NADPH-dependent FMN reductase
HLOPPLNL_00987 1.1e-157 XK27_09615 S reductase
HLOPPLNL_00988 3.4e-39 2.7.7.65 T phosphorelay sensor kinase activity
HLOPPLNL_00989 3.3e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HLOPPLNL_00990 3.4e-55 S Psort location CytoplasmicMembrane, score
HLOPPLNL_00991 3.6e-14
HLOPPLNL_00992 2.7e-71 S Bacterial membrane protein, YfhO
HLOPPLNL_00993 3.8e-16 S Bacterial membrane protein, YfhO
HLOPPLNL_00994 3.7e-66 S Bacterial membrane protein, YfhO
HLOPPLNL_00995 1.9e-129 S Bacterial membrane protein YfhO
HLOPPLNL_00996 3.9e-163 XK27_08315 M Sulfatase
HLOPPLNL_00997 1.1e-07 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HLOPPLNL_00998 5.6e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HLOPPLNL_00999 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLOPPLNL_01000 8.7e-64 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLOPPLNL_01001 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
HLOPPLNL_01002 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLOPPLNL_01003 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLOPPLNL_01004 4.2e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLOPPLNL_01005 9e-20 yaaA S S4 domain protein YaaA
HLOPPLNL_01006 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLOPPLNL_01007 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLOPPLNL_01008 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HLOPPLNL_01009 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLOPPLNL_01010 4.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLOPPLNL_01011 1.1e-199 nupG F Nucleoside
HLOPPLNL_01012 1.5e-122 MA20_14895 S Conserved hypothetical protein 698
HLOPPLNL_01013 2.9e-53 K LysR substrate binding domain
HLOPPLNL_01014 1.8e-07
HLOPPLNL_01015 1.8e-65 yxkH G Polysaccharide deacetylase
HLOPPLNL_01016 9e-30 yqkB S Belongs to the HesB IscA family
HLOPPLNL_01017 1.2e-128 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
HLOPPLNL_01018 9.8e-75 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HLOPPLNL_01019 7e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HLOPPLNL_01020 1.3e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HLOPPLNL_01021 1.3e-40 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
HLOPPLNL_01022 1e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
HLOPPLNL_01023 4.1e-202 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HLOPPLNL_01024 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HLOPPLNL_01025 1.1e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HLOPPLNL_01026 1.9e-136 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HLOPPLNL_01027 5.6e-150 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HLOPPLNL_01028 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HLOPPLNL_01029 2.5e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HLOPPLNL_01030 5.9e-253 ctpA 3.6.3.54 P P-type ATPase
HLOPPLNL_01031 7.2e-31 gtcA S Teichoic acid glycosylation protein
HLOPPLNL_01032 1.9e-114 rfbJ M Glycosyl transferase family 2
HLOPPLNL_01033 1.9e-33 S Predicted membrane protein (DUF2142)
HLOPPLNL_01034 1.6e-31 K Acetyltransferase (GNAT) domain
HLOPPLNL_01036 2.6e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HLOPPLNL_01037 1.9e-132 coaA 2.7.1.33 F Pantothenic acid kinase
HLOPPLNL_01038 6.3e-44 E GDSL-like Lipase/Acylhydrolase
HLOPPLNL_01039 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLOPPLNL_01040 7.3e-190 glnPH2 P ABC transporter permease
HLOPPLNL_01041 1e-212 yjeM E Amino Acid
HLOPPLNL_01042 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
HLOPPLNL_01043 6.6e-138 tetA EGP Major facilitator Superfamily
HLOPPLNL_01045 4e-69 rny D Peptidase family M23
HLOPPLNL_01047 1.3e-68 xerD L Phage integrase, N-terminal SAM-like domain
HLOPPLNL_01048 1.3e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLOPPLNL_01049 6.3e-108 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLOPPLNL_01050 1e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLOPPLNL_01051 1.7e-276 yfmR S ABC transporter, ATP-binding protein
HLOPPLNL_01052 2.6e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLOPPLNL_01053 2.7e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLOPPLNL_01056 8.5e-80 ypmR E GDSL-like Lipase/Acylhydrolase
HLOPPLNL_01057 4.4e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HLOPPLNL_01058 3.6e-24 yozE S Belongs to the UPF0346 family
HLOPPLNL_01059 1.2e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLOPPLNL_01060 6.3e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLOPPLNL_01061 5.3e-84 dprA LU DNA protecting protein DprA
HLOPPLNL_01062 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLOPPLNL_01063 1e-208 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HLOPPLNL_01064 3.9e-14
HLOPPLNL_01065 5e-76 S DNA primase
HLOPPLNL_01066 4.3e-45 L DNA replication protein
HLOPPLNL_01072 4.5e-07 S sequence-specific DNA binding
HLOPPLNL_01073 1.3e-11 K Cro/C1-type HTH DNA-binding domain
HLOPPLNL_01074 7.5e-118 sip L Belongs to the 'phage' integrase family
HLOPPLNL_01075 2.2e-204 G PTS system Galactitol-specific IIC component
HLOPPLNL_01076 7.4e-151 M Exporter of polyketide antibiotics
HLOPPLNL_01077 4.4e-99 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HLOPPLNL_01078 4.6e-35 S Repeat protein
HLOPPLNL_01079 4e-278 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLOPPLNL_01083 6.5e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLOPPLNL_01084 6.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HLOPPLNL_01085 9.1e-43 yodB K Transcriptional regulator, HxlR family
HLOPPLNL_01086 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLOPPLNL_01087 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLOPPLNL_01088 1.8e-127 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HLOPPLNL_01089 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
HLOPPLNL_01090 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLOPPLNL_01091 6.4e-12
HLOPPLNL_01092 3e-144 iunH2 3.2.2.1 F nucleoside hydrolase
HLOPPLNL_01093 2e-43 XK27_03960 S Protein of unknown function (DUF3013)
HLOPPLNL_01094 1.3e-117 prmA J Ribosomal protein L11 methyltransferase
HLOPPLNL_01095 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLOPPLNL_01096 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLOPPLNL_01097 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLOPPLNL_01098 6.7e-57 3.1.3.18 J HAD-hyrolase-like
HLOPPLNL_01099 9.9e-42 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLOPPLNL_01100 9.6e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HLOPPLNL_01101 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLOPPLNL_01102 3.5e-204 pyrP F Permease
HLOPPLNL_01103 3.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HLOPPLNL_01104 5e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HLOPPLNL_01105 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLOPPLNL_01106 3.3e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLOPPLNL_01107 3.7e-134 K Transcriptional regulator
HLOPPLNL_01108 1.1e-143 ppaC 3.6.1.1 C inorganic pyrophosphatase
HLOPPLNL_01109 2.5e-114 glcR K DeoR C terminal sensor domain
HLOPPLNL_01110 2.2e-170 patA 2.6.1.1 E Aminotransferase
HLOPPLNL_01111 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HLOPPLNL_01113 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLOPPLNL_01114 4.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HLOPPLNL_01115 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
HLOPPLNL_01116 1.5e-22 S Family of unknown function (DUF5322)
HLOPPLNL_01117 2.2e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HLOPPLNL_01118 8e-39
HLOPPLNL_01125 1.9e-149 EGP Sugar (and other) transporter
HLOPPLNL_01126 2.3e-77 trmK 2.1.1.217 S SAM-dependent methyltransferase
HLOPPLNL_01127 4.3e-104 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLOPPLNL_01128 9.4e-183 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HLOPPLNL_01129 5.1e-71 alkD L DNA alkylation repair enzyme
HLOPPLNL_01130 6.4e-136 EG EamA-like transporter family
HLOPPLNL_01131 3.1e-149 S Tetratricopeptide repeat protein
HLOPPLNL_01132 2.6e-204 hisS 6.1.1.21 J histidyl-tRNA synthetase
HLOPPLNL_01133 1.5e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HLOPPLNL_01134 2.7e-126 corA P CorA-like Mg2+ transporter protein
HLOPPLNL_01135 1.1e-160 nhaC C Na H antiporter NhaC
HLOPPLNL_01136 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLOPPLNL_01137 8.4e-80 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HLOPPLNL_01139 2.5e-86 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLOPPLNL_01140 3.4e-155 iscS 2.8.1.7 E Aminotransferase class V
HLOPPLNL_01141 3.7e-41 XK27_04120 S Putative amino acid metabolism
HLOPPLNL_01142 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLOPPLNL_01143 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLOPPLNL_01144 5.6e-15 S Protein of unknown function (DUF2929)
HLOPPLNL_01145 0.0 dnaE 2.7.7.7 L DNA polymerase
HLOPPLNL_01146 1.5e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HLOPPLNL_01147 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HLOPPLNL_01149 1e-39 ypaA S Protein of unknown function (DUF1304)
HLOPPLNL_01150 4.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLOPPLNL_01151 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLOPPLNL_01152 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLOPPLNL_01153 5e-203 FbpA K Fibronectin-binding protein
HLOPPLNL_01154 3.1e-40 K Transcriptional regulator
HLOPPLNL_01155 1.8e-116 degV S EDD domain protein, DegV family
HLOPPLNL_01156 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
HLOPPLNL_01157 2.4e-40 6.3.3.2 S ASCH
HLOPPLNL_01158 4.4e-188 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLOPPLNL_01159 1.5e-78 yjjH S Calcineurin-like phosphoesterase
HLOPPLNL_01160 2.9e-93 EG EamA-like transporter family
HLOPPLNL_01162 2.1e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLOPPLNL_01163 2.4e-31 metI U ABC transporter permease
HLOPPLNL_01164 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
HLOPPLNL_01165 2.2e-54 S Protein of unknown function (DUF4256)
HLOPPLNL_01167 2.3e-75 M transferase activity, transferring glycosyl groups
HLOPPLNL_01168 3.1e-58 cps3F
HLOPPLNL_01169 1.2e-160 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HLOPPLNL_01170 3.4e-66 S Glycosyltransferase like family 2
HLOPPLNL_01171 1.2e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
HLOPPLNL_01172 4.3e-97 M Core-2/I-Branching enzyme
HLOPPLNL_01173 1.1e-89 rfbP M Bacterial sugar transferase
HLOPPLNL_01174 5.7e-127 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HLOPPLNL_01175 1.2e-111 ywqE 3.1.3.48 GM PHP domain protein
HLOPPLNL_01176 1.3e-80 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HLOPPLNL_01177 2e-77 epsB M biosynthesis protein
HLOPPLNL_01178 1.7e-215 ugd 1.1.1.22 M UDP binding domain
HLOPPLNL_01179 3.8e-93 yihY S Belongs to the UPF0761 family
HLOPPLNL_01180 2.3e-11 mltD CBM50 M Lysin motif
HLOPPLNL_01181 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HLOPPLNL_01182 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
HLOPPLNL_01183 5.1e-54 fld C Flavodoxin
HLOPPLNL_01184 8.7e-53 gtcA S Teichoic acid glycosylation protein
HLOPPLNL_01185 0.0 S Bacterial membrane protein YfhO
HLOPPLNL_01186 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
HLOPPLNL_01187 2.2e-122 S Sulfite exporter TauE/SafE
HLOPPLNL_01188 1.1e-70 K Sugar-specific transcriptional regulator TrmB
HLOPPLNL_01189 7.1e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLOPPLNL_01190 1e-181 pepS E Thermophilic metalloprotease (M29)
HLOPPLNL_01191 7.6e-41 trxA O Belongs to the thioredoxin family
HLOPPLNL_01192 6.1e-308 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLOPPLNL_01193 1.2e-17 cvpA S Colicin V production protein
HLOPPLNL_01194 6.4e-16 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HLOPPLNL_01195 1.9e-33 yrzB S Belongs to the UPF0473 family
HLOPPLNL_01196 5.2e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLOPPLNL_01197 2.1e-36 yrzL S Belongs to the UPF0297 family
HLOPPLNL_01198 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLOPPLNL_01199 2.3e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLOPPLNL_01200 5.5e-122 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HLOPPLNL_01201 7.5e-13
HLOPPLNL_01203 1.6e-197 dtpT U amino acid peptide transporter
HLOPPLNL_01204 1.1e-07
HLOPPLNL_01206 5e-89 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLOPPLNL_01207 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
HLOPPLNL_01208 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HLOPPLNL_01209 2.8e-242 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLOPPLNL_01210 2.3e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLOPPLNL_01211 4.8e-251 yhgF K Tex-like protein N-terminal domain protein
HLOPPLNL_01212 1.5e-42 ydcK S Belongs to the SprT family
HLOPPLNL_01214 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLOPPLNL_01215 4.5e-129 mleP2 S Sodium Bile acid symporter family
HLOPPLNL_01216 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLOPPLNL_01217 7.8e-106 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HLOPPLNL_01218 1.9e-22 XK27_09445 S Domain of unknown function (DUF1827)
HLOPPLNL_01219 0.0 clpE O Belongs to the ClpA ClpB family
HLOPPLNL_01220 2.6e-15
HLOPPLNL_01221 9.7e-37 ptsH G phosphocarrier protein HPR
HLOPPLNL_01222 2.6e-284 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLOPPLNL_01223 2e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HLOPPLNL_01224 1.3e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
HLOPPLNL_01225 1.5e-125 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLOPPLNL_01226 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
HLOPPLNL_01227 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLOPPLNL_01228 5.1e-38 S Replication initiator protein A (RepA) N-terminus
HLOPPLNL_01229 6.1e-108 L Initiator Replication protein
HLOPPLNL_01230 2.7e-08 yokH G regulation of fungal-type cell wall biogenesis
HLOPPLNL_01232 3.3e-181 L PLD-like domain
HLOPPLNL_01233 2.8e-45 L Transposase
HLOPPLNL_01234 1.6e-17 S Protein of unknown function (DUF805)
HLOPPLNL_01235 1.3e-236 tetP J elongation factor G
HLOPPLNL_01236 1.2e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLOPPLNL_01238 5.9e-52 yjeM E Amino Acid
HLOPPLNL_01239 0.0 LV site-specific DNA-methyltransferase (adenine-specific) activity
HLOPPLNL_01240 2.5e-59 L Resolvase, N terminal domain
HLOPPLNL_01242 1.7e-19 S Psort location Cytoplasmic, score 8.87
HLOPPLNL_01244 4.1e-140 D CobQ CobB MinD ParA nucleotide binding domain protein
HLOPPLNL_01245 6.1e-29
HLOPPLNL_01247 2.9e-39 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HLOPPLNL_01248 4.8e-53 3.1.21.3 V Type I restriction modification DNA specificity domain
HLOPPLNL_01249 2.9e-24 L Addiction module antitoxin, RelB DinJ family
HLOPPLNL_01250 4.5e-23 S Addiction module toxin RelE StbE family
HLOPPLNL_01251 6e-62 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HLOPPLNL_01252 1.4e-137 L Belongs to the 'phage' integrase family
HLOPPLNL_01253 7.4e-241 hsdM 2.1.1.72 V HsdM N-terminal domain
HLOPPLNL_01254 3e-85 hsdS 3.1.21.3 V PFAM restriction modification system DNA specificity domain
HLOPPLNL_01255 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HLOPPLNL_01256 9.9e-47 3.1.21.3 V Type I restriction modification DNA specificity domain
HLOPPLNL_01257 3.5e-176 thrC 4.2.3.1 E Threonine synthase
HLOPPLNL_01258 3.8e-126 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLOPPLNL_01259 2e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HLOPPLNL_01260 1.6e-88 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HLOPPLNL_01261 8.6e-127 S Membrane protein involved in the export of O-antigen and teichoic acid
HLOPPLNL_01262 3.1e-46 M Glycosyltransferase like family 2
HLOPPLNL_01263 2e-42 S Psort location CytoplasmicMembrane, score 9.99
HLOPPLNL_01264 2e-81 cps3B S Glycosyl transferase family 2
HLOPPLNL_01265 1.4e-76 GT2,GT4 M cyclopropane-fatty-acyl-phospholipid synthase
HLOPPLNL_01266 1.4e-96 M Glycosyl transferase family 8
HLOPPLNL_01267 1.6e-130 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLOPPLNL_01268 1.2e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLOPPLNL_01269 6.5e-102 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HLOPPLNL_01270 5.4e-145 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLOPPLNL_01271 1.7e-75 S Glycosyltransferase like family 2
HLOPPLNL_01272 4.3e-61 S Glycosyltransferase like family 2
HLOPPLNL_01273 1.1e-115 cps1D M Domain of unknown function (DUF4422)
HLOPPLNL_01274 4.4e-38 S CAAX protease self-immunity
HLOPPLNL_01275 3.5e-88 yvyE 3.4.13.9 S YigZ family
HLOPPLNL_01276 1.7e-58 S Haloacid dehalogenase-like hydrolase
HLOPPLNL_01277 2.6e-154 EGP Major facilitator Superfamily
HLOPPLNL_01279 1.1e-68 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HLOPPLNL_01280 4.1e-28 K helix_turn_helix, mercury resistance
HLOPPLNL_01281 1.7e-89 S NADPH-dependent FMN reductase
HLOPPLNL_01282 6.8e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HLOPPLNL_01283 3.2e-55 S ECF transporter, substrate-specific component
HLOPPLNL_01284 2.8e-95 znuB U ABC 3 transport family
HLOPPLNL_01285 1e-98 fhuC P ABC transporter
HLOPPLNL_01286 2.7e-104 psaA P Belongs to the bacterial solute-binding protein 9 family
HLOPPLNL_01287 1.5e-38
HLOPPLNL_01288 1.4e-53 XK27_01040 S Protein of unknown function (DUF1129)
HLOPPLNL_01289 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLOPPLNL_01290 1.5e-23 yyzM S Bacterial protein of unknown function (DUF951)
HLOPPLNL_01291 2e-107 spo0J K Belongs to the ParB family
HLOPPLNL_01292 6.5e-118 soj D Sporulation initiation inhibitor
HLOPPLNL_01293 2.2e-82 noc K Belongs to the ParB family
HLOPPLNL_01294 2.4e-101 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HLOPPLNL_01295 1.6e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HLOPPLNL_01296 1.6e-81 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLOPPLNL_01297 1.1e-109 3.1.4.46 C phosphodiesterase
HLOPPLNL_01298 0.0 pacL 3.6.3.8 P P-type ATPase
HLOPPLNL_01299 1.5e-60 yvdD 3.2.2.10 S Possible lysine decarboxylase
HLOPPLNL_01300 1.4e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HLOPPLNL_01302 4e-63 srtA 3.4.22.70 M sortase family
HLOPPLNL_01303 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HLOPPLNL_01304 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HLOPPLNL_01305 8.2e-34
HLOPPLNL_01306 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLOPPLNL_01307 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLOPPLNL_01308 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLOPPLNL_01309 1.8e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
HLOPPLNL_01310 7.3e-59 1.13.11.2 S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLOPPLNL_01311 1.1e-39 ybjQ S Belongs to the UPF0145 family
HLOPPLNL_01312 3.9e-09
HLOPPLNL_01313 1.2e-94 V ABC transporter, ATP-binding protein
HLOPPLNL_01314 1.1e-41 gntR1 K Transcriptional regulator, GntR family
HLOPPLNL_01315 3.2e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HLOPPLNL_01316 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLOPPLNL_01317 3.8e-262 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HLOPPLNL_01318 2.2e-107 terC P Integral membrane protein TerC family
HLOPPLNL_01319 1.9e-39 K Transcriptional regulator
HLOPPLNL_01320 2.2e-95 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HLOPPLNL_01321 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLOPPLNL_01322 4.5e-102 tcyB E ABC transporter
HLOPPLNL_01324 7.6e-46 M Glycosyl hydrolases family 25
HLOPPLNL_01325 3.6e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HLOPPLNL_01326 7.8e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLOPPLNL_01327 3.4e-209 mtlR K Mga helix-turn-helix domain
HLOPPLNL_01328 2.4e-175 yjcE P Sodium proton antiporter
HLOPPLNL_01329 3.8e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HLOPPLNL_01330 3.1e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
HLOPPLNL_01331 3.3e-69 dhaL 2.7.1.121 S Dak2
HLOPPLNL_01332 3.8e-150 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HLOPPLNL_01333 1e-112 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HLOPPLNL_01334 1.7e-61 K Bacterial regulatory proteins, tetR family
HLOPPLNL_01335 5e-209 brnQ U Component of the transport system for branched-chain amino acids
HLOPPLNL_01337 1.7e-111 endA F DNA RNA non-specific endonuclease
HLOPPLNL_01338 4.1e-75 XK27_02070 S Nitroreductase family
HLOPPLNL_01339 3.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HLOPPLNL_01340 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HLOPPLNL_01341 3.6e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
HLOPPLNL_01342 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HLOPPLNL_01343 5.5e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HLOPPLNL_01344 1.5e-76 azlC E branched-chain amino acid
HLOPPLNL_01345 4.7e-33 azlD S Branched-chain amino acid transport protein (AzlD)
HLOPPLNL_01346 9e-57 ohrR K helix_turn_helix multiple antibiotic resistance protein
HLOPPLNL_01347 7.2e-56 jag S R3H domain protein
HLOPPLNL_01348 9.1e-54 K Transcriptional regulator C-terminal region
HLOPPLNL_01349 5.9e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
HLOPPLNL_01350 3.7e-287 pepO 3.4.24.71 O Peptidase family M13
HLOPPLNL_01351 8.5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
HLOPPLNL_01354 2.1e-69 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HLOPPLNL_01355 5.1e-47 hmpT S ECF-type riboflavin transporter, S component
HLOPPLNL_01356 1.3e-40 wecD K Acetyltransferase GNAT Family
HLOPPLNL_01358 7e-249 XK27_06780 V ABC transporter permease
HLOPPLNL_01359 7.1e-95 XK27_06785 V ABC transporter, ATP-binding protein
HLOPPLNL_01360 8.6e-35 tetR K transcriptional regulator
HLOPPLNL_01361 2.8e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLOPPLNL_01362 5.3e-64 C FMN binding
HLOPPLNL_01363 1.8e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HLOPPLNL_01364 1.7e-54 rplI J Binds to the 23S rRNA
HLOPPLNL_01365 6.1e-264 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HLOPPLNL_01366 1.4e-06
HLOPPLNL_01368 1.5e-282 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HLOPPLNL_01369 5.4e-180 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HLOPPLNL_01370 8.8e-28 yphH S Cupin domain
HLOPPLNL_01371 1.2e-83 drgA C nitroreductase
HLOPPLNL_01372 5.1e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HLOPPLNL_01373 8.6e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HLOPPLNL_01374 2.4e-171 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HLOPPLNL_01375 4.1e-263 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HLOPPLNL_01376 1.6e-31 2.7.13.3 T GHKL domain
HLOPPLNL_01381 1.1e-16
HLOPPLNL_01382 1.2e-12
HLOPPLNL_01384 7.2e-08
HLOPPLNL_01385 6.6e-87 S Haloacid dehalogenase-like hydrolase
HLOPPLNL_01386 2.7e-15
HLOPPLNL_01388 8.7e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLOPPLNL_01389 1.2e-59 ykhA 3.1.2.20 I Thioesterase superfamily
HLOPPLNL_01390 7.9e-12 S CAAX protease self-immunity
HLOPPLNL_01391 9.5e-82 S Belongs to the UPF0246 family
HLOPPLNL_01392 1.3e-94 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HLOPPLNL_01393 3e-94 L PFAM Integrase catalytic region
HLOPPLNL_01394 3.2e-85 dps P Ferritin-like domain
HLOPPLNL_01395 3e-125 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HLOPPLNL_01396 4.8e-32 P Heavy-metal-associated domain
HLOPPLNL_01397 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HLOPPLNL_01399 1.7e-32 L PFAM Integrase catalytic region
HLOPPLNL_01401 2.8e-176 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLOPPLNL_01402 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLOPPLNL_01403 1.1e-16 EGP Major Facilitator Superfamily
HLOPPLNL_01404 2.6e-129 EGP Major Facilitator Superfamily
HLOPPLNL_01405 1.8e-35 L Integrase core domain
HLOPPLNL_01406 5.5e-91 L Transposase, IS605 OrfB family
HLOPPLNL_01407 1e-54 tlpA2 L Transposase IS200 like
HLOPPLNL_01408 4.5e-57 S peptidoglycan catabolic process
HLOPPLNL_01409 3.2e-197 XK27_08315 M Sulfatase
HLOPPLNL_01411 1.4e-167 mdtG EGP Major facilitator Superfamily
HLOPPLNL_01412 1.7e-114 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HLOPPLNL_01413 6.7e-17 treB G phosphotransferase system
HLOPPLNL_01414 3.5e-63 3.1.3.73 G phosphoglycerate mutase
HLOPPLNL_01415 1.8e-82 pncA Q isochorismatase
HLOPPLNL_01416 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HLOPPLNL_01417 6.4e-102 ydhQ K UbiC transcription regulator-associated domain protein
HLOPPLNL_01418 6.4e-194 tnpB L Putative transposase DNA-binding domain
HLOPPLNL_01419 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HLOPPLNL_01420 1.3e-41 K Transcriptional regulator, HxlR family
HLOPPLNL_01421 1.1e-163 C Luciferase-like monooxygenase
HLOPPLNL_01422 1.7e-67 1.5.1.38 S NADPH-dependent FMN reductase
HLOPPLNL_01423 2.6e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HLOPPLNL_01424 5.2e-76 L haloacid dehalogenase-like hydrolase
HLOPPLNL_01425 7.5e-60 EG EamA-like transporter family
HLOPPLNL_01426 3.1e-118 K AI-2E family transporter
HLOPPLNL_01427 3.2e-172 malY 4.4.1.8 E Aminotransferase, class I
HLOPPLNL_01428 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLOPPLNL_01429 7.6e-17
HLOPPLNL_01430 1.2e-95 V domain protein
HLOPPLNL_01431 1.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
HLOPPLNL_01432 2e-17
HLOPPLNL_01433 1.9e-104 azlC E AzlC protein
HLOPPLNL_01434 1.3e-38 azlD S branched-chain amino acid
HLOPPLNL_01435 5.6e-67 I alpha/beta hydrolase fold
HLOPPLNL_01436 6.9e-25
HLOPPLNL_01437 2.1e-58 3.6.1.27 I phosphatase
HLOPPLNL_01438 2e-22
HLOPPLNL_01439 4.9e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HLOPPLNL_01440 1.8e-89 sirR K Helix-turn-helix diphteria tox regulatory element
HLOPPLNL_01441 3.1e-27 cspC K Cold shock protein
HLOPPLNL_01442 4.3e-82 thrE S Putative threonine/serine exporter
HLOPPLNL_01443 2.4e-48 S Threonine/Serine exporter, ThrE
HLOPPLNL_01444 1.2e-120 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HLOPPLNL_01445 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
HLOPPLNL_01446 1.9e-34 trxA O Belongs to the thioredoxin family
HLOPPLNL_01447 7.2e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLOPPLNL_01448 5.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLOPPLNL_01449 1.9e-65 degV S Uncharacterised protein, DegV family COG1307
HLOPPLNL_01451 4.3e-54 queT S QueT transporter
HLOPPLNL_01452 1.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
HLOPPLNL_01453 5e-102 IQ Enoyl-(Acyl carrier protein) reductase
HLOPPLNL_01454 5.6e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLOPPLNL_01455 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLOPPLNL_01456 3.8e-87 S Alpha beta hydrolase
HLOPPLNL_01457 2.4e-44 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLOPPLNL_01458 6.2e-140 V MatE
HLOPPLNL_01459 8.9e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
HLOPPLNL_01460 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLOPPLNL_01461 5.6e-97 V ABC transporter
HLOPPLNL_01462 9.6e-132 bacI V MacB-like periplasmic core domain
HLOPPLNL_01463 1.5e-76 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HLOPPLNL_01464 1.7e-26
HLOPPLNL_01465 2.1e-180 yhdP S Transporter associated domain
HLOPPLNL_01466 4.1e-80 ptp2 3.1.3.48 T Tyrosine phosphatase family
HLOPPLNL_01467 0.0 L Helicase C-terminal domain protein
HLOPPLNL_01468 3.3e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLOPPLNL_01469 4.8e-212 yfnA E Amino Acid
HLOPPLNL_01470 3.2e-53 zur P Belongs to the Fur family
HLOPPLNL_01471 2.9e-07 3.2.1.14 GH18
HLOPPLNL_01472 7.2e-97
HLOPPLNL_01473 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLOPPLNL_01474 1.5e-99 glnH ET ABC transporter
HLOPPLNL_01475 1.2e-85 gluC P ABC transporter permease
HLOPPLNL_01476 2.8e-77 glnP P ABC transporter permease
HLOPPLNL_01477 1.1e-181 steT E amino acid
HLOPPLNL_01478 1.9e-20 K Acetyltransferase (GNAT) domain
HLOPPLNL_01479 8.2e-114 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HLOPPLNL_01480 3.4e-42 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HLOPPLNL_01481 2.2e-58 K rpiR family
HLOPPLNL_01483 4.7e-166 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLOPPLNL_01484 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HLOPPLNL_01485 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLOPPLNL_01486 1e-100 rplD J Forms part of the polypeptide exit tunnel
HLOPPLNL_01487 3.8e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLOPPLNL_01488 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLOPPLNL_01489 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLOPPLNL_01490 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLOPPLNL_01491 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLOPPLNL_01492 8.1e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLOPPLNL_01493 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HLOPPLNL_01494 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLOPPLNL_01495 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLOPPLNL_01496 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLOPPLNL_01497 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLOPPLNL_01498 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLOPPLNL_01499 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLOPPLNL_01500 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLOPPLNL_01501 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLOPPLNL_01502 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLOPPLNL_01503 2.1e-22 rpmD J Ribosomal protein L30
HLOPPLNL_01504 2.3e-67 rplO J Binds to the 23S rRNA
HLOPPLNL_01505 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLOPPLNL_01506 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLOPPLNL_01507 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLOPPLNL_01508 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HLOPPLNL_01509 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLOPPLNL_01510 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLOPPLNL_01511 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLOPPLNL_01512 4.8e-53 rplQ J Ribosomal protein L17
HLOPPLNL_01513 1.4e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLOPPLNL_01514 1.5e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLOPPLNL_01515 2.2e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLOPPLNL_01516 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLOPPLNL_01517 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLOPPLNL_01518 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
HLOPPLNL_01519 2.3e-30
HLOPPLNL_01520 2e-245 yjbQ P TrkA C-terminal domain protein
HLOPPLNL_01521 0.0 helD 3.6.4.12 L DNA helicase
HLOPPLNL_01522 3.2e-183 L Probable transposase
HLOPPLNL_01523 2e-30 L Helix-turn-helix domain
HLOPPLNL_01524 1.4e-90 L PFAM Integrase catalytic region
HLOPPLNL_01525 1.6e-97 tnp2 L Transposase
HLOPPLNL_01526 3.9e-237 L Transposase
HLOPPLNL_01528 1.3e-30 S Cell surface protein
HLOPPLNL_01530 1.1e-105 L transposase, IS605 OrfB family
HLOPPLNL_01531 1.7e-63 K helix_turn_helix, arabinose operon control protein
HLOPPLNL_01532 5.9e-46
HLOPPLNL_01533 3.4e-205 pipD E Dipeptidase
HLOPPLNL_01534 1.3e-22 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HLOPPLNL_01535 1.4e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLOPPLNL_01536 6.6e-61 speG J Acetyltransferase (GNAT) domain
HLOPPLNL_01537 1.8e-113 yitU 3.1.3.104 S hydrolase
HLOPPLNL_01538 9e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HLOPPLNL_01539 1.8e-80
HLOPPLNL_01540 3.4e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HLOPPLNL_01541 4.6e-43 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HLOPPLNL_01543 1.5e-83 qorB 1.6.5.2 GM NmrA-like family
HLOPPLNL_01544 3.3e-40 K Transcriptional regulator
HLOPPLNL_01545 4.9e-32 S CHY zinc finger
HLOPPLNL_01546 2.4e-32 1.1.1.1 C nadph quinone reductase
HLOPPLNL_01547 1.4e-26 1.1.1.1 C Zinc-binding dehydrogenase
HLOPPLNL_01549 8.1e-26 ybl78 L Conserved phage C-terminus (Phg_2220_C)
HLOPPLNL_01551 1.3e-40 wecD M Acetyltransferase (GNAT) family
HLOPPLNL_01552 1.6e-76 cps2D 5.1.3.2 M RmlD substrate binding domain
HLOPPLNL_01553 8.6e-67 H Methyltransferase domain
HLOPPLNL_01555 1.7e-16 K DNA-templated transcription, initiation
HLOPPLNL_01557 2.2e-08 S Protein of unknown function (DUF2922)
HLOPPLNL_01561 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
HLOPPLNL_01562 1e-27 ysxB J Cysteine protease Prp
HLOPPLNL_01563 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HLOPPLNL_01564 4.7e-09 M LysM domain
HLOPPLNL_01568 1.5e-70
HLOPPLNL_01569 2.4e-101 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HLOPPLNL_01570 2.9e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HLOPPLNL_01571 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HLOPPLNL_01572 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HLOPPLNL_01573 5.9e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HLOPPLNL_01574 3.5e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLOPPLNL_01575 7e-59 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLOPPLNL_01576 3.2e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLOPPLNL_01577 3.4e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HLOPPLNL_01578 2e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLOPPLNL_01579 4.1e-51 yeaL S Protein of unknown function (DUF441)
HLOPPLNL_01580 1.4e-124 cvfB S S1 domain
HLOPPLNL_01581 3.6e-112 xerD D recombinase XerD
HLOPPLNL_01582 1.9e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HLOPPLNL_01583 2.3e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLOPPLNL_01584 3.7e-188 nhaC C Na H antiporter NhaC
HLOPPLNL_01585 1e-64 ypsA S Belongs to the UPF0398 family
HLOPPLNL_01586 2.5e-197 ade 3.5.4.2 F Adenine deaminase C-terminal domain
HLOPPLNL_01588 6.3e-73 2.3.1.178 M GNAT acetyltransferase
HLOPPLNL_01589 1.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
HLOPPLNL_01590 9.7e-57 3.6.1.27 I Acid phosphatase homologues
HLOPPLNL_01591 1.3e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
HLOPPLNL_01593 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HLOPPLNL_01594 1e-202 hsdM 2.1.1.72 V type I restriction-modification system
HLOPPLNL_01595 4.4e-66 hsdS_1 3.1.21.3 V Type I restriction
HLOPPLNL_01596 2.8e-131 L Belongs to the 'phage' integrase family
HLOPPLNL_01597 1.2e-68 3.1.21.3 V Type I restriction modification DNA specificity domain protein
HLOPPLNL_01598 2.5e-92 3.1.21.3 V Type I restriction modification DNA specificity domain
HLOPPLNL_01599 9.8e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLOPPLNL_01600 5.8e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
HLOPPLNL_01601 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HLOPPLNL_01602 7.6e-278 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HLOPPLNL_01603 2e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLOPPLNL_01604 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLOPPLNL_01605 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
HLOPPLNL_01606 1.7e-60 ypbB 5.1.3.1 S Helix-turn-helix domain
HLOPPLNL_01607 3.8e-127 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HLOPPLNL_01608 7.7e-12 M Lysin motif
HLOPPLNL_01609 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HLOPPLNL_01610 4.4e-83 lytH 3.5.1.28 M Ami_3
HLOPPLNL_01611 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
HLOPPLNL_01612 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLOPPLNL_01613 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HLOPPLNL_01614 7.8e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLOPPLNL_01615 2.2e-89 recO L Involved in DNA repair and RecF pathway recombination
HLOPPLNL_01616 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
HLOPPLNL_01617 9e-220 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLOPPLNL_01618 5.9e-174 dltB M MBOAT, membrane-bound O-acyltransferase family
HLOPPLNL_01619 1.4e-28 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLOPPLNL_01620 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLOPPLNL_01621 1.4e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
HLOPPLNL_01622 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
HLOPPLNL_01623 1.3e-227 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HLOPPLNL_01624 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLOPPLNL_01626 3.1e-22 K Acetyltransferase (GNAT) domain
HLOPPLNL_01627 2.4e-111 natA S Domain of unknown function (DUF4162)
HLOPPLNL_01628 2.3e-80 natB CP ABC-type Na efflux pump, permease component
HLOPPLNL_01631 5.1e-08
HLOPPLNL_01639 2.1e-07
HLOPPLNL_01654 8.9e-54 S Membrane
HLOPPLNL_01655 0.0 rafA 3.2.1.22 G alpha-galactosidase
HLOPPLNL_01656 2.6e-58 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
HLOPPLNL_01657 7.7e-39 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HLOPPLNL_01658 1.6e-112 2.7.7.65 T diguanylate cyclase activity
HLOPPLNL_01659 0.0 ydaN S Bacterial cellulose synthase subunit
HLOPPLNL_01660 9e-202 ydaM M Glycosyl transferase family group 2
HLOPPLNL_01661 1e-205 S Protein conserved in bacteria
HLOPPLNL_01662 8.4e-183
HLOPPLNL_01663 8.1e-127 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HLOPPLNL_01664 4e-42 2.7.7.65 T GGDEF domain
HLOPPLNL_01665 3.9e-147 pbuO_1 S Permease family
HLOPPLNL_01666 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
HLOPPLNL_01667 2.9e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HLOPPLNL_01668 1.4e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HLOPPLNL_01669 3.6e-220 cydD CO ABC transporter transmembrane region
HLOPPLNL_01670 4.6e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HLOPPLNL_01671 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HLOPPLNL_01672 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
HLOPPLNL_01673 3.1e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
HLOPPLNL_01674 2.2e-28 xlyB 3.5.1.28 CBM50 M LysM domain
HLOPPLNL_01675 3.9e-19 glpE P Rhodanese Homology Domain
HLOPPLNL_01676 6e-48 lytE M LysM domain protein
HLOPPLNL_01677 1.8e-92 T Calcineurin-like phosphoesterase superfamily domain
HLOPPLNL_01678 3.9e-86 2.7.7.12 C Domain of unknown function (DUF4931)
HLOPPLNL_01680 4.4e-74 draG O ADP-ribosylglycohydrolase
HLOPPLNL_01681 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLOPPLNL_01682 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLOPPLNL_01683 5.1e-62 divIVA D DivIVA domain protein
HLOPPLNL_01684 2.2e-81 ylmH S S4 domain protein
HLOPPLNL_01685 3e-19 yggT S YGGT family
HLOPPLNL_01686 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLOPPLNL_01687 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLOPPLNL_01688 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLOPPLNL_01689 1.9e-62 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLOPPLNL_01690 4e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLOPPLNL_01691 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLOPPLNL_01692 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLOPPLNL_01693 8.4e-280 ftsI 3.4.16.4 M Penicillin-binding Protein
HLOPPLNL_01694 2.5e-11 ftsL D cell division protein FtsL
HLOPPLNL_01695 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLOPPLNL_01696 1.4e-64 mraZ K Belongs to the MraZ family
HLOPPLNL_01697 4.5e-08 S Protein of unknown function (DUF3397)
HLOPPLNL_01698 1.6e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HLOPPLNL_01700 3.7e-99 D Alpha beta
HLOPPLNL_01701 1.8e-108 aatB ET ABC transporter substrate-binding protein
HLOPPLNL_01702 1.4e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HLOPPLNL_01703 1.9e-94 glnP P ABC transporter permease
HLOPPLNL_01704 1.8e-126 minD D Belongs to the ParA family
HLOPPLNL_01705 1.4e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HLOPPLNL_01706 1.2e-54 mreD M rod shape-determining protein MreD
HLOPPLNL_01707 2.1e-88 mreC M Involved in formation and maintenance of cell shape
HLOPPLNL_01708 1.8e-155 mreB D cell shape determining protein MreB
HLOPPLNL_01709 4.5e-21 K Cold shock
HLOPPLNL_01710 9e-79 radC L DNA repair protein
HLOPPLNL_01711 8.1e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HLOPPLNL_01712 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLOPPLNL_01713 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLOPPLNL_01714 1.7e-162 iscS2 2.8.1.7 E Aminotransferase class V
HLOPPLNL_01715 1.2e-172 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLOPPLNL_01716 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
HLOPPLNL_01717 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLOPPLNL_01718 3.4e-24 yueI S Protein of unknown function (DUF1694)
HLOPPLNL_01719 2e-188 rarA L recombination factor protein RarA
HLOPPLNL_01721 3.4e-73 usp6 T universal stress protein
HLOPPLNL_01722 1.8e-53 tag 3.2.2.20 L glycosylase
HLOPPLNL_01725 2e-52 L Probable transposase
HLOPPLNL_01731 6.4e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HLOPPLNL_01732 4.2e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLOPPLNL_01733 1.1e-158 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HLOPPLNL_01734 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HLOPPLNL_01735 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLOPPLNL_01737 1.6e-55 ctsR K Belongs to the CtsR family
HLOPPLNL_01738 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLOPPLNL_01739 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLOPPLNL_01740 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLOPPLNL_01741 3.3e-23 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HLOPPLNL_01742 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLOPPLNL_01743 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLOPPLNL_01744 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLOPPLNL_01745 3.4e-92 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HLOPPLNL_01746 4.4e-89 patB 4.4.1.8 E Aminotransferase, class I
HLOPPLNL_01747 2.5e-113 K response regulator
HLOPPLNL_01748 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
HLOPPLNL_01749 1.6e-88 lacX 5.1.3.3 G Aldose 1-epimerase
HLOPPLNL_01750 3.9e-146 G Transporter, major facilitator family protein
HLOPPLNL_01751 1.5e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLOPPLNL_01752 1.1e-244 yhcA V ABC transporter, ATP-binding protein
HLOPPLNL_01753 7.6e-35 K Bacterial regulatory proteins, tetR family
HLOPPLNL_01754 6.8e-224 lmrA V ABC transporter, ATP-binding protein
HLOPPLNL_01755 3e-254 yfiC V ABC transporter
HLOPPLNL_01757 9.3e-45 yjcF K protein acetylation
HLOPPLNL_01758 1.9e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
HLOPPLNL_01759 1.1e-71 lemA S LemA family
HLOPPLNL_01760 1.3e-114 htpX O Belongs to the peptidase M48B family
HLOPPLNL_01762 1.5e-271 helD 3.6.4.12 L DNA helicase
HLOPPLNL_01763 7.1e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLOPPLNL_01764 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLOPPLNL_01765 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HLOPPLNL_01766 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HLOPPLNL_01767 3.5e-104 ybhR V ABC transporter
HLOPPLNL_01768 2.3e-31 K Transcriptional regulator
HLOPPLNL_01769 2.1e-42 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
HLOPPLNL_01770 6e-153 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HLOPPLNL_01771 5.1e-128
HLOPPLNL_01772 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLOPPLNL_01773 5.9e-103 tatD L hydrolase, TatD family
HLOPPLNL_01774 5.8e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLOPPLNL_01775 2.4e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLOPPLNL_01776 1.2e-22 veg S Biofilm formation stimulator VEG
HLOPPLNL_01777 1.7e-90 S Alpha/beta hydrolase of unknown function (DUF915)
HLOPPLNL_01778 2.7e-133 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
HLOPPLNL_01779 6.6e-46 argR K Regulates arginine biosynthesis genes
HLOPPLNL_01780 3.7e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HLOPPLNL_01781 4.6e-156 amtB P ammonium transporter
HLOPPLNL_01782 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
HLOPPLNL_01783 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLOPPLNL_01784 4e-151 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HLOPPLNL_01785 1.7e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLOPPLNL_01786 1.2e-101 pfoS S Phosphotransferase system, EIIC
HLOPPLNL_01790 2.6e-14 2.7.13.3 T GHKL domain
HLOPPLNL_01791 9.6e-56 K LytTr DNA-binding domain
HLOPPLNL_01796 1.7e-71 xerD L Phage integrase, N-terminal SAM-like domain
HLOPPLNL_01797 2.2e-266 fbp 3.1.3.11 G phosphatase activity
HLOPPLNL_01799 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HLOPPLNL_01800 3.6e-99 fabK 1.3.1.9 S Nitronate monooxygenase
HLOPPLNL_01801 3.7e-22 S Phage minor capsid protein 2
HLOPPLNL_01802 6.5e-09 S Phage Mu protein F like protein
HLOPPLNL_01804 5.5e-13 S YjcQ protein
HLOPPLNL_01808 5.7e-45 M Phage tail tape measure protein TP901
HLOPPLNL_01809 1.6e-116 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HLOPPLNL_01810 9.5e-136 pfoS S Phosphotransferase system, EIIC
HLOPPLNL_01811 2.9e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
HLOPPLNL_01812 5.7e-59 hsdM 2.1.1.72 V type I restriction-modification system
HLOPPLNL_01813 4.9e-250 2.1.1.72 V type I restriction-modification system
HLOPPLNL_01814 3e-48 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HLOPPLNL_01815 1.5e-37 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HLOPPLNL_01816 7.4e-127 xerC L Belongs to the 'phage' integrase family
HLOPPLNL_01817 3.2e-43 3.1.21.3 V Type I restriction modification DNA specificity domain
HLOPPLNL_01818 2e-26 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HLOPPLNL_01819 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HLOPPLNL_01820 7.4e-27 K Helix-turn-helix XRE-family like proteins
HLOPPLNL_01821 1.3e-224 E ABC transporter, substratebinding protein
HLOPPLNL_01822 6.2e-116 sufC O FeS assembly ATPase SufC
HLOPPLNL_01823 4.6e-145 sufD O FeS assembly protein SufD
HLOPPLNL_01824 5.7e-148 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLOPPLNL_01825 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
HLOPPLNL_01826 1.2e-239 sufB O assembly protein SufB
HLOPPLNL_01827 3.3e-45 S VIT family
HLOPPLNL_01828 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HLOPPLNL_01829 7.6e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLOPPLNL_01830 3.6e-112 rssA S Phospholipase, patatin family
HLOPPLNL_01831 1.1e-15
HLOPPLNL_01832 1.9e-29
HLOPPLNL_01833 2.3e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HLOPPLNL_01834 4.6e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HLOPPLNL_01835 7.4e-10 K transcriptional
HLOPPLNL_01836 8.9e-79 yvfR V ABC transporter
HLOPPLNL_01837 1.4e-53 yvfS V ABC-2 type transporter
HLOPPLNL_01838 6.4e-58 salK 2.7.13.3 T Histidine kinase
HLOPPLNL_01839 2e-77 desR K helix_turn_helix, Lux Regulon
HLOPPLNL_01840 4.8e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
HLOPPLNL_01841 6.8e-104 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HLOPPLNL_01844 3.7e-14 S YjcQ protein
HLOPPLNL_01846 3e-63
HLOPPLNL_01847 1.1e-142 xerS L Phage integrase family
HLOPPLNL_01848 6.5e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HLOPPLNL_01849 9.3e-137 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLOPPLNL_01850 6.1e-217 1.3.5.4 C FAD binding domain
HLOPPLNL_01851 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
HLOPPLNL_01852 2.8e-138 G Xylose isomerase-like TIM barrel
HLOPPLNL_01853 7.5e-73 K Transcriptional regulator, LysR family
HLOPPLNL_01854 2.2e-72 EGP Major Facilitator Superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)