ORF_ID e_value Gene_name EC_number CAZy COGs Description
HIIKPMFB_00001 4.1e-46
HIIKPMFB_00002 1.6e-76 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HIIKPMFB_00003 2e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIIKPMFB_00004 2.2e-125 luxT K Bacterial regulatory proteins, tetR family
HIIKPMFB_00005 2.1e-130
HIIKPMFB_00006 1.4e-257 glnPH2 P ABC transporter permease
HIIKPMFB_00007 1.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIIKPMFB_00008 6.6e-229 S Cysteine-rich secretory protein family
HIIKPMFB_00009 4.7e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HIIKPMFB_00010 7.2e-90
HIIKPMFB_00011 4.4e-203 yibE S overlaps another CDS with the same product name
HIIKPMFB_00012 2.4e-131 yibF S overlaps another CDS with the same product name
HIIKPMFB_00013 5.6e-160 I alpha/beta hydrolase fold
HIIKPMFB_00014 0.0 G Belongs to the glycosyl hydrolase 31 family
HIIKPMFB_00015 5.2e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HIIKPMFB_00016 1.8e-89 ntd 2.4.2.6 F Nucleoside
HIIKPMFB_00017 1.1e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HIIKPMFB_00018 2.2e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
HIIKPMFB_00019 1.6e-85 uspA T universal stress protein
HIIKPMFB_00020 1.5e-164 phnD P Phosphonate ABC transporter
HIIKPMFB_00021 2.3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HIIKPMFB_00022 2.8e-132 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HIIKPMFB_00023 7.6e-149 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HIIKPMFB_00024 8.6e-107 tag 3.2.2.20 L glycosylase
HIIKPMFB_00025 1.5e-83
HIIKPMFB_00026 3.4e-274 S Calcineurin-like phosphoesterase
HIIKPMFB_00027 0.0 asnB 6.3.5.4 E Asparagine synthase
HIIKPMFB_00028 3.3e-252 yxbA 6.3.1.12 S ATP-grasp enzyme
HIIKPMFB_00029 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HIIKPMFB_00030 8.1e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HIIKPMFB_00031 6.5e-99 S Iron-sulfur cluster assembly protein
HIIKPMFB_00032 1.1e-233 XK27_04775 S PAS domain
HIIKPMFB_00033 1.1e-228 yttB EGP Major facilitator Superfamily
HIIKPMFB_00034 0.0 pepO 3.4.24.71 O Peptidase family M13
HIIKPMFB_00035 0.0 kup P Transport of potassium into the cell
HIIKPMFB_00036 1.9e-69
HIIKPMFB_00037 6.9e-11
HIIKPMFB_00038 7.9e-212 S SLAP domain
HIIKPMFB_00039 3e-60 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HIIKPMFB_00040 2.4e-256 ica2 GT2 M Glycosyl transferase family group 2
HIIKPMFB_00041 2.2e-175
HIIKPMFB_00042 2.1e-228 S SLAP domain
HIIKPMFB_00043 1.1e-207 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIIKPMFB_00044 7.2e-211 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HIIKPMFB_00045 0.0 yjbQ P TrkA C-terminal domain protein
HIIKPMFB_00046 9.8e-180 S Oxidoreductase family, NAD-binding Rossmann fold
HIIKPMFB_00047 7.4e-141
HIIKPMFB_00048 1.5e-135
HIIKPMFB_00049 2.5e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIIKPMFB_00050 1.8e-110 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HIIKPMFB_00051 1.6e-102 G Aldose 1-epimerase
HIIKPMFB_00052 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HIIKPMFB_00053 6.4e-108 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIIKPMFB_00054 0.0 XK27_08315 M Sulfatase
HIIKPMFB_00055 6.2e-268 S Fibronectin type III domain
HIIKPMFB_00056 3.3e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIIKPMFB_00057 3.3e-56
HIIKPMFB_00059 7.2e-258 pepC 3.4.22.40 E aminopeptidase
HIIKPMFB_00060 1.2e-125 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HIIKPMFB_00061 5e-293 oppA E ABC transporter, substratebinding protein
HIIKPMFB_00062 4.6e-307 oppA E ABC transporter, substratebinding protein
HIIKPMFB_00063 7.5e-211 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIIKPMFB_00064 1.1e-143 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIIKPMFB_00065 4e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIIKPMFB_00066 2.2e-201 oppD P Belongs to the ABC transporter superfamily
HIIKPMFB_00067 1.9e-175 oppF P Belongs to the ABC transporter superfamily
HIIKPMFB_00068 2.3e-256 pepC 3.4.22.40 E aminopeptidase
HIIKPMFB_00069 2.4e-69 hsp O Belongs to the small heat shock protein (HSP20) family
HIIKPMFB_00070 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIIKPMFB_00071 1.3e-114
HIIKPMFB_00073 4.2e-112 E Belongs to the SOS response-associated peptidase family
HIIKPMFB_00074 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIIKPMFB_00075 6.5e-92 comEB 3.5.4.12 F MafB19-like deaminase
HIIKPMFB_00076 3.4e-109 S TPM domain
HIIKPMFB_00077 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HIIKPMFB_00078 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIIKPMFB_00079 3.5e-148 tatD L hydrolase, TatD family
HIIKPMFB_00080 1.6e-92 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HIIKPMFB_00081 1.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HIIKPMFB_00082 3.5e-39 veg S Biofilm formation stimulator VEG
HIIKPMFB_00083 1.6e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HIIKPMFB_00084 1.4e-211 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HIIKPMFB_00085 9.6e-89 S SLAP domain
HIIKPMFB_00086 8.4e-90 S SLAP domain
HIIKPMFB_00087 1.5e-86
HIIKPMFB_00088 7.3e-239 S SLAP domain
HIIKPMFB_00089 1.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIIKPMFB_00090 5.2e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIIKPMFB_00091 7.7e-129 K Helix-turn-helix domain, rpiR family
HIIKPMFB_00092 1.2e-231 ptcC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIIKPMFB_00093 3.3e-169 2.7.1.2 GK ROK family
HIIKPMFB_00094 3.9e-44
HIIKPMFB_00095 7.2e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HIIKPMFB_00096 9.5e-68 S Domain of unknown function (DUF1934)
HIIKPMFB_00097 3.3e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HIIKPMFB_00098 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HIIKPMFB_00099 1.8e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIIKPMFB_00100 1.9e-109 pipD E Dipeptidase
HIIKPMFB_00101 4.4e-160 pipD E Dipeptidase
HIIKPMFB_00102 7.4e-160 msmR K AraC-like ligand binding domain
HIIKPMFB_00103 7e-107 S Protein of unknown function (DUF1211)
HIIKPMFB_00104 5.2e-221 pbuX F xanthine permease
HIIKPMFB_00105 1.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HIIKPMFB_00106 1.5e-135 K DNA-binding helix-turn-helix protein
HIIKPMFB_00107 7.5e-172 K Helix-turn-helix
HIIKPMFB_00108 6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HIIKPMFB_00109 2.5e-155 cylA V ABC transporter
HIIKPMFB_00110 4e-148 cylB V ABC-2 type transporter
HIIKPMFB_00111 1.3e-73 K LytTr DNA-binding domain
HIIKPMFB_00112 2.7e-43 S Protein of unknown function (DUF3021)
HIIKPMFB_00113 1.9e-89 XK27_09675 K Acetyltransferase (GNAT) domain
HIIKPMFB_00114 7e-135 S B3 4 domain
HIIKPMFB_00115 5.4e-90 lmrB P Belongs to the major facilitator superfamily
HIIKPMFB_00116 1.6e-32 P Belongs to the major facilitator superfamily
HIIKPMFB_00117 1.9e-30
HIIKPMFB_00118 7.7e-82 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIIKPMFB_00119 2.5e-28 K NAD+ binding
HIIKPMFB_00121 2.1e-96
HIIKPMFB_00122 3.7e-51
HIIKPMFB_00123 6.7e-44
HIIKPMFB_00124 1.3e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HIIKPMFB_00125 1.1e-300 ybeC E amino acid
HIIKPMFB_00126 3.7e-159 G Sucrose-6F-phosphate phosphohydrolase
HIIKPMFB_00127 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HIIKPMFB_00128 1.9e-39 rpmE2 J Ribosomal protein L31
HIIKPMFB_00129 7.7e-263 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HIIKPMFB_00130 3.9e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HIIKPMFB_00131 7.6e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HIIKPMFB_00132 1.4e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIIKPMFB_00133 5.8e-129 S (CBS) domain
HIIKPMFB_00134 2.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HIIKPMFB_00135 1.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HIIKPMFB_00136 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIIKPMFB_00137 2.4e-34 yabO J S4 domain protein
HIIKPMFB_00138 1.1e-57 divIC D Septum formation initiator
HIIKPMFB_00139 2.8e-63 yabR J S1 RNA binding domain
HIIKPMFB_00140 2.2e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HIIKPMFB_00141 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIIKPMFB_00142 2.6e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HIIKPMFB_00143 1.4e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIIKPMFB_00144 1.5e-302 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HIIKPMFB_00145 7.8e-08
HIIKPMFB_00146 7.8e-08
HIIKPMFB_00148 4.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
HIIKPMFB_00149 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HIIKPMFB_00150 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIIKPMFB_00151 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIIKPMFB_00152 7.9e-123 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HIIKPMFB_00153 1.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HIIKPMFB_00154 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HIIKPMFB_00155 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HIIKPMFB_00156 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HIIKPMFB_00157 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HIIKPMFB_00158 4.6e-106 rplD J Forms part of the polypeptide exit tunnel
HIIKPMFB_00159 1.2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HIIKPMFB_00160 4.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HIIKPMFB_00161 9.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HIIKPMFB_00162 3.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HIIKPMFB_00163 4.9e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HIIKPMFB_00164 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HIIKPMFB_00165 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HIIKPMFB_00166 3.8e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HIIKPMFB_00167 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HIIKPMFB_00168 4.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HIIKPMFB_00169 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HIIKPMFB_00170 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIIKPMFB_00171 9.3e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HIIKPMFB_00172 2.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HIIKPMFB_00173 2.1e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HIIKPMFB_00174 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HIIKPMFB_00175 2.3e-24 rpmD J Ribosomal protein L30
HIIKPMFB_00176 2e-71 rplO J Binds to the 23S rRNA
HIIKPMFB_00177 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HIIKPMFB_00178 2e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HIIKPMFB_00179 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HIIKPMFB_00180 2.7e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HIIKPMFB_00181 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HIIKPMFB_00182 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HIIKPMFB_00183 8.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIIKPMFB_00184 8.2e-61 rplQ J Ribosomal protein L17
HIIKPMFB_00185 2.8e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIIKPMFB_00186 2.4e-161 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIIKPMFB_00187 9.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIIKPMFB_00188 3e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HIIKPMFB_00189 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HIIKPMFB_00190 3.5e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
HIIKPMFB_00191 1e-198 L Phage integrase family
HIIKPMFB_00192 6.5e-27
HIIKPMFB_00193 5.5e-211 repB EP Plasmid replication protein
HIIKPMFB_00194 6.6e-45
HIIKPMFB_00195 3.1e-206 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HIIKPMFB_00196 1.1e-52
HIIKPMFB_00198 0.0 V Type II restriction enzyme, methylase subunits
HIIKPMFB_00199 6.9e-65 S YjcQ protein
HIIKPMFB_00200 1.7e-13
HIIKPMFB_00201 2.8e-11
HIIKPMFB_00202 2.5e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HIIKPMFB_00203 2.5e-118 3.1.3.102, 3.1.3.104, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HIIKPMFB_00204 5.8e-111 S membrane transporter protein
HIIKPMFB_00205 4.7e-128 pgm3 5.4.2.11 G Belongs to the phosphoglycerate mutase family
HIIKPMFB_00206 2.1e-163 czcD P cation diffusion facilitator family transporter
HIIKPMFB_00207 2.2e-19
HIIKPMFB_00208 2.4e-80 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIIKPMFB_00209 6.4e-184 S AAA domain
HIIKPMFB_00210 1.9e-266 pepC 3.4.22.40 E Peptidase C1-like family
HIIKPMFB_00211 7e-52
HIIKPMFB_00212 9.5e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HIIKPMFB_00213 9.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HIIKPMFB_00214 9.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIIKPMFB_00215 6.8e-278 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIIKPMFB_00216 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HIIKPMFB_00217 1.6e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIIKPMFB_00218 3.5e-94 sigH K Belongs to the sigma-70 factor family
HIIKPMFB_00219 2.2e-34
HIIKPMFB_00220 3.5e-114
HIIKPMFB_00221 3.7e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HIIKPMFB_00222 8.1e-173 K helix_turn_helix, arabinose operon control protein
HIIKPMFB_00223 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIIKPMFB_00224 7.8e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HIIKPMFB_00225 6.2e-102 nusG K Participates in transcription elongation, termination and antitermination
HIIKPMFB_00226 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HIIKPMFB_00227 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HIIKPMFB_00228 1.5e-158 pstS P Phosphate
HIIKPMFB_00229 5.2e-176 pstC P probably responsible for the translocation of the substrate across the membrane
HIIKPMFB_00230 2.6e-155 pstA P Phosphate transport system permease protein PstA
HIIKPMFB_00231 4.2e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIIKPMFB_00232 7e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIIKPMFB_00233 2e-118 phoU P Plays a role in the regulation of phosphate uptake
HIIKPMFB_00234 2.2e-210 yfdV S Membrane transport protein
HIIKPMFB_00235 2.2e-10
HIIKPMFB_00236 1.6e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HIIKPMFB_00237 2.2e-47 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HIIKPMFB_00238 1.5e-123 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HIIKPMFB_00239 6.4e-116 rsmC 2.1.1.172 J Methyltransferase
HIIKPMFB_00240 1.4e-23
HIIKPMFB_00241 6.9e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HIIKPMFB_00242 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIIKPMFB_00243 8.1e-60 G polysaccharide catabolic process
HIIKPMFB_00244 0.0 3.2.1.40 G Alpha-L-rhamnosidase N-terminal domain
HIIKPMFB_00245 2.1e-174 rbsR K helix_turn _helix lactose operon repressor
HIIKPMFB_00246 1.3e-216 uhpT EGP Major facilitator Superfamily
HIIKPMFB_00247 4.7e-309 2.7.7.7 S Domain of unknown function (DUF5060)
HIIKPMFB_00248 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HIIKPMFB_00249 4.3e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HIIKPMFB_00250 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HIIKPMFB_00251 1.2e-188 lacR K Transcriptional regulator
HIIKPMFB_00252 2.1e-224 L Putative transposase DNA-binding domain
HIIKPMFB_00253 0.0 lacS G Transporter
HIIKPMFB_00254 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HIIKPMFB_00255 8.8e-113
HIIKPMFB_00256 2.3e-187 M domain protein
HIIKPMFB_00257 2.3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HIIKPMFB_00258 4.3e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HIIKPMFB_00259 3.2e-194 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HIIKPMFB_00260 1.8e-167 S SLAP domain
HIIKPMFB_00261 1.1e-39 C FMN binding
HIIKPMFB_00263 1.2e-45
HIIKPMFB_00264 5.3e-52 S Domain of unknown function (DUF4160)
HIIKPMFB_00265 1.1e-96 S Domain of unknown function (DUF4811)
HIIKPMFB_00266 1.6e-266 lmrB EGP Major facilitator Superfamily
HIIKPMFB_00267 5e-75 merR K MerR HTH family regulatory protein
HIIKPMFB_00268 3.7e-159 msmR K helix_turn_helix, arabinose operon control protein
HIIKPMFB_00269 4e-242 msmE G Bacterial extracellular solute-binding protein
HIIKPMFB_00270 1.8e-156 msmF P Binding-protein-dependent transport system inner membrane component
HIIKPMFB_00271 1.5e-152 msmG P Binding-protein-dependent transport system inner membrane component
HIIKPMFB_00272 2.3e-209 msmX P Belongs to the ABC transporter superfamily
HIIKPMFB_00273 0.0 rafA 3.2.1.22 G alpha-galactosidase
HIIKPMFB_00274 1.6e-282 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HIIKPMFB_00275 5.6e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HIIKPMFB_00276 2.1e-61 dhaM 2.7.1.121 S PTS system fructose IIA component
HIIKPMFB_00277 1.2e-103 dhaL 2.7.1.121 S Dak2
HIIKPMFB_00278 2.3e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HIIKPMFB_00279 1.7e-113 2.7.6.5 T Region found in RelA / SpoT proteins
HIIKPMFB_00280 1.5e-118 K response regulator
HIIKPMFB_00281 1.2e-233 sptS 2.7.13.3 T Histidine kinase
HIIKPMFB_00282 1.8e-212 EGP Major facilitator Superfamily
HIIKPMFB_00283 9.2e-71 O OsmC-like protein
HIIKPMFB_00284 9e-127 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
HIIKPMFB_00285 2.4e-128
HIIKPMFB_00287 2.4e-127 S Alpha beta hydrolase
HIIKPMFB_00288 1.1e-278 yjeM E Amino Acid
HIIKPMFB_00289 2.9e-13
HIIKPMFB_00290 4e-109 pncA Q Isochorismatase family
HIIKPMFB_00291 6e-27 C pentaerythritol trinitrate reductase activity
HIIKPMFB_00292 9.3e-214 L TIGRFAM transposase, IS605 OrfB family
HIIKPMFB_00293 8.1e-09 L Probable transposase
HIIKPMFB_00294 5.7e-177 C Oxidoreductase
HIIKPMFB_00295 1e-90
HIIKPMFB_00296 1.5e-244 pgaC GT2 M Glycosyl transferase
HIIKPMFB_00297 3.6e-143 T EAL domain
HIIKPMFB_00298 1e-130 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HIIKPMFB_00299 2e-208 2.7.7.65 T GGDEF domain
HIIKPMFB_00302 0.0 1.3.5.4 C FMN_bind
HIIKPMFB_00303 3.4e-160 K Bacterial regulatory helix-turn-helix protein, lysR family
HIIKPMFB_00305 1.1e-118 S GyrI-like small molecule binding domain
HIIKPMFB_00306 2.4e-65 S ASCH domain
HIIKPMFB_00307 1.7e-57 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HIIKPMFB_00308 1.5e-115 ylbE GM NAD(P)H-binding
HIIKPMFB_00309 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HIIKPMFB_00310 3.9e-62 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HIIKPMFB_00311 9.1e-264 npr 1.11.1.1 C NADH oxidase
HIIKPMFB_00313 0.0 oppA E ABC transporter substrate-binding protein
HIIKPMFB_00314 5.7e-52 S Iron-sulfur cluster assembly protein
HIIKPMFB_00315 9e-156 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HIIKPMFB_00316 8.1e-125 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HIIKPMFB_00317 8.8e-47
HIIKPMFB_00318 1.5e-147 metQ2 P Belongs to the nlpA lipoprotein family
HIIKPMFB_00319 1e-50
HIIKPMFB_00320 8.8e-95 wecD K acetyltransferase
HIIKPMFB_00321 0.0 UW LPXTG-motif cell wall anchor domain protein
HIIKPMFB_00322 5.2e-103 O Matrixin
HIIKPMFB_00323 1.8e-248 clcA P chloride
HIIKPMFB_00324 0.0 3.6.3.8 P P-type ATPase
HIIKPMFB_00325 1.2e-117 GM NmrA-like family
HIIKPMFB_00326 6.4e-119 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HIIKPMFB_00327 1.5e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HIIKPMFB_00328 9.8e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HIIKPMFB_00329 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIIKPMFB_00330 8.5e-184 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HIIKPMFB_00331 6.1e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HIIKPMFB_00332 7.1e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HIIKPMFB_00333 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HIIKPMFB_00335 0.0
HIIKPMFB_00336 6.6e-151 glcU U sugar transport
HIIKPMFB_00337 4.9e-47
HIIKPMFB_00338 8.1e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HIIKPMFB_00339 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HIIKPMFB_00340 2.3e-47 S Motility quorum-sensing regulator, toxin of MqsA
HIIKPMFB_00341 4.2e-65 ps301 K sequence-specific DNA binding
HIIKPMFB_00342 3.4e-16
HIIKPMFB_00343 6.4e-100 S Bacterial PH domain
HIIKPMFB_00344 1.8e-237 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIIKPMFB_00345 7.3e-206 xylR GK ROK family
HIIKPMFB_00346 1.1e-166 bglK 2.7.1.2, 2.7.1.85 GK ROK family
HIIKPMFB_00347 7.7e-309 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIIKPMFB_00348 0.0 yic1 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
HIIKPMFB_00349 0.0 lacA 3.2.1.23 G -beta-galactosidase
HIIKPMFB_00350 1.2e-163
HIIKPMFB_00351 1.8e-206
HIIKPMFB_00352 1.5e-152 S haloacid dehalogenase-like hydrolase
HIIKPMFB_00353 8.5e-290 V ABC-type multidrug transport system, ATPase and permease components
HIIKPMFB_00354 5.2e-295 V ABC-type multidrug transport system, ATPase and permease components
HIIKPMFB_00355 1e-65 arsC 1.20.4.1 P Belongs to the ArsC family
HIIKPMFB_00356 6.5e-178 I Carboxylesterase family
HIIKPMFB_00357 1.7e-165 S Membrane
HIIKPMFB_00359 1.6e-74 M Glycosyl hydrolases family 25
HIIKPMFB_00360 1.7e-115 M Glycosyl hydrolases family 25
HIIKPMFB_00361 3.6e-154 cinI S Serine hydrolase (FSH1)
HIIKPMFB_00362 5e-311 S Predicted membrane protein (DUF2207)
HIIKPMFB_00363 3.7e-153 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
HIIKPMFB_00364 9.2e-98 E ABC transporter
HIIKPMFB_00365 6.7e-60 oppA E ABC transporter
HIIKPMFB_00367 3.2e-109 Q Imidazolonepropionase and related amidohydrolases
HIIKPMFB_00368 1.3e-105 Q Imidazolonepropionase and related amidohydrolases
HIIKPMFB_00369 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HIIKPMFB_00370 1.8e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HIIKPMFB_00371 6.8e-259 S Uncharacterized protein conserved in bacteria (DUF2325)
HIIKPMFB_00372 2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIIKPMFB_00373 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HIIKPMFB_00374 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HIIKPMFB_00375 3.2e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HIIKPMFB_00376 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIIKPMFB_00377 6.8e-72 yqhY S Asp23 family, cell envelope-related function
HIIKPMFB_00378 3.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HIIKPMFB_00379 1.9e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HIIKPMFB_00380 7.3e-213 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIIKPMFB_00381 3.4e-36 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIIKPMFB_00382 6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HIIKPMFB_00383 3.5e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HIIKPMFB_00384 4.7e-310 recN L May be involved in recombinational repair of damaged DNA
HIIKPMFB_00385 1.8e-80 6.3.3.2 S ASCH
HIIKPMFB_00386 1.5e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HIIKPMFB_00387 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HIIKPMFB_00388 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIIKPMFB_00389 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HIIKPMFB_00390 1.3e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HIIKPMFB_00391 2.3e-139 stp 3.1.3.16 T phosphatase
HIIKPMFB_00392 0.0 KLT serine threonine protein kinase
HIIKPMFB_00393 8e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HIIKPMFB_00394 4.5e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HIIKPMFB_00395 6.9e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
HIIKPMFB_00396 4.2e-52
HIIKPMFB_00397 3.7e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HIIKPMFB_00398 6.8e-57 asp S Asp23 family, cell envelope-related function
HIIKPMFB_00399 2.4e-306 yloV S DAK2 domain fusion protein YloV
HIIKPMFB_00400 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HIIKPMFB_00401 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HIIKPMFB_00402 5.7e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIIKPMFB_00403 2.5e-197 oppD P Belongs to the ABC transporter superfamily
HIIKPMFB_00404 6.1e-177 oppF P Belongs to the ABC transporter superfamily
HIIKPMFB_00405 2.3e-176 oppB P ABC transporter permease
HIIKPMFB_00406 2.9e-144 oppC P Binding-protein-dependent transport system inner membrane component
HIIKPMFB_00407 0.0 oppA E ABC transporter substrate-binding protein
HIIKPMFB_00408 0.0 oppA E ABC transporter substrate-binding protein
HIIKPMFB_00409 6.6e-30 L COG2963 Transposase and inactivated derivatives
HIIKPMFB_00412 9.7e-132 K response regulator
HIIKPMFB_00413 5.3e-307 vicK 2.7.13.3 T Histidine kinase
HIIKPMFB_00414 1e-259 yycH S YycH protein
HIIKPMFB_00415 9.4e-147 yycI S YycH protein
HIIKPMFB_00416 1.1e-149 vicX 3.1.26.11 S domain protein
HIIKPMFB_00417 8.8e-149 htrA 3.4.21.107 O serine protease
HIIKPMFB_00418 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HIIKPMFB_00419 2.4e-150 K Helix-turn-helix XRE-family like proteins
HIIKPMFB_00421 2.1e-258 S CAAX protease self-immunity
HIIKPMFB_00422 4.5e-18
HIIKPMFB_00423 1.1e-121
HIIKPMFB_00424 1.3e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HIIKPMFB_00425 8.9e-92 P Cobalt transport protein
HIIKPMFB_00426 6e-252 cbiO1 S ABC transporter, ATP-binding protein
HIIKPMFB_00427 3.9e-173 K helix_turn_helix, arabinose operon control protein
HIIKPMFB_00428 1.6e-163 htpX O Belongs to the peptidase M48B family
HIIKPMFB_00429 1.4e-93 lemA S LemA family
HIIKPMFB_00430 2.5e-195 ybiR P Citrate transporter
HIIKPMFB_00431 2.2e-69 S Iron-sulphur cluster biosynthesis
HIIKPMFB_00432 1.1e-301 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HIIKPMFB_00433 1.2e-17
HIIKPMFB_00434 1.6e-152
HIIKPMFB_00436 1.6e-228 ydaM M Glycosyl transferase family group 2
HIIKPMFB_00437 1.5e-211 G Glycosyl hydrolases family 8
HIIKPMFB_00438 3.7e-122 yfbR S HD containing hydrolase-like enzyme
HIIKPMFB_00439 4e-161 L HNH nucleases
HIIKPMFB_00440 1.2e-182 S Protein of unknown function (DUF805)
HIIKPMFB_00441 2.1e-137 glnQ E ABC transporter, ATP-binding protein
HIIKPMFB_00442 1e-293 glnP P ABC transporter permease
HIIKPMFB_00443 5.5e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HIIKPMFB_00444 2.5e-64 yeaO S Protein of unknown function, DUF488
HIIKPMFB_00445 5.8e-138 terC P Integral membrane protein TerC family
HIIKPMFB_00446 2.3e-133 cobB K SIR2 family
HIIKPMFB_00447 1.7e-84
HIIKPMFB_00448 1.2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIIKPMFB_00449 1.9e-180 S Alpha/beta hydrolase of unknown function (DUF915)
HIIKPMFB_00450 2.2e-142 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIIKPMFB_00451 7.7e-137 ypuA S Protein of unknown function (DUF1002)
HIIKPMFB_00452 7.3e-160 2.4.1.293 GT2 M Glycosyltransferase like family 2
HIIKPMFB_00453 5.6e-126 S Alpha/beta hydrolase family
HIIKPMFB_00454 8.3e-148 K Helix-turn-helix XRE-family like proteins
HIIKPMFB_00455 2.9e-51
HIIKPMFB_00456 1.4e-295 V ABC-type multidrug transport system, ATPase and permease components
HIIKPMFB_00457 2.8e-288 P ABC transporter
HIIKPMFB_00458 3e-78
HIIKPMFB_00459 2.1e-148 arbV 2.3.1.51 I Acyl-transferase
HIIKPMFB_00460 1.1e-158 arbx M Glycosyl transferase family 8
HIIKPMFB_00461 2.2e-187 arbY M Glycosyl transferase family 8
HIIKPMFB_00462 8.4e-184 arbY M Glycosyl transferase family 8
HIIKPMFB_00463 5e-167 arbZ I Phosphate acyltransferases
HIIKPMFB_00464 1.5e-38 S Cytochrome B5
HIIKPMFB_00465 5.6e-115 K Transcriptional regulator, LysR family
HIIKPMFB_00466 2.6e-230 1.3.5.4 C FAD binding domain
HIIKPMFB_00467 4.2e-56 1.3.5.4 S FMN_bind
HIIKPMFB_00468 2.2e-51 K LysR substrate binding domain
HIIKPMFB_00469 2e-33 K LysR substrate binding domain
HIIKPMFB_00470 7.1e-122
HIIKPMFB_00471 3.2e-205 cycA E Amino acid permease
HIIKPMFB_00472 3.6e-220 yifK E Amino acid permease
HIIKPMFB_00473 8e-142 puuD S peptidase C26
HIIKPMFB_00474 1.7e-241 steT_1 E amino acid
HIIKPMFB_00475 1.1e-52 yusE CO Thioredoxin
HIIKPMFB_00477 3.6e-117 M1-798 K Rhodanese Homology Domain
HIIKPMFB_00478 1.3e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIIKPMFB_00479 1.1e-118 frnE Q DSBA-like thioredoxin domain
HIIKPMFB_00480 3e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
HIIKPMFB_00481 1.5e-202 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HIIKPMFB_00484 2e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIIKPMFB_00485 3.2e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HIIKPMFB_00486 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIIKPMFB_00487 1.5e-56
HIIKPMFB_00488 3.1e-105
HIIKPMFB_00489 1.6e-163 yicL EG EamA-like transporter family
HIIKPMFB_00490 3.2e-167 EG EamA-like transporter family
HIIKPMFB_00491 1.6e-166 EG EamA-like transporter family
HIIKPMFB_00492 9.5e-83 M NlpC/P60 family
HIIKPMFB_00493 7.6e-134 cobQ S glutamine amidotransferase
HIIKPMFB_00494 2.2e-170 L transposase, IS605 OrfB family
HIIKPMFB_00495 3.3e-57 S Protein conserved in bacteria
HIIKPMFB_00496 2.4e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HIIKPMFB_00497 1.4e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HIIKPMFB_00498 3.4e-16
HIIKPMFB_00499 5e-75
HIIKPMFB_00500 6.8e-295 V ABC transporter transmembrane region
HIIKPMFB_00501 6.7e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
HIIKPMFB_00502 4.8e-179 yvdE K helix_turn _helix lactose operon repressor
HIIKPMFB_00503 9.4e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIIKPMFB_00504 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HIIKPMFB_00505 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HIIKPMFB_00506 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HIIKPMFB_00507 9.6e-118 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HIIKPMFB_00508 1.8e-74 tnpB L Putative transposase DNA-binding domain
HIIKPMFB_00509 1.7e-289 G isomerase
HIIKPMFB_00510 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIIKPMFB_00511 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HIIKPMFB_00512 2.7e-277 rbsA 3.6.3.17 G ABC transporter
HIIKPMFB_00514 2e-147 rbsC U Belongs to the binding-protein-dependent transport system permease family
HIIKPMFB_00515 5.7e-175 rbsB G Periplasmic binding protein domain
HIIKPMFB_00516 2.4e-258 G Protein of unknown function (DUF4038)
HIIKPMFB_00517 5.7e-155 licT K CAT RNA binding domain
HIIKPMFB_00518 0.0 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIIKPMFB_00519 7.3e-177 I alpha/beta hydrolase fold
HIIKPMFB_00520 1e-78 G YdjC-like protein
HIIKPMFB_00521 7.4e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HIIKPMFB_00522 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HIIKPMFB_00523 7.5e-25 secG U Preprotein translocase
HIIKPMFB_00524 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIIKPMFB_00525 4.7e-180 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIIKPMFB_00526 2.9e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
HIIKPMFB_00527 2.3e-223 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HIIKPMFB_00539 1.6e-45 L Helicase C-terminal domain protein
HIIKPMFB_00540 0.0 L Helicase C-terminal domain protein
HIIKPMFB_00541 7.1e-74 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HIIKPMFB_00558 1.5e-228 potE E amino acid
HIIKPMFB_00559 1.1e-130 M Glycosyl hydrolases family 25
HIIKPMFB_00560 2.6e-209 yfmL 3.6.4.13 L DEAD DEAH box helicase
HIIKPMFB_00561 1.2e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIIKPMFB_00564 4.1e-217 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HIIKPMFB_00565 4.3e-89 gtcA S Teichoic acid glycosylation protein
HIIKPMFB_00566 1.2e-79 fld C Flavodoxin
HIIKPMFB_00567 1.1e-163 map 3.4.11.18 E Methionine Aminopeptidase
HIIKPMFB_00568 4.1e-151 yihY S Belongs to the UPF0761 family
HIIKPMFB_00569 3.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HIIKPMFB_00570 5.1e-215 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HIIKPMFB_00571 4.6e-219 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HIIKPMFB_00572 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HIIKPMFB_00573 1.9e-46
HIIKPMFB_00574 1.5e-177 D Alpha beta
HIIKPMFB_00575 6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIIKPMFB_00576 1.7e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
HIIKPMFB_00577 9.1e-86
HIIKPMFB_00578 1.2e-71
HIIKPMFB_00579 9.5e-158 hlyX S Transporter associated domain
HIIKPMFB_00580 1e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HIIKPMFB_00581 6.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
HIIKPMFB_00582 0.0 clpE O Belongs to the ClpA ClpB family
HIIKPMFB_00583 8.5e-41 ptsH G phosphocarrier protein HPR
HIIKPMFB_00584 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIIKPMFB_00585 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HIIKPMFB_00586 8.8e-128 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HIIKPMFB_00587 1.4e-161 coiA 3.6.4.12 S Competence protein
HIIKPMFB_00588 1.2e-114 yjbH Q Thioredoxin
HIIKPMFB_00589 9.5e-112 yjbK S CYTH
HIIKPMFB_00590 2.3e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
HIIKPMFB_00591 1.6e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIIKPMFB_00592 8.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIIKPMFB_00593 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HIIKPMFB_00594 2e-118 S SNARE associated Golgi protein
HIIKPMFB_00595 1.7e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HIIKPMFB_00596 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HIIKPMFB_00597 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HIIKPMFB_00598 3.2e-212 yubA S AI-2E family transporter
HIIKPMFB_00599 1.3e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HIIKPMFB_00600 1.8e-68 WQ51_03320 S Protein of unknown function (DUF1149)
HIIKPMFB_00601 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HIIKPMFB_00602 3.5e-227 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HIIKPMFB_00603 4.5e-241 S Peptidase M16
HIIKPMFB_00604 2e-132 IQ Enoyl-(Acyl carrier protein) reductase
HIIKPMFB_00605 6.6e-119 ymfM S Helix-turn-helix domain
HIIKPMFB_00606 9.3e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIIKPMFB_00607 7.9e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIIKPMFB_00608 1e-221 rny S Endoribonuclease that initiates mRNA decay
HIIKPMFB_00609 1.8e-212 tagO 2.7.8.33, 2.7.8.35 M transferase
HIIKPMFB_00610 9.6e-118 yvyE 3.4.13.9 S YigZ family
HIIKPMFB_00611 3.3e-247 comFA L Helicase C-terminal domain protein
HIIKPMFB_00612 3.1e-135 comFC S Competence protein
HIIKPMFB_00613 5.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HIIKPMFB_00614 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HIIKPMFB_00615 3.5e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HIIKPMFB_00617 5.4e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HIIKPMFB_00618 1.4e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HIIKPMFB_00619 6.1e-188 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HIIKPMFB_00620 1.2e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIIKPMFB_00621 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HIIKPMFB_00622 2.9e-223 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HIIKPMFB_00623 7.2e-214 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HIIKPMFB_00624 2.8e-287 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HIIKPMFB_00625 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HIIKPMFB_00626 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HIIKPMFB_00627 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HIIKPMFB_00628 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HIIKPMFB_00629 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HIIKPMFB_00630 1.1e-90 S Short repeat of unknown function (DUF308)
HIIKPMFB_00631 4.8e-165 rapZ S Displays ATPase and GTPase activities
HIIKPMFB_00632 8.1e-196 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HIIKPMFB_00633 6.8e-170 whiA K May be required for sporulation
HIIKPMFB_00634 4.7e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HIIKPMFB_00635 0.0 S SH3-like domain
HIIKPMFB_00636 1.3e-276 ycaM E amino acid
HIIKPMFB_00638 8.6e-190 cggR K Putative sugar-binding domain
HIIKPMFB_00639 3.8e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIIKPMFB_00640 3.5e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HIIKPMFB_00641 9.9e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIIKPMFB_00642 1.3e-96
HIIKPMFB_00643 3.1e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
HIIKPMFB_00644 2.6e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HIIKPMFB_00645 1.8e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HIIKPMFB_00646 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HIIKPMFB_00647 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
HIIKPMFB_00648 2.4e-164 murB 1.3.1.98 M Cell wall formation
HIIKPMFB_00649 9.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HIIKPMFB_00650 1.1e-136 potB P ABC transporter permease
HIIKPMFB_00651 2.9e-132 potC P ABC transporter permease
HIIKPMFB_00652 1e-206 potD P ABC transporter
HIIKPMFB_00653 1.1e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIIKPMFB_00654 1.2e-172 ybbR S YbbR-like protein
HIIKPMFB_00655 3.9e-259 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIIKPMFB_00656 1.3e-148 S hydrolase
HIIKPMFB_00657 1.3e-145 S Sucrose-6F-phosphate phosphohydrolase
HIIKPMFB_00658 1e-120
HIIKPMFB_00659 1.7e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIIKPMFB_00660 6.7e-212 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HIIKPMFB_00661 3.4e-152 licT K CAT RNA binding domain
HIIKPMFB_00662 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIIKPMFB_00663 3.1e-286 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIIKPMFB_00664 4.2e-175 D Alpha beta
HIIKPMFB_00665 0.0 E Amino acid permease
HIIKPMFB_00667 2.2e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIIKPMFB_00668 1.9e-92 S VanZ like family
HIIKPMFB_00669 2e-132 yebC K Transcriptional regulatory protein
HIIKPMFB_00670 5.4e-178 comGA NU Type II IV secretion system protein
HIIKPMFB_00671 9.9e-175 comGB NU type II secretion system
HIIKPMFB_00672 2.4e-46 comGC U competence protein ComGC
HIIKPMFB_00673 2e-71
HIIKPMFB_00674 1e-19
HIIKPMFB_00675 1.3e-86 comGF U Putative Competence protein ComGF
HIIKPMFB_00676 3e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
HIIKPMFB_00677 2.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIIKPMFB_00679 4.3e-121 M Protein of unknown function (DUF3737)
HIIKPMFB_00680 8.1e-176 patB 4.4.1.8 E Aminotransferase, class I
HIIKPMFB_00681 5.7e-29 4.4.1.8 E Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HIIKPMFB_00682 2.3e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
HIIKPMFB_00683 4.9e-61 S SdpI/YhfL protein family
HIIKPMFB_00684 2.2e-131 K Transcriptional regulatory protein, C terminal
HIIKPMFB_00685 6.2e-271 T PhoQ Sensor
HIIKPMFB_00686 1.6e-61 limB 1.14.13.107, 1.14.13.162 C Luciferase-like monooxygenase
HIIKPMFB_00687 2.2e-123 XK27_00915 C Luciferase-like monooxygenase
HIIKPMFB_00688 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIIKPMFB_00689 4.1e-107 vanZ V VanZ like family
HIIKPMFB_00690 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
HIIKPMFB_00691 9.9e-250 EGP Major facilitator Superfamily
HIIKPMFB_00692 1.6e-196 ampC V Beta-lactamase
HIIKPMFB_00695 2e-64
HIIKPMFB_00696 2.9e-287 S DNA primase
HIIKPMFB_00697 1.6e-35
HIIKPMFB_00698 1.9e-33
HIIKPMFB_00699 8.1e-69
HIIKPMFB_00700 1.4e-36
HIIKPMFB_00701 2.9e-12 S Helix-turn-helix domain
HIIKPMFB_00702 3.2e-58 K Transcriptional
HIIKPMFB_00703 9.5e-208 sip L Belongs to the 'phage' integrase family
HIIKPMFB_00704 2e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HIIKPMFB_00705 4.5e-114 tdk 2.7.1.21 F thymidine kinase
HIIKPMFB_00706 3.4e-181 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HIIKPMFB_00707 7.8e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HIIKPMFB_00708 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HIIKPMFB_00709 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HIIKPMFB_00710 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HIIKPMFB_00711 6.6e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIIKPMFB_00712 1.7e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HIIKPMFB_00713 1.5e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIIKPMFB_00714 4.3e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HIIKPMFB_00715 9.8e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HIIKPMFB_00716 2.1e-255 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HIIKPMFB_00717 6.9e-64 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HIIKPMFB_00718 2.6e-30 ywzB S Protein of unknown function (DUF1146)
HIIKPMFB_00719 1.9e-178 mbl D Cell shape determining protein MreB Mrl
HIIKPMFB_00720 2.5e-49 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HIIKPMFB_00721 1.5e-33 S Protein of unknown function (DUF2969)
HIIKPMFB_00722 9.5e-217 rodA D Belongs to the SEDS family
HIIKPMFB_00723 5.8e-77 uspA T universal stress protein
HIIKPMFB_00724 4e-33
HIIKPMFB_00725 4.2e-242 rarA L recombination factor protein RarA
HIIKPMFB_00726 1.9e-83 yueI S Protein of unknown function (DUF1694)
HIIKPMFB_00727 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HIIKPMFB_00728 1.5e-292 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HIIKPMFB_00729 1.1e-217 iscS2 2.8.1.7 E Aminotransferase class V
HIIKPMFB_00730 5.9e-230 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIIKPMFB_00731 2.2e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HIIKPMFB_00732 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HIIKPMFB_00733 8.5e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HIIKPMFB_00734 8.9e-127 S Haloacid dehalogenase-like hydrolase
HIIKPMFB_00735 1.2e-114 radC L DNA repair protein
HIIKPMFB_00736 1.1e-176 mreB D cell shape determining protein MreB
HIIKPMFB_00737 7.2e-150 mreC M Involved in formation and maintenance of cell shape
HIIKPMFB_00738 7.1e-95 mreD
HIIKPMFB_00739 8.8e-10 S Protein of unknown function (DUF4044)
HIIKPMFB_00740 3.2e-53 S Protein of unknown function (DUF3397)
HIIKPMFB_00741 4e-72 mraZ K Belongs to the MraZ family
HIIKPMFB_00742 2.2e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HIIKPMFB_00743 2.4e-54 ftsL D Cell division protein FtsL
HIIKPMFB_00744 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HIIKPMFB_00745 2.1e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HIIKPMFB_00746 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HIIKPMFB_00747 4e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HIIKPMFB_00748 1.2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HIIKPMFB_00749 2.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HIIKPMFB_00750 4.2e-245 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIIKPMFB_00751 2.1e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HIIKPMFB_00752 7.8e-29 yggT S YGGT family
HIIKPMFB_00753 6.7e-150 ylmH S S4 domain protein
HIIKPMFB_00754 1.9e-75 gpsB D DivIVA domain protein
HIIKPMFB_00755 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HIIKPMFB_00756 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
HIIKPMFB_00757 8.9e-104 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HIIKPMFB_00758 3.4e-28
HIIKPMFB_00759 5.9e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIIKPMFB_00760 9.8e-58 XK27_04120 S Putative amino acid metabolism
HIIKPMFB_00761 9.3e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HIIKPMFB_00762 4.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HIIKPMFB_00763 5.7e-115 S Repeat protein
HIIKPMFB_00764 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HIIKPMFB_00765 3.7e-304 L Nuclease-related domain
HIIKPMFB_00766 9.3e-183 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HIIKPMFB_00767 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIIKPMFB_00768 3.2e-33 ykzG S Belongs to the UPF0356 family
HIIKPMFB_00769 1.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIIKPMFB_00770 0.0 typA T GTP-binding protein TypA
HIIKPMFB_00771 7.7e-211 ftsW D Belongs to the SEDS family
HIIKPMFB_00772 4.3e-53 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HIIKPMFB_00773 4.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HIIKPMFB_00774 6.2e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HIIKPMFB_00775 7.6e-194 ylbL T Belongs to the peptidase S16 family
HIIKPMFB_00776 1.7e-72 comEA L Competence protein ComEA
HIIKPMFB_00777 0.0 comEC S Competence protein ComEC
HIIKPMFB_00778 8.8e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
HIIKPMFB_00779 3e-35 rpsT J Binds directly to 16S ribosomal RNA
HIIKPMFB_00780 1.1e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HIIKPMFB_00781 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIIKPMFB_00782 2.2e-151
HIIKPMFB_00783 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HIIKPMFB_00784 3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HIIKPMFB_00785 1.2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HIIKPMFB_00786 2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HIIKPMFB_00787 8.9e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HIIKPMFB_00788 2.5e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
HIIKPMFB_00789 2.9e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HIIKPMFB_00790 5.7e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HIIKPMFB_00791 2.8e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HIIKPMFB_00792 3.7e-176 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIIKPMFB_00793 3.9e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HIIKPMFB_00794 5.3e-220 aspC 2.6.1.1 E Aminotransferase
HIIKPMFB_00795 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIIKPMFB_00796 9.2e-206 pbpX1 V Beta-lactamase
HIIKPMFB_00797 1.3e-298 I Protein of unknown function (DUF2974)
HIIKPMFB_00798 8.6e-41 C FMN_bind
HIIKPMFB_00799 1.6e-80
HIIKPMFB_00800 1.9e-286
HIIKPMFB_00801 5.2e-178 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HIIKPMFB_00802 8.5e-145
HIIKPMFB_00803 2.7e-10
HIIKPMFB_00806 6.1e-19 alkD L DNA alkylation repair enzyme
HIIKPMFB_00807 1.5e-67 alkD L DNA alkylation repair enzyme
HIIKPMFB_00808 6e-39 S Transglycosylase associated protein
HIIKPMFB_00810 2.4e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIIKPMFB_00811 2.2e-128 K UTRA domain
HIIKPMFB_00812 4.5e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HIIKPMFB_00813 6.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HIIKPMFB_00814 1.2e-80
HIIKPMFB_00815 4.4e-138 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIIKPMFB_00816 1.2e-70 S Domain of unknown function (DUF3284)
HIIKPMFB_00817 6.3e-303 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIIKPMFB_00818 4.7e-134 gmuR K UTRA
HIIKPMFB_00819 3.5e-41
HIIKPMFB_00820 2.4e-267 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIIKPMFB_00821 9.5e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIIKPMFB_00822 6.8e-156 ypbG 2.7.1.2 GK ROK family
HIIKPMFB_00823 1.6e-85 C Nitroreductase family
HIIKPMFB_00824 1.3e-108 S Domain of unknown function (DUF4767)
HIIKPMFB_00825 8.1e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HIIKPMFB_00826 6.8e-153 yitS S Uncharacterised protein, DegV family COG1307
HIIKPMFB_00827 1.7e-99 3.6.1.27 I Acid phosphatase homologues
HIIKPMFB_00828 8.7e-192 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HIIKPMFB_00830 4.3e-180 L Belongs to the 'phage' integrase family
HIIKPMFB_00831 2.4e-11
HIIKPMFB_00832 5.8e-83
HIIKPMFB_00834 1.2e-55 ansR 3.4.21.88 K Cro/C1-type HTH DNA-binding domain
HIIKPMFB_00835 4.4e-29 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HIIKPMFB_00836 8.1e-252 yifK E Amino acid permease
HIIKPMFB_00837 6.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIIKPMFB_00838 5.6e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HIIKPMFB_00839 0.0 aha1 P E1-E2 ATPase
HIIKPMFB_00840 5e-159 metQ1 P Belongs to the nlpA lipoprotein family
HIIKPMFB_00841 2.2e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIIKPMFB_00842 7.6e-81 metI P ABC transporter permease
HIIKPMFB_00843 2e-266 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HIIKPMFB_00844 2e-266 frdC 1.3.5.4 C FAD binding domain
HIIKPMFB_00845 8e-293 M domain protein
HIIKPMFB_00846 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HIIKPMFB_00847 1.2e-257 pepC 3.4.22.40 E Peptidase C1-like family
HIIKPMFB_00848 1.2e-274 P Sodium:sulfate symporter transmembrane region
HIIKPMFB_00849 1.1e-155 ydjP I Alpha/beta hydrolase family
HIIKPMFB_00850 8.2e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HIIKPMFB_00851 4.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
HIIKPMFB_00852 1.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HIIKPMFB_00853 9.2e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HIIKPMFB_00854 9.3e-72 yeaL S Protein of unknown function (DUF441)
HIIKPMFB_00855 3.3e-13
HIIKPMFB_00856 3.8e-148 cbiQ P cobalt transport
HIIKPMFB_00857 0.0 ykoD P ABC transporter, ATP-binding protein
HIIKPMFB_00858 7.4e-95 S UPF0397 protein
HIIKPMFB_00859 1.3e-63 S Domain of unknown function DUF1828
HIIKPMFB_00860 2.2e-54
HIIKPMFB_00861 1.2e-177 citR K Putative sugar-binding domain
HIIKPMFB_00862 5.5e-245 yjjP S Putative threonine/serine exporter
HIIKPMFB_00863 1.5e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIIKPMFB_00864 2.1e-174 prmA J Ribosomal protein L11 methyltransferase
HIIKPMFB_00865 4e-49
HIIKPMFB_00866 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIIKPMFB_00867 1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HIIKPMFB_00868 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HIIKPMFB_00869 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HIIKPMFB_00870 2.5e-225 patA 2.6.1.1 E Aminotransferase
HIIKPMFB_00871 2.8e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIIKPMFB_00872 3.5e-154 S reductase
HIIKPMFB_00873 1.6e-151 yxeH S hydrolase
HIIKPMFB_00874 3.1e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIIKPMFB_00875 3.9e-230 yfnA E Amino Acid
HIIKPMFB_00876 2.2e-108 dedA 3.1.3.1 S SNARE associated Golgi protein
HIIKPMFB_00877 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HIIKPMFB_00878 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HIIKPMFB_00879 0.0 I Acyltransferase
HIIKPMFB_00880 2.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HIIKPMFB_00881 7.2e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HIIKPMFB_00882 5.1e-32 yrvD S Lipopolysaccharide assembly protein A domain
HIIKPMFB_00883 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HIIKPMFB_00884 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HIIKPMFB_00886 0.0 dnaE 2.7.7.7 L DNA polymerase
HIIKPMFB_00887 7.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HIIKPMFB_00888 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HIIKPMFB_00889 5e-170 cvfB S S1 domain
HIIKPMFB_00890 1.6e-168 xerD D recombinase XerD
HIIKPMFB_00891 1.7e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIIKPMFB_00892 1.3e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HIIKPMFB_00893 3.2e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HIIKPMFB_00894 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HIIKPMFB_00895 2.2e-117 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIIKPMFB_00896 1.1e-46 M Lysin motif
HIIKPMFB_00897 8.4e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HIIKPMFB_00898 2.3e-202 rpsA 1.17.7.4 J Ribosomal protein S1
HIIKPMFB_00899 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HIIKPMFB_00900 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HIIKPMFB_00901 2.1e-230 S Tetratricopeptide repeat protein
HIIKPMFB_00902 1.3e-162 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIIKPMFB_00903 1.1e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HIIKPMFB_00904 1.2e-107 hlyIII S protein, hemolysin III
HIIKPMFB_00905 2.1e-149 DegV S Uncharacterised protein, DegV family COG1307
HIIKPMFB_00906 2.7e-35 yozE S Belongs to the UPF0346 family
HIIKPMFB_00907 3.5e-283 yjcE P Sodium proton antiporter
HIIKPMFB_00908 1e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HIIKPMFB_00909 1.1e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIIKPMFB_00910 3.6e-157 dprA LU DNA protecting protein DprA
HIIKPMFB_00911 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIIKPMFB_00912 6.1e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HIIKPMFB_00913 7.3e-169 xerC D Phage integrase, N-terminal SAM-like domain
HIIKPMFB_00914 1.1e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HIIKPMFB_00915 1.7e-233 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HIIKPMFB_00916 1.8e-180 lacX 5.1.3.3 G Aldose 1-epimerase
HIIKPMFB_00917 1.5e-65
HIIKPMFB_00918 3.8e-232 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIIKPMFB_00919 3.2e-158 S Alpha/beta hydrolase of unknown function (DUF915)
HIIKPMFB_00920 1.4e-150 xerD L Phage integrase, N-terminal SAM-like domain
HIIKPMFB_00921 3.5e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIIKPMFB_00922 1.1e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIIKPMFB_00923 6.9e-275 pepV 3.5.1.18 E dipeptidase PepV
HIIKPMFB_00924 5.3e-286 E Amino acid permease
HIIKPMFB_00925 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HIIKPMFB_00926 3.2e-247 ynbB 4.4.1.1 P aluminum resistance
HIIKPMFB_00927 3.9e-119 ktrA P domain protein
HIIKPMFB_00928 4e-240 ktrB P Potassium uptake protein
HIIKPMFB_00929 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HIIKPMFB_00930 1.7e-81 C Flavodoxin
HIIKPMFB_00931 0.0 uvrA3 L excinuclease ABC, A subunit
HIIKPMFB_00932 5.9e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HIIKPMFB_00933 1.8e-113 3.6.1.27 I Acid phosphatase homologues
HIIKPMFB_00934 4.5e-67 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIIKPMFB_00935 1.9e-208 pbpX1 V Beta-lactamase
HIIKPMFB_00936 1.5e-155 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HIIKPMFB_00937 3.1e-93 S ECF-type riboflavin transporter, S component
HIIKPMFB_00938 2.1e-216 S Putative peptidoglycan binding domain
HIIKPMFB_00939 6.5e-241
HIIKPMFB_00940 0.0 treB 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIIKPMFB_00941 2.9e-128 treR K UTRA
HIIKPMFB_00942 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HIIKPMFB_00943 2.8e-128 M Glycosyl transferases group 1
HIIKPMFB_00944 3.8e-99 UW LPXTG-motif cell wall anchor domain protein
HIIKPMFB_00945 2.4e-164 M domain protein
HIIKPMFB_00946 2.6e-21 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
HIIKPMFB_00947 0.0 UW LPXTG-motif cell wall anchor domain protein
HIIKPMFB_00948 0.0 UW LPXTG-motif cell wall anchor domain protein
HIIKPMFB_00949 1.2e-28 K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HIIKPMFB_00950 8.8e-164 rocF 3.5.3.1, 3.5.3.11 E Arginase family
HIIKPMFB_00951 2.1e-114 ylbE GM NAD dependent epimerase dehydratase family protein
HIIKPMFB_00952 6.6e-159 K Transcriptional regulator
HIIKPMFB_00953 7.7e-168 S Oxidoreductase, aldo keto reductase family protein
HIIKPMFB_00954 4.3e-166 akr5f 1.1.1.346 S reductase
HIIKPMFB_00955 2.7e-165 yvgN C Aldo keto reductase
HIIKPMFB_00956 4.1e-217 S SLAP domain
HIIKPMFB_00957 4.1e-103 yyaR K Acetyltransferase (GNAT) domain
HIIKPMFB_00960 6.8e-104
HIIKPMFB_00961 6.8e-78 K Transcriptional regulator
HIIKPMFB_00962 1.9e-245 brnQ U Component of the transport system for branched-chain amino acids
HIIKPMFB_00963 3e-164 S reductase
HIIKPMFB_00964 1.3e-170
HIIKPMFB_00965 4.2e-33 K Transcriptional regulator
HIIKPMFB_00966 9.3e-113 papP P ABC transporter, permease protein
HIIKPMFB_00967 2.2e-77 P ABC transporter permease
HIIKPMFB_00968 3.5e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIIKPMFB_00969 7.7e-160 cjaA ET ABC transporter substrate-binding protein
HIIKPMFB_00970 8.3e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HIIKPMFB_00971 8.7e-110 5.4.2.11 G Phosphoglycerate mutase family
HIIKPMFB_00972 3.4e-174 4.1.1.45 S Amidohydrolase
HIIKPMFB_00973 1.1e-29
HIIKPMFB_00974 2.5e-109
HIIKPMFB_00975 4.9e-108
HIIKPMFB_00976 1.3e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
HIIKPMFB_00977 2.3e-215 ynfM EGP Major facilitator Superfamily
HIIKPMFB_00978 1e-153 K Bacterial regulatory helix-turn-helix protein, lysR family
HIIKPMFB_00979 8.2e-119 3.6.1.55 F NUDIX domain
HIIKPMFB_00980 1.3e-76
HIIKPMFB_00981 3.6e-87 FG HIT domain
HIIKPMFB_00982 1.1e-62
HIIKPMFB_00983 3.7e-93 rimL J Acetyltransferase (GNAT) domain
HIIKPMFB_00984 1.1e-101 S Alpha/beta hydrolase family
HIIKPMFB_00985 9.7e-101
HIIKPMFB_00986 1.3e-71
HIIKPMFB_00987 1.5e-146 2.4.2.3 F Phosphorylase superfamily
HIIKPMFB_00988 6.2e-108 5.4.2.11 G Phosphoglycerate mutase family
HIIKPMFB_00989 5.1e-147 2.4.2.3 F Phosphorylase superfamily
HIIKPMFB_00990 1.4e-144 2.4.2.3 F Phosphorylase superfamily
HIIKPMFB_00991 1.4e-112 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HIIKPMFB_00992 7.2e-36
HIIKPMFB_00993 8.3e-53 mleP S Sodium Bile acid symporter family
HIIKPMFB_00994 1.5e-91
HIIKPMFB_00995 1.3e-38
HIIKPMFB_00996 1.8e-167 mleR K LysR family
HIIKPMFB_00997 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HIIKPMFB_00998 1.9e-101 ltrA S Bacterial low temperature requirement A protein (LtrA)
HIIKPMFB_00999 4.4e-244 yrvN L AAA C-terminal domain
HIIKPMFB_01000 2.9e-195 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HIIKPMFB_01001 7.7e-114 S L,D-transpeptidase catalytic domain
HIIKPMFB_01002 4.7e-218 2.1.1.14 E methionine synthase, vitamin-B12 independent
HIIKPMFB_01003 2.3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HIIKPMFB_01004 7.9e-67 L nuclease
HIIKPMFB_01005 3.3e-155 F DNA/RNA non-specific endonuclease
HIIKPMFB_01006 4.3e-115 ywnB S NAD(P)H-binding
HIIKPMFB_01007 1.8e-240 steT E amino acid
HIIKPMFB_01008 4.4e-106 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HIIKPMFB_01009 2.4e-40 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HIIKPMFB_01010 2.2e-148 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HIIKPMFB_01011 0.0 ppc 4.1.1.31 C phosphoenolpyruvate carboxylase activity
HIIKPMFB_01012 0.0
HIIKPMFB_01013 0.0
HIIKPMFB_01014 3.5e-174 yobV1 K WYL domain
HIIKPMFB_01015 3.1e-83 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
HIIKPMFB_01016 2.6e-146 IQ reductase
HIIKPMFB_01017 7.1e-55 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HIIKPMFB_01018 7.2e-115 tas C Aldo/keto reductase family
HIIKPMFB_01019 2.9e-60 C aldo keto reductase
HIIKPMFB_01020 3.6e-146 glcU U ribose uptake protein RbsU
HIIKPMFB_01021 1e-20 C Flavodoxin
HIIKPMFB_01023 2.7e-98 fldA C Flavodoxin
HIIKPMFB_01024 7.7e-100 P esterase
HIIKPMFB_01025 2.4e-261 gor 1.8.1.7 C Glutathione reductase
HIIKPMFB_01026 4.1e-23
HIIKPMFB_01027 4.2e-141 fldA C Flavodoxin
HIIKPMFB_01028 7.8e-97 S LexA-binding, inner membrane-associated putative hydrolase
HIIKPMFB_01029 2.3e-14 C Flavodoxin
HIIKPMFB_01030 2.6e-149 P FAD-binding domain
HIIKPMFB_01031 3.3e-77 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HIIKPMFB_01033 3e-251 yagE E amino acid
HIIKPMFB_01034 1.3e-12 S Alpha beta hydrolase
HIIKPMFB_01035 5e-44 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIIKPMFB_01036 9.2e-17 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIIKPMFB_01037 2.2e-18 magIII L Base excision DNA repair protein, HhH-GPD family
HIIKPMFB_01038 1.9e-168 MA20_14895 S Conserved hypothetical protein 698
HIIKPMFB_01039 7e-101
HIIKPMFB_01040 1.3e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIIKPMFB_01041 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIIKPMFB_01042 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIIKPMFB_01043 7.8e-185 K Transcriptional regulator
HIIKPMFB_01044 2.3e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HIIKPMFB_01045 1.7e-113 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIIKPMFB_01046 1.2e-39 K Helix-turn-helix domain
HIIKPMFB_01047 1.1e-127 yoaK S Protein of unknown function (DUF1275)
HIIKPMFB_01048 8.2e-66 fic D Fic/DOC family
HIIKPMFB_01050 1.5e-286 V ABC-type multidrug transport system, ATPase and permease components
HIIKPMFB_01051 2.3e-287 V ABC-type multidrug transport system, ATPase and permease components
HIIKPMFB_01052 1e-213 EGP Transmembrane secretion effector
HIIKPMFB_01053 3.9e-84 K transcriptional
HIIKPMFB_01054 3.3e-58 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HIIKPMFB_01056 4.3e-200 M Glycosyl hydrolases family 25
HIIKPMFB_01057 2.4e-107 XK27_00160 S Domain of unknown function (DUF5052)
HIIKPMFB_01058 1.5e-91 adk 2.7.4.3 F topology modulation protein
HIIKPMFB_01059 3.1e-59
HIIKPMFB_01060 8.4e-196 xerS L Belongs to the 'phage' integrase family
HIIKPMFB_01061 6.1e-160 degV S EDD domain protein, DegV family
HIIKPMFB_01062 9e-66
HIIKPMFB_01063 0.0 FbpA K Fibronectin-binding protein
HIIKPMFB_01064 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HIIKPMFB_01065 3e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HIIKPMFB_01066 3.2e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIIKPMFB_01067 1.1e-86 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HIIKPMFB_01068 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HIIKPMFB_01069 7.2e-244 cpdA S Calcineurin-like phosphoesterase
HIIKPMFB_01070 1.8e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HIIKPMFB_01071 6.7e-69 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HIIKPMFB_01072 9.4e-106 ypsA S Belongs to the UPF0398 family
HIIKPMFB_01073 7.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HIIKPMFB_01074 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HIIKPMFB_01075 1.5e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HIIKPMFB_01076 5.7e-115 dnaD L DnaD domain protein
HIIKPMFB_01077 2.4e-253 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HIIKPMFB_01078 1.4e-89 ypmB S Protein conserved in bacteria
HIIKPMFB_01079 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HIIKPMFB_01080 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HIIKPMFB_01081 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HIIKPMFB_01082 6.6e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HIIKPMFB_01083 4.1e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HIIKPMFB_01084 8.4e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HIIKPMFB_01085 4.2e-189 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HIIKPMFB_01086 5.2e-145 K SIS domain
HIIKPMFB_01087 1.3e-107 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HIIKPMFB_01088 4.4e-55 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HIIKPMFB_01089 4.6e-216 iscS 2.8.1.7 E Aminotransferase class V
HIIKPMFB_01090 1.1e-267 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HIIKPMFB_01091 3.8e-179
HIIKPMFB_01092 4.1e-141
HIIKPMFB_01093 8.9e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HIIKPMFB_01094 2.2e-27
HIIKPMFB_01095 6.8e-131
HIIKPMFB_01096 4e-145
HIIKPMFB_01097 3.9e-132
HIIKPMFB_01098 1.1e-122 skfE V ATPases associated with a variety of cellular activities
HIIKPMFB_01099 8e-61 yvoA_1 K Transcriptional regulator, GntR family
HIIKPMFB_01100 1.3e-245 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HIIKPMFB_01101 7.7e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HIIKPMFB_01102 1.3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
HIIKPMFB_01103 5.6e-82 mutT 3.6.1.55 F NUDIX domain
HIIKPMFB_01104 1.1e-126 S Peptidase family M23
HIIKPMFB_01105 1.4e-198 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HIIKPMFB_01106 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HIIKPMFB_01107 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HIIKPMFB_01108 2.3e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HIIKPMFB_01109 1.7e-134 recO L Involved in DNA repair and RecF pathway recombination
HIIKPMFB_01110 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIIKPMFB_01111 7.9e-99 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HIIKPMFB_01112 1.3e-176 phoH T phosphate starvation-inducible protein PhoH
HIIKPMFB_01113 6.5e-70 yqeY S YqeY-like protein
HIIKPMFB_01114 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HIIKPMFB_01115 4e-153 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HIIKPMFB_01116 1.3e-95 S Peptidase family M23
HIIKPMFB_01117 2.8e-110 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIIKPMFB_01118 2.2e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIIKPMFB_01119 4.8e-122
HIIKPMFB_01120 4.8e-162 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HIIKPMFB_01121 1.3e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HIIKPMFB_01122 6.4e-287 thrC 4.2.3.1 E Threonine synthase
HIIKPMFB_01123 9.4e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
HIIKPMFB_01124 0.0 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HIIKPMFB_01125 1.1e-18 yjgN S Bacterial protein of unknown function (DUF898)
HIIKPMFB_01126 2.8e-103 lacA 2.3.1.79 S Transferase hexapeptide repeat
HIIKPMFB_01127 0.0
HIIKPMFB_01128 2e-10
HIIKPMFB_01129 4.5e-252 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HIIKPMFB_01130 6.4e-201 brnQ U Component of the transport system for branched-chain amino acids
HIIKPMFB_01131 1.3e-295
HIIKPMFB_01132 1.1e-121 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HIIKPMFB_01133 1.3e-99
HIIKPMFB_01134 2.2e-108 K LysR substrate binding domain
HIIKPMFB_01135 3.7e-15
HIIKPMFB_01136 4.8e-229 S Sterol carrier protein domain
HIIKPMFB_01137 4.8e-99 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HIIKPMFB_01138 1.5e-155 lysR5 K LysR substrate binding domain
HIIKPMFB_01139 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HIIKPMFB_01140 1.8e-87 3.4.21.96 S SLAP domain
HIIKPMFB_01141 3.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIIKPMFB_01142 4.6e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HIIKPMFB_01143 1.6e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HIIKPMFB_01144 1.1e-211 S Bacterial protein of unknown function (DUF871)
HIIKPMFB_01145 4.7e-151 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HIIKPMFB_01147 2.9e-78 K Acetyltransferase (GNAT) domain
HIIKPMFB_01148 3.7e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HIIKPMFB_01149 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HIIKPMFB_01150 4.8e-120 srtA 3.4.22.70 M sortase family
HIIKPMFB_01151 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HIIKPMFB_01152 7.8e-200 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HIIKPMFB_01153 0.0 dnaK O Heat shock 70 kDa protein
HIIKPMFB_01154 1.9e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HIIKPMFB_01155 1.7e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HIIKPMFB_01156 2.5e-283 lsa S ABC transporter
HIIKPMFB_01157 5.2e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HIIKPMFB_01158 1e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HIIKPMFB_01159 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HIIKPMFB_01160 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HIIKPMFB_01161 8.4e-48 rplGA J ribosomal protein
HIIKPMFB_01162 1.4e-47 ylxR K Protein of unknown function (DUF448)
HIIKPMFB_01163 3.3e-198 nusA K Participates in both transcription termination and antitermination
HIIKPMFB_01164 7.2e-83 rimP J Required for maturation of 30S ribosomal subunits
HIIKPMFB_01165 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIIKPMFB_01166 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HIIKPMFB_01167 2.6e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HIIKPMFB_01168 1.7e-145 cdsA 2.7.7.41 I Belongs to the CDS family
HIIKPMFB_01169 9.3e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HIIKPMFB_01170 8.7e-88 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HIIKPMFB_01171 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HIIKPMFB_01172 2.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HIIKPMFB_01173 1.1e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
HIIKPMFB_01174 1.3e-198 yabB 2.1.1.223 L Methyltransferase small domain
HIIKPMFB_01175 6.4e-116 plsC 2.3.1.51 I Acyltransferase
HIIKPMFB_01176 1e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HIIKPMFB_01177 0.0 pepO 3.4.24.71 O Peptidase family M13
HIIKPMFB_01178 3.6e-292 mdlB V ABC transporter
HIIKPMFB_01179 0.0 mdlA V ABC transporter
HIIKPMFB_01180 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
HIIKPMFB_01181 1.1e-37 ynzC S UPF0291 protein
HIIKPMFB_01182 1.5e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIIKPMFB_01183 3.1e-144 E GDSL-like Lipase/Acylhydrolase family
HIIKPMFB_01184 3.7e-122 ung2 3.2.2.27 L Uracil-DNA glycosylase
HIIKPMFB_01185 3.4e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HIIKPMFB_01186 0.0 S Bacterial membrane protein, YfhO
HIIKPMFB_01187 3.7e-70 2.4.1.83 GT2 S GtrA-like protein
HIIKPMFB_01188 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HIIKPMFB_01189 5e-128 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HIIKPMFB_01190 4.7e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HIIKPMFB_01191 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HIIKPMFB_01192 2.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIIKPMFB_01193 1.6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HIIKPMFB_01194 3.2e-259 yfnA E amino acid
HIIKPMFB_01195 2.8e-67
HIIKPMFB_01196 2.5e-288 pipD E Dipeptidase
HIIKPMFB_01197 2.1e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HIIKPMFB_01198 0.0 smc D Required for chromosome condensation and partitioning
HIIKPMFB_01199 3.8e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HIIKPMFB_01200 5.1e-128 K helix_turn_helix, mercury resistance
HIIKPMFB_01201 5e-227 pbuG S permease
HIIKPMFB_01202 5.6e-177 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
HIIKPMFB_01203 0.0 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HIIKPMFB_01204 3.4e-223 pbuG S permease
HIIKPMFB_01205 1.2e-23
HIIKPMFB_01206 3.8e-309 E ABC transporter, substratebinding protein
HIIKPMFB_01207 3.9e-75 atkY K Penicillinase repressor
HIIKPMFB_01208 1.8e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HIIKPMFB_01209 3.7e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HIIKPMFB_01210 0.0 copA 3.6.3.54 P P-type ATPase
HIIKPMFB_01211 2.7e-175 XK27_05540 S DUF218 domain
HIIKPMFB_01212 2.4e-130 WQ51_05710 S Mitochondrial biogenesis AIM24
HIIKPMFB_01213 5.5e-118 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HIIKPMFB_01214 1.5e-18
HIIKPMFB_01215 1.2e-213
HIIKPMFB_01216 1.1e-281 clcA P chloride
HIIKPMFB_01217 5.8e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIIKPMFB_01218 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HIIKPMFB_01219 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HIIKPMFB_01220 3.9e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HIIKPMFB_01221 5.1e-151 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIIKPMFB_01222 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HIIKPMFB_01223 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HIIKPMFB_01224 1.3e-246 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HIIKPMFB_01225 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HIIKPMFB_01226 5.9e-35 yaaA S S4 domain protein YaaA
HIIKPMFB_01227 1.3e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HIIKPMFB_01228 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIIKPMFB_01229 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIIKPMFB_01230 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HIIKPMFB_01231 2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HIIKPMFB_01232 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HIIKPMFB_01233 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HIIKPMFB_01234 2.1e-71 rplI J Binds to the 23S rRNA
HIIKPMFB_01235 5.5e-256 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HIIKPMFB_01236 1.1e-172 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HIIKPMFB_01237 8.3e-176 degV S DegV family
HIIKPMFB_01238 1.6e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HIIKPMFB_01239 1e-16 S CsbD-like
HIIKPMFB_01240 1e-30
HIIKPMFB_01241 1.2e-238 I Protein of unknown function (DUF2974)
HIIKPMFB_01243 6.7e-97 cadD P Cadmium resistance transporter
HIIKPMFB_01244 1.6e-58 cadX K helix_turn_helix, Arsenical Resistance Operon Repressor
HIIKPMFB_01245 5e-184
HIIKPMFB_01246 4.6e-54
HIIKPMFB_01247 1.1e-206 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HIIKPMFB_01248 8.6e-93
HIIKPMFB_01249 4.9e-184 repB EP Plasmid replication protein
HIIKPMFB_01250 1.5e-31
HIIKPMFB_01251 4e-234 L Belongs to the 'phage' integrase family
HIIKPMFB_01252 1.3e-31
HIIKPMFB_01253 6.5e-69 doc S Fic/DOC family
HIIKPMFB_01254 5.3e-20 S Protein of unknown function (DUF3923)
HIIKPMFB_01257 3.9e-161 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HIIKPMFB_01258 2.3e-278 pipD E Dipeptidase
HIIKPMFB_01259 1.3e-230 S LPXTG cell wall anchor motif
HIIKPMFB_01260 3.6e-151 S Putative ABC-transporter type IV
HIIKPMFB_01261 7.7e-100 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HIIKPMFB_01262 4.5e-86 S ECF transporter, substrate-specific component
HIIKPMFB_01263 5.9e-54 S Domain of unknown function (DUF4430)
HIIKPMFB_01264 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HIIKPMFB_01265 7.1e-176 K AI-2E family transporter
HIIKPMFB_01266 3.6e-105 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HIIKPMFB_01267 5.5e-15
HIIKPMFB_01268 7.6e-247 G Major Facilitator
HIIKPMFB_01269 1.7e-52
HIIKPMFB_01270 2.6e-135 XK27_08845 S ABC transporter, ATP-binding protein
HIIKPMFB_01271 2.6e-126 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HIIKPMFB_01272 1.5e-178 ABC-SBP S ABC transporter
HIIKPMFB_01273 4e-138 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HIIKPMFB_01274 0.0 tetP J elongation factor G
HIIKPMFB_01275 1.3e-151 3.1.3.102, 3.1.3.104 S hydrolase
HIIKPMFB_01276 6.5e-30 S endonuclease exonuclease phosphatase family protein
HIIKPMFB_01277 2.7e-134 S endonuclease exonuclease phosphatase family protein
HIIKPMFB_01278 1.4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIIKPMFB_01279 1.8e-153 xth 3.1.11.2 L exodeoxyribonuclease III
HIIKPMFB_01280 1e-273 E amino acid
HIIKPMFB_01281 0.0 L Helicase C-terminal domain protein
HIIKPMFB_01282 2.9e-215 pbpX1 V Beta-lactamase
HIIKPMFB_01283 3.2e-71 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HIIKPMFB_01284 6.6e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HIIKPMFB_01285 0.0 clpE O AAA domain (Cdc48 subfamily)
HIIKPMFB_01286 5.1e-170 S Alpha/beta hydrolase of unknown function (DUF915)
HIIKPMFB_01287 1.4e-229 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIIKPMFB_01288 5e-125 XK27_06785 V ABC transporter, ATP-binding protein
HIIKPMFB_01289 0.0 XK27_06780 V ABC transporter permease
HIIKPMFB_01290 9.6e-36
HIIKPMFB_01291 7.4e-289 ytgP S Polysaccharide biosynthesis protein
HIIKPMFB_01292 4.3e-167 lysA2 M Glycosyl hydrolases family 25
HIIKPMFB_01293 4.4e-126 S Protein of unknown function (DUF975)
HIIKPMFB_01294 2.7e-61
HIIKPMFB_01295 2e-177 pbpX2 V Beta-lactamase
HIIKPMFB_01296 3.9e-248 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HIIKPMFB_01297 7.4e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIIKPMFB_01298 2.6e-241 dltB M MBOAT, membrane-bound O-acyltransferase family
HIIKPMFB_01299 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIIKPMFB_01300 7.6e-18 S D-Ala-teichoic acid biosynthesis protein
HIIKPMFB_01301 3.6e-40
HIIKPMFB_01302 9.1e-217 ywhK S Membrane
HIIKPMFB_01303 2.1e-82 ykuL S (CBS) domain
HIIKPMFB_01304 0.0 cadA P P-type ATPase
HIIKPMFB_01305 5e-194 napA P Sodium/hydrogen exchanger family
HIIKPMFB_01306 3.5e-72 S Putative adhesin
HIIKPMFB_01307 4.3e-286 V ABC transporter transmembrane region
HIIKPMFB_01308 2.8e-154 mutR K Helix-turn-helix XRE-family like proteins
HIIKPMFB_01309 3.2e-97 M CHAP domain
HIIKPMFB_01310 1.5e-68 K Helix-turn-helix XRE-family like proteins
HIIKPMFB_01311 2.7e-120 S CAAX protease self-immunity
HIIKPMFB_01312 1.6e-194 S DUF218 domain
HIIKPMFB_01313 0.0 macB_3 V ABC transporter, ATP-binding protein
HIIKPMFB_01314 1.6e-103 S ECF transporter, substrate-specific component
HIIKPMFB_01315 5.6e-186 tcsA S ABC transporter substrate-binding protein PnrA-like
HIIKPMFB_01316 5.6e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
HIIKPMFB_01317 1.7e-287 xylG 3.6.3.17 S ABC transporter
HIIKPMFB_01318 5.1e-207 yufP S Belongs to the binding-protein-dependent transport system permease family
HIIKPMFB_01319 2.4e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
HIIKPMFB_01320 1.7e-159 yeaE S Aldo/keto reductase family
HIIKPMFB_01321 2.5e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIIKPMFB_01322 4.7e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HIIKPMFB_01323 1.4e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HIIKPMFB_01324 8.5e-145 cof S haloacid dehalogenase-like hydrolase
HIIKPMFB_01325 1.1e-231 pbuG S permease
HIIKPMFB_01326 6e-188 purR13 K Bacterial regulatory proteins, lacI family
HIIKPMFB_01327 1.2e-154 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
HIIKPMFB_01328 1.3e-176 tktA 2.2.1.1 G Transketolase, pyrimidine binding domain
HIIKPMFB_01329 1.6e-258 glpK_1 2.7.1.30 G FGGY family of carbohydrate kinases, C-terminal domain
HIIKPMFB_01330 7.4e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIIKPMFB_01331 1.9e-248 lmrB EGP Major facilitator Superfamily
HIIKPMFB_01334 4.1e-152
HIIKPMFB_01335 4e-167
HIIKPMFB_01336 1.8e-116 ybbL S ABC transporter, ATP-binding protein
HIIKPMFB_01337 5.5e-133 ybbM S Uncharacterised protein family (UPF0014)
HIIKPMFB_01338 8.9e-264 glnA 6.3.1.2 E glutamine synthetase
HIIKPMFB_01339 1.9e-239 ynbB 4.4.1.1 P aluminum resistance
HIIKPMFB_01340 2.1e-171 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HIIKPMFB_01341 3.3e-65 yqhL P Rhodanese-like protein
HIIKPMFB_01342 1.6e-32 yqgQ S Bacterial protein of unknown function (DUF910)
HIIKPMFB_01343 1.2e-118 gluP 3.4.21.105 S Rhomboid family
HIIKPMFB_01344 1.1e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HIIKPMFB_01345 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HIIKPMFB_01346 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HIIKPMFB_01347 0.0 S membrane
HIIKPMFB_01348 2.3e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HIIKPMFB_01349 0.0 O Belongs to the peptidase S8 family
HIIKPMFB_01350 1.7e-35 ltrA S Bacterial low temperature requirement A protein (LtrA)
HIIKPMFB_01351 1.1e-12 ltrA S Bacterial low temperature requirement A protein (LtrA)
HIIKPMFB_01352 3.6e-254 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HIIKPMFB_01353 6.7e-170 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HIIKPMFB_01354 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIIKPMFB_01355 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIIKPMFB_01356 1.2e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HIIKPMFB_01357 4.7e-63 yodB K Transcriptional regulator, HxlR family
HIIKPMFB_01358 1.9e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIIKPMFB_01359 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HIIKPMFB_01360 4.3e-159 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIIKPMFB_01361 1.9e-249 arlS 2.7.13.3 T Histidine kinase
HIIKPMFB_01362 2.5e-127 K response regulator
HIIKPMFB_01363 2.4e-98 yceD S Uncharacterized ACR, COG1399
HIIKPMFB_01364 2.7e-216 ylbM S Belongs to the UPF0348 family
HIIKPMFB_01365 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HIIKPMFB_01366 1.4e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HIIKPMFB_01367 5.2e-124 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HIIKPMFB_01368 1e-212 yqeH S Ribosome biogenesis GTPase YqeH
HIIKPMFB_01369 1.6e-93 yqeG S HAD phosphatase, family IIIA
HIIKPMFB_01370 1.9e-198 tnpB L Putative transposase DNA-binding domain
HIIKPMFB_01371 3.5e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HIIKPMFB_01372 1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HIIKPMFB_01373 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HIIKPMFB_01374 3.7e-73 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HIIKPMFB_01375 3.2e-92
HIIKPMFB_01376 5.7e-71 S Protein of unknown function (DUF3021)
HIIKPMFB_01377 5.6e-74 K LytTr DNA-binding domain
HIIKPMFB_01378 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIIKPMFB_01379 6.9e-167 dnaI L Primosomal protein DnaI
HIIKPMFB_01380 1.7e-251 dnaB L Replication initiation and membrane attachment
HIIKPMFB_01381 2.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HIIKPMFB_01382 6.9e-107 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIIKPMFB_01383 4.8e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HIIKPMFB_01384 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIIKPMFB_01385 5.3e-250 purD 6.3.4.13 F Belongs to the GARS family
HIIKPMFB_01386 5e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HIIKPMFB_01387 2.7e-111 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HIIKPMFB_01388 2e-199 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HIIKPMFB_01389 1.5e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HIIKPMFB_01390 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIIKPMFB_01391 6.1e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIIKPMFB_01392 7.6e-39 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIIKPMFB_01393 2.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HIIKPMFB_01394 3.6e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HIIKPMFB_01395 9.6e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HIIKPMFB_01396 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HIIKPMFB_01397 1.1e-124 darA C Flavodoxin
HIIKPMFB_01398 9.7e-142 qmcA O prohibitin homologues
HIIKPMFB_01399 1.1e-50 L RelB antitoxin
HIIKPMFB_01400 2.4e-194 S Bacteriocin helveticin-J
HIIKPMFB_01401 7.9e-293 M Peptidase family M1 domain
HIIKPMFB_01402 3.2e-178 S SLAP domain
HIIKPMFB_01403 1.9e-112 L Putative transposase DNA-binding domain
HIIKPMFB_01404 1.2e-97 L Putative transposase DNA-binding domain
HIIKPMFB_01405 2.9e-238 mepA V MATE efflux family protein
HIIKPMFB_01406 6.6e-167 rocF 3.5.3.1, 3.5.3.11 E Arginase family
HIIKPMFB_01407 1.8e-92 S Membrane
HIIKPMFB_01408 3.1e-294 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIIKPMFB_01409 5.5e-295 G phosphotransferase system
HIIKPMFB_01410 1.2e-29 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HIIKPMFB_01411 1.7e-148 ybbH K Helix-turn-helix domain, rpiR family
HIIKPMFB_01412 0.0
HIIKPMFB_01413 4.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HIIKPMFB_01414 7.4e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIIKPMFB_01415 1.1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HIIKPMFB_01416 1.5e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HIIKPMFB_01417 7.4e-201 ecsB U ABC transporter
HIIKPMFB_01418 2e-135 ecsA V ABC transporter, ATP-binding protein
HIIKPMFB_01419 2.8e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
HIIKPMFB_01420 1.4e-56
HIIKPMFB_01421 1.1e-148 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HIIKPMFB_01422 8.4e-187 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HIIKPMFB_01423 0.0 L AAA domain
HIIKPMFB_01424 2.4e-231 yhaO L Ser Thr phosphatase family protein
HIIKPMFB_01425 6.8e-54 yheA S Belongs to the UPF0342 family
HIIKPMFB_01426 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HIIKPMFB_01427 2.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIIKPMFB_01428 1.6e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HIIKPMFB_01429 6.8e-119
HIIKPMFB_01430 4.1e-192 5.3.3.2 C FMN-dependent dehydrogenase
HIIKPMFB_01431 2.7e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HIIKPMFB_01432 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HIIKPMFB_01433 6.9e-127 M ErfK YbiS YcfS YnhG
HIIKPMFB_01434 8.1e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HIIKPMFB_01435 1.7e-243 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HIIKPMFB_01437 6.4e-54 pspC KT PspC domain
HIIKPMFB_01438 5.5e-197 V Beta-lactamase
HIIKPMFB_01439 3e-54 yvlA
HIIKPMFB_01440 7e-258 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
HIIKPMFB_01441 9.1e-40 S Enterocin A Immunity
HIIKPMFB_01442 0.0 S domain, Protein
HIIKPMFB_01443 3.8e-80 yphH S Cupin domain
HIIKPMFB_01444 0.0 sprD D Domain of Unknown Function (DUF1542)
HIIKPMFB_01445 2.8e-17 K transcriptional regulator
HIIKPMFB_01446 5.5e-71 K transcriptional regulator
HIIKPMFB_01447 4.8e-16
HIIKPMFB_01448 2.2e-296 ytgP S Polysaccharide biosynthesis protein
HIIKPMFB_01449 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIIKPMFB_01450 3.9e-119 3.6.1.27 I Acid phosphatase homologues
HIIKPMFB_01451 4.4e-91 ndh 1.6.99.3 C NADH dehydrogenase
HIIKPMFB_01452 2.3e-116 ndh 1.6.99.3 C NADH dehydrogenase
HIIKPMFB_01453 1.5e-30 cydA 1.10.3.14 C ubiquinol oxidase
HIIKPMFB_01454 2.9e-260 qacA EGP Major facilitator Superfamily
HIIKPMFB_01455 2.4e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HIIKPMFB_01459 1.8e-253 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HIIKPMFB_01460 1.4e-101 J Acetyltransferase (GNAT) domain
HIIKPMFB_01461 2.7e-111 yjbF S SNARE associated Golgi protein
HIIKPMFB_01462 3.2e-152 I alpha/beta hydrolase fold
HIIKPMFB_01463 4.5e-160 hipB K Helix-turn-helix
HIIKPMFB_01464 2.1e-93 F Nucleoside 2-deoxyribosyltransferase
HIIKPMFB_01465 2.1e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HIIKPMFB_01466 0.0 fhaB M Rib/alpha-like repeat
HIIKPMFB_01467 0.0 fhaB M Rib/alpha-like repeat
HIIKPMFB_01468 2.4e-163
HIIKPMFB_01469 0.0 ydgH S MMPL family
HIIKPMFB_01470 2.3e-96 yobS K Bacterial regulatory proteins, tetR family
HIIKPMFB_01471 1.5e-148 3.5.2.6 V Beta-lactamase enzyme family
HIIKPMFB_01472 4e-154 corA P CorA-like Mg2+ transporter protein
HIIKPMFB_01473 1.3e-235 G Bacterial extracellular solute-binding protein
HIIKPMFB_01474 3.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HIIKPMFB_01475 9.4e-147 gtsC P Binding-protein-dependent transport system inner membrane component
HIIKPMFB_01476 2.2e-154 gtsB P ABC-type sugar transport systems, permease components
HIIKPMFB_01477 7.1e-203 malK P ATPases associated with a variety of cellular activities
HIIKPMFB_01478 2.8e-284 pipD E Dipeptidase
HIIKPMFB_01479 1.6e-157 endA F DNA RNA non-specific endonuclease
HIIKPMFB_01480 1.9e-183 dnaQ 2.7.7.7 L EXOIII
HIIKPMFB_01481 1.4e-155 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HIIKPMFB_01482 1.5e-115 yviA S Protein of unknown function (DUF421)
HIIKPMFB_01483 3.4e-74 S Protein of unknown function (DUF3290)
HIIKPMFB_01484 0.0 sdrF M domain protein
HIIKPMFB_01485 4.5e-140 pnuC H nicotinamide mononucleotide transporter
HIIKPMFB_01486 6.2e-264
HIIKPMFB_01487 3.5e-48
HIIKPMFB_01488 1.5e-143 S PAS domain
HIIKPMFB_01489 4.8e-296 V ABC transporter transmembrane region
HIIKPMFB_01490 1.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HIIKPMFB_01491 1.8e-127 T Transcriptional regulatory protein, C terminal
HIIKPMFB_01492 5.4e-245 T GHKL domain
HIIKPMFB_01493 2.1e-86 S Peptidase propeptide and YPEB domain
HIIKPMFB_01494 2.3e-97 S Peptidase propeptide and YPEB domain
HIIKPMFB_01495 2.8e-76 yybA 2.3.1.57 K Transcriptional regulator
HIIKPMFB_01496 6.8e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HIIKPMFB_01497 0.0 E ABC transporter, substratebinding protein
HIIKPMFB_01498 1.1e-54 ypaA S Protein of unknown function (DUF1304)
HIIKPMFB_01499 4.6e-100 S Peptidase propeptide and YPEB domain
HIIKPMFB_01500 9.9e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIIKPMFB_01501 3.5e-171 coaA 2.7.1.33 F Pantothenic acid kinase
HIIKPMFB_01502 6.7e-104 E GDSL-like Lipase/Acylhydrolase
HIIKPMFB_01503 9.9e-82 yjcF S Acetyltransferase (GNAT) domain
HIIKPMFB_01504 2.8e-151 aatB ET ABC transporter substrate-binding protein
HIIKPMFB_01505 9e-110 glnQ 3.6.3.21 E ABC transporter
HIIKPMFB_01506 3e-108 glnP P ABC transporter permease
HIIKPMFB_01507 1.1e-22 helD 3.6.4.12 L DNA helicase
HIIKPMFB_01508 0.0 helD 3.6.4.12 L DNA helicase
HIIKPMFB_01509 9.9e-126 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HIIKPMFB_01510 8.5e-127 pgm3 5.4.2.11 G Phosphoglycerate mutase family
HIIKPMFB_01511 0.0 V FtsX-like permease family
HIIKPMFB_01512 1.7e-134 cysA V ABC transporter, ATP-binding protein
HIIKPMFB_01513 1.6e-241 S response to antibiotic
HIIKPMFB_01514 1.1e-127
HIIKPMFB_01515 0.0 3.6.3.8 P P-type ATPase
HIIKPMFB_01516 2.1e-64 2.7.1.191 G PTS system fructose IIA component
HIIKPMFB_01517 2.1e-48
HIIKPMFB_01518 1.9e-15
HIIKPMFB_01519 4.2e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
HIIKPMFB_01520 1.5e-138 glvR K Helix-turn-helix domain, rpiR family
HIIKPMFB_01521 4.1e-269 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HIIKPMFB_01522 4.3e-155
HIIKPMFB_01523 3.4e-91
HIIKPMFB_01524 4.2e-106 3.2.2.20 K acetyltransferase
HIIKPMFB_01527 4.4e-311 asdA 4.1.1.12 E Aminotransferase
HIIKPMFB_01528 3.2e-303 aspT P Predicted Permease Membrane Region
HIIKPMFB_01529 4.2e-189 S Domain of unknown function (DUF4767)
HIIKPMFB_01530 2.5e-184 S Membrane
HIIKPMFB_01531 6.4e-150 xth 3.1.11.2 L exodeoxyribonuclease III
HIIKPMFB_01532 7.9e-188 K helix_turn_helix, arabinose operon control protein
HIIKPMFB_01533 7.8e-188 K helix_turn_helix, arabinose operon control protein
HIIKPMFB_01534 4.7e-149 K Helix-turn-helix domain, rpiR family
HIIKPMFB_01535 7.7e-202 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HIIKPMFB_01536 3.7e-157 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HIIKPMFB_01537 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIIKPMFB_01538 1.6e-298 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIIKPMFB_01539 0.0 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIIKPMFB_01540 2.5e-158 K CAT RNA binding domain
HIIKPMFB_01541 0.0 M Leucine-rich repeat (LRR) protein
HIIKPMFB_01543 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HIIKPMFB_01544 1.2e-91
HIIKPMFB_01545 1.6e-182
HIIKPMFB_01546 9.7e-271 S Uncharacterised protein conserved in bacteria (DUF2326)
HIIKPMFB_01547 7.6e-10
HIIKPMFB_01553 2.2e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HIIKPMFB_01554 4.1e-217 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HIIKPMFB_01555 2.3e-63 L PFAM Integrase catalytic region
HIIKPMFB_01556 1e-136 L transposase activity
HIIKPMFB_01557 5.2e-234 L COG3547 Transposase and inactivated derivatives
HIIKPMFB_01558 4.6e-266 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HIIKPMFB_01559 4.8e-96 glf 5.4.99.9 M UDP-galactopyranose mutase
HIIKPMFB_01560 9.1e-71 glf 5.4.99.9 M Flavin containing amine oxidoreductase
HIIKPMFB_01561 4.2e-218 S Psort location CytoplasmicMembrane, score 9.99
HIIKPMFB_01562 1.2e-188 M Glycosyltransferase like family 2
HIIKPMFB_01563 1.4e-121 M transferase activity, transferring glycosyl groups
HIIKPMFB_01564 4.9e-24 M transferase activity, transferring glycosyl groups
HIIKPMFB_01565 2.5e-166 glfT1 1.1.1.133 S Glycosyltransferase like family 2
HIIKPMFB_01566 1.6e-148 cps1D M Domain of unknown function (DUF4422)
HIIKPMFB_01567 1.1e-123 rfbP M Bacterial sugar transferase
HIIKPMFB_01568 3.6e-148 ywqE 3.1.3.48 GM PHP domain protein
HIIKPMFB_01569 1.5e-125 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HIIKPMFB_01570 1.6e-141 epsB M biosynthesis protein
HIIKPMFB_01571 4e-174 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HIIKPMFB_01572 4e-205 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIIKPMFB_01573 3.2e-189 S Cysteine-rich secretory protein family
HIIKPMFB_01574 0.0 2.7.13.3 M Mycoplasma protein of unknown function, DUF285
HIIKPMFB_01575 3.7e-128 M NlpC/P60 family
HIIKPMFB_01576 2.3e-126 M NlpC P60 family protein
HIIKPMFB_01577 7.6e-84 M NlpC/P60 family
HIIKPMFB_01578 1.8e-85 gmk2 2.7.4.8 F Guanylate kinase homologues.
HIIKPMFB_01579 5.6e-33
HIIKPMFB_01580 1e-279 S O-antigen ligase like membrane protein
HIIKPMFB_01581 8.1e-111
HIIKPMFB_01582 3.8e-78 nrdI F NrdI Flavodoxin like
HIIKPMFB_01583 1.7e-181 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIIKPMFB_01584 7.8e-78
HIIKPMFB_01585 7.7e-137 yvpB S Peptidase_C39 like family
HIIKPMFB_01586 5.2e-53 yitW S Iron-sulfur cluster assembly protein
HIIKPMFB_01587 8.8e-47 sufB O assembly protein SufB
HIIKPMFB_01588 4.6e-35 sufC O FeS assembly ATPase SufC
HIIKPMFB_01589 7.8e-85 S Threonine/Serine exporter, ThrE
HIIKPMFB_01590 4.4e-138 thrE S Putative threonine/serine exporter
HIIKPMFB_01591 2.1e-293 S ABC transporter
HIIKPMFB_01592 3.6e-61
HIIKPMFB_01593 1.3e-45 rimL J Acetyltransferase (GNAT) domain
HIIKPMFB_01594 1.5e-223 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HIIKPMFB_01595 0.0 pepF E oligoendopeptidase F
HIIKPMFB_01596 6.7e-44 P transmembrane transport
HIIKPMFB_01597 7e-265 lctP C L-lactate permease
HIIKPMFB_01598 1.4e-62 pdxH S Pyridoxamine 5'-phosphate oxidase
HIIKPMFB_01599 7.9e-135 znuB U ABC 3 transport family
HIIKPMFB_01600 1e-116 fhuC P ABC transporter
HIIKPMFB_01601 6.4e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
HIIKPMFB_01602 2.5e-43 K helix_turn_helix, Arsenical Resistance Operon Repressor
HIIKPMFB_01603 5.1e-75 K LytTr DNA-binding domain
HIIKPMFB_01604 5.5e-47 S Protein of unknown function (DUF3021)
HIIKPMFB_01605 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HIIKPMFB_01606 3.3e-169 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HIIKPMFB_01607 2.3e-136 fruR K DeoR C terminal sensor domain
HIIKPMFB_01608 7.4e-197 fic S Fic/DOC family
HIIKPMFB_01609 3.9e-218 natB CP ABC-2 family transporter protein
HIIKPMFB_01610 2.6e-166 natA S ABC transporter, ATP-binding protein
HIIKPMFB_01611 6.2e-08
HIIKPMFB_01612 4e-69
HIIKPMFB_01613 2.1e-25
HIIKPMFB_01614 8.2e-31 yozG K Transcriptional regulator
HIIKPMFB_01615 9e-90
HIIKPMFB_01616 8.8e-21
HIIKPMFB_01621 8.1e-209 blpT
HIIKPMFB_01622 3.4e-106 M Transport protein ComB
HIIKPMFB_01623 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HIIKPMFB_01624 4.2e-07
HIIKPMFB_01626 1.6e-146 K LytTr DNA-binding domain
HIIKPMFB_01627 2.8e-233 2.7.13.3 T GHKL domain
HIIKPMFB_01631 7e-110
HIIKPMFB_01633 5.1e-109 S CAAX protease self-immunity
HIIKPMFB_01634 1.2e-216 S CAAX protease self-immunity
HIIKPMFB_01635 1.4e-37 S Enterocin A Immunity
HIIKPMFB_01636 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HIIKPMFB_01637 1.1e-26
HIIKPMFB_01638 1.5e-33
HIIKPMFB_01639 4e-53 S Enterocin A Immunity
HIIKPMFB_01640 9.4e-49 S Enterocin A Immunity
HIIKPMFB_01641 7.2e-146 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HIIKPMFB_01642 2.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIIKPMFB_01643 5.8e-195 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HIIKPMFB_01644 2.5e-121 K response regulator
HIIKPMFB_01645 0.0 V ABC transporter
HIIKPMFB_01646 1.3e-304 V ABC transporter, ATP-binding protein
HIIKPMFB_01647 2e-138 XK27_01040 S Protein of unknown function (DUF1129)
HIIKPMFB_01648 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HIIKPMFB_01649 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
HIIKPMFB_01650 3.4e-155 spo0J K Belongs to the ParB family
HIIKPMFB_01651 1.3e-137 soj D Sporulation initiation inhibitor
HIIKPMFB_01652 7.2e-147 noc K Belongs to the ParB family
HIIKPMFB_01653 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HIIKPMFB_01654 7.9e-54 cvpA S Colicin V production protein
HIIKPMFB_01655 3.5e-182 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HIIKPMFB_01656 2.5e-149 3.1.3.48 T Tyrosine phosphatase family
HIIKPMFB_01657 3.1e-98 azr 1.5.1.36 S NADPH-dependent FMN reductase
HIIKPMFB_01658 7.6e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HIIKPMFB_01659 1.3e-111 K WHG domain
HIIKPMFB_01660 6.9e-19
HIIKPMFB_01661 1.1e-277 pipD E Dipeptidase
HIIKPMFB_01662 9.8e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HIIKPMFB_01663 1.3e-180 hrtB V ABC transporter permease
HIIKPMFB_01664 4.8e-96 ygfC K Bacterial regulatory proteins, tetR family
HIIKPMFB_01665 2.4e-112 3.1.3.73 G phosphoglycerate mutase
HIIKPMFB_01666 2e-140 aroD S Alpha/beta hydrolase family
HIIKPMFB_01667 2e-143 S Belongs to the UPF0246 family
HIIKPMFB_01668 3.8e-119
HIIKPMFB_01669 1.1e-157 2.7.7.12 C Domain of unknown function (DUF4931)
HIIKPMFB_01670 9.3e-220 S Putative peptidoglycan binding domain
HIIKPMFB_01671 2.6e-26
HIIKPMFB_01672 1.3e-252 dtpT U amino acid peptide transporter
HIIKPMFB_01673 0.0 pepN 3.4.11.2 E aminopeptidase
HIIKPMFB_01674 4.5e-61 lysM M LysM domain
HIIKPMFB_01675 4.7e-177
HIIKPMFB_01676 2.8e-102 mdtG EGP Major Facilitator Superfamily
HIIKPMFB_01677 2.9e-114 mdtG EGP Major facilitator Superfamily
HIIKPMFB_01679 6e-213 I transferase activity, transferring acyl groups other than amino-acyl groups
HIIKPMFB_01680 1.2e-91 ymdB S Macro domain protein
HIIKPMFB_01681 0.0 nisT V ABC transporter
HIIKPMFB_01682 3.7e-07
HIIKPMFB_01684 1.6e-146 K Helix-turn-helix XRE-family like proteins
HIIKPMFB_01685 6.7e-84
HIIKPMFB_01686 1.4e-148 malG P ABC transporter permease
HIIKPMFB_01687 7.9e-252 malF P Binding-protein-dependent transport system inner membrane component
HIIKPMFB_01688 5.9e-214 malE G Bacterial extracellular solute-binding protein
HIIKPMFB_01689 1.6e-210 msmX P Belongs to the ABC transporter superfamily
HIIKPMFB_01690 2e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HIIKPMFB_01691 3.7e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIIKPMFB_01692 1.1e-34 S Protein of unknown function (DUF2508)
HIIKPMFB_01693 2.3e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIIKPMFB_01694 5.8e-52 yaaQ S Cyclic-di-AMP receptor
HIIKPMFB_01695 2.6e-155 holB 2.7.7.7 L DNA polymerase III
HIIKPMFB_01696 3e-60 yabA L Involved in initiation control of chromosome replication
HIIKPMFB_01697 6.7e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIIKPMFB_01698 9.6e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
HIIKPMFB_01699 5.2e-87 S ECF transporter, substrate-specific component
HIIKPMFB_01700 1.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HIIKPMFB_01701 3.3e-106 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HIIKPMFB_01702 1.1e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HIIKPMFB_01703 1.3e-131 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HIIKPMFB_01704 2.1e-182 S Oxidoreductase family, NAD-binding Rossmann fold
HIIKPMFB_01705 4.9e-128 yegW K UTRA
HIIKPMFB_01706 6.5e-234 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HIIKPMFB_01707 4.3e-266 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HIIKPMFB_01708 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HIIKPMFB_01709 0.0 uup S ABC transporter, ATP-binding protein
HIIKPMFB_01710 1.3e-111 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HIIKPMFB_01711 1e-184 scrR K helix_turn _helix lactose operon repressor
HIIKPMFB_01712 5.6e-296 scrB 3.2.1.26 GH32 G invertase
HIIKPMFB_01713 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HIIKPMFB_01714 5.8e-75
HIIKPMFB_01715 1.1e-77 XK27_02470 K LytTr DNA-binding domain
HIIKPMFB_01716 6.9e-128 liaI S membrane
HIIKPMFB_01717 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HIIKPMFB_01718 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HIIKPMFB_01719 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HIIKPMFB_01720 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HIIKPMFB_01721 2.7e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HIIKPMFB_01722 4.6e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HIIKPMFB_01723 1.1e-47 yajC U Preprotein translocase
HIIKPMFB_01724 5.3e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HIIKPMFB_01725 2.2e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIIKPMFB_01726 6.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HIIKPMFB_01727 3.3e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HIIKPMFB_01728 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIIKPMFB_01729 2e-42 yrzL S Belongs to the UPF0297 family
HIIKPMFB_01730 2.7e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HIIKPMFB_01731 2.8e-51 yrzB S Belongs to the UPF0473 family
HIIKPMFB_01732 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HIIKPMFB_01733 6e-54 trxA O Belongs to the thioredoxin family
HIIKPMFB_01734 4e-36 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HIIKPMFB_01735 2.3e-69 yslB S Protein of unknown function (DUF2507)
HIIKPMFB_01736 3.8e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HIIKPMFB_01737 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HIIKPMFB_01738 8.2e-130 ykuT M mechanosensitive ion channel
HIIKPMFB_01739 3.6e-09 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HIIKPMFB_01740 2.1e-45
HIIKPMFB_01741 7.5e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HIIKPMFB_01742 2.9e-182 ccpA K catabolite control protein A
HIIKPMFB_01743 3.9e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HIIKPMFB_01744 1.9e-55
HIIKPMFB_01745 5.2e-275 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HIIKPMFB_01746 1.3e-81 yutD S Protein of unknown function (DUF1027)
HIIKPMFB_01747 7.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HIIKPMFB_01748 1.1e-107 S Protein of unknown function (DUF1461)
HIIKPMFB_01749 2.3e-116 dedA S SNARE-like domain protein
HIIKPMFB_01750 1.1e-150 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HIIKPMFB_01751 2.2e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HIIKPMFB_01752 1.1e-248 yhdP S Transporter associated domain
HIIKPMFB_01753 1.6e-120 C nitroreductase
HIIKPMFB_01754 1.9e-40
HIIKPMFB_01755 1.1e-86 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HIIKPMFB_01756 2.9e-82
HIIKPMFB_01757 7.6e-149 glvR K Helix-turn-helix domain, rpiR family
HIIKPMFB_01758 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HIIKPMFB_01759 2.3e-153 S hydrolase
HIIKPMFB_01760 3.4e-222 S CAAX protease self-immunity
HIIKPMFB_01761 5e-145 K LytTr DNA-binding domain
HIIKPMFB_01762 3.8e-224 2.7.13.3 T GHKL domain
HIIKPMFB_01763 5.3e-161 rssA S Phospholipase, patatin family
HIIKPMFB_01764 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HIIKPMFB_01765 1.3e-137 glcR K DeoR C terminal sensor domain
HIIKPMFB_01766 1.9e-59 S Enterocin A Immunity
HIIKPMFB_01767 0.0 lmrA 3.6.3.44 V ABC transporter
HIIKPMFB_01768 5.3e-72 K helix_turn_helix multiple antibiotic resistance protein
HIIKPMFB_01769 1.8e-153 S hydrolase
HIIKPMFB_01770 2.9e-285 V ABC transporter transmembrane region
HIIKPMFB_01771 1.2e-112
HIIKPMFB_01772 2.6e-22
HIIKPMFB_01773 3.3e-135 gntR K UbiC transcription regulator-associated domain protein
HIIKPMFB_01774 6.3e-176 rihB 3.2.2.1 F Nucleoside
HIIKPMFB_01775 0.0 kup P Transport of potassium into the cell
HIIKPMFB_01776 2e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HIIKPMFB_01777 5.9e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIIKPMFB_01778 4.1e-163 2.7.7.12 C Domain of unknown function (DUF4931)
HIIKPMFB_01779 4.8e-238 G Bacterial extracellular solute-binding protein
HIIKPMFB_01780 1.2e-63
HIIKPMFB_01781 1.5e-174 S Protein of unknown function (DUF2974)
HIIKPMFB_01782 1.9e-110 glnP P ABC transporter permease
HIIKPMFB_01783 6.1e-93 gluC P ABC transporter permease
HIIKPMFB_01784 1.3e-148 glnH ET ABC transporter substrate-binding protein
HIIKPMFB_01785 7.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIIKPMFB_01786 7.2e-115 udk 2.7.1.48 F Zeta toxin
HIIKPMFB_01787 2.9e-102 S ABC-type cobalt transport system, permease component
HIIKPMFB_01788 0.0 V ABC transporter transmembrane region
HIIKPMFB_01789 1.1e-306 XK27_09600 V ABC transporter, ATP-binding protein
HIIKPMFB_01790 2.3e-78 K Transcriptional regulator, MarR family
HIIKPMFB_01791 9e-150 glnH ET ABC transporter
HIIKPMFB_01792 9.8e-146
HIIKPMFB_01793 0.0 ybiT S ABC transporter, ATP-binding protein
HIIKPMFB_01794 2.1e-210 pepA E M42 glutamyl aminopeptidase
HIIKPMFB_01795 1.8e-165 mleP3 S Membrane transport protein
HIIKPMFB_01796 4e-215 mdtG EGP Major facilitator Superfamily
HIIKPMFB_01797 1.6e-253 emrY EGP Major facilitator Superfamily
HIIKPMFB_01798 2.4e-50 3.1.3.102, 3.1.3.104 Q phosphatase activity
HIIKPMFB_01799 1.5e-86 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HIIKPMFB_01800 9.5e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIIKPMFB_01801 2.1e-241 pyrP F Permease
HIIKPMFB_01802 5.1e-128 cydD V cysteine transport
HIIKPMFB_01803 3.6e-109 V ABC-type multidrug transport system, ATPase and permease components
HIIKPMFB_01804 8e-162 S reductase
HIIKPMFB_01805 8.4e-78 2.3.1.128 K acetyltransferase
HIIKPMFB_01806 0.0 4.2.1.53 S Myosin-crossreactive antigen
HIIKPMFB_01807 5e-90 yxdD K Bacterial regulatory proteins, tetR family
HIIKPMFB_01808 6.8e-136 S CAAX protease self-immunity
HIIKPMFB_01809 3.9e-244 emrY EGP Major facilitator Superfamily
HIIKPMFB_01814 6.6e-95 MA20_25245 K Acetyltransferase (GNAT) domain
HIIKPMFB_01815 1.4e-178 L Recombinase zinc beta ribbon domain
HIIKPMFB_01816 7.8e-94 L Resolvase, N terminal domain
HIIKPMFB_01817 9e-192 L Recombinase
HIIKPMFB_01818 6.5e-57 5.1.1.13 M Asp/Glu/Hydantoin racemase
HIIKPMFB_01819 1.2e-48 5.1.1.13 M Asp/Glu/Hydantoin racemase
HIIKPMFB_01820 2.8e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
HIIKPMFB_01821 8.1e-114 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HIIKPMFB_01822 5e-96 dps P Belongs to the Dps family
HIIKPMFB_01823 3.9e-34 copZ C Heavy-metal-associated domain
HIIKPMFB_01824 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HIIKPMFB_01825 1.1e-62
HIIKPMFB_01826 1.6e-22
HIIKPMFB_01827 9.6e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIIKPMFB_01828 1.5e-245 nhaC C Na H antiporter NhaC
HIIKPMFB_01829 4.1e-56
HIIKPMFB_01830 2.2e-112 ybhL S Belongs to the BI1 family
HIIKPMFB_01831 4.2e-172 yegS 2.7.1.107 G Lipid kinase
HIIKPMFB_01832 1.9e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIIKPMFB_01833 1.5e-261 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HIIKPMFB_01834 2.6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIIKPMFB_01835 1.1e-201 camS S sex pheromone
HIIKPMFB_01836 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HIIKPMFB_01837 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HIIKPMFB_01838 2.8e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HIIKPMFB_01840 4.3e-64 ydcK S Belongs to the SprT family
HIIKPMFB_01841 9.7e-137 M Glycosyltransferase sugar-binding region containing DXD motif
HIIKPMFB_01842 1.1e-256 epsU S Polysaccharide biosynthesis protein
HIIKPMFB_01843 2.9e-226 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HIIKPMFB_01844 0.0 pacL 3.6.3.8 P P-type ATPase
HIIKPMFB_01845 6.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HIIKPMFB_01846 1.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIIKPMFB_01847 1.1e-206 csaB M Glycosyl transferases group 1
HIIKPMFB_01848 8e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HIIKPMFB_01849 1.5e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HIIKPMFB_01850 7.3e-124 gntR1 K UTRA
HIIKPMFB_01851 4e-209
HIIKPMFB_01854 3.9e-276 slpX S SLAP domain
HIIKPMFB_01855 1.3e-177 pfoS S Phosphotransferase system, EIIC
HIIKPMFB_01857 6.1e-70 EGP Major facilitator Superfamily
HIIKPMFB_01858 2.6e-285 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HIIKPMFB_01859 6.5e-212 msmX P Belongs to the ABC transporter superfamily
HIIKPMFB_01860 5.8e-260 sacA 3.2.1.26 GH32 G Glycosyl hydrolases family 32
HIIKPMFB_01861 3.3e-155 msmG G Binding-protein-dependent transport system inner membrane component
HIIKPMFB_01862 4.5e-163 msmF P ABC-type sugar transport systems, permease components
HIIKPMFB_01863 2.7e-249 G Bacterial extracellular solute-binding protein
HIIKPMFB_01864 3.9e-184 msmR K helix_turn _helix lactose operon repressor
HIIKPMFB_01865 5.4e-52 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HIIKPMFB_01866 1e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HIIKPMFB_01867 6.6e-107 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
HIIKPMFB_01868 4.9e-110 5.4.2.11 G Phosphoglycerate mutase family
HIIKPMFB_01869 4.1e-195 D nuclear chromosome segregation
HIIKPMFB_01870 7.8e-70 M LysM domain protein
HIIKPMFB_01871 2.5e-161 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HIIKPMFB_01872 2.1e-252 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIIKPMFB_01873 5.6e-13
HIIKPMFB_01874 3.1e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HIIKPMFB_01875 5.9e-67
HIIKPMFB_01876 5.1e-33
HIIKPMFB_01877 1.3e-69 S Iron-sulphur cluster biosynthesis
HIIKPMFB_01878 1.3e-229 L Belongs to the 'phage' integrase family
HIIKPMFB_01879 2.8e-12
HIIKPMFB_01880 7.7e-186 repB EP Plasmid replication protein
HIIKPMFB_01882 1.9e-211 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HIIKPMFB_01883 6.3e-57
HIIKPMFB_01885 7.1e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HIIKPMFB_01886 3.4e-163 dam2 2.1.1.72 L DNA methyltransferase
HIIKPMFB_01887 0.0 S AAA ATPase domain
HIIKPMFB_01888 0.0 L Type III restriction enzyme, res subunit
HIIKPMFB_01890 6.8e-144 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HIIKPMFB_01891 7.1e-231 amtB P ammonium transporter
HIIKPMFB_01892 4.3e-62
HIIKPMFB_01893 0.0 lhr L DEAD DEAH box helicase
HIIKPMFB_01894 1.4e-253 P P-loop Domain of unknown function (DUF2791)
HIIKPMFB_01895 0.0 S TerB-C domain
HIIKPMFB_01896 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HIIKPMFB_01897 2.1e-70 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HIIKPMFB_01898 1.3e-136 4.1.1.44 S Carboxymuconolactone decarboxylase family
HIIKPMFB_01899 7.3e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIIKPMFB_01900 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HIIKPMFB_01901 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HIIKPMFB_01902 9.2e-248 cycA E Amino acid permease
HIIKPMFB_01903 3.9e-69 S transferase hexapeptide repeat
HIIKPMFB_01904 3.7e-160 K Transcriptional regulator
HIIKPMFB_01905 4e-65 manO S Domain of unknown function (DUF956)
HIIKPMFB_01906 6.3e-176 manN G system, mannose fructose sorbose family IID component
HIIKPMFB_01907 2.5e-136 manY G PTS system
HIIKPMFB_01908 4.2e-189 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HIIKPMFB_01909 2.4e-09 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)