ORF_ID e_value Gene_name EC_number CAZy COGs Description
CMGECGDC_00001 3.8e-162 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
CMGECGDC_00002 2.3e-116 dedA S SNARE-like domain protein
CMGECGDC_00003 1.1e-107 S Protein of unknown function (DUF1461)
CMGECGDC_00004 7.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CMGECGDC_00005 1.3e-81 yutD S Protein of unknown function (DUF1027)
CMGECGDC_00006 5.2e-275 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CMGECGDC_00007 1.9e-55
CMGECGDC_00008 5.7e-266 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CMGECGDC_00009 2.9e-182 ccpA K catabolite control protein A
CMGECGDC_00010 7.5e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CMGECGDC_00011 2.1e-45
CMGECGDC_00012 3.6e-09 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CMGECGDC_00013 8.2e-130 ykuT M mechanosensitive ion channel
CMGECGDC_00014 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CMGECGDC_00015 3.8e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CMGECGDC_00016 2.3e-69 yslB S Protein of unknown function (DUF2507)
CMGECGDC_00017 4e-36 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CMGECGDC_00018 6e-54 trxA O Belongs to the thioredoxin family
CMGECGDC_00019 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CMGECGDC_00020 2.8e-51 yrzB S Belongs to the UPF0473 family
CMGECGDC_00021 2.7e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CMGECGDC_00022 2e-42 yrzL S Belongs to the UPF0297 family
CMGECGDC_00023 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CMGECGDC_00024 3.3e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CMGECGDC_00025 6.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
CMGECGDC_00026 2.2e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMGECGDC_00027 5.3e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CMGECGDC_00028 1.1e-47 yajC U Preprotein translocase
CMGECGDC_00029 4.6e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CMGECGDC_00030 2.7e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CMGECGDC_00031 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CMGECGDC_00032 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CMGECGDC_00033 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CMGECGDC_00034 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CMGECGDC_00035 6.9e-128 liaI S membrane
CMGECGDC_00036 1.1e-77 XK27_02470 K LytTr DNA-binding domain
CMGECGDC_00037 5.8e-75
CMGECGDC_00038 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
CMGECGDC_00039 5.6e-296 scrB 3.2.1.26 GH32 G invertase
CMGECGDC_00040 1e-184 scrR K helix_turn _helix lactose operon repressor
CMGECGDC_00041 3.7e-111 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CMGECGDC_00042 0.0 uup S ABC transporter, ATP-binding protein
CMGECGDC_00043 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
CMGECGDC_00044 4.3e-266 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CMGECGDC_00045 6.5e-234 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CMGECGDC_00046 4.9e-128 yegW K UTRA
CMGECGDC_00047 2.1e-182 S Oxidoreductase family, NAD-binding Rossmann fold
CMGECGDC_00048 1.3e-131 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CMGECGDC_00049 1.1e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CMGECGDC_00050 3.3e-106 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
CMGECGDC_00051 1.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
CMGECGDC_00052 7.6e-86 S ECF transporter, substrate-specific component
CMGECGDC_00053 8.1e-142 fat 3.1.2.21 I Acyl-ACP thioesterase
CMGECGDC_00054 6.7e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CMGECGDC_00055 3e-60 yabA L Involved in initiation control of chromosome replication
CMGECGDC_00056 2.6e-155 holB 2.7.7.7 L DNA polymerase III
CMGECGDC_00057 5.8e-52 yaaQ S Cyclic-di-AMP receptor
CMGECGDC_00058 2.3e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CMGECGDC_00059 1.1e-34 S Protein of unknown function (DUF2508)
CMGECGDC_00060 3.7e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CMGECGDC_00061 2e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CMGECGDC_00062 2.9e-51
CMGECGDC_00063 8.3e-148 K Helix-turn-helix XRE-family like proteins
CMGECGDC_00064 5.6e-126 S Alpha/beta hydrolase family
CMGECGDC_00065 7.3e-160 2.4.1.293 GT2 M Glycosyltransferase like family 2
CMGECGDC_00066 7.7e-137 ypuA S Protein of unknown function (DUF1002)
CMGECGDC_00067 2.2e-142 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMGECGDC_00068 1.9e-180 S Alpha/beta hydrolase of unknown function (DUF915)
CMGECGDC_00069 1.2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMGECGDC_00070 1.7e-84
CMGECGDC_00071 2.3e-133 cobB K SIR2 family
CMGECGDC_00072 2.4e-82 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
CMGECGDC_00073 5.8e-138 terC P Integral membrane protein TerC family
CMGECGDC_00074 2.5e-64 yeaO S Protein of unknown function, DUF488
CMGECGDC_00075 5.5e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
CMGECGDC_00076 1e-293 glnP P ABC transporter permease
CMGECGDC_00077 2.1e-137 glnQ E ABC transporter, ATP-binding protein
CMGECGDC_00078 1.2e-182 S Protein of unknown function (DUF805)
CMGECGDC_00079 4e-161 L HNH nucleases
CMGECGDC_00080 3.7e-122 yfbR S HD containing hydrolase-like enzyme
CMGECGDC_00081 1.5e-211 G Glycosyl hydrolases family 8
CMGECGDC_00082 1.6e-228 ydaM M Glycosyl transferase family group 2
CMGECGDC_00084 1.6e-152
CMGECGDC_00085 1.2e-17
CMGECGDC_00086 1.1e-301 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
CMGECGDC_00087 2.2e-69 S Iron-sulphur cluster biosynthesis
CMGECGDC_00088 2.5e-195 ybiR P Citrate transporter
CMGECGDC_00089 1.4e-93 lemA S LemA family
CMGECGDC_00090 1.6e-163 htpX O Belongs to the peptidase M48B family
CMGECGDC_00091 3.9e-173 K helix_turn_helix, arabinose operon control protein
CMGECGDC_00092 6e-252 cbiO1 S ABC transporter, ATP-binding protein
CMGECGDC_00093 8.9e-92 P Cobalt transport protein
CMGECGDC_00094 1.3e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
CMGECGDC_00095 1.1e-121
CMGECGDC_00096 4.5e-18
CMGECGDC_00097 2.1e-258 S CAAX protease self-immunity
CMGECGDC_00099 2.4e-150 K Helix-turn-helix XRE-family like proteins
CMGECGDC_00100 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CMGECGDC_00101 8.8e-149 htrA 3.4.21.107 O serine protease
CMGECGDC_00102 1.1e-149 vicX 3.1.26.11 S domain protein
CMGECGDC_00103 9.4e-147 yycI S YycH protein
CMGECGDC_00104 1e-259 yycH S YycH protein
CMGECGDC_00105 7.7e-306 vicK 2.7.13.3 T Histidine kinase
CMGECGDC_00106 9.7e-132 K response regulator
CMGECGDC_00109 1.4e-295 V ABC-type multidrug transport system, ATPase and permease components
CMGECGDC_00110 2.8e-288 P ABC transporter
CMGECGDC_00111 3e-78
CMGECGDC_00112 2.1e-148 arbV 2.3.1.51 I Acyl-transferase
CMGECGDC_00113 1.1e-158 arbx M Glycosyl transferase family 8
CMGECGDC_00114 2.2e-187 arbY M Glycosyl transferase family 8
CMGECGDC_00115 8.4e-184 arbY M Glycosyl transferase family 8
CMGECGDC_00116 5e-167 arbZ I Phosphate acyltransferases
CMGECGDC_00117 1.5e-38 S Cytochrome B5
CMGECGDC_00118 5.6e-115 K Transcriptional regulator, LysR family
CMGECGDC_00119 3.7e-229 1.3.5.4 C FAD binding domain
CMGECGDC_00120 4.2e-56 1.3.5.4 S FMN_bind
CMGECGDC_00121 2.2e-51 K LysR substrate binding domain
CMGECGDC_00122 2e-33 K LysR substrate binding domain
CMGECGDC_00123 1.8e-253 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CMGECGDC_00124 1.4e-101 J Acetyltransferase (GNAT) domain
CMGECGDC_00125 2.7e-111 yjbF S SNARE associated Golgi protein
CMGECGDC_00126 5.5e-152 I alpha/beta hydrolase fold
CMGECGDC_00127 4.5e-160 hipB K Helix-turn-helix
CMGECGDC_00128 2.1e-93 F Nucleoside 2-deoxyribosyltransferase
CMGECGDC_00129 2.1e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
CMGECGDC_00130 0.0 fhaB M Rib/alpha-like repeat
CMGECGDC_00131 0.0 fhaB M Rib/alpha-like repeat
CMGECGDC_00132 2.4e-163
CMGECGDC_00133 0.0 ydgH S MMPL family
CMGECGDC_00134 2.3e-96 yobS K Bacterial regulatory proteins, tetR family
CMGECGDC_00135 1.5e-148 3.5.2.6 V Beta-lactamase enzyme family
CMGECGDC_00136 4e-154 corA P CorA-like Mg2+ transporter protein
CMGECGDC_00137 1.3e-235 G Bacterial extracellular solute-binding protein
CMGECGDC_00138 3.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
CMGECGDC_00139 9.4e-147 gtsC P Binding-protein-dependent transport system inner membrane component
CMGECGDC_00140 2.3e-57 gtsB P ABC-type sugar transport systems, permease components
CMGECGDC_00141 1.9e-65 gtsB P ABC-type sugar transport systems, permease components
CMGECGDC_00142 7.1e-203 malK P ATPases associated with a variety of cellular activities
CMGECGDC_00143 2.8e-284 pipD E Dipeptidase
CMGECGDC_00144 1.6e-157 endA F DNA RNA non-specific endonuclease
CMGECGDC_00145 1.9e-183 dnaQ 2.7.7.7 L EXOIII
CMGECGDC_00146 1.4e-155 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CMGECGDC_00147 7.3e-115 yviA S Protein of unknown function (DUF421)
CMGECGDC_00148 3.4e-74 S Protein of unknown function (DUF3290)
CMGECGDC_00149 0.0 sdrF M domain protein
CMGECGDC_00150 4.5e-140 pnuC H nicotinamide mononucleotide transporter
CMGECGDC_00151 6.2e-264
CMGECGDC_00152 3.5e-48
CMGECGDC_00153 1.5e-143 S PAS domain
CMGECGDC_00154 4.8e-296 V ABC transporter transmembrane region
CMGECGDC_00155 1.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
CMGECGDC_00156 1.8e-127 T Transcriptional regulatory protein, C terminal
CMGECGDC_00157 5.4e-245 T GHKL domain
CMGECGDC_00158 2.1e-86 S Peptidase propeptide and YPEB domain
CMGECGDC_00159 2.3e-97 S Peptidase propeptide and YPEB domain
CMGECGDC_00160 2.8e-76 yybA 2.3.1.57 K Transcriptional regulator
CMGECGDC_00161 6.8e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
CMGECGDC_00162 0.0 E ABC transporter, substratebinding protein
CMGECGDC_00163 1.1e-54 ypaA S Protein of unknown function (DUF1304)
CMGECGDC_00164 4.6e-100 S Peptidase propeptide and YPEB domain
CMGECGDC_00165 9.9e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMGECGDC_00166 3.5e-171 coaA 2.7.1.33 F Pantothenic acid kinase
CMGECGDC_00167 6.7e-104 E GDSL-like Lipase/Acylhydrolase
CMGECGDC_00168 9.9e-82 yjcF S Acetyltransferase (GNAT) domain
CMGECGDC_00169 2.8e-151 aatB ET ABC transporter substrate-binding protein
CMGECGDC_00170 9e-110 glnQ 3.6.3.21 E ABC transporter
CMGECGDC_00171 3e-108 glnP P ABC transporter permease
CMGECGDC_00172 0.0 helD 3.6.4.12 L DNA helicase
CMGECGDC_00173 9.9e-126 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
CMGECGDC_00174 8.5e-127 pgm3 5.4.2.11 G Phosphoglycerate mutase family
CMGECGDC_00175 0.0 V FtsX-like permease family
CMGECGDC_00176 1.7e-134 cysA V ABC transporter, ATP-binding protein
CMGECGDC_00177 1.6e-241 S response to antibiotic
CMGECGDC_00178 1.1e-127
CMGECGDC_00179 0.0 3.6.3.8 P P-type ATPase
CMGECGDC_00180 2.1e-64 2.7.1.191 G PTS system fructose IIA component
CMGECGDC_00181 2.1e-48
CMGECGDC_00182 1.9e-15
CMGECGDC_00183 4.2e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
CMGECGDC_00184 1.5e-138 glvR K Helix-turn-helix domain, rpiR family
CMGECGDC_00185 4.1e-269 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
CMGECGDC_00186 4.3e-155
CMGECGDC_00187 3.4e-91
CMGECGDC_00188 4.2e-106 3.2.2.20 K acetyltransferase
CMGECGDC_00191 4.4e-311 asdA 4.1.1.12 E Aminotransferase
CMGECGDC_00192 3.2e-303 aspT P Predicted Permease Membrane Region
CMGECGDC_00193 4.2e-189 S Domain of unknown function (DUF4767)
CMGECGDC_00194 2.5e-184 S Membrane
CMGECGDC_00195 6.4e-150 xth 3.1.11.2 L exodeoxyribonuclease III
CMGECGDC_00196 7.9e-188 K helix_turn_helix, arabinose operon control protein
CMGECGDC_00197 5.1e-187 K helix_turn_helix, arabinose operon control protein
CMGECGDC_00198 4.7e-149 K Helix-turn-helix domain, rpiR family
CMGECGDC_00199 7.7e-202 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
CMGECGDC_00200 3.7e-157 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CMGECGDC_00201 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMGECGDC_00202 1.6e-298 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMGECGDC_00203 0.0 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMGECGDC_00204 2.5e-158 K CAT RNA binding domain
CMGECGDC_00205 0.0 M Leucine-rich repeat (LRR) protein
CMGECGDC_00206 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CMGECGDC_00207 1.2e-91
CMGECGDC_00208 1.6e-182
CMGECGDC_00209 9.7e-271 S Uncharacterised protein conserved in bacteria (DUF2326)
CMGECGDC_00210 7.6e-10
CMGECGDC_00216 2.2e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CMGECGDC_00217 4.1e-217 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CMGECGDC_00218 2.3e-63 L PFAM Integrase catalytic region
CMGECGDC_00219 1e-136 L transposase activity
CMGECGDC_00220 5.2e-234 L COG3547 Transposase and inactivated derivatives
CMGECGDC_00221 4.6e-266 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
CMGECGDC_00222 1.2e-200 glf 5.4.99.9 M UDP-galactopyranose mutase
CMGECGDC_00223 4.2e-218 S Psort location CytoplasmicMembrane, score 9.99
CMGECGDC_00224 1.2e-188 M Glycosyltransferase like family 2
CMGECGDC_00225 5.7e-118 M transferase activity, transferring glycosyl groups
CMGECGDC_00226 2.5e-166 glfT1 1.1.1.133 S Glycosyltransferase like family 2
CMGECGDC_00227 1.6e-148 cps1D M Domain of unknown function (DUF4422)
CMGECGDC_00228 1.1e-123 rfbP M Bacterial sugar transferase
CMGECGDC_00229 3.6e-148 ywqE 3.1.3.48 GM PHP domain protein
CMGECGDC_00230 1.2e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
CMGECGDC_00231 1.6e-141 epsB M biosynthesis protein
CMGECGDC_00232 4e-174 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CMGECGDC_00233 4e-205 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CMGECGDC_00234 3.2e-189 S Cysteine-rich secretory protein family
CMGECGDC_00235 0.0 2.7.13.3 M Mycoplasma protein of unknown function, DUF285
CMGECGDC_00236 3.7e-128 M NlpC/P60 family
CMGECGDC_00237 2.3e-126 M NlpC P60 family protein
CMGECGDC_00238 7.6e-84 M NlpC/P60 family
CMGECGDC_00239 1.5e-84 gmk2 2.7.4.8 F Guanylate kinase homologues.
CMGECGDC_00240 5.6e-33
CMGECGDC_00241 1e-279 S O-antigen ligase like membrane protein
CMGECGDC_00242 8.1e-111
CMGECGDC_00243 3.8e-78 nrdI F NrdI Flavodoxin like
CMGECGDC_00244 1e-18 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMGECGDC_00245 1.6e-137 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMGECGDC_00246 7.8e-78
CMGECGDC_00247 7.7e-137 yvpB S Peptidase_C39 like family
CMGECGDC_00248 5.2e-53 yitW S Iron-sulfur cluster assembly protein
CMGECGDC_00249 8.8e-47 sufB O assembly protein SufB
CMGECGDC_00250 4.6e-35 sufC O FeS assembly ATPase SufC
CMGECGDC_00251 7.8e-85 S Threonine/Serine exporter, ThrE
CMGECGDC_00252 4.4e-138 thrE S Putative threonine/serine exporter
CMGECGDC_00253 2.1e-293 S ABC transporter
CMGECGDC_00254 3.6e-61
CMGECGDC_00255 2.2e-45 rimL J Acetyltransferase (GNAT) domain
CMGECGDC_00256 1.5e-223 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CMGECGDC_00257 0.0 pepF E oligoendopeptidase F
CMGECGDC_00258 6.7e-44 P transmembrane transport
CMGECGDC_00259 7e-265 lctP C L-lactate permease
CMGECGDC_00260 1.4e-62 pdxH S Pyridoxamine 5'-phosphate oxidase
CMGECGDC_00261 7.9e-135 znuB U ABC 3 transport family
CMGECGDC_00262 1e-116 fhuC P ABC transporter
CMGECGDC_00263 6.4e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
CMGECGDC_00264 2.5e-43 K helix_turn_helix, Arsenical Resistance Operon Repressor
CMGECGDC_00265 5.1e-75 K LytTr DNA-binding domain
CMGECGDC_00266 5.5e-47 S Protein of unknown function (DUF3021)
CMGECGDC_00267 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
CMGECGDC_00268 3.3e-169 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CMGECGDC_00269 2.3e-136 fruR K DeoR C terminal sensor domain
CMGECGDC_00270 4.8e-196 fic S Fic/DOC family
CMGECGDC_00271 3.9e-218 natB CP ABC-2 family transporter protein
CMGECGDC_00272 2.6e-166 natA S ABC transporter, ATP-binding protein
CMGECGDC_00273 6.2e-08
CMGECGDC_00274 4e-69
CMGECGDC_00275 2.1e-25
CMGECGDC_00276 8.2e-31 yozG K Transcriptional regulator
CMGECGDC_00277 9e-90
CMGECGDC_00278 8.8e-21
CMGECGDC_00283 8.1e-209 blpT
CMGECGDC_00284 3.4e-106 M Transport protein ComB
CMGECGDC_00285 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CMGECGDC_00286 4.2e-07
CMGECGDC_00288 1.2e-146 K LytTr DNA-binding domain
CMGECGDC_00289 1.4e-232 2.7.13.3 T GHKL domain
CMGECGDC_00293 7.4e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CMGECGDC_00294 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CMGECGDC_00295 7.5e-25 secG U Preprotein translocase
CMGECGDC_00296 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CMGECGDC_00297 4.7e-180 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CMGECGDC_00298 2.9e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
CMGECGDC_00299 2.3e-223 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
CMGECGDC_00311 1.6e-45 L Helicase C-terminal domain protein
CMGECGDC_00312 0.0 L Helicase C-terminal domain protein
CMGECGDC_00313 7.1e-74 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
CMGECGDC_00330 3.2e-172 L Putative transposase DNA-binding domain
CMGECGDC_00331 1.2e-188 lacR K Transcriptional regulator
CMGECGDC_00332 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
CMGECGDC_00333 4.3e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
CMGECGDC_00334 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CMGECGDC_00335 4.7e-309 2.7.7.7 S Domain of unknown function (DUF5060)
CMGECGDC_00336 1.3e-216 uhpT EGP Major facilitator Superfamily
CMGECGDC_00337 2.1e-174 rbsR K helix_turn _helix lactose operon repressor
CMGECGDC_00338 0.0 3.2.1.40 G Alpha-L-rhamnosidase N-terminal domain
CMGECGDC_00339 8.1e-60 G polysaccharide catabolic process
CMGECGDC_00340 2.4e-09 L Transposase
CMGECGDC_00341 1e-78 G YdjC-like protein
CMGECGDC_00342 7.3e-177 I alpha/beta hydrolase fold
CMGECGDC_00343 0.0 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMGECGDC_00344 5.7e-155 licT K CAT RNA binding domain
CMGECGDC_00345 2.4e-258 G Protein of unknown function (DUF4038)
CMGECGDC_00346 5.7e-175 rbsB G Periplasmic binding protein domain
CMGECGDC_00347 2e-147 rbsC U Belongs to the binding-protein-dependent transport system permease family
CMGECGDC_00349 2.7e-277 rbsA 3.6.3.17 G ABC transporter
CMGECGDC_00350 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CMGECGDC_00351 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CMGECGDC_00352 1.7e-289 G isomerase
CMGECGDC_00353 4.2e-189 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
CMGECGDC_00354 9.5e-136 manY G PTS system
CMGECGDC_00355 6.3e-176 manN G system, mannose fructose sorbose family IID component
CMGECGDC_00356 4e-65 manO S Domain of unknown function (DUF956)
CMGECGDC_00357 3.7e-160 K Transcriptional regulator
CMGECGDC_00358 3.9e-69 S transferase hexapeptide repeat
CMGECGDC_00359 9.2e-248 cycA E Amino acid permease
CMGECGDC_00360 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CMGECGDC_00361 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CMGECGDC_00362 7.3e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMGECGDC_00363 1.3e-136 4.1.1.44 S Carboxymuconolactone decarboxylase family
CMGECGDC_00364 2.1e-70 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
CMGECGDC_00365 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
CMGECGDC_00366 0.0 S TerB-C domain
CMGECGDC_00367 1.4e-253 P P-loop Domain of unknown function (DUF2791)
CMGECGDC_00368 0.0 lhr L DEAD DEAH box helicase
CMGECGDC_00369 4.3e-62
CMGECGDC_00370 7.1e-231 amtB P ammonium transporter
CMGECGDC_00371 6.8e-144 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CMGECGDC_00373 1.3e-69 S Iron-sulphur cluster biosynthesis
CMGECGDC_00374 5.1e-33
CMGECGDC_00375 5.9e-67
CMGECGDC_00376 3.1e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
CMGECGDC_00377 5.6e-13
CMGECGDC_00378 2.1e-252 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMGECGDC_00379 2.5e-161 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CMGECGDC_00380 7.8e-70 M LysM domain protein
CMGECGDC_00381 4.1e-195 D nuclear chromosome segregation
CMGECGDC_00382 4.9e-110 5.4.2.11 G Phosphoglycerate mutase family
CMGECGDC_00383 6.6e-107 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
CMGECGDC_00384 1e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
CMGECGDC_00385 5.4e-52 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CMGECGDC_00386 3.9e-184 msmR K helix_turn _helix lactose operon repressor
CMGECGDC_00387 2.7e-249 G Bacterial extracellular solute-binding protein
CMGECGDC_00388 4.5e-163 msmF P ABC-type sugar transport systems, permease components
CMGECGDC_00389 3.3e-155 msmG G Binding-protein-dependent transport system inner membrane component
CMGECGDC_00390 5.8e-260 sacA 3.2.1.26 GH32 G Glycosyl hydrolases family 32
CMGECGDC_00391 6.5e-212 msmX P Belongs to the ABC transporter superfamily
CMGECGDC_00392 2.6e-285 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
CMGECGDC_00393 6.1e-70 EGP Major facilitator Superfamily
CMGECGDC_00395 1.3e-177 pfoS S Phosphotransferase system, EIIC
CMGECGDC_00396 3.9e-276 slpX S SLAP domain
CMGECGDC_00399 7.5e-208
CMGECGDC_00400 7.3e-124 gntR1 K UTRA
CMGECGDC_00401 1.5e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
CMGECGDC_00402 8e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CMGECGDC_00403 1.1e-206 csaB M Glycosyl transferases group 1
CMGECGDC_00404 1.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CMGECGDC_00405 6.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CMGECGDC_00406 0.0 pacL 3.6.3.8 P P-type ATPase
CMGECGDC_00407 3.2e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CMGECGDC_00408 1.1e-256 epsU S Polysaccharide biosynthesis protein
CMGECGDC_00409 9.7e-137 M Glycosyltransferase sugar-binding region containing DXD motif
CMGECGDC_00410 4.3e-64 ydcK S Belongs to the SprT family
CMGECGDC_00412 2.8e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
CMGECGDC_00413 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CMGECGDC_00414 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CMGECGDC_00415 1.1e-201 camS S sex pheromone
CMGECGDC_00416 2.6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMGECGDC_00417 1.5e-261 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CMGECGDC_00418 1.9e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMGECGDC_00419 1.6e-171 yegS 2.7.1.107 G Lipid kinase
CMGECGDC_00420 2.2e-112 ybhL S Belongs to the BI1 family
CMGECGDC_00421 4.1e-56
CMGECGDC_00422 1.5e-245 nhaC C Na H antiporter NhaC
CMGECGDC_00423 9.6e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMGECGDC_00424 1.6e-22
CMGECGDC_00425 1.1e-62
CMGECGDC_00426 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
CMGECGDC_00427 3.9e-34 copZ C Heavy-metal-associated domain
CMGECGDC_00428 5e-96 dps P Belongs to the Dps family
CMGECGDC_00429 6.8e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
CMGECGDC_00430 2.8e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
CMGECGDC_00431 1.2e-48 5.1.1.13 M Asp/Glu/Hydantoin racemase
CMGECGDC_00432 6.5e-57 5.1.1.13 M Asp/Glu/Hydantoin racemase
CMGECGDC_00433 9e-192 L Recombinase
CMGECGDC_00434 7.8e-94 L Resolvase, N terminal domain
CMGECGDC_00435 1.4e-178 L Recombinase zinc beta ribbon domain
CMGECGDC_00436 6.6e-95 MA20_25245 K Acetyltransferase (GNAT) domain
CMGECGDC_00441 3.9e-244 emrY EGP Major facilitator Superfamily
CMGECGDC_00442 6.8e-136 S CAAX protease self-immunity
CMGECGDC_00443 5e-90 yxdD K Bacterial regulatory proteins, tetR family
CMGECGDC_00444 0.0 4.2.1.53 S Myosin-crossreactive antigen
CMGECGDC_00445 8.4e-78 2.3.1.128 K acetyltransferase
CMGECGDC_00446 8e-162 S reductase
CMGECGDC_00447 3.6e-109 V ABC-type multidrug transport system, ATPase and permease components
CMGECGDC_00448 5.1e-128 cydD V cysteine transport
CMGECGDC_00449 2.1e-241 pyrP F Permease
CMGECGDC_00450 9.5e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMGECGDC_00451 1.5e-86 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CMGECGDC_00452 2.4e-50 3.1.3.102, 3.1.3.104 Q phosphatase activity
CMGECGDC_00453 1.6e-253 emrY EGP Major facilitator Superfamily
CMGECGDC_00454 4e-215 mdtG EGP Major facilitator Superfamily
CMGECGDC_00455 1.8e-165 mleP3 S Membrane transport protein
CMGECGDC_00456 2.1e-210 pepA E M42 glutamyl aminopeptidase
CMGECGDC_00457 0.0 ybiT S ABC transporter, ATP-binding protein
CMGECGDC_00458 9.8e-146
CMGECGDC_00459 9e-150 glnH ET ABC transporter
CMGECGDC_00460 2.3e-78 K Transcriptional regulator, MarR family
CMGECGDC_00461 7.1e-306 XK27_09600 V ABC transporter, ATP-binding protein
CMGECGDC_00462 0.0 V ABC transporter transmembrane region
CMGECGDC_00463 2.9e-102 S ABC-type cobalt transport system, permease component
CMGECGDC_00464 8e-114 udk 2.7.1.48 F Zeta toxin
CMGECGDC_00465 7.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CMGECGDC_00466 1.3e-148 glnH ET ABC transporter substrate-binding protein
CMGECGDC_00467 6.1e-93 gluC P ABC transporter permease
CMGECGDC_00468 1.9e-110 glnP P ABC transporter permease
CMGECGDC_00469 1.5e-174 S Protein of unknown function (DUF2974)
CMGECGDC_00470 1.2e-63
CMGECGDC_00471 4.8e-238 G Bacterial extracellular solute-binding protein
CMGECGDC_00472 4.1e-163 2.7.7.12 C Domain of unknown function (DUF4931)
CMGECGDC_00473 5.9e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CMGECGDC_00474 2e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CMGECGDC_00475 0.0 kup P Transport of potassium into the cell
CMGECGDC_00476 6.3e-176 rihB 3.2.2.1 F Nucleoside
CMGECGDC_00477 3.3e-135 gntR K UbiC transcription regulator-associated domain protein
CMGECGDC_00478 2.6e-22
CMGECGDC_00479 1.2e-112
CMGECGDC_00480 2.9e-285 V ABC transporter transmembrane region
CMGECGDC_00481 1.8e-153 S hydrolase
CMGECGDC_00482 5.3e-72 K helix_turn_helix multiple antibiotic resistance protein
CMGECGDC_00483 0.0 lmrA 3.6.3.44 V ABC transporter
CMGECGDC_00484 1.9e-59 S Enterocin A Immunity
CMGECGDC_00485 1.3e-137 glcR K DeoR C terminal sensor domain
CMGECGDC_00486 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
CMGECGDC_00487 2.6e-160 rssA S Phospholipase, patatin family
CMGECGDC_00488 3.8e-224 2.7.13.3 T GHKL domain
CMGECGDC_00489 5e-145 K LytTr DNA-binding domain
CMGECGDC_00490 3.4e-222 S CAAX protease self-immunity
CMGECGDC_00491 2.3e-153 S hydrolase
CMGECGDC_00492 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
CMGECGDC_00493 7.6e-149 glvR K Helix-turn-helix domain, rpiR family
CMGECGDC_00494 2.9e-82
CMGECGDC_00495 1.1e-86 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CMGECGDC_00496 1.9e-40
CMGECGDC_00497 6e-120 C nitroreductase
CMGECGDC_00498 1.1e-248 yhdP S Transporter associated domain
CMGECGDC_00499 2.2e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CMGECGDC_00500 1.5e-228 potE E amino acid
CMGECGDC_00501 1.1e-130 M Glycosyl hydrolases family 25
CMGECGDC_00502 2.6e-209 yfmL 3.6.4.13 L DEAD DEAH box helicase
CMGECGDC_00503 1.2e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMGECGDC_00506 4.1e-217 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CMGECGDC_00507 4.3e-89 gtcA S Teichoic acid glycosylation protein
CMGECGDC_00508 1.2e-79 fld C Flavodoxin
CMGECGDC_00509 1.1e-163 map 3.4.11.18 E Methionine Aminopeptidase
CMGECGDC_00510 4.1e-151 yihY S Belongs to the UPF0761 family
CMGECGDC_00511 3.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CMGECGDC_00512 5.1e-215 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
CMGECGDC_00513 4.6e-219 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
CMGECGDC_00514 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
CMGECGDC_00515 1.9e-46
CMGECGDC_00516 1.5e-177 D Alpha beta
CMGECGDC_00517 6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMGECGDC_00518 1.7e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
CMGECGDC_00519 9.1e-86
CMGECGDC_00520 1.2e-71
CMGECGDC_00521 9.5e-158 hlyX S Transporter associated domain
CMGECGDC_00522 1e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CMGECGDC_00523 6.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
CMGECGDC_00524 0.0 clpE O Belongs to the ClpA ClpB family
CMGECGDC_00525 8.5e-41 ptsH G phosphocarrier protein HPR
CMGECGDC_00526 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CMGECGDC_00527 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CMGECGDC_00528 8.8e-128 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CMGECGDC_00529 1.4e-161 coiA 3.6.4.12 S Competence protein
CMGECGDC_00530 1.2e-114 yjbH Q Thioredoxin
CMGECGDC_00531 9.5e-112 yjbK S CYTH
CMGECGDC_00532 2.3e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
CMGECGDC_00533 1.6e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CMGECGDC_00534 8.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMGECGDC_00535 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
CMGECGDC_00536 2e-118 S SNARE associated Golgi protein
CMGECGDC_00537 1.7e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
CMGECGDC_00538 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
CMGECGDC_00539 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
CMGECGDC_00540 3.2e-212 yubA S AI-2E family transporter
CMGECGDC_00541 1.3e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CMGECGDC_00542 1.8e-68 WQ51_03320 S Protein of unknown function (DUF1149)
CMGECGDC_00543 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CMGECGDC_00544 3.5e-227 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
CMGECGDC_00545 4.5e-241 S Peptidase M16
CMGECGDC_00546 2e-132 IQ Enoyl-(Acyl carrier protein) reductase
CMGECGDC_00547 6.6e-119 ymfM S Helix-turn-helix domain
CMGECGDC_00548 9.3e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMGECGDC_00549 7.9e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CMGECGDC_00550 9.6e-220 rny S Endoribonuclease that initiates mRNA decay
CMGECGDC_00551 1.8e-212 tagO 2.7.8.33, 2.7.8.35 M transferase
CMGECGDC_00552 9.6e-118 yvyE 3.4.13.9 S YigZ family
CMGECGDC_00553 3.3e-247 comFA L Helicase C-terminal domain protein
CMGECGDC_00554 3.1e-135 comFC S Competence protein
CMGECGDC_00555 5.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CMGECGDC_00556 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CMGECGDC_00557 3.5e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CMGECGDC_00559 5.4e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CMGECGDC_00560 1.4e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CMGECGDC_00561 6.1e-188 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CMGECGDC_00562 1.2e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CMGECGDC_00563 5.9e-41 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CMGECGDC_00564 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CMGECGDC_00565 2.9e-223 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CMGECGDC_00566 7.2e-214 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
CMGECGDC_00567 2.8e-287 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
CMGECGDC_00568 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CMGECGDC_00569 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
CMGECGDC_00570 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CMGECGDC_00571 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CMGECGDC_00572 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CMGECGDC_00573 1.1e-90 S Short repeat of unknown function (DUF308)
CMGECGDC_00574 4.8e-165 rapZ S Displays ATPase and GTPase activities
CMGECGDC_00575 8.1e-196 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CMGECGDC_00576 6.8e-170 whiA K May be required for sporulation
CMGECGDC_00577 4.7e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CMGECGDC_00578 0.0 S SH3-like domain
CMGECGDC_00579 1.3e-276 ycaM E amino acid
CMGECGDC_00581 8.6e-190 cggR K Putative sugar-binding domain
CMGECGDC_00582 3.8e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CMGECGDC_00583 3.5e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CMGECGDC_00584 9.9e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CMGECGDC_00585 1.3e-96
CMGECGDC_00586 3.1e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
CMGECGDC_00587 2.6e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CMGECGDC_00588 1.8e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CMGECGDC_00589 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
CMGECGDC_00590 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
CMGECGDC_00591 2.4e-164 murB 1.3.1.98 M Cell wall formation
CMGECGDC_00592 9.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CMGECGDC_00593 1.1e-136 potB P ABC transporter permease
CMGECGDC_00594 2.9e-132 potC P ABC transporter permease
CMGECGDC_00595 4e-206 potD P ABC transporter
CMGECGDC_00596 1.1e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CMGECGDC_00597 1.2e-172 ybbR S YbbR-like protein
CMGECGDC_00598 3.9e-259 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CMGECGDC_00599 1.3e-148 S hydrolase
CMGECGDC_00600 1.3e-145 S Sucrose-6F-phosphate phosphohydrolase
CMGECGDC_00601 1e-120
CMGECGDC_00602 1.7e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CMGECGDC_00603 6.7e-212 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CMGECGDC_00604 3.4e-152 licT K CAT RNA binding domain
CMGECGDC_00605 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMGECGDC_00606 3.1e-286 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMGECGDC_00607 4.2e-175 D Alpha beta
CMGECGDC_00608 0.0 E Amino acid permease
CMGECGDC_00610 2.2e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMGECGDC_00611 1.9e-92 S VanZ like family
CMGECGDC_00612 2e-132 yebC K Transcriptional regulatory protein
CMGECGDC_00613 5.4e-178 comGA NU Type II IV secretion system protein
CMGECGDC_00614 9.9e-175 comGB NU type II secretion system
CMGECGDC_00615 2.4e-46 comGC U competence protein ComGC
CMGECGDC_00616 2e-71
CMGECGDC_00617 1e-19
CMGECGDC_00618 1.3e-86 comGF U Putative Competence protein ComGF
CMGECGDC_00619 3e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
CMGECGDC_00620 2.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMGECGDC_00622 4.3e-121 M Protein of unknown function (DUF3737)
CMGECGDC_00623 8.1e-176 patB 4.4.1.8 E Aminotransferase, class I
CMGECGDC_00624 5.7e-29 4.4.1.8 E Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CMGECGDC_00625 2.3e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
CMGECGDC_00626 4.9e-61 S SdpI/YhfL protein family
CMGECGDC_00627 2.4e-130 K Transcriptional regulatory protein, C terminal
CMGECGDC_00628 6.2e-271 T PhoQ Sensor
CMGECGDC_00629 1.6e-61 limB 1.14.13.107, 1.14.13.162 C Luciferase-like monooxygenase
CMGECGDC_00630 2.2e-123 XK27_00915 C Luciferase-like monooxygenase
CMGECGDC_00631 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CMGECGDC_00632 4.1e-107 vanZ V VanZ like family
CMGECGDC_00633 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
CMGECGDC_00634 9.9e-250 EGP Major facilitator Superfamily
CMGECGDC_00635 1.3e-110 ampC V Beta-lactamase
CMGECGDC_00636 3.3e-36 ampC V Beta-lactamase
CMGECGDC_00639 2e-64
CMGECGDC_00640 2.9e-287 S DNA primase
CMGECGDC_00641 1.6e-35
CMGECGDC_00642 1.9e-33
CMGECGDC_00643 8.1e-69
CMGECGDC_00644 1.4e-36
CMGECGDC_00645 2.9e-12 S Helix-turn-helix domain
CMGECGDC_00646 3.2e-58 K Transcriptional
CMGECGDC_00647 5.8e-219 sip L Belongs to the 'phage' integrase family
CMGECGDC_00648 2e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
CMGECGDC_00649 4.5e-114 tdk 2.7.1.21 F thymidine kinase
CMGECGDC_00650 3.4e-181 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CMGECGDC_00651 7.8e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CMGECGDC_00652 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CMGECGDC_00653 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CMGECGDC_00654 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
CMGECGDC_00655 6.6e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMGECGDC_00656 1.7e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CMGECGDC_00657 1.5e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMGECGDC_00658 2.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CMGECGDC_00659 9.8e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CMGECGDC_00660 2.1e-255 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CMGECGDC_00661 6.9e-64 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CMGECGDC_00662 2.6e-30 ywzB S Protein of unknown function (DUF1146)
CMGECGDC_00663 1.9e-178 mbl D Cell shape determining protein MreB Mrl
CMGECGDC_00664 2.5e-49 yidD S Could be involved in insertion of integral membrane proteins into the membrane
CMGECGDC_00665 1.5e-33 S Protein of unknown function (DUF2969)
CMGECGDC_00666 9.5e-217 rodA D Belongs to the SEDS family
CMGECGDC_00667 5.8e-77 uspA T universal stress protein
CMGECGDC_00668 4e-33
CMGECGDC_00669 4.2e-242 rarA L recombination factor protein RarA
CMGECGDC_00670 1.9e-83 yueI S Protein of unknown function (DUF1694)
CMGECGDC_00671 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CMGECGDC_00672 1.5e-292 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CMGECGDC_00673 1.1e-217 iscS2 2.8.1.7 E Aminotransferase class V
CMGECGDC_00674 1.7e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CMGECGDC_00675 2.2e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CMGECGDC_00676 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CMGECGDC_00677 8.5e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CMGECGDC_00678 8.9e-127 S Haloacid dehalogenase-like hydrolase
CMGECGDC_00679 1.2e-114 radC L DNA repair protein
CMGECGDC_00680 1.1e-176 mreB D cell shape determining protein MreB
CMGECGDC_00681 7.2e-150 mreC M Involved in formation and maintenance of cell shape
CMGECGDC_00682 7.1e-95 mreD
CMGECGDC_00683 8.8e-10 S Protein of unknown function (DUF4044)
CMGECGDC_00684 3.2e-53 S Protein of unknown function (DUF3397)
CMGECGDC_00685 4e-72 mraZ K Belongs to the MraZ family
CMGECGDC_00686 2.2e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CMGECGDC_00687 2.4e-54 ftsL D Cell division protein FtsL
CMGECGDC_00688 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
CMGECGDC_00689 2.1e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CMGECGDC_00690 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CMGECGDC_00691 4e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMGECGDC_00692 1.2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CMGECGDC_00693 9.4e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CMGECGDC_00694 4.2e-245 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CMGECGDC_00695 2.1e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CMGECGDC_00696 2.5e-41 yggT S YGGT family
CMGECGDC_00697 6.7e-150 ylmH S S4 domain protein
CMGECGDC_00698 1.9e-75 gpsB D DivIVA domain protein
CMGECGDC_00699 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CMGECGDC_00700 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
CMGECGDC_00701 7.5e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
CMGECGDC_00702 3.4e-28
CMGECGDC_00703 5.9e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CMGECGDC_00704 9.8e-58 XK27_04120 S Putative amino acid metabolism
CMGECGDC_00705 9.3e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CMGECGDC_00706 4.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
CMGECGDC_00707 5.7e-115 S Repeat protein
CMGECGDC_00708 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CMGECGDC_00709 3.7e-304 L Nuclease-related domain
CMGECGDC_00710 9.3e-183 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
CMGECGDC_00711 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMGECGDC_00712 3.2e-33 ykzG S Belongs to the UPF0356 family
CMGECGDC_00713 1.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CMGECGDC_00714 0.0 typA T GTP-binding protein TypA
CMGECGDC_00715 8.6e-210 ftsW D Belongs to the SEDS family
CMGECGDC_00716 4.3e-53 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
CMGECGDC_00717 4.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
CMGECGDC_00718 6.2e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CMGECGDC_00719 7.6e-194 ylbL T Belongs to the peptidase S16 family
CMGECGDC_00720 1.7e-72 comEA L Competence protein ComEA
CMGECGDC_00721 0.0 comEC S Competence protein ComEC
CMGECGDC_00722 8.8e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
CMGECGDC_00723 3e-35 rpsT J Binds directly to 16S ribosomal RNA
CMGECGDC_00724 1.1e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CMGECGDC_00725 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMGECGDC_00726 2.2e-151
CMGECGDC_00727 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CMGECGDC_00728 3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CMGECGDC_00729 1.2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CMGECGDC_00730 2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
CMGECGDC_00731 8.9e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CMGECGDC_00732 2.5e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
CMGECGDC_00733 2.9e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CMGECGDC_00734 5.7e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CMGECGDC_00735 2.8e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CMGECGDC_00736 3.7e-176 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CMGECGDC_00737 3.9e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CMGECGDC_00738 5.3e-220 aspC 2.6.1.1 E Aminotransferase
CMGECGDC_00739 5.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CMGECGDC_00740 9.2e-206 pbpX1 V Beta-lactamase
CMGECGDC_00741 1.3e-298 I Protein of unknown function (DUF2974)
CMGECGDC_00742 8.6e-41 C FMN_bind
CMGECGDC_00743 1.6e-80
CMGECGDC_00744 1.9e-286
CMGECGDC_00745 5.2e-178 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
CMGECGDC_00746 2.7e-16 adhC 1.1.1.90 C S-(hydroxymethyl)glutathione dehydrogenase activity
CMGECGDC_00747 8.5e-145
CMGECGDC_00748 2.7e-10
CMGECGDC_00751 6.1e-19 alkD L DNA alkylation repair enzyme
CMGECGDC_00752 1.5e-67 alkD L DNA alkylation repair enzyme
CMGECGDC_00753 6e-39 S Transglycosylase associated protein
CMGECGDC_00755 2.4e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMGECGDC_00756 2.2e-128 K UTRA domain
CMGECGDC_00757 4.5e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
CMGECGDC_00758 4.3e-59 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
CMGECGDC_00759 1.2e-80
CMGECGDC_00760 4.4e-138 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMGECGDC_00761 1.2e-70 S Domain of unknown function (DUF3284)
CMGECGDC_00762 6.3e-303 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMGECGDC_00763 4.7e-134 gmuR K UTRA
CMGECGDC_00764 3.5e-41
CMGECGDC_00765 2.4e-267 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMGECGDC_00766 9.5e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMGECGDC_00767 6.8e-156 ypbG 2.7.1.2 GK ROK family
CMGECGDC_00768 1.6e-85 C Nitroreductase family
CMGECGDC_00769 1.3e-108 S Domain of unknown function (DUF4767)
CMGECGDC_00770 8.1e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMGECGDC_00771 6.8e-153 yitS S Uncharacterised protein, DegV family COG1307
CMGECGDC_00772 1.7e-99 3.6.1.27 I Acid phosphatase homologues
CMGECGDC_00773 8.7e-192 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CMGECGDC_00775 4.3e-180 L Belongs to the 'phage' integrase family
CMGECGDC_00776 2.4e-11
CMGECGDC_00777 5.8e-83
CMGECGDC_00779 1.2e-55 ansR 3.4.21.88 K Cro/C1-type HTH DNA-binding domain
CMGECGDC_00780 4.4e-29 2.3.1.19 K Helix-turn-helix XRE-family like proteins
CMGECGDC_00781 8.1e-252 yifK E Amino acid permease
CMGECGDC_00782 6.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CMGECGDC_00783 5.6e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CMGECGDC_00784 0.0 aha1 P E1-E2 ATPase
CMGECGDC_00785 5e-159 metQ1 P Belongs to the nlpA lipoprotein family
CMGECGDC_00786 2.2e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMGECGDC_00787 2.7e-35 metI P ABC transporter permease
CMGECGDC_00788 1.6e-35 metI P ABC transporter permease
CMGECGDC_00789 2.9e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CMGECGDC_00790 2e-266 frdC 1.3.5.4 C FAD binding domain
CMGECGDC_00791 8e-293 M domain protein
CMGECGDC_00792 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CMGECGDC_00793 1.2e-257 pepC 3.4.22.40 E Peptidase C1-like family
CMGECGDC_00794 1.2e-274 P Sodium:sulfate symporter transmembrane region
CMGECGDC_00795 1.1e-155 ydjP I Alpha/beta hydrolase family
CMGECGDC_00796 8.2e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CMGECGDC_00797 4.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
CMGECGDC_00798 1.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
CMGECGDC_00799 9.2e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
CMGECGDC_00800 1.3e-70 yeaL S Protein of unknown function (DUF441)
CMGECGDC_00801 3.3e-13
CMGECGDC_00802 3.8e-148 cbiQ P cobalt transport
CMGECGDC_00803 0.0 ykoD P ABC transporter, ATP-binding protein
CMGECGDC_00804 7.4e-95 S UPF0397 protein
CMGECGDC_00805 1.3e-63 S Domain of unknown function DUF1828
CMGECGDC_00806 2.2e-54
CMGECGDC_00807 1.2e-177 citR K Putative sugar-binding domain
CMGECGDC_00808 5.5e-245 yjjP S Putative threonine/serine exporter
CMGECGDC_00809 1.5e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CMGECGDC_00810 2.1e-174 prmA J Ribosomal protein L11 methyltransferase
CMGECGDC_00811 4e-49
CMGECGDC_00812 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CMGECGDC_00813 1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CMGECGDC_00814 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
CMGECGDC_00815 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CMGECGDC_00816 2.5e-225 patA 2.6.1.1 E Aminotransferase
CMGECGDC_00817 2.8e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CMGECGDC_00818 3.5e-154 S reductase
CMGECGDC_00819 1.6e-151 yxeH S hydrolase
CMGECGDC_00820 3.1e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMGECGDC_00821 3.9e-230 yfnA E Amino Acid
CMGECGDC_00822 2.2e-108 dedA 3.1.3.1 S SNARE associated Golgi protein
CMGECGDC_00823 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CMGECGDC_00824 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CMGECGDC_00825 0.0 I Acyltransferase
CMGECGDC_00826 2.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CMGECGDC_00827 3.6e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CMGECGDC_00828 5.1e-32 yrvD S Lipopolysaccharide assembly protein A domain
CMGECGDC_00829 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CMGECGDC_00830 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CMGECGDC_00832 0.0 dnaE 2.7.7.7 L DNA polymerase
CMGECGDC_00833 7.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CMGECGDC_00834 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CMGECGDC_00835 5e-170 cvfB S S1 domain
CMGECGDC_00836 1.6e-168 xerD D recombinase XerD
CMGECGDC_00837 1.7e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMGECGDC_00838 1.3e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CMGECGDC_00839 3.2e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CMGECGDC_00840 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CMGECGDC_00841 2.2e-117 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CMGECGDC_00842 1.1e-46 M Lysin motif
CMGECGDC_00843 2.4e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CMGECGDC_00844 2.3e-202 rpsA 1.17.7.4 J Ribosomal protein S1
CMGECGDC_00845 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CMGECGDC_00846 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CMGECGDC_00847 2.1e-230 S Tetratricopeptide repeat protein
CMGECGDC_00848 1.3e-162 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMGECGDC_00849 1.1e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CMGECGDC_00850 1.2e-107 hlyIII S protein, hemolysin III
CMGECGDC_00851 2.1e-149 DegV S Uncharacterised protein, DegV family COG1307
CMGECGDC_00852 2.7e-35 yozE S Belongs to the UPF0346 family
CMGECGDC_00853 3.5e-283 yjcE P Sodium proton antiporter
CMGECGDC_00854 1e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CMGECGDC_00855 1.1e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMGECGDC_00856 3.6e-157 dprA LU DNA protecting protein DprA
CMGECGDC_00857 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CMGECGDC_00858 6.1e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CMGECGDC_00859 7.3e-169 xerC D Phage integrase, N-terminal SAM-like domain
CMGECGDC_00860 1.1e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CMGECGDC_00861 1.7e-233 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CMGECGDC_00862 1.8e-180 lacX 5.1.3.3 G Aldose 1-epimerase
CMGECGDC_00863 1.5e-65
CMGECGDC_00864 1.3e-57 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMGECGDC_00865 5e-165 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMGECGDC_00866 3.2e-158 S Alpha/beta hydrolase of unknown function (DUF915)
CMGECGDC_00867 1.4e-150 xerD L Phage integrase, N-terminal SAM-like domain
CMGECGDC_00868 3.5e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMGECGDC_00869 1.1e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMGECGDC_00870 6.9e-275 pepV 3.5.1.18 E dipeptidase PepV
CMGECGDC_00871 5.3e-286 E Amino acid permease
CMGECGDC_00872 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
CMGECGDC_00873 3.2e-247 ynbB 4.4.1.1 P aluminum resistance
CMGECGDC_00874 3.9e-119 ktrA P domain protein
CMGECGDC_00875 4e-240 ktrB P Potassium uptake protein
CMGECGDC_00876 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
CMGECGDC_00877 1.7e-81 C Flavodoxin
CMGECGDC_00878 0.0 uvrA3 L excinuclease ABC, A subunit
CMGECGDC_00879 5.9e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
CMGECGDC_00880 1.8e-113 3.6.1.27 I Acid phosphatase homologues
CMGECGDC_00881 4.5e-67 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMGECGDC_00882 4.3e-208 pbpX1 V Beta-lactamase
CMGECGDC_00883 1.5e-155 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
CMGECGDC_00884 3.1e-93 S ECF-type riboflavin transporter, S component
CMGECGDC_00885 2.1e-216 S Putative peptidoglycan binding domain
CMGECGDC_00886 6.5e-241
CMGECGDC_00887 0.0 treB 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMGECGDC_00888 2.9e-128 treR K UTRA
CMGECGDC_00889 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
CMGECGDC_00890 2.8e-128 M Glycosyl transferases group 1
CMGECGDC_00891 3.8e-99 UW LPXTG-motif cell wall anchor domain protein
CMGECGDC_00892 2.4e-164 M domain protein
CMGECGDC_00893 2.6e-21 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
CMGECGDC_00894 0.0 UW LPXTG-motif cell wall anchor domain protein
CMGECGDC_00895 1.4e-134 K AraC-like ligand binding domain
CMGECGDC_00896 8.5e-260 sacP 2.7.1.211 G phosphotransferase system, EIIB
CMGECGDC_00897 8.7e-239 scrB 2.7.1.211, 3.2.1.26 GH32 G Glycosyl hydrolases family 32
CMGECGDC_00898 0.0 rafA 3.2.1.22 G alpha-galactosidase
CMGECGDC_00899 1.5e-58
CMGECGDC_00900 6.4e-51 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
CMGECGDC_00901 9.5e-34
CMGECGDC_00902 8e-87
CMGECGDC_00903 3e-262 N Uncharacterized conserved protein (DUF2075)
CMGECGDC_00905 1.4e-199 amd 3.5.1.47 E Peptidase family M20/M25/M40
CMGECGDC_00906 2.6e-126 G Peptidase_C39 like family
CMGECGDC_00907 1.3e-180 M NlpC/P60 family
CMGECGDC_00908 0.0 UW LPXTG-motif cell wall anchor domain protein
CMGECGDC_00909 1.7e-124 S Sucrose-6F-phosphate phosphohydrolase
CMGECGDC_00910 5e-143
CMGECGDC_00911 1.6e-253 S C4-dicarboxylate anaerobic carrier
CMGECGDC_00912 4.8e-54 yjaB_1 K Acetyltransferase (GNAT) domain
CMGECGDC_00914 8e-42 C Aldo/keto reductase family
CMGECGDC_00915 2.2e-73 C Aldo/keto reductase family
CMGECGDC_00916 3e-51 1.14.99.57 S Antibiotic biosynthesis monooxygenase
CMGECGDC_00917 2.5e-84 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CMGECGDC_00918 4.6e-224 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
CMGECGDC_00919 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CMGECGDC_00920 1.1e-203 S Uncharacterized protein conserved in bacteria (DUF2252)
CMGECGDC_00921 4.3e-148 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
CMGECGDC_00922 6.8e-113 S Hydrolases of the alpha beta superfamily
CMGECGDC_00923 1.3e-42 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
CMGECGDC_00924 1.3e-33
CMGECGDC_00926 1.6e-194 yniG EGP Major facilitator Superfamily
CMGECGDC_00927 1.2e-52 S Peptidase propeptide and YPEB domain
CMGECGDC_00928 2.6e-53 1.6.5.2 GM NmrA-like family
CMGECGDC_00929 5.1e-49 K helix_turn_helix, mercury resistance
CMGECGDC_00930 8.8e-164 rocF 3.5.3.1, 3.5.3.11 E Arginase family
CMGECGDC_00931 2.1e-114 ylbE GM NAD dependent epimerase dehydratase family protein
CMGECGDC_00932 6.6e-159 K Transcriptional regulator
CMGECGDC_00933 7.7e-168 S Oxidoreductase, aldo keto reductase family protein
CMGECGDC_00934 4.3e-166 akr5f 1.1.1.346 S reductase
CMGECGDC_00935 2.7e-165 yvgN C Aldo keto reductase
CMGECGDC_00936 4.1e-217 S SLAP domain
CMGECGDC_00937 4.1e-103 yyaR K Acetyltransferase (GNAT) domain
CMGECGDC_00940 6.8e-104
CMGECGDC_00941 6.8e-78 K Transcriptional regulator
CMGECGDC_00942 1.9e-245 brnQ U Component of the transport system for branched-chain amino acids
CMGECGDC_00943 3e-164 S reductase
CMGECGDC_00944 1.3e-170
CMGECGDC_00945 4.2e-33 K Transcriptional regulator
CMGECGDC_00946 9.3e-113 papP P ABC transporter, permease protein
CMGECGDC_00947 2.2e-77 P ABC transporter permease
CMGECGDC_00948 3.5e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CMGECGDC_00949 2.2e-159 cjaA ET ABC transporter substrate-binding protein
CMGECGDC_00950 8.3e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CMGECGDC_00951 8.7e-110 5.4.2.11 G Phosphoglycerate mutase family
CMGECGDC_00952 3.4e-174 4.1.1.45 S Amidohydrolase
CMGECGDC_00953 1.1e-29
CMGECGDC_00954 2.5e-109
CMGECGDC_00955 4.9e-108
CMGECGDC_00956 1.3e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
CMGECGDC_00957 2.3e-215 ynfM EGP Major facilitator Superfamily
CMGECGDC_00958 1e-153 K Bacterial regulatory helix-turn-helix protein, lysR family
CMGECGDC_00959 8.2e-119 3.6.1.55 F NUDIX domain
CMGECGDC_00960 1.3e-76
CMGECGDC_00961 3.6e-87 FG HIT domain
CMGECGDC_00962 1.1e-62
CMGECGDC_00963 3.7e-93 rimL J Acetyltransferase (GNAT) domain
CMGECGDC_00964 1.1e-101 S Alpha/beta hydrolase family
CMGECGDC_00965 9.7e-101
CMGECGDC_00966 1.3e-71
CMGECGDC_00967 1.5e-146 2.4.2.3 F Phosphorylase superfamily
CMGECGDC_00968 6.2e-108 5.4.2.11 G Phosphoglycerate mutase family
CMGECGDC_00969 9.4e-112 2.4.2.3 F Phosphorylase superfamily
CMGECGDC_00970 1.4e-144 2.4.2.3 F Phosphorylase superfamily
CMGECGDC_00971 1.4e-112 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CMGECGDC_00972 7.2e-36
CMGECGDC_00973 8.3e-53 mleP S Sodium Bile acid symporter family
CMGECGDC_00974 1.5e-91
CMGECGDC_00975 1.3e-38
CMGECGDC_00976 1.8e-167 mleR K LysR family
CMGECGDC_00977 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
CMGECGDC_00978 1.9e-101 ltrA S Bacterial low temperature requirement A protein (LtrA)
CMGECGDC_00979 4.4e-244 yrvN L AAA C-terminal domain
CMGECGDC_00980 2.9e-195 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CMGECGDC_00981 7.7e-114 S L,D-transpeptidase catalytic domain
CMGECGDC_00982 4.7e-218 2.1.1.14 E methionine synthase, vitamin-B12 independent
CMGECGDC_00983 2.3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CMGECGDC_00984 7.9e-67 L nuclease
CMGECGDC_00985 3.3e-155 F DNA/RNA non-specific endonuclease
CMGECGDC_00986 4.3e-115 ywnB S NAD(P)H-binding
CMGECGDC_00987 1.8e-240 steT E amino acid
CMGECGDC_00988 4.4e-106 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CMGECGDC_00989 2.4e-40 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CMGECGDC_00990 2.2e-148 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CMGECGDC_00991 0.0 ppc 4.1.1.31 C phosphoenolpyruvate carboxylase activity
CMGECGDC_00992 0.0
CMGECGDC_00993 0.0
CMGECGDC_00994 3.5e-174 yobV1 K WYL domain
CMGECGDC_00995 3.1e-83 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
CMGECGDC_00996 2.6e-146 IQ reductase
CMGECGDC_00997 7.1e-55 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
CMGECGDC_00998 7.9e-114 tas C Aldo/keto reductase family
CMGECGDC_00999 2.9e-60 C aldo keto reductase
CMGECGDC_01000 3.6e-146 glcU U ribose uptake protein RbsU
CMGECGDC_01001 1e-20 C Flavodoxin
CMGECGDC_01003 2.7e-98 fldA C Flavodoxin
CMGECGDC_01004 7.7e-100 P esterase
CMGECGDC_01005 2.7e-260 gor 1.8.1.7 C Glutathione reductase
CMGECGDC_01006 4.1e-23
CMGECGDC_01007 4.2e-141 fldA C Flavodoxin
CMGECGDC_01008 7.8e-97 S LexA-binding, inner membrane-associated putative hydrolase
CMGECGDC_01009 2.3e-14 C Flavodoxin
CMGECGDC_01010 2.6e-149 P FAD-binding domain
CMGECGDC_01011 3.3e-77 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
CMGECGDC_01013 3e-251 yagE E amino acid
CMGECGDC_01014 1.3e-12 S Alpha beta hydrolase
CMGECGDC_01015 5e-44 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMGECGDC_01016 9.2e-17 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMGECGDC_01017 2.2e-18 magIII L Base excision DNA repair protein, HhH-GPD family
CMGECGDC_01018 1.9e-168 MA20_14895 S Conserved hypothetical protein 698
CMGECGDC_01019 7e-101
CMGECGDC_01020 1.3e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CMGECGDC_01021 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMGECGDC_01022 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMGECGDC_01023 7.8e-185 K Transcriptional regulator
CMGECGDC_01024 2.3e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
CMGECGDC_01025 1.7e-113 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CMGECGDC_01026 1.1e-127 yoaK S Protein of unknown function (DUF1275)
CMGECGDC_01027 8.2e-66 fic D Fic/DOC family
CMGECGDC_01029 1.5e-286 V ABC-type multidrug transport system, ATPase and permease components
CMGECGDC_01030 2.3e-287 V ABC-type multidrug transport system, ATPase and permease components
CMGECGDC_01031 1e-213 EGP Transmembrane secretion effector
CMGECGDC_01032 3.9e-84 K transcriptional
CMGECGDC_01033 3.3e-58 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CMGECGDC_01035 4.3e-200 M Glycosyl hydrolases family 25
CMGECGDC_01036 2.4e-107 XK27_00160 S Domain of unknown function (DUF5052)
CMGECGDC_01037 1.5e-91 adk 2.7.4.3 F topology modulation protein
CMGECGDC_01038 3.1e-59
CMGECGDC_01039 8.4e-196 xerS L Belongs to the 'phage' integrase family
CMGECGDC_01040 6.1e-160 degV S EDD domain protein, DegV family
CMGECGDC_01041 9e-66
CMGECGDC_01042 0.0 FbpA K Fibronectin-binding protein
CMGECGDC_01043 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
CMGECGDC_01044 3e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CMGECGDC_01045 3.2e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMGECGDC_01046 1.1e-86 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CMGECGDC_01047 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CMGECGDC_01048 7.2e-244 cpdA S Calcineurin-like phosphoesterase
CMGECGDC_01049 1.8e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CMGECGDC_01050 6.7e-69 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CMGECGDC_01051 9.4e-106 ypsA S Belongs to the UPF0398 family
CMGECGDC_01052 7.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CMGECGDC_01053 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
CMGECGDC_01054 1.5e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CMGECGDC_01055 5.7e-115 dnaD L DnaD domain protein
CMGECGDC_01056 2.4e-253 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
CMGECGDC_01057 1.4e-89 ypmB S Protein conserved in bacteria
CMGECGDC_01058 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CMGECGDC_01059 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CMGECGDC_01060 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CMGECGDC_01061 6.6e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
CMGECGDC_01062 4.1e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CMGECGDC_01063 9.3e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
CMGECGDC_01064 4.2e-189 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CMGECGDC_01065 5.2e-145 K SIS domain
CMGECGDC_01066 1.3e-107 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
CMGECGDC_01067 4.4e-55 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
CMGECGDC_01068 4.6e-216 iscS 2.8.1.7 E Aminotransferase class V
CMGECGDC_01069 1.1e-267 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
CMGECGDC_01070 3.8e-179
CMGECGDC_01071 4.1e-141
CMGECGDC_01072 8.9e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CMGECGDC_01073 2.2e-27
CMGECGDC_01074 6.8e-131
CMGECGDC_01075 4e-145
CMGECGDC_01076 3.9e-132
CMGECGDC_01077 1.1e-122 skfE V ATPases associated with a variety of cellular activities
CMGECGDC_01078 8e-61 yvoA_1 K Transcriptional regulator, GntR family
CMGECGDC_01079 1.3e-245 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CMGECGDC_01080 7.7e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CMGECGDC_01081 1.3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
CMGECGDC_01082 5.6e-82 mutT 3.6.1.55 F NUDIX domain
CMGECGDC_01083 1.1e-126 S Peptidase family M23
CMGECGDC_01084 1.4e-198 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CMGECGDC_01085 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CMGECGDC_01086 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CMGECGDC_01087 2.3e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CMGECGDC_01088 1.7e-134 recO L Involved in DNA repair and RecF pathway recombination
CMGECGDC_01089 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CMGECGDC_01090 7.9e-99 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CMGECGDC_01091 3.6e-157 phoH T phosphate starvation-inducible protein PhoH
CMGECGDC_01092 6.5e-70 yqeY S YqeY-like protein
CMGECGDC_01093 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CMGECGDC_01094 8.9e-153 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CMGECGDC_01095 1.3e-95 S Peptidase family M23
CMGECGDC_01096 2.8e-110 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMGECGDC_01097 2.2e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMGECGDC_01098 4.8e-122
CMGECGDC_01099 4.8e-162 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CMGECGDC_01100 1.3e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CMGECGDC_01101 6.4e-287 thrC 4.2.3.1 E Threonine synthase
CMGECGDC_01102 9.4e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
CMGECGDC_01103 0.0 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
CMGECGDC_01104 1.1e-18 yjgN S Bacterial protein of unknown function (DUF898)
CMGECGDC_01105 2.8e-103 lacA 2.3.1.79 S Transferase hexapeptide repeat
CMGECGDC_01106 0.0
CMGECGDC_01107 2e-10
CMGECGDC_01108 4.5e-252 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
CMGECGDC_01109 6.4e-201 brnQ U Component of the transport system for branched-chain amino acids
CMGECGDC_01110 1.3e-295
CMGECGDC_01111 1.1e-121 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
CMGECGDC_01112 1.3e-99
CMGECGDC_01113 2.2e-108 K LysR substrate binding domain
CMGECGDC_01114 3.7e-15
CMGECGDC_01115 4.8e-229 S Sterol carrier protein domain
CMGECGDC_01116 4.8e-99 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
CMGECGDC_01117 1.5e-155 lysR5 K LysR substrate binding domain
CMGECGDC_01118 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
CMGECGDC_01119 1.8e-87 3.4.21.96 S SLAP domain
CMGECGDC_01120 3.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMGECGDC_01121 4.6e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
CMGECGDC_01122 1.6e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CMGECGDC_01123 1.1e-211 S Bacterial protein of unknown function (DUF871)
CMGECGDC_01124 4.7e-151 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
CMGECGDC_01126 2.9e-78 K Acetyltransferase (GNAT) domain
CMGECGDC_01127 3.7e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CMGECGDC_01128 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CMGECGDC_01129 4.8e-120 srtA 3.4.22.70 M sortase family
CMGECGDC_01130 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CMGECGDC_01131 7.8e-200 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CMGECGDC_01132 0.0 dnaK O Heat shock 70 kDa protein
CMGECGDC_01133 1.9e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CMGECGDC_01134 1.7e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CMGECGDC_01135 5.7e-283 lsa S ABC transporter
CMGECGDC_01136 5.2e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CMGECGDC_01137 1e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CMGECGDC_01138 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CMGECGDC_01139 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CMGECGDC_01140 8.4e-48 rplGA J ribosomal protein
CMGECGDC_01141 1.4e-47 ylxR K Protein of unknown function (DUF448)
CMGECGDC_01142 3.3e-198 nusA K Participates in both transcription termination and antitermination
CMGECGDC_01143 7.2e-83 rimP J Required for maturation of 30S ribosomal subunits
CMGECGDC_01144 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMGECGDC_01145 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CMGECGDC_01146 2.6e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CMGECGDC_01147 1.7e-145 cdsA 2.7.7.41 I Belongs to the CDS family
CMGECGDC_01148 9.3e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CMGECGDC_01149 8.7e-88 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CMGECGDC_01150 2.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CMGECGDC_01151 2.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CMGECGDC_01152 1.1e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
CMGECGDC_01153 2.5e-197 yabB 2.1.1.223 L Methyltransferase small domain
CMGECGDC_01154 6.4e-116 plsC 2.3.1.51 I Acyltransferase
CMGECGDC_01155 1e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
CMGECGDC_01156 0.0 pepO 3.4.24.71 O Peptidase family M13
CMGECGDC_01157 3e-86 mdlB V ABC transporter
CMGECGDC_01158 1.2e-187 mdlB V ABC transporter
CMGECGDC_01159 0.0 mdlA V ABC transporter
CMGECGDC_01160 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
CMGECGDC_01161 1.1e-37 ynzC S UPF0291 protein
CMGECGDC_01162 1.5e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CMGECGDC_01163 3.1e-144 E GDSL-like Lipase/Acylhydrolase family
CMGECGDC_01164 3.7e-122 ung2 3.2.2.27 L Uracil-DNA glycosylase
CMGECGDC_01165 3.4e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
CMGECGDC_01166 0.0 S Bacterial membrane protein, YfhO
CMGECGDC_01167 3.7e-70 2.4.1.83 GT2 S GtrA-like protein
CMGECGDC_01168 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CMGECGDC_01169 5e-128 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CMGECGDC_01170 4.7e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CMGECGDC_01171 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CMGECGDC_01172 2.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CMGECGDC_01173 1.6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CMGECGDC_01174 3.2e-259 yfnA E amino acid
CMGECGDC_01175 2.8e-67
CMGECGDC_01176 2.5e-288 pipD E Dipeptidase
CMGECGDC_01177 2.1e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CMGECGDC_01178 0.0 smc D Required for chromosome condensation and partitioning
CMGECGDC_01179 3.8e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CMGECGDC_01180 9.4e-278 lacS G Transporter
CMGECGDC_01181 7.6e-35 lacS G Transporter
CMGECGDC_01182 0.0 lacZ 3.2.1.23 G -beta-galactosidase
CMGECGDC_01183 8.8e-113
CMGECGDC_01184 2.3e-187 M domain protein
CMGECGDC_01185 2.3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CMGECGDC_01186 4.3e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CMGECGDC_01187 1.2e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CMGECGDC_01188 1.8e-167 S SLAP domain
CMGECGDC_01189 1.1e-39 C FMN binding
CMGECGDC_01191 1.2e-45
CMGECGDC_01192 5.3e-52 S Domain of unknown function (DUF4160)
CMGECGDC_01193 1.1e-96 S Domain of unknown function (DUF4811)
CMGECGDC_01194 1.6e-266 lmrB EGP Major facilitator Superfamily
CMGECGDC_01195 5e-75 merR K MerR HTH family regulatory protein
CMGECGDC_01196 3.7e-159 msmR K helix_turn_helix, arabinose operon control protein
CMGECGDC_01197 4e-242 msmE G Bacterial extracellular solute-binding protein
CMGECGDC_01198 1.8e-156 msmF P Binding-protein-dependent transport system inner membrane component
CMGECGDC_01199 1.5e-152 msmG P Binding-protein-dependent transport system inner membrane component
CMGECGDC_01200 2.3e-209 msmX P Belongs to the ABC transporter superfamily
CMGECGDC_01201 0.0 rafA 3.2.1.22 G alpha-galactosidase
CMGECGDC_01202 1.6e-282 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
CMGECGDC_01203 5.6e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
CMGECGDC_01204 2.1e-61 dhaM 2.7.1.121 S PTS system fructose IIA component
CMGECGDC_01205 1.2e-103 dhaL 2.7.1.121 S Dak2
CMGECGDC_01206 3.3e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
CMGECGDC_01207 1.7e-113 2.7.6.5 T Region found in RelA / SpoT proteins
CMGECGDC_01208 1.5e-118 K response regulator
CMGECGDC_01209 1.2e-233 sptS 2.7.13.3 T Histidine kinase
CMGECGDC_01210 1.8e-212 EGP Major facilitator Superfamily
CMGECGDC_01211 9.2e-71 O OsmC-like protein
CMGECGDC_01212 9e-127 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
CMGECGDC_01213 2.4e-128
CMGECGDC_01215 2.4e-127 S Alpha beta hydrolase
CMGECGDC_01216 1.1e-278 yjeM E Amino Acid
CMGECGDC_01217 2.9e-13
CMGECGDC_01218 4e-109 pncA Q Isochorismatase family
CMGECGDC_01219 6e-27 C pentaerythritol trinitrate reductase activity
CMGECGDC_01220 9.3e-214 L TIGRFAM transposase, IS605 OrfB family
CMGECGDC_01221 8.1e-09 L Probable transposase
CMGECGDC_01222 5.7e-177 C Oxidoreductase
CMGECGDC_01223 1e-90
CMGECGDC_01224 1.5e-244 pgaC GT2 M Glycosyl transferase
CMGECGDC_01225 3.6e-143 T EAL domain
CMGECGDC_01226 1e-130 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
CMGECGDC_01227 2e-208 2.7.7.65 T GGDEF domain
CMGECGDC_01230 0.0 1.3.5.4 C FMN_bind
CMGECGDC_01231 3.4e-160 K Bacterial regulatory helix-turn-helix protein, lysR family
CMGECGDC_01233 1.1e-118 S GyrI-like small molecule binding domain
CMGECGDC_01234 2.6e-64 S ASCH domain
CMGECGDC_01235 1.7e-57 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
CMGECGDC_01236 1.2e-32 ylbE GM NAD(P)H-binding
CMGECGDC_01237 1.2e-64 ylbE GM NAD(P)H-binding
CMGECGDC_01238 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
CMGECGDC_01239 3.9e-62 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
CMGECGDC_01240 9.1e-264 npr 1.11.1.1 C NADH oxidase
CMGECGDC_01242 0.0 oppA E ABC transporter substrate-binding protein
CMGECGDC_01243 5.7e-52 S Iron-sulfur cluster assembly protein
CMGECGDC_01244 9e-156 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
CMGECGDC_01245 8.1e-125 sdaAB 4.3.1.17 E Serine dehydratase beta chain
CMGECGDC_01246 8.8e-47
CMGECGDC_01247 1.5e-147 metQ2 P Belongs to the nlpA lipoprotein family
CMGECGDC_01248 1e-50
CMGECGDC_01249 8.8e-95 wecD K acetyltransferase
CMGECGDC_01250 0.0 UW LPXTG-motif cell wall anchor domain protein
CMGECGDC_01251 5.2e-103 O Matrixin
CMGECGDC_01252 1.8e-248 clcA P chloride
CMGECGDC_01253 0.0 3.6.3.8 P P-type ATPase
CMGECGDC_01254 1.2e-117 GM NmrA-like family
CMGECGDC_01255 6.4e-119 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CMGECGDC_01256 1.5e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CMGECGDC_01257 9.8e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CMGECGDC_01258 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMGECGDC_01259 8.5e-184 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CMGECGDC_01260 6.1e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CMGECGDC_01261 7.1e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CMGECGDC_01262 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
CMGECGDC_01264 0.0
CMGECGDC_01265 6.6e-151 glcU U sugar transport
CMGECGDC_01266 4.9e-47
CMGECGDC_01267 8.1e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
CMGECGDC_01268 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CMGECGDC_01269 2.3e-47 S Motility quorum-sensing regulator, toxin of MqsA
CMGECGDC_01270 4.2e-65 ps301 K sequence-specific DNA binding
CMGECGDC_01271 3.4e-16
CMGECGDC_01272 6.4e-100 S Bacterial PH domain
CMGECGDC_01273 1.8e-237 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMGECGDC_01274 7.3e-206 xylR GK ROK family
CMGECGDC_01275 1.1e-166 bglK 2.7.1.2, 2.7.1.85 GK ROK family
CMGECGDC_01276 7.7e-309 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMGECGDC_01277 0.0 yic1 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
CMGECGDC_01278 0.0 lacA 3.2.1.23 G -beta-galactosidase
CMGECGDC_01279 6.8e-252
CMGECGDC_01280 1.5e-152 S haloacid dehalogenase-like hydrolase
CMGECGDC_01281 8.5e-290 V ABC-type multidrug transport system, ATPase and permease components
CMGECGDC_01282 5.2e-295 V ABC-type multidrug transport system, ATPase and permease components
CMGECGDC_01283 1e-65 arsC 1.20.4.1 P Belongs to the ArsC family
CMGECGDC_01284 6.5e-178 I Carboxylesterase family
CMGECGDC_01285 1.7e-165 S Membrane
CMGECGDC_01287 2e-185 M Glycosyl hydrolases family 25
CMGECGDC_01288 3.6e-154 cinI S Serine hydrolase (FSH1)
CMGECGDC_01289 5e-311 S Predicted membrane protein (DUF2207)
CMGECGDC_01290 3.7e-153 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
CMGECGDC_01291 9.2e-98 E ABC transporter
CMGECGDC_01292 6.7e-60 oppA E ABC transporter
CMGECGDC_01294 3.2e-109 Q Imidazolonepropionase and related amidohydrolases
CMGECGDC_01295 1.3e-105 Q Imidazolonepropionase and related amidohydrolases
CMGECGDC_01296 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CMGECGDC_01297 1.8e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CMGECGDC_01298 8.3e-257 S Uncharacterized protein conserved in bacteria (DUF2325)
CMGECGDC_01299 2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMGECGDC_01300 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
CMGECGDC_01301 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CMGECGDC_01302 3.2e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CMGECGDC_01303 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMGECGDC_01304 6.8e-72 yqhY S Asp23 family, cell envelope-related function
CMGECGDC_01305 3.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CMGECGDC_01306 1.9e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMGECGDC_01307 7.3e-213 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMGECGDC_01308 3.4e-36 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMGECGDC_01309 6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CMGECGDC_01310 3.5e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CMGECGDC_01311 4.7e-310 recN L May be involved in recombinational repair of damaged DNA
CMGECGDC_01312 1.8e-80 6.3.3.2 S ASCH
CMGECGDC_01313 1.5e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
CMGECGDC_01314 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CMGECGDC_01315 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CMGECGDC_01316 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMGECGDC_01317 1.3e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CMGECGDC_01318 2.3e-139 stp 3.1.3.16 T phosphatase
CMGECGDC_01319 0.0 KLT serine threonine protein kinase
CMGECGDC_01320 8e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CMGECGDC_01321 4.5e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CMGECGDC_01322 6.9e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
CMGECGDC_01323 4.2e-52
CMGECGDC_01324 3.7e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CMGECGDC_01325 6.8e-57 asp S Asp23 family, cell envelope-related function
CMGECGDC_01326 5.2e-306 yloV S DAK2 domain fusion protein YloV
CMGECGDC_01327 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CMGECGDC_01328 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CMGECGDC_01329 5.7e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMGECGDC_01330 2.5e-197 oppD P Belongs to the ABC transporter superfamily
CMGECGDC_01331 6.1e-177 oppF P Belongs to the ABC transporter superfamily
CMGECGDC_01332 2.3e-176 oppB P ABC transporter permease
CMGECGDC_01333 2.9e-144 oppC P Binding-protein-dependent transport system inner membrane component
CMGECGDC_01334 0.0 oppA E ABC transporter substrate-binding protein
CMGECGDC_01335 0.0 oppA E ABC transporter substrate-binding protein
CMGECGDC_01336 6.6e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CMGECGDC_01337 0.0 clpE O AAA domain (Cdc48 subfamily)
CMGECGDC_01338 5.1e-170 S Alpha/beta hydrolase of unknown function (DUF915)
CMGECGDC_01339 1.4e-229 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMGECGDC_01340 5e-125 XK27_06785 V ABC transporter, ATP-binding protein
CMGECGDC_01341 0.0 XK27_06780 V ABC transporter permease
CMGECGDC_01342 9.6e-36
CMGECGDC_01343 7.4e-289 ytgP S Polysaccharide biosynthesis protein
CMGECGDC_01344 4.3e-167 lysA2 M Glycosyl hydrolases family 25
CMGECGDC_01345 4.4e-126 S Protein of unknown function (DUF975)
CMGECGDC_01346 2.7e-61
CMGECGDC_01347 2e-177 pbpX2 V Beta-lactamase
CMGECGDC_01348 1.1e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CMGECGDC_01349 7.4e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMGECGDC_01350 2.6e-241 dltB M MBOAT, membrane-bound O-acyltransferase family
CMGECGDC_01351 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMGECGDC_01352 7.6e-18 S D-Ala-teichoic acid biosynthesis protein
CMGECGDC_01353 3.6e-40
CMGECGDC_01354 9.1e-217 ywhK S Membrane
CMGECGDC_01355 2.1e-82 ykuL S (CBS) domain
CMGECGDC_01356 0.0 cadA P P-type ATPase
CMGECGDC_01357 5e-194 napA P Sodium/hydrogen exchanger family
CMGECGDC_01358 3.5e-72 S Putative adhesin
CMGECGDC_01359 4.3e-286 V ABC transporter transmembrane region
CMGECGDC_01360 2.8e-154 mutR K Helix-turn-helix XRE-family like proteins
CMGECGDC_01361 3.6e-96 M CHAP domain
CMGECGDC_01362 1.5e-68 K Helix-turn-helix XRE-family like proteins
CMGECGDC_01363 2.7e-120 S CAAX protease self-immunity
CMGECGDC_01364 1.8e-193 S DUF218 domain
CMGECGDC_01365 0.0 macB_3 V ABC transporter, ATP-binding protein
CMGECGDC_01366 1.6e-103 S ECF transporter, substrate-specific component
CMGECGDC_01367 5.6e-186 tcsA S ABC transporter substrate-binding protein PnrA-like
CMGECGDC_01368 5.6e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
CMGECGDC_01369 1.7e-287 xylG 3.6.3.17 S ABC transporter
CMGECGDC_01370 5.1e-207 yufP S Belongs to the binding-protein-dependent transport system permease family
CMGECGDC_01371 2.4e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
CMGECGDC_01372 1.7e-159 yeaE S Aldo/keto reductase family
CMGECGDC_01373 2.5e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CMGECGDC_01374 4.7e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
CMGECGDC_01375 1.4e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
CMGECGDC_01376 8.5e-145 cof S haloacid dehalogenase-like hydrolase
CMGECGDC_01377 1.1e-231 pbuG S permease
CMGECGDC_01378 1e-273 E amino acid
CMGECGDC_01379 1.8e-153 xth 3.1.11.2 L exodeoxyribonuclease III
CMGECGDC_01380 1.4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMGECGDC_01381 2.8e-15 S endonuclease exonuclease phosphatase family protein
CMGECGDC_01382 2.7e-134 S endonuclease exonuclease phosphatase family protein
CMGECGDC_01383 6.5e-30 S endonuclease exonuclease phosphatase family protein
CMGECGDC_01384 1.3e-151 3.1.3.102, 3.1.3.104 S hydrolase
CMGECGDC_01385 0.0 tetP J elongation factor G
CMGECGDC_01386 4e-138 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CMGECGDC_01387 1.5e-178 ABC-SBP S ABC transporter
CMGECGDC_01388 2.6e-126 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
CMGECGDC_01389 2.6e-135 XK27_08845 S ABC transporter, ATP-binding protein
CMGECGDC_01390 1.7e-52
CMGECGDC_01391 7.6e-247 G Major Facilitator
CMGECGDC_01392 5.5e-15
CMGECGDC_01393 3.6e-105 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
CMGECGDC_01394 7.1e-176 K AI-2E family transporter
CMGECGDC_01395 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
CMGECGDC_01396 2.4e-55 S Domain of unknown function (DUF4430)
CMGECGDC_01397 4.5e-86 S ECF transporter, substrate-specific component
CMGECGDC_01398 2.5e-98 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
CMGECGDC_01399 3.6e-151 S Putative ABC-transporter type IV
CMGECGDC_01400 1.3e-230 S LPXTG cell wall anchor motif
CMGECGDC_01401 2.3e-278 pipD E Dipeptidase
CMGECGDC_01402 3.9e-161 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
CMGECGDC_01405 5.3e-20 S Protein of unknown function (DUF3923)
CMGECGDC_01406 6.5e-69 doc S Fic/DOC family
CMGECGDC_01407 1.3e-31
CMGECGDC_01408 4e-234 L Belongs to the 'phage' integrase family
CMGECGDC_01409 1.5e-31
CMGECGDC_01410 4.9e-184 repB EP Plasmid replication protein
CMGECGDC_01411 8.6e-93
CMGECGDC_01412 1.1e-206 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CMGECGDC_01413 4.6e-54
CMGECGDC_01414 1.4e-183
CMGECGDC_01415 1.6e-58 cadX K helix_turn_helix, Arsenical Resistance Operon Repressor
CMGECGDC_01416 6.7e-97 cadD P Cadmium resistance transporter
CMGECGDC_01418 2.6e-238 I Protein of unknown function (DUF2974)
CMGECGDC_01419 1e-30
CMGECGDC_01420 1e-16 S CsbD-like
CMGECGDC_01421 1.6e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
CMGECGDC_01422 8.3e-176 degV S DegV family
CMGECGDC_01423 1.1e-172 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
CMGECGDC_01424 5.5e-256 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CMGECGDC_01425 2.1e-71 rplI J Binds to the 23S rRNA
CMGECGDC_01426 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CMGECGDC_01427 8.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CMGECGDC_01428 2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CMGECGDC_01429 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
CMGECGDC_01430 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMGECGDC_01431 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMGECGDC_01432 1.3e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CMGECGDC_01433 5.9e-35 yaaA S S4 domain protein YaaA
CMGECGDC_01434 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CMGECGDC_01435 1.3e-246 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CMGECGDC_01436 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
CMGECGDC_01437 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CMGECGDC_01438 5.1e-151 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMGECGDC_01439 3.9e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CMGECGDC_01440 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CMGECGDC_01441 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
CMGECGDC_01442 5.8e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CMGECGDC_01443 1.1e-281 clcA P chloride
CMGECGDC_01444 1.7e-212
CMGECGDC_01445 1.5e-18
CMGECGDC_01446 5.5e-118 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
CMGECGDC_01447 2.4e-130 WQ51_05710 S Mitochondrial biogenesis AIM24
CMGECGDC_01448 2.7e-175 XK27_05540 S DUF218 domain
CMGECGDC_01449 0.0 copA 3.6.3.54 P P-type ATPase
CMGECGDC_01450 3.7e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CMGECGDC_01451 1.8e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CMGECGDC_01452 3.9e-75 atkY K Penicillinase repressor
CMGECGDC_01453 3.8e-309 E ABC transporter, substratebinding protein
CMGECGDC_01454 1.2e-23
CMGECGDC_01455 3.4e-223 pbuG S permease
CMGECGDC_01456 0.0 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
CMGECGDC_01457 5.6e-177 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
CMGECGDC_01458 5e-227 pbuG S permease
CMGECGDC_01459 5.1e-128 K helix_turn_helix, mercury resistance
CMGECGDC_01460 7e-110
CMGECGDC_01462 5.1e-109 S CAAX protease self-immunity
CMGECGDC_01463 1.2e-216 S CAAX protease self-immunity
CMGECGDC_01464 1.4e-37 S Enterocin A Immunity
CMGECGDC_01465 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
CMGECGDC_01466 1.1e-26
CMGECGDC_01467 1.5e-33
CMGECGDC_01468 4e-53 S Enterocin A Immunity
CMGECGDC_01469 9.4e-49 S Enterocin A Immunity
CMGECGDC_01470 7.2e-146 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
CMGECGDC_01471 2.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CMGECGDC_01472 5.8e-195 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
CMGECGDC_01473 2.5e-121 K response regulator
CMGECGDC_01474 0.0 V ABC transporter
CMGECGDC_01475 3.3e-303 V ABC transporter, ATP-binding protein
CMGECGDC_01476 2e-138 XK27_01040 S Protein of unknown function (DUF1129)
CMGECGDC_01477 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CMGECGDC_01478 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
CMGECGDC_01479 3.4e-155 spo0J K Belongs to the ParB family
CMGECGDC_01480 1.3e-137 soj D Sporulation initiation inhibitor
CMGECGDC_01481 7.2e-147 noc K Belongs to the ParB family
CMGECGDC_01482 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
CMGECGDC_01483 7.9e-54 cvpA S Colicin V production protein
CMGECGDC_01484 3.5e-182 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMGECGDC_01485 2.5e-149 3.1.3.48 T Tyrosine phosphatase family
CMGECGDC_01486 3.1e-98 azr 1.5.1.36 S NADPH-dependent FMN reductase
CMGECGDC_01487 7.6e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
CMGECGDC_01488 1.3e-111 K WHG domain
CMGECGDC_01489 1.5e-36
CMGECGDC_01490 1.1e-277 pipD E Dipeptidase
CMGECGDC_01491 9.8e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
CMGECGDC_01492 3.7e-180 hrtB V ABC transporter permease
CMGECGDC_01493 4.8e-96 ygfC K Bacterial regulatory proteins, tetR family
CMGECGDC_01494 2.4e-112 3.1.3.73 G phosphoglycerate mutase
CMGECGDC_01495 2e-140 aroD S Alpha/beta hydrolase family
CMGECGDC_01496 2e-143 S Belongs to the UPF0246 family
CMGECGDC_01497 3.8e-119
CMGECGDC_01498 4.6e-159 2.7.7.12 C Domain of unknown function (DUF4931)
CMGECGDC_01499 9.3e-220 S Putative peptidoglycan binding domain
CMGECGDC_01500 2.6e-26
CMGECGDC_01501 1.3e-252 dtpT U amino acid peptide transporter
CMGECGDC_01502 0.0 pepN 3.4.11.2 E aminopeptidase
CMGECGDC_01503 4.5e-61 lysM M LysM domain
CMGECGDC_01504 4.7e-177
CMGECGDC_01505 2.8e-102 mdtG EGP Major Facilitator Superfamily
CMGECGDC_01506 2.9e-114 mdtG EGP Major facilitator Superfamily
CMGECGDC_01508 6e-213 I transferase activity, transferring acyl groups other than amino-acyl groups
CMGECGDC_01509 1.2e-91 ymdB S Macro domain protein
CMGECGDC_01510 0.0 nisT V ABC transporter
CMGECGDC_01511 3.7e-07
CMGECGDC_01513 1.6e-146 K Helix-turn-helix XRE-family like proteins
CMGECGDC_01514 6.7e-84
CMGECGDC_01515 1.4e-148 malG P ABC transporter permease
CMGECGDC_01516 7.9e-252 malF P Binding-protein-dependent transport system inner membrane component
CMGECGDC_01517 5.9e-214 malE G Bacterial extracellular solute-binding protein
CMGECGDC_01518 1.6e-210 msmX P Belongs to the ABC transporter superfamily
CMGECGDC_01522 2.4e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CMGECGDC_01523 2.9e-260 qacA EGP Major facilitator Superfamily
CMGECGDC_01524 1.5e-30 cydA 1.10.3.14 C ubiquinol oxidase
CMGECGDC_01525 2.3e-116 ndh 1.6.99.3 C NADH dehydrogenase
CMGECGDC_01526 4.4e-91 ndh 1.6.99.3 C NADH dehydrogenase
CMGECGDC_01527 3.9e-119 3.6.1.27 I Acid phosphatase homologues
CMGECGDC_01528 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMGECGDC_01529 2.2e-296 ytgP S Polysaccharide biosynthesis protein
CMGECGDC_01530 4.8e-16
CMGECGDC_01531 5.5e-71 K transcriptional regulator
CMGECGDC_01532 2.8e-17 K transcriptional regulator
CMGECGDC_01533 0.0 sprD D Domain of Unknown Function (DUF1542)
CMGECGDC_01534 3.8e-80 yphH S Cupin domain
CMGECGDC_01535 0.0 S domain, Protein
CMGECGDC_01536 9.1e-40 S Enterocin A Immunity
CMGECGDC_01537 7e-258 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
CMGECGDC_01538 3e-54 yvlA
CMGECGDC_01539 5.5e-197 V Beta-lactamase
CMGECGDC_01540 6.4e-54 pspC KT PspC domain
CMGECGDC_01542 1.7e-243 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CMGECGDC_01543 2.4e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CMGECGDC_01544 6.9e-127 M ErfK YbiS YcfS YnhG
CMGECGDC_01545 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
CMGECGDC_01546 2.3e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
CMGECGDC_01547 4.1e-192 5.3.3.2 C FMN-dependent dehydrogenase
CMGECGDC_01548 6.8e-119
CMGECGDC_01549 1e-43 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
CMGECGDC_01550 2.5e-52 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
CMGECGDC_01551 2.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMGECGDC_01552 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CMGECGDC_01553 6.8e-54 yheA S Belongs to the UPF0342 family
CMGECGDC_01554 2.4e-231 yhaO L Ser Thr phosphatase family protein
CMGECGDC_01555 0.0 L AAA domain
CMGECGDC_01556 8.4e-187 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
CMGECGDC_01557 1.1e-148 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CMGECGDC_01558 1.4e-56
CMGECGDC_01559 2.8e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
CMGECGDC_01560 2e-135 ecsA V ABC transporter, ATP-binding protein
CMGECGDC_01561 7.4e-201 ecsB U ABC transporter
CMGECGDC_01562 1.5e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CMGECGDC_01563 1.1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CMGECGDC_01564 7.4e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMGECGDC_01565 4.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CMGECGDC_01566 0.0
CMGECGDC_01567 1.7e-148 ybbH K Helix-turn-helix domain, rpiR family
CMGECGDC_01568 1.2e-29 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CMGECGDC_01569 5.5e-295 G phosphotransferase system
CMGECGDC_01570 3.1e-294 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMGECGDC_01571 1.8e-92 S Membrane
CMGECGDC_01572 6.6e-167 rocF 3.5.3.1, 3.5.3.11 E Arginase family
CMGECGDC_01573 2.9e-238 mepA V MATE efflux family protein
CMGECGDC_01574 9e-98 L Putative transposase DNA-binding domain
CMGECGDC_01575 1.9e-112 L Putative transposase DNA-binding domain
CMGECGDC_01576 3.2e-178 S SLAP domain
CMGECGDC_01577 7.9e-293 M Peptidase family M1 domain
CMGECGDC_01578 2.4e-194 S Bacteriocin helveticin-J
CMGECGDC_01579 1.1e-50 L RelB antitoxin
CMGECGDC_01580 9.7e-142 qmcA O prohibitin homologues
CMGECGDC_01581 1.1e-124 darA C Flavodoxin
CMGECGDC_01582 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CMGECGDC_01583 9.6e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CMGECGDC_01584 3.6e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CMGECGDC_01585 2.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CMGECGDC_01586 7.6e-39 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMGECGDC_01587 6.1e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMGECGDC_01588 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMGECGDC_01589 1.5e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CMGECGDC_01590 2e-199 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CMGECGDC_01591 2.7e-111 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CMGECGDC_01592 5e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CMGECGDC_01593 5.3e-250 purD 6.3.4.13 F Belongs to the GARS family
CMGECGDC_01594 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMGECGDC_01595 4.8e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CMGECGDC_01596 6.9e-107 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CMGECGDC_01597 2.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CMGECGDC_01598 1.7e-251 dnaB L Replication initiation and membrane attachment
CMGECGDC_01599 6.9e-167 dnaI L Primosomal protein DnaI
CMGECGDC_01600 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CMGECGDC_01601 5.6e-74 K LytTr DNA-binding domain
CMGECGDC_01602 5.7e-71 S Protein of unknown function (DUF3021)
CMGECGDC_01603 3.2e-92
CMGECGDC_01604 3.7e-73 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CMGECGDC_01605 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CMGECGDC_01606 1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CMGECGDC_01607 3.5e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CMGECGDC_01608 1.9e-198 tnpB L Putative transposase DNA-binding domain
CMGECGDC_01609 1.6e-93 yqeG S HAD phosphatase, family IIIA
CMGECGDC_01610 1e-212 yqeH S Ribosome biogenesis GTPase YqeH
CMGECGDC_01611 5.2e-124 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CMGECGDC_01612 1.4e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
CMGECGDC_01613 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CMGECGDC_01614 2.7e-216 ylbM S Belongs to the UPF0348 family
CMGECGDC_01615 2.4e-98 yceD S Uncharacterized ACR, COG1399
CMGECGDC_01616 2.5e-127 K response regulator
CMGECGDC_01617 1.9e-249 arlS 2.7.13.3 T Histidine kinase
CMGECGDC_01618 4.3e-159 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMGECGDC_01619 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CMGECGDC_01620 1.9e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMGECGDC_01621 4.7e-63 yodB K Transcriptional regulator, HxlR family
CMGECGDC_01622 1.2e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CMGECGDC_01623 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMGECGDC_01624 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMGECGDC_01625 6.7e-170 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
CMGECGDC_01626 3.6e-254 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CMGECGDC_01627 1.1e-12 ltrA S Bacterial low temperature requirement A protein (LtrA)
CMGECGDC_01628 1.7e-35 ltrA S Bacterial low temperature requirement A protein (LtrA)
CMGECGDC_01629 0.0 O Belongs to the peptidase S8 family
CMGECGDC_01630 2.3e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
CMGECGDC_01631 0.0 S membrane
CMGECGDC_01632 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
CMGECGDC_01633 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CMGECGDC_01634 1.1e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CMGECGDC_01635 1.2e-118 gluP 3.4.21.105 S Rhomboid family
CMGECGDC_01636 1.6e-32 yqgQ S Bacterial protein of unknown function (DUF910)
CMGECGDC_01637 3.3e-65 yqhL P Rhodanese-like protein
CMGECGDC_01638 2.1e-171 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMGECGDC_01639 1.9e-239 ynbB 4.4.1.1 P aluminum resistance
CMGECGDC_01640 8.9e-264 glnA 6.3.1.2 E glutamine synthetase
CMGECGDC_01641 5.5e-133 ybbM S Uncharacterised protein family (UPF0014)
CMGECGDC_01642 1.8e-116 ybbL S ABC transporter, ATP-binding protein
CMGECGDC_01643 4e-167
CMGECGDC_01644 4.1e-152
CMGECGDC_01647 1.9e-248 lmrB EGP Major facilitator Superfamily
CMGECGDC_01648 7.4e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMGECGDC_01649 1.6e-258 glpK_1 2.7.1.30 G FGGY family of carbohydrate kinases, C-terminal domain
CMGECGDC_01650 1.3e-176 tktA 2.2.1.1 G Transketolase, pyrimidine binding domain
CMGECGDC_01651 1.2e-154 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
CMGECGDC_01652 6e-188 purR13 K Bacterial regulatory proteins, lacI family
CMGECGDC_01653 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMGECGDC_01654 6.9e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CMGECGDC_01655 1.4e-23
CMGECGDC_01656 8e-94 rsmC 2.1.1.172 J Methyltransferase
CMGECGDC_01657 1.5e-123 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
CMGECGDC_01658 2.2e-47 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CMGECGDC_01659 1.6e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CMGECGDC_01660 2.2e-10
CMGECGDC_01661 2.2e-210 yfdV S Membrane transport protein
CMGECGDC_01662 2e-118 phoU P Plays a role in the regulation of phosphate uptake
CMGECGDC_01663 7e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMGECGDC_01664 4.2e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMGECGDC_01665 2.6e-155 pstA P Phosphate transport system permease protein PstA
CMGECGDC_01666 5.2e-176 pstC P probably responsible for the translocation of the substrate across the membrane
CMGECGDC_01667 1.5e-158 pstS P Phosphate
CMGECGDC_01668 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CMGECGDC_01669 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CMGECGDC_01670 6.2e-102 nusG K Participates in transcription elongation, termination and antitermination
CMGECGDC_01671 7.8e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CMGECGDC_01672 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CMGECGDC_01673 8.1e-173 K helix_turn_helix, arabinose operon control protein
CMGECGDC_01674 3.7e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
CMGECGDC_01675 3.5e-114
CMGECGDC_01676 2.2e-34
CMGECGDC_01677 3.5e-94 sigH K Belongs to the sigma-70 factor family
CMGECGDC_01678 2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMGECGDC_01679 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CMGECGDC_01680 6.8e-278 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMGECGDC_01681 9.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMGECGDC_01682 9.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CMGECGDC_01683 9.5e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
CMGECGDC_01684 7e-52
CMGECGDC_01685 1.9e-266 pepC 3.4.22.40 E Peptidase C1-like family
CMGECGDC_01686 6.4e-184 S AAA domain
CMGECGDC_01687 1.5e-118 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMGECGDC_01688 2.2e-19
CMGECGDC_01689 2.1e-163 czcD P cation diffusion facilitator family transporter
CMGECGDC_01690 4.7e-128 pgm3 5.4.2.11 G Belongs to the phosphoglycerate mutase family
CMGECGDC_01691 5.8e-111 S membrane transporter protein
CMGECGDC_01692 2.5e-118 3.1.3.102, 3.1.3.104, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CMGECGDC_01693 2.5e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
CMGECGDC_01694 2.8e-11
CMGECGDC_01695 3.5e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
CMGECGDC_01696 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CMGECGDC_01697 3e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CMGECGDC_01698 9.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMGECGDC_01699 2.4e-161 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMGECGDC_01700 2.8e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMGECGDC_01701 8.2e-61 rplQ J Ribosomal protein L17
CMGECGDC_01702 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMGECGDC_01703 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CMGECGDC_01704 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CMGECGDC_01705 2.7e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CMGECGDC_01706 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CMGECGDC_01707 2e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CMGECGDC_01708 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CMGECGDC_01709 2e-71 rplO J Binds to the 23S rRNA
CMGECGDC_01710 2.3e-24 rpmD J Ribosomal protein L30
CMGECGDC_01711 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CMGECGDC_01712 2.1e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CMGECGDC_01713 2.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CMGECGDC_01714 9.3e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CMGECGDC_01715 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMGECGDC_01716 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CMGECGDC_01717 4.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CMGECGDC_01718 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CMGECGDC_01719 3.8e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CMGECGDC_01720 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
CMGECGDC_01721 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CMGECGDC_01722 4.9e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CMGECGDC_01723 3.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CMGECGDC_01724 9.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CMGECGDC_01725 4.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CMGECGDC_01726 1.2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CMGECGDC_01727 4.6e-106 rplD J Forms part of the polypeptide exit tunnel
CMGECGDC_01728 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CMGECGDC_01729 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
CMGECGDC_01730 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CMGECGDC_01731 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CMGECGDC_01732 1.5e-68 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CMGECGDC_01733 7.9e-123 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
CMGECGDC_01734 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMGECGDC_01735 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMGECGDC_01736 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CMGECGDC_01737 4.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
CMGECGDC_01739 7.8e-08
CMGECGDC_01740 7.8e-08
CMGECGDC_01741 1.5e-302 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CMGECGDC_01742 1.4e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMGECGDC_01743 2.6e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CMGECGDC_01744 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CMGECGDC_01745 2.2e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CMGECGDC_01746 2.8e-63 yabR J S1 RNA binding domain
CMGECGDC_01747 1.1e-57 divIC D Septum formation initiator
CMGECGDC_01748 2.4e-34 yabO J S4 domain protein
CMGECGDC_01749 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CMGECGDC_01750 1.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CMGECGDC_01751 2.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CMGECGDC_01752 2.9e-128 S (CBS) domain
CMGECGDC_01753 1.4e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CMGECGDC_01754 7.6e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CMGECGDC_01755 3.9e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CMGECGDC_01756 7.7e-263 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CMGECGDC_01757 1.9e-39 rpmE2 J Ribosomal protein L31
CMGECGDC_01758 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
CMGECGDC_01759 3.7e-159 G Sucrose-6F-phosphate phosphohydrolase
CMGECGDC_01760 1.1e-300 ybeC E amino acid
CMGECGDC_01761 1.3e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CMGECGDC_01762 6.7e-44
CMGECGDC_01763 3.7e-51
CMGECGDC_01764 8e-96
CMGECGDC_01766 2.5e-28 K NAD+ binding
CMGECGDC_01767 7.7e-82 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CMGECGDC_01768 1.9e-30
CMGECGDC_01769 1.6e-32 P Belongs to the major facilitator superfamily
CMGECGDC_01770 5.4e-90 lmrB P Belongs to the major facilitator superfamily
CMGECGDC_01771 7e-135 S B3 4 domain
CMGECGDC_01772 1.9e-89 XK27_09675 K Acetyltransferase (GNAT) domain
CMGECGDC_01773 2.7e-43 S Protein of unknown function (DUF3021)
CMGECGDC_01774 1.3e-73 K LytTr DNA-binding domain
CMGECGDC_01775 4e-148 cylB V ABC-2 type transporter
CMGECGDC_01776 2.5e-155 cylA V ABC transporter
CMGECGDC_01777 5.1e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CMGECGDC_01778 7.5e-172 K Helix-turn-helix
CMGECGDC_01779 1.5e-135 K DNA-binding helix-turn-helix protein
CMGECGDC_01780 1.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CMGECGDC_01781 5.2e-221 pbuX F xanthine permease
CMGECGDC_01782 7e-107 S Protein of unknown function (DUF1211)
CMGECGDC_01783 7.4e-160 msmR K AraC-like ligand binding domain
CMGECGDC_01784 2.3e-278 pipD E Dipeptidase
CMGECGDC_01785 1.8e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMGECGDC_01786 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CMGECGDC_01787 3.3e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CMGECGDC_01788 9.5e-68 S Domain of unknown function (DUF1934)
CMGECGDC_01789 7.2e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
CMGECGDC_01790 3.9e-44
CMGECGDC_01791 3.3e-169 2.7.1.2 GK ROK family
CMGECGDC_01792 1.7e-230 ptcC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMGECGDC_01793 7.7e-129 K Helix-turn-helix domain, rpiR family
CMGECGDC_01794 5.2e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMGECGDC_01795 4.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMGECGDC_01796 7.3e-239 S SLAP domain
CMGECGDC_01797 1.5e-86
CMGECGDC_01798 8.4e-90 S SLAP domain
CMGECGDC_01799 9.6e-89 S SLAP domain
CMGECGDC_01800 1.4e-211 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CMGECGDC_01801 1.6e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
CMGECGDC_01802 3.5e-39 veg S Biofilm formation stimulator VEG
CMGECGDC_01803 1.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CMGECGDC_01804 1.6e-92 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CMGECGDC_01805 3.5e-148 tatD L hydrolase, TatD family
CMGECGDC_01806 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CMGECGDC_01807 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
CMGECGDC_01808 3.4e-109 S TPM domain
CMGECGDC_01809 6.5e-92 comEB 3.5.4.12 F MafB19-like deaminase
CMGECGDC_01810 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMGECGDC_01811 4.2e-112 E Belongs to the SOS response-associated peptidase family
CMGECGDC_01813 1.3e-114
CMGECGDC_01814 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMGECGDC_01815 2.4e-69 hsp O Belongs to the small heat shock protein (HSP20) family
CMGECGDC_01816 2.3e-256 pepC 3.4.22.40 E aminopeptidase
CMGECGDC_01817 1.9e-175 oppF P Belongs to the ABC transporter superfamily
CMGECGDC_01818 2.2e-201 oppD P Belongs to the ABC transporter superfamily
CMGECGDC_01819 4e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMGECGDC_01820 1.1e-143 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMGECGDC_01821 7.5e-211 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMGECGDC_01822 4.6e-307 oppA E ABC transporter, substratebinding protein
CMGECGDC_01823 5e-293 oppA E ABC transporter, substratebinding protein
CMGECGDC_01824 1.2e-125 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
CMGECGDC_01825 7.2e-258 pepC 3.4.22.40 E aminopeptidase
CMGECGDC_01827 3.3e-56
CMGECGDC_01828 3.3e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CMGECGDC_01829 6.9e-267 S Fibronectin type III domain
CMGECGDC_01830 0.0 XK27_08315 M Sulfatase
CMGECGDC_01831 6.4e-108 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CMGECGDC_01832 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CMGECGDC_01833 1.6e-102 G Aldose 1-epimerase
CMGECGDC_01834 1.8e-110 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CMGECGDC_01835 2.5e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMGECGDC_01836 1.5e-135
CMGECGDC_01837 7.4e-141
CMGECGDC_01838 9.8e-180 S Oxidoreductase family, NAD-binding Rossmann fold
CMGECGDC_01839 2.4e-46 yjbQ P TrkA C-terminal domain protein
CMGECGDC_01840 6.5e-263 yjbQ P TrkA C-terminal domain protein
CMGECGDC_01841 7.2e-211 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
CMGECGDC_01842 1.1e-207 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CMGECGDC_01843 2.1e-228 S SLAP domain
CMGECGDC_01844 2.2e-175
CMGECGDC_01845 2.4e-256 ica2 GT2 M Glycosyl transferase family group 2
CMGECGDC_01846 3e-60 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
CMGECGDC_01847 3e-203 S SLAP domain
CMGECGDC_01848 6.9e-11
CMGECGDC_01849 1.9e-69
CMGECGDC_01850 0.0 kup P Transport of potassium into the cell
CMGECGDC_01851 0.0 pepO 3.4.24.71 O Peptidase family M13
CMGECGDC_01852 1.1e-228 yttB EGP Major facilitator Superfamily
CMGECGDC_01853 1.1e-233 XK27_04775 S PAS domain
CMGECGDC_01854 6.5e-99 S Iron-sulfur cluster assembly protein
CMGECGDC_01855 8.1e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMGECGDC_01856 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CMGECGDC_01857 3.3e-252 yxbA 6.3.1.12 S ATP-grasp enzyme
CMGECGDC_01858 0.0 asnB 6.3.5.4 E Asparagine synthase
CMGECGDC_01859 3.4e-274 S Calcineurin-like phosphoesterase
CMGECGDC_01860 1.5e-83
CMGECGDC_01861 3.7e-40 tag 3.2.2.20 L glycosylase
CMGECGDC_01862 2.9e-40 tag 3.2.2.20 L glycosylase
CMGECGDC_01863 7.6e-149 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
CMGECGDC_01864 4.8e-132 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
CMGECGDC_01865 2.3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CMGECGDC_01866 1.5e-164 phnD P Phosphonate ABC transporter
CMGECGDC_01867 1.6e-85 uspA T universal stress protein
CMGECGDC_01868 2.2e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
CMGECGDC_01869 1.1e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMGECGDC_01870 1.8e-89 ntd 2.4.2.6 F Nucleoside
CMGECGDC_01871 5.2e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CMGECGDC_01872 0.0 G Belongs to the glycosyl hydrolase 31 family
CMGECGDC_01873 5.6e-160 I alpha/beta hydrolase fold
CMGECGDC_01874 2.4e-131 yibF S overlaps another CDS with the same product name
CMGECGDC_01875 4.4e-203 yibE S overlaps another CDS with the same product name
CMGECGDC_01876 7.2e-90
CMGECGDC_01877 4.7e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CMGECGDC_01878 6.6e-229 S Cysteine-rich secretory protein family
CMGECGDC_01879 1.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CMGECGDC_01880 1.4e-257 glnPH2 P ABC transporter permease
CMGECGDC_01881 2.1e-130
CMGECGDC_01882 2.1e-123 luxT K Bacterial regulatory proteins, tetR family
CMGECGDC_01883 2e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMGECGDC_01884 1.6e-76 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
CMGECGDC_01885 4.1e-46
CMGECGDC_01886 7.1e-122
CMGECGDC_01887 4.7e-204 cycA E Amino acid permease
CMGECGDC_01888 3.6e-220 yifK E Amino acid permease
CMGECGDC_01889 8e-142 puuD S peptidase C26
CMGECGDC_01890 1.7e-241 steT_1 E amino acid
CMGECGDC_01891 1.1e-52 yusE CO Thioredoxin
CMGECGDC_01893 3.6e-117 M1-798 K Rhodanese Homology Domain
CMGECGDC_01894 1.3e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CMGECGDC_01895 1.1e-118 frnE Q DSBA-like thioredoxin domain
CMGECGDC_01896 3e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
CMGECGDC_01897 1.5e-202 4.2.1.126 S Bacterial protein of unknown function (DUF871)
CMGECGDC_01900 2e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMGECGDC_01901 3.2e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CMGECGDC_01902 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CMGECGDC_01903 1.5e-56
CMGECGDC_01904 3.1e-105
CMGECGDC_01905 1.6e-163 yicL EG EamA-like transporter family
CMGECGDC_01906 3.2e-167 EG EamA-like transporter family
CMGECGDC_01907 1.6e-166 EG EamA-like transporter family
CMGECGDC_01908 9.5e-83 M NlpC/P60 family
CMGECGDC_01909 7.6e-134 cobQ S glutamine amidotransferase
CMGECGDC_01910 2.2e-170 L transposase, IS605 OrfB family
CMGECGDC_01911 3.3e-57 S Protein conserved in bacteria
CMGECGDC_01912 2.4e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CMGECGDC_01913 1.4e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CMGECGDC_01914 3.4e-16
CMGECGDC_01915 5e-75
CMGECGDC_01916 6.8e-295 V ABC transporter transmembrane region
CMGECGDC_01917 6.7e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
CMGECGDC_01918 4.8e-179 yvdE K helix_turn _helix lactose operon repressor
CMGECGDC_01919 1.4e-95 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMGECGDC_01920 1.3e-105 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMGECGDC_01921 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
CMGECGDC_01922 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
CMGECGDC_01923 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
CMGECGDC_01924 9.6e-118 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)