ORF_ID e_value Gene_name EC_number CAZy COGs Description
EMDOCAHE_00001 4.4e-247 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EMDOCAHE_00002 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EMDOCAHE_00003 2.2e-34 yaaA S S4 domain protein YaaA
EMDOCAHE_00004 3.3e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EMDOCAHE_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EMDOCAHE_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EMDOCAHE_00007 1.1e-239 L transposase, IS605 OrfB family
EMDOCAHE_00008 2.9e-81 tlpA2 L Transposase IS200 like
EMDOCAHE_00009 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
EMDOCAHE_00010 1.7e-88 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EMDOCAHE_00011 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EMDOCAHE_00012 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EMDOCAHE_00013 1.2e-74 rplI J Binds to the 23S rRNA
EMDOCAHE_00014 7e-243 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EMDOCAHE_00015 1.4e-207 lmrP E Major Facilitator Superfamily
EMDOCAHE_00016 6.3e-50
EMDOCAHE_00017 1.1e-242 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EMDOCAHE_00018 1.2e-188 L PFAM Integrase, catalytic core
EMDOCAHE_00021 6.8e-130 K response regulator
EMDOCAHE_00022 0.0 vicK 2.7.13.3 T Histidine kinase
EMDOCAHE_00023 6.7e-240 yycH S YycH protein
EMDOCAHE_00024 2.7e-143 yycI S YycH protein
EMDOCAHE_00025 6e-154 vicX 3.1.26.11 S domain protein
EMDOCAHE_00026 3e-208 htrA 3.4.21.107 O serine protease
EMDOCAHE_00027 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EMDOCAHE_00028 5.7e-71 K Transcriptional regulator
EMDOCAHE_00029 3.2e-175 malR K Transcriptional regulator, LacI family
EMDOCAHE_00030 3e-251 malT G Major Facilitator
EMDOCAHE_00031 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
EMDOCAHE_00032 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
EMDOCAHE_00033 1.8e-15 natA S ABC transporter, ATP-binding protein
EMDOCAHE_00034 8.8e-16 natA S ABC transporter, ATP-binding protein
EMDOCAHE_00035 1.4e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EMDOCAHE_00036 1.2e-182 D Alpha beta
EMDOCAHE_00037 4.1e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMDOCAHE_00038 9.4e-217 patA 2.6.1.1 E Aminotransferase
EMDOCAHE_00039 2.7e-35
EMDOCAHE_00040 0.0 clpL O associated with various cellular activities
EMDOCAHE_00041 1.8e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EMDOCAHE_00042 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EMDOCAHE_00043 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EMDOCAHE_00044 2.6e-163 yvgN C Aldo keto reductase
EMDOCAHE_00045 4.2e-292 glpQ 3.1.4.46 C phosphodiesterase
EMDOCAHE_00046 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
EMDOCAHE_00047 1.6e-189 ybhR V ABC transporter
EMDOCAHE_00048 6.6e-128 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
EMDOCAHE_00049 2.8e-42 K transcriptional regulator
EMDOCAHE_00050 5.1e-237 L transposase, IS605 OrfB family
EMDOCAHE_00051 2e-77 tlpA2 L Transposase IS200 like
EMDOCAHE_00052 1.1e-37 K transcriptional regulator
EMDOCAHE_00053 7.4e-167 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EMDOCAHE_00054 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EMDOCAHE_00055 1.3e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
EMDOCAHE_00056 1.9e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EMDOCAHE_00057 2.4e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EMDOCAHE_00058 9.4e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EMDOCAHE_00059 4e-17 gntT EG gluconate transmembrane transporter activity
EMDOCAHE_00060 6.9e-47
EMDOCAHE_00061 1.6e-272 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
EMDOCAHE_00062 1.3e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
EMDOCAHE_00063 2.7e-149 metQ1 P Belongs to the nlpA lipoprotein family
EMDOCAHE_00064 2.3e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EMDOCAHE_00065 1.2e-97 metI P ABC transporter permease
EMDOCAHE_00066 3.7e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
EMDOCAHE_00067 3.7e-244 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EMDOCAHE_00068 5.7e-197 brnQ U Component of the transport system for branched-chain amino acids
EMDOCAHE_00069 1.1e-122 iolS C Aldo keto reductase
EMDOCAHE_00070 1.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EMDOCAHE_00071 1.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EMDOCAHE_00072 1.2e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
EMDOCAHE_00073 8.3e-298 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EMDOCAHE_00075 8.7e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EMDOCAHE_00076 0.0 sbcC L Putative exonuclease SbcCD, C subunit
EMDOCAHE_00077 5.7e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EMDOCAHE_00079 4.2e-189 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
EMDOCAHE_00081 1.2e-226 glnP P ABC transporter
EMDOCAHE_00082 4.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EMDOCAHE_00083 1e-251 cycA E Amino acid permease
EMDOCAHE_00084 1.2e-188 L PFAM Integrase, catalytic core
EMDOCAHE_00085 3e-54 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00086 1.3e-31 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00087 2.6e-255 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
EMDOCAHE_00088 3.9e-51 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00089 3.1e-13 lacA 3.2.1.23 G -beta-galactosidase
EMDOCAHE_00090 8.4e-213 nupG F Nucleoside transporter
EMDOCAHE_00091 2.2e-144 rihC 3.2.2.1 F Nucleoside
EMDOCAHE_00092 9e-133 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
EMDOCAHE_00093 1.7e-157 noc K Belongs to the ParB family
EMDOCAHE_00094 1e-145 spo0J K Belongs to the ParB family
EMDOCAHE_00095 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
EMDOCAHE_00096 4.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EMDOCAHE_00097 2.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
EMDOCAHE_00098 1.7e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EMDOCAHE_00099 1.1e-225 L Transposase
EMDOCAHE_00100 1.7e-80 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00101 2e-211 tra L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_00102 1.5e-56 epsF GT4 M Glycosyl transferases group 1
EMDOCAHE_00103 7.1e-155 L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_00104 6.1e-45 L Transposase
EMDOCAHE_00105 8.4e-165 L Integrase core domain
EMDOCAHE_00106 2e-163 S Core-2/I-Branching enzyme
EMDOCAHE_00107 2.1e-137 L COG2801 Transposase and inactivated derivatives
EMDOCAHE_00108 9.8e-39 L Transposase and inactivated derivatives
EMDOCAHE_00109 4.7e-185 L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_00110 8.3e-123 L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_00111 3.2e-225 L Transposase
EMDOCAHE_00112 5.3e-92 S Cupin superfamily (DUF985)
EMDOCAHE_00113 1e-122 K response regulator
EMDOCAHE_00114 5e-207 hpk31 2.7.13.3 T Histidine kinase
EMDOCAHE_00115 1.4e-200 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EMDOCAHE_00116 1.4e-148 azlC E AzlC protein
EMDOCAHE_00117 8.9e-61 azlD S branched-chain amino acid
EMDOCAHE_00118 5.1e-60 ydeN S Serine hydrolase
EMDOCAHE_00119 3.7e-229 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
EMDOCAHE_00120 2.1e-238 L transposase, IS605 OrfB family
EMDOCAHE_00121 6.8e-81 tlpA2 L Transposase IS200 like
EMDOCAHE_00122 1.9e-225 L Transposase
EMDOCAHE_00123 8.3e-51 L Helix-turn-helix domain
EMDOCAHE_00124 6.2e-85 L hmm pf00665
EMDOCAHE_00125 1.4e-163 K AI-2E family transporter
EMDOCAHE_00126 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EMDOCAHE_00127 4e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EMDOCAHE_00128 4.5e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EMDOCAHE_00129 8.1e-254 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EMDOCAHE_00130 6.1e-172 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
EMDOCAHE_00131 9.1e-236 S response to antibiotic
EMDOCAHE_00132 2.5e-135 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EMDOCAHE_00133 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EMDOCAHE_00134 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EMDOCAHE_00135 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EMDOCAHE_00136 5.7e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EMDOCAHE_00137 1.1e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EMDOCAHE_00138 1.8e-107 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EMDOCAHE_00139 2.9e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EMDOCAHE_00140 4.5e-241 purD 6.3.4.13 F Belongs to the GARS family
EMDOCAHE_00141 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EMDOCAHE_00142 5.1e-223 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
EMDOCAHE_00143 1.9e-178
EMDOCAHE_00144 8.5e-47 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
EMDOCAHE_00145 5e-53 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
EMDOCAHE_00146 0.0 copA 3.6.3.54 P P-type ATPase
EMDOCAHE_00147 3.8e-30 EGP Major facilitator Superfamily
EMDOCAHE_00148 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
EMDOCAHE_00149 9.8e-77
EMDOCAHE_00151 1.9e-214 tra L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_00152 1.2e-55 L Helix-turn-helix domain
EMDOCAHE_00153 6.7e-156 L hmm pf00665
EMDOCAHE_00154 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_00155 8.1e-218 lacS G Transporter
EMDOCAHE_00156 2.3e-83 lacR K Transcriptional regulator
EMDOCAHE_00157 2.9e-137 L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_00158 6.1e-29 S Domain of unknown function (DUF4767)
EMDOCAHE_00159 5.4e-44 S Tautomerase enzyme
EMDOCAHE_00160 2.1e-22 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
EMDOCAHE_00161 7.8e-120 pnb C nitroreductase
EMDOCAHE_00162 3.2e-83 S Alpha/beta hydrolase family
EMDOCAHE_00163 1.2e-79 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EMDOCAHE_00164 6.2e-24 C reductase
EMDOCAHE_00165 7.7e-46 C Aldo keto reductase
EMDOCAHE_00169 7.6e-82 tlpA2 L Transposase IS200 like
EMDOCAHE_00170 9.3e-239 L transposase, IS605 OrfB family
EMDOCAHE_00171 3.1e-93 P Cadmium resistance transporter
EMDOCAHE_00172 3.9e-31 ydzE EG spore germination
EMDOCAHE_00173 1.5e-53 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EMDOCAHE_00174 2.3e-42
EMDOCAHE_00175 3.4e-269 isdH M Iron Transport-associated domain
EMDOCAHE_00176 1e-94 M Iron Transport-associated domain
EMDOCAHE_00177 6.3e-149 isdE P Periplasmic binding protein
EMDOCAHE_00178 5.4e-151 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EMDOCAHE_00179 4.2e-141 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
EMDOCAHE_00180 3.8e-235 kgtP EGP Sugar (and other) transporter
EMDOCAHE_00181 9.8e-10 M domain protein
EMDOCAHE_00182 3.9e-56
EMDOCAHE_00183 4.9e-159 xth 3.1.11.2 L exodeoxyribonuclease III
EMDOCAHE_00184 9.8e-77
EMDOCAHE_00185 2.6e-180 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMDOCAHE_00186 3.8e-80 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00187 7e-36 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
EMDOCAHE_00188 3e-85 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
EMDOCAHE_00189 1.3e-63 pucR QT Purine catabolism regulatory protein-like family
EMDOCAHE_00190 4.1e-134 allB 3.5.2.5 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EMDOCAHE_00191 1.7e-98 allC 3.5.1.6, 3.5.1.87, 3.5.3.9 E Peptidase family M20/M25/M40
EMDOCAHE_00192 1.2e-202 allD 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
EMDOCAHE_00193 6e-19 sucD 6.2.1.5 C CoA-ligase
EMDOCAHE_00194 1.7e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
EMDOCAHE_00195 3e-124 C nitroreductase
EMDOCAHE_00196 4.6e-137 E GDSL-like Lipase/Acylhydrolase family
EMDOCAHE_00197 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
EMDOCAHE_00198 1.9e-197 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
EMDOCAHE_00199 0.0 pepN 3.4.11.2 E aminopeptidase
EMDOCAHE_00200 1.4e-62 morA C Aldo keto reductase
EMDOCAHE_00201 5.8e-166 K Transcriptional regulator
EMDOCAHE_00202 2.3e-24 phaG GT1 I carboxylic ester hydrolase activity
EMDOCAHE_00203 2.1e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EMDOCAHE_00205 4.2e-147 metQ_4 P Belongs to the nlpA lipoprotein family
EMDOCAHE_00206 1.2e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EMDOCAHE_00207 0.0 helD 3.6.4.12 L DNA helicase
EMDOCAHE_00208 7.3e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
EMDOCAHE_00209 4e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EMDOCAHE_00210 2.2e-187
EMDOCAHE_00211 4.4e-129 cobB K SIR2 family
EMDOCAHE_00212 5.3e-212 norA EGP Major facilitator Superfamily
EMDOCAHE_00213 9.5e-163 yunF F Protein of unknown function DUF72
EMDOCAHE_00214 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EMDOCAHE_00215 1.8e-147 tatD L hydrolase, TatD family
EMDOCAHE_00216 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EMDOCAHE_00217 9.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EMDOCAHE_00218 1.3e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EMDOCAHE_00219 1.5e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
EMDOCAHE_00220 5.4e-95 fhuC P ABC transporter
EMDOCAHE_00221 2.1e-127 znuB U ABC 3 transport family
EMDOCAHE_00222 2.4e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
EMDOCAHE_00223 7.3e-205 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EMDOCAHE_00224 3.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EMDOCAHE_00225 3e-32
EMDOCAHE_00226 1.4e-142 yxeH S hydrolase
EMDOCAHE_00227 5.7e-266 ywfO S HD domain protein
EMDOCAHE_00228 3.2e-74 ywiB S Domain of unknown function (DUF1934)
EMDOCAHE_00229 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EMDOCAHE_00230 1.1e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EMDOCAHE_00231 2.3e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EMDOCAHE_00232 6e-41 rpmE2 J Ribosomal protein L31
EMDOCAHE_00233 3.3e-29 mdtG EGP Major facilitator Superfamily
EMDOCAHE_00234 4.7e-123 srtA 3.4.22.70 M sortase family
EMDOCAHE_00235 2.9e-81 tlpA2 L Transposase IS200 like
EMDOCAHE_00236 7.1e-239 L transposase, IS605 OrfB family
EMDOCAHE_00237 9e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EMDOCAHE_00238 8.7e-88 lemA S LemA family
EMDOCAHE_00239 4.9e-157 htpX O Belongs to the peptidase M48B family
EMDOCAHE_00240 6.2e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EMDOCAHE_00241 1.9e-254 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EMDOCAHE_00242 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EMDOCAHE_00243 2.8e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EMDOCAHE_00244 5e-57 L Toxic component of a toxin-antitoxin (TA) module
EMDOCAHE_00245 8.1e-114 S (CBS) domain
EMDOCAHE_00246 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EMDOCAHE_00247 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EMDOCAHE_00248 1.6e-39 yabO J S4 domain protein
EMDOCAHE_00249 1.5e-56 divIC D Septum formation initiator
EMDOCAHE_00250 3e-87 yabR J RNA binding
EMDOCAHE_00251 1.4e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EMDOCAHE_00252 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EMDOCAHE_00253 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EMDOCAHE_00254 7.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EMDOCAHE_00255 3.2e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EMDOCAHE_00256 2.8e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EMDOCAHE_00259 9.8e-77
EMDOCAHE_00262 3.1e-245 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EMDOCAHE_00263 1.6e-224 L Transposase
EMDOCAHE_00264 1.1e-41 K Helix-turn-helix domain
EMDOCAHE_00265 9e-24 XK26_04895
EMDOCAHE_00266 1.2e-167 D nuclear chromosome segregation
EMDOCAHE_00267 3.7e-258 dtpT U amino acid peptide transporter
EMDOCAHE_00268 1.7e-164 yjjH S Calcineurin-like phosphoesterase
EMDOCAHE_00271 3.3e-115
EMDOCAHE_00272 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EMDOCAHE_00273 1.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
EMDOCAHE_00274 1.1e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EMDOCAHE_00275 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EMDOCAHE_00276 0.0 yhgF K Tex-like protein N-terminal domain protein
EMDOCAHE_00277 2.4e-83 ydcK S Belongs to the SprT family
EMDOCAHE_00279 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
EMDOCAHE_00280 1.8e-189 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
EMDOCAHE_00281 2.3e-168 mleP2 S Sodium Bile acid symporter family
EMDOCAHE_00282 5.2e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EMDOCAHE_00283 1.3e-167 I alpha/beta hydrolase fold
EMDOCAHE_00284 1.2e-263 pepC 3.4.22.40 E Peptidase C1-like family
EMDOCAHE_00285 5.3e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
EMDOCAHE_00286 1.1e-116 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EMDOCAHE_00287 3.3e-58 tlpA2 L Transposase IS200 like
EMDOCAHE_00288 6.4e-240 L transposase, IS605 OrfB family
EMDOCAHE_00289 2.8e-54 HA62_12640 S GCN5-related N-acetyl-transferase
EMDOCAHE_00290 1.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
EMDOCAHE_00291 5.6e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EMDOCAHE_00292 2.7e-205 yacL S domain protein
EMDOCAHE_00293 9.6e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EMDOCAHE_00294 7.8e-100 ywlG S Belongs to the UPF0340 family
EMDOCAHE_00295 6.5e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EMDOCAHE_00296 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EMDOCAHE_00297 1.5e-135 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EMDOCAHE_00298 1.1e-104 sigH K Belongs to the sigma-70 factor family
EMDOCAHE_00299 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EMDOCAHE_00300 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EMDOCAHE_00301 5.9e-97 nusG K Participates in transcription elongation, termination and antitermination
EMDOCAHE_00302 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EMDOCAHE_00303 5.7e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EMDOCAHE_00304 4.8e-190 L Helix-turn-helix domain
EMDOCAHE_00305 1.7e-243 steT E amino acid
EMDOCAHE_00306 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EMDOCAHE_00307 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EMDOCAHE_00308 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
EMDOCAHE_00309 4.1e-176 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
EMDOCAHE_00310 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
EMDOCAHE_00311 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EMDOCAHE_00312 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EMDOCAHE_00314 6.6e-246 brnQ U Component of the transport system for branched-chain amino acids
EMDOCAHE_00315 1.9e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EMDOCAHE_00316 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EMDOCAHE_00317 2.6e-35 nrdH O Glutaredoxin
EMDOCAHE_00318 6.3e-80 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EMDOCAHE_00320 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EMDOCAHE_00321 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EMDOCAHE_00322 1.1e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EMDOCAHE_00323 2.4e-21 S Protein of unknown function (DUF2508)
EMDOCAHE_00324 1.3e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EMDOCAHE_00325 1.2e-52 yaaQ S Cyclic-di-AMP receptor
EMDOCAHE_00326 3.2e-192 holB 2.7.7.7 L DNA polymerase III
EMDOCAHE_00327 1.5e-55 yabA L Involved in initiation control of chromosome replication
EMDOCAHE_00328 1.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EMDOCAHE_00329 3.3e-146 fat 3.1.2.21 I Acyl-ACP thioesterase
EMDOCAHE_00330 1.1e-281 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
EMDOCAHE_00331 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EMDOCAHE_00332 2.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
EMDOCAHE_00333 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EMDOCAHE_00334 6.7e-148 KT YcbB domain
EMDOCAHE_00335 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EMDOCAHE_00336 1.4e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
EMDOCAHE_00337 8.2e-240 arcA 3.5.3.6 E Arginine
EMDOCAHE_00338 1.1e-259 E Arginine ornithine antiporter
EMDOCAHE_00339 9.6e-219 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
EMDOCAHE_00340 6.5e-215 arcT 2.6.1.1 E Aminotransferase
EMDOCAHE_00341 4.8e-190 L Helix-turn-helix domain
EMDOCAHE_00342 5.8e-132 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
EMDOCAHE_00343 3.9e-110 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
EMDOCAHE_00344 1.2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EMDOCAHE_00346 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EMDOCAHE_00347 9.2e-25 marR K Transcriptional regulator, MarR family
EMDOCAHE_00348 2.5e-36 marR K Transcriptional regulator, MarR family
EMDOCAHE_00349 2.2e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EMDOCAHE_00350 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EMDOCAHE_00351 2.8e-171 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EMDOCAHE_00352 1e-128 IQ reductase
EMDOCAHE_00353 6e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EMDOCAHE_00354 5.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EMDOCAHE_00355 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EMDOCAHE_00356 1.6e-263 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
EMDOCAHE_00357 3.5e-42 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EMDOCAHE_00358 1.7e-80 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00359 1.3e-99 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EMDOCAHE_00360 5.2e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
EMDOCAHE_00361 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
EMDOCAHE_00362 9.7e-92 bioY S BioY family
EMDOCAHE_00363 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EMDOCAHE_00364 0.0 uup S ABC transporter, ATP-binding protein
EMDOCAHE_00365 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EMDOCAHE_00366 7.4e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EMDOCAHE_00367 4.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EMDOCAHE_00368 0.0 ydaO E amino acid
EMDOCAHE_00369 8.9e-38
EMDOCAHE_00370 2.5e-79 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00371 1.2e-112 yvyE 3.4.13.9 S YigZ family
EMDOCAHE_00372 6.5e-251 comFA L Helicase C-terminal domain protein
EMDOCAHE_00373 3e-127 comFC S Competence protein
EMDOCAHE_00374 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EMDOCAHE_00375 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EMDOCAHE_00376 4.5e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EMDOCAHE_00377 1.2e-52 KT PspC domain protein
EMDOCAHE_00378 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
EMDOCAHE_00379 1e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EMDOCAHE_00380 4e-161 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EMDOCAHE_00381 5.3e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EMDOCAHE_00382 6e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EMDOCAHE_00383 2.3e-147 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
EMDOCAHE_00384 5.9e-227 mtnE 2.6.1.83 E Aminotransferase
EMDOCAHE_00385 7.6e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EMDOCAHE_00386 2.6e-30 tlpA2 L Transposase IS200 like
EMDOCAHE_00387 1.7e-237 L transposase, IS605 OrfB family
EMDOCAHE_00388 1.5e-76 yphH S Cupin domain
EMDOCAHE_00389 1.1e-23 L Helix-turn-helix domain
EMDOCAHE_00390 2.2e-165 L PFAM Integrase catalytic region
EMDOCAHE_00391 1.7e-131 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EMDOCAHE_00392 1.3e-153 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
EMDOCAHE_00393 9.8e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EMDOCAHE_00394 3.8e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EMDOCAHE_00395 6.2e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EMDOCAHE_00396 5.4e-136 cof S haloacid dehalogenase-like hydrolase
EMDOCAHE_00397 1.1e-19 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EMDOCAHE_00398 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EMDOCAHE_00399 6.8e-113 yfbR S HD containing hydrolase-like enzyme
EMDOCAHE_00401 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EMDOCAHE_00402 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EMDOCAHE_00403 2.2e-204
EMDOCAHE_00404 2.1e-160 rapZ S Displays ATPase and GTPase activities
EMDOCAHE_00405 1.7e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EMDOCAHE_00406 4.2e-167 whiA K May be required for sporulation
EMDOCAHE_00407 7.9e-76 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EMDOCAHE_00408 7.2e-17 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EMDOCAHE_00409 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EMDOCAHE_00413 2.2e-52 S Putative inner membrane protein (DUF1819)
EMDOCAHE_00414 1.4e-101 S Domain of unknown function (DUF1788)
EMDOCAHE_00415 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
EMDOCAHE_00416 0.0 2.1.1.72 V Eco57I restriction-modification methylase
EMDOCAHE_00417 3.6e-191 L Belongs to the 'phage' integrase family
EMDOCAHE_00418 4.4e-218 V Type II restriction enzyme, methylase subunits
EMDOCAHE_00419 0.0 S PglZ domain
EMDOCAHE_00420 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
EMDOCAHE_00421 0.0 yfjM S Protein of unknown function DUF262
EMDOCAHE_00422 1.1e-23 L Helix-turn-helix domain
EMDOCAHE_00423 6.3e-165 L PFAM Integrase catalytic region
EMDOCAHE_00424 7.8e-100 L hmm pf00665
EMDOCAHE_00425 1e-15
EMDOCAHE_00426 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EMDOCAHE_00427 6.6e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EMDOCAHE_00428 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EMDOCAHE_00429 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EMDOCAHE_00430 1.5e-253 yifK E Amino acid permease
EMDOCAHE_00431 3.2e-289 clcA P chloride
EMDOCAHE_00432 4.5e-33 secG U Preprotein translocase
EMDOCAHE_00433 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EMDOCAHE_00434 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EMDOCAHE_00435 7.9e-108 yxjI
EMDOCAHE_00436 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EMDOCAHE_00437 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EMDOCAHE_00438 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
EMDOCAHE_00439 1.6e-88 K Acetyltransferase (GNAT) domain
EMDOCAHE_00440 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
EMDOCAHE_00441 5.7e-166 murB 1.3.1.98 M Cell wall formation
EMDOCAHE_00442 7.8e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EMDOCAHE_00443 9.1e-116 ybbR S YbbR-like protein
EMDOCAHE_00444 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EMDOCAHE_00445 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EMDOCAHE_00446 1.5e-52
EMDOCAHE_00447 7.8e-210 oatA I Acyltransferase
EMDOCAHE_00448 4e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
EMDOCAHE_00449 1.3e-68 lytE M Lysin motif
EMDOCAHE_00450 9.2e-160 MA20_14895 S Conserved hypothetical protein 698
EMDOCAHE_00451 9.6e-169 K LysR substrate binding domain
EMDOCAHE_00452 1.9e-130 manA 5.3.1.8 G mannose-6-phosphate isomerase
EMDOCAHE_00453 6.6e-148 yitS S EDD domain protein, DegV family
EMDOCAHE_00454 6.5e-90 racA K Domain of unknown function (DUF1836)
EMDOCAHE_00455 2.3e-181 yfeX P Peroxidase
EMDOCAHE_00456 4.5e-180 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
EMDOCAHE_00457 3.5e-114 manY G PTS system
EMDOCAHE_00458 3e-170 manN G system, mannose fructose sorbose family IID component
EMDOCAHE_00459 3.5e-57 S Domain of unknown function (DUF956)
EMDOCAHE_00461 2.8e-131 K response regulator
EMDOCAHE_00462 1.3e-250 yclK 2.7.13.3 T Histidine kinase
EMDOCAHE_00463 5.9e-152 glcU U sugar transport
EMDOCAHE_00464 1.1e-23 L Helix-turn-helix domain
EMDOCAHE_00465 2.2e-165 L PFAM Integrase catalytic region
EMDOCAHE_00466 2.9e-81 tlpA2 L Transposase IS200 like
EMDOCAHE_00467 2.7e-238 L transposase, IS605 OrfB family
EMDOCAHE_00468 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
EMDOCAHE_00469 0.0 trxB2 1.8.1.9 C Thioredoxin domain
EMDOCAHE_00470 8.2e-257 pgi 5.3.1.9 G Belongs to the GPI family
EMDOCAHE_00472 1.6e-85 K GNAT family
EMDOCAHE_00473 1.8e-122 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
EMDOCAHE_00474 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
EMDOCAHE_00475 1.7e-145 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EMDOCAHE_00476 2.1e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
EMDOCAHE_00478 1e-56
EMDOCAHE_00480 2.3e-07
EMDOCAHE_00481 1.8e-78 K Winged helix DNA-binding domain
EMDOCAHE_00482 0.0 lmrA V ABC transporter, ATP-binding protein
EMDOCAHE_00483 0.0 yfiC V ABC transporter
EMDOCAHE_00484 2.8e-193 ampC V Beta-lactamase
EMDOCAHE_00485 1.9e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EMDOCAHE_00486 2.8e-48
EMDOCAHE_00487 1.3e-139 cobQ S CobB/CobQ-like glutamine amidotransferase domain
EMDOCAHE_00488 3.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
EMDOCAHE_00489 3.2e-109 tdk 2.7.1.21 F thymidine kinase
EMDOCAHE_00490 2.5e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EMDOCAHE_00491 3.2e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EMDOCAHE_00492 9.8e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EMDOCAHE_00493 1.7e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EMDOCAHE_00494 1.2e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EMDOCAHE_00495 4e-245 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EMDOCAHE_00496 1.7e-183 yibE S overlaps another CDS with the same product name
EMDOCAHE_00497 4.2e-125 yibF S overlaps another CDS with the same product name
EMDOCAHE_00498 5.4e-218 pyrP F Permease
EMDOCAHE_00499 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
EMDOCAHE_00500 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EMDOCAHE_00501 2.6e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EMDOCAHE_00502 7.4e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EMDOCAHE_00503 2.1e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EMDOCAHE_00504 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EMDOCAHE_00505 1.7e-252 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EMDOCAHE_00506 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EMDOCAHE_00507 2.8e-29 S Protein of unknown function (DUF1146)
EMDOCAHE_00508 1.9e-220 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
EMDOCAHE_00509 2.6e-183 mbl D Cell shape determining protein MreB Mrl
EMDOCAHE_00510 7.9e-32 S Protein of unknown function (DUF2969)
EMDOCAHE_00511 5.8e-222 rodA D Belongs to the SEDS family
EMDOCAHE_00513 6.9e-181 S Protein of unknown function (DUF2785)
EMDOCAHE_00514 7.7e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EMDOCAHE_00515 8.4e-151 2.3.1.19 K Helix-turn-helix XRE-family like proteins
EMDOCAHE_00516 2.3e-81 usp6 T universal stress protein
EMDOCAHE_00518 4.9e-235 rarA L recombination factor protein RarA
EMDOCAHE_00519 1.7e-84 yueI S Protein of unknown function (DUF1694)
EMDOCAHE_00520 3.3e-76 4.4.1.5 E Glyoxalase
EMDOCAHE_00521 2.4e-133 S Membrane
EMDOCAHE_00522 4.6e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EMDOCAHE_00523 5.5e-26 S YjcQ protein
EMDOCAHE_00525 1.8e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EMDOCAHE_00526 9.8e-308 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EMDOCAHE_00527 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
EMDOCAHE_00528 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EMDOCAHE_00529 1.4e-202 EG GntP family permease
EMDOCAHE_00530 2.3e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EMDOCAHE_00531 4e-245 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EMDOCAHE_00532 4.5e-46 tra L EVIDENCE BY HOMOLOGY BIO14.04 Transposon related functions. BELONGS TO THE IS30 FAMILY OF TRANSPOSASE. There are 15 such elements in the chromosome
EMDOCAHE_00533 1.1e-133 L PFAM transposase, IS4 family protein
EMDOCAHE_00534 8e-155 L Transposase
EMDOCAHE_00535 1.1e-39 L Transposase
EMDOCAHE_00536 2.2e-81 tlpA2 L Transposase IS200 like
EMDOCAHE_00537 5.4e-239 L transposase, IS605 OrfB family
EMDOCAHE_00540 4.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EMDOCAHE_00541 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EMDOCAHE_00542 1.7e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EMDOCAHE_00543 7.1e-186 L PFAM Integrase catalytic region
EMDOCAHE_00544 2.5e-115 radC L DNA repair protein
EMDOCAHE_00545 1.9e-181 mreB D cell shape determining protein MreB
EMDOCAHE_00546 3.7e-146 mreC M Involved in formation and maintenance of cell shape
EMDOCAHE_00547 6.6e-93 mreD M rod shape-determining protein MreD
EMDOCAHE_00548 1.4e-108 glnP P ABC transporter permease
EMDOCAHE_00549 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EMDOCAHE_00550 2.4e-161 aatB ET ABC transporter substrate-binding protein
EMDOCAHE_00551 1.5e-231 ymfF S Peptidase M16 inactive domain protein
EMDOCAHE_00552 5.8e-252 ymfH S Peptidase M16
EMDOCAHE_00553 5.4e-96 ymfM S Helix-turn-helix domain
EMDOCAHE_00554 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EMDOCAHE_00555 1.9e-231 cinA 3.5.1.42 S Belongs to the CinA family
EMDOCAHE_00556 2.2e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EMDOCAHE_00557 8.4e-205 rny S Endoribonuclease that initiates mRNA decay
EMDOCAHE_00558 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EMDOCAHE_00559 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EMDOCAHE_00560 1.9e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EMDOCAHE_00561 2.9e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EMDOCAHE_00562 1.1e-175 2.4.2.29 F queuine tRNA-ribosyltransferase activity
EMDOCAHE_00563 1.6e-41 yajC U Preprotein translocase
EMDOCAHE_00564 6.8e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
EMDOCAHE_00565 6.4e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EMDOCAHE_00566 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EMDOCAHE_00567 1.2e-42 yrzL S Belongs to the UPF0297 family
EMDOCAHE_00568 9.6e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EMDOCAHE_00569 5.7e-33 yrzB S Belongs to the UPF0473 family
EMDOCAHE_00570 1.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EMDOCAHE_00571 4.7e-91 cvpA S Colicin V production protein
EMDOCAHE_00572 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EMDOCAHE_00573 1e-53 trxA O Belongs to the thioredoxin family
EMDOCAHE_00574 1.5e-225 clcA_2 P Chloride transporter, ClC family
EMDOCAHE_00575 1e-93 yslB S Protein of unknown function (DUF2507)
EMDOCAHE_00576 5.4e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EMDOCAHE_00577 1.1e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EMDOCAHE_00578 8.8e-95 S Phosphoesterase
EMDOCAHE_00579 4.9e-151 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
EMDOCAHE_00580 2e-155 ykuT M mechanosensitive ion channel
EMDOCAHE_00581 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EMDOCAHE_00582 4.9e-70
EMDOCAHE_00583 4.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
EMDOCAHE_00584 2.2e-185 ccpA K catabolite control protein A
EMDOCAHE_00585 3.6e-85
EMDOCAHE_00586 3.7e-134 yebC K Transcriptional regulatory protein
EMDOCAHE_00587 4.9e-84 mltD CBM50 M PFAM NLP P60 protein
EMDOCAHE_00588 9e-304 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
EMDOCAHE_00589 2.7e-177 comGA NU Type II IV secretion system protein
EMDOCAHE_00590 9.6e-157 comGB NU type II secretion system
EMDOCAHE_00591 1.1e-47 comGC U competence protein ComGC
EMDOCAHE_00592 2.3e-15 NU general secretion pathway protein
EMDOCAHE_00594 1e-14
EMDOCAHE_00596 3.3e-158 ytxK 2.1.1.72 L N-6 DNA Methylase
EMDOCAHE_00597 9.5e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EMDOCAHE_00598 5.3e-110 S Calcineurin-like phosphoesterase
EMDOCAHE_00599 1.2e-97 yutD S Protein of unknown function (DUF1027)
EMDOCAHE_00600 6.6e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EMDOCAHE_00601 1.4e-23 S Protein of unknown function (DUF1461)
EMDOCAHE_00602 1e-103 dedA S SNARE-like domain protein
EMDOCAHE_00603 9.8e-77
EMDOCAHE_00623 3.5e-16 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EMDOCAHE_00624 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EMDOCAHE_00625 4.5e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EMDOCAHE_00626 1e-203 coiA 3.6.4.12 S Competence protein
EMDOCAHE_00627 1.8e-113 yjbH Q Thioredoxin
EMDOCAHE_00628 6e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
EMDOCAHE_00629 1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EMDOCAHE_00630 8.2e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
EMDOCAHE_00631 8.8e-195 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
EMDOCAHE_00632 3.3e-163 rrmA 2.1.1.187 H Methyltransferase
EMDOCAHE_00633 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EMDOCAHE_00634 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EMDOCAHE_00635 1.2e-07 S Protein of unknown function (DUF4044)
EMDOCAHE_00636 5.8e-58
EMDOCAHE_00637 5.6e-79 mraZ K Belongs to the MraZ family
EMDOCAHE_00638 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EMDOCAHE_00639 3.5e-08 ftsL D Cell division protein FtsL
EMDOCAHE_00640 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
EMDOCAHE_00641 3.5e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EMDOCAHE_00642 4.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EMDOCAHE_00643 2.8e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EMDOCAHE_00644 8.4e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EMDOCAHE_00645 3.5e-223 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EMDOCAHE_00646 9e-221 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EMDOCAHE_00647 2.5e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EMDOCAHE_00648 6.8e-41 yggT S YGGT family
EMDOCAHE_00649 2.9e-145 ylmH S S4 domain protein
EMDOCAHE_00650 4.8e-112 divIVA D DivIVA domain protein
EMDOCAHE_00652 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EMDOCAHE_00653 1.2e-32 cspB K Cold shock protein
EMDOCAHE_00654 7.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
EMDOCAHE_00656 1.3e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EMDOCAHE_00657 2.2e-57 XK27_04120 S Putative amino acid metabolism
EMDOCAHE_00658 2.9e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EMDOCAHE_00659 3e-306 S amidohydrolase
EMDOCAHE_00660 4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EMDOCAHE_00661 2.7e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
EMDOCAHE_00662 7.1e-124 S Repeat protein
EMDOCAHE_00663 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EMDOCAHE_00664 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EMDOCAHE_00665 4.2e-74 spx4 1.20.4.1 P ArsC family
EMDOCAHE_00666 2e-188 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
EMDOCAHE_00667 2.2e-31 ykzG S Belongs to the UPF0356 family
EMDOCAHE_00668 1.2e-74
EMDOCAHE_00669 7.5e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EMDOCAHE_00670 2.4e-49 yktA S Belongs to the UPF0223 family
EMDOCAHE_00671 5.3e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EMDOCAHE_00672 0.0 typA T GTP-binding protein TypA
EMDOCAHE_00673 3.5e-211 ftsW D Belongs to the SEDS family
EMDOCAHE_00674 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
EMDOCAHE_00675 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
EMDOCAHE_00676 3.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EMDOCAHE_00677 6.7e-198 ylbL T Belongs to the peptidase S16 family
EMDOCAHE_00678 1.3e-90 comEA L Competence protein ComEA
EMDOCAHE_00679 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
EMDOCAHE_00680 0.0 comEC S Competence protein ComEC
EMDOCAHE_00681 1.8e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
EMDOCAHE_00682 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
EMDOCAHE_00683 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EMDOCAHE_00684 3.8e-226 L transposase, IS605 OrfB family
EMDOCAHE_00685 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EMDOCAHE_00686 1e-162 S Tetratricopeptide repeat
EMDOCAHE_00687 3.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EMDOCAHE_00688 5.7e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EMDOCAHE_00689 1.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EMDOCAHE_00690 2.3e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
EMDOCAHE_00691 8.3e-53 MA20_27270 S mazG nucleotide pyrophosphohydrolase
EMDOCAHE_00693 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EMDOCAHE_00694 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EMDOCAHE_00695 3.3e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EMDOCAHE_00696 8.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EMDOCAHE_00697 1.9e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EMDOCAHE_00698 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
EMDOCAHE_00699 2.6e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EMDOCAHE_00700 5.6e-62 S Domain of unknown function (DUF4440)
EMDOCAHE_00701 8.6e-187 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMDOCAHE_00702 2.1e-151 tesE Q hydratase
EMDOCAHE_00703 1.7e-41 K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
EMDOCAHE_00704 8.9e-98 ywrO S Flavodoxin-like fold
EMDOCAHE_00705 4.9e-20 S Protein conserved in bacteria
EMDOCAHE_00706 3e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
EMDOCAHE_00707 2e-51 S Sugar efflux transporter for intercellular exchange
EMDOCAHE_00708 5.9e-17 xre K Helix-turn-helix domain
EMDOCAHE_00709 8.2e-199 gldA 1.1.1.6 C dehydrogenase
EMDOCAHE_00710 9.5e-118 IQ Enoyl-(Acyl carrier protein) reductase
EMDOCAHE_00711 1e-104 S Bacterial transferase hexapeptide (six repeats)
EMDOCAHE_00714 2.7e-189 EGP Major facilitator Superfamily
EMDOCAHE_00715 3.3e-145 L Transposase and inactivated derivatives
EMDOCAHE_00717 0.0 asnB 6.3.5.4 E Aluminium induced protein
EMDOCAHE_00718 3.4e-16 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
EMDOCAHE_00719 3e-14
EMDOCAHE_00720 6.7e-184 scrR3 K Transcriptional regulator, LacI family
EMDOCAHE_00721 1.3e-78 F Nucleoside 2-deoxyribosyltransferase
EMDOCAHE_00722 5.1e-89
EMDOCAHE_00724 2.2e-90 L Belongs to the 'phage' integrase family
EMDOCAHE_00725 3.9e-09 E Zn peptidase
EMDOCAHE_00726 2.7e-11 XK27_10050 K Peptidase S24-like
EMDOCAHE_00728 2.2e-11 S Domain of unknown function (DUF771)
EMDOCAHE_00731 1.7e-15
EMDOCAHE_00740 7.1e-18 1.20.4.1 P ArsC family
EMDOCAHE_00742 1.2e-227 tnp L MULE transposase domain
EMDOCAHE_00744 6.2e-09
EMDOCAHE_00749 2.2e-73 endA F DNA RNA non-specific endonuclease
EMDOCAHE_00752 1.9e-228 tnp L MULE transposase domain
EMDOCAHE_00753 1.6e-37 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EMDOCAHE_00754 2.7e-52 ruvB 3.6.4.12 L four-way junction helicase activity
EMDOCAHE_00756 5.5e-228 tnp L MULE transposase domain
EMDOCAHE_00757 1e-146 L Integrase core domain
EMDOCAHE_00758 5e-41 tnp L MULE transposase domain
EMDOCAHE_00759 2.3e-245 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EMDOCAHE_00760 9.2e-79 natA S Domain of unknown function (DUF4162)
EMDOCAHE_00761 7.9e-57 ysdA CP transmembrane transport
EMDOCAHE_00762 8.5e-229 tnp L MULE transposase domain
EMDOCAHE_00764 8.7e-156 L hmm pf00665
EMDOCAHE_00765 1.3e-170 L Integrase core domain
EMDOCAHE_00766 4.3e-46 L Transposase
EMDOCAHE_00767 7.2e-228 tnp L MULE transposase domain
EMDOCAHE_00769 1.1e-113 L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_00770 6.6e-17
EMDOCAHE_00771 9.8e-30
EMDOCAHE_00772 7.8e-58 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
EMDOCAHE_00773 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
EMDOCAHE_00774 7.1e-132 tnp L DDE domain
EMDOCAHE_00775 2e-23 2.1.1.144, 2.1.1.197 S DREV methyltransferase
EMDOCAHE_00776 3.7e-155 L Integrase core domain
EMDOCAHE_00777 1.9e-228 tnp L MULE transposase domain
EMDOCAHE_00778 1.2e-169 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00779 3.8e-215 tra L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_00780 1.3e-294 cadA P P-type ATPase
EMDOCAHE_00781 1.2e-21 L Integrase
EMDOCAHE_00782 4.1e-175 L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_00783 8.3e-51 L Helix-turn-helix domain
EMDOCAHE_00784 6.2e-85 L hmm pf00665
EMDOCAHE_00785 1.2e-239 EGP Major Facilitator Superfamily
EMDOCAHE_00786 0.0 mco Q Multicopper oxidase
EMDOCAHE_00787 4.7e-25
EMDOCAHE_00788 1.5e-172 L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_00789 1.1e-264 npr 1.11.1.1 C NADH oxidase
EMDOCAHE_00790 1e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
EMDOCAHE_00792 4.6e-26 L Helix-turn-helix domain
EMDOCAHE_00793 6.2e-85 L hmm pf00665
EMDOCAHE_00794 2.1e-100 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
EMDOCAHE_00795 7e-153 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
EMDOCAHE_00796 1.6e-144 cylB V ABC-2 type transporter
EMDOCAHE_00797 3e-170 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00798 3.3e-200 L Belongs to the 'phage' integrase family
EMDOCAHE_00799 8.9e-58
EMDOCAHE_00801 3.7e-129 S Domain of unknown function (DUF4393)
EMDOCAHE_00802 2e-23
EMDOCAHE_00803 1.1e-21 E Zn peptidase
EMDOCAHE_00804 9.7e-15 S Protein of unknown function (DUF3644)
EMDOCAHE_00805 2.6e-133 L PFAM transposase, IS4 family protein
EMDOCAHE_00806 6.8e-126 S Protein of unknown function (DUF3644)
EMDOCAHE_00807 5.8e-44 3.4.21.88 K Helix-turn-helix domain
EMDOCAHE_00808 1.1e-15 K Helix-turn-helix XRE-family like proteins
EMDOCAHE_00809 8.9e-147 K Phage regulatory protein
EMDOCAHE_00813 7.2e-10 S Domain of unknown function (DUF771)
EMDOCAHE_00819 3.8e-93 recT L RecT family
EMDOCAHE_00820 1.5e-33 recT L RecT family
EMDOCAHE_00821 4.5e-152 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
EMDOCAHE_00822 2e-94 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EMDOCAHE_00823 1.4e-26 L Psort location Cytoplasmic, score
EMDOCAHE_00826 4.2e-79 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00832 1.1e-09 L Terminase small subunit
EMDOCAHE_00834 9.9e-171 L Integrase core domain
EMDOCAHE_00835 1.9e-46 L Transposase
EMDOCAHE_00837 1.1e-79 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00838 1.9e-224 emrY EGP Major facilitator Superfamily
EMDOCAHE_00839 7.7e-171 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EMDOCAHE_00840 2.7e-188 L PFAM Integrase, catalytic core
EMDOCAHE_00841 3.1e-245 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EMDOCAHE_00842 1.2e-188 L PFAM Integrase, catalytic core
EMDOCAHE_00843 3.8e-85 macB_3 V FtsX-like permease family
EMDOCAHE_00844 2.9e-85 macB_3 V FtsX-like permease family
EMDOCAHE_00845 3.2e-225 L Transposase
EMDOCAHE_00846 9.5e-72 macB_3 V FtsX-like permease family
EMDOCAHE_00847 1.6e-90 S PAS domain
EMDOCAHE_00848 1.1e-228 tnp L MULE transposase domain
EMDOCAHE_00849 2.2e-30 E IrrE N-terminal-like domain
EMDOCAHE_00850 4.8e-86 yrjD S LUD domain
EMDOCAHE_00851 1.4e-244 lutB C 4Fe-4S dicluster domain
EMDOCAHE_00852 5.6e-122 lutA C Cysteine-rich domain
EMDOCAHE_00853 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
EMDOCAHE_00854 4.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EMDOCAHE_00855 2.4e-37 ynzC S UPF0291 protein
EMDOCAHE_00856 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
EMDOCAHE_00857 3.3e-115 plsC 2.3.1.51 I Acyltransferase
EMDOCAHE_00858 1.4e-136 yabB 2.1.1.223 L Methyltransferase small domain
EMDOCAHE_00859 2.3e-47 yazA L GIY-YIG catalytic domain protein
EMDOCAHE_00860 5e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
EMDOCAHE_00861 4.9e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EMDOCAHE_00862 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EMDOCAHE_00863 4.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EMDOCAHE_00864 1.3e-142 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EMDOCAHE_00865 2.3e-134 cdsA 2.7.7.41 I Belongs to the CDS family
EMDOCAHE_00866 3.8e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EMDOCAHE_00867 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EMDOCAHE_00868 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EMDOCAHE_00869 4.1e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
EMDOCAHE_00870 1e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
EMDOCAHE_00871 1.2e-206 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EMDOCAHE_00872 1.1e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EMDOCAHE_00873 2e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EMDOCAHE_00874 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EMDOCAHE_00875 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
EMDOCAHE_00876 3.7e-224 nusA K Participates in both transcription termination and antitermination
EMDOCAHE_00877 1.4e-47 ylxR K Protein of unknown function (DUF448)
EMDOCAHE_00878 3.2e-50 ylxQ J ribosomal protein
EMDOCAHE_00879 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EMDOCAHE_00880 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EMDOCAHE_00881 2e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EMDOCAHE_00882 1.6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EMDOCAHE_00883 1.7e-249 EGP Major facilitator Superfamily
EMDOCAHE_00884 3.1e-58 L Helix-turn-helix domain
EMDOCAHE_00885 4.8e-154 L hmm pf00665
EMDOCAHE_00886 2.2e-81 tlpA2 L Transposase IS200 like
EMDOCAHE_00887 3.4e-56 L transposase, IS605 OrfB family
EMDOCAHE_00888 1.1e-225 L Transposase
EMDOCAHE_00889 1.3e-170 L Integrase core domain
EMDOCAHE_00890 1.9e-46 L Transposase
EMDOCAHE_00891 3.2e-253 G Major Facilitator
EMDOCAHE_00892 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
EMDOCAHE_00893 2.1e-177 K Transcriptional regulator, LacI family
EMDOCAHE_00894 5.4e-157 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
EMDOCAHE_00895 4.6e-09
EMDOCAHE_00896 2.7e-224 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
EMDOCAHE_00898 5.6e-58 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00899 3e-189 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EMDOCAHE_00901 3.2e-79 D Cellulose biosynthesis protein BcsQ
EMDOCAHE_00902 8.2e-61 xerC L Phage integrase, N-terminal SAM-like domain
EMDOCAHE_00903 4.9e-52 ypaA S Protein of unknown function (DUF1304)
EMDOCAHE_00904 5.5e-85 D Alpha beta
EMDOCAHE_00905 2.9e-51 L Helix-turn-helix domain
EMDOCAHE_00906 3.4e-20 L hmm pf00665
EMDOCAHE_00907 9.5e-46 L Transposase
EMDOCAHE_00908 2.9e-170 L Integrase core domain
EMDOCAHE_00909 0.0 uvrA2 L ABC transporter
EMDOCAHE_00910 9.5e-79 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00911 7.1e-186 L PFAM Integrase catalytic region
EMDOCAHE_00912 5.4e-62
EMDOCAHE_00913 1.3e-190 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EMDOCAHE_00914 2.2e-57 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EMDOCAHE_00915 0.0 dnaK O Heat shock 70 kDa protein
EMDOCAHE_00916 1.1e-177 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EMDOCAHE_00917 2.4e-50 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EMDOCAHE_00918 7.8e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EMDOCAHE_00919 1.6e-103 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EMDOCAHE_00920 4.2e-55 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EMDOCAHE_00921 9.9e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
EMDOCAHE_00922 2.8e-199 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EMDOCAHE_00923 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EMDOCAHE_00924 3.3e-09
EMDOCAHE_00925 5.7e-112 3.1.3.73 G phosphoglycerate mutase
EMDOCAHE_00926 3.5e-111 C aldo keto reductase
EMDOCAHE_00927 8.3e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EMDOCAHE_00928 4.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMDOCAHE_00929 7.1e-269 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
EMDOCAHE_00930 1.8e-78 K 2 iron, 2 sulfur cluster binding
EMDOCAHE_00931 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EMDOCAHE_00932 1.2e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
EMDOCAHE_00933 9.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
EMDOCAHE_00934 1e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EMDOCAHE_00935 7.2e-54 C FMN binding
EMDOCAHE_00936 6.8e-62 T His Kinase A (phosphoacceptor) domain
EMDOCAHE_00937 1e-48 T Transcriptional regulatory protein, C terminal
EMDOCAHE_00938 6.8e-16 S ABC-type transport system involved in multi-copper enzyme maturation permease component
EMDOCAHE_00939 9e-220 iscS 2.8.1.7 E Aminotransferase class V
EMDOCAHE_00941 8.4e-81 tlpA2 L Transposase IS200 like
EMDOCAHE_00942 2.1e-238 L transposase, IS605 OrfB family
EMDOCAHE_00943 5.7e-101 P Cadmium resistance transporter
EMDOCAHE_00944 3.2e-116 S Protein of unknown function (DUF554)
EMDOCAHE_00945 1.2e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EMDOCAHE_00946 1.1e-158 P Belongs to the nlpA lipoprotein family
EMDOCAHE_00947 8.7e-98 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EMDOCAHE_00948 1.2e-36 V CAAX protease self-immunity
EMDOCAHE_00949 8.6e-67 psiE S Phosphate-starvation-inducible E
EMDOCAHE_00950 7.6e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EMDOCAHE_00951 4.5e-112 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EMDOCAHE_00952 2.7e-143 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EMDOCAHE_00953 1.9e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EMDOCAHE_00954 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EMDOCAHE_00955 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EMDOCAHE_00956 7.7e-94 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EMDOCAHE_00957 8.4e-35 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EMDOCAHE_00958 5.5e-36 S CRISPR-associated protein (Cas_Csn2)
EMDOCAHE_00960 9.6e-34 aes I Hydrolase, alpha beta domain protein
EMDOCAHE_00961 1.8e-34 aes I Carboxylesterase family
EMDOCAHE_00963 1.7e-98 S integral membrane protein
EMDOCAHE_00964 6.2e-103 L Probable transposase
EMDOCAHE_00965 5.5e-172 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_00966 7.4e-104 L Probable transposase
EMDOCAHE_00967 5.2e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EMDOCAHE_00969 1.2e-54
EMDOCAHE_00970 1.8e-181 prmA J Ribosomal protein L11 methyltransferase
EMDOCAHE_00971 5.2e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EMDOCAHE_00972 4.4e-58
EMDOCAHE_00973 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EMDOCAHE_00974 2.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EMDOCAHE_00975 3.5e-85 slyA K Transcriptional regulator
EMDOCAHE_00976 2.7e-219 metC1 2.5.1.48, 4.4.1.8 E cystathionine
EMDOCAHE_00977 3.3e-211 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
EMDOCAHE_00978 3.1e-67 yxeM ET Bacterial periplasmic substrate-binding proteins
EMDOCAHE_00979 4.1e-47 yxeL K acetyltransferase
EMDOCAHE_00980 2.2e-70 yxeN U ABC transporter, permease protein
EMDOCAHE_00981 3.4e-78 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
EMDOCAHE_00982 1.7e-146 3.5.1.47 E Peptidase dimerisation domain
EMDOCAHE_00983 1.9e-171 pcaB 4.3.2.2 F Adenylosuccinate lyase C-terminus
EMDOCAHE_00984 3.3e-90 yxeQ S MmgE/PrpD family
EMDOCAHE_00986 5.4e-113 papP P ABC transporter, permease protein
EMDOCAHE_00987 1.9e-89 P ABC transporter permease
EMDOCAHE_00988 8.7e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EMDOCAHE_00989 6.9e-153 cjaA ET ABC transporter substrate-binding protein
EMDOCAHE_00990 2.7e-137 IQ KR domain
EMDOCAHE_00992 6.6e-193 hom1 1.1.1.3 E Homoserine dehydrogenase
EMDOCAHE_00993 6.3e-159 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
EMDOCAHE_00994 5.8e-245 mmuP E amino acid
EMDOCAHE_00995 3.9e-173 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
EMDOCAHE_00996 1.4e-169 yniA G Phosphotransferase enzyme family
EMDOCAHE_00997 1.4e-173 lytH 3.5.1.28 M Ami_3
EMDOCAHE_00998 8e-196 6.3.1.20 H Lipoate-protein ligase
EMDOCAHE_00999 1e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
EMDOCAHE_01000 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EMDOCAHE_01001 5.1e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
EMDOCAHE_01002 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EMDOCAHE_01003 4.6e-71 yqeY S YqeY-like protein
EMDOCAHE_01004 1.1e-178 phoH T phosphate starvation-inducible protein PhoH
EMDOCAHE_01005 1.5e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EMDOCAHE_01006 2.3e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EMDOCAHE_01007 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EMDOCAHE_01008 2.9e-156 recO L Involved in DNA repair and RecF pathway recombination
EMDOCAHE_01009 4.9e-187 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EMDOCAHE_01010 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EMDOCAHE_01011 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EMDOCAHE_01012 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EMDOCAHE_01013 4.3e-155 L COG2801 Transposase and inactivated derivatives
EMDOCAHE_01014 1.3e-38 L Transposase and inactivated derivatives
EMDOCAHE_01015 2.2e-86
EMDOCAHE_01016 1e-69 S Asp23 family, cell envelope-related function
EMDOCAHE_01017 6e-12 S Transglycosylase associated protein
EMDOCAHE_01018 3.8e-16
EMDOCAHE_01019 6.6e-114 L PFAM Integrase, catalytic core
EMDOCAHE_01020 1.1e-247 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EMDOCAHE_01021 1.1e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EMDOCAHE_01022 1.5e-178 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EMDOCAHE_01023 6.5e-262 lysC 2.7.2.4 E Belongs to the aspartokinase family
EMDOCAHE_01024 2.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EMDOCAHE_01025 2.9e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EMDOCAHE_01026 4.7e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EMDOCAHE_01027 9.2e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EMDOCAHE_01028 8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EMDOCAHE_01029 2.9e-218 patA 2.6.1.1 E Aminotransferase
EMDOCAHE_01030 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EMDOCAHE_01031 6.7e-227 ktrB P Potassium uptake protein
EMDOCAHE_01032 7.5e-118 ktrA P domain protein
EMDOCAHE_01033 1.2e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
EMDOCAHE_01034 1.7e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EMDOCAHE_01035 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EMDOCAHE_01037 0.0 dnaE 2.7.7.7 L DNA polymerase
EMDOCAHE_01038 2.4e-267 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EMDOCAHE_01039 1.8e-167 cvfB S S1 domain
EMDOCAHE_01040 2.4e-132 xerD D recombinase XerD
EMDOCAHE_01041 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EMDOCAHE_01042 3.9e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EMDOCAHE_01043 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EMDOCAHE_01044 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EMDOCAHE_01045 4.8e-81 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EMDOCAHE_01046 1.3e-198 ypbB 5.1.3.1 S Helix-turn-helix domain
EMDOCAHE_01047 3.1e-278 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
EMDOCAHE_01048 9.7e-31 M Lysin motif
EMDOCAHE_01049 5.8e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EMDOCAHE_01050 5.8e-209 rpsA 1.17.7.4 J Ribosomal protein S1
EMDOCAHE_01051 1.7e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EMDOCAHE_01052 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EMDOCAHE_01053 1.8e-234 S Tetratricopeptide repeat protein
EMDOCAHE_01054 4.7e-165 xerD L Phage integrase, N-terminal SAM-like domain
EMDOCAHE_01055 2.4e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EMDOCAHE_01056 0.0 yfmR S ABC transporter, ATP-binding protein
EMDOCAHE_01057 2.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EMDOCAHE_01058 8.7e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EMDOCAHE_01059 1.2e-109 hlyIII S protein, hemolysin III
EMDOCAHE_01060 2.4e-153 DegV S EDD domain protein, DegV family
EMDOCAHE_01061 2.9e-218 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
EMDOCAHE_01062 3.2e-107 cat S Bacterial transferase hexapeptide (six repeats)
EMDOCAHE_01063 1.1e-167 ypmR E lipolytic protein G-D-S-L family
EMDOCAHE_01064 7.1e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
EMDOCAHE_01065 3.1e-36 yozE S Belongs to the UPF0346 family
EMDOCAHE_01066 1.1e-225 L Transposase
EMDOCAHE_01067 1.2e-61 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
EMDOCAHE_01068 1.3e-60 arsD S Arsenical resistance operon trans-acting repressor ArsD
EMDOCAHE_01069 8.5e-229 tnp L MULE transposase domain
EMDOCAHE_01070 0.0 arsA 3.6.3.16 D Anion-transporting ATPase
EMDOCAHE_01071 5.8e-217 arsB U Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EMDOCAHE_01072 8.5e-229 tnp L MULE transposase domain
EMDOCAHE_01073 3.2e-62 K Transcriptional regulator
EMDOCAHE_01074 3.4e-101 cadD P Cadmium resistance transporter
EMDOCAHE_01075 2.2e-30 K Cro/C1-type HTH DNA-binding domain
EMDOCAHE_01076 3.1e-82 nicK L Psort location Cytoplasmic, score 8.87
EMDOCAHE_01077 2.2e-22
EMDOCAHE_01078 6.3e-102 L DNA integration
EMDOCAHE_01079 1.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EMDOCAHE_01080 2e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EMDOCAHE_01081 1.4e-164 dprA LU DNA protecting protein DprA
EMDOCAHE_01082 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EMDOCAHE_01083 1.2e-154 D DNA integration
EMDOCAHE_01084 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
EMDOCAHE_01085 2.8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EMDOCAHE_01086 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EMDOCAHE_01087 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EMDOCAHE_01088 5.2e-95 S Protein of unknown function (DUF1440)
EMDOCAHE_01089 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
EMDOCAHE_01090 2.3e-71 yqkB S Belongs to the HesB IscA family
EMDOCAHE_01091 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
EMDOCAHE_01092 5.7e-94 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
EMDOCAHE_01093 2.2e-81 yebR 1.8.4.14 T GAF domain-containing protein
EMDOCAHE_01094 4.7e-244 U Belongs to the purine-cytosine permease (2.A.39) family
EMDOCAHE_01095 4e-242 codA 3.5.4.1 F cytosine deaminase
EMDOCAHE_01096 0.0 oppD EP Psort location Cytoplasmic, score
EMDOCAHE_01098 2.6e-255 rarA L recombination factor protein RarA
EMDOCAHE_01099 4.4e-118 S Protein of unknown function (DUF554)
EMDOCAHE_01100 9.3e-245 yhjX P Major Facilitator Superfamily
EMDOCAHE_01101 6.5e-18 lmrB EGP Major facilitator Superfamily
EMDOCAHE_01102 1.4e-51 clcA P chloride
EMDOCAHE_01103 5.5e-11 clcA P chloride
EMDOCAHE_01104 1e-157 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
EMDOCAHE_01105 4.2e-117 5.1.1.13 M racemase activity, acting on amino acids and derivatives
EMDOCAHE_01106 7.8e-261 arcD E Amino acid permease
EMDOCAHE_01107 1.7e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EMDOCAHE_01108 2.6e-104 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
EMDOCAHE_01109 4.4e-71 yncA 2.3.1.79 S Maltose acetyltransferase
EMDOCAHE_01110 2.8e-74 S Fic/DOC family
EMDOCAHE_01112 5.5e-128 L PFAM transposase, IS4 family protein
EMDOCAHE_01113 3.2e-214 tra L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_01114 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
EMDOCAHE_01115 1.6e-219 EGP Sugar (and other) transporter
EMDOCAHE_01116 4.3e-184 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
EMDOCAHE_01117 3.4e-216 2.6.1.1 E Aminotransferase
EMDOCAHE_01120 4.9e-125 S Phage minor capsid protein 2
EMDOCAHE_01121 1.1e-163 I alpha/beta hydrolase fold
EMDOCAHE_01122 1.4e-95 K Acetyltransferase (GNAT) domain
EMDOCAHE_01125 1.7e-160 S DUF218 domain
EMDOCAHE_01126 5.1e-167 1.1.1.346 C Aldo keto reductase
EMDOCAHE_01127 1.3e-79 hmpT S ECF-type riboflavin transporter, S component
EMDOCAHE_01128 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
EMDOCAHE_01129 9.6e-236 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
EMDOCAHE_01130 3.1e-62 ywkB S Membrane transport protein
EMDOCAHE_01131 7.1e-203 xerS L Belongs to the 'phage' integrase family
EMDOCAHE_01132 3.2e-180 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EMDOCAHE_01133 7.9e-224 4.4.1.8 E Aminotransferase, class I
EMDOCAHE_01134 8.4e-226 L transposase, IS605 OrfB family
EMDOCAHE_01135 4.1e-195 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
EMDOCAHE_01136 1.4e-181 C Zinc-binding dehydrogenase
EMDOCAHE_01137 3.1e-102 proW P ABC transporter, permease protein
EMDOCAHE_01138 4.6e-140 proV E ABC transporter, ATP-binding protein
EMDOCAHE_01139 1.8e-108 proWZ P ABC transporter permease
EMDOCAHE_01140 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
EMDOCAHE_01141 1.5e-55 K Transcriptional regulator
EMDOCAHE_01142 4.2e-74 O OsmC-like protein
EMDOCAHE_01143 2e-73 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
EMDOCAHE_01144 1.4e-22 EGP Major Facilitator Superfamily
EMDOCAHE_01145 1.8e-102 L Probable transposase
EMDOCAHE_01146 4.2e-225 L Transposase
EMDOCAHE_01147 4.1e-41 L Probable transposase
EMDOCAHE_01148 3e-28 EGP Major Facilitator Superfamily
EMDOCAHE_01149 1.6e-44 EGP Major Facilitator Superfamily
EMDOCAHE_01150 1.6e-69 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
EMDOCAHE_01151 1.3e-56 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
EMDOCAHE_01152 3.5e-15 C Flavodoxin
EMDOCAHE_01153 4.3e-27 GM NmrA-like family
EMDOCAHE_01154 6.6e-19 S NAD(P)H dehydrogenase (quinone) activity
EMDOCAHE_01155 1.1e-247 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EMDOCAHE_01156 1.2e-27 glcU U sugar transport
EMDOCAHE_01157 5.5e-228 tnp L MULE transposase domain
EMDOCAHE_01158 7.4e-45 glcU U sugar transport
EMDOCAHE_01159 3.5e-87 galR K Transcriptional regulator
EMDOCAHE_01160 1.1e-166 L PFAM Integrase catalytic region
EMDOCAHE_01161 3.2e-23 L Helix-turn-helix domain
EMDOCAHE_01162 1.8e-36 L Helix-turn-helix domain
EMDOCAHE_01163 1.6e-227 tnp L MULE transposase domain
EMDOCAHE_01164 4.3e-38 M Protein of unknown function (DUF3737)
EMDOCAHE_01165 2.5e-121 L hmm pf00665
EMDOCAHE_01166 2.7e-171 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_01167 6.7e-107 L Integrase
EMDOCAHE_01168 4e-70 ydjP I Alpha/beta hydrolase family
EMDOCAHE_01169 6.7e-49 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
EMDOCAHE_01170 6.7e-66 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
EMDOCAHE_01171 9e-40 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
EMDOCAHE_01173 1.9e-46 L Transposase
EMDOCAHE_01174 4.7e-41 L Integrase core domain
EMDOCAHE_01175 3.9e-159 tnp L MULE transposase domain
EMDOCAHE_01176 5.5e-57 ydiI Q Thioesterase superfamily
EMDOCAHE_01177 5.3e-158 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EMDOCAHE_01178 1.3e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EMDOCAHE_01179 1.7e-218 G Transporter, major facilitator family protein
EMDOCAHE_01180 4.7e-207 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
EMDOCAHE_01181 1.5e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EMDOCAHE_01182 1.3e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EMDOCAHE_01183 2.5e-40 gcvR T Belongs to the UPF0237 family
EMDOCAHE_01184 1.3e-243 XK27_08635 S UPF0210 protein
EMDOCAHE_01185 2.8e-179 yobV1 K WYL domain
EMDOCAHE_01186 4.1e-68 S pyridoxamine 5-phosphate
EMDOCAHE_01187 1.1e-29
EMDOCAHE_01189 4.8e-190 L Helix-turn-helix domain
EMDOCAHE_01191 3.3e-64
EMDOCAHE_01192 1.3e-112 yicL EG EamA-like transporter family
EMDOCAHE_01193 1.3e-73 S Domain of unknown function (DUF4352)
EMDOCAHE_01194 0.0 1.3.5.4 C FAD binding domain
EMDOCAHE_01195 4.4e-169 K LysR substrate binding domain
EMDOCAHE_01196 4.1e-161 rssA S Phospholipase, patatin family
EMDOCAHE_01197 7.4e-214 phbA 2.3.1.9 I Belongs to the thiolase family
EMDOCAHE_01198 4.7e-178 S AI-2E family transporter
EMDOCAHE_01199 2.9e-123 S membrane transporter protein
EMDOCAHE_01200 1.4e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
EMDOCAHE_01201 3.4e-194 V Beta-lactamase
EMDOCAHE_01202 9.2e-228
EMDOCAHE_01204 6.3e-154 S Alpha/beta hydrolase of unknown function (DUF915)
EMDOCAHE_01205 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EMDOCAHE_01206 2.2e-165 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
EMDOCAHE_01207 1.2e-163 endA F DNA RNA non-specific endonuclease
EMDOCAHE_01208 2.7e-268 pipD E Dipeptidase
EMDOCAHE_01210 1.4e-189 L Helix-turn-helix domain
EMDOCAHE_01211 2.3e-254 yifK E Amino acid permease
EMDOCAHE_01213 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EMDOCAHE_01214 1.7e-237 N Uncharacterized conserved protein (DUF2075)
EMDOCAHE_01215 4.1e-55 S SNARE associated Golgi protein
EMDOCAHE_01216 7.1e-186 L PFAM Integrase catalytic region
EMDOCAHE_01217 2.2e-78 ndk 2.7.4.6 F Belongs to the NDK family
EMDOCAHE_01218 4.1e-98 padR K Virulence activator alpha C-term
EMDOCAHE_01219 1.4e-93 padC Q Phenolic acid decarboxylase
EMDOCAHE_01221 9.5e-219 I transferase activity, transferring acyl groups other than amino-acyl groups
EMDOCAHE_01223 6.3e-143 ET Bacterial periplasmic substrate-binding proteins
EMDOCAHE_01224 2.6e-157 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
EMDOCAHE_01225 1.5e-225 aadAT EK Aminotransferase, class I
EMDOCAHE_01226 3e-259 guaD 3.5.4.3 F Amidohydrolase family
EMDOCAHE_01227 4.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
EMDOCAHE_01230 2.9e-56 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
EMDOCAHE_01231 5.2e-74 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EMDOCAHE_01232 3.6e-49 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
EMDOCAHE_01233 1.9e-46 L Transposase
EMDOCAHE_01234 1.3e-170 L Integrase core domain
EMDOCAHE_01235 2e-61 rmeB K transcriptional regulator, MerR family
EMDOCAHE_01236 2.5e-133 ybbM S Uncharacterised protein family (UPF0014)
EMDOCAHE_01237 3.1e-41 ybbL S ABC transporter, ATP-binding protein
EMDOCAHE_01238 5.8e-58 ybbL S ABC transporter, ATP-binding protein
EMDOCAHE_01239 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EMDOCAHE_01240 0.0 N Uncharacterized conserved protein (DUF2075)
EMDOCAHE_01242 2.4e-101 K DNA-templated transcription, initiation
EMDOCAHE_01243 6.2e-85 L hmm pf00665
EMDOCAHE_01244 8.3e-51 L Helix-turn-helix domain
EMDOCAHE_01245 1.2e-73 IQ reductase
EMDOCAHE_01246 2e-240 treB G phosphotransferase system
EMDOCAHE_01247 1.5e-71 treR K UTRA
EMDOCAHE_01248 3.2e-239 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
EMDOCAHE_01249 5.9e-52 L hmm pf00665
EMDOCAHE_01252 2.9e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EMDOCAHE_01253 2.2e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EMDOCAHE_01254 4.9e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EMDOCAHE_01255 1.1e-103 wecD3 K Acetyltransferase (GNAT) family
EMDOCAHE_01256 7.3e-164 ubiB S ABC1 family
EMDOCAHE_01257 7.6e-127 ubiB S ABC1 family
EMDOCAHE_01258 2.3e-130 1.14.12.17 C Oxidoreductase NAD-binding domain
EMDOCAHE_01259 2.6e-169 GK ROK family
EMDOCAHE_01260 3.7e-39
EMDOCAHE_01261 2.3e-78 copY K Copper transport repressor CopY TcrY
EMDOCAHE_01263 1.8e-151 L Belongs to the 'phage' integrase family
EMDOCAHE_01264 1.9e-46 L Transposase
EMDOCAHE_01265 5.9e-117 L Integrase core domain
EMDOCAHE_01266 1.3e-38 L Transposase and inactivated derivatives
EMDOCAHE_01267 4.3e-155 L COG2801 Transposase and inactivated derivatives
EMDOCAHE_01268 7.2e-169 G Belongs to the carbohydrate kinase PfkB family
EMDOCAHE_01269 2.3e-251 F Belongs to the purine-cytosine permease (2.A.39) family
EMDOCAHE_01270 2.4e-192 yegU O ADP-ribosylglycohydrolase
EMDOCAHE_01271 1.6e-76 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
EMDOCAHE_01272 3.6e-08 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EMDOCAHE_01273 6.2e-171 mutR K Transcriptional activator, Rgg GadR MutR family
EMDOCAHE_01274 3.2e-286 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
EMDOCAHE_01275 3.2e-229 gntT EG Gluconate
EMDOCAHE_01276 1.4e-181 K Transcriptional regulator, LacI family
EMDOCAHE_01277 9.5e-61 yneR
EMDOCAHE_01278 9.8e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EMDOCAHE_01279 2.2e-96 V VanZ like family
EMDOCAHE_01280 1.9e-291 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
EMDOCAHE_01281 8.3e-50 ywnB S NAD(P)H-binding
EMDOCAHE_01282 5.3e-35 yjcE P Sodium proton antiporter
EMDOCAHE_01283 5.9e-76
EMDOCAHE_01284 4.3e-183
EMDOCAHE_01285 1.8e-127 narI 1.7.5.1 C Nitrate reductase
EMDOCAHE_01286 3.1e-102 narJ C Nitrate reductase delta subunit
EMDOCAHE_01287 0.0 narH 1.7.5.1 C Respiratory nitrate reductase beta C-terminal
EMDOCAHE_01288 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EMDOCAHE_01289 1.4e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
EMDOCAHE_01290 1.9e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
EMDOCAHE_01291 4.1e-231 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
EMDOCAHE_01292 9.3e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EMDOCAHE_01293 1.1e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EMDOCAHE_01294 4.2e-40
EMDOCAHE_01295 1.4e-77 nreA T GAF domain
EMDOCAHE_01296 8.2e-163 comP 2.7.13.3 F Sensor histidine kinase
EMDOCAHE_01297 4e-116 nreC K PFAM regulatory protein LuxR
EMDOCAHE_01298 1.2e-39
EMDOCAHE_01299 5.7e-183
EMDOCAHE_01300 2e-169 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
EMDOCAHE_01302 3e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EMDOCAHE_01303 1e-162 hipB K Helix-turn-helix
EMDOCAHE_01304 1.5e-58 yitW S Iron-sulfur cluster assembly protein
EMDOCAHE_01305 3.1e-215 narK P Major Facilitator Superfamily
EMDOCAHE_01306 1e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EMDOCAHE_01307 6.4e-35 moaD 2.8.1.12 H ThiS family
EMDOCAHE_01308 2.2e-72 moaE 2.8.1.12 H MoaE protein
EMDOCAHE_01309 2.4e-56 S Flavodoxin
EMDOCAHE_01310 1.5e-170 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EMDOCAHE_01311 5.9e-143 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
EMDOCAHE_01312 2e-230 ndh 1.6.99.3 C NADH dehydrogenase
EMDOCAHE_01313 8e-54 yitW S Iron-sulfur cluster assembly protein
EMDOCAHE_01314 4.7e-19 M1-755 S Domain of unknown function (DUF1858)
EMDOCAHE_01315 4.3e-258 XK27_04775 S PAS domain
EMDOCAHE_01316 2.4e-142 EG EamA-like transporter family
EMDOCAHE_01317 1.2e-188 L PFAM Integrase, catalytic core
EMDOCAHE_01318 6.1e-183 fecB P Periplasmic binding protein
EMDOCAHE_01319 4.2e-272 sufB O assembly protein SufB
EMDOCAHE_01320 3.2e-83 nifU C SUF system FeS assembly protein, NifU family
EMDOCAHE_01321 8.9e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EMDOCAHE_01322 1.7e-243 sufD O FeS assembly protein SufD
EMDOCAHE_01323 8.5e-145 sufC O FeS assembly ATPase SufC
EMDOCAHE_01324 1.4e-33 feoA P FeoA domain
EMDOCAHE_01325 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
EMDOCAHE_01326 6.7e-23 S Virus attachment protein p12 family
EMDOCAHE_01327 2.4e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
EMDOCAHE_01328 2.7e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EMDOCAHE_01329 2.5e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMDOCAHE_01330 7.1e-217 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
EMDOCAHE_01331 8.7e-90 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EMDOCAHE_01332 1.5e-197 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EMDOCAHE_01333 1.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EMDOCAHE_01334 1.2e-102
EMDOCAHE_01335 6.7e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EMDOCAHE_01336 7.6e-13 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
EMDOCAHE_01337 6.4e-213 ydiN G Major Facilitator Superfamily
EMDOCAHE_01339 5.1e-244 dtpT U amino acid peptide transporter
EMDOCAHE_01342 6.6e-153 S Sucrose-6F-phosphate phosphohydrolase
EMDOCAHE_01343 2.4e-44 1.6.5.2 GM NAD(P)H-binding
EMDOCAHE_01344 1.3e-90 1.6.5.2 GM NAD(P)H-binding
EMDOCAHE_01345 1.8e-156 S Alpha beta hydrolase
EMDOCAHE_01346 1.2e-237 lmrB EGP Major facilitator Superfamily
EMDOCAHE_01348 0.0 S Bacterial membrane protein YfhO
EMDOCAHE_01349 6e-49
EMDOCAHE_01350 0.0 kup P Transport of potassium into the cell
EMDOCAHE_01352 8.8e-284 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EMDOCAHE_01353 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EMDOCAHE_01354 0.0 yjbQ P TrkA C-terminal domain protein
EMDOCAHE_01355 1.1e-275 pipD E Dipeptidase
EMDOCAHE_01356 3.4e-158 S Alpha/beta hydrolase of unknown function (DUF915)
EMDOCAHE_01357 8.8e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EMDOCAHE_01358 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EMDOCAHE_01359 1.6e-168 T Calcineurin-like phosphoesterase superfamily domain
EMDOCAHE_01360 1.2e-159 EGP Major facilitator Superfamily
EMDOCAHE_01361 3.4e-201 mdtG EGP Major facilitator Superfamily
EMDOCAHE_01362 1.3e-249 yhdP S Transporter associated domain
EMDOCAHE_01363 1.7e-213 naiP EGP Major facilitator Superfamily
EMDOCAHE_01364 1.7e-15 K LysR substrate binding domain protein
EMDOCAHE_01365 7.2e-52 K Transcriptional regulator
EMDOCAHE_01366 6.8e-217 E GDSL-like Lipase/Acylhydrolase family
EMDOCAHE_01367 4e-245 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EMDOCAHE_01368 1.2e-194 lplA 6.3.1.20 H Lipoate-protein ligase
EMDOCAHE_01369 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
EMDOCAHE_01370 1.2e-199 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EMDOCAHE_01371 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
EMDOCAHE_01372 1.4e-182 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EMDOCAHE_01373 8.5e-229 tnp L MULE transposase domain
EMDOCAHE_01374 1.1e-09 yphJ 4.1.1.44 S decarboxylase
EMDOCAHE_01375 1.6e-31 yphJ 4.1.1.44 S decarboxylase
EMDOCAHE_01376 2.8e-54 azlD E Branched-chain amino acid transport
EMDOCAHE_01377 7e-91 azlC E azaleucine resistance protein AzlC
EMDOCAHE_01378 1.9e-286 thrC 4.2.3.1 E Threonine synthase
EMDOCAHE_01379 3.5e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EMDOCAHE_01380 8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EMDOCAHE_01381 3.5e-99 K Acetyltransferase (GNAT) domain
EMDOCAHE_01382 2.6e-112 ylbE GM NAD(P)H-binding
EMDOCAHE_01383 1.5e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
EMDOCAHE_01384 1.2e-132 S Belongs to the UPF0246 family
EMDOCAHE_01385 4.6e-98
EMDOCAHE_01386 3.2e-161 degV S EDD domain protein, DegV family
EMDOCAHE_01387 0.0 FbpA K Fibronectin-binding protein
EMDOCAHE_01388 2.1e-238 L transposase, IS605 OrfB family
EMDOCAHE_01389 8.3e-13 tlpA2 L Transposase IS200 like
EMDOCAHE_01390 2.4e-217 L Transposase
EMDOCAHE_01391 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
EMDOCAHE_01392 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EMDOCAHE_01393 1.8e-206 carA 6.3.5.5 F Belongs to the CarA family
EMDOCAHE_01394 3.4e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EMDOCAHE_01395 1.1e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EMDOCAHE_01396 1.9e-69 esbA S Family of unknown function (DUF5322)
EMDOCAHE_01397 3.1e-71 rnhA 3.1.26.4 L Ribonuclease HI
EMDOCAHE_01398 8.7e-110 XK27_02070 S Nitroreductase family
EMDOCAHE_01399 4e-156 yckB ET Belongs to the bacterial solute-binding protein 3 family
EMDOCAHE_01400 1.2e-118 yecS E ABC transporter permease
EMDOCAHE_01401 9.3e-21 M Glycosyltransferase like family 2
EMDOCAHE_01402 1.9e-46 L Transposase
EMDOCAHE_01403 7.2e-109 L Integrase core domain
EMDOCAHE_01405 1.1e-267 nylA 3.5.1.4 J Belongs to the amidase family
EMDOCAHE_01406 1.7e-27 arcD S C4-dicarboxylate anaerobic carrier
EMDOCAHE_01407 5.5e-88 arcD S C4-dicarboxylate anaerobic carrier
EMDOCAHE_01408 1.9e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EMDOCAHE_01409 8.9e-83 F Hydrolase, NUDIX family
EMDOCAHE_01410 1.4e-212 S Type IV secretion-system coupling protein DNA-binding domain
EMDOCAHE_01411 0.0 tetP J elongation factor G
EMDOCAHE_01412 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EMDOCAHE_01413 3.9e-110 ypsA S Belongs to the UPF0398 family
EMDOCAHE_01414 1e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EMDOCAHE_01415 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
EMDOCAHE_01416 3.7e-160 EG EamA-like transporter family
EMDOCAHE_01417 1.8e-192 C Aldo keto reductase family protein
EMDOCAHE_01418 1.3e-121 ypuA S Protein of unknown function (DUF1002)
EMDOCAHE_01419 8e-134 dnaD L DnaD domain protein
EMDOCAHE_01420 2.1e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
EMDOCAHE_01421 1.6e-88 ypmB S Protein conserved in bacteria
EMDOCAHE_01422 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EMDOCAHE_01423 2.2e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EMDOCAHE_01424 5.3e-181 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EMDOCAHE_01425 1.5e-211 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
EMDOCAHE_01426 1.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EMDOCAHE_01427 2.9e-94 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_01428 5.4e-239 L transposase, IS605 OrfB family
EMDOCAHE_01429 1.5e-72 tlpA2 L Transposase IS200 like
EMDOCAHE_01430 5.3e-272 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EMDOCAHE_01431 4.2e-152 yitU 3.1.3.104 S hydrolase
EMDOCAHE_01432 2.9e-74 K FR47-like protein
EMDOCAHE_01433 1.3e-73 tnpR L Resolvase, N terminal domain
EMDOCAHE_01434 6.9e-118 L Integrase core domain
EMDOCAHE_01435 1.2e-41 L Integrase core domain
EMDOCAHE_01436 9.5e-46 L Transposase
EMDOCAHE_01437 4.3e-80 L hmm pf00665
EMDOCAHE_01438 1.9e-58 L hmm pf00665
EMDOCAHE_01439 2.1e-47 L Helix-turn-helix domain
EMDOCAHE_01440 2.3e-162 L hmm pf00665
EMDOCAHE_01441 3.1e-185 ybiR P Citrate transporter
EMDOCAHE_01442 1.5e-149 L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_01443 5.5e-228 tnp L MULE transposase domain
EMDOCAHE_01444 5.9e-76 L PFAM Integrase catalytic region
EMDOCAHE_01445 4e-32 L PFAM Integrase catalytic region
EMDOCAHE_01447 6.6e-79 tnp L MULE transposase domain
EMDOCAHE_01448 3.8e-215 tra L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_01449 1.7e-80 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_01450 1.4e-288 mycA 4.2.1.53 S MCRA family
EMDOCAHE_01452 2.6e-255 gor 1.8.1.7 C Glutathione reductase
EMDOCAHE_01453 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EMDOCAHE_01454 8.6e-58 L hmm pf00665
EMDOCAHE_01455 2.5e-214 tra L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_01456 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EMDOCAHE_01457 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EMDOCAHE_01458 2.5e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EMDOCAHE_01459 8.9e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EMDOCAHE_01460 1.8e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EMDOCAHE_01461 7.7e-114 ycsI S Protein of unknown function (DUF1445)
EMDOCAHE_01463 8.2e-123 L PFAM transposase, IS4 family protein
EMDOCAHE_01464 2.6e-140 L PFAM Integrase catalytic region
EMDOCAHE_01467 2.4e-17 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EMDOCAHE_01472 2.6e-193 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
EMDOCAHE_01473 1.4e-37 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
EMDOCAHE_01474 1.5e-71 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EMDOCAHE_01475 1.9e-187 P Sodium:sulfate symporter transmembrane region
EMDOCAHE_01476 3.7e-72 K LysR substrate binding domain
EMDOCAHE_01477 2.8e-38
EMDOCAHE_01480 9.9e-32
EMDOCAHE_01481 3.6e-80 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
EMDOCAHE_01482 3.2e-127 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EMDOCAHE_01483 1.8e-71 casE S CRISPR_assoc
EMDOCAHE_01484 2.2e-67 casD S CRISPR-associated protein (Cas_Cas5)
EMDOCAHE_01485 4.8e-130 casC L CT1975-like protein
EMDOCAHE_01486 1.9e-40 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
EMDOCAHE_01487 1.2e-145 casA L the current gene model (or a revised gene model) may contain a frame shift
EMDOCAHE_01488 5.1e-298 cas3 L CRISPR-associated helicase cas3
EMDOCAHE_01489 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EMDOCAHE_01490 7.5e-261 yfnA E Amino Acid
EMDOCAHE_01491 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EMDOCAHE_01492 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EMDOCAHE_01493 5.4e-40 ylqC S Belongs to the UPF0109 family
EMDOCAHE_01494 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EMDOCAHE_01495 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
EMDOCAHE_01496 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EMDOCAHE_01497 5.5e-153 pstA P Phosphate transport system permease protein PstA
EMDOCAHE_01498 5.6e-153 pstC P probably responsible for the translocation of the substrate across the membrane
EMDOCAHE_01499 1.6e-157 pstS P Phosphate
EMDOCAHE_01500 2.9e-128 K Transcriptional regulatory protein, C-terminal domain protein
EMDOCAHE_01501 9.4e-32
EMDOCAHE_01502 4.4e-29
EMDOCAHE_01504 2.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EMDOCAHE_01505 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EMDOCAHE_01506 1.5e-198 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EMDOCAHE_01507 0.0 smc D Required for chromosome condensation and partitioning
EMDOCAHE_01508 2e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EMDOCAHE_01509 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EMDOCAHE_01510 2.8e-164 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EMDOCAHE_01511 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EMDOCAHE_01512 5e-304 yloV S DAK2 domain fusion protein YloV
EMDOCAHE_01513 3.6e-58 asp S Asp23 family, cell envelope-related function
EMDOCAHE_01514 7.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EMDOCAHE_01515 4.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
EMDOCAHE_01516 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EMDOCAHE_01517 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EMDOCAHE_01518 0.0 KLT serine threonine protein kinase
EMDOCAHE_01519 2.2e-131 stp 3.1.3.16 T phosphatase
EMDOCAHE_01520 1e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EMDOCAHE_01521 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EMDOCAHE_01522 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EMDOCAHE_01523 1.8e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EMDOCAHE_01524 3.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EMDOCAHE_01525 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EMDOCAHE_01526 2.5e-15
EMDOCAHE_01527 7e-306 recN L May be involved in recombinational repair of damaged DNA
EMDOCAHE_01528 6.2e-76 argR K Regulates arginine biosynthesis genes
EMDOCAHE_01529 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EMDOCAHE_01530 9.6e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EMDOCAHE_01531 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EMDOCAHE_01532 1.5e-256 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EMDOCAHE_01533 2.6e-160 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EMDOCAHE_01534 4e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EMDOCAHE_01535 4.1e-72 yqhY S Asp23 family, cell envelope-related function
EMDOCAHE_01536 8.1e-207 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
EMDOCAHE_01537 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EMDOCAHE_01538 9e-53 ysxB J Cysteine protease Prp
EMDOCAHE_01539 1.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
EMDOCAHE_01540 9.6e-115 K Transcriptional regulator
EMDOCAHE_01542 1.9e-92 dut S Protein conserved in bacteria
EMDOCAHE_01543 5.1e-176
EMDOCAHE_01544 2.4e-148
EMDOCAHE_01545 4.7e-13
EMDOCAHE_01546 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
EMDOCAHE_01547 8.5e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EMDOCAHE_01548 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
EMDOCAHE_01549 1.5e-71 yqhL P Rhodanese-like protein
EMDOCAHE_01550 1.2e-180 glk 2.7.1.2 G Glucokinase
EMDOCAHE_01551 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
EMDOCAHE_01552 2e-115 gluP 3.4.21.105 S Peptidase, S54 family
EMDOCAHE_01553 9.2e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EMDOCAHE_01554 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EMDOCAHE_01555 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
EMDOCAHE_01556 0.0 S membrane
EMDOCAHE_01557 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EMDOCAHE_01558 1.4e-116 udk 2.7.1.48 F Cytidine monophosphokinase
EMDOCAHE_01559 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EMDOCAHE_01560 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EMDOCAHE_01561 7.8e-60 yodB K Transcriptional regulator, HxlR family
EMDOCAHE_01562 7.6e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
EMDOCAHE_01563 1.2e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EMDOCAHE_01564 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EMDOCAHE_01565 1.7e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EMDOCAHE_01566 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EMDOCAHE_01567 8e-233 V MatE
EMDOCAHE_01568 9e-281 arlS 2.7.13.3 T Histidine kinase
EMDOCAHE_01569 5.6e-121 K response regulator
EMDOCAHE_01570 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EMDOCAHE_01571 1.3e-96 yceD S Uncharacterized ACR, COG1399
EMDOCAHE_01572 1.7e-215 ylbM S Belongs to the UPF0348 family
EMDOCAHE_01573 8.3e-142 yqeM Q Methyltransferase
EMDOCAHE_01574 4.6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EMDOCAHE_01575 7.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
EMDOCAHE_01576 5.4e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EMDOCAHE_01577 2.6e-49 yhbY J RNA-binding protein
EMDOCAHE_01578 2.6e-216 yqeH S Ribosome biogenesis GTPase YqeH
EMDOCAHE_01579 2.2e-96 yqeG S HAD phosphatase, family IIIA
EMDOCAHE_01580 1.6e-25 yoaK S Protein of unknown function (DUF1275)
EMDOCAHE_01581 1.9e-19 yoaK S Protein of unknown function (DUF1275)
EMDOCAHE_01582 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EMDOCAHE_01583 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EMDOCAHE_01584 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EMDOCAHE_01585 7.4e-172 dnaI L Primosomal protein DnaI
EMDOCAHE_01586 1e-251 dnaB L replication initiation and membrane attachment
EMDOCAHE_01587 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EMDOCAHE_01588 3.5e-106 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EMDOCAHE_01589 8e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EMDOCAHE_01590 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EMDOCAHE_01591 2.9e-139 aroD S Serine hydrolase (FSH1)
EMDOCAHE_01592 5.3e-114 ybhL S Belongs to the BI1 family
EMDOCAHE_01593 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EMDOCAHE_01594 2e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EMDOCAHE_01595 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EMDOCAHE_01596 3.3e-58 ytzB S Small secreted protein
EMDOCAHE_01597 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EMDOCAHE_01598 1.7e-210 ecsB U ABC transporter
EMDOCAHE_01599 2.3e-133 ecsA V ABC transporter, ATP-binding protein
EMDOCAHE_01600 1.4e-77 hit FG histidine triad
EMDOCAHE_01602 3.1e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EMDOCAHE_01603 5.7e-180 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
EMDOCAHE_01604 9.8e-56 yheA S Belongs to the UPF0342 family
EMDOCAHE_01605 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EMDOCAHE_01606 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
EMDOCAHE_01608 1.7e-36
EMDOCAHE_01610 2e-200 folP 2.5.1.15 H dihydropteroate synthase
EMDOCAHE_01611 2.2e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
EMDOCAHE_01612 4.9e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EMDOCAHE_01613 1.5e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
EMDOCAHE_01614 8.4e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
EMDOCAHE_01615 2.5e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EMDOCAHE_01616 2.4e-119 S CAAX protease self-immunity
EMDOCAHE_01617 9.9e-183 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
EMDOCAHE_01618 3.6e-111
EMDOCAHE_01619 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
EMDOCAHE_01620 1.8e-164 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EMDOCAHE_01621 1.2e-255 S Putative peptidoglycan binding domain
EMDOCAHE_01622 3.3e-86 uspA T Belongs to the universal stress protein A family
EMDOCAHE_01623 8.1e-276 pepV 3.5.1.18 E dipeptidase PepV
EMDOCAHE_01624 2.4e-156 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EMDOCAHE_01625 5e-63 3.2.1.23 S Domain of unknown function DUF302
EMDOCAHE_01626 3.6e-299 ytgP S Polysaccharide biosynthesis protein
EMDOCAHE_01627 2.6e-42
EMDOCAHE_01628 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EMDOCAHE_01629 6e-126 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
EMDOCAHE_01630 4.9e-224 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EMDOCAHE_01631 3.7e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EMDOCAHE_01632 3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EMDOCAHE_01633 8.5e-51
EMDOCAHE_01634 6.8e-98 tag 3.2.2.20 L glycosylase
EMDOCAHE_01635 5.2e-254 EGP Major facilitator Superfamily
EMDOCAHE_01636 4.8e-84 perR P Belongs to the Fur family
EMDOCAHE_01637 4.5e-247 cycA E Amino acid permease
EMDOCAHE_01638 4e-22
EMDOCAHE_01641 4.2e-239 L transposase, IS605 OrfB family
EMDOCAHE_01642 2.9e-81 tlpA2 L Transposase IS200 like
EMDOCAHE_01643 2e-94 K Transcriptional regulator, TetR family
EMDOCAHE_01644 3.7e-78 hsp O Belongs to the small heat shock protein (HSP20) family
EMDOCAHE_01645 1.6e-85 ykhA 3.1.2.20 I Thioesterase superfamily
EMDOCAHE_01646 2e-59 lytE M LysM domain protein
EMDOCAHE_01647 1.7e-201 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
EMDOCAHE_01648 6e-236 F Permease
EMDOCAHE_01649 1.3e-162 sufD O Uncharacterized protein family (UPF0051)
EMDOCAHE_01650 1.1e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EMDOCAHE_01651 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EMDOCAHE_01652 2e-110 XK27_05795 P ABC transporter permease
EMDOCAHE_01653 9e-142 ET Bacterial periplasmic substrate-binding proteins
EMDOCAHE_01654 1.3e-11 qacC P COG2076 Membrane transporters of cations and cationic drugs
EMDOCAHE_01657 1.2e-188 L PFAM Integrase, catalytic core
EMDOCAHE_01667 9.8e-77
EMDOCAHE_01670 2.8e-38 ykuJ S Protein of unknown function (DUF1797)
EMDOCAHE_01671 6.5e-182 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EMDOCAHE_01672 7.7e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
EMDOCAHE_01673 1.3e-229 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EMDOCAHE_01674 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EMDOCAHE_01675 4.7e-39 ptsH G phosphocarrier protein HPR
EMDOCAHE_01677 0.0 clpE O Belongs to the ClpA ClpB family
EMDOCAHE_01678 1.7e-128 3.6.1.13, 3.6.1.55 F NUDIX domain
EMDOCAHE_01679 6.4e-110 pncA Q Isochorismatase family
EMDOCAHE_01680 2e-266 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EMDOCAHE_01681 1.7e-97 S Pfam:DUF3816
EMDOCAHE_01682 1e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
EMDOCAHE_01683 8.4e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EMDOCAHE_01684 1.9e-161 EG EamA-like transporter family
EMDOCAHE_01685 1.2e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
EMDOCAHE_01686 4.8e-190 L Helix-turn-helix domain
EMDOCAHE_01687 2.1e-238 L transposase, IS605 OrfB family
EMDOCAHE_01688 1.4e-80 tlpA2 L Transposase IS200 like
EMDOCAHE_01689 5.5e-15
EMDOCAHE_01690 4.7e-157 V ABC transporter, ATP-binding protein
EMDOCAHE_01691 7.8e-64 gntR1 K Transcriptional regulator, GntR family
EMDOCAHE_01692 1.5e-172 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EMDOCAHE_01693 1.9e-88 S Bacterial membrane protein, YfhO
EMDOCAHE_01694 3.1e-103 glfT1 1.1.1.133 S Glycosyltransferase like family 2
EMDOCAHE_01695 1.3e-95 M transferase activity, transferring glycosyl groups
EMDOCAHE_01696 7.7e-307 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EMDOCAHE_01697 1.1e-133 L PFAM transposase, IS4 family protein
EMDOCAHE_01698 2e-164 ykoT GT2 M Glycosyl transferase family 2
EMDOCAHE_01699 1.8e-140 yueF S AI-2E family transporter
EMDOCAHE_01700 3.8e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
EMDOCAHE_01701 8.1e-09
EMDOCAHE_01702 3e-64 M repeat protein
EMDOCAHE_01703 4.2e-98 L Belongs to the 'phage' integrase family
EMDOCAHE_01704 4.9e-38 L Transposase and inactivated derivatives
EMDOCAHE_01705 1.7e-40 L COG2801 Transposase and inactivated derivatives
EMDOCAHE_01706 1.2e-169 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_01707 1.6e-38
EMDOCAHE_01708 1.5e-14 tra L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_01709 8.5e-229 tnp L MULE transposase domain
EMDOCAHE_01710 9.6e-76 S Psort location CytoplasmicMembrane, score
EMDOCAHE_01711 1.4e-64 acmD M repeat protein
EMDOCAHE_01712 3.3e-72 S enterobacterial common antigen metabolic process
EMDOCAHE_01713 9.3e-203 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
EMDOCAHE_01714 2.5e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
EMDOCAHE_01715 4.5e-45 M biosynthesis protein
EMDOCAHE_01716 1.2e-94 cps3F
EMDOCAHE_01717 4.6e-148 cps1D M Domain of unknown function (DUF4422)
EMDOCAHE_01718 1.1e-118 rfbP M Bacterial sugar transferase
EMDOCAHE_01719 4.2e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
EMDOCAHE_01720 1.3e-07
EMDOCAHE_01721 3.8e-31 S Protein of unknown function (DUF2922)
EMDOCAHE_01722 2.7e-139 yihY S Belongs to the UPF0761 family
EMDOCAHE_01723 0.0 XK27_08315 M Sulfatase
EMDOCAHE_01724 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
EMDOCAHE_01725 8.5e-78 fld C Flavodoxin
EMDOCAHE_01726 8.6e-75 gtcA S Teichoic acid glycosylation protein
EMDOCAHE_01728 4.4e-231 yfmL 3.6.4.13 L DEAD DEAH box helicase
EMDOCAHE_01729 1.3e-190 mocA S Oxidoreductase
EMDOCAHE_01730 1.4e-62 S Domain of unknown function (DUF4828)
EMDOCAHE_01731 1.4e-104 yvdD 3.2.2.10 S Belongs to the LOG family
EMDOCAHE_01732 3.3e-161 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EMDOCAHE_01733 1.5e-288 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
EMDOCAHE_01734 4.7e-140 S NADPH-dependent FMN reductase
EMDOCAHE_01735 2.3e-33 yneR S Belongs to the HesB IscA family
EMDOCAHE_01736 1.3e-304 ybiT S ABC transporter, ATP-binding protein
EMDOCAHE_01737 2.8e-143 L transposase, IS605 OrfB family
EMDOCAHE_01738 1.2e-188 L PFAM Integrase, catalytic core
EMDOCAHE_01739 2.3e-47 L transposase, IS605 OrfB family
EMDOCAHE_01740 2e-85 dps P Belongs to the Dps family
EMDOCAHE_01741 1.6e-105
EMDOCAHE_01742 1.3e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EMDOCAHE_01743 1.4e-101 K helix_turn_helix multiple antibiotic resistance protein
EMDOCAHE_01744 3.4e-49 fsr EGP Major Facilitator Superfamily
EMDOCAHE_01745 5.1e-81 fsr EGP Major Facilitator Superfamily
EMDOCAHE_01746 2.7e-99 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EMDOCAHE_01747 1.7e-102 S CAAX protease self-immunity
EMDOCAHE_01749 1.1e-119 Q Methyltransferase domain
EMDOCAHE_01750 8.6e-91 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
EMDOCAHE_01751 2.8e-51 K 2 iron, 2 sulfur cluster binding
EMDOCAHE_01752 0.0 mco Q Multicopper oxidase
EMDOCAHE_01753 7.1e-89 S Aminoacyl-tRNA editing domain
EMDOCAHE_01754 3.1e-75 ddaH 3.5.3.18 E Amidinotransferase
EMDOCAHE_01756 3.5e-194 nhaC C Na H antiporter NhaC
EMDOCAHE_01757 1.8e-185 S Phosphotransferase system, EIIC
EMDOCAHE_01758 5.1e-22 D mRNA cleavage
EMDOCAHE_01759 3.2e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
EMDOCAHE_01760 6.6e-47 L Transposase
EMDOCAHE_01761 3.9e-167 L Integrase core domain
EMDOCAHE_01763 6e-157 L hmm pf00665
EMDOCAHE_01764 4.3e-28 L hmm pf00665
EMDOCAHE_01765 6.7e-110 L Integrase core domain
EMDOCAHE_01766 1.9e-46 L Transposase
EMDOCAHE_01767 4.7e-77 S Protease prsW family
EMDOCAHE_01769 6.2e-154 L Integrase core domain
EMDOCAHE_01770 8.3e-38 L Transposase and inactivated derivatives
EMDOCAHE_01772 1.1e-225 L Transposase
EMDOCAHE_01773 4.1e-113 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
EMDOCAHE_01774 5.4e-46 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
EMDOCAHE_01775 5.6e-33 copZ P Heavy-metal-associated domain
EMDOCAHE_01776 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
EMDOCAHE_01777 9.8e-82
EMDOCAHE_01778 2.2e-81 tlpA2 L Transposase IS200 like
EMDOCAHE_01779 4.2e-236 L transposase, IS605 OrfB family
EMDOCAHE_01780 2.8e-182 tnp L MULE transposase domain
EMDOCAHE_01781 8e-224 L Transposase
EMDOCAHE_01782 9.6e-38 tnp L MULE transposase domain
EMDOCAHE_01783 5.5e-214 tra L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_01784 1.4e-49 K TRANSCRIPTIONal
EMDOCAHE_01786 5.4e-237 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
EMDOCAHE_01787 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
EMDOCAHE_01788 3.3e-79 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_01789 3.3e-39 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
EMDOCAHE_01790 1.9e-143 xerC L Belongs to the 'phage' integrase family
EMDOCAHE_01791 4.6e-59 3.1.21.3 V Type I restriction modification DNA specificity domain
EMDOCAHE_01792 2.8e-285 2.1.1.72 V type I restriction-modification system
EMDOCAHE_01793 1.3e-28 K Cro/C1-type HTH DNA-binding domain
EMDOCAHE_01794 2.9e-101
EMDOCAHE_01795 7.2e-56 K DNA-templated transcription, initiation
EMDOCAHE_01796 5.5e-24
EMDOCAHE_01797 8e-28
EMDOCAHE_01798 1.5e-203 L Protein of unknown function (DUF2800)
EMDOCAHE_01799 4.4e-92 S Protein of unknown function (DUF2815)
EMDOCAHE_01800 1.2e-188 L PFAM Integrase, catalytic core
EMDOCAHE_01801 0.0 polA_2 2.7.7.7 L DNA polymerase
EMDOCAHE_01802 5.9e-67 S Psort location Cytoplasmic, score
EMDOCAHE_01803 0.0 S Phage plasmid primase, P4
EMDOCAHE_01804 2.9e-47 S VRR_NUC
EMDOCAHE_01805 8.2e-249 L SNF2 family N-terminal domain
EMDOCAHE_01806 3.4e-85
EMDOCAHE_01807 4.8e-72
EMDOCAHE_01808 5.6e-145 2.1.1.72 KL DNA methylase
EMDOCAHE_01809 2.9e-170 L Integrase core domain
EMDOCAHE_01810 9.5e-46 L Transposase
EMDOCAHE_01811 5.1e-38 2.1.1.72 KL DNA methylase
EMDOCAHE_01812 3.4e-101 S Psort location Cytoplasmic, score
EMDOCAHE_01813 2.9e-28 S Domain of unknown function (DUF5049)
EMDOCAHE_01814 4e-300 S overlaps another CDS with the same product name
EMDOCAHE_01815 1.4e-242 S Phage portal protein
EMDOCAHE_01816 1.4e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
EMDOCAHE_01817 2.2e-218 S Phage capsid family
EMDOCAHE_01818 4.3e-43 S Phage gp6-like head-tail connector protein
EMDOCAHE_01819 8.4e-66 S Phage head-tail joining protein
EMDOCAHE_01820 4.3e-68 S Bacteriophage holin family
EMDOCAHE_01821 4.8e-32
EMDOCAHE_01822 1.1e-274 L Recombinase zinc beta ribbon domain
EMDOCAHE_01823 1.7e-285 L Recombinase
EMDOCAHE_01824 6.3e-16 2.1.1.303 K DNA-binding transcription factor activity
EMDOCAHE_01825 1.5e-197 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EMDOCAHE_01826 1.9e-225 L Transposase
EMDOCAHE_01827 8.6e-133 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EMDOCAHE_01828 3.2e-264 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EMDOCAHE_01829 1.9e-186 yegS 2.7.1.107 G Lipid kinase
EMDOCAHE_01830 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EMDOCAHE_01831 6.7e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EMDOCAHE_01832 1e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EMDOCAHE_01833 3.2e-166 camS S sex pheromone
EMDOCAHE_01834 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EMDOCAHE_01835 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EMDOCAHE_01836 1.4e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EMDOCAHE_01837 3.2e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EMDOCAHE_01838 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
EMDOCAHE_01839 1.2e-138 IQ reductase
EMDOCAHE_01840 4.1e-190 S interspecies interaction between organisms
EMDOCAHE_01841 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
EMDOCAHE_01842 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EMDOCAHE_01843 2.2e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EMDOCAHE_01844 1.1e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EMDOCAHE_01845 2e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EMDOCAHE_01846 2e-149 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EMDOCAHE_01847 2.8e-61 rplQ J Ribosomal protein L17
EMDOCAHE_01848 2e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EMDOCAHE_01849 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EMDOCAHE_01850 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EMDOCAHE_01851 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EMDOCAHE_01852 1e-31 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EMDOCAHE_01853 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EMDOCAHE_01854 3.8e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EMDOCAHE_01855 2.1e-65 rplO J Binds to the 23S rRNA
EMDOCAHE_01856 2.5e-23 rpmD J Ribosomal protein L30
EMDOCAHE_01857 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EMDOCAHE_01858 3.9e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EMDOCAHE_01859 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EMDOCAHE_01860 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EMDOCAHE_01861 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EMDOCAHE_01862 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EMDOCAHE_01863 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EMDOCAHE_01864 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EMDOCAHE_01865 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EMDOCAHE_01866 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
EMDOCAHE_01867 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EMDOCAHE_01868 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EMDOCAHE_01869 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EMDOCAHE_01870 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EMDOCAHE_01871 3.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EMDOCAHE_01872 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EMDOCAHE_01873 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
EMDOCAHE_01874 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EMDOCAHE_01875 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
EMDOCAHE_01876 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EMDOCAHE_01877 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EMDOCAHE_01878 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EMDOCAHE_01879 6.2e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
EMDOCAHE_01880 2.2e-213 ykiI
EMDOCAHE_01881 5.6e-135 puuD S peptidase C26
EMDOCAHE_01882 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EMDOCAHE_01883 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EMDOCAHE_01884 5.8e-106 K Bacterial regulatory proteins, tetR family
EMDOCAHE_01885 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EMDOCAHE_01886 4.8e-79 ctsR K Belongs to the CtsR family
EMDOCAHE_01887 2.8e-193 adhP 1.1.1.1 C alcohol dehydrogenase
EMDOCAHE_01888 1.3e-131 XK27_07210 6.1.1.6 S B3 4 domain
EMDOCAHE_01889 7.9e-120 J 2'-5' RNA ligase superfamily
EMDOCAHE_01890 1.1e-29 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
EMDOCAHE_01891 1.6e-185 L transposase, IS605 OrfB family
EMDOCAHE_01892 1.3e-44 L Transposase IS200 like
EMDOCAHE_01893 2.9e-137 L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_01894 2.8e-46 rmeB K transcriptional regulator, MerR family
EMDOCAHE_01895 7.9e-72 thiW S Thiamine-precursor transporter protein (ThiW)
EMDOCAHE_01896 9.1e-40 S ABC-type cobalt transport system, permease component
EMDOCAHE_01897 1.2e-16 S ABC-type cobalt transport system, permease component
EMDOCAHE_01898 9.4e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EMDOCAHE_01899 1e-31 IQ reductase
EMDOCAHE_01900 2.6e-17 IQ reductase
EMDOCAHE_01901 2e-11 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EMDOCAHE_01907 7.9e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
EMDOCAHE_01908 3.9e-268 lysP E amino acid
EMDOCAHE_01910 1.8e-155 I alpha/beta hydrolase fold
EMDOCAHE_01911 9.1e-116 lssY 3.6.1.27 I phosphatase
EMDOCAHE_01912 2.8e-82 S Threonine/Serine exporter, ThrE
EMDOCAHE_01913 3.2e-125 thrE S Putative threonine/serine exporter
EMDOCAHE_01914 6.2e-246 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EMDOCAHE_01915 1.2e-188 L PFAM Integrase, catalytic core
EMDOCAHE_01916 1.3e-30 cspA K Cold shock protein
EMDOCAHE_01917 1.2e-123 sirR K iron dependent repressor
EMDOCAHE_01918 1.6e-163 czcD P cation diffusion facilitator family transporter
EMDOCAHE_01919 2e-113 S membrane
EMDOCAHE_01920 2.2e-109 S VIT family
EMDOCAHE_01921 4.5e-85 usp1 T Belongs to the universal stress protein A family
EMDOCAHE_01922 2.4e-32 elaA S GNAT family
EMDOCAHE_01923 8.2e-216 S CAAX protease self-immunity
EMDOCAHE_01924 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EMDOCAHE_01925 2e-58
EMDOCAHE_01926 1.9e-74 merR K MerR HTH family regulatory protein
EMDOCAHE_01927 1.4e-265 lmrB EGP Major facilitator Superfamily
EMDOCAHE_01928 2e-113 S Domain of unknown function (DUF4811)
EMDOCAHE_01929 5.5e-149 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
EMDOCAHE_01930 1.1e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EMDOCAHE_01932 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EMDOCAHE_01933 2.7e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
EMDOCAHE_01934 9.1e-189 I Alpha beta
EMDOCAHE_01935 2.1e-120 ung2 3.2.2.27 L Uracil-DNA glycosylase
EMDOCAHE_01936 1.9e-253 yjjP S Putative threonine/serine exporter
EMDOCAHE_01937 1.7e-162 mleR K LysR family transcriptional regulator
EMDOCAHE_01938 2e-146 ydjP I Alpha/beta hydrolase family
EMDOCAHE_01939 2.3e-257 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
EMDOCAHE_01940 1.7e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
EMDOCAHE_01941 4.2e-164 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
EMDOCAHE_01942 5.7e-46 citD C Covalent carrier of the coenzyme of citrate lyase
EMDOCAHE_01943 8.1e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EMDOCAHE_01944 2.9e-210 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
EMDOCAHE_01945 1.2e-174 citR K sugar-binding domain protein
EMDOCAHE_01946 6.2e-231 P Sodium:sulfate symporter transmembrane region
EMDOCAHE_01947 1e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EMDOCAHE_01948 2.4e-219 frdC 1.3.5.4 C FAD binding domain
EMDOCAHE_01949 6.1e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EMDOCAHE_01950 1.9e-91 XK27_09620 S NADPH-dependent FMN reductase
EMDOCAHE_01951 1.7e-182 XK27_09615 S reductase
EMDOCAHE_01952 7.2e-231 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
EMDOCAHE_01953 1.1e-79 mleR K LysR family
EMDOCAHE_01954 8.2e-26 nlhH_1 I Carboxylesterase family
EMDOCAHE_01955 2.6e-133 L PFAM transposase, IS4 family protein
EMDOCAHE_01956 9e-28 nlhH_1 I acetylesterase activity
EMDOCAHE_01957 3.6e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EMDOCAHE_01958 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
EMDOCAHE_01959 1.8e-195 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
EMDOCAHE_01960 4.5e-301 scrB 3.2.1.26 GH32 G invertase
EMDOCAHE_01961 1.9e-261 S Uncharacterized protein conserved in bacteria (DUF2252)
EMDOCAHE_01962 3.2e-164 K LysR substrate binding domain
EMDOCAHE_01963 2.6e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
EMDOCAHE_01964 5.5e-112
EMDOCAHE_01966 9e-265 yjeM E Amino Acid
EMDOCAHE_01967 2e-169 ponA V Beta-lactamase enzyme family
EMDOCAHE_01968 1.7e-224 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EMDOCAHE_01969 1.3e-96
EMDOCAHE_01970 5.9e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
EMDOCAHE_01971 6.8e-107 lssY 3.6.1.27 I Acid phosphatase homologues
EMDOCAHE_01972 1.6e-54 S MazG-like family
EMDOCAHE_01973 0.0 L Helicase C-terminal domain protein
EMDOCAHE_01974 3.2e-71 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
EMDOCAHE_01975 7.7e-97 K transcriptional regulator
EMDOCAHE_01976 2.3e-137 lmrB EGP Major facilitator Superfamily
EMDOCAHE_01978 4.4e-12 yfjR K Psort location Cytoplasmic, score
EMDOCAHE_01979 3.5e-38 S Cytochrome B5
EMDOCAHE_01980 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EMDOCAHE_01981 4.9e-215 2.1.1.14 E methionine synthase, vitamin-B12 independent
EMDOCAHE_01982 6e-238 L transposase, IS605 OrfB family
EMDOCAHE_01983 1.1e-80 tlpA2 L Transposase IS200 like
EMDOCAHE_01984 5.7e-22 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
EMDOCAHE_01985 8.7e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
EMDOCAHE_01986 6.4e-105 3.2.1.17 NU mannosyl-glycoprotein
EMDOCAHE_01987 1.1e-95 wecD K Acetyltransferase (GNAT) family
EMDOCAHE_01988 1.9e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
EMDOCAHE_01989 2.9e-81 S Psort location Cytoplasmic, score
EMDOCAHE_01990 7.3e-71 K helix_turn_helix, mercury resistance
EMDOCAHE_01991 7.9e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
EMDOCAHE_01992 5e-190 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
EMDOCAHE_01993 4.8e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EMDOCAHE_01994 2.2e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
EMDOCAHE_01995 7.8e-124 ycsF S LamB/YcsF family
EMDOCAHE_01996 2.7e-211 ycsG P Natural resistance-associated macrophage protein
EMDOCAHE_01997 1.6e-208 EGP Major facilitator Superfamily
EMDOCAHE_01998 1.7e-254 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
EMDOCAHE_01999 1.1e-52 trxA O Belongs to the thioredoxin family
EMDOCAHE_02000 1e-120 mleP3 S Membrane transport protein
EMDOCAHE_02001 7.1e-239 L transposase, IS605 OrfB family
EMDOCAHE_02002 2.9e-81 tlpA2 L Transposase IS200 like
EMDOCAHE_02004 2e-242 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EMDOCAHE_02005 5.7e-240 yfnA E amino acid
EMDOCAHE_02006 3.5e-58 S NADPH-dependent FMN reductase
EMDOCAHE_02008 1.5e-155 L Thioesterase-like superfamily
EMDOCAHE_02009 1.1e-50 lacA S transferase hexapeptide repeat
EMDOCAHE_02010 2.1e-260 argH 4.3.2.1 E argininosuccinate lyase
EMDOCAHE_02011 1.8e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EMDOCAHE_02012 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EMDOCAHE_02013 2.2e-102 K Transcriptional regulator
EMDOCAHE_02014 1.8e-18 XK27_06785 V ABC transporter
EMDOCAHE_02015 1.6e-140 M Membrane
EMDOCAHE_02016 3e-57 S FMN_bind
EMDOCAHE_02017 0.0 yhcA V ABC transporter, ATP-binding protein
EMDOCAHE_02018 5.5e-124 bm3R1 K Bacterial regulatory proteins, tetR family
EMDOCAHE_02019 2.6e-231 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EMDOCAHE_02020 2e-49 ybjQ S Belongs to the UPF0145 family
EMDOCAHE_02021 2.5e-73 rocF 3.5.3.1, 3.5.3.11 E Arginase family
EMDOCAHE_02023 5.1e-173 1.3.1.9 S Nitronate monooxygenase
EMDOCAHE_02024 4.7e-54 K Helix-turn-helix domain
EMDOCAHE_02025 1.2e-105 S Domain of unknown function (DUF4767)
EMDOCAHE_02026 5.8e-113
EMDOCAHE_02028 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
EMDOCAHE_02029 0.0 norZ 1.7.2.5 P Cytochrome C and Quinol oxidase polypeptide I
EMDOCAHE_02030 5.7e-270 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EMDOCAHE_02031 9.2e-115 2.7.6.5 T Region found in RelA / SpoT proteins
EMDOCAHE_02032 8e-80 K response regulator
EMDOCAHE_02033 2.4e-130 sptS 2.7.13.3 T Histidine kinase
EMDOCAHE_02034 5.3e-175 coaA 2.7.1.33 F Pantothenic acid kinase
EMDOCAHE_02035 2.3e-104 2.3.1.128 K acetyltransferase
EMDOCAHE_02036 3.4e-135 IQ Dehydrogenase reductase
EMDOCAHE_02037 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EMDOCAHE_02038 3.6e-160 EG EamA-like transporter family
EMDOCAHE_02039 0.0 helD 3.6.4.12 L DNA helicase
EMDOCAHE_02040 4.3e-118 dedA S SNARE associated Golgi protein
EMDOCAHE_02041 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
EMDOCAHE_02042 5e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EMDOCAHE_02043 4.7e-210 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EMDOCAHE_02044 3e-133 pnuC H nicotinamide mononucleotide transporter
EMDOCAHE_02045 1.7e-298 ybeC E amino acid
EMDOCAHE_02046 1e-79 K FR47-like protein
EMDOCAHE_02047 5.3e-207 V domain protein
EMDOCAHE_02048 1.9e-92 K Transcriptional regulator (TetR family)
EMDOCAHE_02049 8.1e-188 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EMDOCAHE_02050 6.3e-168
EMDOCAHE_02052 4e-83 zur P Belongs to the Fur family
EMDOCAHE_02053 1.7e-105 gmk2 2.7.4.8 F Guanylate kinase
EMDOCAHE_02054 1.3e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
EMDOCAHE_02055 1.1e-205 yfnA E Amino Acid
EMDOCAHE_02056 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EMDOCAHE_02057 1.6e-238 L transposase, IS605 OrfB family
EMDOCAHE_02058 7.6e-82 tlpA2 L Transposase IS200 like
EMDOCAHE_02059 3.1e-178 3.4.11.5 E Releases the N-terminal proline from various substrates
EMDOCAHE_02060 2.3e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
EMDOCAHE_02061 5e-275 S Uncharacterized protein conserved in bacteria (DUF2325)
EMDOCAHE_02062 1.2e-182 1.17.4.1 F Ribonucleotide reductase, small chain
EMDOCAHE_02063 9.7e-169 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
EMDOCAHE_02064 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EMDOCAHE_02065 1.4e-83 nrdI F NrdI Flavodoxin like
EMDOCAHE_02066 5.1e-110 M ErfK YbiS YcfS YnhG
EMDOCAHE_02068 8.9e-206 nrnB S DHHA1 domain
EMDOCAHE_02069 3.4e-291 S ABC transporter, ATP-binding protein
EMDOCAHE_02070 5.9e-180 ABC-SBP S ABC transporter
EMDOCAHE_02071 1e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
EMDOCAHE_02072 2.1e-132 XK27_08845 S ABC transporter, ATP-binding protein
EMDOCAHE_02074 9.7e-225 amtB P ammonium transporter
EMDOCAHE_02075 4.3e-234 mepA V MATE efflux family protein
EMDOCAHE_02076 2.9e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
EMDOCAHE_02077 1.3e-257 pgi 5.3.1.9 G Belongs to the GPI family
EMDOCAHE_02078 8.8e-184 fruR3 K Transcriptional regulator, LacI family
EMDOCAHE_02079 5e-162 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
EMDOCAHE_02080 2.6e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EMDOCAHE_02081 1e-56 trxA1 O Belongs to the thioredoxin family
EMDOCAHE_02082 5.2e-142 terC P membrane
EMDOCAHE_02083 9.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EMDOCAHE_02084 1.4e-170 corA P CorA-like Mg2+ transporter protein
EMDOCAHE_02085 8.4e-230 pbuX F xanthine permease
EMDOCAHE_02086 8.3e-51 L Helix-turn-helix domain
EMDOCAHE_02087 6.2e-85 L hmm pf00665
EMDOCAHE_02088 1.9e-150 qorB 1.6.5.2 GM NmrA-like family
EMDOCAHE_02089 2.5e-126 pgm3 G phosphoglycerate mutase family
EMDOCAHE_02090 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EMDOCAHE_02091 2e-85
EMDOCAHE_02092 4.4e-107 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
EMDOCAHE_02093 2.6e-100 dps P Belongs to the Dps family
EMDOCAHE_02094 2.8e-32 copZ P Heavy-metal-associated domain
EMDOCAHE_02095 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
EMDOCAHE_02096 4.4e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
EMDOCAHE_02097 3.1e-178 iunH2 3.2.2.1 F nucleoside hydrolase
EMDOCAHE_02098 1.6e-100 S ABC-type cobalt transport system, permease component
EMDOCAHE_02099 1.6e-255 cbiO1 S ABC transporter, ATP-binding protein
EMDOCAHE_02100 7.5e-115 P Cobalt transport protein
EMDOCAHE_02101 1.2e-16 yvlA
EMDOCAHE_02102 0.0 yjcE P Sodium proton antiporter
EMDOCAHE_02103 4e-192 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
EMDOCAHE_02104 1.6e-73 O OsmC-like protein
EMDOCAHE_02105 2.8e-187 D Alpha beta
EMDOCAHE_02106 8.4e-75 K Transcriptional regulator
EMDOCAHE_02107 4.5e-160
EMDOCAHE_02108 6.6e-20
EMDOCAHE_02109 2.1e-59
EMDOCAHE_02110 3.1e-75 uspA T universal stress protein
EMDOCAHE_02112 1.3e-129 qmcA O prohibitin homologues
EMDOCAHE_02113 1.6e-244 glpT G Major Facilitator Superfamily
EMDOCAHE_02114 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EMDOCAHE_02115 6.7e-136 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
EMDOCAHE_02116 1.7e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EMDOCAHE_02117 2.7e-116 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EMDOCAHE_02118 1.8e-58 L Helix-turn-helix domain
EMDOCAHE_02119 1.3e-156 L hmm pf00665
EMDOCAHE_02120 6.2e-185 hoxN U High-affinity nickel-transport protein
EMDOCAHE_02121 1.7e-148 larE S NAD synthase
EMDOCAHE_02122 4.5e-129 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
EMDOCAHE_02123 2.4e-216 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EMDOCAHE_02124 8.5e-229 tnp L MULE transposase domain
EMDOCAHE_02125 1.5e-110 cpmA S AIR carboxylase
EMDOCAHE_02126 3.6e-241 larA 5.1.2.1 S Domain of unknown function (DUF2088)
EMDOCAHE_02127 7e-124 K Crp-like helix-turn-helix domain
EMDOCAHE_02128 4.8e-190 L Helix-turn-helix domain
EMDOCAHE_02129 8.3e-100 L hmm pf00665
EMDOCAHE_02130 1.1e-225 L Transposase
EMDOCAHE_02131 8.6e-38 L hmm pf00665
EMDOCAHE_02132 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EMDOCAHE_02133 2.7e-244 fucP G Major Facilitator Superfamily
EMDOCAHE_02134 2.1e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EMDOCAHE_02135 2.5e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EMDOCAHE_02136 1.2e-169 deoR K sugar-binding domain protein
EMDOCAHE_02137 9.8e-115 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EMDOCAHE_02138 1.1e-200 S Domain of unknown function (DUF4432)
EMDOCAHE_02139 3.2e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EMDOCAHE_02140 9.8e-261 G PTS system Galactitol-specific IIC component
EMDOCAHE_02141 1.7e-187 K helix_turn _helix lactose operon repressor
EMDOCAHE_02142 1.4e-281 yjeM E Amino Acid
EMDOCAHE_02143 2.6e-133 L PFAM transposase, IS4 family protein
EMDOCAHE_02145 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
EMDOCAHE_02146 1.1e-149 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
EMDOCAHE_02147 6.4e-131 gntR K UbiC transcription regulator-associated domain protein
EMDOCAHE_02148 7.1e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EMDOCAHE_02149 2.7e-129
EMDOCAHE_02150 2.3e-265 pipD E Dipeptidase
EMDOCAHE_02151 2.6e-157 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
EMDOCAHE_02152 3.4e-86 M1-874 K Domain of unknown function (DUF1836)
EMDOCAHE_02153 3e-90 GM epimerase
EMDOCAHE_02154 3.6e-252 yhdP S Transporter associated domain
EMDOCAHE_02155 2.4e-83 nrdI F Belongs to the NrdI family
EMDOCAHE_02156 6.5e-75 S 3-demethylubiquinone-9 3-methyltransferase
EMDOCAHE_02157 1.1e-206 yeaN P Transporter, major facilitator family protein
EMDOCAHE_02158 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EMDOCAHE_02159 9.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EMDOCAHE_02160 1.4e-81 uspA T universal stress protein
EMDOCAHE_02161 1.9e-77 K AsnC family
EMDOCAHE_02162 3.3e-138 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EMDOCAHE_02163 2.1e-177 K helix_turn _helix lactose operon repressor
EMDOCAHE_02164 0.0 pepF E oligoendopeptidase F
EMDOCAHE_02165 5.4e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EMDOCAHE_02166 7e-124 S Membrane
EMDOCAHE_02167 1.3e-28 L Transposase
EMDOCAHE_02168 2.1e-145 L 4.5 Transposon and IS
EMDOCAHE_02169 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding
EMDOCAHE_02170 2.2e-22 L hmm pf00665
EMDOCAHE_02171 2.4e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EMDOCAHE_02173 8e-219 tnp L MULE transposase domain
EMDOCAHE_02174 8e-108 tnp L MULE transposase domain
EMDOCAHE_02175 1e-38 mdt(A) EGP Major facilitator Superfamily
EMDOCAHE_02176 1.4e-56 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
EMDOCAHE_02177 5.9e-188 L Helix-turn-helix domain
EMDOCAHE_02178 1.1e-245 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EMDOCAHE_02179 4e-69 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EMDOCAHE_02180 7.1e-186 L PFAM Integrase catalytic region
EMDOCAHE_02181 3.1e-19 T Antidote-toxin recognition MazE, bacterial antitoxin
EMDOCAHE_02182 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
EMDOCAHE_02183 3.3e-217 tnp L MULE transposase domain
EMDOCAHE_02185 0.0 copB 3.6.3.4 P P-type ATPase
EMDOCAHE_02186 1.9e-74 K Copper transport repressor CopY TcrY
EMDOCAHE_02187 2.7e-76 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
EMDOCAHE_02188 5.3e-116 devA 3.6.3.25 V ABC transporter, ATP-binding protein
EMDOCAHE_02189 1.7e-161 hrtB V ABC transporter permease
EMDOCAHE_02190 1.4e-72 crtB 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
EMDOCAHE_02191 7.4e-26 L Helix-turn-helix domain
EMDOCAHE_02192 1.3e-156 L hmm pf00665
EMDOCAHE_02193 1.7e-276 lacS G Transporter
EMDOCAHE_02194 0.0 rafA 3.2.1.22 G alpha-galactosidase
EMDOCAHE_02195 2.9e-182 galR K Transcriptional regulator
EMDOCAHE_02196 5.8e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EMDOCAHE_02197 2.1e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EMDOCAHE_02198 7.7e-185 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
EMDOCAHE_02199 1.6e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
EMDOCAHE_02200 1e-95 yxkA S Phosphatidylethanolamine-binding protein
EMDOCAHE_02201 2e-35
EMDOCAHE_02202 8.7e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EMDOCAHE_02203 9e-119 tcyB U Binding-protein-dependent transport system inner membrane component
EMDOCAHE_02204 5.7e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
EMDOCAHE_02205 2e-52
EMDOCAHE_02206 2.6e-169 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMDOCAHE_02207 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EMDOCAHE_02208 6.9e-147 pnuC H nicotinamide mononucleotide transporter
EMDOCAHE_02209 4.1e-92 ymdB S Macro domain protein
EMDOCAHE_02210 0.0 pepO 3.4.24.71 O Peptidase family M13
EMDOCAHE_02211 2e-228 pbuG S permease
EMDOCAHE_02212 2.1e-45
EMDOCAHE_02213 9.9e-214 S Putative metallopeptidase domain
EMDOCAHE_02214 8e-205 3.1.3.1 S associated with various cellular activities
EMDOCAHE_02215 1.3e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
EMDOCAHE_02216 6.8e-65 yeaO S Protein of unknown function, DUF488
EMDOCAHE_02218 4.8e-125 yrkL S Flavodoxin-like fold
EMDOCAHE_02219 3.3e-55
EMDOCAHE_02220 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
EMDOCAHE_02221 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EMDOCAHE_02222 3.2e-102
EMDOCAHE_02223 9.5e-26
EMDOCAHE_02224 6.3e-171 scrR K Transcriptional regulator, LacI family
EMDOCAHE_02225 2.1e-171 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EMDOCAHE_02226 2.6e-46 czrA K Transcriptional regulator, ArsR family
EMDOCAHE_02227 5.4e-239 L transposase, IS605 OrfB family
EMDOCAHE_02228 1.5e-82 tlpA2 L Transposase IS200 like
EMDOCAHE_02229 1.8e-75 argR K Regulates arginine biosynthesis genes
EMDOCAHE_02230 3.9e-122 devA 3.6.3.25 V ABC transporter, ATP-binding protein
EMDOCAHE_02231 3.3e-157 hrtB V ABC transporter permease
EMDOCAHE_02232 1.2e-106 ygfC K Bacterial regulatory proteins, tetR family
EMDOCAHE_02233 2.3e-87 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
EMDOCAHE_02234 5.5e-172 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EMDOCAHE_02235 4.3e-138 L transposase, IS605 OrfB family
EMDOCAHE_02236 1.7e-73 tlpA2 L Transposase IS200 like
EMDOCAHE_02237 4.7e-224 L Transposase
EMDOCAHE_02238 4e-245 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EMDOCAHE_02239 1.4e-252 mntH P H( )-stimulated, divalent metal cation uptake system
EMDOCAHE_02240 1.5e-21
EMDOCAHE_02241 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EMDOCAHE_02242 9.6e-39 L nuclease
EMDOCAHE_02243 1.4e-161 F DNA/RNA non-specific endonuclease
EMDOCAHE_02244 4.5e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EMDOCAHE_02245 1.1e-289 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EMDOCAHE_02246 8.9e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EMDOCAHE_02247 0.0 asnB 6.3.5.4 E Asparagine synthase
EMDOCAHE_02248 6.6e-220 lysP E amino acid
EMDOCAHE_02249 7e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EMDOCAHE_02250 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EMDOCAHE_02251 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EMDOCAHE_02252 6.3e-154 jag S R3H domain protein
EMDOCAHE_02253 3.4e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EMDOCAHE_02254 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EMDOCAHE_02255 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)