ORF_ID e_value Gene_name EC_number CAZy COGs Description
OOONCIOL_00001 7.6e-222 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
OOONCIOL_00002 6.3e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OOONCIOL_00004 6.1e-236 norM V Multidrug efflux pump
OOONCIOL_00005 2.2e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OOONCIOL_00006 5.6e-126 yojG S deacetylase
OOONCIOL_00007 3.7e-60 yojF S Protein of unknown function (DUF1806)
OOONCIOL_00008 4.9e-23
OOONCIOL_00009 2.5e-161 rarD S -transporter
OOONCIOL_00010 7.3e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
OOONCIOL_00012 5.9e-67 yodA S tautomerase
OOONCIOL_00013 2.3e-68 yoaQ S Evidence 4 Homologs of previously reported genes of
OOONCIOL_00014 3e-56 yodB K transcriptional
OOONCIOL_00015 4.5e-106 yodC C nitroreductase
OOONCIOL_00016 5.7e-109 mhqD S Carboxylesterase
OOONCIOL_00017 1e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
OOONCIOL_00018 1.4e-19 S Protein of unknown function (DUF3311)
OOONCIOL_00019 4.3e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OOONCIOL_00020 3e-276 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
OOONCIOL_00021 5.6e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OOONCIOL_00022 2.6e-132 yydK K Transcriptional regulator
OOONCIOL_00023 1.5e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
OOONCIOL_00024 7e-127 yodH Q Methyltransferase
OOONCIOL_00025 1.9e-21 yodI
OOONCIOL_00026 8.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
OOONCIOL_00027 5.9e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
OOONCIOL_00029 3.3e-55 yodL S YodL-like
OOONCIOL_00030 2e-101 yodM 3.6.1.27 I Acid phosphatase homologues
OOONCIOL_00031 6.2e-24 yozD S YozD-like protein
OOONCIOL_00033 1.7e-125 yodN
OOONCIOL_00034 9.1e-36 yozE S Belongs to the UPF0346 family
OOONCIOL_00035 9.2e-46 yokU S YokU-like protein, putative antitoxin
OOONCIOL_00036 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
OOONCIOL_00037 9.8e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
OOONCIOL_00038 9e-253 yodQ 3.5.1.16 E Acetylornithine deacetylase
OOONCIOL_00039 8e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OOONCIOL_00040 8.4e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OOONCIOL_00041 1.9e-245 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OOONCIOL_00042 1.4e-64 yosT L Bacterial transcription activator, effector binding domain
OOONCIOL_00044 9.2e-144 yiiD K acetyltransferase
OOONCIOL_00045 4.5e-241 cgeD M maturation of the outermost layer of the spore
OOONCIOL_00046 1.2e-40 cgeC
OOONCIOL_00047 1.6e-52 cgeA
OOONCIOL_00048 1.4e-178 cgeB S Spore maturation protein
OOONCIOL_00049 2.6e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
OOONCIOL_00050 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
OOONCIOL_00056 1.7e-77
OOONCIOL_00057 2.6e-08
OOONCIOL_00060 3.1e-75 yoqH M LysM domain
OOONCIOL_00061 1.9e-206 S aspartate phosphatase
OOONCIOL_00063 3.5e-88 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OOONCIOL_00064 9.1e-275 baeB 3.1.2.6, 3.4.21.102 P Rhodanese Homology Domain
OOONCIOL_00065 5.4e-228 fccB 1.8.5.4 S Pyridine nucleotide-disulphide oxidoreductase
OOONCIOL_00066 2.9e-95 nreC T helix_turn_helix, Lux Regulon
OOONCIOL_00067 1.5e-197 2.7.13.3 T Histidine kinase
OOONCIOL_00068 1.4e-51 S SMI1-KNR4 cell-wall
OOONCIOL_00069 2.1e-53 L nuclease activity
OOONCIOL_00070 5.2e-143 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OOONCIOL_00071 3.2e-87 G SMI1-KNR4 cell-wall
OOONCIOL_00072 2e-76 yokF 3.1.31.1 L RNA catabolic process
OOONCIOL_00075 1.4e-303 yokA L Recombinase
OOONCIOL_00076 2.3e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
OOONCIOL_00077 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
OOONCIOL_00078 1.2e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OOONCIOL_00079 1.4e-66 ypoP K transcriptional
OOONCIOL_00080 1e-96 ypmS S protein conserved in bacteria
OOONCIOL_00081 6.4e-134 ypmR E GDSL-like Lipase/Acylhydrolase
OOONCIOL_00082 7.4e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
OOONCIOL_00083 4.1e-37 ypmP S Protein of unknown function (DUF2535)
OOONCIOL_00084 3.7e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OOONCIOL_00085 1.2e-172 pspF K Transcriptional regulator
OOONCIOL_00086 1.6e-109 hlyIII S protein, Hemolysin III
OOONCIOL_00087 6.1e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OOONCIOL_00088 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OOONCIOL_00089 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OOONCIOL_00090 8.5e-113 ypjP S YpjP-like protein
OOONCIOL_00091 2.6e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
OOONCIOL_00092 1e-75 yphP S Belongs to the UPF0403 family
OOONCIOL_00093 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OOONCIOL_00094 4.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
OOONCIOL_00095 3.1e-99 ypgQ S phosphohydrolase
OOONCIOL_00096 1e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
OOONCIOL_00097 3.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OOONCIOL_00098 1.1e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
OOONCIOL_00099 1e-30 cspD K Cold-shock protein
OOONCIOL_00100 1.3e-11 degR
OOONCIOL_00101 1.2e-36 S Protein of unknown function (DUF2564)
OOONCIOL_00102 1.5e-28 ypeQ S Zinc-finger
OOONCIOL_00103 1.3e-122 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
OOONCIOL_00104 2e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OOONCIOL_00105 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
OOONCIOL_00107 4.5e-163 polA 2.7.7.7 L 5'3' exonuclease
OOONCIOL_00109 2.2e-38 ypbS S Protein of unknown function (DUF2533)
OOONCIOL_00110 0.0 ypbR S Dynamin family
OOONCIOL_00111 1.1e-89 ypbQ S protein conserved in bacteria
OOONCIOL_00112 6.1e-202 bcsA Q Naringenin-chalcone synthase
OOONCIOL_00113 4.5e-106 J Acetyltransferase (GNAT) domain
OOONCIOL_00114 6e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
OOONCIOL_00116 3.9e-22 ydfR S Protein of unknown function (DUF421)
OOONCIOL_00117 2.7e-97 yrdC 3.5.1.19 Q Isochorismatase family
OOONCIOL_00119 4.6e-27 K Helix-turn-helix domain
OOONCIOL_00120 1.4e-22
OOONCIOL_00121 3.4e-86 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
OOONCIOL_00122 2.2e-69 S N-acetylmuramoyl-L-alanine amidase activity
OOONCIOL_00123 1.2e-57 S Pfam:Phage_holin_4_1
OOONCIOL_00125 1.8e-09
OOONCIOL_00126 1.5e-99
OOONCIOL_00127 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
OOONCIOL_00128 4.5e-228 NU Prophage endopeptidase tail
OOONCIOL_00129 5.5e-102 S Phage tail protein
OOONCIOL_00130 0.0 D phage tail tape measure protein
OOONCIOL_00132 3e-81 S Phage tail tube protein
OOONCIOL_00134 7.4e-49 S Bacteriophage HK97-gp10, putative tail-component
OOONCIOL_00135 2.9e-40 S Phage head-tail joining protein
OOONCIOL_00136 3.4e-38 S Phage gp6-like head-tail connector protein
OOONCIOL_00137 1.9e-23
OOONCIOL_00138 1.5e-154 gp36 S capsid protein
OOONCIOL_00139 2.5e-83 S peptidase activity
OOONCIOL_00140 4.2e-170 S Phage portal protein
OOONCIOL_00141 1.2e-300 S Terminase
OOONCIOL_00142 2.2e-77 L phage terminase small subunit
OOONCIOL_00145 2e-20
OOONCIOL_00146 1.4e-17 K Transcriptional regulator
OOONCIOL_00148 3.9e-12 K Transcriptional regulator
OOONCIOL_00150 1.4e-52 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OOONCIOL_00153 6.9e-49
OOONCIOL_00155 4.4e-21 yqaO S Phage-like element PBSX protein XtrA
OOONCIOL_00157 3.5e-60 rusA L Endodeoxyribonuclease RusA
OOONCIOL_00159 6.9e-117 xkdC L IstB-like ATP binding protein
OOONCIOL_00160 5.4e-79 3.1.3.16 L DnaD domain protein
OOONCIOL_00162 1.7e-61 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
OOONCIOL_00163 1.1e-98
OOONCIOL_00167 2e-87
OOONCIOL_00168 5e-43 S Phage regulatory protein Rha (Phage_pRha)
OOONCIOL_00169 1.3e-32
OOONCIOL_00170 2.7e-16 K Helix-turn-helix XRE-family like proteins
OOONCIOL_00171 3.6e-139 L Belongs to the 'phage' integrase family
OOONCIOL_00172 2.2e-235 pbuX F xanthine
OOONCIOL_00173 7.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OOONCIOL_00174 1.3e-290 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OOONCIOL_00175 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
OOONCIOL_00177 6.6e-22 S YpzG-like protein
OOONCIOL_00178 2.7e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OOONCIOL_00179 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OOONCIOL_00180 1.1e-98 ypsA S Belongs to the UPF0398 family
OOONCIOL_00181 9.9e-33 cotD S Inner spore coat protein D
OOONCIOL_00183 8.9e-234 yprB L RNase_H superfamily
OOONCIOL_00184 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
OOONCIOL_00185 1e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
OOONCIOL_00186 2.1e-70 hspX O Belongs to the small heat shock protein (HSP20) family
OOONCIOL_00187 2.1e-49 yppG S YppG-like protein
OOONCIOL_00189 3.3e-11 yppE S Bacterial domain of unknown function (DUF1798)
OOONCIOL_00192 2.8e-187 yppC S Protein of unknown function (DUF2515)
OOONCIOL_00193 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OOONCIOL_00194 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OOONCIOL_00195 5.7e-91 ypoC
OOONCIOL_00196 7.1e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OOONCIOL_00197 3e-130 dnaD L DNA replication protein DnaD
OOONCIOL_00198 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
OOONCIOL_00199 1.1e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
OOONCIOL_00200 5.8e-80 ypmB S protein conserved in bacteria
OOONCIOL_00201 6.7e-23 ypmA S Protein of unknown function (DUF4264)
OOONCIOL_00202 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OOONCIOL_00203 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OOONCIOL_00204 1.4e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OOONCIOL_00205 8.6e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
OOONCIOL_00206 6.2e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OOONCIOL_00207 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OOONCIOL_00208 2.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
OOONCIOL_00209 1.3e-131 bshB1 S proteins, LmbE homologs
OOONCIOL_00210 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
OOONCIOL_00211 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OOONCIOL_00212 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
OOONCIOL_00213 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
OOONCIOL_00214 5e-226 oxdC 4.1.1.2 G Oxalate decarboxylase
OOONCIOL_00215 9.5e-141 ypjB S sporulation protein
OOONCIOL_00216 2.9e-105 ypjA S membrane
OOONCIOL_00217 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
OOONCIOL_00218 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
OOONCIOL_00219 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
OOONCIOL_00220 3.2e-77 ypiF S Protein of unknown function (DUF2487)
OOONCIOL_00221 2.1e-99 ypiB S Belongs to the UPF0302 family
OOONCIOL_00222 2e-233 S COG0457 FOG TPR repeat
OOONCIOL_00223 8.1e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
OOONCIOL_00224 3.3e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
OOONCIOL_00225 1.9e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OOONCIOL_00226 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
OOONCIOL_00227 2.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OOONCIOL_00228 1.7e-114 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
OOONCIOL_00229 1.2e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
OOONCIOL_00230 8.3e-153 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OOONCIOL_00231 4.2e-289 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OOONCIOL_00232 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
OOONCIOL_00233 3.2e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OOONCIOL_00234 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OOONCIOL_00235 1.1e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
OOONCIOL_00236 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
OOONCIOL_00237 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OOONCIOL_00238 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OOONCIOL_00239 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
OOONCIOL_00240 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
OOONCIOL_00241 2.1e-100 folE 3.5.4.16 H GTP cyclohydrolase
OOONCIOL_00242 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OOONCIOL_00243 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OOONCIOL_00244 1.1e-133 yphF
OOONCIOL_00245 3.3e-16 yphE S Protein of unknown function (DUF2768)
OOONCIOL_00246 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OOONCIOL_00247 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OOONCIOL_00248 7.2e-104 yphA
OOONCIOL_00249 4.7e-08 S YpzI-like protein
OOONCIOL_00250 2.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OOONCIOL_00251 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
OOONCIOL_00252 9.5e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OOONCIOL_00253 1.4e-12 S Family of unknown function (DUF5359)
OOONCIOL_00254 1.4e-60 ypfA M Flagellar protein YcgR
OOONCIOL_00255 1.3e-249 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
OOONCIOL_00256 3.9e-159 sleB 3.5.1.28 M Spore cortex-lytic enzyme
OOONCIOL_00257 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
OOONCIOL_00258 1.7e-187 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
OOONCIOL_00259 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OOONCIOL_00260 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OOONCIOL_00261 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
OOONCIOL_00262 1.3e-84 ypbF S Protein of unknown function (DUF2663)
OOONCIOL_00263 1.3e-73 ypbE M Lysin motif
OOONCIOL_00264 4e-99 ypbD S metal-dependent membrane protease
OOONCIOL_00265 3e-270 recQ 3.6.4.12 L DNA helicase
OOONCIOL_00266 1.1e-192 ypbB 5.1.3.1 S protein conserved in bacteria
OOONCIOL_00267 3.6e-41 fer C Ferredoxin
OOONCIOL_00268 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OOONCIOL_00269 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OOONCIOL_00270 5.7e-192 rsiX
OOONCIOL_00271 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
OOONCIOL_00272 0.0 resE 2.7.13.3 T Histidine kinase
OOONCIOL_00273 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOONCIOL_00274 2.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
OOONCIOL_00275 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
OOONCIOL_00276 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
OOONCIOL_00277 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OOONCIOL_00278 1.3e-88 spmB S Spore maturation protein
OOONCIOL_00279 2.3e-102 spmA S Spore maturation protein
OOONCIOL_00280 6.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
OOONCIOL_00281 3.8e-93 ypuI S Protein of unknown function (DUF3907)
OOONCIOL_00282 5.1e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OOONCIOL_00283 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OOONCIOL_00285 1.7e-93 ypuF S Domain of unknown function (DUF309)
OOONCIOL_00286 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OOONCIOL_00287 1.2e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OOONCIOL_00288 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OOONCIOL_00289 1.1e-110 ribE 2.5.1.9 H Riboflavin synthase
OOONCIOL_00290 4.4e-208 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OOONCIOL_00291 6.4e-49 ypuD
OOONCIOL_00292 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OOONCIOL_00293 1.2e-80 ccdC1 O Protein of unknown function (DUF1453)
OOONCIOL_00294 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OOONCIOL_00295 1.9e-153 ypuA S Secreted protein
OOONCIOL_00296 3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OOONCIOL_00297 3.2e-270 spoVAF EG Stage V sporulation protein AF
OOONCIOL_00298 5.2e-110 spoVAEA S stage V sporulation protein
OOONCIOL_00299 5e-57 spoVAEB S stage V sporulation protein
OOONCIOL_00300 1.2e-188 spoVAD I Stage V sporulation protein AD
OOONCIOL_00301 6e-79 spoVAC S stage V sporulation protein AC
OOONCIOL_00302 5.1e-60 spoVAB S Stage V sporulation protein AB
OOONCIOL_00303 1.8e-110 spoVAA S Stage V sporulation protein AA
OOONCIOL_00304 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOONCIOL_00305 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
OOONCIOL_00306 6.6e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
OOONCIOL_00307 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
OOONCIOL_00308 2.7e-146 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OOONCIOL_00309 9.7e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
OOONCIOL_00310 2.8e-165 xerD L recombinase XerD
OOONCIOL_00311 3.7e-37 S Protein of unknown function (DUF4227)
OOONCIOL_00312 1.9e-80 fur P Belongs to the Fur family
OOONCIOL_00313 2.7e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
OOONCIOL_00315 8.6e-34 yqkK
OOONCIOL_00316 5.7e-22
OOONCIOL_00317 6.5e-243 mleA 1.1.1.38 C malic enzyme
OOONCIOL_00318 1.6e-239 mleN C Na H antiporter
OOONCIOL_00319 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
OOONCIOL_00320 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
OOONCIOL_00321 1e-57 ansR K Transcriptional regulator
OOONCIOL_00322 9e-220 yqxK 3.6.4.12 L DNA helicase
OOONCIOL_00323 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
OOONCIOL_00325 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
OOONCIOL_00327 7.6e-174 yqkD S COG1073 Hydrolases of the alpha beta superfamily
OOONCIOL_00328 3.2e-39 yqkC S Protein of unknown function (DUF2552)
OOONCIOL_00329 7.7e-61 yqkB S Belongs to the HesB IscA family
OOONCIOL_00330 7.6e-172 yqkA K GrpB protein
OOONCIOL_00331 9.6e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
OOONCIOL_00332 8.7e-89 yqjY K acetyltransferase
OOONCIOL_00333 6.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OOONCIOL_00334 2.1e-55 S YolD-like protein
OOONCIOL_00336 3.5e-181 yueF S transporter activity
OOONCIOL_00338 5.6e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OOONCIOL_00339 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
OOONCIOL_00340 3.7e-249 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
OOONCIOL_00341 1.2e-138 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
OOONCIOL_00342 2e-172 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
OOONCIOL_00343 6.9e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OOONCIOL_00344 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
OOONCIOL_00345 1.7e-238 pksG 2.3.3.10 I synthase
OOONCIOL_00346 9.8e-219 eryK 1.14.13.154 C Cytochrome P450
OOONCIOL_00347 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
OOONCIOL_00348 0.0 Q Polyketide synthase of type I
OOONCIOL_00349 0.0 pfaA Q Polyketide synthase of type I
OOONCIOL_00350 0.0 pksJ Q Polyketide synthase of type I
OOONCIOL_00351 0.0 Q Polyketide synthase of type I
OOONCIOL_00352 0.0 1.1.1.320 Q Polyketide synthase of type I
OOONCIOL_00353 0.0 pksJ Q Polyketide synthase of type I
OOONCIOL_00354 1.1e-127 IQ reductase
OOONCIOL_00355 1.7e-246 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OOONCIOL_00358 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OOONCIOL_00359 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
OOONCIOL_00360 6e-160 K LysR substrate binding domain
OOONCIOL_00361 7.1e-50 S GlpM protein
OOONCIOL_00362 1.3e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
OOONCIOL_00363 1.8e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OOONCIOL_00364 6.1e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OOONCIOL_00365 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OOONCIOL_00366 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OOONCIOL_00367 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OOONCIOL_00368 2.4e-25 yqzJ
OOONCIOL_00369 1.7e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OOONCIOL_00370 2.4e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
OOONCIOL_00371 1.1e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OOONCIOL_00372 9.4e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
OOONCIOL_00374 3.1e-95 yqjB S protein conserved in bacteria
OOONCIOL_00375 5.3e-170 yqjA S Putative aromatic acid exporter C-terminal domain
OOONCIOL_00376 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OOONCIOL_00377 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
OOONCIOL_00378 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
OOONCIOL_00379 1e-75 yqiW S Belongs to the UPF0403 family
OOONCIOL_00380 2e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OOONCIOL_00381 2e-201 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OOONCIOL_00382 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OOONCIOL_00383 9.5e-162 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OOONCIOL_00384 1e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OOONCIOL_00385 1.6e-205 buk 2.7.2.7 C Belongs to the acetokinase family
OOONCIOL_00386 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
OOONCIOL_00387 2.3e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
OOONCIOL_00388 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
OOONCIOL_00389 3.2e-34 yqzF S Protein of unknown function (DUF2627)
OOONCIOL_00390 2.4e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OOONCIOL_00391 8.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
OOONCIOL_00392 9.4e-203 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
OOONCIOL_00393 2e-203 mmgC I acyl-CoA dehydrogenase
OOONCIOL_00394 1.2e-152 hbdA 1.1.1.157 I Dehydrogenase
OOONCIOL_00395 7e-212 mmgA 2.3.1.9 I Belongs to the thiolase family
OOONCIOL_00396 8.1e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OOONCIOL_00397 8.8e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
OOONCIOL_00398 1.2e-16
OOONCIOL_00399 4.5e-101 ytaF P Probably functions as a manganese efflux pump
OOONCIOL_00400 1.2e-112 K Protein of unknown function (DUF1232)
OOONCIOL_00402 3.5e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
OOONCIOL_00405 2.6e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OOONCIOL_00406 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
OOONCIOL_00407 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
OOONCIOL_00408 4.3e-303 recN L May be involved in recombinational repair of damaged DNA
OOONCIOL_00409 3.9e-78 argR K Regulates arginine biosynthesis genes
OOONCIOL_00410 1.3e-154 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
OOONCIOL_00411 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OOONCIOL_00412 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OOONCIOL_00413 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OOONCIOL_00414 1.3e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OOONCIOL_00415 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OOONCIOL_00416 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OOONCIOL_00417 8.1e-67 yqhY S protein conserved in bacteria
OOONCIOL_00418 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
OOONCIOL_00419 4.6e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OOONCIOL_00420 2.5e-62 spoIIIAH S SpoIIIAH-like protein
OOONCIOL_00421 1.9e-116 spoIIIAG S stage III sporulation protein AG
OOONCIOL_00422 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
OOONCIOL_00423 6.3e-200 spoIIIAE S stage III sporulation protein AE
OOONCIOL_00424 2.5e-41 spoIIIAD S Stage III sporulation protein AD
OOONCIOL_00425 7.6e-29 spoIIIAC S stage III sporulation protein AC
OOONCIOL_00426 1.6e-83 spoIIIAB S Stage III sporulation protein
OOONCIOL_00427 1.6e-171 spoIIIAA S stage III sporulation protein AA
OOONCIOL_00428 1.8e-36 yqhV S Protein of unknown function (DUF2619)
OOONCIOL_00429 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OOONCIOL_00430 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OOONCIOL_00431 3.7e-88 yqhR S Conserved membrane protein YqhR
OOONCIOL_00432 3e-173 yqhQ S Protein of unknown function (DUF1385)
OOONCIOL_00433 9.9e-62 yqhP
OOONCIOL_00434 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
OOONCIOL_00435 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
OOONCIOL_00436 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
OOONCIOL_00437 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
OOONCIOL_00438 1.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OOONCIOL_00439 2.3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OOONCIOL_00440 2.8e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
OOONCIOL_00441 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OOONCIOL_00442 5.5e-152 yqhG S Bacterial protein YqhG of unknown function
OOONCIOL_00443 5.2e-23 sinI S Anti-repressor SinI
OOONCIOL_00444 7.8e-55 sinR K transcriptional
OOONCIOL_00445 1.6e-140 tasA S Cell division protein FtsN
OOONCIOL_00446 3e-70 sipW 3.4.21.89 U Signal peptidase
OOONCIOL_00447 6.1e-120 yqxM
OOONCIOL_00448 1.1e-53 yqzG S Protein of unknown function (DUF3889)
OOONCIOL_00449 2.3e-26 yqzE S YqzE-like protein
OOONCIOL_00450 1e-60 S ComG operon protein 7
OOONCIOL_00451 1.8e-37 comGF U Putative Competence protein ComGF
OOONCIOL_00452 2.6e-20 comGE
OOONCIOL_00453 1.5e-71 gspH NU Tfp pilus assembly protein FimT
OOONCIOL_00454 8.9e-50 comGC U Required for transformation and DNA binding
OOONCIOL_00455 7.8e-183 comGB NU COG1459 Type II secretory pathway, component PulF
OOONCIOL_00456 1.7e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OOONCIOL_00457 1.2e-185 corA P Mg2 transporter protein
OOONCIOL_00458 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OOONCIOL_00459 6.5e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OOONCIOL_00461 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
OOONCIOL_00462 3.1e-37 yqgY S Protein of unknown function (DUF2626)
OOONCIOL_00463 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
OOONCIOL_00464 5.4e-20 yqgW S Protein of unknown function (DUF2759)
OOONCIOL_00465 4.5e-49 yqgV S Thiamine-binding protein
OOONCIOL_00466 1.9e-197 yqgU
OOONCIOL_00467 1.2e-216 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
OOONCIOL_00468 2.2e-179 glcK 2.7.1.2 G Glucokinase
OOONCIOL_00469 8.5e-28 yqgQ S Protein conserved in bacteria
OOONCIOL_00470 1.5e-212 nhaC C Na H antiporter
OOONCIOL_00471 4e-07 yqgO
OOONCIOL_00472 1e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OOONCIOL_00473 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OOONCIOL_00474 1.2e-50 yqzD
OOONCIOL_00475 1.1e-75 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OOONCIOL_00476 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OOONCIOL_00477 6.1e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OOONCIOL_00478 1.4e-153 pstA P Phosphate transport system permease
OOONCIOL_00479 9.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
OOONCIOL_00480 1.4e-156 pstS P Phosphate
OOONCIOL_00481 0.0 pbpA 3.4.16.4 M penicillin-binding protein
OOONCIOL_00482 3.4e-228 yqgE EGP Major facilitator superfamily
OOONCIOL_00483 6.9e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
OOONCIOL_00484 4.9e-71 yqgC S protein conserved in bacteria
OOONCIOL_00485 2.4e-128 yqgB S Protein of unknown function (DUF1189)
OOONCIOL_00486 3.1e-47 yqfZ M LysM domain
OOONCIOL_00487 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OOONCIOL_00488 2.3e-52 yqfX S membrane
OOONCIOL_00489 4.2e-109 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
OOONCIOL_00490 2.9e-72 zur P Belongs to the Fur family
OOONCIOL_00491 5.3e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OOONCIOL_00492 1.3e-35 yqfT S Protein of unknown function (DUF2624)
OOONCIOL_00493 2.8e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OOONCIOL_00494 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OOONCIOL_00495 3.7e-43 yqfQ S YqfQ-like protein
OOONCIOL_00496 6.5e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OOONCIOL_00497 1.3e-207 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OOONCIOL_00498 2.9e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
OOONCIOL_00499 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
OOONCIOL_00500 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OOONCIOL_00501 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OOONCIOL_00502 6.1e-88 yaiI S Belongs to the UPF0178 family
OOONCIOL_00503 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OOONCIOL_00504 4.5e-112 ccpN K CBS domain
OOONCIOL_00505 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
OOONCIOL_00506 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
OOONCIOL_00507 1e-142 recO L Involved in DNA repair and RecF pathway recombination
OOONCIOL_00508 1.8e-16 S YqzL-like protein
OOONCIOL_00509 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OOONCIOL_00510 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OOONCIOL_00511 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
OOONCIOL_00512 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OOONCIOL_00513 0.0 yqfF S membrane-associated HD superfamily hydrolase
OOONCIOL_00514 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
OOONCIOL_00515 5.7e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
OOONCIOL_00516 9.3e-46 yqfC S sporulation protein YqfC
OOONCIOL_00517 1.9e-42 yqfB
OOONCIOL_00518 3.8e-118 yqfA S UPF0365 protein
OOONCIOL_00519 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
OOONCIOL_00520 8e-68 yqeY S Yqey-like protein
OOONCIOL_00521 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OOONCIOL_00522 5.6e-156 yqeW P COG1283 Na phosphate symporter
OOONCIOL_00523 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
OOONCIOL_00524 5.1e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OOONCIOL_00525 6.6e-173 prmA J Methylates ribosomal protein L11
OOONCIOL_00526 1.9e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OOONCIOL_00527 0.0 dnaK O Heat shock 70 kDa protein
OOONCIOL_00528 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OOONCIOL_00529 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OOONCIOL_00530 1.2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
OOONCIOL_00531 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OOONCIOL_00532 2.5e-53 yqxA S Protein of unknown function (DUF3679)
OOONCIOL_00533 1.5e-217 spoIIP M stage II sporulation protein P
OOONCIOL_00534 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OOONCIOL_00535 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
OOONCIOL_00536 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
OOONCIOL_00537 0.0 comEC S Competence protein ComEC
OOONCIOL_00538 8e-105 comEB 3.5.4.12 F ComE operon protein 2
OOONCIOL_00539 6.2e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
OOONCIOL_00540 3.8e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OOONCIOL_00541 3.2e-138 yqeM Q Methyltransferase
OOONCIOL_00542 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OOONCIOL_00543 1.6e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
OOONCIOL_00544 2.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OOONCIOL_00545 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
OOONCIOL_00546 2.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OOONCIOL_00547 1.3e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
OOONCIOL_00548 7.6e-94 yqeG S hydrolase of the HAD superfamily
OOONCIOL_00550 2.5e-138 yqeF E GDSL-like Lipase/Acylhydrolase
OOONCIOL_00551 3.8e-139 3.5.1.104 G Polysaccharide deacetylase
OOONCIOL_00552 8e-106 yqeD S SNARE associated Golgi protein
OOONCIOL_00553 1.8e-213 EGP Major facilitator Superfamily
OOONCIOL_00554 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOONCIOL_00555 7.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
OOONCIOL_00556 3.6e-91 K Transcriptional regulator PadR-like family
OOONCIOL_00557 2.6e-147 ydeE K AraC family transcriptional regulator
OOONCIOL_00558 1.7e-96 adk 2.7.4.3 F adenylate kinase activity
OOONCIOL_00559 5.6e-23 yyaR K acetyltransferase
OOONCIOL_00560 9.9e-218 tetL EGP Major facilitator Superfamily
OOONCIOL_00562 1.2e-56 S SMI1-KNR4 cell-wall
OOONCIOL_00563 1.9e-118 L nucleic acid phosphodiester bond hydrolysis
OOONCIOL_00564 1.2e-39
OOONCIOL_00566 8.2e-20 S Calcineurin-like phosphoesterase
OOONCIOL_00568 1.1e-59 S Abortive infection C-terminus
OOONCIOL_00571 6.7e-24
OOONCIOL_00572 1.1e-81 yyaR K Acetyltransferase (GNAT) domain
OOONCIOL_00573 1.5e-91 yrdA S DinB family
OOONCIOL_00575 5.5e-144 S hydrolase
OOONCIOL_00576 4.3e-71 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
OOONCIOL_00577 1.4e-52 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
OOONCIOL_00578 1.7e-128 glvR K Helix-turn-helix domain, rpiR family
OOONCIOL_00579 3.8e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
OOONCIOL_00580 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
OOONCIOL_00581 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
OOONCIOL_00582 4.5e-182 romA S Beta-lactamase superfamily domain
OOONCIOL_00583 8.9e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OOONCIOL_00584 5.9e-163 yybE K Transcriptional regulator
OOONCIOL_00585 3.2e-212 ynfM EGP Major facilitator Superfamily
OOONCIOL_00586 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OOONCIOL_00587 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
OOONCIOL_00588 7.1e-79 yrhH Q methyltransferase
OOONCIOL_00590 8e-143 focA P Formate nitrite
OOONCIOL_00591 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
OOONCIOL_00592 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
OOONCIOL_00593 7e-81 yrhD S Protein of unknown function (DUF1641)
OOONCIOL_00594 5.1e-34 yrhC S YrhC-like protein
OOONCIOL_00595 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OOONCIOL_00596 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
OOONCIOL_00597 3.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OOONCIOL_00598 2.3e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
OOONCIOL_00599 1.6e-26 yrzA S Protein of unknown function (DUF2536)
OOONCIOL_00600 8.1e-70 yrrS S Protein of unknown function (DUF1510)
OOONCIOL_00601 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
OOONCIOL_00602 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OOONCIOL_00603 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
OOONCIOL_00604 6.1e-246 yegQ O COG0826 Collagenase and related proteases
OOONCIOL_00605 2.9e-173 yegQ O Peptidase U32
OOONCIOL_00606 9.5e-118 yrrM 2.1.1.104 S O-methyltransferase
OOONCIOL_00607 4.1e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OOONCIOL_00608 7.1e-46 yrzB S Belongs to the UPF0473 family
OOONCIOL_00609 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OOONCIOL_00610 8.5e-41 yrzL S Belongs to the UPF0297 family
OOONCIOL_00611 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OOONCIOL_00612 3.5e-162 yrrI S AI-2E family transporter
OOONCIOL_00613 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OOONCIOL_00614 3.6e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
OOONCIOL_00615 1.2e-107 gluC P ABC transporter
OOONCIOL_00616 4.9e-106 glnP P ABC transporter
OOONCIOL_00617 2.1e-08 S Protein of unknown function (DUF3918)
OOONCIOL_00618 2.9e-30 yrzR
OOONCIOL_00619 3.4e-82 yrrD S protein conserved in bacteria
OOONCIOL_00620 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OOONCIOL_00621 1.7e-18 S COG0457 FOG TPR repeat
OOONCIOL_00622 3.2e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OOONCIOL_00623 1.3e-210 iscS 2.8.1.7 E Cysteine desulfurase
OOONCIOL_00624 7.8e-64 cymR K Transcriptional regulator
OOONCIOL_00625 1.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
OOONCIOL_00626 1.4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
OOONCIOL_00627 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OOONCIOL_00628 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
OOONCIOL_00631 4.2e-273 lytH 3.5.1.28 M COG3103 SH3 domain protein
OOONCIOL_00632 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OOONCIOL_00633 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OOONCIOL_00634 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OOONCIOL_00635 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OOONCIOL_00636 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
OOONCIOL_00637 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
OOONCIOL_00638 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OOONCIOL_00639 8.5e-50 yrzD S Post-transcriptional regulator
OOONCIOL_00640 4.6e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OOONCIOL_00641 9.5e-110 yrbG S membrane
OOONCIOL_00642 2.4e-60 yrzE S Protein of unknown function (DUF3792)
OOONCIOL_00643 2.5e-37 yajC U Preprotein translocase subunit YajC
OOONCIOL_00644 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OOONCIOL_00645 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OOONCIOL_00646 1.6e-20 yrzS S Protein of unknown function (DUF2905)
OOONCIOL_00647 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OOONCIOL_00648 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OOONCIOL_00649 1.5e-91 bofC S BofC C-terminal domain
OOONCIOL_00651 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OOONCIOL_00652 2.1e-115 safA M spore coat assembly protein SafA
OOONCIOL_00653 2.7e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OOONCIOL_00654 4.9e-151 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
OOONCIOL_00655 1.9e-294 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
OOONCIOL_00656 9.5e-222 nifS 2.8.1.7 E Cysteine desulfurase
OOONCIOL_00657 1.3e-93 niaR S small molecule binding protein (contains 3H domain)
OOONCIOL_00658 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
OOONCIOL_00659 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
OOONCIOL_00660 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OOONCIOL_00661 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
OOONCIOL_00662 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OOONCIOL_00663 3.2e-56 ysxB J ribosomal protein
OOONCIOL_00664 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
OOONCIOL_00665 1.2e-160 spoIVFB S Stage IV sporulation protein
OOONCIOL_00666 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
OOONCIOL_00667 2.3e-142 minD D Belongs to the ParA family
OOONCIOL_00668 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OOONCIOL_00669 5.4e-84 mreD M shape-determining protein
OOONCIOL_00670 3.6e-157 mreC M Involved in formation and maintenance of cell shape
OOONCIOL_00671 4e-184 mreB D Rod shape-determining protein MreB
OOONCIOL_00672 5.3e-127 radC E Belongs to the UPF0758 family
OOONCIOL_00673 9.5e-98 maf D septum formation protein Maf
OOONCIOL_00674 6.3e-137 spoIIB S Sporulation related domain
OOONCIOL_00675 2.5e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
OOONCIOL_00676 8.1e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OOONCIOL_00677 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OOONCIOL_00678 2.1e-25
OOONCIOL_00679 8.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OOONCIOL_00680 6.7e-228 spoVID M stage VI sporulation protein D
OOONCIOL_00681 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OOONCIOL_00682 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
OOONCIOL_00683 6.2e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OOONCIOL_00684 3.5e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
OOONCIOL_00685 1e-145 hemX O cytochrome C
OOONCIOL_00686 7.7e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OOONCIOL_00687 3.8e-87 ysxD
OOONCIOL_00688 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
OOONCIOL_00689 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OOONCIOL_00690 3e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
OOONCIOL_00691 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OOONCIOL_00692 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OOONCIOL_00693 1e-187 ysoA H Tetratricopeptide repeat
OOONCIOL_00694 3.1e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OOONCIOL_00695 4.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OOONCIOL_00696 1.1e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
OOONCIOL_00697 4.6e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OOONCIOL_00698 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OOONCIOL_00699 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
OOONCIOL_00700 0.0 ilvB 2.2.1.6 E Acetolactate synthase
OOONCIOL_00703 9e-42 pinR3 L Resolvase, N terminal domain
OOONCIOL_00704 1.1e-38 pinR3 L Resolvase, N terminal domain
OOONCIOL_00705 1.6e-112 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
OOONCIOL_00706 3.9e-249 hsdM 2.1.1.72 L type I restriction-modification system
OOONCIOL_00707 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
OOONCIOL_00711 5.9e-91 ysnB S Phosphoesterase
OOONCIOL_00712 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OOONCIOL_00713 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OOONCIOL_00714 5.3e-198 gerM S COG5401 Spore germination protein
OOONCIOL_00715 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OOONCIOL_00716 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
OOONCIOL_00717 2e-30 gerE K Transcriptional regulator
OOONCIOL_00718 7.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
OOONCIOL_00719 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OOONCIOL_00720 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OOONCIOL_00721 4.8e-108 sdhC C succinate dehydrogenase
OOONCIOL_00722 2e-79 yslB S Protein of unknown function (DUF2507)
OOONCIOL_00723 1.7e-213 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OOONCIOL_00724 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OOONCIOL_00725 2.5e-52 trxA O Belongs to the thioredoxin family
OOONCIOL_00726 5.6e-299 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
OOONCIOL_00727 1.6e-177 etfA C Electron transfer flavoprotein
OOONCIOL_00728 1.7e-137 etfB C Electron transfer flavoprotein
OOONCIOL_00729 1.9e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OOONCIOL_00730 2.7e-103 fadR K Transcriptional regulator
OOONCIOL_00731 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OOONCIOL_00732 1.6e-115 ywbB S Protein of unknown function (DUF2711)
OOONCIOL_00733 4.7e-67 yshE S membrane
OOONCIOL_00734 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OOONCIOL_00735 0.0 polX L COG1796 DNA polymerase IV (family X)
OOONCIOL_00736 3.6e-83 cvpA S membrane protein, required for colicin V production
OOONCIOL_00737 1.2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OOONCIOL_00738 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OOONCIOL_00739 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OOONCIOL_00740 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OOONCIOL_00741 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OOONCIOL_00742 2e-32 sspI S Belongs to the SspI family
OOONCIOL_00743 2.7e-202 ysfB KT regulator
OOONCIOL_00744 1.6e-258 glcD 1.1.3.15 C FAD binding domain
OOONCIOL_00745 2e-255 glcF C Glycolate oxidase
OOONCIOL_00746 0.0 cstA T Carbon starvation protein
OOONCIOL_00747 3.9e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
OOONCIOL_00748 1.2e-144 araQ G transport system permease
OOONCIOL_00749 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
OOONCIOL_00750 2.9e-251 araN G carbohydrate transport
OOONCIOL_00751 1.2e-224 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
OOONCIOL_00752 1.7e-140 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
OOONCIOL_00753 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
OOONCIOL_00754 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
OOONCIOL_00755 4e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
OOONCIOL_00756 6.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OOONCIOL_00757 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
OOONCIOL_00758 1.9e-65 ysdB S Sigma-w pathway protein YsdB
OOONCIOL_00759 2.6e-42 ysdA S Membrane
OOONCIOL_00760 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OOONCIOL_00761 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OOONCIOL_00762 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OOONCIOL_00763 5.4e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OOONCIOL_00764 2.9e-38 lrgA S effector of murein hydrolase LrgA
OOONCIOL_00765 5.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
OOONCIOL_00766 0.0 lytS 2.7.13.3 T Histidine kinase
OOONCIOL_00767 3.9e-150 ysaA S HAD-hyrolase-like
OOONCIOL_00768 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OOONCIOL_00769 6.7e-153 ytxC S YtxC-like family
OOONCIOL_00770 2.1e-106 ytxB S SNARE associated Golgi protein
OOONCIOL_00771 9.5e-172 dnaI L Primosomal protein DnaI
OOONCIOL_00772 3.1e-251 dnaB L Membrane attachment protein
OOONCIOL_00773 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OOONCIOL_00774 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OOONCIOL_00775 2.2e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OOONCIOL_00776 2e-67 ytcD K Transcriptional regulator
OOONCIOL_00777 4.5e-206 ytbD EGP Major facilitator Superfamily
OOONCIOL_00778 1.7e-159 ytbE S reductase
OOONCIOL_00779 2e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OOONCIOL_00780 6.2e-106 ytaF P Probably functions as a manganese efflux pump
OOONCIOL_00781 9.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OOONCIOL_00782 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OOONCIOL_00783 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
OOONCIOL_00784 1.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOONCIOL_00785 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
OOONCIOL_00786 1.2e-241 icd 1.1.1.42 C isocitrate
OOONCIOL_00787 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
OOONCIOL_00788 6.1e-46 yjdF S Protein of unknown function (DUF2992)
OOONCIOL_00789 1.1e-72 yeaL S membrane
OOONCIOL_00790 2.4e-193 ytvI S sporulation integral membrane protein YtvI
OOONCIOL_00791 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
OOONCIOL_00792 7.5e-295 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OOONCIOL_00793 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OOONCIOL_00794 5.3e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
OOONCIOL_00795 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OOONCIOL_00796 2.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
OOONCIOL_00797 0.0 dnaE 2.7.7.7 L DNA polymerase
OOONCIOL_00798 3.2e-56 ytrH S Sporulation protein YtrH
OOONCIOL_00799 4.3e-86 ytrI
OOONCIOL_00800 5.8e-23
OOONCIOL_00801 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
OOONCIOL_00802 1.5e-46 ytpI S YtpI-like protein
OOONCIOL_00803 1.6e-236 ytoI K transcriptional regulator containing CBS domains
OOONCIOL_00804 1.3e-128 ytkL S Belongs to the UPF0173 family
OOONCIOL_00805 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOONCIOL_00807 2.7e-263 argH 4.3.2.1 E argininosuccinate lyase
OOONCIOL_00808 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
OOONCIOL_00809 6.8e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
OOONCIOL_00810 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OOONCIOL_00811 9.1e-181 ytxK 2.1.1.72 L DNA methylase
OOONCIOL_00812 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OOONCIOL_00813 1.6e-60 ytfJ S Sporulation protein YtfJ
OOONCIOL_00814 1e-93 ytfI S Protein of unknown function (DUF2953)
OOONCIOL_00815 1e-87 yteJ S RDD family
OOONCIOL_00816 6.4e-182 sppA OU signal peptide peptidase SppA
OOONCIOL_00817 8.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OOONCIOL_00818 3.3e-310 ytcJ S amidohydrolase
OOONCIOL_00819 4.2e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OOONCIOL_00820 3.9e-31 sspB S spore protein
OOONCIOL_00821 5.6e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OOONCIOL_00822 1.3e-207 iscS2 2.8.1.7 E Cysteine desulfurase
OOONCIOL_00823 2.6e-239 braB E Component of the transport system for branched-chain amino acids
OOONCIOL_00824 2.1e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OOONCIOL_00825 3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
OOONCIOL_00826 1e-108 yttP K Transcriptional regulator
OOONCIOL_00827 4.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
OOONCIOL_00828 1e-280 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
OOONCIOL_00829 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OOONCIOL_00830 2.3e-254 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OOONCIOL_00831 1.2e-100 yokH G SMI1 / KNR4 family
OOONCIOL_00832 3.9e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OOONCIOL_00833 2.5e-09
OOONCIOL_00834 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
OOONCIOL_00836 3e-136 E GDSL-like Lipase/Acylhydrolase family
OOONCIOL_00837 1.1e-148 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OOONCIOL_00838 2.8e-148 K Transcriptional regulator
OOONCIOL_00839 4.4e-124 azlC E AzlC protein
OOONCIOL_00840 1.6e-46 azlD S Branched-chain amino acid transport protein (AzlD)
OOONCIOL_00841 4.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OOONCIOL_00842 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OOONCIOL_00843 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
OOONCIOL_00844 6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
OOONCIOL_00845 1.1e-228 acuC BQ histone deacetylase
OOONCIOL_00846 3.7e-120 motS N Flagellar motor protein
OOONCIOL_00847 6.6e-145 motA N flagellar motor
OOONCIOL_00848 6.4e-182 ccpA K catabolite control protein A
OOONCIOL_00849 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
OOONCIOL_00850 8.5e-43 ytxJ O Protein of unknown function (DUF2847)
OOONCIOL_00851 1.7e-16 ytxH S COG4980 Gas vesicle protein
OOONCIOL_00852 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OOONCIOL_00853 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OOONCIOL_00854 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
OOONCIOL_00855 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OOONCIOL_00856 3.7e-148 ytpQ S Belongs to the UPF0354 family
OOONCIOL_00857 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OOONCIOL_00858 3.2e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
OOONCIOL_00859 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
OOONCIOL_00860 1.7e-51 ytzB S small secreted protein
OOONCIOL_00861 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
OOONCIOL_00862 2.1e-162 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
OOONCIOL_00863 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OOONCIOL_00864 3.5e-45 ytzH S YtzH-like protein
OOONCIOL_00865 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
OOONCIOL_00866 9.8e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
OOONCIOL_00867 3.5e-166 ytlQ
OOONCIOL_00868 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OOONCIOL_00869 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OOONCIOL_00870 5.2e-267 pepV 3.5.1.18 E Dipeptidase
OOONCIOL_00871 1.3e-227 pbuO S permease
OOONCIOL_00872 4.3e-214 ythQ U Bacterial ABC transporter protein EcsB
OOONCIOL_00873 3.7e-128 ythP V ABC transporter
OOONCIOL_00874 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
OOONCIOL_00875 2.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OOONCIOL_00876 3.8e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OOONCIOL_00877 5.7e-236 ytfP S HI0933-like protein
OOONCIOL_00878 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
OOONCIOL_00879 9e-26 yteV S Sporulation protein Cse60
OOONCIOL_00880 2.8e-185 msmR K Transcriptional regulator
OOONCIOL_00881 3.7e-243 msmE G Bacterial extracellular solute-binding protein
OOONCIOL_00882 1.6e-168 amyD G Binding-protein-dependent transport system inner membrane component
OOONCIOL_00883 1.8e-142 amyC P ABC transporter (permease)
OOONCIOL_00884 1e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
OOONCIOL_00885 1.7e-84 M Acetyltransferase (GNAT) domain
OOONCIOL_00886 3.6e-51 ytwF P Sulfurtransferase
OOONCIOL_00887 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OOONCIOL_00888 1.2e-52 ytvB S Protein of unknown function (DUF4257)
OOONCIOL_00889 3.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
OOONCIOL_00890 1.8e-207 yttB EGP Major facilitator Superfamily
OOONCIOL_00891 1.2e-121 ywaF S Integral membrane protein
OOONCIOL_00892 0.0 bceB V ABC transporter (permease)
OOONCIOL_00893 4.9e-134 bceA V ABC transporter, ATP-binding protein
OOONCIOL_00894 4.8e-177 T PhoQ Sensor
OOONCIOL_00895 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOONCIOL_00896 1.8e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
OOONCIOL_00897 2.2e-125 ytrE V ABC transporter, ATP-binding protein
OOONCIOL_00898 4e-152
OOONCIOL_00899 4.1e-173 P ABC-2 family transporter protein
OOONCIOL_00900 2e-164 S ABC-2 family transporter protein
OOONCIOL_00901 7.1e-161 ytrB P abc transporter atp-binding protein
OOONCIOL_00902 3.9e-66 ytrA K GntR family transcriptional regulator
OOONCIOL_00904 1.3e-39 ytzC S Protein of unknown function (DUF2524)
OOONCIOL_00905 1.1e-189 yhcC S Fe-S oxidoreductase
OOONCIOL_00906 2.8e-105 ytqB J Putative rRNA methylase
OOONCIOL_00908 1.5e-141 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
OOONCIOL_00909 7.1e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
OOONCIOL_00910 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
OOONCIOL_00911 3.9e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OOONCIOL_00912 1.1e-259 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
OOONCIOL_00913 0.0 asnB 6.3.5.4 E Asparagine synthase
OOONCIOL_00914 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OOONCIOL_00915 1.2e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OOONCIOL_00916 1.6e-38 ytmB S Protein of unknown function (DUF2584)
OOONCIOL_00917 4.4e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
OOONCIOL_00918 8.9e-184 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OOONCIOL_00919 3.2e-144 ytlC P ABC transporter
OOONCIOL_00920 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OOONCIOL_00921 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
OOONCIOL_00922 5e-61 ytkC S Bacteriophage holin family
OOONCIOL_00923 7.8e-76 dps P Belongs to the Dps family
OOONCIOL_00925 5.1e-75 ytkA S YtkA-like
OOONCIOL_00926 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OOONCIOL_00927 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
OOONCIOL_00928 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OOONCIOL_00929 7.9e-41 rpmE2 J Ribosomal protein L31
OOONCIOL_00930 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
OOONCIOL_00931 1.5e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
OOONCIOL_00932 2e-23 S Domain of Unknown Function (DUF1540)
OOONCIOL_00933 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
OOONCIOL_00934 4.1e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OOONCIOL_00935 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OOONCIOL_00936 3.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
OOONCIOL_00937 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OOONCIOL_00938 2.7e-271 menF 5.4.4.2 HQ Isochorismate synthase
OOONCIOL_00939 7e-130 dksA T COG1734 DnaK suppressor protein
OOONCIOL_00940 5.8e-77 tspO T membrane
OOONCIOL_00949 7.8e-08
OOONCIOL_00950 1.3e-09
OOONCIOL_00957 1.6e-08
OOONCIOL_00962 3.4e-39 S COG NOG14552 non supervised orthologous group
OOONCIOL_00963 2.8e-97 thiT S Thiamine transporter protein (Thia_YuaJ)
OOONCIOL_00964 5e-178 yuaG 3.4.21.72 S protein conserved in bacteria
OOONCIOL_00965 1.6e-83 yuaF OU Membrane protein implicated in regulation of membrane protease activity
OOONCIOL_00966 2e-72 yuaE S DinB superfamily
OOONCIOL_00967 2.5e-109 yuaD S MOSC domain
OOONCIOL_00968 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
OOONCIOL_00969 3.2e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
OOONCIOL_00970 8.6e-96 yuaC K Belongs to the GbsR family
OOONCIOL_00971 7.9e-94 yuaB
OOONCIOL_00972 1.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
OOONCIOL_00973 9e-145 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OOONCIOL_00974 2.7e-216 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OOONCIOL_00975 1.4e-118 G Cupin
OOONCIOL_00976 3.4e-52 yjcN
OOONCIOL_00980 2.7e-108 S Aspartate phosphatase response regulator
OOONCIOL_00981 8e-15
OOONCIOL_00982 6.8e-34
OOONCIOL_00984 5.7e-144 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
OOONCIOL_00985 2.2e-194 yubA S transporter activity
OOONCIOL_00986 3.9e-184 ygjR S Oxidoreductase
OOONCIOL_00987 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
OOONCIOL_00988 2.6e-235 mcpA NT chemotaxis protein
OOONCIOL_00989 6e-224 mcpA NT chemotaxis protein
OOONCIOL_00990 5.8e-235 mcpA NT chemotaxis protein
OOONCIOL_00991 8.1e-221 mcpA NT chemotaxis protein
OOONCIOL_00992 2.2e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
OOONCIOL_00993 1.4e-40
OOONCIOL_00994 2.3e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OOONCIOL_00995 2e-73 yugU S Uncharacterised protein family UPF0047
OOONCIOL_00996 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
OOONCIOL_00997 2.5e-231 yugS S COG1253 Hemolysins and related proteins containing CBS domains
OOONCIOL_00998 8.3e-117 yugP S Zn-dependent protease
OOONCIOL_00999 3.4e-18
OOONCIOL_01000 6.7e-27 mstX S Membrane-integrating protein Mistic
OOONCIOL_01001 2e-180 yugO P COG1226 Kef-type K transport systems
OOONCIOL_01002 7e-71 yugN S YugN-like family
OOONCIOL_01004 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
OOONCIOL_01005 1.6e-45 S NADPH-dependent FMN reductase
OOONCIOL_01006 5.5e-118 ycaC Q Isochorismatase family
OOONCIOL_01007 1.8e-228 yugK C Dehydrogenase
OOONCIOL_01008 1.4e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
OOONCIOL_01009 1.8e-34 yuzA S Domain of unknown function (DUF378)
OOONCIOL_01010 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
OOONCIOL_01011 1.6e-208 yugH 2.6.1.1 E Aminotransferase
OOONCIOL_01012 2e-83 alaR K Transcriptional regulator
OOONCIOL_01013 5.5e-155 yugF I Hydrolase
OOONCIOL_01014 1.4e-40 yugE S Domain of unknown function (DUF1871)
OOONCIOL_01015 1e-223 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
OOONCIOL_01016 8.9e-229 T PhoQ Sensor
OOONCIOL_01017 7.7e-67 kapB G Kinase associated protein B
OOONCIOL_01018 4e-118 kapD L the KinA pathway to sporulation
OOONCIOL_01019 4.5e-185 yuxJ EGP Major facilitator Superfamily
OOONCIOL_01020 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
OOONCIOL_01021 2.2e-72 yuxK S protein conserved in bacteria
OOONCIOL_01022 9.3e-74 yufK S Family of unknown function (DUF5366)
OOONCIOL_01023 1.4e-292 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OOONCIOL_01024 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
OOONCIOL_01025 3.9e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
OOONCIOL_01026 2.3e-284 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
OOONCIOL_01027 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
OOONCIOL_01028 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
OOONCIOL_01029 2.3e-12
OOONCIOL_01030 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OOONCIOL_01031 1.3e-67 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OOONCIOL_01032 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OOONCIOL_01033 3.4e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OOONCIOL_01034 8.5e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OOONCIOL_01035 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OOONCIOL_01036 2.6e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
OOONCIOL_01037 1.1e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
OOONCIOL_01038 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OOONCIOL_01039 2.7e-308 comP 2.7.13.3 T Histidine kinase
OOONCIOL_01041 4.1e-93 comQ H Polyprenyl synthetase
OOONCIOL_01044 1.4e-51 yuzC
OOONCIOL_01045 3.8e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
OOONCIOL_01046 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OOONCIOL_01047 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
OOONCIOL_01048 7.2e-68 yueI S Protein of unknown function (DUF1694)
OOONCIOL_01049 2.8e-38 yueH S YueH-like protein
OOONCIOL_01050 6.4e-34 yueG S Spore germination protein gerPA/gerPF
OOONCIOL_01051 3.6e-186 yueF S transporter activity
OOONCIOL_01052 1.6e-22 S Protein of unknown function (DUF2642)
OOONCIOL_01053 8.3e-96 yueE S phosphohydrolase
OOONCIOL_01054 7.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOONCIOL_01055 8.5e-76 yueC S Family of unknown function (DUF5383)
OOONCIOL_01056 0.0 esaA S type VII secretion protein EsaA
OOONCIOL_01057 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OOONCIOL_01058 1.3e-203 essB S WXG100 protein secretion system (Wss), protein YukC
OOONCIOL_01059 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
OOONCIOL_01060 3.3e-46 esxA S Belongs to the WXG100 family
OOONCIOL_01061 4.2e-228 yukF QT Transcriptional regulator
OOONCIOL_01062 8.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
OOONCIOL_01063 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
OOONCIOL_01064 1.1e-33 mbtH S MbtH-like protein
OOONCIOL_01065 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOONCIOL_01066 3.6e-171 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
OOONCIOL_01067 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
OOONCIOL_01068 5.4e-220 entC 5.4.4.2 HQ Isochorismate synthase
OOONCIOL_01069 1.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OOONCIOL_01070 1.2e-163 besA S Putative esterase
OOONCIOL_01071 3.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
OOONCIOL_01072 1.5e-101 bioY S Biotin biosynthesis protein
OOONCIOL_01073 2.6e-207 yuiF S antiporter
OOONCIOL_01074 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OOONCIOL_01075 1.6e-77 yuiD S protein conserved in bacteria
OOONCIOL_01076 2.7e-117 yuiC S protein conserved in bacteria
OOONCIOL_01077 9.9e-28 yuiB S Putative membrane protein
OOONCIOL_01078 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
OOONCIOL_01079 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
OOONCIOL_01081 3.9e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OOONCIOL_01082 4.8e-29
OOONCIOL_01083 3.8e-69 CP Membrane
OOONCIOL_01084 1.5e-121 V ABC transporter
OOONCIOL_01086 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
OOONCIOL_01088 2.3e-26 K helix_turn_helix, mercury resistance
OOONCIOL_01089 1.6e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
OOONCIOL_01090 1.1e-62 erpA S Belongs to the HesB IscA family
OOONCIOL_01091 1.4e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OOONCIOL_01092 5e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OOONCIOL_01093 2.4e-39 yuzB S Belongs to the UPF0349 family
OOONCIOL_01094 2.7e-207 yutJ 1.6.99.3 C NADH dehydrogenase
OOONCIOL_01095 1.1e-53 yuzD S protein conserved in bacteria
OOONCIOL_01096 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
OOONCIOL_01097 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
OOONCIOL_01098 6.4e-168 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OOONCIOL_01099 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OOONCIOL_01100 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
OOONCIOL_01101 3e-195 yutH S Spore coat protein
OOONCIOL_01102 3.3e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OOONCIOL_01103 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OOONCIOL_01104 6.8e-72 yutE S Protein of unknown function DUF86
OOONCIOL_01105 1.7e-47 yutD S protein conserved in bacteria
OOONCIOL_01106 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OOONCIOL_01107 6.6e-192 lytH M Peptidase, M23
OOONCIOL_01108 2.5e-130 yunB S Sporulation protein YunB (Spo_YunB)
OOONCIOL_01109 6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OOONCIOL_01110 5.1e-145 yunE S membrane transporter protein
OOONCIOL_01111 1.5e-168 yunF S Protein of unknown function DUF72
OOONCIOL_01112 3.7e-60 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
OOONCIOL_01113 1.7e-262 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
OOONCIOL_01114 4.4e-302 pucR QT COG2508 Regulator of polyketide synthase expression
OOONCIOL_01115 7.9e-21 yqbD 2.1.1.72 L Putative phage serine protease XkdF
OOONCIOL_01116 6.6e-20
OOONCIOL_01118 1.6e-211 blt EGP Major facilitator Superfamily
OOONCIOL_01119 5.6e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
OOONCIOL_01120 3.6e-235 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OOONCIOL_01121 2.1e-165 bsn L Ribonuclease
OOONCIOL_01122 5.4e-206 msmX P Belongs to the ABC transporter superfamily
OOONCIOL_01123 1.2e-134 yurK K UTRA
OOONCIOL_01124 1.5e-160 yurL 2.7.1.218 G pfkB family carbohydrate kinase
OOONCIOL_01125 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
OOONCIOL_01126 9.8e-158 yurN G Binding-protein-dependent transport system inner membrane component
OOONCIOL_01127 1.5e-244 yurO G COG1653 ABC-type sugar transport system, periplasmic component
OOONCIOL_01128 2.7e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
OOONCIOL_01129 1.9e-164 K helix_turn_helix, mercury resistance
OOONCIOL_01131 7e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
OOONCIOL_01132 1.4e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
OOONCIOL_01133 3.4e-121 Q ubiE/COQ5 methyltransferase family
OOONCIOL_01134 2e-39 yncE S Protein of unknown function (DUF2691)
OOONCIOL_01135 2.5e-25 yncE S Protein of unknown function (DUF2691)
OOONCIOL_01136 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
OOONCIOL_01137 8.7e-270 sufB O FeS cluster assembly
OOONCIOL_01138 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
OOONCIOL_01139 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OOONCIOL_01140 1.2e-244 sufD O assembly protein SufD
OOONCIOL_01141 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
OOONCIOL_01142 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OOONCIOL_01143 3e-145 metQ P Belongs to the NlpA lipoprotein family
OOONCIOL_01144 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
OOONCIOL_01145 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OOONCIOL_01146 1.5e-56 yusD S SCP-2 sterol transfer family
OOONCIOL_01147 6.2e-54 yusE CO Thioredoxin
OOONCIOL_01148 4.9e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
OOONCIOL_01149 3.7e-40 yusG S Protein of unknown function (DUF2553)
OOONCIOL_01150 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
OOONCIOL_01151 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
OOONCIOL_01152 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
OOONCIOL_01153 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
OOONCIOL_01154 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
OOONCIOL_01156 1.9e-164 fadM E Proline dehydrogenase
OOONCIOL_01157 6.7e-43
OOONCIOL_01158 1.1e-53 yusN M Coat F domain
OOONCIOL_01159 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
OOONCIOL_01160 1.4e-287 yusP P Major facilitator superfamily
OOONCIOL_01161 1e-154 ywbI2 K Transcriptional regulator
OOONCIOL_01162 1.6e-137 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
OOONCIOL_01163 2.4e-184 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OOONCIOL_01164 3.3e-39 yusU S Protein of unknown function (DUF2573)
OOONCIOL_01165 3.1e-150 yusV 3.6.3.34 HP ABC transporter
OOONCIOL_01166 7.2e-45 S YusW-like protein
OOONCIOL_01167 0.0 pepF2 E COG1164 Oligoendopeptidase F
OOONCIOL_01168 1.5e-147 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OOONCIOL_01169 4.7e-79 dps P Belongs to the Dps family
OOONCIOL_01170 3.8e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OOONCIOL_01171 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOONCIOL_01172 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
OOONCIOL_01173 3.4e-24
OOONCIOL_01174 2.9e-157 yuxN K Transcriptional regulator
OOONCIOL_01175 8.7e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OOONCIOL_01176 6.6e-24 S Protein of unknown function (DUF3970)
OOONCIOL_01177 4.6e-258 gerAA EG Spore germination protein
OOONCIOL_01178 3.6e-186 gerAB E Spore germination protein
OOONCIOL_01179 6e-205 gerAC S Spore germination B3/ GerAC like, C-terminal
OOONCIOL_01180 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OOONCIOL_01181 2.3e-193 vraS 2.7.13.3 T Histidine kinase
OOONCIOL_01182 2.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
OOONCIOL_01183 7.4e-126 liaG S Putative adhesin
OOONCIOL_01184 1.5e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
OOONCIOL_01185 8.1e-45 liaI S membrane
OOONCIOL_01186 1.8e-226 yvqJ EGP Major facilitator Superfamily
OOONCIOL_01187 7e-101 yvqK 2.5.1.17 S Adenosyltransferase
OOONCIOL_01188 1.8e-218 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
OOONCIOL_01189 5.8e-178 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOONCIOL_01190 7.2e-167 yvrC P ABC transporter substrate-binding protein
OOONCIOL_01191 4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OOONCIOL_01192 1.1e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
OOONCIOL_01193 0.0 T PhoQ Sensor
OOONCIOL_01194 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOONCIOL_01195 1.1e-36
OOONCIOL_01196 3.8e-102 yvrI K RNA polymerase
OOONCIOL_01197 1.6e-15 S YvrJ protein family
OOONCIOL_01198 7.8e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
OOONCIOL_01199 2.4e-66 yvrL S Regulatory protein YrvL
OOONCIOL_01200 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
OOONCIOL_01201 7.6e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOONCIOL_01202 1.9e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOONCIOL_01203 8.9e-178 fhuD P ABC transporter
OOONCIOL_01204 1.1e-127 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OOONCIOL_01205 7e-235 yvsH E Arginine ornithine antiporter
OOONCIOL_01206 5.2e-13 S Small spore protein J (Spore_SspJ)
OOONCIOL_01207 5.1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
OOONCIOL_01208 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OOONCIOL_01209 6.6e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
OOONCIOL_01210 2.6e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
OOONCIOL_01211 7.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
OOONCIOL_01212 8.6e-114 yfiK K Regulator
OOONCIOL_01213 4.3e-179 T Histidine kinase
OOONCIOL_01214 8.1e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
OOONCIOL_01215 1.3e-191 yfiM V ABC-2 type transporter
OOONCIOL_01216 7e-193 yfiN V COG0842 ABC-type multidrug transport system, permease component
OOONCIOL_01217 5e-156 yvgN S reductase
OOONCIOL_01218 2.7e-85 yvgO
OOONCIOL_01219 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
OOONCIOL_01220 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
OOONCIOL_01221 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OOONCIOL_01222 0.0 helD 3.6.4.12 L DNA helicase
OOONCIOL_01223 2.9e-97 yvgT S membrane
OOONCIOL_01224 1.7e-140 S Metallo-peptidase family M12
OOONCIOL_01225 6e-73 bdbC O Required for disulfide bond formation in some proteins
OOONCIOL_01226 3.8e-98 bdbD O Thioredoxin
OOONCIOL_01227 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OOONCIOL_01228 0.0 copA 3.6.3.54 P P-type ATPase
OOONCIOL_01229 2.6e-29 copZ P Heavy-metal-associated domain
OOONCIOL_01230 4.1e-47 csoR S transcriptional
OOONCIOL_01231 4.6e-191 yvaA 1.1.1.371 S Oxidoreductase
OOONCIOL_01232 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OOONCIOL_01233 8.4e-159 K Helix-turn-helix XRE-family like proteins
OOONCIOL_01234 2.2e-216 ynfM EGP Major Facilitator Superfamily
OOONCIOL_01235 2.4e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
OOONCIOL_01236 1.5e-141 S Amidohydrolase
OOONCIOL_01237 1.2e-252 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOONCIOL_01238 5.6e-46 ytnI O COG0695 Glutaredoxin and related proteins
OOONCIOL_01239 1.2e-180 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOONCIOL_01240 3.1e-139 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OOONCIOL_01241 7.1e-119 tcyM U Binding-protein-dependent transport system inner membrane component
OOONCIOL_01242 3.8e-120 tcyL P Binding-protein-dependent transport system inner membrane component
OOONCIOL_01243 7.8e-146 tcyK M Bacterial periplasmic substrate-binding proteins
OOONCIOL_01244 8.7e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
OOONCIOL_01245 3e-101 ytmI K Acetyltransferase (GNAT) domain
OOONCIOL_01246 2.5e-161 ytlI K LysR substrate binding domain
OOONCIOL_01247 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OOONCIOL_01248 2.3e-50 yrdF K ribonuclease inhibitor
OOONCIOL_01250 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OOONCIOL_01251 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OOONCIOL_01252 1.6e-142 est 3.1.1.1 S Carboxylesterase
OOONCIOL_01253 4.8e-24 secG U Preprotein translocase subunit SecG
OOONCIOL_01254 6e-35 yvzC K Transcriptional
OOONCIOL_01255 1e-69 K transcriptional
OOONCIOL_01256 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
OOONCIOL_01257 8.8e-53 yodB K transcriptional
OOONCIOL_01258 4.1e-259 T His Kinase A (phosphoacceptor) domain
OOONCIOL_01259 1.4e-121 K Transcriptional regulatory protein, C terminal
OOONCIOL_01260 1e-131 mutG S ABC-2 family transporter protein
OOONCIOL_01261 4.9e-123 spaE S ABC-2 family transporter protein
OOONCIOL_01262 7.9e-126 mutF V ABC transporter, ATP-binding protein
OOONCIOL_01263 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OOONCIOL_01264 3.3e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OOONCIOL_01265 1.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OOONCIOL_01266 3.3e-206 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OOONCIOL_01267 4.3e-76 yvbF K Belongs to the GbsR family
OOONCIOL_01268 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OOONCIOL_01269 5.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OOONCIOL_01270 2.9e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OOONCIOL_01271 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OOONCIOL_01272 7.1e-98 yvbF K Belongs to the GbsR family
OOONCIOL_01273 1.3e-103 yvbG U UPF0056 membrane protein
OOONCIOL_01274 1.7e-120 exoY M Membrane
OOONCIOL_01275 0.0 tcaA S response to antibiotic
OOONCIOL_01276 1.5e-80 yvbK 3.1.3.25 K acetyltransferase
OOONCIOL_01277 6.2e-211 EGP Major facilitator Superfamily
OOONCIOL_01278 3.3e-177
OOONCIOL_01279 7e-124 S GlcNAc-PI de-N-acetylase
OOONCIOL_01280 2.1e-142 C WbqC-like protein family
OOONCIOL_01281 4.6e-147 M Protein involved in cellulose biosynthesis
OOONCIOL_01282 4.5e-225 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OOONCIOL_01283 1.8e-170 5.1.3.2 M GDP-mannose 4,6 dehydratase
OOONCIOL_01284 2.6e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OOONCIOL_01285 8.9e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OOONCIOL_01286 2.2e-235 ywaD 3.4.11.10, 3.4.11.6 S PA domain
OOONCIOL_01287 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OOONCIOL_01288 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
OOONCIOL_01289 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OOONCIOL_01290 6.5e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OOONCIOL_01291 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OOONCIOL_01292 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OOONCIOL_01294 7.4e-253 araE EGP Major facilitator Superfamily
OOONCIOL_01295 1.4e-203 araR K transcriptional
OOONCIOL_01296 2.4e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOONCIOL_01298 5.3e-156 yvbU K Transcriptional regulator
OOONCIOL_01299 2.9e-157 yvbV EG EamA-like transporter family
OOONCIOL_01300 3.2e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
OOONCIOL_01302 4.2e-150 ybbH_1 K RpiR family transcriptional regulator
OOONCIOL_01303 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
OOONCIOL_01304 9.6e-210 gntP EG COG2610 H gluconate symporter and related permeases
OOONCIOL_01305 7.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OOONCIOL_01306 4e-270 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
OOONCIOL_01307 5.5e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OOONCIOL_01308 7.8e-219 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OOONCIOL_01309 6.6e-120 yvfI K COG2186 Transcriptional regulators
OOONCIOL_01310 3.8e-304 yvfH C L-lactate permease
OOONCIOL_01311 1.4e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
OOONCIOL_01312 2.7e-32 yvfG S YvfG protein
OOONCIOL_01313 3.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
OOONCIOL_01314 2e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OOONCIOL_01315 5.2e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
OOONCIOL_01316 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OOONCIOL_01317 5.3e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OOONCIOL_01318 6.8e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
OOONCIOL_01319 2.9e-204 epsI GM pyruvyl transferase
OOONCIOL_01320 4.9e-193 epsH GT2 S Glycosyltransferase like family 2
OOONCIOL_01321 7.7e-205 epsG S EpsG family
OOONCIOL_01322 6.1e-213 epsF GT4 M Glycosyl transferases group 1
OOONCIOL_01323 2e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OOONCIOL_01324 1.8e-217 epsD GT4 M Glycosyl transferase 4-like
OOONCIOL_01325 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
OOONCIOL_01326 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
OOONCIOL_01327 4.6e-118 ywqC M biosynthesis protein
OOONCIOL_01328 4.3e-77 slr K transcriptional
OOONCIOL_01329 2.7e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
OOONCIOL_01330 3.7e-96 ywjB H RibD C-terminal domain
OOONCIOL_01331 1.5e-112 yyaS S Membrane
OOONCIOL_01332 3.5e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OOONCIOL_01333 2.1e-93 padC Q Phenolic acid decarboxylase
OOONCIOL_01334 7.7e-16 S Protein of unknown function (DUF1433)
OOONCIOL_01335 2.2e-17 S Protein of unknown function (DUF1433)
OOONCIOL_01336 9.8e-18 S Protein of unknown function (DUF1433)
OOONCIOL_01337 3.2e-267 I Pfam Lipase (class 3)
OOONCIOL_01338 2.6e-33
OOONCIOL_01340 1e-292 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
OOONCIOL_01341 1.8e-218 rafB P LacY proton/sugar symporter
OOONCIOL_01342 1.1e-181 scrR K transcriptional
OOONCIOL_01343 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OOONCIOL_01344 3.3e-163 yraN K Transcriptional regulator
OOONCIOL_01345 1.4e-209 yraM S PrpF protein
OOONCIOL_01346 4.6e-247 EGP Sugar (and other) transporter
OOONCIOL_01347 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
OOONCIOL_01348 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
OOONCIOL_01349 7.3e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
OOONCIOL_01350 2.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OOONCIOL_01351 6.2e-182 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OOONCIOL_01352 8.2e-79 M Ribonuclease
OOONCIOL_01353 3.7e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
OOONCIOL_01354 4.7e-36 crh G Phosphocarrier protein Chr
OOONCIOL_01355 5.3e-170 whiA K May be required for sporulation
OOONCIOL_01356 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OOONCIOL_01357 1.1e-166 rapZ S Displays ATPase and GTPase activities
OOONCIOL_01358 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OOONCIOL_01359 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OOONCIOL_01360 1.3e-124 usp CBM50 M protein conserved in bacteria
OOONCIOL_01361 2.5e-275 S COG0457 FOG TPR repeat
OOONCIOL_01362 4.4e-189 sasA T Histidine kinase
OOONCIOL_01363 1.2e-120 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOONCIOL_01364 2.6e-46
OOONCIOL_01365 0.0 msbA2 3.6.3.44 V ABC transporter
OOONCIOL_01366 6.9e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
OOONCIOL_01367 1.7e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
OOONCIOL_01368 1.3e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OOONCIOL_01369 1.6e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OOONCIOL_01370 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
OOONCIOL_01371 1.4e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OOONCIOL_01372 5.6e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
OOONCIOL_01373 2.3e-207 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OOONCIOL_01374 3.5e-137 yvpB NU protein conserved in bacteria
OOONCIOL_01375 1.3e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
OOONCIOL_01376 5.9e-112 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
OOONCIOL_01377 3.1e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OOONCIOL_01378 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OOONCIOL_01379 8.9e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OOONCIOL_01380 1.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OOONCIOL_01381 2.3e-133 yvoA K transcriptional
OOONCIOL_01382 4.4e-103 yxaF K Transcriptional regulator
OOONCIOL_01383 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
OOONCIOL_01384 1.5e-40 yvlD S Membrane
OOONCIOL_01385 9.6e-26 pspB KT PspC domain
OOONCIOL_01386 6e-165 yvlB S Putative adhesin
OOONCIOL_01387 6.1e-49 yvlA
OOONCIOL_01388 2.2e-32 yvkN
OOONCIOL_01389 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OOONCIOL_01390 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OOONCIOL_01391 7.6e-33 csbA S protein conserved in bacteria
OOONCIOL_01392 0.0 yvkC 2.7.9.2 GT Phosphotransferase
OOONCIOL_01393 5.9e-109 yvkB K Transcriptional regulator
OOONCIOL_01394 1.3e-225 yvkA EGP Major facilitator Superfamily
OOONCIOL_01395 2.2e-08 L Transposase, Mutator family
OOONCIOL_01396 2.3e-52 L For insertion sequence element IS256 in transposon Tn4001
OOONCIOL_01397 1.3e-26 bacT Q Thioesterase domain
OOONCIOL_01399 1.3e-177 S Psort location CytoplasmicMembrane, score
OOONCIOL_01400 8.3e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OOONCIOL_01401 1.5e-55 swrA S Swarming motility protein
OOONCIOL_01402 2.4e-251 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
OOONCIOL_01403 8.6e-225 ywoF P Right handed beta helix region
OOONCIOL_01404 1.2e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
OOONCIOL_01405 2.3e-122 ftsE D cell division ATP-binding protein FtsE
OOONCIOL_01406 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
OOONCIOL_01407 8.7e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
OOONCIOL_01408 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OOONCIOL_01409 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OOONCIOL_01410 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OOONCIOL_01411 6.8e-68
OOONCIOL_01412 4.5e-10 fliT S bacterial-type flagellum organization
OOONCIOL_01413 3e-66 fliS N flagellar protein FliS
OOONCIOL_01414 4e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OOONCIOL_01415 7.1e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OOONCIOL_01416 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OOONCIOL_01417 7.2e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OOONCIOL_01418 1.5e-79 yviE
OOONCIOL_01419 2.3e-162 flgL N Belongs to the bacterial flagellin family
OOONCIOL_01420 1.2e-272 flgK N flagellar hook-associated protein
OOONCIOL_01421 8.9e-81 flgN NOU FlgN protein
OOONCIOL_01422 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
OOONCIOL_01423 4.1e-74 yvyF S flagellar protein
OOONCIOL_01424 2.5e-75 comFC S Phosphoribosyl transferase domain
OOONCIOL_01425 1.7e-42 comFB S Late competence development protein ComFB
OOONCIOL_01426 2.1e-255 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OOONCIOL_01427 3.2e-158 degV S protein conserved in bacteria
OOONCIOL_01428 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OOONCIOL_01429 3.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
OOONCIOL_01430 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
OOONCIOL_01431 1e-165 yvhJ K Transcriptional regulator
OOONCIOL_01432 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
OOONCIOL_01433 1.1e-233 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
OOONCIOL_01434 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
OOONCIOL_01435 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
OOONCIOL_01436 8.9e-254 tuaE M Teichuronic acid biosynthesis protein
OOONCIOL_01437 4.2e-245 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OOONCIOL_01438 6.8e-223 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
OOONCIOL_01439 6.1e-258 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OOONCIOL_01440 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OOONCIOL_01441 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOONCIOL_01442 0.0 lytB 3.5.1.28 D Stage II sporulation protein
OOONCIOL_01443 6.6e-48
OOONCIOL_01444 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OOONCIOL_01445 2e-208 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OOONCIOL_01446 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OOONCIOL_01447 1.1e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OOONCIOL_01448 1.7e-151 tagG GM Transport permease protein
OOONCIOL_01449 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OOONCIOL_01450 7.8e-280 M Glycosyltransferase like family 2
OOONCIOL_01451 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
OOONCIOL_01452 1.4e-141 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OOONCIOL_01453 1.6e-216 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OOONCIOL_01454 2.3e-239 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OOONCIOL_01455 8.5e-184 pmi 5.3.1.8 G mannose-6-phosphate isomerase
OOONCIOL_01456 6.3e-263 gerBA EG Spore germination protein
OOONCIOL_01457 7.8e-197 gerBB E Spore germination protein
OOONCIOL_01458 1.8e-209 gerAC S Spore germination protein
OOONCIOL_01459 1.5e-266 GT2,GT4 J Glycosyl transferase family 2
OOONCIOL_01460 4.9e-249 ywtG EGP Major facilitator Superfamily
OOONCIOL_01461 7.2e-178 ywtF K Transcriptional regulator
OOONCIOL_01462 5.2e-156 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
OOONCIOL_01463 5e-35 yttA 2.7.13.3 S Pfam Transposase IS66
OOONCIOL_01464 7.3e-236 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OOONCIOL_01465 1.3e-20 ywtC
OOONCIOL_01466 2.8e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
OOONCIOL_01467 2.3e-70 pgsC S biosynthesis protein
OOONCIOL_01468 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
OOONCIOL_01469 7.7e-184 gerKA EG Spore germination protein
OOONCIOL_01470 3.1e-190 gerKB E Spore germination protein
OOONCIOL_01471 1.5e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
OOONCIOL_01472 3.2e-178 rbsR K transcriptional
OOONCIOL_01473 1.2e-155 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OOONCIOL_01474 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
OOONCIOL_01475 7.1e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
OOONCIOL_01476 6.5e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
OOONCIOL_01477 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
OOONCIOL_01478 3.4e-89 batE T Sh3 type 3 domain protein
OOONCIOL_01479 5.3e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
OOONCIOL_01480 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
OOONCIOL_01481 6.8e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OOONCIOL_01482 2.6e-166 alsR K LysR substrate binding domain
OOONCIOL_01484 2.7e-236 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OOONCIOL_01485 7.5e-126 ywrJ
OOONCIOL_01486 2.8e-128 cotB
OOONCIOL_01487 5e-212 cotH M Spore Coat
OOONCIOL_01488 2e-09
OOONCIOL_01489 2.8e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OOONCIOL_01491 1.7e-298 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OOONCIOL_01492 6.1e-82 ywrC K Transcriptional regulator
OOONCIOL_01493 9.5e-101 ywrB P Chromate transporter
OOONCIOL_01494 1.9e-87 ywrA P COG2059 Chromate transport protein ChrA
OOONCIOL_01496 9.7e-92 ywqN S NAD(P)H-dependent
OOONCIOL_01497 3.1e-156 K Transcriptional regulator
OOONCIOL_01498 6.7e-133 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
OOONCIOL_01499 2.3e-61
OOONCIOL_01500 1.7e-13
OOONCIOL_01502 3.4e-306 ywqJ S Pre-toxin TG
OOONCIOL_01503 4.3e-37 ywqI S Family of unknown function (DUF5344)
OOONCIOL_01504 1.4e-21 S Domain of unknown function (DUF5082)
OOONCIOL_01505 5.3e-147 ywqG S Domain of unknown function (DUF1963)
OOONCIOL_01506 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OOONCIOL_01507 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
OOONCIOL_01508 9.6e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
OOONCIOL_01509 8.3e-110 ywqC M biosynthesis protein
OOONCIOL_01510 1.3e-14
OOONCIOL_01511 1.6e-307 ywqB S SWIM zinc finger
OOONCIOL_01512 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OOONCIOL_01513 2.4e-153 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
OOONCIOL_01514 7.5e-138 glcR K DeoR C terminal sensor domain
OOONCIOL_01515 3.7e-57 ssbB L Single-stranded DNA-binding protein
OOONCIOL_01516 4e-62 ywpG
OOONCIOL_01517 2.5e-68 ywpF S YwpF-like protein
OOONCIOL_01518 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OOONCIOL_01519 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OOONCIOL_01520 5.2e-198 S aspartate phosphatase
OOONCIOL_01521 7e-142 flhP N flagellar basal body
OOONCIOL_01522 3.2e-128 flhO N flagellar basal body
OOONCIOL_01523 2.7e-180 mbl D Rod shape-determining protein
OOONCIOL_01524 1.8e-44 spoIIID K Stage III sporulation protein D
OOONCIOL_01525 2.5e-71 ywoH K transcriptional
OOONCIOL_01526 4.1e-212 ywoG EGP Major facilitator Superfamily
OOONCIOL_01527 3.9e-273 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
OOONCIOL_01528 1.6e-244 ywoD EGP Major facilitator superfamily
OOONCIOL_01529 2.8e-102 phzA Q Isochorismatase family
OOONCIOL_01530 2.5e-228 amt P Ammonium transporter
OOONCIOL_01531 2e-58 nrgB K Belongs to the P(II) protein family
OOONCIOL_01532 3.9e-207 ftsW D Belongs to the SEDS family
OOONCIOL_01533 5.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
OOONCIOL_01534 8.1e-70 ywnJ S VanZ like family
OOONCIOL_01535 1.3e-119 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
OOONCIOL_01536 4.9e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
OOONCIOL_01537 1.2e-10 ywnC S Family of unknown function (DUF5362)
OOONCIOL_01538 4.2e-69 ywnF S Family of unknown function (DUF5392)
OOONCIOL_01539 5.5e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OOONCIOL_01540 1.2e-51 ywnC S Family of unknown function (DUF5362)
OOONCIOL_01541 2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
OOONCIOL_01542 6.1e-67 ywnA K Transcriptional regulator
OOONCIOL_01543 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
OOONCIOL_01544 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
OOONCIOL_01545 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
OOONCIOL_01546 1.4e-10 csbD K CsbD-like
OOONCIOL_01547 2.3e-81 ywmF S Peptidase M50
OOONCIOL_01548 2.8e-93 S response regulator aspartate phosphatase
OOONCIOL_01549 1.6e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OOONCIOL_01550 2.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OOONCIOL_01552 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
OOONCIOL_01553 5.1e-114 ywmC S protein containing a von Willebrand factor type A (vWA) domain
OOONCIOL_01554 4e-179 spoIID D Stage II sporulation protein D
OOONCIOL_01555 1.1e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OOONCIOL_01556 2.2e-134 ywmB S TATA-box binding
OOONCIOL_01557 4.8e-32 ywzB S membrane
OOONCIOL_01558 8.7e-89 ywmA
OOONCIOL_01559 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OOONCIOL_01560 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OOONCIOL_01561 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OOONCIOL_01562 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OOONCIOL_01563 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OOONCIOL_01564 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OOONCIOL_01565 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OOONCIOL_01566 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
OOONCIOL_01567 2.1e-61 atpI S ATP synthase
OOONCIOL_01568 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OOONCIOL_01569 5.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OOONCIOL_01570 1.7e-96 ywlG S Belongs to the UPF0340 family
OOONCIOL_01571 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
OOONCIOL_01572 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OOONCIOL_01573 1.3e-83 mntP P Probably functions as a manganese efflux pump
OOONCIOL_01574 1.5e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OOONCIOL_01575 3.9e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
OOONCIOL_01576 8.9e-119 spoIIR S stage II sporulation protein R
OOONCIOL_01577 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
OOONCIOL_01579 2.4e-153 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OOONCIOL_01580 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OOONCIOL_01581 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OOONCIOL_01582 2.8e-94 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
OOONCIOL_01583 6.8e-157 ywkB S Membrane transport protein
OOONCIOL_01584 0.0 sfcA 1.1.1.38 C malic enzyme
OOONCIOL_01585 1.7e-102 tdk 2.7.1.21 F thymidine kinase
OOONCIOL_01586 1.1e-32 rpmE J Binds the 23S rRNA
OOONCIOL_01587 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OOONCIOL_01588 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
OOONCIOL_01589 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OOONCIOL_01590 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OOONCIOL_01591 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
OOONCIOL_01592 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
OOONCIOL_01593 4.2e-92 ywjG S Domain of unknown function (DUF2529)
OOONCIOL_01594 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OOONCIOL_01595 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OOONCIOL_01596 0.0 fadF C COG0247 Fe-S oxidoreductase
OOONCIOL_01597 2.3e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
OOONCIOL_01598 1.8e-178 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
OOONCIOL_01599 4.2e-43 ywjC
OOONCIOL_01600 0.0 ywjA V ABC transporter
OOONCIOL_01601 1e-295 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OOONCIOL_01602 3.4e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OOONCIOL_01603 7.2e-121 narI 1.7.5.1 C nitrate reductase, gamma
OOONCIOL_01604 1.4e-93 narJ 1.7.5.1 C nitrate reductase
OOONCIOL_01605 2.8e-295 narH 1.7.5.1 C Nitrate reductase, beta
OOONCIOL_01606 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OOONCIOL_01607 1.3e-84 arfM T cyclic nucleotide binding
OOONCIOL_01608 1.8e-138 ywiC S YwiC-like protein
OOONCIOL_01609 3.2e-127 fnr K helix_turn_helix, cAMP Regulatory protein
OOONCIOL_01610 2.4e-212 narK P COG2223 Nitrate nitrite transporter
OOONCIOL_01611 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OOONCIOL_01612 1e-43 ywiB S protein conserved in bacteria
OOONCIOL_01613 8.1e-72 S aspartate phosphatase
OOONCIOL_01615 9.7e-29 ydcG K sequence-specific DNA binding
OOONCIOL_01616 3.6e-31
OOONCIOL_01618 2.6e-75 CP Membrane
OOONCIOL_01621 7.8e-168 speB 3.5.3.11 E Belongs to the arginase family
OOONCIOL_01622 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OOONCIOL_01623 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OOONCIOL_01624 1.6e-81
OOONCIOL_01625 2.9e-93 ywhD S YwhD family
OOONCIOL_01626 4.7e-117 ywhC S Peptidase family M50
OOONCIOL_01627 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
OOONCIOL_01628 4.9e-67 ywhA K Transcriptional regulator
OOONCIOL_01629 1.9e-245 yhdG_1 E C-terminus of AA_permease
OOONCIOL_01630 4.6e-88 ywgA 2.1.1.72, 3.1.21.3
OOONCIOL_01631 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
OOONCIOL_01632 6.9e-36 ywzC S Belongs to the UPF0741 family
OOONCIOL_01633 6.6e-110 rsfA_1
OOONCIOL_01634 9.7e-52 padR K PadR family transcriptional regulator
OOONCIOL_01635 1.1e-93 S membrane
OOONCIOL_01636 1.4e-162 V ABC transporter, ATP-binding protein
OOONCIOL_01637 7.2e-167 yhcI S ABC transporter (permease)
OOONCIOL_01640 7e-175
OOONCIOL_01642 1.5e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
OOONCIOL_01643 6e-163 cysL K Transcriptional regulator
OOONCIOL_01644 8.2e-158 MA20_14895 S Conserved hypothetical protein 698
OOONCIOL_01645 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
OOONCIOL_01646 1.1e-146 ywfI C May function as heme-dependent peroxidase
OOONCIOL_01647 5.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
OOONCIOL_01648 1.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
OOONCIOL_01649 1.4e-207 bacE EGP Major facilitator Superfamily
OOONCIOL_01650 8.3e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
OOONCIOL_01651 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOONCIOL_01652 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
OOONCIOL_01653 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
OOONCIOL_01654 3.5e-222 ywfA EGP Major facilitator Superfamily
OOONCIOL_01655 4.9e-205 tcaB EGP Major facilitator Superfamily
OOONCIOL_01656 1.2e-258 lysP E amino acid
OOONCIOL_01657 0.0 rocB E arginine degradation protein
OOONCIOL_01658 8.6e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OOONCIOL_01659 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OOONCIOL_01660 4.1e-59
OOONCIOL_01661 3e-86 spsL 5.1.3.13 M Spore Coat
OOONCIOL_01662 4e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OOONCIOL_01663 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OOONCIOL_01664 1.2e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OOONCIOL_01665 2.8e-177 spsG M Spore Coat
OOONCIOL_01666 2.6e-132 spsF M Spore Coat
OOONCIOL_01667 3.8e-215 spsE 2.5.1.56 M acid synthase
OOONCIOL_01668 2e-155 spsD 2.3.1.210 K Spore Coat
OOONCIOL_01669 4.5e-219 spsC E Belongs to the DegT DnrJ EryC1 family
OOONCIOL_01670 1.7e-273 spsB M Capsule polysaccharide biosynthesis protein
OOONCIOL_01671 1.3e-142 spsA M Spore Coat
OOONCIOL_01672 4e-61 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
OOONCIOL_01673 4.2e-46 ywdK S small membrane protein
OOONCIOL_01674 5.4e-229 ywdJ F Xanthine uracil
OOONCIOL_01675 4.7e-41 ywdI S Family of unknown function (DUF5327)
OOONCIOL_01676 2.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OOONCIOL_01677 9.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
OOONCIOL_01679 5.8e-88 ywdD
OOONCIOL_01680 6.3e-57 pex K Transcriptional regulator PadR-like family
OOONCIOL_01681 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OOONCIOL_01682 7.4e-20 ywdA
OOONCIOL_01683 8.3e-284 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
OOONCIOL_01684 3.4e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OOONCIOL_01685 2.8e-151 sacT K transcriptional antiterminator
OOONCIOL_01687 0.0 vpr O Belongs to the peptidase S8 family
OOONCIOL_01688 3.6e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOONCIOL_01689 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
OOONCIOL_01690 1e-207 rodA D Belongs to the SEDS family
OOONCIOL_01691 1.7e-76 ysnE K acetyltransferase
OOONCIOL_01692 2.3e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
OOONCIOL_01693 2.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OOONCIOL_01694 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OOONCIOL_01695 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OOONCIOL_01696 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
OOONCIOL_01697 8.4e-27 ywzA S membrane
OOONCIOL_01698 9.5e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OOONCIOL_01699 5.1e-61 gtcA S GtrA-like protein
OOONCIOL_01700 1.3e-111 ywcC K Bacterial regulatory proteins, tetR family
OOONCIOL_01702 7.3e-129 H Methionine biosynthesis protein MetW
OOONCIOL_01703 1.6e-131 S Streptomycin biosynthesis protein StrF
OOONCIOL_01704 3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OOONCIOL_01705 2.2e-240 ywbN P Dyp-type peroxidase family protein
OOONCIOL_01706 1.9e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
OOONCIOL_01707 4.8e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OOONCIOL_01708 8.2e-152 ywbI K Transcriptional regulator
OOONCIOL_01709 4.2e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
OOONCIOL_01710 1.3e-109 ywbG M effector of murein hydrolase
OOONCIOL_01711 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
OOONCIOL_01712 4.8e-137 mta K transcriptional
OOONCIOL_01713 8.8e-223 ywbD 2.1.1.191 J Methyltransferase
OOONCIOL_01714 7.6e-67 ywbC 4.4.1.5 E glyoxalase
OOONCIOL_01715 7.1e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OOONCIOL_01716 1.7e-262 epr 3.4.21.62 O Belongs to the peptidase S8 family
OOONCIOL_01717 4.1e-161 gspA M General stress
OOONCIOL_01718 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
OOONCIOL_01719 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
OOONCIOL_01720 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
OOONCIOL_01721 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOONCIOL_01722 4.8e-229 dltB M membrane protein involved in D-alanine export
OOONCIOL_01723 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOONCIOL_01724 1.2e-227 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OOONCIOL_01725 1.9e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OOONCIOL_01726 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OOONCIOL_01727 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
OOONCIOL_01728 8.2e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OOONCIOL_01729 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
OOONCIOL_01730 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
OOONCIOL_01731 3.5e-111 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
OOONCIOL_01732 2.8e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOONCIOL_01733 7.9e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOONCIOL_01734 1.5e-166 cbrA3 P Periplasmic binding protein
OOONCIOL_01735 1.7e-57 arsR K transcriptional
OOONCIOL_01736 6.5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OOONCIOL_01737 5.8e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
OOONCIOL_01738 2.3e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
OOONCIOL_01739 3.5e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OOONCIOL_01740 2.8e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OOONCIOL_01741 1.1e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
OOONCIOL_01742 1.8e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
OOONCIOL_01743 2.1e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
OOONCIOL_01744 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OOONCIOL_01745 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
OOONCIOL_01746 7.9e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
OOONCIOL_01747 4.2e-155 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OOONCIOL_01748 3.8e-291 cydD V ATP-binding protein
OOONCIOL_01749 0.0 cydD V ATP-binding
OOONCIOL_01750 2.5e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
OOONCIOL_01751 4.5e-266 cydA 1.10.3.14 C oxidase, subunit
OOONCIOL_01752 1e-214 cimH C COG3493 Na citrate symporter
OOONCIOL_01753 4.3e-155 yxkH G Polysaccharide deacetylase
OOONCIOL_01754 2.6e-205 msmK P Belongs to the ABC transporter superfamily
OOONCIOL_01755 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
OOONCIOL_01756 3.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OOONCIOL_01757 3.8e-87 yxkC S Domain of unknown function (DUF4352)
OOONCIOL_01758 8.2e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OOONCIOL_01759 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OOONCIOL_01762 9.1e-86 yxjI S LURP-one-related
OOONCIOL_01763 1.2e-216 yxjG 2.1.1.14 E Methionine synthase
OOONCIOL_01764 6.5e-154 rlmA 2.1.1.187 Q Methyltransferase domain
OOONCIOL_01765 2.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OOONCIOL_01766 1.8e-71 T Domain of unknown function (DUF4163)
OOONCIOL_01767 1.5e-49 yxiS
OOONCIOL_01768 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
OOONCIOL_01769 1.4e-221 citH C Citrate transporter
OOONCIOL_01770 2e-140 exoK GH16 M licheninase activity
OOONCIOL_01772 2.2e-104 licT K transcriptional antiterminator
OOONCIOL_01773 7.9e-222 yxiO S COG2270 Permeases of the major facilitator superfamily
OOONCIOL_01774 3.4e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
OOONCIOL_01776 1.9e-21
OOONCIOL_01777 1.5e-14 S YxiJ-like protein
OOONCIOL_01778 2.1e-109
OOONCIOL_01779 5.6e-77
OOONCIOL_01780 8.6e-69 yxiG
OOONCIOL_01781 5.7e-60 yxxG
OOONCIOL_01783 6.5e-19
OOONCIOL_01785 3e-39 S Protein of unknown function (DUF2750)
OOONCIOL_01786 0.0 wapA M COG3209 Rhs family protein
OOONCIOL_01787 1.2e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
OOONCIOL_01788 3.6e-147 yxxF EG EamA-like transporter family
OOONCIOL_01789 1.8e-72 yxiE T Belongs to the universal stress protein A family
OOONCIOL_01790 0.0 L HKD family nuclease
OOONCIOL_01791 5.5e-65 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OOONCIOL_01792 1.5e-274 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OOONCIOL_01793 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
OOONCIOL_01794 1.1e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
OOONCIOL_01795 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OOONCIOL_01796 1.4e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
OOONCIOL_01797 7.2e-175 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
OOONCIOL_01798 4.4e-253 lysP E amino acid
OOONCIOL_01799 7.4e-231 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
OOONCIOL_01800 6.8e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OOONCIOL_01801 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OOONCIOL_01802 9.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OOONCIOL_01803 2.6e-149 yidA S hydrolases of the HAD superfamily
OOONCIOL_01807 8.4e-23 yxeD
OOONCIOL_01808 1.3e-34
OOONCIOL_01809 4.1e-178 fhuD P Periplasmic binding protein
OOONCIOL_01810 1.3e-57 yxeA S Protein of unknown function (DUF1093)
OOONCIOL_01811 0.0 yxdM V ABC transporter (permease)
OOONCIOL_01812 3.6e-140 yxdL V ABC transporter, ATP-binding protein
OOONCIOL_01813 2.5e-175 T PhoQ Sensor
OOONCIOL_01814 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOONCIOL_01815 1.1e-156 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
OOONCIOL_01816 1.9e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
OOONCIOL_01817 3.3e-166 iolH G Xylose isomerase-like TIM barrel
OOONCIOL_01818 2e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
OOONCIOL_01819 6.7e-232 iolF EGP Major facilitator Superfamily
OOONCIOL_01820 3.4e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
OOONCIOL_01821 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
OOONCIOL_01822 2.7e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
OOONCIOL_01823 1.6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
OOONCIOL_01824 1.8e-278 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OOONCIOL_01825 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
OOONCIOL_01826 1.2e-174 iolS C Aldo keto reductase
OOONCIOL_01827 4.3e-245 csbC EGP Major facilitator Superfamily
OOONCIOL_01828 0.0 htpG O Molecular chaperone. Has ATPase activity
OOONCIOL_01830 1.8e-150 IQ Enoyl-(Acyl carrier protein) reductase
OOONCIOL_01831 2.3e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OOONCIOL_01832 4.5e-200 desK 2.7.13.3 T Histidine kinase
OOONCIOL_01833 1.8e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
OOONCIOL_01834 4.7e-213 yxbF K Bacterial regulatory proteins, tetR family
OOONCIOL_01835 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OOONCIOL_01836 1.4e-141 S PQQ-like domain
OOONCIOL_01837 1.7e-64 S Family of unknown function (DUF5391)
OOONCIOL_01838 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
OOONCIOL_01839 1.9e-201 EGP Major facilitator Superfamily
OOONCIOL_01840 3.8e-73 yxaI S membrane protein domain
OOONCIOL_01841 7.9e-123 E Ring-cleavage extradiol dioxygenase
OOONCIOL_01842 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
OOONCIOL_01843 2.3e-287 ahpF O Alkyl hydroperoxide reductase
OOONCIOL_01844 5.5e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
OOONCIOL_01845 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
OOONCIOL_01846 4.6e-82 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
OOONCIOL_01847 3.6e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
OOONCIOL_01848 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
OOONCIOL_01849 2.2e-87 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
OOONCIOL_01850 2.8e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OOONCIOL_01851 3.7e-177 S Fusaric acid resistance protein-like
OOONCIOL_01852 7.2e-18
OOONCIOL_01853 1.7e-190 S KAP family P-loop domain
OOONCIOL_01854 1e-39
OOONCIOL_01855 2.5e-124 S Protein of unknown function DUF262
OOONCIOL_01856 1.7e-79 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OOONCIOL_01857 7.9e-08 S YyzF-like protein
OOONCIOL_01859 3.3e-214 yycP
OOONCIOL_01860 4.5e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OOONCIOL_01861 5.1e-184 C oxidoreductases (related to aryl-alcohol dehydrogenases)
OOONCIOL_01862 1.4e-86 yycN 2.3.1.128 K Acetyltransferase
OOONCIOL_01864 6.4e-199 S Histidine kinase
OOONCIOL_01865 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
OOONCIOL_01866 3.8e-257 rocE E amino acid
OOONCIOL_01867 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
OOONCIOL_01868 7.7e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OOONCIOL_01869 1.7e-144 1.14.11.27 P peptidyl-arginine hydroxylation
OOONCIOL_01870 1.3e-304 S ABC transporter
OOONCIOL_01871 9.9e-198 S Major Facilitator Superfamily
OOONCIOL_01872 4.7e-257
OOONCIOL_01873 1e-187 2.7.7.73, 2.7.7.80 H ThiF family
OOONCIOL_01874 3.1e-246 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
OOONCIOL_01875 4.7e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOONCIOL_01876 1.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OOONCIOL_01877 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
OOONCIOL_01878 1.4e-150 yycI S protein conserved in bacteria
OOONCIOL_01879 2.5e-261 yycH S protein conserved in bacteria
OOONCIOL_01880 0.0 vicK 2.7.13.3 T Histidine kinase
OOONCIOL_01881 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOONCIOL_01886 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OOONCIOL_01887 8.5e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OOONCIOL_01888 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OOONCIOL_01889 5.7e-26 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
OOONCIOL_01891 4.6e-17 yycC K YycC-like protein
OOONCIOL_01892 1.4e-234 M Glycosyltransferase Family 4
OOONCIOL_01893 2.6e-202 S Ecdysteroid kinase
OOONCIOL_01894 2.5e-233 S Carbamoyl-phosphate synthase L chain, ATP binding domain
OOONCIOL_01895 3.9e-243 M Glycosyltransferase Family 4
OOONCIOL_01896 2.7e-120 S GlcNAc-PI de-N-acetylase
OOONCIOL_01897 8.2e-102 KLT COG0515 Serine threonine protein kinase
OOONCIOL_01898 4.9e-73 rplI J binds to the 23S rRNA
OOONCIOL_01899 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OOONCIOL_01900 1.2e-158 yybS S membrane
OOONCIOL_01902 2.1e-83 cotF M Spore coat protein
OOONCIOL_01903 8.2e-66 ydeP3 K Transcriptional regulator
OOONCIOL_01904 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
OOONCIOL_01905 1.4e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OOONCIOL_01906 2.9e-273 sacB 2.4.1.10 GH68 M levansucrase activity
OOONCIOL_01907 2.1e-311 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
OOONCIOL_01908 2.2e-114 K FCD domain
OOONCIOL_01909 3.6e-64 dinB S PFAM DinB family protein
OOONCIOL_01910 4.6e-158 G Major Facilitator Superfamily
OOONCIOL_01911 2.2e-55 ypaA S Protein of unknown function (DUF1304)
OOONCIOL_01912 5.6e-115 drgA C nitroreductase
OOONCIOL_01913 4.1e-69 ydgJ K Winged helix DNA-binding domain
OOONCIOL_01914 1.5e-150 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OOONCIOL_01915 1.6e-76 yybA 2.3.1.57 K transcriptional
OOONCIOL_01916 3.2e-161 eaeH M Domain of Unknown Function (DUF1259)
OOONCIOL_01917 5.2e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
OOONCIOL_01918 8.6e-162 K Transcriptional regulator
OOONCIOL_01919 6.6e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
OOONCIOL_01920 1.6e-250 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OOONCIOL_01921 1.8e-130 ydfC EG EamA-like transporter family
OOONCIOL_01922 4.3e-99 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OOONCIOL_01923 3.3e-78 K Transcriptional regulator
OOONCIOL_01924 2.1e-40 qacC U Small Multidrug Resistance protein
OOONCIOL_01925 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
OOONCIOL_01926 1.9e-161 yyaK S CAAX protease self-immunity
OOONCIOL_01927 2e-247 ydjK G Sugar (and other) transporter
OOONCIOL_01928 9.9e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OOONCIOL_01929 5.2e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
OOONCIOL_01930 7.8e-140 xth 3.1.11.2 L exodeoxyribonuclease III
OOONCIOL_01931 2.7e-97 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OOONCIOL_01932 6.3e-105 adaA 3.2.2.21 K Transcriptional regulator
OOONCIOL_01933 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OOONCIOL_01934 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OOONCIOL_01935 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
OOONCIOL_01936 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OOONCIOL_01937 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OOONCIOL_01938 2.3e-33 yyzM S protein conserved in bacteria
OOONCIOL_01939 5.3e-176 yyaD S Membrane
OOONCIOL_01940 6.2e-111 yyaC S Sporulation protein YyaC
OOONCIOL_01941 3e-148 spo0J K Belongs to the ParB family
OOONCIOL_01942 2.6e-135 soj D COG1192 ATPases involved in chromosome partitioning
OOONCIOL_01943 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
OOONCIOL_01944 7.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
OOONCIOL_01945 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OOONCIOL_01946 1.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OOONCIOL_01947 8.7e-108 jag S single-stranded nucleic acid binding R3H
OOONCIOL_01948 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OOONCIOL_01949 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
OOONCIOL_01950 2.3e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OOONCIOL_01951 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OOONCIOL_01952 2.4e-33 yaaA S S4 domain
OOONCIOL_01953 1.6e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OOONCIOL_01954 8.1e-38 yaaB S Domain of unknown function (DUF370)
OOONCIOL_01955 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OOONCIOL_01956 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OOONCIOL_01959 2.2e-182 yaaC S YaaC-like Protein
OOONCIOL_01960 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
OOONCIOL_01961 2.3e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OOONCIOL_01962 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OOONCIOL_01963 2.8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OOONCIOL_01964 1.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OOONCIOL_01965 3.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OOONCIOL_01966 1.3e-09
OOONCIOL_01967 1e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
OOONCIOL_01968 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
OOONCIOL_01969 3.8e-211 yaaH M Glycoside Hydrolase Family
OOONCIOL_01970 1.1e-98 yaaI Q COG1335 Amidases related to nicotinamidase
OOONCIOL_01971 1.7e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OOONCIOL_01972 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OOONCIOL_01973 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OOONCIOL_01974 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OOONCIOL_01975 3.6e-32 yaaL S Protein of unknown function (DUF2508)
OOONCIOL_01976 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
OOONCIOL_01977 3.4e-39 S COG NOG14552 non supervised orthologous group
OOONCIOL_01980 3.2e-21 S ORF located using Blastx
OOONCIOL_01981 1.7e-51 S COG NOG14600 non supervised orthologous group
OOONCIOL_01982 3.8e-30 csfB S Inhibitor of sigma-G Gin
OOONCIOL_01983 3.3e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
OOONCIOL_01984 2.7e-189 yaaN P Belongs to the TelA family
OOONCIOL_01985 1.2e-266 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
OOONCIOL_01986 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OOONCIOL_01987 7.5e-55 yaaQ S protein conserved in bacteria
OOONCIOL_01988 1.2e-71 yaaR S protein conserved in bacteria
OOONCIOL_01989 1.3e-182 holB 2.7.7.7 L DNA polymerase III
OOONCIOL_01990 8.8e-145 yaaT S stage 0 sporulation protein
OOONCIOL_01991 7.7e-37 yabA L Involved in initiation control of chromosome replication
OOONCIOL_01992 4.4e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
OOONCIOL_01993 5.2e-47 yazA L endonuclease containing a URI domain
OOONCIOL_01994 1.4e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OOONCIOL_01995 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
OOONCIOL_01996 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OOONCIOL_01997 5.9e-143 tatD L hydrolase, TatD
OOONCIOL_01998 2.7e-231 rpfB GH23 T protein conserved in bacteria
OOONCIOL_01999 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OOONCIOL_02000 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OOONCIOL_02001 8.4e-146 yabG S peptidase
OOONCIOL_02002 7.8e-39 veg S protein conserved in bacteria
OOONCIOL_02003 2.9e-27 sspF S DNA topological change
OOONCIOL_02004 3.5e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OOONCIOL_02005 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OOONCIOL_02006 8.6e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
OOONCIOL_02007 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
OOONCIOL_02008 2e-247 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OOONCIOL_02009 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OOONCIOL_02010 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OOONCIOL_02011 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OOONCIOL_02012 3.7e-40 yabK S Peptide ABC transporter permease
OOONCIOL_02013 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OOONCIOL_02014 6.2e-91 spoVT K stage V sporulation protein
OOONCIOL_02015 5.9e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OOONCIOL_02016 1.8e-273 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
OOONCIOL_02017 2.8e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
OOONCIOL_02018 1.9e-49 yabP S Sporulation protein YabP
OOONCIOL_02019 2.9e-103 yabQ S spore cortex biosynthesis protein
OOONCIOL_02020 4.1e-57 divIC D Septum formation initiator
OOONCIOL_02021 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
OOONCIOL_02024 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
OOONCIOL_02025 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
OOONCIOL_02026 1.4e-184 KLT serine threonine protein kinase
OOONCIOL_02027 2.7e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OOONCIOL_02028 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OOONCIOL_02029 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OOONCIOL_02030 7.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OOONCIOL_02031 2.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OOONCIOL_02032 1.1e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
OOONCIOL_02033 8.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OOONCIOL_02034 2.3e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OOONCIOL_02035 2.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
OOONCIOL_02036 5.5e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
OOONCIOL_02037 1.8e-156 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OOONCIOL_02038 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OOONCIOL_02039 2.4e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OOONCIOL_02040 4.5e-29 yazB K transcriptional
OOONCIOL_02041 7.8e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OOONCIOL_02042 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OOONCIOL_02043 3.4e-39 S COG NOG14552 non supervised orthologous group
OOONCIOL_02045 1.3e-07
OOONCIOL_02048 2e-08
OOONCIOL_02053 7.5e-77 ctsR K Belongs to the CtsR family
OOONCIOL_02054 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
OOONCIOL_02055 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
OOONCIOL_02056 0.0 clpC O Belongs to the ClpA ClpB family
OOONCIOL_02057 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OOONCIOL_02058 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OOONCIOL_02059 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
OOONCIOL_02060 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
OOONCIOL_02061 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
OOONCIOL_02062 1.2e-277 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OOONCIOL_02063 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
OOONCIOL_02064 6.9e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OOONCIOL_02065 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OOONCIOL_02066 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OOONCIOL_02067 4.2e-89 yacP S RNA-binding protein containing a PIN domain
OOONCIOL_02068 8.9e-116 sigH K Belongs to the sigma-70 factor family
OOONCIOL_02069 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OOONCIOL_02070 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
OOONCIOL_02071 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OOONCIOL_02072 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OOONCIOL_02073 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OOONCIOL_02074 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OOONCIOL_02075 3.1e-107 rsmC 2.1.1.172 J Methyltransferase
OOONCIOL_02076 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OOONCIOL_02077 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OOONCIOL_02078 7.5e-86 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OOONCIOL_02079 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
OOONCIOL_02080 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OOONCIOL_02081 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OOONCIOL_02082 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OOONCIOL_02083 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OOONCIOL_02084 4.7e-182 ybaC 3.4.11.5 S Alpha/beta hydrolase family
OOONCIOL_02085 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
OOONCIOL_02086 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OOONCIOL_02087 3e-105 rplD J Forms part of the polypeptide exit tunnel
OOONCIOL_02088 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OOONCIOL_02089 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OOONCIOL_02090 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OOONCIOL_02091 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OOONCIOL_02092 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OOONCIOL_02093 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OOONCIOL_02094 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
OOONCIOL_02095 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OOONCIOL_02096 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OOONCIOL_02097 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OOONCIOL_02098 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OOONCIOL_02099 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OOONCIOL_02100 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OOONCIOL_02101 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OOONCIOL_02102 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OOONCIOL_02103 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OOONCIOL_02104 1.9e-23 rpmD J Ribosomal protein L30
OOONCIOL_02105 4.1e-72 rplO J binds to the 23S rRNA
OOONCIOL_02106 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OOONCIOL_02107 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OOONCIOL_02108 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
OOONCIOL_02109 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OOONCIOL_02110 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
OOONCIOL_02111 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OOONCIOL_02112 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OOONCIOL_02113 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OOONCIOL_02114 4.7e-58 rplQ J Ribosomal protein L17
OOONCIOL_02115 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OOONCIOL_02116 9.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OOONCIOL_02117 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OOONCIOL_02118 4.5e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OOONCIOL_02119 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OOONCIOL_02120 6.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
OOONCIOL_02121 6.9e-144 ybaJ Q Methyltransferase domain
OOONCIOL_02122 4.6e-82 yizA S Damage-inducible protein DinB
OOONCIOL_02123 1.4e-77 ybaK S Protein of unknown function (DUF2521)
OOONCIOL_02124 4.6e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOONCIOL_02125 8.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
OOONCIOL_02126 1.7e-75 gerD
OOONCIOL_02127 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
OOONCIOL_02128 2.7e-132 pdaB 3.5.1.104 G Polysaccharide deacetylase
OOONCIOL_02129 3.4e-39 S COG NOG14552 non supervised orthologous group
OOONCIOL_02130 8.1e-24 S ORF located using Blastx
OOONCIOL_02133 1.6e-08
OOONCIOL_02136 3.4e-39 S COG NOG14552 non supervised orthologous group
OOONCIOL_02137 2.7e-219 glcP G Major Facilitator Superfamily
OOONCIOL_02138 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OOONCIOL_02139 1.1e-175 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
OOONCIOL_02140 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
OOONCIOL_02141 3.5e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
OOONCIOL_02142 9.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
OOONCIOL_02143 4.6e-108 ybbA S Putative esterase
OOONCIOL_02144 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOONCIOL_02145 8.1e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOONCIOL_02146 2e-172 feuA P Iron-uptake system-binding protein
OOONCIOL_02147 8.6e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
OOONCIOL_02148 8.6e-237 ybbC 3.2.1.52 S protein conserved in bacteria
OOONCIOL_02149 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
OOONCIOL_02150 8.9e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
OOONCIOL_02151 1.4e-240 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OOONCIOL_02152 2.9e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OOONCIOL_02153 7.7e-85 ybbJ J acetyltransferase
OOONCIOL_02154 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
OOONCIOL_02160 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
OOONCIOL_02161 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
OOONCIOL_02162 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OOONCIOL_02163 6.3e-223 ybbR S protein conserved in bacteria
OOONCIOL_02164 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OOONCIOL_02165 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OOONCIOL_02166 1.1e-153 V ATPases associated with a variety of cellular activities
OOONCIOL_02167 3.7e-106 S ABC-2 family transporter protein
OOONCIOL_02168 8e-99 ybdN
OOONCIOL_02169 7.1e-132 ybdO S Domain of unknown function (DUF4885)
OOONCIOL_02170 3.6e-162 dkgB S Aldo/keto reductase family
OOONCIOL_02171 2.9e-93 yxaC M effector of murein hydrolase
OOONCIOL_02172 6.9e-52 S LrgA family
OOONCIOL_02173 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
OOONCIOL_02174 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
OOONCIOL_02175 6.1e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
OOONCIOL_02176 4.7e-197 T COG4585 Signal transduction histidine kinase
OOONCIOL_02177 4.6e-109 KT LuxR family transcriptional regulator
OOONCIOL_02178 2.5e-164 V COG1131 ABC-type multidrug transport system, ATPase component
OOONCIOL_02179 4.6e-203 V COG0842 ABC-type multidrug transport system, permease component
OOONCIOL_02180 9.8e-195 V ABC-2 family transporter protein
OOONCIOL_02181 9.2e-23
OOONCIOL_02182 2.5e-75 S Domain of unknown function (DUF4879)
OOONCIOL_02183 5.8e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
OOONCIOL_02184 1.2e-107 yqeB
OOONCIOL_02185 9.2e-40 ybyB
OOONCIOL_02186 5.5e-292 ybeC E amino acid
OOONCIOL_02187 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OOONCIOL_02188 1.7e-259 glpT G -transporter
OOONCIOL_02189 1e-16 S Protein of unknown function (DUF2651)
OOONCIOL_02190 3.3e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
OOONCIOL_02192 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
OOONCIOL_02193 9.2e-32
OOONCIOL_02194 1.2e-82 K Helix-turn-helix XRE-family like proteins
OOONCIOL_02195 6e-194 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OOONCIOL_02196 1.2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OOONCIOL_02197 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OOONCIOL_02198 1.9e-86 ybfM S SNARE associated Golgi protein
OOONCIOL_02199 4.7e-151 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
OOONCIOL_02200 6.1e-42 ybfN
OOONCIOL_02201 9.5e-191 yceA S Belongs to the UPF0176 family
OOONCIOL_02202 9.3e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OOONCIOL_02203 5.6e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OOONCIOL_02204 1.5e-256 mmuP E amino acid
OOONCIOL_02205 6.3e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
OOONCIOL_02206 2.7e-258 agcS E Sodium alanine symporter
OOONCIOL_02207 5.9e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
OOONCIOL_02208 1.1e-205 phoQ 2.7.13.3 T Histidine kinase
OOONCIOL_02209 8.2e-171 glnL T Regulator
OOONCIOL_02210 6.6e-125 ycbJ S Macrolide 2'-phosphotransferase
OOONCIOL_02211 6.9e-25 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
OOONCIOL_02212 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OOONCIOL_02213 1.3e-108 ydfN C nitroreductase
OOONCIOL_02214 8.4e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
OOONCIOL_02215 1.5e-62 mhqP S DoxX
OOONCIOL_02216 7e-56 traF CO Thioredoxin
OOONCIOL_02217 5.6e-62 ycbP S Protein of unknown function (DUF2512)
OOONCIOL_02218 5.3e-77 sleB 3.5.1.28 M Cell wall
OOONCIOL_02219 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
OOONCIOL_02220 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OOONCIOL_02221 1.4e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OOONCIOL_02222 5.5e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OOONCIOL_02223 5.1e-204 ycbU E Selenocysteine lyase
OOONCIOL_02224 1e-241 lmrB EGP the major facilitator superfamily
OOONCIOL_02225 6.5e-99 yxaF K Transcriptional regulator
OOONCIOL_02226 8.7e-196 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
OOONCIOL_02227 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OOONCIOL_02228 2e-194 yccF K DNA-templated transcriptional preinitiation complex assembly
OOONCIOL_02229 6.8e-170 yccK C Aldo keto reductase
OOONCIOL_02230 1.5e-175 ycdA S Domain of unknown function (DUF5105)
OOONCIOL_02231 1.9e-256 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
OOONCIOL_02232 1.3e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
OOONCIOL_02233 1.7e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
OOONCIOL_02234 1e-188 S response regulator aspartate phosphatase
OOONCIOL_02235 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
OOONCIOL_02236 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
OOONCIOL_02237 6.7e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
OOONCIOL_02238 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OOONCIOL_02239 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OOONCIOL_02240 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOONCIOL_02241 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
OOONCIOL_02242 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
OOONCIOL_02243 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
OOONCIOL_02244 9.7e-138 terC P Protein of unknown function (DUF475)
OOONCIOL_02245 0.0 yceG S Putative component of 'biosynthetic module'
OOONCIOL_02246 2.3e-193 yceH P Belongs to the TelA family
OOONCIOL_02247 9e-215 naiP P Uncharacterised MFS-type transporter YbfB
OOONCIOL_02248 3.9e-229 proV 3.6.3.32 E glycine betaine
OOONCIOL_02249 1.6e-138 opuAB P glycine betaine
OOONCIOL_02250 1.5e-163 opuAC E glycine betaine
OOONCIOL_02251 2.8e-210 amhX S amidohydrolase
OOONCIOL_02252 4.9e-228 ycgA S Membrane
OOONCIOL_02253 1.5e-80 ycgB
OOONCIOL_02254 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
OOONCIOL_02255 5.9e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OOONCIOL_02256 8.1e-261 mdr EGP Major facilitator Superfamily
OOONCIOL_02257 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
OOONCIOL_02258 4.7e-114 ycgF E Lysine exporter protein LysE YggA
OOONCIOL_02259 3.8e-150 yqcI S YqcI/YcgG family
OOONCIOL_02260 6.4e-246 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
OOONCIOL_02261 1.3e-113 ycgI S Domain of unknown function (DUF1989)
OOONCIOL_02262 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OOONCIOL_02264 1.6e-108 tmrB S AAA domain
OOONCIOL_02265 2.5e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
OOONCIOL_02266 1.8e-221 G COG0477 Permeases of the major facilitator superfamily
OOONCIOL_02267 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OOONCIOL_02268 6.5e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
OOONCIOL_02269 8.9e-147 ycgL S Predicted nucleotidyltransferase
OOONCIOL_02270 8.7e-170 ycgM E Proline dehydrogenase
OOONCIOL_02271 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OOONCIOL_02272 1.2e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OOONCIOL_02273 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
OOONCIOL_02274 1.3e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
OOONCIOL_02275 1.9e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OOONCIOL_02276 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
OOONCIOL_02277 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OOONCIOL_02278 4.6e-227 yciC S GTPases (G3E family)
OOONCIOL_02279 7.4e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OOONCIOL_02280 4.8e-73 yckC S membrane
OOONCIOL_02281 1.3e-48 S Protein of unknown function (DUF2680)
OOONCIOL_02282 5.1e-66 nin S Competence protein J (ComJ)
OOONCIOL_02283 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
OOONCIOL_02284 1.6e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
OOONCIOL_02285 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
OOONCIOL_02286 2.6e-61 hxlR K transcriptional
OOONCIOL_02287 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOONCIOL_02288 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOONCIOL_02289 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
OOONCIOL_02290 3.4e-140 srfAD Q thioesterase
OOONCIOL_02291 3e-248 bamJ E Aminotransferase class I and II
OOONCIOL_02292 2.2e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
OOONCIOL_02293 1.7e-108 yczE S membrane
OOONCIOL_02294 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OOONCIOL_02295 6.3e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
OOONCIOL_02296 1.2e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
OOONCIOL_02297 3.9e-159 bsdA K LysR substrate binding domain
OOONCIOL_02298 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
OOONCIOL_02299 5.3e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
OOONCIOL_02300 1.7e-37 bsdD 4.1.1.61 S response to toxic substance
OOONCIOL_02301 1.3e-76 yclD
OOONCIOL_02302 1.2e-269 dtpT E amino acid peptide transporter
OOONCIOL_02303 9.2e-277 yclG M Pectate lyase superfamily protein
OOONCIOL_02305 7.8e-294 gerKA EG Spore germination protein
OOONCIOL_02306 5.2e-234 gerKC S spore germination
OOONCIOL_02307 1.1e-195 gerKB F Spore germination protein
OOONCIOL_02308 2.8e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOONCIOL_02309 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OOONCIOL_02310 1.3e-140 yxeM M Belongs to the bacterial solute-binding protein 3 family
OOONCIOL_02311 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
OOONCIOL_02312 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
OOONCIOL_02313 3.2e-217 yxeP 3.5.1.47 E hydrolase activity
OOONCIOL_02314 2.1e-249 yxeQ S MmgE/PrpD family
OOONCIOL_02315 5.2e-119 yclH P ABC transporter
OOONCIOL_02316 1.9e-232 yclI V ABC transporter (permease) YclI
OOONCIOL_02317 1.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOONCIOL_02318 4.1e-259 T PhoQ Sensor
OOONCIOL_02319 1.6e-80 S aspartate phosphatase
OOONCIOL_02321 2.9e-246 lysC 2.7.2.4 E Belongs to the aspartokinase family
OOONCIOL_02322 1.5e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOONCIOL_02323 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOONCIOL_02324 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
OOONCIOL_02325 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
OOONCIOL_02326 6.2e-247 ycnB EGP Major facilitator Superfamily
OOONCIOL_02327 3e-151 ycnC K Transcriptional regulator
OOONCIOL_02328 1.5e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
OOONCIOL_02329 1e-44 ycnE S Monooxygenase
OOONCIOL_02330 1.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
OOONCIOL_02331 1.5e-261 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OOONCIOL_02332 3.2e-218 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OOONCIOL_02333 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OOONCIOL_02334 3.6e-149 glcU U Glucose uptake
OOONCIOL_02335 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOONCIOL_02336 2.3e-97 ycnI S protein conserved in bacteria
OOONCIOL_02337 4.4e-297 ycnJ P protein, homolog of Cu resistance protein CopC
OOONCIOL_02338 9.5e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
OOONCIOL_02339 1.6e-55
OOONCIOL_02340 7.9e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
OOONCIOL_02341 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
OOONCIOL_02342 1.3e-204 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
OOONCIOL_02343 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
OOONCIOL_02345 1e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OOONCIOL_02346 1e-139 ycsF S Belongs to the UPF0271 (lamB) family
OOONCIOL_02347 4.4e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
OOONCIOL_02348 7.4e-149 ycsI S Belongs to the D-glutamate cyclase family
OOONCIOL_02349 2.1e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
OOONCIOL_02350 1.2e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
OOONCIOL_02351 1.3e-129 kipR K Transcriptional regulator
OOONCIOL_02352 6.7e-116 ycsK E anatomical structure formation involved in morphogenesis
OOONCIOL_02354 5.1e-56 yczJ S biosynthesis
OOONCIOL_02355 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
OOONCIOL_02356 1.2e-171 ydhF S Oxidoreductase
OOONCIOL_02357 0.0 mtlR K transcriptional regulator, MtlR
OOONCIOL_02358 5.5e-286 ydaB IQ acyl-CoA ligase
OOONCIOL_02359 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOONCIOL_02360 3e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
OOONCIOL_02361 1.5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OOONCIOL_02362 1.4e-77 ydaG 1.4.3.5 S general stress protein
OOONCIOL_02363 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
OOONCIOL_02364 1.3e-47 ydzA EGP Major facilitator Superfamily
OOONCIOL_02365 4.3e-74 lrpC K Transcriptional regulator
OOONCIOL_02366 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OOONCIOL_02367 1.6e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
OOONCIOL_02368 4.3e-147 ydaK T Diguanylate cyclase, GGDEF domain
OOONCIOL_02369 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
OOONCIOL_02370 2.5e-231 ydaM M Glycosyl transferase family group 2
OOONCIOL_02371 0.0 ydaN S Bacterial cellulose synthase subunit
OOONCIOL_02372 0.0 ydaO E amino acid
OOONCIOL_02373 4.1e-72 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
OOONCIOL_02374 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OOONCIOL_02375 5.3e-64 K acetyltransferase
OOONCIOL_02377 2.8e-57 S Domain of unknown function (DUF4145)
OOONCIOL_02378 1.3e-23
OOONCIOL_02379 4.5e-22
OOONCIOL_02380 4e-23 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOONCIOL_02381 7.7e-85 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OOONCIOL_02382 6.3e-69
OOONCIOL_02383 2.6e-208 S Histidine kinase
OOONCIOL_02385 1.2e-11
OOONCIOL_02387 8.5e-75
OOONCIOL_02388 1.7e-96
OOONCIOL_02389 1.8e-38
OOONCIOL_02390 9.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
OOONCIOL_02392 2.5e-33 ydaT
OOONCIOL_02393 1.2e-70 yvaD S Family of unknown function (DUF5360)
OOONCIOL_02394 7.8e-53 yvaE P Small Multidrug Resistance protein
OOONCIOL_02395 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
OOONCIOL_02397 3.4e-58 ydbB G Cupin domain
OOONCIOL_02398 4.6e-58 ydbC S Domain of unknown function (DUF4937
OOONCIOL_02399 1.2e-154 ydbD P Catalase
OOONCIOL_02400 6.5e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
OOONCIOL_02401 3e-298 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OOONCIOL_02402 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
OOONCIOL_02403 1.9e-223 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OOONCIOL_02404 4e-158 ydbI S AI-2E family transporter
OOONCIOL_02405 6.1e-171 ydbJ V ABC transporter, ATP-binding protein
OOONCIOL_02406 2.2e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OOONCIOL_02407 4.6e-52 ydbL
OOONCIOL_02408 1.7e-202 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
OOONCIOL_02409 1.5e-10 S Fur-regulated basic protein B
OOONCIOL_02410 5.8e-09 S Fur-regulated basic protein A
OOONCIOL_02411 5.3e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OOONCIOL_02412 3.2e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OOONCIOL_02413 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OOONCIOL_02414 1.2e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OOONCIOL_02415 1.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OOONCIOL_02416 1.3e-60 ydbS S Bacterial PH domain
OOONCIOL_02417 1.3e-260 ydbT S Membrane
OOONCIOL_02418 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
OOONCIOL_02419 6.8e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OOONCIOL_02420 5.8e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
OOONCIOL_02421 2.6e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OOONCIOL_02422 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
OOONCIOL_02423 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
OOONCIOL_02424 6.1e-146 rsbR T Positive regulator of sigma-B
OOONCIOL_02425 1.8e-57 rsbS T antagonist
OOONCIOL_02426 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
OOONCIOL_02427 1.7e-187 rsbU 3.1.3.3 KT phosphatase
OOONCIOL_02428 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
OOONCIOL_02429 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
OOONCIOL_02430 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOONCIOL_02431 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
OOONCIOL_02432 0.0 yhgF K COG2183 Transcriptional accessory protein
OOONCIOL_02433 1.7e-14
OOONCIOL_02434 4.3e-58 ydcK S Belongs to the SprT family
OOONCIOL_02442 1.2e-94 ywrO S Flavodoxin-like fold
OOONCIOL_02443 2.3e-150 S Serine aminopeptidase, S33
OOONCIOL_02444 5.7e-229 proP EGP Transporter
OOONCIOL_02445 1e-136 I esterase
OOONCIOL_02446 1.3e-46 ohrB O OsmC-like protein
OOONCIOL_02447 1.4e-48 ohrR K Transcriptional regulator
OOONCIOL_02448 5.4e-86 S Domain of unknown function with cystatin-like fold (DUF4467)
OOONCIOL_02449 1e-72 maoC I N-terminal half of MaoC dehydratase
OOONCIOL_02450 3.2e-64 yyaQ S YjbR
OOONCIOL_02451 4.1e-72 ywnA K Transcriptional regulator
OOONCIOL_02452 5.4e-110 ywnB S NAD(P)H-binding
OOONCIOL_02453 1.4e-30 cspL K Cold shock
OOONCIOL_02454 9.2e-40 yrkD S protein conserved in bacteria
OOONCIOL_02455 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
OOONCIOL_02456 2.2e-17 P Rhodanese Homology Domain
OOONCIOL_02457 5e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
OOONCIOL_02458 3.4e-200 yrkH P Rhodanese Homology Domain
OOONCIOL_02459 3.5e-35 yrkI O Belongs to the sulfur carrier protein TusA family
OOONCIOL_02460 7.3e-117 yrkJ S membrane transporter protein
OOONCIOL_02461 3.7e-117 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
OOONCIOL_02462 7.5e-103 S Protein of unknown function (DUF2812)
OOONCIOL_02463 2.4e-50 K Transcriptional regulator PadR-like family
OOONCIOL_02464 2.3e-181 S Patatin-like phospholipase
OOONCIOL_02465 2.7e-82 S DinB superfamily
OOONCIOL_02466 3.3e-116 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
OOONCIOL_02467 2.7e-67 K COG1802 Transcriptional regulators
OOONCIOL_02468 1.7e-39 yabJ 3.5.99.10 J Endoribonuclease L-PSP
OOONCIOL_02469 2.2e-142 sdaC E Serine transporter
OOONCIOL_02470 9.7e-152 E Peptidase dimerisation domain
OOONCIOL_02471 7.6e-126 rhaS5 K helix_turn_helix, arabinose operon control protein
OOONCIOL_02472 1.5e-175 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OOONCIOL_02473 6.5e-233 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OOONCIOL_02474 2.6e-191 ydeG EGP Major facilitator superfamily
OOONCIOL_02475 2.9e-27 3.6.1.55 F Belongs to the Nudix hydrolase family
OOONCIOL_02478 6.6e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
OOONCIOL_02479 1.2e-09 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OOONCIOL_02480 8.4e-168 czcD P COG1230 Co Zn Cd efflux system component
OOONCIOL_02481 7.5e-194 trkA P Oxidoreductase
OOONCIOL_02484 1.8e-14 ykkA S Protein of unknown function (DUF664)
OOONCIOL_02485 9.6e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
OOONCIOL_02487 6.9e-195 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
OOONCIOL_02488 2.6e-51 ydeH
OOONCIOL_02489 6.4e-70 S Sodium Bile acid symporter family
OOONCIOL_02490 5.4e-66 S Sodium Bile acid symporter family
OOONCIOL_02491 3.8e-201 adhA 1.1.1.1 C alcohol dehydrogenase
OOONCIOL_02492 3.6e-67 yraB K helix_turn_helix, mercury resistance
OOONCIOL_02493 1.1e-223 mleN_2 C antiporter
OOONCIOL_02494 1.4e-256 K helix_turn_helix gluconate operon transcriptional repressor
OOONCIOL_02495 1.1e-110 paiB K Transcriptional regulator
OOONCIOL_02497 4.5e-174 ydeR EGP Major facilitator Superfamily
OOONCIOL_02498 6e-100 ydeS K Transcriptional regulator
OOONCIOL_02499 1.4e-47 yraD M Spore coat protein
OOONCIOL_02500 3.1e-24 yraE
OOONCIOL_02501 3.3e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OOONCIOL_02502 8.4e-63 yraF M Spore coat protein
OOONCIOL_02503 1.3e-35 yraG
OOONCIOL_02504 4.3e-215 ydfH 2.7.13.3 T Histidine kinase
OOONCIOL_02505 6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OOONCIOL_02506 0.0 ydfJ S drug exporters of the RND superfamily
OOONCIOL_02507 1.8e-133 puuD S Peptidase C26
OOONCIOL_02508 1.8e-298 expZ S ABC transporter
OOONCIOL_02509 1.1e-97 ynaD J Acetyltransferase (GNAT) domain
OOONCIOL_02510 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
OOONCIOL_02511 1.9e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OOONCIOL_02512 5.1e-210 tcaB EGP Major facilitator Superfamily
OOONCIOL_02513 3.7e-224 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OOONCIOL_02514 1.9e-155 K Helix-turn-helix XRE-family like proteins
OOONCIOL_02515 9.4e-122 ydhB S membrane transporter protein
OOONCIOL_02516 2.2e-81 bltD 2.3.1.57 K FR47-like protein
OOONCIOL_02517 2.2e-148 bltR K helix_turn_helix, mercury resistance
OOONCIOL_02518 7.6e-147 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OOONCIOL_02519 1.3e-111 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
OOONCIOL_02520 6.4e-145 ycgJ_1 Q ubiE/COQ5 methyltransferase family
OOONCIOL_02521 3e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
OOONCIOL_02522 6.9e-119 ydhC K FCD
OOONCIOL_02523 4.6e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OOONCIOL_02526 1.4e-261 pbpE V Beta-lactamase
OOONCIOL_02528 2.5e-98 ydhK M Protein of unknown function (DUF1541)
OOONCIOL_02529 1.1e-193 pbuE EGP Major facilitator Superfamily
OOONCIOL_02530 1.3e-131 ydhQ K UTRA
OOONCIOL_02531 9.9e-118 K FCD
OOONCIOL_02532 8.2e-216 yeaN P COG2807 Cyanate permease
OOONCIOL_02533 7.7e-49 sugE P Small Multidrug Resistance protein
OOONCIOL_02534 2.3e-51 ykkC P Small Multidrug Resistance protein
OOONCIOL_02535 2.9e-102 yvdT K Transcriptional regulator
OOONCIOL_02536 2.1e-296 yveA E amino acid
OOONCIOL_02537 1.9e-163 ydhU P Catalase
OOONCIOL_02538 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
OOONCIOL_02539 7.5e-183 yhfP 1.1.1.1 C Quinone oxidoreductase
OOONCIOL_02540 2.7e-250 iolT EGP Major facilitator Superfamily
OOONCIOL_02543 2.8e-13 S ORF located using Blastx
OOONCIOL_02544 7.8e-08
OOONCIOL_02546 1.9e-183 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OOONCIOL_02547 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
OOONCIOL_02548 5.5e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
OOONCIOL_02549 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OOONCIOL_02550 9.6e-189 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OOONCIOL_02551 0.0 ydiF S ABC transporter
OOONCIOL_02552 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
OOONCIOL_02553 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OOONCIOL_02554 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OOONCIOL_02555 1.8e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OOONCIOL_02556 1.7e-27 ydiK S Domain of unknown function (DUF4305)
OOONCIOL_02557 4.3e-127 ydiL S CAAX protease self-immunity
OOONCIOL_02558 6.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OOONCIOL_02559 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OOONCIOL_02560 3.1e-71 E Peptidase dimerisation domain
OOONCIOL_02561 3.9e-50 S Lantibiotic dehydratase, C terminus
OOONCIOL_02562 4.1e-25 C coenzyme F420-1:gamma-L-glutamate ligase activity
OOONCIOL_02564 9.9e-102 H YcaO cyclodehydratase, ATP-ad Mg2+-binding
OOONCIOL_02565 4.3e-39 cobT 1.13.11.79, 2.4.2.21 C coenzyme F420-1:gamma-L-glutamate ligase activity
OOONCIOL_02566 1.8e-28 C Nitroreductase family
OOONCIOL_02567 1e-07 moeB 2.7.7.73, 2.7.7.80 H molybdopterin biosynthesis protein moeB
OOONCIOL_02568 1.6e-78 yvfR V ABC transporter
OOONCIOL_02569 1.7e-33 yvfS V Transporter
OOONCIOL_02570 0.0 K NB-ARC domain
OOONCIOL_02571 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
OOONCIOL_02572 4.9e-249 gutA G MFS/sugar transport protein
OOONCIOL_02573 3.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
OOONCIOL_02574 3.6e-30 yjdJ S Domain of unknown function (DUF4306)
OOONCIOL_02575 1.3e-112 pspA KT Phage shock protein A
OOONCIOL_02576 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OOONCIOL_02577 3.8e-118 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
OOONCIOL_02578 2.4e-144 ydjI S virion core protein (lumpy skin disease virus)
OOONCIOL_02579 0.0 yrhL I Acyltransferase family
OOONCIOL_02580 1.4e-145 rsiV S Protein of unknown function (DUF3298)
OOONCIOL_02581 2.8e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
OOONCIOL_02582 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OOONCIOL_02583 1.2e-61 ydjM M Lytic transglycolase
OOONCIOL_02584 2e-133 ydjN U Involved in the tonB-independent uptake of proteins
OOONCIOL_02586 7.2e-35 ydjO S Cold-inducible protein YdjO
OOONCIOL_02587 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
OOONCIOL_02588 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
OOONCIOL_02589 3e-176 yeaC S COG0714 MoxR-like ATPases
OOONCIOL_02590 1.9e-206 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
OOONCIOL_02591 0.0 yebA E COG1305 Transglutaminase-like enzymes
OOONCIOL_02592 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OOONCIOL_02593 5e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
OOONCIOL_02594 3e-249 S Domain of unknown function (DUF4179)
OOONCIOL_02595 8.1e-209 pbuG S permease
OOONCIOL_02596 1.5e-125 yebC M Membrane
OOONCIOL_02598 7.5e-92 yebE S UPF0316 protein
OOONCIOL_02599 5.5e-29 yebG S NETI protein
OOONCIOL_02600 6.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OOONCIOL_02601 3e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OOONCIOL_02602 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OOONCIOL_02603 3.8e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
OOONCIOL_02604 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OOONCIOL_02605 7.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OOONCIOL_02606 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OOONCIOL_02607 1.2e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OOONCIOL_02608 1.9e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
OOONCIOL_02609 9.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OOONCIOL_02610 1.9e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
OOONCIOL_02611 5.3e-234 purD 6.3.4.13 F Belongs to the GARS family
OOONCIOL_02612 5.7e-25 S Protein of unknown function (DUF2892)
OOONCIOL_02613 0.0 yerA 3.5.4.2 F adenine deaminase
OOONCIOL_02614 1.5e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
OOONCIOL_02615 2.4e-50 yerC S protein conserved in bacteria
OOONCIOL_02616 4.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
OOONCIOL_02617 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OOONCIOL_02618 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OOONCIOL_02619 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OOONCIOL_02620 2e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
OOONCIOL_02621 7.5e-191 yerI S homoserine kinase type II (protein kinase fold)
OOONCIOL_02622 1.3e-120 sapB S MgtC SapB transporter
OOONCIOL_02623 1.4e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OOONCIOL_02624 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OOONCIOL_02625 4.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OOONCIOL_02626 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OOONCIOL_02627 1.9e-150 yerO K Transcriptional regulator
OOONCIOL_02628 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OOONCIOL_02629 6.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OOONCIOL_02630 1.9e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OOONCIOL_02631 4.5e-21
OOONCIOL_02632 6.1e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
OOONCIOL_02633 5e-138 cylB V ABC-2 type transporter
OOONCIOL_02634 1.5e-37 S Protein of unknown function, DUF600
OOONCIOL_02635 2.7e-85 S Protein of unknown function, DUF600
OOONCIOL_02636 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
OOONCIOL_02637 1.1e-20
OOONCIOL_02638 9.4e-127 yeeN K transcriptional regulatory protein
OOONCIOL_02640 1.5e-107 aadK G Streptomycin adenylyltransferase
OOONCIOL_02641 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
OOONCIOL_02642 1.3e-44 cotJB S CotJB protein
OOONCIOL_02643 8.9e-104 cotJC P Spore Coat
OOONCIOL_02644 5e-93 yesJ K Acetyltransferase (GNAT) family
OOONCIOL_02646 2.1e-120 yetF S membrane
OOONCIOL_02647 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
OOONCIOL_02648 7.5e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OOONCIOL_02649 3.7e-154 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OOONCIOL_02650 3.4e-22 yezD S Uncharacterized small protein (DUF2292)
OOONCIOL_02651 2.6e-54 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
OOONCIOL_02652 2.4e-105 yetJ S Belongs to the BI1 family
OOONCIOL_02654 8e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
OOONCIOL_02655 2.3e-204 yetM CH FAD binding domain
OOONCIOL_02656 3.4e-197 yetN S Protein of unknown function (DUF3900)
OOONCIOL_02657 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OOONCIOL_02659 5.3e-50 MA20_23570 K Winged helix DNA-binding domain
OOONCIOL_02660 1.5e-161 V ATPases associated with a variety of cellular activities
OOONCIOL_02661 1.3e-126 V ABC-2 type transporter
OOONCIOL_02662 5.1e-72 S protein homooligomerization
OOONCIOL_02663 6.6e-125
OOONCIOL_02664 9.8e-183 S ATP diphosphatase activity
OOONCIOL_02665 1.1e-261 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
OOONCIOL_02666 8.6e-153 sagB C Nitroreductase family
OOONCIOL_02667 2.8e-112 S CAAX protease self-immunity
OOONCIOL_02668 2.1e-143 2.1.1.163, 2.1.1.201 Q methyltransferase
OOONCIOL_02669 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OOONCIOL_02670 1.8e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
OOONCIOL_02671 2.4e-172 yfnG 4.2.1.45 M dehydratase
OOONCIOL_02672 3e-178 yfnF M Nucleotide-diphospho-sugar transferase
OOONCIOL_02673 1.4e-220 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
OOONCIOL_02674 1.5e-185 yfnD M Nucleotide-diphospho-sugar transferase
OOONCIOL_02675 6.8e-218 fsr P COG0477 Permeases of the major facilitator superfamily
OOONCIOL_02676 2.8e-244 yfnA E amino acid
OOONCIOL_02677 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OOONCIOL_02678 7.5e-107 yfmS NT chemotaxis protein
OOONCIOL_02679 1.5e-166 IQ Enoyl-(Acyl carrier protein) reductase
OOONCIOL_02680 6.1e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OOONCIOL_02681 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OOONCIOL_02682 1.8e-69 yfmP K transcriptional
OOONCIOL_02683 7.5e-206 yfmO EGP Major facilitator Superfamily
OOONCIOL_02684 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OOONCIOL_02685 4.3e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
OOONCIOL_02686 2.8e-44 yfmK 2.3.1.128 K acetyltransferase
OOONCIOL_02687 1.8e-187 yfmJ S N-terminal domain of oxidoreductase
OOONCIOL_02688 4.5e-24 S Protein of unknown function (DUF3212)
OOONCIOL_02689 1.3e-57 yflT S Heat induced stress protein YflT
OOONCIOL_02690 1.7e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
OOONCIOL_02691 3.9e-233 yflS P Sodium:sulfate symporter transmembrane region
OOONCIOL_02692 5.2e-27 Q PFAM Collagen triple helix
OOONCIOL_02695 6.8e-24 M1-820 Q Collagen triple helix repeat (20 copies)
OOONCIOL_02696 0.0 ywpD T PhoQ Sensor
OOONCIOL_02697 1.3e-151 M1-574 T Transcriptional regulatory protein, C terminal
OOONCIOL_02698 0.0 M1-568 M cell wall anchor domain
OOONCIOL_02699 4.6e-80 srtA 3.4.22.70 M Sortase family
OOONCIOL_02700 3.1e-271 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OOONCIOL_02701 5.8e-118 citT T response regulator
OOONCIOL_02702 6.6e-176 yflP S Tripartite tricarboxylate transporter family receptor
OOONCIOL_02703 3.6e-225 citM C Citrate transporter
OOONCIOL_02704 9e-147 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
OOONCIOL_02705 2.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OOONCIOL_02706 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OOONCIOL_02707 1.3e-122 yflK S protein conserved in bacteria
OOONCIOL_02708 1.5e-14 yflJ S Protein of unknown function (DUF2639)
OOONCIOL_02709 7e-19 yflI
OOONCIOL_02710 3.1e-50 yflH S Protein of unknown function (DUF3243)
OOONCIOL_02711 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
OOONCIOL_02712 1.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
OOONCIOL_02713 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
OOONCIOL_02714 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OOONCIOL_02715 1.5e-62 yhdN S Domain of unknown function (DUF1992)
OOONCIOL_02716 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
OOONCIOL_02717 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
OOONCIOL_02718 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
OOONCIOL_02719 1.5e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OOONCIOL_02720 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OOONCIOL_02721 1.3e-128 treR K transcriptional
OOONCIOL_02722 3.4e-123 yfkO C nitroreductase
OOONCIOL_02723 8.7e-123 yibF S YibE/F-like protein
OOONCIOL_02724 5.5e-198 yibE S YibE/F-like protein
OOONCIOL_02725 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
OOONCIOL_02726 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
OOONCIOL_02727 6.4e-185 K helix_turn _helix lactose operon repressor
OOONCIOL_02728 1.2e-163 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OOONCIOL_02729 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
OOONCIOL_02730 8.1e-192 ydiM EGP Major facilitator Superfamily
OOONCIOL_02731 2.7e-29 yfkK S Belongs to the UPF0435 family
OOONCIOL_02732 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OOONCIOL_02733 1e-51 yfkI S gas vesicle protein
OOONCIOL_02734 7.6e-144 yihY S Belongs to the UPF0761 family
OOONCIOL_02735 2.5e-07
OOONCIOL_02736 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
OOONCIOL_02737 2.2e-185 cax P COG0387 Ca2 H antiporter
OOONCIOL_02738 1.6e-143 yfkD S YfkD-like protein
OOONCIOL_02739 4e-145 yfkC M Mechanosensitive ion channel
OOONCIOL_02740 3.3e-219 yfkA S YfkB-like domain
OOONCIOL_02741 4.9e-27 yfjT
OOONCIOL_02742 9e-155 pdaA G deacetylase
OOONCIOL_02743 5.7e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
OOONCIOL_02744 3.3e-30
OOONCIOL_02745 8.5e-184 corA P Mediates influx of magnesium ions
OOONCIOL_02746 3.7e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OOONCIOL_02747 6.2e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OOONCIOL_02748 2.3e-44 S YfzA-like protein
OOONCIOL_02749 7.9e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OOONCIOL_02750 6.1e-91 yfjM S Psort location Cytoplasmic, score
OOONCIOL_02751 2.2e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OOONCIOL_02752 6.8e-187 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OOONCIOL_02753 4.9e-213 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OOONCIOL_02754 9.5e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OOONCIOL_02755 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OOONCIOL_02756 4.2e-15 sspH S Belongs to the SspH family
OOONCIOL_02757 2.2e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OOONCIOL_02758 5.1e-139 glvR F Helix-turn-helix domain, rpiR family
OOONCIOL_02759 3.2e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OOONCIOL_02760 4.5e-308 yfiB3 V ABC transporter
OOONCIOL_02761 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
OOONCIOL_02762 9.2e-63 mhqP S DoxX
OOONCIOL_02763 1.7e-159 yfiE 1.13.11.2 S glyoxalase
OOONCIOL_02764 8.8e-165 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OOONCIOL_02765 6.6e-96 padR K transcriptional
OOONCIOL_02766 7.9e-111 1.6.5.2 S NADPH-dependent FMN reductase
OOONCIOL_02767 2.7e-178 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OOONCIOL_02768 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
OOONCIOL_02769 2.9e-44 yrdF K ribonuclease inhibitor
OOONCIOL_02770 2.2e-96 yfiT S Belongs to the metal hydrolase YfiT family
OOONCIOL_02771 4.3e-289 yfiU EGP Major facilitator Superfamily
OOONCIOL_02772 6.2e-82 yfiV K transcriptional
OOONCIOL_02773 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OOONCIOL_02774 7.2e-161 yfhB 5.3.3.17 S PhzF family
OOONCIOL_02775 1.7e-105 yfhC C nitroreductase
OOONCIOL_02776 2.1e-25 yfhD S YfhD-like protein
OOONCIOL_02778 1.3e-165 yfhF S nucleoside-diphosphate sugar epimerase
OOONCIOL_02779 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
OOONCIOL_02780 2.5e-52 yfhH S Protein of unknown function (DUF1811)
OOONCIOL_02781 1.1e-204 yfhI EGP Major facilitator Superfamily
OOONCIOL_02783 5.3e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
OOONCIOL_02784 2.2e-44 yfhJ S WVELL protein
OOONCIOL_02785 5.9e-94 batE T Bacterial SH3 domain homologues
OOONCIOL_02786 7e-32 yfhL S SdpI/YhfL protein family
OOONCIOL_02787 2.2e-170 yfhM S Alpha/beta hydrolase family
OOONCIOL_02788 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OOONCIOL_02789 0.0 yfhO S Bacterial membrane protein YfhO
OOONCIOL_02790 1e-184 yfhP S membrane-bound metal-dependent
OOONCIOL_02791 4.8e-207 mutY L A G-specific
OOONCIOL_02792 3.1e-36 yfhS
OOONCIOL_02793 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOONCIOL_02795 1.5e-37 ygaB S YgaB-like protein
OOONCIOL_02796 2.2e-104 ygaC J Belongs to the UPF0374 family
OOONCIOL_02797 3.5e-300 ygaD V ABC transporter
OOONCIOL_02798 2.7e-178 ygaE S Membrane
OOONCIOL_02799 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OOONCIOL_02800 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
OOONCIOL_02801 1.8e-80 perR P Belongs to the Fur family
OOONCIOL_02802 3.3e-56 ygzB S UPF0295 protein
OOONCIOL_02803 1.1e-164 ygxA S Nucleotidyltransferase-like
OOONCIOL_02804 4.8e-23 S ORF located using Blastx
OOONCIOL_02809 7.8e-08
OOONCIOL_02817 1.6e-08
OOONCIOL_02821 3.4e-20 C Na+/H+ antiporter family
OOONCIOL_02822 1e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
OOONCIOL_02823 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OOONCIOL_02824 1.5e-263 ygaK C Berberine and berberine like
OOONCIOL_02826 7.5e-231 oppA5 E PFAM extracellular solute-binding protein family 5
OOONCIOL_02827 2.1e-137 appB P Binding-protein-dependent transport system inner membrane component
OOONCIOL_02828 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOONCIOL_02829 4.1e-133 oppD3 P Belongs to the ABC transporter superfamily
OOONCIOL_02830 5.3e-133 oppF3 E Belongs to the ABC transporter superfamily
OOONCIOL_02831 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OOONCIOL_02832 2.5e-180 S Amidohydrolase
OOONCIOL_02833 6.7e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
OOONCIOL_02834 1.7e-179 ssuA M Sulfonate ABC transporter
OOONCIOL_02835 7.5e-144 ssuC P ABC transporter (permease)
OOONCIOL_02836 2.9e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
OOONCIOL_02837 1.2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OOONCIOL_02838 8.6e-81 ygaO
OOONCIOL_02839 4.8e-23 K Transcriptional regulator
OOONCIOL_02841 9.4e-107 yhzB S B3/4 domain
OOONCIOL_02842 7.8e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OOONCIOL_02843 1.4e-173 yhbB S Putative amidase domain
OOONCIOL_02844 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OOONCIOL_02845 3e-108 yhbD K Protein of unknown function (DUF4004)
OOONCIOL_02846 1.8e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
OOONCIOL_02847 2.1e-62 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
OOONCIOL_02849 0.0 prkA T Ser protein kinase
OOONCIOL_02850 3.9e-215 yhbH S Belongs to the UPF0229 family
OOONCIOL_02851 4.6e-74 yhbI K DNA-binding transcription factor activity
OOONCIOL_02852 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
OOONCIOL_02853 8.4e-285 yhcA EGP Major facilitator Superfamily
OOONCIOL_02854 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
OOONCIOL_02855 3.8e-55 yhcC
OOONCIOL_02856 4.8e-52
OOONCIOL_02857 6.1e-61 yhcF K Transcriptional regulator
OOONCIOL_02858 5.7e-124 yhcG V ABC transporter, ATP-binding protein
OOONCIOL_02859 1.7e-165 yhcH V ABC transporter, ATP-binding protein
OOONCIOL_02860 1.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OOONCIOL_02861 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
OOONCIOL_02862 7.5e-144 metQ M Belongs to the nlpA lipoprotein family
OOONCIOL_02863 2.5e-184 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
OOONCIOL_02864 1.1e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OOONCIOL_02865 7.2e-53 yhcM
OOONCIOL_02866 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OOONCIOL_02867 2.2e-160 yhcP
OOONCIOL_02868 1.2e-112 yhcQ M Spore coat protein
OOONCIOL_02869 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
OOONCIOL_02870 2.2e-105 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
OOONCIOL_02871 4e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OOONCIOL_02872 1.3e-69 yhcU S Family of unknown function (DUF5365)
OOONCIOL_02873 9.9e-68 yhcV S COG0517 FOG CBS domain
OOONCIOL_02874 1.9e-124 yhcW 5.4.2.6 S hydrolase
OOONCIOL_02875 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OOONCIOL_02876 2.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OOONCIOL_02877 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OOONCIOL_02878 7.7e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
OOONCIOL_02879 1.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OOONCIOL_02880 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OOONCIOL_02881 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
OOONCIOL_02882 8.5e-70 yhcY 2.7.13.3 T Histidine kinase
OOONCIOL_02883 1.1e-35 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OOONCIOL_02884 3.3e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
OOONCIOL_02885 2.5e-39 yhdB S YhdB-like protein
OOONCIOL_02886 1.1e-53 yhdC S Protein of unknown function (DUF3889)
OOONCIOL_02887 2.9e-215 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OOONCIOL_02888 1.6e-73 nsrR K Transcriptional regulator
OOONCIOL_02889 3.1e-244 ygxB M Conserved TM helix
OOONCIOL_02890 1.8e-270 ycgB S Stage V sporulation protein R
OOONCIOL_02891 1.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
OOONCIOL_02892 3.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OOONCIOL_02893 1.3e-162 citR K Transcriptional regulator
OOONCIOL_02894 1.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
OOONCIOL_02895 8.6e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOONCIOL_02896 1.2e-250 yhdG E amino acid
OOONCIOL_02897 2.9e-198 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OOONCIOL_02898 8.1e-45 yhdK S Sigma-M inhibitor protein
OOONCIOL_02899 1.3e-201 yhdL S Sigma factor regulator N-terminal
OOONCIOL_02900 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
OOONCIOL_02901 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OOONCIOL_02902 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OOONCIOL_02903 2.8e-70 cueR K transcriptional
OOONCIOL_02904 1.9e-225 yhdR 2.6.1.1 E Aminotransferase
OOONCIOL_02905 9.5e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OOONCIOL_02906 6e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
OOONCIOL_02907 1.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OOONCIOL_02908 9.7e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OOONCIOL_02909 7.2e-127 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OOONCIOL_02911 1.3e-204 yhdY M Mechanosensitive ion channel
OOONCIOL_02912 2.9e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
OOONCIOL_02913 1.1e-155 yheN G deacetylase
OOONCIOL_02914 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
OOONCIOL_02915 3e-87 pksA K Transcriptional regulator
OOONCIOL_02916 1.8e-93 ymcC S Membrane
OOONCIOL_02917 6.2e-85 T universal stress protein
OOONCIOL_02919 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
OOONCIOL_02920 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
OOONCIOL_02921 1.6e-111 yheG GM NAD(P)H-binding
OOONCIOL_02923 1.3e-28 sspB S spore protein
OOONCIOL_02924 2.2e-36 yheE S Family of unknown function (DUF5342)
OOONCIOL_02925 1.5e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
OOONCIOL_02926 3.4e-213 yheC HJ YheC/D like ATP-grasp
OOONCIOL_02927 3.6e-205 yheB S Belongs to the UPF0754 family
OOONCIOL_02928 4.4e-53 yheA S Belongs to the UPF0342 family
OOONCIOL_02929 8.5e-199 yhaZ L DNA alkylation repair enzyme
OOONCIOL_02930 4.7e-157 yhaX S haloacid dehalogenase-like hydrolase
OOONCIOL_02931 2.1e-293 hemZ H coproporphyrinogen III oxidase
OOONCIOL_02932 2.7e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
OOONCIOL_02933 3.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
OOONCIOL_02934 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
OOONCIOL_02936 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
OOONCIOL_02937 2.8e-14 S YhzD-like protein
OOONCIOL_02938 4.4e-166 yhaQ S ABC transporter, ATP-binding protein
OOONCIOL_02939 1.2e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
OOONCIOL_02940 2e-233 yhaO L DNA repair exonuclease
OOONCIOL_02941 0.0 yhaN L AAA domain
OOONCIOL_02942 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
OOONCIOL_02943 1.8e-31 yhaL S Sporulation protein YhaL
OOONCIOL_02944 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OOONCIOL_02945 7e-95 yhaK S Putative zincin peptidase
OOONCIOL_02946 9.9e-55 yhaI S Protein of unknown function (DUF1878)
OOONCIOL_02947 8.6e-113 hpr K Negative regulator of protease production and sporulation
OOONCIOL_02948 6.2e-39 yhaH S YtxH-like protein
OOONCIOL_02949 2e-17
OOONCIOL_02950 1.4e-76 trpP S Tryptophan transporter TrpP
OOONCIOL_02951 6e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OOONCIOL_02952 4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
OOONCIOL_02953 1.1e-135 ecsA V transporter (ATP-binding protein)
OOONCIOL_02954 5.5e-220 ecsB U ABC transporter
OOONCIOL_02955 4e-122 ecsC S EcsC protein family
OOONCIOL_02956 2e-222 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OOONCIOL_02957 1.2e-124 yhfA C membrane
OOONCIOL_02958 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
OOONCIOL_02959 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OOONCIOL_02960 9.5e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OOONCIOL_02961 9.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
OOONCIOL_02962 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OOONCIOL_02964 3.2e-101 yhgD K Transcriptional regulator
OOONCIOL_02965 3.7e-241 yhgE S YhgE Pip N-terminal domain protein
OOONCIOL_02966 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OOONCIOL_02968 2.5e-197 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
OOONCIOL_02969 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OOONCIOL_02970 7.9e-11 yhfH S YhfH-like protein
OOONCIOL_02971 2.2e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
OOONCIOL_02972 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
OOONCIOL_02973 8.8e-108 yhfK GM NmrA-like family
OOONCIOL_02974 4.1e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OOONCIOL_02975 1.9e-65 yhfM
OOONCIOL_02976 3.6e-235 yhfN 3.4.24.84 O Peptidase M48
OOONCIOL_02977 2.2e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
OOONCIOL_02978 6.3e-149 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
OOONCIOL_02979 4.4e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
OOONCIOL_02980 6.7e-201 vraB 2.3.1.9 I Belongs to the thiolase family
OOONCIOL_02981 2.3e-278 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OOONCIOL_02982 3.5e-89 bioY S BioY family
OOONCIOL_02983 3.1e-197 hemAT NT chemotaxis protein
OOONCIOL_02984 3.5e-296 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
OOONCIOL_02985 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOONCIOL_02986 5.4e-31 yhzC S IDEAL
OOONCIOL_02987 1.9e-109 comK K Competence transcription factor
OOONCIOL_02988 3.3e-67 frataxin S Domain of unknown function (DU1801)
OOONCIOL_02989 4.2e-62 frataxin S Domain of unknown function (DU1801)
OOONCIOL_02990 8.7e-125 yrpD S Domain of unknown function, YrpD
OOONCIOL_02991 1.6e-42 yhjA S Excalibur calcium-binding domain
OOONCIOL_02992 3.3e-47 S Belongs to the UPF0145 family
OOONCIOL_02993 3.8e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OOONCIOL_02994 3.1e-27 yhjC S Protein of unknown function (DUF3311)
OOONCIOL_02995 5e-60 yhjD
OOONCIOL_02996 7.7e-109 yhjE S SNARE associated Golgi protein
OOONCIOL_02997 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
OOONCIOL_02999 9.2e-270 yhjG CH FAD binding domain
OOONCIOL_03000 8.4e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
OOONCIOL_03001 5.3e-188 abrB S membrane
OOONCIOL_03002 8.7e-202 blt EGP Major facilitator Superfamily
OOONCIOL_03003 1.1e-107 K QacR-like protein, C-terminal region
OOONCIOL_03004 2.2e-93 yhjR S Rubrerythrin
OOONCIOL_03005 2.5e-119 ydfS S Protein of unknown function (DUF421)
OOONCIOL_03006 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
OOONCIOL_03007 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OOONCIOL_03008 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
OOONCIOL_03009 0.0 sbcC L COG0419 ATPase involved in DNA repair
OOONCIOL_03010 1.3e-50 yisB V COG1403 Restriction endonuclease
OOONCIOL_03011 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
OOONCIOL_03012 1.1e-63 gerPE S Spore germination protein GerPE
OOONCIOL_03013 3.1e-23 gerPD S Spore germination protein
OOONCIOL_03014 1.4e-62 gerPC S Spore germination protein
OOONCIOL_03015 1.8e-34 gerPB S cell differentiation
OOONCIOL_03016 8.4e-34 gerPA S Spore germination protein
OOONCIOL_03017 4.8e-07 yisI S Spo0E like sporulation regulatory protein
OOONCIOL_03018 5.1e-170 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OOONCIOL_03019 3.2e-59 yisL S UPF0344 protein
OOONCIOL_03020 7.6e-97 yisN S Protein of unknown function (DUF2777)
OOONCIOL_03021 0.0 asnO 6.3.5.4 E Asparagine synthase
OOONCIOL_03022 1.1e-130 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
OOONCIOL_03023 1.5e-245 yisQ V Mate efflux family protein
OOONCIOL_03024 2.3e-159 yisR K Transcriptional regulator
OOONCIOL_03025 4.1e-144 purR K helix_turn _helix lactose operon repressor
OOONCIOL_03026 7.6e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
OOONCIOL_03027 9.8e-83 yisT S DinB family
OOONCIOL_03028 1.6e-69 mcbG S Pentapeptide repeats (9 copies)
OOONCIOL_03029 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
OOONCIOL_03030 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
OOONCIOL_03031 6.6e-55 yajQ S Belongs to the UPF0234 family
OOONCIOL_03032 7.6e-160 cvfB S protein conserved in bacteria
OOONCIOL_03033 2.2e-171 yufN S ABC transporter substrate-binding protein PnrA-like
OOONCIOL_03034 1.7e-232 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
OOONCIOL_03036 4.6e-157 yitS S protein conserved in bacteria
OOONCIOL_03037 1.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
OOONCIOL_03038 5.5e-80 ipi S Intracellular proteinase inhibitor
OOONCIOL_03039 4.4e-26 S Protein of unknown function (DUF3813)
OOONCIOL_03040 3.5e-07
OOONCIOL_03041 4.3e-152 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OOONCIOL_03042 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
OOONCIOL_03043 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
OOONCIOL_03044 4.6e-73 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
OOONCIOL_03045 1.5e-272 yitY C D-arabinono-1,4-lactone oxidase
OOONCIOL_03046 1.2e-89 norB G Major Facilitator Superfamily
OOONCIOL_03047 1.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OOONCIOL_03048 6.7e-226 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OOONCIOL_03049 5.4e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
OOONCIOL_03050 4.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
OOONCIOL_03051 2e-202 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OOONCIOL_03052 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
OOONCIOL_03053 7.8e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OOONCIOL_03054 1.2e-27 yjzC S YjzC-like protein
OOONCIOL_03055 3.3e-23 yjzD S Protein of unknown function (DUF2929)
OOONCIOL_03056 3.2e-138 yjaU I carboxylic ester hydrolase activity
OOONCIOL_03057 8.8e-104 yjaV
OOONCIOL_03058 2.7e-165 med S Transcriptional activator protein med
OOONCIOL_03059 1.1e-26 comZ S ComZ
OOONCIOL_03060 1e-31 yjzB
OOONCIOL_03061 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OOONCIOL_03062 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OOONCIOL_03063 5.6e-149 yjaZ O Zn-dependent protease
OOONCIOL_03064 4.8e-182 appD P Belongs to the ABC transporter superfamily
OOONCIOL_03065 5.9e-188 appF E Belongs to the ABC transporter superfamily
OOONCIOL_03066 4e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
OOONCIOL_03067 1.2e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOONCIOL_03068 6.1e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOONCIOL_03069 1.7e-86 2.1.1.265 H Tellurite resistance protein TehB
OOONCIOL_03070 2.1e-140 EGP Transmembrane secretion effector
OOONCIOL_03071 1.2e-145 yjbA S Belongs to the UPF0736 family
OOONCIOL_03072 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
OOONCIOL_03073 0.0 oppA E ABC transporter substrate-binding protein
OOONCIOL_03074 4.4e-130 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOONCIOL_03075 1.7e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOONCIOL_03076 2.7e-202 oppD P Belongs to the ABC transporter superfamily
OOONCIOL_03077 2.3e-170 oppF E Belongs to the ABC transporter superfamily
OOONCIOL_03078 9.8e-230 S Putative glycosyl hydrolase domain
OOONCIOL_03079 1.3e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OOONCIOL_03080 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OOONCIOL_03081 4.7e-109 yjbE P Integral membrane protein TerC family
OOONCIOL_03082 6e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OOONCIOL_03083 2.1e-216 yjbF S Competence protein
OOONCIOL_03084 0.0 pepF E oligoendopeptidase F
OOONCIOL_03085 5.8e-19
OOONCIOL_03086 6.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OOONCIOL_03087 4.8e-72 yjbI S Bacterial-like globin
OOONCIOL_03088 5.1e-114 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OOONCIOL_03089 1.2e-95 yjbK S protein conserved in bacteria
OOONCIOL_03090 2.5e-59 yjbL S Belongs to the UPF0738 family
OOONCIOL_03091 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
OOONCIOL_03092 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OOONCIOL_03093 2.2e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OOONCIOL_03094 2.6e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
OOONCIOL_03095 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OOONCIOL_03096 4.9e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OOONCIOL_03097 7.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
OOONCIOL_03098 2.3e-209 thiO 1.4.3.19 E Glycine oxidase
OOONCIOL_03099 6.7e-30 thiS H Thiamine biosynthesis
OOONCIOL_03100 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
OOONCIOL_03101 6.7e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OOONCIOL_03102 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OOONCIOL_03103 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
OOONCIOL_03104 1.9e-88 yjbX S Spore coat protein
OOONCIOL_03105 6.7e-83 cotZ S Spore coat protein
OOONCIOL_03106 4.6e-93 cotY S Spore coat protein Z
OOONCIOL_03107 5.1e-71 cotX S Spore Coat Protein X and V domain
OOONCIOL_03108 6.8e-21 cotW
OOONCIOL_03109 1.4e-52 cotV S Spore Coat Protein X and V domain
OOONCIOL_03110 5.6e-56 yjcA S Protein of unknown function (DUF1360)
OOONCIOL_03114 3.8e-38 spoVIF S Stage VI sporulation protein F
OOONCIOL_03115 0.0 yjcD 3.6.4.12 L DNA helicase
OOONCIOL_03116 1.3e-35
OOONCIOL_03117 2.7e-55 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
OOONCIOL_03118 3.3e-70 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
OOONCIOL_03119 7.5e-124 S ABC-2 type transporter
OOONCIOL_03120 6.4e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
OOONCIOL_03121 2.7e-35 K SpoVT / AbrB like domain
OOONCIOL_03123 2.3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OOONCIOL_03124 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
OOONCIOL_03125 4e-125 yjcH P COG2382 Enterochelin esterase and related enzymes
OOONCIOL_03126 3.3e-211 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OOONCIOL_03127 1.7e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OOONCIOL_03129 7.4e-30
OOONCIOL_03130 1.2e-253 yobL S Bacterial EndoU nuclease
OOONCIOL_03133 1.9e-57 E Glyoxalase-like domain
OOONCIOL_03134 4.3e-161 bla 3.5.2.6 V beta-lactamase
OOONCIOL_03135 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
OOONCIOL_03136 3.5e-250 yfjF EGP Belongs to the major facilitator superfamily
OOONCIOL_03137 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
OOONCIOL_03138 1e-220 ganA 3.2.1.89 G arabinogalactan
OOONCIOL_03139 4.9e-287 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OOONCIOL_03140 3.6e-185 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OOONCIOL_03141 7.4e-214 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OOONCIOL_03142 1.1e-306 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OOONCIOL_03143 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
OOONCIOL_03144 6.9e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
OOONCIOL_03145 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
OOONCIOL_03146 3.9e-122 5.4.2.6 S Haloacid dehalogenase-like hydrolase
OOONCIOL_03147 3.7e-144 N Kelch motif
OOONCIOL_03149 2.4e-105 yhiD S MgtC SapB transporter
OOONCIOL_03150 3.7e-21 yjfB S Putative motility protein
OOONCIOL_03151 2.3e-66 T PhoQ Sensor
OOONCIOL_03152 1.3e-99 yjgB S Domain of unknown function (DUF4309)
OOONCIOL_03153 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
OOONCIOL_03154 4.3e-92 yjgD S Protein of unknown function (DUF1641)
OOONCIOL_03155 4.9e-224 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
OOONCIOL_03156 5.4e-220 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OOONCIOL_03157 6.8e-29
OOONCIOL_03158 5.1e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OOONCIOL_03159 2.1e-124 ybbM S transport system, permease component
OOONCIOL_03160 1.6e-129 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
OOONCIOL_03161 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
OOONCIOL_03162 3.2e-89 yjlB S Cupin domain
OOONCIOL_03163 7e-66 yjlC S Protein of unknown function (DUF1641)
OOONCIOL_03164 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
OOONCIOL_03165 9e-275 uxaC 5.3.1.12 G glucuronate isomerase
OOONCIOL_03166 1.5e-253 yjmB G symporter YjmB
OOONCIOL_03167 7e-181 exuR K transcriptional
OOONCIOL_03168 7.3e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
OOONCIOL_03169 1.7e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
OOONCIOL_03170 1.5e-130 MA20_18170 S membrane transporter protein
OOONCIOL_03171 3.1e-78 yjoA S DinB family
OOONCIOL_03172 2.5e-214 S response regulator aspartate phosphatase
OOONCIOL_03174 2.7e-166 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OOONCIOL_03175 8e-61 yjqA S Bacterial PH domain
OOONCIOL_03176 1.4e-110 yjqB S phage-related replication protein
OOONCIOL_03177 2.9e-110 xkdA E IrrE N-terminal-like domain
OOONCIOL_03178 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
OOONCIOL_03180 3e-150 xkdC L Bacterial dnaA protein
OOONCIOL_03183 2e-10 yqaO S Phage-like element PBSX protein XtrA
OOONCIOL_03184 4.9e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OOONCIOL_03185 4e-110 xtmA L phage terminase small subunit
OOONCIOL_03186 1.4e-210 xtmB S phage terminase, large subunit
OOONCIOL_03187 3e-241 yqbA S portal protein
OOONCIOL_03188 1.7e-90 xkdF 2.1.1.72 L Putative phage serine protease XkdF
OOONCIOL_03189 4.6e-158 xkdG S Phage capsid family
OOONCIOL_03190 3.3e-46 yqbG S Protein of unknown function (DUF3199)
OOONCIOL_03191 5.5e-43 yqbH S Domain of unknown function (DUF3599)
OOONCIOL_03192 6.9e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
OOONCIOL_03193 2e-55 xkdJ
OOONCIOL_03194 8.2e-15
OOONCIOL_03195 7.7e-226 xkdK S Phage tail sheath C-terminal domain
OOONCIOL_03196 2e-74 xkdM S Phage tail tube protein
OOONCIOL_03197 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
OOONCIOL_03198 3.4e-19
OOONCIOL_03199 1.5e-110 xkdP S Lysin motif
OOONCIOL_03200 1.6e-161 xkdQ 3.2.1.96 G NLP P60 protein
OOONCIOL_03201 7.2e-32 xkdR S Protein of unknown function (DUF2577)
OOONCIOL_03202 1.4e-58 xkdS S Protein of unknown function (DUF2634)
OOONCIOL_03203 6.7e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OOONCIOL_03204 8.5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
OOONCIOL_03205 1.2e-26
OOONCIOL_03206 1.7e-91
OOONCIOL_03208 1.6e-28 xkdX
OOONCIOL_03209 1.8e-136 xepA
OOONCIOL_03210 8.7e-38 xhlA S Haemolysin XhlA
OOONCIOL_03211 1.3e-38 xhlB S SPP1 phage holin
OOONCIOL_03212 1.6e-168 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOONCIOL_03213 8.7e-23 spoIISB S Stage II sporulation protein SB
OOONCIOL_03214 1.7e-131 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
OOONCIOL_03215 5.8e-175 pit P phosphate transporter
OOONCIOL_03216 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
OOONCIOL_03217 1.1e-242 steT E amino acid
OOONCIOL_03218 3.7e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
OOONCIOL_03219 1.8e-303 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OOONCIOL_03220 7.1e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OOONCIOL_03222 4.7e-204 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OOONCIOL_03223 2.2e-277 yubD P Major Facilitator Superfamily
OOONCIOL_03225 1.9e-155 dppA E D-aminopeptidase
OOONCIOL_03226 1.2e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOONCIOL_03227 5.5e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOONCIOL_03228 2.2e-190 dppD P Belongs to the ABC transporter superfamily
OOONCIOL_03229 0.0 dppE E ABC transporter substrate-binding protein
OOONCIOL_03230 3.7e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
OOONCIOL_03231 5.9e-197 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OOONCIOL_03232 1.1e-169 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OOONCIOL_03233 1.6e-182 ykfD E Belongs to the ABC transporter superfamily
OOONCIOL_03234 5.6e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
OOONCIOL_03235 1.5e-158 ykgA E Amidinotransferase
OOONCIOL_03236 9.2e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
OOONCIOL_03237 2.4e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OOONCIOL_03238 1.4e-51 ykkC P Multidrug resistance protein
OOONCIOL_03239 1e-48 ykkD P Multidrug resistance protein
OOONCIOL_03240 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
OOONCIOL_03241 5.1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OOONCIOL_03242 1.3e-224 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OOONCIOL_03243 4.1e-69 ohrA O Organic hydroperoxide resistance protein
OOONCIOL_03244 1.1e-72 ohrR K COG1846 Transcriptional regulators
OOONCIOL_03245 4.2e-71 ohrB O Organic hydroperoxide resistance protein
OOONCIOL_03246 3.5e-55 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OOONCIOL_03248 8.4e-215 M Glycosyl transferase family 2
OOONCIOL_03249 1.1e-120 M PFAM Collagen triple helix repeat (20 copies)
OOONCIOL_03250 9.8e-214 hcaT 1.5.1.2 EGP Major facilitator Superfamily
OOONCIOL_03251 7.5e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
OOONCIOL_03252 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OOONCIOL_03253 5e-176 isp O Belongs to the peptidase S8 family
OOONCIOL_03254 4.3e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OOONCIOL_03255 2.1e-132 ykoC P Cobalt transport protein
OOONCIOL_03256 5.9e-302 P ABC transporter, ATP-binding protein
OOONCIOL_03257 1e-97 ykoE S ABC-type cobalt transport system, permease component
OOONCIOL_03258 7.4e-244 ydhD M Glycosyl hydrolase
OOONCIOL_03260 3e-235 mgtE P Acts as a magnesium transporter
OOONCIOL_03261 5.4e-53 tnrA K transcriptional
OOONCIOL_03262 1.9e-16
OOONCIOL_03263 3.1e-26 ykoL
OOONCIOL_03264 1.1e-80 ykoM K transcriptional
OOONCIOL_03265 3.7e-99 ykoP G polysaccharide deacetylase
OOONCIOL_03266 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
OOONCIOL_03267 1e-151 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OOONCIOL_03268 3.8e-99 ykoX S membrane-associated protein
OOONCIOL_03269 1.1e-133 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
OOONCIOL_03270 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOONCIOL_03271 1.5e-118 rsgI S Anti-sigma factor N-terminus
OOONCIOL_03272 2.5e-26 sspD S small acid-soluble spore protein
OOONCIOL_03273 8.6e-125 ykrK S Domain of unknown function (DUF1836)
OOONCIOL_03274 4.5e-155 htpX O Belongs to the peptidase M48B family
OOONCIOL_03275 4.8e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
OOONCIOL_03276 7.2e-113 ydfR S Protein of unknown function (DUF421)
OOONCIOL_03277 8.7e-23 ykzE
OOONCIOL_03278 2.1e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
OOONCIOL_03279 0.0 kinE 2.7.13.3 T Histidine kinase
OOONCIOL_03280 8.6e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OOONCIOL_03282 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OOONCIOL_03283 4.2e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OOONCIOL_03284 7.7e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OOONCIOL_03285 6e-227 mtnE 2.6.1.83 E Aminotransferase
OOONCIOL_03286 3e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
OOONCIOL_03287 4.7e-128 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OOONCIOL_03288 2.6e-112 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
OOONCIOL_03289 7.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OOONCIOL_03290 3.4e-10 S Spo0E like sporulation regulatory protein
OOONCIOL_03291 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
OOONCIOL_03292 5.5e-77 ykvE K transcriptional
OOONCIOL_03293 2.7e-127 motB N Flagellar motor protein
OOONCIOL_03294 3.3e-136 motA N flagellar motor
OOONCIOL_03295 0.0 clpE O Belongs to the ClpA ClpB family
OOONCIOL_03296 1.7e-182 ykvI S membrane
OOONCIOL_03297 2.7e-181
OOONCIOL_03298 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OOONCIOL_03299 3.8e-78 queD 4.1.2.50, 4.2.3.12 H synthase
OOONCIOL_03300 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
OOONCIOL_03301 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OOONCIOL_03302 3.5e-45 ykvR S Protein of unknown function (DUF3219)
OOONCIOL_03303 7.8e-25 ykvS S protein conserved in bacteria
OOONCIOL_03304 7.9e-28
OOONCIOL_03305 5.9e-109 ykvT 3.5.1.28 M Cell Wall Hydrolase
OOONCIOL_03306 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OOONCIOL_03307 1.7e-87 stoA CO thiol-disulfide
OOONCIOL_03308 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OOONCIOL_03309 6.9e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OOONCIOL_03311 3.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
OOONCIOL_03312 5.1e-156 glcT K antiterminator
OOONCIOL_03313 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OOONCIOL_03314 2.1e-39 ptsH G phosphocarrier protein HPr
OOONCIOL_03315 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OOONCIOL_03316 6.1e-38 splA S Transcriptional regulator
OOONCIOL_03317 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
OOONCIOL_03318 7.2e-262 mcpC NT chemotaxis protein
OOONCIOL_03319 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OOONCIOL_03320 4.6e-111 ykwD J protein with SCP PR1 domains
OOONCIOL_03321 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
OOONCIOL_03322 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
OOONCIOL_03323 3.9e-215 patA 2.6.1.1 E Aminotransferase
OOONCIOL_03324 2.3e-09
OOONCIOL_03325 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
OOONCIOL_03326 1.4e-83 ykyB S YkyB-like protein
OOONCIOL_03327 1.5e-239 ykuC EGP Major facilitator Superfamily
OOONCIOL_03328 4.6e-88 ykuD S protein conserved in bacteria
OOONCIOL_03329 3.1e-153 ykuE S Metallophosphoesterase
OOONCIOL_03330 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOONCIOL_03332 3.3e-233 ykuI T Diguanylate phosphodiesterase
OOONCIOL_03333 3.9e-37 ykuJ S protein conserved in bacteria
OOONCIOL_03334 1.4e-92 ykuK S Ribonuclease H-like
OOONCIOL_03335 2.1e-25 ykzF S Antirepressor AbbA
OOONCIOL_03336 1e-75 ykuL S CBS domain
OOONCIOL_03337 1.3e-167 ccpC K Transcriptional regulator
OOONCIOL_03338 1.3e-89 fld C Flavodoxin
OOONCIOL_03339 2.2e-165 ykuO
OOONCIOL_03340 6e-79 fld C Flavodoxin
OOONCIOL_03341 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OOONCIOL_03342 8.8e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OOONCIOL_03343 4.8e-38 ykuS S Belongs to the UPF0180 family
OOONCIOL_03344 3.7e-140 ykuT M Mechanosensitive ion channel
OOONCIOL_03345 2.2e-76 ykuV CO thiol-disulfide
OOONCIOL_03346 4.5e-98 rok K Repressor of ComK
OOONCIOL_03347 3.1e-160 yknT
OOONCIOL_03348 2.8e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
OOONCIOL_03349 1.9e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OOONCIOL_03350 6.4e-243 moeA 2.10.1.1 H molybdopterin
OOONCIOL_03351 1.9e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
OOONCIOL_03352 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
OOONCIOL_03353 1.7e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OOONCIOL_03354 4.4e-105 yknW S Yip1 domain
OOONCIOL_03355 3.9e-167 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OOONCIOL_03356 2e-121 macB V ABC transporter, ATP-binding protein
OOONCIOL_03357 3e-210 yknZ V ABC transporter (permease)
OOONCIOL_03358 1.7e-131 fruR K Transcriptional regulator
OOONCIOL_03359 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
OOONCIOL_03360 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
OOONCIOL_03361 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OOONCIOL_03362 5.4e-35 ykoA
OOONCIOL_03363 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OOONCIOL_03364 1.7e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OOONCIOL_03365 4.7e-235 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
OOONCIOL_03366 5.5e-12 S Uncharacterized protein YkpC
OOONCIOL_03367 6.9e-184 mreB D Rod-share determining protein MreBH
OOONCIOL_03368 2.1e-45 abrB K of stationary sporulation gene expression
OOONCIOL_03369 1.3e-243 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
OOONCIOL_03370 1e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
OOONCIOL_03371 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
OOONCIOL_03372 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OOONCIOL_03373 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OOONCIOL_03374 8.2e-31 ykzG S Belongs to the UPF0356 family
OOONCIOL_03375 3.7e-145 ykrA S hydrolases of the HAD superfamily
OOONCIOL_03376 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OOONCIOL_03378 5.5e-102 recN L Putative cell-wall binding lipoprotein
OOONCIOL_03379 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OOONCIOL_03380 0.0 Q Polyketide synthase of type I
OOONCIOL_03381 0.0 Q polyketide synthase
OOONCIOL_03382 0.0 Q Polyketide synthase of type I
OOONCIOL_03383 0.0 Q Polyketide synthase of type I
OOONCIOL_03384 0.0 Q Polyketide synthase of type I
OOONCIOL_03385 0.0 Q Polyketide synthase of type I
OOONCIOL_03386 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
OOONCIOL_03387 8.7e-209 V Beta-lactamase
OOONCIOL_03388 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OOONCIOL_03389 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OOONCIOL_03390 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OOONCIOL_03391 1.2e-250 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OOONCIOL_03392 8.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
OOONCIOL_03393 6.7e-134 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
OOONCIOL_03394 1.6e-274 speA 4.1.1.19 E Arginine
OOONCIOL_03395 5.9e-42 yktA S Belongs to the UPF0223 family
OOONCIOL_03396 1.8e-118 yktB S Belongs to the UPF0637 family
OOONCIOL_03397 6.3e-24 ykzI
OOONCIOL_03398 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
OOONCIOL_03399 6.8e-83 ykzC S Acetyltransferase (GNAT) family
OOONCIOL_03400 9.7e-294 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
OOONCIOL_03401 2.2e-13 sigC S Putative zinc-finger
OOONCIOL_03402 1.3e-36 ylaE
OOONCIOL_03403 6.7e-24 S Family of unknown function (DUF5325)
OOONCIOL_03404 0.0 typA T GTP-binding protein TypA
OOONCIOL_03405 6.6e-48 ylaH S YlaH-like protein
OOONCIOL_03406 1.4e-33 ylaI S protein conserved in bacteria
OOONCIOL_03407 2.6e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OOONCIOL_03408 6e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
OOONCIOL_03409 8.5e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OOONCIOL_03410 1.3e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
OOONCIOL_03411 8.7e-44 ylaN S Belongs to the UPF0358 family
OOONCIOL_03412 4.2e-212 ftsW D Belongs to the SEDS family
OOONCIOL_03413 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OOONCIOL_03414 8.6e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
OOONCIOL_03415 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OOONCIOL_03416 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
OOONCIOL_03417 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OOONCIOL_03418 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
OOONCIOL_03419 1.9e-50 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
OOONCIOL_03420 2e-163 ctaG S cytochrome c oxidase
OOONCIOL_03421 3.2e-59 ylbA S YugN-like family
OOONCIOL_03422 2.2e-73 ylbB T COG0517 FOG CBS domain
OOONCIOL_03423 1.7e-198 ylbC S protein with SCP PR1 domains
OOONCIOL_03424 2.1e-54 ylbD S Putative coat protein
OOONCIOL_03425 8.8e-37 ylbE S YlbE-like protein
OOONCIOL_03426 1.2e-71 ylbF S Belongs to the UPF0342 family
OOONCIOL_03427 5.5e-43 ylbG S UPF0298 protein
OOONCIOL_03429 6e-97 rsmD 2.1.1.171 L Methyltransferase
OOONCIOL_03430 9.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OOONCIOL_03431 6.3e-216 ylbJ S Sporulation integral membrane protein YlbJ
OOONCIOL_03432 4.4e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
OOONCIOL_03433 1.6e-188 ylbL T Belongs to the peptidase S16 family
OOONCIOL_03434 4.3e-228 ylbM S Belongs to the UPF0348 family
OOONCIOL_03435 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
OOONCIOL_03436 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OOONCIOL_03437 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
OOONCIOL_03438 1.2e-88 ylbP K n-acetyltransferase
OOONCIOL_03439 6.1e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OOONCIOL_03440 2.8e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OOONCIOL_03441 1.2e-77 mraZ K Belongs to the MraZ family
OOONCIOL_03442 1.2e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OOONCIOL_03443 2.9e-52 ftsL D Essential cell division protein
OOONCIOL_03444 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OOONCIOL_03445 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
OOONCIOL_03446 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OOONCIOL_03447 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OOONCIOL_03448 6.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OOONCIOL_03449 2.2e-185 spoVE D Belongs to the SEDS family
OOONCIOL_03450 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OOONCIOL_03451 1.8e-167 murB 1.3.1.98 M cell wall formation
OOONCIOL_03452 4.8e-132 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OOONCIOL_03453 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OOONCIOL_03454 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OOONCIOL_03455 0.0 bpr O COG1404 Subtilisin-like serine proteases
OOONCIOL_03456 4.1e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
OOONCIOL_03457 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOONCIOL_03458 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOONCIOL_03459 1.6e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
OOONCIOL_03460 8e-254 argE 3.5.1.16 E Acetylornithine deacetylase
OOONCIOL_03461 2.2e-38 ylmC S sporulation protein
OOONCIOL_03462 4.4e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
OOONCIOL_03463 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OOONCIOL_03464 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OOONCIOL_03465 1.5e-40 yggT S membrane
OOONCIOL_03466 1.6e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
OOONCIOL_03467 8.9e-68 divIVA D Cell division initiation protein
OOONCIOL_03468 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OOONCIOL_03469 1.2e-61 dksA T COG1734 DnaK suppressor protein
OOONCIOL_03470 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OOONCIOL_03471 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OOONCIOL_03472 1.4e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OOONCIOL_03473 8.8e-232 pyrP F Xanthine uracil
OOONCIOL_03474 5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OOONCIOL_03475 3.6e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OOONCIOL_03476 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OOONCIOL_03477 0.0 carB 6.3.5.5 F Belongs to the CarB family
OOONCIOL_03478 1.2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
OOONCIOL_03479 2.5e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OOONCIOL_03480 2.1e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OOONCIOL_03481 6.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OOONCIOL_03483 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OOONCIOL_03484 1.1e-176 cysP P phosphate transporter
OOONCIOL_03485 1.9e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OOONCIOL_03486 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
OOONCIOL_03487 2.2e-142 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OOONCIOL_03488 5.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
OOONCIOL_03489 5.5e-78 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
OOONCIOL_03490 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
OOONCIOL_03491 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
OOONCIOL_03492 8.5e-154 yloC S stress-induced protein
OOONCIOL_03493 1.5e-40 ylzA S Belongs to the UPF0296 family
OOONCIOL_03494 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
OOONCIOL_03495 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OOONCIOL_03496 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OOONCIOL_03497 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OOONCIOL_03498 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OOONCIOL_03499 6.8e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OOONCIOL_03500 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OOONCIOL_03501 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
OOONCIOL_03502 3.3e-138 stp 3.1.3.16 T phosphatase
OOONCIOL_03503 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
OOONCIOL_03504 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OOONCIOL_03505 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OOONCIOL_03506 1.3e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
OOONCIOL_03507 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OOONCIOL_03508 5.5e-59 asp S protein conserved in bacteria
OOONCIOL_03509 1.4e-303 yloV S kinase related to dihydroxyacetone kinase
OOONCIOL_03510 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
OOONCIOL_03511 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
OOONCIOL_03512 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OOONCIOL_03513 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
OOONCIOL_03514 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OOONCIOL_03515 2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OOONCIOL_03516 4.6e-129 IQ reductase
OOONCIOL_03517 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OOONCIOL_03518 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OOONCIOL_03519 0.0 smc D Required for chromosome condensation and partitioning
OOONCIOL_03520 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OOONCIOL_03521 2.6e-138 S Phosphotransferase enzyme family
OOONCIOL_03522 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OOONCIOL_03523 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OOONCIOL_03524 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OOONCIOL_03525 1.7e-35 ylqC S Belongs to the UPF0109 family
OOONCIOL_03526 1.3e-61 ylqD S YlqD protein
OOONCIOL_03527 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OOONCIOL_03528 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OOONCIOL_03529 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OOONCIOL_03530 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OOONCIOL_03531 1.5e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OOONCIOL_03532 2e-305 ylqG
OOONCIOL_03533 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
OOONCIOL_03534 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
OOONCIOL_03535 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OOONCIOL_03536 7.5e-166 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
OOONCIOL_03537 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OOONCIOL_03538 2.4e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OOONCIOL_03539 7.2e-172 xerC L tyrosine recombinase XerC
OOONCIOL_03540 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OOONCIOL_03541 8.8e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OOONCIOL_03542 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OOONCIOL_03543 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
OOONCIOL_03544 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
OOONCIOL_03545 2.5e-31 fliE N Flagellar hook-basal body
OOONCIOL_03546 1.4e-263 fliF N The M ring may be actively involved in energy transduction
OOONCIOL_03547 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OOONCIOL_03548 2.4e-88 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
OOONCIOL_03549 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
OOONCIOL_03550 2e-71 fliJ N Flagellar biosynthesis chaperone
OOONCIOL_03551 1.1e-46 ylxF S MgtE intracellular N domain
OOONCIOL_03552 8.8e-203 fliK N Flagellar hook-length control protein
OOONCIOL_03553 4.1e-72 flgD N Flagellar basal body rod modification protein
OOONCIOL_03554 5.7e-138 flgG N Flagellar basal body rod
OOONCIOL_03555 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
OOONCIOL_03556 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OOONCIOL_03557 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OOONCIOL_03558 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
OOONCIOL_03559 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
OOONCIOL_03560 2.2e-109 fliP N Plays a role in the flagellum-specific transport system
OOONCIOL_03561 2e-37 fliQ N Role in flagellar biosynthesis
OOONCIOL_03562 5.2e-131 fliR N Flagellar biosynthetic protein FliR
OOONCIOL_03563 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OOONCIOL_03564 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OOONCIOL_03565 6.3e-191 flhF N Flagellar biosynthesis regulator FlhF
OOONCIOL_03566 1.2e-155 flhG D Belongs to the ParA family
OOONCIOL_03567 2.5e-192 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
OOONCIOL_03568 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
OOONCIOL_03569 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
OOONCIOL_03570 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
OOONCIOL_03571 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
OOONCIOL_03572 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOONCIOL_03573 8e-50 ylxL
OOONCIOL_03574 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
OOONCIOL_03575 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OOONCIOL_03576 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OOONCIOL_03577 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OOONCIOL_03578 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OOONCIOL_03579 2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
OOONCIOL_03580 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
OOONCIOL_03581 5.9e-233 rasP M zinc metalloprotease
OOONCIOL_03582 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OOONCIOL_03583 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OOONCIOL_03584 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
OOONCIOL_03585 5.4e-206 nusA K Participates in both transcription termination and antitermination
OOONCIOL_03586 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
OOONCIOL_03587 1.8e-47 ylxQ J ribosomal protein
OOONCIOL_03588 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OOONCIOL_03589 3.9e-44 ylxP S protein conserved in bacteria
OOONCIOL_03590 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OOONCIOL_03591 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OOONCIOL_03592 6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OOONCIOL_03593 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OOONCIOL_03594 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
OOONCIOL_03595 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
OOONCIOL_03596 1.2e-233 pepR S Belongs to the peptidase M16 family
OOONCIOL_03597 2.6e-42 ymxH S YlmC YmxH family
OOONCIOL_03598 1e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
OOONCIOL_03599 5.7e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
OOONCIOL_03600 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OOONCIOL_03601 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OOONCIOL_03602 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OOONCIOL_03603 2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OOONCIOL_03604 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
OOONCIOL_03605 6.3e-31 S YlzJ-like protein
OOONCIOL_03606 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OOONCIOL_03607 4.4e-132 ymfC K Transcriptional regulator
OOONCIOL_03608 3e-227 ymfD EGP Major facilitator Superfamily
OOONCIOL_03609 2.1e-76 K helix_turn_helix multiple antibiotic resistance protein
OOONCIOL_03610 0.0 ydgH S drug exporters of the RND superfamily
OOONCIOL_03611 1.8e-237 ymfF S Peptidase M16
OOONCIOL_03612 1.3e-240 ymfH S zinc protease
OOONCIOL_03613 1.2e-126 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
OOONCIOL_03614 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
OOONCIOL_03615 1e-142 ymfK S Protein of unknown function (DUF3388)
OOONCIOL_03616 2.5e-124 ymfM S protein conserved in bacteria
OOONCIOL_03617 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OOONCIOL_03618 1.2e-230 cinA 3.5.1.42 S Belongs to the CinA family
OOONCIOL_03619 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OOONCIOL_03620 1.1e-193 pbpX V Beta-lactamase
OOONCIOL_03621 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
OOONCIOL_03622 4.9e-153 ymdB S protein conserved in bacteria
OOONCIOL_03623 1.2e-36 spoVS S Stage V sporulation protein S
OOONCIOL_03624 4.8e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
OOONCIOL_03625 2.6e-214 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OOONCIOL_03626 5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OOONCIOL_03627 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
OOONCIOL_03628 1.7e-88 cotE S Spore coat protein
OOONCIOL_03629 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OOONCIOL_03630 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OOONCIOL_03632 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
OOONCIOL_03633 5.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OOONCIOL_03634 4.3e-183 pksD Q Acyl transferase domain
OOONCIOL_03635 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OOONCIOL_03636 5.5e-34 acpK IQ Phosphopantetheine attachment site
OOONCIOL_03637 2.4e-242 pksG 2.3.3.10 I synthase
OOONCIOL_03638 1.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
OOONCIOL_03639 1.1e-138 pksI I Belongs to the enoyl-CoA hydratase isomerase family
OOONCIOL_03640 0.0 rhiB IQ polyketide synthase
OOONCIOL_03641 0.0 Q Polyketide synthase of type I
OOONCIOL_03642 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
OOONCIOL_03643 0.0 dhbF IQ polyketide synthase
OOONCIOL_03644 0.0 pks13 HQ Beta-ketoacyl synthase
OOONCIOL_03645 3.8e-229 cypA C Cytochrome P450
OOONCIOL_03646 1.6e-76 nucB M Deoxyribonuclease NucA/NucB
OOONCIOL_03647 3.6e-118 yoaK S Membrane
OOONCIOL_03648 4.1e-62 ymzB
OOONCIOL_03649 1.7e-254 aprX O Belongs to the peptidase S8 family
OOONCIOL_03651 3e-125 ymaC S Replication protein
OOONCIOL_03652 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
OOONCIOL_03653 2.6e-53 ebrB P Small Multidrug Resistance protein
OOONCIOL_03654 2.6e-47 ebrA P Small Multidrug Resistance protein
OOONCIOL_03656 9.2e-47 ymaF S YmaF family
OOONCIOL_03657 4.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OOONCIOL_03658 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
OOONCIOL_03659 4.7e-42
OOONCIOL_03660 1.8e-20 ymzA
OOONCIOL_03661 3.9e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
OOONCIOL_03662 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OOONCIOL_03663 1.4e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OOONCIOL_03664 2.2e-108 ymaB S MutT family
OOONCIOL_03665 3.6e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOONCIOL_03666 1.3e-176 spoVK O stage V sporulation protein K
OOONCIOL_03667 1.9e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OOONCIOL_03668 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
OOONCIOL_03669 4.3e-68 glnR K transcriptional
OOONCIOL_03670 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
OOONCIOL_03671 1.1e-208 mrjp G Major royal jelly protein
OOONCIOL_03672 4.2e-248 xynT G MFS/sugar transport protein
OOONCIOL_03673 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
OOONCIOL_03674 3.2e-209 xylR GK ROK family
OOONCIOL_03675 4.1e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
OOONCIOL_03677 7.1e-286 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
OOONCIOL_03678 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
OOONCIOL_03682 7e-17
OOONCIOL_03683 4e-122 K WYL domain
OOONCIOL_03684 4.5e-67 S DinB family
OOONCIOL_03685 2.4e-184 adhP 1.1.1.1 C alcohol dehydrogenase
OOONCIOL_03686 2.9e-08 ccmM S Bacterial transferase hexapeptide (six repeats)
OOONCIOL_03688 3.7e-99 J Acetyltransferase (GNAT) domain
OOONCIOL_03689 9.5e-115 ynaE S Domain of unknown function (DUF3885)
OOONCIOL_03690 3.9e-201 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOONCIOL_03691 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
OOONCIOL_03693 3.4e-65 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OOONCIOL_03694 3.6e-91 yvgO
OOONCIOL_03696 0.0 yobO M Pectate lyase superfamily protein
OOONCIOL_03697 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OOONCIOL_03698 5e-140 yndL S Replication protein
OOONCIOL_03699 9.1e-08
OOONCIOL_03700 1e-137 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
OOONCIOL_03701 1.2e-71 yndM S Protein of unknown function (DUF2512)
OOONCIOL_03702 2.1e-12 yoaW
OOONCIOL_03703 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OOONCIOL_03704 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
OOONCIOL_03705 3.5e-112 yneB L resolvase
OOONCIOL_03706 9.8e-33 ynzC S UPF0291 protein
OOONCIOL_03707 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OOONCIOL_03708 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
OOONCIOL_03709 2.3e-28 yneF S UPF0154 protein
OOONCIOL_03710 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
OOONCIOL_03711 1.3e-125 ccdA O cytochrome c biogenesis protein
OOONCIOL_03712 3e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
OOONCIOL_03713 4.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
OOONCIOL_03714 2.5e-74 yneK S Protein of unknown function (DUF2621)
OOONCIOL_03715 1.4e-62 hspX O Spore coat protein
OOONCIOL_03716 2.3e-19 sspP S Belongs to the SspP family
OOONCIOL_03717 7.5e-15 sspO S Belongs to the SspO family
OOONCIOL_03718 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OOONCIOL_03719 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OOONCIOL_03722 7.1e-18 tlp S Belongs to the Tlp family
OOONCIOL_03723 8.3e-75 yneP S Thioesterase-like superfamily
OOONCIOL_03724 1.4e-52 yneQ
OOONCIOL_03725 1.1e-49 yneR S Belongs to the HesB IscA family
OOONCIOL_03726 1.2e-92 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OOONCIOL_03727 1.5e-68 yccU S CoA-binding protein
OOONCIOL_03728 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OOONCIOL_03729 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OOONCIOL_03730 6e-13
OOONCIOL_03731 5.1e-41 ynfC
OOONCIOL_03732 5.2e-246 agcS E Sodium alanine symporter
OOONCIOL_03733 2.6e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
OOONCIOL_03734 1.7e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
OOONCIOL_03735 1.5e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
OOONCIOL_03736 2.7e-210 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
OOONCIOL_03737 1.2e-146 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OOONCIOL_03738 1.3e-179 kdgR_1 K transcriptional
OOONCIOL_03739 2.1e-43 exuT G Sugar (and other) transporter
OOONCIOL_03740 1.2e-164 exuT G Sugar (and other) transporter
OOONCIOL_03741 5.4e-155 yndG S DoxX-like family
OOONCIOL_03742 1.8e-78 yndH S Domain of unknown function (DUF4166)
OOONCIOL_03743 5.5e-292 yndJ S YndJ-like protein
OOONCIOL_03744 4.8e-24 S Platelet-activating factor acetylhydrolase, isoform II
OOONCIOL_03745 5.1e-284 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
OOONCIOL_03746 1.2e-49 S Domain of unknown function (DUF4870)
OOONCIOL_03747 2e-229 T PhoQ Sensor
OOONCIOL_03748 3.2e-127 T Transcriptional regulatory protein, C terminal
OOONCIOL_03749 3.1e-250 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
OOONCIOL_03750 4.7e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
OOONCIOL_03751 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOONCIOL_03752 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOONCIOL_03753 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOONCIOL_03754 7.3e-217 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OOONCIOL_03755 6.4e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
OOONCIOL_03756 7.1e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OOONCIOL_03757 9.9e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OOONCIOL_03758 4.2e-251 yxjC EG COG2610 H gluconate symporter and related permeases
OOONCIOL_03759 5.6e-217 bioI 1.14.14.46 C Cytochrome P450
OOONCIOL_03760 1.1e-192 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OOONCIOL_03761 1.6e-126 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OOONCIOL_03762 3.1e-212 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OOONCIOL_03763 3.6e-257 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
OOONCIOL_03764 1.5e-143 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
OOONCIOL_03765 9.6e-68 yngA S membrane
OOONCIOL_03766 2.6e-158 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OOONCIOL_03767 3.2e-104 yngC S SNARE associated Golgi protein
OOONCIOL_03768 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OOONCIOL_03769 4.4e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OOONCIOL_03770 3.6e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
OOONCIOL_03771 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
OOONCIOL_03772 7.9e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
OOONCIOL_03773 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OOONCIOL_03774 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
OOONCIOL_03775 1.5e-299 yngK T Glycosyl hydrolase-like 10
OOONCIOL_03776 1.6e-64 yngL S Protein of unknown function (DUF1360)
OOONCIOL_03777 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
OOONCIOL_03778 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOONCIOL_03779 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOONCIOL_03780 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOONCIOL_03781 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOONCIOL_03782 1.9e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
OOONCIOL_03783 1e-184 yoxA 5.1.3.3 G Aldose 1-epimerase
OOONCIOL_03784 6.7e-246 yoeA V MATE efflux family protein
OOONCIOL_03785 1.9e-95 yoeB S IseA DL-endopeptidase inhibitor
OOONCIOL_03786 4.4e-205 yobL S Bacterial EndoU nuclease
OOONCIOL_03787 3e-27 S SMI1 / KNR4 family
OOONCIOL_03789 3e-70 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOONCIOL_03790 8.4e-67 S Pfam:Phage_holin_4_1
OOONCIOL_03793 5.7e-164 S Domain of unknown function (DUF2479)
OOONCIOL_03794 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
OOONCIOL_03795 8.5e-227 NU Prophage endopeptidase tail
OOONCIOL_03796 7.6e-112 S Phage tail protein
OOONCIOL_03797 0.0 S peptidoglycan catabolic process
OOONCIOL_03798 1.5e-11
OOONCIOL_03799 9.2e-24
OOONCIOL_03800 4.4e-61
OOONCIOL_03801 1.5e-30
OOONCIOL_03802 5.1e-47 S Bacteriophage HK97-gp10, putative tail-component
OOONCIOL_03803 3.6e-15 S Phage head-tail joining protein
OOONCIOL_03804 1.2e-23 S Phage gp6-like head-tail connector protein
OOONCIOL_03805 2.6e-44 S peptidoglycan catabolic process
OOONCIOL_03807 8.3e-221 S peptidase activity
OOONCIOL_03808 3e-113 S peptidase activity
OOONCIOL_03809 1.5e-241 S Phage portal protein
OOONCIOL_03810 1.8e-10
OOONCIOL_03811 3.3e-231 S Phage Terminase
OOONCIOL_03812 3.9e-87 S Phage terminase, small subunit
OOONCIOL_03813 7.5e-23
OOONCIOL_03814 2.4e-65 S HNH endonuclease
OOONCIOL_03817 3.1e-17
OOONCIOL_03818 5e-72 L Phage integrase family
OOONCIOL_03819 5.7e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
OOONCIOL_03820 8.1e-43 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OOONCIOL_03821 2.4e-45
OOONCIOL_03823 1.6e-106 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
OOONCIOL_03826 2.8e-15 yqaO S Phage-like element PBSX protein XtrA
OOONCIOL_03830 2.9e-27
OOONCIOL_03831 2.8e-42 dnaC L IstB-like ATP binding protein
OOONCIOL_03832 2.4e-84 ybl78 L Conserved phage C-terminus (Phg_2220_C)
OOONCIOL_03834 2.8e-38 S Domain of unknown function (DUF771)
OOONCIOL_03835 7.8e-22 K Helix-turn-helix XRE-family like proteins
OOONCIOL_03838 4.7e-69
OOONCIOL_03839 8.8e-116 L Phage integrase family
OOONCIOL_03841 1.7e-96 L Integrase
OOONCIOL_03842 1.8e-34 yoeD G Helix-turn-helix domain
OOONCIOL_03843 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OOONCIOL_03844 2.2e-197 ybcL EGP Major facilitator Superfamily
OOONCIOL_03845 1.8e-50 ybzH K Helix-turn-helix domain
OOONCIOL_03847 4.1e-153 gltR1 K Transcriptional regulator
OOONCIOL_03848 2.1e-182 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
OOONCIOL_03849 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
OOONCIOL_03850 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
OOONCIOL_03851 4.5e-150 gltC K Transcriptional regulator
OOONCIOL_03852 1.8e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OOONCIOL_03853 1.8e-139 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OOONCIOL_03854 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
OOONCIOL_03855 1.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OOONCIOL_03856 3.1e-39 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OOONCIOL_03857 3.2e-133 yoxB
OOONCIOL_03858 1.3e-203 yoaB EGP Major facilitator Superfamily
OOONCIOL_03859 5.9e-269 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
OOONCIOL_03860 2.8e-193 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OOONCIOL_03861 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OOONCIOL_03864 1.5e-95 hpr K helix_turn_helix multiple antibiotic resistance protein
OOONCIOL_03865 6.7e-44
OOONCIOL_03866 1.9e-130 IQ Enoyl-(Acyl carrier protein) reductase
OOONCIOL_03867 5.8e-61 ykvN K Transcriptional regulator
OOONCIOL_03868 1.1e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
OOONCIOL_03869 5.6e-132 yobQ K helix_turn_helix, arabinose operon control protein
OOONCIOL_03870 5.4e-93 yobS K Transcriptional regulator
OOONCIOL_03871 7.2e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
OOONCIOL_03872 4.6e-91 yobW
OOONCIOL_03873 8.4e-54 czrA K transcriptional
OOONCIOL_03874 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OOONCIOL_03875 3.6e-91 yozB S membrane
OOONCIOL_03876 4e-139 yocB J Protein required for attachment to host cells
OOONCIOL_03877 1.6e-93 yocC
OOONCIOL_03878 5.5e-186 yocD 3.4.17.13 V peptidase S66
OOONCIOL_03880 2.2e-114 yocH CBM50 M COG1388 FOG LysM repeat
OOONCIOL_03881 0.0 recQ 3.6.4.12 L DNA helicase
OOONCIOL_03882 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OOONCIOL_03884 8.6e-55 dksA T general stress protein
OOONCIOL_03885 1e-09 yocL
OOONCIOL_03886 7.5e-09
OOONCIOL_03887 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
OOONCIOL_03888 3.8e-44 yozN
OOONCIOL_03889 8.5e-37 yocN
OOONCIOL_03890 2.4e-56 yozO S Bacterial PH domain
OOONCIOL_03892 3.6e-31 yozC
OOONCIOL_03893 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
OOONCIOL_03894 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
OOONCIOL_03895 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
OOONCIOL_03896 3.3e-234 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OOONCIOL_03897 2.3e-160 yocS S -transporter
OOONCIOL_03898 1.1e-138 S Metallo-beta-lactamase superfamily
OOONCIOL_03899 2.1e-182 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
OOONCIOL_03900 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
OOONCIOL_03901 0.0 yojO P Von Willebrand factor
OOONCIOL_03902 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
OOONCIOL_03903 1.9e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OOONCIOL_03904 9.2e-220 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)